format-version: 1.2 data-version: releases/2026-02-14 subsetdef: AISM:0000171 "" idspace: cito http://purl.org/spar/cito/ idspace: doap http://usefulinc.com/ns/doap# idspace: obo1 http://www.geneontology.org/formats/oboInOwl#http://purl.obolibrary.org/obo/ idspace: oboI http://www.geneontology.org/formats/oboInOwl# idspace: oboInOwl ttp://www.geneontology.org/formats/oboInOwl# idspace: protege http://protege.stanford.edu/plugins/owl/protege# idspace: skos http://www.w3.org/2004/02/skos/core# idspace: swrl http://www.w3.org/2003/11/swrl# idspace: swrla http://swrl.stanford.edu/ontologies/3.3/swrla.owl# idspace: swrlb http://www.w3.org/2003/11/swrlb# idspace: term http://purl.org/dc/terms/ idspace: terms http://www.geneontology.org/formats/oboInOwl#http://purl.org/dc/terms/ idspace: x_0.1 http://xmlns.com/foaf/0.1/ idspace: x_1.1 http://purl.org/dc/elements/1.1/ ontology: aism property_value: IAO:0000700 "http://purl.obolibrary.org/obo/AISM_0000174" xsd:string property_value: IAO:0000700 "http://purl.obolibrary.org/obo/PATO_0000001" xsd:string property_value: IAO:0000700 "http://purl.obolibrary.org/obo/UBERON_0001062" xsd:string property_value: owl:versionInfo "2026-02-14" xsd:string property_value: term:license https://creativecommons.org/licenses/by/4.0/ property_value: x_1.1:contributor "Giulio Montanaro (gmontanaro) https://orcid.org/0000-0003-0836-1364" xsd:string property_value: x_1.1:contributor "István Mikó (imiko) https://orcid.org/0000-0003-2938-9075" xsd:string property_value: x_1.1:contributor "Jennifer C. Girón (jgiron) https://orcid.org/0000-0002-0851-6883" xsd:string property_value: x_1.1:contributor "Luis A. González Montaña (lagonzalezmo) https://orcid.org/0000-0002-9136-9932" xsd:string property_value: x_1.1:contributor "Sergei Tarasov (starasov) https://orcid.org/0000-0001-5237-2330" xsd:string property_value: x_1.1:description "The ontology for the Anatomy of the Insect SkeletoMuscular system (AISM) contains terms used to describe the cuticle - as a single anatomical structure - and the skeletal muscle system, to be used in insect biodiversity research." xsd:string property_value: x_1.1:title "Ontology for the Anatomy of the Insect SkeletoMuscular system" xsd:string [Term] id: AISM:0000000 name: cuticular internal depression def: "The projection of the inner surface of the cuticle." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-05-19"} is_a: AISM:0000174 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect region of cuticle relationship: BFO:0000050 BSPO:0000061 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! part of proximal side relationship: RO:0000053 PATO:0001857 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! has characteristic concave [Term] id: AISM:0000001 name: resilin {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} def: "Resilin is an elastomeric protein found in many insects and other arthropods. It provides soft rubber-elasticity to mechanically active organs and tissue.\nhttps://en.wikipedia.org/wiki/Resilin" [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} is_a: PR:000000001 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} ! protein property_value: IAO:0000232 "This is a generalized term to refer to this protein as the only option available now is pro-resilin (fruit fly) [http://purl.obolibrary.org/obo/PR_Q9V7U0]" xsd:string {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} [Term] id: AISM:0000002 name: insect articulation def: "The region of cuticle that is composed two articular surfaces that are adjacent to each other." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-10-27"} is_a: AISM:0000174 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect region of cuticle property_value: IAO:0000232 "Articulations are 'anatomical clusters', collections of not direclty connected (continuous) sclerite surfaces that are adjacent to another sclerite. The cranio-mandibular articulation is the articular surface of the cranium and the adjacent articular surface of the mandible. The articular surfaces are sometimes located on the same sclerite." xsd:string {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} [Term] id: AISM:0000003 name: insect sclerite {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Sclerite: distinctly sclerotized region of the integument, with thick layer of exocuticle.\"", IAO:0000232="Modified 2023-01-09: specifying insect sclerite.\njgiron https://orcid.org/0000-0002-0851-6883"} def: "The region of the insect cuticle that is less flexible than the neighboring conjunctiva(e) (conjunctiva(e) that the sclerite is continuous with." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-10-27"} xref: http://flybase.org/cgi-bin/fbcvq.html?query=FBbt\:00004475 "sclerite" xref: http://purl.obolibrary.org/obo/HAO_0000909 "sclerite" {def="The area of the cuticle that is less flexible than adjacent conjunctivae."} xref: http://purl.obolibrary.org/obo/UBERON_6004475 "insect sclerite" is_a: AISM:0000174 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect region of cuticle property_value: IAO:0000118 "esclerito" xsd:string {creation_date="2023-01-09"} [Term] id: AISM:0000004 name: conjunctiva def: "The region of the insect cuticle that is more flexible than the neighboring sclerite(s) [sclerite(s) that the conjunctiva is continuous with]." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-10-27"} synonym: "membrane" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Membrane: very flexible, unsclerotized area of the integument.\""} xref: http://purl.obolibrary.org/obo/HAO_0000221 "conjunctiva" {def="The area of the cuticle that is more flexible than adjacent sclerites."} is_a: AISM:0000174 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect region of cuticle relationship: RO:0002150 AISM:0000003 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! continuous with insect sclerite property_value: IAO:0000232 "Conjunctivae are more flexible and usually less thick than sclerties of the cuticle allowing the sclerites to move relative to each other.\nMicro-CT based methods cannot be used to accurately differentiate slcerites from conjunctiuvae. CLSM (the excitation wavelengths of sclerites and conjunctivae are different in response of 488 nm emission vawelength), histological sections or simple dissections need to be applied to define relative flexibility of the insect cuticle.\n\nIf a conjunctiva entirelly encircles a sclerite, then the 'encircles' and 'encircled by' object properties are used to link the sclerite and the conjunctiva even in cases in which the encircled sclerites or conjunctivae are part of an evagination allowing to model spatial relationship between appendage segments: the pedicel is encircled by the scapal-pedicellar conjunctiva, which is encircled by the scape or the the coxa encircles the coxo-femoral conjunctiuva that encircels the femur." xsd:string {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} [Term] id: AISM:0000005 name: cuticular depression def: "The region of the cuticle that corresponds to a concave surface." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-10-27"} is_a: BFO:0000004 ! independent continuant relationship: BSPO:0000125 AISM:0000174 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! in distal side of insect region of cuticle relationship: RO:0000053 PATO:0001857 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! has characteristic concave property_value: IAO:0000232 "External cuticular depression. The surface of the cuticle in insects is the entire surface of an organism, and it is composed of flat, concave and convex regions. Concavities sometimes correspons with invaginations of the cuticle and the underlaying sinlge layer epidermis, somtimes correspond to a decreased cuticular thickness." xsd:string {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} [Term] id: AISM:0000006 name: cuticular invagination def: "The region of cuticle that corresponds with an invagination of the single layer epidermis (epidermal fold). The cuticular invagination sometimes corresponds to a cuticular depression (concavity on the surface of the cuticle)." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-10-27"} is_a: AISM:0000174 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect region of cuticle relationship: RO:0002008 AISM:0000000 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coincident with cuticular internal depression relationship: RO:0002008 AISM:0000005 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coincident with cuticular depression [Term] id: AISM:0000007 name: elastic cuticle {creation_date="2020-10-27"} def: "The region of cuticle with higher content of resilin." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect region of cuticle is_a: PR:000050567 ! protein-containing material entity relationship: RO:0002473 AISM:0000001 {IAO:0000232="Modified 2024-02-14: updated to 'composed primarily of' and linked to resilin\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! composed primarily of resilin [Term] id: AISM:0000008 name: cuticular protrusion def: "The region of the cuticle that corresponds to a convex surface." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-10-27"} is_a: AISM:0000174 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect region of cuticle relationship: BFO:0000050 BSPO:0000062 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! part of distal side relationship: RO:0000053 PATO:0001355 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! has characteristic convex property_value: IAO:0000232 "The surface of the cuticle in insects is the entire surface of an organism, and it is composed of flat, concave and convex regions. Convexities sometimes correspons with evaginations of the cuticle and the underlaying sinlge layer epidermis and sometimes correspond to an increased cuticular thickness.\"" xsd:string {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} [Term] id: AISM:0000009 name: cuticular fossa {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} def: "The cuticular depression that is adjacent to a cuticular condyle." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} is_a: AISM:0000005 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} ! cuticular depression relationship: RO:0002220 AISM:0000010 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} ! adjacent to cuticular condyle [Term] id: AISM:0000010 name: cuticular condyle {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} def: "The cuticular protrusion that is part of an insect sclerite and adjacent to an articular surface." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} is_a: AISM:0000008 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} ! cuticular protrusion relationship: BFO:0000050 AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} ! part of insect sclerite relationship: RO:0002220 AISM:0000167 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} ! adjacent to articular surface [Term] id: AISM:0000013 name: evaginated {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-10-27"} def: "A part or structure that is produced by evagination." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"} is_a: PATO:0001355 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! convex [Term] id: AISM:0000014 name: insect cranio-mandibular articulation {IAO:0000232="Modified 2023-02-05: specified insect.\njgiron https://orcid.org/0000-0002-0851-6883"} def: "The articulation between the mandible and the cranium." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-10-27"} is_a: AISM:0000002 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect articulation [Term] id: AISM:0000015 name: cranio-cardinal articulation def: "The articulation between the cardo and the head capsule." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-10-27"} is_a: AISM:0000002 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect articulation [Term] id: AISM:0000016 name: cranio-antennal articulation def: "The articulation between the scapus and the cranium." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-10-27"} is_a: AISM:0000002 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect articulation [Term] id: AISM:0000017 name: insect head-cervical articulation {IAO:0000232="Modified 2023-02-05: specified insect.\njgiron https://orcid.org/0000-0002-0851-6883"} def: "The articulation between the head and the neck." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-10-27"} is_a: AISM:0000002 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect articulation [Term] id: AISM:0000018 name: cardo {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043\n\n\"Cardo: basal element of maxilla, articulating with head capsule; usually moved by one cranial muscle and one tentorial muscle.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The sclerite of the insect maxilla that is attached to the head capsule by the oral foraminal conjunctiva and to the cuticle of stipes by the stipito-cardinal conjunctiva." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000003 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite relationship: BFO:0000050 AISM:0000044 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect maxilla relationship: RO:0002150 AISM:0000099 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! continuous with oral foraminal conjunctiva relationship: RO:0002150 AISM:0000110 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! continuous with cardo-stipital conjunctiva relationship: RO:0002220 AISM:0000019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to head capsule relationship: RO:0002220 AISM:0000111 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! adjacent to stipes property_value: IAO:0000589 "cuticle of cardo" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000019 name: head capsule {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"The head capsule is almost always a rigid, well sclerotized structural unit, equipped with a defined set of appendages. It is reinforced by strengthening ridges and the endoskeletal tentorium\""} def: "The sclerite of the insect head that is attached to the neck membrane and the oral foraminal conjunctiva, bears the eye cuticle and surrounds the brain" [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} synonym: "cephalic capsule" EXACT [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} synonym: "insect cranium" EXACT [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000003 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite relationship: AISM:0000078 AISM:0000099 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircles oral foraminal conjunctiva relationship: BFO:0000050 AISM:0000107 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect head relationship: BFO:0000051 AISM:0000088 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! has part eye cuticle relationship: RO:0002150 AISM:0000098 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! continuous with neck membrane relationship: RO:0002221 UBERON:0000955 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! surrounds brain [Term] id: AISM:0000020 name: dorsal second axillary sclerite def: "The axillary sclerite that is on the dorsal region of the basal wing conjunctiva and lateral to the first axillary sclerite." [] {creation_date="2021-04-10", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004161 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! axillary sclerite relationship: AISM:0000011 AISM:0000022 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! lateral_to first axillary sclerite [Term] id: AISM:0000021 name: abdominal tergite I def: "Is the abdominal tergite of the preabdomen that is attached to the posterior margin of the tergum by the metanoto-abdominal tergite I conjunctiva." [] {IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0004057 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite relationship: anteriorly_connected_to AISM:0004082 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metanoto-abdominal tergite I conjunctiva relationship: BFO:0000050 AISM:0004055 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of preabdomen [Term] id: AISM:0000022 name: first axillary sclerite def: "The axillary sclerite that is part of the dorsal region of the basal wing conjunctiva and is anterior to the third axillary sclerite." [] {creation_date="2021-04-10", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004161 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! axillary sclerite relationship: BSPO:0000096 AISM:0004223 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! anterior to third axillary sclerite [Term] id: AISM:0000023 name: galea {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Galea: outer endite lobe of maxilla, usually semimembranous and equipped with sensilla (mainly chemoreceptors).\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the appendage of the insect maxilla that is attached to the stipes by the stipito-galeal conjunctiva." [] {term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000029 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect appendage relationship: BFO:0000050 AISM:0000044 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect maxilla relationship: RO:0002150 AISM:0004011 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with stipito-galeal conjunctiva relationship: RO:0002220 AISM:0000111 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to stipes property_value: IAO:0000589 "cuticle of galea" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000024 name: labial palpus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Labial palp: tactile appendage of the labium.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the paired appendage of the labium that is attached to the palpiger by the palpigero-palpal conjunctiva." [] {term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000029 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect appendage relationship: AISM:0000079 AISM:0004017 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by palpigero-palpal conjunctiva relationship: BFO:0000050 AISM:0000087 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of labium relationship: RO:0000053 PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has characteristic bilaterally paired relationship: RO:0002220 AISM:0004006 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to palpiger property_value: IAO:0000589 "cuticle of labial palpus" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000026 name: lacinia {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Lacinia: inner endite lobe of maxilla, usually firmly connected or fused with stipes; usually sclerotized, with mesally curved apex and articulated spines arranged along mesal edge.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the appendage of the insect maxilla that is attached to the cuticle of stipes by the stipito-lacinial conjunctiva." [] {term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000029 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect appendage relationship: BFO:0000050 AISM:0000044 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! part of insect maxilla relationship: RO:0002150 AISM:0004009 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with stipito-lacinial conjunctiva relationship: RO:0002220 AISM:0000111 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to stipes property_value: IAO:0000589 "cuticle of lacinia" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000027 name: cuticular evagination def: "The region of cuticle that corresponds with an evagination of the cuticle and the single layer epidermis (epidermal fold). The cuticular evagination usually corresponds to a cuticular protrusion (convexity on the surface of the cuticle)." [] {creation_date="2020-11-11", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000008 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular protrusion intersection_of: AISM:0000008 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! cuticular protrusion intersection_of: RO:0000053 AISM:0000013 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! has characteristic evaginated intersection_of: RO:0002008 UBERON:0005157 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! coincident with epithelial fold relationship: RO:0000053 AISM:0000013 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! has characteristic evaginated relationship: RO:0002008 UBERON:0005157 {creation_date="imiko https://orcid.org/0000-0003-2938-9075"} ! coincident with epithelial fold [Term] id: AISM:0000028 name: solid cuticular protrusion {creation_date="2020-11-11"} def: "The cuticular protrusion that does not correspond to an evagination." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"} is_a: AISM:0000008 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular protrusion [Term] id: AISM:0000029 name: insect appendage {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"any part, piece, or organ attached by a joint to the body or to any other main structure\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The evagination of the cuticle that is musculated (connected to the body via muscles)." [] {creation_date="2020-11-11", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000128 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! multicellular cuticular evagination intersection_of: AISM:0000128 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! multicellular cuticular evagination intersection_of: RO:0002150 UBERON:0014895 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! continuous with somatic muscle, invertebrate relationship: RO:0002150 UBERON:0014895 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! continuous with somatic muscle, invertebrate property_value: IAO:0000589 "cuticle of insect appendage" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000031 name: insect leg {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the paired appendage of the insect thorax that is composed of coxa, trochanter, femur, tibia, tarsus, and pretarsus." [] {term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0000029 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect appendage relationship: BFO:0000050 AISM:0000108 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect thorax relationship: BFO:0000051 AISM:0000047 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part distitarsus relationship: BFO:0000051 AISM:0000075 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part tibia relationship: BFO:0000051 AISM:0000076 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part femur relationship: BFO:0000051 AISM:0000077 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part coxa relationship: BFO:0000051 AISM:0004168 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part trochanter relationship: BFO:0000051 AISM:0004169 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part tarsus relationship: RO:0000053 PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has characteristic bilaterally paired property_value: IAO:0000589 "cuticle of insect leg" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000032 name: antenna {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043\n\n\"Antenna: head appendage of segment 2, innervated by deutocerebrum; in Insecta composed of scapus, pedicellus and flagellum; primarily multisegmented and filiform.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the appendage of the head capsule that is connected by the antenniferal-scapal conjunctiva to the cuticle of the scapus, which is connected by the scapal-pedicellar conjunctiva to the cuticle of the pedicellus; the cuticle of the pedicellus is connected by the pedicellar-first flagellomeral conjunctiva to the cuticle of the first flagellomere; the cuticle of the first flagellomere is connected by interflagellomeral conjunctiva to the next cuticle of flagellomere. Further cuticle of flagellomeres are connected to each other by interflagellomeral conjunctiva." [] {term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000029 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect appendage relationship: AISM:0000079 AISM:0004007 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by antenniferal-scapal conjunctiva relationship: BFO:0000050 UBERON:6003007 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect adult head relationship: BFO:0000051 AISM:0000113 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part scapus relationship: BFO:0000051 AISM:0000114 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part scapal-pedicellar conjunctiva relationship: BFO:0000051 AISM:0000115 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part pedicellus relationship: BFO:0000051 AISM:0000117 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part flagellomere 1 relationship: BFO:0000051 AISM:0000118 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part pedicellar-first flagellomeral conjunctiva relationship: BFO:0000051 AISM:0004008 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part interflagellomeral conjunctiva relationship: RO:0000053 PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has characteristic bilaterally paired property_value: IAO:0000589 "cuticle of antenna" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000033 name: insect wing {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"in adult insects or subimago of Ephemeroptera, paired mambranous appendages, supported by veins, located on the mesothorax or metathorax, functioning in flight\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the flat, paired appendage on the dorso-lateral region of the pterothorax." [] {term:modified="2021-12-08", creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000029 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect appendage relationship: RO:0000053 PATO:0000407 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! has characteristic flat relationship: RO:0000053 PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has characteristic bilaterally paired property_value: IAO:0000589 "cuticle of insect wing" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000034 name: fore leg {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the paired appendage of the prothorax that is anterior to the cuticle of a mid leg and composed of cuticle of procoxa, cuticle of protrochanter, cuticle of profemur, cuticle of protibia, cuticle of protarsus, and cuticle of propretarsus." [] {creation_date="2021-04-03", term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000031 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect leg relationship: BFO:0000050 AISM:0004125 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of prothorax relationship: BFO:0000051 AISM:0000066 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part procoxa relationship: BFO:0000051 AISM:0000067 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part protibia relationship: BFO:0000051 AISM:0000070 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part profemur relationship: BFO:0000051 AISM:0004171 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part protrochanter relationship: BFO:0000051 AISM:0004190 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part protarsus relationship: BFO:0000051 AISM:0004194 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part prodistitarsus relationship: BSPO:0000096 AISM:0000035 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anterior to mid leg property_value: IAO:0000589 "cuticle of fore leg" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000035 name: mid leg {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the paired appendage of the mesothorax that is posterior to the cuticle of a fore leg, anterior to the cuticle of a hind leg, and composed of cuticle of mesocoxa, cuticle of mesotrochanter, cuticle of mesofemur, cuticle of mesotibia, cuticle of mesotarsus, and cuticle of mesopretarsus." [] {creation_date="2021-04-03", term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000031 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect leg relationship: BFO:0000050 AISM:0004126 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of mesothorax relationship: BFO:0000051 AISM:0000064 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part mesocoxa relationship: BFO:0000051 AISM:0000068 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part mesotibia relationship: BFO:0000051 AISM:0000071 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part mesofemur relationship: BFO:0000051 AISM:0004172 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part mesotrochanter relationship: BFO:0000051 AISM:0004189 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part mesotarsus relationship: BFO:0000051 AISM:0004195 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part mesodistitarsus relationship: BSPO:0000096 AISM:0000036 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anterior to hind leg relationship: BSPO:0000099 AISM:0000034 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! posterior to fore leg property_value: IAO:0000589 "cuticle of mid leg" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000036 name: hind leg {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the paired appendage of the metathorax that is posterior to the cuticle of a mid leg and composed of cuticle of metacoxa, cuticle of metatrochanter, cuticle of metafemur, cuticle of metatibia, cuticle of metatarsus, and cuticle of metapretarsus." [] {creation_date="2021-04-03", term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000031 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect leg relationship: BFO:0000050 AISM:0004127 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of metathorax relationship: BFO:0000051 AISM:0000065 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part metacoxa relationship: BFO:0000051 AISM:0000069 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part metatibia relationship: BFO:0000051 AISM:0000072 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part metafemur relationship: BFO:0000051 AISM:0004173 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part metatrochanter relationship: BFO:0000051 AISM:0004188 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part metatarsus relationship: BFO:0000051 AISM:0004196 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part metadistitarsus relationship: BSPO:0000099 AISM:0000035 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! posterior to mid leg property_value: IAO:0000589 "cuticle of hind leg" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000037 name: fore wing {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the paired insect wing that is continuous with the mesonotum." [] {term:modified="2021-12-08", creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000033 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect wing relationship: RO:0002150 AISM:0000052 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! continuous with mesonotum property_value: IAO:0000589 "cuticle of fore wing" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000038 name: hind wing {IAO:0000232="2021-12-08Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the paired insect wing that is continuous with the metanotum." [] {term:modified="2021-12-08", creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000033 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect wing relationship: RO:0002150 AISM:0000169 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! continuous with metanotum property_value: IAO:0000589 "cuticle of hind wing" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000039 name: cuticular seta {creation_date="2020-11-11", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Seta (=macrotrichium): articulated hair with socket, formed by trichogen cell.\"", term:modified="2021-12-10"} def: "The unicellular cuticular evagination that constitutes a sclerite with its base surrounded by socket membrane." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000003 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite is_a: AISM:0000127 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! unicellular cuticular evagination relationship: AISM:0000079 AISM:0000102 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by ring conjunctiva [Term] id: AISM:0000040 name: cuticular spur {source="https://doi.org/10.1016/0020-7322(79)90013-8", AISM:0000171="Richards AG, Richards PA (1979) The cuticular protuberances of insects. International Journal of Insect Morphology and Embryology 8: 143–157. \n\n\"Multicellular protuberances without differentiation of specialized cells\"", term:modified="2021-12-10"} def: "The multicellular evagination of the cuticle that corresponds to an epithelial fold, composed of some sclerite that is encricled by a conjunctiva (moveable)." [] {creation_date="2020-11-11", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000003 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite is_a: AISM:0000128 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! multicellular cuticular evagination relationship: AISM:0000079 AISM:0000102 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by ring conjunctiva property_value: IAO:0000232 "The difference between an appendage and a spur is the lack of muscles attached to the spur, otherwise, the mandible would be also a spur. Spines are multicellular evaginations that are not encircled by conjunctivae. Moveable beetle horns are spurs while not moveable beetle horns are spines." xsd:string {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-11-11"} [Term] id: AISM:0000041 name: cuticular scale {term:modified="2021-12-10"} def: "The seta that is flat." [] {creation_date="2020-11-11", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000039 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular seta relationship: RO:0000053 PATO:0002254 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! has characteristic flattened [Term] id: AISM:0000042 name: labrum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Labrum: unpaired upper lip, connected with distal edge of clypeus.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the mouthpart and appendage that is attached to the clypeus by the clypeo-labral conjunctiva and to the proximal margin of the epipharynx." [] {term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000165 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! mouthpart relationship: RO:0002150 AISM:0004018 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with clypeo-labral conjunctiva relationship: RO:0002220 AISM:0004019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to clypeus property_value: IAO:0000589 "cuticle of labrum" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000043 name: insect mandible {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043\n\n\"The mandibles are the paired appendages of the 4th head segment and receive their innervation from the anterior part of the suboesophageal ganglion [...] They are primarily a compact, undivided and strongly sclerotized element without appendages.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the mouthpart and sclerite between the cuticle of the labrum and the cuticle of the insect maxilla that is attached to the head capsule by the oral foraminal conjunctiva and the cranio-mandibular muscle." [] {term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000003 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite is_a: AISM:0000165 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! mouthpart relationship: BSPO:0000096 AISM:0000044 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! anterior to insect maxilla relationship: BSPO:0000099 AISM:0000042 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! posterior to labrum relationship: RO:0000053 PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has characteristic bilaterally paired relationship: RO:0002150 AISM:0000082 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! continuous with cranio-mandibular muscle relationship: RO:0002220 AISM:0000019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to head capsule property_value: IAO:0000589 "cuticle of insect mandible" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000044 name: insect maxilla {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043\n\n\"Maxilla: head appendage of segment 5, innervated by maxillary nerve originating from intermediate part of suboesophageal complex; primarily composed of cardo, stipes, endite lobes (lacinia, galea) and maxillary palp.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the mouthpart appendage of the head capsule, between the cuticle of the insect mandible and the cuticle of the labium, composed of cuticle of cardo, which is attached to the cuticle of stipes by the cardo-stipital conjunctiva; the cuticle of stipes, which is attached to the cuticle of galea by the stipito-galeal conjunctiva, to the cuticle of lacinia by the stipito-lacinial conjunctiva, and to the cuticle of palpifer by the stipito-palpiferal conjunctiva; the cuticle of palpifer is attached to the cuticle of maxillary palpus by the palpifero-palpal conjunctiva." [] {term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000165 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! mouthpart relationship: BFO:0000051 AISM:0000018 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part cardo relationship: BFO:0000051 AISM:0000023 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part galea relationship: BFO:0000051 AISM:0000026 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part lacinia relationship: BFO:0000051 AISM:0000051 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part maxillary palpus relationship: BFO:0000051 AISM:0000110 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part cardo-stipital conjunctiva relationship: BFO:0000051 AISM:0000111 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part stipes relationship: BFO:0000051 AISM:0004001 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part palpifer relationship: BFO:0000051 AISM:0004009 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part stipito-lacinial conjunctiva relationship: BFO:0000051 AISM:0004010 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part stipito-palpiferal conjunctiva relationship: BFO:0000051 AISM:0004011 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part stipito-galeal conjunctiva relationship: BFO:0000051 AISM:0004012 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part palpifero-palpal conjunctiva relationship: BSPO:0000096 AISM:0000087 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anterior to labium relationship: BSPO:0000099 AISM:0000043 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! posterior to insect mandible relationship: RO:0000053 PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has characteristic bilaterally paired relationship: RO:0002220 AISM:0000019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to head capsule property_value: IAO:0000589 "cuticle of insect maxilla" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000045 name: mesothoracic-metathoracic conjunctiva def: "The conjunctiva of the insect thorax that connects the mesothorax and the metathorax." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: BFO:0000050 AISM:0000108 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect thorax relationship: RO:0002150 AISM:0004126 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! continuous with mesothorax relationship: RO:0002150 AISM:0004127 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! continuous with metathorax [Term] id: AISM:0000046 name: prothoracic-mesothoracic conjunctiva def: "The conjunctiva of the insect thorax joining the prothorax and the mesothorax." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2020-03-18"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: BFO:0000050 AISM:0000108 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect thorax relationship: RO:0002150 AISM:0004125 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with prothorax relationship: RO:0002150 AISM:0004126 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with mesothorax [Term] id: AISM:0000047 name: distitarsus {AISM:0000171="Dashman, T. (1953) Terminology of the pretarsus. Annals of the Entomological Society of America 46, 56–62. https://doi.org/10.1093/aesa/46.1.56\n\n\"The distitarsus is the terminal, or most distal tarsal segment\"", IAO:0000232="Modified 2026-02-14: Updated to distitarsus to better reflect distal position on the leg.\n\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Pretarsus: apical element of leg bearing ungues; distinct and cylindrical in entognathous hexapods, strongly reduced in Insecta.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the appendage of the insect leg that is attached to the cuticle of tarsus by the tarso-distitarsal conjunctiva." [] {term:modified="2026-02-14", term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} synonym: "pretarsus" EXACT [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000029 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect appendage relationship: BFO:0000050 AISM:0000031 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect leg relationship: RO:0002150 AISM:0004187 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with tarso-distitarsal conjunctiva property_value: IAO:0000589 "cuticle of distitarsus" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000048 name: ligula {AISM:0000171="Snodgrass RE (1993) Principles of Insect Morphology. Cornell University Press, 768 pp.\n\nhttps://www.jstor.org/stable/10.7591/j.ctv1nhm1j\n\n\"Ligula - The terminal lobes of the labium collectively, or a terminal part of the labium formed by the union of the lobes.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the appendage of the cuticle of labium composed of the cuticle of glossa and cuticle of paraglossa jointly." [] {term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000029 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect appendage relationship: BFO:0000050 AISM:0000087 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! part of labium relationship: BFO:0000051 AISM:0000049 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part glossa relationship: BFO:0000051 AISM:0000050 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part paraglossa property_value: IAO:0000589 "cuticle of ligula" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000049 name: glossa {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Glossa: paired inner endite lobes of the prementum.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the appendage of the labium, and part of the ligula, that is attached to the prementum by the premental-glossal conjunctiva." [] {term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000029 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect appendage relationship: BFO:0000050 AISM:0000048 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! part of ligula relationship: RO:0002150 AISM:0004016 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with premental-glossal conjunctiva relationship: RO:0002220 AISM:0000057 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to prementum property_value: IAO:0000589 "cuticle of glossa" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000050 name: paraglossa {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Paraglossa: paired outer endite lobes of the prementum (labium).\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the paired appendage of the labium, and part of the ligula, that is attached to the cuticle of prementum by the premental-paraglossal conjunctiva." [] {term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000029 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect appendage relationship: BFO:0000050 AISM:0000048 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of ligula relationship: RO:0002150 AISM:0004015 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with premental-paraglossal conjunctiva relationship: RO:0002220 AISM:0000057 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to prementum property_value: IAO:0000589 "cuticle of paraglossa" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000051 name: maxillary palpus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043\n\n\"Palp: tactile appendage of maxilla\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the appendage of the insect maxilla that is attached to the cuticle of palpifer by the palpifero-palpal conjunctiva." [] {term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000029 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect appendage relationship: AISM:0000079 AISM:0004012 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by palpifero-palpal conjunctiva relationship: BFO:0000050 AISM:0000044 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect maxilla relationship: BFO:0000051 AISM:0002036 {creation_date="2023-04-13"} ! has part maxillary palpomere relationship: RO:0000053 PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has characteristic bilaterally paired relationship: RO:0002220 AISM:0000019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to head capsule relationship: RO:0002220 AISM:0004001 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to palpifer property_value: IAO:0000589 "cuticle of maxillary palpus" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000052 name: mesonotum def: "The notum or sclerite on the dorsal region of the mesothorax that is posterior to the pronotum, connected via the mesonoto-mesopleural conjuntiva to the dorsal margin of the mesopleuron, that is not adjacent to the mesocoxa, but attached to it by the mesocoxal muscle." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000003 {x_1.1:contributor="jcgiron"} ! insect sclerite is_a: AISM:0004128 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! notum is_a: UBERON:0000061 ! anatomical structure relationship: BSPO:0000099 AISM:0000059 {x_1.1:contributor="jcgiron"} ! posterior to pronotum relationship: RO:0002150 AISM:0004219 {x_1.1:contributor="jcgiron"} ! continuous with mesonoto-mesopleural conjuntiva relationship: RO:0002371 AISM:0000085 {x_1.1:contributor="jcgiron"} ! attached to mesocoxal muscle [Term] id: AISM:0000053 name: mesopectus {creation_date="2020-11-11"} def: "The sclerite that is continuous with the basal mesocoxal conjunctiva and the basal wing conjunctiva and contains the mesofurca." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"} is_a: AISM:0000003 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite relationship: BFO:0000051 AISM:0000141 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! has part mesofurca relationship: RO:0002150 AISM:0000103 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! continuous with basal mesocoxal conjunctiva relationship: RO:0002150 AISM:0004203 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! continuous with basal wing conjunctiva [Term] id: AISM:0000054 name: mesotrochantin {creation_date="2020-11-11"} def: "The trochantin that is located on the ventro-lateral region of the mesothorax and is attached to a mesocoxa and surrounded by the basal mesocoxal conjunctiva." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004135 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! trochantin relationship: AISM:0000079 AISM:0000103 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by basal mesocoxal conjunctiva relationship: RO:0002220 AISM:0000064 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to mesocoxa [Term] id: AISM:0000055 name: protrochantin {creation_date="2020-11-11"} def: "The trochantin that is located on the ventro-lateral region of the prothorax and is attached to a procoxa and surrounded by the basal procoxal conjunctiva." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004135 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! trochantin relationship: AISM:0000079 AISM:0000106 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by basal procoxal conjunctiva relationship: RO:0002220 AISM:0000066 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to procoxa [Term] id: AISM:0000056 name: metatrochantin {creation_date="2020-11-11"} def: "The trochantin that is located on the ventro-lateral region of the metathorax and is attached to a metacoxa and surrounded by the basal metacoxal conjunctiva." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004135 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! trochantin relationship: AISM:0000079 AISM:0000104 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by basal metacoxal conjunctiva relationship: RO:0002220 AISM:0000065 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to metacoxa [Term] id: AISM:0000057 name: prementum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Prementum: distal main element of labium, bearing the endite lobes (glossa and paraglossa) and the labial palp.\""} def: "The sclerite of the labium that is connected to the mentum by the mental-premental conjunctiva, to the palpiger by the premental-palpigeral conjunctiva, to the paraglossa by the premental-paraglossal conjunctiva, and to the glossa by the premental-glossal conjunctiva." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000003 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite relationship: BFO:0000050 AISM:0000087 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of labium relationship: RO:0002150 AISM:0004002 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with mental-premental conjunctiva relationship: RO:0002150 AISM:0004014 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with premental-palpigeral conjunctiva relationship: RO:0002150 AISM:0004015 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with premental-paraglossal conjunctiva relationship: RO:0002150 AISM:0004016 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with premental-glossal conjunctiva relationship: RO:0002220 AISM:0000049 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to glossa relationship: RO:0002220 AISM:0000050 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to paraglossa relationship: RO:0002220 AISM:0004004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to insect mentum relationship: RO:0002220 AISM:0004006 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to palpiger [Term] id: AISM:0000058 name: prepectus {creation_date="2020-11-11"} def: "The sclerite that is posterior to the pronotum and receives the site of attachment of the dilutor muscle of the first thoracic spiracle." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"} is_a: AISM:0000003 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite is_a: UBERON:0000061 ! anatomical structure [Term] id: AISM:0000059 name: pronotum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Pronotum: prothoracic tergum.\""} def: "The notum or sclerite on the dorsal region of the prothorax that is attached to cranial muscles, procoxal muscles, contiuous posterioirly with the neck membrane and with pronoto-propleural conjunctiva and not adjacent (not touching) to the procoxa." [] {term:modified="2022-03-09", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-03-18"} is_a: AISM:0000003 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite is_a: AISM:0004128 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! notum is_a: UBERON:0000061 ! anatomical structure relationship: anteriorly_connected_to AISM:0000098 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! neck membrane relationship: RO:0002150 AISM:0004220 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! continuous with pronoto-propleural conjunctiva relationship: RO:0002371 AISM:0000080 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! attached to insect cranial muscle relationship: RO:0002371 AISM:0000145 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! attached to procoxal muscle [Term] id: AISM:0000060 name: labial palpomere {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the mere that is part of the labial palpus." [] {term:modified="2021-12-08", creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000073 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mere relationship: BFO:0000050 AISM:0000024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of labial palpus property_value: IAO:0000589 "cuticle of labial palpomere" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000061 name: prosternum def: "The sclerite on the ventral region of the prothorax that bears the profurca and is attached to the propleuro-prosternal conjunctiva." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0004130 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! sternum relationship: BFO:0000051 AISM:0000143 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! has part profurca relationship: RO:0002150 AISM:0004202 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! continuous with propleuro-prosternal conjunctiva [Term] id: AISM:0000062 name: ring sclerite def: "The sclerite that is cylindrical and encircles and is encircled by conjunctiva." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"} is_a: AISM:0000003 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite relationship: AISM:0000078 AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircles conjunctiva relationship: AISM:0000079 AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by conjunctiva relationship: RO:0000053 PATO:0001873 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has characteristic cylindrical [Term] id: AISM:0000063 name: appendage segment {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The ring sclerite that is part of an appendage and is attached to muscle." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"} is_a: AISM:0000062 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! ring sclerite relationship: BFO:0000050 AISM:0000029 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! part of insect appendage relationship: RO:0002150 UBERON:0014895 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! continuous with somatic muscle, invertebrate property_value: IAO:0000589 "cuticle of appendage segment" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000064 name: mesocoxa {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of the mid leg that is attached to the latero-ventral region of the mesothorax by the basal mesocoxal conjunctiva." [] {term:modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0000077 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coxa relationship: AISM:0000079 AISM:0000103 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by basal mesocoxal conjunctiva relationship: BFO:0000050 AISM:0000035 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of mid leg property_value: IAO:0000589 "cuticle of mesocoxa" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000065 name: metacoxa {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of the hind leg that is attached to the latero-ventral region of the metathorax by the basal metacoxal conjunctiva." [] {term:modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0000077 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coxa relationship: AISM:0000079 AISM:0000104 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by basal metacoxal conjunctiva relationship: BFO:0000050 AISM:0000036 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of hind leg property_value: IAO:0000589 "cuticle of metacoxa" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000066 name: procoxa {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of the fore leg that is attached to the latero-ventral region of the prothorax by the basal procoxal conjunctiva." [] {term:modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0000077 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coxa relationship: AISM:0000079 AISM:0000106 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by basal procoxal conjunctiva relationship: BFO:0000050 AISM:0000034 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of fore leg property_value: IAO:0000589 "cuticle of procoxa" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000067 name: protibia {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of a fore leg attached to the distal margin of the profemur by the profemoro-protibial conjunctiva." [] {creation_date="2021-04-03", term:modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000075 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tibia relationship: AISM:0000079 AISM:0004179 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by profemoro-protibial conjunctiva relationship: BFO:0000050 AISM:0000034 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of fore leg property_value: IAO:0000589 "cuticle of protibia" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000068 name: mesotibia {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of a mid leg attached to the distal margin of the mesofemur by the mesofemoro-mesotibial conjunctiva." [] {creation_date="2021-04-03", term:modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000075 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tibia relationship: AISM:0000079 AISM:0004180 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by mesofemoro-mesotibial conjunctiva relationship: BFO:0000050 AISM:0000035 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of mid leg property_value: IAO:0000589 "cuticle of mesotibia" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000069 name: metatibia {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of a hind leg attached to the distal margin of the metafemur by the metafemoro-metatibial conjunctiva." [] {creation_date="2021-04-03", term:modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000075 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tibia relationship: AISM:0000079 AISM:0004181 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by metafemoro-metatibial conjunctiva relationship: BFO:0000050 AISM:0000036 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of hind leg property_value: IAO:0000589 "cuticle of metatibia" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000070 name: profemur {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of a fore leg attached to the distal margin of the protrochanter by the protrochantero-profemoral conjunctiva." [] {term:modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0000076 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! femur relationship: AISM:0000079 AISM:0000123 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by procoxal-protrochanteral conjunctiva relationship: BFO:0000050 AISM:0000034 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of fore leg property_value: IAO:0000589 "cuticle of profemur" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000071 name: mesofemur {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of a mid leg attached to the distal margin of the mesotrochanter by the mesotrochantero-mesofemoral conjunctiva." [] {term:modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0000076 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! femur relationship: AISM:0000079 AISM:0000124 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by mesocoxal-mesotrochanteral conjunctiva relationship: BFO:0000050 AISM:0000035 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of mid leg property_value: IAO:0000589 "cuticle of mesofemur" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000072 name: metafemur {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of a hind leg attached to the distal margin of the metatrochanter by the metatrochantero-metafemoral conjunctiva." [] {term:modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0000076 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! femur relationship: AISM:0000079 AISM:0000125 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by metacoxal-metatrochanteral conjunctiva relationship: BFO:0000050 AISM:0000036 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of hind leg property_value: IAO:0000589 "cuticle of metafemur" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000073 name: mere {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The ring sclerite that is part of an appendage and is not attached to somatic muscle." [] {term:modified="2021-12-08", creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000062 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! ring sclerite relationship: BFO:0000050 AISM:0000029 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! part of insect appendage property_value: IAO:0000589 "cuticle of mere" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000074 name: tarsomere {AISM:0000171="\"Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Tarsomere: subelement of tarsus in Insecta; number often taxon-specific, sometimes differing on legs of different segments (diagnostic value: tarsal formula).\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the mere that is part of the tarsus." [] {term:modified="2021-12-08", creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000073 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! mere relationship: BFO:0000050 AISM:0004169 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of tarsus property_value: IAO:0000589 "cuticle of tarsomere" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000075 name: tibia {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Tibia: 4th element of leg; usually cylindrical and equipped with paired terminal spurs, often with rows of spines.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of a leg attached to the distal margin of the femur by the femoro-tibial conjunctiva." [] {creation_date="2021-04-03", term:modified="2021-12-08", comment="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000063 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! appendage segment relationship: AISM:0000079 AISM:0004178 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by femoro-tibial conjunctiva relationship: BFO:0000050 AISM:0000031 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect leg relationship: RO:0000053 PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has characteristic bilaterally paired property_value: IAO:0000589 "cuticle of tibia" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000076 name: femur {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Femur: 3rd element of leg, often largest part.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of a leg attached to the distal margin of the trochanter by the trochantero-femoral conjunctiva." [] {term:modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0000063 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! appendage segment relationship: AISM:0000079 AISM:0004174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by trochantero-femoral conjunctiva relationship: BFO:0000050 AISM:0000031 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect leg relationship: RO:0000053 PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has characteristic bilaterally paired property_value: IAO:0000589 "cuticle of femur" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000077 name: coxa {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Coxa: basal element of leg; articulated with pleural, sternal and usually also trochantinal elements of thoracic segment.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of the leg that is attached to the latero-ventral region of the insect thorax by the basal coxal conjunctiva." [] {term:modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0000063 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! appendage segment relationship: AISM:0000079 AISM:0000173 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by basal coxal conjunctiva relationship: BFO:0000050 AISM:0000031 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect leg relationship: RO:0000053 PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has characteristic bilaterally paired property_value: IAO:0000589 "cuticle of coxa" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000080 name: insect cranial muscle def: "The somatic muscle that is attached to the head capsule." [] {creation_date="2021-04-04", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: UBERON:0014895 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932", term:modified="2021-12-13"} ! somatic muscle, invertebrate relationship: RO:0002371 AISM:0000019 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to head capsule [Term] id: AISM:0000081 name: cranio-antennal muscle def: "The somatic muscle that is attached to the head capsule and the antenna." [] {creation_date="2021-04-04", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932", term:modified="2021-12-13"} is_a: AISM:0000080 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranial muscle relationship: RO:0002371 AISM:0000032 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to antenna [Term] id: AISM:0000082 name: cranio-mandibular muscle def: "The somatic muscle that is attached to the head capsule and the insect mandible." [] {creation_date="2021-04-04", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932", term:modified="2021-12-13"} is_a: AISM:0000080 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect cranial muscle relationship: RO:0002371 AISM:0000043 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to insect mandible [Term] id: AISM:0000083 name: cranio-labial muscle def: "The somatic muscle that is attached to the head capsule and the labium." [] {creation_date="2021-04-04", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000080 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranial muscle relationship: RO:0002371 AISM:0000087 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to labium [Term] id: AISM:0000084 name: cranio-labral muscle def: "The somatic muscle that is attached to the head capsule and the labrum." [] {creation_date="2021-04-04", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932", term:modified="2021-12-13"} is_a: AISM:0000080 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranial muscle relationship: RO:0002371 AISM:0000042 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to labrum [Term] id: AISM:0000085 name: mesocoxal muscle {creation_date="2020-11-11"} def: "The coxal muscle of the mesocoxa." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000086 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coxal muscle relationship: RO:0002371 AISM:0000064 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! attached to mesocoxa [Term] id: AISM:0000086 name: coxal muscle def: "The somatic muscle that inserts in the coxa." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21", term:modified="2021-12-13"} is_a: AISM:0002064 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect leg muscle relationship: RO:0002371 AISM:0000077 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! attached to coxa property_value: IAO:0000232 "All of the coxal muscles, except the second sternal-metacoxal muscle, are attached to the thorax." xsd:string {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} [Term] id: AISM:0000087 name: labium {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"The labium or lower lip forms the posterior (orthognathous head) or ventral (prognathous head) closure of the preoral space and of the salivarium. It is homologous to the maxilla (2nd maxilla) of crustaceans, but its proximal\nparts form a structural unit without a recognizable median line or suture.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the mouthpart appendage composed of the cuticle of submentum, which is attached by the submental-mental conjunctiva to the cuticle of mentum, which is attached by the mental-premental conjunctiva to the cuticle of prementum, which is attached to the cuticle of palpiger by the premental-palpigeral conjunctiva, the cuticle of paraglossa by the premental-paraglossal conjunctiva, and the cuticle of glossa by the premental-glossal conjunctiva; the cuticle of palpiger is attached by the palpigero-palpal conjunctiva to the cuticle of labial palpus." [] {term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000165 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! mouthpart relationship: BFO:0000051 AISM:0000024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part labial palpus relationship: BFO:0000051 AISM:0000048 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part ligula relationship: BFO:0000051 AISM:0000057 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part prementum relationship: BFO:0000051 AISM:0004002 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part mental-premental conjunctiva relationship: BFO:0000051 AISM:0004004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part insect mentum relationship: BFO:0000051 AISM:0004005 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part submentum relationship: BFO:0000051 AISM:0004006 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part palpiger relationship: BFO:0000051 AISM:0004013 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part submental-mental conjunctiva relationship: BFO:0000051 AISM:0004014 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part premental-palpigeral conjunctiva relationship: BFO:0000051 AISM:0004015 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part premental-paraglossal conjunctiva relationship: BFO:0000051 AISM:0004016 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part premental-glossal conjunctiva relationship: BFO:0000051 AISM:0004017 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part palpigero-palpal conjunctiva property_value: IAO:0000589 "cuticle of labium" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000088 name: eye cuticle {creation_date="2020-11-11"} def: "The elastic cuticle of the head capsule that is transparent and covers the eye." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000007 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! elastic cuticle relationship: BFO:0000050 AISM:0000019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of head capsule relationship: RO:0000053 PATO:0000964 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! has characteristic transparent [Term] id: AISM:0000089 name: insect ligament {creation_date="2020-11-11", IAO:0000232="Modified 2023-01-09 to specify insect ligament.\njgiron https://orcid.org/0000-0002-0851-6883"} def: "The resilin rich region that connects two sclerites." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"} is_a: AISM:0000007 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! elastic cuticle relationship: BFO:0000050 AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! part of conjunctiva relationship: RO:0002150 AISM:0000003 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! continuous with insect sclerite [Term] id: AISM:0000090 name: cuticular tendon {AISM:0000171="Klass K-D (2001) The female abdomen of the viviparous earwig Hemimerus vosseleri (Insecta: Dermaptera: Hemimeridae), with a discussion of the postgenital abdomen of Insecta. Zoological Journal of the Linnean Society 131: 251–307. \n\nhttps://doi.org/10.1111/j.1096-3642.2001.tb02239.x \n\n\"tendon is used herein to designate membranous internal cuticular projections\""} def: "The apodeme of elastic cuticle that is continuous with somatic muscle." [] {x_1.1:contributor="2022-06-22", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000007 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! elastic cuticle is_a: AISM:0000188 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! apodeme relationship: RO:0002150 UBERON:0014895 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! continuous with somatic muscle, invertebrate property_value: IAO:0000232 "The usually cylindircal evagination of the cuticle that is resilin rich and is continuous with somatic muscles." xsd:string {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-11-11"} [Term] id: AISM:0000091 name: insect trachea {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Trachea: tube-shaped elements of the tracheal system.\"", IAO:0000232="Modified 2023-01-09 to specify insect trachea.\njgiron https://orcid.org/0000-0002-0851-6883"} def: "The branching invagination of elastic cuticle that is cylindrical and contains taenidia." [] {creation_date="2020-11-11", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000007 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! elastic cuticle is_a: AISM:0000136 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! branching cuticular invagination relationship: BFO:0000051 AISM:0000140 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! has part taenidium relationship: RO:0000053 PATO:0001873 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! has characteristic cylindrical [Term] id: AISM:0000093 name: hypopharynx {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Hypopharynx: median unpaired lobe between mouthparts and epipharynx; anterior (dorsal) surface continuous with anterior pharynx.\""} def: "The conjunctiva of the insect head that is attached to the salivarium and to the oral foraminal conjunctiva." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: BFO:0000050 AISM:0000107 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect head relationship: RO:0002150 AISM:0000099 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with oral foraminal conjunctiva relationship: RO:0002150 AISM:0000159 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with salivarium [Term] id: AISM:0000094 name: mesopleuro-metapleural conjunctiva def: "The conjunctiva of the insect thorax that joins the mesopleuron and the metapleuron." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: BFO:0000050 AISM:0000108 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect thorax relationship: RO:0002150 AISM:0000119 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with metapleuron relationship: RO:0002150 AISM:0004186 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with mesopleuron [Term] id: AISM:0000095 name: metasterno-metacoxal conjunctiva def: "The conjunctiva of the mesothorax that joins the metasternum and the metacoxa." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: BFO:0000050 AISM:0004127 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of metathorax relationship: RO:0002150 AISM:0000065 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with metacoxa relationship: RO:0002150 AISM:0004232 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with metasternum [Term] id: AISM:0000096 name: prosternal-procoxal conjunctiva def: "The conjunctiva of the prothorax that joins the prosternum and the procoxa." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: BFO:0000050 AISM:0004125 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of prothorax relationship: RO:0002150 AISM:0000061 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with prosternum relationship: RO:0002150 AISM:0000066 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with procoxa [Term] id: AISM:0000097 name: metapleuro-metacoxal conjunctiva def: "The conjunctiva of the metathorax that joins the metapleuron and the metacoxa." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: BFO:0000050 AISM:0004127 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of metathorax relationship: RO:0002150 AISM:0000065 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with metacoxa relationship: RO:0002150 AISM:0000119 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with metapleuron [Term] id: AISM:0000098 name: neck membrane def: "The conjuctiva that is continuous with the posterior margin of the head capsule and with the anterior margin of the prothorax, and bears cervical sclerites." [] {creation_date="2020-11-11", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", term:modified="2022-06-27"} synonym: "cervical membrane" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Cervical membrane: membrane connecting the head and prothorax.\""} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: AISM:0000078 AISM:0004141 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles cervical sclerite [Term] id: AISM:0000099 name: oral foraminal conjunctiva def: "The conjunctiva of the insect head that connects the head capsule and the mouthparts." [] {creation_date="2021-04-03", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: BFO:0000050 AISM:0000107 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect head relationship: RO:0002220 AISM:0000019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to head capsule relationship: RO:0002220 AISM:0000165 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to mouthpart [Term] id: AISM:0000100 name: pronoto-mesonotal conjunctiva def: "The conjunctiva of the insect thorax that joins the pronotum and the mesonotum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: BFO:0000050 AISM:0000108 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect thorax relationship: RO:0002150 AISM:0000052 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with mesonotum relationship: RO:0002150 AISM:0000059 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with pronotum [Term] id: AISM:0000101 name: pronoto-mesopectal conjunctiva def: "The conjunctiva that is attached to the pronotum and the mesopectus." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: RO:0002150 AISM:0000053 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with mesopectus relationship: RO:0002150 AISM:0000059 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with pronotum [Term] id: AISM:0000102 name: ring conjunctiva def: "The conjunctiva that encircles a ring sclerite." [] {creation_date="2021-04-03", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: AISM:0000078 AISM:0000062 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircles ring sclerite [Term] id: AISM:0000103 name: basal mesocoxal conjunctiva def: "The conjunctiva that encircles the mesocoxa and connects it to the ventral and lateral regions of the mesothorax." [] {creation_date="2020-11-11", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000173 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! basal coxal conjunctiva relationship: RO:0002150 AISM:0004126 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with mesothorax [Term] id: AISM:0000104 name: basal metacoxal conjunctiva def: "The conjunctiva that encircles the metacoxa and connects it to the ventral and lateral regions of the metathorax." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0000173 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! basal coxal conjunctiva relationship: RO:0002150 AISM:0004127 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with metathorax [Term] id: AISM:0000105 name: epipharynx {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Epipharynx: semimembranous or membranous posterior wall of labrum and roof of cibarium.\""} def: "The conjunctiva of the insect head that is connected to the oral foraminal conjunctiva and to the distal margin of the labrum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: BFO:0000050 AISM:0000107 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect head relationship: RO:0002150 AISM:0000099 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! continuous with oral foraminal conjunctiva [Term] id: AISM:0000106 name: basal procoxal conjunctiva def: "The conjunctiva that encircles the procoxa and connects it to the ventral and lateral regions of the prothorax." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0000173 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! basal coxal conjunctiva relationship: RO:0002150 AISM:0004125 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with prothorax [Term] id: AISM:0000107 name: insect head {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"The head is a compact and complex tagma with a concentration of a broad array of structures und functions. It is equipped with sense organs such as the highly complex compound eyes and the antennae, an elaborate set of mouthparts, and a complex muscle apparatus. It also contains central elements of the nervous system, the anterior part of the digestive tract including the cibarium (preoral cavity) and the salivarium, and also neurohaemal organs.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticular region that is anterior (distal) to the neck membrane (encircled by the neck membrane) and contains the head capsule, the antenna, the eyes, mouthparts and surrounds the brain." [] {creation_date="2020-11-11", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000174 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect region of cuticle is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:6007289 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect tagmatic subdivision of integument intersection_of: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! insect region of cuticle intersection_of: UBERON:6007289 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! insect tagmatic subdivision of integument intersection_of: BFO:0000051 AISM:0000019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! has part head capsule intersection_of: BSPO:0000096 AISM:0000098 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! anterior to neck membrane relationship: AISM:0000079 AISM:0000098 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by neck membrane relationship: BFO:0000051 AISM:0000019 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! has part head capsule relationship: BFO:0000051 AISM:0000032 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! has part antenna relationship: BFO:0000051 AISM:0000093 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part hypopharynx relationship: BFO:0000051 AISM:0000099 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part oral foraminal conjunctiva relationship: BFO:0000051 AISM:0000105 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part epipharynx relationship: BFO:0000051 AISM:0000112 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! has part cranio-antennal conjunctiva relationship: BFO:0000051 AISM:0000165 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part mouthpart relationship: BSPO:0000096 AISM:0000098 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! anterior to neck membrane relationship: RO:0002221 UBERON:0000955 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! surrounds brain property_value: IAO:0000589 "cuticle of insect head" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000108 name: insect thorax {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The region of cuticle that is connected to some muscles of the fore and hind legs and is posterior to the neck membrane and aterior to the first abdominal spiracle." [] {creation_date="2020-11-11", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000174 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect region of cuticle is_a: UBERON:6007289 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect tagmatic subdivision of integument intersection_of: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! insect region of cuticle intersection_of: UBERON:6007289 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! insect tagmatic subdivision of integument intersection_of: BSPO:0000096 AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! anterior to insect abdomen intersection_of: BSPO:0000099 AISM:0000098 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! posterior to neck membrane relationship: BFO:0000051 AISM:0000085 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! has part mesocoxal muscle relationship: BFO:0000051 AISM:0000145 ! has part procoxal muscle relationship: BFO:0000051 AISM:0004125 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part prothorax relationship: BFO:0000051 AISM:0004126 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part mesothorax relationship: BFO:0000051 AISM:0004127 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part metathorax relationship: BSPO:0000096 AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anterior to insect abdomen relationship: BSPO:0000099 AISM:0000098 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! posterior to neck membrane property_value: IAO:0000232 "The hind leg muscles sometimes attach to the second abdominal sternite. The abdominal sopiracles are different in their structure from tghe thoracic spiracles as they are opened and closed by two articulating sclerites that are moved by two sets of muscles whereas the thoracic spiracles are closed by only one occlusor muscle and opened by the flexibility of the distal tracheal region. The border between the thorax and the abdomen is sometimes marked by the anterior first abdmonial tergal conjunctiva. In Hymenoptera, the border between the abdomen and the thorax cannot be defined as the anterior first abdmonial tergal conjunctiva is absent, the sclerite that receives muscles from the metacoxa also contains the first abdominal spiracle." xsd:string {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-11-11"} property_value: IAO:0000589 "cuticle of insect thorax" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000109 name: insect abdomen {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The region of the cuticle that is an insect tagmatic subdivision of the integument, posterior to the thorax." [] {creation_date="2020-11-11", IAO:0000232="Modified 2024-01-25: added 'insect tagmatic subdivision of integument'.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000174 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect region of cuticle is_a: UBERON:6007289 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect tagmatic subdivision of integument intersection_of: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! insect region of cuticle intersection_of: UBERON:6007289 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! insect tagmatic subdivision of integument intersection_of: BSPO:0000099 AISM:0000108 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! posterior to insect thorax relationship: BFO:0000051 AISM:0004055 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part preabdomen relationship: BFO:0000051 AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part postabdomen relationship: BSPO:0000099 AISM:0000108 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! posterior to insect thorax property_value: IAO:0000232 "The thorax is defined based on local properties (e.g. attachment sites of coxal muscles) and therefore we can reference this class for the definition of the abdomen." xsd:string {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-11-11"} property_value: IAO:0000589 "cuticle of insect abdomen" xsd:string {comment="2023-04-13"} property_value: x_0.1:depiction https://ndownloader.figshare.com/files/6014256/preview/6014256/preview.jpg [Term] id: AISM:0000110 name: cardo-stipital conjunctiva def: "The conjunctiva of the insect maxilla that connects the cardo and the stipes." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: BFO:0000050 AISM:0000044 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect maxilla relationship: RO:0002150 AISM:0000018 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! continuous with cardo relationship: RO:0002150 AISM:0000111 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with stipes [Term] id: AISM:0000111 name: stipes {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Stipes: second element of maxilla, connected with cardo by a hinge; bearing endite lobes (galea and lacinia) and maxillary palp.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the sclerite of the insect maxilla that is attached to the cuticle of cardo by the cardo-stipital conjunctiva, attached to the cuticle of lacinia by the stipito-lacinial conjunctiva, attached to the cuticle of palpifer by the stipito-palpiferal conjunctiva, and attached to the cuticle of galea by the stipito-galeal conjunctiva." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000003 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite relationship: BFO:0000050 AISM:0000044 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect maxilla relationship: RO:0002150 AISM:0000110 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! continuous with cardo-stipital conjunctiva relationship: RO:0002150 AISM:0004009 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with stipito-lacinial conjunctiva relationship: RO:0002150 AISM:0004010 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with stipito-palpiferal conjunctiva relationship: RO:0002150 AISM:0004011 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with stipito-galeal conjunctiva relationship: RO:0002220 AISM:0000018 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to cardo relationship: RO:0002220 AISM:0000023 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to galea relationship: RO:0002220 AISM:0000026 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to lacinia relationship: RO:0002220 AISM:0004001 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to palpifer property_value: IAO:0000589 "cuticle of stipes" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000112 name: cranio-antennal conjunctiva def: "The conjunctiva that encircles the base of the antenna (scape) and is encircled by the head capsule as the antennal foramen." [] {creation_date="2020-11-11", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: AISM:0000078 AISM:0000113 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircles scapus relationship: AISM:0000079 AISM:0000019 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by head capsule [Term] id: AISM:0000113 name: scapus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\nScapus: basal element of antenna, with two muscles attached to the pedicellus.", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of the antenna that is connected to the head capsule and the antennifer by the basal antennal conjunctiva." [] {term:modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} synonym: "antennomere 1" EXACT [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000063 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! appendage segment is_a: AISM:0004266 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! antennomere relationship: RO:0002150 AISM:0000112 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with cranio-antennal conjunctiva relationship: RO:0002220 AISM:0000019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to head capsule relationship: RO:0002220 AISM:0000190 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to antennifer property_value: IAO:0000589 "cuticle of scapus" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000114 name: scapal-pedicellar conjunctiva def: "The conjunctiva of the antenna that connects the scapus and the pedicellus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000102 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! ring conjunctiva relationship: AISM:0000078 AISM:0000115 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles pedicellus relationship: AISM:0000079 AISM:0000113 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by scapus relationship: BFO:0000050 AISM:0000032 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of antenna [Term] id: AISM:0000115 name: pedicellus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Pedicellus: second antennal segment in Insecta; contains Johnston’s organ and lacks intrinsic muscles.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of the antenna that is attached to the scapus by the scapal-pedicellar conjunctiva." [] {term:modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} synonym: "antennomere 2" EXACT [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000063 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! appendage segment is_a: AISM:0004266 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! antennomere relationship: AISM:0000079 AISM:0000114 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by scapal-pedicellar conjunctiva property_value: IAO:0000589 "cuticle of pedicellus" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000116 name: flagellomere {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the mere that is part of the antenna." [] {term:modified="2021-12-08", creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004266 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! antennomere relationship: BSPO:0000097 AISM:0000115 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! distal to pedicellus property_value: IAO:0000232 "Given the high number of flagellomeres occurring in some taxa, Arabic numerals are used instead of Roman numerals for practicality reasons." xsd:string {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} property_value: IAO:0000589 "cuticle of flagellomere" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000117 name: flagellomere 1 {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Flagellomere: segment of the flagellum.\"", IAO:0000232="Modified 2023-05-05: \"first\" replaced with \"1\"\ngmontanaro https://orcid.org/0000-0003-0836-1364", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the first flagellomere of the antenna, attached to the pedicel by the pedicel-first flagellomere conjunctiva." [] {term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} synonym: "antennomere 3" EXACT [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000116 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! flagellomere relationship: AISM:0000079 AISM:0000118 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by pedicellar-first flagellomeral conjunctiva property_value: IAO:0000589 "cuticle of first flagellomere" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000118 name: pedicellar-first flagellomeral conjunctiva def: "The conjunctiva of the antenna that connects the pedicellus and the first flagellomere." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: AISM:0000078 AISM:0000117 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircles flagellomere 1 relationship: AISM:0000079 AISM:0000115 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by pedicellus relationship: BFO:0000050 AISM:0000032 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of antenna [Term] id: AISM:0000119 name: metapleuron def: "The region of the cuticle on the lateral region of the metathorax that is attached to the metanotum and the metasternum, and is attached to the metacoxa by the metacoxal muscle and the basal metacoxal conjunctiva." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004129 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! pleuron relationship: RO:0002150 AISM:0000104 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! continuous with basal metacoxal conjunctiva relationship: RO:0002150 AISM:0000146 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with metacoxal muscle relationship: RO:0002220 AISM:0000169 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to metanotum relationship: RO:0002220 AISM:0004232 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to metasternum [Term] id: AISM:0000120 name: propleuro-procoxal conjunctiva def: "The conjunctiva of the prothorax that joins the propleuron and the procoxa." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: BFO:0000050 AISM:0004125 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of prothorax relationship: RO:0002150 AISM:0000066 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with procoxa relationship: RO:0002150 AISM:0004142 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with propleuron [Term] id: AISM:0000121 name: mesosternum def: "The sclerite on the ventral region of the mesothorax that bears the mesofurca and is attached to the mesopleuro-mesosternal conjunctiva." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0004130 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! sternum relationship: BFO:0000051 AISM:0000141 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part mesofurca relationship: RO:0002150 AISM:0004231 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with mesopleuro-mesosternal conjunctiva [Term] id: AISM:0000123 name: procoxal-protrochanteral conjunctiva def: "The conjunctiva of the fore leg joining the distal margin of a procoxa and the proximal margin of a protrochanter." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0004170 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! coxal-trochanteral conjunctiva relationship: BFO:0000050 AISM:0000034 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of fore leg [Term] id: AISM:0000124 name: mesocoxal-mesotrochanteral conjunctiva def: "The conjunctiva of the mid leg joining the distal margin of a mesocoxa and the proximal margin of a mesotrochanter." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0004170 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coxal-trochanteral conjunctiva relationship: BFO:0000050 AISM:0000035 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of mid leg [Term] id: AISM:0000125 name: metacoxal-metatrochanteral conjunctiva def: "The conjunctiva of the hind leg joining the distal margin of a metacoxa and the proximal margin of a metatrochanter." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0004170 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! coxal-trochanteral conjunctiva relationship: BFO:0000050 AISM:0000036 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of hind leg [Term] id: AISM:0000126 name: socket membrane {creation_date="2020-11-11"} def: "The conjunctiva that corresponds to one epithelial cell and surrounds a sclerotized unicellular cuticular evagination." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: RO:0002008 CL:0000066 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coincident with epithelial cell property_value: IAO:0000232 "Should coincide with 'exactly one' epithelial cell, but that violates OWL specs." xsd:string {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-26"} [Term] id: AISM:0000127 name: unicellular cuticular evagination def: "The cuticular evagination that corresponds to the evagination on the membrane of a single cell and not to the evagination of a cell layer." [] {creation_date="2020-11-11", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000027 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular evagination relationship: RO:0002008 CL:0000066 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coincident with epithelial cell property_value: IAO:0000232 "Should coincide with 'exactly one' epithelial cell, but that violates OWL specs." xsd:string {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-26"} [Term] id: AISM:0000128 name: multicellular cuticular evagination {creation_date="2020-11-11"} def: "The region of cuticle that corresponds to the evagination of the single layer epithelium." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"} is_a: AISM:0000027 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular evagination [Term] id: AISM:0000130 name: uniporous sensillum {IAO:0000232="Modified 2023-01-11: moved under cuticular sensilla; added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883"} def: "The seta that has one opening distally." [] {creation_date="2020-11-11", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0004304 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular sensilla relationship: BFO:0000051 AISM:0000039 {IAO:0000232="Modified 2023-01-11: added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! has part cuticular seta relationship: BFO:0000051 AISM:0000177 {IAO:0000232="Modified 2023-01-11: added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! has part pore canal property_value: IAO:0000232 "Should coincide with 'exactly one' pore canal, but that violates OWL specs." xsd:string {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-23"} [Term] id: AISM:0000131 name: multiporous sensillum {creation_date="2020-11-11", IAO:0000232="Modified 2023-01-11: moved under cuticular sensilla; added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Ando, T., Sekine, S., Inagaki, S., Misaki, K., Badel, L., Moriya, H., Sami, M.M., Itakura, Y., Chihara, T., Kazama, H. and Yonemura, S., 2019. Nanopore formation in the cuticle of an insect olfactory sensillum. Current Biology, 29(9), pp.1512-1520.\nhttps://www.sciencedirect.com/science/article/pii/S0960982219303410#fig4"} def: "The seta that has multiple cuticular pores (openings of class III exocrine glands)." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"} is_a: AISM:0004304 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular sensilla relationship: BFO:0000051 AISM:0000039 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! has part cuticular seta relationship: RO:0000053 PATO:0000984 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! has characteristic porous [Term] id: AISM:0000132 name: placoid sensillum {creation_date="2020-11-11"} def: "The multiporous plate that is elongated." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"} is_a: AISM:0000133 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! multiporous plate relationship: RO:0000053 PATO:0001154 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! has characteristic elongated [Term] id: AISM:0000133 name: multiporous plate {creation_date="2020-11-11"} def: "The multiporous sensillum that is flat." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"} is_a: AISM:0000131 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! multiporous sensillum relationship: RO:0000053 PATO:0000407 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! has characteristic flat [Term] id: AISM:0000134 name: cuticular exocrine gland duct {creation_date="2020-11-11", term:modified="2021-12-10"} def: "The branching cuticular invagination that corresponds to the invagination of the membrane of a single cell and does not contain taenidia." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"} is_a: AISM:0000136 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! branching cuticular invagination relationship: RO:0002008 CL:0000066 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coincident with epithelial cell property_value: IAO:0000232 "Should coincide with 'exactly one' epithelial cell, but that violates OWL specs." xsd:string {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-26"} [Term] id: AISM:0000135 name: insect spiracle {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Spiracle: external opening of the tracheal system.\"", term:modified="2023-01-09", IAO:0000232="Modified 2023-01-09: specifying insect spiracle.\njgiron https://orcid.org/0000-0002-0851-6883"} def: "The region of the cuticle that is continuous to the proximal region of a trachea and can be closed by muscles." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"} is_a: AISM:0000174 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect region of cuticle is_a: UBERON:0000061 ! anatomical structure relationship: RO:0002371 UBERON:0014895 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! attached to somatic muscle, invertebrate [Term] id: AISM:0000136 name: branching cuticular invagination def: "The cuticular ivagination that ramifies into umerous branches." [] {creation_date="2020-11-11", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000006 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular invagination relationship: RO:0000053 PATO:0000402 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! has characteristic branched property_value: IAO:0000232 "Branching cuticular invaginations porvide important models for branchig morphogenesis." xsd:string {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-11-11"} [Term] id: AISM:0000137 name: malphigian tube {creation_date="2020-11-11"} def: "The branching cuticular invagination that is located between the mid and hindgut." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"} xref: http://purl.obolibrary.org/obo/UBERON_0001054 is_a: AISM:0000136 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! branching cuticular invagination [Term] id: AISM:0000138 name: cuticular apophysis {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Apophysis: hollow cuticular invagination.\"", term:modified="2021-12-10"} def: "The cuticular invagination that is hollow." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"} is_a: AISM:0000006 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular invagination is_a: AISM:0000188 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! apodeme relationship: RO:0002008 AISM:0000193 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coincident with cuticular pit property_value: IAO:0000232 "The apophysis in HAO refers to an ivagination of the cuticle that is cylindrical as opposed to a ridge that is elongate. Beutel et al. 2014 differentiate apodemes from apophyses in that apodemes are solid and apophyses are hollow." xsd:string {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-11-11"} [Term] id: AISM:0000140 name: taenidium {creation_date="2020-11-11", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Taenidium: spiral-shaped strengthening ridge of the tracheae.\""} def: "The coiled ridge in the wall of the trachea." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"} is_a: AISM:0000158 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular ridge relationship: RO:0000053 PATO:0000404 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! has characteristic coiled [Term] id: AISM:0000141 name: mesofurca def: "The furca of the mesothorax that is attached to the mesocoxa via muscle." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000144 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! furca relationship: BFO:0000050 AISM:0004126 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of mesothorax [Term] id: AISM:0000142 name: metafurca def: "The furca of the metathorax that is attached to the metacoxa via muscle." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000144 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! furca relationship: BFO:0000050 AISM:0004127 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of metathorax [Term] id: AISM:0000143 name: profurca def: "The furca of the prothorax that is attached to the procoxa via muscle." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000144 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! furca relationship: BFO:0000050 AISM:0004125 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of prothorax [Term] id: AISM:0000144 name: furca {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Furca (=sternal apophysis, endosternite): endoskeletal element (entapophysis) of furcasternum; paired furcal arms often connected with pleural ridge by short muscle.\""} def: "The apophysis that is located ventromedially on the thorax and is connected to the coxa via muscles." [] {creation_date="2020-11-11", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} synonym: "endosternite" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Furca (=sternal apophysis, endosternite): endoskeletal element (entapophysis) of furcasternum; paired furcal arms often connected with pleural ridge by short muscle.\""} is_a: AISM:0000136 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! branching cuticular invagination is_a: AISM:0000138 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular apophysis is_a: UBERON:0000061 ! anatomical structure relationship: BFO:0000050 AISM:0000108 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! part of insect thorax relationship: BFO:0000050 BSPO:0000112 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! part of ventro-medial region [Term] id: AISM:0000145 name: procoxal muscle {creation_date="2020-11-11"} def: "The coxal muscle of the procoxa." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000086 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coxal muscle relationship: RO:0002371 AISM:0000066 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! attached to procoxa [Term] id: AISM:0000146 name: metacoxal muscle {creation_date="2020-11-11"} def: "The coxal muscle of the metacoxa." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000086 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coxal muscle relationship: RO:0002371 AISM:0000065 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! attached to metacoxa [Term] id: AISM:0000147 name: femoral muscle def: "The somatic muscle that inserts in the femur." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", term:modified="2021-12-13"} is_a: AISM:0002064 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect leg muscle relationship: RO:0002371 AISM:0000076 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! attached to femur [Term] id: AISM:0000148 name: tibial muscle def: "The somatic muscle that inserts in the tibia." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", term:modified="2021-12-13"} is_a: AISM:0002064 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect leg muscle relationship: RO:0002371 AISM:0000075 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! attached to tibia [Term] id: AISM:0000149 name: pretarsal muscle def: "The somatic muscle that inserts in the pretarsus." [] {creation_date="2020-11-11", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", term:modified="2021-12-13"} is_a: AISM:0002064 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect leg muscle relationship: RO:0002371 AISM:0000047 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! attached to distitarsus property_value: IAO:0000232 "There are usually two muscle bands of the pretarsal muscle, one is arising from the femur, the other from the tibia. The muscle usually inserts on a resilin rich basal sclerite of the pretarsus, the unguitractor plate." xsd:string {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-11-11"} [Term] id: AISM:0000150 name: profemoral muscle def: "The somatic muscle that inserts in the profemur." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", term:modified="2021-12-13"} is_a: AISM:0000147 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! femoral muscle relationship: RO:0002371 AISM:0000070 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! attached to profemur [Term] id: AISM:0000151 name: mesofemoral muscle def: "The somatic muscle that inserts in the mesofemur." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", term:modified="2021-12-13"} is_a: AISM:0000147 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! femoral muscle relationship: RO:0002371 AISM:0000071 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! attached to mesofemur [Term] id: AISM:0000152 name: metafemoral muscle def: "The somatic muscle that inserts in the metafemur." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", term:modified="2021-12-13"} is_a: AISM:0000147 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! femoral muscle relationship: RO:0002371 AISM:0000072 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! attached to metafemur [Term] id: AISM:0000153 name: protibial muscle def: "The somatic muscle that inserts in the protibia." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", term:modified="2021-12-13"} is_a: AISM:0000148 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! tibial muscle relationship: RO:0002371 AISM:0000067 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! attached to protibia [Term] id: AISM:0000154 name: mesotibial muscle def: "The somatic muscle that inserts in the mesotibia." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", term:modified="2021-12-13"} is_a: AISM:0000148 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! tibial muscle relationship: RO:0002371 AISM:0000068 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! attached to mesotibia [Term] id: AISM:0000155 name: metatibial muscle def: "The somatic muscle that inserts in the metatibia." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", term:modified="2021-12-13"} is_a: AISM:0000148 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! tibial muscle relationship: RO:0002371 AISM:0000069 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! attached to metatibia [Term] id: AISM:0000156 name: cuticular fovea {term:modified="2021-12-10"} def: "The cuticular depression that is circular." [] {creation_date="2020-11-11", IAO:0000232="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000005 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular depression relationship: RO:0000053 PATO:0000411 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! has characteristic circular [Term] id: AISM:0000157 name: cuticular groove {term:modified="2021-12-10", IAO:0000232="former 'impression'\nimiko https://orcid.org/0000-0003-2938-9075"} def: "The cuticular depression that is elongated and coincides with the distal side of an insect sclerite." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", IAO:0000232="Modified 2024-01-25: to reflect subclass of definiton\njgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000005 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular depression relationship: RO:0000053 PATO:0001154 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! has characteristic elongated property_value: IAO:0000232 "The cuticular depression (concavity on the surface of the cuticle) that does not correspond to a cuticular invagination (epithelial fold). The cuticule is less thick at the site of a cuticular impression." xsd:string {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-11-11"} [Term] id: AISM:0000158 name: cuticular ridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Ridge: cuticular strengthening ridge.\"\n\"They are not lines of fusion or molting lines.\"(p. 12)", term:modified="2021-12-10"} def: "The invagination on a sclerite that is elongated." [] {creation_date="2020-11-11", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000000 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular internal depression relationship: BFO:0000050 AISM:0000003 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! part of insect sclerite relationship: RO:0000053 PATO:0001154 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! has characteristic elongated [Term] id: AISM:0000159 name: salivarium {def="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Salivarium: posterior part of preoral space between hypopharynx and labium, with opening of salivary ducts.\""} def: "The conjunctiva in the head capsule that forms a pouch between the hypopharynx and the labium and bears the exocrine gland duct." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva is_a: AISM:0000160 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular pouch relationship: BFO:0000050 AISM:0000019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of head capsule relationship: RO:0002150 AISM:0000087 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! continuous with labium relationship: RO:0002150 AISM:0000093 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! continuous with hypopharynx relationship: RO:0002150 AISM:0000134 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! continuous with cuticular exocrine gland duct [Term] id: AISM:0000160 name: cuticular pouch {term:modified="2021-12-10"} def: "The invagination of the cuticle that is largely membranous." [] {creation_date="2020-11-12", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000006 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular invagination relationship: BFO:0000051 AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! has part conjunctiva [Term] id: AISM:0000161 name: discrimenal lamella def: "The ridge that is in the sagittal line of the ventro-medial region of the thorax." [] {creation_date="2020-11-12", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000158 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular ridge relationship: RO:0002008 BSPO:0000417 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coincident with sagittal plane [Term] id: AISM:0000162 name: cuticular sulcus {term:modified="2021-12-10"} def: "The cuticular depression (concavity on cuticle surface) that corresponds with a cuticular ridge (an elongate cuticular invagination)." [] {creation_date="2020-11-12", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", term:modified="2021-12-10"} is_a: AISM:0000157 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular groove relationship: RO:0002008 AISM:0000158 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coincident with cuticular ridge [Term] id: AISM:0000163 name: discrimen {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Discrimen: longitudinal ridge medially dividing the sternum\""} def: "The longitudinal (parallel to antero-posterior axis) sulcus that corresponds to the discrimenal lamella." [] {creation_date="2020-11-12", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000162 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular sulcus relationship: parallel_to BSPO:0000013 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anterior-posterior axis relationship: RO:0002150 AISM:0000161 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! continuous with discrimenal lamella [Term] id: AISM:0000165 name: mouthpart {creation_date="2020-11-17", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the appendage of the insect head that is encircled by the oral foraminal conjunctiva." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21", term:modified="2021-12-10"} is_a: AISM:0000029 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect appendage relationship: AISM:0000079 AISM:0000099 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by oral foraminal conjunctiva relationship: BFO:0000050 AISM:0000107 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect head property_value: IAO:0000589 "cuticle of mouthpart" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000166 name: propleuro-procoxal articulation def: "The insect articulation between the propleuron and the procoxa." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000002 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect articulation [Term] id: AISM:0000167 name: articular surface def: "The region of cuticle where two sclerites meet." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect region of cuticle relationship: RO:0002220 AISM:0000003 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! adjacent to insect sclerite [Term] id: AISM:0000168 name: salivary sclerite def: "The sclerite of the salivarium." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000003 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite relationship: BFO:0000050 AISM:0000159 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! part of salivarium [Term] id: AISM:0000169 name: metanotum def: "The notum or sclerite on the dorsal region of the metathorax that is posterior to the mesonotum, connected via the metanoto-metapleural conjuntiva to the dorsal margin of the metapleuron, that is not adjacent to the metacoxa, but attached to it by the metacoxal muscle." [] {x_1.1:contributor="jcgiron", creation_date="2021-04-21"} is_a: AISM:0000003 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite is_a: AISM:0004128 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! notum is_a: UBERON:0000061 ! anatomical structure relationship: BSPO:0000099 AISM:0000052 {x_1.1:contributor="jcgiron"} ! posterior to mesonotum relationship: RO:0002150 AISM:0004221 {x_1.1:contributor="jcgiron"} ! continuous with metanoto-metapleural conjunctiva relationship: RO:0002371 AISM:0000146 {x_1.1:contributor="jcgiron"} ! attached to metacoxal muscle [Term] id: AISM:0000170 name: metapectus def: "The sclerite that is continuous with the basal metacoxal conjunctiva and the basal wing conjunctiva and contains the metafurca." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"} is_a: AISM:0000003 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite relationship: BFO:0000051 AISM:0000142 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! has part metafurca relationship: RO:0002150 AISM:0000104 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! continuous with basal metacoxal conjunctiva relationship: RO:0002150 AISM:0004203 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! continuous with basal wing conjunctiva [Term] id: AISM:0000172 name: intertarsomeral conjunctiva def: "The conjunctiva is encircled by a tarsomere that encircles another tarsomere." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0000102 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! ring conjunctiva relationship: AISM:0000078 AISM:0000074 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles tarsomere relationship: AISM:0000079 AISM:0000074 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by tarsomere [Term] id: AISM:0000173 name: basal coxal conjunctiva def: "The conjunctiva that encircles the coxa and connects it to the ventral and lateral thoracic regions." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-11-17"} is_a: AISM:0000102 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! ring conjunctiva relationship: BFO:0000050 AISM:0000108 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect thorax property_value: IAO:0000232 "These conjunctivae can be used as stable reference points in insects that poseess legs, and can be used to define sclerites on the lateral side of the thorax." xsd:string {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-11-17"} [Term] id: AISM:0000174 name: insect region of cuticle {IAO:0000232="Modified 2023-04-13: added insect to specify.\njgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect region of integument that is part of the chitin-based cuticle." [] {creation_date="2020-11-23", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: BFO:0000004 ! independent continuant relationship: BFO:0000050 UBERON:0001001 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! part of chitin-based cuticle relationship: BFO:0000050 UBERON:6007284 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! part of insect region of integument property_value: IAO:0000232 "The AISM focuses on anatomical structures that are part of the insect (chitinous) cuticle. These structures are acellular regions of the integument. Regions of the insect cuticle with different mechanical properties (i.e. increased and descresed flexinility, thickness, and elasticity) are continuous with each other (e.g. sclerites are continuous with conjunctivae or resilin rich regions are continuous with regions with less resilin content)." xsd:string {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-11-23"} [Term] id: AISM:0000177 name: pore canal {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Pore canals: thin perforations of the cuticle.\""} def: "The orifice that is contained by the cuticle and connects the inside of the insect with the outside, is tubular, and whose diameter is smaller than 100 nm." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-02-04"} is_a: UBERON:0000161 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! orifice relationship: AISM:0000079 UBERON:0001002 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by cuticle relationship: RO:0000053 PATO:0001873 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! has characteristic cylindrical relationship: RO:0002008 CL:0000066 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coincident with epithelial cell property_value: IAO:0000232 "Should coincide with 'exactly one' epithelial cell, but that violates OWL specs." xsd:string {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-26"} [Term] id: AISM:0000178 name: acantha {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Acanthae: hairs without sockets, one per hypodermal cell.\""} def: "The solid cuticular protrusion that coincides with only one epidermal cell (smaller than the diameter of the epidermal cell)." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-02-04"} is_a: AISM:0000028 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! solid cuticular protrusion relationship: BFO:0000050 AISM:0000003 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! part of insect sclerite relationship: RO:0002008 CL:0000362 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coincident with epidermal cell property_value: IAO:0000232 "Should coincide with 'exactly one' epithelial cell, but that violates OWL specs." xsd:string {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-26"} [Term] id: AISM:0000180 name: tergal carina {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2025-03-16"} def: "The cuticular carina on a tergite (or notum)." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2025-03-16"} is_a: AISM:0000501 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2025-03-16"} ! cuticular carina relationship: BFO:0000050 AISM:0004128 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2025-03-16"} ! part of notum [Term] id: AISM:0000181 name: tibial spur {creation_date="2025-03-17", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The cuticular spur that is continuous with the distal margin of the tibia." [] {creation_date="2025-03-17", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000040 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2025-03-17"} ! cuticular spur [Term] id: AISM:0000185 name: sensillum chaeticum {IAO:0000232="Modified 2023-01-11: moved under cuticular sensilla; added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Sensillum chaeticum: shorter than sensillum trichodeum, thick-walled.\""} def: "The hairlike seta that is short and thick walled." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-02-08"} is_a: AISM:0004304 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular sensilla relationship: BFO:0000051 AISM:0000039 {IAO:0000232="Modified 2023-01-11: added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! has part cuticular seta relationship: RO:0000053 PATO:0002228 {IAO:0000232="Modified 2023-01-11: added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! has characteristic acuminate [Term] id: AISM:0000186 name: sensillum trichodeum {IAO:0000232="Modified 2023-01-11: moved under cuticular sensilla; added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Sensillum trichodeum: hair-like sensilla, seta associated with sensory cell.\""} def: "The cuticular seta that is elongated and acuminate." [] {creation_date="2022-06-20", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004304 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular sensilla relationship: BFO:0000051 AISM:0000039 {IAO:0000232="Modified 2023-01-11: added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! has part cuticular seta relationship: BFO:0000051 AISM:0000039 {IAO:0000232="Modified 2023-01-11: added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! has part cuticular seta relationship: RO:0000053 PATO:0001154 {IAO:0000232="Modified 2023-01-11: added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! has characteristic elongated relationship: RO:0000053 PATO:0002228 {IAO:0000232="Modified 2023-01-11: added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! has characteristic acuminate property_value: IAO:0000232 "Hairlike seta that is long." xsd:string {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-02-08"} [Term] id: AISM:0000187 name: sensillum coeloconicum {IAO:0000232="Modified 2023-01-11: moved under cuticular sensilla; added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Sensillum coeloconicum: sensillum with modified seta in a cavity, with narrowed external opening of surrounding cuticle.\""} def: "Seta that is located in the middle of a depression with narrowed external opening." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-02-08"} is_a: AISM:0004304 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular sensilla [Term] id: AISM:0000188 name: apodeme {AISM:0000171="Klass K-D (2001) The female abdomen of the viviparous earwig Hemimerus vosseleri (Insecta: Dermaptera: Hemimeridae), with a discussion of the postgenital abdomen of Insecta. Zoological Journal of the Linnean Society 131: 251–307. \n\nhttps://doi.org/10.1111/j.1096-3642.2001.tb02239.x \n\n\"tendon is used herein to designate sclerotized internal cuticular projections\"", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043\n\n\"Apodeme: solid cuticular invagination serving as muscle insertion area.\""} def: "The solid cuticular invagination of a sclerite." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000000 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular internal depression relationship: BFO:0000050 AISM:0000003 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! part of insect sclerite relationship: RO:0000053 PATO:0001873 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! has characteristic cylindrical [Term] id: AISM:0000189 name: sensillum basiconicum {IAO:0000232="Modified 2023-01-11: moved under cuticular sensilla; added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Sensillum basiconicum: sensillum with rounded, conical seta.\""} def: "The seta that is conical." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004304 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular sensilla relationship: BFO:0000051 AISM:0000039 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! has part cuticular seta relationship: RO:0000053 PATO:0002021 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! has characteristic conical [Term] id: AISM:0000190 name: antennifer {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Antennifer: small cephalic process articulating with the antenna.\""} def: "The cuticular protrusion of the head capsule thag is continuous with the antenniferal-scapal conjunctiva and adjacent to the cuticle of the scapus" [] {creation_date="2022-06-20", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000008 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular protrusion relationship: BFO:0000050 AISM:0000019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of head capsule relationship: RO:0002150 AISM:0004007 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with antenniferal-scapal conjunctiva relationship: RO:0002220 AISM:0000113 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! adjacent to scapus property_value: IAO:0000232 "The cuticular protrusion (process, protuberace) that bears the cranial articular surface of the cranio-antennal articulation." xsd:string {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-02-08"} [Term] id: AISM:0000191 name: tentorium {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Tentorium: cephalic endoskeleton, usually composed of paired anterior, posterior and dorsal tentorial arms and a transverse tentorial bridge (corpotentorium).\""} def: "The solid, paired, branching cuticular invagination of the head capsule that is attached to the antenna and the mouthparts via muscles." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000136 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! branching cuticular invagination is_a: AISM:0000188 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! apodeme is_a: UBERON:0000061 ! anatomical structure relationship: BFO:0000050 AISM:0000019 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! part of head capsule relationship: RO:0000053 PATO:0040024 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! has characteristic bilaterally paired property_value: IAO:0000232 "The paired apophysis that connects the posterior (ventral in prognathous head) and anterior (dorsal in prognathous head) walls of the head capsule and serves as site of isertion of atennal and mouthpart muscles." xsd:string {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-02-11"} [Term] id: AISM:0000192 name: tentorio-antennal muscle def: "The insect cranial muscle that is attached to the tentorium and to the antenna." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000080 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect cranial muscle relationship: RO:0002371 AISM:0000032 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! attached to antenna relationship: RO:0002371 AISM:0000191 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! attached to tentorium [Term] id: AISM:0000193 name: cuticular pit {term:modified="2021-12-10"} def: "The cuticular depression that corresponds to an apophysis." [] {creation_date="2021-02-12", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000156 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular fovea relationship: RO:0000053 PATO:0002078 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! has characteristic hollow relationship: RO:0002008 AISM:0000138 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coincident with cuticular apophysis [Term] id: AISM:0000194 name: anterior tentorial pit {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Anterior tentorial pit (or groove): externally visible invagination area and origin of anterior tentorial arm; adjacent with dorsolateral clypeal margin.\""} def: "The tentorial pit that correspods to the anterior (dorsal in prognathous head) end of the tentorium." [] {creation_date="2021-02-12", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000196 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! tentorial pit relationship: RO:0002220 AISM:0004038 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to anterior tentorial arm [Term] id: AISM:0000195 name: posterior tentorial pit {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Posterior tentorial pit (or groove): externally visible invagination of posterior part of head capsule and origin of posterior tentorial arm; adjacent with foramen occipitale or gula.\""} def: "The tentorial pit that correspods to the posterior (ventral in prognathous head) end of the tentorium." [] {creation_date="2021-02-12", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000196 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! tentorial pit relationship: RO:0002150 AISM:0004037 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with posterior tentorial arm [Term] id: AISM:0000196 name: tentorial pit def: "The cuticular pit that correspods to the tentorium." [] {creation_date="2021-02-12", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", term:modified="2021-12-10"} is_a: AISM:0000193 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular pit [Term] id: AISM:0000197 name: arthropod foramen def: "The foramen encircled by insect region of cuticle." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: UBERON:0000161 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! orifice relationship: AISM:0000079 AISM:0000174 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by insect region of cuticle [Term] id: AISM:0000198 name: antennal foramen def: "The arthropod foramen of the head capsule with the antennifer and surrounds the scapus via the antenniferal-scapal conjunctiva." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} synonym: "antennal socket" EXACT [] synonym: "torulus" EXACT [] {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"antennal socket = torulus = basal socket of antenna\""} is_a: AISM:0000197 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! arthropod foramen relationship: AISM:0000079 AISM:0000019 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by head capsule relationship: AISM:0000079 AISM:0004007 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by antenniferal-scapal conjunctiva [Term] id: AISM:0000199 name: tibial carina {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-03-16"} def: "The cuticular carina that is part of the tibia and parallel to the proximal-distal axis." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2025-03-16"} is_a: AISM:0000501 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2025-03-16"} ! cuticular carina relationship: BFO:0000050 AISM:0000075 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2025-03-16"} ! part of tibia relationship: parallel_to BSPO:0000015 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2025-03-16"} ! proximal-distal axis [Term] id: AISM:0000200 name: gonocoxa IX {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The paired sclerite of the postabdomen that is attached to the abdominal tergite IX by the abdominal tergite IX-gonocoxa IX conjunctiva and is articulated with abdominal tergite IX." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-03-19"} synonym: "second coxopodite" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Coxopodite (=valvifer, gonocoxa, gonocoxite): short basal piece of ovipositor elements of female genital segments VIII and IX.\""} synonym: "second gonocoxite" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Coxopodite (=valvifer, gonocoxa, gonocoxite): short basal piece of ovipositor elements of female genital segments VIII and IX.\""} synonym: "second valvifer" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Coxopodite (=valvifer, gonocoxa, gonocoxite): short basal piece of ovipositor elements of female genital segments VIII and IX.\""} is_a: AISM:0004301 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! gonocoxite relationship: RO:0002150 AISM:0000201 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal tergite IX-gonocoxa IX conjunctiva property_value: IAO:0000589 "cuticle of gonocoxa IX" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000201 name: abdominal tergite IX-gonocoxa IX conjunctiva def: "The conjunctiva of the postabdomen that connects the abdominal tergite IX and the gonocoxa IX." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-03-19"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: BFO:0000050 AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of postabdomen relationship: RO:0002150 AISM:0000200 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with gonocoxa IX relationship: RO:0002150 AISM:0004117 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal tergite IX [Term] id: AISM:0000301 name: protarsomere {creation_date="2023-05-04", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The tarsomere that is part of the protarsus." [] {creation_date="2023-05-04", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000074 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! tarsomere relationship: BFO:0000050 AISM:0004190 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! part of protarsus [Term] id: AISM:0000302 name: protarsomere 1 {creation_date="2023-05-04", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The protarsomere distal to the protibia and encircled by the protibio-protarsal conjunctiva." [] {creation_date="2023-05-04", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000301 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! protarsomere relationship: AISM:0000079 AISM:0004183 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! encircled by protibio-protarsal conjunctiva relationship: BSPO:0000097 AISM:0000067 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! distal to protibia [Term] id: AISM:0000303 name: protarsomere 2 {creation_date="2023-05-04", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The protarsomere that is distal to the protarsomere 1 and is encircled by the protarsomere 1-protarsomere 2 conjunctiva." [] {creation_date="2023-05-04", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000301 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! protarsomere relationship: AISM:0000079 AISM:0000319 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! encircled by protarsomere 1-protarsomere 2 conjunctiva relationship: BSPO:0000097 AISM:0000302 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! distal to protarsomere 1 [Term] id: AISM:0000304 name: protarsomere 3 {creation_date="2023-05-04", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The protarsomere that is distal to the protarsomere 2 and is encircled by the protarsomere 2-protarsomere 3 conjunctiva." [] {creation_date="2023-05-04", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000301 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! protarsomere relationship: AISM:0000079 AISM:0000320 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! encircled by protarsomere 2-protarsomere 3 conjunctiva relationship: BSPO:0000097 AISM:0000303 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! distal to protarsomere 2 [Term] id: AISM:0000305 name: protarsomere 4 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The protarsomere that is distal to the protarsomere 3 and is encircled by the protarsomere 3-protarsomere 4 conjunctiva." [] {creation_date="2023-05-04", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000301 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! protarsomere relationship: AISM:0000079 AISM:0000321 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! encircled by protarsomere 3-protarsomere 4 conjunctiva relationship: BSPO:0000097 AISM:0000304 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! distal to protarsomere 3 [Term] id: AISM:0000306 name: protarsomere 5 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The protarsomere that is distal to the protarsomere 4 and is encircled by the protarsomere 4-protarsomere 5 conjunctiva." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000301 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! protarsomere relationship: AISM:0000079 AISM:0000322 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! encircled by protarsomere 4-protarsomere 5 conjunctiva relationship: BSPO:0000097 AISM:0000305 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! distal to protarsomere 4 [Term] id: AISM:0000307 name: mesotarsomere {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The tarsomere that is part of the mesotarsus." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000074 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! tarsomere relationship: BFO:0000050 AISM:0004189 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! part of mesotarsus [Term] id: AISM:0000308 name: mesotarsomere 1 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The mesotarsomere that is distal to the mesotibia and is encircled by the mesotibio-mesotarsal conjunctiva." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000307 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsomere relationship: AISM:0000079 AISM:0004184 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by mesotibio-mesotarsal conjunctiva relationship: BSPO:0000097 AISM:0000068 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! distal to mesotibia [Term] id: AISM:0000309 name: mesotarsomere 2 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The mesotarsomere that is distal to the mesotarsomere 1 and is encircled by the mesotarsomere 1-mesotarsomere 2 conjunctiva." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000307 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsomere relationship: AISM:0000079 AISM:0000323 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by mesotarsomere 1-mesotarsomere 2 conjunctiva relationship: BSPO:0000097 AISM:0000308 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! distal to mesotarsomere 1 [Term] id: AISM:0000310 name: mesotarsomere 3 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The mesotarsomere that is distal to the mesotarsomere 2 and is encircled by the mesotarsomere 2-mesotarsomere 3 conjunctiva." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000307 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsomere relationship: AISM:0000079 AISM:0000324 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by mesotarsomere 2-mesotarsomere 3 conjunctiva relationship: BSPO:0000097 AISM:0000309 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! distal to mesotarsomere 2 [Term] id: AISM:0000311 name: mesotarsomere 4 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The mesotarsomere that is distal to the mesotarsomere 3 and is encircled by the mesotarsomere 3-mesotarsomere 4 conjunctiva." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000307 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsomere relationship: AISM:0000079 AISM:0000325 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by mesotarsomere 3-mesotarsomere 4 conjunctiva relationship: BSPO:0000097 AISM:0000310 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! distal to mesotarsomere 3 [Term] id: AISM:0000312 name: mesotarsomere 5 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The mesotarsomere that is distal to the mesotarsomere 4 and is encircled by the mesotarsomere 4-mesotarsomere 5 conjunctiva." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000307 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsomere relationship: AISM:0000079 AISM:0000326 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by mesotarsomere 4-mesotarsomere 5 conjunctiva relationship: BSPO:0000097 AISM:0000311 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! distal to mesotarsomere 4 [Term] id: AISM:0000313 name: metatarsomere {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The tarsomere that is part of the metatarsus." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000074 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! tarsomere relationship: BFO:0000050 AISM:0004188 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! part of metatarsus [Term] id: AISM:0000314 name: metatarsomere 1 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The metatarsomere that is distal to the metatibia and is encircled by the metatibio-metatarsal conjunctiva." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000313 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsomere relationship: AISM:0000079 AISM:0004185 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by metatibio-metatarsal conjunctiva relationship: BSPO:0000097 AISM:0000069 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! distal to metatibia [Term] id: AISM:0000315 name: metatarsomere 2 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The metatarsomere that is distal to the metatarsomere 1 and is encircled by the metatarsomere 1-metatarsomere 2 conjunctiva." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000313 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsomere relationship: AISM:0000079 AISM:0000327 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by metatarsomere 1-metatarsomere 2 conjunctiva relationship: BSPO:0000097 AISM:0000314 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! distal to metatarsomere 1 [Term] id: AISM:0000316 name: metatarsomere 3 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The metatarsomere that is distal to the metatarsomere 2 and is encircled by the metatarsomere 2-metatarsomere 3 conjunctiva." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000313 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsomere relationship: AISM:0000079 AISM:0000328 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by metatarsomere 2-metatarsomere 3 conjunctiva relationship: BSPO:0000097 AISM:0000315 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! distal to metatarsomere 2 [Term] id: AISM:0000317 name: metatarsomere 4 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The metatarsomere that is distal to the metatarsomere 3 and is encircled by the metatarsomere 3-metatarsomere 4 conjunctiva." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000313 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsomere relationship: AISM:0000079 AISM:0000329 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by metatarsomere 3-metatarsomere 4 conjunctiva relationship: BSPO:0000097 AISM:0000316 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! distal to metatarsomere 3 [Term] id: AISM:0000318 name: metatarsomere 5 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The metatarsomere that is distal to the metatarsomere 4 and is encircled by the metatarsomere 4-metatarsomere 5 conjunctiva." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000313 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsomere relationship: AISM:0000079 AISM:0000330 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by metatarsomere 4-metatarsomere 5 conjunctiva relationship: BSPO:0000097 AISM:0000317 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! distal to metatarsomere 4 [Term] id: AISM:0000319 name: protarsomere 1-protarsomere 2 conjunctiva {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The conjunctiva that is part of the protarsus, is encircled by protarsomere 2 and encircles protarsomere 2." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva relationship: AISM:0000078 AISM:0000303 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles protarsomere 2 relationship: AISM:0000079 AISM:0000302 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by protarsomere 1 relationship: BFO:0000050 AISM:0004190 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! part of protarsus [Term] id: AISM:0000320 name: protarsomere 2-protarsomere 3 conjunctiva {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The conjunctiva that is part of the protarsus, is encircled by protarsomere 2 and encircles protarsomere 3." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva relationship: AISM:0000078 AISM:0000304 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles protarsomere 3 relationship: AISM:0000079 AISM:0000303 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by protarsomere 2 relationship: BFO:0000050 AISM:0004190 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! part of protarsus [Term] id: AISM:0000321 name: protarsomere 3-protarsomere 4 conjunctiva {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The conjunctiva that is part of the protarsus, is encircled by protarsomere 3 and encircles protarsomere 4." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva relationship: AISM:0000078 AISM:0000305 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles protarsomere 4 relationship: AISM:0000079 AISM:0000304 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by protarsomere 3 relationship: BFO:0000050 AISM:0004190 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! part of protarsus [Term] id: AISM:0000322 name: protarsomere 4-protarsomere 5 conjunctiva {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The conjunctiva that is part of the protarsus, is encircled by protarsomere 4 and encircles protarsomere 5." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva relationship: AISM:0000078 AISM:0000306 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles protarsomere 5 relationship: AISM:0000079 AISM:0000305 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by protarsomere 4 relationship: BFO:0000050 AISM:0004190 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! part of protarsus [Term] id: AISM:0000323 name: mesotarsomere 1-mesotarsomere 2 conjunctiva {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The conjunctiva that is part of the mesotarsus, is encircled by mesotarsomere 1 and encircles mesotarsomere 2." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva relationship: AISM:0000078 AISM:0000309 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles mesotarsomere 2 relationship: AISM:0000079 AISM:0000308 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by mesotarsomere 1 relationship: BFO:0000050 AISM:0004189 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! part of mesotarsus [Term] id: AISM:0000324 name: mesotarsomere 2-mesotarsomere 3 conjunctiva {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The conjunctiva that is part of the mesotarsus, is encircled by mesotarsomere 2 and encircles mesotarsomere 3." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva relationship: AISM:0000078 AISM:0000310 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles mesotarsomere 3 relationship: AISM:0000079 AISM:0000309 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by mesotarsomere 2 relationship: BFO:0000050 AISM:0004189 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! part of mesotarsus [Term] id: AISM:0000325 name: mesotarsomere 3-mesotarsomere 4 conjunctiva {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The conjunctiva that is part of the mesotarsus, is encircled by mesotarsomere 3 and encircles mesotarsomere 4." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva relationship: AISM:0000078 AISM:0000311 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles mesotarsomere 4 relationship: AISM:0000079 AISM:0000310 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by mesotarsomere 3 relationship: BFO:0000050 AISM:0004189 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! part of mesotarsus [Term] id: AISM:0000326 name: mesotarsomere 4-mesotarsomere 5 conjunctiva {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The conjunctiva that is part of the mesotarsus, is encircled by mesotarsomere 4 and encircles mesotarsomere 5." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva relationship: AISM:0000078 AISM:0000312 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles mesotarsomere 5 relationship: AISM:0000079 AISM:0000311 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by mesotarsomere 4 relationship: BFO:0000050 AISM:0004189 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! part of mesotarsus [Term] id: AISM:0000327 name: metatarsomere 1-metatarsomere 2 conjunctiva {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The conjunctiva that is part of the metatarsus, is encircled by metatarsomere 1 and encircles metatarsomere 2." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva relationship: AISM:0000078 AISM:0000315 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles metatarsomere 2 relationship: AISM:0000079 AISM:0000314 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by metatarsomere 1 relationship: BFO:0000050 AISM:0004188 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! part of metatarsus [Term] id: AISM:0000328 name: metatarsomere 2-metatarsomere 3 conjunctiva {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The conjunctiva that is part of the metatarsus, is encircled by metatarsomere 2 and encircles metatarsomere 3." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva relationship: AISM:0000078 AISM:0000316 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles metatarsomere 3 relationship: AISM:0000079 AISM:0000315 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by metatarsomere 2 relationship: BFO:0000050 AISM:0004188 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! part of metatarsus [Term] id: AISM:0000329 name: metatarsomere 3-metatarsomere 4 conjunctiva {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The conjunctiva that is part of the metatarsus, is encircled by metatarsomere 3 and encircles metatarsomere 4." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva relationship: AISM:0000078 AISM:0000317 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles metatarsomere 4 relationship: AISM:0000079 AISM:0000316 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by metatarsomere 3 relationship: BFO:0000050 AISM:0004188 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! part of metatarsus [Term] id: AISM:0000330 name: metatarsomere 4-metatarsomere 5 conjunctiva {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The conjunctiva that is part of the metatarsus, is encircled by metatarsomere 4 and encircles metatarsomere 5." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva relationship: AISM:0000078 AISM:0000318 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles metatarsomere 5 relationship: AISM:0000079 AISM:0000317 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by metatarsomere 4 relationship: BFO:0000050 AISM:0004188 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! part of metatarsus [Term] id: AISM:0000331 name: protarsus with 5 protarsomeres {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The protarsus with protarsomeres 1-5." [] {term:modified="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0004190 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! protarsus relationship: BFO:0000051 AISM:0000302 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part protarsomere 1 relationship: BFO:0000051 AISM:0000303 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part protarsomere 2 relationship: BFO:0000051 AISM:0000304 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part protarsomere 3 relationship: BFO:0000051 AISM:0000305 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part protarsomere 4 relationship: BFO:0000051 AISM:0000306 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part protarsomere 5 [Term] id: AISM:0000332 name: mesotarsus with 5 mesotarsomeres {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The mesotarsus that is composed by mesotarsomeres 1-5." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0004189 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsus relationship: BFO:0000051 AISM:0000308 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part mesotarsomere 1 relationship: BFO:0000051 AISM:0000309 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part mesotarsomere 2 relationship: BFO:0000051 AISM:0000310 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part mesotarsomere 3 relationship: BFO:0000051 AISM:0000311 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part mesotarsomere 4 relationship: BFO:0000051 AISM:0000312 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part mesotarsomere 5 [Term] id: AISM:0000333 name: metatarsus with 5 metatarsomeres {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The metatarsus that is composed by metatarsomeres 1-5." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0004188 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsus relationship: BFO:0000051 AISM:0000314 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part metatarsomere 1 relationship: BFO:0000051 AISM:0000315 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part metatarsomere 2 relationship: BFO:0000051 AISM:0000316 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part metatarsomere 3 relationship: BFO:0000051 AISM:0000317 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part metatarsomere 4 relationship: BFO:0000051 AISM:0000318 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part metatarsomere 5 [Term] id: AISM:0000334 name: flagellomere 2 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The cuticle of the flagellomere that is distal to the flagellomere 1 and is encircled by the flagellomere 1-flagellomere 2 conjunctiva." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} synonym: "antennomere 4" EXACT [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000116 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere relationship: AISM:0000079 AISM:0000344 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 1-flagellomere 2 conjunctiva relationship: BSPO:0000097 AISM:0000117 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! distal to flagellomere 1 [Term] id: AISM:0000335 name: flagellomere 3 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The cuticle of the flagellomere that is distal to the flagellomere 2 and is encircled by the flagellomere 2-flagellomere 3 conjunctiva." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} synonym: "antennomere 5" EXACT [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000116 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere relationship: AISM:0000079 AISM:0000343 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 2-flagellomere 3 conjunctiva relationship: BSPO:0000097 AISM:0000334 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! distal to flagellomere 2 [Term] id: AISM:0000336 name: flagellomere 4 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The cuticle of the flagellomere that is distal to the flagellomere 3 and is encircled by the flagellomere 3-flagellomere 4 conjunctiva." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} synonym: "antennomere 6" EXACT [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000116 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere relationship: AISM:0000079 AISM:0000345 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 3-flagellomere 4 conjunctiva relationship: BSPO:0000097 AISM:0000335 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! distal to flagellomere 3 [Term] id: AISM:0000337 name: flagellomere 5 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The cuticle of the flagellomere that is distal to the flagellomere 4 and is encircled by the flagellomere 4-flagellomere 5 conjunctiva." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} synonym: "antennomere 7" EXACT [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000116 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere relationship: AISM:0000079 AISM:0000346 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 4-flagellomere 5 conjunctiva relationship: BSPO:0000097 AISM:0000336 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! distal to flagellomere 4 [Term] id: AISM:0000338 name: flagellomere 6 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The cuticle of the flagellomere that is distal to the flagellomere 5 and is encircled by the flagellomere 5-flagellomere 6 conjunctiva." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} synonym: "antennomere 8" EXACT [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000116 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere relationship: AISM:0000079 AISM:0000347 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 5-flagellomere 6 conjunctiva relationship: BSPO:0000097 AISM:0000337 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! distal to flagellomere 5 [Term] id: AISM:0000339 name: flagellomere 7 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The cuticle of the flagellomere that is distal to the flagellomere 6 and is encircled by the flagellomere 6-flagellomere 7 conjunctiva." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} synonym: "antennomere 9" EXACT [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000116 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere relationship: AISM:0000079 AISM:0000348 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 6-flagellomere 7 conjunctiva relationship: BSPO:0000097 AISM:0000338 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! distal to flagellomere 6 [Term] id: AISM:0000340 name: flagellomere 8 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The cuticle of the flagellomere that is distal to the flagellomere 7 and is encircled by the flagellomere 7-flagellomere 8 conjunctiva." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} synonym: "antennomere 10" EXACT [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000116 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere relationship: AISM:0000079 AISM:0000349 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 7-flagellomere 8 conjunctiva relationship: BSPO:0000097 AISM:0000339 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! distal to flagellomere 7 [Term] id: AISM:0000341 name: flagellomere 9 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The cuticle of the flagellomere that is distal to the flagellomere 8 and is encircled by the flagellomere 8-flagellomere 9 conjunctiva." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} synonym: "antennomere 11" EXACT [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000116 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere relationship: AISM:0000079 AISM:0000350 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 8-flagellomere 9 conjunctiva relationship: BSPO:0000097 AISM:0000340 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! distal to flagellomere 8 [Term] id: AISM:0000342 name: flagellomere 10 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The cuticle of the flagellomere that is distal to flagellomere 9 and is encircled by the flagellomere 9-flagellomere 10 conjunctiva." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} synonym: "antennomere 12" EXACT [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000116 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere relationship: AISM:0000079 AISM:0000351 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 9-flagellomere 10 conjunctiva relationship: BSPO:0000097 AISM:0000341 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! distal to flagellomere 9 [Term] id: AISM:0000343 name: flagellomere 2-flagellomere 3 conjunctiva {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The conjunctiva that is part of the antenna, is encircled by the flagellomere 2 and encircles the flagellomere 3." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva relationship: AISM:0000078 AISM:0000335 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles flagellomere 3 relationship: AISM:0000079 AISM:0000334 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 2 relationship: BFO:0000050 AISM:0000032 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! part of antenna [Term] id: AISM:0000344 name: flagellomere 1-flagellomere 2 conjunctiva {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The conjunctiva that is part of the antenna, is encircled by the flagellomere 1 and encircles the flagellomere 2." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva relationship: AISM:0000078 AISM:0000334 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles flagellomere 2 relationship: AISM:0000079 AISM:0000117 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 1 relationship: BFO:0000050 AISM:0000032 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! part of antenna [Term] id: AISM:0000345 name: flagellomere 3-flagellomere 4 conjunctiva {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The conjunctiva that is part of the antenna, is encircled by the flagellomere 3 and encircles the flagellomere 4." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva relationship: AISM:0000078 AISM:0000336 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles flagellomere 4 relationship: AISM:0000079 AISM:0000335 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 3 relationship: BFO:0000050 AISM:0000032 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! part of antenna [Term] id: AISM:0000346 name: flagellomere 4-flagellomere 5 conjunctiva {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The conjunctiva that is part of the antenna, is encircled by the flagellomere 4 and encircles the flagellomere 5." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva relationship: AISM:0000078 AISM:0000337 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles flagellomere 5 relationship: AISM:0000079 AISM:0000336 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 4 relationship: BFO:0000050 AISM:0000032 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! part of antenna [Term] id: AISM:0000347 name: flagellomere 5-flagellomere 6 conjunctiva {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The conjunctiva that is part of the antenna, is encircled by the flagellomere 5 and encircles the flagellomere 6." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva relationship: AISM:0000078 AISM:0000338 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles flagellomere 6 relationship: AISM:0000079 AISM:0000337 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 5 relationship: BFO:0000050 AISM:0000032 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! part of antenna [Term] id: AISM:0000348 name: flagellomere 6-flagellomere 7 conjunctiva {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The conjunctiva that is part of the antenna, is encircled by the flagellomere 6 and encircles the flagellomere 7." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva relationship: AISM:0000078 AISM:0000339 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles flagellomere 7 relationship: AISM:0000079 AISM:0000338 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 6 relationship: BFO:0000050 AISM:0000032 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! part of antenna [Term] id: AISM:0000349 name: flagellomere 7-flagellomere 8 conjunctiva {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The conjunctiva that is part of the antenna, is encircled by the flagellomere 7 and encircles the flagellomere 8." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva relationship: AISM:0000078 AISM:0000340 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles flagellomere 8 relationship: AISM:0000079 AISM:0000339 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 7 relationship: BFO:0000050 AISM:0000032 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! part of antenna [Term] id: AISM:0000350 name: flagellomere 8-flagellomere 9 conjunctiva {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The conjunctiva that is part of the antenna, is encircled by the flagellomere 8 and encircles the flagellomere 9." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva relationship: AISM:0000078 AISM:0000341 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles flagellomere 9 relationship: AISM:0000079 AISM:0000340 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 8 relationship: BFO:0000050 AISM:0000032 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! part of antenna [Term] id: AISM:0000351 name: flagellomere 9-flagellomere 10 conjunctiva {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The conjunctiva that is part of the antenna, is encircled by the flagellomere 9 and encircles the flagellomere 10." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva relationship: AISM:0000078 AISM:0000342 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles flagellomere 10 relationship: AISM:0000079 AISM:0000341 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 9 relationship: BFO:0000050 AISM:0000032 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! part of antenna [Term] id: AISM:0000352 name: microreticulate {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "A structural quality inhering in a bearer by virtue of the bearer's having its surface covered with microscopic cuticular grooves forming a network." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000353 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} ! reticulate relationship: BFO:0000051 AISM:0000157 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} ! has part cuticular groove [Term] id: AISM:0000353 name: reticulate {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "A structural quality inhering in a bearer by virtue of the bearer's presenting on its surface a network of raised and interconnected wrinkles." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: PATO:0000150 {IAO:0000232="Modified 2024-02-14: moved as subclass of texture\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! texture [Term] id: AISM:0000354 name: isodiametrically microreticulate {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "A structural quality inhering in a bearer by virtue of the bearer's being microreticulate and having meshes of isometric diameter." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000352 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} ! microreticulate is_a: PATO:0001573 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} ! isometrical [Term] id: AISM:0000355 name: abdomen with 7 sternites {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The insect abdomen that has abdominal sternites 1-7 and does not have abdominal sternite 8." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000109 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! insect abdomen relationship: BFO:0000051 AISM:0004100 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part abdominal sternite I relationship: BFO:0000051 AISM:0004104 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part abdominal sternite II relationship: BFO:0000051 AISM:0004105 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part abdominal sternite III relationship: BFO:0000051 AISM:0004106 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part abdominal sternite IV relationship: BFO:0000051 AISM:0004107 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part abdominal sternite V relationship: BFO:0000051 AISM:0004108 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part abdominal sternite VI relationship: BFO:0000051 AISM:0004109 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part abdominal sternite VII [Term] id: AISM:0000356 name: abdomen with 8 sternites {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The insect abdomen that has abdominal sternites 1-8 and does not have abdominal sternite 9." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000109 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! insect abdomen relationship: BFO:0000051 AISM:0004100 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part abdominal sternite I relationship: BFO:0000051 AISM:0004104 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part abdominal sternite II relationship: BFO:0000051 AISM:0004105 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part abdominal sternite III relationship: BFO:0000051 AISM:0004106 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part abdominal sternite IV relationship: BFO:0000051 AISM:0004107 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part abdominal sternite V relationship: BFO:0000051 AISM:0004108 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part abdominal sternite VI relationship: BFO:0000051 AISM:0004109 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part abdominal sternite VII relationship: BFO:0000051 AISM:0004110 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part abdominal sternite VIII [Term] id: AISM:0000357 name: antenna with 8 antennomeres {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The antenna that has scapus, pedicellus, and flagellomeres 1-6, and does not have flagellomere 7." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000032 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! antenna relationship: BFO:0000051 AISM:0000334 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part flagellomere 2 relationship: BFO:0000051 AISM:0000335 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part flagellomere 3 relationship: BFO:0000051 AISM:0000336 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part flagellomere 4 relationship: BFO:0000051 AISM:0000337 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part flagellomere 5 relationship: BFO:0000051 AISM:0000338 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part flagellomere 6 [Term] id: AISM:0000358 name: antenna with 9 antennomeres {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The antenna that has scapus, pedicellus, and flagellomeres 1-7, and does not have flagellomere 8." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000032 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! antenna relationship: BFO:0000051 AISM:0000334 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part flagellomere 2 relationship: BFO:0000051 AISM:0000335 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part flagellomere 3 relationship: BFO:0000051 AISM:0000336 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part flagellomere 4 relationship: BFO:0000051 AISM:0000337 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part flagellomere 5 relationship: BFO:0000051 AISM:0000338 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part flagellomere 6 relationship: BFO:0000051 AISM:0000339 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part flagellomere 7 [Term] id: AISM:0000359 name: clypeal tooth {creation_date="2022-10-30", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The cuticular protrusion on the anterior margin of the clypeus." [] {term:modified="18-11-2023", creation_date="2023-03-28", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000407 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", term:modified="18-11-2023", creation_date="2023-03-28"} ! cuticular tooth [Term] id: AISM:0000360 name: medial clypeal tooth {creation_date="2022-10-30", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The clypeal tooth that is not bilaterally paired and located in the medial region." [] {creation_date="2022-10-30", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000359 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2022-10-30"} ! clypeal tooth relationship: RO:0001025 BSPO:0000083 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"} ! located in medial region [Term] id: AISM:0000361 name: lateral clypeal tooth {creation_date="2022-10-30", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The clypeal tooth that is bilaterally paired and located in the lateral region." [] {creation_date="2022-10-30", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000359 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2022-10-30"} ! clypeal tooth relationship: RO:0000053 PATO:0040024 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2022-10-30"} ! has characteristic bilaterally paired relationship: RO:0001025 BSPO:0000082 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"} ! located in lateral region [Term] id: AISM:0000362 name: lateral clypeal tooth 1 {creation_date="2022-10-30", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The lateral clypeal tooth that is lateral to the medial region." [] {creation_date="2022-10-30", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000361 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2022-10-30"} ! lateral clypeal tooth relationship: AISM:0000011 BSPO:0000083 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"} ! lateral_to medial region [Term] id: AISM:0000363 name: lateral clypeal tooth 2 {creation_date="2022-10-30", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The lateral clypeal tooth that is lateral to the lateral clypeal tooth 1." [] {creation_date="2022-10-30", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000361 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2022-10-30"} ! lateral clypeal tooth relationship: AISM:0000011 AISM:0000362 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"} ! lateral_to lateral clypeal tooth 1 [Term] id: AISM:0000364 name: lateral clypeal tooth 3 {creation_date="2022-10-30", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The lateral clypeal tooth that is lateral to the lateral clypeal tooth 2." [] {creation_date="2022-10-30", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000361 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2022-10-30"} ! lateral clypeal tooth relationship: AISM:0000011 AISM:0000363 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"} ! lateral_to lateral clypeal tooth 2 [Term] id: AISM:0000365 name: tibial cuticular tooth {creation_date="2022-10-14", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The cuticular protrusion of the cuticle of tibia." [] {term:modified="18-11-2023", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"} is_a: AISM:0000407 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", term:modified="18-11-2023", creation_date="2023-03-28"} ! cuticular tooth relationship: BFO:0000050 AISM:0000075 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"} ! part of tibia [Term] id: AISM:0000366 name: protibial cuticular tooth {creation_date="2022-10-14", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The cuticular protrusion of the cuticle of protibia." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"} is_a: AISM:0000365 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"} ! tibial cuticular tooth relationship: BFO:0000050 AISM:0000067 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"} ! part of protibia [Term] id: AISM:0000367 name: dorsal protibial cuticular tooth {creation_date="2022-10-14", IAO:0000232="Modified and moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The protibial cuticular tooth on the posterior margin." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", term:modified="2023-05-03", creation_date="2023-03-28", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000366 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"} ! protibial cuticular tooth [Term] id: AISM:0000368 name: dorsal protibial cuticular tooth 1 {term:modified="2023-05-03", creation_date="2022-10-14", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The dorsal protibial cuticular tooth that is proximal to the distal margin of the tibia." [] {creation_date="2023-03-30", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", term:modified="2023-05-03", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000367 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"} ! dorsal protibial cuticular tooth [Term] id: AISM:0000369 name: dorsal protibial cuticular tooth 2 {term:modified="2023-05-03", creation_date="2022-10-14", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The dorsal protibial cuticular tooth that is proximal to the dorsal protibial cuticular tooth 1." [] {creation_date="2023-03-30", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", term:modified="2023-05-03", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000367 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"} ! dorsal protibial cuticular tooth relationship: BSPO:0000100 AISM:0000368 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-30"} ! proximal to dorsal protibial cuticular tooth 1 [Term] id: AISM:0000370 name: dorsal protibial cuticular tooth 3 {term:modified="2023-05-03", creation_date="2022-10-14", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The dorsal protibial cuticular tooth that is proximal to the dorsal protibial cuticular tooth 2." [] {creation_date="2023-03-30", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", term:modified="2023-05-03", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000367 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"} ! dorsal protibial cuticular tooth relationship: BSPO:0000100 AISM:0000369 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-30"} ! proximal to dorsal protibial cuticular tooth 2 [Term] id: AISM:0000371 name: dorsal protibial cuticular tooth 4 {term:modified="2023-05-03", creation_date="2022-10-14", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The dorsal protibial cuticular tooth that is proximal to the dorsal protibial cuticular tooth 3." [] {creation_date="2023-03-30", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", term:modified="2023-05-03", comment="", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000367 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"} ! dorsal protibial cuticular tooth relationship: BSPO:0000100 AISM:0000370 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-30"} ! proximal to dorsal protibial cuticular tooth 3 [Term] id: AISM:0000372 name: left paramere {IAO:0000232="Modified 2023-04-15: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-04-04"} def: "The cuticle of the paramere that is located in the left side of the body." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-04-04"} property_value: IAO:0000589 "cuticle of left paramere" xsd:string {creation_date="2023-04-15"} [Term] id: AISM:0000373 name: right paramere {IAO:0000232="Modified 2023-04-15: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-04-04"} def: "The cuticle of the paramere that is located in the right side of the body." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-04-04"} property_value: IAO:0000589 "cuticle of right paramere" xsd:string {creation_date="2023-04-15"} [Term] id: AISM:0000374 name: tibial margin {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2025-03-16"} def: "The anatomical margin that is part of the tibia." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2025-03-16"} is_a: BSPO:0000678 ! distal margin [Term] id: AISM:0000375 name: anterior groove of tergite VIII {creation_date="2023-06-04", IAO:0000232="Modified and moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The cuticular groove that is parallel and distal to the proximal carina of tergite VIII." [] {creation_date="2023-06-04", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000157 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-06-04"} ! cuticular groove relationship: BSPO:0000097 AISM:0000377 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-06-04"} ! distal to proximal carina of tergite VIII relationship: parallel_to AISM:0000377 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-06-04"} ! proximal carina of tergite VIII [Term] id: AISM:0000376 name: interpunctural distance {creation_date="2023-06-04", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The distance between two cuticular punctures." [] {creation_date="2023-06-04", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} property_value: IAO:0000232 "Edited by jgiron https://orcid.org/0000-0002-0851-6883 \n2024-05-11\nTo make it a distance as opposed to an anatomical space and change 'adjacent to' for 'characteristic of'\nMatching existing definitions e.g. http://purl.obolibrary.org/obo/AGRO_00000318\n\nFormer definition based on suggestions at https://github.com/obophenotype/uberon/issues/3188" xsd:string {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} [Term] id: AISM:0000377 name: proximal carina of tergite VIII {creation_date="2023-06-04", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The cuticular carina that is located on the proximal margin of the 8th tergite and is parallel to the left-right body axis." [] {creation_date="2023-06-04", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} synonym: "pygidium basal ridge" EXACT [] {creation_date="2023-06-04", AISM:0000171="Tarasov, S. I., & Solodovnikov, A. Y. (2011). Phylogenetic analyses reveal reliable morphological markers to classify mega‐diversity in Onthophagini dung beetles (Coleoptera: Scarabaeidae: Scarabaeinae). Cladistics, 27(5), 490-528. https://doi.org/10.1111/j.1096-0031.2011.00351.x\n \nPage 526, character 30", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000180 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-06-04"} ! tergal carina relationship: parallel_to BSPO:0000017 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-06-04"} ! left-right axis property_value: IAO:0000232 "In Scarabaeinae, this carina (when present) is located in the proximalmost margin of the surface of the 8th tergite (pygidium) that is not covered by elytra." xsd:string {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-06-04"} [Term] id: AISM:0000378 name: granulate cuticular puncture {creation_date="2023-06-04", AISM:0000171="Orbigny, H. d’ (1913) [1913-1914]. Synopsis des Onthophagides d’Afrique. Annales de la Société entomologique de France, 82 : 1-742.\nhttps://www.biodiversitylibrary.org/page/8239919\n\n\"la ponctuation peut être râpeuse ou granuleuse, c'est-à-dire composée de points dont le bord antérieur s'élève en une aspérité irrégulière, ou en un granule arrondi qui ordinaireauent échancre plus ou moins ce bord antérieur\" p. 4", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The cuticular puncture that has a cuticular granule on its anterior margin." [] {creation_date="2023-06-04", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000524 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-06-04"} ! cuticular puncture [Term] id: AISM:0000379 name: ocellate cuticular puncture {creation_date="2023-06-04", AISM:0000171="Orbigny, H. d’ (1913) [1913-1914]. Synopsis des Onthophagides d’Afrique. Annales de la Société entomologique de France, 82 : 1-742.\n\nhttps://www.biodiversitylibrary.org/page/8239919\n\n\"... soit grands et à fond plat, ou ocellés, c'est-à-dire grands et à fond convexe, ou ombiliqués, c'est-à-dire grands, peu profonds et ayant dans l'intérieur un petit point plus profond\" p. 4", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The cuticular puncture that is flattened." [] {creation_date="2023-06-04", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} [Term] id: AISM:0000380 name: posterior carina of tergite VIII {creation_date="2023-06-04", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The cuticular carina that is located along the posterior margin of abdominal tergite VIII." [] {creation_date="2023-06-04", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} synonym: "ribordo del margine ventrale del pigidio" EXACT [] {creation_date="2023-06-04", AISM:0000171="Marchisio, R., & Zunino, M. E. (2012). Il genere Copris Müller. Tassonomia, filogenesi e note di zoogeografia (Vol. 2, pp. 1-176). world biodiversity association onlus.\n\nPage 26", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000180 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-06-04"} ! tergal carina [Term] id: AISM:0000381 name: head margin at genoclypeal sulcus {creation_date="2023-06-04", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The anatomical margin that is part of the anterior margin of the gena and of the lateral region of the posterior margin of the clypeus." [] {creation_date="2023-06-04", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: BSPO:0000006 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-06-04"} ! anatomical margin property_value: IAO:0000232 "Corresponds with the region of the clypeal margin next to the distal end of the genoclypeal sulcus." xsd:string {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-06-04"} [Term] id: AISM:0000382 name: carina of vertex {IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-04-06", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The cuticular carina that is part of the vertex and parallel to the left-right body axis." [] {creation_date="2023-04-06", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} relationship: parallel_to BSPO:0000017 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-06-04"} ! left-right axis [Term] id: AISM:0000383 name: clypeal carina {IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-04-06", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The cuticular carina that is part of the clypeus and is parallel to the left-right body axis." [] {creation_date="2023-04-06", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} relationship: parallel_to BSPO:0000017 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-06-04"} ! left-right axis [Term] id: AISM:0000384 name: row of punctures {creation_date="2023-05-03", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "An anatomical row composed by cuticular punctures." [] {creation_date="2023-05-03", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: UBERON:0034926 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-03"} ! anatomical row relationship: BFO:0000051 AISM:0000524 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-03"} ! has part cuticular puncture [Term] id: AISM:0000385 name: clypeal margin {creation_date="2023-05-03", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The anatomical margin of the anterior region of clypeus." [] {creation_date="2023-05-03", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} [Term] id: AISM:0000386 name: genal margin {creation_date="2023-05-03", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The anatomical margin of the lateral region of the gena." [] {creation_date="2023-05-03", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} [Term] id: AISM:0000387 name: ventral conjunctiva of paramere {AISM:0000171="Rossini, M., Grebennikov, V., Merrien, T., Miraldo, A., Viljanen, H., & Tarasov, S. (2022). Paleogene forest fragmentation and out‐of‐Africa dispersal explain radiation of the Paleotropical dung beetle tribe Epactoidini trib. nov.(Coleoptera: Scarabaeinae). Systematic Entomology, 47(4), 655-667.\nhttps://doi.org/10.1111/syen.12564\n\nFigure 2d", creation_date="2023-05-04", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The ventral region of the cuticle of paramere that has decreased thickness." [] {creation_date="2023-05-04", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} relationship: RO:0000053 PATO:0000592 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! has characteristic decreased thickness [Term] id: AISM:0000388 name: left ventral conjunctiva of paramere {creation_date="2023-05-08", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The ventral conjunctiva of the left paramere." [] {creation_date="2023-05-08", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000387 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! ventral conjunctiva of paramere relationship: BFO:0000050 AISM:0000372 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! part of left paramere [Term] id: AISM:0000389 name: right ventral conjunctiva of paramere {creation_date="2023-05-04", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The ventral conjunctiva of the right paramere." [] {creation_date="2023-05-04", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000387 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! ventral conjunctiva of paramere relationship: BFO:0000050 AISM:0000373 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! part of right paramere [Term] id: AISM:0000390 name: protibial apex adjacent to protibio-protarsal articulation {creation_date="2023-05-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The region of the cuticle part of the distal posterior region of protibia and adjacent to the protibio-protarsal articulation." [] {creation_date="2023-05-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000174 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-10"} ! insect region of cuticle relationship: RO:0002220 AISM:0000391 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-10"} ! adjacent to insect protibio-protarsal articulation [Term] id: AISM:0000391 name: insect protibio-protarsal articulation {creation_date="2023-05-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The articulation between the protibia and the protarsus." [] {creation_date="2023-05-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000002 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-10"} ! insect articulation [Term] id: AISM:0000392 name: parameres {creation_date="2023-05-30", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The region of the insect cuticle that has left and right parameres." [] {creation_date="2023-05-30", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000174 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! insect region of cuticle relationship: BFO:0000051 AISM:0000372 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! has part left paramere relationship: BFO:0000051 AISM:0000373 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! has part right paramere property_value: IAO:0000232 "This term has been created to indicate simultaneously left and right parameres, in order to be able to use on it the qualities \"symmetrical\" and \"asymmetrical\", which are not applicable to single parameres." xsd:string {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} [Term] id: AISM:0000393 name: maxillary palpus with 4 palpomeres {creation_date="2023-05-30", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The maxillary palpus that has maxillary palpomeres I to IV but not maxillary palpomere V." [] {creation_date="2023-05-30", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000051 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! maxillary palpus relationship: BFO:0000051 AISM:0002037 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! has part maxillary palpomere I relationship: BFO:0000051 AISM:0002038 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! has part maxillary palpomere II relationship: BFO:0000051 AISM:0002039 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! has part maxillary palpomere III relationship: BFO:0000051 AISM:0002040 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! has part maxillary palpomere IV [Term] id: AISM:0000394 name: labial palpomere I {creation_date="2023-05-30", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The labial palpomere that is adjacent to the distal margin of the palpiger." [] {creation_date="2023-05-30", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000060 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! labial palpomere relationship: AISM:0000079 AISM:0004017 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! encircled by palpigero-palpal conjunctiva [Term] id: AISM:0000395 name: labial palpomere II {creation_date="2023-05-30", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The labial palpomere that is adjacent to the distal margin of the labial palpomere I." [] {creation_date="2023-05-30", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000060 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! labial palpomere [Term] id: AISM:0000396 name: labial palpomere III {creation_date="2023-05-30", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The labial palpomere that is adjacent to the distal margin of the labial palpomere II." [] {creation_date="2023-05-30", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000060 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! labial palpomere [Term] id: AISM:0000397 name: labial palpus with 3 palpomeres {creation_date="2023-05-30", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The labial palpus that has labial palpomeres I to III." [] {creation_date="2023-05-30", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000024 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! labial palpus relationship: BFO:0000051 AISM:0000394 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! has part labial palpomere I relationship: BFO:0000051 AISM:0000395 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! has part labial palpomere II relationship: BFO:0000051 AISM:0000396 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! has part labial palpomere III [Term] id: AISM:0000405 name: antero-distal margin {creation_date="2023-11-17", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The anatomical margin that overlaps with the distal side and the anterior side." [] {creation_date="2023-11-17", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: BSPO:0000671 ! anterior margin is_a: BSPO:0000678 ! distal margin [Term] id: AISM:0000406 name: postero-distal margin {creation_date="2023-11-17", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The anatomical margin that overlaps with the distal side and the posterior side." [] {creation_date="2023-11-17", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: BSPO:0000672 ! posterior margin is_a: BSPO:0000678 ! distal margin [Term] id: AISM:0000407 name: cuticular tooth {creation_date="2023-11-18", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The cuticular protrusion that is located on an anatomical margin." [] {creation_date="2023-11-18", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} [Term] id: AISM:0000408 name: setigerous cuticular puncture {creation_date="2023-12-03", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The cuticular puncture that encircles a cuticular seta." [] {creation_date="2023-12-03", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} [Term] id: AISM:0000409 name: granulate setigerous cuticular puncture {creation_date="2023-12-03", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The setigerous cuticular puncture that has a cuticular granule on its anterior margin." [] {creation_date="2023-12-03", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000408 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-12-03"} ! setigerous cuticular puncture [Term] id: AISM:0000410 name: ocellate setigerous cuticular puncture {creation_date="2023-12-03", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The setigerous cuticular puncture that is flattened." [] {creation_date="2023-12-03", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} [Term] id: AISM:0000411 name: simple setigerous cuticular puncture {creation_date="2023-12-03", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The setigerous cuticular puncture that is flattened and does not have a cuticular granule." [] {creation_date="2023-12-03", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000408 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-12-03"} ! setigerous cuticular puncture [Term] id: AISM:0000412 name: cuticle with setigerous punctures {creation_date="2023-12-03", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The region of the insect cuticle that is covered by a collection of setigerous cuticular punctures." [] {creation_date="2023-12-03", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000174 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-12-03"} ! insect region of cuticle relationship: BFO:0000051 UBERON:0034925 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-12-03"} ! has part anatomical collection relationship: RO:0002351 AISM:0000408 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-12-03"} ! has member setigerous cuticular puncture [Term] id: AISM:0000413 name: distal region of tergite VIII {creation_date="2025-02-21", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The region of the cuticle of tergite VIII that is posterior to the posterior carina of tergite VIII and anterior to the tergite's distal margin." [] {creation_date="2025-02-21", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000174 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-21"} ! insect region of cuticle relationship: BFO:0000050 AISM:0004097 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-21"} ! part of abdominal tergite VIII relationship: BSPO:0000099 AISM:0000380 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-21"} ! posterior to posterior carina of tergite VIII [Term] id: AISM:0000414 name: clypeal margin between clypeal teeth 1 and 2 {creation_date="2025-02-21", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The bilaterally paired anatomical margin part of the anterior region of the clypeal margin that is lateral to lateral clypeal teeth 1 and medial to latera clypeal tooth 2." [] {creation_date="2025-02-21", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000385 ! clypeal margin relationship: AISM:0000011 AISM:0000362 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-21"} ! lateral_to lateral clypeal tooth 1 relationship: AISM:0000012 AISM:0000363 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-21"} ! medial_to lateral clypeal tooth 2 relationship: RO:0000086 PATO:0040024 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-21"} ! has quality bilaterally paired [Term] id: AISM:0000415 name: clypeal margin between clypeal teeth 1 {creation_date="2025-02-21", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The not bilaterally paired anatomical margin part of the of the anterior region of the clypeal margin that is adjacent to lateral clypeal tooth 1 but not adjacent to the medial clypeal tooth." [] {creation_date="2025-02-21", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000385 ! clypeal margin relationship: RO:0002220 AISM:0000362 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-21"} ! adjacent to lateral clypeal tooth 1 [Term] id: AISM:0000416 name: clypeal margin between clypeal tooth 1 and medial clypeal tooth {creation_date="2025-02-21", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The bilaterally paired anatomical margin part of the anterior region of the clypeal margin that is lateral to lateral clypeal tooth 1 and medial to latera clypeal tooth 2." [] {creation_date="2025-02-21", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000385 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-21"} ! clypeal margin relationship: AISM:0000011 AISM:0000362 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-21"} ! lateral_to lateral clypeal tooth 1 relationship: AISM:0000012 AISM:0000363 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-21"} ! medial_to lateral clypeal tooth 2 relationship: RO:0000086 PATO:0040024 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-21"} ! has quality bilaterally paired [Term] id: AISM:0000417 name: dorsal protibial margin between protibial teeth 1 and 2 {creation_date="2025-02-21", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The anatomical margin part of the dorsal protibial margin that is proximal to dorsal protibial cuticular tooth 1 and distal to dorsal protibial cuticular tooth 2." [] {creation_date="2025-02-21", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000374 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-21"} ! tibial margin relationship: BSPO:0000097 AISM:0000369 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-21"} ! distal to dorsal protibial cuticular tooth 2 relationship: BSPO:0000100 AISM:0000368 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-21"} ! proximal to dorsal protibial cuticular tooth 1 [Term] id: AISM:0000418 name: dorsal protibial margin between protibial teeth 2 and 3 {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The anatomical margin part of the dorsal protibial margin that is proximal to dorsal protibial cuticular tooth 2 and distal to dorsal protibial cuticular tooth 3." [] {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000374 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! tibial margin relationship: BSPO:0000097 AISM:0000370 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! distal to dorsal protibial cuticular tooth 3 relationship: BSPO:0000100 AISM:0000369 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! proximal to dorsal protibial cuticular tooth 2 [Term] id: AISM:0000419 name: dorsal protibial margin between protibial teeth 3 and 4 {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The anatomical margin part of the dorsal protibial margin that is proximal to dorsal protibial cuticular tooth 3 and distal to dorsal protibial cuticular tooth 4." [] {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000374 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! tibial margin relationship: BSPO:0000097 AISM:0000371 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! distal to dorsal protibial cuticular tooth 4 relationship: BSPO:0000100 AISM:0000370 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! proximal to dorsal protibial cuticular tooth 3 [Term] id: AISM:0000420 name: dorsal protibial margin proximal to protibial tooth 4 {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The anatomical margin part of the dorsal protibial margin that is proximal to dorsal protibial cuticular tooth 4 and distal to the profemoro-protibial conjunctiva." [] {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000374 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! tibial margin relationship: BSPO:0000097 AISM:0004179 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! distal to profemoro-protibial conjunctiva relationship: BSPO:0000100 AISM:0000371 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! proximal to dorsal protibial cuticular tooth 4 [Term] id: AISM:0000421 name: dorsal protibial margin between protibial spur and protibial tooth 1 {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The anatomical margin part of the dorsal protibial margin that is proximal to the protibial spur and distal to the dorsal protibial cuticular tooth 1." [] {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000374 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! tibial margin relationship: BSPO:0000097 AISM:0000368 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! distal to dorsal protibial cuticular tooth 1 relationship: BSPO:0000100 AISM:0000371 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! proximal to dorsal protibial cuticular tooth 4 [Term] id: AISM:0000422 name: protibial spur {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The cuticular spur that is encircled by the protibio-protarsal spur conjunctiva." [] {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000181 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! tibial spur relationship: AISM:0000079 AISM:0000423 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! encircled by protibio-protibial spur conjunctiva [Term] id: AISM:0000423 name: protibio-protibial spur conjunctiva {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The conjunctiva that enricles the protibial spur and is encircled by the protibia." [] {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! conjunctiva relationship: AISM:0000078 AISM:0000422 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! encircles protibial spur relationship: AISM:0000079 AISM:0000067 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! encircled by protibia [Term] id: AISM:0000424 name: mesotibial carina {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The tibial carina that is part of the mesotibia." [] {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000199 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! tibial carina relationship: BFO:0000050 AISM:0000068 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! part of mesotibia [Term] id: AISM:0000425 name: metatibial carina {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The tibial carina that is part of the metatibia." [] {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000199 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! tibial carina relationship: BFO:0000050 AISM:0000069 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! part of metatibia [Term] id: AISM:0000426 name: mesotibial posteroventral carina {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The mesotibial carina that is located in the postero-ventral region of the mesotibia." [] {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000424 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! mesotibial carina [Term] id: AISM:0000427 name: mesotibial anteroventral carina {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The mesotibial carina that is located in the antero-ventral region of the mesotibia." [] {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000424 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! mesotibial carina [Term] id: AISM:0000428 name: mesotibial anterodorsal carina {creation_date="2025-03-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The mesotibial carina that is located in the antero-dorsal region of the mesotibia." [] {creation_date="2025-03-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000424 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-10"} ! mesotibial carina [Term] id: AISM:0000429 name: mesotibial posterodorsal carina {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The mesotibial carina that is located in the postero-dorsal region of the mesotibia." [] {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000424 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! mesotibial carina [Term] id: AISM:0000430 name: metatibial posteroventral carina {creation_date="2025-03-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The metatibial carina that is located in the antero-dorsal region of the metatibia." [] {creation_date="2025-03-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000425 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-10"} ! metatibial carina [Term] id: AISM:0000431 name: metatibial anteroventral carina {creation_date="2025-03-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The metatibial carina that is located in the postero-ventral region of the metatibia." [] {creation_date="2025-03-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000425 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-10"} ! metatibial carina [Term] id: AISM:0000432 name: metatibial anterodorsal carina {creation_date="2025-03-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The metatibial carina that is located in the antero-dorsal region of the metatibia." [] {creation_date="2025-03-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000425 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-10"} ! metatibial carina [Term] id: AISM:0000433 name: metatibial posterodorsal carina {creation_date="2025-03-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The metatibial carina that is located in the postero-dorsal region of the metatibia." [] {creation_date="2025-03-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000425 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-10"} ! metatibial carina [Term] id: AISM:0000434 name: mesotibial spur {creation_date="2025-03-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The cuticular spur encircled by the mesotibio-mesotibial spur conjunctiva." [] {creation_date="2025-03-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000181 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-10"} ! tibial spur relationship: AISM:0000079 AISM:0000436 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-10"} ! encircled by mesotibio-mesotibial spur conjunctiva [Term] id: AISM:0000435 name: metatibial spur {creation_date="2025-03-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The cuticular spur encircled by the metatibio-metatibial spur conjunctiva." [] {creation_date="2025-03-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000181 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-10"} ! tibial spur relationship: AISM:0000079 AISM:0000437 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-10"} ! encircled by metatibio-metatibial spur conjunctiva [Term] id: AISM:0000436 name: mesotibio-mesotibial spur conjunctiva {creation_date="2025-03-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The conjunctiva that enricles the mesotibial spur and is encircled by the mesotibia." [] {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! conjunctiva relationship: AISM:0000078 AISM:0000434 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! encircles mesotibial spur relationship: AISM:0000079 AISM:0000068 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! encircled by mesotibia [Term] id: AISM:0000437 name: metatibio-metatibial spur conjunctiva {creation_date="2025-03-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The conjunctiva that enricles the metatibial spur and is encircled by the metatibia." [] {creation_date="2025-03-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-10"} ! conjunctiva relationship: AISM:0000078 AISM:0000435 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-10"} ! encircles metatibial spur relationship: AISM:0000079 AISM:0000069 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-10"} ! encircled by metatibia [Term] id: AISM:0000438 name: line connecting anterior margins of eyes {creation_date="2025-03-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The anatomical line parallel to the left-right body axis that is adjacent to the anterior margins of the eyes." [] {creation_date="2025-03-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} relationship: parallel_to BSPO:0000017 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-10"} ! left-right axis [Term] id: AISM:0000439 name: line connecting posterior margins of eyes {creation_date="2025-03-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The anatomical line parallel to the left-right body axis that is adjacent to the posterior margins of the eyes." [] {creation_date="2025-03-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} relationship: parallel_to BSPO:0000017 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-10"} ! left-right axis [Term] id: AISM:0000440 name: protarsus with 4 protarsomeres {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The protarsus with protarsomeres 1-4, without protarsomere 5." [] {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0004190 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-11"} ! protarsus relationship: BFO:0000051 AISM:0000302 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-11"} ! has part protarsomere 1 relationship: BFO:0000051 AISM:0000303 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-11"} ! has part protarsomere 2 relationship: BFO:0000051 AISM:0000304 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-11"} ! has part protarsomere 3 relationship: BFO:0000051 AISM:0000305 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-11"} ! has part protarsomere 4 [Term] id: AISM:0000441 name: protibial carina {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The tibial carina that is part of the protibia." [] {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000199 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-11"} ! tibial carina relationship: BFO:0000050 AISM:0000067 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-11"} ! part of protibia [Term] id: AISM:0000442 name: protibial anteroventral carina {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The protibial carina that is located in the antero-ventral region of the protibia." [] {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000441 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-11"} ! protibial carina [Term] id: AISM:0000443 name: protibial posteroventral carina {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The protibial carina that is located in the postero-ventral region of the protibia." [] {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000441 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-11"} ! protibial carina [Term] id: AISM:0000444 name: dorsal protibial margin proximal to protibial tooth 3 {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The anatomical margin part of the dorsal protibial margin that is proximal to dorsal protibial cuticular tooth 3 and distal to the profemoro-protibial conjunctiva." [] {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000374 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-11"} ! tibial margin relationship: BSPO:0000097 AISM:0004179 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-11"} ! distal to profemoro-protibial conjunctiva relationship: BSPO:0000100 AISM:0000370 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-11"} ! proximal to dorsal protibial cuticular tooth 3 [Term] id: AISM:0000445 name: line adjacent to mesotarsomeres 2-4 of mesotarsus with 5 mesotarsomeres {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The anatomical line parallel to the proximal-distal axis that is adjacent to: 1) the proximal margin of mesotarsomere 2 of mesotarsus with 5 mesotarsomeres; and 2) the distal margin of mesotarsomere 4 of mesotarsus with 5 mesotarsomeres." [] {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} relationship: BSPO:0001102 BSPO:0000015 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-11"} ! parallel to proximal-distal axis [Term] id: AISM:0000446 name: dorsal mesotibial spur {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The mesotibial spur that is located on the dorsal side of the tibial distal margin and is dorsal to the ventral protibial spur." [] {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} [Term] id: AISM:0000447 name: ventral mesotibial spur {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The mesotibial spur that is located on the ventral side of the tibial distal margin and is ventral to the dorsal protibial spur." [] {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} [Term] id: AISM:0000448 name: line adjacent to mesotarsomeres 2-5 of mesotarsus with 5 mesotarsomeres {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The anatomical line parallel to the proximal-distal axis that is adjacent to: 1) the proximal margin of mesotarsomere 2 of mesotarsus with 5 mesotarsomeres; and 2) the distal margin of mesotarsomere 5 of mesotarsus with 5 mesotarsomeres." [] {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} relationship: BSPO:0001102 BSPO:0000015 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-11"} ! parallel to proximal-distal axis [Term] id: AISM:0000449 name: line connecting medial margin of eyes {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The anatomical line parallel to the left-right body axis that is adjacent to the medial margins of the eyes." [] {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} relationship: parallel_to BSPO:0000017 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-11"} ! left-right axis [Term] id: AISM:0000450 name: membranous dorsodistal region of paramere {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The dorsodistal region of the cuticle of the paramere which has decreased thickness." [] {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000174 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-11"} ! insect region of cuticle relationship: RO:0000053 PATO:0000592 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-11"} ! has characteristic decreased thickness [Term] id: AISM:0000501 name: cuticular carina {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"an elevated ridge or keel, not necessarily high or acute\"", term:modified="2021-12-10"} def: "The protrusion on a sclerite that is linear." [] {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330", creation_date="2021-05-06"} is_a: AISM:0000008 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! cuticular protrusion relationship: BFO:0000050 AISM:0000003 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! part of insect sclerite relationship: RO:0000053 PATO:0001199 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! has characteristic linear [Term] id: AISM:0000523 name: dorsal postabdomen def: "Dorsal part of postabdomen." [] {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330", creation_date="2021-05-31"} is_a: AISM:0004057 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! abdominal tergite relationship: BFO:0000050 AISM:0004056 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! part of postabdomen [Term] id: AISM:0000524 name: cuticular puncture {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"a small impression on the cuticle\"", term:modified="2021-12-10"} def: "The cuticular fovea that is small." [] {term:modified="2021-12-10", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-07-21"} is_a: AISM:0000156 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! cuticular fovea relationship: RO:0000053 PATO:0000587 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! has characteristic decreased size [Term] id: AISM:0000525 name: cuticular granule {term:modified="2021-12-10", AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"a little grain or a minute grainlike elevation\"."} def: "The cuticular protrusion of a sclerite that is small and convex." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-07-21"} is_a: AISM:0000008 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! cuticular protrusion relationship: BFO:0000050 AISM:0000003 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! part of insect sclerite relationship: RO:0000053 PATO:0000587 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! has characteristic decreased size [Term] id: AISM:0000526 name: cuticular tubercle {term:modified="2021-12-10", AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"a small knoblike or rounded protuberance\""} def: "The cuticular protrusion of a sclerite that is rounded (circular)." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-07-21"} is_a: AISM:0000008 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! cuticular protrusion relationship: BFO:0000050 AISM:0000003 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! part of insect sclerite relationship: RO:0000053 PATO:0000411 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! has characteristic circular [Term] id: AISM:0000527 name: cuticular spine {AISM:0000171="Richards AG, Richards PA (1979) The cuticular protuberances of insects. International Journal of Insect Morphology and Embryology 8: 143–157. \n\n\"Multicellular protuberances without differentiation of specialized cells [...] evaginations, non-movable\"", source="https://doi.org/10.1016/0020-7322(79)90013-8", term:modified="2021-12-10"} def: "The cuticular protrusion of a sclerite that is pointed and narrow." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-07-21"} is_a: AISM:0000008 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! cuticular protrusion relationship: BFO:0000050 AISM:0000003 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! part of insect sclerite relationship: RO:0000053 PATO:0000599 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-06-20"} ! has characteristic decreased width relationship: RO:0000053 PATO:0002258 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! has characteristic pointed [Term] id: AISM:0000528 name: granulated cuticle {term:modified="2021-12-10", AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"covered with or made up of very small grains or granules\""} def: "The region of cuticle that bears an anatomical collection that is composed of granules." [] {term:modified="2021-12-10", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-07-21"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: BFO:0000051 UBERON:0034925 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! has part anatomical collection relationship: RO:0002351 AISM:0000525 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! has member cuticular granule [Term] id: AISM:0000529 name: punctate cuticle {term:modified="2021-12-10", AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"set with fine, impressed points or punctures appearing as pin-pricks\""} def: "The region of cuticle that bears an anatomical collection that is composed of punctures." [] {term:modified="20021-12-10", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-07-21"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: BFO:0000051 UBERON:0034925 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! has part anatomical collection relationship: RO:0002351 AISM:0000524 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! has member cuticular puncture [Term] id: AISM:0000530 name: setose cuticle {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"furnished or covered with setae or stiff hairs\"", term:modified="2021-12-10"} def: "The region of the cuticle that bears an anatomical collection that is composed of setae." [] {term:modified="2021-12-10", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-07-21"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: BFO:0000051 UBERON:0034925 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! has part anatomical collection relationship: RO:0002351 AISM:0000039 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! has member cuticular seta [Term] id: AISM:0000531 name: conjunctival keel def: "The cuticular evagination constituted by conjunctiva that is elongated." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-11-19"} is_a: AISM:0000027 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! cuticular evagination relationship: BFO:0000050 AISM:0000004 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! part of conjunctiva relationship: RO:0000053 PATO:0001154 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! has characteristic elongated [Term] id: AISM:0000532 name: conjunctival tubercle def: "The cuticular evagination constituted by conjunctiva that is circular." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-11-19"} is_a: AISM:0000027 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! cuticular evagination relationship: BFO:0000050 AISM:0000004 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! part of conjunctiva relationship: RO:0000053 PATO:0000411 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! has characteristic circular [Term] id: AISM:0000534 name: conjunctival fold def: "The cuticular depression constituted by conjunctiva that is elongated." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-11-19"} is_a: AISM:0000005 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular depression relationship: BFO:0000050 AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! part of conjunctiva relationship: RO:0000053 PATO:0001154 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! has characteristic elongated [Term] id: AISM:0002002 name: anterior tentorio-scapal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Anterior or dorsal tentorial arms\"\n\n\"Insertion: Anterior (ventral) basal margin of the scape\""} def: "The cranio-antennal muscle that is attached to the dorsal tentorial arm and the proximal margin of the scapus." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000081 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-antennal muscle relationship: RO:0002371 AISM:0004039 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to dorsal tentorial arm [Term] id: AISM:0002003 name: posterior tentorio-scapal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Anterior or dorsal tentorial arms\"\n\n\"Insertion: Posterior (dorsal) basal margin of the scape\""} def: "The cranio-antennal muscle that is attached to the dorsal or anterior tentorial arm and the proximo-dorsal margin of the scapus." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000081 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-antennal muscle [Term] id: AISM:0002004 name: lateral tentorio-scapal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Anterior or dorsal tentorial arms\"\n\n\"Insertion: Lateral basal margin of the scape\""} def: "The cranio-antennal muscle that extends between the dorsal or anterior tentorial arm and the proximo-lateral margin of the scapus." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000081 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-antennal muscle [Term] id: AISM:0002005 name: medial tentorio-scapal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Anterior or dorsal tentorial arms\"\n\n\"Insertion: Mesal basal margin of the scape\""} def: "The cranio-antennal muscle that is attached to the dorsal or anterior tentorial arm and the proximal margin of the scapus." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000081 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-antennal muscle relationship: RO:0002371 AISM:0004039 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to dorsal tentorial arm [Term] id: AISM:0002006 name: fronto-pedicellar muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Frons\"\n\n\"Insertion: Lateral edge of the pedicel\""} def: "The cranio-antennal muscle that is attached to the frons and the pedicellus." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000081 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-antennal muscle relationship: RO:0002371 AISM:0000115 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to pedicellus relationship: RO:0002371 AISM:0004020 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to frons [Term] id: AISM:0002007 name: lateral scapo-pedicellar muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Dorsal or dorsolateral wall of the scape\"\n\n\"Insertion: Lateral or dorsolateral wall of the pedicel\""} def: "The cranio-antennal muscle that is attached to the dorsal or dorsolateral regions of the scapus and the lateral or dorsolateral regions of the pedicellus." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000081 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-antennal muscle [Term] id: AISM:0002008 name: medial scapo-pedicellar muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Mesal or dorsomesal wall of the scape\"\n\n\"Insertion: Mesal, anteriomesal or anterior edge of the pedicel\""} def: "The cranio-antennal muscle that is attached to the scapus and the pedicellus." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000081 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-antennal muscle relationship: RO:0002371 AISM:0000113 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to scapus relationship: RO:0002371 AISM:0000115 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to pedicellus [Term] id: AISM:0002009 name: frontolabral muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Mesally on the frons or on the antennal base\"\n\n\"Insertion: Mesally on the outer basal wall of the labrum\""} def: "The cranio-labral muscle that is attached to the frons and the labrum." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000084 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-labral muscle relationship: RO:0002371 AISM:0004020 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to frons [Term] id: AISM:0002010 name: epistoepipharyngeal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Epistomal sulcus\"\n\n\"Insertion: Basal labral wall\""} def: "The cranio-labral muscle that is attached to the frontoclypeal ridge and the labrum." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000084 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-labral muscle relationship: RO:0002371 AISM:0004034 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to frontoclypeal ridge [Term] id: AISM:0002011 name: frontoepypharyngeal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Mesally on the frons or on the antennal base,\nusually on the same level as musculus\nfrontolabralis\"\n\n\"Insertion: Basal labral wall or tormae\""} def: "The cranio-labral muscle that is attached to the frons and the tormae." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000084 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-labral muscle relationship: RO:0002371 AISM:0002012 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to torma relationship: RO:0002371 AISM:0004020 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to frons [Term] id: AISM:0002012 name: torma {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Tormae: lateral apodemes of labral base\""} def: "The apodeme at either side of the proximal margin of the labrum." [] {creation_date="2021-04-22", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000188 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! apodeme [Term] id: AISM:0002013 name: transversal labral muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Ventral labral wall\"\n\n\"Insertion: Ventral labral wall of the other side\""} def: "The cranio-labral muscle that extends betwen the sides of the labrum." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000084 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-labral muscle [Term] id: AISM:0002014 name: internal cranio-mandibular muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Ventral, posterior, lateral and/or dorsal parts of\nthe head capsule and/or posterior and\nanterior tentorial arms\"\n\n\"Insertion: Tendon that inserts at the median edge of the\nmandible\""} def: "The cranio-mandibular muscle that is attached to the head capsule and the insect mandible." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000082 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-mandibular muscle [Term] id: AISM:0002017 name: posteroexternal cranio-mandibular muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Gena and postgena\"\n\n\"Insertion: Tendon that inserts at the lateral edge of the mandible\""} def: "The cranio-mandibular muscle that extends between the gena and the lateral margin of the insect mandible." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000082 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-mandibular muscle relationship: RO:0002371 AISM:0004026 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to gena [Term] id: AISM:0002018 name: anteroexternal cranio-mandibular muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Gena, below the compound eye\"\n\n\"Insertion: With a tendon on the mandible, posterior to the anterior articulation complex\""} def: "The cranio-mandibular muscle that is attached to the gena and the insect mandible." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000082 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-mandibular muscle relationship: RO:0002371 AISM:0004026 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to gena [Term] id: AISM:0002019 name: hypopharyngeal suspensorium {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043\n\n\"Suspensorium (=fulturae, hypopharyngeal arms, oral arms): sclerotized strengthening elements of proximal hypopharynx.\""} def: "The hypopharyngeal sclerite on the proximal region of the hypopharynx." [] {creation_date="2021-04-22", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", term:modified="2022-06-22"} synonym: "fulturae" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043"} synonym: "hypopharyngeal arms" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043"} synonym: "oral arms" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043"} is_a: AISM:0004275 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! hypopharyngeal sclerite [Term] id: AISM:0002021 name: hypopharyngeomandibular muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Small sclerite close to the loral arm\n(Thermobia), scleroticed arm that elongates\nthe loral arm (Neoptera)\"\n\n\"Insertion: Inner side of the lateral wall of the mandible\""} def: "The cranio-mandibular muscle that is attached to the suspensorium and the insect mandible." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000082 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-mandibular muscle relationship: RO:0002371 AISM:0002019 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to hypopharyngeal suspensorium [Term] id: AISM:0002022 name: superolateral tentorio-mandibular muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Anterior and dorsal tentorial arm\"\n\n\"Insertion: Outer basal edge of the mandibular body, between processus paratentorialis and posterior articulation\""} def: "The cranio-mandibular muscle that is attached to the dorsal tentorial arm and the proximal margin of the insect mandible." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000082 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-mandibular muscle relationship: RO:0002371 AISM:0004039 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to dorsal tentorial arm [Term] id: AISM:0002023 name: inferolateral tentorio-mandibular muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Anterior tentorial arm\"\n\n\"Insertion: Ventral basal margin of the mandible\""} def: "The cranio-mandibular muscle that extends between the anterior tentorial arm and the proximal-ventral margin of the insect mandible." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000082 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-mandibular muscle relationship: RO:0002371 AISM:0004038 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to anterior tentorial arm [Term] id: AISM:0002024 name: superomedial tentorio-mandibular muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Anterior and dorsal tentorial arm below musculus tentoriomandibularis externus dorsalis\"\n\n\"Insertion: Upper inner end of the mandible, just below the posterior mandibular condyle\""} def: "The cranio-mandibular muscle that is attached to the anterior tentorial arm and the insect mandible." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000082 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-mandibular muscle relationship: RO:0002371 AISM:0004038 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to anterior tentorial arm [Term] id: AISM:0002025 name: inferomedial tentorio-mandibular muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Anterior tentorial arm, below musculus tentoriomandibularis lateralis superior\"\n\n\"Insertion: Mediodorsal wall of the mandibular cavity\""} def: "The cranio-mandibular muscle that extends between the anterior tentorial arm and the dorso-medial region of the insect mandible." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000082 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-mandibular muscle relationship: RO:0002371 AISM:0004038 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to anterior tentorial arm [Term] id: AISM:0002026 name: insect cranio-maxillar muscle def: "The somatic muscle that is attached to the head capsule and the insect maxilla." [] {creation_date="2021-04-04", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932", term:modified="2021-12-13"} is_a: UBERON:0014895 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932", term:modified="2021-12-13"} ! somatic muscle, invertebrate relationship: RO:0002371 AISM:0000044 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to insect maxilla [Term] id: AISM:0002027 name: cranio-cardinal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Postgena and gena\"\n\n\"Insertion: Basal cardinal process\""} def: "The insect cranio-maxillar muscle that is attached to the gena and the cardo." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0002026 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranio-maxillar muscle relationship: RO:0002371 AISM:0000018 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to cardo relationship: RO:0002371 AISM:0004026 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to gena [Term] id: AISM:0002028 name: cranio-lacinial muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Posterior part of the gena\"\n\n\"Insertion: Basal edge of lacinia\""} def: "The insect cranio-maxillar muscle that is attached to the gena and the lacinia." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0002026 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranio-maxillar muscle relationship: RO:0002371 AISM:0000026 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to lacinia relationship: RO:0002371 AISM:0004026 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to gena [Term] id: AISM:0002029 name: tentorio-cardinal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Tentorium\"\n\n\"Insertion: Distal part of the cardo, close to the carostipital\nsulcus\""} def: "The insect cranio-maxillar muscle that is attached to the tentorium and the cardo." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0002026 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranio-maxillar muscle relationship: RO:0002371 AISM:0000018 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to cardo relationship: RO:0002371 AISM:0000191 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to tentorium [Term] id: AISM:0002030 name: anterior tentorio-stipital muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Tentorium\"\n\n\"Insertion: Stipital ridge\""} def: "The insect cranio-maxillar muscle that is attached to the tentorium and the stipital ridge." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0002026 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranio-maxillar muscle relationship: RO:0002371 AISM:0000191 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to tentorium relationship: RO:0002371 AISM:0002031 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to stipital ridge [Term] id: AISM:0002031 name: stipital ridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043"} def: "The ridge that is part of the stipes." [] {creation_date="2021-04-22", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000158 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cuticular ridge relationship: BFO:0000050 AISM:0000111 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! part of stipes [Term] id: AISM:0002032 name: posterior tentorio-stipital muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Tentorium\"\n\n\"Insertion: Basally on the stipes, close to the stipitocardinal\nsuture\""} def: "The insect cranio-maxillar muscle that is attached to the tentorium and the stipes." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0002026 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranio-maxillar muscle relationship: RO:0002371 AISM:0000111 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to stipes relationship: RO:0002371 AISM:0000191 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to tentorium [Term] id: AISM:0002033 name: stipito-lacinial muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Lateral wall of the stipes, basal to the maxillary\npalpus\"\n\n\"Insertion: Basal edge of lacinia, in some cases common\ntendon with 0mx4\""} def: "The insect cranio-maxillar muscle that is attached to the stipes and the lacinia." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0002026 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranio-maxillar muscle relationship: RO:0002371 AISM:0000026 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to lacinia relationship: RO:0002371 AISM:0000111 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to stipes [Term] id: AISM:0002034 name: stipito-galeal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Lateral wall of the stipes, basal to the maxillary\npalpus\"\n\n\"Insertion: Basal edge of galea\""} def: "The insect cranio-maxillar muscle that is attached to the stipes and the galea." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0002026 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranio-maxillar muscle relationship: RO:0002371 AISM:0000023 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to galea relationship: RO:0002371 AISM:0000111 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to stipes [Term] id: AISM:0002035 name: stipito-palpal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x"} def: "The insect cranio-maxillar muscle that is attached to the stipes and the maxillary palpus." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0002026 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranio-maxillar muscle relationship: RO:0002371 AISM:0000051 {def="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to maxillary palpus relationship: RO:0002371 AISM:0000111 {def="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to stipes [Term] id: AISM:0002036 name: maxillary palpomere {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the mere that is part of the maxillary palpus." [] {term:modified="2021-12-08", creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000073 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mere relationship: BFO:0000050 AISM:0000051 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of maxillary palpus property_value: IAO:0000589 "cuticle of maxillary palpomere" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0002037 name: maxillary palpomere I {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the maxillary palpomere that is attached to the distal margin of the palpiger and to the proximal margin of the maxillary palpomere II." [] {term:modified="2021-12-08", creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0002036 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! maxillary palpomere relationship: AISM:0000079 AISM:0004017 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by palpigero-palpal conjunctiva property_value: IAO:0000589 "cuticle of maxillary palpomere I" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0002038 name: maxillary palpomere II {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the maxillary palpomere that is attached to the distal margin of the maxillary palpomere I." [] {term:modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0002036 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! maxillary palpomere property_value: IAO:0000589 "cuticle of maxillary palpomere II" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0002039 name: maxillary palpomere III {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the maxillary palpomere that is attached to the distal margin of the maxillary palpomere II." [] {term:modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0002036 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! maxillary palpomere property_value: IAO:0000589 "cuticle of maxillary palpomere III" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0002040 name: maxillary palpomere IV {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the maxillary palpomere that is attached to the distal margin of the maxillary palpomere III." [] {term:modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0002036 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! maxillary palpomere property_value: IAO:0000589 "cuticle of maxillary palpomere IV" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0002041 name: maxillary palpomere V {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the maxillary palpomere that is attached to the distal margin of the maxillary palpomere IV." [] {term:modified="2021-12-08", creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0002036 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! maxillary palpomere property_value: IAO:0000589 "cuticle of maxillary palpomere V" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0002042 name: first maxillar palpopalpal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Basal edge of palpomere 1\"\n\n\"Insertion: Basal edge of palpomere 2\""} def: "The insect cranio-maxillar muscle that is attached to the first maxillar palpomere and the second maxillar palpomere." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0002026 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranio-maxillar muscle relationship: RO:0002371 AISM:0002037 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to maxillary palpomere I relationship: RO:0002371 AISM:0002038 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to maxillary palpomere II [Term] id: AISM:0002043 name: second maxillar palpopalpal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Mesal edge of palpomere 2\"\n\n\"Insertion: Mesal edge of palpomere 3\""} def: "The insect cranio-maxillar muscle that is attached to the second maxillar palpomere and the third maxillar palpomere." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0002026 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranio-maxillar muscle relationship: RO:0002371 AISM:0002038 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to maxillary palpomere II relationship: RO:0002371 AISM:0002039 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to maxillary palpomere III [Term] id: AISM:0002044 name: third maxillar palpopalpal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Basal edge of palpomere 3\"\n\n\"Insertion: Basal edge of palpomere 4\""} def: "The insect cranio-maxillar muscle that is attached to the third maxillar palpomere and the fourth maxillar palpomere." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0002026 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranio-maxillar muscle relationship: RO:0002371 AISM:0002039 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to maxillary palpomere III relationship: RO:0002371 AISM:0002040 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to maxillary palpomere IV [Term] id: AISM:0002045 name: fourth maxillar palpopalpal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Mesal edge of palpomere 4\"\n\n\"Insertion: Mesal edge of palpomere 5\""} def: "The insect cranio-maxillar muscle that is attached to the fourth maxillar palpomere and the fifth maxillar palpomere." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0002026 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranio-maxillar muscle relationship: RO:0002371 AISM:0002040 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to maxillary palpomere IV relationship: RO:0002371 AISM:0002041 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to maxillary palpomere V [Term] id: AISM:0002047 name: postoccipitoglossal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Postoccipital phragma\"\n\n\"Insertion: glossa\""} def: "The cranio-labial muscle that is attached to the postoccipital phragma and the glossa." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000083 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-labial muscle relationship: RO:0002371 AISM:0000049 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to glossa relationship: RO:0002371 AISM:0002049 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to postoccipital phragma [Term] id: AISM:0002048 name: phragma {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043\n\n\"Phragma: large, ridge-shaped internal apodeme.\"\n\n\"Phragma (=antecosta): dorsal thoracic transverse ridge, attachment site of dorsal longitudinal indirect flight muscles.\" (p. 121)"} def: "The internal apodeme that is continuous with the cuticle of the notum and is attached to a dorsal longitudinal muscle." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000188 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! apodeme is_a: UBERON:0000061 ! anatomical structure relationship: RO:0002150 AISM:0004128 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! continuous with notum relationship: RO:0002150 UBERON:0001002 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! continuous with cuticle relationship: RO:0002371 AISM:0002066 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! attached to dorsal longitudinal thoracic muscle [Term] id: AISM:0002049 name: postoccipital phragma {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x"} def: "The phragma that is continuous with the postocciput." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0002048 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! phragma relationship: RO:0002150 AISM:0004045 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with postocciput [Term] id: AISM:0002050 name: postoccipitopremental muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Postoccipital phragma, laterad to musculus\npostoccipitoparaglossalis\"\n\n\"Insertion: Posteriolateral angle of the prementum\""} def: "The cranio-labial muscle that is attached to the postoccipital phragma and the prementum." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000083 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-labial muscle relationship: RO:0002371 AISM:0000057 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to prementum relationship: RO:0002371 AISM:0002049 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to postoccipital phragma [Term] id: AISM:0002051 name: tentorio-premental muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Posterior tentorial arms, cranium\"\n\n\"Insertion: Laterobasal edge of prementum\""} def: "The cranio-labial muscle that is attached to the posterior tentorial arm and the prementum." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000083 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-labial muscle relationship: RO:0002371 AISM:0000057 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to prementum relationship: RO:0002371 AISM:0004037 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to posterior tentorial arm [Term] id: AISM:0002052 name: tentorio-paraglossal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Posterior tentorial arms, postoccipital ridge or\ncranium\"\n\n\"Insertion: Paraglossa, close to the labial palp\""} def: "The cranio-labial muscle that is attached to the posterior tentorial arm and the paraglossa." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000083 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-labial muscle relationship: RO:0002371 AISM:0000050 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to paraglossa relationship: RO:0002371 AISM:0004037 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to posterior tentorial arm [Term] id: AISM:0002053 name: submentopremental muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Mediobasal part of submentum or gula\"\n\n\"Insertion: Mediobasal edge of prementum, close to the gales\""} def: "The cranio-labial muscle that is attached to the submentum and the prementum." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000083 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-labial muscle relationship: RO:0002371 AISM:0000057 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to prementum relationship: RO:0002371 AISM:0004005 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to submentum [Term] id: AISM:0002054 name: submentomental muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: submentum\"\n\n\"Insertion: mentum\""} def: "The cranio-labial muscle that is attached to the submentum and the mentum." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000083 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-labial muscle relationship: RO:0002371 AISM:0004004 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to insect mentum relationship: RO:0002371 AISM:0004005 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to submentum [Term] id: AISM:0002055 name: premento-paraglossal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Mesal on the basal edge of the prementum\"\n\n\"Insertion: Dorsobasal edge of paraglossa\""} def: "The cranio-labial muscle that is attached to the prementum and the paraglossa." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000083 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-labial muscle relationship: RO:0002371 AISM:0000050 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to paraglossa relationship: RO:0002371 AISM:0000057 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to prementum [Term] id: AISM:0002056 name: premento-glossal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Mesally on the prementum\"\n\n\"Insertion: Mediobasal edge of glossa\""} def: "The cranio-labial muscle that is attached to the prementum and the glossa." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000083 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-labial muscle relationship: RO:0002371 AISM:0000049 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to glossa relationship: RO:0002371 AISM:0000057 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to prementum [Term] id: AISM:0002057 name: premento-palpal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: prementum\"\n\n\"Insertion: labial palpus\""} def: "The cranio-labial muscle that is attached to the prementum and the labial palpus." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000083 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-labial muscle relationship: RO:0002371 AISM:0000024 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to labial palpus relationship: RO:0002371 AISM:0000057 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to prementum [Term] id: AISM:0002058 name: cranio-hypopharyngeal muscle def: "The somatic muscle that is attached to the head capsule and the hypopharynx." [] {creation_date="2021-04-04", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932", term:modified="2021-12-13"} is_a: AISM:0000080 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranial muscle relationship: RO:0002371 AISM:0000093 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to hypopharynx [Term] id: AISM:0002059 name: fronto-oral muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Frons\"\n\n\"Insertion: Oral arms of the suspensorial sclerites\""} def: "The cranio-hypopharyngeal muscle that is attached to the frons and the suspensorium." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0002058 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-hypopharyngeal muscle relationship: RO:0002371 AISM:0002019 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to hypopharyngeal suspensorium relationship: RO:0002371 AISM:0004020 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to frons [Term] id: AISM:0002060 name: tentorio-oral muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Anterior tentorial arm, epistomal sulcus or\nfrons close to epistomal sulcus\"\n\n\"Insertion: Oral arms of the suspensorial sclerites, well\nseperated from above\""} def: "The cranio-hypopharyngeal muscle that is attached to the anterior tentorial arm and the suspensorium." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0002058 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-hypopharyngeal muscle relationship: RO:0002371 AISM:0002019 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to hypopharyngeal suspensorium relationship: RO:0002371 AISM:0004038 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to anterior tentorial arm [Term] id: AISM:0002061 name: insect cranio-tentorial muscle def: "The somatic muscle that is attached to the head capsule and the tentorium." [] {creation_date="2021-04-04", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932", term:modified="2021-12-13"} is_a: UBERON:0014895 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932", term:modified="2021-12-13"} ! somatic muscle, invertebrate relationship: RO:0002371 AISM:0000191 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to tentorium [Term] id: AISM:0002062 name: tentorio-frontal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Laterad on the anterior corpotentorium\"\n\n\"Insertion: Frons\""} def: "The insect cranio-antennal muscle that is attached to the tentorial bridge and the frons." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0002061 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranio-tentorial muscle relationship: RO:0002371 AISM:0004020 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to frons relationship: RO:0002371 AISM:0004024 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to tentorial bridge [Term] id: AISM:0002063 name: tentorio-tentorial muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Ventrolaterad on the anterior corpotentorium\"\n\n\"Insertion: Mesad on the posterior tentorium\""} def: "The insect cranio-antennal muscle that is attached to the tentorial bridge and the tentorium." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0002061 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranio-tentorial muscle relationship: RO:0002371 AISM:0004024 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to tentorial bridge [Term] id: AISM:0002064 name: insect leg muscle def: "The somatic muscle that is part of the insect leg." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", term:modified="2021-12-13"} is_a: AISM:0002065 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect thoracic muscle relationship: BFO:0000050 AISM:0000031 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect leg [Term] id: AISM:0002065 name: insect thoracic muscle def: "The somatic muscle that is part of the insect thorax." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", term:modified="2021-12-13"} is_a: UBERON:0014895 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! somatic muscle, invertebrate relationship: BFO:0000050 AISM:0000108 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect thorax [Term] id: AISM:0002066 name: dorsal longitudinal thoracic muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003"} def: "The insect thoracic muscle that is not fan-shaped and runs along the dorsal region, parallel to the anterior-posterior axis." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0002065 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect thoracic muscle relationship: BFO:0000050 BSPO:0000079 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! part of dorsal region relationship: parallel_to BSPO:0000013 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! anterior-posterior axis [Term] id: AISM:0002067 name: dorso-ventral thoracic muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003"} def: "The insect thoracic muscle that runs parallel to the dorsal-ventral axis." [] {creation_date="2021-04-22", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0002065 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect thoracic muscle relationship: parallel_to BSPO:0000016 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! dorsal-ventral axis [Term] id: AISM:0002068 name: tergo-pleural muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003"} def: "The insect thoracic muscle that extends between the notum (or tergum) and the pleura." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0002065 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect thoracic muscle relationship: RO:0002150 AISM:0004129 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with pleuron relationship: RO:0002371 AISM:0004128 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! attached to notum [Term] id: AISM:0002069 name: sterno-pleural muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003"} def: "The insect thoracic muscle that extends between the sternum and the pleura." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0002065 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect thoracic muscle relationship: RO:0002371 AISM:0004129 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! attached to pleuron relationship: RO:0002371 AISM:0004130 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! attached to sternum [Term] id: AISM:0002070 name: ventral-longitudinal muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003"} def: "The insect thoracic muscle that is not fan-shaped and runs along the ventral region, parallel to the anterior-posterior axis." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0002065 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect thoracic muscle relationship: BFO:0000050 BSPO:0000084 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! part of ventral region relationship: parallel_to BSPO:0000013 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! anterior-posterior axis [Term] id: AISM:0002071 name: prophragma-occipital muscle {def="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003\n\n\"origin: prophragma\"\n\"insertion: postocciput\""} def: "The dorsal longitudinal thoracic muscle that is attached to the prophragma and the postocciput." [] {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932", creation_date="2021-04-06"} is_a: AISM:0002066 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! dorsal longitudinal thoracic muscle relationship: RO:0002371 AISM:0002076 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to prophragma relationship: RO:0002371 AISM:0004045 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to postocciput [Term] id: AISM:0002072 name: pronoto-occipital muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003\n\n\"origin: pronotum\"\n\n\"insertion: postocciput\""} def: "The dorsal longitudinal thoracic muscle that is attached to the pronotum and the postocciput." [] {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932", creation_date="2021-04-06"} is_a: AISM:0002066 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! dorsal longitudinal thoracic muscle relationship: RO:0002371 AISM:0000059 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to pronotum relationship: RO:0002371 AISM:0004045 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to postocciput [Term] id: AISM:0002073 name: prophragma-cervical muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003\n\n\"origin: prophragma\"\n\"insertion: cervical sclerite\""} def: "The dorsal longitudinal thoracic muscle that is attached to the prophragma and the cervical sclerite." [] {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932", creation_date="2021-04-06"} is_a: AISM:0002066 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! dorsal longitudinal thoracic muscle relationship: RO:0002371 AISM:0002076 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to prophragma relationship: RO:0002371 AISM:0004141 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to cervical sclerite [Term] id: AISM:0002074 name: dorsal cervico-occipital muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003\n\n\"origin: cervical sclerite\"\n\n\"insertion: postocciput\""} def: "The dorsal longitudinal thoracic muscle that is attached to the cervical sclerite and the postocciput." [] {creation_date="2021-04-04", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0002066 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! dorsal longitudinal thoracic muscle relationship: RO:0002371 AISM:0004045 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to postocciput relationship: RO:0002371 AISM:0004141 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to cervical sclerite [Term] id: AISM:0002075 name: pronoto-phragmal muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003\n\n\"origin: pronotum\"\n\"insertion: prophragma\""} def: "The dorsal longitudinal thoracic muscle that is attached to the pronotum and the prophragma." [] {creation_date="2021-04-04", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0002066 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! dorsal longitudinal thoracic muscle relationship: RO:0002371 AISM:0000059 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to pronotum relationship: RO:0002371 AISM:0002076 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! attached to prophragma [Term] id: AISM:0002076 name: prophragma def: "The phragma of the mesonotum that attaches to muscles attached to the pronotum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0002048 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! phragma relationship: BFO:0000050 AISM:0000052 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! part of mesonotum [Term] id: AISM:0002078 name: anterior cervico-occipital muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003\n\n\"The dorsoventral muscle that arises from dorsolateral postocciput and inserts on anterior tip of first lateral cervical sclerite.\""} def: "The dorsoventral thoracic muscle of the prothorax that is attached to the anterior margin of a cervical sclerite and the dorso-lateral region of the postocciput." [] {creation_date="2021-04-22", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0002067 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! dorso-ventral thoracic muscle relationship: BFO:0000050 AISM:0004125 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! part of prothorax [Term] id: AISM:0002079 name: anterior pronoto-cervical muscle {def="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003\n\n\"The dorsoventral muscle that arises from anterolateral pronotum and inserts on atypically on middle region of anterior propleural sclerite.\""} def: "The dorsoventral thoracic muscle that extends between the antero-lateral region of the pronotum and the medial region of the propleuron." [] {creation_date="2021-04-22", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0002067 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! dorso-ventral thoracic muscle [Term] id: AISM:0002080 name: prophragma-tentorial muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003"} def: "The dorsoventral thoracic muscle that extends between the tentorium and the prophragma." [] {creation_date="2021-04-22", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0002067 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! dorso-ventral thoracic muscle relationship: RO:0002371 AISM:0000191 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! attached to tentorium relationship: RO:0002371 AISM:0002076 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! attached to prophragma [Term] id: AISM:0002081 name: profurca-prophragmal muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003\n\n\"The dorsoventral muscle that arises from posterior face of proximal profurcal arm and inserts on lateral prophragma.\""} def: "The dorsoventral thoracic muscle that extends between the profurca and the lateral region of the prophragma." [] {creation_date="2021-04-22", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0002067 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! dorso-ventral thoracic muscle relationship: RO:0002371 AISM:0000143 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! attached to profurca [Term] id: AISM:0002082 name: profurca-occipital muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003"} def: "The dorsoventral thoracic muscle that extends between the posterior region (occipital region) of the head capsule and the profurca." [] {creation_date="2021-04-22", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0002067 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! dorso-ventral thoracic muscle relationship: RO:0002371 AISM:0000143 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! attached to profurca [Term] id: AISM:0002083 name: prophragma-mesophragmal muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003\n\n\"The dorsal longitudinal muscle that arises from median prophragma and inserts on median mesophragma.\""} def: "The dorsal longitudinal thoracic muscle that extends between the medial region of the prophragma and the medial region of the mesophragma." [] {creation_date="2021-04-22", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0002066 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! dorsal longitudinal thoracic muscle [Term] id: AISM:0002084 name: profurca-mesonotal muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003"} def: "The dorsoventral thoracic muscle that extends between the profurca and the mesonotum." [] {creation_date="2021-04-22", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0002067 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! dorso-ventral thoracic muscle relationship: RO:0002371 AISM:0000052 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! attached to mesonotum relationship: RO:0002371 AISM:0000143 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! attached to profurca [Term] id: AISM:0002085 name: insect abdominal muscle def: "The somatic muscle that is part of the insect abdomen." [] {creation_date="2021-04-22", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: UBERON:0014895 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932", term:modified="2021-12-13"} ! somatic muscle, invertebrate relationship: BFO:0000050 AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect abdomen [Term] id: AISM:0002086 name: lateral abdominal muscle {AISM:0000171="Klug, R., & Bradler, S. (2006). The pregenital abdominal musculature in phasmids and its implications for the basal phylogeny of Phasmatodea (Insecta: Polyneoptera). \nOrganisms Diversity & Evolution, 6(3), 171-184.\n\nhttps://doi.org/10.1016/j.ode.2005.08.004"} def: "The insect abdominal muscle that runs along the lateral region, parallel to the dorsal-ventral axis." [] {creation_date="2021-04-22", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0002085 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect abdominal muscle relationship: BFO:0000050 BSPO:0000082 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of lateral region relationship: parallel_to BSPO:0000016 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! dorsal-ventral axis [Term] id: AISM:0002087 name: ventral longitudinal abdominal muscle {AISM:0000171="Klug, R., & Bradler, S. (2006). The pregenital abdominal musculature in phasmids and its implications for the basal phylogeny of Phasmatodea (Insecta: Polyneoptera). \nOrganisms Diversity & Evolution, 6(3), 171-184.\n\nhttps://doi.org/10.1016/j.ode.2005.08.004"} def: "The insect abdominal muscle that runs along the ventral region, parallel to the anterior-posterior axis." [] {creation_date="2021-04-22", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0002085 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect abdominal muscle relationship: BFO:0000050 BSPO:0000084 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of ventral region relationship: parallel_to BSPO:0000013 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anterior-posterior axis [Term] id: AISM:0002088 name: dorsal longitudinal abdominal muscle {AISM:0000171="Klug, R., & Bradler, S. (2006). The pregenital abdominal musculature in phasmids and its implications for the basal phylogeny of Phasmatodea (Insecta: Polyneoptera). \nOrganisms Diversity & Evolution, 6(3), 171-184.\n\nhttps://doi.org/10.1016/j.ode.2005.08.004"} def: "The insect abdominal muscle that runs along the dorsal region, parallel to the anterior-posterior axis." [] {creation_date="2021-04-22", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0002085 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdominal muscle relationship: BFO:0000050 BSPO:0000079 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of dorsal region relationship: parallel_to BSPO:0000013 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anterior-posterior axis [Term] id: AISM:0004001 name: palpifer {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043\n\n\"Palpifer: small separate element of stipes, bears the maxillary palp.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The sclerite of the insect maxilla that is attached to the cuticle of stipes by the stipito-palpiferal conjunctiva and to the cuticle of maxillary palpus by the palpifero-palpal conjunctiva." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-17"} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: BFO:0000050 AISM:0000044 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect maxilla relationship: RO:0002150 AISM:0004010 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with stipito-palpiferal conjunctiva relationship: RO:0002150 AISM:0004012 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with palpifero-palpal conjunctiva relationship: RO:0002220 AISM:0000051 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to maxillary palpus relationship: RO:0002220 AISM:0000111 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to stipes property_value: IAO:0000589 "cuticle of palpifer" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004002 name: mental-premental conjunctiva def: "The conjunctiva of the labium that connects the mentum and the prementum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-17"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: BFO:0000050 AISM:0000087 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of labium relationship: RO:0002150 AISM:0000057 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with prementum relationship: RO:0002150 AISM:0004004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with insect mentum [Term] id: AISM:0004003 name: postmentum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Postmentum: posterior main element of labium, posteriorly adjacent with foramen occipitale in hexapods without gula or hypostomal bridge; often separated into two sclerites, the anterior mentum and the posterior submentum.\""} def: "The sclerite of the cuticle of labium that is cmposed of the submentum and the mentum, which are connected by the submental-mental conjunctiva" [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-17"} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: BFO:0000050 AISM:0000087 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of labium relationship: BFO:0000051 AISM:0004004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part insect mentum relationship: BFO:0000051 AISM:0004005 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part submentum relationship: BFO:0000051 AISM:0004013 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part submental-mental conjunctiva [Term] id: AISM:0004004 name: insect mentum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Mentum: intermediate part of labium, anterior part of postmentum; bears the prementum at its distal edge.\"", IAO:0000232="Modified 2023-01-20: to specify insect mentum.\njgiron https://orcid.org/0000-0002-0851-6883"} def: "The sclerite of the labium that is anterior to the submentum and posterior to the prementum, and attached to the prementum by the mental-premental conjunctiva." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-17"} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: BFO:0000050 AISM:0000087 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of labium relationship: BSPO:0000096 AISM:0004005 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anterior to submentum relationship: BSPO:0000099 AISM:0000057 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! posterior to prementum relationship: RO:0002150 AISM:0004002 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with mental-premental conjunctiva relationship: RO:0002220 AISM:0000057 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to prementum [Term] id: AISM:0004005 name: submentum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Submentum: posterior part of a divided postmentum.\""} def: "The sclerite of the labium that is anteriorly attached to the mentum by the submental-mental conjunctiva." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-17"} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: BFO:0000050 AISM:0000087 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of labium relationship: BSPO:0000099 AISM:0004004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! posterior to insect mentum relationship: RO:0002150 AISM:0004013 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with submental-mental conjunctiva [Term] id: AISM:0004006 name: palpiger {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043\n\n\"Palpiger: small separate element of prementum, bears the labial palp.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The sclerite of the cuticle of labium that is attached to the prementum by the premental-palpigeral conjunctiva and to the cuticle of labial palpus by the palpigero-palpal conjunctiva." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-17"} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: BFO:0000050 AISM:0000087 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of labium relationship: RO:0002150 AISM:0004014 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with premental-palpigeral conjunctiva relationship: RO:0002150 AISM:0004017 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with palpigero-palpal conjunctiva relationship: RO:0002220 AISM:0000024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to labial palpus relationship: RO:0002220 AISM:0000057 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to prementum property_value: IAO:0000589 "cuticle of palpiger" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004007 name: antenniferal-scapal conjunctiva def: "The conjunctiva of the head capsule that connects the antennifer and the scapus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: AISM:0000078 AISM:0000113 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles scapus relationship: BFO:0000050 AISM:0000112 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of cranio-antennal conjunctiva relationship: RO:0002150 AISM:0000190 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with antennifer [Term] id: AISM:0004008 name: interflagellomeral conjunctiva def: "Is the conjunctiva of the antenna that connects a flagellomere and other flagellomere." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000102 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! ring conjunctiva relationship: AISM:0000078 AISM:0000116 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles flagellomere relationship: AISM:0000079 AISM:0000116 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by flagellomere relationship: BFO:0000050 AISM:0000032 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of antenna [Term] id: AISM:0004009 name: stipito-lacinial conjunctiva def: "The conjunctiva of the insect maxilla that connects the stipes and the lacinia." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: BFO:0000050 AISM:0000044 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect maxilla relationship: RO:0002150 AISM:0000026 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with lacinia relationship: RO:0002150 AISM:0000111 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with stipes [Term] id: AISM:0004010 name: stipito-palpiferal conjunctiva def: "The conjunctiva of the insect maxilla that connects the stipes and the palpifer." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: BFO:0000050 AISM:0000044 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect maxilla relationship: RO:0002150 AISM:0000111 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with stipes relationship: RO:0002150 AISM:0004001 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with palpifer [Term] id: AISM:0004011 name: stipito-galeal conjunctiva def: "The conjunctiva of the insect maxilla that connects the stipes and the galea." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: BFO:0000050 AISM:0000044 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect maxilla relationship: RO:0002150 AISM:0000023 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with galea relationship: RO:0002150 AISM:0000111 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with stipes [Term] id: AISM:0004012 name: palpifero-palpal conjunctiva def: "The conjunctiva of the insect maxilla that connects the palpifer and the maxillary palpus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: BFO:0000050 AISM:0000044 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect maxilla relationship: RO:0002150 AISM:0000051 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with maxillary palpus relationship: RO:0002150 AISM:0004001 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with palpifer [Term] id: AISM:0004013 name: submental-mental conjunctiva def: "The conjunctiva of the labium that connects the submentum and the mentum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: BFO:0000050 AISM:0000087 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of labium relationship: RO:0002150 AISM:0004004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with insect mentum relationship: RO:0002150 AISM:0004005 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with submentum [Term] id: AISM:0004014 name: premental-palpigeral conjunctiva def: "The conjunctiva of the labium that connects the prementum and the palpiger." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: BFO:0000050 AISM:0000087 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of labium relationship: RO:0002150 AISM:0000057 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with prementum relationship: RO:0002150 AISM:0004006 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with palpiger [Term] id: AISM:0004015 name: premental-paraglossal conjunctiva def: "The conjunctiva of the labium that connects the prementum and the paraglossa." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: BFO:0000050 AISM:0000087 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of labium relationship: RO:0002150 AISM:0000050 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with paraglossa relationship: RO:0002150 AISM:0000057 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with prementum [Term] id: AISM:0004016 name: premental-glossal conjunctiva def: "The conjunctiva of the labium that connects the prementum and the glossa." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: BFO:0000050 AISM:0000087 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of labium relationship: RO:0002150 AISM:0000049 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with glossa relationship: RO:0002150 AISM:0000057 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with prementum [Term] id: AISM:0004017 name: palpigero-palpal conjunctiva def: "The conjunctiva of the labium that connects the palpiger and the labial palpus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: BFO:0000050 AISM:0000087 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of labium relationship: RO:0002150 AISM:0000024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with labial palpus relationship: RO:0002150 AISM:0004006 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with palpiger [Term] id: AISM:0004018 name: clypeo-labral conjunctiva def: "The conjunctiva of the insect maxilla that connects the clypeus and the labrum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: RO:0002150 AISM:0000042 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with labrum relationship: RO:0002150 AISM:0004019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with clypeus [Term] id: AISM:0004019 name: clypeus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Clypeus: anteroventral part of head capsule; primarily separated from frons by transverse frontoclypeal strengthening ridge between anterior tentorial pits; usually bearing the labrum at its distal margin.\""} def: "The region of the head capsule that is anterior to the frons and is attached to the labrum by the clypeo-labral conjunctiva" [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: BFO:0000050 AISM:0000019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of head capsule relationship: BSPO:0000096 AISM:0004020 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anterior to frons relationship: RO:0002150 AISM:0004018 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with clypeo-labral conjunctiva relationship: RO:0002220 AISM:0000042 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to labrum [Term] id: AISM:0004020 name: frons {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Frons: frontal part of head capsule, delimited by ecdysial lines (frontal sutures); often triangular and bearing unpaired (median) ocellus.\""} def: "The region of cuticle of the head capsule that is located posterior to the clypeus and delimited by the frontal suture." [] {creation_date="2021-04-03", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: BFO:0000050 AISM:0000019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of head capsule relationship: BSPO:0000099 AISM:0004019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! posterior to clypeus relationship: RO:0002150 AISM:0004029 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with frontal suture [Term] id: AISM:0004021 name: postoccipital ridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Postoccipital ridge: strengthening ridge enclosing the foramen occipitale dorsally and laterally; also serving as muscle attachment area.\""} def: "The ridge along the dorsal and lateral regions of the head capsule that is adjacent to the foramen occipitale." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000158 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular ridge relationship: RO:0002220 AISM:0004023 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to foramen occipitale [Term] id: AISM:0004022 name: circumocular ridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Circumocular ridge: internal ridge enclosing compound eye.\""} def: "The ridge of the head capsule surrounding the eye cuticle." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000158 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular ridge relationship: AISM:0000078 AISM:0000088 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles eye cuticle relationship: BFO:0000050 AISM:0000019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of head capsule [Term] id: AISM:0004023 name: foramen occipitale {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Foramen occipitale (=foramen magnum): posterior opening of head capsule; divided by tentorial bridge into alaforamen and neuroforamen.\""} def: "The foramen of the head capsule that connects with the neck membrane and is divided by the tentorial bridge into alaforamen and neuroforamen." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} synonym: "occipital foramen" EXACT [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000197 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! arthropod foramen relationship: BFO:0000051 AISM:0004040 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part alaforamen relationship: BFO:0000051 AISM:0004041 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part neuroforamen relationship: RO:0002150 AISM:0000019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with head capsule relationship: RO:0002150 AISM:0000098 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with neck membrane relationship: RO:0002220 AISM:0004024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to tentorial bridge [Term] id: AISM:0004024 name: tentorial bridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Tentorial bridge (=corpotentorium): transverse element connecting posterior tentorial arms, often plate-like.\""} def: "The apophysis of the tentorium originating from each posterior tentorial arm." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} synonym: "corpotentorium" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Tentorial bridge (=corpotentorium): transverse element connecting posterior tentorial arms, often plate-like.\""} is_a: AISM:0000138 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular apophysis relationship: BFO:0000050 AISM:0000191 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of tentorium relationship: RO:0002150 AISM:0004037 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with posterior tentorial arm [Term] id: AISM:0004025 name: vertex {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Vertex: posterodorsal part of head capsule, usually medially divided by ecdysial line (coronal suture).\""} def: "The dorsal region of the head capsule that surrounds the coronal suture, and is connected laterally to the genae." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: AISM:0000078 AISM:0004030 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles coronal suture [Term] id: AISM:0004026 name: gena {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Gena: lateral region of head capsule; not separated from vertex by a ridge or suture.\""} def: "The lateral region of the head capsule, connected dorsally to the lateral regions of the vertex." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle [Term] id: AISM:0004027 name: subgena {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Subgena: narrow lateral region of head capsule, above external side of mandibular base, usually separated from gena by subgenal ridge.\""} def: "The lateral region of the head capsule that connects dorsally to the ventral side of the gena and ventrally to the mandible." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: RO:0002220 AISM:0000043 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to insect mandible [Term] id: AISM:0004028 name: cuticular suture {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Suture: ecdysial suture, zone of weakness.\"", term:modified="2021-12-10"} def: "The region of the cuticle of the head capsule that coincides with an ecdysial line." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: BFO:0000050 AISM:0000019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of head capsule relationship: RO:0002008 AISM:0004157 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! coincident with ecdysial line [Term] id: AISM:0004029 name: frontal suture {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Frontal suture: paired ecdysial sutures enclosing frons; anterior parts of epicranial suture.\""} def: "The cuticular suture that surrounds the frons and is connected to the coronal suture." [] {creation_date="2021-04-03", term:modified="2021-12-10", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004028 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular suture relationship: AISM:0000078 AISM:0004020 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles frons relationship: RO:0000053 PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has characteristic bilaterally paired relationship: RO:0002150 AISM:0004030 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with coronal suture [Term] id: AISM:0004030 name: coronal suture {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Coronal suture: unpaired median ecdysial sutures dividing vertex; anteriorly continuous with frontal sutures.\""} def: "The longitudinal cuticular suture that is on the vertex and is connected to the frontal suture." [] {creation_date="2021-04-03", term:modified="2021-12-10", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004028 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular suture relationship: AISM:0000079 AISM:0004025 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by vertex relationship: parallel_to BSPO:0000013 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anterior-posterior axis relationship: RO:0002150 AISM:0004029 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with frontal suture [Term] id: AISM:0004031 name: pleurostomal ridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n[Pleurostomal ridge: anterior section of the subgenal ridge above the mandibular base. (p. 14)]"} def: "The ridge of the head capsule comprising the posterior region of the subgenal ridge." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000158 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular ridge [Term] id: AISM:0004032 name: subgenal ridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Subgenal ridge: strengthening ridge separating gena from subgena.\""} def: "The ridge of the head capsule that separates the gena and the subgena." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000158 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular ridge relationship: BFO:0000050 AISM:0000019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of head capsule relationship: RO:0002220 AISM:0004026 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to gena relationship: RO:0002220 AISM:0004027 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to subgena [Term] id: AISM:0004033 name: hypostomal bridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Hypostomal bridge: partial closure of foramen occipitale, formed by ventromedially adjacent extensions of lateral head capsule.\"\n[posterior section of the subgenal ridge; p. 14]"} def: "The lateral region of the head capsule that is adjacent to the foramen occipitale" [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: BFO:0000050 AISM:0000019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of head capsule relationship: RO:0002220 AISM:0004023 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to foramen occipitale [Term] id: AISM:0004034 name: frontoclypeal ridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Frontoclypeal (strengthening) ridge (=frontoclypeal “suture”, epistomal “suture”): internal ridge separating clypeus from frons, between anterior tentorial pits.\""} def: "The ridge of the head capsule that separates the clypeus and the frons." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000158 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular ridge relationship: BFO:0000050 AISM:0000019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of head capsule relationship: RO:0002220 AISM:0004019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to clypeus relationship: RO:0002220 AISM:0004020 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to frons [Term] id: AISM:0004035 name: gula {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Gula: sclerite partially closing foramen occipitale, formed by sclerotized region of ventral cervical membrane.\""} def: "The sclerite on the ventral region of the head capsule that is limited laterally by the gular ridges, posteriorly by the foramen occipitale and anteriorly by the submentum." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: BSPO:0000096 AISM:0004023 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anterior to foramen occipitale relationship: BSPO:0000099 AISM:0004005 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! posterior to submentum relationship: RO:0002150 AISM:0004036 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with gular ridge [Term] id: AISM:0004036 name: gular ridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Gular ridges: lateral internal ridges enclosing the gula.\""} def: "Each ridge on the ventral region of the head capsule marking the sides of the gula." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000158 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular ridge [Term] id: AISM:0004037 name: posterior tentorial arm {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Posterior tentorial arm: paired posterior element of tentorium; originates at posterior tentorial pit.\""} def: "The apophysis of the tentorium that originates from each posterior tentorial pit." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000138 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular apophysis relationship: BFO:0000050 AISM:0000191 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of tentorium relationship: RO:0002150 AISM:0000195 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with posterior tentorial pit [Term] id: AISM:0004038 name: anterior tentorial arm {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043\n\n\"Anterior tentorial arm: paired tentorial element anterior to tentorial bridge; originates at anterior tentorial pit.\""} def: "The apophysis of the tentorium that is connected to an anterior tentorial pit." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000138 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular apophysis relationship: BFO:0000050 AISM:0000191 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of tentorium relationship: RO:0002150 AISM:0000194 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with anterior tentorial pit [Term] id: AISM:0004039 name: dorsal tentorial arm {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Dorsal tentorial arm: paired dorsal element of tentorium, originating at anterior arm or connecting area of anterior and posterior arm; often connected with head capsule by fibrillae.\""} def: "The apophysis of the tentorium that is connected to an anterior tentorial arm." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000138 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular apophysis relationship: BFO:0000050 AISM:0000191 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of tentorium relationship: RO:0002150 AISM:0004038 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with anterior tentorial arm [Term] id: AISM:0004040 name: alaforamen {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043\n\n\"Alaforamen: part of foramen occipitale above tentorial bridge; passage of oesophagus and tracheal stems.\""} def: "The arthropod foramen that is part of the foramen occipitale and is located above the tentorial bridge." [] {creation_date="2021-04-03", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000197 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! arthropod foramen relationship: BFO:0000050 AISM:0004023 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of foramen occipitale relationship: BSPO:0000098 AISM:0004024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! dorsal to tentorial bridge [Term] id: AISM:0004041 name: neuroforamen {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Neuroforamen: part of foramen occipitale below tentorial bridge; passage of cervical connectives between suboesophageal complex and prothoracic ganglion.\""} def: "The arthropod foramen that is part of the foramen occipitale and located below the tentorial bridge." [] {creation_date="2021-04-03", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000197 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! arthropod foramen relationship: BFO:0000050 AISM:0004023 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of foramen occipitale relationship: BSPO:0000102 AISM:0004024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! ventral to tentorial bridge [Term] id: AISM:0004042 name: postgena {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Postgena: posterior genal region anterior to postoccipital ridge.\""} def: "The posterior region of the head capsule that is continuous with the posterior region of the gena and is anterior to the postoccipital ridge." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle [Term] id: AISM:0004043 name: postgenal bridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Postgenal bridge: partial closure of foramen occipital formed by postgenal extensions.\""} def: "The region of the head capsule that is continuous with the postgena and adjacent to the foramen occipitale." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: BFO:0000050 AISM:0000019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of head capsule relationship: RO:0002150 AISM:0004042 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with postgena relationship: RO:0002220 AISM:0004023 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to foramen occipitale [Term] id: AISM:0004044 name: circumantennal ridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"The antennal foramen is enclosed by a circumantennal ridge, which often bears a small articulatory process, the antennifer.\""} def: "The ridge of the head capsule that encircles the antennal foramen." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000158 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular ridge relationship: AISM:0000078 AISM:0000198 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles antennal foramen relationship: BFO:0000050 AISM:0000019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of head capsule [Term] id: AISM:0004045 name: postocciput {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Postocciput: posteriormost head region.\""} def: "The dorsolateral region of the head capsule that is posterior to the postoccipital ridge" [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", term:modified="2022-06-17"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: BSPO:0000099 AISM:0004021 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-17"} ! posterior to postoccipital ridge [Term] id: AISM:0004046 name: hypostoma {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Hypostoma: posterior part of subgena.\""} def: "The region of the head capsule that comprises the posterior region of the subgena." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle [Term] id: AISM:0004047 name: hypostomal ridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Hypostomal ridge: posterior part of subgenal ridge.\""} def: "The ridge composing the posterior region of the subgenal ridge." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000158 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular ridge [Term] id: AISM:0004048 name: occipital ridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Occipital ridge (=“occipital suture”): ridge on posterior head region; present in some groups, oblique and short or more or less parallel to postocciptal rigde (Orthoptera). No true segmental border.\""} def: "The ridge that runs along the posterior region of the head capsule." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} synonym: "occipital suture" EXACT [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000158 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular ridge is_a: BSPO:0000077 ! proximal region [Term] id: AISM:0004049 name: postclypeus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Postclypeus: sclerotized and pigmented proximal part of clypeus.\""} def: "The region of cuticle comprising the posterior region of the clypeus." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle [Term] id: AISM:0004050 name: anteclypeus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Anteclypeus: transparent distal part of clypeus.\""} def: "The region of the cuticle comprising the anterior region of the clypeus." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle [Term] id: AISM:0004051 name: clypeolabrum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Clypeolabrum: area comprising the fused clypeus and labrum.\""} def: "The region of the cuticle that is composed of the clypeus and the labrum." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: BFO:0000051 AISM:0000042 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part labrum relationship: BFO:0000051 AISM:0004019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part clypeus [Term] id: AISM:0004052 name: insect compound eye {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Compound eye: paired main light sense organs; almost always composed of numerous ommatidia.\"", IAO:0000232="Modified 2023-01-09: specifying insect compound eye.\njgiron https://orcid.org/0000-0002-0851-6883"} def: "The sense organ of the insect head that is covered by the eye cuticle." [] {creation_date="2021-04-03", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000018 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! compound eye relationship: BFO:0000050 AISM:0000107 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect head relationship: BFO:0000051 AISM:0000088 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part eye cuticle [Term] id: AISM:0004053 name: insect ocellus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Ocellus: relatively simple median eye with single cornea lens and always lacking a crystalline cone: three are probably present in the groundplan of Insecta, but reductions occur in many groups.\"", IAO:0000232="Modified 2023-01-09: specifying insect ocellus.\njgiron https://orcid.org/0000-0002-0851-6883"} def: "The sense organ of the insect head that is covered by eye cuticle." [] {creation_date="2021-04-03", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000020 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! sense organ relationship: BFO:0000050 AISM:0000107 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect head relationship: BFO:0000051 AISM:0000088 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part eye cuticle [Term] id: AISM:0004054 name: laminatentoria {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"In some groups an accessory bridge is formed by medially fused internally directed processes, the laminatentoria. This feature is sometimes erroneously referred to as “perforated corpotentorium”.\""} def: "Are apophyses of the tentorium originating at each anterior tentorial arm." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000138 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular apophysis relationship: BFO:0000050 AISM:0000191 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of tentorium relationship: RO:0002150 AISM:0004038 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with anterior tentorial arm [Term] id: AISM:0004055 name: preabdomen {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Preabdomen (=pregenital segments): anterior abdominal segments (I–VII).\""} def: "The region of cuticle of the insect abdomen that is posteriorly connected to the postabdomen." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-05"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: BFO:0000050 AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect abdomen relationship: posteriorly_connected_to AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postabdomen [Term] id: AISM:0004056 name: postabdomen {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Postabdomen: posterior segments (VIII–XI) bearing genital appendages.\""} def: "The region of cuticle of the insect abdomen that is anteriorly connected to the preabdomen." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-05"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: anteriorly_connected_to AISM:0004055 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! preabdomen relationship: BFO:0000050 AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect abdomen [Term] id: AISM:0004057 name: abdominal tergite {AISM:0000171="Lawrence J, Ślipiński A (2013) 1 Australian beetles volume 1: morphology, classification and keys. CSIRO Publishing, 520 pp. \n\nhttps://www.publish.csiro.au/book/6466/\n\n\"major plate of the abdominal tergum\""} def: "The sclerite of the insect abdomen that is dorsal and medial." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} synonym: "abdominal tergum" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Tergum: plate-like dorsal sclerite of abdominal segment.\""} is_a: AISM:0000003 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite relationship: BFO:0000050 AISM:0000109 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! part of insect abdomen relationship: BFO:0000050 BSPO:0000079 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! part of dorsal region relationship: BFO:0000050 BSPO:0000083 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! part of medial region [Term] id: AISM:0004058 name: abdominal sternite def: "The sclerite of the insect abdomen that is ventral and medial." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} synonym: "abdominal sternum" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Sternum: plate-like ventral sclerite of abdominal segment.\""} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: BFO:0000050 AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect abdomen relationship: BFO:0000050 BSPO:0000083 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of medial region relationship: BFO:0000050 BSPO:0000084 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of ventral region [Term] id: AISM:0004059 name: pleural membrane {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Pleural membrane: lateral unsclerotized part of abdominal segments, connecting tergum and sternum; usually bearing spiracles I–VIII.\""} def: "The conjunctiva of the insect abdomen that surrounds the spiracles." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: AISM:0000078 AISM:0000135 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles insect spiracle relationship: BFO:0000050 AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect abdomen [Term] id: AISM:0004060 name: epiproct {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Epiproct: unpaired dorsal element (tergum) of segment XI.\""} def: "The sclerite of the postabdomen that is attached to the posterior margin of the abdominal tergite X by the abdominal tergite X-epiproct conjunctiva." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-05"} synonym: "proctiger" EXACT [] {AISM:0000171="Lawrence J, Ślipiński A (2013) 1 Australian beetles volume 1: morphology, classification and keys. CSIRO Publishing, 520 pp. \n\nhttps://www.publish.csiro.au/book/6466/\n\n[not defined]"} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: BFO:0000050 AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of postabdomen relationship: BSPO:0000098 AISM:0004197 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! dorsal to insect anus relationship: RO:0002150 AISM:0004120 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! continuous with abdominal tergite X-epiproct conjunctiva relationship: RO:0002150 AISM:0004197 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! continuous with insect anus [Term] id: AISM:0004061 name: paraproct {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Paraproct: paired lateral element of segment XI.\""} def: "The paired sclerite of the insect abdomen that is attached to the lateral margin of the abdominal tergite X by the abdominal tergite X-paraproct conjunctiva." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-05"} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: BFO:0000050 AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of postabdomen relationship: RO:0002150 AISM:0004167 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal tergite X-paraproct conjunctiva relationship: RO:0002220 AISM:0004197 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! adjacent to insect anus [Term] id: AISM:0004062 name: aedeagus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Aedeagus (penis is often used as a synonym): male copulatory organ.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticular evagination of the postabdomen that is distal and attached to the cuticle of parameres by the paramero-aedeagal conjunctiva and is connected to the endophallus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-05"} synonym: "insect penis" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Penis: main element of the male copulatory apparatus.\""} is_a: AISM:0000027 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular evagination relationship: BFO:0000050 AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of postabdomen relationship: BSPO:0000097 AISM:0004064 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! distal to paramere relationship: RO:0002150 AISM:0004063 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with endophallus relationship: RO:0002150 AISM:0004200 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with paramero-aedeagal conjunctiva relationship: RO:0002220 AISM:0004064 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to paramere property_value: IAO:0000589 "cuticle of aedeagus" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004063 name: endophallus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Endophallus: membranous extrusible internal part of aedeagus.\""} def: "The cuticular invagination of the postabdomen that is attached distally to the gonopore and basally to the aedeagus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-05"} is_a: AISM:0000006 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular invagination relationship: BFO:0000050 AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of postabdomen relationship: BSPO:0000097 AISM:0004075 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! distal to gonopore relationship: BSPO:0000100 AISM:0004062 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! proximal to aedeagus relationship: RO:0002220 AISM:0004062 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to aedeagus relationship: RO:0002220 AISM:0004075 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to gonopore [Term] id: AISM:0004064 name: paramere {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Parameres: paired lateral parts of aedeagus.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the paired cuticular evagination of the postabdomen that is attached to the cuticle of phallobase by the phallobasal-parameral conjunctiva and to the cuticle of aedeagus by the paramero-aedeagal conjunctiva." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-05"} is_a: AISM:0000027 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular evagination relationship: BFO:0000050 AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of postabdomen relationship: BSPO:0000097 AISM:0004065 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! distal to phallobase relationship: RO:0000053 PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has characteristic bilaterally paired relationship: RO:0002150 AISM:0004200 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with paramero-aedeagal conjunctiva relationship: RO:0002150 AISM:0004201 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with phallobasal-parameral conjunctiva relationship: RO:0002220 AISM:0004062 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to aedeagus property_value: IAO:0000589 "cuticle of paramere" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004065 name: phallobase {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Phallobase (=basal piece): part of segment IX bearing copulatory organ.\""} def: "The region of cuticle of the postabdomen that is attached to the abdominal sternite IX by the abdominal sternite IX-phallobase conjunctiva and to the paramere by the phallobasal-parameral conjunctiva." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-05"} synonym: "basal piece" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Phallobase (=basal piece): part of segment IX bearing copulatory organ.\""} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: BFO:0000050 AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of postabdomen relationship: RO:0002150 AISM:0004124 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal sternite IX-phallobase conjunctiva relationship: RO:0002150 AISM:0004201 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with phallobasal-parameral conjunctiva relationship: RO:0002220 AISM:0004064 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to paramere relationship: RO:0002220 AISM:0004119 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to abdominal sternite IX [Term] id: AISM:0004066 name: endophallite {AISM:0000171="Génier F (2019) Endophallites: a proposed neologism for naming the sclerotized elements of the insect endophallus (Arthropoda: Insecta). Annales de la Société entomologique de France (N.S.) 55: 482–484. \n\nhttps://doi.org/10.1080/00379271.2019.1685907 \n\n\"endophallite(s) refer to the sclerotized structures of the endophallus whether the structure be circular, flat, folded or spiniform.\""} def: "The region of cuticle of the endophallus that is thicker." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: BFO:0000050 AISM:0004063 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of endophallus relationship: RO:0000053 PATO:0000591 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has characteristic increased thickness [Term] id: AISM:0004067 name: bursa copulatrix {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Bursa copulatrix: evagination of the vagina, receives the copulatory organ.\""} def: "The region of the cuticle in the postabdomen that is attached to the genital chamber." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: BFO:0000050 AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of postabdomen relationship: RO:0002150 AISM:0004069 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with genital chamber [Term] id: AISM:0004068 name: gonocoxa VIII {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Coxopodite (=valvifer, gonocoxa, gonocoxite): short basal piece of ovipositor elements of female genital segments VIII and IX.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The paired sclerite of the postabdomen that is attached to the abdominal sternite VII by the abdominal sternite VII-gonocoxa conjunctiva and is articulated with abdominal tergite IX. It is attached at the base of gonostylus VIII and adjacent to the gonopore." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-05"} synonym: "first coxopodite" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Coxopodite (=valvifer, gonocoxa, gonocoxite): short basal piece of ovipositor elements of female genital segments VIII and IX.\""} synonym: "first gonocoxite" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Coxopodite (=valvifer, gonocoxa, gonocoxite): short basal piece of ovipositor elements of female genital segments VIII and IX.\""} synonym: "first valvifer" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Coxopodite (=valvifer, gonocoxa, gonocoxite): short basal piece of ovipositor elements of female genital segments VIII and IX.\""} is_a: AISM:0004301 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! gonocoxite relationship: RO:0002150 AISM:0004084 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal sternite VIII-gonocoxa VIII conjunctiva relationship: RO:0002220 AISM:0004075 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! adjacent to gonopore property_value: IAO:0000589 "cuticle of gonocoxa VIII" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004069 name: genital chamber {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Genital chamber: cavity formed by an inflection of the body wall, receiving the common oviduct.\""} def: "The region of cuticle that is connected to the oviduct, the bursa copulatrix and the gonocoxa VIII, and is adjacent to the gonopore." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-05"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: RO:0002150 AISM:0004067 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with bursa copulatrix relationship: RO:0002150 AISM:0004068 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with gonocoxa VIII relationship: RO:0002150 AISM:0004083 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with insect oviduct relationship: RO:0002220 AISM:0004075 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to gonopore [Term] id: AISM:0004070 name: gonapophysis {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Gonapophysis (=valves or valvulae 1–3): distal piece of ovipositor elements of female genital segments VIII and IX, inserted on coxopodites, usually elongated.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the appendage of the abdominal sternite VIII that is part of the ovipositor." [] {term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000029 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect appendage relationship: BFO:0000050 AISM:0004077 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of ovipositor relationship: BFO:0000050 AISM:0004110 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of abdominal sternite VIII property_value: IAO:0000589 "cuticle of gonapophysis" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004071 name: sensillum placodeum {IAO:0000232="Modified 2023-01-11: moved under cuticular sensilla; added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Sensillum placodeum: flat sensillum with strongly modified plate-like seta.\""} def: "The seta that is flattened." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0004304 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular sensilla relationship: BFO:0000051 AISM:0000039 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! has part cuticular seta relationship: RO:0000053 PATO:0000407 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has characteristic flat [Term] id: AISM:0004072 name: trichobothrium {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Trichobothrium: very long and fine sensillum, vibroreceptor.\""} def: "The seta that is elongated." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000039 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular seta relationship: RO:0000053 PATO:0001154 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has characteristic elongated [Term] id: AISM:0004073 name: paraphyses {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Paraphyses (=titillators): paired appendages of aedeagus.\""} def: "The proximal apodemes of the aedeagus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} synonym: "titillators" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Paraphyses (=titillators): paired appendages of aedeagus.\""} is_a: AISM:0000188 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! apodeme relationship: BSPO:0000100 AISM:0004062 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! proximal to aedeagus [Term] id: AISM:0004074 name: ductus ejaculatorius {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Ductus ejaculatorius: unpaired ectodermal duct connecting vasa deferentia (i.e. vesiculae seminales) and aedeagus.\""} def: "The region of the cuticle thar is proximally attached to the gonopore." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: BSPO:0000100 AISM:0004075 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! proximal to gonopore relationship: RO:0002220 AISM:0004075 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to gonopore [Term] id: AISM:0004075 name: gonopore {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Gonopore: external opening of the common oviduct.\"", creation_date="2021-03-05"} def: "The orifice in the postabdomen that marks the opening of the reproductive system." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: UBERON:0000161 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! orifice relationship: AISM:0000079 AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by postabdomen [Term] id: AISM:0004076 name: gonostylus VIII {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Gonostyli: appendages of gonocoxae (usually only on coxopodite IX)\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The region of the cuticle of the postabdomen that is paired and connected to the anterior region of the gonocoxa VIII." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-05"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: BFO:0000050 AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of postabdomen relationship: RO:0000053 PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has characteristic bilaterally paired property_value: IAO:0000589 "cuticle of gonostylus VIII" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004077 name: ovipositor {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Ovipositor: paired postabdominal apparatus (segments VIII and IX) primarily used for depositing eggs.\""} def: "The region of cuticle of the postabdomen that is distal to the genital chamber." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: BFO:0000050 AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of postabdomen relationship: BSPO:0000097 AISM:0004069 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! distal to genital chamber [Term] id: AISM:0004078 name: spermatheca {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Spermatheca (=receptaculum seminis): unpaired or paired evagination of female genital tract; storage of sperm; connected by spermathecal duct (=ductus receptaculi) with vagina or bursa copulatrix.\""} def: "The region of the cuticle that is part of the oviduct and connected to the bursa copulatrix." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: BFO:0000050 AISM:0004083 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect oviduct relationship: RO:0002150 AISM:0004067 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with bursa copulatrix [Term] id: AISM:0004079 name: spermathecal gland {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Spermathecal gland: provides nourishment for spermatozoa stored in spermatheca.\""} def: "The region of the cuticle that is part of the oviduct and attached to the spermatheca." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: BFO:0000050 AISM:0004083 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect oviduct relationship: RO:0002150 AISM:0004078 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with spermatheca [Term] id: AISM:0004080 name: precoxal sulcus def: "The sulcus that coincides with the precoxal ridge." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} synonym: "precoxal suture" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Precoxal suture: suture separating katepisternum and preepisternum.\""} is_a: AISM:0000162 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular sulcus relationship: RO:0002008 AISM:0004162 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! coincident with precoxal ridge [Term] id: AISM:0004081 name: pleural wing process {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Fulcrum (=pleural wing process): anterodorsal apex of the pleural ridge.\""} def: "The cuticular protrusion of the pleuron that is connected lateraly to the notum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} synonym: "fulcrum" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Fulcrum (=pleural wing process): anterodorsal apex of the pleural ridge.\""} is_a: AISM:0000008 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular protrusion relationship: AISM:0000011 AISM:0004128 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! lateral_to notum relationship: BFO:0000050 AISM:0004129 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of pleuron [Term] id: AISM:0004082 name: metanoto-abdominal tergite I conjunctiva def: "The conjunctiva between the insect thorax and the insect abdomen that connects the posterior margin of the metanotum to the anterior margin of the abdominal tergite I." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: RO:0002150 AISM:0000021 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal tergite I relationship: RO:0002150 AISM:0000169 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with metanotum [Term] id: AISM:0004083 name: insect oviduct {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Oviduct: female genital duct; originating as paired structures from ovarioles, uniting as common (median) oviduct.\""} def: "The region of cuticle that is continuous with the genital chamber." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle is_a: UBERON:0000993 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! oviduct relationship: RO:0002150 AISM:0004069 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with genital chamber [Term] id: AISM:0004084 name: abdominal sternite VIII-gonocoxa VIII conjunctiva def: "The conjunctiva of the insect abdomen that joins the abdominal sternite VIII and the gonocoxa VIII." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-01-09: correct sternite VII to VIII.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: BFO:0000050 AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect abdomen relationship: RO:0002150 AISM:0004068 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with gonocoxa VIII relationship: RO:0002150 AISM:0004110 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal sternite VIII [Term] id: AISM:0004085 name: abdominal tergite II def: "Is the abdominal tergite of the preabdomen that is attached to the posterior margin of the abdominal tergite I by the abdominal tergite I-abdominal tergite II conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004057 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite relationship: anteriorly_connected_to AISM:0004086 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite I-abdominal tergite II conjunctiva relationship: BFO:0000050 AISM:0004055 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of preabdomen [Term] id: AISM:0004086 name: abdominal tergite I-abdominal tergite II conjunctiva def: "The conjunctiva of the insect abdomen that connects the abdominal tergite I and the abdominal tergite II." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: BFO:0000050 AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect abdomen relationship: RO:0002150 AISM:0000021 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal tergite I relationship: RO:0002150 AISM:0004085 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal tergite II [Term] id: AISM:0004087 name: abdominal tergite III def: "Is the abdominal tergite of the preabdomen that is attached to the posterior margin of the abdominal tergite II by the abdominal tergite II-abdominal tergite III conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004057 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite relationship: anteriorly_connected_to AISM:0004088 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite II-abdominal tergite III conjunctiva relationship: BFO:0000050 AISM:0004055 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of preabdomen [Term] id: AISM:0004088 name: abdominal tergite II-abdominal tergite III conjunctiva def: "The conjunctiva of the insect abdomen that connects the abdominal tergite II and the abdominal tergite III." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: BFO:0000050 AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect abdomen relationship: RO:0002150 AISM:0004085 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal tergite II relationship: RO:0002150 AISM:0004087 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal tergite III [Term] id: AISM:0004089 name: abdominal tergite III-abdominal tergite IV conjunctiva def: "The conjunctiva of the insect abdomen that connects the abdominal tergite III and the abdominal tergite IV." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: BFO:0000050 AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect abdomen relationship: RO:0002150 AISM:0004087 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal tergite III relationship: RO:0002150 AISM:0004090 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal tergite IV [Term] id: AISM:0004090 name: abdominal tergite IV def: "Is the abdominal tergite of the preabdomen that is attached to the posterior margin of the abdominal tergite III by the abdominal tergite III-abdominal tergite IV conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004057 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite relationship: anteriorly_connected_to AISM:0004089 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite III-abdominal tergite IV conjunctiva relationship: BFO:0000050 AISM:0004055 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of preabdomen [Term] id: AISM:0004091 name: abdominal tergite V def: "Is the abdominal tergite of the preabdomen that is attached to the posterior margin of the abdominal tergite IV by the abdominal tergite IV-abdominal tergite V conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004057 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite relationship: anteriorly_connected_to AISM:0004092 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite IV-abdominal tergite V conjunctiva relationship: BFO:0000050 AISM:0004055 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of preabdomen [Term] id: AISM:0004092 name: abdominal tergite IV-abdominal tergite V conjunctiva def: "The conjunctiva of the insect abdomen that connects the abdominal tergite IV and the abdominal tergite V." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: BFO:0000050 AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect abdomen relationship: RO:0002150 AISM:0004090 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal tergite IV relationship: RO:0002150 AISM:0004091 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal tergite V [Term] id: AISM:0004093 name: abdominal tergite VI def: "Is the abdominal tergite of the preabdomen that is attached to the posterior margin of the abdominal tergite V by the abdominal tergite V-abdominal tergite VI conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004057 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite relationship: anteriorly_connected_to AISM:0004094 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite V-abdominal tergite VI conjunctiva relationship: BFO:0000050 AISM:0004055 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of preabdomen [Term] id: AISM:0004094 name: abdominal tergite V-abdominal tergite VI conjunctiva def: "The conjunctiva of the insect abdomen that connects the abdominal tergite V and the abdominal tergite VI." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: BFO:0000050 AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect abdomen relationship: RO:0002150 AISM:0004091 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal tergite V relationship: RO:0002150 AISM:0004093 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal tergite VI [Term] id: AISM:0004095 name: abdominal tergite VII def: "Is the abdominal tergite of the preabdomen that is attached to the posterior margin of the abdominal tergite VI by the abdominal tergite VI-abdominal tergite VII conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004057 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite relationship: anteriorly_connected_to AISM:0004096 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite VI-abdominal tergite VII conjunctiva relationship: BFO:0000050 AISM:0004055 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of preabdomen [Term] id: AISM:0004096 name: abdominal tergite VI-abdominal tergite VII conjunctiva def: "The conjunctiva of the insect abdomen that connects the abdominal tergite VI and the abdominal tergite VII." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: BFO:0000050 AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect abdomen relationship: RO:0002150 AISM:0004093 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal tergite VI relationship: RO:0002150 AISM:0004095 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal tergite VII [Term] id: AISM:0004097 name: abdominal tergite VIII def: "Is the abdominal tergite of the postabdomen that is attached to the posterior margin of the abdominal tergite VII by the abdominal tergite VII-abdominal tergite VIII conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004057 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite relationship: anteriorly_connected_to AISM:0004098 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite VII-abdominal tergite VIII conjunctiva relationship: BFO:0000050 AISM:0000523 ! part of dorsal postabdomen [Term] id: AISM:0004098 name: abdominal tergite VII-abdominal tergite VIII conjunctiva def: "The conjunctiva of the insect abdomen that connects the abdominal tergite VII and the abdominal tergite VIII." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: BFO:0000050 AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect abdomen relationship: RO:0002150 AISM:0004095 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal tergite VII relationship: RO:0002150 AISM:0004097 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal tergite VIII [Term] id: AISM:0004099 name: laterotergite {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Laterotergite: separate lateral portion of abdominal tergum (only few groups).\""} def: "The sclerite of the insect thorax or the insect abdomen that is on the lateral region of the notum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} synonym: "paranota" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Paranota (=laterotergites): dorsolateral tergal duplicatures.\""} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: BFO:0000050 AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect abdomen [Term] id: AISM:0004100 name: abdominal sternite I def: "The abdominal sternite of the preabdomen that is attached to the posterior margin of the metasternum by the metasterno-abdominal sternite I conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004058 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite relationship: anteriorly_connected_to AISM:0004102 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metasterno-abdominal sternite I conjunctiva relationship: BFO:0000050 AISM:0004055 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of preabdomen [Term] id: AISM:0004101 name: metapleuro-metasternal conjunctiva def: "The conjunctiva of the metathorax that joins the metapleura and the metasternum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: BFO:0000050 AISM:0004127 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of metathorax relationship: RO:0002150 AISM:0000119 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with metapleuron relationship: RO:0002150 AISM:0004232 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with metasternum [Term] id: AISM:0004102 name: metasterno-abdominal sternite I conjunctiva def: "The conjunctiva between the insect thorax and the insect abdomen that connects the posterior margin of the metasterum to the anterior margin of the abdominal sternite I." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: RO:0002150 AISM:0004100 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal sternite I relationship: RO:0002150 AISM:0004101 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with metapleuro-metasternal conjunctiva [Term] id: AISM:0004103 name: abdominal sternite I-abdominal sternite II conjunctiva def: "The conjunctiva of the insect abdomen that connects the abdominal sternite I and the abdominal sternite II." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: BFO:0000050 AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect abdomen relationship: RO:0002150 AISM:0004100 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal sternite I relationship: RO:0002150 AISM:0004104 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal sternite II [Term] id: AISM:0004104 name: abdominal sternite II def: "The abdominal tergite of the preabdomen that is attached to the posterior margin of the abdominal sternite I by the abdominal sternite I-abdominal sternite II conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004058 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite relationship: anteriorly_connected_to AISM:0004103 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite I-abdominal sternite II conjunctiva relationship: BFO:0000050 AISM:0004055 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of preabdomen [Term] id: AISM:0004105 name: abdominal sternite III def: "The abdominal sternite of the preabdomen that is attached to the posterior margin of the abdominal sternite II by the abdominal sternite II-abdominal sternite III conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004058 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite relationship: anteriorly_connected_to AISM:0004111 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite II-abdominal sternite III conjunctiva relationship: BFO:0000050 AISM:0004055 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of preabdomen [Term] id: AISM:0004106 name: abdominal sternite IV def: "The abdominal sternite of the preabdomen that is attached to the posterior margin of the abdominal sternite III by the abdominal sternite III-abdominal sternite IV conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004058 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite relationship: anteriorly_connected_to AISM:0004112 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite III-abdominal sternite IV conjunctiva relationship: BFO:0000050 AISM:0004055 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of preabdomen [Term] id: AISM:0004107 name: abdominal sternite V def: "The abdominal sternite of the preabdomen that is attached to the posterior margin of the abdominal sternite IV by the abdominal sternite IV-abdominal sternite V conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004058 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite relationship: anteriorly_connected_to AISM:0004113 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite IV-abdominal sternite V conjunctiva relationship: BFO:0000050 AISM:0004055 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of preabdomen [Term] id: AISM:0004108 name: abdominal sternite VI def: "The abdominal sternite of the preabdomen that is attached to the posterior margin of the abdominal sternite V by the abdominal sternite V-abdominal sternite VI conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004058 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite relationship: anteriorly_connected_to AISM:0004114 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite V-abdominal sternite VI conjunctiva relationship: BFO:0000050 AISM:0004055 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of preabdomen [Term] id: AISM:0004109 name: abdominal sternite VII def: "The abdominal sternite of the preabdomen that is attached to the posterior margin of the abdominal sternite VI by the abdominal sternite VI-abdominal sternite VII conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004058 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite relationship: anteriorly_connected_to AISM:0004115 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite VI-abdominal sternite VII conjunctiva relationship: BFO:0000050 AISM:0004055 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of preabdomen [Term] id: AISM:0004110 name: abdominal sternite VIII def: "The abdominal sternite of the postabdomen that is attached to the posterior margin of the abdominal sternite VII by the abdominal sternite VII-abdominal sternite VIII conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004058 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite relationship: BFO:0000050 AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of postabdomen relationship: posteriorly_connected_to AISM:0004123 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite VIII-abdominal sternite IX conjunctiva [Term] id: AISM:0004111 name: abdominal sternite II-abdominal sternite III conjunctiva def: "The conjunctiva of the insect abdomen that connects the abdominal sternite II and the abdominal sternite III." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: BFO:0000050 AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect abdomen relationship: RO:0002150 AISM:0004104 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal sternite II relationship: RO:0002150 AISM:0004105 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal sternite III [Term] id: AISM:0004112 name: abdominal sternite III-abdominal sternite IV conjunctiva def: "The conjunctiva of the insect abdomen that connects the abdominal sternite III and the abdominal sternite IV." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: BFO:0000050 AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect abdomen relationship: RO:0002150 AISM:0004105 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal sternite III relationship: RO:0002150 AISM:0004106 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal sternite IV [Term] id: AISM:0004113 name: abdominal sternite IV-abdominal sternite V conjunctiva def: "The conjunctiva of the insect abdomen that connects the abdominal sternite IV and the abdominal sternite V." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: BFO:0000050 AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect abdomen relationship: RO:0002150 AISM:0004106 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal sternite IV relationship: RO:0002150 AISM:0004107 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal sternite V [Term] id: AISM:0004114 name: abdominal sternite V-abdominal sternite VI conjunctiva def: "The conjunctiva of the insect abdomen that connects the abdominal sternite V and the abdominal sternite VI." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: BFO:0000050 AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect abdomen relationship: RO:0002150 AISM:0004107 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal sternite V relationship: RO:0002150 AISM:0004108 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal sternite VI [Term] id: AISM:0004115 name: abdominal sternite VI-abdominal sternite VII conjunctiva def: "The conjunctiva of the insect abdomen that connects the abdominal sternite VI and the abdominal sternite VII." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: BFO:0000050 AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect abdomen relationship: RO:0002150 AISM:0004108 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal sternite VI relationship: RO:0002150 AISM:0004109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal sternite VII [Term] id: AISM:0004116 name: abdominal sternite VII-abdominal sternite VIII conjunctiva def: "The conjunctiva of the insect abdomen that connects the abdominal sternite VII and the abdominal sternite VIII." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: BFO:0000050 AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect abdomen relationship: RO:0002150 AISM:0004109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal sternite VII relationship: RO:0002150 AISM:0004110 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal sternite VIII [Term] id: AISM:0004117 name: abdominal tergite IX def: "Is the abdominal tergite of the postabdomen that is attached to the posterior margin of the abdominal tergite VIII by the abdominal tergite VIII-abdominal tergite IX conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004057 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite relationship: anteriorly_connected_to AISM:0004121 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite VIII-abdominal tergite IX conjunctiva relationship: BFO:0000050 AISM:0000523 ! part of dorsal postabdomen [Term] id: AISM:0004118 name: abdominal tergite X def: "Is the abdominal tergite of the postabdomen that is attached to the posterior margin of the abdominal tergite IX by the abdominal tergite IX-abdominal tergite X conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004057 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite relationship: anteriorly_connected_to AISM:0004122 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite IX-abdominal tergite X conjunctiva relationship: BFO:0000050 AISM:0000523 ! part of dorsal postabdomen [Term] id: AISM:0004119 name: abdominal sternite IX def: "The abdominal sternite of the postabdomen that is attached to the posterior margin of the abdominal sternite VIII by the abdominal sternite VIII-abdominal sternite IX conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004058 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite relationship: anteriorly_connected_to AISM:0004116 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite VII-abdominal sternite VIII conjunctiva relationship: BFO:0000050 AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of postabdomen [Term] id: AISM:0004120 name: abdominal tergite X-epiproct conjunctiva def: "The conjunctiva of the postabdomen that joins the abdominal tergite X and the epiproct." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: BFO:0000050 AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of postabdomen relationship: RO:0002150 AISM:0004060 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with epiproct relationship: RO:0002150 AISM:0004118 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal tergite X [Term] id: AISM:0004121 name: abdominal tergite VIII-abdominal tergite IX conjunctiva def: "The conjunctiva of the insect abdomen that connects the abdominal tergite VIII and the abdominal tergite IX." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: BFO:0000050 AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect abdomen relationship: RO:0002150 AISM:0004097 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal tergite VIII relationship: RO:0002150 AISM:0004117 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal tergite IX [Term] id: AISM:0004122 name: abdominal tergite IX-abdominal tergite X conjunctiva def: "The conjunctiva of the insect abdomen that connects the abdominal tergite IX and the abdominal tergite X." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: BFO:0000050 AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect abdomen relationship: RO:0002150 AISM:0004117 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal tergite IX relationship: RO:0002150 AISM:0004118 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal tergite X [Term] id: AISM:0004123 name: abdominal sternite VIII-abdominal sternite IX conjunctiva def: "The conjunctiva of the insect abdomen that connects the abdominal sternite VIII and the abdominal sternite IX." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: BFO:0000050 AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect abdomen relationship: RO:0002150 AISM:0004110 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal sternite VIII relationship: RO:0002150 AISM:0004119 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal sternite IX [Term] id: AISM:0004124 name: abdominal sternite IX-phallobase conjunctiva def: "The conjunctiva of the insect abdomen that connects the abdominal sternite IX and the abdominal sternite X." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: BFO:0000050 AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect abdomen relationship: RO:0002150 AISM:0004065 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with phallobase relationship: RO:0002150 AISM:0004119 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal sternite IX [Term] id: AISM:0004125 name: prothorax {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Prothorax: 1st thoracic segment, always completely wingless in extant hexapods.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The region of the cuticle of the insect thorax that is anteriorly connected to the head by the neck membrane, posteriorly connected to the mesothorax by the prothorax-mesothorax conjunctiva, and contains the pronotum, the propeluron, the prosternum and one pair of legs." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: anteriorly_connected_to AISM:0000098 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! neck membrane relationship: BFO:0000050 AISM:0000108 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect thorax relationship: BFO:0000051 AISM:0000034 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part fore leg relationship: BFO:0000051 AISM:0000059 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part pronotum relationship: BFO:0000051 AISM:0000060 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part labial palpomere relationship: BFO:0000051 AISM:0000061 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part prosternum relationship: posteriorly_connected_to AISM:0000046 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prothoracic-mesothoracic conjunctiva property_value: IAO:0000589 "cuticle of prothorax" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004126 name: mesothorax {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Mesothorax: 2nd thoracic segment, anterior segment of pterothorax; bearing forewings (groundplan of Pterygota).\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The region of the cuticle of the pterothorax that bears mid legs and fore wings." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: BFO:0000050 AISM:0004166 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of pterothorax relationship: BFO:0000051 AISM:0000035 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part mid leg relationship: BFO:0000051 AISM:0000037 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part fore wing property_value: IAO:0000589 "cuticle of mesothorax" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004127 name: metathorax {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Metathorax: 3rd thoracic segment, posterior segment of pterothorax; bearing hindwings (groundplan of Pterygota).\"", term:modified="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The region of the cuticle of the pterothorax that bears the hind legs and the hind wings." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: BFO:0000050 AISM:0004166 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of pterothorax relationship: BFO:0000051 AISM:0000036 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part hind leg relationship: BFO:0000051 AISM:0000038 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part hind wing property_value: IAO:0000589 "cuticle of metathorax" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004128 name: notum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Notum: larger anterior part of tergum, composed of presutum, scutum and scutellum.\""} def: "The dorsal region of the cuticle of the insect thorax that is attached to the dorsal margin of the pleuron." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} synonym: "tergum" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Tergum: dorsal wall of a thoracic (or abdominal) segment.\""} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle [Term] id: AISM:0004129 name: pleuron {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Pleuron: lateral wall of thoracic segments, almost always divided by pleural ridge into anterior episternum and posterior epimeron.\""} def: "The region of cuticle on the lateral region of the insect thorax that is attached to the notum and the sternum and is attached to the coxae by skeletal muscle tissue and the basal coxal conjunctiva." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle is_a: UBERON:0000061 ! anatomical structure relationship: RO:0002150 AISM:0000173 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! continuous with basal coxal conjunctiva relationship: RO:0002220 AISM:0004128 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to notum relationship: RO:0002220 AISM:0004130 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to sternum [Term] id: AISM:0004130 name: sternum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Sternum: ventral wall of thoracic (or abdominal) segment, usually divided into presternum, basisternum, furcasternum and spinasternum in unspecialized hexapods; largely or completely invaginated in Holometabola (cryptosterny).\""} def: "The ventral region of the cuticle of the insect thorax that is attached to the ventral margin of the pleuron." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle [Term] id: AISM:0004131 name: pleurite {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Pleurite: sclerotized element of pleuron.\""} def: "The sclerite that is part of the pleuron." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: BFO:0000050 AISM:0004129 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of pleuron [Term] id: AISM:0004132 name: pleural ridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Pleural ridge: internal ridge, corresponding to externally visible pleural “suture”; separates episternum and epimeron; anterodorsally forming the pleural wing process and posteroventrally the pleuro-coxal joint.\""} def: "The ridge between the epimeron and the episternum in either the mesothorax or the metathorax." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000158 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular ridge relationship: RO:0002150 AISM:0004133 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with episternum relationship: RO:0002150 AISM:0004134 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with epimeron [Term] id: AISM:0004133 name: episternum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Episternum: part of pleuron anterior to pleural ridge.\""} def: "The sclerite of the insect thorax that is part of the pleuron and anterior to the pleural ridge and attached to the anterior margin of the epimeron." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: BFO:0000050 AISM:0004129 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of pleuron relationship: BSPO:0000096 AISM:0004132 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anterior to pleural ridge relationship: RO:0000053 PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has characteristic bilaterally paired [Term] id: AISM:0004134 name: epimeron {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Epimeron: part of pleuron posterior to pleural ridge.\""} def: "The sclerite of the insect thorax that is part of the pleuron and posterior to the pleural ridge and attached to the posterior margin of the episternum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: BFO:0000050 AISM:0004129 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of pleuron relationship: BSPO:0000099 AISM:0004132 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! posterior to pleural ridge relationship: RO:0000053 PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has characteristic bilaterally paired [Term] id: AISM:0004135 name: trochantin {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Trochantin: small triangular or sickle-shaped ventral pleural sclerite; anteriorly articulating with coxa (trochantino-coxal joint).\""} def: "The sclerite that is located on the ventro-lateral region of the insect thorax and is attached to a coxa." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: AISM:0000079 AISM:0000173 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by basal coxal conjunctiva relationship: RO:0002220 AISM:0000077 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to coxa [Term] id: AISM:0004136 name: presternum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Presternum: anteriormost part of sternum.\""} def: "The part of the sternum that is attached to the anterior margin of the basisternum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0004130 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! sternum [Term] id: AISM:0004137 name: basisternum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Basisternum: main part of sternum, between presternum and furcasternum.\""} def: "The part of the sternum that is attached to the posterior margin of the presternum and to the anterior margin of the furcasternum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0004130 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! sternum [Term] id: AISM:0004138 name: furcasternum {x_1.1:contributor="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Furcasternum (=sternellum): sternal element posterior to basisternum, area of origin of furca.\""} def: "The part of the sternum that is attached to the posterior margin of the basisternum and to the anterior margin of the spinasternum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} synonym: "sternellum" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Furcasternum (=sternellum): sternal element posterior to basisternum, area of origin of furca.\""} is_a: AISM:0004130 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! sternum [Term] id: AISM:0004139 name: spinasternum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Spinasternum: small posterior sternal element, determining the posterior segmental border; area of origin of spina.\""} def: "The part of the sternum that is attached to the posterior margin of the furcasternum and to the anterior margin of the poststernite." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0004130 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! sternum [Term] id: AISM:0004140 name: poststernite {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Poststernite: posteriormost sternal element.\""} def: "The part of the sternum that is attached to the posterior margin of the spinasternum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0004130 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! sternum [Term] id: AISM:0004141 name: cervical sclerite {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Cervical sclerite: articulatory sclerite embedded in the cervical membrane.\""} def: "The sclerite that is surrounded by the neck membrane." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: AISM:0000079 AISM:0000098 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by neck membrane [Term] id: AISM:0004142 name: propleuron def: "The region of the cuticle on the lateral region of the prothorax that is attached to the pronotum and the prosternum, and is attached to the procoxa by the procoxal muscle and the basal procoxal conjunctiva." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004129 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pleuron relationship: RO:0002150 AISM:0000106 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with basal procoxal conjunctiva relationship: RO:0002150 AISM:0000145 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with procoxal muscle relationship: RO:0002220 AISM:0000059 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to pronotum relationship: RO:0002220 AISM:0000061 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to prosternum [Term] id: AISM:0004143 name: postnotum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Postnotum: smaller posterior part of tergum, forming internal intersegmental phragma; attachment area for dorsal indirect flight muscles.\""} def: "The sclerite of the notum that is attached to the posterior margin of the scutellum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: BFO:0000050 AISM:0004128 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of notum [Term] id: AISM:0004144 name: prescutum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Prescutum: anteriormost part of notum.\""} def: "The sclerite of the notum that is attached to the anterior margin of the scutum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: BFO:0000050 AISM:0004128 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of notum [Term] id: AISM:0004145 name: scutum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Scutum: large anterior part of notum.\""} def: "The sclerite of the notum that is attached to the posterior margin of the prescutum and to the anterior margin of the scutellum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: BFO:0000050 AISM:0004128 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of notum [Term] id: AISM:0004146 name: scutellum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Scutellum: smaller posterior part of notum.\""} def: "The sclerite of the notum that is attached to the posterior margin of the scutum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: BFO:0000050 AISM:0004128 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of notum [Term] id: AISM:0004147 name: alinotum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Alinotum: part of the notum connected with the wing base.\""} def: "The sclerite that is on the lateral region of the notum and is adjacent to the wing." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: RO:0002220 AISM:0000033 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to insect wing [Term] id: AISM:0004148 name: prealar sclerite {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Prealare (=prealar sclerite): small attachment area of short direct flight muscles.\""} def: "The sclerite of the pterothorax that is attached to some muscle." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} synonym: "prealare" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Prealare (=prealar sclerite): small attachment area of short direct flight muscles.\""} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: BFO:0000050 AISM:0004166 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of pterothorax relationship: RO:0002150 UBERON:0014895 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with somatic muscle, invertebrate [Term] id: AISM:0004149 name: prealar bridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Prealar bridge: prescutal process, bent downwards and linked with episternum.\""} def: "The region of cuticle of the dorso-lateral region of the pterothorax that is surrounded by the noto-pleural conjunctiva and articulated with the episternum." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: RO:0002150 AISM:0004222 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with noto-pleural conjunctiva relationship: RO:0002220 AISM:0004133 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to episternum [Term] id: AISM:0004150 name: postalar bridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Postalar bridge: lateral postnotal margin bent downwards and connected with the epimeron.\""} def: "The region of cuticle of the dorso-lateral region of the pterothorax that is surrounded by the noto-pleural conjunctiva and articulated with the epimeron." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: RO:0002150 AISM:0004222 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with noto-pleural conjunctiva relationship: RO:0002220 AISM:0004134 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to epimeron [Term] id: AISM:0004151 name: epipleurite {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Epipleurites: basalare and subalare.\""} def: "The sclerite of the insect thorax that is surrounded by the noto-pleural conjunctiva and is adjacent to the wing." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: AISM:0000079 AISM:0004080 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by precoxal sulcus relationship: BFO:0000050 AISM:0000108 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect thorax relationship: RO:0002220 AISM:0000033 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to insect wing [Term] id: AISM:0004152 name: basalare {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Basalare: sclerite associated with wing base, more or less distinctly separated from anepisternum; usually with internal muscle disc; attachment site of direct flight muscles.\""} def: "The epipleurite that is adjacent to the anepisternum, is attached to the pleuron via muscle, is surrounded by the noto-pleural conjunctiva, and is anterior to the first axillary sclerite." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0004151 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! epipleurite is_a: UBERON:0000061 ! anatomical structure relationship: AISM:0000079 AISM:0004222 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by noto-pleural conjunctiva relationship: BSPO:0000096 AISM:0000022 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! anterior to first axillary sclerite relationship: RO:0002220 AISM:0004154 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to anepisternum [Term] id: AISM:0004153 name: subalare {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Subalare: sclerite associated with wing base, usually embedded in membrane between tergum and pleuron; attachment site of direct flight muscles.\""} def: "The epipleurite that is adjacent to the notum, is attached to the coxa via muscle, is surrounded by the noto-pleural conjunctiva, and is posterior to the first axillary sclerite." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0004151 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! epipleurite is_a: UBERON:0000061 ! anatomical structure relationship: AISM:0000079 AISM:0004222 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by noto-pleural conjunctiva relationship: BSPO:0000099 AISM:0000022 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! posterior to first axillary sclerite relationship: RO:0002220 AISM:0004128 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to notum [Term] id: AISM:0004154 name: anepisternum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Anepisternum: dorsal part of episternum, ventrally delimited by anapleural suture.\""} def: "The dorsal region of the episternum that is dorsal to the anapleural sulcus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: BSPO:0000098 AISM:0004156 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! dorsal to anapleural sulcus relationship: RO:0000053 PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has characteristic bilaterally paired [Term] id: AISM:0004155 name: preepisternum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Preepisternum: anterior part of ventral episternal region; delimited from katepisternum by precoxal suture; largest part of ventrite in Holometabola.\""} def: "The region of cuticle on the antero-ventral region of the episternum that is anterior to the anapleural sulcus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: BSPO:0000096 AISM:0004156 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anterior to anapleural sulcus [Term] id: AISM:0004156 name: anapleural sulcus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Anapleural suture (=paracoxal suture): suture horizontally delimiting dorsal and ventral parts of episternum and (partially) epimeron; sometimes anteriorly widened and membranous (=anapleural cleft).\""} def: "The sulcus of the pleuron delimiting the dorsal region of the preepisternum and the ventral region of the anepisternum." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} synonym: "anapleural cleft" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Anapleural suture (=paracoxal suture): suture horizontally delimiting dorsal and ventral parts of episternum and (partially) epimeron; sometimes anteriorly widened and membranous (=anapleural cleft).\""} synonym: "paracoxal suture" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Anapleural suture (=paracoxal suture): suture horizontally delimiting dorsal and ventral parts of episternum and (partially) epimeron; sometimes anteriorly widened and membranous (=anapleural cleft).\""} is_a: AISM:0000162 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular sulcus relationship: BFO:0000050 AISM:0004129 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of pleuron [Term] id: AISM:0004157 name: ecdysial line def: "The anatomical line of weakness of the cuticle that allows molting and coincides with a suture." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} synonym: "molting line" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Molting lines (frontal and coronal sutures [=epicranial lines or sutures])\""} is_a: CARO:0000008 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anatomical line relationship: RO:0002008 AISM:0004028 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! coincident with cuticular suture [Term] id: AISM:0004158 name: katepisternum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Katepisternum: posterior part of ventral episternal region; separated from preepisternum by precoxal suture.\""} def: "The region of cuticle on the postero-ventral region of the episternum that is posterior to the anapleural sulcus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: BSPO:0000099 AISM:0004156 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! posterior to anapleural sulcus [Term] id: AISM:0004159 name: anepimeron {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Anepimeron: dorsal part of epimeron (present as separate element in some groups).\""} def: "The region of the cuticle on the dorsal region of the epimeron." [] {creation_date="2021-04-10", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: RO:0000053 PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has characteristic bilaterally paired [Term] id: AISM:0004160 name: katepimeron {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Katepimeron: ventral part of epimeron (present as separate element in some groups).\""} def: "The region of cuticle on the ventral region of the epimeron." [] {creation_date="2021-04-10", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle [Term] id: AISM:0004161 name: axillary sclerite {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Axillary sclerites (=axillaria, pteralia): small sclerites of wing base (usually 3); articulating with notal wing processes.\""} def: "The sclerite that is surrounded by the basal wing conjunctiva." [] {creation_date="2021-04-10", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} synonym: "pteralia" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Pteralia: small sclerites of wing base (axillary sclerites + plates).\""} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: AISM:0000079 AISM:0004203 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by basal wing conjunctiva relationship: BFO:0000050 AISM:0004258 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of axillary region of the insect wing [Term] id: AISM:0004162 name: precoxal ridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Precoxal ridge: mediolaterally directed ridge in front of coxa, corresponding with externally visible precoxal suture.\""} def: "The ridge that is anterior to a coxa, demarcated by the anapleural sulcus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0000158 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular ridge relationship: BSPO:0000096 AISM:0000077 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anterior to coxa relationship: RO:0002150 AISM:0004156 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with anapleural sulcus [Term] id: AISM:0004163 name: spina {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Spina: smaller posterior endoskeletal element of thoracic segments, unpaired, arising on spinasternum.\""} def: "The sclerite attached to the spinasternum." [] {creation_date="2021-04-10", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: RO:0002150 AISM:0004139 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with spinasternum [Term] id: AISM:0004165 name: cercus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Cerci: tactile appendages of segment XI, primarily multisegmented and tactile bearing setae.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The bilaterally paired region of the cuticle of the postabdomen located between the epiproct and the paraproct" [] {creation_date="2021-04-10", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle intersection_of: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! insect region of cuticle intersection_of: BFO:0000050 AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! part of postabdomen intersection_of: RO:0000053 PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! has characteristic bilaterally paired intersection_of: RO:0002220 AISM:0004060 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! adjacent to epiproct relationship: BFO:0000050 AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of postabdomen relationship: RO:0000053 PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has characteristic bilaterally paired relationship: RO:0002220 AISM:0004060 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to epiproct relationship: RO:0002220 AISM:0004061 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to paraproct property_value: IAO:0000589 "cuticle of cercus" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004166 name: pterothorax {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Pterothorax: 2nd and 3nd thoracic segments; bearing wings (groundplan of Pterygota), meso- and metathorax.\""} def: "The region of cuticle of the insect thorax that contains the mesothorax and the metathorax and bears the mid legs, the hind legs and the wings." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: BFO:0000050 AISM:0000108 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect thorax relationship: BFO:0000051 AISM:0004126 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part mesothorax relationship: BFO:0000051 AISM:0004127 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part metathorax [Term] id: AISM:0004167 name: abdominal tergite X-paraproct conjunctiva def: "The conjunctiva of the postabdomen that joins the abdominal tergite X and each paraproct." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: BFO:0000050 AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of postabdomen relationship: RO:0002150 AISM:0004061 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with paraproct relationship: RO:0002150 AISM:0004118 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with abdominal tergite X [Term] id: AISM:0004168 name: trochanter {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Trochanter: 2nd element of leg, usually small and triangular.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of a leg attached to the distal margin of the coxa by the coxal-trochanteral conjunctiva and to the proximal margin of the femur by the trochantero-femoral conjunctiva." [] {term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0000063 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! appendage segment relationship: AISM:0000078 AISM:0004174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles trochantero-femoral conjunctiva relationship: AISM:0000079 AISM:0004170 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by coxal-trochanteral conjunctiva relationship: BFO:0000050 AISM:0000031 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect leg relationship: RO:0000053 PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has characteristic bilaterally paired property_value: IAO:0000589 "cuticle of trochanter" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004169 name: tarsus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Tarsus: 5th part of leg; undivided in entognathous orders, composed of 3–5 tarsomeres in most groups of Insecta.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of the leg that is composed of tarsomeres connected to each other by intertarsomeral conjunctiva. The first tarsomere is connected to the distal margin of the tibia by the tibio-tarsal conjunctiva." [] {term:modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0000063 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! appendage segment relationship: AISM:0000079 AISM:0004182 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by tibio-tarsal conjunctiva relationship: BFO:0000050 AISM:0000031 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect leg relationship: BFO:0000051 AISM:0000074 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part tarsomere relationship: RO:0000053 PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has characteristic bilaterally paired property_value: IAO:0000589 "cuticle of tarsus" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004170 name: coxal-trochanteral conjunctiva def: "The conjunctiva of the leg joining the distal margin of a coxa and the proximal margin of a femur." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000102 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! ring conjunctiva relationship: AISM:0000078 AISM:0004168 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles trochanter relationship: BFO:0000050 AISM:0000031 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect leg [Term] id: AISM:0004171 name: protrochanter {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of a fore leg attached to the distal margin of the procoxa by the procoxal-protrochanteral conjunctiva and to the proximal margin of the profemur by the protrochantero-profemoral conjunctiva." [] {term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0004168 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! trochanter relationship: AISM:0000078 AISM:0004175 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles protrochantero-profemoral conjunctiva relationship: AISM:0000079 AISM:0000123 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by procoxal-protrochanteral conjunctiva relationship: BFO:0000050 AISM:0000034 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of fore leg property_value: IAO:0000589 "cuticle of protrochanter" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004172 name: mesotrochanter {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of a mid leg attached to the distal margin of the mesocoxa by the mesocoxal-mesotrochanteral conjunctiva and to the proximal margin of the mesofemur by the mesotrochantero-mesofemoral conjunctiva." [] {term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0004168 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! trochanter relationship: AISM:0000078 AISM:0004176 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles mesotrochantero-mesofemoral conjunctiva relationship: AISM:0000079 AISM:0000124 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by mesocoxal-mesotrochanteral conjunctiva relationship: BFO:0000050 AISM:0000035 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of mid leg property_value: IAO:0000589 "cuticle of mesotrochanter" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004173 name: metatrochanter {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of a hind leg attached to the distal margin of the metacoxa by the metacoxal-metatrochanteral conjunctiva and to the proximal margin of the metafemur by the metatrochantero-metafemoral conjunctiva." [] {term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0004168 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! trochanter relationship: AISM:0000078 AISM:0004177 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles metatrochantero-metafemoral conjunctiva relationship: AISM:0000079 AISM:0000125 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by metacoxal-metatrochanteral conjunctiva relationship: BFO:0000050 AISM:0000036 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of hind leg property_value: IAO:0000589 "cuticle of metatrochanter" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004174 name: trochantero-femoral conjunctiva def: "The conjunctiva that encircles the femur by joining the distal margin of the trochanter and the proximal margin of the femur." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0000102 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! ring conjunctiva relationship: AISM:0000078 AISM:0000076 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles femur relationship: BFO:0000050 AISM:0000031 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect leg [Term] id: AISM:0004175 name: protrochantero-profemoral conjunctiva def: "The conjunctiva that encircles the profemur by joining the distal margin of the protrochanter and the proximal margin of the profemur." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0004174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! trochantero-femoral conjunctiva relationship: AISM:0000078 AISM:0000070 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles profemur relationship: BFO:0000050 AISM:0000034 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of fore leg [Term] id: AISM:0004176 name: mesotrochantero-mesofemoral conjunctiva def: "The conjunctiva that encircles the mesofemur by joining the distal margin of the mesotrochanter and the proximal margin of the mesofemur." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0004174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! trochantero-femoral conjunctiva relationship: AISM:0000078 AISM:0000071 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles mesofemur relationship: BFO:0000050 AISM:0000035 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of mid leg [Term] id: AISM:0004177 name: metatrochantero-metafemoral conjunctiva def: "The conjunctiva that encircles the metafemur by joining the distal margin of the metatrochanter and the proximal margin of the metafemur." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0004174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! trochantero-femoral conjunctiva relationship: AISM:0000078 AISM:0000072 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles metafemur relationship: BFO:0000050 AISM:0000036 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of hind leg [Term] id: AISM:0004178 name: femoro-tibial conjunctiva def: "The conjunctiva that encircles the tibia by joining the distal margin of the femur and the proximal margin of the tibia." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0000102 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! ring conjunctiva relationship: AISM:0000078 AISM:0000075 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles tibia relationship: AISM:0000079 AISM:0000076 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by femur relationship: BFO:0000050 AISM:0000031 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect leg [Term] id: AISM:0004179 name: profemoro-protibial conjunctiva def: "The conjunctiva that encircles the protibia by joining the distal margin of the profemur and the proximal margin of the protibia." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0004178 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! femoro-tibial conjunctiva relationship: AISM:0000078 AISM:0000067 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles protibia relationship: AISM:0000079 AISM:0000070 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by profemur relationship: BFO:0000050 AISM:0000034 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of fore leg [Term] id: AISM:0004180 name: mesofemoro-mesotibial conjunctiva def: "The conjunctiva that encircles the mesotibia by joining the distal margin of the mesofemur and the proximal margin of the mesotibia." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0004178 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! femoro-tibial conjunctiva relationship: AISM:0000078 AISM:0000068 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles mesotibia relationship: AISM:0000079 AISM:0000071 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by mesofemur relationship: BFO:0000050 AISM:0000035 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of mid leg [Term] id: AISM:0004181 name: metafemoro-metatibial conjunctiva def: "The conjunctiva that encircles the metatibia by joining the distal margin of the metafemur and the proximal margin of the metatibia." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0004178 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! femoro-tibial conjunctiva relationship: AISM:0000078 AISM:0000069 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles metatibia relationship: AISM:0000079 AISM:0000072 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by metafemur relationship: BFO:0000050 AISM:0000036 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of hind leg [Term] id: AISM:0004182 name: tibio-tarsal conjunctiva def: "The conjunctiva that encircles the tarsus by joining the distal margin of the tibia and the proximal margin of the tarsus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0000102 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! ring conjunctiva relationship: AISM:0000078 AISM:0004169 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles tarsus relationship: AISM:0000079 AISM:0000075 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by tibia relationship: BFO:0000050 AISM:0000031 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect leg [Term] id: AISM:0004183 name: protibio-protarsal conjunctiva def: "The conjunctiva that encircles the protarsus by joining the distal margin of the protibia and the proximal margin of the protarsus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0004182 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tibio-tarsal conjunctiva relationship: AISM:0000078 AISM:0004190 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles protarsus relationship: AISM:0000079 AISM:0000067 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by protibia relationship: BFO:0000050 AISM:0000034 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of fore leg [Term] id: AISM:0004184 name: mesotibio-mesotarsal conjunctiva def: "The conjunctiva that encircles the mesotarsus by joining the distal margin of the mesotibia and the proximal margin of the mesotarsus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0004182 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tibio-tarsal conjunctiva relationship: AISM:0000078 AISM:0004189 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles mesotarsus relationship: AISM:0000079 AISM:0000068 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by mesotibia relationship: BFO:0000050 AISM:0000035 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of mid leg [Term] id: AISM:0004185 name: metatibio-metatarsal conjunctiva def: "The conjunctiva that encircles the metatarsus by joining the distal margin of the metatibia and the proximal margin of the metatarsus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0004182 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tibio-tarsal conjunctiva relationship: AISM:0000078 AISM:0004188 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles metatarsus relationship: AISM:0000079 AISM:0000069 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by metatibia relationship: BFO:0000050 AISM:0000036 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of hind leg [Term] id: AISM:0004186 name: mesopleuron def: "The region of the cuticle on the lateral region of the mesothorax that is attached to the mesonotum and the mesosternum, and is attached to the mesocoxa by the mesocoxal muscle and the basal mesocoxal conjunctiva." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004129 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pleuron relationship: RO:0002150 AISM:0000085 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with mesocoxal muscle relationship: RO:0002150 AISM:0000103 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with basal mesocoxal conjunctiva relationship: RO:0002220 AISM:0000052 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to mesonotum relationship: RO:0002220 AISM:0000121 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to mesosternum [Term] id: AISM:0004187 name: tarso-distitarsal conjunctiva {IAO:0000232="Modified 2026-02-14: Updated to distitarsal to match with updated distitarsus.\njgiron https://orcid.org/0000-0002-0851-6883"} def: "The conjunctiva that encircles the distitarsus by joining the distal margin of the distalmost tarsomere and the proximal margin of the distitarsus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0000102 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! ring conjunctiva relationship: AISM:0000078 AISM:0000047 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles distitarsus relationship: AISM:0000079 AISM:0004169 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by tarsus relationship: BFO:0000050 AISM:0000031 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect leg [Term] id: AISM:0004188 name: metatarsus {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of the leg that is composed of metatarsomeres connected to each other by intertarsomeral conjunctiva. The first metatarsomere is connected to the distal margin of the metatibia by the metatibio-metatarsal conjunctiva." [] {term:modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0004169 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tarsus relationship: AISM:0000079 AISM:0004185 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by metatibio-metatarsal conjunctiva relationship: BFO:0000050 AISM:0000036 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of hind leg property_value: IAO:0000589 "cuticle of metatarsus" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004189 name: mesotarsus {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of the mid leg that is composed of mesotarsomeres connected to each other by intertarsomeral conjunctiva. The first mesotarsomere is connected to the distal margin of the mesotibia by the mesotibio-mesotarsal conjunctiva." [] {term:modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0004169 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tarsus relationship: AISM:0000079 AISM:0004184 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by mesotibio-mesotarsal conjunctiva property_value: IAO:0000589 "cuticle of mesotarsus" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004190 name: protarsus {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of the leg that is composed of protarsomeres connected to each other by intertarsomeral conjunctiva. The first protarsomere is connected to the distal margin of the protibia by the protibio-protarsal conjunctiva." [] {term:modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0004169 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tarsus relationship: AISM:0000079 AISM:0004183 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by protibio-protarsal conjunctiva relationship: BFO:0000050 AISM:0000034 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of fore leg property_value: IAO:0000589 "cuticle of protarsus" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004191 name: protarso-prodistitarsal conjunctiva {IAO:0000232="Modified 2026-02-14: Updated to distitarsus.\njgiron https://orcid.org/0000-0002-0851-6883"} def: "The conjunctiva that encircles the prodistitarsus by joining the distal margin of the distalmost protarsomere and the proximal margin of the prodistitarsus." [] {IAO:0000232="Modified 2026-02-14: Updated to distitarsus.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0004187 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tarso-distitarsal conjunctiva relationship: AISM:0000078 AISM:0004194 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles prodistitarsus relationship: AISM:0000079 AISM:0004190 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by protarsus [Term] id: AISM:0004192 name: mesotarso-mesodistitarsal conjunctiva {IAO:0000232="Modified 2026-02-14: Updated to distitarsus.\njgiron https://orcid.org/0000-0002-0851-6883"} def: "The conjunctiva that encircles the mesodistitarsus by joining the distal margin of the distalmost mesotarsomere and the proximal margin of the mesodistitarsus." [] {IAO:0000232="Modified 2026-02-14: Updated to distitarsus.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0004187 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tarso-distitarsal conjunctiva relationship: AISM:0000078 AISM:0004195 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles mesodistitarsus relationship: AISM:0000079 AISM:0004189 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by mesotarsus [Term] id: AISM:0004193 name: metatarso-metadistitarsal conjunctiva {IAO:0000232="Modified 2026-02-14: Updated to distitarsus.\njgiron https://orcid.org/0000-0002-0851-6883"} def: "The conjunctiva that encircles the metadistitarsus by joining the distal margin of the distalmost metatarsomere and the proximal margin of the metadistitarsus." [] {IAO:0000232="Modified 2026-02-14: Updated to distitarsus.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0004187 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tarso-distitarsal conjunctiva relationship: AISM:0000078 AISM:0004196 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles metadistitarsus relationship: AISM:0000079 AISM:0004188 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by metatarsus [Term] id: AISM:0004194 name: prodistitarsus {IAO:0000232="Modified 2026-02-14: Updated to distitarsus.\njgiron https://orcid.org/0000-0002-0851-6883", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the appendage of the fore leg that is attached to the protarsus by the protarso-prodistitarsal conjunctiva." [] {IAO:0000232="Modified 2026-02-14: Updated to distitarsus.\njgiron https://orcid.org/0000-0002-0851-6883", term:modified="2021-12-10", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0000047 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! distitarsus relationship: BFO:0000050 AISM:0000034 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of fore leg relationship: RO:0002150 AISM:0004191 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with protarso-prodistitarsal conjunctiva property_value: IAO:0000589 "cuticle of prodistitarsus" xsd:string {IAO:0000232="Modified 2026-02-14: Updated to distitarsus.\njgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-04-13"} [Term] id: AISM:0004195 name: mesodistitarsus {IAO:0000232="Modified 2026-02-14: Updated to distitarsus.\njgiron https://orcid.org/0000-0002-0851-6883", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the appendage of the mid leg that is attached to the mesotarsus by the mesotarso-mesodistitarsal conjunctiva." [] {term:modified="2021-12-10", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0000047 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! distitarsus relationship: BFO:0000050 AISM:0000035 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of mid leg relationship: RO:0002150 AISM:0004192 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with mesotarso-mesodistitarsal conjunctiva property_value: IAO:0000589 "cuticle of mesodistitarsus" xsd:string {IAO:0000232="Modified 2026-02-14: Updated to distitarsus.\njgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-04-13"} [Term] id: AISM:0004196 name: metadistitarsus {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the appendage of the hind leg that is attached to the distitarsus by the metatarso-metadistitarsal conjunctiva." [] {IAO:0000232="Modified 2026-02-14: Updated to distitarsus.\njgiron https://orcid.org/0000-0002-0851-6883", term:modified="2021-12-10", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0000047 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! distitarsus relationship: BFO:0000050 AISM:0000036 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of hind leg relationship: RO:0002150 AISM:0004193 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with metatarso-metadistitarsal conjunctiva property_value: IAO:0000589 "cuticle of metadistitarsus" xsd:string {IAO:0000232="Modified 2026-02-14: Updated to distitarsus.\njgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-04-13"} [Term] id: AISM:0004197 name: insect anus def: "The orifice on the postabdomen at the posterior margin of the digestive tract, connected to the epiproct and paraprocti." [] {creation_date="2021-04-10", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: UBERON:0000161 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! orifice relationship: AISM:0000079 AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by postabdomen relationship: RO:0002220 AISM:0004060 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to epiproct relationship: RO:0002220 AISM:0004061 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to paraproct [Term] id: AISM:0004198 name: gonostylus IX {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The region of the cuticle of the postabdomen that is paired and connected to the anterior region of the gonocoxa IX." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: BFO:0000050 AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of postabdomen relationship: RO:0000053 PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has characteristic bilaterally paired property_value: IAO:0000589 "cuticle of gonostylus IX" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004199 name: cercomere {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the mere that is part of the cercus." [] {term:modified="2021-12-08", creation_date="2021-08-04", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000073 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mere relationship: BFO:0000050 AISM:0004165 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of cercus property_value: IAO:0000589 "cuticle of cercomere" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004200 name: paramero-aedeagal conjunctiva def: "The conjunctiva of the postabdomen that joins the parameres and the aedeagus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: BFO:0000050 AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of postabdomen relationship: RO:0002150 AISM:0004062 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with aedeagus relationship: RO:0002150 AISM:0004064 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with paramere [Term] id: AISM:0004201 name: phallobasal-parameral conjunctiva def: "The conjunctiva of the postabdomen that joins the phallobase and the parameres." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: BFO:0000050 AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of postabdomen relationship: RO:0002150 AISM:0004064 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with paramere relationship: RO:0002150 AISM:0004065 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with phallobase [Term] id: AISM:0004202 name: propleuro-prosternal conjunctiva def: "The conjunctiva of the prothorax that joins the propleura and the prosternum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: BFO:0000050 AISM:0004125 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of prothorax relationship: RO:0002150 AISM:0000061 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with prosternum relationship: RO:0002150 AISM:0004142 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with propleuron [Term] id: AISM:0004203 name: basal wing conjunctiva def: "The conjunctiva of the pterothorax that surrounds the wing." [] {creation_date="2021-04-10", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: AISM:0000078 AISM:0000033 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircles insect wing relationship: BFO:0000050 AISM:0004166 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of pterothorax [Term] id: AISM:0004204 name: tergo-trochantinal muscle def: "The insect thoracic muscle that attaches to the notum and to the trochantin." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0002065 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect thoracic muscle relationship: RO:0002371 AISM:0004128 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! attached to notum relationship: RO:0002371 AISM:0004135 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! attached to trochantin property_value: IAO:0000232 "For muscular terminology, tergum has been traditionally used instead of notum, even though \"notum\" is the prererred term to refer to the dorsal region of the cuticle of the insect thorax that is attached to the dorsal margin of the pleuron." xsd:string {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} [Term] id: AISM:0004205 name: pronoto-protrochantinal muscle def: "The tergo-trochantinal muscle that is attached to the pronotum and the protrochantin." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0004204 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tergo-trochantinal muscle relationship: RO:0002371 AISM:0000055 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! attached to protrochantin relationship: RO:0002371 AISM:0000059 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! attached to pronotum [Term] id: AISM:0004206 name: mesonoto-mesotrochantinal muscle def: "The tergo-trochantinal muscle that is attached to the mesonotum and the mesotrochantin." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0004204 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! tergo-trochantinal muscle relationship: RO:0002371 AISM:0000052 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! attached to mesonotum relationship: RO:0002371 AISM:0000054 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! attached to mesotrochantin [Term] id: AISM:0004207 name: metanoto-metatrochantinal muscle def: "The tergo-trochantinal muscle that is attached to the metanotum and the metatrochantin." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0004204 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tergo-trochantinal muscle relationship: RO:0002371 AISM:0000056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! attached to metatrochantin relationship: RO:0002371 AISM:0000169 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! attached to metanotum [Term] id: AISM:0004208 name: tergo-tergal muscle def: "The insect thoracic muscle that extends between two nota (or terga)." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0002065 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect thoracic muscle relationship: RO:0002371 AISM:0004128 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! attached to notum [Term] id: AISM:0004209 name: pronoto-mesonotal muscle def: "The insect thoracic muscle that extends between the pronotum and the mesonotum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0004208 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! tergo-tergal muscle relationship: RO:0002371 AISM:0000052 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! attached to mesonotum relationship: RO:0002371 AISM:0000059 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! attached to pronotum [Term] id: AISM:0004210 name: mesonoto-metanotal muscle def: "The insect thoracic muscle that extends between the mesonotum and the metanotum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0004208 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! tergo-tergal muscle relationship: RO:0002371 AISM:0000052 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! attached to mesonotum relationship: RO:0002371 AISM:0000169 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! attached to metanotum [Term] id: AISM:0004211 name: tergo-coxal muscle def: "The insect thoracic muscle that extends between the notum (or tergum) and the coxa." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0002065 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect thoracic muscle relationship: RO:0002371 AISM:0000077 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! attached to coxa relationship: RO:0002371 AISM:0004128 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! attached to notum [Term] id: AISM:0004212 name: tergo-trochanteral muscle def: "The insect thoracic muscle that extends between the notum (or tergum) and the trochanter." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0002065 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect thoracic muscle relationship: RO:0002371 AISM:0004128 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! attached to notum relationship: RO:0002371 AISM:0004168 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! attached to trochanter [Term] id: AISM:0004213 name: pleuro-coxal muscle def: "The insect thoracic muscle that attaches to the pleuron and to a coxa." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0002065 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect thoracic muscle relationship: RO:0002371 AISM:0000077 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! attached to coxa relationship: RO:0002371 AISM:0004129 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! attached to pleuron [Term] id: AISM:0004214 name: furco-coxal muscle def: "The insect thoracic muscle that is attached to a furca and to a coxa." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-08"} is_a: AISM:0002065 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect thoracic muscle relationship: RO:0002371 AISM:0000077 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! attached to coxa relationship: RO:0002371 AISM:0000144 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! attached to furca [Term] id: AISM:0004215 name: furco-trochanteral muscle def: "The insect thoracic muscle that is attached to a furca and to a trochanter." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-08"} is_a: AISM:0002065 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect thoracic muscle relationship: RO:0002371 AISM:0000144 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! attached to furca relationship: RO:0002371 AISM:0004168 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! attached to trochanter [Term] id: AISM:0004216 name: interfurcal muscle def: "The insect thoracic muscle that extends between two furcae." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0002065 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect thoracic muscle relationship: RO:0002371 AISM:0000144 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! attached to furca [Term] id: AISM:0004217 name: profurco-mesofurcal muscle def: "The insect thoracic muscle that extends between the profurca and the mesofurca." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0004216 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! interfurcal muscle relationship: RO:0002371 AISM:0000141 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! attached to mesofurca relationship: RO:0002371 AISM:0000143 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! attached to profurca [Term] id: AISM:0004218 name: mesofurco-metafurcal muscle def: "The insect thoracic muscle that extends between the mesofurca and the metafurca." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0004216 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! interfurcal muscle relationship: RO:0002371 AISM:0000141 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! attached to mesofurca relationship: RO:0002371 AISM:0000142 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! attached to metafurca [Term] id: AISM:0004219 name: mesonoto-mesopleural conjuntiva def: "The noto-pleural conjunctiva that joins the mesonotum and the mesopleuron." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0004222 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! noto-pleural conjunctiva relationship: RO:0002150 AISM:0000052 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with mesonotum relationship: RO:0002150 AISM:0004186 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with mesopleuron [Term] id: AISM:0004220 name: pronoto-propleural conjunctiva def: "The noto-pleural conjunctiva that joins the pronotum and the propleuron." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0004222 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! noto-pleural conjunctiva relationship: RO:0002150 AISM:0000059 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with pronotum relationship: RO:0002150 AISM:0004142 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with propleuron [Term] id: AISM:0004221 name: metanoto-metapleural conjunctiva def: "The noto-pleural conjunctiva that joins the metanotum and the metapleuron." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0004222 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! noto-pleural conjunctiva relationship: RO:0002150 AISM:0000119 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with metapleuron relationship: RO:0002150 AISM:0000169 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with metanotum [Term] id: AISM:0004222 name: noto-pleural conjunctiva def: "The conjunctiva of the insect thorax that joins the notum and the pleuron." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: BFO:0000050 AISM:0000108 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect thorax relationship: RO:0002150 AISM:0004128 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with notum relationship: RO:0002150 AISM:0004129 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with pleuron [Term] id: AISM:0004223 name: third axillary sclerite def: "The axillary sclerite that is connected via muscle to the mesopleuron and is posterior to the first axillary sclerite." [] {creation_date="2021-04-10", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004161 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! axillary sclerite relationship: BSPO:0000099 AISM:0000022 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! posterior to first axillary sclerite [Term] id: AISM:0004224 name: ventral second axillary sclerite def: "The axillary sclerite that is on the ventral region of the basal wing conjunctiva." [] {creation_date="2021-04-10", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004161 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! axillary sclerite [Term] id: AISM:0004225 name: mesophragma def: "The phragma of the metanotum that attaches to muscles attached to the mesonotum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0002048 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! phragma relationship: BFO:0000050 AISM:0000169 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of metanotum [Term] id: AISM:0004226 name: mesophragmo-abdominal tergite I muscle def: "The insect thoracic muscle that extends between the mesophragma and the abdominal tergite I." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0004208 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! tergo-tergal muscle relationship: RO:0002371 AISM:0000021 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! attached to abdominal tergite I relationship: RO:0002371 AISM:0004225 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! attached to mesophragma [Term] id: AISM:0004227 name: metafurco-abdominal sternite muscle def: "The insect thoracic muscle that extends between the metafurca and an abdominal sternite." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0002065 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect thoracic muscle relationship: RO:0002371 AISM:0000142 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! attached to metafurca relationship: RO:0002371 AISM:0004058 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! attached to abdominal sternite [Term] id: AISM:0004228 name: metaphragma def: "The phragma of the abdominal tergite I that attaches to muscles attached to the metanotum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0002048 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! phragma relationship: BFO:0000050 AISM:0000021 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of abdominal tergite I [Term] id: AISM:0004229 name: mesonoto-metanotal conjunctiva def: "The conjunctiva of the insect thorax that joins the mesonotum and the metanotum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: BFO:0000050 AISM:0000108 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect thorax relationship: RO:0002150 AISM:0000052 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with mesonotum relationship: RO:0002150 AISM:0000169 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with metanotum [Term] id: AISM:0004230 name: mesopleuro-mesocoxal conjunctiva def: "The conjunctiva of the mesothorax that joins the mesopleuron and the mesocoxa." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: BFO:0000050 AISM:0004126 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of mesothorax relationship: RO:0002150 AISM:0000064 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with mesocoxa relationship: RO:0002150 AISM:0004186 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with mesopleuron [Term] id: AISM:0004231 name: mesopleuro-mesosternal conjunctiva def: "The conjunctiva of the mesothorax that joins the mesopleura and the mesosternum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: BFO:0000050 AISM:0004125 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of prothorax relationship: RO:0002150 AISM:0000061 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with prosternum relationship: RO:0002150 AISM:0004186 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with mesopleuron [Term] id: AISM:0004232 name: metasternum def: "The sclerite on the ventral region of the metathorax that bears the metafurca and is attached to the metapleuro-metasternal conjunctiva." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0004130 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! sternum relationship: BFO:0000051 AISM:0000142 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part metafurca relationship: RO:0002150 AISM:0004101 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with metapleuro-metasternal conjunctiva [Term] id: AISM:0004233 name: mesosterno-mesocoxal conjunctiva def: "The conjunctiva of the mesothorax that joins the mesosternum and the mesocoxa." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: BFO:0000050 AISM:0004126 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of mesothorax relationship: RO:0002150 AISM:0000064 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with mesocoxa relationship: RO:0002150 AISM:0000121 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! continuous with mesosternum [Term] id: AISM:0004234 name: circular pouch {creation_date="2021-07-21"} def: "The pouch that is circular." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-07-21"} is_a: AISM:0000160 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular pouch relationship: RO:0000053 PATO:0000411 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! has characteristic circular [Term] id: AISM:0004235 name: ectodermal gland {AISM:0000171="Snodgrass RE (1993) Principles of Insect Morphology. Cornell University Press, 768 pp.\n\nhttps://www.jstor.org/stable/10.7591/j.ctv1nhm1j\n\n\"cells or groups of cells with highly specialized secretory functions, producing a great variety of substances which are discharged at the exterior or into invaginations of the body wall\""} def: "The region of cuticle that is continuous with glandular epithelial cells." [] {creation_date="2021-08-17", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: RO:0002150 CL:0000150 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! continuous with glandular epithelial cell [Term] id: AISM:0004236 name: unicellular ectodermal gland {AISM:0000171="Snodgrass RE (1993) Principles of Insect Morphology. Cornell University Press, 768 pp.\n\nhttps://www.jstor.org/stable/10.7591/j.ctv1nhm1j\n\n\"one-celled gland usually larger than the cells surrounding it; discharges its products directly through the covering cuticula. [...] In many glands a minute cuticular ductule extends from the exterior into the body of each cell, allowing the secretion to pass out through an extremely thin layer of cuticula.\""} def: "The ectodermal gland that is composed of one cell" [] {creation_date="2021-08-16", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004235 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! ectodermal gland relationship: BFO:0000051 CL:0000000 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part cell [Term] id: AISM:0004237 name: cuticular lobe {term:modified="2021-12-08", AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"a rounded projection or protuberance\""} def: "The cuticular evagination that is largely membranous." [] {creation_date="2021-06-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000128 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-06-14"} ! multicellular cuticular evagination relationship: BFO:0000051 AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-06-14"} ! has part conjunctiva [Term] id: AISM:0004238 name: multicellular ectodermal gland {AISM:0000171="Snodgrass RE (1993) Principles of Insect Morphology. Cornell University Press, 768 pp.\n\nhttps://www.jstor.org/stable/10.7591/j.ctv1nhm1j\n\n\"many-celled glands may be a group of cells situated at the surface of the body, but most of them are invaginations of the body wall.\""} def: "The ectodermal gland that is composed of multiple cells." [] {creation_date="2021-08-16", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004235 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! ectodermal gland [Term] id: AISM:0004239 name: occiput {AISM:0000171="Snodgrass RE (1993) Principles of Insect Morphology. Cornell University Press, 768 pp.\n\nhttps://www.jstor.org/stable/10.7591/j.ctv1nhm1j\n\n\"dorsal part of the posterior surface of the head between the occipital and the postoccipital sutures\""} def: "The region of cuticle on the posterodorsal region of the head capsule that is posterior to the occipital ridge and anterior to the postoccipital ridge." [] {creation_date="2021-08-16", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: BSPO:0000096 AISM:0004021 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anterior to postoccipital ridge relationship: BSPO:0000099 AISM:0004048 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! posterior to occipital ridge [Term] id: AISM:0004240 name: epicranial suture {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Y-shaped ecdysial sutures dividing vertex and frons, composed of\ncoronal suture and paired frontal sutures.\""} def: "The cuticular suture composed of both the coronal suture and paired frontal sutures." [] {creation_date="2021-08-16", term:modified="2021-12-10", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004028 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular suture relationship: BFO:0000051 AISM:0004029 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part frontal suture relationship: BFO:0000051 AISM:0004030 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part coronal suture [Term] id: AISM:0004241 name: temple {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"the part of the head above and behind the compound eyes\""} def: "The region of cuticle that is behind the compound eye." [] {creation_date="2021-08-16", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: BSPO:0000099 AISM:0004052 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! posterior to insect compound eye [Term] id: AISM:0004242 name: insect wing region {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"the principal areas of the wings differentiated in the wing-flexing insects (Neoptera), and often separated by distinct lines of folding, including the wing base, remigium, clavus, and jugum.\""} def: "The region of cuticle of the insect wing that has wing veins, folds, and conjunctiva." [] {creation_date="2021-09-07", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: BFO:0000051 AISM:0004243 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part insect wing vein relationship: BFO:0000051 AISM:0004244 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has part insect wing fold [Term] id: AISM:0004243 name: insect wing vein {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"sclerotized, tubular structure supporting the membrane of the wings\""} def: "The region of cuticle of the insect wing that is less flexible than the wing conjunctiva." [] {creation_date="2021-09-07", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: BFO:0000050 AISM:0000033 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect wing [Term] id: AISM:0004244 name: insect wing fold {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"line along which wings fold at rest\""} def: "The region of cuticle of the insect wing that is more flexible than the wing conjunctiva." [] {creation_date="2021-09-07", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: BFO:0000050 AISM:0000033 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of insect wing [Term] id: AISM:0004245 name: anal field of the insect wing {IAO:0000232="Modified 2023-01-21: specifying insect wing field.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Anal field (=vannus): posterior part of wings, usually enlarged in Polyneoptera.\""} def: "The posterior region of the insect wing." [] {creation_date="2021-09-07", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} synonym: "vannus" EXACT [] is_a: AISM:0004242 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing region relationship: BSPO:0000099 AISM:0004311 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! posterior to cubital field of the insect wing [Term] id: AISM:0004246 name: anal vein of the insect wing {IAO:0000232="Modified 2023-01-09: specifying insect wing vein.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Anal veins: longitudinal veins of the anal field proximally articulated with 3rd axillary sclerite; usually unbranched and arranged like a fan.\""} def: "The insect wing vein of the anal field that is posterior to the anal fold or the postcubitus and anterior to the jugal fold or the jugal veins." [] {creation_date="2021-09-07", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004243 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing vein relationship: RO:0001018 AISM:0004245 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! obsolete contained in anal field of the insect wing [Term] id: AISM:0004247 name: costal vein of the insect wing {IAO:0000232="Modified 2023-01-09: specifying insect wing vein.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Costa: main longitudinal vein along anterior wing margin, articulated with humeral plate.\""} def: "The insect wing vein of the costal field that is anterior to the subcosta." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004243 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing vein relationship: BSPO:0000096 AISM:0004257 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anterior to subcostal vein of the insect wing relationship: RO:0001018 AISM:0004248 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! obsolete contained in costal field of the insect wing [Term] id: AISM:0004248 name: costal field of the insect wing {IAO:0000232="Modified 2023-01-21: specifying insect wing field.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Costal field (=remigium): anterior part of wing; usually largest region.\""} def: "The anterior region of the insect wing." [] {creation_date="2021-09-07", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} synonym: "remigium" EXACT [] is_a: AISM:0004242 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing region is_a: BSPO:0000078 ! distal region [Term] id: AISM:0004249 name: cubital vein of the insect wing {IAO:0000232="Modified 2023-01-09: specifying insect wing vein.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Cubitus: 5th main longitudinal vein.\""} def: "The insect wing vein that is posterior to the media and anterior to the postcubitus." [] {creation_date="2021-09-07", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004243 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing vein relationship: BSPO:0000096 AISM:0004255 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anterior to postcubital vein of the insect wing relationship: BSPO:0000099 AISM:0004252 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! posterior to medial vein of the insect wing [Term] id: AISM:0004250 name: jugal field of the insect wing {IAO:0000232="Modified 2023-01-21: specifying insect wing field.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Jugal field: small wing region posteriorly adjacent with anal field.\""} def: "The insect wing region that is posterior to the jugal fold." [] {creation_date="2021-09-07", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004242 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing region relationship: BSPO:0000099 AISM:0004253 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! posterior to jugal fold of the insect wing [Term] id: AISM:0004251 name: jugal vein of the insect wing {IAO:0000232="Modified 2023-01-09: specifying insect wing vein.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Jugal veins: veins of the jugal field.\""} def: "The insect wing vein in the jugal field, posterior to the jugal fold or to the anal veins." [] {creation_date="2021-09-07", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004243 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing vein relationship: RO:0001018 AISM:0004250 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! obsolete contained in jugal field of the insect wing [Term] id: AISM:0004252 name: medial vein of the insect wing {IAO:0000232="Modified 2023-01-09: specifying insect wing vein.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Media: 4th main longitudinal vein.\""} def: "The insect wing vein that is posterior to some radius and anterior to some cubitus." [] {creation_date="2021-09-07", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004243 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing vein relationship: BSPO:0000096 AISM:0004249 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anterior to cubital vein of the insect wing relationship: BSPO:0000099 AISM:0004256 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! posterior to radial vein of the insect wing [Term] id: AISM:0004253 name: jugal fold of the insect wing {IAO:0000232="Modified 2023-01-21: specifying insect wing fold.\njgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect wing fold that separates the anal field and the jugal field." [] {creation_date="2021-09-07", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} synonym: "plica jugalis" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Plica jugalis: separates the anal and jugal fields.\""} is_a: AISM:0004244 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing fold [Term] id: AISM:0004254 name: anal fold of the insect wing {IAO:0000232="Modified 2023-01-21: specifying insect wing fold.\njgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect wing fold that is posterior to the postcubitus and separates the costal field and the anal field." [] {creation_date="2021-09-07", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} synonym: "claval furrow" EXACT [] {AISM:0000171="Chapman RF (2012) The Insects: Structure and Function. Fifth Edition. Cambridge University Press. 959 pp. \n\nhttps://doi.org/10.1017/CBO9781139035460\n\n\"longitudinal flexion line which runs close to the CuP. This furrow allows the posterior part of the wing to flap up and down with respect to the rest of the wing.\""} synonym: "plica vannalis" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Plica vannalis: separates the costal and anal fields.\""} is_a: AISM:0004244 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing fold relationship: BSPO:0000099 AISM:0004255 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! posterior to postcubital vein of the insect wing [Term] id: AISM:0004255 name: postcubital vein of the insect wing {IAO:0000232="Modified 2023-01-09: specifying insect wing vein.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Postcubitus: posteriormost longitudinal vein of the remigium.\""} def: "The insect wing vein that is posterior to the cubitus and anterior to the anal fold or the anal vein." [] {creation_date="2021-09-07", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004243 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing vein relationship: BSPO:0000099 AISM:0004249 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! posterior to cubital vein of the insect wing [Term] id: AISM:0004256 name: radial vein of the insect wing {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Radius: 3rd main longitudinal vein.\"", IAO:0000232="Modified 2023-01-09: specifying insect wing vein.\njgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect wing vein that is posterior to the subcosta and anterior to the media." [] {creation_date="2021-09-07", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004243 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing vein relationship: BSPO:0000096 AISM:0004252 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anterior to medial vein of the insect wing relationship: BSPO:0000099 AISM:0004257 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! posterior to subcostal vein of the insect wing [Term] id: AISM:0004257 name: subcostal vein of the insect wing {IAO:0000232="Modified 2023-01-09: specifying insect wing vein.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Subcosta: 2nd main longitudinal vein, following costal vein.\""} def: "The insect wing vein that is posterior to the costa and anterior to the radius." [] {creation_date="2021-09-07", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004243 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing vein relationship: BSPO:0000096 AISM:0004256 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anterior to radial vein of the insect wing relationship: BSPO:0000099 AISM:0004247 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! posterior to costal vein of the insect wing [Term] id: AISM:0004258 name: axillary region of the insect wing {IAO:0000232="Modified 2023-01-21: specifying insect wing region.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Snodgrass RE (1993) Principles of Insect Morphology. Cornell University Press, 768 pp.\n\nhttps://www.jstor.org/stable/10.7591/j.ctv1nhm1j\n\n\"The region of the wing base containing the axillary sclerites\""} def: "The proximal region of the insect wing." [] {creation_date="2021-09-07", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004242 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing region is_a: BSPO:0000078 ! distal region [Term] id: AISM:0004259 name: basal fold of the insect wing {comment="Modified 2023-01-21: specifying insect wing fold.\njgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect wing fold that is distal to the axillary region." [] {creation_date="2021-09-07", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} synonym: "plica basalis" EXACT [] {AISM:0000171="Snodgrass RE (1993) Principles of Insect Morphology. Cornell University Press, 768 pp.\n\nhttps://www.jstor.org/stable/10.7591/j.ctv1nhm1j\n\n\"Plica basalis (bf).The basal fold of the wing, or line of flection between the base of the mediocubital fold and the axillary region, forming a prominent convex fold in the flexed wing extending between the median plates from the articulation of radius with the second axillary to the articulation of the vannal veins with the third axillary.\""} is_a: AISM:0004244 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing fold relationship: BSPO:0000097 AISM:0004258 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! distal to axillary region of the insect wing [Term] id: AISM:0004260 name: distitarsal claw {IAO:0000232="Modified 2026-02-14: Updated to distitarsal.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Ungues: pretarsal claws; unpaired in Collembola and Protura, usually paired in Diplura and Insecta.\""} def: "The sclerite that is part of the distitarsus." [] {IAO:0000232="Modified 2026-02-14: Updated to distitarsus.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-11-19"} synonym: "pretarsal claw" EXACT [] synonym: "ungues" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Ungues: pretarsal claws; unpaired in Collembola and Protura, usually paired in Diplura and Insecta.\""} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: BFO:0000050 AISM:0000047 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of distitarsus [Term] id: AISM:0004261 name: empodium {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Empodium: a median process between the claws and pulvilli (if present). It arises from the distal end of the unguitractor plate, is spine-shaped or lobe-like and is sometimes similar in form to the pulvilli (“empodial pulvillus”).\" p. 43.", AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"a spine- or lobelike process of the unguitractor\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticular protrusion that is part of the distitarsus, ventral to the distitarsal claws and medial to the pulvilli (if present)." [] {IAO:0000232="Modified 2026-02-14: Updated to distitarsus.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-11-19", IAO:0000232="Modified 2023-01-11: added medial to pulvilli.\njgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000008 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular protrusion relationship: AISM:0000012 AISM:0004308 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! medial_to pulvillus relationship: BFO:0000050 AISM:0000047 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of distitarsus relationship: BSPO:0000102 AISM:0004260 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! ventral to distitarsal claw property_value: IAO:0000589 "cuticle of empodium" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004262 name: frontoclypeal sulcus def: "The sulcus that coincides with the frontoclypeal ridge and separated the frons from the clypeus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-11-19"} synonym: "epistomal sulcus" EXACT [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} synonym: "epistomal suture" EXACT [] {AISM:0000171="Lawrence J, Ślipiński A (2013) Adult morphology. In: Australian beetles volume 1: morphology, classification and keys. CSIRO Publishing, 30–63. \n\nhttps://www.publish.csiro.au/book/6466/\n\n[adjusted] the 'suture' separating the clypeus from the frons, representing the internal invagination of the epistomal ridge."} synonym: "frontoclypeal suture" EXACT [] {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"the suture between the frons and the clypeus\""} is_a: AISM:0000162 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular sulcus relationship: RO:0002008 AISM:0004034 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! coincident with frontoclypeal ridge relationship: RO:0002220 AISM:0004019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to clypeus relationship: RO:0002220 AISM:0004020 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to frons [Term] id: AISM:0004263 name: cibarium {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Anterior part of preoral space between epipharynx and hypopharynx.\"", creation_date="2021-12-15"} def: "The conjunctiva that is part of the head capsule and is continuous with the epipharynx and the hypopharynx." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-12-15"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-12-15"} ! conjunctiva relationship: BFO:0000050 AISM:0000019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-12-15"} ! part of head capsule relationship: RO:0002150 AISM:0000093 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-12-15"} ! continuous with hypopharynx relationship: RO:0002150 AISM:0000105 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-12-15"} ! continuous with epipharynx [Term] id: AISM:0004264 name: epistoma {creation_date="2022-02-21", AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"the oral margin or sclerite directly behind the labrum\""} def: "The region of cuticle that is posterior to the cuticle of the labrum." [] {creation_date="2022-02-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-02-21"} ! insect region of cuticle relationship: BSPO:0000099 AISM:0000042 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-02-21"} ! posterior to labrum [Term] id: AISM:0004265 name: subgenal sulcus {creation_date="2022-02-21", AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"the lateral submarginal groove of the cranium just above the bases of the gnathal appendages, extending between the anterior tentorial pit and the posterior tentorial pit\""} def: "The cuticular sulcus that is adjacent to the subgena and coincides with the subgenal ridge." [] {creation_date="2022-02-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} synonym: "subgenal suture" EXACT [] is_a: AISM:0000162 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-02-21"} ! cuticular sulcus relationship: RO:0002008 AISM:0004032 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-02-21"} ! coincident with subgenal ridge relationship: RO:0002220 AISM:0004027 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-02-21"} ! adjacent to subgena [Term] id: AISM:0004266 name: antennomere {creation_date="2022-06-20", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of a mere that is part of the cuticle of the antenna." [] {creation_date="2022-06-20", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000073 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-20"} ! mere relationship: BFO:0000050 AISM:0000032 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-20"} ! part of antenna property_value: IAO:0000232 "Given the high number of antennomeres occurring in some taxa, Arabic numerals are used instead of Roman numerals for practicality reasons." xsd:string {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} property_value: IAO:0000589 "cuticle of antennomere" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004267 name: postoccipital sulcus {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n[as postoccipital suture] \"posterior submarginal groove having the posterior tentorial pits in its lower end, separatig the postocciput from the rest of the cranium\"", creation_date="2022-06-17"} def: "The cuticular sulcus that coincides with the postoccipital ridge and is posterior to the occiput and anterior to the postocciput." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-17"} synonym: "postoccipital suture" EXACT [] {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"posterior submarginal groove having the posterior tentorial pits in its lower end, separatig the postocciput from the rest of the cranium\""} is_a: AISM:0000162 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-17"} ! cuticular sulcus relationship: BSPO:0000096 AISM:0004045 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-17"} ! anterior to postocciput relationship: BSPO:0000099 AISM:0004239 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-17"} ! posterior to occiput relationship: RO:0002008 AISM:0004021 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-17"} ! coincident with postoccipital ridge [Term] id: AISM:0004268 name: gular sulcus {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n[as gular suture] \"the line or division between the gula and the genae\""} def: "The cuticular sulcus that coincides with the gular ridge, separating the gula fron the gena" [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-17"} synonym: "gular suture" EXACT [] {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"the line or division between the gula and the genae\""} is_a: AISM:0000162 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-17"} ! cuticular sulcus relationship: RO:0002008 AISM:0004036 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-17"} ! coincident with gular ridge relationship: RO:0002220 AISM:0004026 {x_1.1:contributor="2022-06-17", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! adjacent to gena relationship: RO:0002220 AISM:0004035 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-17"} ! adjacent to gula [Term] id: AISM:0004269 name: mandibular incisor lobe {creation_date="2022-06-20", AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"toothed distal lobe of mandible\""} def: "The region of the cuticle that is distal and medial on the cuticle of the insect mandible." [] {creation_date="2022-06-20", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-20"} ! insect region of cuticle [Term] id: AISM:0004270 name: mandibular molar lobe {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"the ridged or roughened grinding surface of the mandible\"", creation_date="2022-06-20"} def: "The region of the cuticle that is proximal and medial on the cuticle of the insect mandible." [] {creation_date="2022-06-20", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} synonym: "mola" EXACT [] {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\nmola = molar lobe = \"the ridged or roughened grinding surface of the mandible\""} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-20"} ! insect region of cuticle is_a: BSPO:0000078 ! distal region [Term] id: AISM:0004271 name: prostheca {creation_date="2022-06-20", AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"mandibular region set with hair\""} def: "The cuticular lobe of the cuticle of the insect mandible between the mandibular molar lobe and the mandibular incisor lobe." [] {creation_date="2022-06-20", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} synonym: "lacinia mobilis" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"An articulated mesal appendage, the lacinia mobilis or prostheca, occurs in several groups. It can be sclerotized or largely membranous and is often equipped with microtrichia.\""} is_a: AISM:0004237 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-20"} ! cuticular lobe relationship: BFO:0000050 AISM:0000043 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-20"} ! part of insect mandible relationship: BSPO:0000096 AISM:0004270 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-20"} ! anterior to mandibular molar lobe relationship: BSPO:0000099 AISM:0004269 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-20"} ! posterior to mandibular incisor lobe [Term] id: AISM:0004272 name: basistipes {creation_date="2022-06-23", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Basistipes: basolateral part of stipes.\""} def: "The region of cuticle on the lateral region of the cuticle of stipes, adjacent to the distal margin of the cuticle of the cardo, to the proximal margin of the cuticle of the palpifer, and adjacent to the proximal margin of the mediostipes." [] {creation_date="2022-06-23", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-23"} ! insect region of cuticle is_a: BSPO:0000078 ! distal region [Term] id: AISM:0004273 name: mediostipes {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Mediostipes: mesal part of stipes.\""} def: "The region of cuticle on the medial region of the cuticle of stipes, adjacent to the distal margin of the cuticle of the basistipes, and to the proximal margin of the cuticle of the galea and the lacinia." [] {creation_date="2022-06-23", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-23"} ! insect region of cuticle is_a: BSPO:0000078 ! distal region [Term] id: AISM:0004274 name: maxillary gland {AISM:0000171="Snodgrass RE (1993) Principles of Insect Morphology. Cornell University Press, 768 pp.\n\nhttps://www.jstor.org/stable/10.7591/j.ctv1nhm1j\n\n\"Glands present in some insects opening mesally at the bases of the maxillae\""} def: "The ectodermal gland continuous with the proximal region of the cuticle of the cardo." [] {creation_date="2022-06-23", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004235 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-23"} ! ectodermal gland [Term] id: AISM:0004275 name: hypopharyngeal sclerite def: "The sclerite that is continuous with the hypopharynx." [] {creation_date="2022-06-27", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-27"} ! insect sclerite relationship: RO:0002150 AISM:0000093 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-27"} ! continuous with hypopharynx [Term] id: AISM:0004276 name: thoracic foramen {creation_date="2022-06-27"} def: "The arthropod foramen that is part of the cuticle of the insect thorax." [] {creation_date="2022-06-27", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000197 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-27"} ! arthropod foramen relationship: BFO:0000050 AISM:0000108 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-27"} ! part of insect thorax [Term] id: AISM:0004277 name: anterior prothoracic foramen {creation_date="2022-06-27"} def: "The thoracic foramen that is at the anterior margin of the cuticle of the prothorax." [] {creation_date="2022-06-27", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004276 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-27"} ! thoracic foramen [Term] id: AISM:0004278 name: posterior prothoracic foramen {creation_date="2022-06-27"} def: "The thoracic foramen that is at the posterior margin of the cuticle of the prothorax." [] {creation_date="2022-06-27", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004276 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-27"} ! thoracic foramen [Term] id: AISM:0004279 name: anterior mesothoracic foramen {creation_date="2022-06-27"} def: "The thoracic foramen that is at the anterior margin of the cuticle of the mesothorax." [] {creation_date="2022-06-27", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004276 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-27"} ! thoracic foramen [Term] id: AISM:0004280 name: posterior mesothoracic foramen {creation_date="2022-06-27"} def: "The thoracic foramen that is at the posterior margin of the cuticle of the mesothorax." [] {creation_date="2022-06-27", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004276 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-27"} ! thoracic foramen [Term] id: AISM:0004281 name: posterior metathoracic foramen {creation_date="2022-06-27"} def: "The thoracic foramen that is at the posterior margin of the cuticle of the metathorax." [] {creation_date="2022-06-27", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004276 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-27"} ! thoracic foramen [Term] id: AISM:0004282 name: anterior metathoracic foramen {creation_date="2022-06-27"} def: "The thoracic foramen that is at the anterior margin of the cuticle of the metathorax." [] {creation_date="2022-06-27", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004276 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-27"} ! thoracic foramen [Term] id: AISM:0004283 name: insect body segment {creation_date="2023-01-09", AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"segment, subdivision of the body between areas of flexibility associated with muscle attachments\"", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect region of integument that is continuous with conjunctiva and attached to somatic muscle." [] {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} xref: http://flybase.org/cgi-bin/fbcvq.html?query=FBbt\:00000003 "segment" {def="One of the repeated divisions of the whole organism."} xref: http://purl.obolibrary.org/obo/HAO_0000929 "segment" {def="An anatomical structure that is metameric and is connected to other metameric subdivisions by muscles and is delimited by its sclerites."} is_a: UBERON:6007284 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect region of integument relationship: RO:0002150 AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! continuous with conjunctiva relationship: RO:0002371 UBERON:0014895 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! attached to somatic muscle, invertebrate [Term] id: AISM:0004284 name: insect appendage segment {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"segment, subdivision of an appendage between areas of flexibility associated with muscle attachments\""} def: "The insect region of integument that has a ring sclerirte, continuous with ring conjunctiva, and attached to somatic muscle." [] {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: UBERON:6007284 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect region of integument relationship: BFO:0000051 AISM:0000062 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! has part ring sclerite relationship: RO:0002150 AISM:0000102 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! continuous with ring conjunctiva relationship: RO:0002371 UBERON:0014895 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! attached to somatic muscle, invertebrate [Term] id: AISM:0004285 name: insect cephalic segment {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect body segment that is part of the insect head." [] {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} xref: https://flybase.org/cgi-bin/cvreport.pl?cvterm=FBbt\:00000006 "head segment" {def="Any segment (FBbt:00000003) that is part of some head (FBbt:00000004)."} is_a: AISM:0004283 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect body segment is_a: PR:000050567 ! protein-containing material entity relationship: BFO:0000051 AISM:0000107 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! has part insect head [Term] id: AISM:0004286 name: insect thoracic segment {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect body segment that is part of the insect thorax." [] {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} xref: http://flybase.org/cgi-bin/cvreport.pl?cvterm=FBbt\:00000016 "thoracic segment" {def="Any segment (FBbt:00000003) that is part of some thorax (FBbt:00000015)."} is_a: AISM:0004283 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect body segment relationship: BFO:0000051 AISM:0000108 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! has part insect thorax [Term] id: AISM:0004287 name: insect abdominal segment {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect body segment that is part of the insect abdomen." [] {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} xref: http://flybase.org/cgi-bin/cvreport.pl?cvterm=FBbt\:00000021 "abdominal segment" {def="Metameric subdivision of the abdomen."} is_a: AISM:0004283 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect body segment relationship: BFO:0000051 AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! has part insect abdomen [Term] id: AISM:0004288 name: insect abdominal segment I {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect body segment that is part of the insect abdomen and is posterior to the insect metathoracic segment." [] {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} xref: http://flybase.org/cgi-bin/cvreport.pl?cvterm=FBbt\:00000022 "abdominal segment 1" {def="Most anterior segment of the abdomen."} is_a: AISM:0004287 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment relationship: BFO:0000051 AISM:0000021 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! has part abdominal tergite I relationship: BFO:0000051 AISM:0004100 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! has part abdominal sternite I relationship: BSPO:0000099 AISM:0004300 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! posterior to insect metathoracic segment [Term] id: AISM:0004289 name: insect abdominal segment II {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect abdominal segment that is posterior to the insect abdominal segment I and composed of abdominal tergite II and abdominal sternite II." [] {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} xref: http://flybase.org/cgi-bin/cvreport.pl?cvterm=FBbt\:00000023 "abdominal segment 2" {def="Second most anterior segment of the abdomen."} is_a: AISM:0004287 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment relationship: BFO:0000051 AISM:0004085 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! has part abdominal tergite II relationship: BFO:0000051 AISM:0004104 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! has part abdominal sternite II relationship: BSPO:0000099 AISM:0004288 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! posterior to insect abdominal segment I [Term] id: AISM:0004290 name: insect abdominal segment III {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect abdominal segment that is posterior to the insect abdominal segment II and composed of abdominal tergite III and abdominal sternite III." [] {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} xref: http://flybase.org/cgi-bin/cvreport.pl?cvterm=FBbt\:00000024 "abdominal segment 3" {def="Third most anterior segment of the abdomen."} is_a: AISM:0004287 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment relationship: BFO:0000051 AISM:0004087 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! has part abdominal tergite III relationship: BFO:0000051 AISM:0004105 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! has part abdominal sternite III relationship: BSPO:0000099 AISM:0004289 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! posterior to insect abdominal segment II [Term] id: AISM:0004291 name: insect abdominal segment IV {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect abdominal segment that is posterior to the insect abdominal segment III and composed of abdominal tergite IV and abdominal sternite IV." [] {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} xref: http://flybase.org/cgi-bin/cvreport.pl?cvterm=FBbt\:00000025 "abdominal segment 4" {def="Fourth most anterior segment of the abdomen."} is_a: AISM:0004287 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment relationship: BFO:0000051 AISM:0004090 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! has part abdominal tergite IV relationship: BFO:0000051 AISM:0004106 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! has part abdominal sternite IV relationship: BSPO:0000099 AISM:0004290 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! posterior to insect abdominal segment III [Term] id: AISM:0004292 name: insect abdominal segment V {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect abdominal segment that is posterior to the insect abdominal segment IV and composed of abdominal tergite V and abdominal sternite V." [] {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} xref: http://flybase.org/cgi-bin/cvreport.pl?cvterm=FBbt\:00000026 "abdominal segment 5" {def="Fifth most anterior segment of the abdomen."} is_a: AISM:0004287 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment relationship: BFO:0000051 AISM:0004091 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! has part abdominal tergite V relationship: BFO:0000051 AISM:0004107 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! has part abdominal sternite V relationship: BSPO:0000099 AISM:0004291 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! posterior to insect abdominal segment IV [Term] id: AISM:0004293 name: insect abdominal segment VI {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect abdominal segment that is posterior to the insect abdominal segment V and composed of abdominal tergite VI and abdominal sternite VI." [] {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} xref: http://flybase.org/cgi-bin/cvreport.pl?cvterm=FBbt\:00000027 "abdominal segment 6" {def="Sixth most anterior segment of the abdomen."} is_a: AISM:0004287 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment relationship: BFO:0000051 AISM:0004093 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! has part abdominal tergite VI relationship: BFO:0000051 AISM:0004108 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! has part abdominal sternite VI relationship: BSPO:0000099 AISM:0004292 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! posterior to insect abdominal segment V [Term] id: AISM:0004294 name: insect abdominal segment VII {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect abdominal segment that is posterior to the insect abdominal segment VI and composed of abdominal tergite VII and abdominal sternite VII." [] {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} xref: http://flybase.org/cgi-bin/cvreport.pl?cvterm=FBbt\:00000028 "abdominal segment 7" {def="Seventh most anterior segment of the abdomen."} is_a: AISM:0004287 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment relationship: BFO:0000051 AISM:0004095 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! has part abdominal tergite VII relationship: BFO:0000051 AISM:0004109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! has part abdominal sternite VII relationship: BSPO:0000099 AISM:0004293 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! posterior to insect abdominal segment VI [Term] id: AISM:0004295 name: insect abdominal segment VIII {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect abdominal segment that is posterior to the insect abdominal segment VII and composed of abdominal tergite VIII and abdominal sternite VIII." [] {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} xref: http://flybase.org/cgi-bin/cvreport.pl?cvterm=FBbt\:00000029 "abdominal segment 8" {def="Eigth most anterior segment of the abdomen."} is_a: AISM:0004287 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment relationship: BFO:0000051 AISM:0004097 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! has part abdominal tergite VIII relationship: BFO:0000051 AISM:0004110 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! has part abdominal sternite VIII relationship: BSPO:0000099 AISM:0004294 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! posterior to insect abdominal segment VII [Term] id: AISM:0004296 name: insect abdominal segment IX {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect abdominal segment that is posterior to the insect abdominal segment VIII and composed of abdominal tergite IX and abdominal sternite IX." [] {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} xref: http://flybase.org/cgi-bin/cvreport.pl?cvterm=FBbt\:00000030 "abdominal segment 9" {def="Ninth most anterior segment of the abdomen."} is_a: AISM:0004287 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment relationship: BFO:0000051 AISM:0004117 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! has part abdominal tergite IX relationship: BFO:0000051 AISM:0004119 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! has part abdominal sternite IX relationship: BSPO:0000099 AISM:0004295 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! posterior to insect abdominal segment VIII [Term] id: AISM:0004297 name: insect abdominal segment X {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect abdominal segment that is posterior to the insect abdominal segment IX and composed of abdominal tergite X and abdominal sternite X." [] {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} xref: http://flybase.org/cgi-bin/cvreport.pl?cvterm=FBbt\:00000031 "abdominal segment 10" {def="Tenth most anterior segment of the abdomen."} is_a: AISM:0004287 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment relationship: BSPO:0000099 AISM:0004296 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! posterior to insect abdominal segment IX [Term] id: AISM:0004298 name: insect prothoracic segment {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect body segment that corresponds to the prothorax and is posterior to the insect cephalic segment." [] {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004286 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect thoracic segment relationship: BSPO:0000099 AISM:0004285 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! posterior to insect cephalic segment [Term] id: AISM:0004299 name: insect mesothoracic segment {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect body segment that corresponds to the mesothorax and is posterior to the insect prothoracic segment." [] {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004286 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect thoracic segment relationship: BSPO:0000099 AISM:0004298 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! posterior to insect prothoracic segment [Term] id: AISM:0004300 name: insect metathoracic segment {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect body segment that corresponds to the metathorax and is posterior to the insect mesothoracic segment." [] {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004286 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect thoracic segment relationship: BSPO:0000099 AISM:0004299 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! posterior to insect mesothoracic segment [Term] id: AISM:0004301 name: gonocoxite {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Coxopodite (=valvifer, gonocoxa, gonocoxite): short basal piece of ovipositor elements of female genital segments VIII and IX.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The bilaterally paired insect sclerite of the postabdomen, attached to either the abdominal tergite VIII or IX." [] {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} synonym: "coxopodite" EXACT [] {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Coxopodite (=valvifer, gonocoxa, gonocoxite): short basal piece of ovipositor elements of female genital segments VIII and IX.\""} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: BFO:0000050 AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of postabdomen relationship: RO:0000053 PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has characteristic bilaterally paired property_value: IAO:0000589 "cuticle of gonocoxite" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004302 name: insect mouth {AISM:0000171="Snodgrass RE (1993) Principles of Insect Morphology. Cornell University Press, 768 pp.\n\nhttps://www.jstor.org/stable/10.7591/j.ctv1nhm1j\n\n\"Mouth. The external opening of the stomodaeum, situated in the ventral wall of the head between the labrum and the hypopharynx.\"", creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The mouth that is surrounded by insect mandibles, labium, and labrum and is anterior to the hypopharynx." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883 2023-03-30", creation_date="2024-01-25"} synonym: "preoral cavity" EXACT [] {creation_date="2023-01-09", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"The preoral cavity is the space enclosed between the labrum and labium and the paired mandibles and maxillae\"", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: UBERON:0000165 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! mouth relationship: BSPO:0000096 AISM:0000093 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! anterior to hypopharynx relationship: RO:0002219 AISM:0000042 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! surrounded by labrum relationship: RO:0002219 AISM:0000043 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! surrounded by insect mandible relationship: RO:0002219 AISM:0000087 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! surrounded by labium [Term] id: AISM:0004303 name: insect gland opening def: "The orifice that is continuous with an ectodermal gland." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883 2023-03-30", creation_date="2024-01-25"} is_a: UBERON:0000161 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! orifice relationship: RO:0002150 AISM:0004235 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! continuous with ectodermal gland [Term] id: AISM:0004304 name: cuticular sensilla {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Sensilla are the basal functional and structural units of cuticular mechanoreceptors and chemoreceptors. They include the cuticular component (e.g., the cuticle of a seta), the sensory neuron (or neurons), the associated sheath cells with the cavities they enclose and the structures they produce\" p. 5.", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} def: "The region of cuticle that is attached to arthropod sensillum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-10-11"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! insect region of cuticle is_a: UBERON:0000061 ! anatomical structure relationship: RO:0002371 UBERON:0002536 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! attached to arthropod sensillum [Term] id: AISM:0004305 name: sensilla ampullacea {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Modified type of cuticular sensilla sunk below the external cuticular surface\"", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} def: "The cuticular sensilla that is dilated." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883 2023-03-30", creation_date="2024-01-25"} xref: http://purl.obolibrary.org/obo/HAO_0001098 "basiconic capitate peg sensillum" {def="Mushroom-shaped sensory structure on the flagellum, particularly the\nclava; sometimes called the sensilla ampullacea."} is_a: AISM:0004304 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! cuticular sensilla relationship: RO:0000053 PATO:0001571 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! has characteristic dilated [Term] id: AISM:0004306 name: stridulatory file {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} def: "The region of the cuticle that bears an anatomical collection composed of cuticular carinae." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! insect region of cuticle relationship: BFO:0000051 UBERON:0034925 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! has part anatomical collection relationship: RO:0002351 AISM:0000501 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! has member cuticular carina [Term] id: AISM:0004307 name: pretarsal seta {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} def: "The cuticular seta that is adjacent to the cuticle of the pretarsus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} is_a: AISM:0000039 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! cuticular seta relationship: RO:0002220 AISM:0000047 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! adjacent to distitarsus [Term] id: AISM:0004308 name: pulvillus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Pulvilli: smooth or hairy paired lateral membranous lobes below the claws\". p. 44.", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticular protrusion that is part of the pretarsus, ventral to the tarsal claws." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-11-19"} is_a: AISM:0000008 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular protrusion relationship: BFO:0000050 AISM:0000047 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! part of distitarsus relationship: BSPO:0000102 AISM:0004260 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! ventral to distitarsal claw relationship: RO:0000053 PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! has characteristic bilaterally paired property_value: IAO:0000589 "cuticle of pulvillus" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004309 name: arolium {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Arolium: the median hollow lobe of the pretarsus. It can be completely membranous or partly sclerotized.\" p. 42.\n\"unpaired, between the claws\" p. 40.", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The medial cuticular protrusion of the distitarsus." [] {IAO:0000232="Modified 2026-02-14: Updated to distitarsus.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} property_value: IAO:0000589 "cuticle of arolium" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004310 name: radial field of the insect wing def: "The region of the insect wing that is posterior to the costal field of the insect wing." [] {creation_date="2023-01-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004242 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-21"} ! insect wing region relationship: BSPO:0000099 AISM:0004248 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-21"} ! posterior to costal field of the insect wing [Term] id: AISM:0004311 name: cubital field of the insect wing def: "The region of the insect wing that is posterior to the medial field of the insect wing." [] {creation_date="2023-01-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004242 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-21"} ! insect wing region relationship: BSPO:0000099 AISM:0004312 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-21"} ! posterior to medial field of the insect wing [Term] id: AISM:0004312 name: medial field of the insect wing def: "The region of the insect wing that is posterior to the radial field of the insect wing." [] {creation_date="2023-01-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004242 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-21"} ! insect wing region relationship: BSPO:0000099 AISM:0004310 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-21"} ! posterior to radial field of the insect wing [Term] id: AISM:0004313 name: tracheal gill {AISM:0000171="http://insecta.bio.spbu.ru/z/antidictionary/tergalii&gills.htm\n\n\"Paraspiracular tracheal gill. Paired abdominal appendage, whose trachea arises either directly from the spiracular trachea of the same abdominal segment, or from the nearest point of tracheae branching\"", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-02-05"} def: "The bilaterally paired cuticular protrusion that contains insect tracheae." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-02-05"} is_a: AISM:0000008 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-02-05"} ! cuticular protrusion relationship: BFO:0000051 AISM:0000091 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-02-05"} ! has part insect trachea relationship: RO:0000053 PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-02-05"} ! has characteristic bilaterally paired [Term] id: AISM:0004314 name: insect thoracic spiracle {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-02-05"} def: "The insect spiracle that is part of the insect thorax." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-02-05"} is_a: AISM:0000135 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-02-05"} ! insect spiracle relationship: BFO:0000050 AISM:0000108 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-02-05"} ! part of insect thorax [Term] id: AISM:0004315 name: insect abdominal insect spiracle {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-02-05"} def: "The insect spiracle that is part of the insect abdomen." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-02-05"} is_a: AISM:0000135 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-02-05"} ! insect spiracle relationship: BFO:0000050 AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-02-05"} ! part of insect abdomen [Term] id: AISM:0004316 name: insect external male genitalia {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-01-12"} def: "The external male genitalia with insect cuticle and composed of phallobase, phallobasal-parameral conjunctiva, paramere (or parameres), paramero-aedeagal conjunctiva, aedeagus, and endophallus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", x_1.1:creator="2024-01-12"} is_a: UBERON:0004053 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-01-12"} ! external male genitalia relationship: BFO:0000051 AISM:0004062 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-01-12"} ! has part aedeagus relationship: BFO:0000051 AISM:0004063 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-01-12"} ! has part endophallus relationship: BFO:0000051 AISM:0004065 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-01-12"} ! has part phallobase relationship: BFO:0000051 AISM:0004200 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-01-12"} ! has part paramero-aedeagal conjunctiva relationship: BFO:0000051 AISM:0004201 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-01-12"} ! has part phallobasal-parameral conjunctiva relationship: RO:0002180 AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-01-12"} ! has component insect region of cuticle [Term] id: AISM:0004317 name: deflexed {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} def: "A quality inhering in a bearer by virtue of the bearer's surface becoming bent or curving downward or backward." [Oxford Languages through Google.] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} is_a: PATO:0001591 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} ! curvature [Term] id: AISM:0004318 name: antenna with 10 antennomeres {creation_date="2024-06-20", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The antenna that has scapus, pedicellus, and flagellomeres 1-8, and does not have flagellomere 9." [] {creation_date="2024-06-20", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000032 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! antenna relationship: BFO:0000051 AISM:0000334 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part flagellomere 2 relationship: BFO:0000051 AISM:0000335 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part flagellomere 3 relationship: BFO:0000051 AISM:0000336 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part flagellomere 4 relationship: BFO:0000051 AISM:0000337 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part flagellomere 5 relationship: BFO:0000051 AISM:0000338 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part flagellomere 6 relationship: BFO:0000051 AISM:0000339 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part flagellomere 7 relationship: BFO:0000051 AISM:0000340 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-06-20"} ! has part flagellomere 8 [Term] id: AISM:0004319 name: antenna with 11 antennomeres {creation_date="2024-06-20", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The antenna that has scapus, pedicellus, and flagellomeres 1-9." [] {creation_date="2024-06-20", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000032 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! antenna relationship: BFO:0000051 AISM:0000334 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part flagellomere 2 relationship: BFO:0000051 AISM:0000335 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part flagellomere 3 relationship: BFO:0000051 AISM:0000336 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part flagellomere 4 relationship: BFO:0000051 AISM:0000337 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part flagellomere 5 relationship: BFO:0000051 AISM:0000338 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part flagellomere 6 relationship: BFO:0000051 AISM:0000339 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! has part flagellomere 7 relationship: BFO:0000051 AISM:0000340 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-06-20"} ! has part flagellomere 8 [Term] id: AISM:0004320 name: empodial seta {creation_date="2024-06-20", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The cuticular seta that is adjacent to the cuticle of the empodium." [] {creation_date="2024-06-20", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000039 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-06-20"} ! cuticular seta relationship: RO:0002220 AISM:0004261 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-06-20"} ! adjacent to empodium [Term] id: AISM:0004321 name: dorsal cranio-mandibular articulation def: "The insect cranio-mandibular articulation between the dorsal region of the insect mandible and the dorso-lateral region of the head capsule." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2026-02-12"} is_a: AISM:0000014 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2026-02-14"} ! insect cranio-mandibular articulation [Term] id: AISM:0004322 name: ventral cranio-mandibular articulation def: "The insect cranio-mandibular articulation between the ventral region of the insect mandible and the latero-ventral region of the head capsule." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2026-02-12"} is_a: AISM:0000014 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2026-02-14"} ! insect cranio-mandibular articulation [Term] id: BFO:0000001 name: entity [Term] id: BFO:0000002 name: continuant def: "An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts." [] is_a: BFO:0000001 ! entity disjoint_from: BFO:0000003 ! occurrent relationship: BFO:0000050 BFO:0000002 {all_only="true"} ! part of continuant [Term] id: BFO:0000003 name: occurrent def: "An entity that has temporal parts and that happens, unfolds or develops through time." [] is_a: BFO:0000001 ! entity relationship: BFO:0000050 BFO:0000003 {all_only="true"} ! part of occurrent property_value: IAO:0000589 "processual entity (BFO)" xsd:string [Term] id: BFO:0000004 name: independent continuant def: "A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything." [] is_a: BFO:0000002 ! continuant disjoint_from: BFO:0000020 ! specifically dependent continuant disjoint_from: BFO:0000031 ! generically dependent continuant relationship: BFO:0000050 BFO:0000004 {all_only="true"} ! part of independent continuant property_value: IAO:0000589 "anatomical entity (BFO)" xsd:string [Term] id: BFO:0000006 name: spatial region is_a: BFO:0000141 ! immaterial entity [Term] id: BFO:0000009 name: two-dimensional spatial region is_a: BFO:0000006 ! spatial region [Term] id: BFO:0000015 name: process def: "An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t." [] is_a: BFO:0000003 ! occurrent [Term] id: BFO:0000016 name: disposition is_a: BFO:0000017 ! realizable entity disjoint_from: BFO:0000023 ! role [Term] id: BFO:0000017 name: realizable entity def: "A specifically dependent continuant that inheres in continuant entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances." [] is_a: BFO:0000020 ! specifically dependent continuant disjoint_from: BFO:0000019 ! quality relationship: BFO:0000050 BFO:0000017 {all_only="true"} ! part of realizable entity [Term] id: BFO:0000019 name: quality is_a: BFO:0000020 ! specifically dependent continuant relationship: BFO:0000050 BFO:0000019 {all_only="true"} ! part of quality [Term] id: BFO:0000020 name: specifically dependent continuant def: "A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same." [] is_a: BFO:0000002 ! continuant disjoint_from: BFO:0000031 ! generically dependent continuant relationship: BFO:0000050 BFO:0000020 {all_only="true"} ! part of specifically dependent continuant [Term] id: BFO:0000023 name: role def: "A realizable entity the manifestation of which brings about some result or end that is not essential to a continuant in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant in some kinds of natural, social or institutional contexts." [] is_a: BFO:0000017 ! realizable entity [Term] id: BFO:0000031 name: generically dependent continuant is_a: BFO:0000002 ! continuant relationship: BFO:0000050 BFO:0000031 {all_only="true"} ! part of generically dependent continuant [Term] id: BFO:0000034 name: function is_a: BFO:0000016 ! disposition [Term] id: BFO:0000040 name: material entity def: "An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time." [] is_a: BFO:0000004 ! independent continuant disjoint_from: BFO:0000141 ! immaterial entity [Term] id: BFO:0000141 name: immaterial entity is_a: BFO:0000004 ! independent continuant [Term] id: BSPO:0000000 name: left side namespace: spatial def: "The side of an organism that is left of the sagittal plane." [BSPO:cjm] synonym: "left" EXACT [] is_a: BSPO:0000054 ! anatomical side relationship: BSPO:0000110 BSPO:0000007 ! left of right side relationship: BSPO:0015007 BSPO:0000017 ! starts axis left-right axis [Term] id: BSPO:0000001 name: upper side namespace: spatial synonym: "upper" EXACT [] is_a: BSPO:0000054 ! anatomical side relationship: BSPO:0015007 BSPO:0000011 ! starts axis upper-lower axis [Term] id: BSPO:0000002 name: lower side namespace: spatial synonym: "lower" EXACT [] is_a: BSPO:0000054 ! anatomical side relationship: BSPO:0015001 BSPO:0000011 ! finishes axis upper-lower axis [Term] id: BSPO:0000005 name: anatomical surface namespace: spatial def: "A 2D surface of an anatomical continuant." [BSPO:cjm] synonym: "surface" EXACT [] xref: FMA:24137 is_a: CARO:0000010 ! anatomical boundary [Term] id: BSPO:0000006 name: anatomical margin namespace: spatial def: "Fiat anatomical region extending a short distance from the boundary of an object inwards." [BSPO:cjm] synonym: "edge" EXACT [] synonym: "margin" EXACT [] is_a: BSPO:0000070 ! anatomical region [Term] id: BSPO:0000007 name: right side namespace: spatial def: "The side of an organism that is right of the sagittal plane." [BSPO:cjm, BSPO:wd] synonym: "right" EXACT [] is_a: BSPO:0000054 ! anatomical side relationship: BSPO:0015001 BSPO:0000017 ! finishes axis left-right axis [Term] id: BSPO:0000010 name: anatomical axis namespace: spatial def: "A straight line through space, intersecting an anatomical entity." [BSPO:cjm] xref: http://upload.wikimedia.org/wikipedia/commons/3/34/Anatomical_Directions_and_Axes.JPG is_a: CARO:0000008 ! anatomical line relationship: BSPO:0015006 CARO:0000000 ! passes through anatomical entity [Term] id: BSPO:0000011 name: upper-lower axis namespace: spatial def: "An anatomical axis determined by gravity." [BSPO:cjm] is_a: BSPO:0000010 ! anatomical axis [Term] id: BSPO:0000013 name: anterior-posterior axis namespace: spatial def: "An axis that extends through an organism from head end to opposite end of body or tail." [BSPO:cjm] synonym: "A-P axis" EXACT [] synonym: "anteroposterior axis" EXACT [] synonym: "AP axis" EXACT [] is_a: BSPO:0000010 ! anatomical axis intersection_of: BSPO:0000010 ! anatomical axis intersection_of: BSPO:0015005 BSPO:0000018 ! orthogonal to transverse plane relationship: BSPO:0000104 BSPO:0000016 ! approximately perpendicular to dorsal-ventral axis relationship: BSPO:0015005 BSPO:0000018 ! orthogonal to transverse plane [Term] id: BSPO:0000015 name: proximal-distal axis namespace: spatial def: "An axis that extends from the point of attachment of a structure (proximal) to the point furthest away from the plane of attachment (distal)." [BSPO:curators, http://en.wikipedia.org/wiki/Anatomical_terms_of_location] synonym: "proximal/distal" EXACT [] synonym: "proximodistal" EXACT [] is_a: BSPO:0000010 ! anatomical axis [Term] id: BSPO:0000016 name: dorsal-ventral axis namespace: spatial def: "An axis that is approximately perpendicular to the anterior-posterior axis and that extends through the horizontal plane of the body." [BSPO:curators] synonym: "D-V axis" EXACT [] synonym: "dorsoventral axis" EXACT [] synonym: "DV axis" EXACT [] is_a: BSPO:0000010 ! anatomical axis intersection_of: BSPO:0000010 ! anatomical axis intersection_of: BSPO:0015005 BSPO:0000019 ! orthogonal to horizontal plane relationship: BSPO:0015005 BSPO:0000019 ! orthogonal to horizontal plane [Term] id: BSPO:0000017 name: left-right axis namespace: spatial def: "An axis that bisects an organism from left to right sides of body, through a sagittal plane." [BSPO:cjm] synonym: "dextro-sinister axis" EXACT [] synonym: "L-R axis" EXACT [] synonym: "left to right axis" EXACT [] synonym: "LR axis" EXACT [] synonym: "R-L axis" EXACT [] synonym: "right to left axis" EXACT [] synonym: "right-left axis" EXACT [] synonym: "RL axis" EXACT [] is_a: BSPO:0000010 ! anatomical axis intersection_of: BSPO:0000010 ! anatomical axis intersection_of: BSPO:0015005 BSPO:0000417 ! orthogonal to sagittal plane relationship: BSPO:0015005 BSPO:0000417 ! orthogonal to sagittal plane [Term] id: BSPO:0000018 name: transverse plane namespace: spatial def: "Anatomical plane that divides body into anterior and posterior parts." [BSPO:mah] synonym: "axial plane" EXACT [] synonym: "axial section" EXACT [] synonym: "transverse section" EXACT [] xref: FMA:12247 is_a: BSPO:0000400 ! anatomical plane [Term] id: BSPO:0000019 name: horizontal plane namespace: spatial def: "Anatomical plane that divides bilateral body into dorsal and ventral parts." [BSPO:mah] synonym: "frontal plane" EXACT [] synonym: "horizontal anatomical plane" EXACT [FMA:52810] synonym: "horizontal section" EXACT [] xref: FMA:52810 is_a: BSPO:0000400 ! anatomical plane [Term] id: BSPO:0000026 name: antero-dorsal region namespace: spatial def: "Anatomical region that overlaps the anterior and dorsal regions of a body or body part." [BSPO:wd] synonym: "anterodorsal region " EXACT [] is_a: BSPO:0000071 ! anterior region is_a: BSPO:0000079 ! dorsal region intersection_of: BSPO:0000070 ! anatomical region intersection_of: RO:0002131 BSPO:0000055 ! overlaps anterior side intersection_of: RO:0002131 BSPO:0000063 ! overlaps dorsal side creation_date: 2009-06-15T01:01:38Z [Term] id: BSPO:0000027 name: antero-ventral region namespace: spatial def: "Anatomical region that overlaps the anterior and ventral regions of a body or body part." [BSPO:wd] synonym: "anteroventral region " EXACT [] is_a: BSPO:0000071 ! anterior region is_a: BSPO:0000084 ! ventral region intersection_of: BSPO:0000070 ! anatomical region intersection_of: RO:0002131 BSPO:0000055 ! overlaps anterior side intersection_of: RO:0002131 BSPO:0000068 ! overlaps ventral side creation_date: 2009-06-15T01:04:59Z [Term] id: BSPO:0000028 name: postero-lateral region namespace: spatial def: "Anatomical region that overlaps the posterior and lateral regions of the body or body part." [BSPO:wd] synonym: "posterolateral region" EXACT [] is_a: BSPO:0000072 ! posterior region is_a: BSPO:0000082 ! lateral region intersection_of: BSPO:0000070 ! anatomical region intersection_of: RO:0002131 BSPO:0000056 ! overlaps posterior side intersection_of: RO:0002131 BSPO:0000066 ! overlaps lateral side creation_date: 2009-06-15T01:06:01Z [Term] id: BSPO:0000029 name: antero-lateral region namespace: spatial def: "Anatomical region that overlaps the anterior and lateral regions of a body or body part." [BSPO:wd] synonym: "anterolateral region" EXACT [] is_a: BSPO:0000071 ! anterior region is_a: BSPO:0000082 ! lateral region intersection_of: BSPO:0000070 ! anatomical region intersection_of: RO:0002131 BSPO:0000055 ! overlaps anterior side intersection_of: RO:0002131 BSPO:0000066 ! overlaps lateral side creation_date: 2009-06-15T01:07:18Z [Term] id: BSPO:0000030 name: postero-dorsal region namespace: spatial def: "Anatomical region that overlaps the posterior and dorsal regions of the body or body part." [BSPO:wd] synonym: "posterodorsal region" EXACT [] is_a: BSPO:0000072 ! posterior region is_a: BSPO:0000079 ! dorsal region intersection_of: BSPO:0000070 ! anatomical region intersection_of: RO:0002131 BSPO:0000056 ! overlaps posterior side intersection_of: RO:0002131 BSPO:0000063 ! overlaps dorsal side creation_date: 2009-06-15T01:08:13Z [Term] id: BSPO:0000031 name: upper region namespace: spatial is_a: BSPO:0000070 ! anatomical region intersection_of: BSPO:0000070 ! anatomical region intersection_of: RO:0002131 BSPO:0000001 ! overlaps upper side relationship: RO:0002131 BSPO:0000001 ! overlaps upper side [Term] id: BSPO:0000032 name: lower region namespace: spatial is_a: BSPO:0000070 ! anatomical region intersection_of: BSPO:0000070 ! anatomical region intersection_of: RO:0002131 BSPO:0000002 ! overlaps lower side relationship: RO:0002131 BSPO:0000002 ! overlaps lower side [Term] id: BSPO:0000035 name: postero-ventral region namespace: spatial def: "Anatomical region that overlaps the posterior and ventral regions of a body or body part." [BSPO:wd] synonym: "posteroventral region" EXACT [] is_a: BSPO:0000072 ! posterior region is_a: BSPO:0000084 ! ventral region intersection_of: BSPO:0000070 ! anatomical region intersection_of: RO:0002131 BSPO:0000056 ! overlaps posterior side intersection_of: RO:0002131 BSPO:0000068 ! overlaps ventral side creation_date: 2009-06-15T01:08:38Z [Term] id: BSPO:0000042 name: antero-medial margin namespace: spatial def: "Anatomical margin that is located on the antero-medial region of the body or body part." [BSPO:wd] synonym: "anteromedial margin" EXACT [] is_a: BSPO:0000050 ! antero-medial region is_a: BSPO:0000671 ! anterior margin is_a: BSPO:0000683 ! medial margin intersection_of: BSPO:0000006 ! anatomical margin intersection_of: RO:0002131 BSPO:0000055 ! overlaps anterior side intersection_of: RO:0002131 BSPO:0000067 ! overlaps medial side creation_date: 2009-09-10T08:49:57Z [Term] id: BSPO:0000045 name: antero-lateral margin namespace: spatial def: "Anatomical margin that is located on the antero-lateral region of the body or body part." [BSPO:wd] synonym: "anterolateral margin" EXACT [] is_a: BSPO:0000029 ! antero-lateral region is_a: BSPO:0000671 ! anterior margin is_a: BSPO:0000682 ! lateral margin intersection_of: BSPO:0000006 ! anatomical margin intersection_of: RO:0002131 BSPO:0000055 ! overlaps anterior side intersection_of: RO:0002131 BSPO:0000066 ! overlaps lateral side creation_date: 2009-09-10T08:50:37Z [Term] id: BSPO:0000046 name: postero-medial margin namespace: spatial def: "Anatomical margin that is located on the postero-medial region of the body or body part." [BSPO:wd] synonym: "posteromedial margin" EXACT [] is_a: BSPO:0000064 ! postero-medial region is_a: BSPO:0000672 ! posterior margin is_a: BSPO:0000683 ! medial margin intersection_of: BSPO:0000006 ! anatomical margin intersection_of: RO:0002131 BSPO:0000056 ! overlaps posterior side intersection_of: RO:0002131 BSPO:0000067 ! overlaps medial side creation_date: 2009-09-10T08:51:07Z [Term] id: BSPO:0000047 name: postero-lateral margin namespace: spatial def: "Anatomical margin that is located on the postero-lateral region of the body or body part." [BSPO:wd] synonym: "posterolateral margin" EXACT [] is_a: BSPO:0000028 ! postero-lateral region is_a: BSPO:0000672 ! posterior margin is_a: BSPO:0000682 ! lateral margin intersection_of: BSPO:0000006 ! anatomical margin intersection_of: RO:0002131 BSPO:0000056 ! overlaps posterior side intersection_of: RO:0002131 BSPO:0000066 ! overlaps lateral side creation_date: 2009-09-10T08:51:42Z [Term] id: BSPO:0000048 name: dorso-medial margin namespace: spatial def: "Anatomical margin that is located on the dorso-medial region of the body or body part." [BSPO:wd] synonym: "dorso-medial margin" EXACT [] is_a: BSPO:0000069 ! dorso-medial region is_a: BSPO:0000679 ! dorsal margin is_a: BSPO:0000683 ! medial margin intersection_of: BSPO:0000006 ! anatomical margin intersection_of: RO:0002131 BSPO:0000063 ! overlaps dorsal side intersection_of: RO:0002131 BSPO:0000067 ! overlaps medial side creation_date: 2009-09-10T08:52:04Z [Term] id: BSPO:0000049 name: ventro-medial margin namespace: spatial def: "Anatomical margin that is located on the ventro-medial region of the body or body part." [BSPO:wd] synonym: "ventromedial margin" EXACT [] is_a: BSPO:0000112 ! ventro-medial region is_a: BSPO:0000683 ! medial margin is_a: BSPO:0000684 ! ventral margin intersection_of: BSPO:0000006 ! anatomical margin intersection_of: RO:0002131 BSPO:0000067 ! overlaps medial side intersection_of: RO:0002131 BSPO:0000068 ! overlaps ventral side creation_date: 2009-09-10T08:52:48Z [Term] id: BSPO:0000050 name: antero-medial region namespace: spatial def: "Anatomical region that overlaps the anterior and medial regions of the body or body part." [BSPO:wd] synonym: "anteromedial region" EXACT [] is_a: BSPO:0000071 ! anterior region is_a: BSPO:0000083 ! medial region intersection_of: BSPO:0000070 ! anatomical region intersection_of: RO:0002131 BSPO:0000055 ! overlaps anterior side intersection_of: RO:0002131 BSPO:0000067 ! overlaps medial side creation_date: 2009-09-10T08:55:32Z [Term] id: BSPO:0000054 name: anatomical side namespace: spatial def: "An anatomical region bounded by a plane perpendicular to an axis through the middle." [BSPO:cjm] xref: FBql:00005841 is_a: BSPO:0000070 ! anatomical region [Term] id: BSPO:0000055 name: anterior side namespace: spatial def: "An anatomical region that is the entire part of an anatomical structure anterior to a transverse plane and bounded on one side by the same transverse plane." [BSPO:RW] synonym: "anterior" EXACT [] synonym: "rostral" EXACT [] xref: FBcv:0000053 xref: FBql:00005848 is_a: BSPO:0000054 ! anatomical side relationship: BSPO:0000096 BSPO:0000056 ! anterior to posterior side relationship: BSPO:0000113 BSPO:0000056 ! opposite to posterior side relationship: BSPO:0015007 BSPO:0000013 ! starts axis anterior-posterior axis [Term] id: BSPO:0000056 name: posterior side namespace: spatial def: "An anatomical region that is the entire part of an anatomical structure posterior to a transverse plane and bounded on one side by the same transverse plane." [BSPO:RW, BSPO:wd] synonym: "posterior" EXACT [] xref: FBcv:0000065 xref: FBql:00005849 is_a: BSPO:0000054 ! anatomical side relationship: BSPO:0000099 BSPO:0000055 ! posterior to anterior side relationship: BSPO:0015001 BSPO:0000013 ! finishes axis anterior-posterior axis [Term] id: BSPO:0000061 name: proximal side namespace: spatial synonym: "proximal" EXACT [] xref: FBcv:0000066 xref: FBql:00005852 is_a: BSPO:0000054 ! anatomical side relationship: BSPO:0000113 BSPO:0000062 ! opposite to distal side relationship: BSPO:0015007 BSPO:0000015 ! starts axis proximal-distal axis [Term] id: BSPO:0000062 name: distal side namespace: spatial def: "Anatomical side that is distally located on an organism or structure." [BSPO:wd] synonym: "distal" EXACT [] xref: FBcv:0000058 xref: FBql:00005853 is_a: BSPO:0000054 ! anatomical side relationship: BSPO:0000097 BSPO:0000061 ! distal to proximal side relationship: BSPO:0015001 BSPO:0000015 ! finishes axis proximal-distal axis [Term] id: BSPO:0000063 name: dorsal side namespace: spatial def: "An anatomical region that is the entire part of an anatomical structure dorsal to a horizontal plane and bounded on one side by the same transverse plane." [BSPO:wd] synonym: "dorsal" EXACT [] xref: FBcv:0000059 xref: FBql:00005842 is_a: BSPO:0000054 ! anatomical side relationship: BSPO:0000098 BSPO:0000066 ! dorsal to lateral side relationship: BSPO:0000113 BSPO:0000068 ! opposite to ventral side relationship: BSPO:0015007 BSPO:0000016 ! starts axis dorsal-ventral axis [Term] id: BSPO:0000064 name: postero-medial region namespace: spatial def: "Anatomical region that overlaps the posterior and medial regions of the body or body part." [BSPO:wd] synonym: "posteromedial region" EXACT [] is_a: BSPO:0000072 ! posterior region is_a: BSPO:0000083 ! medial region intersection_of: BSPO:0000070 ! anatomical region intersection_of: RO:0002131 BSPO:0000056 ! overlaps posterior side intersection_of: RO:0002131 BSPO:0000067 ! overlaps medial side creation_date: 2009-09-10T08:56:39Z [Term] id: BSPO:0000066 name: lateral side namespace: spatial synonym: "lateral" EXACT [] xref: FBcv:0000063 xref: FBql:00005844 is_a: BSPO:0000054 ! anatomical side [Term] id: BSPO:0000067 name: medial side namespace: spatial synonym: "medial" EXACT [] xref: FBcv:0000064 xref: FBql:00005847 is_a: BSPO:0000054 ! anatomical side [Term] id: BSPO:0000068 name: ventral side namespace: spatial def: "An anatomical region that is the entire part of an anatomical structure ventral to a horizontal plane and bounded on one side by the same horizontal plane." [BSPO:RW, BSPO:wd] synonym: "ventral" EXACT [] xref: FBcv:0000070 xref: FBql:00005843 is_a: BSPO:0000054 ! anatomical side relationship: BSPO:0015001 BSPO:0000016 ! finishes axis dorsal-ventral axis [Term] id: BSPO:0000069 name: dorso-medial region namespace: spatial def: "Anatomical region that overlaps the dorsal and medial regions of the body or body part." [BSPO:wd] synonym: "dorsomedial region" EXACT [] is_a: BSPO:0000079 ! dorsal region is_a: BSPO:0000083 ! medial region intersection_of: BSPO:0000070 ! anatomical region intersection_of: RO:0002131 BSPO:0000063 ! overlaps dorsal side intersection_of: RO:0002131 BSPO:0000067 ! overlaps medial side creation_date: 2009-09-10T08:57:22Z [Term] id: BSPO:0000070 name: anatomical region namespace: spatial def: "A 3D region in space without well-defined compartmental boundaries; for example, the dorsal region of an ectoderm." [BSPO:cjm] xref: FBql:00005841 is_a: CARO:0000003 ! anatomical structure [Term] id: BSPO:0000071 name: anterior region namespace: spatial def: "Anatomical region anteriorly located on the body or body part." [BSPO:wd] xref: FBql:00005848 is_a: BSPO:0000070 ! anatomical region intersection_of: BSPO:0000070 ! anatomical region intersection_of: RO:0002131 BSPO:0000055 ! overlaps anterior side relationship: RO:0002131 BSPO:0000055 ! overlaps anterior side [Term] id: BSPO:0000072 name: posterior region namespace: spatial def: "Anatomical region posteriorly located on the body or body part." [BSPO:wd] xref: FBql:00005849 is_a: BSPO:0000070 ! anatomical region intersection_of: BSPO:0000070 ! anatomical region intersection_of: RO:0002131 BSPO:0000056 ! overlaps posterior side relationship: RO:0002131 BSPO:0000056 ! overlaps posterior side [Term] id: BSPO:0000077 name: proximal region namespace: spatial def: "Anatomical region proximally located on the body or body part." [BSPO:wd] xref: FBql:00005852 is_a: BSPO:0000070 ! anatomical region intersection_of: BSPO:0000070 ! anatomical region intersection_of: RO:0002131 BSPO:0000061 ! overlaps proximal side relationship: RO:0002131 BSPO:0000061 ! overlaps proximal side [Term] id: BSPO:0000078 name: distal region namespace: spatial def: "Anatomical region distally located on the body or body part." [BSPO:wd] xref: FBql:00005853 is_a: BSPO:0000070 ! anatomical region intersection_of: BSPO:0000070 ! anatomical region intersection_of: RO:0002131 BSPO:0000062 ! overlaps distal side relationship: RO:0002131 BSPO:0000062 ! overlaps distal side [Term] id: BSPO:0000079 name: dorsal region namespace: spatial def: "Anatomical region dorsally located on the body or body part." [BSPO:wd] xref: FBql:00005842 is_a: BSPO:0000070 ! anatomical region intersection_of: BSPO:0000070 ! anatomical region intersection_of: RO:0002131 BSPO:0000063 ! overlaps dorsal side relationship: RO:0002131 BSPO:0000063 ! overlaps dorsal side [Term] id: BSPO:0000080 name: dorso-lateral region namespace: spatial def: "Anatomical region that overlaps the dorsal and lateral regions of a body or body part." [BSPO:wd] synonym: "dorsolateral region" EXACT [] xref: FBql:00005845 is_a: BSPO:0000079 ! dorsal region is_a: BSPO:0000082 ! lateral region intersection_of: BSPO:0000070 ! anatomical region intersection_of: RO:0002131 BSPO:0000063 ! overlaps dorsal side intersection_of: RO:0002131 BSPO:0000066 ! overlaps lateral side [Term] id: BSPO:0000082 name: lateral region namespace: spatial def: "Anatomical region laterally located on the body or body part." [BSPO:wd] xref: FBql:00005844 is_a: BSPO:0000070 ! anatomical region intersection_of: BSPO:0000070 ! anatomical region intersection_of: RO:0002131 BSPO:0000066 ! overlaps lateral side relationship: RO:0002131 BSPO:0000066 ! overlaps lateral side [Term] id: BSPO:0000083 name: medial region namespace: spatial def: "Anatomical region medially located on the body or body part." [BSPO:wd] xref: FBql:00005847 is_a: BSPO:0000070 ! anatomical region intersection_of: BSPO:0000070 ! anatomical region intersection_of: RO:0002131 BSPO:0000067 ! overlaps medial side relationship: RO:0002131 BSPO:0000067 ! overlaps medial side [Term] id: BSPO:0000084 name: ventral region namespace: spatial def: "Anatomical region ventrally located on the body or body part." [BSPO:wd] xref: FBql:00005843 is_a: BSPO:0000070 ! anatomical region intersection_of: BSPO:0000070 ! anatomical region intersection_of: RO:0002131 BSPO:0000068 ! overlaps ventral side relationship: RO:0002131 BSPO:0000068 ! overlaps ventral side [Term] id: BSPO:0000085 name: ventro-lateral region namespace: spatial def: "Anatomical region that overlaps the ventral and lateral regions of a body or body part." [BSPO:wd] synonym: "ventrolateral region" EXACT [] xref: FBql:00005846 is_a: BSPO:0000082 ! lateral region is_a: BSPO:0000084 ! ventral region intersection_of: BSPO:0000070 ! anatomical region intersection_of: RO:0002131 BSPO:0000066 ! overlaps lateral side intersection_of: RO:0002131 BSPO:0000068 ! overlaps ventral side [Term] id: BSPO:0000112 name: ventro-medial region namespace: spatial def: "The region corresponding to the ventral region of the entity, towards the midline." [BSPO:wd] synonym: "medioventral region" EXACT [] synonym: "ventromedial region" EXACT [] is_a: BSPO:0000083 ! medial region is_a: BSPO:0000084 ! ventral region intersection_of: BSPO:0000070 ! anatomical region intersection_of: RO:0002131 BSPO:0000067 ! overlaps medial side intersection_of: RO:0002131 BSPO:0000068 ! overlaps ventral side creation_date: 2009-09-10T08:57:54Z [Term] id: BSPO:0000371 name: anterior surface namespace: spatial def: "Anatomical surface that is located on the anterior side of the body or body part." [BSPO:wd] xref: FBql:00005848 is_a: BSPO:0000005 ! anatomical surface intersection_of: BSPO:0000005 ! anatomical surface intersection_of: BSPO:0015008 BSPO:0000055 ! surface of anterior side relationship: BSPO:0015008 BSPO:0000055 ! surface of anterior side [Term] id: BSPO:0000372 name: posterior surface namespace: spatial def: "Anatomical surface that is located on the posterior side of the body or body part." [BSPO:wd] xref: FBql:00005849 is_a: BSPO:0000005 ! anatomical surface intersection_of: BSPO:0000005 ! anatomical surface intersection_of: BSPO:0015008 BSPO:0000056 ! surface of posterior side relationship: BSPO:0015008 BSPO:0000056 ! surface of posterior side [Term] id: BSPO:0000377 name: proximal surface namespace: spatial def: "Anatomical surface that is located on the proximal side of the body or body part." [BSPO:wd] xref: FBql:00005852 is_a: BSPO:0000005 ! anatomical surface intersection_of: BSPO:0000005 ! anatomical surface intersection_of: BSPO:0015008 BSPO:0000061 ! surface of proximal side relationship: BSPO:0000113 BSPO:0000378 ! opposite to distal surface relationship: BSPO:0015008 BSPO:0000061 ! surface of proximal side [Term] id: BSPO:0000378 name: distal surface namespace: spatial def: "Anatomical surface that is located on the distal side of the body or body part." [BSPO:wd] xref: FBql:00005853 is_a: BSPO:0000005 ! anatomical surface intersection_of: BSPO:0000005 ! anatomical surface intersection_of: BSPO:0015008 BSPO:0000062 ! surface of distal side relationship: BSPO:0000113 BSPO:0000377 ! opposite to proximal surface relationship: BSPO:0015008 BSPO:0000062 ! surface of distal side [Term] id: BSPO:0000379 name: dorsal surface namespace: spatial def: "Anatomical surface that located on the dorsal side of the body or body part." [BSPO:wd] xref: FBql:00005842 is_a: BSPO:0000005 ! anatomical surface intersection_of: BSPO:0000005 ! anatomical surface intersection_of: BSPO:0015008 BSPO:0000063 ! surface of dorsal side relationship: BSPO:0015008 BSPO:0000063 ! surface of dorsal side [Term] id: BSPO:0000382 name: lateral surface namespace: spatial def: "Anatomical surface that located on the lateral side of the body or body part." [BSPO:wd] xref: FBql:00005844 is_a: BSPO:0000005 ! anatomical surface intersection_of: BSPO:0000005 ! anatomical surface intersection_of: BSPO:0015008 BSPO:0000066 ! surface of lateral side relationship: BSPO:0015008 BSPO:0000066 ! surface of lateral side [Term] id: BSPO:0000383 name: medial surface namespace: spatial def: "Anatomical surface that located on the medial side of the body or body part." [BSPO:wd] xref: FBql:00005847 is_a: BSPO:0000005 ! anatomical surface intersection_of: BSPO:0000005 ! anatomical surface intersection_of: BSPO:0015008 BSPO:0000067 ! surface of medial side relationship: BSPO:0015008 BSPO:0000067 ! surface of medial side [Term] id: BSPO:0000384 name: ventral surface namespace: spatial def: "Anatomical surface that is located on the ventral side of the body or body part." [BSPO:wd] xref: FBql:00005843 is_a: BSPO:0000005 ! anatomical surface intersection_of: BSPO:0000005 ! anatomical surface intersection_of: BSPO:0015008 BSPO:0000068 ! surface of ventral side relationship: BSPO:0015008 BSPO:0000068 ! surface of ventral side [Term] id: BSPO:0000400 name: anatomical plane namespace: spatial def: "A flat 2D plane intersecting an anatomical continuant, dividing it into two adjacent portions." [BSPO:cjm] synonym: "anatomical cross-section" EXACT [] synonym: "anatomical section" EXACT [] synonym: "plane" EXACT [] synonym: "section" EXACT [] xref: FMA:242982 is_a: CARO:0000010 ! anatomical boundary [Term] id: BSPO:0000417 name: sagittal plane namespace: spatial def: "Anatomical plane that divides a bilateral body into left and right parts, not necessarily of even size." [BSPO:cjm, BSPO:DOS, BSPO:mah] synonym: "left/right plane" EXACT [] synonym: "median plane" EXACT [] synonym: "sagittal section" EXACT [] xref: FMA:11361 is_a: BSPO:0000010 ! anatomical axis is_a: BSPO:0000400 ! anatomical plane intersection_of: BSPO:0000400 ! anatomical plane intersection_of: BSPO:0001102 BSPO:0000013 ! parallel to anterior-posterior axis intersection_of: BSPO:0001102 BSPO:0000016 ! parallel to dorsal-ventral axis intersection_of: BSPO:0015005 BSPO:0000017 ! orthogonal to left-right axis relationship: BSPO:0001102 BSPO:0000013 ! parallel to anterior-posterior axis relationship: BSPO:0001102 BSPO:0000016 ! parallel to dorsal-ventral axis relationship: BSPO:0015005 BSPO:0000017 ! orthogonal to left-right axis [Term] id: BSPO:0000671 name: anterior margin namespace: spatial def: "Anatomical margin that is located on the anterior side of a body or body part." [BSPO:wd] is_a: BSPO:0000006 ! anatomical margin is_a: BSPO:0000071 ! anterior region intersection_of: BSPO:0000006 ! anatomical margin intersection_of: RO:0002131 BSPO:0000055 ! overlaps anterior side [Term] id: BSPO:0000672 name: posterior margin namespace: spatial def: "Anatomical margin that is located on the posterior side of the body or body part." [BSPO:wd] is_a: BSPO:0000006 ! anatomical margin is_a: BSPO:0000072 ! posterior region intersection_of: BSPO:0000006 ! anatomical margin intersection_of: RO:0002131 BSPO:0000056 ! overlaps posterior side [Term] id: BSPO:0000677 name: proximal margin namespace: spatial def: "Anatomical margin that is located on the proximal region of the body or body part." [BSPO:wd] is_a: BSPO:0000006 ! anatomical margin is_a: BSPO:0000077 ! proximal region intersection_of: BSPO:0000006 ! anatomical margin intersection_of: RO:0002131 BSPO:0000061 ! overlaps proximal side [Term] id: BSPO:0000678 name: distal margin namespace: spatial def: "Anatomical margin that is located on the distal side of the body or body part." [BSPO:wd] is_a: BSPO:0000006 ! anatomical margin is_a: BSPO:0000078 ! distal region intersection_of: BSPO:0000006 ! anatomical margin intersection_of: RO:0002131 BSPO:0000062 ! overlaps distal side [Term] id: BSPO:0000679 name: dorsal margin namespace: spatial def: "Anatomical margin that is located on the dorsal side of body or body part." [BSPO:wd] is_a: BSPO:0000006 ! anatomical margin is_a: BSPO:0000079 ! dorsal region intersection_of: BSPO:0000006 ! anatomical margin intersection_of: RO:0002131 BSPO:0000063 ! overlaps dorsal side [Term] id: BSPO:0000680 name: dorso-lateral margin namespace: spatial def: "Anatomical margin that is located on the dorso-lateral region of the body or body part." [BSPO:wd] synonym: "dorsolateral margin" EXACT [] is_a: BSPO:0000080 ! dorso-lateral region is_a: BSPO:0000679 ! dorsal margin is_a: BSPO:0000682 ! lateral margin intersection_of: BSPO:0000006 ! anatomical margin intersection_of: RO:0002131 BSPO:0000063 ! overlaps dorsal side intersection_of: RO:0002131 BSPO:0000066 ! overlaps lateral side [Term] id: BSPO:0000682 name: lateral margin namespace: spatial def: "Anatomical margin that is located on the lateral side of the body or body part." [BSPO:wd] is_a: BSPO:0000006 ! anatomical margin is_a: BSPO:0000082 ! lateral region intersection_of: BSPO:0000006 ! anatomical margin intersection_of: RO:0002131 BSPO:0000066 ! overlaps lateral side [Term] id: BSPO:0000683 name: medial margin namespace: spatial def: "Anatomical margin that is located on the medial side of the body or body part." [BSPO:wd] is_a: BSPO:0000006 ! anatomical margin is_a: BSPO:0000083 ! medial region intersection_of: BSPO:0000006 ! anatomical margin intersection_of: RO:0002131 BSPO:0000067 ! overlaps medial side [Term] id: BSPO:0000684 name: ventral margin namespace: spatial def: "Anatomical margin that is located on the ventral side of the body or body part." [BSPO:wd] is_a: BSPO:0000006 ! anatomical margin is_a: BSPO:0000084 ! ventral region intersection_of: BSPO:0000006 ! anatomical margin intersection_of: RO:0002131 BSPO:0000068 ! overlaps ventral side [Term] id: BSPO:0000685 name: ventro-lateral margin namespace: spatial def: "Anatomical margin that is located on the ventro-lateral region of the body or body part." [BSPO:wd] synonym: "ventrolateral margin" EXACT [] is_a: BSPO:0000085 ! ventro-lateral region is_a: BSPO:0000682 ! lateral margin is_a: BSPO:0000684 ! ventral margin intersection_of: BSPO:0000006 ! anatomical margin intersection_of: RO:0002131 BSPO:0000066 ! overlaps lateral side intersection_of: RO:0002131 BSPO:0000068 ! overlaps ventral side [Term] id: BSPO:0000686 name: antero-dorsal margin namespace: spatial def: "Anatomical margin that is located on the antero-dorso region of the body or body part." [BSPO:wd] synonym: "anterodorsal margin" EXACT [] is_a: BSPO:0000026 ! antero-dorsal region is_a: BSPO:0000671 ! anterior margin is_a: BSPO:0000679 ! dorsal margin intersection_of: BSPO:0000006 ! anatomical margin intersection_of: RO:0002131 BSPO:0000055 ! overlaps anterior side intersection_of: RO:0002131 BSPO:0000063 ! overlaps dorsal side [Term] id: BSPO:0000687 name: postero-dorsal margin namespace: spatial def: "Anatomical margin that is located on the postero-dorsal region of the body or body part." [BSPO:wd] synonym: "posterodorsal margin" EXACT [] is_a: BSPO:0000030 ! postero-dorsal region is_a: BSPO:0000672 ! posterior margin is_a: BSPO:0000679 ! dorsal margin intersection_of: BSPO:0000006 ! anatomical margin intersection_of: RO:0002131 BSPO:0000056 ! overlaps posterior side intersection_of: RO:0002131 BSPO:0000063 ! overlaps dorsal side [Term] id: BSPO:0000688 name: antero-ventral margin namespace: spatial def: "Anatomical margin that is located on the antero-ventral region of the body or body part." [BSPO:wd] synonym: "anteroventral margin" EXACT [] is_a: BSPO:0000027 ! antero-ventral region is_a: BSPO:0000671 ! anterior margin is_a: BSPO:0000684 ! ventral margin intersection_of: BSPO:0000006 ! anatomical margin intersection_of: RO:0002131 BSPO:0000055 ! overlaps anterior side intersection_of: RO:0002131 BSPO:0000068 ! overlaps ventral side [Term] id: BSPO:0000689 name: postero-ventral margin namespace: spatial def: "Anatomical margin that is located on the postero-ventral region of the body or body part." [BSPO:wd] synonym: "posteroventral margin" EXACT [] is_a: BSPO:0000035 ! postero-ventral region is_a: BSPO:0000672 ! posterior margin is_a: BSPO:0000684 ! ventral margin intersection_of: BSPO:0000006 ! anatomical margin intersection_of: RO:0002131 BSPO:0000056 ! overlaps posterior side intersection_of: RO:0002131 BSPO:0000068 ! overlaps ventral side [Term] id: CARO:0000000 name: anatomical entity namespace: spatial def: "A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex. Or, a substance produced by a cellular organism with granularity above the level of a protein complex." [CAROC:Brownsville2014] is_a: BFO:0000004 ! independent continuant [Term] id: CARO:0000003 name: anatomical structure namespace: spatial def: "Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome." [CC:DOS] is_a: CARO:0000006 ! material anatomical entity [Term] id: CARO:0000006 name: material anatomical entity namespace: spatial def: "An anatomical entity that has mass." [CC:DOS] is_a: CARO:0000000 ! anatomical entity disjoint_from: CARO:0000007 ! immaterial anatomical entity [Term] id: CARO:0000007 name: immaterial anatomical entity namespace: spatial def: "An anatomical entity that has no mass." [CC:DOS] is_a: BFO:0000141 ! immaterial entity is_a: CARO:0000000 ! anatomical entity [Term] id: CARO:0000008 name: anatomical line namespace: spatial def: "A one dimensional, immaterial anatomical entity." [CC:DOS] is_a: CARO:0000007 ! immaterial anatomical entity [Term] id: CARO:0000010 name: anatomical boundary namespace: spatial def: "A non-material anatomical entity of two dimensions. Anatomical boundaries are contiguous structures." [CC:DOS] is_a: CARO:0000007 ! immaterial anatomical entity [Term] id: CHEBI:10545 name: electron namespace: chebi_ontology def: "Elementary particle not affected by the strong force having a spin 1/2, a negative elementary charge and a rest mass of 0.000548579903(13) u, or 0.51099906(15) MeV." [] synonym: "electron" EXACT [ChEBI, KEGG_COMPOUND] xref: KEGG:C05359 xref: PMID:21614077 {source="Europe PMC"} xref: Wikipedia:Electron is_a: CHEBI:36338 ! lepton [Term] id: CHEBI:131927 name: dicarboxylic acids and O-substituted derivatives namespace: chebi_ontology def: "A class of carbonyl compound encompassing dicarboxylic acids and any derivatives obtained by substitution of either one or both of the carboxy hydrogens." [] is_a: CHEBI:36586 ! carbonyl compound [Term] id: CHEBI:132153 name: hyaluronate namespace: chebi_ontology def: "A carbohydrate acid derivative anion obtained by deprotonation of the carboxy groups of hyaluronic acid; major species at pH 7.3." [] is_a: CHEBI:61469 ! polyanionic polymer is_a: CHEBI:63551 ! carbohydrate acid derivative anion relationship: is_conjugate_base_of CHEBI:16336 ! hyaluronic acid [Term] id: CHEBI:136889 name: 5beta steroid namespace: chebi_ontology def: "Any steroid that has beta-configuration at position 5." [] is_a: CHEBI:35341 ! steroid [Term] id: CHEBI:138103 name: inorganic acid namespace: chebi_ontology def: "A Bronsted acid derived from one or more inorganic compounds. Inorganic acids (also known as mineral acids) form hydrons and conjugate base ions when dissolved in water." [] xref: Wikipedia:Mineral_acid is_a: CHEBI:39141 ! Bronsted acid [Term] id: CHEBI:138366 name: bile acids namespace: chebi_ontology def: "Any member of a group of hydroxy steroids occuring in bile, where they are present as the sodium salts of their amides with glycine or taurine. In mammals bile acids almost invariably have 5beta-configuration, while in lower vertebrates, some bile acids, known as allo-bile acids, have 5alpha-configuration." [] is_a: CHEBI:25384 ! monocarboxylic acid is_a: CHEBI:35350 ! hydroxy steroid is_a: CHEBI:36078 ! cholanoid [Term] id: CHEBI:138675 name: gas molecular entity namespace: chebi_ontology def: "Any main group molecular entity that is gaseous at standard temperature and pressure (STP; 0degreeC and 100 kPa)." [] xref: Wikipedia:https\://en.wikipedia.org/wiki/Gas is_a: CHEBI:33579 ! main group molecular entity [Term] id: CHEBI:13941 name: carbamate namespace: chebi_ontology synonym: "carbamate" EXACT [UniProt] xref: Beilstein:3903503 {source="Beilstein"} xref: CAS:302-11-4 {source="ChemIDplus"} xref: Gmelin:239604 {source="Gmelin"} is_a: CHEBI:37022 ! amino-acid anion relationship: is_conjugate_base_of CHEBI:28616 ! carbamic acid [Term] id: CHEBI:142163 name: 24G7 epitope namespace: chebi_ontology def: "An antigenic epitope recognized by an anti-bilirubin monoclonal antibody designated 24G7. A substructure of bilirubin IXalpha, it is the region containing the oxo group at C-1, the methyl group at C-2, C-(4, 5, 6, 9), and N-21 and -22." [] is_a: BFO:0000004 ! independent continuant is_a: CHEBI:24433 ! group relationship: RO:0000087 CHEBI:53000 ! has role epitope [Term] id: CHEBI:15339 name: acceptor namespace: chebi_ontology def: "A molecular entity that can accept an electron, a pair of electrons, an atom or a group from another molecular entity." [] synonym: "Acceptor" EXACT [KEGG_COMPOUND] xref: KEGG:C00028 xref: KEGG:C16722 is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:15355 name: acetylcholine namespace: chebi_ontology def: "Actylcholine is an ester of acetic acid and choline, which acts as a neurotransmitter." [] synonym: "ACETYLCHOLINE" EXACT [PDBeChem] synonym: "Acetylcholine" EXACT [KEGG_COMPOUND] synonym: "acetylcholine" EXACT [UniProt] xref: Beilstein:1764436 {source="ChemIDplus"} xref: CAS:51-84-3 {source="ChemIDplus", source="KEGG COMPOUND"} xref: Drug_Central:65 {source="DrugCentral"} xref: DrugBank:DB03128 xref: Gmelin:326108 {source="Gmelin"} xref: KEGG:C01996 xref: LINCS:LSM-5888 xref: PDBeChem:ACH xref: PMID:14764638 {source="Europe PMC"} xref: PMID:15014918 {source="Europe PMC"} xref: PMID:15231705 {source="Europe PMC"} xref: PMID:15361288 {source="Europe PMC"} xref: PMID:18050502 {source="Europe PMC"} xref: PMID:18407448 {source="Europe PMC"} xref: PMID:19255787 {source="Europe PMC"} xref: PMID:20963497 {source="Europe PMC"} xref: PMID:21130809 {source="Europe PMC"} xref: PMID:21246223 {source="Europe PMC"} xref: PMID:21545631 {source="Europe PMC"} xref: PMID:21601579 {source="Europe PMC"} xref: Wikipedia:Acetylcholine is_a: BFO:0000004 ! independent continuant is_a: CHEBI:35287 ! acylcholine is_a: CHEBI:47622 ! acetate ester relationship: RO:0000087 CHEBI:24621 ! has role hormone relationship: RO:0000087 CHEBI:25512 ! has role neurotransmitter relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent relationship: RO:0000087 CHEBI:38325 ! has role muscarinic agonist relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite relationship: RO:0000087 CHEBI:77746 ! has role human metabolite [Term] id: CHEBI:15366 name: acetic acid namespace: chebi_ontology def: "A simple monocarboxylic acid containing two carbons." [] synonym: "ACETIC ACID" EXACT [PDBeChem] synonym: "Acetic acid" EXACT [KEGG_COMPOUND] xref: Beilstein:506007 {source="Beilstein"} xref: CAS:64-19-7 {source="ChemIDplus", source="KEGG COMPOUND", source="NIST Chemistry WebBook"} xref: Drug_Central:4211 {source="DrugCentral"} xref: Gmelin:1380 {source="Gmelin"} xref: HMDB:HMDB0000042 xref: KEGG:C00033 xref: KEGG:D00010 xref: KNApSAcK:C00001176 xref: LIPID_MAPS_instance:LMFA01010002 {source="LIPID MAPS"} xref: MetaCyc:ACET xref: PDBeChem:ACT xref: PDBeChem:ACY xref: PMID:12005138 {source="Europe PMC"} xref: PMID:15107950 {source="Europe PMC"} xref: PMID:16630552 {source="Europe PMC"} xref: PMID:16774200 {source="Europe PMC"} xref: PMID:17190852 {source="Europe PMC"} xref: PMID:19416101 {source="Europe PMC"} xref: PMID:19469536 {source="Europe PMC"} xref: PMID:22153255 {source="Europe PMC"} xref: PMID:22173419 {source="Europe PMC"} xref: PPDB:1333 xref: Reaxys:506007 {source="Reaxys"} xref: Wikipedia:Acetic_acid is_a: CHEBI:25384 ! monocarboxylic acid relationship: is_conjugate_acid_of CHEBI:30089 ! acetate relationship: RO:0000087 CHEBI:48356 ! has role protic solvent relationship: RO:0000087 CHEBI:64049 ! has role food acidity regulator relationship: RO:0000087 CHEBI:65256 ! has role antimicrobial food preservative relationship: RO:0000087 CHEBI:83056 ! has role Daphnia magna metabolite [Term] id: CHEBI:15379 name: dioxygen namespace: chebi_ontology xref: CAS:7782-44-7 {source="ChemIDplus", source="KEGG COMPOUND", source="NIST Chemistry WebBook"} xref: Gmelin:485 {source="Gmelin"} xref: HMDB:HMDB0001377 xref: KEGG:C00007 xref: KEGG:D00003 xref: MetaCyc:OXYGEN-MOLECULE xref: MolBase:750 xref: PDBeChem:OXY xref: PMID:10906528 {source="Europe PMC"} xref: PMID:16977326 {source="Europe PMC"} xref: PMID:18210929 {source="Europe PMC"} xref: PMID:18638417 {source="Europe PMC"} xref: PMID:19840863 {source="Europe PMC"} xref: PMID:7710549 {source="Europe PMC"} xref: PMID:9463773 {source="Europe PMC"} xref: Wikipedia:Oxygen is_a: BFO:0000004 ! independent continuant is_a: CHEBI:138675 ! gas molecular entity is_a: CHEBI:25362 ! elemental molecule is_a: CHEBI:33263 ! diatomic oxygen relationship: is_conjugate_base_of CHEBI:29793 ! hydridodioxygen(1+) relationship: RO:0000087 CHEBI:27027 ! has role micronutrient relationship: RO:0000087 CHEBI:33893 ! has role reagent relationship: RO:0000087 CHEBI:35472 ! has role anti-inflammatory drug relationship: RO:0000087 CHEBI:63248 ! has role oxidising agent relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite relationship: RO:0000087 CHEBI:77746 ! has role human metabolite relationship: RO:0000087 CHEBI:77974 ! has role food packaging gas [Term] id: CHEBI:15693 name: aldose namespace: chebi_ontology def: "Aldehydic parent sugars (polyhydroxy aldehydes H[CH(OH)]nC(=O)H, n >= 2) and their intramolecular hemiacetals." [] synonym: "Aldose" EXACT [KEGG_COMPOUND] xref: KEGG:C01370 xref: Wikipedia:Aldose is_a: CHEBI:35381 ! monosaccharide [Term] id: CHEBI:15841 name: polypeptide namespace: chebi_ontology def: "A peptide containing ten or more amino acid residues." [] synonym: "Polypeptide" EXACT [KEGG_COMPOUND] xref: KEGG:C00403 is_a: CHEBI:16670 ! peptide is_a: CHEBI:33839 ! macromolecule [Term] id: CHEBI:15986 name: polynucleotide namespace: chebi_ontology def: "A nucleobase-containing molecular entity with a polymeric structure comprised of a linear sequence of 13 or more nucleotide residues." [] synonym: "Polynucleotide" EXACT [KEGG_COMPOUND] xref: KEGG:C00419 is_a: CHEBI:33695 ! information biomacromolecule is_a: CHEBI:61120 ! nucleobase-containing molecular entity relationship: BFO:0000051 CHEBI:50319 ! has part nucleotide residue [Term] id: CHEBI:16134 name: ammonia namespace: chebi_ontology def: "An azane that consists of a single nitrogen atom covelently bonded to three hydrogen atoms." [] synonym: "AMMONIA" EXACT [PDBeChem] synonym: "Ammonia" EXACT [KEGG_COMPOUND] xref: Beilstein:3587154 {source="Beilstein"} xref: CAS:7664-41-7 {source="ChemIDplus", source="KEGG COMPOUND", source="NIST Chemistry WebBook"} xref: Drug_Central:4625 {source="DrugCentral"} xref: Gmelin:79 {source="Gmelin"} xref: HMDB:HMDB0000051 xref: KEGG:C00014 xref: KEGG:D02916 xref: KNApSAcK:C00007267 xref: MetaCyc:AMMONIA xref: MolBase:930 xref: PDBeChem:NH3 xref: PMID:110589 {source="Europe PMC"} xref: PMID:11139349 {source="Europe PMC"} xref: PMID:11540049 {source="Europe PMC"} xref: PMID:11746427 {source="Europe PMC"} xref: PMID:11783653 {source="Europe PMC"} xref: PMID:13753780 {source="Europe PMC"} xref: PMID:14663195 {source="Europe PMC"} xref: PMID:15092448 {source="Europe PMC"} xref: PMID:15094021 {source="Europe PMC"} xref: PMID:15554424 {source="Europe PMC"} xref: PMID:15969015 {source="Europe PMC"} xref: PMID:16008360 {source="Europe PMC"} xref: PMID:16050680 {source="Europe PMC"} xref: PMID:16348008 {source="Europe PMC"} xref: PMID:16349403 {source="Europe PMC"} xref: PMID:16614889 {source="Europe PMC"} xref: PMID:16664306 {source="Europe PMC"} xref: PMID:16842901 {source="Europe PMC"} xref: PMID:17025297 {source="Europe PMC"} xref: PMID:17439666 {source="Europe PMC"} xref: PMID:17569513 {source="Europe PMC"} xref: PMID:17737668 {source="Europe PMC"} xref: PMID:18670398 {source="Europe PMC"} xref: PMID:22002069 {source="Europe PMC"} xref: PMID:22081570 {source="Europe PMC"} xref: PMID:22088435 {source="Europe PMC"} xref: PMID:22100291 {source="Europe PMC"} xref: PMID:22130175 {source="Europe PMC"} xref: PMID:22150211 {source="Europe PMC"} xref: PMID:22240068 {source="Europe PMC"} xref: PMID:22290316 {source="Europe PMC"} xref: PMID:22342082 {source="Europe PMC"} xref: PMID:22385337 {source="Europe PMC"} xref: PMID:22443779 {source="Europe PMC"} xref: PMID:22560242 {source="Europe PMC"} xref: Reaxys:3587154 {source="Reaxys"} xref: Wikipedia:Ammonia is_a: BFO:0000004 ! independent continuant is_a: CHEBI:138675 ! gas molecular entity is_a: CHEBI:35107 ! azane is_a: CHEBI:37176 ! mononuclear parent hydride relationship: is_conjugate_acid_of CHEBI:29337 ! azanide relationship: is_conjugate_base_of CHEBI:28938 ! ammonium relationship: RO:0000087 CHEBI:50910 ! has role neurotoxin relationship: RO:0000087 CHEBI:59740 ! has role nucleophilic reagent relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite relationship: RO:0000087 CHEBI:77941 ! has role EC 3.5.1.4 (amidase) inhibitor relationship: RO:0000087 CHEBI:78433 ! has role refrigerant [Term] id: CHEBI:16189 name: sulfate namespace: chebi_ontology def: "A sulfur oxoanion obtained by deprotonation of both OH groups of sulfuric acid." [] synonym: "Sulfate" EXACT [KEGG_COMPOUND] synonym: "sulfate" EXACT [UniProt] xref: Beilstein:3648446 {source="Beilstein"} xref: CAS:14808-79-8 {source="ChemIDplus", source="NIST Chemistry WebBook"} xref: Gmelin:2120 {source="Gmelin"} xref: HMDB:HMDB0001448 xref: KEGG:C00059 xref: KEGG:D05963 xref: MetaCyc:SULFATE xref: PDBeChem:SO4 xref: PMID:11200094 {source="Europe PMC"} xref: PMID:11452993 {source="Europe PMC"} xref: PMID:11581495 {source="Europe PMC"} xref: PMID:11798107 {source="Europe PMC"} xref: PMID:12166931 {source="Europe PMC"} xref: PMID:12668033 {source="Europe PMC"} xref: PMID:14597181 {source="Europe PMC"} xref: PMID:15093386 {source="Europe PMC"} xref: PMID:15984785 {source="Europe PMC"} xref: PMID:16186560 {source="Europe PMC"} xref: PMID:16345535 {source="Europe PMC"} xref: PMID:16347366 {source="Europe PMC"} xref: PMID:16348007 {source="Europe PMC"} xref: PMID:16483812 {source="Europe PMC"} xref: PMID:16534979 {source="Europe PMC"} xref: PMID:16656509 {source="Europe PMC"} xref: PMID:16742508 {source="Europe PMC"} xref: PMID:16742518 {source="Europe PMC"} xref: PMID:17120760 {source="Europe PMC"} xref: PMID:17420092 {source="Europe PMC"} xref: PMID:17439666 {source="Europe PMC"} xref: PMID:17709180 {source="Europe PMC"} xref: PMID:18398178 {source="Europe PMC"} xref: PMID:18815700 {source="Europe PMC"} xref: PMID:18846414 {source="Europe PMC"} xref: PMID:19047345 {source="Europe PMC"} xref: PMID:19244483 {source="Europe PMC"} xref: PMID:19544990 {source="Europe PMC"} xref: PMID:19628332 {source="Europe PMC"} xref: PMID:19812358 {source="Europe PMC"} xref: PMID:30398859 {source="Europe PMC"} xref: Reaxys:3648446 {source="Reaxys"} xref: Wikipedia:Sulfate is_a: BFO:0000004 ! independent continuant is_a: CHEBI:33482 ! sulfur oxoanion is_a: CHEBI:48154 ! sulfur oxide is_a: CHEBI:79388 ! divalent inorganic anion relationship: is_conjugate_base_of CHEBI:45696 ! hydrogensulfate relationship: RO:0000087 CHEBI:23357 ! has role cofactor relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite relationship: RO:0000087 CHEBI:77746 ! has role human metabolite [Term] id: CHEBI:16336 name: hyaluronic acid namespace: chebi_ontology def: "A mucopolysaccharide composed of N-acetylglucosamine and glucuronic acid subunits. It is found in the connective tissues of vertebrates. A principal constituent of the extracellular matrix (ECM), it mediates the growth and metastasis of tumour cells." [] synonym: "Hyaluronic acid" EXACT [KEGG_COMPOUND] xref: Beilstein:8538277 {source="Beilstein"} xref: CAS:9004-61-9 {source="ChemIDplus", source="KEGG COMPOUND"} xref: HMDB:HMDB0010366 xref: KEGG:C00518 xref: KEGG:D08043 xref: KEGG:G10505 xref: PMID:11122186 {source="Europe PMC"} xref: PMID:18056362 {source="Europe PMC"} xref: PMID:18290544 {source="Europe PMC"} xref: Reaxys:8187837 {source="Reaxys"} xref: Wikipedia:Hyaluronan is_a: BFO:0000004 ! independent continuant is_a: CHEBI:37395 ! mucopolysaccharide is_a: CHEBI:72813 ! exopolysaccharide relationship: is_conjugate_acid_of CHEBI:132153 ! hyaluronate relationship: RO:0000087 CHEBI:77746 ! has role human metabolite [Term] id: CHEBI:16541 name: protein polypeptide chain namespace: chebi_ontology def: "A naturally occurring polypeptide synthesized at the ribosome." [] xref: KEGG:C00017 is_a: CHEBI:15841 ! polypeptide relationship: BFO:0000051 CHEBI:33700 ! has part proteinogenic amino-acid residue [Term] id: CHEBI:16646 name: carbohydrate namespace: chebi_ontology def: "Any member of the class of organooxygen compounds that is a polyhydroxy-aldehyde or -ketone or a lactol resulting from their intramolecular condensation (monosaccharides); substances derived from these by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom; and polymeric products arising by intermolecular acetal formation between two or more such molecules (disaccharides, polysaccharides and oligosaccharides). Carbohydrates contain only carbon, hydrogen and oxygen atoms; prior to any oxidation or reduction, most have the empirical formula Cm(H2O)n. Compounds obtained from carbohydrates by substitution, etc., are known as carbohydrate derivatives and may contain other elements. Cyclitols are generally not regarded as carbohydrates." [] xref: Wikipedia:Carbohydrate is_a: CHEBI:78616 ! carbohydrates and carbohydrate derivatives [Term] id: CHEBI:16670 name: peptide namespace: chebi_ontology def: "Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from alpha-amino acids, but it includes those derived from any amino carboxylic acid. X = OH, OR, NH2, NHR, etc." [] synonym: "Peptide" EXACT [KEGG_COMPOUND] xref: KEGG:C00012 is_a: CHEBI:37622 ! carboxamide is_a: CHEBI:50047 ! organic amino compound relationship: BFO:0000051 CHEBI:33708 ! has part amino-acid residue relationship: is_tautomer_of CHEBI:60466 ! peptide zwitterion [Term] id: CHEBI:166902 name: noradrenaline(1+) namespace: chebi_ontology is_a: CHEBI:25697 ! organic cation is_a: CHEBI:35274 ! ammonium ion derivative relationship: is_conjugate_acid_of CHEBI:33569 ! noradrenaline [Term] id: CHEBI:167559 name: glycan namespace: chebi_ontology def: "Any oligosaccharide, polysaccharide or their derivatives consisting of monosaccharides or monosaccharide derivatives linked by glycosidic bonds. See also http://www.ontobee.org/ontology/GNO?iri=http://purl.obolibrary.org/obo/GNO_00000001." [] is_a: CHEBI:78616 ! carbohydrates and carbohydrate derivatives [Term] id: CHEBI:16765 name: tryptamine namespace: chebi_ontology def: "An aminoalkylindole consisting of indole having a 2-aminoethyl group at the 3-position." [] synonym: "Tryptamine" EXACT [KEGG_COMPOUND] xref: Beilstein:125513 {source="Beilstein"} xref: CAS:61-54-1 {source="ChemIDplus", source="KEGG COMPOUND", source="NIST Chemistry WebBook"} xref: DrugBank:DB08653 xref: Gmelin:603448 {source="Gmelin"} xref: HMDB:HMDB0000303 xref: KEGG:C00398 xref: KNApSAcK:C00001434 xref: MetaCyc:TRYPTAMINE xref: PDBeChem:TSS xref: PMID:16126914 {source="Europe PMC"} xref: PMID:22770225 {source="Europe PMC"} xref: PMID:24345948 {source="Europe PMC"} xref: PMID:24558969 {source="Europe PMC"} xref: Reaxys:125513 {source="Reaxys"} xref: Wikipedia:Tryptamine is_a: CHEBI:27162 ! tryptamines is_a: CHEBI:38631 ! aminoalkylindole is_a: CHEBI:38958 ! indole alkaloid is_a: CHEBI:64365 ! aralkylamino compound relationship: is_conjugate_base_of CHEBI:57887 ! tryptaminium relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite relationship: RO:0000087 CHEBI:77746 ! has role human metabolite [Term] id: CHEBI:16990 name: bilirubin IXalpha namespace: chebi_ontology def: "A member of the class of biladienes that is a linear tetrapyrrole with the dipyrrole units being of both exovinyl and endovinyl type. A product of heme degradation, it is produced in the reticuloendothelial system by the reduction of biliverdin and transported to the liver as a complex with serum albumin." [] xref: Beilstein:74376 {source="Beilstein"} xref: CAS:635-65-4 {source="ChemIDplus", source="KEGG COMPOUND"} xref: Gmelin:411033 {source="Gmelin"} xref: HMDB:HMDB0000054 xref: KEGG:C00486 xref: KNApSAcK:C00029828 xref: MetaCyc:BILIRUBIN xref: PDBeChem:BLR xref: PMID:12799017 {source="Europe PMC"} xref: PMID:18442622 {source="Europe PMC"} xref: PMID:23763371 {source="Europe PMC"} xref: PMID:23768684 {source="Europe PMC"} xref: PMID:30224965 {source="Europe PMC"} xref: PMID:8605219 {source="Europe PMC"} xref: PMID:9587403 {source="Europe PMC"} xref: Reaxys:74376 {source="Reaxys"} xref: Wikipedia:Bilirubin is_a: CHEBI:35692 ! dicarboxylic acid is_a: CHEBI:36735 ! biladienes relationship: BFO:0000051 CHEBI:142163 ! has part 24G7 epitope relationship: is_conjugate_acid_of CHEBI:57977 ! bilirubin(2-) relationship: RO:0000087 CHEBI:22586 ! has role antioxidant relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite relationship: RO:0000087 CHEBI:77746 ! has role human metabolite [Term] id: CHEBI:16991 name: deoxyribonucleic acid namespace: chebi_ontology def: "High molecular weight, linear polymers, composed of nucleotides containing deoxyribose and linked by phosphodiester bonds; DNA contain the genetic information of organisms." [] synonym: "Deoxyribonucleic acid" EXACT [KEGG_COMPOUND] xref: CAS:9007-49-2 {source="ChemIDplus", source="KEGG COMPOUND"} xref: KEGG:C00039 is_a: BFO:0000004 ! independent continuant is_a: CHEBI:33696 ! nucleic acid relationship: BFO:0000051 CHEBI:33793 ! has part canonical deoxyribonucleoside residue relationship: BFO:0000051 CHEBI:50298 ! has part canonical deoxyribonucleotide residue relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite relationship: RO:0000087 CHEBI:77746 ! has role human metabolite [Term] id: CHEBI:17029 name: chitin namespace: chebi_ontology def: "An aminoglycan consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues." [] synonym: "Chitin" EXACT [KEGG_COMPOUND] synonym: "chitin" EXACT [IUPAC, UniProt] xref: CAS:1398-61-4 {source="KEGG COMPOUND"} xref: KEGG:C00461 xref: KEGG:G10483 is_a: BFO:0000004 ! independent continuant is_a: CHEBI:21638 ! N-acylglucosamine is_a: CHEBI:22506 ! aminoglycan relationship: RO:0000087 CHEBI:73336 ! has role vulnerary relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite relationship: RO:0000087 CHEBI:77746 ! has role human metabolite [Term] id: CHEBI:17087 name: ketone namespace: chebi_ontology def: "A compound in which a carbonyl group is bonded to two carbon atoms: R2C=O (neither R may be H)." [] synonym: "Ketone" EXACT [KEGG_COMPOUND] xref: KEGG:C01450 xref: Wikipedia:Ketone is_a: CHEBI:36586 ! carbonyl compound [Term] id: CHEBI:17089 name: glycoprotein namespace: chebi_ontology def: "A compound in which a carbohydrate component is covalently bound to a protein component." [] synonym: "Glycoprotein" EXACT [KEGG_COMPOUND] xref: KEGG:C00326 is_a: CHEBI:33837 ! conjugated protein is_a: CHEBI:63299 ! carbohydrate derivative [Term] id: CHEBI:17234 name: glucose namespace: chebi_ontology def: "An aldohexose used as a source of energy and metabolic intermediate." [] synonym: "Glucose" EXACT [KEGG_COMPOUND] xref: CAS:50-99-7 {source="KEGG COMPOUND"} xref: KEGG:C00293 xref: Wikipedia:Glucose is_a: BFO:0000004 ! independent continuant is_a: CHEBI:33917 ! aldohexose relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite [Term] id: CHEBI:17544 name: hydrogencarbonate namespace: chebi_ontology def: "The carbon oxoanion resulting from the removal of a proton from carbonic acid." [] synonym: "Hydrogencarbonate" EXACT [KEGG_COMPOUND] synonym: "hydrogencarbonate" EXACT [UniProt] xref: Beilstein:3903504 {source="Beilstein"} xref: CAS:71-52-3 {source="ChemIDplus"} xref: Gmelin:49249 {source="Gmelin"} xref: HMDB:HMDB0000595 xref: KEGG:C00288 xref: MetaCyc:HCO3 xref: PDBeChem:BCT xref: PMID:17215880 {source="Europe PMC"} xref: PMID:17505962 {source="Europe PMC"} xref: PMID:18439416 {source="Europe PMC"} xref: PMID:28732801 {source="Europe PMC"} xref: PMID:29150416 {source="Europe PMC"} xref: PMID:29460248 {source="Europe PMC"} xref: PMID:29466234 {source="Europe PMC"} xref: PMID:4208463 {source="Europe PMC"} xref: Wikipedia:Bicarbonate is_a: BFO:0000004 ! independent continuant is_a: CHEBI:35604 ! carbon oxoanion relationship: is_conjugate_acid_of CHEBI:41609 ! carbonate relationship: is_conjugate_base_of CHEBI:28976 ! carbonic acid relationship: RO:0000087 CHEBI:23357 ! has role cofactor relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite relationship: RO:0000087 CHEBI:77746 ! has role human metabolite [Term] id: CHEBI:17891 name: donor namespace: chebi_ontology def: "A molecular entity that can transfer (\"donate\") an electron, a pair of electrons, an atom or a group to another molecular entity." [] synonym: "Donor" EXACT [KEGG_COMPOUND] xref: KEGG:C01351 is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:18059 name: lipid namespace: chebi_ontology def: "'Lipids' is a loosely defined term for substances of biological origin that are soluble in nonpolar solvents. They consist of saponifiable lipids, such as glycerides (fats and oils) and phospholipids, as well as nonsaponifiable lipids, principally steroids." [] synonym: "Lipid" EXACT [KEGG_COMPOUND] xref: KEGG:C01356 is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:18085 name: glycosaminoglycan namespace: chebi_ontology def: "Any polysaccharide containing a substantial proportion of aminomonosaccharide residues." [] synonym: "Glycosaminoglycan" EXACT [KEGG_COMPOUND] xref: KEGG:C02545 xref: Wikipedia:Glycosaminoglycan is_a: CHEBI:22506 ! aminoglycan [Term] id: CHEBI:18133 name: hexose namespace: chebi_ontology def: "Any six-carbon monosaccharide which in its linear form contains either an aldehyde group at position 1 (aldohexose) or a ketone group at position 2 (ketohexose)." [] synonym: "Hexose" EXACT [KEGG_COMPOUND] xref: GlyGen:G70994MS xref: GlyTouCan:G70994MS xref: KEGG:C00738 is_a: CHEBI:35381 ! monosaccharide [Term] id: CHEBI:18154 name: polysaccharide namespace: chebi_ontology def: "A biomacromolecule consisting of large numbers of monosaccharide residues linked glycosidically. This term is commonly used only for those containing more than ten monosaccharide residues." [] synonym: "Polysaccharide" EXACT [KEGG_COMPOUND] xref: KEGG:C00420 is_a: CHEBI:16646 ! carbohydrate is_a: CHEBI:167559 ! glycan is_a: CHEBI:33694 ! biomacromolecule [Term] id: CHEBI:18282 name: nucleobase namespace: chebi_ontology def: "That part of DNA or RNA that may be involved in pairing." [] xref: KEGG:C00701 xref: Wikipedia:Nucleobase is_a: CHEBI:38101 ! organonitrogen heterocyclic compound [Term] id: CHEBI:18357 name: (R)-noradrenaline namespace: chebi_ontology def: "The R-enantiomer of noradrenaline." [] xref: Beilstein:2804840 {source="Beilstein"} xref: Beilstein:4231961 {source="ChemIDplus"} xref: CAS:51-41-2 {source="ChemIDplus", source="KEGG COMPOUND"} xref: Drug_Central:1960 {source="DrugCentral"} xref: DrugBank:DB00368 xref: HMDB:HMDB0000216 xref: KEGG:C00547 xref: KEGG:D00076 xref: KNApSAcK:C00001424 xref: PDBeChem:LNR xref: Reaxys:2804840 {source="Reaxys"} xref: Wikipedia:Norepinephrine is_a: CHEBI:33569 ! noradrenaline relationship: is_conjugate_base_of CHEBI:72587 ! (R)-noradrenaline(1+) relationship: is_enantiomer_of CHEBI:33571 ! (S)-noradrenaline relationship: RO:0000087 CHEBI:25512 ! has role neurotransmitter relationship: RO:0000087 CHEBI:35524 ! has role sympathomimetic agent relationship: RO:0000087 CHEBI:35569 ! has role alpha-adrenergic agonist relationship: RO:0000087 CHEBI:50514 ! has role vasoconstrictor agent relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite [Term] id: CHEBI:18367 name: phosphate(3-) namespace: chebi_ontology def: "A phosphate ion that is the conjugate base of hydrogenphosphate." [] xref: Beilstein:3903772 {source="Beilstein"} xref: CAS:14265-44-2 {source="ChemIDplus", source="KEGG COMPOUND"} xref: Gmelin:1997 {source="Gmelin"} xref: KEGG:C00009 xref: PDBeChem:PO4 {source="ChEBI"} xref: Reaxys:3903772 {source="Reaxys"} is_a: CHEBI:35780 ! phosphate ion is_a: CHEBI:79387 ! trivalent inorganic anion relationship: is_conjugate_base_of CHEBI:43474 ! hydrogenphosphate [Term] id: CHEBI:20664 name: 5beta-cholane namespace: chebi_ontology xref: Beilstein:2048472 {source="Beilstein"} is_a: CHEBI:35519 ! cholane [Term] id: CHEBI:21638 name: N-acylglucosamine namespace: chebi_ontology synonym: "N-acylglucosamine" EXACT [ChEBI] is_a: CHEBI:21656 ! N-acyl-hexosamine is_a: CHEBI:24271 ! glucosamines [Term] id: CHEBI:21656 name: N-acyl-hexosamine namespace: chebi_ontology synonym: "N-acyl-hexosamine" EXACT [ChEBI] is_a: CHEBI:24586 ! hexosamine [Term] id: CHEBI:22221 name: acyl group namespace: chebi_ontology def: "An organic group formed by removing one or more hydroxy groups from an oxoacid that has the general structure RkE(=O)l(OH)m (l =/= 0). Although the term is almost always applied to organic compounds, with carboxylic acid as the oxoacid, acyl groups can in principle be derived from other types of acids such as sulfonic acids or phosphonic acids." [] synonym: "acyl group" EXACT [IUPAC] is_a: CHEBI:33247 ! organic group [Term] id: CHEBI:22314 name: alkali metal atom namespace: chebi_ontology is_a: CHEBI:33318 ! main group element atom is_a: CHEBI:33521 ! metal atom is_a: CHEBI:33559 ! s-block element atom [Term] id: CHEBI:22315 name: alkaloid namespace: chebi_ontology def: "Any of the naturally occurring, basic nitrogen compounds (mostly heterocyclic) occurring mostly in the plant kingdom, but also found in bacteria, fungi, and animals. By extension, certain neutral compounds biogenetically related to basic alkaloids are also classed as alkaloids. Amino acids, peptides, proteins, nucleotides, nucleic acids, amino sugars and antibiotics are not normally regarded as alkaloids. Compounds in which the nitrogen is exocyclic (dopamine, mescaline, serotonin, etc.) are usually classed as amines rather than alkaloids." [] synonym: "Alkaloid" EXACT [ChEBI] xref: Wikipedia:Alkaloid is_a: BFO:0000004 ! independent continuant is_a: CHEBI:35352 ! organonitrogen compound relationship: RO:0000087 CHEBI:25212 ! has role metabolite [Term] id: CHEBI:22506 name: aminoglycan namespace: chebi_ontology is_a: CHEBI:35352 ! organonitrogen compound is_a: CHEBI:65212 ! polysaccharide derivative [Term] id: CHEBI:22563 name: anion namespace: chebi_ontology def: "A monoatomic or polyatomic species having one or more elementary charges of the electron." [] synonym: "Anion" EXACT [ChEBI] synonym: "anion" EXACT [ChEBI] is_a: CHEBI:24870 ! ion [Term] id: CHEBI:22586 name: antioxidant namespace: chebi_ontology def: "A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides." [] is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:22695 name: base namespace: chebi_ontology def: "A molecular entity having an available pair of electrons capable of forming a covalent bond with a hydron (Bronsted base) or with the vacant orbital of some other molecular entity (Lewis base)." [] synonym: "Base" EXACT [ChEBI] synonym: "base" EXACT [ChEBI] xref: KEGG:C00701 is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:22728 name: benzopyrrole namespace: chebi_ontology is_a: CHEBI:27171 ! organic heterobicyclic compound is_a: CHEBI:38101 ! organonitrogen heterocyclic compound is_a: CHEBI:38180 ! polycyclic heteroarene [Term] id: CHEBI:22868 name: bile salt namespace: chebi_ontology def: "A sodium salt of the conjugate of any bile acid with either glycine or taurine." [] xref: KEGG:C01558 is_a: CHEBI:36078 ! cholanoid is_a: CHEBI:38700 ! organic sodium salt [Term] id: CHEBI:23004 name: carbamoyl group namespace: chebi_ontology def: "The univalent carboacyl group formed by loss of -OH from the carboxy group of carbamic acid." [] xref: PMID:24168430 {source="Europe PMC"} is_a: CHEBI:27207 ! univalent carboacyl group relationship: is_substituent_group_from CHEBI:28616 ! carbamic acid [Term] id: CHEBI:23019 name: carbonyl group namespace: chebi_ontology synonym: "carbonyl group" EXACT [ChEBI, UniProt] is_a: CHEBI:51422 ! organodiyl group [Term] id: CHEBI:23357 name: cofactor namespace: chebi_ontology def: "An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group)." [] synonym: "cofactor" EXACT [IUPAC] xref: Wikipedia:Cofactor_(biochemistry) is_a: CHEBI:52206 ! biochemical role [Term] id: CHEBI:23367 name: molecular entity namespace: chebi_ontology def: "Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity." [] is_a: CHEBI:24431 ! chemical entity [Term] id: CHEBI:23449 name: cyclic peptide namespace: chebi_ontology is_a: CHEBI:16670 ! peptide [Term] id: CHEBI:23888 name: drug namespace: chebi_ontology def: "Any substance which when absorbed into a living organism may modify one or more of its functions. The term is generally accepted for a substance taken for a therapeutic purpose, but is also commonly used for abused substances." [] is_a: CHEBI:52217 ! pharmaceutical [Term] id: CHEBI:23906 name: monoatomic cation namespace: chebi_ontology is_a: CHEBI:24867 ! monoatomic ion is_a: CHEBI:36916 ! cation [Term] id: CHEBI:23924 name: enzyme inhibitor namespace: chebi_ontology def: "A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction." [] is_a: CHEBI:35222 ! inhibitor is_a: CHEBI:52206 ! biochemical role [Term] id: CHEBI:24271 name: glucosamines namespace: chebi_ontology def: "Any hexosamine that is glucose in which at least one of the hydroxy groups has been replaced by an amino group." [] is_a: CHEBI:24586 ! hexosamine [Term] id: CHEBI:24384 name: glycogens namespace: chebi_ontology is_a: CHEBI:37163 ! glucan [Term] id: CHEBI:24431 name: chemical entity namespace: chebi_ontology namespace: protein def: "A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances." [] synonym: "chemical entity" EXACT [UniProt] [Term] id: CHEBI:24432 name: biological role namespace: chebi_ontology def: "A role played by the molecular entity or part thereof within a biological context." [] is_a: CHEBI:50906 ! role [Term] id: CHEBI:24433 name: group namespace: chebi_ontology def: "A defined linked collection of atoms or a single atom within a molecular entity." [] is_a: CHEBI:24431 ! chemical entity relationship: BFO:0000051 CHEBI:33250 ! has part atom [Term] id: CHEBI:24532 name: organic heterocyclic compound namespace: chebi_ontology def: "A cyclic compound having as ring members atoms of carbon and at least of one other element." [] is_a: CHEBI:33285 ! heteroorganic entity is_a: CHEBI:33832 ! organic cyclic compound is_a: CHEBI:5686 ! heterocyclic compound [Term] id: CHEBI:24533 name: heterodetic cyclic peptide namespace: chebi_ontology def: "A heterodetic cyclic peptide is a peptide consisting only of amino-acid residues, but in which the linkages forming the ring are not solely peptide bonds; one or more is an isopeptide, disulfide, ester, or other bond." [] is_a: CHEBI:23449 ! cyclic peptide [Term] id: CHEBI:24586 name: hexosamine namespace: chebi_ontology def: "Any 6-carbon amino monosaccharide with at least one alcoholic hydroxy group replaced by an amino group." [] synonym: "hexosamine" EXACT [ChEBI] is_a: CHEBI:60926 ! amino monosaccharide [Term] id: CHEBI:24621 name: hormone namespace: chebi_ontology def: "Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds." [] is_a: CHEBI:33280 ! molecular messenger is_a: CHEBI:48705 ! agonist [Term] id: CHEBI:24651 name: hydroxides namespace: chebi_ontology def: "Hydroxides are chemical compounds containing a hydroxy group or salts containing hydroxide (OH(-))." [] is_a: CHEBI:25806 ! oxygen molecular entity is_a: CHEBI:33608 ! hydrogen molecular entity is_a: CHEBI:37577 ! heteroatomic molecular entity relationship: BFO:0000051 CHEBI:43176 ! has part hydroxy group [Term] id: CHEBI:24663 name: hydroxy-5beta-cholanic acid namespace: chebi_ontology def: "Any member of the class of 5beta-cholanic acids carrying at least one hydroxy group at unspecified position." [] is_a: CHEBI:33822 ! organic hydroxy compound is_a: CHEBI:36248 ! 5beta-cholanic acids relationship: has_functional_parent CHEBI:36238 ! 5beta-cholanic acid [Term] id: CHEBI:24828 name: indoles namespace: chebi_ontology def: "Any compound containing an indole skeleton." [] is_a: CHEBI:22728 ! benzopyrrole [Term] id: CHEBI:24833 name: oxoacid namespace: chebi_ontology def: "A compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons)." [] is_a: BFO:0000004 ! independent continuant is_a: CHEBI:24651 ! hydroxides relationship: RO:0000087 CHEBI:39141 ! has role Bronsted acid [Term] id: CHEBI:24834 name: inorganic anion namespace: chebi_ontology is_a: CHEBI:22563 ! anion is_a: CHEBI:36914 ! inorganic ion [Term] id: CHEBI:24835 name: inorganic molecular entity namespace: chebi_ontology def: "A molecular entity that contains no carbon." [] is_a: CHEBI:23367 ! molecular entity [Term] id: CHEBI:24836 name: inorganic oxide namespace: chebi_ontology is_a: CHEBI:24835 ! inorganic molecular entity is_a: CHEBI:25741 ! oxide [Term] id: CHEBI:24866 name: salt namespace: chebi_ontology def: "A salt is an assembly of cations and anions." [] is_a: CHEBI:37577 ! heteroatomic molecular entity relationship: BFO:0000051 CHEBI:22563 ! has part anion relationship: BFO:0000051 CHEBI:36916 ! has part cation [Term] id: CHEBI:24867 name: monoatomic ion namespace: chebi_ontology is_a: CHEBI:24870 ! ion is_a: CHEBI:33238 ! monoatomic entity [Term] id: CHEBI:24868 name: organic salt namespace: chebi_ontology is_a: CHEBI:24866 ! salt [Term] id: CHEBI:24870 name: ion namespace: chebi_ontology def: "A molecular entity having a net electric charge." [] synonym: "Ion" EXACT [ChEBI] synonym: "ion" EXACT [ChEBI] is_a: CHEBI:23367 ! molecular entity [Term] id: CHEBI:25046 name: linear tetrapyrrole namespace: chebi_ontology is_a: CHEBI:26932 ! tetrapyrrole [Term] id: CHEBI:25212 name: metabolite namespace: chebi_ontology def: "Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites." [] is_a: CHEBI:52206 ! biochemical role [Term] id: CHEBI:25213 name: metal cation namespace: chebi_ontology is_a: CHEBI:23906 ! monoatomic cation is_a: CHEBI:36915 ! inorganic cation [Term] id: CHEBI:25362 name: elemental molecule namespace: chebi_ontology def: "A molecule all atoms of which have the same atomic number." [] is_a: CHEBI:25367 ! molecule is_a: CHEBI:33259 ! elemental molecular entity [Term] id: CHEBI:25367 name: molecule namespace: chebi_ontology def: "Any polyatomic entity that is an electrically neutral entity consisting of more than one atom." [] synonym: "molecule" EXACT [IUPAC] is_a: CHEBI:36357 ! polyatomic entity [Term] id: CHEBI:25375 name: monoamine molecular messenger namespace: chebi_ontology def: "A group of neurotransmitters and neuromodulators that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan." [] is_a: CHEBI:63534 ! monoamine relationship: RO:0000087 CHEBI:33280 ! has role molecular messenger [Term] id: CHEBI:25384 name: monocarboxylic acid namespace: chebi_ontology def: "An oxoacid containing a single carboxy group." [] is_a: CHEBI:33575 ! carboxylic acid relationship: is_conjugate_acid_of CHEBI:35757 ! monocarboxylic acid anion [Term] id: CHEBI:25414 name: monoatomic monocation namespace: chebi_ontology is_a: CHEBI:23906 ! monoatomic cation [Term] id: CHEBI:25512 name: neurotransmitter namespace: chebi_ontology def: "An endogenous compound that is used to transmit information across the synapse between a neuron and another cell." [] xref: Wikipedia:Neurotransmitter is_a: CHEBI:33280 ! molecular messenger [Term] id: CHEBI:25555 name: nitrogen atom namespace: chebi_ontology xref: WebElements:N is_a: BFO:0000004 ! independent continuant is_a: CHEBI:25585 ! nonmetal atom is_a: CHEBI:33300 ! pnictogen relationship: RO:0000087 CHEBI:33937 ! has role macronutrient [Term] id: CHEBI:25585 name: nonmetal atom namespace: chebi_ontology is_a: CHEBI:33250 ! atom [Term] id: CHEBI:25696 name: organic anion namespace: chebi_ontology def: "Any organic ion with a net negative charge." [] is_a: CHEBI:22563 ! anion is_a: CHEBI:25699 ! organic ion [Term] id: CHEBI:25697 name: organic cation namespace: chebi_ontology def: "Any organic ion with a net positive charge." [] is_a: CHEBI:25699 ! organic ion is_a: CHEBI:36916 ! cation [Term] id: CHEBI:25699 name: organic ion namespace: chebi_ontology is_a: CHEBI:24870 ! ion is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:25704 name: organic sulfate namespace: chebi_ontology def: "Compounds of the general formula SO3HOR where R is an organyl group" [] is_a: CHEBI:26820 ! sulfates relationship: is_conjugate_acid_of CHEBI:58958 ! organosulfate oxoanion [Term] id: CHEBI:25741 name: oxide namespace: chebi_ontology def: "An oxide is a chemical compound of oxygen with other chemical elements." [] synonym: "oxide" EXACT [ChEBI] is_a: CHEBI:25806 ! oxygen molecular entity is_a: CHEBI:37577 ! heteroatomic molecular entity [Term] id: CHEBI:25805 name: oxygen atom namespace: chebi_ontology xref: KEGG:C00007 xref: WebElements:O is_a: BFO:0000004 ! independent continuant is_a: CHEBI:25585 ! nonmetal atom is_a: CHEBI:33303 ! chalcogen relationship: RO:0000087 CHEBI:33937 ! has role macronutrient [Term] id: CHEBI:25806 name: oxygen molecular entity namespace: chebi_ontology synonym: "oxygen molecular entity" EXACT [ChEBI] is_a: CHEBI:33304 ! chalcogen molecular entity relationship: BFO:0000051 CHEBI:25805 ! has part oxygen atom [Term] id: CHEBI:25905 name: peptide hormone namespace: chebi_ontology def: "Any peptide with hormonal activity in animals, whether endocrine, neuroendocrine, or paracrine." [] is_a: CHEBI:16670 ! peptide relationship: RO:0000087 CHEBI:24621 ! has role hormone [Term] id: CHEBI:26020 name: phosphate namespace: chebi_ontology def: "Salts and esters of phosphoric and oligophosphoric acids and their chalcogen analogues. In inorganic chemistry, the term is also used to describe anionic coordination entities with phosphorus as central atom." [] is_a: CHEBI:26079 ! phosphoric acid derivative [Term] id: CHEBI:26078 name: phosphoric acid namespace: chebi_ontology def: "A phosphorus oxoacid that consists of one oxo and three hydroxy groups joined covalently to a central phosphorus atom." [] synonym: "Phosphoric acid" EXACT [KEGG_COMPOUND] synonym: "phosphoric acid" EXACT [IUPAC] xref: Beilstein:1921286 {source="Beilstein"} xref: CAS:7664-38-2 {source="ChemIDplus", source="KEGG COMPOUND", source="NIST Chemistry WebBook"} xref: Drug_Central:4478 {source="DrugCentral"} xref: Gmelin:2000 {source="Gmelin"} xref: HMDB:HMDB0002142 xref: KEGG:C00009 xref: KEGG:D05467 xref: KNApSAcK:C00007408 xref: PMID:11455380 {source="Europe PMC"} xref: PMID:15630224 {source="Europe PMC"} xref: PMID:17439666 {source="Europe PMC"} xref: PMID:17518491 {source="Europe PMC"} xref: PMID:22282755 {source="Europe PMC"} xref: PMID:22333268 {source="Europe PMC"} xref: PMID:22381614 {source="Europe PMC"} xref: PMID:22401268 {source="Europe PMC"} xref: Reaxys:1921286 {source="Reaxys"} xref: Wikipedia:Phosphoric_Acid is_a: CHEBI:59698 ! phosphoric acids relationship: is_conjugate_acid_of CHEBI:39745 ! dihydrogenphosphate relationship: RO:0000087 CHEBI:33287 ! has role fertilizer relationship: RO:0000087 CHEBI:46787 ! has role solvent relationship: RO:0000087 CHEBI:77746 ! has role human metabolite relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite [Term] id: CHEBI:26079 name: phosphoric acid derivative namespace: chebi_ontology is_a: CHEBI:36359 ! phosphorus oxoacid derivative relationship: has_functional_parent CHEBI:26078 ! phosphoric acid [Term] id: CHEBI:26082 name: phosphorus molecular entity namespace: chebi_ontology is_a: CHEBI:33302 ! pnictogen molecular entity relationship: BFO:0000051 CHEBI:28659 ! has part phosphorus atom [Term] id: CHEBI:26708 name: sodium atom namespace: chebi_ontology xref: CAS:7440-23-5 {source="ChemIDplus"} xref: Gmelin:16221 {source="Gmelin"} xref: KEGG:C01330 xref: WebElements:Na is_a: BFO:0000004 ! independent continuant is_a: CHEBI:22314 ! alkali metal atom relationship: RO:0000087 CHEBI:33937 ! has role macronutrient relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite [Term] id: CHEBI:26712 name: sodium molecular entity namespace: chebi_ontology is_a: CHEBI:33296 ! alkali metal molecular entity relationship: BFO:0000051 CHEBI:26708 ! has part sodium atom [Term] id: CHEBI:26714 name: sodium salt namespace: chebi_ontology def: "Any alkali metal salt having sodium(1+) as the cation." [] is_a: CHEBI:26712 ! sodium molecular entity is_a: CHEBI:35479 ! alkali metal salt relationship: BFO:0000051 CHEBI:29101 ! has part sodium(1+) [Term] id: CHEBI:26764 name: steroid hormone namespace: chebi_ontology def: "Any steroid that acts as hormone." [] is_a: BFO:0000004 ! independent continuant is_a: CHEBI:35341 ! steroid relationship: RO:0000087 CHEBI:24621 ! has role hormone [Term] id: CHEBI:26819 name: sulfuric ester namespace: chebi_ontology def: "An ester of an alcohol and sulfuric acid." [] is_a: CHEBI:35701 ! ester is_a: CHEBI:37826 ! sulfuric acid derivative [Term] id: CHEBI:26820 name: sulfates namespace: chebi_ontology def: "Salts and esters of sulfuric acid" [] synonym: "sulfates" EXACT [ChEBI] is_a: CHEBI:37826 ! sulfuric acid derivative [Term] id: CHEBI:26833 name: sulfur atom namespace: chebi_ontology xref: CAS:7704-34-9 {source="ChemIDplus", source="NIST Chemistry WebBook"} xref: KEGG:C00087 xref: KEGG:D06527 xref: PPDB:605 xref: WebElements:S is_a: BFO:0000004 ! independent continuant is_a: CHEBI:25585 ! nonmetal atom is_a: CHEBI:33303 ! chalcogen relationship: RO:0000087 CHEBI:33937 ! has role macronutrient [Term] id: CHEBI:26835 name: sulfur molecular entity namespace: chebi_ontology synonym: "sulfur molecular entity" EXACT [ChEBI] is_a: CHEBI:33304 ! chalcogen molecular entity relationship: BFO:0000051 CHEBI:26833 ! has part sulfur atom [Term] id: CHEBI:26836 name: sulfuric acid namespace: chebi_ontology def: "A sulfur oxoacid that consists of two oxo and two hydroxy groups joined covalently to a central sulfur atom." [] synonym: "Sulfuric acid" EXACT [KEGG_COMPOUND] synonym: "sulfuric acid" EXACT [ChEBI] xref: CAS:7664-93-9 {source="ChemIDplus", source="KEGG COMPOUND", source="NIST Chemistry WebBook"} xref: Gmelin:2122 {source="Gmelin"} xref: KEGG:C00059 xref: KEGG:D05963 xref: KNApSAcK:C00007530 xref: MolBase:4 xref: PMID:13568755 {source="Europe PMC"} xref: PMID:16122922 {source="Europe PMC"} xref: PMID:19397353 {source="Europe PMC"} xref: PMID:22047659 {source="Europe PMC"} xref: PMID:22136045 {source="Europe PMC"} xref: PMID:22204399 {source="Europe PMC"} xref: PMID:22267186 {source="Europe PMC"} xref: PMID:22296037 {source="Europe PMC"} xref: PMID:22364556 {source="Europe PMC"} xref: PMID:22435616 {source="Europe PMC"} xref: PPDB:606 xref: Reaxys:2037554 {source="Reaxys"} xref: Wikipedia:Sulfuric_acid is_a: CHEBI:33402 ! sulfur oxoacid relationship: is_conjugate_acid_of CHEBI:45696 ! hydrogensulfate relationship: RO:0000087 CHEBI:35223 ! has role catalyst [Term] id: CHEBI:26932 name: tetrapyrrole namespace: chebi_ontology def: "A natural pigment containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next." [] is_a: CHEBI:33833 ! heteroarene is_a: CHEBI:38077 ! polypyrrole [Term] id: CHEBI:27027 name: micronutrient namespace: chebi_ontology def: "Any nutrient required in small quantities by organisms throughout their life in order to orchestrate a range of physiological functions." [] xref: Wikipedia:Micronutrient is_a: CHEBI:33284 ! nutrient [Term] id: CHEBI:27162 name: tryptamines namespace: chebi_ontology def: "Tryptamine and its substitution derivatives." [] is_a: CHEBI:24828 ! indoles [Term] id: CHEBI:27171 name: organic heterobicyclic compound namespace: chebi_ontology is_a: CHEBI:33672 ! heterobicyclic compound is_a: CHEBI:38166 ! organic heteropolycyclic compound [Term] id: CHEBI:27207 name: univalent carboacyl group namespace: chebi_ontology def: "A univalent carboacyl group is a group formed by loss of OH from the carboxy group of a carboxylic acid." [] is_a: CHEBI:37838 ! carboacyl group [Term] id: CHEBI:27369 name: zwitterion namespace: chebi_ontology def: "A neutral compound having formal unit electrical charges of opposite sign on non-adjacent atoms. Sometimes referred to as inner salts, dipolar ions (a misnomer)." [] is_a: CHEBI:51151 ! dipolar compound [Term] id: CHEBI:27594 name: carbon atom namespace: chebi_ontology xref: CAS:7440-44-0 {source="ChemIDplus", source="KEGG COMPOUND"} xref: KEGG:C06265 xref: WebElements:C is_a: BFO:0000004 ! independent continuant is_a: CHEBI:25585 ! nonmetal atom is_a: CHEBI:33306 ! carbon group element atom relationship: RO:0000087 CHEBI:33937 ! has role macronutrient [Term] id: CHEBI:28087 name: glycogen namespace: chebi_ontology def: "A polydisperse, highly branched glucan composed of chains of D-glucopyranose residues in alpha(1->4) glycosidic linkage, joined together by alpha(1->6) glycosidic linkages. A small number of alpha(1->3) glycosidic linkages and some cumulative alpha(1->6) links also may occur. The branches in glycogen typically contain 8 to 12 glucose residues." [] synonym: "Glycogen" EXACT [KEGG_COMPOUND] xref: CAS:9005-79-2 {source="ChemIDplus", source="KEGG COMPOUND"} xref: GlyGen:G99991IU xref: GlyTouCan:G99991IU xref: HMDB:HMDB0000757 xref: KEGG:C00182 xref: MetaCyc:CPD0-971 xref: Wikipedia:Glycogen is_a: BFO:0000004 ! independent continuant is_a: CHEBI:24384 ! glycogens relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite [Term] id: CHEBI:28616 name: carbamic acid namespace: chebi_ontology def: "A one-carbon compound that is ammonia in which one of the hydrogens is replaced by a carboxy group. Although carbamic acid derivatives are common, carbamic acid itself has never been synthesised." [] synonym: "CARBAMIC ACID" EXACT [PDBeChem] synonym: "Carbamic acid" EXACT [KEGG_COMPOUND] xref: Beilstein:1734754 {source="Beilstein"} xref: CAS:463-77-4 {source="ChemIDplus", source="KEGG COMPOUND"} xref: DrugBank:DB04261 xref: Gmelin:130345 {source="Gmelin"} xref: KEGG:C01563 xref: PDBeChem:OUT xref: Wikipedia:Carbamic_acid is_a: CHEBI:35352 ! organonitrogen compound is_a: CHEBI:35605 ! carbon oxoacid is_a: CHEBI:64708 ! one-carbon compound relationship: is_conjugate_acid_of CHEBI:13941 ! carbamate relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite [Term] id: CHEBI:28659 name: phosphorus atom namespace: chebi_ontology xref: CAS:7723-14-0 {source="ChemIDplus", source="KEGG COMPOUND"} xref: Gmelin:16235 {source="Gmelin"} xref: KEGG:C06262 xref: WebElements:P is_a: BFO:0000004 ! independent continuant is_a: CHEBI:25585 ! nonmetal atom is_a: CHEBI:33300 ! pnictogen relationship: RO:0000087 CHEBI:33937 ! has role macronutrient [Term] id: CHEBI:28790 name: serotonin namespace: chebi_ontology def: "A primary amino compound that is the 5-hydroxy derivative of tryptamine." [] synonym: "SEROTONIN" EXACT [PDBeChem] synonym: "Serotonin" EXACT [KEGG_COMPOUND] xref: Beilstein:143524 {source="Beilstein"} xref: CAS:50-67-9 {source="ChemIDplus", source="KEGG COMPOUND"} xref: Gmelin:1861995 {source="Gmelin"} xref: HMDB:HMDB0000259 xref: KEGG:C00780 xref: KNApSAcK:C00001429 xref: LINCS:LSM-6589 xref: MetaCyc:SEROTONIN xref: PDBeChem:SRO xref: PMID:18593914 {source="Europe PMC"} xref: PMID:22770225 {source="Europe PMC"} xref: PMID:24136337 {source="Europe PMC"} xref: Reaxys:143524 {source="Reaxys"} xref: Wikipedia:Serotonin is_a: CHEBI:25375 ! monoamine molecular messenger is_a: CHEBI:27162 ! tryptamines is_a: CHEBI:33853 ! phenols is_a: CHEBI:50994 ! primary amino compound is_a: CHEBI:84729 ! hydroxyindoles relationship: has_functional_parent CHEBI:16765 ! tryptamine relationship: is_conjugate_base_of CHEBI:350546 ! serotonin(1+) relationship: RO:0000087 CHEBI:25512 ! has role neurotransmitter relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite relationship: RO:0000087 CHEBI:77746 ! has role human metabolite [Term] id: CHEBI:28938 name: ammonium namespace: chebi_ontology def: "An onium cation obtained by protonation of ammonia." [] synonym: "ammonium" EXACT [ChEBI] xref: CAS:14798-03-9 {source="ChemIDplus", source="NIST Chemistry WebBook"} xref: Gmelin:84 {source="Gmelin"} xref: KEGG:C01342 xref: MetaCyc:AMMONIUM xref: MolBase:929 xref: PDBeChem:NH4 xref: PMID:11319011 {source="Europe PMC"} xref: PMID:11341317 {source="Europe PMC"} xref: PMID:12096804 {source="Europe PMC"} xref: PMID:14512268 {source="Europe PMC"} xref: PMID:14879753 {source="Europe PMC"} xref: PMID:16345391 {source="Europe PMC"} xref: PMID:16903292 {source="Europe PMC"} xref: PMID:17392693 {source="Europe PMC"} xref: PMID:18515490 {source="Europe PMC"} xref: PMID:19199063 {source="Europe PMC"} xref: PMID:19596600 {source="Europe PMC"} xref: PMID:19682559 {source="Europe PMC"} xref: PMID:19716251 {source="Europe PMC"} xref: PMID:21993530 {source="Europe PMC"} xref: PMID:22265469 {source="Europe PMC"} xref: PMID:22524020 {source="Europe PMC"} xref: PMID:22562341 {source="Europe PMC"} xref: PMID:22631217 {source="Europe PMC"} xref: Reaxys:16093784 {source="Reaxys"} xref: Wikipedia:Ammonium is_a: BFO:0000004 ! independent continuant is_a: CHEBI:35106 ! nitrogen hydride is_a: CHEBI:50313 ! onium cation is_a: CHEBI:60242 ! monovalent inorganic cation relationship: is_conjugate_acid_of CHEBI:16134 ! ammonia relationship: RO:0000087 CHEBI:23357 ! has role cofactor relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite relationship: RO:0000087 CHEBI:77746 ! has role human metabolite [Term] id: CHEBI:28963 name: amino sugar namespace: chebi_ontology def: "Any sugar having one or more alcoholic hydroxy groups replaced by substituted or unsubstituted amino groups." [] xref: KEGG:C05383 xref: PMID:18424273 {source="Europe PMC"} xref: PMID:9056391 {source="Europe PMC"} is_a: CHEBI:63299 ! carbohydrate derivative [Term] id: CHEBI:28965 name: dicarboxylic acid dianion namespace: chebi_ontology def: "A carboxylic acid dianion obtained by deprotonation of both carboxy groups of any dicarboxylic acid." [] synonym: "dicarboxylic acid dianion" EXACT [ChEBI] is_a: CHEBI:35693 ! dicarboxylic acid anion is_a: CHEBI:38716 ! carboxylic acid dianion [Term] id: CHEBI:28976 name: carbonic acid namespace: chebi_ontology synonym: "Carbonic acid" EXACT [KEGG_COMPOUND] xref: CAS:463-79-6 {source="ChemIDplus", source="KEGG COMPOUND"} xref: Gmelin:25554 {source="Gmelin"} xref: KEGG:C01353 xref: PDBeChem:CO3 is_a: CHEBI:35605 ! carbon oxoacid is_a: CHEBI:36961 ! chalcocarbonic acid relationship: is_conjugate_acid_of CHEBI:17544 ! hydrogencarbonate relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite [Term] id: CHEBI:29067 name: carboxylic acid anion namespace: chebi_ontology def: "The conjugate base formed when the carboxy group of a carboxylic acid is deprotonated." [] is_a: CHEBI:25696 ! organic anion is_a: CHEBI:35406 ! oxoanion relationship: is_conjugate_base_of CHEBI:33575 ! carboxylic acid [Term] id: CHEBI:29101 name: sodium(1+) namespace: chebi_ontology def: "A monoatomic monocation obtained from sodium." [] xref: CAS:17341-25-2 {source="ChemIDplus", source="NIST Chemistry WebBook"} xref: Gmelin:15196 {source="Gmelin"} xref: KEGG:C01330 xref: PDBeChem:NA is_a: BFO:0000004 ! independent continuant is_a: CHEBI:25414 ! monoatomic monocation is_a: CHEBI:33504 ! alkali metal cation is_a: CHEBI:37246 ! elemental sodium is_a: CHEBI:60242 ! monovalent inorganic cation relationship: RO:0000087 CHEBI:23357 ! has role cofactor relationship: RO:0000087 CHEBI:77746 ! has role human metabolite [Term] id: CHEBI:29337 name: azanide namespace: chebi_ontology is_a: CHEBI:35106 ! nitrogen hydride is_a: CHEBI:79389 ! monovalent inorganic anion relationship: is_conjugate_acid_of CHEBI:29340 ! hydridonitrate(2-) relationship: is_conjugate_base_of CHEBI:16134 ! ammonia [Term] id: CHEBI:29340 name: hydridonitrate(2-) namespace: chebi_ontology def: "A divalent inorganic anion resulting from the removal of two protons from ammonia." [] is_a: CHEBI:35106 ! nitrogen hydride is_a: CHEBI:79388 ! divalent inorganic anion relationship: is_conjugate_base_of CHEBI:29337 ! azanide [Term] id: CHEBI:29793 name: hydridodioxygen(1+) namespace: chebi_ontology xref: Gmelin:508 {source="Gmelin"} is_a: CHEBI:33693 ! oxygen hydride relationship: is_conjugate_acid_of CHEBI:15379 ! dioxygen [Term] id: CHEBI:30089 name: acetate namespace: chebi_ontology def: "A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of acetic acid." [] synonym: "acetate" EXACT [UniProt] xref: Beilstein:1901470 {source="Beilstein"} xref: CAS:71-50-1 {source="ChemIDplus", source="NIST Chemistry WebBook"} xref: DrugBank:DB03166 xref: Gmelin:1379 {source="Gmelin"} xref: KEGG:C00033 xref: MetaCyc:ACET xref: PDBeChem:ACT xref: PMID:17190852 {source="Europe PMC"} xref: PMID:22211106 {source="Europe PMC"} xref: PMID:22371380 {source="Europe PMC"} xref: Reaxys:1901470 {source="Reaxys"} xref: UM-BBD_compID:c0050 {source="UM-BBD"} xref: Wikipedia:Acetate is_a: BFO:0000004 ! independent continuant is_a: CHEBI:35757 ! monocarboxylic acid anion relationship: is_conjugate_base_of CHEBI:15366 ! acetic acid relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite relationship: RO:0000087 CHEBI:77746 ! has role human metabolite [Term] id: CHEBI:30212 name: photon namespace: chebi_ontology def: "Particle of zero charge, zero rest mass, spin quantum number 1, energy hnu and momentum hnu/c (h is the Planck constant, nu the frequency of radiation and c the speed of light), carrier of electromagnetic force." [] xref: KEGG:C00205 is_a: CHEBI:36341 ! boson [Term] id: CHEBI:3098 name: bile acid namespace: chebi_ontology def: "Any member of a group of hydroxy-5beta-cholanic acids occuring in bile, where they are present as the sodium salts of their amides with glycine or taurine. In mammals bile acids almost invariably have 5beta-configuration." [] synonym: "Bile acid" EXACT [KEGG_COMPOUND] xref: KEGG:C01558 is_a: CHEBI:138366 ! bile acids is_a: CHEBI:24663 ! hydroxy-5beta-cholanic acid [Term] id: CHEBI:32952 name: amine namespace: chebi_ontology def: "A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups." [] synonym: "Amine" EXACT [KEGG_COMPOUND] xref: KEGG:C00706 is_a: CHEBI:50047 ! organic amino compound [Term] id: CHEBI:32988 name: amide namespace: chebi_ontology def: "An amide is a derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group." [] synonym: "Amide" EXACT [KEGG_COMPOUND] xref: KEGG:C00241 is_a: CHEBI:51143 ! nitrogen molecular entity [Term] id: CHEBI:33232 name: application namespace: chebi_ontology def: "Intended use of the molecular entity or part thereof by humans." [] is_a: CHEBI:50906 ! role [Term] id: CHEBI:33233 name: fundamental particle namespace: chebi_ontology def: "A particle not known to have substructure." [] is_a: CHEBI:36342 ! subatomic particle [Term] id: CHEBI:33238 name: monoatomic entity namespace: chebi_ontology def: "A monoatomic entity is a molecular entity consisting of a single atom." [] is_a: CHEBI:33259 ! elemental molecular entity [Term] id: CHEBI:33241 name: oxoacid derivative namespace: chebi_ontology is_a: CHEBI:37577 ! heteroatomic molecular entity relationship: has_functional_parent CHEBI:24833 ! oxoacid [Term] id: CHEBI:33242 name: inorganic hydride namespace: chebi_ontology is_a: CHEBI:24835 ! inorganic molecular entity is_a: CHEBI:33692 ! hydrides [Term] id: CHEBI:33245 name: organic fundamental parent namespace: chebi_ontology def: "An organic fundamental parent is a structure used as a basis for substitutive names in organic nomenclature, containing, in addition to one or more hydrogen atoms, a single atom of an element, a number of atoms (alike or different) linked together to form an unbranched chain, a monocyclic or polycyclic ring system, or a ring assembly or ring/chain system." [] is_a: CHEBI:37175 ! organic hydride is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:33246 name: inorganic group namespace: chebi_ontology def: "Any substituent group which does not contain carbon." [] is_a: CHEBI:24433 ! group [Term] id: CHEBI:33247 name: organic group namespace: chebi_ontology def: "Any substituent group or skeleton containing carbon." [] is_a: CHEBI:24433 ! group relationship: is_substituent_group_from CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:33249 name: organyl group namespace: chebi_ontology def: "Any organic substituent group, regardless of functional type, having one free valence at a carbon atom." [] is_a: CHEBI:51447 ! organic univalent group [Term] id: CHEBI:33250 name: atom namespace: chebi_ontology def: "A chemical entity constituting the smallest component of an element having the chemical properties of the element." [] is_a: CHEBI:24431 ! chemical entity relationship: BFO:0000051 CHEBI:10545 ! has part electron relationship: BFO:0000051 CHEBI:33252 ! has part atomic nucleus [Term] id: CHEBI:33252 name: atomic nucleus namespace: chebi_ontology def: "A nucleus is the positively charged central portion of an atom, excluding the orbital electrons." [] is_a: CHEBI:36347 ! nuclear particle relationship: BFO:0000051 CHEBI:33253 ! has part nucleon [Term] id: CHEBI:33253 name: nucleon namespace: chebi_ontology def: "Heavy nuclear particle: proton or neutron." [] synonym: "nucleon" EXACT [IUPAC] is_a: CHEBI:36339 ! baryon is_a: CHEBI:36347 ! nuclear particle [Term] id: CHEBI:33256 name: primary amide namespace: chebi_ontology def: "A derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group." [] synonym: "primary amide" EXACT [IUPAC] is_a: CHEBI:32988 ! amide [Term] id: CHEBI:33259 name: elemental molecular entity namespace: chebi_ontology def: "A molecular entity all atoms of which have the same atomic number." [] is_a: CHEBI:23367 ! molecular entity [Term] id: CHEBI:33262 name: elemental oxygen namespace: chebi_ontology is_a: CHEBI:24835 ! inorganic molecular entity is_a: CHEBI:25806 ! oxygen molecular entity is_a: CHEBI:33259 ! elemental molecular entity [Term] id: CHEBI:33263 name: diatomic oxygen namespace: chebi_ontology is_a: CHEBI:33262 ! elemental oxygen [Term] id: CHEBI:33273 name: polyatomic anion namespace: chebi_ontology def: "An anion consisting of more than one atom." [] is_a: CHEBI:22563 ! anion is_a: CHEBI:36358 ! polyatomic ion [Term] id: CHEBI:33280 name: molecular messenger namespace: chebi_ontology is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:33281 name: antimicrobial agent namespace: chebi_ontology def: "A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans." [] xref: PMID:12964249 {source="Europe PMC"} xref: PMID:22117953 {source="Europe PMC"} xref: PMID:22439833 {source="Europe PMC"} xref: PMID:22849268 {source="Europe PMC"} xref: PMID:22849276 {source="Europe PMC"} xref: PMID:22958833 {source="Europe PMC"} is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:33284 name: nutrient namespace: chebi_ontology def: "A nutrient is a food component that an organism uses to survive and grow." [] is_a: CHEBI:78295 ! food component [Term] id: CHEBI:33285 name: heteroorganic entity namespace: chebi_ontology def: "A heteroorganic entity is an organic molecular entity in which carbon atoms or organic groups are bonded directly to one or more heteroatoms." [] is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:33286 name: agrochemical namespace: chebi_ontology def: "An agrochemical is a substance that is used in agriculture or horticulture." [] xref: Wikipedia:Agrochemical is_a: CHEBI:33232 ! application [Term] id: CHEBI:33287 name: fertilizer namespace: chebi_ontology def: "A fertilizer is any substance that is added to soil or water to assist the growth of plants." [] is_a: CHEBI:33286 ! agrochemical [Term] id: CHEBI:33296 name: alkali metal molecular entity namespace: chebi_ontology def: "A molecular entity containing one or more atoms of an alkali metal." [] is_a: CHEBI:33674 ! s-block molecular entity relationship: BFO:0000051 CHEBI:22314 ! has part alkali metal atom [Term] id: CHEBI:33300 name: pnictogen namespace: chebi_ontology def: "Any p-block element atom that is in group 15 of the periodic table: nitrogen, phosphorus, arsenic, antimony and bismuth." [] is_a: CHEBI:33560 ! p-block element atom [Term] id: CHEBI:33302 name: pnictogen molecular entity namespace: chebi_ontology def: "A p-block molecular entity containing any pnictogen." [] synonym: "pnictogen molecular entity" EXACT [ChEBI] is_a: CHEBI:33675 ! p-block molecular entity relationship: BFO:0000051 CHEBI:33300 ! has part pnictogen [Term] id: CHEBI:33303 name: chalcogen namespace: chebi_ontology def: "Any p-block element belonging to the group 16 family of the periodic table." [] xref: PMID:17084588 {source="Europe PMC"} is_a: CHEBI:33560 ! p-block element atom [Term] id: CHEBI:33304 name: chalcogen molecular entity namespace: chebi_ontology def: "Any p-block molecular entity containing a chalcogen." [] synonym: "chalcogen molecular entity" EXACT [ChEBI] is_a: CHEBI:33675 ! p-block molecular entity relationship: BFO:0000051 CHEBI:33303 ! has part chalcogen [Term] id: CHEBI:33306 name: carbon group element atom namespace: chebi_ontology is_a: CHEBI:33560 ! p-block element atom [Term] id: CHEBI:33308 name: carboxylic ester namespace: chebi_ontology def: "An ester of a carboxylic acid, R(1)C(=O)OR(2), where R(1) = H or organyl and R(2) = organyl." [] synonym: "Carboxylic ester" EXACT [KEGG_COMPOUND] xref: KEGG:C02391 xref: Wikipedia:Ester is_a: CHEBI:35701 ! ester is_a: CHEBI:36586 ! carbonyl compound [Term] id: CHEBI:33318 name: main group element atom namespace: chebi_ontology def: "An atom belonging to one of the main groups (found in the s- and p- blocks) of the periodic table." [] is_a: CHEBI:33250 ! atom [Term] id: CHEBI:33402 name: sulfur oxoacid namespace: chebi_ontology is_a: CHEBI:26835 ! sulfur molecular entity is_a: CHEBI:33484 ! chalcogen oxoacid [Term] id: CHEBI:33408 name: pnictogen oxoacid namespace: chebi_ontology is_a: CHEBI:24833 ! oxoacid is_a: CHEBI:33302 ! pnictogen molecular entity relationship: RO:0000087 CHEBI:138103 ! has role inorganic acid [Term] id: CHEBI:33424 name: sulfur oxoacid derivative namespace: chebi_ontology synonym: "sulfur oxoacid derivative" EXACT [ChEBI] is_a: CHEBI:26835 ! sulfur molecular entity is_a: CHEBI:33241 ! oxoacid derivative [Term] id: CHEBI:33457 name: phosphorus oxoacid namespace: chebi_ontology def: "A pnictogen oxoacid which contains phosphorus and oxygen, at least one hydrogen atom bound to oxygen, and forms an ion by the loss of one or more protons." [] synonym: "phosphorus oxoacid" EXACT [ChEBI] is_a: CHEBI:33408 ! pnictogen oxoacid is_a: CHEBI:36360 ! phosphorus oxoacids and derivatives [Term] id: CHEBI:33459 name: pnictogen oxoanion namespace: chebi_ontology synonym: "pnictogen oxoanion" EXACT [ChEBI] is_a: CHEBI:33302 ! pnictogen molecular entity is_a: CHEBI:35406 ! oxoanion [Term] id: CHEBI:33461 name: phosphorus oxoanion namespace: chebi_ontology synonym: "phosphorus oxoanion" EXACT [ChEBI] is_a: CHEBI:24834 ! inorganic anion is_a: CHEBI:26082 ! phosphorus molecular entity is_a: CHEBI:33459 ! pnictogen oxoanion [Term] id: CHEBI:33482 name: sulfur oxoanion namespace: chebi_ontology synonym: "sulfur oxoanion" EXACT [ChEBI] is_a: CHEBI:26835 ! sulfur molecular entity is_a: CHEBI:33485 ! chalcogen oxoanion [Term] id: CHEBI:33484 name: chalcogen oxoacid namespace: chebi_ontology synonym: "chalcogen oxoacid" EXACT [ChEBI] is_a: CHEBI:24833 ! oxoacid relationship: RO:0000087 CHEBI:138103 ! has role inorganic acid [Term] id: CHEBI:33485 name: chalcogen oxoanion namespace: chebi_ontology synonym: "chalcogen oxoanion" EXACT [ChEBI] is_a: CHEBI:35406 ! oxoanion [Term] id: CHEBI:33504 name: alkali metal cation namespace: chebi_ontology is_a: CHEBI:25213 ! metal cation [Term] id: CHEBI:33521 name: metal atom namespace: chebi_ontology def: "An atom of an element that exhibits typical metallic properties, being typically shiny, with high electrical and thermal conductivity." [] xref: KEGG:C00050 xref: PMID:21784043 {source="Europe PMC"} xref: Wikipedia:Metal is_a: CHEBI:33250 ! atom [Term] id: CHEBI:33558 name: alpha-amino-acid anion namespace: chebi_ontology def: "An amino-acid anion obtained by deprotonation of any alpha-amino acid." [] synonym: "alpha-amino-acid anion" EXACT [ChEBI] is_a: CHEBI:37022 ! amino-acid anion relationship: is_conjugate_base_of CHEBI:33704 ! alpha-amino acid [Term] id: CHEBI:33559 name: s-block element atom namespace: chebi_ontology is_a: CHEBI:33250 ! atom [Term] id: CHEBI:33560 name: p-block element atom namespace: chebi_ontology def: "Any main group element atom belonging to the p-block of the periodic table." [] is_a: CHEBI:33318 ! main group element atom [Term] id: CHEBI:33566 name: catechols namespace: chebi_ontology def: "Any compound containing an o-diphenol component." [] xref: KEGG:C15571 is_a: CHEBI:33570 ! benzenediols [Term] id: CHEBI:33567 name: catecholamine namespace: chebi_ontology def: "4-(2-Aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution." [] synonym: "Catecholamine" EXACT [KEGG_COMPOUND] xref: KEGG:C02012 is_a: CHEBI:25375 ! monoamine molecular messenger is_a: CHEBI:33566 ! catechols [Term] id: CHEBI:33569 name: noradrenaline namespace: chebi_ontology def: "A catecholamine in which C-1 of the aminoethyl side-chain is hydroxy-substituted." [] xref: Beilstein:2210994 {source="Beilstein"} xref: CAS:138-65-8 {source="ChemIDplus", source="NIST Chemistry WebBook"} xref: Gmelin:863925 {source="Gmelin"} xref: LINCS:LSM-5181 is_a: CHEBI:33567 ! catecholamine relationship: is_conjugate_base_of CHEBI:166902 ! noradrenaline(1+) relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite [Term] id: CHEBI:33570 name: benzenediols namespace: chebi_ontology is_a: CHEBI:33853 ! phenols [Term] id: CHEBI:33571 name: (S)-noradrenaline namespace: chebi_ontology def: "The S-enantiomer of noradrenaline." [] xref: Beilstein:2937999 {source="Beilstein"} xref: LINCS:LSM-37072 xref: Reaxys:2937999 {source="Reaxys"} is_a: CHEBI:33569 ! noradrenaline relationship: is_enantiomer_of CHEBI:18357 ! (R)-noradrenaline [Term] id: CHEBI:33575 name: carboxylic acid namespace: chebi_ontology def: "A carbon oxoacid acid carrying at least one -C(=O)OH group and having the structure RC(=O)OH, where R is any any monovalent functional group. Carboxylic acids are the most common type of organic acid." [] xref: PMID:17147560 {source="Europe PMC"} xref: PMID:18433345 {source="Europe PMC"} xref: Wikipedia:Carboxylic_acid is_a: CHEBI:35605 ! carbon oxoacid is_a: CHEBI:36586 ! carbonyl compound is_a: CHEBI:64709 ! organic acid relationship: BFO:0000051 CHEBI:46883 ! has part carboxy group relationship: is_conjugate_acid_of CHEBI:29067 ! carboxylic acid anion [Term] id: CHEBI:33579 name: main group molecular entity namespace: chebi_ontology def: "A molecular entity containing one or more atoms from any of groups 1, 2, 13, 14, 15, 16, 17, and 18 of the periodic table." [] is_a: CHEBI:23367 ! molecular entity relationship: BFO:0000051 CHEBI:33318 ! has part main group element atom [Term] id: CHEBI:33582 name: carbon group molecular entity namespace: chebi_ontology synonym: "carbon group molecular entity" EXACT [ChEBI] is_a: CHEBI:33675 ! p-block molecular entity relationship: BFO:0000051 CHEBI:33306 ! has part carbon group element atom [Term] id: CHEBI:33595 name: cyclic compound namespace: chebi_ontology def: "Any molecule that consists of a series of atoms joined together to form a ring." [] xref: Wikipedia:Cyclic_compound is_a: CHEBI:25367 ! molecule [Term] id: CHEBI:33608 name: hydrogen molecular entity namespace: chebi_ontology is_a: CHEBI:33674 ! s-block molecular entity relationship: BFO:0000051 CHEBI:49637 ! has part hydrogen atom [Term] id: CHEBI:33635 name: polycyclic compound namespace: chebi_ontology is_a: CHEBI:33595 ! cyclic compound [Term] id: CHEBI:33636 name: bicyclic compound namespace: chebi_ontology def: "A molecule that features two fused rings." [] is_a: CHEBI:33595 ! cyclic compound [Term] id: CHEBI:33655 name: aromatic compound namespace: chebi_ontology def: "A cyclically conjugated molecular entity with a stability (due to delocalization) significantly greater than that of a hypothetical localized structure (e.g. Kekule structure) is said to possess aromatic character." [] is_a: CHEBI:33595 ! cyclic compound [Term] id: CHEBI:33659 name: organic aromatic compound namespace: chebi_ontology is_a: CHEBI:33655 ! aromatic compound is_a: CHEBI:33832 ! organic cyclic compound [Term] id: CHEBI:33671 name: heteropolycyclic compound namespace: chebi_ontology def: "A polycyclic compound in which at least one of the rings contains at least one non-carbon atom." [] is_a: CHEBI:33635 ! polycyclic compound is_a: CHEBI:5686 ! heterocyclic compound [Term] id: CHEBI:33672 name: heterobicyclic compound namespace: chebi_ontology def: "A bicyclic compound in which at least one of the rings contains at least one skeletal heteroatom." [] is_a: CHEBI:33636 ! bicyclic compound is_a: CHEBI:5686 ! heterocyclic compound [Term] id: CHEBI:33674 name: s-block molecular entity namespace: chebi_ontology def: "An s-block molecular entity is a molecular entity containing one or more atoms of an s-block element." [] synonym: "s-block molecular entity" EXACT [ChEBI] is_a: CHEBI:33579 ! main group molecular entity relationship: BFO:0000051 CHEBI:33559 ! has part s-block element atom [Term] id: CHEBI:33675 name: p-block molecular entity namespace: chebi_ontology def: "A main group molecular entity that contains one or more atoms of a p-block element." [] is_a: CHEBI:33579 ! main group molecular entity relationship: BFO:0000051 CHEBI:33560 ! has part p-block element atom [Term] id: CHEBI:33692 name: hydrides namespace: chebi_ontology def: "Hydrides are chemical compounds of hydrogen with other chemical elements." [] is_a: CHEBI:33608 ! hydrogen molecular entity is_a: CHEBI:37577 ! heteroatomic molecular entity [Term] id: CHEBI:33693 name: oxygen hydride namespace: chebi_ontology synonym: "oxygen hydride" EXACT [ChEBI] is_a: CHEBI:36902 ! chalcogen hydride [Term] id: CHEBI:33694 name: biomacromolecule namespace: chebi_ontology def: "A macromolecule formed by a living organism." [] is_a: CHEBI:33839 ! macromolecule is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:33695 name: information biomacromolecule namespace: chebi_ontology is_a: CHEBI:33694 ! biomacromolecule [Term] id: CHEBI:33696 name: nucleic acid namespace: chebi_ontology def: "A macromolecule made up of nucleotide units and hydrolysable into certain pyrimidine or purine bases (usually adenine, cytosine, guanine, thymine, uracil), D-ribose or 2-deoxy-D-ribose and phosphoric acid." [] is_a: CHEBI:15986 ! polynucleotide relationship: BFO:0000051 CHEBI:33791 ! has part canonical nucleoside residue relationship: BFO:0000051 CHEBI:50297 ! has part canonical nucleotide residue [Term] id: CHEBI:33697 name: ribonucleic acid namespace: chebi_ontology def: "High molecular weight, linear polymers, composed of nucleotides containing ribose and linked by phosphodiester bonds; RNA is central to the synthesis of proteins." [] synonym: "ribonucleic acid" EXACT [IUPAC] xref: CAS:63231-63-0 {source="ChemIDplus"} is_a: CHEBI:33696 ! nucleic acid relationship: BFO:0000051 CHEBI:33792 ! has part canonical ribonucleoside residue relationship: BFO:0000051 CHEBI:50299 ! has part canonical ribonucleotide residue [Term] id: CHEBI:33700 name: proteinogenic amino-acid residue namespace: chebi_ontology is_a: CHEBI:33710 ! alpha-amino-acid residue [Term] id: CHEBI:33702 name: polyatomic cation namespace: chebi_ontology def: "A cation consisting of more than one atom." [] is_a: CHEBI:36358 ! polyatomic ion is_a: CHEBI:36916 ! cation [Term] id: CHEBI:33704 name: alpha-amino acid namespace: chebi_ontology def: "An amino acid in which the amino group is located on the carbon atom at the position alpha to the carboxy group." [] xref: KEGG:C00045 xref: KEGG:C05167 is_a: CHEBI:33709 ! amino acid relationship: is_conjugate_acid_of CHEBI:33558 ! alpha-amino-acid anion relationship: is_tautomer_of CHEBI:78608 ! alpha-amino acid zwitterion [Term] id: CHEBI:33708 name: amino-acid residue namespace: chebi_ontology namespace: protein def: "When two or more amino acids combine to form a peptide, the elements of water are removed, and what remains of each amino acid is called an amino-acid residue." [] is_a: CHEBI:33247 ! organic group relationship: is_substituent_group_from CHEBI:33709 ! amino acid [Term] id: CHEBI:33709 name: amino acid namespace: chebi_ontology def: "A carboxylic acid containing one or more amino groups." [] xref: Wikipedia:Amino_acid is_a: CHEBI:33575 ! carboxylic acid is_a: CHEBI:50047 ! organic amino compound relationship: is_conjugate_acid_of CHEBI:37022 ! amino-acid anion [Term] id: CHEBI:33710 name: alpha-amino-acid residue namespace: chebi_ontology is_a: CHEBI:33708 ! amino-acid residue relationship: is_substituent_group_from CHEBI:33704 ! alpha-amino acid [Term] id: CHEBI:33720 name: carbohydrate acid namespace: chebi_ontology synonym: "carbohydrate acid" EXACT [ChEBI] is_a: CHEBI:16646 ! carbohydrate is_a: CHEBI:33575 ! carboxylic acid relationship: is_conjugate_acid_of CHEBI:33721 ! carbohydrate acid anion [Term] id: CHEBI:33721 name: carbohydrate acid anion namespace: chebi_ontology synonym: "carbohydrate acid anion" EXACT [ChEBI] is_a: CHEBI:29067 ! carboxylic acid anion relationship: is_conjugate_base_of CHEBI:33720 ! carbohydrate acid [Term] id: CHEBI:33791 name: canonical nucleoside residue namespace: chebi_ontology is_a: CHEBI:50320 ! nucleoside residue [Term] id: CHEBI:33792 name: canonical ribonucleoside residue namespace: chebi_ontology is_a: CHEBI:33791 ! canonical nucleoside residue [Term] id: CHEBI:33793 name: canonical deoxyribonucleoside residue namespace: chebi_ontology is_a: CHEBI:33791 ! canonical nucleoside residue [Term] id: CHEBI:33822 name: organic hydroxy compound namespace: chebi_ontology def: "An organic compound having at least one hydroxy group attached to a carbon atom." [] is_a: CHEBI:24651 ! hydroxides is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:33832 name: organic cyclic compound namespace: chebi_ontology def: "Any organic molecule that consists of atoms connected in the form of a ring." [] is_a: CHEBI:33595 ! cyclic compound is_a: CHEBI:72695 ! organic molecule [Term] id: CHEBI:33833 name: heteroarene namespace: chebi_ontology def: "A heterocyclic compound formally derived from an arene by replacement of one or more methine (-C=) and/or vinylene (-CH=CH-) groups by trivalent or divalent heteroatoms, respectively, in such a way as to maintain the continuous pi-electron system characteristic of aromatic systems and a number of out-of-plane pi-electrons corresponding to the Hueckel rule (4n+2)." [] is_a: CHEBI:24532 ! organic heterocyclic compound is_a: CHEBI:33659 ! organic aromatic compound [Term] id: CHEBI:33837 name: conjugated protein namespace: chebi_ontology def: "Conjugated protein is a protein that contains a non-peptide component, usually in stoichiometric proportion." [] xref: COMe:PRX000001 is_a: CHEBI:36080 ! protein [Term] id: CHEBI:33839 name: macromolecule namespace: chebi_ontology def: "A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [] xref: Wikipedia:Macromolecule is_a: CHEBI:36357 ! polyatomic entity [Term] id: CHEBI:33853 name: phenols namespace: chebi_ontology def: "Organic aromatic compounds having one or more hydroxy groups attached to a benzene or other arene ring." [] xref: KEGG:C15584 xref: MetaCyc:Phenols xref: Wikipedia:Phenols is_a: CHEBI:33659 ! organic aromatic compound is_a: CHEBI:33822 ! organic hydroxy compound [Term] id: CHEBI:33893 name: reagent namespace: chebi_ontology def: "A substance used in a chemical reaction to detect, measure, examine, or produce other substances." [] is_a: CHEBI:33232 ! application [Term] id: CHEBI:33917 name: aldohexose namespace: chebi_ontology def: "A hexose with a (potential) aldehyde group at one end." [] synonym: "aldohexose" EXACT [ChEBI] is_a: CHEBI:15693 ! aldose is_a: CHEBI:18133 ! hexose [Term] id: CHEBI:33937 name: macronutrient namespace: chebi_ontology def: "Any nutrient required in large quantities by organisms throughout their life in order to orchestrate a range of physiological functions. Macronutrients are usually chemical elements (carbon, hydrogen, nitrogen, oxygen, phosphorus and sulfur) that humans consume in the largest quantities. Calcium, sodium, magnesium and potassium are sometimes included as macronutrients because they are required in relatively large quantities compared with other vitamins and minerals." [] is_a: CHEBI:33284 ! nutrient [Term] id: CHEBI:350546 name: serotonin(1+) namespace: chebi_ontology def: "An ammonium ion that is the conjugate acid of serotonin; major species at pH 7.3." [] is_a: BFO:0000004 ! independent continuant is_a: CHEBI:35274 ! ammonium ion derivative relationship: is_conjugate_acid_of CHEBI:28790 ! serotonin relationship: RO:0000087 CHEBI:77746 ! has role human metabolite [Term] id: CHEBI:35106 name: nitrogen hydride namespace: chebi_ontology is_a: CHEBI:35881 ! pnictogen hydride is_a: CHEBI:51143 ! nitrogen molecular entity [Term] id: CHEBI:35107 name: azane namespace: chebi_ontology def: "Saturated acyclic nitrogen hydrides having the general formula NnHn+2." [] is_a: CHEBI:35106 ! nitrogen hydride [Term] id: CHEBI:35222 name: inhibitor namespace: chebi_ontology def: "A substance that diminishes the rate of a chemical reaction." [] is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:35223 name: catalyst namespace: chebi_ontology def: "A substance that increases the rate of a reaction without modifying the overall standard Gibbs energy change in the reaction." [] is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:35238 name: amino acid zwitterion namespace: chebi_ontology def: "The zwitterionic form of an amino acid having a negatively charged carboxyl group and a positively charged amino group." [] synonym: "amino acid zwitterion" EXACT [ChEBI] is_a: CHEBI:27369 ! zwitterion [Term] id: CHEBI:35267 name: quaternary ammonium ion namespace: chebi_ontology def: "A derivative of ammonium, NH4(+), in which all four of the hydrogens bonded to nitrogen have been replaced with univalent (usually organyl) groups." [] xref: KEGG:C06703 is_a: CHEBI:25697 ! organic cation is_a: CHEBI:35274 ! ammonium ion derivative [Term] id: CHEBI:35274 name: ammonium ion derivative namespace: chebi_ontology def: "A derivative of ammonium, NH4(+), in which one (or more) of the hydrogens bonded to the nitrogen have been replaced with univalent organyl groups. The substituting carbon of the organyl group must not itself be directly attached to a heteroatom (thereby excluding protonated amides, hemiaminals, etc)." [] is_a: CHEBI:33702 ! polyatomic cation is_a: CHEBI:51143 ! nitrogen molecular entity relationship: has_parent_hydride CHEBI:28938 ! ammonium [Term] id: CHEBI:35287 name: acylcholine namespace: chebi_ontology def: "A choline ester formed from choline and a carboxylic acid." [] xref: KEGG:C01777 is_a: CHEBI:35267 ! quaternary ammonium ion [Term] id: CHEBI:35341 name: steroid namespace: chebi_ontology def: "Any of naturally occurring compounds and synthetic analogues, based on the cyclopenta[a]phenanthrene carbon skeleton, partially or completely hydrogenated; there are usually methyl groups at C-10 and C-13, and often an alkyl group at C-17. By extension, one or more bond scissions, ring expansions and/or ring contractions of the skeleton may have occurred. Natural steroids are derived biogenetically from squalene which is a triterpene." [] synonym: "Steroid" EXACT [KEGG_COMPOUND] xref: KEGG:C00377 xref: MetaCyc:Steroids is_a: CHEBI:18059 ! lipid is_a: CHEBI:51958 ! organic polycyclic compound [Term] id: CHEBI:35350 name: hydroxy steroid namespace: chebi_ontology xref: KEGG:C02159 is_a: CHEBI:33822 ! organic hydroxy compound is_a: CHEBI:35341 ! steroid [Term] id: CHEBI:35352 name: organonitrogen compound namespace: chebi_ontology def: "Any heteroorganic entity containing at least one carbon-nitrogen bond." [] is_a: CHEBI:33285 ! heteroorganic entity is_a: CHEBI:51143 ! nitrogen molecular entity [Term] id: CHEBI:35381 name: monosaccharide namespace: chebi_ontology def: "Parent monosaccharides are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H-[CHOH]n-C(=O)[CHOH]m-H with three or more carbon atoms. The generic term 'monosaccharide' (as opposed to oligosaccharide or polysaccharide) denotes a single unit, without glycosidic connection to other such units. It includes aldoses, dialdoses, aldoketoses, ketoses and diketoses, as well as deoxy sugars, provided that the parent compound has a (potential) carbonyl group." [] synonym: "Monosaccharide" EXACT [KEGG_COMPOUND] xref: KEGG:C06698 is_a: CHEBI:16646 ! carbohydrate [Term] id: CHEBI:35406 name: oxoanion namespace: chebi_ontology def: "An oxoanion is an anion derived from an oxoacid by loss of hydron(s) bound to oxygen." [] synonym: "oxoanion" EXACT [ChEBI] is_a: CHEBI:25741 ! oxide is_a: CHEBI:33273 ! polyatomic anion [Term] id: CHEBI:35472 name: anti-inflammatory drug namespace: chebi_ontology def: "A substance that reduces or suppresses inflammation." [] is_a: CHEBI:23888 ! drug is_a: CHEBI:67079 ! anti-inflammatory agent [Term] id: CHEBI:35479 name: alkali metal salt namespace: chebi_ontology is_a: CHEBI:24866 ! salt is_a: CHEBI:33296 ! alkali metal molecular entity [Term] id: CHEBI:35507 name: natural product fundamental parent namespace: chebi_ontology is_a: CHEBI:33245 ! organic fundamental parent [Term] id: CHEBI:35508 name: steroid fundamental parent namespace: chebi_ontology is_a: CHEBI:35341 ! steroid is_a: CHEBI:35507 ! natural product fundamental parent [Term] id: CHEBI:35519 name: cholane namespace: chebi_ontology is_a: CHEBI:35508 ! steroid fundamental parent [Term] id: CHEBI:35524 name: sympathomimetic agent namespace: chebi_ontology def: "A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters." [] is_a: CHEBI:37962 ! adrenergic agent [Term] id: CHEBI:35554 name: cardiovascular drug namespace: chebi_ontology def: "A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume." [] is_a: CHEBI:23888 ! drug [Term] id: CHEBI:35569 name: alpha-adrenergic agonist namespace: chebi_ontology def: "An agent that selectively binds to and activates alpha-adrenergic receptors." [] is_a: CHEBI:37886 ! adrenergic agonist is_a: CHEBI:48539 ! alpha-adrenergic drug [Term] id: CHEBI:35604 name: carbon oxoanion namespace: chebi_ontology def: "A negative ion consisting solely of carbon and oxygen atoms, and therefore having the general formula CxOy(n-) for some integers x, y and n." [] synonym: "carbon oxoanion" EXACT [ChEBI] is_a: CHEBI:25696 ! organic anion is_a: CHEBI:35406 ! oxoanion is_a: CHEBI:36963 ! organooxygen compound [Term] id: CHEBI:35605 name: carbon oxoacid namespace: chebi_ontology is_a: CHEBI:24833 ! oxoacid is_a: CHEBI:36963 ! organooxygen compound [Term] id: CHEBI:35620 name: vasodilator agent namespace: chebi_ontology def: "A drug used to cause dilation of the blood vessels." [] is_a: CHEBI:35554 ! cardiovascular drug [Term] id: CHEBI:35692 name: dicarboxylic acid namespace: chebi_ontology def: "Any carboxylic acid containing two carboxy groups." [] synonym: "Dicarboxylic acid" EXACT [KEGG_COMPOUND] xref: KEGG:C02028 is_a: CHEBI:131927 ! dicarboxylic acids and O-substituted derivatives is_a: CHEBI:33575 ! carboxylic acid relationship: is_conjugate_acid_of CHEBI:35693 ! dicarboxylic acid anion [Term] id: CHEBI:35693 name: dicarboxylic acid anion namespace: chebi_ontology synonym: "dicarboxylic acid anion" EXACT [ChEBI] is_a: CHEBI:29067 ! carboxylic acid anion relationship: is_conjugate_base_of CHEBI:35692 ! dicarboxylic acid [Term] id: CHEBI:35701 name: ester namespace: chebi_ontology def: "A compound formally derived from an oxoacid RkE(=O)l(OH)m (l > 0) and an alcohol, phenol, heteroarenol, or enol by linking with formal loss of water from an acidic hydroxy group of the former and a hydroxy group of the latter." [] synonym: "Ester" EXACT [KEGG_COMPOUND] xref: KEGG:C00287 xref: Wikipedia:Ester is_a: CHEBI:36963 ! organooxygen compound [Term] id: CHEBI:35722 name: sulfated glycosaminoglycan namespace: chebi_ontology is_a: CHEBI:18085 ! glycosaminoglycan is_a: CHEBI:35724 ! carbohydrate sulfate [Term] id: CHEBI:35724 name: carbohydrate sulfate namespace: chebi_ontology is_a: CHEBI:25704 ! organic sulfate is_a: CHEBI:26819 ! sulfuric ester is_a: CHEBI:63299 ! carbohydrate derivative [Term] id: CHEBI:35757 name: monocarboxylic acid anion namespace: chebi_ontology def: "A carboxylic acid anion formed when the carboxy group of a monocarboxylic acid is deprotonated." [] xref: KEGG:C00060 is_a: CHEBI:29067 ! carboxylic acid anion relationship: is_conjugate_base_of CHEBI:25384 ! monocarboxylic acid [Term] id: CHEBI:35780 name: phosphate ion namespace: chebi_ontology def: "A phosphorus oxoanion that is the conjugate base of phosphoric acid." [] is_a: BFO:0000004 ! independent continuant is_a: CHEBI:33461 ! phosphorus oxoanion relationship: is_conjugate_base_of CHEBI:26078 ! phosphoric acid relationship: RO:0000087 CHEBI:77746 ! has role human metabolite [Term] id: CHEBI:35881 name: pnictogen hydride namespace: chebi_ontology synonym: "pnictogen hydride" EXACT [ChEBI] is_a: CHEBI:33242 ! inorganic hydride is_a: CHEBI:33302 ! pnictogen molecular entity [Term] id: CHEBI:35942 name: neurotransmitter agent namespace: chebi_ontology def: "A substance used for its pharmacological action on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function." [] is_a: CHEBI:23888 ! drug is_a: CHEBI:52210 ! pharmacological role [Term] id: CHEBI:36078 name: cholanoid namespace: chebi_ontology xref: LIPID_MAPS_class:LMST04 {source="LIPID MAPS"} is_a: CHEBI:35341 ! steroid relationship: has_parent_hydride CHEBI:35519 ! cholane [Term] id: CHEBI:36080 name: protein namespace: chebi_ontology def: "A biological macromolecule minimally consisting of one polypeptide chain synthesized at the ribosome." [] is_a: CHEBI:33695 ! information biomacromolecule relationship: BFO:0000051 CHEBI:16541 ! has part protein polypeptide chain [Term] id: CHEBI:36235 name: bile acid anion namespace: chebi_ontology is_a: CHEBI:35757 ! monocarboxylic acid anion is_a: CHEBI:50160 ! steroid acid anion [Term] id: CHEBI:36237 name: cholanic acid namespace: chebi_ontology def: "A steroid acid that consists of cholane having a carboxy group in place of the methyl group at position 24." [] xref: CAS:25312-65-6 {source="ChemIDplus"} xref: Patent:JP2008069152 xref: Reaxys:13246008 {source="Reaxys"} is_a: CHEBI:36278 ! cholanic acids [Term] id: CHEBI:36238 name: 5beta-cholanic acid namespace: chebi_ontology synonym: "5beta-cholanic acid" EXACT [ChemIDplus] xref: Beilstein:3214794 {source="Beilstein"} xref: CAS:546-18-9 {source="ChemIDplus"} xref: LIPID_MAPS_instance:LMST04010441 {source="LIPID MAPS"} is_a: CHEBI:36237 ! cholanic acid is_a: CHEBI:36248 ! 5beta-cholanic acids [Term] id: CHEBI:36248 name: 5beta-cholanic acids namespace: chebi_ontology def: "Members of the class of cholanic acids based on a 5beta-cholane skeleton." [] is_a: CHEBI:136889 ! 5beta steroid is_a: CHEBI:36278 ! cholanic acids relationship: has_parent_hydride CHEBI:20664 ! 5beta-cholane [Term] id: CHEBI:36277 name: bile acid salt namespace: chebi_ontology def: "A salt of a bile acid." [] is_a: CHEBI:24868 ! organic salt is_a: CHEBI:36078 ! cholanoid [Term] id: CHEBI:36278 name: cholanic acids namespace: chebi_ontology is_a: CHEBI:36078 ! cholanoid is_a: CHEBI:47891 ! steroid acid [Term] id: CHEBI:36338 name: lepton namespace: chebi_ontology def: "Lepton is a fermion that does not experience the strong force (strong interaction). The term is derived from the Greek lambdaepsilonpitauomicronsigma (small, thin)." [] is_a: CHEBI:33233 ! fundamental particle is_a: CHEBI:36340 ! fermion [Term] id: CHEBI:36339 name: baryon namespace: chebi_ontology def: "Baryon is a fermion that does experience the strong force (strong interaction). The term is derived from the Greek betaalpharhoupsilonsigma (heavy)." [] is_a: CHEBI:36340 ! fermion is_a: CHEBI:36344 ! hadron [Term] id: CHEBI:36340 name: fermion namespace: chebi_ontology def: "Particle of half-integer spin quantum number following Fermi-Dirac statistics. Fermions are named after Enrico Fermi." [] is_a: CHEBI:36342 ! subatomic particle [Term] id: CHEBI:36341 name: boson namespace: chebi_ontology def: "Particle of integer spin quantum number following Bose-Einstein statistics. Bosons are named after Satyendra Nath Bose." [] is_a: CHEBI:36342 ! subatomic particle [Term] id: CHEBI:36342 name: subatomic particle namespace: chebi_ontology def: "A particle smaller than an atom." [] xref: Wikipedia:Subatomic_particle [Term] id: CHEBI:36343 name: composite particle namespace: chebi_ontology def: "A subatomic particle known to have substructure (i.e. consisting of smaller particles)." [] is_a: CHEBI:36342 ! subatomic particle [Term] id: CHEBI:36344 name: hadron namespace: chebi_ontology def: "Hadron is a subatomic particle which experiences the strong force." [] is_a: CHEBI:36343 ! composite particle [Term] id: CHEBI:36347 name: nuclear particle namespace: chebi_ontology def: "A nucleus or any of its constituents in any of their energy states." [] is_a: CHEBI:36342 ! subatomic particle [Term] id: CHEBI:36357 name: polyatomic entity namespace: chebi_ontology def: "Any molecular entity consisting of more than one atom." [] is_a: CHEBI:23367 ! molecular entity relationship: BFO:0000051 CHEBI:24433 ! has part group [Term] id: CHEBI:36358 name: polyatomic ion namespace: chebi_ontology def: "An ion consisting of more than one atom." [] is_a: CHEBI:24870 ! ion is_a: CHEBI:36357 ! polyatomic entity [Term] id: CHEBI:36359 name: phosphorus oxoacid derivative namespace: chebi_ontology synonym: "phosphorus oxoacid derivative" EXACT [ChEBI] is_a: CHEBI:33241 ! oxoacid derivative is_a: CHEBI:36360 ! phosphorus oxoacids and derivatives relationship: has_functional_parent CHEBI:33457 ! phosphorus oxoacid [Term] id: CHEBI:36360 name: phosphorus oxoacids and derivatives namespace: chebi_ontology is_a: CHEBI:26082 ! phosphorus molecular entity [Term] id: CHEBI:36586 name: carbonyl compound namespace: chebi_ontology def: "Any compound containing the carbonyl group, C=O. The term is commonly used in the restricted sense of aldehydes and ketones, although it actually includes carboxylic acids and derivatives." [] is_a: CHEBI:36587 ! organic oxo compound is_a: CHEBI:36963 ! organooxygen compound relationship: BFO:0000051 CHEBI:23019 ! has part carbonyl group [Term] id: CHEBI:36587 name: organic oxo compound namespace: chebi_ontology def: "Organic compounds containing an oxygen atom, =O, doubly bonded to carbon or another element." [] is_a: CHEBI:72695 ! organic molecule relationship: BFO:0000051 CHEBI:46629 ! has part oxo group [Term] id: CHEBI:36735 name: biladienes namespace: chebi_ontology def: "Compounds based on a biladiene skeleton." [] is_a: CHEBI:25046 ! linear tetrapyrrole [Term] id: CHEBI:36902 name: chalcogen hydride namespace: chebi_ontology synonym: "chalcogen hydride" EXACT [ChEBI] is_a: CHEBI:33242 ! inorganic hydride is_a: CHEBI:33304 ! chalcogen molecular entity [Term] id: CHEBI:36914 name: inorganic ion namespace: chebi_ontology is_a: CHEBI:24835 ! inorganic molecular entity is_a: CHEBI:24870 ! ion [Term] id: CHEBI:36915 name: inorganic cation namespace: chebi_ontology is_a: CHEBI:36914 ! inorganic ion is_a: CHEBI:36916 ! cation [Term] id: CHEBI:36916 name: cation namespace: chebi_ontology def: "A monoatomic or polyatomic species having one or more elementary charges of the proton." [] synonym: "Cation" EXACT [KEGG_COMPOUND] synonym: "cation" EXACT [ChEBI] xref: KEGG:C01373 is_a: CHEBI:24870 ! ion [Term] id: CHEBI:36961 name: chalcocarbonic acid namespace: chebi_ontology synonym: "chalcocarbonic acid" EXACT [ChEBI] is_a: CHEBI:36962 ! organochalcogen compound [Term] id: CHEBI:36962 name: organochalcogen compound namespace: chebi_ontology def: "An organochalcogen compound is a compound containing at least one carbon-chalcogen bond." [] synonym: "organochalcogen compound" EXACT [ChEBI] is_a: CHEBI:33285 ! heteroorganic entity is_a: CHEBI:33304 ! chalcogen molecular entity [Term] id: CHEBI:36963 name: organooxygen compound namespace: chebi_ontology def: "An organochalcogen compound containing at least one carbon-oxygen bond." [] synonym: "organooxygen compound" EXACT [ChEBI] xref: PMID:17586126 {source="Europe PMC"} is_a: CHEBI:25806 ! oxygen molecular entity is_a: CHEBI:36962 ! organochalcogen compound [Term] id: CHEBI:37022 name: amino-acid anion namespace: chebi_ontology synonym: "amino-acid anion" EXACT [ChEBI] is_a: CHEBI:29067 ! carboxylic acid anion is_a: CHEBI:35352 ! organonitrogen compound relationship: is_conjugate_base_of CHEBI:33709 ! amino acid [Term] id: CHEBI:37163 name: glucan namespace: chebi_ontology def: "A polysaccharide composed of glucose residues." [] synonym: "Glucan" EXACT [KEGG_COMPOUND] xref: CAS:9037-91-6 {source="ChemIDplus"} xref: KEGG:C01379 is_a: CHEBI:37164 ! homopolysaccharide [Term] id: CHEBI:37164 name: homopolysaccharide namespace: chebi_ontology def: "Glycans composed of a single type of monosaccharide residue. They are named by replacing the ending '-ose' of the sugar by '-an'." [] is_a: CHEBI:18154 ! polysaccharide [Term] id: CHEBI:37175 name: organic hydride namespace: chebi_ontology is_a: CHEBI:33692 ! hydrides [Term] id: CHEBI:37176 name: mononuclear parent hydride namespace: chebi_ontology is_a: CHEBI:33692 ! hydrides [Term] id: CHEBI:37246 name: elemental sodium namespace: chebi_ontology is_a: CHEBI:26712 ! sodium molecular entity [Term] id: CHEBI:37395 name: mucopolysaccharide namespace: chebi_ontology def: "Any of the group of polysaccharides composed of alternating units from uronic acids and glycosamines, and commonly partially esterified with sulfuric acid." [] synonym: "Mucopolysaccharide" EXACT [KEGG_COMPOUND] xref: KEGG:C05114 is_a: CHEBI:18085 ! glycosaminoglycan [Term] id: CHEBI:37527 name: acid namespace: chebi_ontology def: "An acid is a molecular entity capable of donating a hydron (Bronsted acid) or capable of forming a covalent bond with an electron pair (Lewis acid)." [] synonym: "Acid" EXACT [KEGG_COMPOUND] xref: KEGG:C00174 is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:37577 name: heteroatomic molecular entity namespace: chebi_ontology def: "A molecular entity consisting of two or more chemical elements." [] is_a: CHEBI:36357 ! polyatomic entity [Term] id: CHEBI:37622 name: carboxamide namespace: chebi_ontology def: "An amide of a carboxylic acid, having the structure RC(=O)NR2. The term is used as a suffix in systematic name formation to denote the -C(=O)NH2 group including its carbon atom." [] is_a: CHEBI:33256 ! primary amide is_a: CHEBI:35352 ! organonitrogen compound is_a: CHEBI:36963 ! organooxygen compound relationship: BFO:0000051 CHEBI:23004 ! has part carbamoyl group [Term] id: CHEBI:37826 name: sulfuric acid derivative namespace: chebi_ontology synonym: "sulfuric acid derivative" EXACT [ChEBI] is_a: CHEBI:33424 ! sulfur oxoacid derivative relationship: has_functional_parent CHEBI:26836 ! sulfuric acid [Term] id: CHEBI:37838 name: carboacyl group namespace: chebi_ontology def: "A carboacyl group is a group formed by loss of at least one OH from the carboxy group of a carboxylic acid." [] is_a: CHEBI:22221 ! acyl group relationship: is_substituent_group_from CHEBI:33575 ! carboxylic acid [Term] id: CHEBI:37886 name: adrenergic agonist namespace: chebi_ontology def: "An agent that selectively binds to and activates adrenergic receptors." [] is_a: CHEBI:37962 ! adrenergic agent [Term] id: CHEBI:37962 name: adrenergic agent namespace: chebi_ontology def: "Any agent that acts on an adrenergic receptor or affects the life cycle of an adrenergic transmitter." [] is_a: CHEBI:35942 ! neurotransmitter agent [Term] id: CHEBI:38077 name: polypyrrole namespace: chebi_ontology def: "A compound composed of two or more pyrrole units." [] xref: Beilstein:8538310 {source="Beilstein"} is_a: CHEBI:38101 ! organonitrogen heterocyclic compound [Term] id: CHEBI:38101 name: organonitrogen heterocyclic compound namespace: chebi_ontology def: "Any organonitrogen compound containing a cyclic component with nitrogen and at least one other element as ring member atoms." [] is_a: CHEBI:24532 ! organic heterocyclic compound is_a: CHEBI:35352 ! organonitrogen compound [Term] id: CHEBI:38166 name: organic heteropolycyclic compound namespace: chebi_ontology is_a: CHEBI:24532 ! organic heterocyclic compound is_a: CHEBI:33671 ! heteropolycyclic compound [Term] id: CHEBI:38180 name: polycyclic heteroarene namespace: chebi_ontology is_a: CHEBI:33833 ! heteroarene [Term] id: CHEBI:38323 name: cholinergic drug namespace: chebi_ontology def: "Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons." [] is_a: CHEBI:35942 ! neurotransmitter agent [Term] id: CHEBI:38324 name: cholinergic agonist namespace: chebi_ontology def: "Any drug that binds to and activates cholinergic receptors." [] is_a: CHEBI:38323 ! cholinergic drug [Term] id: CHEBI:38325 name: muscarinic agonist namespace: chebi_ontology def: "Any drug that binds to and activates a muscarinic cholinergic receptor." [] is_a: CHEBI:38324 ! cholinergic agonist [Term] id: CHEBI:38631 name: aminoalkylindole namespace: chebi_ontology is_a: CHEBI:24828 ! indoles [Term] id: CHEBI:38700 name: organic sodium salt namespace: chebi_ontology synonym: "organic sodium salt" EXACT [ChEBI] is_a: CHEBI:24868 ! organic salt is_a: CHEBI:26714 ! sodium salt [Term] id: CHEBI:38716 name: carboxylic acid dianion namespace: chebi_ontology def: "Any dianion containing at least one carboxy group." [] synonym: "carboxylic acid dianion" EXACT [ChEBI] is_a: CHEBI:29067 ! carboxylic acid anion [Term] id: CHEBI:38958 name: indole alkaloid namespace: chebi_ontology def: "An alkaloid containing an indole skeleton." [] synonym: "Indole alkaloid" EXACT [KEGG_COMPOUND] xref: KEGG:C06073 xref: Wikipedia:Indole_alkaloid is_a: CHEBI:22315 ! alkaloid relationship: BFO:0000051 CHEBI:73398 ! has part indole skeleton [Term] id: CHEBI:39141 name: Bronsted acid namespace: chebi_ontology def: "A molecular entity capable of donating a hydron to an acceptor (Bronsted base)." [] is_a: CHEBI:17891 ! donor is_a: CHEBI:37527 ! acid [Term] id: CHEBI:39142 name: Bronsted base namespace: chebi_ontology def: "A molecular entity capable of accepting a hydron from a donor (Bronsted acid)." [] is_a: CHEBI:15339 ! acceptor is_a: CHEBI:22695 ! base [Term] id: CHEBI:39144 name: Lewis base namespace: chebi_ontology def: "A molecular entity able to provide a pair of electrons and thus capable of forming a covalent bond with an electron-pair acceptor (Lewis acid), thereby producing a Lewis adduct." [] is_a: CHEBI:17891 ! donor is_a: CHEBI:22695 ! base [Term] id: CHEBI:39745 name: dihydrogenphosphate namespace: chebi_ontology def: "A monovalent inorganic anion that consists of phosphoric acid in which one of the three OH groups has been deprotonated." [] xref: DrugBank:DB02831 xref: Gmelin:1999 {source="Gmelin"} xref: PDBeChem:2HP is_a: CHEBI:35780 ! phosphate ion is_a: CHEBI:79389 ! monovalent inorganic anion relationship: is_conjugate_acid_of CHEBI:43474 ! hydrogenphosphate [Term] id: CHEBI:41609 name: carbonate namespace: chebi_ontology synonym: "carbonate" EXACT [IUPAC] xref: Beilstein:3600898 {source="Beilstein"} xref: CAS:3812-32-6 {source="ChemIDplus"} xref: Gmelin:1559 {source="Gmelin"} xref: PDBeChem:CO3 is_a: CHEBI:35604 ! carbon oxoanion relationship: is_conjugate_base_of CHEBI:17544 ! hydrogencarbonate [Term] id: CHEBI:43176 name: hydroxy group namespace: chebi_ontology synonym: "HYDROXY GROUP" EXACT [PDBeChem] synonym: "hydroxy group" EXACT [UniProt] xref: PDBeChem:OH is_a: CHEBI:33246 ! inorganic group [Term] id: CHEBI:43474 name: hydrogenphosphate namespace: chebi_ontology def: "A phosphate ion that is the conjugate base of dihydrogenphosphate." [] xref: Gmelin:1998 {source="Gmelin"} xref: MolBase:1628 xref: PDBeChem:PI xref: PDBeChem:PO4 is_a: CHEBI:35780 ! phosphate ion is_a: CHEBI:79388 ! divalent inorganic anion relationship: is_conjugate_acid_of CHEBI:18367 ! phosphate(3-) relationship: is_conjugate_base_of CHEBI:39745 ! dihydrogenphosphate relationship: RO:0000087 CHEBI:23357 ! has role cofactor relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite [Term] id: CHEBI:45696 name: hydrogensulfate namespace: chebi_ontology synonym: "hydrogensulfate" EXACT [IUPAC] xref: Gmelin:2121 {source="Gmelin"} is_a: CHEBI:33482 ! sulfur oxoanion relationship: is_conjugate_acid_of CHEBI:16189 ! sulfate relationship: is_conjugate_base_of CHEBI:26836 ! sulfuric acid [Term] id: CHEBI:46629 name: oxo group namespace: chebi_ontology synonym: "OXO GROUP" EXACT [PDBeChem] xref: PDBeChem:O is_a: CHEBI:33246 ! inorganic group [Term] id: CHEBI:46787 name: solvent namespace: chebi_ontology def: "A liquid that can dissolve other substances (solutes) without any change in their chemical composition." [] xref: Wikipedia:Solvent is_a: CHEBI:33232 ! application is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:46883 name: carboxy group namespace: chebi_ontology synonym: "CARBOXY GROUP" EXACT [PDBeChem] xref: PDBeChem:FMT is_a: CHEBI:33249 ! organyl group [Term] id: CHEBI:47622 name: acetate ester namespace: chebi_ontology def: "Any carboxylic ester where the carboxylic acid component is acetic acid." [] xref: KEGG:C01883 xref: Wikipedia:Acetate#Esters is_a: CHEBI:33308 ! carboxylic ester relationship: has_functional_parent CHEBI:15366 ! acetic acid [Term] id: CHEBI:47891 name: steroid acid namespace: chebi_ontology def: "Any steroid substituted by at least one carboxy group." [] is_a: CHEBI:35341 ! steroid is_a: CHEBI:64709 ! organic acid relationship: is_conjugate_acid_of CHEBI:50160 ! steroid acid anion [Term] id: CHEBI:48154 name: sulfur oxide namespace: chebi_ontology is_a: CHEBI:24836 ! inorganic oxide is_a: CHEBI:26835 ! sulfur molecular entity [Term] id: CHEBI:48354 name: polar solvent namespace: chebi_ontology def: "A solvent that is composed of polar molecules. Polar solvents can dissolve ionic compounds or ionisable covalent compounds." [] is_a: CHEBI:46787 ! solvent [Term] id: CHEBI:48356 name: protic solvent namespace: chebi_ontology def: "A polar solvent that is capable of acting as a hydron (proton) donor." [] is_a: CHEBI:39141 ! Bronsted acid is_a: CHEBI:48354 ! polar solvent [Term] id: CHEBI:48539 name: alpha-adrenergic drug namespace: chebi_ontology def: "Any drug that acts on an alpha-adrenergic receptor." [] is_a: CHEBI:37962 ! adrenergic agent [Term] id: CHEBI:48705 name: agonist namespace: chebi_ontology def: "Substance which binds to cell receptors normally responding to naturally occurring substances and which produces a response of its own." [] is_a: CHEBI:52210 ! pharmacological role [Term] id: CHEBI:49637 name: hydrogen atom namespace: chebi_ontology xref: WebElements:H is_a: BFO:0000004 ! independent continuant is_a: CHEBI:24835 ! inorganic molecular entity is_a: CHEBI:25585 ! nonmetal atom is_a: CHEBI:33559 ! s-block element atom relationship: RO:0000087 CHEBI:33937 ! has role macronutrient [Term] id: CHEBI:50047 name: organic amino compound namespace: chebi_ontology def: "A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by organyl groups." [] is_a: BFO:0000004 ! independent continuant is_a: CHEBI:35352 ! organonitrogen compound relationship: has_parent_hydride CHEBI:16134 ! ammonia relationship: RO:0000087 CHEBI:39142 ! has role Bronsted base [Term] id: CHEBI:50160 name: steroid acid anion namespace: chebi_ontology def: "Any anion formed by loss of a proton from a steroid acid." [] is_a: CHEBI:29067 ! carboxylic acid anion relationship: is_conjugate_base_of CHEBI:47891 ! steroid acid [Term] id: CHEBI:50297 name: canonical nucleotide residue namespace: chebi_ontology is_a: CHEBI:50319 ! nucleotide residue [Term] id: CHEBI:50298 name: canonical deoxyribonucleotide residue namespace: chebi_ontology is_a: CHEBI:50297 ! canonical nucleotide residue [Term] id: CHEBI:50299 name: canonical ribonucleotide residue namespace: chebi_ontology is_a: CHEBI:50297 ! canonical nucleotide residue [Term] id: CHEBI:50312 name: onium compound namespace: chebi_ontology is_a: CHEBI:37577 ! heteroatomic molecular entity [Term] id: CHEBI:50313 name: onium cation namespace: chebi_ontology def: "Mononuclear cations derived by addition of a hydron to a mononuclear parent hydride of the pnictogen, chalcogen and halogen families." [] is_a: CHEBI:50312 ! onium compound [Term] id: CHEBI:50319 name: nucleotide residue namespace: chebi_ontology is_a: CHEBI:33247 ! organic group [Term] id: CHEBI:50320 name: nucleoside residue namespace: chebi_ontology is_a: CHEBI:33247 ! organic group [Term] id: CHEBI:50514 name: vasoconstrictor agent namespace: chebi_ontology def: "Drug used to cause constriction of the blood vessels." [] is_a: CHEBI:35554 ! cardiovascular drug [Term] id: CHEBI:50860 name: organic molecular entity namespace: chebi_ontology def: "Any molecular entity that contains carbon." [] is_a: CHEBI:33582 ! carbon group molecular entity relationship: BFO:0000051 CHEBI:27594 ! has part carbon atom [Term] id: CHEBI:50906 name: role namespace: chebi_ontology def: "A role is particular behaviour which a material entity may exhibit." [] is_a: PATO:0000001 ! quality [Term] id: CHEBI:50910 name: neurotoxin namespace: chebi_ontology def: "A poison that interferes with the functions of the nervous system." [] xref: Wikipedia:Neurotoxin is_a: CHEBI:52209 ! aetiopathogenetic role is_a: CHEBI:64909 ! poison [Term] id: CHEBI:50994 name: primary amino compound namespace: chebi_ontology def: "A compound formally derived from ammonia by replacing one hydrogen atom by an organyl group." [] is_a: CHEBI:50047 ! organic amino compound relationship: is_conjugate_base_of CHEBI:65296 ! primary ammonium ion [Term] id: CHEBI:51086 name: chemical role namespace: chebi_ontology def: "A role played by the molecular entity or part thereof within a chemical context." [] is_a: CHEBI:50906 ! role [Term] id: CHEBI:51143 name: nitrogen molecular entity namespace: chebi_ontology xref: KEGG:C06061 is_a: CHEBI:33302 ! pnictogen molecular entity relationship: BFO:0000051 CHEBI:25555 ! has part nitrogen atom [Term] id: CHEBI:51151 name: dipolar compound namespace: chebi_ontology def: "An organic molecule that is electrically neutral carrying a positive and a negative charge in one of its major canonical descriptions. In most dipolar compounds the charges are delocalized; however the term is also applied to species where this is not the case." [] is_a: CHEBI:72695 ! organic molecule [Term] id: CHEBI:51422 name: organodiyl group namespace: chebi_ontology def: "Any organic substituent group, regardless of functional type, having two free valences at carbon atom(s)." [] is_a: CHEBI:51446 ! organic divalent group [Term] id: CHEBI:51446 name: organic divalent group namespace: chebi_ontology is_a: CHEBI:33247 ! organic group [Term] id: CHEBI:51447 name: organic univalent group namespace: chebi_ontology is_a: CHEBI:33247 ! organic group [Term] id: CHEBI:51958 name: organic polycyclic compound namespace: chebi_ontology is_a: CHEBI:33635 ! polycyclic compound is_a: CHEBI:33832 ! organic cyclic compound [Term] id: CHEBI:52206 name: biochemical role namespace: chebi_ontology def: "A biological role played by the molecular entity or part thereof within a biochemical context." [] is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:52209 name: aetiopathogenetic role namespace: chebi_ontology def: "A role played by the molecular entity or part thereof which causes the development of a pathological process." [] is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:52210 name: pharmacological role namespace: chebi_ontology def: "A biological role which describes how a drug interacts within a biological system and how the interactions affect its medicinal properties." [] is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:52211 name: physiological role namespace: chebi_ontology is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:52217 name: pharmaceutical namespace: chebi_ontology def: "Any substance introduced into a living organism with therapeutic or diagnostic purpose." [] is_a: CHEBI:33232 ! application [Term] id: CHEBI:52845 name: cyclic organic group namespace: chebi_ontology def: "An organic group that consists of a closed ring. It may be a substituent or a skeleton." [] is_a: CHEBI:33247 ! organic group [Term] id: CHEBI:53000 name: epitope namespace: chebi_ontology def: "The biological role played by a material entity when bound by a receptor of the adaptive immune system. Specific site on an antigen to which an antibody binds." [] is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:53309 name: polyanionic macromolecule namespace: chebi_ontology def: "A polymer carrying multiple negative charges." [] is_a: CHEBI:53368 ! ionic macromolecule [Term] id: CHEBI:53368 name: ionic macromolecule namespace: chebi_ontology def: "A macromolecule containing ionic groups." [] is_a: CHEBI:33839 ! macromolecule [Term] id: CHEBI:5391 name: glucagon namespace: chebi_ontology def: "A 29-amino acid peptide hormone consisting of His, Ser, Gln, Gly, Thr, Phe, Thr, Ser, Asp, Tyr, Ser, Lys, Tyr, Leu, Asp, Ser, Arg, Arg, Ala, Gln, Asp, Phe, Val, Gln, Trp, Leu, Met, Asn and Thr residues joined in sequence." [] synonym: "Glucagon" EXACT [KEGG_COMPOUND] xref: CAS:16941-32-5 {source="ChemIDplus"} xref: CAS:9007-92-5 {source="ChemIDplus", source="KEGG COMPOUND"} xref: Drug_Central:2994 {source="DrugCentral"} xref: DrugBank:DB00040 xref: KEGG:C01501 xref: KEGG:D00116 xref: PMID:21940356 {source="Europe PMC"} xref: PMID:22014161 {source="Europe PMC"} xref: PMID:22154917 {source="Europe PMC"} xref: PMID:22166985 {source="Europe PMC"} xref: PMID:22167521 {source="Europe PMC"} xref: PMID:22214853 {source="Europe PMC"} xref: PMID:22227186 {source="Europe PMC"} xref: PMID:22286080 {source="Europe PMC"} xref: PMID:22294753 {source="Europe PMC"} xref: PMID:22318544 {source="Europe PMC"} xref: PMID:22334714 {source="Europe PMC"} xref: PMID:22399501 {source="Europe PMC"} xref: PMID:22438981 {source="Europe PMC"} xref: PMID:22454291 {source="Europe PMC"} xref: Reaxys:13191924 {source="Reaxys"} xref: Wikipedia:Glucagon is_a: CHEBI:25905 ! peptide hormone [Term] id: CHEBI:5686 name: heterocyclic compound namespace: chebi_ontology def: "A cyclic compound having as ring members atoms of at least two different elements." [] synonym: "Heterocyclic compound" EXACT [KEGG_COMPOUND] is_a: CHEBI:33595 ! cyclic compound [Term] id: CHEBI:57887 name: tryptaminium namespace: chebi_ontology def: "An ammonium ion that is the conjugate acid of tryptamine arising from protonation of the primary amino group; major species at pH 7.3." [] xref: Gmelin:533978 {source="Gmelin"} is_a: BFO:0000004 ! independent continuant is_a: CHEBI:65296 ! primary ammonium ion relationship: is_conjugate_acid_of CHEBI:16765 ! tryptamine relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite relationship: RO:0000087 CHEBI:77746 ! has role human metabolite [Term] id: CHEBI:57977 name: bilirubin(2-) namespace: chebi_ontology def: "A dicarboxylic acid dianion obtained by deprotonation of the two carboxy groups of bilirubin; major species at pH 7.3." [] xref: Beilstein:4083310 {source="Beilstein"} is_a: BFO:0000004 ! independent continuant is_a: CHEBI:28965 ! dicarboxylic acid dianion is_a: CHEBI:59252 ! linear tetrapyrrole anion relationship: is_conjugate_base_of CHEBI:16990 ! bilirubin IXalpha relationship: RO:0000087 CHEBI:77746 ! has role human metabolite [Term] id: CHEBI:58958 name: organosulfate oxoanion namespace: chebi_ontology def: "An organic anion of general formula RS(=O)2O(-) where R is an organyl group." [] is_a: CHEBI:25696 ! organic anion is_a: CHEBI:33482 ! sulfur oxoanion relationship: has_functional_parent CHEBI:16189 ! sulfate relationship: is_conjugate_base_of CHEBI:25704 ! organic sulfate [Term] id: CHEBI:59252 name: linear tetrapyrrole anion namespace: chebi_ontology def: "An organic anion arising from deprotonation of a acyclic tetrapyrrole compound." [] is_a: CHEBI:25696 ! organic anion [Term] id: CHEBI:59698 name: phosphoric acids namespace: chebi_ontology def: "Compounds containing one or more phosphoric acid units." [] is_a: CHEBI:33457 ! phosphorus oxoacid [Term] id: CHEBI:59740 name: nucleophilic reagent namespace: chebi_ontology def: "A reagent that forms a bond to its reaction partner (the electrophile) by donating both bonding electrons." [] is_a: CHEBI:33893 ! reagent is_a: CHEBI:39144 ! Lewis base [Term] id: CHEBI:59999 name: chemical substance namespace: chebi_ontology def: "A chemical substance is a portion of matter of constant composition, composed of molecular entities of the same type or of different types." [] is_a: CHEBI:24431 ! chemical entity [Term] id: CHEBI:60004 name: mixture namespace: chebi_ontology def: "A mixture is a chemical substance composed of multiple molecules, at least two of which are of a different kind." [] is_a: CHEBI:59999 ! chemical substance [Term] id: CHEBI:60027 name: polymer namespace: chebi_ontology def: "A polymer is a mixture, which is composed of macromolecules of different kinds and which may be differentiated by composition, length, degree of branching etc.." [] synonym: "Polymer" EXACT [ChEBI] xref: Wikipedia:Polymer is_a: CHEBI:60004 ! mixture relationship: BFO:0000051 CHEBI:33839 ! has part macromolecule [Term] id: CHEBI:60164 name: ionic polymer namespace: chebi_ontology def: "An ionic polymer is a polymer, composed of ionic macromolecules." [] is_a: CHEBI:60027 ! polymer relationship: BFO:0000051 CHEBI:53368 ! has part ionic macromolecule [Term] id: CHEBI:60242 name: monovalent inorganic cation namespace: chebi_ontology def: "An atom or small molecule with a positive charge that does not contain carbon in covalent linkage, with a valency of one." [] is_a: CHEBI:36915 ! inorganic cation [Term] id: CHEBI:60466 name: peptide zwitterion namespace: chebi_ontology def: "Zwitterionic form of any peptide where, in general, the amino terminus is positively charged and the carboxy terminus is negatively charged." [] is_a: CHEBI:27369 ! zwitterion relationship: is_tautomer_of CHEBI:16670 ! peptide [Term] id: CHEBI:60926 name: amino monosaccharide namespace: chebi_ontology def: "Any amino sugar that is a monosaccharide in which one alcoholic hydroxy group is replaced by an amino group." [] is_a: CHEBI:28963 ! amino sugar [Term] id: CHEBI:61120 name: nucleobase-containing molecular entity namespace: chebi_ontology def: "Any compound that has a nucleobase as a part." [] is_a: CHEBI:33833 ! heteroarene is_a: CHEBI:51143 ! nitrogen molecular entity relationship: has_functional_parent CHEBI:18282 ! nucleobase [Term] id: CHEBI:61469 name: polyanionic polymer namespace: chebi_ontology def: "A polymer, composed of polyanion macromolecules." [] is_a: CHEBI:60164 ! ionic polymer relationship: BFO:0000051 CHEBI:53309 ! has part polyanionic macromolecule [Term] id: CHEBI:63248 name: oxidising agent namespace: chebi_ontology def: "A substance that removes electrons from another reactant in a redox reaction." [] is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:63299 name: carbohydrate derivative namespace: chebi_ontology def: "Any organooxygen compound derived from a carbohydrate by replacement of one or more hydroxy group(s) by an amino group, a thiol group or similar heteroatomic groups. The term also includes derivatives of these compounds." [] is_a: CHEBI:78616 ! carbohydrates and carbohydrate derivatives relationship: has_functional_parent CHEBI:16646 ! carbohydrate [Term] id: CHEBI:63436 name: carbohydrate acid derivative namespace: chebi_ontology def: "A carbohydrate derivative that is formally obtained from a carbohydrate acid." [] is_a: CHEBI:63299 ! carbohydrate derivative relationship: has_functional_parent CHEBI:33720 ! carbohydrate acid relationship: is_conjugate_acid_of CHEBI:63551 ! carbohydrate acid derivative anion [Term] id: CHEBI:63534 name: monoamine namespace: chebi_ontology def: "An aralylamino compound which contains one amino group connected to an aromatic ring by a two-carbon chain. Monoamines are derived from aromatic amino acids like phenylalanine, tyrosine, tryptophan, and the thyroid hormones by the action of aromatic amino acid decarboxylase enzymes." [] xref: PMID:21822758 {source="Europe PMC"} xref: PMID:21993877 {source="Europe PMC"} xref: PMID:22005599 {source="Europe PMC"} xref: PMID:22082101 {source="Europe PMC"} xref: PMID:22153577 {source="Europe PMC"} xref: PMID:22213370 {source="Europe PMC"} xref: PMID:22218931 {source="Europe PMC"} xref: PMID:22342987 {source="Europe PMC"} xref: PMID:22371656 {source="Europe PMC"} is_a: CHEBI:64365 ! aralkylamino compound [Term] id: CHEBI:63551 name: carbohydrate acid derivative anion namespace: chebi_ontology def: "A carboxylic acid anion resulting from the deprotonation of the carboxy group of a carbohydrate acid derivative." [] is_a: CHEBI:29067 ! carboxylic acid anion relationship: has_functional_parent CHEBI:33721 ! carbohydrate acid anion relationship: is_conjugate_base_of CHEBI:63436 ! carbohydrate acid derivative [Term] id: CHEBI:64047 name: food additive namespace: chebi_ontology def: "Any substance which is added to food to preserve or enhance its flavour and/or appearance." [] xref: Wikipedia:Food_additive is_a: CHEBI:33232 ! application is_a: CHEBI:78295 ! food component [Term] id: CHEBI:64049 name: food acidity regulator namespace: chebi_ontology def: "A food additive that is used to change or otherwise control the acidity or alkalinity of foods. They may be acids, bases, neutralising agents or buffering agents." [] xref: Wikipedia:Acidity_regulator is_a: CHEBI:64047 ! food additive [Term] id: CHEBI:64365 name: aralkylamino compound namespace: chebi_ontology def: "An organic amino compound in which an aminoalkyl group is linked to an arene." [] is_a: CHEBI:50047 ! organic amino compound [Term] id: CHEBI:64628 name: somatostatin namespace: chebi_ontology def: "A fourteen-membered heterodetic cyclic peptide comprising the sequence Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys cyclised by a disulfide bridge between the two Cys residues at positions 3 and 14." [] xref: CAS:38916-34-6 {source="ChemIDplus", source="KEGG DRUG"} xref: Drug_Central:2997 {source="DrugCentral"} xref: HMDB:HMDB0013072 xref: KEGG:C16022 xref: KEGG:D07431 xref: LINCS:LSM-5326 xref: PMID:21922516 {source="Europe PMC"} xref: PMID:22129035 {source="Europe PMC"} xref: PMID:22147011 {source="Europe PMC"} xref: PMID:22251942 {source="Europe PMC"} xref: PMID:22483686 {source="Europe PMC"} xref: PMID:22509294 {source="Europe PMC"} xref: Reaxys:10148626 {source="Reaxys"} xref: Wikipedia:Somatostatin is_a: CHEBI:24533 ! heterodetic cyclic peptide is_a: CHEBI:25905 ! peptide hormone [Term] id: CHEBI:64708 name: one-carbon compound namespace: chebi_ontology def: "An organic molecular entity containing a single carbon atom (C1)." [] is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:64709 name: organic acid namespace: chebi_ontology def: "Any organic molecular entity that is acidic and contains carbon in covalent linkage." [] is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:64909 name: poison namespace: chebi_ontology def: "Any substance that causes disturbance to organisms by chemical reaction or other activity on the molecular scale, when a sufficient quantity is absorbed by the organism." [] xref: Wikipedia:Poison is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:65212 name: polysaccharide derivative namespace: chebi_ontology def: "A carbohydrate derivative that is any derivative of a polysaccharide." [] is_a: CHEBI:167559 ! glycan is_a: CHEBI:33694 ! biomacromolecule is_a: CHEBI:63299 ! carbohydrate derivative relationship: has_functional_parent CHEBI:18154 ! polysaccharide [Term] id: CHEBI:65255 name: food preservative namespace: chebi_ontology def: "Substances which are added to food in order to prevent decomposition caused by microbial growth or by undesirable chemical changes." [] is_a: CHEBI:64047 ! food additive [Term] id: CHEBI:65256 name: antimicrobial food preservative namespace: chebi_ontology def: "A food preservative which prevents decomposition of food by preventing the growth of fungi or bacteria. In European countries, E-numbers for permitted food preservatives are from E200 to E299, divided into sorbates (E200-209), benzoates (E210-219), sulfites (E220-229), phenols and formates (E230-239), nitrates (E240-259), acetates (E260-269), lactates (E270-279), propionates (E280-289) and others (E290-299)." [] is_a: CHEBI:33281 ! antimicrobial agent is_a: CHEBI:65255 ! food preservative [Term] id: CHEBI:65296 name: primary ammonium ion namespace: chebi_ontology def: "An ammonium ion derivative resulting from the protonation of the nitrogen atom of a primary amino compound. Major species at pH 7.3." [] is_a: CHEBI:25697 ! organic cation is_a: CHEBI:35274 ! ammonium ion derivative relationship: is_conjugate_acid_of CHEBI:50994 ! primary amino compound [Term] id: CHEBI:67079 name: anti-inflammatory agent namespace: chebi_ontology def: "Any compound that has anti-inflammatory effects." [] is_a: CHEBI:33232 ! application [Term] id: CHEBI:72587 name: (R)-noradrenaline(1+) namespace: chebi_ontology def: "An organic cation that is the conjugate acid of (R)-noradrenaline, obtained by protonation of the priamry amino group; major species at pH 7.3." [] xref: PDBeChem:E5E is_a: BFO:0000004 ! independent continuant is_a: CHEBI:166902 ! noradrenaline(1+) relationship: is_conjugate_acid_of CHEBI:18357 ! (R)-noradrenaline relationship: RO:0000087 CHEBI:77746 ! has role human metabolite [Term] id: CHEBI:72695 name: organic molecule namespace: chebi_ontology def: "Any molecule that consists of at least one carbon atom as part of the electrically neutral entity." [] is_a: CHEBI:25367 ! molecule is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:72813 name: exopolysaccharide namespace: chebi_ontology def: "A biomacromolecule composed of carbohydrate residues which is secreted by a microorganism into the surrounding environment." [] xref: MetaCyc:Exopolysaccharides xref: PMID:11160795 {source="Europe PMC"} xref: PMID:11785425 {source="Europe PMC"} xref: PMID:1444258 {source="Europe PMC"} xref: PMID:15738217 {source="Europe PMC"} xref: PMID:16075348 {source="Europe PMC"} xref: PMID:17440912 {source="Europe PMC"} xref: PMID:18097339 {source="Europe PMC"} xref: PMID:19453747 {source="Europe PMC"} xref: PMID:20172021 {source="Europe PMC"} xref: PMID:20631870 {source="Europe PMC"} xref: PMID:20718297 {source="Europe PMC"} xref: PMID:2688547 {source="Europe PMC"} xref: PMID:6354590 {source="Europe PMC"} xref: Wikipedia:Exopolysaccharide xref: Wikipedia:Extracellular_polymeric_substance is_a: CHEBI:33694 ! biomacromolecule [Term] id: CHEBI:73336 name: vulnerary namespace: chebi_ontology def: "A drug used in treating and healing of wounds." [] xref: Wikipedia:Wound_healing is_a: CHEBI:23888 ! drug [Term] id: CHEBI:73398 name: indole skeleton namespace: chebi_ontology def: "A mancude heterobicyclic organic group consisting of a benzene ring fused to a pyrrole ring." [] is_a: CHEBI:73541 ! organic heterobicyclic ring [Term] id: CHEBI:73541 name: organic heterobicyclic ring namespace: chebi_ontology def: "A bicyclic organic group that contains both carbon and hetero atoms." [] is_a: CHEBI:52845 ! cyclic organic group [Term] id: CHEBI:75763 name: eukaryotic metabolite namespace: chebi_ontology def: "Any metabolite produced during a metabolic reaction in eukaryotes, the taxon that include members of the fungi, plantae and animalia kingdoms." [] is_a: CHEBI:25212 ! metabolite [Term] id: CHEBI:75767 name: animal metabolite namespace: chebi_ontology def: "Any eukaryotic metabolite produced during a metabolic reaction in animals that include diverse creatures from sponges, insects to mammals." [] is_a: CHEBI:75763 ! eukaryotic metabolite [Term] id: CHEBI:75768 name: mammalian metabolite namespace: chebi_ontology def: "Any animal metabolite produced during a metabolic reaction in mammals." [] is_a: CHEBI:75767 ! animal metabolite [Term] id: CHEBI:75771 name: mouse metabolite namespace: chebi_ontology def: "Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus)." [] is_a: CHEBI:75768 ! mammalian metabolite [Term] id: CHEBI:75772 name: Saccharomyces cerevisiae metabolite namespace: chebi_ontology def: "Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae)." [] is_a: CHEBI:76946 ! fungal metabolite [Term] id: CHEBI:75787 name: prokaryotic metabolite namespace: chebi_ontology def: "Any metabolite produced during a metabolic reaction in prokaryotes, the taxon that include members of domains such as the bacteria and archaea." [] is_a: CHEBI:25212 ! metabolite [Term] id: CHEBI:76206 name: xenobiotic metabolite namespace: chebi_ontology def: "Any metabolite produced by metabolism of a xenobiotic compound." [] is_a: CHEBI:25212 ! metabolite [Term] id: CHEBI:76759 name: EC 3.* (hydrolase) inhibitor namespace: chebi_ontology def: "Any enzyme inhibitor that interferes with the action of a hydrolase (EC 3.*.*.*)." [] xref: Wikipedia:Hydrolase is_a: CHEBI:23924 ! enzyme inhibitor [Term] id: CHEBI:76764 name: EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor namespace: chebi_ontology def: "Any hydrolase inhibitor that interferes with the action of a hydrolase acting on C-N bonds, other than peptide bonds (EC 3.5.*.*)." [] is_a: CHEBI:76759 ! EC 3.* (hydrolase) inhibitor [Term] id: CHEBI:76807 name: EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor namespace: chebi_ontology def: "An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide linear amide C-N hydrolase (EC 3.5.1.*)." [] is_a: CHEBI:76764 ! EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor [Term] id: CHEBI:76924 name: plant metabolite namespace: chebi_ontology def: "Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms." [] is_a: CHEBI:75763 ! eukaryotic metabolite [Term] id: CHEBI:76946 name: fungal metabolite namespace: chebi_ontology def: "Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds." [] is_a: CHEBI:75763 ! eukaryotic metabolite [Term] id: CHEBI:76967 name: human xenobiotic metabolite namespace: chebi_ontology def: "Any human metabolite produced by metabolism of a xenobiotic compound in humans." [] is_a: CHEBI:76206 ! xenobiotic metabolite is_a: CHEBI:77746 ! human metabolite [Term] id: CHEBI:76969 name: bacterial metabolite namespace: chebi_ontology def: "Any prokaryotic metabolite produced during a metabolic reaction in bacteria." [] is_a: CHEBI:75787 ! prokaryotic metabolite [Term] id: CHEBI:76971 name: Escherichia coli metabolite namespace: chebi_ontology def: "Any bacterial metabolite produced during a metabolic reaction in Escherichia coli." [] is_a: CHEBI:76969 ! bacterial metabolite [Term] id: CHEBI:77746 name: human metabolite namespace: chebi_ontology def: "Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens)." [] is_a: CHEBI:75768 ! mammalian metabolite [Term] id: CHEBI:77941 name: EC 3.5.1.4 (amidase) inhibitor namespace: chebi_ontology def: "An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of amidase (EC 3.5.1.4)." [] xref: Wikipedia:Amidase is_a: CHEBI:76807 ! EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor [Term] id: CHEBI:77974 name: food packaging gas namespace: chebi_ontology def: "A food additive that is a (generally inert) gas which is used to envelop foodstuffs during packing and so protect them from unwanted chemical reactions such as food spoilage or oxidation during subsequent transport and storage. The term includes propellant gases, used to expel foods from a container." [] xref: Wikipedia:Packaging_gas is_a: CHEBI:64047 ! food additive [Term] id: CHEBI:78295 name: food component namespace: chebi_ontology def: "A physiological role played by any substance that is distributed in foodstuffs. It includes materials derived from plants or animals, such as vitamins or minerals, as well as environmental contaminants." [] is_a: CHEBI:52211 ! physiological role [Term] id: CHEBI:78433 name: refrigerant namespace: chebi_ontology def: "A substance used in a thermodynamic heat pump cycle or refrigeration cycle that undergoes a phase change from a gas to a liquid and back. Refrigerants are used in air-conditioning systems and freezers or refrigerators and are assigned a \"R\" number (by ASHRAE - formerly the American Society of Heating, Refrigerating and Air Conditioning Engineers), which is determined systematically according to their molecular structure." [] xref: Wikipedia:Refrigerant is_a: CHEBI:33232 ! application [Term] id: CHEBI:78608 name: alpha-amino acid zwitterion namespace: chebi_ontology def: "An amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of any alpha-amino acid; major species at pH 7.3." [] xref: MetaCyc:Alpha-Amino-Acids {source="SUBMITTER"} is_a: CHEBI:35238 ! amino acid zwitterion relationship: is_tautomer_of CHEBI:33704 ! alpha-amino acid [Term] id: CHEBI:78616 name: carbohydrates and carbohydrate derivatives namespace: chebi_ontology def: "Any organooxygen compound that is a polyhydroxy-aldehyde or -ketone, or a compound derived from one. Carbohydrates contain only carbon, hydrogen and oxygen and usually have an empirical formula Cm(H2O)n; carbohydrate derivatives may contain other elements by substitution or condensation." [] is_a: CHEBI:36963 ! organooxygen compound [Term] id: CHEBI:78675 name: fundamental metabolite namespace: chebi_ontology def: "Any metabolite produced by all living cells." [] is_a: CHEBI:25212 ! metabolite [Term] id: CHEBI:79387 name: trivalent inorganic anion namespace: chebi_ontology def: "Any inorganic anion with a valency of three." [] is_a: CHEBI:24834 ! inorganic anion [Term] id: CHEBI:79388 name: divalent inorganic anion namespace: chebi_ontology def: "Any inorganic anion with a valency of two." [] is_a: CHEBI:24834 ! inorganic anion [Term] id: CHEBI:79389 name: monovalent inorganic anion namespace: chebi_ontology def: "Any inorganic anion with a valency of one." [] is_a: CHEBI:24834 ! inorganic anion [Term] id: CHEBI:83039 name: crustacean metabolite namespace: chebi_ontology def: "An animal metabolite produced by arthropods such as crabs, lobsters, crayfish, shrimps and krill." [] is_a: CHEBI:75767 ! animal metabolite [Term] id: CHEBI:83056 name: Daphnia magna metabolite namespace: chebi_ontology def: "A Daphnia metabolite produced by the species Daphnia magna." [] is_a: CHEBI:83057 ! Daphnia metabolite [Term] id: CHEBI:83057 name: Daphnia metabolite namespace: chebi_ontology def: "A crustacean metabolite produced by the genus of small planktonic arthropods, Daphnia" [] xref: Wikipedia:Daphnia is_a: CHEBI:83039 ! crustacean metabolite [Term] id: CHEBI:84729 name: hydroxyindoles namespace: chebi_ontology def: "Any member of the class of indoles carrying at least one hydroxy group." [] is_a: CHEBI:24828 ! indoles is_a: CHEBI:33822 ! organic hydroxy compound [Term] id: CHEBI:84735 name: algal metabolite namespace: chebi_ontology def: "Any eukaryotic metabolite produced during a metabolic reaction in algae including unicellular organisms like chlorella and diatoms to multicellular organisms like giant kelps and brown algae." [] is_a: CHEBI:75763 ! eukaryotic metabolite [Term] id: CL:0000000 name: cell namespace: protein def: "A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane." [CARO:mah] xref: CALOHA:TS-2035 xref: FBbt:00007002 xref: FMA:68646 xref: GO:0005623 xref: KUPO:0000002 xref: MESH:D002477 xref: VHOG:0001533 xref: WBbt:0004017 xref: XAO:0003012 is_a: UBERON:0000061 ! anatomical structure disjoint_from: GO:0031012 ! extracellular matrix disjoint_from: GO:0032991 ! protein-containing complex disjoint_from: GO:0043226 ! organelle relationship: BFO:0000051 GO:0005634 {gci_filler="PATO:0001407", gci_relation="RO:0000053"} ! has part nucleus relationship: BFO:0000051 GO:0005634 {gci_filler="PATO:0001908", gci_relation="RO:0000053"} ! has part nucleus relationship: RO:0002160 NCBITaxon:131567 ! only in taxon cellular organisms property_value: skos:prefLabel "cell" xsd:string [Term] id: CL:0000005 name: fibroblast neural crest derived def: "Any fibroblast that is deriived from the neural crest." [https://orcid.org/0000-0001-5208-3432] is_a: CL:0000057 ! fibroblast is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: CL:0000057 ! fibroblast intersection_of: RO:0002202 CL:0000333 ! develops from migratory neural crest cell relationship: RO:0002202 CL:0000008 ! develops from migratory cranial neural crest cell [Term] id: CL:0000006 name: neuronal receptor cell synonym: "neuronal receptor cell (sensu Animalia)" EXACT [] is_a: CL:0000101 ! sensory neuron is_a: CL:0000197 ! sensory receptor cell intersection_of: CL:0000197 ! sensory receptor cell intersection_of: CL:0000540 ! neuron intersection_of: RO:0002215 GO:0050906 ! capable of detection of stimulus involved in sensory perception [Term] id: CL:0000007 name: early embryonic cell (metazoa) def: "A cell found in the embryo before the formation of all the gem layers is complete." [GOC:tfm] is_a: CL:0002321 ! embryonic cell (metazoa) [Term] id: CL:0000008 name: migratory cranial neural crest cell def: "Cell that is part of the migratory cranial neural crest population. Migratory cranial neural crest cells develop from premigratory cranial neural crest cells and have undergone epithelial to mesenchymal transition and delamination." [https://orcid.org/0000-0001-5208-3432, ZFA:0007091] is_a: CL:0000333 ! migratory neural crest cell [Term] id: CL:0000011 name: migratory trunk neural crest cell def: "Cell that is part of the migratory trunk neural crest population. Migratory trunk neural crest cells develop from premigratory trunk neural crest cells and have undergone epithelial to mesenchymal transition and delamination." [https://orcid.org/0000-0001-5208-3432, ZFA:0007095] is_a: CL:0000333 ! migratory neural crest cell [Term] id: CL:0000014 name: germ line stem cell def: "A stem cell that is the precursor of gametes." [doi:10.1016/j.stem.2012.05.016] synonym: "germline stem cell" EXACT [] xref: FBbt:00004861 is_a: CL:0000034 ! stem cell is_a: CL:0000039 ! germ line cell intersection_of: CL:0000039 ! germ line cell intersection_of: RO:0002215 GO:0017145 ! capable of stem cell division [Term] id: CL:0000015 name: male germ cell def: "A germ cell that supports male gamete production. In some species, non-germ cells known as Sertoli cells also play a role in spermatogenesis." [https://orcid.org/0000-0001-5208-3432, PMID:29462262] xref: FMA:72290 xref: MA:0002765 xref: ncithesaurus:Spermatogenic_Cell xref: VHOG:0001531 is_a: CL:0000586 ! germ cell relationship: RO:0002216 GO:0007283 ! capable of part of spermatogenesis [Term] id: CL:0000017 name: spermatocyte def: "A male germ cell that develops from spermatogonia. The euploid primary spermatocytes undergo meiosis and give rise to the haploid secondary spermatocytes which in turn give rise to spermatids." [GOC:tfm, MESH:D013090] xref: BTO:0001275 xref: CALOHA:TS-0951 xref: EMAPA:31484 xref: FBbt:00004936 xref: FMA:84049 xref: WBbt:0006799 is_a: CL:0000015 ! male germ cell intersection_of: CL:0000015 ! male germ cell intersection_of: RO:0002215 GO:0048137 ! capable of spermatocyte division relationship: RO:0002202 CL:0000020 ! develops from spermatogonium relationship: RO:0002215 GO:0048137 ! capable of spermatocyte division [Term] id: CL:0000018 name: spermatid def: "A male germ cell that develops from the haploid secondary spermatocytes. Without further division, spermatids undergo structural changes and give rise to spermatozoa." [MESH:D013087] synonym: "nematoblast" EXACT [] xref: BTO:0001274 xref: CALOHA:TS-0950 xref: EMAPA:31486 xref: FBbt:00004942 xref: FMA:72294 xref: WBbt:0006800 is_a: CL:0000015 ! male germ cell is_a: CL:0000255 ! eukaryotic cell is_a: CL:0000413 ! haploid cell intersection_of: CL:0000015 ! male germ cell intersection_of: RO:0000053 PATO:0001375 ! has characteristic haploid intersection_of: RO:0002215 GO:0001675 ! capable of acrosome assembly intersection_of: RO:0002215 GO:0007288 ! capable of sperm axoneme assembly intersection_of: RO:0002215 GO:0007289 ! capable of spermatid nucleus differentiation relationship: RO:0002202 CL:0000657 ! develops from secondary spermatocyte relationship: RO:0002215 GO:0001675 ! capable of acrosome assembly relationship: RO:0002215 GO:0007288 ! capable of sperm axoneme assembly relationship: RO:0002215 GO:0007289 ! capable of spermatid nucleus differentiation [Term] id: CL:0000019 name: sperm def: "A mature male germ cell that develops from a spermatid." [GOC:tfm, MESH:D013094] synonym: "sperm cell" EXACT [] synonym: "spermatozoid" EXACT [] synonym: "spermatozoon" EXACT [] xref: BTO:0001277 xref: BTO:0002046 xref: CALOHA:TS-0949 xref: FBbt:00004954 xref: FMA:67338 xref: WBbt:0006798 is_a: CL:0000255 ! eukaryotic cell is_a: CL:0000408 ! male gamete relationship: RO:0002202 CL:0000018 ! develops from spermatid [Term] id: CL:0000020 name: spermatogonium def: "An euploid male germ cell of an early stage of spermatogenesis." [MESH:D013093] synonym: "spermatogonial cell" EXACT [] xref: BTO:0000958 xref: CALOHA:TS-2193 xref: EMAPA:31482 xref: FBbt:00004934 xref: FBbt:00004935 xref: FMA:72291 is_a: CL:0000015 ! male germ cell intersection_of: CL:0000015 ! male germ cell intersection_of: RO:0000053 PATO:0001394 ! has characteristic diploid intersection_of: RO:0000053 PATO:0001501 ! has characteristic immature relationship: RO:0000053 PATO:0001394 ! has characteristic diploid relationship: RO:0000053 PATO:0001501 ! has characteristic immature [Term] id: CL:0000021 name: female germ cell def: "Female germ cell is a germ cell that supports female gamete production." [GOC:tfm, PMID:11023867, PMID:20454446] xref: MA:0000388 xref: ncithesaurus:Egg xref: VHOG:0001530 is_a: CL:0000255 ! eukaryotic cell is_a: CL:0000586 ! germ cell intersection_of: CL:0000586 ! germ cell intersection_of: RO:0002215 GO:0048477 ! capable of oogenesis relationship: RO:0002215 GO:0048477 ! capable of oogenesis [Term] id: CL:0000022 name: female germ line stem cell def: "A stem cell that is the precursor of female gametes." [doi:10.1016/j.stem.2012.05.016] xref: FBbt:00004873 is_a: CL:0000014 ! germ line stem cell is_a: CL:0000021 ! female germ cell intersection_of: CL:0000021 ! female germ cell intersection_of: RO:0002215 GO:0017145 ! capable of stem cell division [Term] id: CL:0000023 name: oocyte def: "A female germ cell that has entered meiosis." [GOC:tfm, ISBN:0721662544] xref: BTO:0000964 xref: CALOHA:TS-0711 xref: FBbt:00004886 xref: FMA:18644 xref: MESH:D009865 xref: WBbt:0006797 is_a: CL:0000021 ! female germ cell relationship: RO:0000056 GO:0007143 ! participates in female meiotic nuclear division relationship: RO:0002160 NCBITaxon:33208 ! only in taxon Metazoa [Term] id: CL:0000024 name: oogonial cell def: "An undifferentiated germ cell that proliferates rapidly and gives rise to oocytes." [GOC:tfm, ISBN:0721662544] xref: FMA:83673 is_a: CL:0000021 ! female germ cell intersection_of: CL:0000021 ! female germ cell intersection_of: RO:0002215 GO:0000278 ! capable of mitotic cell cycle relationship: RO:0002202 CL:0000670 ! develops from primordial germ cell relationship: RO:0002215 GO:0000278 ! capable of mitotic cell cycle [Term] id: CL:0000025 name: egg cell def: "A female gamete where meiosis has progressed to metaphase II and is able to participate in fertilization." [GOC:tfm, ISBN:0721662544] synonym: "mature oocyte" EXACT [] synonym: "ovum" EXACT [] xref: BTO:0000369 xref: BTO:0003801 xref: CALOHA:TS-2191 xref: FBbt:00057012 xref: FMA:67343 xref: MESH:D010063 is_a: CL:0000675 ! female gamete relationship: RO:0000056 GO:0007143 ! participates in female meiotic nuclear division relationship: RO:0002202 CL:0000023 ! develops from oocyte property_value: x_0.1:depiction "https://www.swissbiopics.org/api/image/Egg_cell.svg" xsd:anyURI [Term] id: CL:0000027 name: smooth muscle cell neural crest derived def: "A smooth muscle cell derived from the neural crest." [https://orcid.org/0000-0001-5208-3432] is_a: CL:0000192 ! smooth muscle cell is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: CL:0000192 ! smooth muscle cell intersection_of: RO:0002202 CL:0000333 ! develops from migratory neural crest cell relationship: RO:0002202 CL:0000008 ! develops from migratory cranial neural crest cell [Term] id: CL:0000029 name: neural crest derived neuron synonym: "neuron neural crest derived" EXACT [] is_a: CL:0000540 ! neuron is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: CL:0000540 ! neuron intersection_of: RO:0002202 CL:0000333 ! develops from migratory neural crest cell relationship: RO:0002202 CL:0002676 ! develops from neural crest derived neuroblast [Term] id: CL:0000031 name: neuroblast (sensu Vertebrata) def: "A cell that will develop into a neuron often after a migration phase." [GOC:NV, http://en.wikipedia.org/wiki/Neuroblast] synonym: "neuroblast" EXACT [] xref: BTO:0000930 xref: FMA:70563 is_a: CL:0000055 ! non-terminally differentiated cell is_a: CL:0000255 ! eukaryotic cell relationship: RO:0002160 NCBITaxon:7742 ! only in taxon Vertebrata [Term] id: CL:0000034 name: stem cell def: "A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [GOC:tfm, MESH:D013234] synonym: "animal stem cell" EXACT [] xref: CALOHA:TS-2086 xref: FMA:63368 is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011115 ! precursor cell intersection_of: CL:0000000 ! cell intersection_of: RO:0002215 GO:0017145 ! capable of stem cell division relationship: RO:0002162 NCBITaxon:33208 ! in taxon Metazoa relationship: RO:0002215 GO:0017145 ! capable of stem cell division [Term] id: CL:0000035 name: single fate stem cell def: "A stem cell that self-renews as well as give rise to a single mature cell type." [GOC:tfm] synonym: "unipotent stem cell" EXACT [] synonym: "unipotential stem cell" EXACT [] xref: FMA:70569 is_a: CL:0000723 ! somatic stem cell intersection_of: CL:0000000 ! cell intersection_of: RO:0000053 PATO:0001400 ! has characteristic unipotent intersection_of: RO:0002215 GO:0017145 ! capable of stem cell division relationship: RO:0000053 PATO:0001400 ! has characteristic unipotent [Term] id: CL:0000037 name: hematopoietic stem cell def: "A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. Hematopoietic stem cells lack cell markers of effector cells (lin-negative). Lin-negative is defined by lacking one or more of the following cell surface markers: CD2, CD3 epsilon, CD4, CD5 ,CD8 alpha chain, CD11b, CD14, CD19, CD20, CD56, ly6G, ter119." [GOC:add, GOC:dsd, GOC:tfm, http://en.wikipedia.org/wiki/Hematopoietic_stem_cell, PMID:19022770] synonym: "blood forming stem cell" EXACT [] synonym: "hemopoietic stem cell" EXACT [] xref: BTO:0000725 xref: CALOHA:TS-0448 xref: FMA:86475 xref: MESH:D006412 xref: VHOG:0001485 is_a: CL:0000723 ! somatic stem cell is_a: CL:0008001 ! hematopoietic precursor cell is_a: CL:0011026 ! progenitor cell intersection_of: CL:0000988 ! hematopoietic cell intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G intersection_of: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) intersection_of: RO:0002215 GO:0002244 ! capable of hematopoietic progenitor cell differentiation intersection_of: RO:0002215 GO:0048103 ! capable of somatic stem cell division relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G relationship: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) relationship: RO:0002202 CL:0000566 ! develops from angioblastic mesenchymal cell relationship: RO:0002215 GO:0002244 ! capable of hematopoietic progenitor cell differentiation [Term] id: CL:0000038 name: erythroid progenitor cell def: "A progenitor cell committed to the erythroid lineage." [GOC:add, ISBN:0721601464] xref: BTO:0004911 is_a: CL:0000764 ! erythroid lineage cell is_a: CL:0000839 ! myeloid lineage restricted progenitor cell relationship: RO:0002202 CL:0000050 ! develops from megakaryocyte-erythroid progenitor cell [Term] id: CL:0000039 name: germ line cell def: "A cell that is within the developmental lineage of gametes and is able to pass along its genetic material to offspring." [GOC:tfm, ISBN:0721662544] is_a: CL:0000000 ! cell relationship: RO:0002215 GO:0022414 ! capable of reproductive process [Term] id: CL:0000048 name: multi fate stem cell def: "A stem cell that can give rise to multiple lineages of cells." [GOC:add] synonym: "multi-fate stem cell" EXACT [] synonym: "multifate stem cell" EXACT [] synonym: "multipotent cell" EXACT [] synonym: "multipotent stem cell" EXACT [] xref: FMA:84789 is_a: CL:0000034 ! stem cell intersection_of: CL:0000000 ! cell intersection_of: RO:0000053 PATO:0001402 ! has characteristic multipotent intersection_of: RO:0002215 GO:0017145 ! capable of stem cell division relationship: RO:0000053 PATO:0001402 ! has characteristic multipotent [Term] id: CL:0000049 name: common myeloid progenitor def: "A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages." [GOC:add, ISBN:0878932437, MESH:D023461] synonym: "common myeloid precursor" EXACT [] xref: BTO:0004730 is_a: CL:0002032 ! hematopoietic oligopotent progenitor cell disjoint_from: CL:0000050 ! megakaryocyte-erythroid progenitor cell disjoint_from: CL:0000051 ! common lymphoid progenitor [Term] id: CL:0000050 name: megakaryocyte-erythroid progenitor cell def: "A progenitor cell committed to the megakaryocyte and erythroid lineages." [GOC:add, GOC:dsd, GOC:tfm, http://en.wikipedia.org/wiki/Megakaryocyte-erythroid_progenitor_cell, MESH:D055015, PMID:16647566] synonym: "CFU-EM" EXACT [] synonym: "CFU-MegE" EXACT [] synonym: "colony forming unit erythroid megakaryocyte" EXACT [] synonym: "Meg/E progenitor" EXACT [] synonym: "megakaryocyte/erythrocyte progenitor" EXACT [] synonym: "megakaryocyte/erythroid progenitor cell" EXACT [] synonym: "MEP" EXACT [] is_a: CL:0000763 ! myeloid cell is_a: CL:0002032 ! hematopoietic oligopotent progenitor cell is_a: CL:0011026 ! progenitor cell intersection_of: CL:0002032 ! hematopoietic oligopotent progenitor cell intersection_of: RO:0002215 GO:0030218 ! capable of erythrocyte differentiation intersection_of: RO:0002215 GO:0030219 ! capable of megakaryocyte differentiation relationship: RO:0002215 GO:0030218 ! capable of erythrocyte differentiation relationship: RO:0002215 GO:0030219 ! capable of megakaryocyte differentiation [Term] id: CL:0000051 name: common lymphoid progenitor def: "A oligopotent progenitor cell committed to the lymphoid lineage." [GOC:add, GOC:dsd, GOC:tfm, PMID:10407577, PMID:16551251] synonym: "common lymphocyte precursor" EXACT [] synonym: "common lymphocyte progenitor" EXACT [] synonym: "common lymphoid precursor" EXACT [] is_a: CL:0002032 ! hematopoietic oligopotent progenitor cell is_a: CL:0011026 ! progenitor cell intersection_of: CL:0002032 ! hematopoietic oligopotent progenitor cell intersection_of: RO:0002215 GO:0030098 ! capable of lymphocyte differentiation relationship: RO:0002215 GO:0030098 ! capable of lymphocyte differentiation [Term] id: CL:0000052 name: totipotent stem cell def: "A stem cell from which all cells of the body can form." [GOC:add, GOC:tfm] synonym: "totipotential stem cell" EXACT [] xref: FMA:84790 xref: MESH:D039901 is_a: CL:0000723 ! somatic stem cell [Term] id: CL:0000055 name: non-terminally differentiated cell def: "A precursor cell with a limited number of potential fates." [SANBI:mhl] synonym: "blast cell" EXACT [] xref: BTO:0000125 xref: FMA:84782 is_a: CL:0011115 ! precursor cell [Term] id: CL:0000056 name: myoblast def: "A cell that is commited to differentiating into a muscle cell. Embryonic myoblasts develop from the mesoderm. They undergo proliferation, migrate to their various sites, and then differentiate into the appropriate form of myocytes. Myoblasts also occur as transient populations of cells in muscles undergoing repair." [GOC:tfm, MESH:D032446, PMID:21849021] xref: BTO:0000222 xref: CALOHA:TS-0650 xref: FBbt:00005083 xref: FMA:70335 xref: VHOG:0001529 is_a: CL:0000680 ! muscle precursor cell [Term] id: CL:0000057 name: fibroblast def: "A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped." [http://en.wikipedia.org/wiki/Fibroblast, ISBN:0517223651, MESH:D005347] xref: BTO:0000452 xref: CALOHA:TS-0362 xref: FMA:63877 xref: NCIT:C12482 xref: VHOG:0001482 is_a: CL:0002320 ! connective tissue cell relationship: RO:0002202 CL:0000134 ! develops from mesenchymal stem cell [Term] id: CL:0000058 name: chondroblast def: "Skeletogenic cell that is typically non-terminally differentiated, secretes an avascular, GAG rich matrix; is not buried in cartilage tissue matrix, retains the ability to divide, located adjacent to cartilage tissue (including within the perichondrium), and develops from prechondroblast (and thus prechondrogenic) cell." [GO_REF:0000034, GOC:tfm, ISBN:0618947256] synonym: "chrondoplast" EXACT [] xref: BTO:0003607 xref: FMA:66783 is_a: CL:0000055 ! non-terminally differentiated cell is_a: CL:0002320 ! connective tissue cell relationship: RO:0002202 CL:0007009 ! develops from prechondroblast relationship: RO:0003000 UBERON:0002418 ! produces cartilage tissue [Term] id: CL:0000064 name: ciliated cell def: "A cell that has a filiform extrusion of the cell surface." [GOC:tfm] xref: VHOG:0001532 xref: XAO:0000031 is_a: CL:0000255 ! eukaryotic cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000000 ! cell intersection_of: BFO:0000051 GO:0005929 ! has part cilium relationship: BFO:0000051 GO:0005929 ! has part cilium [Term] id: CL:0000066 name: epithelial cell def: "A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina." [FB:ma, GOC:tfm, MESH:D004847] synonym: "epitheliocyte" EXACT [] xref: BTO:0000414 xref: CALOHA:TS-2026 xref: CARO:0000077 xref: FBbt:00000124 xref: FMA:66768 xref: WBbt:0003672 is_a: CL:0000255 ! eukaryotic cell disjoint_from: CL:0000738 ! leukocyte relationship: BFO:0000050 UBERON:0000483 ! part of epithelium property_value: skos:prefLabel "epithelial cell" xsd:string property_value: x_0.1:depiction "https://www.swissbiopics.org/api/image/Epithelial_cells.svg" xsd:anyURI [Term] id: CL:0000067 name: ciliated epithelial cell def: "An epithelial cell that has a cilia." [GOC:tfm] xref: FMA:70605 is_a: CL:0000064 ! ciliated cell is_a: CL:0000066 ! epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: BFO:0000051 GO:0005929 ! has part cilium [Term] id: CL:0000068 name: duct epithelial cell def: "An epithelial cell that is part of a duct." [https://orcid.org/0000-0001-5208-3432] is_a: CL:0000066 ! epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: BFO:0000050 UBERON:0000058 ! part of duct relationship: BFO:0000050 UBERON:0000058 ! part of duct [Term] id: CL:0000069 name: branched duct epithelial cell is_a: CL:0000068 ! duct epithelial cell [Term] id: CL:0000071 name: blood vessel endothelial cell def: "An endothelial cell that lines the vasculature." [GOC:tfm] synonym: "cuboidal endothelial cell of vascular tree" EXACT [] is_a: CL:0000076 ! squamous epithelial cell is_a: CL:0002139 ! endothelial cell of vascular tree intersection_of: CL:0000076 ! squamous epithelial cell intersection_of: BFO:0000050 UBERON:0004638 ! part of blood vessel endothelium relationship: BFO:0000050 UBERON:0004638 ! part of blood vessel endothelium relationship: RO:0002202 CL:0002546 ! develops from embryonic blood vessel endothelial progenitor cell [Term] id: CL:0000072 name: non-branched duct epithelial cell is_a: CL:0000068 ! duct epithelial cell is_a: CL:0002078 ! meso-epithelial cell [Term] id: CL:0000075 name: columnar/cuboidal epithelial cell def: "A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube." [GO:0002065, https://orcid.org/0000-0001-5208-3432] is_a: CL:0000066 ! epithelial cell [Term] id: CL:0000076 name: squamous epithelial cell xref: CALOHA:TS-1249 is_a: CL:0000066 ! epithelial cell [Term] id: CL:0000077 name: mesothelial cell def: "A flattened epithelial cell of mesenchymal origin that lines the serous cavity." [GOC:tfm, ISBN:0721662544] synonym: "mesotheliocyte" EXACT [] xref: FMA:66773 is_a: CL:0000076 ! squamous epithelial cell is_a: CL:0000213 ! lining cell is_a: CL:0002078 ! meso-epithelial cell [Term] id: CL:0000080 name: circulating cell def: "A cell which moves among different tissues of the body, via blood, lymph, or other medium." [GOC:add] is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: BFO:0000050 UBERON:0000179 ! part of haemolymphatic fluid relationship: BFO:0000050 UBERON:0000179 ! part of haemolymphatic fluid [Term] id: CL:0000081 name: blood cell def: "A cell found predominately in the blood." [GOC:add, GOC:tfm] xref: FMA:62844 xref: MESH:D001773 is_a: CL:0000988 ! hematopoietic cell intersection_of: CL:0000988 ! hematopoietic cell intersection_of: RO:0002215 GO:0008015 ! capable of blood circulation relationship: RO:0002215 GO:0008015 ! capable of blood circulation [Term] id: CL:0000082 name: epithelial cell of lung def: "An epithelial cell of the lung." [https://orcid.org/0000-0001-5208-3432] synonym: "lung epithelial cell" EXACT [] xref: BTO:0004299 is_a: CL:0000066 ! epithelial cell is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: CL:0000066 ! epithelial cell intersection_of: BFO:0000050 UBERON:0002048 ! part of lung relationship: BFO:0000050 UBERON:0000115 ! part of lung epithelium [Term] id: CL:0000083 name: epithelial cell of pancreas def: "An epithelial cell of the pancreas." [GOC:tfm] synonym: "pancreas epithelial cell" EXACT [] synonym: "pancreatic epithelial cell" EXACT [] xref: BTO:0000028 is_a: CL:0000066 ! epithelial cell is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: CL:0000066 ! epithelial cell intersection_of: BFO:0000050 UBERON:0001264 ! part of pancreas relationship: BFO:0000050 UBERON:0001264 ! part of pancreas relationship: RO:0002202 CL:0000223 ! develops from endodermal cell [Term] id: CL:0000084 name: T cell def: "A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex." [GOC:add, GOC:tfm, ISBN:0781735149] synonym: "T lymphocyte" EXACT [] synonym: "T-cell" EXACT [] synonym: "T-lymphocyte" EXACT [] xref: BTO:0000782 xref: CALOHA:TS-1001 xref: FMA:62870 xref: MESH:D013601 xref: VHOG:0001479 is_a: CL:0000542 ! lymphocyte intersection_of: CL:0000542 ! lymphocyte intersection_of: RO:0002215 GO:0002456 ! capable of T cell mediated immunity relationship: RO:0002202 CL:0000827 ! develops from pro-T cell relationship: RO:0002215 GO:0002456 ! capable of T cell mediated immunity [Term] id: CL:0000095 name: neuron associated cell is_a: CL:0002319 ! neural cell is_a: UBERON:0004121 ! ectoderm-derived structure relationship: RO:0002202 CL:0000133 ! develops from neurectodermal cell [Term] id: CL:0000098 name: sensory epithelial cell def: "A specialized epithelial cell involved in sensory perception. Restricted to special sense organs of the olfactory, gustatory, and vestibulocochlear receptor systems; contain sensory cells surrounded by supportive, non-receptive cells." [GOC:tfm, ISBN:0517223651, ISBN:0721662544] xref: BTO:0004301 is_a: CL:0000066 ! epithelial cell is_a: CL:0000197 ! sensory receptor cell intersection_of: CL:0000066 ! epithelial cell intersection_of: RO:0002215 GO:0050906 ! capable of detection of stimulus involved in sensory perception [Term] id: CL:0000099 name: interneuron def: "Most generally any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions." [GOC:tfm, MESH:D007395] xref: BTO:0003811 xref: FBbt:00005125 xref: FMA:67313 xref: WBbt:0005113 is_a: CL:0000540 ! neuron [Term] id: CL:0000100 name: motor neuron def: "An efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes or inhibits movement." [MESH:D009046, PMID:16875686] synonym: "motoneuron" EXACT [] xref: BTO:0000312 xref: FBbt:00005123 xref: FMA:83617 xref: WBbt:0005409 is_a: CL:0000527 ! efferent neuron [Term] id: CL:0000101 name: sensory neuron def: "Any neuron having a sensory function; an afferent neuron conveying sensory impulses." [ISBN:0721662544] xref: BTO:0001037 xref: FBbt:00005124 xref: FMA:84649 xref: MESH:D011984 xref: WBbt:0005759 is_a: CL:0000526 ! afferent neuron intersection_of: CL:0000540 ! neuron intersection_of: RO:0002215 GO:0050906 ! capable of detection of stimulus involved in sensory perception relationship: RO:0002215 GO:0050906 ! capable of detection of stimulus involved in sensory perception [Term] id: CL:0000107 name: autonomic neuron def: "A neuron whose cell body is within an autonomic ganglion." [GOC:tfm] xref: FMA:80121 is_a: CL:2000032 ! peripheral nervous system neuron intersection_of: CL:0000540 ! neuron intersection_of: RO:0002100 UBERON:0002410 ! has soma location autonomic nervous system relationship: RO:0002100 UBERON:0002410 ! has soma location autonomic nervous system relationship: RO:0002202 CL:0000031 ! develops from neuroblast (sensu Vertebrata) [Term] id: CL:0000108 name: cholinergic neuron def: "A neuron that uses acetylcholine as a vesicular neurotransmitter." [GOC:tfm] xref: BTO:0004902 xref: FBbt:00007173 xref: FMA:84796 xref: MESH:D059329 xref: WBbt:0006840 is_a: CL:0000151 ! secretory cell is_a: CL:0000540 ! neuron intersection_of: CL:0000540 ! neuron intersection_of: RO:0002215 GO:0014055 ! capable of acetylcholine secretion, neurotransmission relationship: RO:0002215 GO:0014055 ! capable of acetylcholine secretion, neurotransmission [Term] id: CL:0000113 name: mononuclear phagocyte def: "A vertebrate phagocyte with a single nucleus." [GOC:add, GOC:tfm, ISBN:0781735149] xref: BTO:0001433 is_a: CL:0000518 ! phagocyte (sensu Vertebrata) is_a: CL:0000842 ! mononuclear cell intersection_of: CL:0000518 ! phagocyte (sensu Vertebrata) intersection_of: RO:0000053 PATO:0001407 ! has characteristic mononucleate [Term] id: CL:0000115 name: endothelial cell def: "An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm." [GOC:tfm, http://en.wikipedia.org/wiki/Endothelial_cell, https://sourceforge.net/tracker/?func=detail&atid=440764&aid=3364936&group_id=36855, MESH:D042783, PMID:21275341] synonym: "endotheliocyte" EXACT [] xref: BTO:0001176 xref: CALOHA:TS-0278 xref: FMA:66772 is_a: CL:0000213 ! lining cell is_a: CL:0002078 ! meso-epithelial cell [Term] id: CL:0000117 name: CNS neuron (sensu Vertebrata) is_a: CL:0000540 ! neuron is_a: UBERON:0004121 ! ectoderm-derived structure relationship: BFO:0000050 UBERON:0001017 ! part of central nervous system relationship: RO:0002202 CL:0000031 ! develops from neuroblast (sensu Vertebrata) [Term] id: CL:0000125 name: glial cell def: "A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Guide neuronal migration during development, and exchange metabolites with neurons." [MESH:D009457] synonym: "neuroglial cell" EXACT [] xref: BTO:0002606 xref: CALOHA:TS-0415 xref: FBbt:00005144 xref: FMA:54536 is_a: CL:0000095 ! neuron associated cell [Term] id: CL:0000133 name: neurectodermal cell def: "Ectoderm destined to be nervous tissue." [GOC:tfm, ISBN:068340007X] synonym: "neurectoderm cell" EXACT [] is_a: CL:0000221 ! ectodermal cell [Term] id: CL:0000134 name: mesenchymal stem cell def: "A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. In humans, this cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs." [FB:ma, GOC:dsd, http://en.wikipedia.org/wiki/Mesenchymal_stem_cell, http://www.copewithcytokines.de/cope.cgi?key=mesenchymal%20stem%20cells, PMCID:PMC2613570, PMID:10102814, PMID:16923606, PMID:17986482, PMID:19960544] xref: BTO:0002625 xref: BTO:0003298 xref: FMA:70546 is_a: CL:0000048 ! multi fate stem cell is_a: CL:0002320 ! connective tissue cell [Term] id: CL:0000136 name: adipocyte def: "A fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals. Fat is usually stored in the form of triglycerides." [MESH:D017667] synonym: "adipose cell" EXACT [] synonym: "fat cell" EXACT [] xref: BTO:0000443 xref: CALOHA:TS-0012 xref: FMA:63880 is_a: CL:0000325 ! stuff accumulating cell is_a: CL:0002320 ! connective tissue cell relationship: RO:0002202 CL:0000134 ! develops from mesenchymal stem cell [Term] id: CL:0000138 name: chondrocyte def: "Skeletogenic cell that is terminally differentiated, secretes an avascular, GAG-rich matrix, is embedded in cartilage tissue matrix, retains the ability to divide, and develops from a chondroblast cell." [GO_REF:0000034, MESH:D019902] synonym: "cartilage cell" EXACT [] xref: BTO:0000249 xref: CALOHA:TS-0138 xref: FMA:66782 is_a: CL:0000153 ! glycosaminoglycan secreting cell is_a: CL:0000667 ! collagen secreting cell relationship: RO:0001025 UBERON:0002418 ! located in cartilage tissue relationship: RO:0002202 CL:0000058 ! develops from chondroblast [Term] id: CL:0000145 name: professional antigen presenting cell def: "A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response." [GOC:add, ISBN:0781735149] is_a: CL:0000738 ! leukocyte intersection_of: CL:0000738 ! leukocyte intersection_of: RO:0002215 GO:0002504 ! capable of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II relationship: RO:0002215 GO:0002504 ! capable of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [Term] id: CL:0000147 name: pigment cell def: "A pigment cell is a cell that contains pigment granules." [GOC:tfm] synonym: "chromatocyte" EXACT [] synonym: "chromatophore" EXACT [] xref: VHOG:0001678 is_a: CL:0000325 ! stuff accumulating cell [Term] id: CL:0000149 name: visual pigment cell is_a: CL:0000147 ! pigment cell [Term] id: CL:0000150 name: glandular epithelial cell def: "A specialized epithelial cell that is capable of synthesizing and secreting certain biomolecules." [GOC:tfm] synonym: "glandular epithelial cell" EXACT [] xref: CALOHA:TS-2085 xref: FMA:86494 is_a: CL:1100001 ! secretory epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: CL:0000151 ! secretory cell intersection_of: BFO:0000050 UBERON:0002530 ! part of gland relationship: BFO:0000050 UBERON:0002530 ! part of gland relationship: BFO:0000050 UBERON:0006799 ! part of glandular epithelium property_value: skos:prefLabel "glandular secretory epithelial cell" xsd:string [Term] id: CL:0000151 name: secretory cell def: "A cell that specializes in controlled release of one or more substances." [GOC:tfm, ISBN:0721662544] xref: BTO:0003659 xref: FMA:86916 is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: RO:0002215 GO:0032940 ! capable of secretion by cell relationship: RO:0002215 GO:0032940 ! capable of secretion by cell property_value: skos:prefLabel "secretory cell" xsd:string [Term] id: CL:0000152 name: exocrine cell def: "A cell of an exocrine gland; i.e. a gland that discharges its secretion via a duct." [ISBN:0198547684] xref: FMA:16014 is_a: CL:0000151 ! secretory cell is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000151 ! secretory cell intersection_of: BFO:0000050 UBERON:0002365 ! part of exocrine gland relationship: BFO:0000050 UBERON:0002365 ! part of exocrine gland [Term] id: CL:0000153 name: glycosaminoglycan secreting cell def: "A cell that secretes glycosaminoglycans." [GOC:tfm] synonym: "GAG secreting cell" EXACT [] is_a: CL:0000327 ! extracellular matrix secreting cell is_a: CL:0000447 ! carbohydrate secreting cell [Term] id: CL:0000154 name: protein secreting cell is_a: CL:0000151 ! secretory cell intersection_of: CL:0000151 ! secretory cell intersection_of: RO:0002215 GO:0009306 ! capable of protein secretion relationship: RO:0002215 GO:0009306 ! capable of protein secretion [Term] id: CL:0000159 name: seromucus secreting cell is_a: CL:0000151 ! secretory cell [Term] id: CL:0000163 name: endocrine cell def: "A cell of an endocrine gland, ductless glands that secrete substances which are released directly into the circulation and which influence metabolism and other body functions." [MESH:D055098] synonym: "endocrinocyte" EXACT [] xref: FMA:83809 is_a: CL:0000151 ! secretory cell is_a: CL:0000164 {gci_filler="UBERON:0000945", gci_relation="BFO:0000050"} ! enteroendocrine cell is_a: CL:0000164 {gci_filler="UBERON:0000160", gci_relation="BFO:0000050"} ! enteroendocrine cell is_a: CL:0000164 {gci_filler="UBERON:0001264", gci_relation="BFO:0000050"} ! enteroendocrine cell is_a: CL:0000255 ! eukaryotic cell relationship: BFO:0000050 UBERON:0000949 ! part of endocrine system [Term] id: CL:0000164 name: enteroendocrine cell def: "An endocrine cell that is located in the epithelium of the gastrointestinal tract or in the pancreas." [GOC:tfm, SANBI:mhl] xref: BTO:0003865 xref: FMA:62930 xref: MESH:D019858 is_a: CL:0000150 ! glandular epithelial cell is_a: CL:0000163 ! endocrine cell [Term] id: CL:0000165 name: neuroendocrine cell def: "A neuron that is capable of some hormone secretion in response to neuronal signals." [MESH:D055099] xref: BTO:0002691 xref: FBbt:00005130 xref: FMA:83810 is_a: CL:0000163 ! endocrine cell is_a: CL:0000527 ! efferent neuron is_a: CL:0000710 ! neurecto-epithelial cell is_a: CL:1100001 ! secretory epithelial cell intersection_of: CL:0000540 ! neuron intersection_of: RO:0002215 GO:0046879 ! capable of hormone secretion [Term] id: CL:0000167 name: peptide hormone secreting cell is_a: CL:0000151 ! secretory cell intersection_of: CL:0000151 ! secretory cell intersection_of: RO:0002215 GO:0030072 ! capable of peptide hormone secretion relationship: RO:0002215 GO:0030072 ! capable of peptide hormone secretion [Term] id: CL:0000168 name: insulin secreting cell xref: BTO:0000783 is_a: CL:0000154 ! protein secreting cell is_a: CL:0000167 ! peptide hormone secreting cell is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000151 ! secretory cell intersection_of: RO:0002215 GO:0030073 ! capable of insulin secretion relationship: RO:0002215 GO:0030073 ! capable of insulin secretion [Term] id: CL:0000169 name: type B pancreatic cell def: "A cell that secretes insulin and is located towards the center of the islets of Langerhans." [GOC:tfm, http://en.wikipedia.org/wiki/Pancreatic_b_cell, ISBN:0517223651] synonym: "B-cell of pancreatic islet" EXACT [FMA:70586] synonym: "beta cell of pancreatic islet" EXACT [FMA:70586] synonym: "insulin-secreting cell" EXACT [FMA:70586] synonym: "pancreatic B cell" EXACT [] synonym: "pancreatic B-cell" EXACT [FMA:70586] synonym: "pancreatic beta cell" EXACT [FMA:70586] synonym: "pancreatic islet core" EXACT [MA:0002419] synonym: "type B enteroendocrine cell" EXACT [FMA:70586] xref: BTO:0000783 xref: EV:0200009 xref: FMA:70586 xref: MA:0002419 xref: ncithesaurus:Beta_Cell is_a: CL:0000168 ! insulin secreting cell is_a: CL:0008024 ! pancreatic endocrine cell intersection_of: CL:0000164 ! enteroendocrine cell intersection_of: BFO:0000050 UBERON:0000006 ! part of islet of Langerhans intersection_of: RO:0002215 GO:0030073 ! capable of insulin secretion relationship: BFO:0000050 UBERON:0000006 ! part of islet of Langerhans relationship: RO:0002202 CL:0002351 ! develops from progenitor cell of endocrine pancreas [Term] id: CL:0000170 name: glucagon secreting cell def: "A cell that secretes glucagon." [GOC:tfm] synonym: "glucagon-secreting cell" EXACT [] xref: FMA:84045 is_a: CL:0000167 ! peptide hormone secreting cell intersection_of: CL:0000151 ! secretory cell intersection_of: RO:0002215 GO:0070091 ! capable of glucagon secretion relationship: RO:0002215 GO:0070091 ! capable of glucagon secretion [Term] id: CL:0000171 name: pancreatic A cell def: "A type of enteocrine cell found in the periphery of the islets of Langerhans that secretes glucagon." [GOC:tfm, ISBN:0721662544] synonym: "alpha cell of islet of Langerhans" EXACT [] synonym: "pancreatic alpha cell" EXACT [] xref: BTO:0000990 xref: FMA:70585 xref: MESH:D050416 is_a: CL:0002067 ! type A enteroendocrine cell is_a: CL:0008024 ! pancreatic endocrine cell intersection_of: CL:0002067 ! type A enteroendocrine cell intersection_of: BFO:0000050 UBERON:0001264 ! part of pancreas relationship: BFO:0000050 UBERON:0000006 ! part of islet of Langerhans relationship: RO:0002202 CL:0002351 ! develops from progenitor cell of endocrine pancreas [Term] id: CL:0000172 name: somatostatin secreting cell is_a: CL:0000167 ! peptide hormone secreting cell intersection_of: CL:0000151 ! secretory cell intersection_of: RO:0002215 GO:0070253 ! capable of somatostatin secretion relationship: RO:0002215 GO:0070253 ! capable of somatostatin secretion [Term] id: CL:0000173 name: pancreatic D cell def: "A D cell located in the pancreas. Peripherally placed within the islets like type A cells; contains somatostatin." [FMA:0517223651, GOC:tfm] synonym: "D-cell of pancreatic islet" EXACT [] synonym: "delta cell of islet" EXACT [] synonym: "delta cell of pancreatic islet" EXACT [] synonym: "pancreatic D-cell" EXACT [] synonym: "pancreatic delta cell" EXACT [] synonym: "somatostatin-secreting pancreatic cell" EXACT [] xref: BTO:0000803 xref: FMA:70587 is_a: CL:0000502 ! type D enteroendocrine cell is_a: CL:0008024 ! pancreatic endocrine cell intersection_of: CL:0000502 ! type D enteroendocrine cell intersection_of: BFO:0000050 UBERON:0001264 ! part of pancreas relationship: BFO:0000050 UBERON:0000006 ! part of islet of Langerhans relationship: RO:0002202 CL:0002351 ! develops from progenitor cell of endocrine pancreas [Term] id: CL:0000174 name: steroid hormone secreting cell is_a: CL:0000151 ! secretory cell intersection_of: CL:0000151 ! secretory cell intersection_of: RO:0002215 GO:0035929 ! capable of steroid hormone secretion relationship: RO:0002215 GO:0035929 ! capable of steroid hormone secretion [Term] id: CL:0000182 name: hepatocyte def: "The main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. Majority of cell population of liver, polygonal in shape, arranged in plates or trabeculae between sinusoids; may have single nucleus or binucleated." [GOC:tfm, http://en.wikipedia.org/wiki/Hepatocyte, ISBN:0412046911, MESH:D022781, PMID:19717280] xref: BTO:0000575 xref: CALOHA:TS-0454 xref: FMA:14515 is_a: CL:0000066 ! epithelial cell is_a: CL:0000417 ! endopolyploid cell is_a: UBERON:0004119 ! endoderm-derived structure relationship: BFO:0000050 UBERON:0002107 ! part of liver relationship: RO:0002202 CL:0005026 ! develops from hepatoblast relationship: RO:0002215 GO:0006699 ! capable of bile acid biosynthetic process relationship: RO:0002215 GO:0098754 ! capable of detoxification [Term] id: CL:0000183 name: contractile cell def: "A cell whose primary function is to shorten." [FB:ma] is_a: CL:0000000 ! cell [Term] id: CL:0000187 name: muscle cell def: "A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns." [MESH:D032342] synonym: "muscle fiber" EXACT [] synonym: "myocyte" EXACT [] xref: BTO:0000888 xref: BTO:0000902 xref: CALOHA:TS-2032 xref: FBbt:00005074 xref: FMA:67328 xref: WBbt:0003675 is_a: CL:0000183 ! contractile cell is_a: CL:0000255 ! eukaryotic cell is_a: CL:0000393 ! electrically responsive cell is_a: UBERON:0004120 ! mesoderm-derived structure relationship: RO:0002202 CL:0000056 ! develops from myoblast property_value: x_0.1:depiction "https://www.swissbiopics.org/api/image/Muscle_cells.svg" xsd:anyURI [Term] id: CL:0000188 name: cell of skeletal muscle def: "A somatic cell located in skeletal muscle." [GOC:tfm] synonym: "skeletal muscle cell" EXACT [] xref: BTO:0004392 xref: CALOHA:TS-2158 xref: FMA:9727 is_a: CL:0000255 ! eukaryotic cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000000 ! cell intersection_of: BFO:0000050 UBERON:0001134 ! part of skeletal muscle tissue relationship: BFO:0000050 UBERON:0001134 ! part of skeletal muscle tissue property_value: skos:prefLabel "cell of skeletal muscle" xsd:string [Term] id: CL:0000192 name: smooth muscle cell def: "A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast)." [http://en.wikipedia.org/wiki/Smooth_muscle_cell, MESH:D032389, PMID:9315361] synonym: "myocytes, smooth muscle" EXACT [MESH:D032389] synonym: "SMCs" EXACT [PMID:9315361] synonym: "smooth muscle fiber" EXACT [] xref: BTO:0004576 xref: CALOHA:TS-2159 xref: FMA:14072 is_a: CL:0008000 ! non-striated muscle cell is_a: CL:0008007 ! visceral muscle cell relationship: RO:0002202 CL:0000514 ! develops from smooth muscle myoblast [Term] id: CL:0000197 name: sensory receptor cell def: "A cell that is capable of detection of a stimulus involved in sensory perception." [] synonym: "receptor cell" EXACT [] xref: MESH:D011984 is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: BFO:0000050 UBERON:0001032 ! part of sensory system intersection_of: RO:0002215 GO:0050906 ! capable of detection of stimulus involved in sensory perception relationship: BFO:0000050 UBERON:0001032 ! part of sensory system relationship: RO:0002215 GO:0050906 ! capable of detection of stimulus involved in sensory perception [Term] id: CL:0000206 name: chemoreceptor cell def: "A cell specialized to detect chemical substances and relay that information centrally in the nervous system. Chemoreceptors may monitor external stimuli, as in taste and olfaction, or internal stimuli, such as the concentrations of oxygen and carbon dioxide in the blood." [MESH:D002628] is_a: CL:0000197 ! sensory receptor cell intersection_of: CL:0000197 ! sensory receptor cell intersection_of: RO:0002215 GO:0050907 ! capable of detection of chemical stimulus involved in sensory perception relationship: RO:0002215 GO:0050907 ! capable of detection of chemical stimulus involved in sensory perception [Term] id: CL:0000210 name: photoreceptor cell def: "A cell specialized to detect and transduce light." [MESH:D010786] xref: BTO:0001060 xref: CALOHA:TS-0868 xref: FMA:86740 is_a: CL:0000006 ! neuronal receptor cell intersection_of: CL:0000540 ! neuron intersection_of: RO:0002215 GO:0050962 ! capable of detection of light stimulus involved in sensory perception relationship: RO:0002215 GO:0050962 ! capable of detection of light stimulus involved in sensory perception property_value: x_0.1:depiction "https://www.swissbiopics.org/api/image/Photoreceptor_cell.svg" xsd:anyURI [Term] id: CL:0000211 name: electrically active cell def: "A cell whose function is determined by the generation or the reception of an electric signal." [FB:ma] is_a: CL:0000000 ! cell [Term] id: CL:0000213 name: lining cell def: "A cell within an epithelial cell sheet whose main function is to act as an internal or external covering for a tissue or an organism." [JB:jb] synonym: "boundary cell" EXACT [] is_a: CL:0000215 ! barrier cell [Term] id: CL:0000214 name: synovial cell def: "A cell located in the synovial joint." [] synonym: "synoviocyte" EXACT [] xref: CALOHA:TS-0995 is_a: CL:0000213 ! lining cell is_a: CL:0002078 ! meso-epithelial cell relationship: BFO:0000050 UBERON:0002217 ! part of synovial joint [Term] id: CL:0000215 name: barrier cell def: "A cell whose primary function is to prevent the transport of stuff across compartments." [JB:jb] is_a: CL:0000000 ! cell [Term] id: CL:0000216 name: Sertoli cell def: "A supporting cell projecting inward from the basement membrane of seminiferous tubules. They surround and nourish the developing male germ cells and secrete androgen binding protein. Their tight junctions with the spermatogonia and spermatocytes provide a blood-testis barrier." [MESH:D012708] xref: BTO:0001238 xref: CALOHA:TS-0922 xref: FMA:72298 xref: VHOG:0001348 is_a: CL:0000511 ! androgen binding protein secreting cell is_a: CL:0000630 ! supporting cell is_a: CL:0002625 ! seminiferous tubule epithelial cell is_a: CL:1100001 ! secretory epithelial cell intersection_of: CL:0000630 ! supporting cell intersection_of: BFO:0000050 UBERON:0001343 ! part of seminiferous tubule of testis [Term] id: CL:0000219 name: motile cell def: "A cell that moves by its own activities." [FB:ma] is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: RO:0002215 GO:0048870 ! capable of cell motility relationship: RO:0002215 GO:0048870 ! capable of cell motility [Term] id: CL:0000221 name: ectodermal cell def: "A cell of the outer of the three germ layers of the embryo." [MESH:D004475] synonym: "ectoderm cell" EXACT [] xref: FMA:72549 is_a: CL:0000255 ! eukaryotic cell is_a: CL:0002321 ! embryonic cell (metazoa) relationship: BFO:0000050 UBERON:0000924 ! part of ectoderm property_value: skos:prefLabel "ectodermal cell" xsd:string [Term] id: CL:0000222 name: mesodermal cell def: "A cell of the middle germ layer of the embryo." [MESH:D008648] synonym: "mesoblast" EXACT [] synonym: "mesoderm cell" EXACT [] xref: FMA:72554 is_a: CL:0000255 ! eukaryotic cell is_a: CL:0002321 ! embryonic cell (metazoa) relationship: BFO:0000050 UBERON:0000926 ! part of mesoderm [Term] id: CL:0000223 name: endodermal cell def: "A cell of the inner of the three germ layers of the embryo." [MESH:D004707] synonym: "endoderm cell" EXACT [] xref: FMA:72555 is_a: CL:0000255 ! eukaryotic cell is_a: CL:0002321 ! embryonic cell (metazoa) relationship: BFO:0000050 UBERON:0000925 ! part of endoderm [Term] id: CL:0000225 name: anucleate cell def: "A cell that lacks a nucleus." [FB:ma] synonym: "non-nucleated cell" EXACT [] xref: FMA:68647 is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: RO:0000053 PATO:0001405 ! has characteristic anucleate disjoint_from: CL:0002242 ! nucleate cell relationship: RO:0000053 PATO:0001405 ! has characteristic anucleate [Term] id: CL:0000226 name: single nucleate cell def: "A cell with a single nucleus." [FB:ma, GOC:tfm] is_a: CL:0000255 ! eukaryotic cell is_a: CL:0002242 ! nucleate cell intersection_of: CL:0000000 ! cell intersection_of: RO:0000053 PATO:0001407 ! has characteristic mononucleate relationship: RO:0000053 PATO:0001407 ! has characteristic mononucleate [Term] id: CL:0000227 name: binucleate cell is_a: CL:0000228 ! multinucleate cell intersection_of: CL:0000000 ! cell intersection_of: RO:0000053 PATO:0001406 ! has characteristic binucleate relationship: RO:0000053 PATO:0001406 ! has characteristic binucleate [Term] id: CL:0000228 name: multinucleate cell def: "A cell with more than one nucleus." [FB:ma] synonym: "syncitium" EXACT [] synonym: "syncytial cell" EXACT [] synonym: "syncytium" EXACT [] xref: AEO:0000203 xref: WBbt:0008074 is_a: CL:0000255 ! eukaryotic cell is_a: CL:0002242 ! nucleate cell intersection_of: CL:0000000 ! cell intersection_of: RO:0000053 PATO:0001908 ! has characteristic multinucleate relationship: RO:0000053 PATO:0001908 ! has characteristic multinucleate [Term] id: CL:0000232 name: erythrocyte def: "A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen." [GOC:tfm, MESH:D004912] synonym: "RBC" EXACT [] synonym: "red blood cell" EXACT [] xref: BTO:0000424 xref: CALOHA:TS-0290 xref: FMA:81100 is_a: CL:0000081 ! blood cell is_a: CL:0000329 ! oxygen accumulating cell is_a: CL:0000764 ! erythroid lineage cell intersection_of: CL:0000764 ! erythroid lineage cell intersection_of: CL:4030045 GO:0005840 ! lacks_part ribosome intersection_of: CL:4030046 PR:000001945 ! lacks_plasma_membrane_part transferrin receptor protein 1 intersection_of: RO:0000053 PATO:0002039 ! has characteristic biconcave intersection_of: RO:0002215 GO:0008015 ! capable of blood circulation intersection_of: RO:0002215 GO:0015671 ! capable of oxygen transport relationship: CL:4030045 GO:0005840 ! lacks_part ribosome relationship: CL:4030046 PR:000001945 ! lacks_plasma_membrane_part transferrin receptor protein 1 relationship: RO:0000053 PATO:0002039 ! has characteristic biconcave relationship: RO:0002202 CL:0000558 ! develops from reticulocyte [Term] id: CL:0000234 name: phagocyte def: "Any cell capable of ingesting particulate matter via phagocytosis." [GOC:add, ISBN:0721601464] xref: BTO:0001044 xref: FMA:83806 xref: MESH:D010586 is_a: CL:0000219 ! motile cell is_a: CL:0000325 ! stuff accumulating cell is_a: CL:0000473 ! defensive cell intersection_of: CL:0000000 ! cell intersection_of: RO:0002215 GO:0006909 ! capable of phagocytosis relationship: RO:0002215 GO:0006909 ! capable of phagocytosis [Term] id: CL:0000255 name: eukaryotic cell def: "Any cell that in taxon some Eukaryota." [FBC:Autogenerated] xref: MESH:D005057 is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: RO:0002160 NCBITaxon:2759 ! only in taxon Eukaryota intersection_of: RO:0002162 NCBITaxon:2759 ! in taxon Eukaryota relationship: RO:0002160 NCBITaxon:2759 ! only in taxon Eukaryota property_value: skos:prefLabel "eukaryotic cell" xsd:string [Term] id: CL:0000257 name: Eumycetozoan cell is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: RO:0002160 NCBITaxon:142796 ! only in taxon Eumycetozoa relationship: RO:0002160 NCBITaxon:142796 ! only in taxon Eumycetozoa [Term] id: CL:0000287 name: eye photoreceptor cell is_a: CL:0000210 ! photoreceptor cell intersection_of: CL:0000210 ! photoreceptor cell intersection_of: BFO:0000050 UBERON:0000970 ! part of eye relationship: BFO:0000050 UBERON:0000970 ! part of eye [Term] id: CL:0000293 name: structural cell def: "A cell whose primary function is to provide structural support, to provide strength and physical integrity to the organism." [TAIR:sr] is_a: CL:0000000 ! cell [Term] id: CL:0000300 name: gamete def: "A mature sexual reproductive cell having a single set of unpaired chromosomes." [GOC:tfm, ISBN:0721662544] synonym: "haploid nucleated cell" EXACT [] xref: CALOHA:TS-0395 xref: FBbt:00005412 xref: FMA:18649 is_a: CL:0000413 ! haploid cell is_a: CL:0000586 ! germ cell intersection_of: CL:0000586 ! germ cell intersection_of: RO:0000053 PATO:0001375 ! has characteristic haploid intersection_of: RO:0002215 GO:0009566 ! capable of fertilization relationship: RO:0002215 GO:0009566 ! capable of fertilization [Term] id: CL:0000306 name: crystallin accumulating cell synonym: "lens cell" EXACT [] is_a: CL:0000325 ! stuff accumulating cell [Term] id: CL:0000313 name: serous secreting cell def: "Columnar glandular cell with irregular nucleus, copious granular endoplasmic reticulum and supranuclear granules. Secretes a watery fluid containing proteins known as serous fluid." [GOC:tfm, ISBN:0517223651, ISBN:0721662544] synonym: "serous cell" EXACT [] xref: BTO:0003687 xref: FMA:62511 is_a: CL:0000159 ! seromucus secreting cell [Term] id: CL:0000319 name: mucus secreting cell synonym: "mucous cell" EXACT [] xref: BTO:0003689 is_a: CL:0000159 ! seromucus secreting cell intersection_of: CL:0000151 ! secretory cell intersection_of: RO:0002215 GO:0070254 ! capable of mucus secretion relationship: RO:0002215 GO:0070254 ! capable of mucus secretion [Term] id: CL:0000325 name: stuff accumulating cell def: "A cell that is specialised to accumulate a particular substance(s)." [FB:ma] is_a: CL:0000000 ! cell [Term] id: CL:0000327 name: extracellular matrix secreting cell is_a: CL:0000499 ! stromal cell [Term] id: CL:0000329 name: oxygen accumulating cell is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: RO:0002215 GO:0015671 ! capable of oxygen transport relationship: RO:0002215 GO:0015671 ! capable of oxygen transport [Term] id: CL:0000333 name: migratory neural crest cell def: "A cell derived from the specialized ectoderm flanking each side of the embryonic neural plate, which after the closure of the neural tube, forms masses of cells that migrate out from the dorsal aspect of the neural tube to spread throughout the body." [doi:10.1016/j.stem.2015.02.017] xref: FMA:86667 is_a: CL:0000219 ! motile cell is_a: CL:0011012 ! neural crest cell is_a: CL:0011026 ! progenitor cell is_a: UBERON:0010313 ! neural crest-derived structure relationship: RO:0002202 CL:0007004 ! develops from premigratory neural crest cell [Term] id: CL:0000335 name: mesenchyme condensation cell def: "A mesenchymal cell in embryonic development found in a contracting mass and that gives rise to osteoprogenitors." [GOC:tfm, PMID:5025404] is_a: CL:0008019 ! mesenchymal cell [Term] id: CL:0000347 name: scleral cell def: "A cell of the sclera of the eye." [GOC:add] is_a: CL:0000255 ! eukaryotic cell is_a: CL:0000293 ! structural cell is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: CL:0000293 ! structural cell intersection_of: BFO:0000050 UBERON:0001773 ! part of sclera relationship: BFO:0000050 UBERON:0001773 ! part of sclera relationship: RO:0002202 CL:0000008 ! develops from migratory cranial neural crest cell [Term] id: CL:0000348 name: choroidal cell of the eye def: "A structural cell that is part of optic choroid." [GOC:add] is_a: CL:0000255 ! eukaryotic cell is_a: CL:0000293 ! structural cell is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: CL:0000293 ! structural cell intersection_of: BFO:0000050 UBERON:0001776 ! part of optic choroid relationship: BFO:0000050 UBERON:0001776 ! part of optic choroid relationship: RO:0002202 CL:0000008 ! develops from migratory cranial neural crest cell [Term] id: CL:0000349 name: extraembryonic cell is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: BFO:0000050 UBERON:0000478 ! part of extraembryonic structure relationship: BFO:0000050 UBERON:0000478 ! part of extraembryonic structure [Term] id: CL:0000351 name: trophoblast cell def: "A cell lining the outside of the blastocyst. After binding to the endometrium, trophoblast cells develop into two distinct layers, an inner layer of mononuclear cytotrophoblast cells and an outer layer of continuous multinuclear cytoplasm, the syncytiotrophoblast cells, which form the early fetal-maternal interface." [GOC:tfm, MESH:D014327] synonym: "trophoblastic cell" EXACT [] xref: FMA:83028 is_a: CL:0000349 ! extraembryonic cell relationship: BFO:0000050 UBERON:0000358 ! part of blastocyst [Term] id: CL:0000352 name: epiblast cell def: "A cell of the outer layer of a blastula that gives rise to the ectoderm after gastrulation." [GOC:tfm, ISBN:0618947256] is_a: CL:0000052 ! totipotent stem cell [Term] id: CL:0000353 name: blastoderm cell def: "An undifferentiated cell produced by early cleavages of the fertilized egg (zygote)." [MESH:D001756] synonym: "blastomere" EXACT [] xref: BTO:0001473 xref: FMA:72551 is_a: CL:0000007 ! early embryonic cell (metazoa) [Term] id: CL:0000354 name: blastemal cell synonym: "blastema cell" EXACT [] xref: ncithesaurus:Blastemal_Cell is_a: CL:0000048 ! multi fate stem cell [Term] id: CL:0000355 name: multi-potent skeletal muscle stem cell def: "A multifate stem cell found in skeletal muscle than can differentiate into many different cell types, including muscle. Distinct cell type from satellite cell." [PMID:18282570] xref: FMA:86767 is_a: CL:0000048 ! multi fate stem cell is_a: CL:0000188 ! cell of skeletal muscle intersection_of: CL:0000048 ! multi fate stem cell intersection_of: BFO:0000050 UBERON:0001134 ! part of skeletal muscle tissue [Term] id: CL:0000358 name: sphincter associated smooth muscle cell def: "A smooth muscle cell that is part of a sphincter. A sphincter is a typically circular muscle that normally maintains constriction of a natural body passage or orifice and which relaxes as required by normal physiological functioning." [GOC:cjm] is_a: CL:0000192 ! smooth muscle cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: BFO:0000050 UBERON:0004590 ! part of sphincter muscle relationship: BFO:0000050 UBERON:0004590 ! part of sphincter muscle [Term] id: CL:0000359 name: vascular associated smooth muscle cell def: "A smooth muscle cell associated with the vasculature." [GOC:dsd, GOC:tfm] synonym: "vascular smooth muscle cell" EXACT [] synonym: "VSMC" EXACT [] is_a: CL:0000192 ! smooth muscle cell is_a: CL:4033054 ! perivascular cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: BFO:0000050 UBERON:0002049 ! part of vasculature relationship: BFO:0000050 UBERON:0002049 ! part of vasculature [Term] id: CL:0000362 name: epidermal cell def: "An epithelial cell of the integument (the outer layer of an organism)." [Flybase:dsj, MA:ma] synonym: "cell of epidermis" EXACT [FMA:62411] xref: BTO:0001470 xref: CALOHA:TS-0283 xref: FMA:62411 xref: MESH:D000078404 is_a: CL:0002159 ! general ecto-epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: BFO:0000050 UBERON:0007376 ! part of outer epithelium relationship: BFO:0000050 UBERON:0007376 ! part of outer epithelium [Term] id: CL:0000365 name: animal zygote def: "Diploid cell produced by the fusion of sperm cell nucleus and egg cell." [ISBN:0471245208] xref: BTO:0000854 xref: EHDAA2:0004546 xref: FMA:72395 is_a: CL:0000007 ! early embryonic cell (metazoa) is_a: CL:0000255 ! eukaryotic cell is_a: CL:0010017 ! zygote intersection_of: CL:0010017 ! zygote intersection_of: RO:0002160 NCBITaxon:33208 ! only in taxon Metazoa relationship: RO:0002160 NCBITaxon:33208 ! only in taxon Metazoa [Term] id: CL:0000393 name: electrically responsive cell def: "A cell whose function is determined by its response to an electric signal." [FB:ma] is_a: CL:0000211 ! electrically active cell [Term] id: CL:0000397 name: ganglion interneuron is_a: CL:0000099 ! interneuron intersection_of: CL:0000099 ! interneuron intersection_of: RO:0002100 UBERON:0000045 ! has soma location ganglion relationship: RO:0002100 UBERON:0000045 ! has soma location ganglion [Term] id: CL:0000402 name: CNS interneuron def: "An interneuron that has its cell body in a central nervous system." [doi:10.1016/B978-0-12-817424-1.00001-X] is_a: CL:0000099 ! interneuron is_a: CL:2000029 ! central nervous system neuron intersection_of: CL:0000099 ! interneuron intersection_of: RO:0002100 UBERON:0001017 ! has soma location central nervous system [Term] id: CL:0000404 name: electrically signaling cell def: "A cell that initiates an electrical signal and passes that signal to another cell." [FB:ma] is_a: CL:0000211 ! electrically active cell [Term] id: CL:0000408 name: male gamete xref: BTO:0001277 xref: CALOHA:TS-0949 is_a: CL:0000015 ! male germ cell is_a: CL:0000300 ! gamete intersection_of: CL:0000015 ! male germ cell intersection_of: RO:0000053 PATO:0001375 ! has characteristic haploid intersection_of: RO:0002215 GO:0009566 ! capable of fertilization [Term] id: CL:0000412 name: polyploid cell def: "A cell that contains more than two haploid sets of chromosomes." [FB:ma, https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Biology_(Kimball)/07%3A_Cell_Division/7.04%3A_Polyploidy, PMID:32646579] is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: RO:0000053 PATO:0001377 ! has characteristic polyploid relationship: RO:0000053 PATO:0001377 ! has characteristic polyploid [Term] id: CL:0000413 name: haploid cell def: "A cell whose nucleus contains a single haploid genome." [FB:ma, GOC:tfm] is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: RO:0000053 PATO:0001375 ! has characteristic haploid relationship: RO:0000053 PATO:0001375 ! has characteristic haploid [Term] id: CL:0000417 name: endopolyploid cell is_a: CL:0000412 ! polyploid cell [Term] id: CL:0000447 name: carbohydrate secreting cell is_a: CL:0000151 ! secretory cell [Term] id: CL:0000451 name: dendritic cell def: "A cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. These cells are lineage negative (CD3-negative, CD19-negative, CD34-negative, and CD56-negative)." [GOC:add, ISBN:0781735149] xref: BTO:0002042 xref: CALOHA:TS-0194 xref: FMA:83036 xref: MESH:D003713 is_a: CL:0000113 ! mononuclear phagocyte is_a: CL:0000145 ! professional antigen presenting cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000738 ! leukocyte intersection_of: BFO:0000051 GO:0042613 ! has part MHC class II protein complex intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule intersection_of: CL:4030046 PR:000001003 ! lacks_plasma_membrane_part CD34 molecule intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 intersection_of: RO:0000053 PATO:0001407 ! has characteristic mononucleate intersection_of: RO:0002215 GO:0001816 ! capable of cytokine production intersection_of: RO:0002215 GO:0002504 ! capable of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II intersection_of: RO:0002215 GO:0019882 ! capable of antigen processing and presentation intersection_of: RO:0002215 GO:0045580 ! capable of regulation of T cell differentiation disjoint_from: CL:0000542 ! lymphocyte relationship: BFO:0000051 GO:0042613 ! has part MHC class II protein complex relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule relationship: CL:4030046 PR:000001003 ! lacks_plasma_membrane_part CD34 molecule relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 relationship: RO:0002215 GO:0001816 ! capable of cytokine production relationship: RO:0002215 GO:0045580 ! capable of regulation of T cell differentiation [Term] id: CL:0000457 name: biogenic amine secreting cell is_a: CL:0000151 ! secretory cell [Term] id: CL:0000458 name: serotonin secreting cell def: "A cell type that secretes 5-Hydroxytryptamine (serotonin)." [GOC:tfm, PMID:19630576] synonym: "5-HT secreting cell" EXACT [] synonym: "5-Hydroxytryptamine secreting cell" EXACT [] is_a: CL:0000457 ! biogenic amine secreting cell intersection_of: CL:0000151 ! secretory cell intersection_of: RO:0002215 GO:0001820 ! capable of serotonin secretion relationship: RO:0002215 GO:0001820 ! capable of serotonin secretion [Term] id: CL:0000459 name: noradrenergic cell def: "A cell capable of producting norepiniphrine. Norepiniphrine is a catecholamine with multiple roles including as a hormone and a neurotransmitter. In addition, epiniphrine is synthesized from norepiniphrine by the actions of the phenylethanolamine N-methyltransferase enzyme." [GOC:tfm, ISBN:068340007X] synonym: "noradrenaline secreting cell" EXACT [] synonym: "norepinephrin secreting cell" EXACT [] synonym: "norepinephrine secreting cell" EXACT [] is_a: CL:0000457 ! biogenic amine secreting cell intersection_of: CL:0000151 ! secretory cell intersection_of: RO:0002215 GO:0048243 ! capable of norepinephrine secretion relationship: RO:0002215 GO:0048243 ! capable of norepinephrine secretion [Term] id: CL:0000473 name: defensive cell def: "A cell whose primary function is to protect the organism." [JB:jb] is_a: CL:0000000 ! cell [Term] id: CL:0000488 name: visible light photoreceptor cell def: "A photoreceptor cell that detects visible light." [GOC:tfm] is_a: CL:0000210 ! photoreceptor cell intersection_of: CL:0000210 ! photoreceptor cell intersection_of: RO:0002215 GO:0009584 ! capable of detection of visible light relationship: RO:0002215 GO:0009584 ! capable of detection of visible light [Term] id: CL:0000499 name: stromal cell def: "A connective tissue cell of an organ found in the loose connective tissue. These are most often associated with the uterine mucosa and the ovary as well as the hematopoietic system and elsewhere." [GOC:tfm, MESH:D017154] xref: BTO:0002064 xref: FMA:83624 is_a: CL:0002320 ! connective tissue cell relationship: RO:0002202 CL:0000134 ! develops from mesenchymal stem cell [Term] id: CL:0000502 name: type D enteroendocrine cell def: "A cell found throughout the gastrointestinal tract and in the pancreas. They secrete somatostatin in both an endocrine and paracrine manner. Somatostatin inhibits gastrin, cholecystokinin, insulin, glucagon, pancreatic enzymes, and gastric hydrochloric acid. A variety of substances which inhibit gastric acid secretion (vasoactive intestinal peptide, calcitonin gene-related peptide, cholecystokinin, beta-adrenergic agonists, and gastric inhibitory peptide) are thought to act by releasing somatostatin." [MESH:D019864] synonym: "D cell" EXACT [] xref: FMA:62935 is_a: CL:0000164 ! enteroendocrine cell is_a: CL:0000172 ! somatostatin secreting cell [Term] id: CL:0000506 name: enkephalin secreting cell def: "An endorphine cell that secretes enkephalin." [GO:tfm] is_a: CL:0000507 ! endorphin secreting cell [Term] id: CL:0000507 name: endorphin secreting cell def: "A peptide hormone secreting cell that secretes endorphin." [GO:tfm] is_a: CL:0000167 ! peptide hormone secreting cell [Term] id: CL:0000508 name: type G enteroendocrine cell def: "An endocrine cell found in the pyloric gland mucosa (antral mucosa) of the stomach of mammals and responsible for the secretion of gastrin and enkephalin. Most abundant in pyloric antrum, pyramidal in form with a narrow apex bearing long microvilli." [GOC:tfm, ISBN:0517223651, MESH:D019863] synonym: "G cell" EXACT [] xref: BTO:0004108 xref: FMA:67609 is_a: CL:0000164 ! enteroendocrine cell is_a: CL:0000506 ! enkephalin secreting cell is_a: CL:0000509 ! gastrin secreting cell is_a: CL:0002180 ! mucous cell of stomach relationship: BFO:0000050 UBERON:0004997 ! part of mucosa of pyloric antrum [Term] id: CL:0000509 name: gastrin secreting cell def: "A peptide hormone secreting cell that secretes gastrin." [GO:tfm] is_a: CL:0000167 ! peptide hormone secreting cell [Term] id: CL:0000511 name: androgen binding protein secreting cell def: "A peptide hormone secreting cell that secretes androgen binding protein." [GO:tfm] is_a: CL:0000154 ! protein secreting cell [Term] id: CL:0000513 name: cardiac muscle myoblast def: "A precursor cell destined to differentiate into cardiac muscle cell." [GOC:tfm, MESH:D032386] synonym: "cardiac muscle progenitor cell" EXACT [] synonym: "cardiomyocyte progenitor cell" EXACT [] xref: FMA:84797 is_a: CL:0002494 ! cardiocyte is_a: CL:0010021 ! cardiac myoblast intersection_of: CL:0000056 ! myoblast intersection_of: BFO:0000050 UBERON:0001133 ! part of cardiac muscle tissue intersection_of: RO:0002203 CL:0000746 ! develops into cardiac muscle cell relationship: BFO:0000050 UBERON:0001133 ! part of cardiac muscle tissue [Term] id: CL:0000514 name: smooth muscle myoblast def: "A precursor cell destined to differentiate into smooth muscle myocytes." [GOC:tfm, MESH:D032390] synonym: "myoblast, smooth muscle" EXACT [MESH:D032390] xref: FMA:84798 is_a: CL:0000056 ! myoblast intersection_of: CL:0000056 ! myoblast intersection_of: RO:0002203 CL:0000192 ! develops into smooth muscle cell relationship: RO:0002203 CL:0000192 ! develops into smooth muscle cell [Term] id: CL:0000515 name: skeletal muscle myoblast def: "A myoblast that differentiates into skeletal muscle fibers." [SANBI:mhl] synonym: "skeletal myoblast" EXACT [] xref: FMA:84799 is_a: CL:0000056 ! myoblast is_a: CL:0011026 ! progenitor cell intersection_of: CL:0000056 ! myoblast intersection_of: RO:0002203 CL:0008002 ! develops into skeletal muscle fiber relationship: RO:0002202 CL:0000355 ! develops from multi-potent skeletal muscle stem cell relationship: RO:0002203 CL:0008002 ! develops into skeletal muscle fiber [Term] id: CL:0000518 name: phagocyte (sensu Vertebrata) def: "A phagocyte in vertebrates that is able to phagocytosis." [GOC:tfm] is_a: CL:0000234 ! phagocyte is_a: CL:0000255 ! eukaryotic cell relationship: RO:0002160 NCBITaxon:7742 ! only in taxon Vertebrata [Term] id: CL:0000521 name: fungal cell is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: RO:0002160 NCBITaxon:4751 ! only in taxon Fungi relationship: RO:0002160 NCBITaxon:4751 ! only in taxon Fungi [Term] id: CL:0000525 name: syncytiotrophoblast cell def: "A cell from the outer syncytial layer of the trophoblast of an early mammalian embryo, directly associated with the maternal blood supply. It secretes hCG in order to maintain progesterone secretion and sustain a pregnancy." [GOC:tfm, ISBN:0323052908] synonym: "syncytial trophoblast cell" EXACT [PMID:11787150] synonym: "syncytiotrophoblastic cell" EXACT [PMID:21733368] xref: FMA:83043 is_a: CL:0000228 ! multinucleate cell is_a: CL:0000351 ! trophoblast cell intersection_of: CL:0000351 ! trophoblast cell intersection_of: RO:0000053 PATO:0001908 ! has characteristic multinucleate relationship: BFO:0000050 UBERON:0000371 ! part of syncytiotrophoblast [Term] id: CL:0000526 name: afferent neuron def: "A neuron which conveys sensory information centrally from the periphery." [GOC:tfm, MESH:D009475] synonym: "input neuron" EXACT [] xref: FMA:87653 is_a: CL:0000540 ! neuron [Term] id: CL:0000527 name: efferent neuron def: "A neuron which sends impulses peripherally to activate muscles or secretory cells." [MESH:D009476] synonym: "output neuron" EXACT [] is_a: CL:0000540 ! neuron [Term] id: CL:0000540 name: neuron def: "The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system." [http://en.wikipedia.org/wiki/Neuron, MESH:D009474] synonym: "nerve cell" EXACT [] xref: BTO:0000938 xref: CALOHA:TS-0683 xref: FBbt:00005106 xref: FMA:54527 xref: VHOG:0001483 xref: WBbt:0003679 is_a: CL:0000393 ! electrically responsive cell is_a: CL:0000404 ! electrically signaling cell is_a: CL:0002319 ! neural cell relationship: RO:0002202 CL:0000031 {gci_filler="NCBITaxon:7742", gci_relation="RO:0002162", xref="https://github.com/obophenotype/cell-ontology/issues/757"} ! develops from neuroblast (sensu Vertebrata) relationship: RO:0002215 GO:0019226 ! capable of transmission of nerve impulse property_value: x_0.1:depiction "https://www.swissbiopics.org/api/image/Neuron_cells.svg" xsd:anyURI [Term] id: CL:0000542 name: lymphocyte def: "A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin." [GOC:add, ISBN:0683073696, ISBN:0781735149] xref: BTO:0000775 xref: CALOHA:TS-0583 xref: FMA:62863 xref: MESH:D008214 xref: VHOG:0001535 is_a: CL:0000842 ! mononuclear cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000738 ! leukocyte intersection_of: BFO:0000051 CL:0017500 ! has part neutrophillic cytoplasm intersection_of: BFO:0000051 GO:0000792 ! has part heterochromatin intersection_of: RO:0000053 PATO:0001407 ! has characteristic mononucleate intersection_of: RO:0000053 PATO:0040072 ! has characteristic high nuclear/cytoplasmic ratio disjoint_from: CL:0000766 ! myeloid leukocyte relationship: BFO:0000051 CL:0017500 ! has part neutrophillic cytoplasm relationship: BFO:0000051 GO:0000792 ! has part heterochromatin relationship: RO:0000053 PATO:0040072 ! has characteristic high nuclear/cytoplasmic ratio relationship: RO:0002202 CL:0000051 ! develops from common lymphoid progenitor [Term] id: CL:0000547 name: proerythroblast def: "An immature, nucleated erythrocyte occupying the stage of erythropoeisis that follows formation of erythroid progenitor cells. This cell is CD71-positive, has both a nucleus and a nucleolus, and lacks hematopoeitic lineage markers." [ISBN:0721601464, PMID:1638021] synonym: "rubriblast" EXACT [ISBN:0721601464] xref: FMA:83518 is_a: CL:0000764 ! erythroid lineage cell is_a: CL:0002242 ! nucleate cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000764 ! erythroid lineage cell intersection_of: BFO:0000051 CL:0017503 ! has part basophilic cytoplasm intersection_of: BFO:0000051 GO:0005730 ! has part nucleolus intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G intersection_of: RO:0000053 PATO:0002505 ! has characteristic nucleated intersection_of: RO:0000053 PATO:0040072 ! has characteristic high nuclear/cytoplasmic ratio intersection_of: RO:0002104 PR:000001945 ! has plasma membrane part transferrin receptor protein 1 relationship: BFO:0000051 CL:0017503 ! has part basophilic cytoplasm relationship: BFO:0000051 GO:0005730 ! has part nucleolus relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G relationship: RO:0000053 PATO:0040072 ! has characteristic high nuclear/cytoplasmic ratio relationship: RO:0002104 PR:000001945 ! has plasma membrane part transferrin receptor protein 1 relationship: RO:0002202 CL:0000038 ! develops from erythroid progenitor cell [Term] id: CL:0000549 name: basophilic erythroblast def: "A nucleated immature erythrocyte, having cytoplasm generally similar to that of the earlier proerythroblast but sometimes even more basophilic, and usually regular in outline. The nucleus is still relatively large, but the chromatin strands are thicker and more deeply staining, giving a coarser appearance; the nucleoli have disappeared. This cell is CD71-positive and lacks hematopoeitic lineage markers." [GOC:tfm, ISBN:0721601464] synonym: "basophilic normoblast" EXACT [ISBN:0721601464] synonym: "early erythroblast" EXACT [ISBN:0721601464] synonym: "early normoblast" EXACT [ISBN:0721601464] synonym: "prorubricyte" EXACT [ISBN:0721601464] xref: FMA:83505 is_a: CL:0000765 ! erythroblast is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000765 ! erythroblast intersection_of: BFO:0000051 CL:0017503 ! has part basophilic cytoplasm intersection_of: BFO:0000051 GO:0000792 ! has part heterochromatin intersection_of: RO:0002104 PR:000001945 ! has plasma membrane part transferrin receptor protein 1 relationship: BFO:0000051 CL:0017503 ! has part basophilic cytoplasm relationship: BFO:0000051 GO:0000792 ! has part heterochromatin relationship: RO:0002104 PR:000001945 ! has plasma membrane part transferrin receptor protein 1 [Term] id: CL:0000550 name: polychromatophilic erythroblast def: "A nucleated, immature erythrocyte in which the nucleus occupies a relatively smaller part of the cell than in its precursor, the basophilic erythroblast. The cytoplasm is beginning to acquire hemoglobin and thus is no longer a purely basophilic, but takes on acidophilic aspects, which becomes progressively more marked as the cell matures. The chromatin of the nucleus is arranged in coarse, deeply staining clumps. This cell is CD71-positive and lacks hematopoeitic lineage markers." [ISBN:0721601464] synonym: "intermediate erythroblast" EXACT [ISBN:0721601464] synonym: "intermediate normoblast" EXACT [ISBN:0721601464] synonym: "polychromatic erythroblast" EXACT [ISBN:0721601464] synonym: "polychromatic normoblast" EXACT [ISBN:0721601464] synonym: "polychromatophilic normoblast" EXACT [ISBN:0721601464] synonym: "rubricyte" EXACT [ISBN:0721601464] xref: FMA:83506 is_a: CL:0000765 ! erythroblast is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000765 ! erythroblast intersection_of: BFO:0000051 CL:0017504 ! has part polychromatophilic cytoplasm intersection_of: BFO:0000051 GO:0000792 ! has part heterochromatin intersection_of: RO:0002104 PR:000001945 ! has plasma membrane part transferrin receptor protein 1 relationship: BFO:0000051 CL:0017504 ! has part polychromatophilic cytoplasm relationship: BFO:0000051 GO:0000792 ! has part heterochromatin relationship: RO:0002104 PR:000001945 ! has plasma membrane part transferrin receptor protein 1 relationship: RO:0002202 CL:0000549 ! develops from basophilic erythroblast [Term] id: CL:0000552 name: orthochromatic erythroblast def: "The final stage of the nucleated, immature erythrocyte, before nuclear loss. Typically the cytoplasm is described as acidophilic, but it still shows a faint polychromatic tint. The nucleus is small and initially may still have coarse, clumped chromatin, as in its precursor, the polychromatophilic erythroblast, but ultimately it becomes pyknotic, and appears as a deeply staining, blue-black, homogeneous structureless mass. The nucleus is often eccentric and sometimes lobulated." [ISBN:0721601464] synonym: "acidophilic erythroblast" EXACT [ISBN:0721601464] synonym: "eosinophilic erythroblast" EXACT [ISBN:0721601464] synonym: "late erythoblast" EXACT [] synonym: "orthochromatic normoblast" EXACT [ISBN:0721601464] synonym: "pyknotic eto enrythroblast" EXACT [ISBN:0721601464] xref: FMA:84646 is_a: CL:0000765 ! erythroblast intersection_of: CL:0000765 ! erythroblast intersection_of: BFO:0000051 CL:0017502 ! has part acidophilic cytoplasm intersection_of: RO:0000056 GO:0030263 ! participates in apoptotic chromosome condensation relationship: BFO:0000051 CL:0017502 ! has part acidophilic cytoplasm relationship: RO:0000056 GO:0030263 ! participates in apoptotic chromosome condensation relationship: RO:0002202 CL:0000550 ! develops from polychromatophilic erythroblast [Term] id: CL:0000553 name: megakaryocyte progenitor cell def: "The earliest cytologically identifiable precursor in the thrombocytic series. This cell is capable of endomitosis and lacks expression of hematopoieitic lineage markers (lin-negative)." [GOC:dsd, GOC:tfm, ISBN:0721601464] synonym: "CFU-Meg" EXACT [PMID:11722431, PMID:12482498] synonym: "colony-forming unit-megakaryocyte" EXACT [] synonym: "Meg-CFC" EXACT [PMCID:PMC1794060] synonym: "megacaryoblast" EXACT [] synonym: "megacaryocyte progenitor cell" EXACT [] synonym: "megakaryoblast" EXACT [] synonym: "megakaryocytic progenitor cell" EXACT [PMID:12482498] synonym: "MkP" EXACT [PMID:21116988] xref: BTO:0001164 xref: CALOHA:TS-0610 xref: FMA:84235 xref: MESH:D055016 is_a: CL:0000763 ! myeloid cell is_a: CL:0000839 ! myeloid lineage restricted progenitor cell intersection_of: CL:0000839 ! myeloid lineage restricted progenitor cell intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G intersection_of: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) intersection_of: RO:0002215 GO:0007113 ! capable of endomitotic cell cycle intersection_of: RO:0002215 GO:0030219 ! capable of megakaryocyte differentiation relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G relationship: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) relationship: RO:0002202 CL:0000050 ! develops from megakaryocyte-erythroid progenitor cell relationship: RO:0002215 GO:0007113 ! capable of endomitotic cell cycle relationship: RO:0002215 GO:0030219 ! capable of megakaryocyte differentiation [Term] id: CL:0000556 name: megakaryocyte def: "A large hematopoietic cell (50 to 100 micron) with a lobated nucleus. Once mature, this cell undergoes multiple rounds of endomitosis and cytoplasmic restructuring to allow platelet formation and release." [http://en.wikipedia.org/wiki/Megakaryocyte, ISBN:0721601464, MESH:D008533, PMID:31043076] synonym: "megacaryocyte" EXACT [] synonym: "megalocaryocyte" EXACT [] synonym: "megalokaryocyte" EXACT [] xref: BTO:0000843 xref: CALOHA:TS-0611 xref: FMA:83555 is_a: CL:0000763 ! myeloid cell disjoint_from: CL:0000764 ! erythroid lineage cell relationship: RO:0000053 PATO:0001393 ! has characteristic euploid relationship: RO:0002202 CL:0000553 ! develops from megakaryocyte progenitor cell [Term] id: CL:0000558 name: reticulocyte def: "An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds." [GOC:add, GOC:tfm, PMID:15946868, PMID:2037622] xref: BTO:0001173 xref: CALOHA:TS-0864 xref: MESH:D012156 is_a: CL:0000764 ! erythroid lineage cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000764 ! erythroid lineage cell intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G intersection_of: RO:0002104 PR:000001945 ! has plasma membrane part transferrin receptor protein 1 intersection_of: RO:0002215 GO:0071971 ! capable of extracellular exosome assembly relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G relationship: RO:0002104 PR:000001945 ! has plasma membrane part transferrin receptor protein 1 relationship: RO:0002202 CL:0000552 ! develops from orthochromatic erythroblast relationship: RO:0002215 GO:0071971 ! capable of extracellular exosome assembly [Term] id: CL:0000562 name: nucleate erythrocyte def: "An erythrocyte having a nucleus." [GOC:add, GOc:tfm] is_a: CL:0000232 ! erythrocyte is_a: CL:0002242 ! nucleate cell intersection_of: CL:0000232 ! erythrocyte intersection_of: RO:0000053 PATO:0002505 ! has characteristic nucleated relationship: RO:0002202 CL:0002421 ! develops from nucleated reticulocyte [Term] id: CL:0000566 name: angioblastic mesenchymal cell def: "A mesenchymal stem cell capable of developing into blood vessel endothelium." [GOC:dsd, GOC:tfm, PMID:12768659] synonym: "angioblast" EXACT [] synonym: "chondroplast" EXACT [] is_a: CL:0000134 ! mesenchymal stem cell is_a: CL:0011026 ! progenitor cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000134 ! mesenchymal stem cell intersection_of: RO:0002104 PR:000001444 ! has plasma membrane part cadherin-5 intersection_of: RO:0002104 PR:000002112 ! has plasma membrane part vascular endothelial growth factor receptor 2 intersection_of: RO:0002104 PR:000016043 ! has plasma membrane part T-cell acute lymphocytic leukemia protein 1 relationship: RO:0002104 PR:000001444 ! has plasma membrane part cadherin-5 relationship: RO:0002104 PR:000002112 ! has plasma membrane part vascular endothelial growth factor receptor 2 relationship: RO:0002104 PR:000016043 ! has plasma membrane part T-cell acute lymphocytic leukemia protein 1 relationship: RO:0002202 CL:0000134 ! develops from mesenchymal stem cell [Term] id: CL:0000569 name: cardiac mesenchymal cell def: "A mesenchymal cell found in the developing heart and that develops into some part of the heart. These cells derive from intra- and extra-cardiac sources, including the endocardium, epicardium, neural crest, and second heart field." [PMID:18816864] is_a: CL:0008019 ! mesenchymal cell is_a: CL:2000073 ! migratory cardiac neural crest cell intersection_of: CL:0008019 ! mesenchymal cell intersection_of: RO:0002203 CL:0002494 ! develops into cardiocyte relationship: RO:0002203 CL:0002494 ! develops into cardiocyte [Term] id: CL:0000573 name: retinal cone cell def: "One of the two photoreceptor cell types in the vertebrate retina. In cones the photopigment is in invaginations of the cell membrane of the outer segment. Cones are less sensitive to light than rods, but they provide vision with higher spatial and temporal acuity, and the combination of signals from cones with different pigments allows color vision." [MESH:D017949] xref: BTO:0001036 xref: CALOHA:TS-0866 xref: FMA:67748 is_a: CL:0010009 ! camera-type eye photoreceptor cell relationship: RO:0002202 CL:0002672 ! develops from retinal progenitor cell [Term] id: CL:0000575 name: corneal epithelial cell def: "An epithelial cell of the cornea." [GOC:tfm] synonym: "epithelial cell of cornea" EXACT [FMA:70551] xref: BTO:0004298 xref: CALOHA:TS-0173 xref: FMA:70551 is_a: CL:0000076 ! squamous epithelial cell is_a: CL:0002159 ! general ecto-epithelial cell is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: CL:0000076 ! squamous epithelial cell intersection_of: BFO:0000050 UBERON:0001772 ! part of corneal epithelium relationship: BFO:0000050 UBERON:0001772 ! part of corneal epithelium [Term] id: CL:0000586 name: germ cell def: "The reproductive cell in multicellular organisms." [MESH:D005854] xref: BTO:0000535 xref: NCIT:C12597 xref: VHOG:0001534 xref: WBbt:0006796 is_a: CL:0000039 ! germ line cell relationship: RO:0002216 GO:0009566 ! capable of part of fertilization [Term] id: CL:0000593 name: androgen secreting cell def: "A steroid hormone secreting cell that secretes androgen." [GOC:tfm] is_a: CL:0000174 ! steroid hormone secreting cell intersection_of: CL:0000151 ! secretory cell intersection_of: RO:0002215 GO:0035935 ! capable of androgen secretion relationship: RO:0002215 GO:0035935 ! capable of androgen secretion [Term] id: CL:0000595 name: enucleate erythrocyte def: "An erythrocyte lacking a nucleus." [GOC:add, GOC:tfm] is_a: CL:0000225 ! anucleate cell is_a: CL:0000232 ! erythrocyte intersection_of: CL:0000232 ! erythrocyte intersection_of: RO:0000053 PATO:0001405 ! has characteristic anucleate relationship: RO:0002202 CL:0002422 ! develops from enucleated reticulocyte [Term] id: CL:0000604 name: retinal rod cell def: "One of the two photoreceptor cell types of the vertebrate retina. In rods the photopigment is in stacks of membranous disks separate from the outer cell membrane. Rods are more sensitive to light than cones, but rod mediated vision has less spatial and temporal resolution than cone vision." [MESH:D017948] xref: BTO:0001024 xref: CALOHA:TS-0870 xref: FMA:67747 is_a: CL:0010009 ! camera-type eye photoreceptor cell relationship: RO:0002202 CL:0002672 ! develops from retinal progenitor cell [Term] id: CL:0000622 name: acinar cell def: "A secretory cell that is grouped together with other cells of the same type to form grape shaped clusters known as acini (singular acinus)." [GOC:tfm, http://www.copewithcytokines.de] synonym: "acinic cell" EXACT [] synonym: "acinous cell" EXACT [] xref: FMA:83625 xref: MESH:D061354 is_a: CL:0000150 ! glandular epithelial cell is_a: CL:0000154 ! protein secreting cell relationship: BFO:0000050 UBERON:0009842 ! part of glandular acinus [Term] id: CL:0000630 name: supporting cell def: "A cell whose primary function is to support other cell types." [FB:ma, GOC:tfm] synonym: "supportive cell" EXACT [] xref: BTO:0002315 is_a: CL:0000000 ! cell [Term] id: CL:0000656 name: primary spermatocyte def: "A diploid cell that has derived from a spermatogonium and can subsequently begin meiosis and divide into two haploid secondary spermatocytes." [GOC:tfm, ISBN:0721662544] xref: BTO:0001115 xref: CALOHA:TS-2194 xref: FMA:72292 is_a: CL:0000017 ! spermatocyte is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000017 ! spermatocyte intersection_of: RO:0000053 PATO:0001394 ! has characteristic diploid intersection_of: RO:0002215 GO:0007140 ! capable of male meiotic nuclear division relationship: RO:0000053 PATO:0001394 ! has characteristic diploid relationship: RO:0002215 GO:0007140 ! capable of male meiotic nuclear division [Term] id: CL:0000657 name: secondary spermatocyte def: "One of the two haploid cells into which a primary spermatocyte divides, and which in turn gives origin to spermatids." [GOC:tfm, ISBN:0721662544] xref: BTO:0000709 xref: CALOHA:TS-2195 xref: FBbt:00004941 xref: FMA:72293 is_a: CL:0000017 ! spermatocyte is_a: CL:0000255 ! eukaryotic cell is_a: CL:0000413 ! haploid cell intersection_of: CL:0000017 ! spermatocyte intersection_of: RO:0000053 PATO:0001375 ! has characteristic haploid intersection_of: RO:0002215 GO:0007142 ! capable of male meiosis II relationship: RO:0002202 CL:0000656 ! develops from primary spermatocyte relationship: RO:0002215 GO:0007142 ! capable of male meiosis II [Term] id: CL:0000667 name: collagen secreting cell def: "An extracellular matrix secreting cell that secretes collagen." [GOC:tfm] is_a: CL:0000327 ! extracellular matrix secreting cell [Term] id: CL:0000670 name: primordial germ cell def: "A primordial germ cell is a diploid germ cell precursors that transiently exist in the embryo before they enter into close association with the somatic cells of the gonad and become irreversibly committed as germ cells." [GOC:tfm, PMID:1381289] synonym: "gonocyte" EXACT [] synonym: "primitive germ cell" EXACT [] xref: FMA:70567 is_a: CL:0000039 ! germ line cell is_a: CL:0000219 ! motile cell intersection_of: CL:0000039 ! germ line cell intersection_of: BFO:0000050 UBERON:0000922 ! part of embryo intersection_of: RO:0002215 GO:0048870 ! capable of cell motility relationship: BFO:0000050 UBERON:0000922 ! part of embryo [Term] id: CL:0000675 name: female gamete def: "A mature sexual reproductive cell of the female germline." [GOC:tfm] is_a: CL:0000021 ! female germ cell is_a: CL:0000300 ! gamete [Term] id: CL:0000680 name: muscle precursor cell def: "A non-terminally differentiated cell that is capable of developing into a muscle cell." [GOC:add] is_a: CL:0000055 ! non-terminally differentiated cell is_a: CL:0000255 ! eukaryotic cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0011115 ! precursor cell intersection_of: RO:0002203 CL:0000187 ! develops into muscle cell relationship: RO:0002202 CL:0000222 ! develops from mesodermal cell relationship: RO:0002203 CL:0000187 ! develops into muscle cell [Term] id: CL:0000696 name: PP cell def: "A cell that stores and secretes pancreatic polypeptide hormone." [GOC:tfm, JB:jb, PMID:15153415] synonym: "type F enteroendocrine cell" EXACT [] xref: FMA:62938 xref: FMA:83409 is_a: CL:0000164 ! enteroendocrine cell is_a: CL:0000167 ! peptide hormone secreting cell [Term] id: CL:0000710 name: neurecto-epithelial cell def: "Epithelial cells derived from neural plate and neural crest." [GOC:tfm] xref: BTO:0004301 xref: FMA:70557 is_a: CL:0000075 ! columnar/cuboidal epithelial cell is_a: CL:0002077 ! ecto-epithelial cell intersection_of: CL:0002077 ! ecto-epithelial cell intersection_of: RO:0002202 CL:0000133 ! develops from neurectodermal cell relationship: RO:0002202 CL:0000133 ! develops from neurectodermal cell [Term] id: CL:0000723 name: somatic stem cell def: "A stem cell that can give rise to cell types of the body other than those of the germ-line." [GO:0048103] xref: CALOHA:TS-2086 xref: MESH:D053687 is_a: CL:0000034 ! stem cell intersection_of: CL:0000034 ! stem cell intersection_of: RO:0002215 GO:0048103 ! capable of somatic stem cell division relationship: RO:0002215 GO:0048103 ! capable of somatic stem cell division [Term] id: CL:0000737 name: striated muscle cell def: "Muscle cell which has as its direct parts myofilaments organized into sarcomeres." [GOC:tfm, ISBN:0721662544] xref: BTO:0002916 xref: CALOHA:TS-2157 xref: FMA:86936 is_a: CL:0000187 ! muscle cell intersection_of: CL:0000187 ! muscle cell intersection_of: BFO:0000051 GO:0030017 ! has part sarcomere intersection_of: RO:0000053 PATO:0001410 ! has characteristic striated disjoint_from: CL:0008000 ! non-striated muscle cell relationship: BFO:0000051 GO:0030017 ! has part sarcomere relationship: RO:0000053 PATO:0001410 ! has characteristic striated [Term] id: CL:0000738 name: leukocyte def: "An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue." [GOC:add, GOC:tfm, ISBN:978-0-323-05290-0] synonym: "leucocyte" EXACT [] synonym: "white blood cell" EXACT [] xref: BTO:0000751 xref: CALOHA:TS-0549 xref: FMA:62852 xref: MESH:D007962 xref: NCIT:C12529 is_a: CL:0000219 ! motile cell is_a: CL:0000255 ! eukaryotic cell is_a: CL:0000988 ! hematopoietic cell is_a: CL:0002242 ! nucleate cell intersection_of: CL:0000988 ! hematopoietic cell intersection_of: RO:0000053 PATO:0002505 ! has characteristic nucleated intersection_of: RO:0002215 GO:0001667 ! capable of ameboidal-type cell migration relationship: BFO:0000050 UBERON:0002405 ! part of immune system relationship: RO:0002160 NCBITaxon:7742 ! only in taxon Vertebrata relationship: RO:0002202 CL:0000037 ! develops from hematopoietic stem cell relationship: RO:0002215 GO:0001667 ! capable of ameboidal-type cell migration [Term] id: CL:0000740 name: retinal ganglion cell def: "The set of neurons that receives neural inputs via bipolar, horizontal and amacrine cells. The axons of these cells make up the optic nerve." [GOC:dph] synonym: "gangliocyte" EXACT [] synonym: "ganglion cell of retina" EXACT [] xref: BTO:0001800 xref: FMA:67765 xref: MESH:D012165 is_a: CL:0000117 ! CNS neuron (sensu Vertebrata) relationship: RO:0002100 UBERON:0000966 ! has soma location retina [Term] id: CL:0000746 name: cardiac muscle cell def: "Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. In mammals, the contractile fiber resembles those of skeletal muscle but are only one third as large in diameter, are richer in sarcoplasm, and contain centrally located instead of peripheral nuclei." [GOC:mtg_cardiacconduct_nov11, GOC:tfm, ISBN:0323052908, PMID:22426062, PMID:4711263] synonym: "cardiac muscle fiber" EXACT [GO:0048739] synonym: "cardiac myocyte" EXACT [] synonym: "cardiomyocyte" EXACT [] synonym: "heart muscle cell" EXACT [] xref: BTO:0001539 xref: CALOHA:TS-0115 xref: FMA:14067 xref: MESH:D032383 is_a: CL:0000737 ! striated muscle cell is_a: CL:0002494 ! cardiocyte intersection_of: CL:0000187 ! muscle cell intersection_of: BFO:0000050 UBERON:0007100 ! part of primary circulatory organ intersection_of: BFO:0000051 GO:0030017 ! has part sarcomere intersection_of: RO:0000053 PATO:0002478 ! has characteristic transversely striated intersection_of: RO:0000056 GO:0060047 ! participates in heart contraction relationship: RO:0000053 PATO:0002478 ! has characteristic transversely striated relationship: RO:0000056 GO:0060047 ! participates in heart contraction relationship: RO:0002202 CL:0000513 ! develops from cardiac muscle myoblast [Term] id: CL:0000763 name: myeloid cell def: "A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage." [GOC:add] xref: BTO:0001441 xref: CALOHA:TS-0647 xref: MESH:D022423 is_a: CL:0000255 ! eukaryotic cell is_a: CL:0000988 ! hematopoietic cell intersection_of: CL:0000988 ! hematopoietic cell intersection_of: RO:0002202 CL:0000049 ! develops from common myeloid progenitor relationship: RO:0002202 CL:0000049 ! develops from common myeloid progenitor [Term] id: CL:0000764 name: erythroid lineage cell def: "A immature or mature cell in the lineage leading to and including erythrocytes." [GOC:add, GOC:tfm] synonym: "erythropoietic cell" EXACT [] xref: CALOHA:TS-0290 xref: FMA:62845 xref: FMA:83516 is_a: CL:0000763 ! myeloid cell [Term] id: CL:0000765 name: erythroblast def: "A nucleated precursor of an erythrocyte that lacks hematopoietic lineage markers." [GOC:add, ISBN:0721601464, PMID:18174176] synonym: "normoblast" EXACT [] xref: BTO:0001571 xref: CALOHA:TS-0289 xref: FMA:83504 xref: MESH:D004900 is_a: CL:0000764 ! erythroid lineage cell is_a: CL:0011026 ! progenitor cell intersection_of: CL:0000764 ! erythroid lineage cell intersection_of: BFO:0000051 GO:0005634 ! has part nucleus intersection_of: CL:4030045 GO:0005730 ! lacks_part nucleolus intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G intersection_of: RO:0002215 GO:0030218 ! capable of erythrocyte differentiation relationship: BFO:0000051 GO:0005634 ! has part nucleus relationship: CL:4030045 GO:0005730 ! lacks_part nucleolus relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G relationship: RO:0002202 CL:0000547 ! develops from proerythroblast relationship: RO:0002215 GO:0030218 ! capable of erythrocyte differentiation [Term] id: CL:0000766 name: myeloid leukocyte def: "A cell of the monocyte, granulocyte, or mast cell lineage." [GOC:add] is_a: CL:0000738 ! leukocyte is_a: CL:0000763 ! myeloid cell intersection_of: CL:0000738 ! leukocyte intersection_of: RO:0002202 CL:0000049 ! develops from common myeloid progenitor [Term] id: CL:0000783 name: multinucleated phagocyte def: "A phagocyte formed by the fusion of mononuclear phagocytes." [GOC:add, GOC:tfm] is_a: CL:0000228 ! multinucleate cell is_a: CL:0000518 ! phagocyte (sensu Vertebrata) intersection_of: CL:0000518 ! phagocyte (sensu Vertebrata) intersection_of: RO:0000053 PATO:0001908 ! has characteristic multinucleate [Term] id: CL:0000827 name: pro-T cell def: "A lymphoid progenitor cell of the T cell lineage, with some lineage specific marker expression, but not yet fully committed to the T cell lineage." [GOC:add, ISBN:0781735149] synonym: "pro-T lymphocyte" EXACT [] synonym: "progenitor T cell" EXACT [] is_a: CL:0000838 ! lymphoid lineage restricted progenitor cell intersection_of: CL:0000838 ! lymphoid lineage restricted progenitor cell intersection_of: RO:0002215 GO:0030217 ! capable of T cell differentiation relationship: RO:0002202 CL:0000051 ! develops from common lymphoid progenitor relationship: RO:0002215 GO:0030217 ! capable of T cell differentiation [Term] id: CL:0000837 name: hematopoietic multipotent progenitor cell def: "A hematopoietic multipotent progenitor cell is multipotent, but not capable of long-term self-renewal. These cells are characterized as lacking lineage cell surface markers and being CD34-positive in both mice and humans." [GOC:add, GOC:tfm, PMID:19022770] synonym: "hemopoietic progenitor cell" EXACT [] synonym: "MPP" EXACT [] xref: BTO:0000725 xref: CALOHA:TS-0448 is_a: CL:0000255 ! eukaryotic cell is_a: CL:0008001 ! hematopoietic precursor cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000988 ! hematopoietic cell intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 intersection_of: CL:4030046 PR:000001869 ! lacks_plasma_membrane_part interleukin-7 receptor subunit alpha intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G intersection_of: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) intersection_of: RO:0000053 PATO:0001402 ! has characteristic multipotent intersection_of: RO:0002104 PR:000001003 ! has plasma membrane part CD34 molecule disjoint_from: CL:0002032 ! hematopoietic oligopotent progenitor cell relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 relationship: CL:4030046 PR:000001869 ! lacks_plasma_membrane_part interleukin-7 receptor subunit alpha relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G relationship: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) relationship: RO:0000053 PATO:0001402 ! has characteristic multipotent relationship: RO:0002104 PR:000001003 ! has plasma membrane part CD34 molecule relationship: RO:0002202 CL:0000037 ! develops from hematopoietic stem cell [Term] id: CL:0000838 name: lymphoid lineage restricted progenitor cell def: "A progenitor cell restricted to the lymphoid lineage." [GOC:add, GOC:tfm] xref: BTO:0004731 xref: CALOHA:TS-2025 xref: FMA:70338 is_a: CL:0002031 ! hematopoietic lineage restricted progenitor cell is_a: CL:0011026 ! progenitor cell intersection_of: CL:0002031 ! hematopoietic lineage restricted progenitor cell intersection_of: RO:0002215 GO:0030098 ! capable of lymphocyte differentiation disjoint_from: CL:0000839 ! myeloid lineage restricted progenitor cell relationship: RO:0002215 GO:0030098 ! capable of lymphocyte differentiation [Term] id: CL:0000839 name: myeloid lineage restricted progenitor cell def: "A progenitor cell restricted to the myeloid lineage." [GOC:add, GOC:tfm, PMID:19022770] xref: BTO:0004730 xref: CALOHA:TS-2099 xref: FMA:70339 is_a: CL:0002031 ! hematopoietic lineage restricted progenitor cell is_a: CL:0011026 ! progenitor cell intersection_of: CL:0002031 ! hematopoietic lineage restricted progenitor cell intersection_of: RO:0002215 GO:0030099 ! capable of myeloid cell differentiation relationship: RO:0002215 GO:0030099 ! capable of myeloid cell differentiation [Term] id: CL:0000842 name: mononuclear cell def: "A leukocyte with a single non-segmented nucleus in the mature form." [GOC:add] synonym: "mononuclear leukocyte" EXACT [] xref: BTO:0000878 xref: CALOHA:TS-0768 xref: FMA:86713 is_a: CL:0000226 ! single nucleate cell is_a: CL:0000738 ! leukocyte intersection_of: CL:0000738 ! leukocyte intersection_of: RO:0000053 PATO:0001407 ! has characteristic mononucleate [Term] id: CL:0000850 name: serotonergic neuron def: "A neuron that releases serotonin as a neurotransmitter." [SANBI:mhl] synonym: "5-HT neuron" EXACT [] synonym: "5-hydroxytryptamine neuron" EXACT [] xref: FBbt:00005133 xref: MESH:D059326 xref: WBbt:0006837 is_a: CL:0000458 ! serotonin secreting cell is_a: CL:0000540 ! neuron intersection_of: CL:0000540 ! neuron intersection_of: RO:0002215 GO:0060096 ! capable of serotonin secretion, neurotransmission relationship: RO:0002215 GO:0060096 ! capable of serotonin secretion, neurotransmission [Term] id: CL:0000988 name: hematopoietic cell def: "A cell of a hematopoietic lineage." [GO_REF:0000031, GOC:add] synonym: "haematopoietic cell" EXACT [] synonym: "haemopoietic cell" EXACT [] synonym: "hemopoietic cell" EXACT [] xref: BTO:0000574 xref: CALOHA:TS-2017 xref: FMA:70366 xref: FMA:83598 is_a: CL:0000000 ! cell [Term] id: CL:0001035 name: bone cell def: "A connective tissue cell found in bone." [GO_REF:0000034, GOC:add] is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: BFO:0000050 UBERON:0001474 ! part of bone element relationship: BFO:0000050 UBERON:0001474 ! part of bone element creation_date: 2011-11-16T04:28:16Z [Term] id: CL:0001060 name: hematopoietic oligopotent progenitor cell, lineage-negative def: "A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities. Cell lacks hematopoeitic lineage markers." [GOC:tfm, PMID:19022770] is_a: CL:0002032 ! hematopoietic oligopotent progenitor cell intersection_of: CL:0002032 ! hematopoietic oligopotent progenitor cell intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G intersection_of: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) intersection_of: RO:0000053 PATO:0001401 ! has characteristic oligopotent relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G relationship: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) creation_date: 2010-01-06T03:43:27Z [Term] id: CL:0001066 name: erythroid progenitor cell, mammalian def: "A progenitor cell committed to the erythroid lineage. This cell is ter119-positive but lacks expression of other hematopoietic lineage markers (lin-negative)." [GOC:add, ISBN:0721601464] xref: BTO:0004911 is_a: CL:0000038 ! erythroid progenitor cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000038 ! erythroid progenitor cell intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G intersection_of: RO:0002104 PR:000001945 ! has plasma membrane part transferrin receptor protein 1 intersection_of: RO:0002215 GO:0030218 ! capable of erythrocyte differentiation relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G relationship: RO:0002104 PR:000001945 ! has plasma membrane part transferrin receptor protein 1 relationship: RO:0002215 GO:0030218 ! capable of erythrocyte differentiation [Term] id: CL:0002031 name: hematopoietic lineage restricted progenitor cell def: "A hematopoietic progenitor cell that is capable of developing into only one lineage of hematopoietic cells." [GOC:tfm, PMID:19022770] is_a: CL:0000255 ! eukaryotic cell is_a: CL:0008001 ! hematopoietic precursor cell intersection_of: CL:0000988 ! hematopoietic cell intersection_of: RO:0000053 PATO:0001400 ! has characteristic unipotent disjoint_from: CL:0002032 ! hematopoietic oligopotent progenitor cell relationship: RO:0000053 PATO:0001400 ! has characteristic unipotent relationship: RO:0002202 CL:0002032 ! develops from hematopoietic oligopotent progenitor cell creation_date: 2010-01-06T03:43:20Z [Term] id: CL:0002032 name: hematopoietic oligopotent progenitor cell def: "A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities." [GOC:tfm, https://orcid.org/0000-0001-5208-3432, PMID:19022770] is_a: CL:0000255 ! eukaryotic cell is_a: CL:0008001 ! hematopoietic precursor cell intersection_of: CL:0000988 ! hematopoietic cell intersection_of: RO:0000053 PATO:0001401 ! has characteristic oligopotent relationship: RO:0000053 PATO:0001401 ! has characteristic oligopotent relationship: RO:0002202 CL:0000837 ! develops from hematopoietic multipotent progenitor cell creation_date: 2010-01-06T03:43:27Z [Term] id: CL:0002064 name: pancreatic acinar cell def: "A secretory cell found in pancreatic acini that secretes digestive enzymes and mucins. This cell is a typical zymogenic cell, have a basal nucleus and basophilic cytoplasm consisting of regular arrays of granular endoplasmic reticulum with mitochondria and dense secretory granules." [GOC:tfm, http://www.copewithcytokines.de/cope.cgi?key=pancreatic%20acinar%20cells, ISBN:0517223651, PMID:20395539] synonym: "acinar cell of pancreas" EXACT [] xref: BTO:0000028 xref: CALOHA:TS-0737 xref: FMA:63032 is_a: CL:0000622 ! acinar cell is_a: CL:1001599 ! pancreas exocrine glandular cell intersection_of: CL:0000622 ! acinar cell intersection_of: BFO:0000050 UBERON:0001263 ! part of pancreatic acinus relationship: BFO:0000050 UBERON:0001263 ! part of pancreatic acinus relationship: BFO:0000051 GO:0042589 ! has part zymogen granule membrane creation_date: 2010-06-24T03:16:29Z [Term] id: CL:0002067 name: type A enteroendocrine cell def: "An enteroendocrine cell that produces glucagon." [GOC:tfm, ISBN:0412046911] xref: FMA:62939 is_a: CL:0000164 ! enteroendocrine cell is_a: CL:0000170 ! glucagon secreting cell intersection_of: CL:0000164 ! enteroendocrine cell intersection_of: RO:0002215 GO:0070091 ! capable of glucagon secretion creation_date: 2010-09-10T10:48:54Z [Term] id: CL:0002068 name: Purkinje myocyte def: "Specialized cardiac myocyte that is subendocardially interspersed with the regular cardiac muscle cell. They are uninucleate cylindrical cells, associated end-to-end in long rows, continue from the node to the atrioventricular bundle; relatively short compared to ordinary myocytes but are nearly twice their diameter." [FMA:0412046911, GOC:tfm, PMID:19939742] synonym: "myocytus conducens cardiacus" EXACT [] synonym: "Purkinje cell fiber" EXACT [] synonym: "Purkinje muscle cell" EXACT [] xref: BTO:0001032 xref: FMA:14146 is_a: CL:0002086 ! specialized cardiac myocyte creation_date: 2010-06-28T08:36:15Z [Term] id: CL:0002072 name: nodal myocyte def: "A specialized cardiac myocyte in the sinoatrial and atrioventricular nodes. The cell is slender and fusiform confined to the nodal center, circumferentially arranged around the nodal artery." [FMA:67101, GOC:tfm] synonym: "cardiac pacemaker cell" EXACT [GOC:pr] synonym: "myocytus nodalis" EXACT [] synonym: "P cell" EXACT [] xref: BTO:0004190 xref: FMA:67101 is_a: CL:0002086 ! specialized cardiac myocyte creation_date: 2010-06-29T11:41:37Z [Term] id: CL:0002073 name: transitional myocyte def: "Specialized cardiac myocyte which is in the internodal tract and atrioventricular node. The cell is more slender than ordinary atrial myocytes and has more myofibrils than nodal myocytes." [FMA:67142, GOC:tfm] xref: FMA:67142 is_a: CL:0002086 ! specialized cardiac myocyte creation_date: 2010-06-29T02:39:32Z [Term] id: CL:0002074 name: myocardial endocrine cell def: "The myoendocrine cellis a specialized myocyte localized mainly in the right and left atrial appendages, and also scattered within other areas of the atria and along the conductive system in the ventricular septum. The most conspicuous feature distinguishing myoendocrine cells from other atrial myoctyes is the presence of membane-bounded secretory granules (these granules contain precursor of cardiodilatins or atrial natriuretic polypeptides)." [FMA:67111, GOC:tfm] xref: FMA:67111 is_a: CL:0000163 ! endocrine cell is_a: CL:0002086 ! specialized cardiac myocyte creation_date: 2010-06-29T11:50:47Z [Term] id: CL:0002076 name: endo-epithelial cell def: "An epithelial cell derived from endoderm." [FMA:69075, GOC:tfm] xref: FMA:69075 is_a: CL:0000066 ! epithelial cell is_a: UBERON:0004119 ! endoderm-derived structure relationship: RO:0002202 CL:0000223 ! develops from endodermal cell creation_date: 2010-06-29T03:38:14Z [Term] id: CL:0002077 name: ecto-epithelial cell def: "An epithelial cell derived from ectoderm." [FMA:69074, GOC:tfm] xref: FMA:69074 is_a: CL:0000066 ! epithelial cell is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:0000066 ! epithelial cell intersection_of: RO:0002202 CL:0000221 ! develops from ectodermal cell relationship: RO:0002202 CL:0000221 ! develops from ectodermal cell property_value: skos:prefLabel "ecto-epithelial cell" xsd:string creation_date: 2010-06-29T03:38:22Z [Term] id: CL:0002078 name: meso-epithelial cell def: "Epithelial cell derived from mesoderm or mesenchyme." [FMA:69076, GOC:tfm] synonym: "epithelial mesenchymal cell" EXACT [] xref: FMA:69076 is_a: CL:0000066 ! epithelial cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000066 ! epithelial cell intersection_of: RO:0002202 CL:0000222 ! develops from mesodermal cell relationship: RO:0002202 CL:0000222 ! develops from mesodermal cell creation_date: 2010-06-29T03:49:14Z [Term] id: CL:0002079 name: pancreatic ductal cell def: "Epithelial cell found in the ducts of the pancreas. This cell type contributes to the high luminal pH." [FMA:63099, GOC:tfm, PMID:14740223] xref: FMA:63099 is_a: CL:0000069 ! branched duct epithelial cell is_a: CL:1001433 ! epithelial cell of exocrine pancreas intersection_of: CL:0000083 ! epithelial cell of pancreas intersection_of: BFO:0000050 UBERON:0001064 ! part of ventral pancreatic duct intersection_of: RO:0002215 GO:0015106 ! capable of bicarbonate transmembrane transporter activity relationship: BFO:0000050 UBERON:0001064 ! part of ventral pancreatic duct relationship: RO:0002215 GO:0015106 ! capable of bicarbonate transmembrane transporter activity creation_date: 2010-06-30T08:49:43Z [Term] id: CL:0002080 name: pancreatic centro-acinar cell def: "A cubodial epithelial cell that is continuous with the lining of intercalated ducts that drain the acinus. This cell type secretes a high pH solution to aid in activation of zymogens, and can differentiate into endocrine and exocrine pancreatic cell types." [GOC:tfm, PMID:12142741, PMID:20018761, PMID:8185160] synonym: "centroacinar cell of Langerhans" EXACT [] synonym: "pancreatic centroacinar cell" EXACT [] xref: FMA:62455 is_a: CL:1001433 ! epithelial cell of exocrine pancreas intersection_of: CL:0000083 ! epithelial cell of pancreas intersection_of: BFO:0000050 UBERON:0001263 ! part of pancreatic acinus intersection_of: RO:0002215 GO:0015106 ! capable of bicarbonate transmembrane transporter activity relationship: BFO:0000050 UBERON:0001263 ! part of pancreatic acinus relationship: RO:0002215 GO:0015106 ! capable of bicarbonate transmembrane transporter activity creation_date: 2010-06-30T08:49:52Z [Term] id: CL:0002086 name: specialized cardiac myocyte def: "A cardiac myocyte that is an excitable cells in the myocardium, specifically in the conducting system of heart." [FMA:67968, GOC:tfm] xref: FMA:67968 is_a: CL:0000746 ! cardiac muscle cell creation_date: 2010-07-21T01:33:38Z [Term] id: CL:0002087 name: nongranular leukocyte def: "A leukocyte that lacks granules." [GOC:tfm] synonym: "agranular leukocyte" EXACT [] xref: FMA:62855 is_a: CL:0000738 ! leukocyte intersection_of: CL:0000738 ! leukocyte intersection_of: CL:4030045 GO:0030141 ! lacks_part secretory granule relationship: CL:4030045 GO:0030141 ! lacks_part secretory granule creation_date: 2010-07-22T11:30:33Z [Term] id: CL:0002088 name: interstitial cell of Cajal def: "This is a cell found in the gastrointestinal tract of mammals and serves as a pacemaker that triggers gut contraction. ICCs mediate inputs from the enteric nervous system to smooth muscle cells and are thought to be the cells from which gastrointestinal stromal tumors (GISTs) arise." [GOC:tfm, PMID:16460275, PMID:19520112] synonym: "ICC" EXACT [] synonym: "intestinal pacemaker cell" EXACT [GOC:pr] xref: BTO:0003914 xref: FMA:86573 is_a: CL:0000710 ! neurecto-epithelial cell intersection_of: CL:0000710 ! neurecto-epithelial cell intersection_of: RO:0002215 GO:0043134 ! capable of regulation of hindgut contraction relationship: RO:0002215 GO:0043134 ! capable of regulation of hindgut contraction creation_date: 2010-07-22T03:26:00Z [Term] id: CL:0002092 name: bone marrow cell def: "A cell found in the bone marrow. This can include fibroblasts, macrophages, adipocytes, osteoblasts, osteoclasts, endothelial cells and hematopoietic cells." [GOC:tfm, ISBN:0618947256] xref: BTO:0004850 xref: FMA:83621 xref: MESH:D001854 is_a: CL:0001035 ! bone cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0001035 ! bone cell intersection_of: BFO:0000050 UBERON:0002371 ! part of bone marrow relationship: BFO:0000050 UBERON:0002371 ! part of bone marrow creation_date: 2010-07-22T04:48:15Z [Term] id: CL:0002095 name: hilus cell of ovary def: "A cell in the hilum of the ovary that produces androgens." [GOC:tfm, ISBN:068340007X] synonym: "hilar cell of ovary" EXACT [] xref: FMA:18710 is_a: CL:0000593 ! androgen secreting cell is_a: CL:0002132 ! stromal cell of ovary creation_date: 2010-08-23T11:18:18Z [Term] id: CL:0002132 name: stromal cell of ovary def: "A stomal cell of the ovary" [GOC:tfm] synonym: "ovarian stromal cell" EXACT [GOC:cjm] xref: FMA:72299 is_a: CL:0000499 ! stromal cell intersection_of: CL:0000499 ! stromal cell intersection_of: BFO:0000050 UBERON:0000992 ! part of ovary relationship: BFO:0000050 UBERON:0000992 ! part of ovary creation_date: 2010-08-23T12:10:31Z [Term] id: CL:0002139 name: endothelial cell of vascular tree def: "An endothelial cell of the vascular tree, which includes blood vessels and lymphatic vessels." [GOC:dsd, GOC:tfm, PMID:12768659] synonym: "vascular endothelial cell" EXACT [] xref: BTO:0001854 xref: CALOHA:TS-1106 xref: FMA:67755 is_a: CL:0000115 ! endothelial cell creation_date: 2010-08-24T02:06:40Z [Term] id: CL:0002144 name: capillary endothelial cell def: "An endothelial cell found in capillaries." [GOC:tfm] xref: BTO:0004956 xref: CALOHA:TS-0112 xref: FMA:67756 is_a: CL:2000008 ! microvascular endothelial cell intersection_of: CL:0000071 ! blood vessel endothelial cell intersection_of: BFO:0000050 UBERON:0001915 ! part of endothelium of capillary relationship: BFO:0000050 UBERON:0001915 ! part of endothelium of capillary creation_date: 2010-08-24T10:15:00Z [Term] id: CL:0002149 name: epithelial cell of uterus def: "An epithelial cell of the uterus." [GOC:tfm] xref: FMA:256161 is_a: CL:0002076 ! endo-epithelial cell intersection_of: CL:0002076 ! endo-epithelial cell intersection_of: BFO:0000050 UBERON:0000995 ! part of uterus relationship: BFO:0000050 UBERON:0000995 ! part of uterus creation_date: 2010-08-24T10:45:54Z [Term] id: CL:0002159 name: general ecto-epithelial cell def: "Epithelial cells derived from general body ectoderm and ectoderm placodes." [GOC:tfm] xref: FMA:70556 is_a: CL:0002077 ! ecto-epithelial cell creation_date: 2010-08-26T08:31:08Z [Term] id: CL:0002178 name: epithelial cell of stomach def: "An epithelial cell found in the lining of the stomach." [GOC:tfm] xref: FMA:62948 is_a: CL:0002251 ! epithelial cell of alimentary canal intersection_of: CL:0000066 ! epithelial cell intersection_of: BFO:0000050 UBERON:0000945 ! part of stomach relationship: BFO:0000050 UBERON:0000945 ! part of stomach creation_date: 2010-08-25T03:22:08Z [Term] id: CL:0002180 name: mucous cell of stomach def: "A mucous cell in the epithelium of the stomach." [GOC:tfm] xref: FMA:63464 is_a: CL:0002659 ! glandular cell of stomach intersection_of: CL:0002178 ! epithelial cell of stomach intersection_of: BFO:0000050 UBERON:0001199 ! part of mucosa of stomach relationship: BFO:0000050 UBERON:0001199 ! part of mucosa of stomach creation_date: 2010-08-25T03:38:51Z [Term] id: CL:0002183 name: stem cell of gastric gland def: "A stomach epithelial cell that is olumnar in form with a few short apical microvilli; relatively undifferentiated mitotic cell from which other types of gland are derived; few in number, situated in the isthmus region of the gland and base of the gastric pit." [GOC:tfm, ISBN:0517223651] xref: FMA:62953 is_a: CL:0000048 ! multi fate stem cell is_a: CL:0000152 ! exocrine cell is_a: CL:0002180 ! mucous cell of stomach intersection_of: CL:0000048 ! multi fate stem cell intersection_of: BFO:0000050 UBERON:0000325 ! part of gastric gland relationship: BFO:0000050 UBERON:0000325 ! part of gastric gland creation_date: 2010-08-25T03:57:08Z [Term] id: CL:0002195 name: hepatic stem cell def: "A stem cell that can give rise to the cells of the liver. The term usually refers to the self-renewing pool of hepatocyte precursors in the adult liver (differently from 'hepatoblast', often used for fetal precursors of hepatocytes)." [GOC:tfm, PMID:26798363] xref: FMA:86577 is_a: CL:0000048 ! multi fate stem cell is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: CL:0000048 ! multi fate stem cell intersection_of: BFO:0000050 UBERON:0002107 ! part of liver relationship: BFO:0000050 UBERON:0002107 ! part of liver creation_date: 2010-08-30T02:00:42Z [Term] id: CL:0002222 name: vertebrate lens cell def: "A cell comprising the transparent, biconvex body separating the posterior chamber and vitreous body, and constituting part of the refracting mechanism of the mammalian eye." [GOC:tfm, ISBN:0721662544] xref: FMA:70950 is_a: CL:0000066 ! epithelial cell is_a: CL:0000306 ! crystallin accumulating cell is_a: UBERON:0004121 ! ectoderm-derived structure relationship: BFO:0000050 UBERON:0000965 ! part of lens of camera-type eye creation_date: 2010-09-07T10:38:03Z [Term] id: CL:0002224 name: lens epithelial cell def: "A cell of the cuboidal epithelium that covers the lens. The cells of the lens epithelium regulate most of the homeostatic functions of the lens. As ions, nutrients, and liquid enter the lens from the aqueous humor, Na+/K+ ATPase pumps in the lens epithelial cells pump ions out of the lens to maintain appropriate lens osmolarity and volume, with equatorially positioned lens epithelium cells contributing most to this current. The activity of the Na+/K+ ATPases keeps water and current flowing through the lens from the poles and exiting through the equatorial regions. The cells of the lens epithelium also serve as the progenitors for new lens fibers. It constantly lays down fibers in the embryo, fetus, infant, and adult, and continues to lay down fibers for lifelong growth." [GOC:tfm, http://en.wikipedia.org/wiki/Lens_%28anatomy%29#Lens_epithelium, ISBN:0721662544] xref: FMA:67559 is_a: CL:0000075 ! columnar/cuboidal epithelial cell is_a: CL:0002222 ! vertebrate lens cell intersection_of: CL:0000075 ! columnar/cuboidal epithelial cell intersection_of: BFO:0000050 UBERON:0001803 ! part of epithelium of lens relationship: BFO:0000050 UBERON:0001803 ! part of epithelium of lens creation_date: 2010-09-07T10:45:47Z [Term] id: CL:0002240 name: marrow fibroblast def: "A fibroblast in the bone marrow." [GOC:tfm] xref: FMA:84377 is_a: CL:0000057 ! fibroblast is_a: CL:0002092 ! bone marrow cell intersection_of: CL:0000057 ! fibroblast intersection_of: BFO:0000050 UBERON:0002371 ! part of bone marrow creation_date: 2010-09-07T02:25:18Z [Term] id: CL:0002241 name: pulmonary interstitial fibroblast def: "A fibroblasts found in interstitial spaces in the pulmonary tract. Greater numbers of these cells are found in idiopathic pulmonary fibrosis." [GOC:tfm] synonym: "pulmonary myofibroblast" EXACT [] synonym: "pulmonary septal cell" EXACT [] xref: FMA:84467 is_a: CL:0000057 ! fibroblast is_a: CL:4030031 ! interstitial cell intersection_of: CL:0000057 ! fibroblast intersection_of: BFO:0000050 UBERON:0001004 ! part of respiratory system intersection_of: BFO:0000050 UBERON:0005169 ! part of interstitial tissue relationship: BFO:0000050 UBERON:0001004 ! part of respiratory system creation_date: 2010-09-07T02:29:38Z [Term] id: CL:0002242 name: nucleate cell def: "A cell containing at least one nucleus." [GOC:tfm] xref: FMA:67513 is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: RO:0000053 PATO:0002505 ! has characteristic nucleated relationship: RO:0000053 PATO:0002505 ! has characteristic nucleated creation_date: 2010-09-07T03:32:33Z [Term] id: CL:0002243 name: smooth muscle cell of sphincter of pupil def: "A circular smooth muscle cell of the iris, innervated by the ciliary nerves (parasympathetic), and acting to contract the pupil. This muscle cell derives from neuroectoderm. This smooth muscle cell results from transformation of epithelial cells to smooth muscle cells." [GOC:tfm, ISBN:0721662544, ISBN:0721694128] synonym: "smooth muscle fiber of sphincter of pupil" EXACT [] xref: FMA:70611 is_a: CL:0000358 ! sphincter associated smooth muscle cell is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:0000192 ! smooth muscle cell intersection_of: BFO:0000050 UBERON:0001607 ! part of sphincter pupillae relationship: BFO:0000050 UBERON:0001607 ! part of sphincter pupillae relationship: RO:0002202 CL:0000133 ! develops from neurectodermal cell creation_date: 2010-09-08T08:53:42Z [Term] id: CL:0002246 name: peripheral blood stem cell def: "A hematopoeitic stem cell found in the blood. Normally found in very limited numbers in the peripheral circulation (less than 0.1% of all nucleated cells)." [GOC:tfm] synonym: "PBSC" EXACT [] xref: BTO:0002669 xref: FMA:86711 xref: MESH:D000072916 is_a: CL:0000037 ! hematopoietic stem cell is_a: CL:0000080 ! circulating cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000037 ! hematopoietic stem cell intersection_of: BFO:0000050 UBERON:0000178 ! part of blood relationship: BFO:0000050 UBERON:0000178 ! part of blood creation_date: 2010-09-07T03:57:09Z [Term] id: CL:0002251 name: epithelial cell of alimentary canal def: "An epithelial cell of the musculomembranous digestive tube extending from the mouth to the anus." [GOC:tfm, ISBN:0721662544] is_a: CL:0002076 ! endo-epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: BFO:0000050 UBERON:0001555 ! part of digestive tract relationship: BFO:0000050 UBERON:0001555 ! part of digestive tract creation_date: 2010-09-08T09:26:53Z [Term] id: CL:0002252 name: epithelial cell of esophagus def: "An epithelial cell of the esophagus." [GOC:tfm] xref: FMA:63071 is_a: CL:0002251 ! epithelial cell of alimentary canal intersection_of: CL:0000066 ! epithelial cell intersection_of: BFO:0000050 UBERON:0001043 ! part of esophagus relationship: BFO:0000050 UBERON:0001043 ! part of esophagus creation_date: 2010-09-08T09:28:20Z [Term] id: CL:0002253 name: epithelial cell of large intestine def: "An epithelial cell of the large intestine." [GOC:tfm] xref: BTO:0004297 xref: FMA:256157 is_a: CL:0002563 ! intestinal epithelial cell intersection_of: CL:0002563 ! intestinal epithelial cell intersection_of: BFO:0000050 UBERON:0000059 ! part of large intestine relationship: BFO:0000050 UBERON:0000059 ! part of large intestine creation_date: 2010-09-08T09:28:22Z [Term] id: CL:0002254 name: epithelial cell of small intestine def: "An epithelial cell of the small intestine." [GOC:tfm] xref: FMA:256159 is_a: CL:0002563 ! intestinal epithelial cell intersection_of: CL:0002563 ! intestinal epithelial cell intersection_of: BFO:0000050 UBERON:0002108 ! part of small intestine relationship: BFO:0000050 UBERON:0002108 ! part of small intestine creation_date: 2010-09-08T09:41:46Z [Term] id: CL:0002255 name: stromal cell of endometrium def: "A stromal cell of the endometrium that is fibroblastic in appearance. During decidualization this cell may differentiate into a decidual stromal cell." [https://doi.org/10.1038/s41591-020-1040-z, PMID:11331626, PMID:30013421, PMID:30309298, Wiki:Decidualization&oldid=908981933#Endometrial_stromal_cells_(ESCs)] synonym: "endometrial stromal cell" EXACT [] synonym: "endometrial stromal fibroblast" EXACT [PMID:30309298] xref: CALOHA:TS-1266 xref: FMA:86490 is_a: CL:0000499 ! stromal cell intersection_of: CL:0000499 ! stromal cell intersection_of: BFO:0000050 UBERON:0001295 ! part of endometrium relationship: BFO:0000050 UBERON:0002337 ! part of endometrial stroma relationship: RO:0002388 CL:2000002 ! has potential to directly develop into decidual cell creation_date: 2010-09-08T09:50:04Z [Term] id: CL:0002262 name: endothelial cell of sinusoid def: "An endothelial cell that lines any of the venous cavities through which blood passes in various glands and organs such as the spleen and liver." [GOC:tfm, ISBN:0618947256] xref: FMA:63134 is_a: CL:0000115 ! endothelial cell intersection_of: CL:0000115 ! endothelial cell intersection_of: BFO:0000050 UBERON:0003909 ! part of sinusoid relationship: BFO:0000050 UBERON:0003909 ! part of sinusoid creation_date: 2010-09-14T10:57:26Z [Term] id: CL:0002264 name: type A cell of stomach def: "A type of enteroendocrine cell found in the stomach that secretes glucagon." [GOC:tfm] xref: FMA:83411 is_a: CL:0002067 ! type A enteroendocrine cell is_a: CL:0002659 ! glandular cell of stomach intersection_of: CL:0002067 ! type A enteroendocrine cell intersection_of: BFO:0000050 UBERON:0000945 ! part of stomach creation_date: 2010-09-10T10:54:42Z [Term] id: CL:0002265 name: type D cell of colon def: "A D cell located in the colon." [GOC:tfm] synonym: "colon D-cell" EXACT [] synonym: "colonic delta cell" EXACT [] synonym: "delta cell of colon" EXACT [] xref: FMA:268744 is_a: CL:0000502 ! type D enteroendocrine cell is_a: CL:0009042 ! enteroendocrine cell of colon intersection_of: CL:0000502 ! type D enteroendocrine cell intersection_of: BFO:0000050 UBERON:0001155 ! part of colon creation_date: 2010-09-10T11:37:35Z [Term] id: CL:0002266 name: type D cell of small intestine def: "A type D cell of the small intestine." [GOC:tfm] synonym: "delta cell of small intestine" EXACT [] synonym: "small intestine D-cell" EXACT [] synonym: "small intestine delta cell" EXACT [] xref: FMA:268736 is_a: CL:0000502 ! type D enteroendocrine cell is_a: CL:0009006 ! enteroendocrine cell of small intestine intersection_of: CL:0000502 ! type D enteroendocrine cell intersection_of: BFO:0000050 UBERON:0002108 ! part of small intestine creation_date: 2010-09-10T01:34:22Z [Term] id: CL:0002267 name: type D cell of stomach def: "A type D cell found in the stomach." [GOC:tfm] synonym: "delta cell of stomach" EXACT [] synonym: "stomach D-cell" EXACT [] synonym: "stomach delta cell" EXACT [] xref: FMA:83410 is_a: CL:0000502 ! type D enteroendocrine cell is_a: CL:0002659 ! glandular cell of stomach intersection_of: CL:0000502 ! type D enteroendocrine cell intersection_of: BFO:0000050 UBERON:0000945 ! part of stomach creation_date: 2010-09-10T01:36:03Z [Term] id: CL:0002275 name: pancreatic PP cell def: "A PP cell located in the islets of the pancreas." [GOC:tfm] synonym: "pancreatic polypeptide-secreting cell" EXACT [] synonym: "PP cell of pancreatic islet" EXACT [] synonym: "PP-cell of pancreatic islet" EXACT [] xref: BTO:0000805 xref: FMA:70588 xref: MESH:D050418 is_a: CL:0000696 ! PP cell is_a: CL:0008024 ! pancreatic endocrine cell intersection_of: CL:0000696 ! PP cell intersection_of: BFO:0000050 UBERON:0000006 ! part of islet of Langerhans intersection_of: BFO:0000050 UBERON:0001264 ! part of pancreas relationship: BFO:0000050 UBERON:0000006 ! part of islet of Langerhans creation_date: 2010-09-10T03:30:31Z [Term] id: CL:0002308 name: epithelial cell of skin gland def: "An epithelial cell of a skin gland." [GOC:tfm] synonym: "epithelial cell of gland of skin" EXACT [] xref: FMA:70657 is_a: CL:0002159 ! general ecto-epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: BFO:0000050 UBERON:0002419 ! part of skin gland relationship: BFO:0000050 UBERON:0002419 ! part of skin gland creation_date: 2010-09-14T12:00:07Z [Term] id: CL:0002319 name: neural cell def: "A cell that is part of the nervous system." [GOC:tfm, ISBN:0618947256] xref: CALOHA:TS-2040 xref: FMA:70333 is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: BFO:0000050 UBERON:0001016 ! part of nervous system relationship: BFO:0000050 UBERON:0001016 ! part of nervous system creation_date: 2010-09-15T01:34:57Z [Term] id: CL:0002320 name: connective tissue cell def: "A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone." [GOC:tfm, ISBN:0618947256] xref: CALOHA:TS-2096 xref: FMA:63875 xref: MESH:D003239 is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: BFO:0000050 UBERON:0002384 ! part of connective tissue relationship: BFO:0000050 UBERON:0002384 ! part of connective tissue creation_date: 2010-09-15T03:01:54Z [Term] id: CL:0002321 name: embryonic cell (metazoa) def: "A cell of the embryo." [FMA:0618947256] xref: CALOHA:TS-0263 xref: FMA:82840 xref: WBbt:0007028 is_a: CL:0000000 ! cell property_value: skos:prefLabel "embryonic cell (metazoa)" xsd:string creation_date: 2010-09-15T03:39:21Z [Term] id: CL:0002333 name: neural crest derived adipocyte def: "An adipocyte derived from a neural crest cell." [GOC:tfm, PMID:17507398] is_a: CL:0000136 ! adipocyte is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: CL:0000136 ! adipocyte intersection_of: RO:0002202 CL:0000333 ! develops from migratory neural crest cell relationship: RO:0002202 CL:0000005 ! develops from fibroblast neural crest derived creation_date: 2010-09-20T02:25:25Z [Term] id: CL:0002350 name: endocardial cell def: "An endothelial cell that lines the intracavitary lumen of the heart, separating the circulating blood from the underlying myocardium. This cell type releases a number of vasoactive substances including prostacyclin, nitrous oxide and endothelin." [GOC:tfm, ISSN:0452-3458] synonym: "endocardial endothelial cell" EXACT [] synonym: "endothelial cell of endocardium" EXACT [FMA:75621] xref: FMA:75621 is_a: CL:0010008 ! cardiac endothelial cell intersection_of: CL:0000115 ! endothelial cell intersection_of: BFO:0000050 UBERON:0002165 ! part of endocardium relationship: BFO:0000050 UBERON:0002165 ! part of endocardium creation_date: 2010-09-21T04:33:05Z [Term] id: CL:0002351 name: progenitor cell of endocrine pancreas def: "A progenitor cell that is able to differentiate into the pancreas alpha, beta and delta endocrine cells. This cell type expresses neurogenin-3 and Isl-1." [GOC:tfm, PMID:20025937, PMID:20217494, PMID:22728667] synonym: "pancreatic endocrine progenitor" EXACT [] synonym: "pancreatic islet progenitor cell" EXACT [] is_a: CL:0011026 ! progenitor cell creation_date: 2010-09-21T04:41:06Z [Term] id: CL:0002352 name: gestational hematopoietic stem cell def: "A hematopoietic stem cell that exists during embryogenesis." [GOC:tfm, ISBN:978-60327-246-6] is_a: CL:0000037 ! hematopoietic stem cell intersection_of: CL:0000037 ! hematopoietic stem cell intersection_of: BFO:0000050 UBERON:0000922 ! part of embryo relationship: BFO:0000050 UBERON:0000922 ! part of embryo creation_date: 2010-09-22T09:05:13Z [Term] id: CL:0002359 name: placental hematopoietic stem cell def: "A hematopoietic stem cell of the placenta. This cell type is first observed E10.5 This cell type may give rise to fetal liver hematopoietic stem cells." [GOC:tfm, ISBN:978-1-60327-346-6] is_a: CL:0002352 ! gestational hematopoietic stem cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000037 ! hematopoietic stem cell intersection_of: BFO:0000050 UBERON:0001987 ! part of placenta relationship: BFO:0000050 UBERON:0001987 ! part of placenta creation_date: 2010-09-22T10:30:02Z [Term] id: CL:0002363 name: keratocyte def: "A keratocyte is a specialized fibroblast residing in the cornea stroma that has a flattened, dendritic morphology; located between the lamellae with a large flattened nucleus, and lengthy processes which communicate with neighboring cells. This corneal layer, representing about 85-90% of corneal thickness, is built up from highly regular collagenous lamellae and extracellular matrix components. Keratocytes play the major role in keeping it transparent, healing its wounds, and synthesizing its components. This cell type secretes collagen I, V, VI, and keratan sulfate." [GOC:tfm, ISBN:9780702029585] synonym: "corneal fibroblast" EXACT [] synonym: "corneal keratocyte" EXACT [] is_a: CL:0000005 ! fibroblast neural crest derived intersection_of: CL:0000057 ! fibroblast intersection_of: BFO:0000050 UBERON:0001777 ! part of substantia propria of cornea relationship: BFO:0000050 UBERON:0001777 ! part of substantia propria of cornea creation_date: 2010-09-22T01:57:40Z [Term] id: CL:0002368 name: respiratory epithelial cell def: "An endo-epithelial cell of the respiratory tract." [GOC:tfm] synonym: "airway epithelial cell" EXACT [] xref: BTO:0004533 is_a: CL:0002076 ! endo-epithelial cell intersection_of: CL:0002076 ! endo-epithelial cell intersection_of: BFO:0000050 UBERON:0000065 ! part of respiratory tract relationship: BFO:0000050 UBERON:0000065 ! part of respiratory tract creation_date: 2010-09-23T04:38:49Z [Term] id: CL:0002372 name: myotube def: "A transversely striated, synctial muscle cell, formed by the fusion of myoblasts." [GOC:dos, GOC:tfm, ISBN:0323052908, PMID:22274696] synonym: "myotubule" EXACT [] synonym: "single cell sarcomere" EXACT [] xref: FBbt:00005812 is_a: CL:0000228 ! multinucleate cell is_a: CL:0000737 ! striated muscle cell intersection_of: CL:0000187 ! muscle cell intersection_of: BFO:0000051 GO:0030017 ! has part sarcomere intersection_of: RO:0000053 PATO:0001908 ! has characteristic multinucleate intersection_of: RO:0000053 PATO:0002478 ! has characteristic transversely striated relationship: RO:0000053 PATO:0002478 ! has characteristic transversely striated creation_date: 2010-09-24T01:13:01Z [Term] id: CL:0002421 name: nucleated reticulocyte def: "A reticulocyte that retains the nucleus and other organelles. Found in birds, fish, amphibians and reptiles." [GOC:tfm, PMID:18182572, PMID:9011180, PMID:9046052] is_a: CL:0000558 ! reticulocyte is_a: CL:0002242 ! nucleate cell intersection_of: CL:0000558 ! reticulocyte intersection_of: RO:0000053 PATO:0002505 ! has characteristic nucleated creation_date: 2010-10-15T09:24:05Z [Term] id: CL:0002422 name: enucleated reticulocyte def: "A reticulocyte lacking a nucleus and showing a basophilic reticulum under vital staining due to the presence of ribosomes." [GOC:tfm, ISBN:0-12203-052-4, ISBN:0721601464] xref: CALOHA:TS-0864 xref: FMA:66785 is_a: CL:0000225 ! anucleate cell is_a: CL:0000558 ! reticulocyte intersection_of: CL:0000558 ! reticulocyte intersection_of: BFO:0000051 GO:0005840 ! has part ribosome intersection_of: RO:0000053 PATO:0001405 ! has characteristic anucleate relationship: BFO:0000051 GO:0005840 ! has part ribosome creation_date: 2010-10-15T09:24:08Z [Term] id: CL:0002494 name: cardiocyte def: "A cell located in the heart, including both muscle and non muscle cells." [GOC:tfm] synonym: "heart cell" EXACT [] xref: BTO:0001539 xref: CALOHA:TS-0115 xref: FMA:83808 xref: FMA:84791 is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: BFO:0000050 UBERON:0007100 ! part of primary circulatory organ relationship: BFO:0000050 UBERON:0007100 ! part of primary circulatory organ creation_date: 2010-12-07T09:37:22Z [Term] id: CL:0002503 name: adventitial cell def: "A cell of the adventitial layer of ductal structures such as the uterer, defent duct, biliary duct, etc" [GOC:tfm] xref: BTO:0002441 xref: FMA:84639 is_a: CL:0000630 ! supporting cell is_a: CL:0002320 ! connective tissue cell intersection_of: CL:0002320 ! connective tissue cell intersection_of: BFO:0000050 UBERON:0005742 ! part of adventitia relationship: BFO:0000050 UBERON:0005742 ! part of adventitia creation_date: 2010-12-07T04:03:56Z [Term] id: CL:0002504 name: enteric smooth muscle cell def: "A smooth muscle cell of the intestine." [GOC:tfm] synonym: "intestinal smooth muscle cell" EXACT [] is_a: CL:0000192 ! smooth muscle cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: BFO:0000050 UBERON:0000160 ! part of intestine relationship: BFO:0000050 UBERON:0000160 ! part of intestine creation_date: 2011-01-17T03:39:38Z [Term] id: CL:0002518 name: kidney epithelial cell def: "An epithelial cell of the kidney." [GOC:tfm, KUPO:SJ] xref: KUPO:0001019 is_a: CL:0000066 ! epithelial cell is_a: CL:1000497 ! kidney cell intersection_of: CL:0000066 ! epithelial cell intersection_of: BFO:0000050 UBERON:0002113 ! part of kidney creation_date: 2011-02-08T10:46:34Z [Term] id: CL:0002521 name: subcutaneous adipocyte def: "An adipocyte that is part of subcutaneous adipose tissue." [GOC:tfm] synonym: "subcutaneous fat cell" EXACT [] is_a: CL:0000136 ! adipocyte is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000136 ! adipocyte intersection_of: BFO:0000050 UBERON:0002190 ! part of subcutaneous adipose tissue relationship: BFO:0000050 UBERON:0002190 ! part of subcutaneous adipose tissue creation_date: 2011-02-21T02:51:22Z [Term] id: CL:0002538 name: intrahepatic cholangiocyte def: "An epithelial cell of the intrahepatic portion of the bile duct. These cells are flattened or cuboidal in shape, and have a small nuclear-to-cytoplasmic ratio relative to large/extrahepatic cholangiocytes." [GOC:tfm, PMID:23720296] synonym: "small bile duct cholangiocyte" EXACT [PMID:23720296] is_a: CL:1000488 ! cholangiocyte intersection_of: CL:1000488 ! cholangiocyte intersection_of: BFO:0000050 UBERON:0004823 ! part of intrahepatic bile duct epithelium relationship: BFO:0000050 UBERON:0004823 ! part of intrahepatic bile duct epithelium creation_date: 2011-02-28T01:20:20Z [Term] id: CL:0002539 name: aortic smooth muscle cell def: "A smooth muscle cell of the aorta." [GOC:tfm] xref: BTO:0004577 is_a: CL:0019018 ! blood vessel smooth muscle cell intersection_of: CL:0000359 ! vascular associated smooth muscle cell intersection_of: BFO:0000050 UBERON:0004178 ! part of aorta smooth muscle tissue relationship: BFO:0000050 UBERON:0004178 ! part of aorta smooth muscle tissue creation_date: 2011-02-28T01:42:12Z [Term] id: CL:0002540 name: mesenchymal stem cell of the bone marrow def: "A mesenchymal stem cell that is part of the bone marrow." [GOC:tfm] is_a: CL:0000134 ! mesenchymal stem cell is_a: CL:0002092 ! bone marrow cell intersection_of: CL:0000134 ! mesenchymal stem cell intersection_of: BFO:0000050 UBERON:0002371 ! part of bone marrow creation_date: 2011-02-28T01:47:47Z [Term] id: CL:0002541 name: chorionic membrane mesenchymal stem cell def: "A mesenchymal stem cell of the chorionic membrane." [GOC:tfm] is_a: CL:0000134 ! mesenchymal stem cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000134 ! mesenchymal stem cell intersection_of: BFO:0000050 UBERON:0003124 ! part of chorion membrane relationship: BFO:0000050 UBERON:0003124 ! part of chorion membrane creation_date: 2011-02-28T03:04:35Z [Term] id: CL:0002543 name: vein endothelial cell def: "An endothelial cell that is part of the vein." [GOC:tfm] synonym: "endothelial cell of vein" EXACT [] synonym: "venous endothelial cell" EXACT [] xref: FMA:62104 xref: KUPO:0001099 is_a: CL:0000071 ! blood vessel endothelial cell intersection_of: CL:0000071 ! blood vessel endothelial cell intersection_of: BFO:0000050 UBERON:0001638 ! part of vein relationship: BFO:0000050 UBERON:0001638 ! part of vein creation_date: 2011-02-28T03:48:11Z [Term] id: CL:0002546 name: embryonic blood vessel endothelial progenitor cell def: "An endothelial progenitor cell that participates in angiogenesis during development." [GOC:tfm] is_a: CL:0000222 ! mesodermal cell creation_date: 2011-02-28T04:20:39Z [Term] id: CL:0002547 name: fibroblast of the aortic adventitia def: "A fibroblast of the aortic adventitia." [GOC:tfm] is_a: CL:1000306 ! fibroblast of tunica adventitia of artery intersection_of: CL:1000306 ! fibroblast of tunica adventitia of artery intersection_of: BFO:0000050 UBERON:0004664 ! part of aorta tunica adventitia relationship: BFO:0000050 UBERON:0004664 ! part of aorta tunica adventitia creation_date: 2011-02-28T04:43:41Z [Term] id: CL:0002548 name: fibroblast of cardiac tissue def: "A fibroblast that is part of the heart." [GOC:tfm] synonym: "cardiac fibroblast" EXACT [] is_a: CL:0000057 ! fibroblast is_a: CL:0002494 ! cardiocyte is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000057 ! fibroblast intersection_of: BFO:0000050 UBERON:0000948 ! part of heart relationship: BFO:0000050 UBERON:0000948 ! part of heart creation_date: 2011-02-28T04:57:44Z [Term] id: CL:0002551 name: fibroblast of dermis is_a: CL:0002620 ! skin fibroblast intersection_of: CL:0002620 ! skin fibroblast intersection_of: BFO:0000050 UBERON:0002067 ! part of dermis relationship: BFO:0000050 UBERON:0002067 ! part of dermis creation_date: 2011-02-28T05:05:33Z [Term] id: CL:0002553 name: fibroblast of lung def: "A fibroblast that is part of lung." [GOC:tfm] xref: BTO:0000764 xref: CALOHA:TS-0575 is_a: CL:0000057 ! fibroblast is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: CL:0000057 ! fibroblast intersection_of: BFO:0000050 UBERON:0002048 ! part of lung relationship: BFO:0000050 UBERON:0002048 ! part of lung creation_date: 2011-02-28T05:11:03Z [Term] id: CL:0002557 name: fibroblast of pulmonary artery def: "A fibroblast of pulmonary artery." [GOC:tfm] is_a: CL:0000057 ! fibroblast is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000057 ! fibroblast intersection_of: BFO:0000050 UBERON:0002012 ! part of pulmonary artery relationship: BFO:0000050 UBERON:0002012 ! part of pulmonary artery creation_date: 2011-02-28T05:22:27Z [Term] id: CL:0002563 name: intestinal epithelial cell def: "An epithelial cell of the intestine." [GOC:tfm] is_a: CL:0002251 ! epithelial cell of alimentary canal intersection_of: CL:0000066 ! epithelial cell intersection_of: BFO:0000050 UBERON:0000160 ! part of intestine relationship: BFO:0000050 UBERON:0001277 ! part of intestinal epithelium creation_date: 2011-03-01T05:18:31Z [Term] id: CL:0002569 name: mesenchymal stem cell of umbilical cord def: "A mesenchymal stem cell of the umbilical cord." [GOC:tfm] is_a: CL:0000134 ! mesenchymal stem cell is_a: CL:0000349 ! extraembryonic cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000134 ! mesenchymal stem cell intersection_of: BFO:0000050 UBERON:0003422 ! part of mesenchyme of umbilical cord relationship: BFO:0000050 UBERON:0003422 ! part of mesenchyme of umbilical cord creation_date: 2011-03-01T09:55:12Z [Term] id: CL:0002570 name: mesenchymal stem cell of adipose tissue def: "A mesenchymal stem cell of adipose tissue." [GOC:tfm] synonym: "mesenchymal stem cell of adipose" EXACT [] is_a: CL:0000134 ! mesenchymal stem cell intersection_of: CL:0000134 ! mesenchymal stem cell intersection_of: BFO:0000050 UBERON:0001013 ! part of adipose tissue relationship: BFO:0000050 UBERON:0001013 ! part of adipose tissue creation_date: 2011-03-01T09:57:17Z [Term] id: CL:0002571 name: hepatic mesenchymal stem cell def: "A mesenchymal stem cell of liver." [GOC:tfm] is_a: CL:0000134 ! mesenchymal stem cell is_a: CL:0002195 ! hepatic stem cell intersection_of: CL:0000134 ! mesenchymal stem cell intersection_of: BFO:0000050 UBERON:0002107 ! part of liver creation_date: 2011-03-01T09:58:51Z [Term] id: CL:0002572 name: vertebral mesenchymal stem cell def: "A mesenchymal stem cell of the vertebrae." [GOC:tfm] is_a: CL:0000134 ! mesenchymal stem cell is_a: CL:0001035 ! bone cell intersection_of: CL:0000134 ! mesenchymal stem cell intersection_of: BFO:0000050 UBERON:0002412 ! part of vertebra relationship: BFO:0000050 UBERON:0002412 ! part of vertebra creation_date: 2011-03-01T10:40:27Z [Term] id: CL:0002574 name: stromal cell of pancreas def: "A stromal cell of the pancreas." [GOC:tfm] is_a: CL:0000499 ! stromal cell intersection_of: CL:0000499 ! stromal cell intersection_of: BFO:0000050 UBERON:0001264 ! part of pancreas relationship: BFO:0000050 UBERON:0001264 ! part of pancreas creation_date: 2011-03-02T02:40:41Z [Term] id: CL:0002577 name: placental epithelial cell def: "An epithelial cell of the placenta." [GOC:tfm] is_a: CL:0000066 ! epithelial cell is_a: CL:0000349 ! extraembryonic cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000066 ! epithelial cell intersection_of: BFO:0000050 UBERON:0001987 ! part of placenta relationship: BFO:0000050 UBERON:0001987 ! part of placenta creation_date: 2011-03-02T03:21:30Z [Term] id: CL:0002584 name: renal cortical epithelial cell def: "An epithelial cell of the kidney cortex." [GOC:tfm] xref: KUPO:0001016 is_a: CL:0002518 ! kidney epithelial cell is_a: CL:0002681 ! kidney cortical cell intersection_of: CL:0002518 ! kidney epithelial cell intersection_of: BFO:0000050 UBERON:0001225 ! part of cortex of kidney [Term] id: CL:0002585 name: retinal blood vessel endothelial cell def: "A blood vessel endothelial cell that is part of the retina." [GOC:tfm] is_a: CL:0000071 ! blood vessel endothelial cell is_a: CL:0009004 ! retinal cell is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:0000071 ! blood vessel endothelial cell intersection_of: BFO:0000050 UBERON:0000966 ! part of retina relationship: BFO:0000050 UBERON:0000966 ! part of retina creation_date: 2011-03-06T03:28:27Z [Term] id: CL:0002589 name: smooth muscle cell of the brachiocephalic vasculature def: "A smooth muscle cell of the bachiocephalic vasculature." [GOC:tfm] is_a: CL:0019018 ! blood vessel smooth muscle cell intersection_of: CL:0000359 ! vascular associated smooth muscle cell intersection_of: BFO:0000050 UBERON:0001529 ! part of brachiocephalic artery relationship: BFO:0000050 UBERON:0001529 ! part of brachiocephalic artery creation_date: 2011-03-06T05:00:58Z [Term] id: CL:0002590 name: smooth muscle cell of the brain vasculature def: "A vascular associated smooth muscle cell of the brain vasculature." [GOC:tfm] is_a: CL:0000359 ! vascular associated smooth muscle cell is_a: CL:0002319 ! neural cell is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:0000359 ! vascular associated smooth muscle cell intersection_of: BFO:0000050 UBERON:0000955 ! part of brain relationship: BFO:0000050 UBERON:0000955 ! part of brain creation_date: 2011-03-06T05:01:20Z [Term] id: CL:0002591 name: smooth muscle cell of the pulmonary artery def: "A smooth muscle of the pulmonary artery." [GOC:tfm] xref: BTO:0003336 is_a: CL:0019018 ! blood vessel smooth muscle cell intersection_of: CL:0000359 ! vascular associated smooth muscle cell intersection_of: BFO:0000050 UBERON:0002012 ! part of pulmonary artery relationship: BFO:0000050 UBERON:0002012 ! part of pulmonary artery creation_date: 2011-03-06T05:01:28Z [Term] id: CL:0002594 name: smooth muscle cell of the umbilical artery def: "A smooth muscle cell of the umbilical artery." [GOC:tfm] is_a: CL:0019018 ! blood vessel smooth muscle cell intersection_of: CL:0000359 ! vascular associated smooth muscle cell intersection_of: BFO:0000050 UBERON:0001310 ! part of umbilical artery relationship: BFO:0000050 UBERON:0001310 ! part of umbilical artery creation_date: 2011-03-06T05:01:48Z [Term] id: CL:0002595 name: smooth muscle cell of the subclavian artery def: "A smooth muscle cell of the subclavian artery." [GOC:tfm] is_a: CL:0019018 ! blood vessel smooth muscle cell intersection_of: CL:0000359 ! vascular associated smooth muscle cell intersection_of: BFO:0000050 UBERON:0001533 ! part of subclavian artery relationship: BFO:0000050 UBERON:0001533 ! part of subclavian artery creation_date: 2011-03-06T05:01:52Z [Term] id: CL:0002596 name: smooth muscle cell of the carotid artery def: "Smooth muscle cell of the carotid artery." [GOC:tfm] is_a: CL:0019018 ! blood vessel smooth muscle cell intersection_of: CL:0000359 ! vascular associated smooth muscle cell intersection_of: BFO:0000050 UBERON:0005396 ! part of carotid artery segment relationship: BFO:0000050 UBERON:0005396 ! part of carotid artery segment creation_date: 2011-03-06T05:01:56Z [Term] id: CL:0002597 name: smooth muscle cell of bladder def: "A smooth muscle cell of the bladder." [GC:tfm] xref: KUPO:0001122 is_a: CL:0000192 ! smooth muscle cell is_a: CL:1001319 ! bladder cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: BFO:0000050 UBERON:0001255 ! part of urinary bladder creation_date: 2011-03-06T05:43:24Z [Term] id: CL:0002599 name: smooth muscle cell of the esophagus def: "A smooth muscle cell of the esophagus." [GOC:tfm] is_a: CL:0000192 ! smooth muscle cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: BFO:0000050 UBERON:0001043 ! part of esophagus relationship: BFO:0000050 UBERON:0001043 ! part of esophagus creation_date: 2011-03-06T05:48:17Z [Term] id: CL:0002601 name: uterine smooth muscle cell def: "A smooth muscle cell of the uterus." [GOC:tfm] is_a: CL:0000192 ! smooth muscle cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: BFO:0000050 UBERON:0000995 ! part of uterus relationship: BFO:0000050 UBERON:0000995 ! part of uterus creation_date: 2011-03-06T05:53:28Z [Term] id: CL:0002610 name: raphe nuclei neuron def: "A neuron of the raphe nuclei." [GOC:tfm] is_a: CL:0000117 ! CNS neuron (sensu Vertebrata) is_a: CL:2000029 ! central nervous system neuron intersection_of: CL:0000117 ! CNS neuron (sensu Vertebrata) intersection_of: RO:0002100 UBERON:0004684 ! has soma location raphe nuclei relationship: RO:0002100 UBERON:0004684 ! has soma location raphe nuclei creation_date: 2011-03-06T07:42:06Z [Term] id: CL:0002612 name: neuron of the ventral spinal cord def: "A neuron of the ventral spinal cord." [GOC:tfm] is_a: CL:0000117 ! CNS neuron (sensu Vertebrata) is_a: CL:2000029 ! central nervous system neuron intersection_of: CL:0000117 ! CNS neuron (sensu Vertebrata) intersection_of: RO:0002100 UBERON:0002257 ! has soma location ventral horn of spinal cord relationship: RO:0002100 UBERON:0002257 ! has soma location ventral horn of spinal cord creation_date: 2011-03-06T07:46:03Z [Term] id: CL:0002620 name: skin fibroblast def: "A fibroblast of skin." [GOC:tfm] xref: BTO:0001255 xref: CALOHA:TS-0935 is_a: CL:0000057 ! fibroblast is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:0000057 ! fibroblast intersection_of: BFO:0000050 UBERON:0002097 ! part of skin of body relationship: BFO:0000050 UBERON:0002097 ! part of skin of body creation_date: 2011-03-14T12:31:49Z [Term] id: CL:0002625 name: seminiferous tubule epithelial cell def: "A cell of the seminiferous tubule epithelium." [GOC:tfm] is_a: CL:0000068 ! duct epithelial cell is_a: CL:0000077 ! mesothelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: BFO:0000050 UBERON:0001343 ! part of seminiferous tubule of testis relationship: BFO:0000050 UBERON:0004813 ! part of seminiferous tubule epithelium creation_date: 2011-03-15T11:59:23Z [Term] id: CL:0002632 name: epithelial cell of lower respiratory tract is_a: CL:0002368 ! respiratory epithelial cell intersection_of: CL:0002368 ! respiratory epithelial cell intersection_of: BFO:0000050 UBERON:0001558 ! part of lower respiratory tract relationship: BFO:0000050 UBERON:0001558 ! part of lower respiratory tract creation_date: 2011-06-21T12:29:31Z [Term] id: CL:0002656 name: glandular cell of endometrium def: "A glandular epithelial cell of the endometrium." [GOC:tfm] xref: FMA:86489 is_a: CL:1001591 ! oviduct glandular cell intersection_of: CL:0000150 ! glandular epithelial cell intersection_of: BFO:0000050 UBERON:0001295 ! part of endometrium relationship: BFO:0000050 UBERON:0001295 ! part of endometrium creation_date: 2011-07-08T03:54:08Z [Term] id: CL:0002657 name: glandular cell of esophagus def: "A glandular epithelial cell of the esophagus." [GOC:tfm] xref: FMA:86548 is_a: CL:0000150 ! glandular epithelial cell is_a: CL:0002252 ! epithelial cell of esophagus intersection_of: CL:0000150 ! glandular epithelial cell intersection_of: BFO:0000050 UBERON:0001043 ! part of esophagus creation_date: 2011-07-08T03:55:57Z [Term] id: CL:0002658 name: glandular cell of the large intestine def: "A glandular epithelial cell of the large intestine." [GOC:tfm] xref: FMA:87194 is_a: CL:0000150 ! glandular epithelial cell is_a: CL:0002253 ! epithelial cell of large intestine intersection_of: CL:0000150 ! glandular epithelial cell intersection_of: BFO:0000050 UBERON:0000059 ! part of large intestine creation_date: 2011-07-08T04:03:01Z [Term] id: CL:0002659 name: glandular cell of stomach def: "A glandular epithelial cell that is part of the stomach." [GOC:tfm] xref: CALOHA:TS-1284 xref: FMA:86554 is_a: CL:0000150 ! glandular epithelial cell is_a: CL:0002178 ! epithelial cell of stomach intersection_of: CL:0000150 ! glandular epithelial cell intersection_of: BFO:0000050 UBERON:0000945 ! part of stomach creation_date: 2011-07-11T01:20:35Z [Term] id: CL:0002663 name: myocardial endocrine cell of atrium def: "A myocardial endocrine cell that is part of the atrium." [GOC:tfm] xref: FMA:83389 is_a: CL:0002074 ! myocardial endocrine cell intersection_of: CL:0002074 ! myocardial endocrine cell intersection_of: BFO:0000050 UBERON:0002081 ! part of cardiac atrium relationship: BFO:0000050 UBERON:0002081 ! part of cardiac atrium creation_date: 2011-07-11T02:45:39Z [Term] id: CL:0002664 name: cardioblast def: "A stem cell that can give rise to multiple cell types (i.e. smooth muscle, endothelial) in the developing heart." [GOC:tfm, PMID:19745164] synonym: "cardiovascular progenitor cell" EXACT [PMID:17519333, PMID:19745164] is_a: CL:0000048 ! multi fate stem cell creation_date: 2011-07-11T03:15:38Z [Term] id: CL:0002672 name: retinal progenitor cell def: "A multi-fate stem cell that can give rise to different retinal cell types including rod and cone cells." [GOC:tfm, PMID:20959166, PMID:21148186] is_a: CL:0000048 ! multi fate stem cell is_a: UBERON:0004121 ! ectoderm-derived structure relationship: RO:0002202 CL:0000133 ! develops from neurectodermal cell creation_date: 2011-08-16T02:38:01Z [Term] id: CL:0002676 name: neural crest derived neuroblast def: "A neuroblast derived from a neural crest cell." [GOC:tfm, PMID:17407019] is_a: CL:0000031 ! neuroblast (sensu Vertebrata) is_a: CL:0011026 ! progenitor cell is_a: UBERON:0010313 ! neural crest-derived structure relationship: RO:0002202 CL:0000333 ! develops from migratory neural crest cell creation_date: 2011-08-22T09:24:15Z [Term] id: CL:0002680 name: PP cell of intestine def: "A PP cell found in intestine." [GOC:tfm, PMID:2420136, PMID:728970] is_a: CL:0000696 ! PP cell is_a: CL:1001516 ! intestinal enteroendocrine cell intersection_of: CL:0000696 ! PP cell intersection_of: BFO:0000050 UBERON:0000160 ! part of intestine creation_date: 2011-09-27T11:59:01Z [Term] id: CL:0002681 name: kidney cortical cell def: "A cell that is part of a cortex of kidney." [] is_a: CL:1000497 ! kidney cell intersection_of: CL:1000497 ! kidney cell intersection_of: BFO:0000050 UBERON:0001225 ! part of cortex of kidney relationship: BFO:0000050 UBERON:0001225 ! part of cortex of kidney creation_date: 2011-10-25T03:49:41Z [Term] id: CL:0005000 name: spinal cord interneuron def: "A CNS interneuron located in the spinal cord." [CL:CVS] is_a: CL:0000402 ! CNS interneuron intersection_of: CL:0000099 ! interneuron intersection_of: RO:0002100 UBERON:0002240 ! has soma location spinal cord relationship: RO:0002100 UBERON:0002240 ! has soma location spinal cord [Term] id: CL:0005009 name: renal principal cell def: "A cuboidal epithelial cell of the kidney which regulates sodium and potassium balance. The activity of sodium and potassium channels on the apical membrane of the cell is regulated by aldosterone and vasopressin. In mammals this cell type is located in the renal collecting duct system." [CL:CVS] is_a: CL:0000075 ! columnar/cuboidal epithelial cell is_a: CL:0002518 ! kidney epithelial cell [Term] id: CL:0005024 name: somatomotor neuron def: "A motor neuron that innervates a skeletal muscle. These motor neurons are all excitatory and cholinergic." [ZFIN:CVS] synonym: "somatic motor neuron" EXACT [] is_a: CL:0000100 ! motor neuron is_a: CL:0000108 ! cholinergic neuron intersection_of: CL:0000100 ! motor neuron intersection_of: RO:0002120 CL:0008002 ! synapsed to skeletal muscle fiber relationship: BFO:0000050 RO:0002577 ! part of system relationship: RO:0002120 CL:0008002 ! synapsed to skeletal muscle fiber relationship: RO:0002202 CL:0000031 ! develops from neuroblast (sensu Vertebrata) [Term] id: CL:0005026 name: hepatoblast def: "Multi fate stem cell that gives rise to both hepatocytes and cholangiocytes as descendants. The term often refers to fetal precursors of hepatocytes (differently from 'hepatic stem cell', usually applied to the self-renewing pool of hepatocyte precursors in the adult liver). Hepatoblasts may also be endogenous, as some stem cells found in the liver come from the bone marrow via blood circulation." [GOC:CVS, https://orcid.org/0000-0003-1940-6740, PMID:18356246, PMID:20483998, PMID:26798363] is_a: CL:0000048 ! multi fate stem cell [Term] id: CL:0007001 name: skeletogenic cell def: "Cell that has the potential to form a skeletal cell type (e.g. cells in periosteum, cells in marrow) and produce extracellular matrix (often mineralized) and skeletal tissue (often mineralized)." [GO_REF:0000034] synonym: "scleroblast" EXACT [GO_REF:0000034] is_a: CL:0000000 ! cell creation_date: 2012-06-15T02:51:27Z [Term] id: CL:0007004 name: premigratory neural crest cell def: "Cell that is part of the neural crest region of the neuroepithelium, prior to migration. Note that not all premigratory neural crest cells may become migratory neural crest cells." [UBERONREF:0000002] is_a: CL:0011012 ! neural crest cell is_a: UBERON:0004121 ! ectoderm-derived structure relationship: BFO:0000050 UBERON:0002342 ! part of neural crest relationship: RO:0002202 CL:0000133 ! develops from neurectodermal cell creation_date: 2012-06-27T08:27:35Z [Term] id: CL:0007009 name: prechondroblast def: "Skeletogenic cell that has the potential to develop into a chondroblast; and arises from neural crest, meseosdermal and notochordal and connective tissue cells." [GO_REF:0000034] is_a: CL:0000055 ! non-terminally differentiated cell creation_date: 2012-06-27T10:44:01Z [Term] id: CL:0008000 name: non-striated muscle cell def: "Any muscle cell in which the fibers are not organised into sarcomeres." [GOC:DOS] is_a: CL:0000187 ! muscle cell [Term] id: CL:0008001 name: hematopoietic precursor cell def: "Any hematopoietic cell that is a precursor of some other hematopoietic cell type." [GOC:dos] is_a: CL:0000988 ! hematopoietic cell [Term] id: CL:0008002 name: skeletal muscle fiber def: "A transversely striated, synctial cell of skeletal muscle. It is formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." [GOC:tfm, ISBN:0323052908] xref: MESH:D018485 is_a: CL:0000188 ! cell of skeletal muscle is_a: CL:0002372 ! myotube intersection_of: CL:0000187 ! muscle cell intersection_of: BFO:0000050 UBERON:0001134 ! part of skeletal muscle tissue intersection_of: BFO:0000051 GO:0030017 ! has part sarcomere intersection_of: RO:0000053 PATO:0001908 ! has characteristic multinucleate intersection_of: RO:0000053 PATO:0002478 ! has characteristic transversely striated relationship: RO:0002202 CL:0000515 ! develops from skeletal muscle myoblast [Term] id: CL:0008007 name: visceral muscle cell def: "A muscle cell that is part of some visceral muscle." [GOC:dos] xref: FBbt:00005070 is_a: CL:0000187 ! muscle cell intersection_of: CL:0000187 ! muscle cell intersection_of: BFO:0000050 UBERON:8600004 ! part of visceral muscle tissue relationship: BFO:0000050 UBERON:8600004 ! part of visceral muscle tissue [Term] id: CL:0008008 name: striated visceral muscle cell def: "A visceral muscle cell that is striated. Examples include the visceral muscle cells of arhtropods." [GOC:dos] is_a: CL:0000737 ! striated muscle cell is_a: CL:0008007 ! visceral muscle cell intersection_of: CL:0008007 ! visceral muscle cell intersection_of: RO:0000053 PATO:0001410 {all_some="true"} ! has characteristic striated [Term] id: CL:0008009 name: transversely striated visceral muscle cell def: "A visceral muscle that is transversely striated. Examples include the visceral muscle cells of arthropods." [GOC:dos] is_a: CL:0008008 ! striated visceral muscle cell intersection_of: CL:0008007 ! visceral muscle cell intersection_of: RO:0000053 PATO:0002478 {all_some="true"} ! has characteristic transversely striated relationship: RO:0000053 PATO:0002478 ! has characteristic transversely striated [Term] id: CL:0008017 name: adult skeletal muscle myoblast def: "A skeletal muscle myoblast that is part of a skeletal mucle. These cells are formed following acivation and division of skeletal muscle satellite cells. They form a transient population that is lost when they fuse to form skeletal muscle fibers." [PMID:23303905] is_a: CL:0000188 ! cell of skeletal muscle is_a: CL:0000515 ! skeletal muscle myoblast intersection_of: CL:0000056 ! myoblast intersection_of: BFO:0000050 UBERON:0001134 ! part of skeletal muscle tissue intersection_of: RO:0002203 CL:0008002 ! develops into skeletal muscle fiber [Term] id: CL:0008019 name: mesenchymal cell def: "A non-polarised cell precursor cell that is part of some mesenchyme, is associated with the cell matrix but is not connected to other cells and is capable of migration." [] synonym: "mesenchyme cell" EXACT [] is_a: CL:0000219 ! motile cell is_a: CL:0000255 ! eukaryotic cell relationship: BFO:0000050 UBERON:0003104 ! part of mesenchyme relationship: RO:0002215 GO:0016477 ! capable of cell migration [Term] id: CL:0008022 name: endocardial cushion cell def: "A mesenchymal cell of the endocardial cushion. These cells develop via an epithelial to mesenchymal transition when endocardial cells break cell-to-cell contacts and migrate into the cardiac jelly. Cells from this population form the heart septa and valves." [PMID:18816864] is_a: CL:0000569 ! cardiac mesenchymal cell is_a: CL:0002494 ! cardiocyte is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000569 ! cardiac mesenchymal cell intersection_of: BFO:0000050 UBERON:0002062 ! part of endocardial cushion relationship: BFO:0000050 UBERON:0002062 ! part of endocardial cushion [Term] id: CL:0008024 name: pancreatic endocrine cell def: "An endocrine cell that is part of the pancreas." [GOC:dos] is_a: CL:0000083 ! epithelial cell of pancreas is_a: CL:0000164 ! enteroendocrine cell intersection_of: CL:0000163 ! endocrine cell intersection_of: BFO:0000050 UBERON:0001264 ! part of pancreas [Term] id: CL:0008025 name: noradrenergic neuron def: "A neuron that release noradrenaline (noriphinephrine) as a neurotransmitter." [GOC:dos] is_a: CL:0000459 ! noradrenergic cell is_a: CL:4033050 ! catecholaminergic neuron intersection_of: CL:0000540 ! neuron intersection_of: RO:0002215 GO:0061533 ! capable of norepinephrine secretion, neurotransmission relationship: RO:0002215 GO:0061533 ! capable of norepinephrine secretion, neurotransmission [Term] id: CL:0008028 name: visual system neuron is_a: CL:0000540 ! neuron intersection_of: CL:0000540 ! neuron intersection_of: RO:0002216 GO:0007601 ! capable of part of visual perception relationship: RO:0002216 GO:0007601 ! capable of part of visual perception creation_date: 2017-07-09T19:12:36Z [Term] id: CL:0008034 name: mural cell def: "Mural cells are pericytes and the vascular smooth muscle cells (vSMCs) of the microcirculation." [Wiki:Mural_cell&oldid=930603194] is_a: CL:4033054 ! perivascular cell creation_date: 2020-02-29T17:33:55Z [Term] id: CL:0008035 name: microcirculation associated smooth muscle cell is_a: CL:0000359 ! vascular associated smooth muscle cell is_a: CL:0008034 ! mural cell intersection_of: CL:0000359 ! vascular associated smooth muscle cell intersection_of: BFO:0000050 UBERON:0010523 ! part of microcirculatory vessel relationship: BFO:0000050 UBERON:0010523 ! part of microcirculatory vessel creation_date: 2020-02-29T17:37:00Z [Term] id: CL:0009000 name: sensory neuron of spinal nerve def: "A sensory neuron of the spinal nerve that senses body position and sends information about how much the muscle is stretched to the spinal cord." [GOC:nv, GOC:pr] synonym: "spinal sensory neuron" EXACT [] is_a: CL:3000004 ! peripheral sensory neuron intersection_of: CL:0000101 ! sensory neuron intersection_of: RO:0002100 UBERON:0001780 ! has soma location spinal nerve relationship: RO:0002100 UBERON:0001780 ! has soma location spinal nerve [Term] id: CL:0009001 name: compound eye retinal cell def: "Any cell in the compound eye, a light sensing organ composed of ommatidia." [] xref: GOC:pr xref: PMID:12021768 is_a: CL:0009004 ! retinal cell [Term] id: CL:0009004 name: retinal cell def: "Any cell in the retina, the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates." [GOC:pr] xref: PMID:10702418 is_a: CL:0002319 ! neural cell intersection_of: CL:0002319 ! neural cell intersection_of: BFO:0000050 UBERON:0005388 ! part of photoreceptor array relationship: BFO:0000050 UBERON:0005388 ! part of photoreceptor array [Term] id: CL:0009006 name: enteroendocrine cell of small intestine def: "An enteroendocrine cell that is located in the small intestine." [http://orcid.org/0000-0003-3440-1876] synonym: "small intestine enteroendocrine cell" EXACT [] is_a: CL:1001516 ! intestinal enteroendocrine cell is_a: CL:1001598 ! small intestine glandular cell intersection_of: CL:0000164 ! enteroendocrine cell intersection_of: BFO:0000050 UBERON:0002108 ! part of small intestine [Term] id: CL:0009018 name: lymphocyte of large intestine lamina propria def: "A lymphocyte that resides in the lamina propria of the large intestine." [https://orcid.org/0000-0003-4183-8865] synonym: "lamina propria lymphocyte of large intestine" EXACT [] is_a: CL:0000542 ! lymphocyte intersection_of: CL:0000542 ! lymphocyte intersection_of: BFO:0000050 UBERON:0011189 ! part of lamina propria of large intestine relationship: BFO:0000050 UBERON:0011189 ! part of lamina propria of large intestine [Term] id: CL:0009019 name: nephrogenic zone cell def: "A kidney cortical cell that is part of the nephrogenic zone." [https://orcid.org/0000-0002-3163-0115, PMID:29449449] synonym: "cortical nephrogenic niche cell" EXACT [] synonym: "cortical nephrogenic zone cell" EXACT [] is_a: CL:0002681 ! kidney cortical cell intersection_of: CL:0002681 ! kidney cortical cell intersection_of: BFO:0000050 UBERON:0009871 ! part of nephrogenic zone relationship: BFO:0000050 UBERON:0009871 ! part of nephrogenic zone [Term] id: CL:0009021 name: stromal cell of lamina propria of large intestine def: "A stromal cell found in the lamina propria of the large intestine." [http://orcid.org/0000-0003-4183-8865] is_a: CL:0000499 ! stromal cell intersection_of: CL:0000499 ! stromal cell intersection_of: BFO:0000050 UBERON:0011189 ! part of lamina propria of large intestine relationship: BFO:0000050 UBERON:0011189 ! part of lamina propria of large intestine [Term] id: CL:0009022 name: stromal cell of lamina propria of small intestine def: "A stromal cell found in the lamina propria of the small intestine." [http://orcid.org/0000-0003-4183-8865] is_a: CL:0000499 ! stromal cell intersection_of: CL:0000499 ! stromal cell intersection_of: BFO:0000050 UBERON:0001238 ! part of lamina propria of small intestine relationship: BFO:0000050 UBERON:0001238 ! part of lamina propria of small intestine [Term] id: CL:0009024 name: mesothelial cell of small intestine def: "A mesothelial cell that is part of the small intestine." [http://orcid.org/0000-0003-4183-8865] is_a: CL:0000077 ! mesothelial cell is_a: CL:0002254 ! epithelial cell of small intestine is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure intersection_of: CL:0000077 ! mesothelial cell intersection_of: BFO:0000050 UBERON:0002108 ! part of small intestine [Term] id: CL:0009025 name: mesothelial cell of colon def: "A mesothelial cell that is part of the colon." [http://orcid.org/0000-0003-3440-1876, http://orcid.org/0000-0003-4183-8865] is_a: CL:0000077 ! mesothelial cell is_a: CL:0011108 ! colon epithelial cell is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure intersection_of: CL:0000077 ! mesothelial cell intersection_of: BFO:0000050 UBERON:0001155 ! part of colon [Term] id: CL:0009040 name: stromal cell of lamina propria of colon def: "A stromal cell found in the lamina propria of the colon." [http://orcid.org/0000-0003-3440-1876] synonym: "stromal cell of colon lamina propria" EXACT [] is_a: CL:0009021 ! stromal cell of lamina propria of large intestine intersection_of: CL:0000499 ! stromal cell intersection_of: BFO:0000050 UBERON:0007177 ! part of lamina propria of mucosa of colon relationship: BFO:0000050 UBERON:0007177 ! part of lamina propria of mucosa of colon [Term] id: CL:0009042 name: enteroendocrine cell of colon def: "An enteroendocrine cell that is located in the colon." [http://orcid.org/0000-0003-3440-1876] synonym: "colon enteroendocrine cell" EXACT [] is_a: CL:1001516 ! intestinal enteroendocrine cell is_a: CL:1001588 ! colon glandular cell intersection_of: CL:0000164 ! enteroendocrine cell intersection_of: BFO:0000050 UBERON:0001155 ! part of colon [Term] id: CL:0009044 name: lymphocyte of small intestine lamina propria def: "A lymphocyte that resides in the lamina propria of the small intestine. Lamina propria leukocytes and intraepithelial lymphocytes are the effector compartments of the gut mucosal immune system. Lymphocytes circulate through gut associated lymphoid tissues until recruitment by intestinal antigens. They are involved in the gut immune response." [https://orcid.org/0000-0003-4183-8865, PMID:26551552] synonym: "gastrointestinal tract (lamina propria) lymphocyte of small intestine" EXACT [] synonym: "lamina propria lymphocyte of small intestine" EXACT [] synonym: "small intestine lamina propria lymphocyte" EXACT [] is_a: CL:0000542 ! lymphocyte intersection_of: CL:0000542 ! lymphocyte intersection_of: BFO:0000050 UBERON:0001238 ! part of lamina propria of small intestine relationship: BFO:0000050 UBERON:0001238 ! part of lamina propria of small intestine [Term] id: CL:0009051 name: T cell of anorectum def: "A T cell that is located in the anorectum." [http://orcid.org/0000-0003-3440-1876] is_a: CL:0000084 ! T cell intersection_of: CL:0000084 ! T cell intersection_of: BFO:0000050 UBERON:8410050 ! part of anorectum relationship: BFO:0000050 UBERON:8410050 ! part of anorectum [Term] id: CL:0009052 name: smooth muscle cell of anorectum def: "A smooth muscle cell that is located in the anorectum." [http://orcid.org/0000-0003-3440-1876] synonym: "anorectum smooth muscle cell" EXACT [] is_a: CL:1000279 ! smooth muscle cell of large intestine intersection_of: CL:0000192 ! smooth muscle cell intersection_of: BFO:0000050 UBERON:8410050 ! part of anorectum relationship: BFO:0000050 UBERON:8410050 ! part of anorectum [Term] id: CL:0009053 name: stromal cell of anorectum lamina propria def: "A stromal cell found in the lamina propria of the anorectum." [http://orcid.org/0000-0003-3440-1876] is_a: CL:0009021 ! stromal cell of lamina propria of large intestine intersection_of: CL:0000499 ! stromal cell intersection_of: BFO:0000050 UBERON:0011189 ! part of lamina propria of large intestine intersection_of: BFO:0000050 UBERON:8410050 ! part of anorectum relationship: BFO:0000050 UBERON:8410050 ! part of anorectum [Term] id: CL:0009063 name: enteroendocrine cell of anorectum def: "An enteroendocrine cell that is located in the anorectum." [http://orcid.org/0000-0003-3440-1876] synonym: "anorectum enteroendocrine cell" EXACT [] is_a: CL:0002658 ! glandular cell of the large intestine is_a: CL:1001516 ! intestinal enteroendocrine cell intersection_of: CL:0000164 ! enteroendocrine cell intersection_of: BFO:0000050 UBERON:8410050 ! part of anorectum relationship: BFO:0000050 UBERON:8410050 ! part of anorectum [Term] id: CL:0009084 name: epithelial cell of endometrial gland def: "An epithelial cell that is part of an endometrial gland." [https://orcid.org/0000-0003-3440-1876, https://orcid.org/0000-0003-4183-8865] synonym: "endometrial glandular epithelial cell" EXACT [] xref: EFO:0010710 is_a: CL:0000066 ! epithelial cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000066 ! epithelial cell intersection_of: BFO:0000050 UBERON:0002451 ! part of endometrial gland relationship: BFO:0000050 UBERON:0002451 ! part of endometrial gland [Term] id: CL:0009092 name: endothelial cell of placenta def: "An endothelial cell that is part of a placenta." [https://orcid.org/0000-0003-3440-1876, https://orcid.org/0000-0003-4183-8865] synonym: "placental endothelial cell" EXACT [] xref: EFO:0010708 is_a: CL:0000115 ! endothelial cell is_a: CL:0002577 ! placental epithelial cell intersection_of: CL:0000115 ! endothelial cell intersection_of: BFO:0000050 UBERON:0001987 ! part of placenta [Term] id: CL:0009093 name: smooth muscle cell of placenta def: "A smooth muscle cell that is part of a placenta." [https://orcid.org/0000-0003-3440-1876, https://orcid.org/0000-0003-4183-8865] synonym: "placental smooth muscle cell" EXACT [] xref: EFO:0010709 is_a: CL:0000192 ! smooth muscle cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: BFO:0000050 UBERON:0001987 ! part of placenta relationship: BFO:0000050 UBERON:0001987 ! part of placenta [Term] id: CL:0009094 name: endothelial cell of hepatic portal vein def: "An endothelial cell that is part of a hepatic portal vein." [https://orcid.org/0000-0003-3440-1876, https://orcid.org/0000-0003-4183-8865, PMID:30348985] xref: EFO:0010704 is_a: CL:0000115 ! endothelial cell intersection_of: CL:0000115 ! endothelial cell intersection_of: BFO:0000050 UBERON:0001639 ! part of hepatic portal vein relationship: BFO:0000050 UBERON:0001639 ! part of hepatic portal vein [Term] id: CL:0009095 name: endothelial cell of uterus def: "An endothelial cell that is part of a uterus." [https://orcid.org/0000-0003-3440-1876, https://orcid.org/0000-0003-4183-8865] synonym: "uterine endothelial cell" EXACT [] xref: EFO:0010711 is_a: CL:0000115 ! endothelial cell intersection_of: CL:0000115 ! endothelial cell intersection_of: BFO:0000050 UBERON:0000995 ! part of uterus relationship: BFO:0000050 UBERON:0000995 ! part of uterus [Term] id: CL:0009097 name: embryonic skeletal muscle fiber def: "A skeletal muscle fiber found in an embryo. In mammalian embryos, skeletal muscle expresses myosin heavy chain-embryonic (MyHC-emb, encoded by the MYH3 gene), which regulates skeletal muscle development." [http://orcid.org/0000-0003-2034-601X, PMID:32094117, PMID:7196501] is_a: CL:0008002 ! skeletal muscle fiber intersection_of: CL:0008002 ! skeletal muscle fiber intersection_of: RO:0002491 UBERON:0000068 ! existence starts and ends during embryo stage relationship: RO:0002491 UBERON:0000068 ! existence starts and ends during embryo stage [Term] id: CL:0009100 name: hepatic portal fibroblast def: "A fibroblast located in the portal triad. Hepatic portal fibroblast are a non-parenchymal cell population located adjacent to bile duct epithelia in liver and are distinct from stellate cells. They differentiate into fibrogenic myofibroblasts during chronic injury states producing high levels of collagen." [https://orcid.org/0000-0001-7655-4833, PMID:20209607, PMID:24814904] is_a: CL:0000057 ! fibroblast is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: CL:0000057 ! fibroblast intersection_of: BFO:0000050 UBERON:0001279 ! part of portal triad relationship: BFO:0000050 UBERON:0001279 ! part of portal triad [Term] id: CL:0010001 name: stromal cell of bone marrow def: "A stromal cell that is part_of a bone marrow." [] synonym: "bone marrow stromal cell" EXACT [] is_a: CL:0000499 ! stromal cell is_a: CL:0002092 ! bone marrow cell intersection_of: CL:0000499 ! stromal cell intersection_of: BFO:0000050 UBERON:0002371 ! part of bone marrow [Term] id: CL:0010002 name: epithelial cell of umbilical artery def: "An epithelial cell that is part_of a umbilical artery." [] synonym: "umbilical artery epithelial cell" EXACT [] is_a: CL:0000066 ! epithelial cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000066 ! epithelial cell intersection_of: BFO:0000050 UBERON:0001310 ! part of umbilical artery relationship: BFO:0000050 UBERON:0001310 ! part of umbilical artery [Term] id: CL:0010004 name: mononuclear cell of bone marrow def: "A mononuclear cell that is part_of a bone marrow." [] synonym: "bone marrow mononuclear cell" EXACT [] is_a: CL:0000842 ! mononuclear cell is_a: CL:1001610 ! bone marrow hematopoietic cell intersection_of: CL:0000842 ! mononuclear cell intersection_of: BFO:0000050 UBERON:0002371 ! part of bone marrow [Term] id: CL:0010006 name: cardiac blood vessel endothelial cell is_a: CL:0000071 ! blood vessel endothelial cell is_a: CL:0010008 ! cardiac endothelial cell intersection_of: CL:0000071 ! blood vessel endothelial cell intersection_of: BFO:0000050 UBERON:0000948 ! part of heart [Term] id: CL:0010007 name: His-Purkinje system cell is_a: CL:0002494 ! cardiocyte is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000000 ! cell intersection_of: BFO:0000050 UBERON:0004146 ! part of His-Purkinje system relationship: BFO:0000050 UBERON:0004146 ! part of His-Purkinje system [Term] id: CL:0010008 name: cardiac endothelial cell is_a: CL:0000115 ! endothelial cell is_a: CL:0002494 ! cardiocyte intersection_of: CL:0000115 ! endothelial cell intersection_of: BFO:0000050 UBERON:0000948 ! part of heart relationship: BFO:0000050 UBERON:0000948 ! part of heart [Term] id: CL:0010009 name: camera-type eye photoreceptor cell synonym: "camera type eye photoreceptor cell" EXACT [] is_a: CL:0000287 ! eye photoreceptor cell is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:0000210 ! photoreceptor cell intersection_of: BFO:0000050 UBERON:0000019 ! part of camera-type eye relationship: BFO:0000050 UBERON:0000019 ! part of camera-type eye relationship: RO:0002202 CL:0000031 ! develops from neuroblast (sensu Vertebrata) [Term] id: CL:0010017 name: zygote def: "A zygote in a plant or an animal." [] xref: MESH:D015053 is_a: CL:0000000 ! cell [Term] id: CL:0010020 name: cardiac glial cell is_a: CL:0000125 ! glial cell is_a: CL:0002494 ! cardiocyte is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000125 ! glial cell intersection_of: BFO:0000050 UBERON:0000948 ! part of heart relationship: BFO:0000050 UBERON:0000948 ! part of heart [Term] id: CL:0010021 name: cardiac myoblast xref: MESH:D032386 is_a: CL:0000056 ! myoblast intersection_of: CL:0000056 ! myoblast intersection_of: RO:0002203 CL:0000746 ! develops into cardiac muscle cell relationship: RO:0002203 CL:0000746 ! develops into cardiac muscle cell [Term] id: CL:0010022 name: cardiac neuron def: "A neuron that has its soma in the heart." [PMID:12486170, PMID:29265764] is_a: CL:0000540 ! neuron intersection_of: CL:0000540 ! neuron intersection_of: RO:0002100 UBERON:0000948 ! has soma location heart relationship: RO:0002100 UBERON:0000948 ! has soma location heart relationship: RO:0002202 CL:0000031 ! develops from neuroblast (sensu Vertebrata) [Term] id: CL:0011001 name: spinal cord motor neuron def: "A motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement." [GOC:nv] is_a: CL:0000100 ! motor neuron is_a: CL:2000029 ! central nervous system neuron intersection_of: CL:0000100 ! motor neuron intersection_of: RO:0002100 UBERON:0002240 ! has soma location spinal cord relationship: RO:0002100 UBERON:0002240 ! has soma location spinal cord [Term] id: CL:0011007 name: paraxial cell def: "A cell in the area of mesoderm in the neurulating embryo that flanks and forms simultaneously with the neural tube. The cells of this region give rise to somites." [GOC:NV, PMID:11687492] synonym: "paraxial mesoderm cell" EXACT [] synonym: "somitic mesoderm cell" EXACT [] is_a: CL:0000222 ! mesodermal cell intersection_of: CL:0000222 ! mesodermal cell intersection_of: BFO:0000050 UBERON:0003059 ! part of presomitic mesoderm relationship: BFO:0000050 UBERON:0003059 ! part of presomitic mesoderm [Term] id: CL:0011012 name: neural crest cell def: "A cell of the neural crest. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesynchymal transition and delamination to form migratory neural crest cells." [https://orcid.org/0000-0001-5208-3432, https://orcid.org/0000-0002-9900-7880] is_a: CL:0000048 ! multi fate stem cell is_a: CL:0002321 ! embryonic cell (metazoa) [Term] id: CL:0011013 name: motile sperm cell def: "A sperm cell that is cabaple of motion (motility)." [PMID:30612620] is_a: CL:0000019 ! sperm is_a: CL:0000219 ! motile cell intersection_of: CL:0000019 ! sperm intersection_of: RO:0002215 GO:0097722 ! capable of sperm motility relationship: RO:0002215 GO:0097722 ! capable of sperm motility [Term] id: CL:0011016 name: flagellated sperm cell def: "A motile sperm cell that contains a slender threadlike microscopic appendage that enables motion." [https://www.lexico.com/en/definition/flagellum, PMID:30612620] is_a: CL:0011013 ! motile sperm cell intersection_of: CL:0011013 ! motile sperm cell intersection_of: RO:0002215 GO:0030317 ! capable of flagellated sperm motility relationship: RO:0002215 GO:0030317 ! capable of flagellated sperm motility [Term] id: CL:0011019 name: mesothelial cell of epicardium def: "A mesothelial cell that is part of the epicardium." [] is_a: CL:0000077 ! mesothelial cell is_a: CL:0002494 ! cardiocyte intersection_of: CL:0000077 ! mesothelial cell intersection_of: BFO:0000050 UBERON:0002348 ! part of epicardium relationship: BFO:0000050 UBERON:0002348 ! part of epicardium [Term] id: CL:0011021 name: fibroblast of upper back skin def: "A fibroblast that is part of upper back skin." [] is_a: CL:0011022 ! fibroblast of skin of back intersection_of: CL:0000057 ! fibroblast intersection_of: BFO:0000050 UBERON:0009015 ! part of upper back skin relationship: BFO:0000050 UBERON:0009015 ! part of upper back skin [Term] id: CL:0011022 name: fibroblast of skin of back def: "A fibroblast that is part of skin of back." [] is_a: CL:0002620 ! skin fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: BFO:0000050 UBERON:0001068 ! part of skin of back relationship: BFO:0000050 UBERON:0001068 ! part of skin of back [Term] id: CL:0011026 name: progenitor cell def: "A precursor cell that has a tendency to differentiate into a specific type of cell. They are descendants of stem cells, only they are more constrained in their differentiation potential or capacity for self-renewal, and are often more limited in both senses." [https://doi.org/10.1016/B978-0-12-409503-8.00002-0, ISBN:978-1-62808-994-3] is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011115 ! precursor cell intersection_of: CL:0011115 ! precursor cell intersection_of: RO:0002202 CL:0000034 ! develops from stem cell relationship: RO:0002202 CL:0000034 ! develops from stem cell [Term] id: CL:0011027 name: skeletal muscle fibroblast def: "Any fibroblast that is part of skeletal muscle tissue." [https://orcid.org/0000-0001-6164-0667, PMID:28369879] synonym: "skeleton muscle fibroblast" EXACT [] is_a: CL:0000188 ! cell of skeletal muscle is_a: CL:1001609 ! muscle fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: BFO:0000050 UBERON:0001134 ! part of skeletal muscle tissue [Term] id: CL:0011030 name: dermal microvascular endothelial cell def: "Any microvascular endothelial cell that is part of the dermis." [BTO:0004574, CL:patterns/cellPartOfAnatomicalEntity] synonym: "dermal microvascular endothelium cell" EXACT [] synonym: "DMEC cell" EXACT [] is_a: CL:2000008 ! microvascular endothelial cell is_a: CL:2000010 ! dermis blood vessel endothelial cell intersection_of: CL:2000008 ! microvascular endothelial cell intersection_of: BFO:0000050 UBERON:0002067 ! part of dermis [Term] id: CL:0011101 name: chorionic trophoblast cell def: "Cells of the uterine chorion that acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer." [GOC:NV] is_a: CL:0000351 ! trophoblast cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000351 ! trophoblast cell intersection_of: BFO:0000050 UBERON:0003124 ! part of chorion membrane relationship: BFO:0000050 UBERON:0003124 ! part of chorion membrane [Term] id: CL:0011108 name: colon epithelial cell def: "Epithelial cell that is part of the colon epithelium." [GOC:NV] synonym: "colonic epithelial cell" EXACT [] is_a: CL:0002253 ! epithelial cell of large intestine intersection_of: CL:0000066 ! epithelial cell intersection_of: BFO:0000050 UBERON:0001155 ! part of colon relationship: BFO:0000050 UBERON:0000397 ! part of colonic epithelium [Term] id: CL:0011115 name: precursor cell def: "A cell that, by division or terminal differentiation, can give rise to other cell types." [GOC:dos] is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: RO:0002215 GO:0030154 ! capable of cell differentiation relationship: RO:0002215 GO:0030154 ! capable of cell differentiation [Term] id: CL:0017500 name: neutrophillic cytoplasm def: "Cytoplasm that exhibits a characteristic staining and color, pale-pink, with Wright-Giemsa stain." [GOC:add] is_a: GO:0005737 ! cytoplasm intersection_of: GO:0005737 ! cytoplasm intersection_of: RO:0000053 PATO:0070046 ! has characteristic neutrophillic relationship: RO:0000053 PATO:0070046 ! has characteristic neutrophillic creation_date: 2010-05-25T01:36:34Z [Term] id: CL:0017502 name: acidophilic cytoplasm def: "Cytoplasm that exhibits a characteristic staining and color, red or pink, with Eosin stain." [GOC:add] is_a: GO:0005737 ! cytoplasm intersection_of: GO:0005737 ! cytoplasm intersection_of: RO:0000053 PATO:0002418 ! has characteristic acidophilic relationship: RO:0000053 PATO:0002418 ! has characteristic acidophilic creation_date: 2009-12-22T04:23:25Z [Term] id: CL:0017503 name: basophilic cytoplasm def: "Cytoplasm that exhibits molecular interaction for basic dyes under specific pH conditions." [GOC:tfm] is_a: GO:0005737 ! cytoplasm intersection_of: GO:0005737 ! cytoplasm intersection_of: RO:0000053 PATO:0002094 ! has characteristic basophilic relationship: RO:0000053 PATO:0002094 ! has characteristic basophilic creation_date: 2009-12-22T04:24:54Z [Term] id: CL:0017504 name: polychromatophilic cytoplasm def: "Cytoplasm that exhibits affinity for both basic and acid stains under specific pH conditions." [GOC:tfm] is_a: GO:0005737 ! cytoplasm intersection_of: GO:0005737 ! cytoplasm intersection_of: RO:0000053 PATO:0070047 ! has characteristic polychromatophilic relationship: RO:0000053 PATO:0070047 ! has characteristic polychromatophilic creation_date: 2009-12-28T04:25:23Z [Term] id: CL:0019018 name: blood vessel smooth muscle cell def: "A smooth muscle cell that is part of any blood vessel." [PMID:9108778] synonym: "smooth muscle cell of blood vessel" EXACT [] is_a: CL:0000359 ! vascular associated smooth muscle cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: BFO:0000050 UBERON:0001981 ! part of blood vessel relationship: BFO:0000050 UBERON:0001981 ! part of blood vessel [Term] id: CL:0019020 name: extrahepatic cholangiocyte def: "An epithelial cell of the extrahepatic bile ducts, including the left and right hepatic duct, common hepatic duct, and common bile duct. They are columnar in shape, and have a large nuclear-to-cytoplasmic ratio relative to small/intrahepatic cholangiocytes." [PMID:23720296] synonym: "large bile duct cholangiocyte" EXACT [PMID:23720296] is_a: CL:1000488 ! cholangiocyte intersection_of: CL:1000488 ! cholangiocyte intersection_of: BFO:0000050 UBERON:0004822 ! part of extrahepatic bile duct epithelium relationship: BFO:0000050 UBERON:0004822 ! part of extrahepatic bile duct epithelium [Term] id: CL:0019021 name: endothelial cell of periportal hepatic sinusoid def: "An endothelial cell found in the periportal region hepatic sinusoid, near the portal triad. The fenestrae of these cells are larger but fewer in number compared with those of endothelial cells near the centrilobular region of the hepatic sinusoid." [PMID:27423426] synonym: "periportal hepatic sinusoidal endothelial cell" EXACT [PMID:30348985] synonym: "periportal LSEC" EXACT [PMID:28287163] xref: EFO:0010705 is_a: CL:1000398 ! endothelial cell of hepatic sinusoid intersection_of: CL:1000398 ! endothelial cell of hepatic sinusoid intersection_of: RO:0002220 UBERON:0001279 ! adjacent to portal triad relationship: RO:0002220 UBERON:0001279 ! adjacent to portal triad [Term] id: CL:0019022 name: endothelial cell of pericentral hepatic sinusoid def: "An endothelial cell found in the centrilobular region hepatic sinusoid, near the central vein. The fenestrae of these cells are smaller but more numerous compared with those of endothelial cells near the periportal region of the hepatic sinusoid." [PMID:27423426] synonym: "central venous hepatic sinusoidal endothelial cell" EXACT [PMID:30348985] synonym: "pericentral LSEC" EXACT [PMID:28287163] xref: EFO:0010706 is_a: CL:1000398 ! endothelial cell of hepatic sinusoid intersection_of: CL:1000398 ! endothelial cell of hepatic sinusoid intersection_of: RO:0002220 UBERON:0006841 ! adjacent to central vein of liver relationship: RO:0002220 UBERON:0006841 ! adjacent to central vein of liver [Term] id: CL:1000090 name: pronephric nephron tubule epithelial cell is_a: CL:1000449 ! epithelial cell of nephron is_a: CL:1000507 ! kidney tubule cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000066 ! epithelial cell intersection_of: BFO:0000050 UBERON:0005310 ! part of pronephric nephron tubule relationship: BFO:0000050 UBERON:0005310 ! part of pronephric nephron tubule [Term] id: CL:1000123 name: metanephric nephron tubule epithelial cell is_a: CL:1000449 ! epithelial cell of nephron is_a: CL:1000507 ! kidney tubule cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000066 ! epithelial cell intersection_of: BFO:0000050 UBERON:0005146 ! part of metanephric nephron tubule relationship: BFO:0000050 UBERON:0005146 ! part of metanephric nephron tubule [Term] id: CL:1000222 name: stomach neuroendocrine cell is_a: CL:0000164 ! enteroendocrine cell is_a: CL:0000165 ! neuroendocrine cell is_a: CL:0002659 ! glandular cell of stomach intersection_of: CL:0000165 ! neuroendocrine cell intersection_of: BFO:0000050 UBERON:0000945 ! part of stomach relationship: RO:0002202 CL:0000031 ! develops from neuroblast (sensu Vertebrata) [Term] id: CL:1000223 name: lung neuroendocrine cell def: "A neuroendocrine cell that is part of respiratory epithelium of the lung and is involved in the sensory detection of environmental stimuli, including hypoxia, nicotine and air pressure. Ultrastructurally, this cell type is characterized by the presence of cytoplasmic dense core granules, which are considered the storage sites of amine and peptide hormones. Lung neuroendocrine cells are innervated and appear as solitary cells or as clustered masses, localized at airway bifurcation sites, called neuroepithelial bodies that can release serotonin in response to hypoxia and interact with sensory nerve terminals. Lung neuroendocrine cells also function as reserve stem cells that repair the surrounding epithelium after injury." [doi:10.3109/01902148209069653, doi:10.7554/eLife.78216, PMID:33355253] synonym: "pulmonary neuroendocrine cell" EXACT [PMID:33355253] is_a: CL:0000006 ! neuronal receptor cell is_a: CL:0000082 ! epithelial cell of lung is_a: CL:0000098 ! sensory epithelial cell is_a: CL:0000165 ! neuroendocrine cell is_a: CL:0000206 ! chemoreceptor cell is_a: CL:0000458 ! serotonin secreting cell is_a: CL:1000272 ! lung secretory cell intersection_of: CL:0000165 ! neuroendocrine cell intersection_of: BFO:0000050 UBERON:0002048 ! part of lung relationship: BFO:0000051 GO:0031045 ! has part dense core granule relationship: RO:0002202 CL:0000031 ! develops from neuroblast (sensu Vertebrata) relationship: RO:0002215 GO:0070483 ! capable of detection of hypoxia [Term] id: CL:1000271 name: lung ciliated cell is_a: CL:4030034 ! respiratory ciliated cell intersection_of: CL:0000064 ! ciliated cell intersection_of: BFO:0000050 UBERON:0002048 ! part of lung relationship: BFO:0000050 UBERON:0002048 ! part of lung [Term] id: CL:1000272 name: lung secretory cell is_a: CL:0000151 ! secretory cell is_a: CL:0000255 ! eukaryotic cell is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: CL:0000151 ! secretory cell intersection_of: BFO:0000050 UBERON:0002048 ! part of lung relationship: BFO:0000050 UBERON:0002048 ! part of lung [Term] id: CL:1000274 name: trophectodermal cell synonym: "trophectoderm cell" EXACT [] is_a: CL:0000349 ! extraembryonic cell [Term] id: CL:1000275 name: smooth muscle cell of small intestine def: "A smooth muscle cell that is part of the small intestine." [GOC:tfm] synonym: "non-striated muscle fiber of small intestine" EXACT [FMA:15050] xref: FMA:15050 is_a: CL:0002504 ! enteric smooth muscle cell intersection_of: CL:0002504 ! enteric smooth muscle cell intersection_of: BFO:0000050 UBERON:0002108 ! part of small intestine relationship: BFO:0000050 UBERON:0002108 ! part of small intestine [Term] id: CL:1000276 name: smooth muscle fiber of duodenum def: "A smooth muscle cell that is part of the duodenum." [GOC:tfm] synonym: "non-striated muscle fiber of duodenum" EXACT [FMA:15058] xref: FMA:15058 is_a: CL:1000275 ! smooth muscle cell of small intestine intersection_of: CL:1000275 ! smooth muscle cell of small intestine intersection_of: BFO:0000050 UBERON:0002114 ! part of duodenum relationship: BFO:0000050 UBERON:0002114 ! part of duodenum [Term] id: CL:1000279 name: smooth muscle cell of large intestine def: "A smooth muscle cell that is part of the large intestine." [GOC:tfm] synonym: "non-striated muscle fiber of large intestine" EXACT [FMA:15653] xref: FMA:15653 is_a: CL:0002504 ! enteric smooth muscle cell intersection_of: CL:0002504 ! enteric smooth muscle cell intersection_of: BFO:0000050 UBERON:0000059 ! part of large intestine relationship: BFO:0000050 UBERON:0000059 ! part of large intestine [Term] id: CL:1000280 name: smooth muscle cell of colon def: "A smooth muscle cell that is part of the colon." [GOC:tfm] synonym: "non-striated muscle fiber of colon" EXACT [FMA:15663] xref: FMA:15663 is_a: CL:1000279 ! smooth muscle cell of large intestine intersection_of: CL:0002504 ! enteric smooth muscle cell intersection_of: BFO:0000050 UBERON:0001155 ! part of colon relationship: BFO:0000050 UBERON:0001155 ! part of colon [Term] id: CL:1000285 name: smooth muscle cell of sigmoid colon def: "A smooth muscle cell that is part of the sigmoid colon." [GOC:tfm] synonym: "non-striated muscle fiber of sigmoid colon" EXACT [FMA:17521] xref: FMA:17521 is_a: CL:1000280 ! smooth muscle cell of colon intersection_of: CL:1000280 ! smooth muscle cell of colon intersection_of: BFO:0000050 UBERON:0001159 ! part of sigmoid colon relationship: BFO:0000050 UBERON:0001159 ! part of sigmoid colon [Term] id: CL:1000286 name: smooth muscle cell of rectum def: "A smooth muscle cell that is part of the rectum." [GOC:tfm] synonym: "non-striated muscle fiber of rectum" EXACT [FMA:17522] synonym: "smooth muscle fiber of rectum" EXACT [] xref: FMA:17522 is_a: CL:1000279 ! smooth muscle cell of large intestine intersection_of: CL:0000192 ! smooth muscle cell intersection_of: BFO:0000050 UBERON:0001052 ! part of rectum relationship: BFO:0000050 UBERON:0001052 ! part of rectum [Term] id: CL:1000296 name: epithelial cell of urethra def: "An epithelial cell that is part of the urethra." [GOC:tfm] xref: FMA:256165 is_a: CL:0000066 ! epithelial cell is_a: CL:1001320 ! urethra cell intersection_of: CL:0000066 ! epithelial cell intersection_of: BFO:0000050 UBERON:0000057 ! part of urethra [Term] id: CL:1000303 name: fibroblast of areolar connective tissue def: "A fibroblast that is part of the areolar connective tissue." [GOC:tfm] xref: FMA:261279 is_a: CL:0000057 ! fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: BFO:0000050 UBERON:0006815 ! part of areolar connective tissue relationship: BFO:0000050 UBERON:0006815 ! part of areolar connective tissue [Term] id: CL:1000306 name: fibroblast of tunica adventitia of artery def: "A fibroblast that is part of the tunica adventitia of artery." [GOC:tfm] xref: FMA:261285 is_a: CL:0000057 ! fibroblast is_a: CL:0002503 ! adventitial cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000057 ! fibroblast intersection_of: BFO:0000050 UBERON:0005734 ! part of tunica adventitia of blood vessel relationship: BFO:0000050 UBERON:0005734 ! part of tunica adventitia of blood vessel [Term] id: CL:1000307 name: fibroblast of dense regular elastic tissue def: "A fibroblast that is part of the dense regular elastic tissue." [GOC:tfm] xref: FMA:261287 is_a: CL:0000057 ! fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: BFO:0000050 UBERON:0007846 ! part of dense regular connective tissue relationship: BFO:0000050 UBERON:0002521 ! part of elastic tissue relationship: BFO:0000050 UBERON:0007846 ! part of dense regular connective tissue [Term] id: CL:1000309 name: epicardial adipocyte def: "An adipocyte that is part of the epicardial fat." [GOC:tfm] synonym: "adipocyte of epicardial fat" EXACT [FMA:261293] synonym: "epicardial fat cell" EXACT [FMA:261293] xref: FMA:261293 is_a: CL:0000136 ! adipocyte is_a: CL:0002494 ! cardiocyte is_a: UBERON:0004120 ! mesoderm-derived structure relationship: BFO:0000050 UBERON:0002348 ! part of epicardium [Term] id: CL:1000310 name: adipocyte of epicardial fat of right ventricle def: "An adipocyte that is part of the epicardial fat of right ventricle." [GOC:tfm] synonym: "epicardial adipocyte of right ventricle" EXACT [FMA:261297] synonym: "epicardial fat cell of right ventricle" EXACT [FMA:261297] xref: FMA:261297 is_a: CL:1000309 ! epicardial adipocyte intersection_of: CL:1000309 ! epicardial adipocyte intersection_of: BFO:0000050 UBERON:0002080 ! part of heart right ventricle relationship: BFO:0000050 UBERON:0002080 ! part of heart right ventricle [Term] id: CL:1000311 name: adipocyte of epicardial fat of left ventricle def: "An adipocyte that is part of the epicardial fat of left ventricle." [GOC:tfm] synonym: "epicardial adipocyte of left ventricle" EXACT [FMA:261300] synonym: "epicardial fat cell of left ventricle" EXACT [FMA:261300] xref: FMA:261300 is_a: CL:1000309 ! epicardial adipocyte intersection_of: CL:1000309 ! epicardial adipocyte intersection_of: BFO:0000050 UBERON:0002084 ! part of heart left ventricle relationship: BFO:0000050 UBERON:0002084 ! part of heart left ventricle [Term] id: CL:1000361 name: transitional myocyte of interatrial septum def: "A transitional myocyte that is part of the interatrial septum." [GOC:tfm] xref: FMA:263152 is_a: CL:0002073 ! transitional myocyte is_a: CL:2000022 ! cardiac septum cell intersection_of: CL:0002073 ! transitional myocyte intersection_of: BFO:0000050 UBERON:0002085 ! part of interatrial septum relationship: BFO:0000050 UBERON:0002085 ! part of interatrial septum [Term] id: CL:1000362 name: transitional myocyte of interventricular septum def: "A transitional myocyte that is part of the interventricular septum." [GOC:tfm] xref: FMA:263154 is_a: CL:0002073 ! transitional myocyte is_a: CL:2000022 ! cardiac septum cell intersection_of: CL:0002073 ! transitional myocyte intersection_of: BFO:0000050 UBERON:0002094 ! part of interventricular septum relationship: BFO:0000050 UBERON:0002094 ! part of interventricular septum [Term] id: CL:1000376 name: Purkinje myocyte of interventricular septum def: "A Purkinje myocyte that is part of the interventricular septum." [GOC:tfm] xref: FMA:263182 is_a: CL:0002068 ! Purkinje myocyte is_a: CL:2000022 ! cardiac septum cell intersection_of: CL:0002068 ! Purkinje myocyte intersection_of: BFO:0000050 UBERON:0002094 ! part of interventricular septum relationship: BFO:0000050 UBERON:0002094 ! part of interventricular septum [Term] id: CL:1000398 name: endothelial cell of hepatic sinusoid def: "An endothelial cell that is part of the hepatic sinusoid. These cells possess flattened areas containing perforations about 0.1 micrometers in diameter, known as fenestrae. The fenestrae are arranged in groups known as sieve plates." [GOC:tfm, PMID:3926620] synonym: "endotheliocyte of hepatic sinusoid" EXACT [FMA:62911] synonym: "liver sinusoidal endothelial cell" EXACT [PMID:30348985] synonym: "LSEC" EXACT [PMID:30348985] xref: BTO:000125 xref: FMA:62911 is_a: CL:0002262 ! endothelial cell of sinusoid is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure intersection_of: CL:0000115 ! endothelial cell intersection_of: BFO:0000050 UBERON:0001281 ! part of hepatic sinusoid relationship: BFO:0000050 UBERON:0001281 ! part of hepatic sinusoid [Term] id: CL:1000409 name: myocyte of sinoatrial node def: "A muscle cell that is part of the sinoatrial node." [FMA:67102, GOC:tfm] synonym: "SA nodal myocyte" EXACT [FMA:67102] synonym: "SA node cardiac muscle cell" EXACT [GOC:pr] synonym: "sinoatrial node cell" EXACT [GOC:pr] synonym: "sinoatrial node myocyte" EXACT [] synonym: "sinuatrial node myocyte" EXACT [FMA:67102] xref: FMA:67102 is_a: CL:0002072 ! nodal myocyte is_a: CL:0008009 ! transversely striated visceral muscle cell intersection_of: CL:0000187 ! muscle cell intersection_of: BFO:0000050 UBERON:0002351 ! part of sinoatrial node relationship: BFO:0000050 UBERON:0002351 ! part of sinoatrial node [Term] id: CL:1000410 name: myocyte of atrioventricular node def: "A muscle cell that is part of the atrioventricular node." [FMA:67106, GOC:tfm] synonym: "atrioventricular node cell" EXACT [GOC:pr] synonym: "atrioventricular node myocyte" EXACT [FMA:67106] synonym: "AV nodal myocyte" EXACT [FMA:67106] synonym: "AV node cardiac muscle cell" EXACT [GOC:pr] synonym: "AV node cell" EXACT [GOC:pr] xref: FMA:67106 is_a: CL:0002072 ! nodal myocyte is_a: CL:0008009 ! transversely striated visceral muscle cell is_a: CL:2000022 ! cardiac septum cell intersection_of: CL:0000187 ! muscle cell intersection_of: BFO:0000050 UBERON:0002352 ! part of atrioventricular node relationship: BFO:0000050 UBERON:0002352 ! part of atrioventricular node [Term] id: CL:1000412 name: endothelial cell of arteriole def: "An endothelial cell that is part of the arteriole." [GOC:tfm] xref: FMA:67760 xref: KUPO:0001097 is_a: CL:0000071 ! blood vessel endothelial cell intersection_of: CL:0000115 ! endothelial cell intersection_of: BFO:0000050 UBERON:0001980 ! part of arteriole relationship: BFO:0000050 UBERON:0001980 ! part of arteriole [Term] id: CL:1000413 name: endothelial cell of artery def: "A blood vessel endothelial cell that is part of an arterial endothelium." [GOC:tfm] synonym: "arterial endothelial cell" EXACT [] xref: BTO:0004758 xref: FMA:67761 xref: KUPO:0001095 is_a: CL:0000071 ! blood vessel endothelial cell intersection_of: CL:0000115 ! endothelial cell intersection_of: BFO:0000050 UBERON:0001637 ! part of artery relationship: BFO:0000050 UBERON:0001917 ! part of endothelium of artery [Term] id: CL:1000414 name: endothelial cell of venule def: "An endothelial cell that is part of the venule." [GOC:tfm] xref: FMA:67762 is_a: CL:0002139 ! endothelial cell of vascular tree intersection_of: CL:0002139 ! endothelial cell of vascular tree intersection_of: BFO:0000050 UBERON:0001979 ! part of venule relationship: BFO:0000050 UBERON:0001979 ! part of venule [Term] id: CL:1000415 name: epithelial cell of gallbladder def: "An epithelial cell that is part of the gallbladder." [GOC:tfm] xref: FMA:67780 is_a: CL:0000066 ! epithelial cell is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: CL:0000066 ! epithelial cell intersection_of: BFO:0000050 UBERON:0002110 ! part of gallbladder relationship: BFO:0000050 UBERON:0002110 ! part of gallbladder [Term] id: CL:1000428 name: stem cell of epidermis def: "A somatic stem cell that is part of the epidermis." [GOC:tfm] synonym: "epidermal stem cell" EXACT [FMA:70541] xref: FMA:70541 is_a: CL:0000723 ! somatic stem cell is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:0000723 ! somatic stem cell intersection_of: BFO:0000050 UBERON:0001003 ! part of skin epidermis relationship: BFO:0000050 UBERON:0001003 ! part of skin epidermis [Term] id: CL:1000443 name: ciliary muscle cell def: "A smooth muscle cell that is part of the ciliary body." [GOC:tfm] synonym: "smooth muscle cell of ciliary body" EXACT [FMA:70610] xref: FMA:70610 is_a: CL:0000192 ! smooth muscle cell is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:0000192 ! smooth muscle cell intersection_of: BFO:0000050 UBERON:0001775 ! part of ciliary body relationship: BFO:0000050 UBERON:0001775 ! part of ciliary body [Term] id: CL:1000444 name: mesothelial cell of anterior chamber of eye def: "A mesothelial cell that is part of the anterior chamber of eyeball." [GOC:tfm] xref: FMA:70615 is_a: CL:0000077 ! mesothelial cell is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:0000077 ! mesothelial cell intersection_of: BFO:0000050 UBERON:0001766 ! part of anterior chamber of eyeball relationship: BFO:0000050 UBERON:0001766 ! part of anterior chamber of eyeball [Term] id: CL:1000449 name: epithelial cell of nephron def: "An epithelial cell that is part of the nephron." [GOC:tfm] xref: FMA:70965 is_a: CL:0002518 ! kidney epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: BFO:0000050 UBERON:0001285 ! part of nephron relationship: BFO:0000050 UBERON:0001285 ! part of nephron [Term] id: CL:1000454 name: kidney collecting duct epithelial cell def: "An epithelial cell that is part of the collecting duct of renal tubule." [GOC:tfm] synonym: "epithelial cell of renal collecting tubule" EXACT [FMA:70982] xref: FMA:70982 xref: KUPO:0001059 is_a: CL:0000072 ! non-branched duct epithelial cell is_a: CL:1000449 ! epithelial cell of nephron is_a: CL:1001225 ! kidney collecting duct cell intersection_of: CL:0000066 ! epithelial cell intersection_of: BFO:0000050 UBERON:0001232 ! part of collecting duct of renal tubule [Term] id: CL:1000456 name: mesothelial cell of parietal peritoneum def: "A mesothelial cell that is part of the parietal peritoneum." [GOC:tfm] xref: FMA:72142 is_a: CL:1000490 ! mesothelial cell of peritoneum intersection_of: CL:0000077 ! mesothelial cell intersection_of: BFO:0000050 UBERON:0001366 ! part of parietal peritoneum relationship: BFO:0000050 UBERON:0001366 ! part of parietal peritoneum [Term] id: CL:1000457 name: mesothelial cell of visceral peritoneum def: "A mesothelial cell that is part of the visceral peritoneum." [GOC:tfm] xref: FMA:72143 is_a: CL:1000490 ! mesothelial cell of peritoneum intersection_of: CL:0000077 ! mesothelial cell intersection_of: BFO:0000050 UBERON:0001178 ! part of visceral peritoneum relationship: BFO:0000050 UBERON:0001178 ! part of visceral peritoneum [Term] id: CL:1000478 name: transitional myocyte of sinoatrial node def: "A transitional myocyte that is part of the sinoatrial node." [GOC:tfm] synonym: "transitinal myocyte of sinuatrial node" EXACT [] xref: FMA:83384 is_a: CL:0002073 ! transitional myocyte is_a: CL:1000409 ! myocyte of sinoatrial node intersection_of: CL:0002073 ! transitional myocyte intersection_of: BFO:0000050 UBERON:0002351 ! part of sinoatrial node [Term] id: CL:1000479 name: Purkinje myocyte of atrioventricular node def: "A Purkinje myocyte that is part of the atrioventricular node." [GOC:tfm] xref: FMA:83386 is_a: CL:0002068 ! Purkinje myocyte is_a: CL:1000410 ! myocyte of atrioventricular node intersection_of: CL:0002068 ! Purkinje myocyte intersection_of: BFO:0000050 UBERON:0002352 ! part of atrioventricular node [Term] id: CL:1000482 name: myocardial endocrine cell of interventricular septum def: "A myocardial endocrine cell that is part of the interventricular septum." [GOC:tfm] xref: FMA:83390 is_a: CL:0002074 ! myocardial endocrine cell is_a: CL:2000022 ! cardiac septum cell intersection_of: CL:0002074 ! myocardial endocrine cell intersection_of: BFO:0000050 UBERON:0002094 ! part of interventricular septum relationship: BFO:0000050 UBERON:0002094 ! part of interventricular septum [Term] id: CL:1000488 name: cholangiocyte def: "An epithelial cell that is part of the bile duct. Cholangiocytes contribute to bile secretion via net release of bicarbonate and water. They are cuboidal epithelium in the small interlobular bile ducts, but become columnar and mucus secreting in larger bile ducts approaching the porta hepatis and the extrahepatic ducts." [GOC:tfm, PMID:16550043, PMID:18356246] synonym: "epithelial cell of bile duct" EXACT [] xref: FMA:86481 is_a: CL:0000069 ! branched duct epithelial cell is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: CL:0000069 ! branched duct epithelial cell intersection_of: BFO:0000050 UBERON:0002394 ! part of bile duct intersection_of: RO:0002215 GO:0015106 ! capable of bicarbonate transmembrane transporter activity relationship: BFO:0000050 UBERON:0002394 ! part of bile duct relationship: RO:0002202 CL:0005026 ! develops from hepatoblast [Term] id: CL:1000490 name: mesothelial cell of peritoneum def: "A mesothelial cell that is part of the peritoneum." [GOC:tfm] synonym: "peritoneal mesothelial cell" EXACT [FMA:86736] xref: FMA:86736 is_a: CL:0000077 ! mesothelial cell intersection_of: CL:0000077 ! mesothelial cell intersection_of: BFO:0000050 UBERON:0002358 ! part of peritoneum relationship: BFO:0000050 UBERON:0002358 ! part of peritoneum [Term] id: CL:1000491 name: mesothelial cell of pleura def: "A mesothelial cell that is part of the pleura." [GOC:tfm] synonym: "pleural mesothelial cell" EXACT [FMA:86737] xref: FMA:86737 is_a: CL:0000077 ! mesothelial cell is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure intersection_of: CL:0000077 ! mesothelial cell intersection_of: BFO:0000050 UBERON:0000977 ! part of pleura relationship: BFO:0000050 UBERON:0000977 ! part of pleura [Term] id: CL:1000492 name: mesothelial cell of parietal pleura def: "A mesothelial cell that is part of the parietal pleura." [GOC:tfm] xref: FMA:86738 is_a: CL:1000491 ! mesothelial cell of pleura intersection_of: CL:0000077 ! mesothelial cell intersection_of: BFO:0000050 UBERON:0002400 ! part of parietal pleura relationship: BFO:0000050 UBERON:0002400 ! part of parietal pleura [Term] id: CL:1000493 name: mesothelial cell of visceral pleura def: "A mesothelial cell that is part of the visceral pleura." [GOC:tfm] xref: FMA:86739 is_a: CL:0000082 ! epithelial cell of lung is_a: CL:1000491 ! mesothelial cell of pleura intersection_of: CL:0000077 ! mesothelial cell intersection_of: BFO:0000050 UBERON:0002401 ! part of visceral pleura relationship: BFO:0000050 UBERON:0002401 ! part of visceral pleura [Term] id: CL:1000494 name: nephron tubule epithelial cell def: "An epithelial cell that is part of a nephron tubule." [GOC:tfm] synonym: "kidney tubule epithelial cell" EXACT [] xref: FMA:86785 xref: KUPO:0001022 is_a: CL:1000449 ! epithelial cell of nephron is_a: CL:1000507 ! kidney tubule cell intersection_of: CL:0000066 ! epithelial cell intersection_of: BFO:0000050 UBERON:0004810 ! part of nephron tubule epithelium relationship: BFO:0000050 UBERON:0004810 ! part of nephron tubule epithelium [Term] id: CL:1000497 name: kidney cell def: "A cell that is part of a kidney." [] xref: KUPO:0001010 is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: BFO:0000050 UBERON:0002113 ! part of kidney relationship: BFO:0000050 UBERON:0002113 ! part of kidney [Term] id: CL:1000500 name: kidney interstitial cell def: "A cell that is part of kidney interstitium." [] xref: KUPO:0001013 is_a: CL:1000497 ! kidney cell is_a: CL:4030031 ! interstitial cell intersection_of: CL:1000497 ! kidney cell intersection_of: BFO:0000050 UBERON:0005215 ! part of kidney interstitium relationship: BFO:0000050 UBERON:0005215 ! part of kidney interstitium [Term] id: CL:1000505 name: kidney pelvis cell def: "A cell that is part of a renal pelvis." [] xref: KUPO:0001018 is_a: CL:1000497 ! kidney cell intersection_of: CL:1000497 ! kidney cell intersection_of: BFO:0000050 UBERON:0001224 ! part of renal pelvis relationship: BFO:0000050 UBERON:0001224 ! part of renal pelvis [Term] id: CL:1000507 name: kidney tubule cell def: "A cell that is part of a nephron tubule." [] xref: KUPO:0001020 is_a: CL:1000497 ! kidney cell intersection_of: CL:1000497 ! kidney cell intersection_of: BFO:0000050 UBERON:0001231 ! part of nephron tubule relationship: BFO:0000050 UBERON:0001231 ! part of nephron tubule [Term] id: CL:1000549 name: kidney cortex collecting duct epithelial cell def: "An epithelial cell that is part of a cortical collecting duct." [] xref: KUPO:0001063 is_a: CL:0002584 ! renal cortical epithelial cell is_a: CL:1000454 ! kidney collecting duct epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: BFO:0000050 UBERON:0004203 ! part of cortical collecting duct relationship: BFO:0000050 UBERON:0004203 ! part of cortical collecting duct [Term] id: CL:1000600 name: lower urinary tract cell xref: KUPO:0001115 is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: BFO:0000050 UBERON:0001556 ! part of lower urinary tract relationship: BFO:0000050 UBERON:0001556 ! part of lower urinary tract [Term] id: CL:1000601 name: ureteral cell xref: KUPO:0001116 is_a: CL:0000255 ! eukaryotic cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000000 ! cell intersection_of: BFO:0000050 UBERON:0000056 ! part of ureter relationship: BFO:0000050 UBERON:0000056 ! part of ureter [Term] id: CL:1000606 name: kidney nerve cell xref: KUPO:0001015 is_a: CL:1000500 ! kidney interstitial cell is_a: CL:2000032 ! peripheral nervous system neuron intersection_of: CL:0000540 ! neuron intersection_of: RO:0002100 UBERON:0002113 ! has soma location kidney relationship: RO:0002100 UBERON:0002113 ! has soma location kidney relationship: RO:0002202 CL:0000031 ! develops from neuroblast (sensu Vertebrata) [Term] id: CL:1000681 name: kidney cortex interstitial cell xref: KUPO:0001091 is_a: CL:0002584 ! renal cortical epithelial cell is_a: CL:1000500 ! kidney interstitial cell intersection_of: CL:1000500 ! kidney interstitial cell intersection_of: BFO:0000050 UBERON:0005270 ! part of renal cortex interstitium relationship: BFO:0000050 UBERON:0005270 ! part of renal cortex interstitium [Term] id: CL:1000692 name: kidney interstitial fibroblast xref: KUPO:0001102 is_a: CL:0000057 ! fibroblast is_a: CL:1000500 ! kidney interstitial cell intersection_of: CL:0000057 ! fibroblast intersection_of: BFO:0000050 UBERON:0005215 ! part of kidney interstitium [Term] id: CL:1000702 name: kidney pelvis smooth muscle cell xref: KUPO:0001113 is_a: CL:0000192 ! smooth muscle cell is_a: CL:1000505 ! kidney pelvis cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: BFO:0000050 UBERON:0004227 ! part of kidney pelvis smooth muscle relationship: BFO:0000050 UBERON:0004227 ! part of kidney pelvis smooth muscle [Term] id: CL:1000708 name: ureter adventitial cell xref: KUPO:0001119 is_a: CL:0000115 ! endothelial cell is_a: CL:0002503 ! adventitial cell is_a: CL:1000601 ! ureteral cell intersection_of: CL:1000601 ! ureteral cell intersection_of: BFO:0000050 UBERON:0001252 ! part of adventitia of ureter relationship: BFO:0000050 UBERON:0001252 ! part of adventitia of ureter [Term] id: CL:1000714 name: kidney cortex collecting duct principal cell xref: KUPO:0001130 is_a: CL:1000549 ! kidney cortex collecting duct epithelial cell is_a: CL:1001431 ! kidney collecting duct principal cell intersection_of: CL:0005009 ! renal principal cell intersection_of: BFO:0000050 UBERON:0004203 ! part of cortical collecting duct [Term] id: CL:1000979 name: ureter smooth muscle cell xref: KUPO:0001118 is_a: CL:0000192 ! smooth muscle cell is_a: CL:1000601 ! ureteral cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: BFO:0000050 UBERON:0006855 ! part of muscular coat of ureter relationship: BFO:0000050 UBERON:0006855 ! part of muscular coat of ureter [Term] id: CL:1001225 name: kidney collecting duct cell def: "A cell that is part of a collecting duct of renal tubule." [] xref: KUPO:0001012 xref: Wikipedia:Kidney_collecting_duct_cell is_a: CL:1000497 ! kidney cell intersection_of: CL:1000497 ! kidney cell intersection_of: BFO:0000050 UBERON:0001232 ! part of collecting duct of renal tubule relationship: BFO:0000050 UBERON:0001232 ! part of collecting duct of renal tubule [Term] id: CL:1001319 name: bladder cell xref: KUPO:0001120 is_a: CL:1000600 ! lower urinary tract cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000000 ! cell intersection_of: BFO:0000050 UBERON:0001255 ! part of urinary bladder relationship: BFO:0000050 UBERON:0001255 ! part of urinary bladder [Term] id: CL:1001320 name: urethra cell xref: KUPO:0001123 is_a: CL:1000600 ! lower urinary tract cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000000 ! cell intersection_of: BFO:0000050 UBERON:0000057 ! part of urethra relationship: BFO:0000050 UBERON:0000057 ! part of urethra [Term] id: CL:1001431 name: kidney collecting duct principal cell xref: KUPO:0001128 is_a: CL:0005009 ! renal principal cell is_a: CL:1000454 ! kidney collecting duct epithelial cell intersection_of: CL:0005009 ! renal principal cell intersection_of: BFO:0000050 UBERON:0001232 ! part of collecting duct of renal tubule [Term] id: CL:1001433 name: epithelial cell of exocrine pancreas def: "An epithelial cell of the exocrine pancreas." [GOC:tfm] synonym: "exocrine pancreas cell" EXACT [] xref: FMA:70986 is_a: CL:0000083 ! epithelial cell of pancreas intersection_of: CL:0000066 ! epithelial cell intersection_of: BFO:0000050 UBERON:0000017 ! part of exocrine pancreas relationship: BFO:0000050 UBERON:0000017 ! part of exocrine pancreas [Term] id: CL:1001516 name: intestinal enteroendocrine cell def: "The various hormone- or neurotransmitter-secreting cells present throughout the mucosa of the intestinal tract." [MP:0010802] is_a: CL:0000164 ! enteroendocrine cell is_a: CL:0002563 ! intestinal epithelial cell intersection_of: CL:0000164 ! enteroendocrine cell intersection_of: BFO:0000050 UBERON:0001242 ! part of intestinal mucosa [Term] id: CL:1001567 name: lung endothelial cell is_a: CL:0000082 ! epithelial cell of lung is_a: CL:0002139 ! endothelial cell of vascular tree is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure intersection_of: CL:0002139 ! endothelial cell of vascular tree intersection_of: BFO:0000050 UBERON:0002048 ! part of lung relationship: BFO:0000050 UBERON:0000102 ! part of lung vasculature [Term] id: CL:1001568 name: pulmonary artery endothelial cell xref: BTO:0001141 is_a: CL:1000413 ! endothelial cell of artery intersection_of: CL:0002139 ! endothelial cell of vascular tree intersection_of: BFO:0000050 UBERON:0002012 ! part of pulmonary artery relationship: BFO:0000050 UBERON:0005317 ! part of pulmonary artery endothelium [Term] id: CL:1001572 name: colon endothelial cell def: "A vascular endothelial cell found in colon blood vessels." [https://orcid.org/0000-0001-5208-3432, NPX:PDR] xref: CALOHA:TS-2397 is_a: CL:0000115 ! endothelial cell is_a: CL:0011108 ! colon epithelial cell is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure intersection_of: CL:0000115 ! endothelial cell intersection_of: BFO:0000050 UBERON:0001155 ! part of colon relationship: BFO:0000050 UBERON:0013695 ! part of colon endothelium [Term] id: CL:1001576 name: oral mucosa squamous cell def: "Squamous cell of oral epithelium." [NPX:PDR] xref: CALOHA:TS-1252 is_a: CL:0000076 ! squamous epithelial cell is_a: CL:0002251 ! epithelial cell of alimentary canal intersection_of: CL:0000076 ! squamous epithelial cell intersection_of: BFO:0000050 UBERON:0002424 ! part of oral epithelium relationship: BFO:0000050 UBERON:0002424 ! part of oral epithelium [Term] id: CL:1001588 name: colon glandular cell def: "Glandular cell of colon epithelium. Example: Goblet cells; enterocytes or absorptive cells; enteroendocrine and M cells." [NPX:PDR] xref: CALOHA:TS-1274 is_a: CL:0002658 ! glandular cell of the large intestine is_a: CL:0011108 ! colon epithelial cell intersection_of: CL:0000150 ! glandular epithelial cell intersection_of: BFO:0000050 UBERON:0001155 ! part of colon [Term] id: CL:1001589 name: duodenum glandular cell def: "Glandular cell of duodenal epithelium. Example: Enterocytes, Goblet cells, enteroendocrine cells; Paneth cells; M cells; Brunner's gland cell." [NPX:PDR] xref: CALOHA:TS-1275 is_a: CL:1001598 ! small intestine glandular cell intersection_of: CL:0000150 ! glandular epithelial cell intersection_of: BFO:0000050 UBERON:0002114 ! part of duodenum relationship: BFO:0000050 UBERON:0008346 ! part of duodenal epithelium [Term] id: CL:1001590 name: epididymis glandular cell def: "Glandular cell of epididymal epithelium." [NPX:PDR] xref: CALOHA:TS-1276 is_a: CL:0000068 ! duct epithelial cell is_a: CL:0000150 ! glandular epithelial cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000150 ! glandular epithelial cell intersection_of: BFO:0000050 UBERON:0001301 ! part of epididymis relationship: BFO:0000050 UBERON:0004544 ! part of epididymis epithelium [Term] id: CL:1001591 name: oviduct glandular cell def: "Glandular cell of oviduct epithelium. Example: peg cells, ciliated cells." [HPA:HPA, NPX:PDR] xref: CALOHA:TS-1277 is_a: CL:0000150 ! glandular epithelial cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000150 ! glandular epithelial cell intersection_of: CL:1100001 ! secretory epithelial cell intersection_of: BFO:0000050 UBERON:0000993 ! part of oviduct intersection_of: BFO:0000050 UBERON:0000993 ! part of oviduct relationship: BFO:0000050 UBERON:0004804 ! part of oviduct epithelium [Term] id: CL:1001592 name: gallbladder glandular cell def: "Glandular cell of gallbladder epithelium." [NPX:PDR] synonym: "gall bladder glandular cell" EXACT [FMA:7202] xref: CALOHA:TS-1278 is_a: CL:0000150 ! glandular epithelial cell is_a: CL:1000415 ! epithelial cell of gallbladder intersection_of: CL:0000150 ! glandular epithelial cell intersection_of: BFO:0000050 UBERON:0002110 ! part of gallbladder relationship: BFO:0000050 UBERON:0002029 ! part of epithelium of gall bladder [Term] id: CL:1001595 name: rectum glandular cell def: "Glandular cell of rectal epithelium. Example: Goblet cell; enterocytes or absorptive cells; enteroendocrine and M cells." [NPX:PDR] xref: CALOHA:TS-1281 is_a: CL:0002658 ! glandular cell of the large intestine intersection_of: CL:0000150 ! glandular epithelial cell intersection_of: BFO:0000050 UBERON:0001052 ! part of rectum relationship: BFO:0000050 UBERON:0003354 ! part of epithelium of rectum [Term] id: CL:1001597 name: seminal vesicle glandular cell def: "Glandular cell of seminal vesicle epithelium." [NPX:PDR] xref: CALOHA:TS-1283 is_a: CL:0000068 ! duct epithelial cell is_a: CL:0000150 ! glandular epithelial cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000150 ! glandular epithelial cell intersection_of: BFO:0000050 UBERON:0000998 ! part of seminal vesicle relationship: BFO:0000050 UBERON:0004805 ! part of seminal vesicle epithelium [Term] id: CL:1001598 name: small intestine glandular cell def: "A glandular cell found in the epithelium of the small intestine. Example: Enterocytes, Goblet cells, enteroendocrine cells; Paneth cells; M cells; Somatostatin-secreting Cells (D-cells) ." [NCI_Thesaurus:Small_Intestinal_Glandular_Cell, NPX:PDR] xref: CALOHA:TS-1286 xref: FMA:86928 is_a: CL:0000150 ! glandular epithelial cell is_a: CL:0002254 ! epithelial cell of small intestine intersection_of: CL:0000150 ! glandular epithelial cell intersection_of: BFO:0000050 UBERON:0002108 ! part of small intestine relationship: BFO:0000050 UBERON:0001902 ! part of epithelium of small intestine [Term] id: CL:1001599 name: pancreas exocrine glandular cell def: "Glandular cell of exocrine pancreas epithelium. Example: pancreatic acinar cell, glandular cells in pancreatic canaliculi, glandular cells in pancreatic ducts." [HPA:HPA, NPX:PDR] xref: BTO:0000028 xref: CALOHA:TS-1242 is_a: CL:0000150 ! glandular epithelial cell is_a: CL:0000152 ! exocrine cell is_a: CL:1001433 ! epithelial cell of exocrine pancreas intersection_of: CL:0000150 ! glandular epithelial cell intersection_of: BFO:0000050 UBERON:0000017 ! part of exocrine pancreas relationship: BFO:0000050 UBERON:0013697 ! part of exocrine pancreas epithelium [Term] id: CL:1001609 name: muscle fibroblast def: "Fibroblast from muscle organ." [NPX:PDR] xref: CALOHA:TS-0643 is_a: CL:0000057 ! fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: BFO:0000050 UBERON:0001630 ! part of muscle organ relationship: BFO:0000050 UBERON:0001630 ! part of muscle organ [Term] id: CL:1001610 name: bone marrow hematopoietic cell def: "Hematopoietic cells resident in the bone marrow. Include: hematopoietic stem cells (lymphoid stem cells and myeloid stem cells) and the precursor cells for thrombocytes, erythrocytes, basophils, neutrophils, eosinophils, monocytes and lymphocytes." [NPX:PDR] xref: CALOHA:TS-2109 is_a: CL:0000988 ! hematopoietic cell is_a: CL:0002092 ! bone marrow cell intersection_of: CL:0000988 ! hematopoietic cell intersection_of: BFO:0000050 UBERON:0002371 ! part of bone marrow relationship: BFO:0000050 UBERON:0012429 ! part of hematopoietic tissue [Term] id: CL:1100001 name: secretory epithelial cell def: "An epithelial cell that is specialised for the synthesis and secretion of specific biomolecules." [https://orcid.org/0000-0002-7073-9172] is_a: CL:0000066 ! epithelial cell is_a: CL:0000151 ! secretory cell intersection_of: CL:0000066 ! epithelial cell intersection_of: CL:0000151 ! secretory cell property_value: skos:prefLabel "secretory epithelial cell" xsd:string [Term] id: CL:2000001 name: peripheral blood mononuclear cell def: "A leukocyte with a single non-segmented nucleus in the mature form found in the circulatory pool of blood." [GOC:TermGenie] is_a: CL:0000080 ! circulating cell is_a: CL:0000842 ! mononuclear cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000842 ! mononuclear cell intersection_of: BFO:0000050 UBERON:0000178 ! part of blood relationship: BFO:0000050 UBERON:0000178 ! part of blood creation_date: 2014-02-11T17:29:04Z [Term] id: CL:2000002 name: decidual cell def: "A specialized, enlarged, connective tissue cell of the decidua with enlarged nucleus, dense membrane‐bound secretory granules and cytoplasmic accumulation of glycogen and lipid droplets. These cells develop by the transformation of endometrial stromal cells during decidualization." [BTO:0002770, NCIT:C32429, PMID:30013421, PMID:30429548, Wiki:Decidual_cells&oldid=937509751, Wiki:Decidualization&oldid=908981933] synonym: "decidua cell" EXACT [BTO:0002770, NCIT:C32429] synonym: "decidual stromal cell" EXACT [BTO:0005756, PMID:11719592] xref: BTO:0002770 xref: BTO:0005756 xref: NCIT:C32429 is_a: CL:0000349 ! extraembryonic cell is_a: CL:0000499 ! stromal cell is_a: UBERON:0004120 ! mesoderm-derived structure relationship: BFO:0000050 UBERON:0002450 ! part of decidua relationship: RO:0002202 CL:0002255 ! develops from stromal cell of endometrium creation_date: 2014-02-20T23:06:41Z [Term] id: CL:2000008 name: microvascular endothelial cell def: "Any blood vessel endothelial cell that is part of a microvascular endothelium." [GOC:TermGenie] is_a: CL:0000071 ! blood vessel endothelial cell intersection_of: CL:0000071 ! blood vessel endothelial cell intersection_of: BFO:0000050 UBERON:0008339 ! part of microvascular endothelium relationship: BFO:0000050 UBERON:0008339 ! part of microvascular endothelium creation_date: 2014-06-04T15:07:42Z [Term] id: CL:2000010 name: dermis blood vessel endothelial cell def: "Any blood vessel endothelial cell that is part of a dermis." [GOC:TermGenie] is_a: CL:0000071 ! blood vessel endothelial cell is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:0000071 ! blood vessel endothelial cell intersection_of: BFO:0000050 UBERON:0002067 ! part of dermis relationship: BFO:0000050 UBERON:0002067 ! part of dermis creation_date: 2014-06-04T15:12:06Z [Term] id: CL:2000013 name: fibroblast of skin of abdomen def: "Any skin fibroblast that is part of a skin of abdomen." [GOC:TermGenie] is_a: CL:0002620 ! skin fibroblast intersection_of: CL:0002620 ! skin fibroblast intersection_of: BFO:0000050 UBERON:0001416 ! part of skin of abdomen relationship: BFO:0000050 UBERON:0001416 ! part of skin of abdomen creation_date: 2014-06-04T15:18:16Z [Term] id: CL:2000016 name: lung microvascular endothelial cell def: "Any lung endothelial cell that is part of a microvascular endothelium." [GOC:TermGenie] is_a: CL:1001567 ! lung endothelial cell is_a: CL:2000008 ! microvascular endothelial cell intersection_of: CL:1001567 ! lung endothelial cell intersection_of: BFO:0000050 UBERON:0008339 ! part of microvascular endothelium creation_date: 2014-06-04T16:00:56Z [Term] id: CL:2000019 name: compound eye photoreceptor cell def: "Any photoreceptor cell that is part of a compound eye." [GOC:TermGenie] xref: FBbt:00004211 is_a: CL:0000287 ! eye photoreceptor cell intersection_of: CL:0000210 ! photoreceptor cell intersection_of: BFO:0000050 UBERON:0000018 ! part of compound eye relationship: BFO:0000050 UBERON:0000018 ! part of compound eye creation_date: 2014-06-24T23:16:45Z [Term] id: CL:2000020 name: inner cell mass cell def: "Any native cell that is part of a inner cell mass." [GOC:TermGenie] is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: BFO:0000050 UBERON:0000087 ! part of inner cell mass relationship: BFO:0000050 UBERON:0000087 ! part of inner cell mass creation_date: 2014-06-24T23:16:53Z [Term] id: CL:2000022 name: cardiac septum cell def: "Any native cell that is part of a cardiac septum." [GOC:TermGenie] is_a: CL:0002494 ! cardiocyte is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000000 ! cell intersection_of: BFO:0000050 UBERON:0002099 ! part of cardiac septum relationship: BFO:0000050 UBERON:0002099 ! part of cardiac septum creation_date: 2014-06-24T23:17:07Z [Term] id: CL:2000029 name: central nervous system neuron def: "Any neuron that is part of a central nervous system." [GOC:TermGenie] is_a: CL:0000540 ! neuron intersection_of: CL:0000540 ! neuron intersection_of: RO:0002100 UBERON:0001017 ! has soma location central nervous system relationship: RO:0002100 UBERON:0001017 ! has soma location central nervous system creation_date: 2014-06-25T01:17:43Z [Term] id: CL:2000032 name: peripheral nervous system neuron def: "A neuron that is part of a peripheral nervous system." [GOC:TermGenie, ISBN:0721662544] synonym: "peripheral neuron" EXACT [] synonym: "PNS neuron" EXACT [] xref: FMA:84664 is_a: CL:0000540 ! neuron intersection_of: CL:0000540 ! neuron intersection_of: RO:0002100 UBERON:0000010 ! has soma location peripheral nervous system relationship: RO:0002100 UBERON:0000010 ! has soma location peripheral nervous system creation_date: 2014-06-25T02:28:17Z [Term] id: CL:2000040 name: bladder microvascular endothelial cell def: "Any microvascular endothelial cell that is part of a urinary bladder." [GOC:TermGenie] is_a: CL:1001319 ! bladder cell is_a: CL:2000008 ! microvascular endothelial cell intersection_of: CL:2000008 ! microvascular endothelial cell intersection_of: BFO:0000050 UBERON:0001255 ! part of urinary bladder creation_date: 2014-07-09T00:04:47Z [Term] id: CL:2000042 name: embryonic fibroblast def: "Any fibroblast that is part of a embryo." [GOC:TermGenie] is_a: CL:0000057 ! fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: BFO:0000050 UBERON:0000922 ! part of embryo relationship: BFO:0000050 UBERON:0000922 ! part of embryo creation_date: 2014-07-09T00:12:00Z [Term] id: CL:2000044 name: brain microvascular endothelial cell def: "Any microvascular endothelial cell that is part of a brain." [GOC:TermGenie] is_a: CL:0002319 ! neural cell is_a: CL:2000008 ! microvascular endothelial cell is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:2000008 ! microvascular endothelial cell intersection_of: BFO:0000050 UBERON:0000955 ! part of brain relationship: BFO:0000050 UBERON:0000955 ! part of brain creation_date: 2014-07-09T00:24:53Z [Term] id: CL:2000046 name: ventricular cardiac muscle cell def: "Any cardiac muscle cell that is part of a cardiac ventricle." [GOC:TermGenie] is_a: CL:0000746 ! cardiac muscle cell intersection_of: CL:0000746 ! cardiac muscle cell intersection_of: BFO:0000050 UBERON:0002082 ! part of cardiac ventricle relationship: BFO:0000050 UBERON:0002082 ! part of cardiac ventricle creation_date: 2014-08-12T20:50:28Z [Term] id: CL:2000047 name: brainstem motor neuron def: "Any motor neuron that is part of a brainstem." [GOC:TermGenie] is_a: CL:0000100 ! motor neuron is_a: CL:2000029 ! central nervous system neuron intersection_of: CL:0000100 ! motor neuron intersection_of: RO:0002100 UBERON:0002298 ! has soma location brainstem relationship: RO:0002100 UBERON:0002298 ! has soma location brainstem relationship: RO:0002202 CL:0000031 ! develops from neuroblast (sensu Vertebrata) creation_date: 2014-10-02T23:52:53Z [Term] id: CL:2000051 name: splenic fibroblast def: "Any fibroblast that is part of a spleen." [GOC:TermGenie] is_a: CL:0000057 ! fibroblast is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000057 ! fibroblast intersection_of: BFO:0000050 UBERON:0002106 ! part of spleen relationship: BFO:0000050 UBERON:0002106 ! part of spleen creation_date: 2014-10-06T18:58:47Z [Term] id: CL:2000052 name: umbilical artery endothelial cell def: "Any endothelial cell of artery that is part of a umbilical cord." [GOC:TermGenie] is_a: CL:0000349 ! extraembryonic cell is_a: CL:1000413 ! endothelial cell of artery intersection_of: CL:1000413 ! endothelial cell of artery intersection_of: BFO:0000050 UBERON:0002331 ! part of umbilical cord relationship: BFO:0000050 UBERON:0002331 ! part of umbilical cord creation_date: 2014-10-06T19:01:48Z [Term] id: CL:2000053 name: splenic endothelial cell def: "Any endothelial cell that is part of a spleen." [GOC:TermGenie] is_a: CL:0000115 ! endothelial cell intersection_of: CL:0000115 ! endothelial cell intersection_of: BFO:0000050 UBERON:0002106 ! part of spleen relationship: BFO:0000050 UBERON:0002106 ! part of spleen creation_date: 2014-10-06T19:06:04Z [Term] id: CL:2000055 name: liver dendritic cell def: "Any dendritic cell that is part of a liver." [GOC:TermGenie] synonym: "hepatic dendritic cell" EXACT [] is_a: CL:0000451 ! dendritic cell is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: CL:0000451 ! dendritic cell intersection_of: BFO:0000050 UBERON:0002107 ! part of liver relationship: BFO:0000050 UBERON:0002107 ! part of liver creation_date: 2014-10-06T19:16:11Z [Term] id: CL:2000061 name: placental amniotic mesenchymal stromal cell def: "Any mesenchymal stem cell that is part of a placenta." [GOC:TermGenie] is_a: CL:0000134 ! mesenchymal stem cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000134 ! mesenchymal stem cell intersection_of: BFO:0000050 UBERON:0001987 ! part of placenta relationship: BFO:0000050 UBERON:0001987 ! part of placenta creation_date: 2014-10-07T17:51:11Z [Term] id: CL:2000063 name: ovarian fibroblast def: "Any fibroblast that is part of a female gonad." [GOC:TermGenie] is_a: CL:0000057 ! fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: BFO:0000050 UBERON:0000992 ! part of ovary relationship: BFO:0000050 UBERON:0000992 ! part of ovary creation_date: 2014-10-07T17:57:42Z [Term] id: CL:2000064 name: ovarian surface epithelial cell def: "Any epithelial cell that is part of a female gonad." [GOC:TermGenie] is_a: CL:0000066 ! epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: BFO:0000050 UBERON:0000992 ! part of ovary relationship: BFO:0000050 UBERON:0000992 ! part of ovary creation_date: 2014-10-07T17:59:13Z [Term] id: CL:2000065 name: ovarian microvascular endothelial cell def: "Any microvascular endothelial cell that is part of a female urethra." [GOC:TermGenie] is_a: CL:1000296 ! epithelial cell of urethra is_a: CL:2000008 ! microvascular endothelial cell intersection_of: CL:2000008 ! microvascular endothelial cell intersection_of: BFO:0000050 UBERON:0001334 ! part of female urethra relationship: BFO:0000050 UBERON:0001334 ! part of female urethra creation_date: 2014-10-07T18:18:01Z [Term] id: CL:2000066 name: cardiac ventricle fibroblast def: "Any fibroblast that is part of a cardiac ventricle." [GOC:TermGenie] is_a: CL:0002548 ! fibroblast of cardiac tissue intersection_of: CL:0000057 ! fibroblast intersection_of: BFO:0000050 UBERON:0002082 ! part of cardiac ventricle relationship: BFO:0000050 UBERON:0002082 ! part of cardiac ventricle creation_date: 2014-10-07T18:35:38Z [Term] id: CL:2000067 name: cardiac atrium fibroblast def: "Any fibroblast that is part of a cardiac atrium." [GOC:TermGenie] is_a: CL:0002548 ! fibroblast of cardiac tissue intersection_of: CL:0000057 ! fibroblast intersection_of: BFO:0000050 UBERON:0002081 ! part of cardiac atrium relationship: BFO:0000050 UBERON:0002081 ! part of cardiac atrium creation_date: 2014-10-07T18:36:54Z [Term] id: CL:2000068 name: pericardium fibroblast def: "Any fibroblast that is part of a pericardium." [GOC:TermGenie] is_a: CL:0000057 ! fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: BFO:0000050 UBERON:0002407 ! part of pericardium relationship: BFO:0000050 UBERON:0002407 ! part of pericardium creation_date: 2014-10-07T18:38:06Z [Term] id: CL:2000069 name: gallbladder fibroblast def: "Any fibroblast that is part of a gallbladder." [GOC:TermGenie] is_a: CL:0000057 ! fibroblast is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: CL:0000057 ! fibroblast intersection_of: BFO:0000050 UBERON:0002110 ! part of gallbladder relationship: BFO:0000050 UBERON:0002110 ! part of gallbladder creation_date: 2014-10-07T18:41:43Z [Term] id: CL:2000070 name: optic choroid fibroblast def: "Any fibroblast that is part of a optic choroid." [GOC:TermGenie] is_a: CL:0000057 ! fibroblast is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: CL:0000057 ! fibroblast intersection_of: BFO:0000050 UBERON:0001776 ! part of optic choroid relationship: BFO:0000050 UBERON:0001776 ! part of optic choroid creation_date: 2014-10-07T18:50:43Z [Term] id: CL:2000072 name: adipose microvascular endothelial cell def: "Any microvascular endothelial cell that is part of a adipose tissue." [GOC:TermGenie] is_a: CL:0002320 ! connective tissue cell is_a: CL:2000008 ! microvascular endothelial cell intersection_of: CL:2000008 ! microvascular endothelial cell intersection_of: BFO:0000050 UBERON:0001013 ! part of adipose tissue relationship: BFO:0000050 UBERON:0001013 ! part of adipose tissue creation_date: 2014-10-07T22:13:45Z [Term] id: CL:2000073 name: migratory cardiac neural crest cell def: "Any migratory neural crest cell that is part of a cardiac neural crest." [GOC:TermGenie] synonym: "cardiac neural crest cell" EXACT [PMID:33060096] is_a: CL:0000333 ! migratory neural crest cell intersection_of: CL:0000333 ! migratory neural crest cell intersection_of: BFO:0000050 UBERON:0000095 ! part of cardiac neural crest relationship: BFO:0000050 UBERON:0000095 ! part of cardiac neural crest creation_date: 2014-11-05T01:18:43Z [Term] id: CL:2000074 name: splenocyte def: "Any leukocyte that is part of a spleen." [GOC:TermGenie] is_a: CL:0000738 ! leukocyte is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000738 ! leukocyte intersection_of: BFO:0000050 UBERON:0002106 ! part of spleen relationship: BFO:0000050 UBERON:0002106 ! part of spleen creation_date: 2014-11-05T01:26:50Z [Term] id: CL:2000080 name: mesenchymal stem cell of abdominal adipose tissue def: "Any mesenchymal stem cell of adipose tissue that is part of an abdomen." [GOC:TermGenie] synonym: "mesenchymal stem cell of abdominal adipose" EXACT [] is_a: CL:0002570 ! mesenchymal stem cell of adipose tissue intersection_of: CL:0002570 ! mesenchymal stem cell of adipose tissue intersection_of: BFO:0000050 UBERON:0000916 ! part of abdomen relationship: BFO:0000050 UBERON:0000916 ! part of abdomen creation_date: 2014-12-02T19:10:34Z [Term] id: CL:2000085 name: mononuclear cell of umbilical cord def: "Any mononuclear cell that is part of a umbilical cord." [GOC:TermGenie] is_a: CL:0000349 ! extraembryonic cell is_a: CL:0000842 ! mononuclear cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000842 ! mononuclear cell intersection_of: BFO:0000050 UBERON:0002331 ! part of umbilical cord relationship: BFO:0000050 UBERON:0002331 ! part of umbilical cord creation_date: 2014-12-02T20:14:16Z [Term] id: CL:2000091 name: endometrial microvascular endothelial cell def: "Any microvascular endothelial cell that is part of a endometrial blood vessel." [GOC:TermGenie] is_a: CL:0009095 ! endothelial cell of uterus is_a: CL:2000008 ! microvascular endothelial cell intersection_of: CL:2000008 ! microvascular endothelial cell intersection_of: BFO:0000050 UBERON:0015172 ! part of endometrial blood vessel relationship: BFO:0000050 UBERON:0015172 ! part of endometrial blood vessel creation_date: 2015-03-31T21:02:36Z [Term] id: CL:2000095 name: cord blood hematopoietic stem cell def: "Any hematopoietic stem cell that is part of a umbilical cord blood." [GOC:TermGenie] is_a: CL:0002246 ! peripheral blood stem cell is_a: CL:0002352 ! gestational hematopoietic stem cell intersection_of: CL:0000037 ! hematopoietic stem cell intersection_of: BFO:0000050 UBERON:0012168 ! part of umbilical cord blood relationship: BFO:0000050 UBERON:0012168 ! part of umbilical cord blood creation_date: 2015-05-26T18:58:34Z [Term] id: CL:3000000 name: ciliated epithelial cell of esophagus def: "A ciliated epithelial cell of the esophagus." [GOC:CellBLAST, PMID:29802404] is_a: CL:0000067 ! ciliated epithelial cell is_a: CL:0002252 ! epithelial cell of esophagus intersection_of: CL:0000067 ! ciliated epithelial cell intersection_of: BFO:0000050 UBERON:0001976 ! part of epithelium of esophagus relationship: BFO:0000050 UBERON:0001976 ! part of epithelium of esophagus creation_date: 2019-02-09T16:40:30Z [Term] id: CL:3000004 name: peripheral sensory neuron def: "Peripheral sensory neuron." [GOC:CellBLAST, PMID:30096314] is_a: CL:0000101 ! sensory neuron is_a: CL:2000032 ! peripheral nervous system neuron intersection_of: CL:2000032 ! peripheral nervous system neuron intersection_of: RO:0002215 GO:0050906 ! capable of detection of stimulus involved in sensory perception creation_date: 2019-02-25T19:34:33Z [Term] id: CL:4023072 name: brain vascular cell def: "A cell that is part of the brain vasculature." [DOI:10.1101/2022.10.12.511898] is_a: CL:0002319 ! neural cell is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:0000000 ! cell intersection_of: BFO:0000050 UBERON:0008998 ! part of vasculature of brain relationship: BFO:0000050 UBERON:0008998 ! part of vasculature of brain [Term] id: CL:4023079 name: midbrain-derived inhibitory neuron def: "A GABAergic inhibitory neuron that is derived from the midbrain." [DOI:10.1101/2022.10.12.511898] is_a: CL:0000540 ! neuron is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:0000540 ! neuron intersection_of: RO:0002202 UBERON:0001891 ! develops from midbrain relationship: RO:0002202 UBERON:0001891 ! develops from midbrain [Term] id: CL:4023168 name: somatosensory neuron def: "A neuron that is part of the somatic sensory system. Somatosensory neurons innervate the skin or integument to detect different types of thermal, chemical, and mechanical touch stimuli." [PMID:22865660] is_a: CL:0000540 ! neuron intersection_of: CL:0000540 ! neuron intersection_of: BFO:0000050 UBERON:0003942 ! part of somatosensory system relationship: BFO:0000050 UBERON:0003942 ! part of somatosensory system [Term] id: CL:4028001 name: pulmonary capillary endothelial cell def: "Any capillary endothelial cell that is part of a lung." [] synonym: "lung capillary endothelial cell" EXACT [] is_a: CL:0002144 ! capillary endothelial cell is_a: CL:2000016 ! lung microvascular endothelial cell intersection_of: CL:0002144 ! capillary endothelial cell intersection_of: BFO:0000050 UBERON:0002048 ! part of lung relationship: BFO:0000050 UBERON:0016405 ! part of pulmonary capillary creation_date: 2021-11-23T02:31:40Z [Term] id: CL:4030025 name: renal cortical fibroblast def: "A fibroblast that is located in the renal cortical interstitium." [PMID:10559635] synonym: "kidney cortical fibroblast" EXACT [] is_a: CL:1000681 ! kidney cortex interstitial cell is_a: CL:1000692 ! kidney interstitial fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: BFO:0000050 UBERON:0005270 ! part of renal cortex interstitium [Term] id: CL:4030029 name: blood lymphocyte def: "A lymphocyte located in blood." [https://orcid.org/0000-0001-9990-8331] is_a: CL:0000542 ! lymphocyte is_a: CL:2000001 ! peripheral blood mononuclear cell intersection_of: CL:0000542 ! lymphocyte intersection_of: BFO:0000050 UBERON:0000178 ! part of blood [Term] id: CL:4030031 name: interstitial cell def: "Any cell that is located within the interstitium between the cells most prominent in defining a given tissue. \"Interstitial cell\" is a morphological term and refers to a variety of cells with differing origins and phenotypes." [PMID:24987007] is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: BFO:0000050 UBERON:0005169 ! part of interstitial tissue relationship: BFO:0000050 UBERON:0005169 ! part of interstitial tissue [Term] id: CL:4030034 name: respiratory ciliated cell def: "A ciliated cell of the respiratory system. Ciliated cells are present in airway epithelium." [PMID:18757316, PMID:21364219] synonym: "ciliated cell of the respiratory tract" EXACT [] is_a: CL:0000064 ! ciliated cell is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: CL:0000064 ! ciliated cell intersection_of: BFO:0000050 UBERON:0004802 ! part of respiratory tract epithelium relationship: BFO:0000050 UBERON:0004802 ! part of respiratory tract epithelium [Term] id: CL:4030040 name: endometrial ciliated epithelial cell def: "A ciliated cell of the endometrial epithelium. The cilia of this cell type help move mucus from glandular tissue of the endometrium." [doi:10.1038/s41591-020-1040-z, https://www.proteinatlas.org/humanproteome/single+cell+type/Glandular+epithelial+cells#endometrialciliatedcells] synonym: "ciliated cell of the endometrium" EXACT [] synonym: "endometrium ciliated epithelial cell" EXACT [] is_a: CL:0000067 ! ciliated epithelial cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000064 ! ciliated cell intersection_of: CL:0000066 ! epithelial cell intersection_of: BFO:0000050 UBERON:0004811 ! part of endometrium epithelium relationship: BFO:0000050 UBERON:0004811 ! part of endometrium epithelium [Term] id: CL:4030066 name: ureteric bud cell def: "An epithelial cell that is part of a ureteric bud. A ureteric bud cell has the potential to induce metanephric mesenchymal cells to proliferate and convert to epithelia that form renal tubules via: (1) the secretion of multiple diffusible growth factors that rescue renal progenitors from apoptosis and stimulate them to proliferate and (2) contact-dependent mechanisms that induce mesenchymal-epithelial conversion." [PMID:17133361, PMID:24183650, PMID:9374839] is_a: CL:0000068 ! duct epithelial cell is_a: CL:0002518 ! kidney epithelial cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000066 ! epithelial cell intersection_of: BFO:0000050 UBERON:0000084 ! part of ureteric bud relationship: BFO:0000050 UBERON:0000084 ! part of ureteric bud relationship: RO:0000056 GO:2001013 {xref="PMID:9374839"} ! participates in epithelial cell proliferation involved in renal tubule morphogenesis [Term] id: CL:4033008 name: vein endothelial cell of respiratory system def: "A(n) vein endothelial cell that is part of a(n) respiratory system." [PMID:34030460] is_a: CL:0002543 ! vein endothelial cell intersection_of: CL:0002543 ! vein endothelial cell intersection_of: BFO:0000050 UBERON:0001004 ! part of respiratory system relationship: BFO:0000050 UBERON:0001004 ! part of respiratory system [Term] id: CL:4033018 name: lung megakaryocyte def: "A megakaryocyte that is resident in the lung connective tissue." [PMID:33351116] synonym: "lung resident megakaryocyte" EXACT [PMID:36524131] synonym: "lung-resident megakaryocyte" EXACT [PMID:36524131] is_a: CL:0000556 ! megakaryocyte is_a: CL:0002320 ! connective tissue cell is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure intersection_of: CL:0000556 ! megakaryocyte intersection_of: BFO:0000050 UBERON:0000114 ! part of lung connective tissue relationship: BFO:0000050 UBERON:0000114 ! part of lung connective tissue [Term] id: CL:4033050 name: catecholaminergic neuron def: "A neuron that releases catecholamine as a neurotransmitter." [ISBN:0521442516, PMID:12094209] is_a: CL:0000151 ! secretory cell is_a: CL:0000540 ! neuron intersection_of: CL:0000540 ! neuron intersection_of: RO:0002215 GO:0160043 ! capable of catecholamine secretion, neurotransmission relationship: RO:0002215 GO:0160043 ! capable of catecholamine secretion, neurotransmission [Term] id: CL:4033054 name: perivascular cell def: "A cell that is adjacent to a vessel. A perivascular cell plays a crucial role in maintaining vascular function and tissue homeostasis. This cell type regulates vessel integrity and flow dynamics." [PMID:24928499, PMID:27889329] is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: RO:0002220 UBERON:0002049 ! adjacent to vasculature relationship: RO:0002220 UBERON:0002049 ! adjacent to vasculature [Term] id: CL:4033061 name: endothelial cell of central vein of liver def: "An endothelial cell that is part of a central vein of liver." [PMID:28287163] is_a: CL:0000115 ! endothelial cell is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure intersection_of: CL:0000115 ! endothelial cell intersection_of: BFO:0000050 UBERON:0006841 ! part of central vein of liver relationship: BFO:0000050 UBERON:0006841 ! part of central vein of liver [Term] id: CL:4040004 name: mesenchymal stem cell of orbital adipose tissue def: "Any mesenchymal stem cell of adipose tissue that is part of an orbital region." [https://orcid.org/0000-0002-0819-0473] synonym: "OAMSC" EXACT [PMID:31377878] synonym: "orbital adipose-derived mesenchymal stem cell" EXACT [PMID:31377878] synonym: "Orbital ASCs" EXACT [PMID:30210548] is_a: CL:0002570 ! mesenchymal stem cell of adipose tissue intersection_of: CL:0002570 ! mesenchymal stem cell of adipose tissue intersection_of: BFO:0000050 UBERON:0004088 ! part of orbital region relationship: BFO:0000050 UBERON:0004088 ! part of orbital region [Term] id: COB:0000013 name: molecule namespace: protein def: "A material entity that consists of two or more atoms that are all connected via covalent bonds such that any atom can be transitively connected with any other atom." [] [Term] id: COB:0000022 name: organism namespace: protein def: "A material entity that is a maximal functionally integrated unit that develops from a program encoded in a genome" [] is_a: UBERON:0000465 ! material anatomical entity [Term] id: GO:0000003 name: reproduction namespace: biological_process def: "The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms." [GOC:go_curators, GOC:isa_complete, GOC:jl, ISBN:0198506732] synonym: "reproductive physiological process" EXACT [] xref: Wikipedia:Reproduction is_a: GO:0008150 ! biological_process [Term] id: GO:0000011 name: vacuole inheritance namespace: biological_process def: "The distribution of vacuoles into daughter cells after mitosis or meiosis, mediated by interactions between vacuoles and the cytoskeleton." [GOC:mcc, PMID:10873824, PMID:14616069] is_a: GO:0007033 ! vacuole organization is_a: GO:0048308 ! organelle inheritance intersection_of: GO:0048308 ! organelle inheritance intersection_of: GOREL:0002003 GO:0005773 ! results in distribution of vacuole relationship: GOREL:0002003 GO:0005773 ! results in distribution of vacuole [Term] id: GO:0000070 name: mitotic sister chromatid segregation namespace: biological_process def: "The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets." [GOC:ai, GOC:jl] synonym: "mitotic chromosome segregation" EXACT [] is_a: GO:0000819 ! sister chromatid segregation is_a: GO:1903047 ! mitotic cell cycle process intersection_of: GO:0098813 ! nuclear chromosome segregation intersection_of: BFO:0000050 GO:0140014 ! part of mitotic nuclear division relationship: BFO:0000050 GO:0140014 ! part of mitotic nuclear division [Term] id: GO:0000139 name: Golgi membrane namespace: cellular_component def: "The lipid bilayer surrounding any of the compartments of the Golgi apparatus." [GOC:mah] synonym: "Golgi apparatus membrane" EXACT [] is_a: GO:0098588 ! bounding membrane of organelle intersection_of: GO:0016020 ! membrane intersection_of: RO:0002007 GO:0005794 ! bounding layer of Golgi apparatus relationship: RO:0002007 GO:0005794 ! bounding layer of Golgi apparatus [Term] id: GO:0000226 name: microtubule cytoskeleton organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins." [GOC:mah] synonym: "microtubule cytoskeleton organisation" EXACT [GOC:mah] is_a: GO:0007010 ! cytoskeleton organization is_a: GO:0007017 ! microtubule-based process intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0015630 ! results in organization of microtubule cytoskeleton relationship: RO:0002592 GO:0015630 ! results in organization of microtubule cytoskeleton [Term] id: GO:0000228 name: nuclear chromosome namespace: cellular_component def: "A chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact." [GOC:dph, GOC:mah] is_a: GO:0005694 ! chromosome intersection_of: GO:0005694 ! chromosome intersection_of: BFO:0000050 GO:0005634 ! part of nucleus relationship: BFO:0000050 GO:0031981 ! part of nuclear lumen [Term] id: GO:0000271 name: polysaccharide biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." [GOC:go_curators] synonym: "glycan biosynthesis" EXACT [] synonym: "glycan biosynthetic process" EXACT [] synonym: "polysaccharide anabolism" EXACT [] synonym: "polysaccharide biosynthesis" EXACT [] synonym: "polysaccharide formation" EXACT [] synonym: "polysaccharide synthesis" EXACT [] is_a: GO:0005976 ! polysaccharide metabolic process is_a: GO:0009059 ! macromolecule biosynthetic process is_a: GO:0016051 ! carbohydrate biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:18154 ! has primary output polysaccharide relationship: RO:0004008 CHEBI:18154 ! has primary output polysaccharide [Term] id: GO:0000272 name: polysaccharide catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." [PMID:33139480] synonym: "polysaccharide breakdown" EXACT [] synonym: "polysaccharide catabolism" EXACT [] synonym: "polysaccharide degradation" EXACT [] is_a: GO:0005976 ! polysaccharide metabolic process is_a: GO:0009057 ! macromolecule catabolic process is_a: GO:0016052 ! carbohydrate catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:18154 ! has primary input polysaccharide relationship: RO:0004009 CHEBI:18154 ! has primary input polysaccharide [Term] id: GO:0000278 name: mitotic cell cycle namespace: biological_process def: "Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent." [GOC:mah, ISBN:0815316194, Reactome:69278] xref: Wikipedia:Mitosis is_a: GO:0007049 ! cell cycle intersection_of: GO:0007049 ! cell cycle intersection_of: BFO:0000051 GO:0140014 ! has part mitotic nuclear division relationship: BFO:0000051 GO:0140014 ! has part mitotic nuclear division relationship: RO:0002160 NCBITaxon:2759 ! only in taxon Eukaryota relationship: RO:0002162 NCBITaxon:2759 {all_only="true"} ! in taxon Eukaryota [Term] id: GO:0000280 name: nuclear division namespace: biological_process def: "The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei." [GOC:mah] is_a: GO:0048285 ! organelle fission intersection_of: GO:0048285 ! organelle fission intersection_of: GOREL:0002004 GO:0005634 ! results in fission of nucleus relationship: GOREL:0002004 GO:0005634 ! results in fission of nucleus [Term] id: GO:0000313 name: organellar ribosome namespace: cellular_component def: "A ribosome contained within a subcellular membrane-bounded organelle." [GOC:mah, GOC:mcc] is_a: GO:0005840 ! ribosome intersection_of: GO:0005840 ! ribosome intersection_of: BFO:0000050 GO:0043226 ! part of organelle relationship: BFO:0000050 GO:0043226 ! part of organelle [Term] id: GO:0000578 name: embryonic axis specification namespace: biological_process def: "The establishment, maintenance and elaboration of a pattern along a line or a point in an embryo." [GOC:dph, GOC:go_curators, GOC:sdb_2009, GOC:tb] is_a: GO:0009798 ! axis specification is_a: GO:0009880 ! embryonic pattern specification [Term] id: GO:0000740 name: nuclear membrane fusion namespace: biological_process def: "The joining of 2 or more lipid bilayer membranes that surround the nucleus." [GOC:elh] is_a: GO:0071763 ! nuclear membrane organization is_a: GO:0090174 ! organelle membrane fusion intersection_of: GO:0061025 ! membrane fusion intersection_of: RO:0012008 GO:0031965 ! results in fusion of nuclear membrane relationship: RO:0012008 GO:0031965 ! results in fusion of nuclear membrane [Term] id: GO:0000741 name: karyogamy namespace: biological_process def: "The creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei." [GOC:elh] synonym: "nuclear fusion" EXACT [] synonym: "nuclear fusion during karyogamy" EXACT [] xref: Wikipedia:Karyogamy is_a: GO:0006997 ! nucleus organization is_a: GO:0048284 ! organelle fusion intersection_of: GO:0048284 ! organelle fusion intersection_of: RO:0012008 GO:0005634 ! results in fusion of nucleus relationship: BFO:0000050 GO:0006997 ! part of nucleus organization relationship: RO:0012008 GO:0005634 ! results in fusion of nucleus [Term] id: GO:0000768 name: syncytium formation by plasma membrane fusion namespace: biological_process def: "The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." [GOC:mtg_muscle, GOC:tb] is_a: GO:0006949 ! syncytium formation is_a: GO:0140253 ! cell-cell fusion intersection_of: GO:0006949 ! syncytium formation intersection_of: BFO:0000051 GO:0045026 ! has part plasma membrane fusion [Term] id: GO:0000785 name: chromatin namespace: cellular_component def: "The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome." [GOC:elh, PMID:20404130] xref: NIF_Subcellular:sao1615953555 is_a: GO:0032993 ! protein-DNA complex relationship: BFO:0000050 GO:0005694 ! part of chromosome [Term] id: GO:0000792 name: heterochromatin namespace: cellular_component def: "A compact and highly condensed form of chromatin that is refractory to transcription." [PMID:32017156] synonym: "transcriptionally inactive chromatin" EXACT [] synonym: "transcriptionally silent chromatin" EXACT [] xref: NIF_Subcellular:sao581845896 xref: Wikipedia:Heterochromatin is_a: GO:0000785 ! chromatin [Term] id: GO:0000819 name: sister chromatid segregation namespace: biological_process def: "The cell cycle process in which sister chromatids are organized and then physically separated and apportioned to two or more sets." [GOC:ai, GOC:elh] is_a: GO:0051276 ! chromosome organization is_a: GO:0098813 ! nuclear chromosome segregation [Term] id: GO:0000902 name: cell morphogenesis namespace: biological_process def: "The developmental process in which the size or shape of a cell is generated and organized." [GOC:clt, GOC:dph, GOC:go_curators, GOC:tb] synonym: "cellular morphogenesis" EXACT [] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 CL:0000000 ! results in morphogenesis of cell relationship: RO:0002298 CL:0000000 ! results in morphogenesis of cell [Term] id: GO:0001101 name: response to acid chemical namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form." [GOC:go_curators, GOC:rn] is_a: GO:0042221 ! response to chemical [Term] id: GO:0001501 name: skeletal system development namespace: biological_process def: "The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton)." [GOC:dph, GOC:jid, GOC:tb] synonym: "skeletal development" EXACT [] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001434 ! results in development of skeletal system relationship: RO:0002296 UBERON:0001434 ! results in development of skeletal system [Term] id: GO:0001503 name: ossification namespace: biological_process def: "The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance." [GOC:mtg_mpo, PMID:17572649] synonym: "bone biosynthesis" EXACT [] synonym: "bone formation" EXACT [] synonym: "osteogenesis" EXACT [] xref: Wikipedia:Ossification is_a: GO:0032501 ! multicellular organismal process intersection_of: GO:0032501 ! multicellular organismal process intersection_of: RO:0002297 UBERON:0001474 ! results in formation of anatomical entity bone element relationship: RO:0002297 UBERON:0001474 ! results in formation of anatomical entity bone element [Term] id: GO:0001508 name: action potential namespace: biological_process def: "A process in which membrane potential cycles through a depolarizing spike, triggered in response to depolarization above some threshold, followed by repolarization. This cycle is driven by the flow of ions through various voltage gated channels with different thresholds and ion specificities." [GOC:dph, GOC:go_curators, GOC:tb, ISBN:978-0-07-139011-8] is_a: GO:0042391 ! regulation of membrane potential [Term] id: GO:0001525 name: angiogenesis namespace: biological_process def: "Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels." [ISBN:0878932453] xref: Wikipedia:Angiogenesis is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0001981 ! results in formation of anatomical entity blood vessel relationship: BFO:0000050 GO:0048514 ! part of blood vessel morphogenesis relationship: RO:0002297 UBERON:0001981 ! results in formation of anatomical entity blood vessel [Term] id: GO:0001539 name: cilium or flagellum-dependent cell motility namespace: biological_process def: "Cell motility due to movement of eukaryotic cilia or bacterial-type flagella or archaeal-type flagella." [GOC:cilia, GOC:hjd, GOC:krc] synonym: "ciliary/flagellar motility" EXACT [] is_a: GO:0048870 ! cell motility [Term] id: GO:0001553 name: luteinization namespace: biological_process def: "The set of processes resulting in differentiation of theca and granulosa cells into luteal cells and in the formation of a corpus luteum after ovulation." [https://www.ncbi.nlm.nih.gov/books/NBK279054/] xref: Wikipedia:Luteal_phase xref: Wikipedia:Luteinization is_a: GO:0022602 ! ovulation cycle process relationship: BFO:0000050 GO:0008585 ! part of female gonad development [Term] id: GO:0001555 name: oocyte growth namespace: biological_process def: "The developmental growth process in which an oocyte irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present." [https://www.ncbi.nlm.nih.gov/books/NBK279054/] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0048588 ! developmental cell growth intersection_of: GO:0040007 ! growth intersection_of: RO:0002343 CL:0000023 ! results in growth of oocyte relationship: BFO:0000050 GO:0048599 ! part of oocyte development relationship: RO:0002160 NCBITaxon:33208 ! only in taxon Metazoa relationship: RO:0002162 NCBITaxon:33208 {all_only="true"} ! in taxon Metazoa relationship: RO:0002343 CL:0000023 ! results in growth of oocyte [Term] id: GO:0001556 name: oocyte maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for an oocyte to attain its fully functional state. Oocyte maturation commences after reinitiation of meiosis commonly starting with germinal vesicle breakdown, and continues up to the second meiotic arrest prior to fertilization." [GOC:devbiol, https://www.ncbi.nlm.nih.gov/books/NBK279054/] xref: Wikipedia:Oocyte_maturation is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0048469 ! cell maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 CL:0000023 ! results in maturation of oocyte relationship: BFO:0000050 GO:0048599 ! part of oocyte development relationship: RO:0002160 NCBITaxon:33208 ! only in taxon Metazoa relationship: RO:0002162 NCBITaxon:33208 {all_only="true"} ! in taxon Metazoa relationship: RO:0002299 CL:0000023 ! results in maturation of oocyte [Term] id: GO:0001558 name: regulation of cell growth namespace: biological_process def: "Any process that modulates the frequency, rate, extent or direction of cell growth." [GOC:go_curators] is_a: GO:0040008 ! regulation of growth is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0016049 ! regulates (processual) cell growth relationship: RO:0002211 GO:0016049 ! regulates (processual) cell growth [Term] id: GO:0001568 name: blood vessel development namespace: biological_process def: "The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood." [GOC:hjd, UBERON:0001981] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001981 ! results in development of blood vessel relationship: BFO:0000050 GO:0001944 ! part of vasculature development relationship: RO:0002296 UBERON:0001981 ! results in development of blood vessel [Term] id: GO:0001569 name: branching involved in blood vessel morphogenesis namespace: biological_process def: "The process of coordinated growth and sprouting of blood vessels giving rise to the organized vascular system." [GOC:dph] is_a: GO:0048754 ! branching morphogenesis of an epithelial tube intersection_of: GO:0048754 ! branching morphogenesis of an epithelial tube intersection_of: BFO:0000050 GO:0048514 ! part of blood vessel morphogenesis relationship: BFO:0000050 GO:0001525 ! part of angiogenesis [Term] id: GO:0001570 name: vasculogenesis namespace: biological_process def: "The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes." [PMID:8999798] synonym: "vascular morphogenesis" EXACT [] xref: Wikipedia:Vasculogenesis is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002297 UBERON:0001981 ! results in formation of anatomical entity blood vessel relationship: BFO:0000050 GO:0048514 ! part of blood vessel morphogenesis relationship: RO:0002297 UBERON:0001981 ! results in formation of anatomical entity blood vessel [Term] id: GO:0001578 name: microtubule bundle formation namespace: biological_process def: "A process that results in a parallel arrangement of microtubules." [GOC:dph] synonym: "microtubule bundling" EXACT [] is_a: GO:0000226 ! microtubule cytoskeleton organization relationship: RO:0000057 GO:0005874 ! has participant microtubule relationship: RO:0002297 GO:0097427 ! results in formation of anatomical entity microtubule bundle [Term] id: GO:0001654 name: eye development namespace: biological_process def: "The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight." [GOC:jid, GOC:jl] xref: Wikipedia:Eye_development is_a: GO:0007423 ! sensory organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000970 ! results in development of eye relationship: BFO:0000050 GO:0150063 ! part of visual system development relationship: RO:0002296 UBERON:0000970 ! results in development of eye [Term] id: GO:0001655 name: urogenital system development namespace: biological_process def: "The process whose specific outcome is the progression of the urogenital system over time, from its formation to the mature structure." [GOC:go_curators] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004122 ! results in development of genitourinary system relationship: BFO:0000051 GO:0072001 ! has part renal system development relationship: RO:0002296 UBERON:0004122 ! results in development of genitourinary system [Term] id: GO:0001656 name: metanephros development namespace: biological_process def: "The process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. In mammals, the metanephros is the excretory organ of the fetus, which develops into the mature kidney and is formed from the rear portion of the nephrogenic cord. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:bf, ISBN:0192800752] is_a: GO:0001822 ! kidney development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000081 ! results in development of metanephros relationship: RO:0002296 UBERON:0000081 ! results in development of metanephros [Term] id: GO:0001657 name: ureteric bud development namespace: biological_process def: "The process whose specific outcome is the progression of the ureteric bud over time, from its formation to the mature structure." [GOC:go_curators] is_a: GO:0072164 ! mesonephric tubule development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000084 ! results in development of ureteric bud relationship: RO:0002296 UBERON:0000084 ! results in development of ureteric bud [Term] id: GO:0001658 name: branching involved in ureteric bud morphogenesis namespace: biological_process def: "The process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules." [GOC:dph, PMID:16916378] synonym: "ureteric bud branching" EXACT [GOC:dph] is_a: GO:0048754 ! branching morphogenesis of an epithelial tube intersection_of: GO:0001763 ! morphogenesis of a branching structure intersection_of: BFO:0000050 GO:0060675 ! part of ureteric bud morphogenesis relationship: BFO:0000050 GO:0060675 ! part of ureteric bud morphogenesis [Term] id: GO:0001659 name: temperature homeostasis namespace: biological_process def: "A homeostatic process in which an organism modulates its internal body temperature." [GOC:jl] synonym: "thermoregulation" EXACT [GOC:dph, GOC:tb] xref: Wikipedia:Thermoregulation is_a: GO:0048871 ! multicellular organismal-level homeostasis [Term] id: GO:0001666 name: response to hypoxia namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level." [GOC:hjd] synonym: "response to hypoxic stress" EXACT [] synonym: "response to lowered oxygen tension" EXACT [] is_a: GO:0006950 ! response to stress is_a: GO:0036293 ! response to decreased oxygen levels [Term] id: GO:0001667 name: ameboidal-type cell migration namespace: biological_process def: "Cell migration that is accomplished by extension and retraction of a pseudopodium." [GOC:dph] synonym: "ameboid cell migration" EXACT [] synonym: "amoeboid cell migration" EXACT [] synonym: "amoeboidal cell migration" EXACT [] is_a: GO:0016477 ! cell migration [Term] id: GO:0001669 name: acrosomal vesicle namespace: cellular_component def: "A structure in the head of a spermatozoon that contains acid hydrolases, and is concerned with the breakdown of the outer membrane of the ovum during fertilization. It lies just beneath the plasma membrane and is derived from the lysosome." [ISBN:0124325653, ISBN:0198506732] synonym: "acrosomal granule" EXACT [GOC:sart] synonym: "acrosome" EXACT [GOC:dph] xref: Wikipedia:Acrosome is_a: GO:0030141 ! secretory granule relationship: BFO:0000050 CL:0000019 ! part of sperm [Term] id: GO:0001673 name: male germ cell nucleus namespace: cellular_component def: "The nucleus of a male germ cell, a reproductive cell in males." [CL:0000015, GOC:hjd, GOC:mtg_sensu] synonym: "male germ-cell nucleus" EXACT [] is_a: GO:0043073 ! germ cell nucleus intersection_of: GO:0005634 ! nucleus intersection_of: BFO:0000050 CL:0000015 ! part of male germ cell relationship: BFO:0000050 CL:0000015 ! part of male germ cell relationship: RO:0002162 NCBITaxon:2759 {all_only="true"} ! in taxon Eukaryota [Term] id: GO:0001674 name: female germ cell nucleus namespace: cellular_component def: "The nucleus of the female germ cell, a reproductive cell in females." [CL:0000021, GOC:hjd] synonym: "female germ-cell nucleus" EXACT [] is_a: GO:0043073 ! germ cell nucleus intersection_of: GO:0005634 ! nucleus intersection_of: BFO:0000050 CL:0000021 ! part of female germ cell relationship: BFO:0000050 CL:0000021 ! part of female germ cell relationship: RO:0002162 NCBITaxon:2759 {all_only="true"} ! in taxon Eukaryota [Term] id: GO:0001675 name: acrosome assembly namespace: biological_process def: "The formation of the acrosome from the spermatid Golgi." [GOC:dph, GOC:hjd, GOC:tb] synonym: "acrosome formation" EXACT [GOC:dph, GOC:tb] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0010927 ! cellular component assembly involved in morphogenesis is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0033363 ! secretory granule organization is_a: GO:0070925 ! organelle assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0001669 ! results in assembly of acrosomal vesicle relationship: BFO:0000050 GO:0007286 ! part of spermatid development relationship: RO:0002588 GO:0001669 ! results in assembly of acrosomal vesicle [Term] id: GO:0001677 name: formation of translation initiation ternary complex namespace: biological_process def: "Formation of a complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator)." [GOC:hjd] synonym: "translation initiation ternary complex assembly" EXACT [] is_a: GO:0022618 ! protein-RNA complex assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0044207 ! results in assembly of translation initiation ternary complex relationship: BFO:0000050 GO:0006413 ! part of translational initiation relationship: RO:0002588 GO:0044207 ! results in assembly of translation initiation ternary complex [Term] id: GO:0001696 name: gastric acid secretion namespace: biological_process def: "The regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion." [GOC:hjd] is_a: GO:0022600 ! digestive system process is_a: GO:0046717 ! acid secretion [Term] id: GO:0001700 name: embryonic development via the syncytial blastoderm namespace: biological_process def: "The process whose specific outcome is the progression of the embryo over time, from zygote formation through syncytial blastoderm to the hatching of the first instar larva. An example of this process is found in Drosophila melanogaster." [GOC:go_curators, GOC:mtg_sensu] is_a: GO:0009792 ! embryo development ending in birth or egg hatching relationship: RO:0002160 NCBITaxon:50557 ! only in taxon Insecta relationship: RO:0002162 NCBITaxon:50557 {all_only="true"} ! in taxon Insecta [Term] id: GO:0001701 name: in utero embryonic development namespace: biological_process def: "The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus." [GOC:go_curators, GOC:mtg_sensu] is_a: GO:0043009 ! chordate embryonic development relationship: RO:0002160 NCBITaxon:32525 ! only in taxon Theria relationship: RO:0002162 NCBITaxon:32525 {all_only="true"} ! in taxon Theria [Term] id: GO:0001702 name: gastrulation with mouth forming second namespace: biological_process def: "A gastrulation process in which the initial invagination becomes the anus and the mouth forms second." [GOC:go_curators, GOC:mtg_sensu] synonym: "deuterostomic gastrulation" EXACT [GOC:dph] is_a: GO:0007369 ! gastrulation relationship: RO:0002160 NCBITaxon:33511 ! only in taxon Deuterostomia relationship: RO:0002162 NCBITaxon:33511 {all_only="true"} ! in taxon Deuterostomia [Term] id: GO:0001704 name: formation of primary germ layer namespace: biological_process def: "The formation of the ectoderm, mesoderm and endoderm during gastrulation." [GOC:go_curators] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0000923 ! results in formation of anatomical entity germ layer relationship: BFO:0000050 GO:0007369 ! part of gastrulation relationship: RO:0002297 UBERON:0000923 ! results in formation of anatomical entity germ layer [Term] id: GO:0001705 name: ectoderm formation namespace: biological_process def: "The formation of ectoderm during gastrulation." [GOC:go_curators] is_a: GO:0001704 ! formation of primary germ layer intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0000924 ! results in formation of anatomical entity ectoderm relationship: BFO:0000050 GO:0007398 ! part of ectoderm development relationship: RO:0002297 UBERON:0000924 ! results in formation of anatomical entity ectoderm [Term] id: GO:0001706 name: endoderm formation namespace: biological_process def: "The formation of the endoderm during gastrulation." [GOC:go_curators] is_a: GO:0001704 ! formation of primary germ layer intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0000925 ! results in formation of anatomical entity endoderm relationship: BFO:0000050 GO:0007492 ! part of endoderm development relationship: RO:0002297 UBERON:0000925 ! results in formation of anatomical entity endoderm [Term] id: GO:0001707 name: mesoderm formation namespace: biological_process def: "The process that gives rise to the mesoderm. This process pertains to the initial formation of the structure from unspecified parts." [GOC:go_curators] is_a: GO:0001704 ! formation of primary germ layer intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0000926 ! results in formation of anatomical entity mesoderm relationship: BFO:0000050 GO:0048332 ! part of mesoderm morphogenesis relationship: RO:0002297 UBERON:0000926 ! results in formation of anatomical entity mesoderm [Term] id: GO:0001743 name: lens placode formation namespace: biological_process def: "The initial developmental process that will lead to the formation of an eye." [GOC:dph] is_a: GO:0060788 ! ectodermal placode formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0003073 ! results in formation of anatomical entity lens placode relationship: BFO:0000050 GO:0048598 ! part of embryonic morphogenesis relationship: RO:0002297 UBERON:0003073 ! results in formation of anatomical entity lens placode [Term] id: GO:0001745 name: compound eye morphogenesis namespace: biological_process def: "The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster." [GOC:dph, GOC:mtg_sensu] synonym: "insect-type retina morphogenesis" EXACT [PMID:11735386] is_a: GO:0048592 ! eye morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000018 ! results in morphogenesis of compound eye relationship: BFO:0000050 GO:0048749 ! part of compound eye development relationship: RO:0002160 NCBITaxon:6656 ! only in taxon Arthropoda relationship: RO:0002162 NCBITaxon:6656 {all_only="true"} ! in taxon Arthropoda relationship: RO:0002298 UBERON:0000018 ! results in morphogenesis of compound eye [Term] id: GO:0001751 name: compound eye photoreceptor cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized features of an eye photoreceptor cell." [GOC:go_curators] is_a: GO:0001754 ! eye photoreceptor cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:2000019 ! results in acquisition of features of compound eye photoreceptor cell relationship: BFO:0000050 GO:0001745 ! part of compound eye morphogenesis relationship: RO:0002315 CL:2000019 ! results in acquisition of features of compound eye photoreceptor cell [Term] id: GO:0001754 name: eye photoreceptor cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell, as found in the eye, the primary visual organ of most organisms." [GOC:go_curators] is_a: GO:0046530 ! photoreceptor cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000287 ! results in acquisition of features of eye photoreceptor cell relationship: BFO:0000050 GO:0048592 ! part of eye morphogenesis relationship: RO:0002315 CL:0000287 ! results in acquisition of features of eye photoreceptor cell [Term] id: GO:0001755 name: neural crest cell migration namespace: biological_process def: "The characteristic movement of cells from the dorsal ridge of the neural tube to a variety of locations in a vertebrate embryo." [GOC:ascb_2009, GOC:dph, GOC:tb, ISBN:0878932437] is_a: GO:0090497 ! mesenchymal cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000333 ! results in movement of migratory neural crest cell relationship: BFO:0000050 GO:0014032 ! part of neural crest cell development relationship: RO:0002565 CL:0000333 ! results in movement of migratory neural crest cell [Term] id: GO:0001756 name: somitogenesis namespace: biological_process def: "The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo." [ISBN:0721662544] xref: Wikipedia:Somitogenesis is_a: GO:0009952 ! anterior/posterior pattern specification is_a: GO:0035282 ! segmentation is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0002329 ! results in formation of anatomical entity somite relationship: BFO:0000050 GO:0043009 ! part of chordate embryonic development relationship: BFO:0000050 GO:0061053 ! part of somite development relationship: RO:0002297 UBERON:0002329 ! results in formation of anatomical entity somite [Term] id: GO:0001763 name: morphogenesis of a branching structure namespace: biological_process def: "The process in which the anatomical structures of branches are generated and organized. A branch is a division or offshoot from a main stem. Examples in animals would include blood vessels, nerves, lymphatics and other endothelial or epithelial tubes." [ISBN:0721662544] synonym: "branching morphogenesis" EXACT [GOC:dph] is_a: GO:0009653 ! anatomical structure morphogenesis is_a: GO:0032501 ! multicellular organismal process [Term] id: GO:0001764 name: neuron migration namespace: biological_process def: "The characteristic movement of an immature neuron from germinal zones to specific positions where they will reside as they mature." [CL:0000540, GOC:go_curators] synonym: "neuron chemotaxis" EXACT [] synonym: "neuronal migration" EXACT [] xref: Wikipedia:Neural_development#Neuron_migration xref: Wikipedia:Neuron_migration is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000540 ! results in movement of neuron relationship: BFO:0000050 GO:0048699 ! part of generation of neurons relationship: RO:0002565 CL:0000540 ! results in movement of neuron [Term] id: GO:0001767 name: establishment of lymphocyte polarity namespace: biological_process def: "The directed orientation of lymphocyte signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with an appropriate activating cell." [GOC:mgi_curators, PMID:11244041, PMID:12615889] synonym: "lymphocyte polarization" EXACT [] is_a: GO:0030010 ! establishment of cell polarity intersection_of: GO:0030010 ! establishment of cell polarity intersection_of: BFO:0000066 CL:0000542 ! occurs in lymphocyte relationship: BFO:0000050 GO:0046649 ! part of lymphocyte activation relationship: BFO:0000066 CL:0000542 ! occurs in lymphocyte [Term] id: GO:0001768 name: establishment of T cell polarity namespace: biological_process def: "The directed orientation of T cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with antigen presenting cell." [GOC:mgi_curators, PMID:11244041, PMID:12615889] synonym: "establishment of T lymphocyte polarity" EXACT [] synonym: "establishment of T-cell polarity" EXACT [] synonym: "establishment of T-lymphocyte polarity" EXACT [] synonym: "T cell polarization" EXACT [] synonym: "T lymphocyte polarization" EXACT [] synonym: "T-cell polarization" EXACT [] is_a: GO:0001767 ! establishment of lymphocyte polarity intersection_of: GO:0030010 ! establishment of cell polarity intersection_of: BFO:0000066 CL:0000084 ! occurs in T cell relationship: BFO:0000050 GO:0042110 ! part of T cell activation relationship: BFO:0000066 CL:0000084 ! occurs in T cell [Term] id: GO:0001775 name: cell activation namespace: biological_process def: "A multicellular organismal process by which exposure to an activating factor such as a cellular or soluble ligand results in a change in the morphology or behavior of a cell." [GOC:mgi_curators] is_a: GO:0009987 ! cellular process is_a: GO:0032501 ! multicellular organismal process relationship: RO:0002160 NCBITaxon:33208 ! only in taxon Metazoa relationship: RO:0002162 NCBITaxon:33208 {all_only="true"} ! in taxon Metazoa [Term] id: GO:0001776 name: leukocyte homeostasis namespace: biological_process def: "The process of regulating the proliferation and elimination of cells of the immune system such that the total number of cells of a particular cell type within a whole or part of an organism is stable over time in the absence of an outside stimulus." [GOC:add, ISBN:0781735149] synonym: "immune cell homeostasis" EXACT [] synonym: "leucocyte homeostasis" EXACT [] is_a: GO:0002376 ! immune system process is_a: GO:0048872 ! homeostasis of number of cells intersection_of: GO:0048872 ! homeostasis of number of cells intersection_of: RO:0012003 CL:0000738 ! acts on population of leukocyte relationship: RO:0002160 NCBITaxon:7742 ! only in taxon Vertebrata relationship: RO:0002162 NCBITaxon:7742 {all_only="true"} ! in taxon Vertebrata relationship: RO:0012003 CL:0000738 ! acts on population of leukocyte [Term] id: GO:0001777 name: T cell homeostatic proliferation namespace: biological_process def: "The non-specific expansion of T cell populations within a whole or part of an organism to reach to a total number of T cells which will then remain stable over time in the absence of an external stimulus." [GOC:mgi_curators, ISBN:0781735149] synonym: "resting T cell proliferation" EXACT [] synonym: "resting T-cell proliferation" EXACT [] synonym: "T lymphocyte homeostatic proliferation" EXACT [] synonym: "T-cell homeostatic proliferation" EXACT [] synonym: "T-lymphocyte homeostatic proliferation" EXACT [] is_a: GO:0042098 ! T cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: BFO:0000050 GO:0042592 ! part of homeostatic process intersection_of: RO:0012003 CL:0000084 ! acts on population of T cell relationship: BFO:0000050 GO:0043029 ! part of T cell homeostasis [Term] id: GO:0001816 name: cytokine production namespace: biological_process def: "The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:add, ISBN:0781735149] is_a: GO:0010467 ! gene expression is_a: GO:0032501 ! multicellular organismal process [Term] id: GO:0001817 name: regulation of cytokine production namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of production of a cytokine." [GOC:add, ISBN:0781735149] synonym: "regulation of cytokine anabolism" EXACT [] synonym: "regulation of cytokine biosynthesis" EXACT [] synonym: "regulation of cytokine formation" EXACT [] synonym: "regulation of cytokine synthesis" EXACT [] is_a: GO:0010468 ! regulation of gene expression is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001816 ! regulates (processual) cytokine production relationship: RO:0002211 GO:0001816 ! regulates (processual) cytokine production [Term] id: GO:0001818 name: negative regulation of cytokine production namespace: biological_process def: "Any process that stops, prevents, or reduces the rate of production of a cytokine." [GOC:add, ISBN:0781735149] synonym: "down regulation of cytokine biosynthetic process" EXACT [] synonym: "down regulation of cytokine production" EXACT [] synonym: "down-regulation of cytokine biosynthetic process" EXACT [] synonym: "down-regulation of cytokine production" EXACT [] synonym: "downregulation of cytokine biosynthetic process" EXACT [] synonym: "downregulation of cytokine production" EXACT [] synonym: "negative regulation of cytokine anabolism" EXACT [] synonym: "negative regulation of cytokine biosynthesis" EXACT [] synonym: "negative regulation of cytokine formation" EXACT [] synonym: "negative regulation of cytokine synthesis" EXACT [] is_a: GO:0001817 ! regulation of cytokine production is_a: GO:0010629 ! negative regulation of gene expression is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001816 ! negatively regulates cytokine production relationship: RO:0002212 GO:0001816 ! negatively regulates cytokine production [Term] id: GO:0001819 name: positive regulation of cytokine production namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of production of a cytokine." [GOC:add, ISBN:0781735149] synonym: "up regulation of cytokine production" EXACT [] synonym: "up-regulation of cytokine production" EXACT [] synonym: "upregulation of cytokine production" EXACT [] is_a: GO:0001817 ! regulation of cytokine production is_a: GO:0010628 ! positive regulation of gene expression is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001816 ! positively regulates cytokine production relationship: RO:0002213 GO:0001816 ! positively regulates cytokine production [Term] id: GO:0001820 name: serotonin secretion namespace: biological_process def: "The regulated release of serotonin by a cell. Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine synthesised in serotonergic neurons in the central nervous system, enterochromaffin cells in the gastrointestinal tract and some immune system cells." [GOC:ef, ISBN:0198506732, ISBN:0781735149] synonym: "5-HT secretion" EXACT [] synonym: "5-hydroxytryptamine secretion" EXACT [] is_a: GO:0006837 ! serotonin transport is_a: GO:0023061 ! signal release intersection_of: GO:0046903 ! secretion intersection_of: RO:0004009 CHEBI:350546 ! has primary input serotonin(1+) [Term] id: GO:0001822 name: kidney development namespace: biological_process def: "The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine." [GOC:dph, GOC:mtg_kidney_jan10, ISBN:0124020607, ISBN:0721662544] xref: Wikipedia:Kidney_development is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002113 ! results in development of kidney relationship: BFO:0000050 GO:0072001 ! part of renal system development relationship: RO:0002296 UBERON:0002113 ! results in development of kidney [Term] id: GO:0001823 name: mesonephros development namespace: biological_process def: "The process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. In mammals, the mesonephros is the second of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the mesonephros will form the mature kidney." [GOC:dph, ISBN:0124020607, ISBN:0721662544, PMID:10535314] synonym: "Wolffian body development" EXACT [GOC:dph] is_a: GO:0001822 ! kidney development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000080 ! results in development of mesonephros relationship: RO:0002296 UBERON:0000080 ! results in development of mesonephros [Term] id: GO:0001824 name: blastocyst development namespace: biological_process def: "The process whose specific outcome is the progression of the blastocyst over time, from its formation to the mature structure. The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm." [GOC:dph, ISBN:0124020607, ISBN:0198542771] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000358 ! results in development of blastocyst relationship: BFO:0000050 GO:0001701 ! part of in utero embryonic development relationship: RO:0002160 NCBITaxon:32525 ! only in taxon Theria relationship: RO:0002162 NCBITaxon:32525 {all_only="true"} ! in taxon Theria relationship: RO:0002296 UBERON:0000358 ! results in development of blastocyst [Term] id: GO:0001825 name: blastocyst formation namespace: biological_process def: "The initial formation of a blastocyst from a solid ball of cells known as a morula." [GOC:dph, ISBN:0124020607, ISBN:0198542771] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0000358 ! results in formation of anatomical entity blastocyst relationship: BFO:0000050 GO:0001824 ! part of blastocyst development relationship: RO:0002297 UBERON:0000358 ! results in formation of anatomical entity blastocyst [Term] id: GO:0001826 name: inner cell mass cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of an inner cell mass cell." [GOC:dph, ISBN:0124020607, ISBN:0198542771] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:2000020 ! results in acquisition of features of inner cell mass cell relationship: BFO:0000050 GO:0001825 ! part of blastocyst formation relationship: RO:0002315 CL:2000020 ! results in acquisition of features of inner cell mass cell [Term] id: GO:0001829 name: trophectodermal cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized features of a trophectoderm cell." [GOC:dph, ISBN:0124020607, ISBN:0198542771] synonym: "trophectoderm cell differentiation" EXACT [] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:1000274 ! results in acquisition of features of trophectodermal cell relationship: BFO:0000050 GO:0001825 ! part of blastocyst formation relationship: RO:0002315 CL:1000274 ! results in acquisition of features of trophectodermal cell [Term] id: GO:0001831 name: trophectodermal cellular morphogenesis namespace: biological_process def: "The morphogenesis of trophectoderm cells." [GOC:dph, ISBN:0124020607, ISBN:0198542771] synonym: "trophectoderm cellular morphogenesis" EXACT [] is_a: GO:0000902 ! cell morphogenesis is_a: GO:0048598 ! embryonic morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 CL:1000274 ! results in morphogenesis of trophectodermal cell relationship: BFO:0000050 GO:0001829 ! part of trophectodermal cell differentiation relationship: RO:0002298 CL:1000274 ! results in morphogenesis of trophectodermal cell [Term] id: GO:0001832 name: blastocyst growth namespace: biological_process def: "An increase in size of a blastocyst due to expansion of the blastocoelic cavity cell shape changes and cell proliferation." [GOC:dph, ISBN:0124020607, ISBN:0198542771] is_a: GO:0048589 ! developmental growth intersection_of: GO:0040007 ! growth intersection_of: RO:0002343 UBERON:0000358 ! results in growth of blastocyst relationship: BFO:0000050 GO:0001824 ! part of blastocyst development relationship: RO:0002343 UBERON:0000358 ! results in growth of blastocyst [Term] id: GO:0001833 name: inner cell mass cell proliferation namespace: biological_process def: "The proliferation of cells in the inner cell mass." [GOC:dph, GOC:isa_complete, ISBN:0124020607, ISBN:0198542771] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:2000020 ! acts on population of inner cell mass cell relationship: BFO:0000050 GO:0001832 ! part of blastocyst growth relationship: RO:0012003 CL:2000020 ! acts on population of inner cell mass cell [Term] id: GO:0001834 name: trophectodermal cell proliferation namespace: biological_process def: "The proliferation of cells in the trophectoderm." [GOC:dph, ISBN:0124020607, ISBN:0198542771] synonym: "trophectoderm cell proliferation" EXACT [] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:1000274 ! acts on population of trophectodermal cell relationship: BFO:0000050 GO:0001832 ! part of blastocyst growth relationship: RO:0012003 CL:1000274 ! acts on population of trophectodermal cell [Term] id: GO:0001837 name: epithelial to mesenchymal transition namespace: biological_process def: "A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell." [GOC:dph, PMID:14701881] synonym: "EMT" EXACT [] synonym: "epithelial-mesenchymal transition" EXACT [] synonym: "mesenchymal cell differentiation from epithelial cell" EXACT [GOC:BHF, GOC:dph, GOC:rl] is_a: GO:0048762 ! mesenchymal cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0008019 ! results in acquisition of features of mesenchymal cell intersection_of: RO:0004009 CL:0000066 ! has primary input epithelial cell relationship: RO:0004009 CL:0000066 ! has primary input epithelial cell [Term] id: GO:0001838 name: embryonic epithelial tube formation namespace: biological_process def: "The morphogenesis of an embryonic epithelium into a tube-shaped structure." [GOC:dph, ISBN:0824072820] is_a: GO:0072175 ! epithelial tube formation relationship: BFO:0000050 GO:0016331 ! part of morphogenesis of embryonic epithelium [Term] id: GO:0001839 name: neural plate morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the neural plate are generated and organized. The neural plate is a specialized region of columnar epithelial cells in the dorsal ectoderm that will give rise to nervous system tissue." [GOC:dph, ISBN:0878932437] is_a: GO:0016331 ! morphogenesis of embryonic epithelium intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003075 ! results in morphogenesis of neural plate relationship: BFO:0000050 GO:0001840 ! part of neural plate development relationship: RO:0002298 UBERON:0003075 ! results in morphogenesis of neural plate [Term] id: GO:0001840 name: neural plate development namespace: biological_process def: "The process whose specific outcome is the progression of the neural plate over time, from its formation to the mature structure. The neural plate is a flat, thickened layer of ectodermal cells. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system." [GOC:dph, GOC:ef, ISBN:0878932437, ISBN:0878932585] is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003075 ! results in development of neural plate relationship: BFO:0000050 GO:0043009 ! part of chordate embryonic development relationship: RO:0002296 UBERON:0003075 ! results in development of neural plate [Term] id: GO:0001841 name: neural tube formation namespace: biological_process def: "The formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system." [GOC:dph, ISBN:0878932437] synonym: "neural tube morphogenesis" EXACT [GOC:dph] synonym: "neurulation" EXACT [] xref: Wikipedia:Neurulation is_a: GO:0001838 ! embryonic epithelial tube formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0001049 ! results in formation of anatomical entity neural tube relationship: BFO:0000050 GO:0021915 ! part of neural tube development relationship: RO:0002297 UBERON:0001049 ! results in formation of anatomical entity neural tube [Term] id: GO:0001842 name: neural fold formation namespace: biological_process def: "The process in which the neural fold is formed. The edges of the neural plate thicken and move up to form a U-shaped structure called the neural groove." [GOC:dph, ISBN:0878932437] is_a: GO:0016331 ! morphogenesis of embryonic epithelium is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis is_a: GO:0060571 ! morphogenesis of an epithelial fold intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0005062 ! results in formation of anatomical entity neural fold relationship: BFO:0000050 GO:0014020 ! part of primary neural tube formation relationship: RO:0002297 UBERON:0005062 ! results in formation of anatomical entity neural fold [Term] id: GO:0001878 name: response to yeast namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a yeast species." [PMID:14707091] is_a: GO:0009620 ! response to fungus intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 NCBITaxon:147537 ! has primary input Saccharomycotina relationship: RO:0004009 NCBITaxon:147537 ! has primary input Saccharomycotina [Term] id: GO:0001885 name: endothelial cell development namespace: biological_process def: "The progression of an endothelial cell over time, from its formation to the mature structure." [GOC:dph] is_a: GO:0002064 ! epithelial cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000115 ! results in development of endothelial cell relationship: BFO:0000050 GO:0045446 ! part of endothelial cell differentiation relationship: RO:0002296 CL:0000115 ! results in development of endothelial cell [Term] id: GO:0001886 name: endothelial cell morphogenesis namespace: biological_process def: "The change in form (cell shape and size) that occurs during the differentiation of an endothelial cell." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0003382 ! epithelial cell morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 CL:0000115 ! results in morphogenesis of endothelial cell relationship: BFO:0000050 GO:0001885 ! part of endothelial cell development relationship: RO:0002298 CL:0000115 ! results in morphogenesis of endothelial cell [Term] id: GO:0001889 name: liver development namespace: biological_process def: "The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes." [GOC:add, ISBN:068340007X] is_a: GO:0048732 ! gland development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002107 ! results in development of liver relationship: BFO:0000050 GO:0061008 ! part of hepaticobiliary system development relationship: RO:0002296 UBERON:0002107 ! results in development of liver [Term] id: GO:0001890 name: placenta development namespace: biological_process def: "The process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin." [GOC:add, ISBN:068340007X] synonym: "placental development" EXACT [] synonym: "placentation" EXACT [GOC:dph, GOC:tb] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001987 ! results in development of placenta relationship: RO:0002160 NCBITaxon:32525 ! only in taxon Theria relationship: RO:0002162 NCBITaxon:32525 {all_only="true"} ! in taxon Theria relationship: RO:0002296 UBERON:0001987 ! results in development of placenta [Term] id: GO:0001892 name: embryonic placenta development namespace: biological_process def: "The embryonically driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin." [GOC:add, ISBN:068340007X] synonym: "fetal placenta development" EXACT [GOC:dph] is_a: GO:0048568 ! embryonic organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0007106 ! results in development of chorionic villus relationship: BFO:0000050 GO:0001701 ! part of in utero embryonic development relationship: BFO:0000050 GO:0001890 ! part of placenta development relationship: RO:0002296 UBERON:0007106 ! results in development of chorionic villus [Term] id: GO:0001893 name: maternal placenta development namespace: biological_process def: "Maternally driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin." [GOC:add, ISBN:068340007X] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0048856 ! anatomical structure development is_a: GO:0060135 ! maternal process involved in female pregnancy intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002450 ! results in development of decidua relationship: BFO:0000050 GO:0001890 ! part of placenta development relationship: RO:0002296 UBERON:0002450 ! results in development of decidua [Term] id: GO:0001935 name: endothelial cell proliferation namespace: biological_process def: "The multiplication or reproduction of endothelial cells, resulting in the expansion of a cell population. Endothelial cells are thin flattened cells which line the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium." [GOC:add, ISBN:0781735149] is_a: GO:0050673 ! epithelial cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000115 ! acts on population of endothelial cell relationship: RO:0012003 CL:0000115 ! acts on population of endothelial cell [Term] id: GO:0001936 name: regulation of endothelial cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of endothelial cell proliferation." [GOC:add] is_a: GO:0050678 ! regulation of epithelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001935 ! regulates (processual) endothelial cell proliferation relationship: RO:0002211 GO:0001935 ! regulates (processual) endothelial cell proliferation [Term] id: GO:0001937 name: negative regulation of endothelial cell proliferation namespace: biological_process def: "Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation." [GOC:add] synonym: "down regulation of endothelial cell proliferation" EXACT [] synonym: "down-regulation of endothelial cell proliferation" EXACT [] synonym: "downregulation of endothelial cell proliferation" EXACT [] is_a: GO:0001936 ! regulation of endothelial cell proliferation is_a: GO:0050680 ! negative regulation of epithelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001935 ! negatively regulates endothelial cell proliferation relationship: RO:0002212 GO:0001935 ! negatively regulates endothelial cell proliferation [Term] id: GO:0001938 name: positive regulation of endothelial cell proliferation namespace: biological_process def: "Any process that activates or increases the rate or extent of endothelial cell proliferation." [GOC:add] synonym: "up regulation of endothelial cell proliferation" EXACT [] synonym: "up-regulation of endothelial cell proliferation" EXACT [] synonym: "upregulation of endothelial cell proliferation" EXACT [] is_a: GO:0001936 ! regulation of endothelial cell proliferation is_a: GO:0050679 ! positive regulation of epithelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001935 ! positively regulates endothelial cell proliferation relationship: RO:0002213 GO:0001935 ! positively regulates endothelial cell proliferation [Term] id: GO:0001940 name: male pronucleus namespace: cellular_component def: "The pronucleus originating from the spermatozoa that was involved in fertilization." [GOC:hjd, ISBN:0198506732] is_a: GO:0045120 ! pronucleus [Term] id: GO:0001944 name: vasculature development namespace: biological_process def: "The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism." [GOC:dph, UBERON:0002409] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002049 ! results in development of vasculature relationship: BFO:0000050 GO:0072359 ! part of circulatory system development relationship: RO:0002296 UBERON:0002049 ! results in development of vasculature [Term] id: GO:0001955 name: blood vessel maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for a blood vessel to attain its fully functional state." [GOC:dph] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 UBERON:0001981 ! results in maturation of blood vessel relationship: BFO:0000050 GO:0001568 ! part of blood vessel development relationship: RO:0002299 UBERON:0001981 ! results in maturation of blood vessel [Term] id: GO:0001956 name: positive regulation of neurotransmitter secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of a neurotransmitter." [GOC:hjd] synonym: "up regulation of neurotransmitter secretion" EXACT [] synonym: "up-regulation of neurotransmitter secretion" EXACT [] synonym: "upregulation of neurotransmitter secretion" EXACT [] is_a: GO:0046928 ! regulation of neurotransmitter secretion is_a: GO:0050806 ! positive regulation of synaptic transmission is_a: GO:0051590 ! positive regulation of neurotransmitter transport is_a: GO:1903532 ! positive regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007269 ! positively regulates neurotransmitter secretion relationship: RO:0002213 GO:0007269 ! positively regulates neurotransmitter secretion [Term] id: GO:0001957 name: intramembranous ossification namespace: biological_process def: "Direct ossification that occurs within mesenchyme or an accumulation of relatively unspecialized cells." [ISBN:0878932437] xref: Wikipedia:Intramembranous_ossification is_a: GO:0036072 ! direct ossification [Term] id: GO:0002009 name: morphogenesis of an epithelium namespace: biological_process def: "The process in which the anatomical structures of epithelia are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube." [GOC:dph, GOC:jl, GOC:tb, ISBN:0198506732] synonym: "epithelium morphogenesis" EXACT [] is_a: GO:0048729 ! tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000483 ! results in morphogenesis of epithelium relationship: BFO:0000050 GO:0060429 ! part of epithelium development relationship: RO:0002298 UBERON:0000483 ! results in morphogenesis of epithelium [Term] id: GO:0002011 name: morphogenesis of an epithelial sheet namespace: biological_process def: "The process in which the anatomical structures of an epithelial sheet are generated and organized. An epithelial sheet is a flat surface consisting of closely packed epithelial cells." [GOC:jl] is_a: GO:0002009 ! morphogenesis of an epithelium intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0010136 ! results in morphogenesis of epithelial sheet relationship: RO:0002298 UBERON:0010136 ! results in morphogenesis of epithelial sheet [Term] id: GO:0002027 name: regulation of heart rate namespace: biological_process def: "Any process that modulates the frequency or rate of heart contraction." [GOC:dph, GOC:tb, PMID:10358008] synonym: "cardiac chronotropy" EXACT [GOC:dph, GOC:tb] synonym: "regulation of heart contraction rate" EXACT [] synonym: "regulation of rate of heart contraction" EXACT [] is_a: GO:0008016 ! regulation of heart contraction [Term] id: GO:0002028 name: regulation of sodium ion transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph] synonym: "regulation of Na+ transport" EXACT [] synonym: "regulation of sodium transport" EXACT [] is_a: GO:0010959 ! regulation of metal ion transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006814 ! regulates (processual) sodium ion transport relationship: RO:0002211 GO:0006814 ! regulates (processual) sodium ion transport [Term] id: GO:0002052 name: positive regulation of neuroblast proliferation namespace: biological_process def: "Any process that activates or increases the rate of neuroblast proliferation." [GOC:dph] synonym: "up regulation of neuroblast proliferation" EXACT [] synonym: "up-regulation of neuroblast proliferation" EXACT [] synonym: "upregulation of neuroblast proliferation" EXACT [] is_a: GO:0050769 ! positive regulation of neurogenesis is_a: GO:1902692 ! regulation of neuroblast proliferation is_a: GO:2000179 ! positive regulation of neural precursor cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007405 ! positively regulates neuroblast proliferation relationship: RO:0002213 GO:0007405 ! positively regulates neuroblast proliferation [Term] id: GO:0002053 name: positive regulation of mesenchymal cell proliferation namespace: biological_process def: "The process of activating or increasing the rate or extent of mesenchymal cell proliferation. Mesenchymal cells are loosely organized embryonic cells." [GOC:dph] synonym: "up regulation of mesenchymal cell proliferation" EXACT [] synonym: "up-regulation of mesenchymal cell proliferation" EXACT [] synonym: "upregulation of mesenchymal cell proliferation" EXACT [] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0010464 ! regulation of mesenchymal cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0010463 ! positively regulates mesenchymal cell proliferation relationship: RO:0002213 GO:0010463 ! positively regulates mesenchymal cell proliferation [Term] id: GO:0002062 name: chondrocyte differentiation namespace: biological_process def: "The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte. A chondrocyte is a polymorphic cell that forms cartilage." [GOC:dph] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000138 ! results in acquisition of features of chondrocyte relationship: BFO:0000050 GO:0051216 ! part of cartilage development relationship: RO:0002315 CL:0000138 ! results in acquisition of features of chondrocyte [Term] id: GO:0002063 name: chondrocyte development namespace: biological_process def: "The process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate." [GOC:dph] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000138 ! results in development of chondrocyte relationship: BFO:0000050 GO:0002062 ! part of chondrocyte differentiation relationship: RO:0002296 CL:0000138 ! results in development of chondrocyte [Term] id: GO:0002064 name: epithelial cell development namespace: biological_process def: "The process whose specific outcome is the progression of an epithelial cell over time, from its formation to the mature structure. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface." [GOC:dph] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000066 ! results in development of epithelial cell relationship: BFO:0000050 GO:0030855 ! part of epithelial cell differentiation relationship: RO:0002296 CL:0000066 ! results in development of epithelial cell [Term] id: GO:0002065 name: columnar/cuboidal epithelial cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube." [GOC:dph] is_a: GO:0030855 ! epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000075 ! results in acquisition of features of columnar/cuboidal epithelial cell relationship: RO:0002315 CL:0000075 ! results in acquisition of features of columnar/cuboidal epithelial cell [Term] id: GO:0002066 name: columnar/cuboidal epithelial cell development namespace: biological_process def: "The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell over time, from its formation to the mature structure. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube." [GOC:dph] is_a: GO:0002064 ! epithelial cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000075 ! results in development of columnar/cuboidal epithelial cell relationship: BFO:0000050 GO:0002065 ! part of columnar/cuboidal epithelial cell differentiation relationship: RO:0002296 CL:0000075 ! results in development of columnar/cuboidal epithelial cell [Term] id: GO:0002067 name: glandular epithelial cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a glandular epithelial cell. A glandular epithelial cell is a columnar/cuboidal epithelial cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland." [GOC:dph] is_a: GO:0002065 ! columnar/cuboidal epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000150 ! results in acquisition of features of glandular epithelial cell relationship: RO:0002315 CL:0000150 ! results in acquisition of features of glandular epithelial cell [Term] id: GO:0002068 name: glandular epithelial cell development namespace: biological_process def: "The process whose specific outcome is the progression of a glandular epithelial cell over time, from its formation to the mature structure. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland." [GOC:dph] is_a: GO:0002066 ! columnar/cuboidal epithelial cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000150 ! results in development of glandular epithelial cell relationship: BFO:0000050 GO:0002067 ! part of glandular epithelial cell differentiation relationship: RO:0002296 CL:0000150 ! results in development of glandular epithelial cell [Term] id: GO:0002069 name: columnar/cuboidal epithelial cell maturation namespace: biological_process def: "The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell to attain its fully functional state. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube." [GOC:dph] is_a: GO:0002070 ! epithelial cell maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 CL:0000075 ! results in maturation of columnar/cuboidal epithelial cell relationship: BFO:0000050 GO:0002066 ! part of columnar/cuboidal epithelial cell development relationship: RO:0002299 CL:0000075 ! results in maturation of columnar/cuboidal epithelial cell [Term] id: GO:0002070 name: epithelial cell maturation namespace: biological_process def: "The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface." [GOC:dph] is_a: GO:0048469 ! cell maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 CL:0000066 ! results in maturation of epithelial cell relationship: BFO:0000050 GO:0002064 ! part of epithelial cell development relationship: RO:0002299 CL:0000066 ! results in maturation of epithelial cell [Term] id: GO:0002071 name: glandular epithelial cell maturation namespace: biological_process def: "The developmental process, independent of morphogenetic (shape) change, that is required for a glandular epithelial cell to attain its fully functional state. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland." [GOC:dph] is_a: GO:0002069 ! columnar/cuboidal epithelial cell maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 CL:0000150 ! results in maturation of glandular epithelial cell relationship: BFO:0000050 GO:0002068 ! part of glandular epithelial cell development relationship: RO:0002299 CL:0000150 ! results in maturation of glandular epithelial cell [Term] id: GO:0002072 name: optic cup morphogenesis involved in camera-type eye development namespace: biological_process def: "The invagination of the optic vesicle to form two-walled indentations, the optic cups, that will go on to form the retina. This process begins with the optic vesicle becoming a two-walled structure and its subsequent shape changes. It does not include the fate commitment of cells to become the pigmented retina and the neural retina. An example of this process is found in Mus musculus." [GOC:dph, GOC:mtg_sensu, GOC:sdb_2009, GOC:tb, ISBN:0878932437] synonym: "optic cup morphogenesis involved in camera-style eye development" EXACT [] is_a: GO:0016331 ! morphogenesis of embryonic epithelium intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003072 ! results in morphogenesis of optic cup relationship: BFO:0000050 GO:0060900 ! part of embryonic camera-type eye formation relationship: RO:0002298 UBERON:0003072 ! results in morphogenesis of optic cup [Term] id: GO:0002080 name: acrosomal membrane namespace: cellular_component def: "The membrane that surrounds the acrosomal lumen. The acrosome is a special type of lysosome in the head of a spermatozoon that contains acid hydrolases and is concerned with the breakdown of the outer membrane of the ovum during fertilization." [GOC:dph] is_a: GO:0030667 ! secretory granule membrane intersection_of: GO:0016020 ! membrane intersection_of: RO:0002007 GO:0001669 ! bounding layer of acrosomal vesicle relationship: RO:0002007 GO:0001669 ! bounding layer of acrosomal vesicle [Term] id: GO:0002085 name: inhibition of neuroepithelial cell differentiation namespace: biological_process def: "Any process that prevents the activation of neuroepithelial cell differentiation. Neuroepithelial cell differentiation is the process in which epiblast cells acquire specialized features of neuroepithelial cells." [GOC:dph, PMID:16678814] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis is_a: GO:0030857 ! negative regulation of epithelial cell differentiation is_a: GO:0045995 ! regulation of embryonic development is_a: GO:0048505 ! regulation of timing of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060563 ! negatively regulates neuroepithelial cell differentiation relationship: RO:0002212 GO:0060563 ! negatively regulates neuroepithelial cell differentiation [Term] id: GO:0002087 name: regulation of respiratory gaseous exchange by nervous system process namespace: biological_process def: "A process carried out by the nervous system that is required for the proper control of respiratory gaseous exchange. This process occurs in the respiratory center of the brain in vertebrates." [GOC:dph, GOC:tb, PMID:12458206] synonym: "neurological control of breathing" EXACT [GOC:dph, GOC:tb] synonym: "regulation of respiratory gaseous exchange by neurological system process" EXACT [] is_a: GO:0044065 ! regulation of respiratory system process is_a: GO:0050877 ! nervous system process intersection_of: GO:0050877 ! nervous system process intersection_of: RO:0002211 GO:0007585 ! regulates (processual) respiratory gaseous exchange by respiratory system [Term] id: GO:0002088 name: lens development in camera-type eye namespace: biological_process def: "The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus." [GOC:dph, ISBN:0582064333] synonym: "lens development" EXACT [] synonym: "lens development in camera-style eye" EXACT [] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000965 ! results in development of lens of camera-type eye relationship: BFO:0000050 GO:0043010 ! part of camera-type eye development relationship: RO:0002296 UBERON:0000965 ! results in development of lens of camera-type eye [Term] id: GO:0002089 name: lens morphogenesis in camera-type eye namespace: biological_process def: "The process in which the anatomical structures of the lens are generated and organized. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus." [GOC:dph, GOC:mtg_sensu] synonym: "lens morphogenesis" EXACT [] synonym: "lens morphogenesis in camera-style eye" EXACT [] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000965 ! results in morphogenesis of lens of camera-type eye relationship: BFO:0000050 GO:0002088 ! part of lens development in camera-type eye relationship: BFO:0000050 GO:0048593 ! part of camera-type eye morphogenesis relationship: RO:0002298 UBERON:0000965 ! results in morphogenesis of lens of camera-type eye [Term] id: GO:0002119 name: nematode larval development namespace: biological_process def: "The process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew." [GOC:ems, GOC:kmv] is_a: GO:0002164 ! larval development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0009850 ! results in development of nematode larva relationship: RO:0002160 NCBITaxon:33213 ! only in taxon Bilateria relationship: RO:0002162 NCBITaxon:33213 {all_only="true"} ! in taxon Bilateria relationship: RO:0002296 UBERON:0009850 ! results in development of nematode larva [Term] id: GO:0002164 name: larval development namespace: biological_process def: "The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. The larva is the early, immature form of an that at birth or hatching is fundamentally unlike its parent and must metamorphose before assuming the adult characters." [GOC:jid, ISBN:0877795088] is_a: GO:0007275 ! multicellular organism development is_a: GO:0009791 ! post-embryonic development [Term] id: GO:0002165 name: instar larval or pupal development namespace: biological_process def: "The process whose specific outcome is the progression of the instar larva or pupa over time, from its formation to the mature structure. An example of this process is found in Drosophila melanogaster." [GOC:jid, GOC:mtg_sensu] is_a: GO:0007275 ! multicellular organism development is_a: GO:0009791 ! post-embryonic development relationship: RO:0002160 NCBITaxon:6656 ! only in taxon Arthropoda relationship: RO:0002162 NCBITaxon:6656 {all_only="true"} ! in taxon Arthropoda [Term] id: GO:0002176 name: male germ cell proliferation namespace: biological_process def: "The multiplication or reproduction of male germ cells, resulting in the expansion of a cell population." [GOC:hjd] is_a: GO:0036093 ! germ cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000015 ! acts on population of male germ cell relationship: RO:0012003 CL:0000015 ! acts on population of male germ cell creation_date: 2010-11-18T02:35:14Z [Term] id: GO:0002213 name: defense response to insect namespace: biological_process def: "A response to protect an organism from a directly detected or perceived external threat from an insect or insects to that organism." [GOC:add] synonym: "physiological defense response to insect" EXACT [] is_a: GO:0006952 ! defense response intersection_of: GO:0006952 ! defense response intersection_of: RO:0004009 NCBITaxon:50557 ! has primary input Insecta relationship: RO:0004009 NCBITaxon:50557 ! has primary input Insecta [Term] id: GO:0002215 name: defense response to nematode namespace: biological_process def: "A response to protect an organism from a directly detected or perceived external threat from a nematode or nematodes, which results in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack." [GOC:add, PMID:11516579, PMID:14506883] synonym: "physiological defense response to nematode" EXACT [] is_a: GO:0006952 ! defense response intersection_of: GO:0006952 ! defense response intersection_of: RO:0004009 NCBITaxon:6231 ! has primary input Nematoda relationship: RO:0004009 NCBITaxon:6231 ! has primary input Nematoda [Term] id: GO:0002244 name: hematopoietic progenitor cell differentiation namespace: biological_process def: "The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells." [GOC:add, GOC:rl, ISBN:0781735149, PMID:16551251] synonym: "haematopoietic progenitor cell differentiation" EXACT [] synonym: "haemopoietic progenitor cell differentiation" EXACT [] synonym: "hemopoietic progenitor cell differentiation" EXACT [] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0008001 ! results in acquisition of features of hematopoietic precursor cell relationship: BFO:0000050 GO:0030097 ! part of hemopoiesis relationship: RO:0002315 CL:0008001 ! results in acquisition of features of hematopoietic precursor cell [Term] id: GO:0002250 name: adaptive immune response namespace: biological_process def: "An immune response mediated by cells expressing specific receptors for antigens produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory)." [GO_REF:0000022, GOC:add, ISBN:0781735149] synonym: "acquired immune response" EXACT [ISBN:068340007X] synonym: "immune memory response" EXACT [GOC:add] xref: Wikipedia:Adaptive_immune_system is_a: GO:0006955 ! immune response relationship: RO:0002160 NCBITaxon:33208 ! only in taxon Metazoa relationship: RO:0002162 NCBITaxon:33208 {all_only="true"} ! in taxon Metazoa [Term] id: GO:0002251 name: organ or tissue specific immune response namespace: biological_process def: "An immune response taking place in an organ or tissues such as the liver, brain, mucosa, or nervous system tissues." [GO_REF:0000022, GOC:jal] synonym: "immune response in organ or tissue" EXACT [] is_a: GO:0006955 ! immune response [Term] id: GO:0002252 name: immune effector process namespace: biological_process def: "Any process of the immune system that executes a component of an immune response. An effector immune process takes place after its activation." [GO_REF:0000022, GOC:add, ISBN:0781735149] is_a: GO:0002376 ! immune system process [Term] id: GO:0002260 name: lymphocyte homeostasis namespace: biological_process def: "The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus." [GOC:add, PMID:15826826, PMID:16319493, PMID:16551252, PMID:16551262] is_a: GO:0001776 ! leukocyte homeostasis intersection_of: GO:0048872 ! homeostasis of number of cells intersection_of: RO:0012003 CL:0000542 ! acts on population of lymphocyte relationship: RO:0012003 CL:0000542 ! acts on population of lymphocyte [Term] id: GO:0002262 name: myeloid cell homeostasis namespace: biological_process def: "The process of regulating the proliferation and elimination of myeloid cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus." [CL:0000763, GOC:add] is_a: GO:0002376 ! immune system process is_a: GO:0048872 ! homeostasis of number of cells intersection_of: GO:0048872 ! homeostasis of number of cells intersection_of: RO:0012003 CL:0000763 ! acts on population of myeloid cell relationship: RO:0012003 CL:0000763 ! acts on population of myeloid cell [Term] id: GO:0002263 name: cell activation involved in immune response namespace: biological_process def: "A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response." [GO_REF:0000022, GOC:add, ISBN:0781735149] is_a: GO:0001775 ! cell activation is_a: GO:0002252 ! immune effector process intersection_of: GO:0001775 ! cell activation intersection_of: BFO:0000050 GO:0006955 ! part of immune response relationship: BFO:0000050 GO:0006955 ! part of immune response [Term] id: GO:0002264 name: endothelial cell activation involved in immune response namespace: biological_process def: "A change in the morphology or behavior of an endothelial cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response." [GOC:add, ISBN:0781735149] is_a: GO:0002263 ! cell activation involved in immune response is_a: GO:0042118 ! endothelial cell activation intersection_of: GO:0042118 ! endothelial cell activation intersection_of: BFO:0000050 GO:0006955 ! part of immune response [Term] id: GO:0002269 name: leukocyte activation involved in inflammatory response namespace: biological_process def: "A change in the morphology or behavior of a leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an inflammatory response." [GOC:add, ISBN:0781735149] is_a: GO:0045321 ! leukocyte activation intersection_of: GO:0045321 ! leukocyte activation intersection_of: BFO:0000050 GO:0006954 ! part of inflammatory response relationship: BFO:0000050 GO:0006954 ! part of inflammatory response [Term] id: GO:0002274 name: myeloid leukocyte activation namespace: biological_process def: "A change in the morphology or behavior of a myeloid leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand." [GOC:add, ISBN:0781735149] synonym: "myeloid leucocyte activation" EXACT [] is_a: GO:0045321 ! leukocyte activation intersection_of: GO:0001775 ! cell activation intersection_of: RO:0004009 CL:0000766 ! has primary input myeloid leukocyte relationship: RO:0004009 CL:0000766 ! has primary input myeloid leukocyte [Term] id: GO:0002285 name: lymphocyte activation involved in immune response namespace: biological_process def: "A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response." [GOC:add, ISBN:0781735149] is_a: GO:0002366 ! leukocyte activation involved in immune response is_a: GO:0046649 ! lymphocyte activation intersection_of: GO:0046649 ! lymphocyte activation intersection_of: BFO:0000050 GO:0006955 ! part of immune response [Term] id: GO:0002286 name: T cell activation involved in immune response namespace: biological_process def: "The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response." [GOC:add, ISBN:0781735149] is_a: GO:0002285 ! lymphocyte activation involved in immune response is_a: GO:0042110 ! T cell activation intersection_of: GO:0042110 ! T cell activation intersection_of: BFO:0000050 GO:0006955 ! part of immune response [Term] id: GO:0002292 name: T cell differentiation involved in immune response namespace: biological_process def: "The process in which an antigenically naive T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells." [GOC:add, ISBN:0781735149] is_a: GO:0002286 ! T cell activation involved in immune response is_a: GO:0030217 ! T cell differentiation intersection_of: GO:0030217 ! T cell differentiation intersection_of: BFO:0000050 GO:0006955 ! part of immune response [Term] id: GO:0002309 name: T cell proliferation involved in immune response namespace: biological_process def: "The expansion of a T cell population by cell division as part of an immune response." [GOC:add, ISBN:0781735149] is_a: GO:0002286 ! T cell activation involved in immune response is_a: GO:0042098 ! T cell proliferation intersection_of: GO:0042098 ! T cell proliferation intersection_of: BFO:0000050 GO:0006955 ! part of immune response [Term] id: GO:0002318 name: myeloid progenitor cell differentiation namespace: biological_process def: "The process in which a precursor cell type acquires the specialized features of a myeloid progenitor cell. Myeloid progenitor cells include progenitor cells for any of the myeloid lineages." [GOC:add, PMID:16551264] is_a: GO:0002244 ! hematopoietic progenitor cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000839 ! results in acquisition of features of myeloid lineage restricted progenitor cell relationship: RO:0002315 CL:0000839 ! results in acquisition of features of myeloid lineage restricted progenitor cell [Term] id: GO:0002320 name: lymphoid progenitor cell differentiation namespace: biological_process def: "The process in which a precursor cell type acquires the specialized features of a lymphoid progenitor cell. Lymphoid progenitor cells include progenitor cells for any of the lymphoid lineages." [GOC:add, PMID:16551251, PMID:16551264] is_a: GO:0002244 ! hematopoietic progenitor cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000838 ! results in acquisition of features of lymphoid lineage restricted progenitor cell relationship: RO:0002315 CL:0000838 ! results in acquisition of features of lymphoid lineage restricted progenitor cell [Term] id: GO:0002351 name: serotonin production involved in inflammatory response namespace: biological_process def: "The synthesis or release of serotonin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels." [GOC:add, ISBN:0781735149, PMID:16730260] is_a: GO:0002532 ! production of molecular mediator involved in inflammatory response [Term] id: GO:0002366 name: leukocyte activation involved in immune response namespace: biological_process def: "A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response." [GOC:add, ISBN:0781735149] is_a: GO:0002263 ! cell activation involved in immune response is_a: GO:0045321 ! leukocyte activation intersection_of: GO:0045321 ! leukocyte activation intersection_of: BFO:0000050 GO:0006955 ! part of immune response [Term] id: GO:0002367 name: cytokine production involved in immune response namespace: biological_process def: "The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus contributing to an immune response, resulting in an increase in its intracellular or extracellular levels." [GO_REF:0000022, GOC:add, ISBN:0781735149] is_a: GO:0001816 ! cytokine production is_a: GO:0002440 ! production of molecular mediator of immune response intersection_of: GO:0001816 ! cytokine production intersection_of: BFO:0000050 GO:0006955 ! part of immune response relationship: BFO:0000050 GO:0006955 ! part of immune response [Term] id: GO:0002369 name: T cell cytokine production namespace: biological_process def: "Any process that contributes to cytokine production by a T cell." [GOC:add, ISBN:0781735149] synonym: "T lymphocyte cytokine production" EXACT [] synonym: "T-cell cytokine production" EXACT [] synonym: "T-lymphocyte cytokine production" EXACT [] is_a: GO:0002367 ! cytokine production involved in immune response is_a: GO:0002456 ! T cell mediated immunity intersection_of: GO:0001816 ! cytokine production intersection_of: RO:0002608 CL:0000084 ! process has causal agent T cell [Term] id: GO:0002371 name: dendritic cell cytokine production namespace: biological_process def: "Any process that contributes to cytokine production by a dendritic cell." [GOC:add, ISBN:0781735149] is_a: GO:0002367 ! cytokine production involved in immune response is_a: GO:0002443 ! leukocyte mediated immunity intersection_of: GO:0001816 ! cytokine production intersection_of: RO:0002608 CL:0000451 ! process has causal agent dendritic cell relationship: RO:0002608 CL:0000451 ! process has causal agent dendritic cell [Term] id: GO:0002376 name: immune system process namespace: biological_process def: "Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats." [GO_REF:0000022, GOC:add] xref: Wikipedia:Immune_system is_a: GO:0008150 ! biological_process [Term] id: GO:0002384 name: hepatic immune response namespace: biological_process def: "An immune response taking place in the liver." [GO_REF:0000022, GOC:jal, ISBN:0781735149] is_a: GO:0002251 ! organ or tissue specific immune response intersection_of: GO:0006955 ! immune response intersection_of: BFO:0000066 UBERON:0002107 ! occurs in liver relationship: BFO:0000066 UBERON:0002107 ! occurs in liver relationship: RO:0002160 NCBITaxon:7742 ! only in taxon Vertebrata relationship: RO:0002162 NCBITaxon:7742 {all_only="true"} ! in taxon Vertebrata [Term] id: GO:0002396 name: MHC protein complex assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form an MHC protein complex." [GOC:add, ISBN:0781735149, PMID:15771591, PMID:15928678] is_a: GO:0065003 ! protein-containing complex assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0042611 ! results in assembly of MHC protein complex relationship: RO:0002588 GO:0042611 ! results in assembly of MHC protein complex [Term] id: GO:0002399 name: MHC class II protein complex assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form an MHC class II protein complex." [GOC:add, ISBN:0781735149, PMID:15771591] is_a: GO:0002396 ! MHC protein complex assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0042613 ! results in assembly of MHC class II protein complex relationship: RO:0002588 GO:0042613 ! results in assembly of MHC class II protein complex [Term] id: GO:0002440 name: production of molecular mediator of immune response namespace: biological_process def: "The synthesis or release of any molecular mediator of the immune response, resulting in an increase in its intracellular or extracellular levels." [GO_REF:0000022, GOC:add, ISBN:0781735149] is_a: GO:0002376 ! immune system process is_a: GO:0010467 ! gene expression [Term] id: GO:0002442 name: serotonin secretion involved in inflammatory response namespace: biological_process def: "The regulated release of serotonin by a cell as part of an inflammatory response." [GOC:add, ISBN:0781735149] is_a: GO:0001820 ! serotonin secretion intersection_of: GO:0001820 ! serotonin secretion intersection_of: BFO:0000050 GO:0006954 ! part of inflammatory response relationship: BFO:0000050 GO:0002351 ! part of serotonin production involved in inflammatory response [Term] id: GO:0002443 name: leukocyte mediated immunity namespace: biological_process def: "Any process involved in the carrying out of an immune response by a leukocyte." [GO_REF:0000022, GOC:add, ISBN:0781735149] synonym: "immune cell effector process" EXACT [] synonym: "immune cell mediated immunity" EXACT [] synonym: "leucocyte immune effector process" EXACT [] synonym: "leucocyte mediated immunity" EXACT [] synonym: "leukocyte immune effector process" EXACT [] is_a: GO:0002252 ! immune effector process intersection_of: GO:0002376 ! immune system process intersection_of: RO:0002608 CL:0000738 ! process has causal agent leukocyte relationship: RO:0002160 NCBITaxon:7742 ! only in taxon Vertebrata relationship: RO:0002162 NCBITaxon:7742 {all_only="true"} ! in taxon Vertebrata relationship: RO:0002608 CL:0000738 ! process has causal agent leukocyte [Term] id: GO:0002444 name: myeloid leukocyte mediated immunity namespace: biological_process def: "Any process involved in the carrying out of an immune response by a myeloid leukocyte." [GO_REF:0000022, GOC:add, ISBN:0781735149] synonym: "myeloid leucocyte immune effector process" EXACT [] synonym: "myeloid leucocyte mediated immunity" EXACT [] synonym: "myeloid leukocyte immune effector process" EXACT [] is_a: GO:0002443 ! leukocyte mediated immunity intersection_of: GO:0002376 ! immune system process intersection_of: RO:0002608 CL:0000766 ! process has causal agent myeloid leukocyte relationship: RO:0002608 CL:0000766 ! process has causal agent myeloid leukocyte [Term] id: GO:0002449 name: lymphocyte mediated immunity namespace: biological_process def: "Any process involved in the carrying out of an immune response by a lymphocyte." [GO_REF:0000022, GOC:add, ISBN:0781735149] is_a: GO:0002443 ! leukocyte mediated immunity intersection_of: GO:0002376 ! immune system process intersection_of: RO:0002608 CL:0000542 ! process has causal agent lymphocyte relationship: RO:0002608 CL:0000542 ! process has causal agent lymphocyte [Term] id: GO:0002456 name: T cell mediated immunity namespace: biological_process def: "Any process involved in the carrying out of an immune response by a T cell." [GO_REF:0000022, GOC:add, ISBN:0781735149] synonym: "T lymphocyte mediated immunity" EXACT [] synonym: "T-cell mediated immunity" EXACT [] synonym: "T-lymphocyte mediated immunity" EXACT [] is_a: GO:0002449 ! lymphocyte mediated immunity is_a: GO:0002460 ! adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains intersection_of: GO:0002376 ! immune system process intersection_of: RO:0002608 CL:0000084 ! process has causal agent T cell relationship: RO:0002608 CL:0000084 ! process has causal agent T cell [Term] id: GO:0002457 name: T cell antigen processing and presentation namespace: biological_process def: "The process in which a T cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex." [GOC:add, PMID:11417857, PMID:15120183] synonym: "T lymphocyte antigen processing and presentation" EXACT [] synonym: "T-cell antigen processing and presentation" EXACT [] synonym: "T-lymphocyte antigen processing and presentation" EXACT [] is_a: GO:0019882 ! antigen processing and presentation intersection_of: GO:0019882 ! antigen processing and presentation intersection_of: BFO:0000066 CL:0000084 ! occurs in T cell relationship: BFO:0000050 GO:0002456 ! part of T cell mediated immunity relationship: BFO:0000066 CL:0000084 ! occurs in T cell [Term] id: GO:0002460 name: adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains namespace: biological_process def: "An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains. Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies) produced by B cells. The first encounter with antigen elicits a primary immune response that is slow and not of great magnitude. T and B cells selected by antigen become activated and undergo clonal expansion. A fraction of antigen-reactive T and B cells become memory cells, whereas others differentiate into effector cells. The memory cells generated during the primary response enable a much faster and stronger secondary immune response upon subsequent exposures to the same antigen (immunological memory). An example of this is the adaptive immune response found in Mus musculus." [GOC:add, GOC:mtg_sensu, ISBN:0781735149, ISBN:1405196831] is_a: GO:0002250 ! adaptive immune response [Term] id: GO:0002468 name: dendritic cell antigen processing and presentation namespace: biological_process def: "The process in which a dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex." [GOC:add, ISBN:0781735149, PMID:15771591] is_a: GO:0019882 ! antigen processing and presentation intersection_of: GO:0019882 ! antigen processing and presentation intersection_of: BFO:0000066 CL:0000451 ! occurs in dendritic cell relationship: BFO:0000066 CL:0000451 ! occurs in dendritic cell [Term] id: GO:0002504 name: antigen processing and presentation of peptide or polysaccharide antigen via MHC class II namespace: biological_process def: "The process in which an antigen-presenting cell expresses antigen (peptide or polysaccharide) on its cell surface in association with an MHC class II protein complex." [GOC:add, ISBN:0781735149, PMID:15531770, PMID:15771591, PMID:16153240] synonym: "peptide or polysaccharide antigen processing and presentation of via MHC class II" EXACT [] is_a: GO:0019882 ! antigen processing and presentation [Term] id: GO:0002520 name: immune system development namespace: biological_process def: "The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process." [GOC:add, GOC:dph] is_a: GO:0002376 ! immune system process is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002405 ! results in development of immune system relationship: RO:0002296 UBERON:0002405 ! results in development of immune system [Term] id: GO:0002521 name: leukocyte differentiation namespace: biological_process def: "The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a leukocyte. A leukocyte is an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue." [CL:0000738, GOC:add, PMID:16551264] synonym: "immune cell differentiation" EXACT [] synonym: "leucocyte differentiation" EXACT [] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000738 ! results in acquisition of features of leukocyte relationship: BFO:0000050 GO:0030097 ! part of hemopoiesis relationship: RO:0002315 CL:0000738 ! results in acquisition of features of leukocyte [Term] id: GO:0002522 name: leukocyte migration involved in immune response namespace: biological_process def: "The movement of a leukocyte within or between different tissues and organs of the body as part of an immune response." [GOC:add, ISBN:0781735149, PMID:14680625, PMID:14708592, PMID:7507411, PMID:8600538] synonym: "immune cell migration during immune response" EXACT [] synonym: "immune cell trafficking during immune response" EXACT [] synonym: "leucocyte migration during immune response" EXACT [] synonym: "leucocyte trafficking during immune response" EXACT [] synonym: "leukocyte trafficking during immune response" EXACT [] is_a: GO:0002252 ! immune effector process is_a: GO:0050900 ! leukocyte migration intersection_of: GO:0050900 ! leukocyte migration intersection_of: BFO:0000050 GO:0006955 ! part of immune response relationship: BFO:0000050 GO:0006955 ! part of immune response [Term] id: GO:0002523 name: leukocyte migration involved in inflammatory response namespace: biological_process def: "The movement of a leukocyte within or between different tissues and organs of the body contributing to an inflammatory response." [GOC:add, ISBN:0781735149, PMID:14680625, PMID:14708592, PMID:7507411, PMID:8600538] is_a: GO:0050900 ! leukocyte migration intersection_of: GO:0050900 ! leukocyte migration intersection_of: BFO:0000050 GO:0006954 ! part of inflammatory response relationship: BFO:0000050 GO:0006954 ! part of inflammatory response [Term] id: GO:0002532 name: production of molecular mediator involved in inflammatory response namespace: biological_process def: "The synthesis or release of any molecular mediator of the inflammatory response following an inflammatory stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:add, GOC:dph, GOC:tb, ISBN:0781735149] is_a: GO:0032501 ! multicellular organismal process relationship: BFO:0000050 GO:0006954 ! part of inflammatory response [Term] id: GO:0002534 name: cytokine production involved in inflammatory response namespace: biological_process def: "The synthesis or release of a cytokine following a inflammatory stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels." [GOC:add, ISBN:0781735149] is_a: GO:0001816 ! cytokine production is_a: GO:0002532 ! production of molecular mediator involved in inflammatory response intersection_of: GO:0001816 ! cytokine production intersection_of: BFO:0000050 GO:0006954 ! part of inflammatory response [Term] id: GO:0002572 name: pro-T cell differentiation namespace: biological_process def: "The process in which a precursor cell type acquires the specialized features of a pro-T cell. Pro-T cells are the earliest stage of the T cell lineage but are not fully committed." [GOC:add, ISBN:0781735149] synonym: "pro-T lymphocyte differentiation" EXACT [] is_a: GO:0002320 ! lymphoid progenitor cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000827 ! results in acquisition of features of pro-T cell relationship: BFO:0000050 GO:0030217 ! part of T cell differentiation relationship: RO:0002315 CL:0000827 ! results in acquisition of features of pro-T cell [Term] id: GO:0002573 name: myeloid leukocyte differentiation namespace: biological_process def: "The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte lineage." [GOC:add, PMID:16551251] synonym: "myeloid leucocyte differentiation" EXACT [] is_a: GO:0002521 ! leukocyte differentiation is_a: GO:0030099 ! myeloid cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000766 ! results in acquisition of features of myeloid leukocyte relationship: RO:0002315 CL:0000766 ! results in acquisition of features of myeloid leukocyte [Term] id: GO:0002577 name: regulation of antigen processing and presentation namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of antigen processing and presentation." [GOC:add] is_a: GO:0002682 ! regulation of immune system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0019882 ! regulates (processual) antigen processing and presentation relationship: RO:0002211 GO:0019882 ! regulates (processual) antigen processing and presentation [Term] id: GO:0002578 name: negative regulation of antigen processing and presentation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation." [GOC:add] synonym: "down regulation of antigen processing and presentation" EXACT [] synonym: "down-regulation of antigen processing and presentation" EXACT [] synonym: "downregulation of antigen processing and presentation" EXACT [] is_a: GO:0002577 ! regulation of antigen processing and presentation is_a: GO:0002683 ! negative regulation of immune system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0019882 ! negatively regulates antigen processing and presentation relationship: RO:0002212 GO:0019882 ! negatively regulates antigen processing and presentation [Term] id: GO:0002579 name: positive regulation of antigen processing and presentation namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation." [GOC:add] synonym: "up regulation of antigen processing and presentation" EXACT [] synonym: "up-regulation of antigen processing and presentation" EXACT [] synonym: "upregulation of antigen processing and presentation" EXACT [] is_a: GO:0002577 ! regulation of antigen processing and presentation is_a: GO:0002684 ! positive regulation of immune system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0019882 ! positively regulates antigen processing and presentation relationship: RO:0002213 GO:0019882 ! positively regulates antigen processing and presentation [Term] id: GO:0002580 name: regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II." [GOC:add] synonym: "regulation of peptide or polysaccharide antigen processing and presentation via MHC class II" EXACT [] is_a: GO:0002577 ! regulation of antigen processing and presentation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002504 ! regulates (processual) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II relationship: RO:0002211 GO:0002504 ! regulates (processual) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [Term] id: GO:0002581 name: negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II." [GOC:add] synonym: "down regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" EXACT [] synonym: "down-regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" EXACT [] synonym: "downregulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" EXACT [] synonym: "negative regulation of peptide or polysaccharide antigen processing and presentation via MHC class II" EXACT [] is_a: GO:0002578 ! negative regulation of antigen processing and presentation is_a: GO:0002580 ! regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002504 ! negatively regulates antigen processing and presentation of peptide or polysaccharide antigen via MHC class II relationship: RO:0002212 GO:0002504 ! negatively regulates antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [Term] id: GO:0002582 name: positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II." [GOC:add] synonym: "positive regulation of peptide or polysaccharide antigen processing and presentation via MHC class II" EXACT [] synonym: "up regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" EXACT [] synonym: "up-regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" EXACT [] synonym: "upregulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" EXACT [] is_a: GO:0002579 ! positive regulation of antigen processing and presentation is_a: GO:0002580 ! regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002504 ! positively regulates antigen processing and presentation of peptide or polysaccharide antigen via MHC class II relationship: RO:0002213 GO:0002504 ! positively regulates antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [Term] id: GO:0002604 name: regulation of dendritic cell antigen processing and presentation namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of dendritic cell antigen processing and presentation." [GOC:add] is_a: GO:0002577 ! regulation of antigen processing and presentation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002468 ! regulates (processual) dendritic cell antigen processing and presentation relationship: RO:0002211 GO:0002468 ! regulates (processual) dendritic cell antigen processing and presentation [Term] id: GO:0002605 name: negative regulation of dendritic cell antigen processing and presentation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell antigen processing and presentation." [GOC:add] synonym: "down regulation of dendritic cell antigen processing and presentation" EXACT [] synonym: "down-regulation of dendritic cell antigen processing and presentation" EXACT [] synonym: "downregulation of dendritic cell antigen processing and presentation" EXACT [] is_a: GO:0002578 ! negative regulation of antigen processing and presentation is_a: GO:0002604 ! regulation of dendritic cell antigen processing and presentation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002468 ! negatively regulates dendritic cell antigen processing and presentation relationship: RO:0002212 GO:0002468 ! negatively regulates dendritic cell antigen processing and presentation [Term] id: GO:0002606 name: positive regulation of dendritic cell antigen processing and presentation namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of dendritic cell antigen processing and presentation." [GOC:add] synonym: "up regulation of dendritic cell antigen processing and presentation" EXACT [] synonym: "up-regulation of dendritic cell antigen processing and presentation" EXACT [] synonym: "upregulation of dendritic cell antigen processing and presentation" EXACT [] is_a: GO:0002579 ! positive regulation of antigen processing and presentation is_a: GO:0002604 ! regulation of dendritic cell antigen processing and presentation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002468 ! positively regulates dendritic cell antigen processing and presentation relationship: RO:0002213 GO:0002468 ! positively regulates dendritic cell antigen processing and presentation [Term] id: GO:0002625 name: regulation of T cell antigen processing and presentation namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of T cell antigen processing and presentation." [GOC:add] synonym: "regulation of T lymphocyte antigen processing and presentation" EXACT [] synonym: "regulation of T-cell antigen processing and presentation" EXACT [] synonym: "regulation of T-lymphocyte antigen processing and presentation" EXACT [] is_a: GO:0002577 ! regulation of antigen processing and presentation is_a: GO:0002709 ! regulation of T cell mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002457 ! regulates (processual) T cell antigen processing and presentation relationship: RO:0002211 GO:0002457 ! regulates (processual) T cell antigen processing and presentation [Term] id: GO:0002626 name: negative regulation of T cell antigen processing and presentation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell antigen processing and presentation." [GOC:add] synonym: "down regulation of T cell antigen processing and presentation" EXACT [] synonym: "down-regulation of T cell antigen processing and presentation" EXACT [] synonym: "downregulation of T cell antigen processing and presentation" EXACT [] synonym: "negative regulation of T lymphocyte antigen processing and presentation" EXACT [] synonym: "negative regulation of T-cell antigen processing and presentation" EXACT [] synonym: "negative regulation of T-lymphocyte antigen processing and presentation" EXACT [] is_a: GO:0002578 ! negative regulation of antigen processing and presentation is_a: GO:0002625 ! regulation of T cell antigen processing and presentation is_a: GO:0002710 ! negative regulation of T cell mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002457 ! negatively regulates T cell antigen processing and presentation relationship: RO:0002212 GO:0002457 ! negatively regulates T cell antigen processing and presentation [Term] id: GO:0002627 name: positive regulation of T cell antigen processing and presentation namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of T cell antigen processing and presentation." [GOC:add] synonym: "positive regulation of T lymphocyte antigen processing and presentation" EXACT [] synonym: "positive regulation of T-cell antigen processing and presentation" EXACT [] synonym: "positive regulation of T-lymphocyte antigen processing and presentation" EXACT [] synonym: "up regulation of T cell antigen processing and presentation" EXACT [] synonym: "up-regulation of T cell antigen processing and presentation" EXACT [] synonym: "upregulation of T cell antigen processing and presentation" EXACT [] is_a: GO:0002579 ! positive regulation of antigen processing and presentation is_a: GO:0002625 ! regulation of T cell antigen processing and presentation is_a: GO:0002711 ! positive regulation of T cell mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002457 ! positively regulates T cell antigen processing and presentation relationship: RO:0002213 GO:0002457 ! positively regulates T cell antigen processing and presentation [Term] id: GO:0002682 name: regulation of immune system process namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of an immune system process." [GOC:add] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002376 ! regulates (processual) immune system process relationship: RO:0002211 GO:0002376 ! regulates (processual) immune system process [Term] id: GO:0002683 name: negative regulation of immune system process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process." [GOC:add] synonym: "down regulation of immune system process" EXACT [] synonym: "down-regulation of immune system process" EXACT [] synonym: "downregulation of immune system process" EXACT [] is_a: GO:0002682 ! regulation of immune system process is_a: GO:0048519 ! negative regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002376 ! negatively regulates immune system process relationship: RO:0002212 GO:0002376 ! negatively regulates immune system process [Term] id: GO:0002684 name: positive regulation of immune system process namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of an immune system process." [GOC:add] synonym: "up regulation of immune system process" EXACT [] synonym: "up-regulation of immune system process" EXACT [] synonym: "upregulation of immune system process" EXACT [] is_a: GO:0002682 ! regulation of immune system process is_a: GO:0048518 ! positive regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002376 ! positively regulates immune system process relationship: RO:0002213 GO:0002376 ! positively regulates immune system process [Term] id: GO:0002685 name: regulation of leukocyte migration namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of leukocyte migration." [GOC:add] synonym: "regulation of immune cell migration" EXACT [] synonym: "regulation of leucocyte migration" EXACT [] is_a: GO:0002682 ! regulation of immune system process is_a: GO:0030334 ! regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0050900 ! regulates (processual) leukocyte migration relationship: RO:0002211 GO:0050900 ! regulates (processual) leukocyte migration [Term] id: GO:0002686 name: negative regulation of leukocyte migration namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte migration." [GOC:add] synonym: "down regulation of leukocyte migration" EXACT [] synonym: "down-regulation of leukocyte migration" EXACT [] synonym: "downregulation of leukocyte migration" EXACT [] synonym: "negative regulation of immune cell migration" EXACT [] synonym: "negative regulation of leucocyte migration" EXACT [] is_a: GO:0002683 ! negative regulation of immune system process is_a: GO:0002685 ! regulation of leukocyte migration is_a: GO:0030336 ! negative regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0050900 ! negatively regulates leukocyte migration relationship: RO:0002212 GO:0050900 ! negatively regulates leukocyte migration [Term] id: GO:0002687 name: positive regulation of leukocyte migration namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of leukocyte migration." [GOC:add] synonym: "positive regulation of immune cell migration" EXACT [] synonym: "positive regulation of leucocyte migration" EXACT [] synonym: "up regulation of leukocyte migration" EXACT [] synonym: "up-regulation of leukocyte migration" EXACT [] synonym: "upregulation of leukocyte migration" EXACT [] is_a: GO:0002684 ! positive regulation of immune system process is_a: GO:0002685 ! regulation of leukocyte migration is_a: GO:0030335 ! positive regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0050900 ! positively regulates leukocyte migration relationship: RO:0002213 GO:0050900 ! positively regulates leukocyte migration [Term] id: GO:0002694 name: regulation of leukocyte activation namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of leukocyte activation." [GOC:add] synonym: "regulation of immune cell activation" EXACT [] synonym: "regulation of leucocyte activation" EXACT [] is_a: GO:0002682 ! regulation of immune system process is_a: GO:0050865 ! regulation of cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0045321 ! regulates (processual) leukocyte activation relationship: RO:0002211 GO:0045321 ! regulates (processual) leukocyte activation [Term] id: GO:0002695 name: negative regulation of leukocyte activation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte activation." [GOC:add] synonym: "down regulation of leukocyte activation" EXACT [] synonym: "down-regulation of leukocyte activation" EXACT [] synonym: "downregulation of leukocyte activation" EXACT [] synonym: "negative regulation of immune cell activation" EXACT [] synonym: "negative regulation of leucocyte activation" EXACT [] is_a: GO:0002683 ! negative regulation of immune system process is_a: GO:0002694 ! regulation of leukocyte activation is_a: GO:0050866 ! negative regulation of cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0045321 ! negatively regulates leukocyte activation relationship: RO:0002212 GO:0045321 ! negatively regulates leukocyte activation [Term] id: GO:0002696 name: positive regulation of leukocyte activation namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of leukocyte activation." [GOC:add] synonym: "positive regulation of immune cell activation" EXACT [] synonym: "positive regulation of leucocyte activation" EXACT [] synonym: "up regulation of leukocyte activation" EXACT [] synonym: "up-regulation of leukocyte activation" EXACT [] synonym: "upregulation of leukocyte activation" EXACT [] is_a: GO:0002684 ! positive regulation of immune system process is_a: GO:0002694 ! regulation of leukocyte activation is_a: GO:0050867 ! positive regulation of cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0045321 ! positively regulates leukocyte activation relationship: RO:0002213 GO:0045321 ! positively regulates leukocyte activation [Term] id: GO:0002697 name: regulation of immune effector process namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of an immune effector process." [GOC:add] is_a: GO:0002682 ! regulation of immune system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002252 ! regulates (processual) immune effector process relationship: RO:0002211 GO:0002252 ! regulates (processual) immune effector process [Term] id: GO:0002698 name: negative regulation of immune effector process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune effector process." [GOC:add] synonym: "down regulation of immune effector process" EXACT [] synonym: "down-regulation of immune effector process" EXACT [] synonym: "downregulation of immune effector process" EXACT [] is_a: GO:0002683 ! negative regulation of immune system process is_a: GO:0002697 ! regulation of immune effector process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002252 ! negatively regulates immune effector process relationship: RO:0002212 GO:0002252 ! negatively regulates immune effector process [Term] id: GO:0002699 name: positive regulation of immune effector process namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of an immune effector process." [GOC:add] synonym: "up regulation of immune effector process" EXACT [] synonym: "up-regulation of immune effector process" EXACT [] synonym: "upregulation of immune effector process" EXACT [] is_a: GO:0002684 ! positive regulation of immune system process is_a: GO:0002697 ! regulation of immune effector process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002252 ! positively regulates immune effector process relationship: RO:0002213 GO:0002252 ! positively regulates immune effector process [Term] id: GO:0002700 name: regulation of production of molecular mediator of immune response namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of the production of molecular mediator of immune response." [GOC:add] is_a: GO:0002697 ! regulation of immune effector process is_a: GO:0010468 ! regulation of gene expression intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002440 ! regulates (processual) production of molecular mediator of immune response relationship: RO:0002211 GO:0002440 ! regulates (processual) production of molecular mediator of immune response [Term] id: GO:0002701 name: negative regulation of production of molecular mediator of immune response namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of the production of molecular mediator of immune response." [GOC:add] synonym: "down regulation of production of molecular mediator of immune response" EXACT [] synonym: "down-regulation of production of molecular mediator of immune response" EXACT [] synonym: "downregulation of production of molecular mediator of immune response" EXACT [] is_a: GO:0002698 ! negative regulation of immune effector process is_a: GO:0002700 ! regulation of production of molecular mediator of immune response is_a: GO:0010629 ! negative regulation of gene expression intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002440 ! negatively regulates production of molecular mediator of immune response relationship: RO:0002212 GO:0002440 ! negatively regulates production of molecular mediator of immune response [Term] id: GO:0002702 name: positive regulation of production of molecular mediator of immune response namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of the production of molecular mediator of immune response." [GOC:add] synonym: "up regulation of production of molecular mediator of immune response" EXACT [] synonym: "up-regulation of production of molecular mediator of immune response" EXACT [] synonym: "upregulation of production of molecular mediator of immune response" EXACT [] is_a: GO:0002699 ! positive regulation of immune effector process is_a: GO:0002700 ! regulation of production of molecular mediator of immune response is_a: GO:0010628 ! positive regulation of gene expression intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002440 ! positively regulates production of molecular mediator of immune response relationship: RO:0002213 GO:0002440 ! positively regulates production of molecular mediator of immune response [Term] id: GO:0002703 name: regulation of leukocyte mediated immunity namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of leukocyte mediated immunity." [GOC:add] synonym: "regulation of immune cell mediated immunity" EXACT [] synonym: "regulation of leucocyte mediated immunity" EXACT [] is_a: GO:0002697 ! regulation of immune effector process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002443 ! regulates (processual) leukocyte mediated immunity relationship: RO:0002211 GO:0002443 ! regulates (processual) leukocyte mediated immunity [Term] id: GO:0002704 name: negative regulation of leukocyte mediated immunity namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte mediated immunity." [GOC:add] synonym: "down regulation of leukocyte mediated immunity" EXACT [] synonym: "down-regulation of leukocyte mediated immunity" EXACT [] synonym: "downregulation of leukocyte mediated immunity" EXACT [] synonym: "negative regulation of immune cell mediated immunity" EXACT [] synonym: "negative regulation of leucocyte mediated immunity" EXACT [] is_a: GO:0002698 ! negative regulation of immune effector process is_a: GO:0002703 ! regulation of leukocyte mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002443 ! negatively regulates leukocyte mediated immunity relationship: RO:0002212 GO:0002443 ! negatively regulates leukocyte mediated immunity [Term] id: GO:0002705 name: positive regulation of leukocyte mediated immunity namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of leukocyte mediated immunity." [GOC:add] synonym: "positive regulation of immune cell mediated immunity" EXACT [] synonym: "positive regulation of leucocyte mediated immunity" EXACT [] synonym: "up regulation of leukocyte mediated immunity" EXACT [] synonym: "up-regulation of leukocyte mediated immunity" EXACT [] synonym: "upregulation of leukocyte mediated immunity" EXACT [] is_a: GO:0002699 ! positive regulation of immune effector process is_a: GO:0002703 ! regulation of leukocyte mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002443 ! positively regulates leukocyte mediated immunity relationship: RO:0002213 GO:0002443 ! positively regulates leukocyte mediated immunity [Term] id: GO:0002706 name: regulation of lymphocyte mediated immunity namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of lymphocyte mediated immunity." [GOC:add] is_a: GO:0002703 ! regulation of leukocyte mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002449 ! regulates (processual) lymphocyte mediated immunity relationship: RO:0002211 GO:0002449 ! regulates (processual) lymphocyte mediated immunity [Term] id: GO:0002707 name: negative regulation of lymphocyte mediated immunity namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte mediated immunity." [GOC:add] synonym: "down regulation of lymphocyte mediated immunity" EXACT [] synonym: "down-regulation of lymphocyte mediated immunity" EXACT [] synonym: "downregulation of lymphocyte mediated immunity" EXACT [] is_a: GO:0002704 ! negative regulation of leukocyte mediated immunity is_a: GO:0002706 ! regulation of lymphocyte mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002449 ! negatively regulates lymphocyte mediated immunity relationship: RO:0002212 GO:0002449 ! negatively regulates lymphocyte mediated immunity [Term] id: GO:0002708 name: positive regulation of lymphocyte mediated immunity namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of lymphocyte mediated immunity." [GOC:add] synonym: "up regulation of lymphocyte mediated immunity" EXACT [] synonym: "up-regulation of lymphocyte mediated immunity" EXACT [] synonym: "upregulation of lymphocyte mediated immunity" EXACT [] is_a: GO:0002705 ! positive regulation of leukocyte mediated immunity is_a: GO:0002706 ! regulation of lymphocyte mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002449 ! positively regulates lymphocyte mediated immunity relationship: RO:0002213 GO:0002449 ! positively regulates lymphocyte mediated immunity [Term] id: GO:0002709 name: regulation of T cell mediated immunity namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of T cell mediated immunity." [GOC:add] synonym: "regulation of T lymphocyte mediated immunity" EXACT [] synonym: "regulation of T-cell mediated immunity" EXACT [] synonym: "regulation of T-lymphocyte mediated immunity" EXACT [] is_a: GO:0002706 ! regulation of lymphocyte mediated immunity is_a: GO:0002822 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002456 ! regulates (processual) T cell mediated immunity relationship: RO:0002211 GO:0002456 ! regulates (processual) T cell mediated immunity [Term] id: GO:0002710 name: negative regulation of T cell mediated immunity namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated immunity." [GOC:add] synonym: "down regulation of T cell mediated immunity" EXACT [] synonym: "down-regulation of T cell mediated immunity" EXACT [] synonym: "downregulation of T cell mediated immunity" EXACT [] synonym: "negative regulation of T lymphocyte mediated immunity" EXACT [] synonym: "negative regulation of T-cell mediated immunity" EXACT [] synonym: "negative regulation of T-lymphocyte mediated immunity" EXACT [] is_a: GO:0002707 ! negative regulation of lymphocyte mediated immunity is_a: GO:0002709 ! regulation of T cell mediated immunity is_a: GO:0002823 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002456 ! negatively regulates T cell mediated immunity relationship: RO:0002212 GO:0002456 ! negatively regulates T cell mediated immunity [Term] id: GO:0002711 name: positive regulation of T cell mediated immunity namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of T cell mediated immunity." [GOC:add] synonym: "positive regulation of T lymphocyte mediated immunity" EXACT [] synonym: "positive regulation of T-cell mediated immunity" EXACT [] synonym: "positive regulation of T-lymphocyte mediated immunity" EXACT [] synonym: "up regulation of T cell mediated immunity" EXACT [] synonym: "up-regulation of T cell mediated immunity" EXACT [] synonym: "upregulation of T cell mediated immunity" EXACT [] is_a: GO:0002708 ! positive regulation of lymphocyte mediated immunity is_a: GO:0002709 ! regulation of T cell mediated immunity is_a: GO:0002824 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002456 ! positively regulates T cell mediated immunity relationship: RO:0002213 GO:0002456 ! positively regulates T cell mediated immunity [Term] id: GO:0002718 name: regulation of cytokine production involved in immune response namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of cytokine production that contributes to an immune response." [GOC:add] is_a: GO:0001817 ! regulation of cytokine production is_a: GO:0002700 ! regulation of production of molecular mediator of immune response intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002367 ! regulates (processual) cytokine production involved in immune response relationship: RO:0002211 GO:0002367 ! regulates (processual) cytokine production involved in immune response [Term] id: GO:0002719 name: negative regulation of cytokine production involved in immune response namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine production contributing to an immune response." [GOC:add] synonym: "down-regulation of cytokine production during immune response" EXACT [] is_a: GO:0001818 ! negative regulation of cytokine production is_a: GO:0002701 ! negative regulation of production of molecular mediator of immune response is_a: GO:0002718 ! regulation of cytokine production involved in immune response intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002367 ! negatively regulates cytokine production involved in immune response relationship: RO:0002212 GO:0002367 ! negatively regulates cytokine production involved in immune response [Term] id: GO:0002720 name: positive regulation of cytokine production involved in immune response namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of cytokine production that contributes to an immune response." [GOC:add] is_a: GO:0001819 ! positive regulation of cytokine production is_a: GO:0002702 ! positive regulation of production of molecular mediator of immune response is_a: GO:0002718 ! regulation of cytokine production involved in immune response intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002367 ! positively regulates cytokine production involved in immune response relationship: RO:0002213 GO:0002367 ! positively regulates cytokine production involved in immune response [Term] id: GO:0002724 name: regulation of T cell cytokine production namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of T cell cytokine production." [GOC:add] synonym: "regulation of T lymphocyte cytokine production" EXACT [] synonym: "regulation of T-cell cytokine production" EXACT [] synonym: "regulation of T-lymphocyte cytokine production" EXACT [] is_a: GO:0002709 ! regulation of T cell mediated immunity is_a: GO:0002718 ! regulation of cytokine production involved in immune response intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002369 ! regulates (processual) T cell cytokine production relationship: RO:0002211 GO:0002369 ! regulates (processual) T cell cytokine production [Term] id: GO:0002725 name: negative regulation of T cell cytokine production namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell cytokine production." [GOC:add] synonym: "down regulation of T cell cytokine production" EXACT [] synonym: "down-regulation of T cell cytokine production" EXACT [] synonym: "downregulation of T cell cytokine production" EXACT [] synonym: "negative regulation of T lymphocyte cytokine production" EXACT [] synonym: "negative regulation of T-cell cytokine production" EXACT [] synonym: "negative regulation of T-lymphocyte cytokine production" EXACT [] is_a: GO:0002710 ! negative regulation of T cell mediated immunity is_a: GO:0002719 ! negative regulation of cytokine production involved in immune response is_a: GO:0002724 ! regulation of T cell cytokine production intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002369 ! negatively regulates T cell cytokine production relationship: RO:0002212 GO:0002369 ! negatively regulates T cell cytokine production [Term] id: GO:0002726 name: positive regulation of T cell cytokine production namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of T cell cytokine production." [GOC:add] synonym: "positive regulation of T lymphocyte cytokine production" EXACT [] synonym: "positive regulation of T-cell cytokine production" EXACT [] synonym: "positive regulation of T-lymphocyte cytokine production" EXACT [] synonym: "up regulation of T cell cytokine production" EXACT [] synonym: "up-regulation of T cell cytokine production" EXACT [] synonym: "upregulation of T cell cytokine production" EXACT [] is_a: GO:0002711 ! positive regulation of T cell mediated immunity is_a: GO:0002720 ! positive regulation of cytokine production involved in immune response is_a: GO:0002724 ! regulation of T cell cytokine production intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002369 ! positively regulates T cell cytokine production relationship: RO:0002213 GO:0002369 ! positively regulates T cell cytokine production [Term] id: GO:0002730 name: regulation of dendritic cell cytokine production namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of dendritic cell cytokine production." [GOC:add] is_a: GO:0002703 ! regulation of leukocyte mediated immunity is_a: GO:0002718 ! regulation of cytokine production involved in immune response intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002371 ! regulates (processual) dendritic cell cytokine production relationship: RO:0002211 GO:0002371 ! regulates (processual) dendritic cell cytokine production [Term] id: GO:0002731 name: negative regulation of dendritic cell cytokine production namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell cytokine production." [GOC:add] synonym: "down regulation of dendritic cell cytokine production" EXACT [] synonym: "down-regulation of dendritic cell cytokine production" EXACT [] synonym: "downregulation of dendritic cell cytokine production" EXACT [] is_a: GO:0002704 ! negative regulation of leukocyte mediated immunity is_a: GO:0002719 ! negative regulation of cytokine production involved in immune response is_a: GO:0002730 ! regulation of dendritic cell cytokine production intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002371 ! negatively regulates dendritic cell cytokine production relationship: RO:0002212 GO:0002371 ! negatively regulates dendritic cell cytokine production [Term] id: GO:0002732 name: positive regulation of dendritic cell cytokine production namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of dendritic cell cytokine production." [GOC:add] synonym: "up regulation of dendritic cell cytokine production" EXACT [] synonym: "up-regulation of dendritic cell cytokine production" EXACT [] synonym: "upregulation of dendritic cell cytokine production" EXACT [] is_a: GO:0002705 ! positive regulation of leukocyte mediated immunity is_a: GO:0002720 ! positive regulation of cytokine production involved in immune response is_a: GO:0002730 ! regulation of dendritic cell cytokine production intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002371 ! positively regulates dendritic cell cytokine production relationship: RO:0002213 GO:0002371 ! positively regulates dendritic cell cytokine production [Term] id: GO:0002761 name: regulation of myeloid leukocyte differentiation namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of myeloid leukocyte differentiation." [GOC:add] is_a: GO:0045637 ! regulation of myeloid cell differentiation is_a: GO:1902105 ! regulation of leukocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002573 ! regulates (processual) myeloid leukocyte differentiation relationship: RO:0002211 GO:0002573 ! regulates (processual) myeloid leukocyte differentiation [Term] id: GO:0002762 name: negative regulation of myeloid leukocyte differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte differentiation." [GOC:add] synonym: "down regulation of myeloid leukocyte differentiation" EXACT [] synonym: "down-regulation of myeloid leukocyte differentiation" EXACT [] synonym: "downregulation of myeloid leukocyte differentiation" EXACT [] is_a: GO:0002761 ! regulation of myeloid leukocyte differentiation is_a: GO:0045638 ! negative regulation of myeloid cell differentiation is_a: GO:1902106 ! negative regulation of leukocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002573 ! negatively regulates myeloid leukocyte differentiation relationship: RO:0002212 GO:0002573 ! negatively regulates myeloid leukocyte differentiation [Term] id: GO:0002763 name: positive regulation of myeloid leukocyte differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte differentiation." [GOC:add] synonym: "up regulation of myeloid leukocyte differentiation" EXACT [] synonym: "up-regulation of myeloid leukocyte differentiation" EXACT [] synonym: "upregulation of myeloid leukocyte differentiation" EXACT [] is_a: GO:0002761 ! regulation of myeloid leukocyte differentiation is_a: GO:0045639 ! positive regulation of myeloid cell differentiation is_a: GO:1902107 ! positive regulation of leukocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002573 ! positively regulates myeloid leukocyte differentiation relationship: RO:0002213 GO:0002573 ! positively regulates myeloid leukocyte differentiation [Term] id: GO:0002790 name: peptide secretion namespace: biological_process def: "The controlled release of a peptide from a cell or a tissue." [GOC:add] is_a: GO:0015833 ! peptide transport is_a: GO:0046903 ! secretion intersection_of: GO:0046903 ! secretion intersection_of: RO:0004009 CHEBI:16670 ! has primary input peptide [Term] id: GO:0002791 name: regulation of peptide secretion namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of peptide secretion." [GOC:add] is_a: GO:0051046 ! regulation of secretion is_a: GO:0090087 ! regulation of peptide transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002790 ! regulates (processual) peptide secretion relationship: RO:0002211 GO:0002790 ! regulates (processual) peptide secretion [Term] id: GO:0002792 name: negative regulation of peptide secretion namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of peptide secretion." [GOC:add] synonym: "down regulation of peptide secretion" EXACT [] synonym: "down-regulation of peptide secretion" EXACT [] synonym: "downregulation of peptide secretion" EXACT [] is_a: GO:0002791 ! regulation of peptide secretion is_a: GO:0051048 ! negative regulation of secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002790 ! negatively regulates peptide secretion relationship: RO:0002212 GO:0002790 ! negatively regulates peptide secretion [Term] id: GO:0002793 name: positive regulation of peptide secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of peptide secretion." [GOC:add] synonym: "up regulation of peptide secretion" EXACT [] synonym: "up-regulation of peptide secretion" EXACT [] synonym: "upregulation of peptide secretion" EXACT [] is_a: GO:0002791 ! regulation of peptide secretion is_a: GO:0051047 ! positive regulation of secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002790 ! positively regulates peptide secretion relationship: RO:0002213 GO:0002790 ! positively regulates peptide secretion [Term] id: GO:0002819 name: regulation of adaptive immune response namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of an adaptive immune response." [GOC:add] is_a: GO:0050776 ! regulation of immune response intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002250 ! regulates (processual) adaptive immune response relationship: RO:0002211 GO:0002250 ! regulates (processual) adaptive immune response [Term] id: GO:0002820 name: negative regulation of adaptive immune response namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response." [GOC:add] synonym: "down regulation of adaptive immune response" EXACT [] synonym: "down-regulation of adaptive immune response" EXACT [] synonym: "downregulation of adaptive immune response" EXACT [] is_a: GO:0002819 ! regulation of adaptive immune response is_a: GO:0050777 ! negative regulation of immune response intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002250 ! negatively regulates adaptive immune response relationship: RO:0002212 GO:0002250 ! negatively regulates adaptive immune response [Term] id: GO:0002821 name: positive regulation of adaptive immune response namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of an adaptive immune response." [GOC:add] synonym: "up regulation of adaptive immune response" EXACT [] synonym: "up-regulation of adaptive immune response" EXACT [] synonym: "upregulation of adaptive immune response" EXACT [] is_a: GO:0002819 ! regulation of adaptive immune response is_a: GO:0050778 ! positive regulation of immune response intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002250 ! positively regulates adaptive immune response relationship: RO:0002213 GO:0002250 ! positively regulates adaptive immune response [Term] id: GO:0002822 name: regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata." [GOC:add, GOC:mtg_sensu] is_a: GO:0002819 ! regulation of adaptive immune response intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002460 ! regulates (processual) adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains relationship: RO:0002160 NCBITaxon:7776 ! only in taxon Gnathostomata relationship: RO:0002162 NCBITaxon:7776 {all_only="true"} ! in taxon Gnathostomata relationship: RO:0002211 GO:0002460 ! regulates (processual) adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [Term] id: GO:0002823 name: negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata." [GOC:add, GOC:mtg_sensu] is_a: GO:0002820 ! negative regulation of adaptive immune response is_a: GO:0002822 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002460 ! negatively regulates adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains relationship: RO:0002212 GO:0002460 ! negatively regulates adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [Term] id: GO:0002824 name: positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata." [GOC:add, GOC:mtg_sensu] is_a: GO:0002821 ! positive regulation of adaptive immune response is_a: GO:0002822 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002460 ! positively regulates adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains relationship: RO:0002213 GO:0002460 ! positively regulates adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [Term] id: GO:0002831 name: regulation of response to biotic stimulus namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of a response to biotic stimulus." [GOC:add] is_a: GO:0048583 ! regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0009607 ! regulates (processual) response to biotic stimulus relationship: RO:0002211 GO:0009607 ! regulates (processual) response to biotic stimulus [Term] id: GO:0002832 name: negative regulation of response to biotic stimulus namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to biotic stimulus." [GOC:add] synonym: "down regulation of response to biotic stimulus" EXACT [] synonym: "down-regulation of response to biotic stimulus" EXACT [] synonym: "downregulation of response to biotic stimulus" EXACT [] is_a: GO:0002831 ! regulation of response to biotic stimulus is_a: GO:0048585 ! negative regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0009607 ! negatively regulates response to biotic stimulus relationship: RO:0002212 GO:0009607 ! negatively regulates response to biotic stimulus [Term] id: GO:0002833 name: positive regulation of response to biotic stimulus namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of a response to biotic stimulus." [GOC:add] synonym: "up regulation of response to biotic stimulus" EXACT [] synonym: "up-regulation of response to biotic stimulus" EXACT [] synonym: "upregulation of response to biotic stimulus" EXACT [] is_a: GO:0002831 ! regulation of response to biotic stimulus is_a: GO:0048584 ! positive regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0009607 ! positively regulates response to biotic stimulus relationship: RO:0002213 GO:0009607 ! positively regulates response to biotic stimulus [Term] id: GO:0002886 name: regulation of myeloid leukocyte mediated immunity namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of myeloid leukocyte mediated immunity." [GOC:add] is_a: GO:0002703 ! regulation of leukocyte mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002444 ! regulates (processual) myeloid leukocyte mediated immunity relationship: RO:0002211 GO:0002444 ! regulates (processual) myeloid leukocyte mediated immunity [Term] id: GO:0002887 name: negative regulation of myeloid leukocyte mediated immunity namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte mediated immunity." [GOC:add] synonym: "down regulation of myeloid leukocyte mediated immunity" EXACT [] synonym: "down-regulation of myeloid leukocyte mediated immunity" EXACT [] synonym: "downregulation of myeloid leukocyte mediated immunity" EXACT [] is_a: GO:0002704 ! negative regulation of leukocyte mediated immunity is_a: GO:0002886 ! regulation of myeloid leukocyte mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002444 ! negatively regulates myeloid leukocyte mediated immunity relationship: RO:0002212 GO:0002444 ! negatively regulates myeloid leukocyte mediated immunity [Term] id: GO:0002888 name: positive regulation of myeloid leukocyte mediated immunity namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte mediated immunity." [GOC:add] synonym: "up regulation of myeloid leukocyte mediated immunity" EXACT [] synonym: "up-regulation of myeloid leukocyte mediated immunity" EXACT [] synonym: "upregulation of myeloid leukocyte mediated immunity" EXACT [] is_a: GO:0002705 ! positive regulation of leukocyte mediated immunity is_a: GO:0002886 ! regulation of myeloid leukocyte mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002444 ! positively regulates myeloid leukocyte mediated immunity relationship: RO:0002213 GO:0002444 ! positively regulates myeloid leukocyte mediated immunity [Term] id: GO:0002932 name: tendon sheath development namespace: biological_process def: "The process whose specific outcome is the progression of a tendon sheath over time, from its formation to the mature structure. A tendon sheath is a layer of membrane around a tendon. It permits the tendon to move." [PMID:20696843] is_a: GO:0061448 ! connective tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000304 ! results in development of tendon sheath relationship: BFO:0000050 GO:0035989 ! part of tendon development relationship: RO:0002296 UBERON:0000304 ! results in development of tendon sheath creation_date: 2012-04-23T02:11:22Z [Term] id: GO:0003002 name: regionalization namespace: biological_process def: "The pattern specification process that results in the subdivision of an axis or axes in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment." [GOC:dph, GOC:isa_complete] is_a: GO:0007389 ! pattern specification process [Term] id: GO:0003006 name: developmental process involved in reproduction namespace: biological_process def: "A developmental process in which a progressive change in the state of some part of an organism, germline or somatic, specifically contributes to its ability to form offspring." [GOC:dph, GOC:isa_complete] is_a: GO:0022414 ! reproductive process is_a: GO:0032502 ! developmental process intersection_of: GO:0032502 ! developmental process intersection_of: BFO:0000050 GO:0000003 ! part of reproduction [Term] id: GO:0003007 name: heart morphogenesis namespace: biological_process def: "The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood." [GOC:dph, GOC:isa_complete] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0007100 ! results in morphogenesis of primary circulatory organ relationship: BFO:0000050 GO:0007507 ! part of heart development relationship: RO:0002298 UBERON:0007100 ! results in morphogenesis of primary circulatory organ [Term] id: GO:0003008 name: system process namespace: biological_process def: "A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective." [GOC:mtg_cardio] synonym: "organ system process" EXACT [] is_a: GO:0032501 ! multicellular organismal process [Term] id: GO:0003009 name: skeletal muscle contraction namespace: biological_process def: "A process in which force is generated within skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and in most cases it is under voluntary control." [GOC:mtg_cardio, GOC:mtg_muscle] is_a: GO:0006941 ! striated muscle contraction intersection_of: GO:0006936 ! muscle contraction intersection_of: BFO:0000066 UBERON:0001134 ! occurs in skeletal muscle tissue relationship: BFO:0000050 GO:0050881 ! part of musculoskeletal movement relationship: BFO:0000066 UBERON:0001134 ! occurs in skeletal muscle tissue [Term] id: GO:0003012 name: muscle system process namespace: biological_process def: "A organ system process carried out at the level of a muscle. Muscle tissue is composed of contractile cells or fibers." [GOC:mtg_cardio] is_a: GO:0003008 ! system process [Term] id: GO:0003013 name: circulatory system process namespace: biological_process def: "A organ system process carried out by any of the organs or tissues of the circulatory system. The circulatory system is an organ system that moves extracellular fluids to and from tissue within a multicellular organism." [GOC:mtg_cardio] xref: Wikipedia:Circulatory_system is_a: GO:0003008 ! system process [Term] id: GO:0003014 name: renal system process namespace: biological_process def: "A organ system process carried out by any of the organs or tissues of the renal system. The renal system maintains fluid balance, and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels; in other species, the renal system may comprise related structures (e.g., nephrocytes and malpighian tubules in Drosophila)." [GOC:cjm, GOC:mtg_cardio, GOC:mtg_kidney_jan10] synonym: "excretory system process" EXACT [] is_a: GO:0003008 ! system process [Term] id: GO:0003015 name: heart process namespace: biological_process def: "A circulatory system process carried out by the heart. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood." [GOC:mtg_cardio] is_a: GO:0003013 ! circulatory system process [Term] id: GO:0003016 name: respiratory system process namespace: biological_process def: "A process carried out by the organs or tissues of the respiratory system. The respiratory system is an organ system responsible for respiratory gaseous exchange." [GOC:dph, GOC:mtg_cardio, GOC:tb] synonym: "respiratory gaseous exchange" EXACT [] is_a: GO:0003008 ! system process relationship: BFO:0000050 GO:0007585 ! part of respiratory gaseous exchange by respiratory system [Term] id: GO:0003032 name: detection of oxygen namespace: biological_process def: "The series of events in which an oxygen stimulus is received by a cell and converted into a molecular signal." [GOC:mtg_cardio] is_a: GO:0009593 ! detection of chemical stimulus is_a: GO:0070482 ! response to oxygen levels [Term] id: GO:0003096 name: renal sodium ion transport namespace: biological_process def: "The directed movement of sodium ions (Na+) by the renal system." [GOC:mtg_cardio] is_a: GO:0003014 ! renal system process is_a: GO:0006814 ! sodium ion transport intersection_of: GO:0006814 ! sodium ion transport intersection_of: BFO:0000066 UBERON:0001008 ! occurs in renal system relationship: BFO:0000066 UBERON:0001008 ! occurs in renal system [Term] id: GO:0003131 name: mesodermal-endodermal cell signaling namespace: biological_process def: "Any process that mediates the transfer of information from mesodermal cells to endodermal cells." [GOC:mtg_heart] synonym: "mesodermal-endodermal cell signalling" EXACT [GOC:mah] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: RO:0002231 CL:0000222 ! has start location mesodermal cell intersection_of: RO:0002232 CL:0000223 ! has end location endodermal cell relationship: RO:0002231 CL:0000222 ! has start location mesodermal cell relationship: RO:0002232 CL:0000223 ! has end location endodermal cell creation_date: 2009-09-22T03:07:34Z [Term] id: GO:0003133 name: endodermal-mesodermal cell signaling namespace: biological_process def: "Any process that mediates the transfer of information from endodermal cells to mesodermal cells." [GOC:mtg_heart] synonym: "endodermal-mesodermal cell signalling" EXACT [GOC:mah] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: RO:0002231 CL:0000223 ! has start location endodermal cell intersection_of: RO:0002232 CL:0000222 ! has end location mesodermal cell relationship: RO:0002231 CL:0000223 ! has start location endodermal cell relationship: RO:0002232 CL:0000222 ! has end location mesodermal cell creation_date: 2009-09-22T03:10:29Z [Term] id: GO:0003142 name: cardiogenic plate morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the cardiogenic plate are generated and organized. The cardiogenic plate is the first recognizable structure derived from the heart field." [GOC:mtg_heart] synonym: "cardiac crescent morphogenesis" EXACT [GOC:mtg_heart] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0004139 ! results in morphogenesis of cardiogenic plate relationship: BFO:0000050 GO:0003007 ! part of heart morphogenesis relationship: RO:0002298 UBERON:0004139 ! results in morphogenesis of cardiogenic plate creation_date: 2009-09-22T04:12:18Z [Term] id: GO:0003143 name: embryonic heart tube morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the embryonic heart tube are generated and organized. The embryonic heart tube is an epithelial tube that will give rise to the mature heart." [GOC:mtg_heart] is_a: GO:0048598 ! embryonic morphogenesis is_a: GO:0060562 ! epithelial tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0004141 ! results in morphogenesis of heart tube relationship: BFO:0000050 GO:0003007 ! part of heart morphogenesis relationship: BFO:0000050 GO:0035050 ! part of embryonic heart tube development relationship: BFO:0000050 GO:0048562 ! part of embryonic organ morphogenesis relationship: RO:0002298 UBERON:0004141 ! results in morphogenesis of heart tube creation_date: 2009-09-22T04:21:17Z [Term] id: GO:0003144 name: embryonic heart tube formation namespace: biological_process def: "The process that gives rise to the embryonic heart tube. This process pertains to the initial formation of a structure from unspecified parts. The embryonic heart tube is an epithelial tube that will give rise to the mature heart." [GOC:mtg_heart] is_a: GO:0001838 ! embryonic epithelial tube formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0004141 ! results in formation of anatomical entity heart tube relationship: BFO:0000050 GO:0003143 ! part of embryonic heart tube morphogenesis relationship: RO:0002297 UBERON:0004141 ! results in formation of anatomical entity heart tube creation_date: 2009-09-22T04:22:34Z [Term] id: GO:0003145 name: embryonic heart tube formation via epithelial folding namespace: biological_process def: "The process that gives rise to the embryonic heart tube by the cells of the heart field along a linear axis." [GOC:mtg_heart] is_a: GO:0003144 ! embryonic heart tube formation creation_date: 2009-09-22T04:26:03Z [Term] id: GO:0003147 name: neural crest cell migration involved in heart formation namespace: biological_process def: "The characteristic movement of a cell from the dorsal ridge of the neural tube towards the heart and that contributes to heart formation." [GOC:mtg_heart] is_a: GO:0001755 ! neural crest cell migration is_a: GO:0060974 ! cell migration involved in heart formation intersection_of: GO:0001755 ! neural crest cell migration intersection_of: BFO:0000050 GO:0060914 ! part of heart formation relationship: BFO:0000050 GO:0061308 ! part of cardiac neural crest cell development involved in heart development creation_date: 2009-09-22T04:29:55Z [Term] id: GO:0003148 name: outflow tract septum morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the outflow tract septum are generated and organized. The outflow tract septum is a partition in the outflow tract." [GOC:mtg_heart] is_a: GO:0060411 ! cardiac septum morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0004142 ! results in morphogenesis of outflow tract septum relationship: BFO:0000050 GO:0003151 ! part of outflow tract morphogenesis relationship: RO:0002298 UBERON:0004142 ! results in morphogenesis of outflow tract septum creation_date: 2009-09-22T07:51:01Z [Term] id: GO:0003149 name: membranous septum morphogenesis namespace: biological_process def: "The process in which the membranous septum is generated and organized. The membranous septum is the upper part of ventricular septum." [GOC:mtg_heart] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0004666 ! results in morphogenesis of interventricular septum membranous part relationship: BFO:0000050 GO:0060412 ! part of ventricular septum morphogenesis relationship: RO:0002298 UBERON:0004666 ! results in morphogenesis of interventricular septum membranous part creation_date: 2009-09-22T07:51:41Z [Term] id: GO:0003150 name: muscular septum morphogenesis namespace: biological_process def: "The process in which the muscular septum is generated and organized. The muscular septum is the lower part of the ventricular septum." [GOC:mtg_heart] is_a: GO:0060415 ! muscle tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0004667 ! results in morphogenesis of interventricular septum muscular part relationship: BFO:0000050 GO:0060412 ! part of ventricular septum morphogenesis relationship: RO:0002298 UBERON:0004667 ! results in morphogenesis of interventricular septum muscular part creation_date: 2009-09-22T07:53:28Z [Term] id: GO:0003151 name: outflow tract morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries." [GOC:mtg_heart, UBERON:0004145] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0004145 ! results in morphogenesis of outflow tract relationship: BFO:0000050 GO:0003007 ! part of heart morphogenesis relationship: RO:0002298 UBERON:0004145 ! results in morphogenesis of outflow tract creation_date: 2009-09-22T07:59:24Z [Term] id: GO:0003152 name: morphogenesis of an epithelial fold involved in embryonic heart tube formation namespace: biological_process def: "The morphogenetic process in which an epithelial sheet bends along a linear axis, contributing to embryonic heart tube formation." [GOC:mtg_heart] is_a: GO:0048598 ! embryonic morphogenesis is_a: GO:0060571 ! morphogenesis of an epithelial fold intersection_of: GO:0060571 ! morphogenesis of an epithelial fold intersection_of: BFO:0000050 GO:0003144 ! part of embryonic heart tube formation relationship: BFO:0000050 GO:0003145 ! part of embryonic heart tube formation via epithelial folding creation_date: 2009-09-23T10:10:24Z [Term] id: GO:0003156 name: regulation of animal organ formation namespace: biological_process def: "Any process that modulates the rate, frequency or extent of animal organ formation. Organ formation is the process pertaining to the initial formation of an organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment." [GOC:dph, GOC:mtg_heart, GOC:tb] is_a: GO:2000027 ! regulation of animal organ morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048645 ! regulates (processual) animal organ formation relationship: RO:0002211 GO:0048645 ! regulates (processual) animal organ formation creation_date: 2009-09-30T11:21:09Z [Term] id: GO:0003157 name: endocardium development namespace: biological_process def: "The process whose specific outcome is the progression of the endocardium over time, from its formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers." [GOC:mtg_heart] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002165 ! results in development of endocardium relationship: BFO:0000050 GO:0007507 ! part of heart development relationship: RO:0002296 UBERON:0002165 ! results in development of endocardium creation_date: 2009-10-01T12:42:27Z [Term] id: GO:0003158 name: endothelium development namespace: biological_process def: "The process whose specific outcome is the progression of an endothelium over time, from its formation to the mature structure. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells." [GOC:mtg_heart] is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001986 ! results in development of endothelium relationship: RO:0002296 UBERON:0001986 ! results in development of endothelium creation_date: 2009-10-01T12:50:57Z [Term] id: GO:0003159 name: morphogenesis of an endothelium namespace: biological_process def: "The process in which the anatomical structure of an endothelium is generated and organized. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells." [GOC:mtg_heart] is_a: GO:0002009 ! morphogenesis of an epithelium intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001986 ! results in morphogenesis of endothelium relationship: BFO:0000050 GO:0003158 ! part of endothelium development relationship: RO:0002298 UBERON:0001986 ! results in morphogenesis of endothelium creation_date: 2009-10-01T01:34:06Z [Term] id: GO:0003160 name: endocardium morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the endocardium is generated and organized. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers." [GOC:mtg_heart] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002165 ! results in morphogenesis of endocardium relationship: BFO:0000050 GO:0003157 ! part of endocardium development relationship: RO:0002298 UBERON:0002165 ! results in morphogenesis of endocardium creation_date: 2009-10-01T01:37:26Z [Term] id: GO:0003161 name: cardiac conduction system development namespace: biological_process def: "The process whose specific outcome is the progression of the cardiac conduction system over time, from its formation to the mature structure. The cardiac conduction system consists of specialized cardiomyocytes that regulate the frequency of heart beat." [GOC:mtg_heart] synonym: "cardiac impulse conducting system development" EXACT [GOC:mtg_heart] synonym: "heart conduction system development" EXACT [GOC:mtg_heart] is_a: GO:0048738 ! cardiac muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002350 ! results in development of conducting system of heart relationship: RO:0002296 UBERON:0002350 ! results in development of conducting system of heart creation_date: 2009-10-01T01:57:16Z [Term] id: GO:0003162 name: atrioventricular node development namespace: biological_process def: "The process whose specific outcome is the progression of the atrioventricular (AV) node over time, from its formation to the mature structure. The AV node is part of the cardiac conduction system that controls the timing of ventricle contraction by receiving electrical signals from the sinoatrial (SA) node and relaying them to the His-Purkinje system." [GOC:mtg_heart] synonym: "AV node development" EXACT [GOC:mtg_heart] is_a: GO:0048738 ! cardiac muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002352 ! results in development of atrioventricular node relationship: BFO:0000050 GO:0003161 ! part of cardiac conduction system development relationship: RO:0002296 UBERON:0002352 ! results in development of atrioventricular node creation_date: 2009-10-01T02:05:13Z [Term] id: GO:0003163 name: sinoatrial node development namespace: biological_process def: "The process whose specific outcome is the progression of the sinoatrial (SA) node over time, from its formation to the mature structure. The SA node is part of the cardiac conduction system that controls the timing of heart muscle contraction. It relays electrical signals to the AV node." [GOC:mtg_heart] synonym: "SA node development" EXACT [GOC:mtg_heart] synonym: "SAN development" EXACT [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] is_a: GO:0003228 ! atrial cardiac muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002351 ! results in development of sinoatrial node relationship: BFO:0000050 GO:0003161 ! part of cardiac conduction system development relationship: RO:0002296 UBERON:0002351 ! results in development of sinoatrial node creation_date: 2009-10-01T02:06:09Z [Term] id: GO:0003164 name: His-Purkinje system development namespace: biological_process def: "The process whose specific outcome is the progression of the His-Purkinje system over time, from its formation to the mature structure. The His-Purkinje system receives signals from the AV node and is composed of the fibers that regulate cardiac muscle contraction in the ventricles." [GOC:mtg_heart] is_a: GO:0003229 ! ventricular cardiac muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004146 ! results in development of His-Purkinje system relationship: BFO:0000050 GO:0003161 ! part of cardiac conduction system development relationship: RO:0002296 UBERON:0004146 ! results in development of His-Purkinje system creation_date: 2009-10-01T02:07:12Z [Term] id: GO:0003165 name: Purkinje myocyte development namespace: biological_process def: "The process whose specific outcome is the progression of a Purkinje myocyte over time, from its formation to the mature structure. The Purkinje myocyte (also known as cardiac Purkinje fiber) is part of the cardiac conduction system that receives signals from the bundle of His and innervates the ventricular cardiac muscle." [GOC:mtg_cardiac_conduct_nov11, GOC:mtg_heart] synonym: "cardiac Purkinje fiber development" EXACT [] is_a: GO:0003229 ! ventricular cardiac muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002354 ! results in development of cardiac Purkinje fiber relationship: BFO:0000050 GO:0003164 ! part of His-Purkinje system development relationship: RO:0002296 UBERON:0002354 ! results in development of cardiac Purkinje fiber creation_date: 2009-10-01T02:07:50Z [Term] id: GO:0003168 name: Purkinje myocyte differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a Purkinje myocyte (also known as cardiac Purkinje fiber cell). These cells are specialized cardiomyocytes that receive signals from the bundle of His and innervate the ventricular cardiac muscle." [GOC:mtg_cardiac_conduct_nov11, GOC:mtg_heart] synonym: "cardiac Purkinje fiber cell differentiation" EXACT [] is_a: GO:0060932 ! His-Purkinje system cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0002068 ! results in acquisition of features of Purkinje myocyte relationship: BFO:0000050 GO:0003165 ! part of Purkinje myocyte development relationship: RO:0002315 CL:0002068 ! results in acquisition of features of Purkinje myocyte creation_date: 2009-10-01T02:49:54Z [Term] id: GO:0003169 name: coronary vein morphogenesis namespace: biological_process def: "The process in which the anatomical structures of veins of the heart are generated and organized." [GOC:mtg_heart] is_a: GO:0048845 ! venous blood vessel morphogenesis is_a: GO:0060977 ! coronary vasculature morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0004148 ! results in morphogenesis of cardiac vein relationship: RO:0002298 UBERON:0004148 ! results in morphogenesis of cardiac vein creation_date: 2009-10-08T10:45:41Z [Term] id: GO:0003197 name: endocardial cushion development namespace: biological_process def: "The progression of a cardiac cushion over time, from its initial formation to the mature structure. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves." [GOC:mtg_heart] is_a: GO:0060485 ! mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002062 ! results in development of endocardial cushion relationship: BFO:0000050 GO:0007507 ! part of heart development relationship: RO:0002296 UBERON:0002062 ! results in development of endocardial cushion creation_date: 2009-10-08T01:17:43Z [Term] id: GO:0003203 name: endocardial cushion morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the endocardial cushion is generated and organized. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves." [GOC:mtg_heart] is_a: GO:0072132 ! mesenchyme morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002062 ! results in morphogenesis of endocardial cushion relationship: BFO:0000050 GO:0003007 ! part of heart morphogenesis relationship: BFO:0000050 GO:0003197 ! part of endocardial cushion development relationship: RO:0002298 UBERON:0002062 ! results in morphogenesis of endocardial cushion creation_date: 2009-10-08T01:43:22Z [Term] id: GO:0003204 name: cardiac skeleton development namespace: biological_process def: "The progression of the cardiac skeleton over time, from its formation to the mature structure. The cardiac skeleton is a specialized extracellular matrix that separates the atria from the ventricles and provides physical support for the heart." [GOC:mtg_heart] synonym: "heart fibrous skeleton development" EXACT [GOC:mtg_heart] is_a: GO:0061448 ! connective tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004292 ! results in development of cardiac skeleton relationship: BFO:0000050 GO:0007507 ! part of heart development relationship: RO:0002296 UBERON:0004292 ! results in development of cardiac skeleton creation_date: 2009-10-13T09:05:04Z [Term] id: GO:0003205 name: cardiac chamber development namespace: biological_process def: "The progression of a cardiac chamber over time, from its formation to the mature structure. A cardiac chamber is an enclosed cavity within the heart." [GOC:mtg_heart] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004151 ! results in development of cardiac chamber relationship: BFO:0000050 GO:0007507 ! part of heart development relationship: RO:0002296 UBERON:0004151 ! results in development of cardiac chamber creation_date: 2009-10-13T09:11:18Z [Term] id: GO:0003206 name: cardiac chamber morphogenesis namespace: biological_process def: "The process in which a cardiac chamber is generated and organized. A cardiac chamber is an enclosed cavity within the heart." [GOC:mtg_heart] synonym: "heart chamber morphogenesis" EXACT [GOC:mtg_heart] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0004151 ! results in morphogenesis of cardiac chamber relationship: BFO:0000050 GO:0003007 ! part of heart morphogenesis relationship: BFO:0000050 GO:0003205 ! part of cardiac chamber development relationship: RO:0002298 UBERON:0004151 ! results in morphogenesis of cardiac chamber creation_date: 2009-10-13T09:14:51Z [Term] id: GO:0003207 name: cardiac chamber formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a cardiac chamber from unspecified parts. A cardiac chamber is an enclosed cavity within the heart." [GOC:mtg_heart] synonym: "heart chamber formation" EXACT [GOC:mtg_heart] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0004151 ! results in formation of anatomical entity cardiac chamber relationship: BFO:0000050 GO:0003206 ! part of cardiac chamber morphogenesis relationship: RO:0002297 UBERON:0004151 ! results in formation of anatomical entity cardiac chamber creation_date: 2009-10-13T09:29:13Z [Term] id: GO:0003208 name: cardiac ventricle morphogenesis namespace: biological_process def: "The process in which the cardiac ventricle is generated and organized. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart." [GOC:mtg_heart] is_a: GO:0003206 ! cardiac chamber morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002082 ! results in morphogenesis of cardiac ventricle relationship: BFO:0000050 GO:0003231 ! part of cardiac ventricle development relationship: RO:0002298 UBERON:0002082 ! results in morphogenesis of cardiac ventricle creation_date: 2009-10-13T09:38:44Z [Term] id: GO:0003209 name: cardiac atrium morphogenesis namespace: biological_process def: "The process in which the cardiac atrium is generated and organized. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle." [GOC:mtg_heart] is_a: GO:0003206 ! cardiac chamber morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002081 ! results in morphogenesis of cardiac atrium relationship: BFO:0000050 GO:0003230 ! part of cardiac atrium development relationship: RO:0002298 UBERON:0002081 ! results in morphogenesis of cardiac atrium creation_date: 2009-10-13T09:39:44Z [Term] id: GO:0003210 name: cardiac atrium formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a cardiac atrium from unspecified parts. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle." [GOC:mtg_heart] is_a: GO:0003207 ! cardiac chamber formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0002081 ! results in formation of anatomical entity cardiac atrium relationship: BFO:0000050 GO:0003209 ! part of cardiac atrium morphogenesis relationship: RO:0002297 UBERON:0002081 ! results in formation of anatomical entity cardiac atrium creation_date: 2009-10-13T09:44:25Z [Term] id: GO:0003211 name: cardiac ventricle formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a cardiac ventricle from unspecified parts. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart." [GOC:mtg_heart] is_a: GO:0003207 ! cardiac chamber formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0002082 ! results in formation of anatomical entity cardiac ventricle relationship: BFO:0000050 GO:0003208 ! part of cardiac ventricle morphogenesis relationship: RO:0002297 UBERON:0002082 ! results in formation of anatomical entity cardiac ventricle creation_date: 2009-10-13T09:46:27Z [Term] id: GO:0003212 name: cardiac left atrium morphogenesis namespace: biological_process def: "The process in which the left cardiac atrium is generated and organized." [GOC:mtg_heart] is_a: GO:0003209 ! cardiac atrium morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002079 ! results in morphogenesis of left cardiac atrium relationship: RO:0002298 UBERON:0002079 ! results in morphogenesis of left cardiac atrium creation_date: 2009-10-13T09:48:16Z [Term] id: GO:0003213 name: cardiac right atrium morphogenesis namespace: biological_process def: "The process in which the right cardiac atrium is generated and organized." [GOC:mtg_heart] is_a: GO:0003209 ! cardiac atrium morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002078 ! results in morphogenesis of right cardiac atrium relationship: RO:0002298 UBERON:0002078 ! results in morphogenesis of right cardiac atrium creation_date: 2009-10-13T09:49:03Z [Term] id: GO:0003214 name: cardiac left ventricle morphogenesis namespace: biological_process def: "The process in which the left cardiac ventricle is generated and organized." [GOC:mtg_heart] is_a: GO:0003208 ! cardiac ventricle morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002084 ! results in morphogenesis of heart left ventricle relationship: RO:0002298 UBERON:0002084 ! results in morphogenesis of heart left ventricle creation_date: 2009-10-13T09:50:08Z [Term] id: GO:0003215 name: cardiac right ventricle morphogenesis namespace: biological_process def: "The process in which the right cardiac ventricle is generated and organized." [GOC:mtg_heart] is_a: GO:0003208 ! cardiac ventricle morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002080 ! results in morphogenesis of heart right ventricle relationship: RO:0002298 UBERON:0002080 ! results in morphogenesis of heart right ventricle creation_date: 2009-10-13T09:50:57Z [Term] id: GO:0003216 name: cardiac left atrium formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a left cardiac atrium from unspecified parts." [GOC:mtg_heart] is_a: GO:0003210 ! cardiac atrium formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0002079 ! results in formation of anatomical entity left cardiac atrium relationship: BFO:0000050 GO:0003212 ! part of cardiac left atrium morphogenesis relationship: RO:0002297 UBERON:0002079 ! results in formation of anatomical entity left cardiac atrium creation_date: 2009-10-13T09:52:31Z [Term] id: GO:0003217 name: cardiac right atrium formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a cardiac right atrium from unspecified parts." [GOC:mtg_heart] is_a: GO:0003210 ! cardiac atrium formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0002078 ! results in formation of anatomical entity right cardiac atrium relationship: BFO:0000050 GO:0003213 ! part of cardiac right atrium morphogenesis relationship: RO:0002297 UBERON:0002078 ! results in formation of anatomical entity right cardiac atrium creation_date: 2009-10-13T09:53:12Z [Term] id: GO:0003218 name: cardiac left ventricle formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a left cardiac ventricle from unspecified parts." [GOC:mtg_heart] is_a: GO:0003211 ! cardiac ventricle formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0002084 ! results in formation of anatomical entity heart left ventricle relationship: BFO:0000050 GO:0003214 ! part of cardiac left ventricle morphogenesis relationship: RO:0002297 UBERON:0002084 ! results in formation of anatomical entity heart left ventricle creation_date: 2009-10-13T09:54:33Z [Term] id: GO:0003219 name: cardiac right ventricle formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a right cardiac ventricle from unspecified parts." [GOC:mtg_heart] is_a: GO:0003211 ! cardiac ventricle formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0002080 ! results in formation of anatomical entity heart right ventricle relationship: BFO:0000050 GO:0003215 ! part of cardiac right ventricle morphogenesis relationship: RO:0002297 UBERON:0002080 ! results in formation of anatomical entity heart right ventricle creation_date: 2009-10-13T09:55:38Z [Term] id: GO:0003220 name: left ventricular cardiac muscle tissue morphogenesis namespace: biological_process def: "The process in which the anatomical structures of left cardiac ventricle muscle are generated and organized." [GOC:mtg_heart] synonym: "left ventricular myocardium morphogenesis" EXACT [GOC:mtg_heart] is_a: GO:0055010 ! ventricular cardiac muscle tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003382 ! results in morphogenesis of cardiac muscle of left ventricle relationship: BFO:0000050 GO:0003214 ! part of cardiac left ventricle morphogenesis relationship: RO:0002298 UBERON:0003382 ! results in morphogenesis of cardiac muscle of left ventricle creation_date: 2009-10-13T10:18:05Z [Term] id: GO:0003221 name: right ventricular cardiac muscle tissue morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the right cardiac ventricle muscle are generated and organized." [GOC:mtg_heart] synonym: "right ventricle myocardium morphogenesis" EXACT [GOC:mtg_heart] is_a: GO:0055010 ! ventricular cardiac muscle tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003381 ! results in morphogenesis of cardiac muscle of right ventricle relationship: BFO:0000050 GO:0003215 ! part of cardiac right ventricle morphogenesis relationship: RO:0002298 UBERON:0003381 ! results in morphogenesis of cardiac muscle of right ventricle creation_date: 2009-10-13T10:26:33Z [Term] id: GO:0003222 name: ventricular trabecula myocardium morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the trabecular cardiac ventricle muscle are generated and organized." [GOC:mtg_heart] is_a: GO:0055010 ! ventricular cardiac muscle tissue morphogenesis is_a: GO:0061384 ! heart trabecula morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0004126 ! results in morphogenesis of trabecular layer of ventricle relationship: RO:0002298 UBERON:0004126 ! results in morphogenesis of trabecular layer of ventricle creation_date: 2009-10-13T10:33:00Z [Term] id: GO:0003225 name: left ventricular trabecular myocardium morphogenesis namespace: biological_process def: "The process in which the anatomical structures of cardiac left ventricular trabecular myocardium are generated and organized." [GOC:mtg_heart] is_a: GO:0003220 ! left ventricular cardiac muscle tissue morphogenesis is_a: GO:0003222 ! ventricular trabecula myocardium morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0005064 ! results in morphogenesis of left ventricular trabecular myocardium relationship: RO:0002298 UBERON:0005064 ! results in morphogenesis of left ventricular trabecular myocardium creation_date: 2009-10-13T10:45:09Z [Term] id: GO:0003227 name: right ventricular trabecular myocardium morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the right ventricular myocardium are generated and organized." [GOC:mtg_heart] is_a: GO:0003221 ! right ventricular cardiac muscle tissue morphogenesis is_a: GO:0003222 ! ventricular trabecula myocardium morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0005066 ! results in morphogenesis of right ventricular trabecular myocardium relationship: RO:0002298 UBERON:0005066 ! results in morphogenesis of right ventricular trabecular myocardium creation_date: 2009-10-13T10:50:59Z [Term] id: GO:0003228 name: atrial cardiac muscle tissue development namespace: biological_process def: "The process whose specific outcome is the progression of cardiac muscle of the atrium over time, from its formation to the mature structure." [GOC:mtg_heart] synonym: "atrial myocardium development" EXACT [GOC:mtg_heart] is_a: GO:0048738 ! cardiac muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004490 ! results in development of cardiac muscle tissue of atrium relationship: RO:0002296 UBERON:0004490 ! results in development of cardiac muscle tissue of atrium creation_date: 2009-10-13T10:53:18Z [Term] id: GO:0003229 name: ventricular cardiac muscle tissue development namespace: biological_process def: "The process whose specific outcome is the progression of ventricular cardiac muscle over time, from its formation to the mature structure." [GOC:mtg_heart] synonym: "ventricular myocardium development" EXACT [GOC:mtg_heart] is_a: GO:0048738 ! cardiac muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0018649 ! results in development of cardiac muscle tissue of ventricle relationship: RO:0002296 UBERON:0018649 ! results in development of cardiac muscle tissue of ventricle creation_date: 2009-10-13T10:56:01Z [Term] id: GO:0003230 name: cardiac atrium development namespace: biological_process def: "The process whose specific outcome is the progression of a cardiac atrium over time, from its formation to the mature structure. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle." [GOC:mtg_heart] is_a: GO:0003205 ! cardiac chamber development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002081 ! results in development of cardiac atrium relationship: RO:0002296 UBERON:0002081 ! results in development of cardiac atrium creation_date: 2009-10-13T11:02:07Z [Term] id: GO:0003231 name: cardiac ventricle development namespace: biological_process def: "The process whose specific outcome is the progression of a cardiac ventricle over time, from its formation to the mature structure. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart." [GOC:mtg_heart] is_a: GO:0003205 ! cardiac chamber development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002082 ! results in development of cardiac ventricle relationship: RO:0002296 UBERON:0002082 ! results in development of cardiac ventricle creation_date: 2009-10-13T11:03:16Z [Term] id: GO:0003235 name: sinus venosus development namespace: biological_process def: "The progression of the sinus venosus over time, from its formation to the mature structure. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart." [GOC:mtg_heart] is_a: GO:0003205 ! cardiac chamber development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002063 ! results in development of sinus venosus relationship: RO:0002296 UBERON:0002063 ! results in development of sinus venosus creation_date: 2009-10-13T11:12:34Z [Term] id: GO:0003236 name: sinus venosus morphogenesis namespace: biological_process def: "The process in which the sinus venosus is generated and organized. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart." [GOC:mtg_heart] is_a: GO:0003206 ! cardiac chamber morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002063 ! results in morphogenesis of sinus venosus relationship: BFO:0000050 GO:0003235 ! part of sinus venosus development relationship: RO:0002298 UBERON:0002063 ! results in morphogenesis of sinus venosus creation_date: 2009-10-13T11:16:52Z [Term] id: GO:0003237 name: sinus venosus formation namespace: biological_process def: "The developmental process pertaining to the initial formation of the sinus venosus from unspecified parts. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart." [GOC:mtg_heart] is_a: GO:0003207 ! cardiac chamber formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0002063 ! results in formation of anatomical entity sinus venosus relationship: BFO:0000050 GO:0003236 ! part of sinus venosus morphogenesis relationship: RO:0002297 UBERON:0002063 ! results in formation of anatomical entity sinus venosus creation_date: 2009-10-13T11:18:34Z [Term] id: GO:0003238 name: conus arteriosus development namespace: biological_process def: "The progression of the conus arteriosus over time, from its formation to the mature structure. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk." [GOC:mtg_heart] is_a: GO:0003205 ! cardiac chamber development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003983 ! results in development of conus arteriosus relationship: RO:0002296 UBERON:0003983 ! results in development of conus arteriosus creation_date: 2009-10-13T11:20:57Z [Term] id: GO:0003239 name: conus arteriosus morphogenesis namespace: biological_process def: "The process in which the conus arteriosus is generated and organized. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk." [GOC:mtg_heart] is_a: GO:0003206 ! cardiac chamber morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003983 ! results in morphogenesis of conus arteriosus relationship: BFO:0000050 GO:0003238 ! part of conus arteriosus development relationship: RO:0002298 UBERON:0003983 ! results in morphogenesis of conus arteriosus creation_date: 2009-10-13T11:25:04Z [Term] id: GO:0003240 name: conus arteriosus formation namespace: biological_process def: "The developmental process pertaining to the initial formation of the conus arteriosus from unspecified parts. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk." [GOC:mtg_heart] is_a: GO:0003207 ! cardiac chamber formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0003983 ! results in formation of anatomical entity conus arteriosus relationship: BFO:0000050 GO:0003239 ! part of conus arteriosus morphogenesis relationship: RO:0002297 UBERON:0003983 ! results in formation of anatomical entity conus arteriosus creation_date: 2009-10-13T11:25:47Z [Term] id: GO:0003241 name: growth involved in heart morphogenesis namespace: biological_process def: "Developmental growth that contributes to the shaping of the heart." [GOC:mtg_heart] is_a: GO:0060560 ! developmental growth involved in morphogenesis intersection_of: GO:0040007 ! growth intersection_of: BFO:0000050 GO:0003007 ! part of heart morphogenesis relationship: BFO:0000050 GO:0003007 ! part of heart morphogenesis relationship: BFO:0000050 GO:0060419 ! part of heart growth creation_date: 2009-10-13T11:28:46Z [Term] id: GO:0003245 name: cardiac muscle tissue growth involved in heart morphogenesis namespace: biological_process def: "The developmental growth of cardiac muscle tissue that contributes to the shaping of the heart." [GOC:mtg_heart] is_a: GO:0003241 ! growth involved in heart morphogenesis is_a: GO:0055017 ! cardiac muscle tissue growth intersection_of: GO:0055017 ! cardiac muscle tissue growth intersection_of: BFO:0000050 GO:0003007 ! part of heart morphogenesis relationship: BFO:0000050 GO:0055008 ! part of cardiac muscle tissue morphogenesis creation_date: 2009-10-13T11:44:21Z [Term] id: GO:0003248 name: heart capillary growth namespace: biological_process def: "The increase in heart capillaries that accompanies physiological hypertrophy of cardiac muscle." [GOC:mtg_heart] is_a: GO:0048589 ! developmental growth intersection_of: GO:0048589 ! developmental growth intersection_of: RO:0002343 UBERON:0006966 ! results in growth of coronary capillary relationship: BFO:0000050 GO:0060419 ! part of heart growth relationship: BFO:0000050 GO:0060976 ! part of coronary vasculature development relationship: RO:0002343 UBERON:0006966 ! results in growth of coronary capillary creation_date: 2009-10-13T11:53:12Z [Term] id: GO:0003253 name: cardiac neural crest cell migration involved in outflow tract morphogenesis namespace: biological_process def: "The orderly movement of a neural crest cell from one site to another that will contribute to the morphogenesis of the outflow tract." [GOC:mtg_heart] is_a: GO:0001755 ! neural crest cell migration is_a: GO:0060973 ! cell migration involved in heart development intersection_of: GO:0001755 ! neural crest cell migration intersection_of: BFO:0000050 GO:0003151 ! part of outflow tract morphogenesis relationship: BFO:0000050 GO:0061309 ! part of cardiac neural crest cell development involved in outflow tract morphogenesis creation_date: 2009-10-13T02:14:16Z [Term] id: GO:0003260 name: cardioblast migration namespace: biological_process def: "The orderly movement of a cardiac progenitor cell to form the heart field. Cardiac progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into cells of the heart. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:mtg_heart] is_a: GO:0060974 ! cell migration involved in heart formation intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0002664 ! results in movement of cardioblast relationship: RO:0002565 CL:0002664 ! results in movement of cardioblast creation_date: 2009-10-15T01:52:25Z [Term] id: GO:0003272 name: endocardial cushion formation namespace: biological_process def: "The developmental process pertaining to the initial formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves." [GOC:mtg_heart, PMID:15797462] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0002062 ! results in formation of anatomical entity endocardial cushion relationship: BFO:0000050 GO:0003203 ! part of endocardial cushion morphogenesis relationship: RO:0002297 UBERON:0002062 ! results in formation of anatomical entity endocardial cushion creation_date: 2009-10-20T08:53:19Z [Term] id: GO:0003273 name: cell migration involved in endocardial cushion formation namespace: biological_process def: "The orderly movement of a cell from one site to another that will contribute to the formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves." [GOC:mtg_heart] is_a: GO:0060973 ! cell migration involved in heart development intersection_of: GO:0016477 ! cell migration intersection_of: BFO:0000050 GO:0003272 ! part of endocardial cushion formation relationship: BFO:0000050 GO:0003272 ! part of endocardial cushion formation creation_date: 2009-10-20T09:08:44Z [Term] id: GO:0003275 name: apoptotic process involved in outflow tract morphogenesis namespace: biological_process def: "Any apoptotic process that contributes to the shaping of the outflow tract. The outflow tract is the portion of the heart through which blood flows into the arteries." [GOC:mtg_apoptosis, GOC:mtg_heart] is_a: GO:0003278 ! apoptotic process involved in heart morphogenesis intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000050 GO:0003151 ! part of outflow tract morphogenesis relationship: BFO:0000050 GO:0003151 ! part of outflow tract morphogenesis creation_date: 2009-10-20T09:30:01Z [Term] id: GO:0003277 name: apoptotic process involved in endocardial cushion morphogenesis namespace: biological_process def: "Any apoptotic process that contributes to the shaping of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves." [GOC:mtg_apoptosis, GOC:mtg_heart] is_a: GO:0003278 ! apoptotic process involved in heart morphogenesis intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000050 GO:0003203 ! part of endocardial cushion morphogenesis relationship: BFO:0000050 GO:0003203 ! part of endocardial cushion morphogenesis creation_date: 2009-10-20T09:37:03Z [Term] id: GO:0003278 name: apoptotic process involved in heart morphogenesis namespace: biological_process def: "Any apoptotic process that contributes to the shaping of the heart." [GOC:mtg_apoptosis, GOC:mtg_heart] is_a: GO:0060561 ! apoptotic process involved in morphogenesis intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000050 GO:0003007 ! part of heart morphogenesis relationship: BFO:0000050 GO:0003007 ! part of heart morphogenesis creation_date: 2009-10-20T09:40:22Z [Term] id: GO:0003279 name: cardiac septum development namespace: biological_process def: "The progression of a cardiac septum over time, from its initial formation to the mature structure." [GOC:mtg_heart] synonym: "heart septum development" EXACT [GOC:mtg_heart] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002099 ! results in development of cardiac septum relationship: BFO:0000050 GO:0003205 ! part of cardiac chamber development relationship: RO:0002296 UBERON:0002099 ! results in development of cardiac septum creation_date: 2009-10-20T09:45:13Z [Term] id: GO:0003281 name: ventricular septum development namespace: biological_process def: "The progression of the ventricular septum over time from its formation to the mature structure." [GOC:mtg_heart] synonym: "interventricular septum development" EXACT [GOC:mtg_heart] is_a: GO:0003279 ! cardiac septum development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002094 ! results in development of interventricular septum relationship: BFO:0000050 GO:0003231 ! part of cardiac ventricle development relationship: RO:0002296 UBERON:0002094 ! results in development of interventricular septum creation_date: 2009-10-20T10:04:51Z [Term] id: GO:0003283 name: atrial septum development namespace: biological_process def: "The progression of the atrial septum over time, from its initial formation to the mature structure." [GOC:mtg_heart] is_a: GO:0003279 ! cardiac septum development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002085 ! results in development of interatrial septum relationship: BFO:0000050 GO:0003230 ! part of cardiac atrium development relationship: RO:0002296 UBERON:0002085 ! results in development of interatrial septum creation_date: 2009-10-20T10:10:38Z [Term] id: GO:0003292 name: cardiac septum cell differentiation namespace: biological_process def: "The process in which an endocardial cushion cell becomes a cell of a cardiac septum." [GOC:mtg_heart] is_a: GO:0035051 ! cardiocyte differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:2000022 ! results in acquisition of features of cardiac septum cell relationship: BFO:0000050 GO:0003279 ! part of cardiac septum development relationship: RO:0002315 CL:2000022 ! results in acquisition of features of cardiac septum cell creation_date: 2009-10-20T11:03:46Z [Term] id: GO:0003298 name: physiological muscle hypertrophy namespace: biological_process def: "The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development." [GOC:mtg_heart] is_a: GO:0014896 ! muscle hypertrophy creation_date: 2009-10-22T09:24:51Z [Term] id: GO:0003300 name: cardiac muscle hypertrophy namespace: biological_process def: "The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division." [GOC:mtg_heart] is_a: GO:0014897 ! striated muscle hypertrophy creation_date: 2009-10-22T10:33:56Z [Term] id: GO:0003301 name: physiological cardiac muscle hypertrophy namespace: biological_process def: "The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division. This process contributes to the developmental growth of the heart." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:mtg_heart] is_a: GO:0003298 ! physiological muscle hypertrophy is_a: GO:0003300 ! cardiac muscle hypertrophy relationship: BFO:0000050 GO:0055017 ! part of cardiac muscle tissue growth creation_date: 2009-10-22T10:38:10Z [Term] id: GO:0003309 name: type B pancreatic cell differentiation namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features of a type B pancreatic cell. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin." [CL:0000169, GOC:dph, PMID:11076772] synonym: "pancreatic B cell differentiation" EXACT [GOC:mah] synonym: "pancreatic beta cell differentiation" EXACT [GOC:dph] is_a: GO:0035883 ! enteroendocrine cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000169 ! results in acquisition of features of type B pancreatic cell relationship: BFO:0000050 GO:0031018 ! part of endocrine pancreas development relationship: RO:0002315 CL:0000169 ! results in acquisition of features of type B pancreatic cell creation_date: 2009-10-26T09:27:23Z [Term] id: GO:0003310 name: pancreatic A cell differentiation namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic A cell. A pancreatic A cell is a cell in the pancreas that secretes glucagon." [GOC:dph, PMID:11076772] synonym: "pancreatic alpha cell differentiation" EXACT [GOC:dph] is_a: GO:0035883 ! enteroendocrine cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000171 ! results in acquisition of features of pancreatic A cell relationship: BFO:0000050 GO:0031018 ! part of endocrine pancreas development relationship: RO:0002315 CL:0000171 ! results in acquisition of features of pancreatic A cell creation_date: 2009-10-26T09:28:05Z [Term] id: GO:0003311 name: pancreatic D cell differentiation namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and functional features that characterize a pancreatic delta cell. A delta cell is a cell of the pancreas that produces somatostatin." [GOC:dph, PMID:11076772] synonym: "pancreatic delta cell differentiation" EXACT [GOC:dph] is_a: GO:0035883 ! enteroendocrine cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000173 ! results in acquisition of features of pancreatic D cell relationship: BFO:0000050 GO:0031018 ! part of endocrine pancreas development relationship: RO:0002315 CL:0000173 ! results in acquisition of features of pancreatic D cell creation_date: 2009-10-26T09:30:27Z [Term] id: GO:0003312 name: pancreatic PP cell differentiation namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic polypeptide-producing cell. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide." [GOC:dph, PMID:11076772] synonym: "pancreatic polypeptide-producing cell differentiation" EXACT [GOC:dph] is_a: GO:0035883 ! enteroendocrine cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0002275 ! results in acquisition of features of pancreatic PP cell relationship: BFO:0000050 GO:0031018 ! part of endocrine pancreas development relationship: RO:0002315 CL:0002275 ! results in acquisition of features of pancreatic PP cell creation_date: 2009-10-26T09:32:32Z [Term] id: GO:0003313 name: heart rudiment development namespace: biological_process def: "The progression of the heart rudiment over time, from its initial formation to the mature structure. The heart rudiment is a cone-like structure that is formed when myocardial progenitor cells of the heart field fuse at the midline. The heart rudiment is the first structure of the heart tube." [GOC:mtg_heart] synonym: "heart cone development" EXACT [GOC:mtg_heart] is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004291 ! results in development of heart rudiment relationship: BFO:0000050 GO:0035050 ! part of embryonic heart tube development relationship: RO:0002296 UBERON:0004291 ! results in development of heart rudiment creation_date: 2009-10-27T08:32:40Z [Term] id: GO:0003314 name: heart rudiment morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the heart rudiment are generated and organized." [GOC:mtg_heart] synonym: "heart cone morphogenesis" EXACT [GOC:mtg_heart] is_a: GO:0002009 ! morphogenesis of an epithelium is_a: GO:0048598 ! embryonic morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0004291 ! results in morphogenesis of heart rudiment relationship: BFO:0000050 GO:0003313 ! part of heart rudiment development relationship: RO:0002298 UBERON:0004291 ! results in morphogenesis of heart rudiment creation_date: 2009-10-27T08:38:04Z [Term] id: GO:0003315 name: heart rudiment formation namespace: biological_process def: "The developmental process pertaining to the initial formation of the heart rudiment." [GOC:mtg_heart] synonym: "heart cone formation" EXACT [GOC:mtg_heart] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0004291 ! results in formation of anatomical entity heart rudiment relationship: BFO:0000050 GO:0003314 ! part of heart rudiment morphogenesis relationship: RO:0002297 UBERON:0004291 ! results in formation of anatomical entity heart rudiment creation_date: 2009-10-27T08:43:37Z [Term] id: GO:0003322 name: pancreatic A cell development namespace: biological_process def: "The process whose specific outcome is the progression of a pancreatic A cell over time, from its formation to the mature structure. A pancreatic A cell is a cell in the pancreas that secretes glucagon." [GOC:dph] synonym: "pancreatic alpha cell development" EXACT [GOC:dph] is_a: GO:0002068 ! glandular epithelial cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000171 ! results in development of pancreatic A cell relationship: BFO:0000050 GO:0003310 ! part of pancreatic A cell differentiation relationship: RO:0002296 CL:0000171 ! results in development of pancreatic A cell creation_date: 2009-11-02T08:13:55Z [Term] id: GO:0003323 name: type B pancreatic cell development namespace: biological_process def: "The process whose specific outcome is the progression of a type B pancreatic cell over time, from its formation to the mature structure. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin." [CL:0000169, GOC:dph] synonym: "pancreatic B cell development" EXACT [GOC:mah] synonym: "pancreatic beta cell development" EXACT [GOC:dph] is_a: GO:0002068 ! glandular epithelial cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000169 ! results in development of type B pancreatic cell relationship: BFO:0000050 GO:0003309 ! part of type B pancreatic cell differentiation relationship: RO:0002296 CL:0000169 ! results in development of type B pancreatic cell creation_date: 2009-11-02T08:20:11Z [Term] id: GO:0003324 name: pancreatic D cell development namespace: biological_process def: "The process whose specific outcome is the progression of a pancreatic delta cell over time, from its formation to the mature structure. A delta cell is a cell of the pancreas that produces somatostatin." [GOC:dph] synonym: "pancreatic delta cell development" EXACT [GOC:dph] is_a: GO:0002068 ! glandular epithelial cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000173 ! results in development of pancreatic D cell relationship: BFO:0000050 GO:0003311 ! part of pancreatic D cell differentiation relationship: RO:0002296 CL:0000173 ! results in development of pancreatic D cell creation_date: 2009-11-02T08:23:26Z [Term] id: GO:0003325 name: pancreatic PP cell development namespace: biological_process def: "The process whose specific outcome is the progression of a pancreatic PP cell over time, from its formation to the mature structure. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide." [GOC:dph] is_a: GO:0002068 ! glandular epithelial cell development intersection_of: GO:0048468 ! cell development intersection_of: RO:0002296 CL:0002275 ! results in development of pancreatic PP cell relationship: BFO:0000050 GO:0003312 ! part of pancreatic PP cell differentiation relationship: RO:0002296 CL:0002275 ! results in development of pancreatic PP cell creation_date: 2009-11-02T08:25:03Z [Term] id: GO:0003333 name: amino acid transmembrane transport namespace: biological_process def: "The process in which an amino acid is transported across a membrane." [GOC:dph, GOC:tb] synonym: "amino acid membrane transport" EXACT [] is_a: GO:0006865 ! amino acid transport is_a: GO:1903825 ! organic acid transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002342 GO:0016020 ! results in transport across membrane intersection_of: RO:0004009 CHEBI:33709 ! has primary input amino acid creation_date: 2009-11-02T02:36:11Z [Term] id: GO:0003337 name: mesenchymal to epithelial transition involved in metanephros morphogenesis namespace: biological_process def: "A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros." [GOC:dph, GOC:yaf] is_a: GO:0035850 ! epithelial cell differentiation involved in kidney development is_a: GO:0060231 ! mesenchymal to epithelial transition is_a: GO:0072202 ! cell differentiation involved in metanephros development intersection_of: GO:0060231 ! mesenchymal to epithelial transition intersection_of: BFO:0000050 GO:0003338 ! part of metanephros morphogenesis relationship: BFO:0000050 GO:0072283 ! part of metanephric renal vesicle morphogenesis creation_date: 2009-11-24T09:29:49Z [Term] id: GO:0003338 name: metanephros morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the metanephros are generated and organized." [GOC:dph, GOC:yaf] is_a: GO:0060993 ! kidney morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000081 ! results in morphogenesis of metanephros relationship: BFO:0000050 GO:0001656 ! part of metanephros development relationship: RO:0002298 UBERON:0000081 ! results in morphogenesis of metanephros creation_date: 2009-11-24T09:32:09Z [Term] id: GO:0003339 name: regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis namespace: biological_process def: "Any process that modulates the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros." [GOC:dph] is_a: GO:2000696 ! regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003337 ! regulates (processual) mesenchymal to epithelial transition involved in metanephros morphogenesis relationship: RO:0002211 GO:0003337 ! regulates (processual) mesenchymal to epithelial transition involved in metanephros morphogenesis creation_date: 2009-11-24T09:43:04Z [Term] id: GO:0003340 name: negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis namespace: biological_process def: "Any process that decreases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros." [GOC:dph, GOC:yaf] is_a: GO:0003339 ! regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis is_a: GO:2000697 ! negative regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0003337 ! negatively regulates mesenchymal to epithelial transition involved in metanephros morphogenesis relationship: RO:0002212 GO:0003337 ! negatively regulates mesenchymal to epithelial transition involved in metanephros morphogenesis creation_date: 2009-11-24T09:46:12Z [Term] id: GO:0003341 name: cilium movement namespace: biological_process def: "The directed, self-propelled movement of a cilium." [GOC:dph, GOC:jl] synonym: "microtubule-based flagellum movement" EXACT [] is_a: GO:0007018 ! microtubule-based movement intersection_of: GO:0007018 ! microtubule-based movement intersection_of: RO:0002565 GO:0005929 ! results in movement of cilium intersection_of: RO:0002608 GO:0005874 ! process has causal agent microtubule relationship: RO:0002160 NCBITaxon:2759 ! only in taxon Eukaryota relationship: RO:0002162 NCBITaxon:2759 {all_only="true"} ! in taxon Eukaryota relationship: RO:0002565 GO:0005929 ! results in movement of cilium creation_date: 2009-11-24T09:56:26Z [Term] id: GO:0003342 name: proepicardium development namespace: biological_process def: "The progression of the proepicardium from its formation to the mature structure. The proepicardium is an outpouching of the septum transversum." [GOC:dph, PMID:18722343] is_a: GO:0060485 ! mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004160 ! results in development of proepicardium relationship: BFO:0000050 GO:0003343 ! part of septum transversum development relationship: RO:0002296 UBERON:0004160 ! results in development of proepicardium creation_date: 2009-12-01T10:30:17Z [Term] id: GO:0003343 name: septum transversum development namespace: biological_process def: "The progression of the septum transversum from its initial formation to the mature structure. The septum transversum is a portion of the trunk mesenchyme." [GOC:dph, PMID:18722343] is_a: GO:0060485 ! mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004161 ! results in development of septum transversum relationship: RO:0002296 UBERON:0004161 ! results in development of septum transversum creation_date: 2009-12-01T10:40:17Z [Term] id: GO:0003344 name: pericardium morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the pericardium is generated and organized." [GOC:dph, PMID:18722343] is_a: GO:0002011 ! morphogenesis of an epithelial sheet is_a: GO:0048598 ! embryonic morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002407 ! results in morphogenesis of pericardium relationship: BFO:0000050 GO:0060039 ! part of pericardium development relationship: RO:0002298 UBERON:0002407 ! results in morphogenesis of pericardium creation_date: 2009-12-01T10:46:34Z [Term] id: GO:0003348 name: cardiac endothelial cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac endothelial cell." [GOC:dph, PMID:18722343] is_a: GO:0035051 ! cardiocyte differentiation is_a: GO:0045446 ! endothelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0010008 ! results in acquisition of features of cardiac endothelial cell relationship: RO:0002315 CL:0010008 ! results in acquisition of features of cardiac endothelial cell creation_date: 2009-12-01T11:12:05Z [Term] id: GO:0003352 name: regulation of cilium movement namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium." [GOC:dph] synonym: "regulation of microtubule-based flagellum movement" EXACT [] is_a: GO:0060632 ! regulation of microtubule-based movement intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003341 ! regulates (processual) cilium movement relationship: RO:0002211 GO:0003341 ! regulates (processual) cilium movement creation_date: 2009-12-03T10:12:00Z [Term] id: GO:0003353 name: positive regulation of cilium movement namespace: biological_process def: "Any process that increases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium." [GOC:dph] synonym: "positive regulation of microtubule-based flagellum movement" EXACT [] is_a: GO:0003352 ! regulation of cilium movement is_a: GO:0048522 ! positive regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0003341 ! positively regulates cilium movement relationship: RO:0002213 GO:0003341 ! positively regulates cilium movement creation_date: 2009-12-03T10:16:10Z [Term] id: GO:0003354 name: negative regulation of cilium movement namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium." [GOC:dph] synonym: "negative regulation of microtubule-based flagellum movement" EXACT [] is_a: GO:0003352 ! regulation of cilium movement is_a: GO:0048523 ! negative regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0003341 ! negatively regulates cilium movement relationship: RO:0002212 GO:0003341 ! negatively regulates cilium movement creation_date: 2009-12-03T10:17:47Z [Term] id: GO:0003357 name: noradrenergic neuron differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron, a neuron that secretes noradrenaline." [GOC:dph] synonym: "norepinephrine secreting neuron differentiation" EXACT [GOC:dph] is_a: GO:0030182 ! neuron differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0008025 ! results in acquisition of features of noradrenergic neuron relationship: RO:0002315 CL:0008025 ! results in acquisition of features of noradrenergic neuron creation_date: 2009-12-03T10:34:30Z [Term] id: GO:0003358 name: noradrenergic neuron development namespace: biological_process def: "The process whose specific outcome is the progression of a noradrenergic neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:dph] synonym: "norepinephrine secreting neuron development" EXACT [GOC:dph] is_a: GO:0048666 ! neuron development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0008025 ! results in development of noradrenergic neuron relationship: BFO:0000050 GO:0003357 ! part of noradrenergic neuron differentiation relationship: RO:0002296 CL:0008025 ! results in development of noradrenergic neuron creation_date: 2009-12-03T10:38:37Z [Term] id: GO:0003360 name: brainstem development namespace: biological_process def: "The progression of the brainstem from its formation to the mature structure. The brainstem is the part of the brain that connects the brain with the spinal cord." [GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002298 ! results in development of brainstem relationship: RO:0002296 UBERON:0002298 ! results in development of brainstem creation_date: 2009-12-03T10:47:20Z [Term] id: GO:0003361 name: noradrenergic neuron differentiation involved in brainstem development namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron that is part of the brainstem." [GOC:dph] is_a: GO:0003357 ! noradrenergic neuron differentiation intersection_of: GO:0003357 ! noradrenergic neuron differentiation intersection_of: BFO:0000050 GO:0003360 ! part of brainstem development relationship: BFO:0000050 GO:0003360 ! part of brainstem development creation_date: 2009-12-03T10:53:30Z [Term] id: GO:0003365 name: establishment of cell polarity involved in ameboidal cell migration namespace: biological_process def: "The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0030010 ! establishment of cell polarity intersection_of: GO:0030010 ! establishment of cell polarity intersection_of: BFO:0000050 GO:0001667 ! part of ameboidal-type cell migration relationship: BFO:0000050 GO:0001667 ! part of ameboidal-type cell migration creation_date: 2009-12-08T04:50:41Z [Term] id: GO:0003371 name: establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration namespace: biological_process def: "Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0030952 ! establishment or maintenance of cytoskeleton polarity intersection_of: GO:0030952 ! establishment or maintenance of cytoskeleton polarity intersection_of: BFO:0000050 GO:0001667 ! part of ameboidal-type cell migration relationship: BFO:0000050 GO:0003365 ! part of establishment of cell polarity involved in ameboidal cell migration creation_date: 2009-12-08T05:42:46Z [Term] id: GO:0003379 name: establishment of cell polarity involved in gastrulation cell migration namespace: biological_process def: "The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell taking part in gastrulation." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0003365 ! establishment of cell polarity involved in ameboidal cell migration intersection_of: GO:0030010 ! establishment of cell polarity intersection_of: BFO:0000050 GO:0042074 ! part of cell migration involved in gastrulation relationship: BFO:0000050 GO:0042074 ! part of cell migration involved in gastrulation creation_date: 2009-12-09T06:54:44Z [Term] id: GO:0003380 name: establishment or maintenance of cytoskeleton polarity involved in gastrulation namespace: biological_process def: "Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell taking part in gastrulation." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0003371 ! establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration intersection_of: GO:0030952 ! establishment or maintenance of cytoskeleton polarity intersection_of: BFO:0000050 GO:0007369 ! part of gastrulation relationship: BFO:0000050 GO:0003379 ! part of establishment of cell polarity involved in gastrulation cell migration creation_date: 2009-12-09T07:10:57Z [Term] id: GO:0003381 name: epithelial cell morphogenesis involved in gastrulation namespace: biological_process def: "The change in form that occurs when an epithelial cell progresses from it initial formation to its mature state, contributing to the process of gastrulation." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0003382 ! epithelial cell morphogenesis intersection_of: GO:0003382 ! epithelial cell morphogenesis intersection_of: BFO:0000050 GO:0007369 ! part of gastrulation relationship: BFO:0000050 GO:0007369 ! part of gastrulation creation_date: 2009-12-09T07:18:53Z [Term] id: GO:0003382 name: epithelial cell morphogenesis namespace: biological_process def: "The change in form that occurs when an epithelial cell progresses from its initial formation to its mature state." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0000902 ! cell morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002299 CL:0000066 ! results in maturation of epithelial cell relationship: BFO:0000050 GO:0002064 ! part of epithelial cell development relationship: RO:0002299 CL:0000066 ! results in maturation of epithelial cell creation_date: 2009-12-09T07:21:06Z [Term] id: GO:0003403 name: optic vesicle formation namespace: biological_process def: "The developmental process pertaining to the initial formation of the optic vesicle from the lateral wall of the forebrain. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0004128 ! results in formation of anatomical entity optic vesicle relationship: BFO:0000050 GO:0003404 ! part of optic vesicle morphogenesis relationship: BFO:0000050 GO:0060900 ! part of embryonic camera-type eye formation relationship: RO:0002297 UBERON:0004128 ! results in formation of anatomical entity optic vesicle creation_date: 2009-12-21T01:42:37Z [Term] id: GO:0003404 name: optic vesicle morphogenesis namespace: biological_process def: "The developmental process pertaining to the formation and shaping of the optic vesicle. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0048598 ! embryonic morphogenesis is_a: GO:0048729 ! tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0004128 ! results in morphogenesis of optic vesicle relationship: BFO:0000050 GO:0048596 ! part of embryonic camera-type eye morphogenesis relationship: RO:0002298 UBERON:0004128 ! results in morphogenesis of optic vesicle creation_date: 2009-12-21T01:54:34Z [Term] id: GO:0003407 name: neural retina development namespace: biological_process def: "The progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003902 ! results in development of retinal neural layer relationship: BFO:0000050 GO:0060041 ! part of retina development in camera-type eye relationship: RO:0002296 UBERON:0003902 ! results in development of retinal neural layer creation_date: 2009-12-21T02:15:14Z [Term] id: GO:0003411 name: cell motility involved in camera-type eye morphogenesis namespace: biological_process def: "Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another and contributes to the physical shaping or formation of the camera-type eye." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0048870 ! cell motility intersection_of: GO:0048870 ! cell motility intersection_of: BFO:0000050 GO:0048593 ! part of camera-type eye morphogenesis relationship: BFO:0000050 GO:0048593 ! part of camera-type eye morphogenesis creation_date: 2009-12-21T03:04:27Z [Term] id: GO:0003413 name: chondrocyte differentiation involved in endochondral bone morphogenesis namespace: biological_process def: "The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0002062 ! chondrocyte differentiation intersection_of: GO:0002062 ! chondrocyte differentiation intersection_of: BFO:0000050 GO:0060350 ! part of endochondral bone morphogenesis relationship: BFO:0000050 GO:0060351 ! part of cartilage development involved in endochondral bone morphogenesis creation_date: 2009-12-22T08:39:58Z [Term] id: GO:0003414 name: chondrocyte morphogenesis involved in endochondral bone morphogenesis namespace: biological_process def: "The process in which the structures of a chondrocyte that will contribute to bone development are generated and organized." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0090171 ! chondrocyte morphogenesis intersection_of: GO:0090171 ! chondrocyte morphogenesis intersection_of: BFO:0000050 GO:0060350 ! part of endochondral bone morphogenesis relationship: BFO:0000050 GO:0003433 ! part of chondrocyte development involved in endochondral bone morphogenesis creation_date: 2009-12-22T08:42:55Z [Term] id: GO:0003416 name: endochondral bone growth namespace: biological_process def: "The increase in size or mass of an endochondral bone that contributes to the shaping of the bone." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0098868 ! bone growth intersection_of: GO:0048589 ! developmental growth intersection_of: RO:0002343 UBERON:0002513 ! results in growth of endochondral bone relationship: RO:0002343 UBERON:0002513 ! results in growth of endochondral bone creation_date: 2009-12-22T08:52:55Z [Term] id: GO:0003433 name: chondrocyte development involved in endochondral bone morphogenesis namespace: biological_process def: "The progression of a chondrocyte over time from after its commitment to its mature state where the chondrocyte will contribute to the shaping of an endochondral bone." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0002063 ! chondrocyte development intersection_of: GO:0002063 ! chondrocyte development intersection_of: BFO:0000050 GO:0060350 ! part of endochondral bone morphogenesis relationship: BFO:0000050 GO:0003413 ! part of chondrocyte differentiation involved in endochondral bone morphogenesis creation_date: 2009-12-22T12:42:44Z [Term] id: GO:0003674 name: molecular_function namespace: molecular_function def: "A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs." [GOC:pdt] synonym: "molecular function" EXACT [] is_a: BFO:0000015 ! process disjoint_from: GO:0005575 ! cellular_component disjoint_from: GO:0008150 ! biological_process [Term] id: GO:0003824 name: catalytic activity namespace: molecular_function def: "Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic." [GOC:vw, ISBN:0198506732] synonym: "enzyme activity" EXACT [GOC:dph, GOC:tb] xref: Wikipedia:Enzyme is_a: GO:0003674 ! molecular_function [Term] id: GO:0004518 name: nuclease activity namespace: molecular_function def: "Catalysis of the hydrolysis of ester linkages within nucleic acids." [ISBN:0198547684] is_a: GO:0016788 ! hydrolase activity, acting on ester bonds [Term] id: GO:0004536 name: DNA nuclease activity namespace: molecular_function def: "Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid." [GOC:mah, ISBN:0198547684] synonym: "deoxyribonuclease activity" EXACT [] xref: Reactome:R-HSA-211247 "Cleavage of DNA by DFF40" xref: Reactome:R-HSA-5685994 "Long-range resection of DNA DSBs by EXO1 or DNA2" xref: Reactome:R-HSA-6785986 "DNA nucleases unhook the interstrand crosslink (ICL)" is_a: GO:0004518 ! nuclease activity is_a: GO:0140097 ! catalytic activity, acting on DNA relationship: BFO:0000050 GO:0006259 ! part of DNA metabolic process [Term] id: GO:0005215 name: transporter activity namespace: molecular_function def: "Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells." [GOC:ai, GOC:dgf] xref: Reactome:R-HSA-168313 "Virion-associated M2 protein mediated ion infusion" xref: Reactome:R-HSA-178215 "SMAD7:SMURF1 complex is exported to the cytosol" is_a: GO:0003674 ! molecular_function [Term] id: GO:0005275 name: amine transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of amines, including polyamines, from one side of a membrane to the other. Amines are organic compounds that are weakly basic in character and contain an amino (-NH2) or substituted amino group." [GOC:mtg_transport, ISBN:0198506732, ISBN:0815340729] synonym: "amine/polyamine transmembrane transporter activity" EXACT [] synonym: "amino acid-polyamine transmembrane transporter activity" EXACT [] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:32952 ! has primary input amine relationship: BFO:0000050 GO:0015837 ! part of amine transport relationship: RO:0004009 CHEBI:32952 ! has primary input amine [Term] id: GO:0005277 name: acetylcholine transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of acetylcholine from one side of a membrane to the other. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions." [GOC:ai] xref: Reactome:R-HSA-264615 "Loading of acetylcholine in synaptic vesicles" is_a: GO:0005326 ! neurotransmitter transmembrane transporter activity is_a: GO:0015101 ! organic cation transmembrane transporter activity is_a: GO:1901375 ! acetate ester transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:15355 ! has primary input acetylcholine relationship: RO:0004009 CHEBI:15355 ! has primary input acetylcholine [Term] id: GO:0005310 name: dicarboxylic acid transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of dicarboxylic acids from one side of a membrane to the other. A dicarboxylic acid is an organic acid with two COOH groups." [GOC:ai] xref: Reactome:R-HSA-1614546 "Sulfate is exported to the cytosol in exchange for dicarboxylate" xref: Reactome:R-HSA-372843 "SLC25A10 mediates exchange of malate and phosphate" is_a: GO:0005342 ! organic acid transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:35692 ! has primary input dicarboxylic acid relationship: BFO:0000050 GO:0006835 ! part of dicarboxylic acid transport relationship: RO:0004009 CHEBI:35692 ! has primary input dicarboxylic acid [Term] id: GO:0005319 name: lipid transporter activity namespace: molecular_function def: "Enables the directed movement of lipids into, out of or within a cell, or between cells." [GOC:ai] xref: Reactome:R-HSA-1369028 "ABCAs mediate lipid efflux" xref: Reactome:R-HSA-1369052 "ABCAs mediate lipid influx" xref: Reactome:R-HSA-174786 "ApoB-48 + 40 triacylglycerol + 60 phospholipid => ApoB-48:TG:PL complex" xref: Reactome:R-HSA-5682285 "ABCA12 transports lipids from cytosol to extracellular region" xref: Reactome:R-HSA-5682311 "Defective ABCA12 does not transport lipids from cytosol to extracellular region" xref: Reactome:R-HSA-5683672 "Defective ABCA3 does not transport PC, PG from ER membrane to lamellar body" xref: Reactome:R-HSA-5683714 "ABCA3 transports PC, PG from ER membrane to lamellar body" xref: Reactome:R-HSA-5688397 "Defective ABCA3 does not transport PC, PG from ER membrane to lamellar body" xref: Reactome:R-HSA-6801250 "TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane" xref: Reactome:R-HSA-8848053 "ABCA5 transports CHOL from lysosomal lumen to cytosol" xref: Reactome:R-HSA-8866329 "MTTP lipidates APOB-100, forming a pre-VLDL" is_a: GO:0005215 ! transporter activity intersection_of: GO:0005215 ! transporter activity intersection_of: RO:0004009 CHEBI:18059 ! has primary input lipid relationship: BFO:0000050 GO:0006869 ! part of lipid transport relationship: RO:0004009 CHEBI:18059 ! has primary input lipid [Term] id: GO:0005326 name: neurotransmitter transmembrane transporter activity namespace: molecular_function def: "Enables the directed movement of a neurotransmitter into, out of or within a cell, or between cells. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell." [GOC:ai, ISBN:0198506732] xref: Reactome:R-HSA-374896 "Uptake of Noradrenaline" xref: Reactome:R-HSA-374919 "Noradrenaline clearance from the synaptic cleft" relationship: BFO:0000050 GO:0006836 ! part of neurotransmitter transport relationship: RO:0002160 NCBITaxon:6072 ! only in taxon Eumetazoa relationship: RO:0002162 NCBITaxon:6072 {all_only="true"} ! in taxon Eumetazoa [Term] id: GO:0005342 name: organic acid transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of organic acids from one side of a membrane to the other. Organic acids are acidic compound containing carbon in covalent linkage." [ISBN:0198506732] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:64709 ! has primary input organic acid relationship: BFO:0000050 GO:1903825 ! part of organic acid transmembrane transport relationship: RO:0004009 CHEBI:64709 ! has primary input organic acid [Term] id: GO:0005355 name: glucose transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of the hexose monosaccharide glucose from one side of a membrane to the other." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] synonym: "glucose permease activity" EXACT [] xref: Reactome:R-HSA-499981 "Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2" xref: Reactome:R-HSA-5653873 "SLC2A1 tetramer transports Glc from cytosol to Golgi lumen" is_a: GO:0015149 ! hexose transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:17234 ! has primary input glucose relationship: BFO:0000050 GO:1904659 ! part of glucose transmembrane transport relationship: RO:0004009 CHEBI:17234 ! has primary input glucose [Term] id: GO:0005575 name: cellular_component namespace: cellular_component def: "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex)." [GOC:pdt] synonym: "cell or subcellular entity" EXACT [] synonym: "cellular component" EXACT [] xref: NIF_Subcellular:sao1337158144 is_a: BFO:0000040 ! material entity disjoint_from: GO:0008150 ! biological_process [Term] id: GO:0005576 name: extracellular region namespace: cellular_component def: "The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite." [GOC:go_curators] synonym: "extracellular" EXACT [] xref: Wikipedia:Extracellular is_a: GO:0110165 ! cellular anatomical entity [Term] id: GO:0005577 name: fibrinogen complex namespace: cellular_component def: "A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (alpha, beta, and gamma) linked together by disulfide bonds." [ISBN:0198547684] synonym: "fibrinogen" EXACT [] is_a: GO:0032991 ! protein-containing complex relationship: BFO:0000050 GO:0005615 ! part of extracellular space [Term] id: GO:0005581 name: collagen trimer namespace: cellular_component def: "A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures." [GOC:dos, GOC:mah, ISBN:0721639976, PMID:19693541, PMID:21421911] xref: Wikipedia:Collagen is_a: GO:0032991 ! protein-containing complex relationship: RO:0002160 NCBITaxon:33208 {source="PMID:12382326"} ! only in taxon Metazoa relationship: RO:0002162 NCBITaxon:33208 {all_only="true", source="PMID:12382326"} ! in taxon Metazoa [Term] id: GO:0005583 name: fibrillar collagen trimer namespace: cellular_component def: "Any triple helical collagen trimer that forms fibrils." [GOC:mah, ISBN:0721639976, PMID:21421911] is_a: GO:0005581 ! collagen trimer intersection_of: GO:0005581 ! collagen trimer intersection_of: BFO:0000050 GO:0098643 ! part of banded collagen fibril disjoint_from: GO:0030936 ! transmembrane collagen trimer relationship: BFO:0000050 GO:0098643 ! part of banded collagen fibril [Term] id: GO:0005587 name: collagen type IV trimer namespace: cellular_component def: "A collagen heterotrimer containing type IV alpha chains; [alpha1(IV)]2alpha2(IV) trimers are commonly observed, although more type IV alpha chains exist and may be present in type IV trimers; type IV collagen triple helices associate to form 3 dimensional nets within basement membranes." [ISBN:0721639976, PMID:19693541, PMID:21421911] xref: Wikipedia:Collagen_type_IV is_a: GO:0098642 ! network-forming collagen trimer is_a: GO:0098651 ! basement membrane collagen trimer [Term] id: GO:0005604 name: basement membrane namespace: cellular_component def: "A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers." [ISBN:0198547684, PMID:22505934] xref: Wikipedia:Basement_membrane is_a: GO:0062023 ! collagen-containing extracellular matrix [Term] id: GO:0005615 name: extracellular space namespace: cellular_component def: "That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid." [ISBN:0198547684] xref: NIF_Subcellular:sao1425028079 is_a: GO:0110165 ! cellular anatomical entity relationship: BFO:0000050 GO:0005576 ! part of extracellular region [Term] id: GO:0005622 name: intracellular anatomical structure namespace: cellular_component def: "A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm." [ISBN:0198506732] synonym: "internal to cell" EXACT [] synonym: "intracellular" EXACT [] synonym: "protoplasm" EXACT [] xref: Wikipedia:Intracellular is_a: GO:0110165 ! cellular anatomical entity relationship: BFO:0000050 CL:0000000 ! part of cell [Term] id: GO:0005634 name: nucleus namespace: cellular_component def: "A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent." [GOC:go_curators] synonym: "cell nucleus" EXACT [] xref: NIF_Subcellular:sao1702920020 xref: Wikipedia:Cell_nucleus is_a: GO:0043231 ! intracellular membrane-bounded organelle disjoint_from: GO:0005737 ! cytoplasm relationship: RO:0002160 NCBITaxon:2759 ! only in taxon Eukaryota relationship: RO:0002162 NCBITaxon:2759 {all_only="true"} ! in taxon Eukaryota [Term] id: GO:0005635 name: nuclear envelope namespace: cellular_component def: "The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space)." [ISBN:0198547684] xref: Wikipedia:Nuclear_envelope is_a: GO:0031967 ! organelle envelope relationship: BFO:0000050 GO:0005634 ! part of nucleus relationship: BFO:0000050 GO:0012505 ! part of endomembrane system [Term] id: GO:0005640 name: nuclear outer membrane namespace: cellular_component def: "The outer, i.e. cytoplasm-facing, lipid bilayer of the nuclear envelope; continuous with the endoplasmic reticulum of the cell and sometimes studded with ribosomes." [ISBN:0198547684] synonym: "nucleus outer envelope" EXACT [] synonym: "perinuclear membrane" EXACT [] xref: NIF_Subcellular:sao1617136075 is_a: GO:0031965 ! nuclear membrane is_a: GO:0031968 ! organelle outer membrane intersection_of: GO:0016020 ! membrane intersection_of: RO:0002007 GO:0005634 ! bounding layer of nucleus relationship: BFO:0000050 GO:0042175 ! part of nuclear outer membrane-endoplasmic reticulum membrane network relationship: RO:0002007 GO:0005634 ! bounding layer of nucleus [Term] id: GO:0005694 name: chromosome namespace: cellular_component def: "A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information." [ISBN:0198547684] xref: Wikipedia:Chromosome is_a: GO:0043232 ! intracellular non-membrane-bounded organelle [Term] id: GO:0005730 name: nucleolus namespace: cellular_component def: "A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome." [ISBN:0198506732] xref: NIF_Subcellular:sao1820400233 xref: Wikipedia:Nucleolus is_a: GO:0043232 ! intracellular non-membrane-bounded organelle relationship: BFO:0000050 GO:0031981 ! part of nuclear lumen [Term] id: GO:0005737 name: cytoplasm namespace: cellular_component def: "The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." [ISBN:0198547684] xref: Wikipedia:Cytoplasm is_a: GO:0110165 ! cellular anatomical entity relationship: BFO:0000050 GO:0005622 ! part of intracellular anatomical structure [Term] id: GO:0005773 name: vacuole namespace: cellular_component def: "A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol." [GOC:mtg_sensu, ISBN:0198506732] xref: Wikipedia:Vacuole is_a: GO:0043231 ! intracellular membrane-bounded organelle relationship: BFO:0000050 GO:0005737 ! part of cytoplasm [Term] id: GO:0005774 name: vacuolar membrane namespace: cellular_component def: "The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell." [GOC:ai] is_a: GO:0098588 ! bounding membrane of organelle intersection_of: GO:0016020 ! membrane intersection_of: RO:0002007 GO:0005773 ! bounding layer of vacuole relationship: RO:0002007 GO:0005773 ! bounding layer of vacuole [Term] id: GO:0005775 name: vacuolar lumen namespace: cellular_component def: "The volume enclosed within the vacuolar membrane." [ISBN:0198506732] is_a: GO:0070013 ! intracellular organelle lumen intersection_of: GO:0031974 ! membrane-enclosed lumen intersection_of: BFO:0000050 GO:0005773 ! part of vacuole relationship: BFO:0000050 GO:0005773 ! part of vacuole [Term] id: GO:0005794 name: Golgi apparatus namespace: cellular_component def: "A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways." [ISBN:0198506732] synonym: "Golgi complex" EXACT [] xref: NIF_Subcellular:sao451912436 xref: Wikipedia:Golgi_apparatus is_a: GO:0043231 ! intracellular membrane-bounded organelle relationship: BFO:0000050 GO:0005737 ! part of cytoplasm relationship: BFO:0000050 GO:0012505 ! part of endomembrane system relationship: RO:0002160 NCBITaxon:2759 ! only in taxon Eukaryota relationship: RO:0002162 NCBITaxon:2759 {all_only="true"} ! in taxon Eukaryota [Term] id: GO:0005798 name: Golgi-associated vesicle namespace: cellular_component def: "Any vesicle associated with the Golgi complex and involved in mediating transport within the Golgi or between the Golgi and other parts of the cell." [GOC:mah] xref: NIF_Subcellular:sao819927218 is_a: GO:0031410 ! cytoplasmic vesicle [Term] id: GO:0005840 name: ribosome namespace: cellular_component def: "An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins." [ISBN:0198506732] xref: NIF_Subcellular:sao1429207766 xref: Wikipedia:Ribosome is_a: GO:0043232 ! intracellular non-membrane-bounded organelle is_a: PR:000050567 ! protein-containing material entity relationship: BFO:0000051 CHEBI:33697 ! has part ribonucleic acid relationship: RO:0002216 GO:0006412 ! capable of part of translation [Term] id: GO:0005856 name: cytoskeleton namespace: cellular_component def: "A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles." [GOC:mah, PMID:16959967, PMID:27419875] xref: Wikipedia:Cytoskeleton is_a: GO:0043232 ! intracellular non-membrane-bounded organelle [Term] id: GO:0005874 name: microtubule namespace: cellular_component def: "Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle." [ISBN:0879693568] synonym: "microtubuli" EXACT [] synonym: "microtubulus" EXACT [] xref: NIF_Subcellular:sao1846835077 xref: Wikipedia:Microtubule is_a: GO:0099513 ! polymeric cytoskeletal fiber relationship: BFO:0000050 GO:0015630 ! part of microtubule cytoskeleton [Term] id: GO:0005879 name: axonemal microtubule namespace: cellular_component def: "A microtubule in the axoneme of a eukaryotic cilium or flagellum; an axoneme contains nine modified doublet microtubules, which may or may not surround a pair of single microtubules." [GOC:cilia, ISBN:0815316194] is_a: GO:0005881 ! cytoplasmic microtubule intersection_of: GO:0005874 ! microtubule intersection_of: BFO:0000050 GO:0005930 ! part of axoneme relationship: BFO:0000050 GO:0005930 ! part of axoneme [Term] id: GO:0005880 name: nuclear microtubule namespace: cellular_component def: "Any microtubule in the nucleus of a cell." [GOC:mah] is_a: GO:0005874 ! microtubule intersection_of: GO:0005874 ! microtubule intersection_of: BFO:0000050 GO:0005634 ! part of nucleus relationship: BFO:0000050 GO:0005634 ! part of nucleus [Term] id: GO:0005881 name: cytoplasmic microtubule namespace: cellular_component def: "Any microtubule in the cytoplasm of a cell." [GOC:mah] is_a: GO:0005874 ! microtubule intersection_of: GO:0005874 ! microtubule intersection_of: BFO:0000050 GO:0005737 ! part of cytoplasm relationship: BFO:0000050 GO:0005737 ! part of cytoplasm [Term] id: GO:0005884 name: actin filament namespace: cellular_component def: "A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane." [GOC:mah, ISBN:0198506732, PMID:10666339] synonym: "microfilament" EXACT [] xref: FMA:63850 xref: NIF_Subcellular:sao1588493326 xref: Wikipedia:Actin is_a: GO:0099513 ! polymeric cytoskeletal fiber relationship: BFO:0000050 GO:0015629 ! part of actin cytoskeleton [Term] id: GO:0005886 name: plasma membrane namespace: cellular_component def: "The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins." [ISBN:0716731363] synonym: "cell membrane" EXACT [] synonym: "cellular membrane" EXACT [NIF_Subcellular:sao6433132645] synonym: "cytoplasmic membrane" EXACT [] synonym: "plasmalemma" EXACT [] xref: NIF_Subcellular:sao1663586795 xref: Wikipedia:Cell_membrane is_a: GO:0016020 ! membrane relationship: BFO:0000050 GO:0071944 ! part of cell periphery [Term] id: GO:0005902 name: microvillus namespace: cellular_component def: "Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. Present in especially large numbers on the absorptive surface of intestinal cells." [ISBN:0815316194] xref: NIF_Subcellular:sao671419673 xref: Wikipedia:Microvillus is_a: GO:0098858 ! actin-based cell projection relationship: BFO:0000050 CL:0000066 ! part of epithelial cell relationship: BFO:0000051 GO:0032432 ! has part actin filament bundle [Term] id: GO:0005911 name: cell-cell junction namespace: cellular_component def: "A cell junction that forms a connection between two or more cells of an organism; excludes direct cytoplasmic intercellular bridges, such as ring canals in insects." [GOC:aruk, GOC:bc, GOC:dgh, GOC:hb, GOC:mah, PMID:21422226, PMID:28096264] synonym: "intercellular junction" EXACT [NIF_Subcellular:sao1395777368] xref: NIF_Subcellular:sao1922892319 is_a: GO:0070161 ! anchoring junction [Term] id: GO:0005929 name: cilium namespace: cellular_component def: "A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body." [GOC:cilia, GOC:curators, GOC:kmv, GOC:vw, ISBN:0198547684, PMID:16824949, PMID:17009929, PMID:20144998] synonym: "eukaryotic flagellum" EXACT [] synonym: "microtubule-based flagellum" EXACT [] xref: FMA:67181 xref: NIF_Subcellular:sao787716553 xref: Wikipedia:Cilium is_a: GO:0043227 ! membrane-bounded organelle is_a: GO:0120025 ! plasma membrane bounded cell projection is_a: PR:000050567 ! protein-containing material entity relationship: BFO:0000051 GO:0030990 ! has part intraciliary transport particle relationship: RO:0002160 NCBITaxon:2759 ! only in taxon Eukaryota relationship: RO:0002162 NCBITaxon:2759 {all_only="true"} ! in taxon Eukaryota [Term] id: GO:0005930 name: axoneme namespace: cellular_component def: "The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements." [GOC:bf, GOC:cilia, ISBN:0198547684] synonym: "ciliary axoneme" EXACT [] synonym: "cilium axoneme" EXACT [] synonym: "flagellar axoneme" EXACT [] synonym: "flagellum axoneme" EXACT [] xref: Wikipedia:Axoneme is_a: GO:0110165 ! cellular anatomical entity relationship: BFO:0000050 GO:0005856 ! part of cytoskeleton relationship: BFO:0000050 GO:0097014 ! part of ciliary plasm relationship: BFO:0000051 GO:0005874 ! has part microtubule [Term] id: GO:0005938 name: cell cortex namespace: cellular_component def: "The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins." [GOC:mah, ISBN:0815316194] xref: Wikipedia:Cell_cortex is_a: GO:0005737 ! cytoplasm intersection_of: GO:0005737 ! cytoplasm intersection_of: BFO:0000050 GO:0071944 ! part of cell periphery relationship: BFO:0000050 GO:0071944 ! part of cell periphery [Term] id: GO:0005975 name: carbohydrate metabolic process namespace: biological_process def: "The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y." [GOC:mah, ISBN:0198506732] synonym: "carbohydrate metabolism" EXACT [] xref: Wikipedia:Carbohydrate_metabolism is_a: GO:0044238 ! primary metabolic process is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:16646 ! has primary input or output carbohydrate relationship: RO:0004007 CHEBI:16646 ! has primary input or output carbohydrate creation_date: 2012-10-23T15:40:34Z [Term] id: GO:0005976 name: polysaccharide metabolic process namespace: biological_process def: "The chemical reactions and pathways involving a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." [ISBN:0198547684] synonym: "polysaccharide metabolism" EXACT [] is_a: GO:0005975 ! carbohydrate metabolic process is_a: GO:0043170 ! macromolecule metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:18154 ! has primary input or output polysaccharide relationship: RO:0004007 CHEBI:18154 ! has primary input or output polysaccharide [Term] id: GO:0005977 name: glycogen metabolic process namespace: biological_process def: "The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages." [ISBN:0198506732] synonym: "glycogen metabolism" EXACT [] is_a: GO:0006112 ! energy reserve metabolic process is_a: GO:0044042 ! glucan metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:28087 ! has primary input or output glycogen relationship: RO:0004007 CHEBI:28087 ! has primary input or output glycogen [Term] id: GO:0005978 name: glycogen biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues." [ISBN:0198506732] synonym: "glycogen anabolism" EXACT [] synonym: "glycogen biosynthesis" EXACT [] synonym: "glycogen formation" EXACT [] synonym: "glycogen synthesis" EXACT [] xref: MetaCyc:GLYCOGENSYNTH-PWY is_a: GO:0005977 ! glycogen metabolic process is_a: GO:0009250 ! glucan biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:28087 ! has primary output glycogen relationship: RO:0004008 CHEBI:28087 ! has primary output glycogen [Term] id: GO:0005979 name: regulation of glycogen biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen." [GOC:go_curators] synonym: "regulation of glycogen anabolism" EXACT [] synonym: "regulation of glycogen biosynthesis" EXACT [] synonym: "regulation of glycogen formation" EXACT [] synonym: "regulation of glycogen synthesis" EXACT [] is_a: GO:0010962 ! regulation of glucan biosynthetic process is_a: GO:0070873 ! regulation of glycogen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0005978 ! regulates (processual) glycogen biosynthetic process relationship: RO:0002211 GO:0005978 ! regulates (processual) glycogen biosynthetic process [Term] id: GO:0005980 name: glycogen catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues." [ISBN:0198506732] synonym: "glycogen breakdown" EXACT [] synonym: "glycogen catabolism" EXACT [] synonym: "glycogen degradation" EXACT [] synonym: "glycogenolysis" EXACT [GOC:sl] xref: MetaCyc:GLYCOCAT-PWY is_a: GO:0005977 ! glycogen metabolic process is_a: GO:0009251 ! glucan catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:28087 ! has primary input glycogen relationship: RO:0004009 CHEBI:28087 ! has primary input glycogen [Term] id: GO:0005981 name: regulation of glycogen catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen." [GOC:go_curators] synonym: "regulation of glycogen breakdown" EXACT [] synonym: "regulation of glycogen catabolism" EXACT [] synonym: "regulation of glycogen degradation" EXACT [] synonym: "regulation of glycogenolysis" EXACT [GOC:sl] is_a: GO:0043470 ! regulation of carbohydrate catabolic process is_a: GO:0070873 ! regulation of glycogen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0005980 ! regulates (processual) glycogen catabolic process relationship: RO:0002211 GO:0005980 ! regulates (processual) glycogen catabolic process [Term] id: GO:0005996 name: monosaccharide metabolic process namespace: biological_process def: "The chemical reactions and pathways involving monosaccharides, the simplest carbohydrates. They are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides." [ISBN:0198506732] synonym: "monosaccharide metabolism" EXACT [] is_a: GO:0005975 ! carbohydrate metabolic process is_a: GO:0044281 ! small molecule metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:35381 ! has primary input or output monosaccharide relationship: RO:0004007 CHEBI:35381 ! has primary input or output monosaccharide [Term] id: GO:0006006 name: glucose metabolic process namespace: biological_process def: "The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides." [ISBN:0198506732] synonym: "cellular glucose metabolic process" EXACT [GOC:vw] synonym: "glucose metabolism" EXACT [] is_a: GO:0019318 ! hexose metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:17234 ! has primary input or output glucose relationship: RO:0004007 CHEBI:17234 ! has primary input or output glucose [Term] id: GO:0006007 name: glucose catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of glucose, the aldohexose gluco-hexose." [GOC:ai] synonym: "glucose breakdown" EXACT [] synonym: "glucose catabolism" EXACT [] synonym: "glucose degradation" EXACT [] is_a: GO:0006006 ! glucose metabolic process is_a: GO:0019320 ! hexose catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:17234 ! has primary input glucose relationship: RO:0004009 CHEBI:17234 ! has primary input glucose [Term] id: GO:0006022 name: aminoglycan metabolic process namespace: biological_process def: "The chemical reactions and pathways involving aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages." [GOC:ai, ISBN:0198506732] synonym: "aminoglycan metabolism" EXACT [] is_a: GO:0043170 ! macromolecule metabolic process is_a: GO:1901135 ! carbohydrate derivative metabolic process is_a: GO:1901564 ! organonitrogen compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:22506 ! has primary input or output aminoglycan relationship: RO:0004007 CHEBI:22506 ! has primary input or output aminoglycan [Term] id: GO:0006023 name: aminoglycan biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages." [GOC:ai, ISBN:0198506732] synonym: "aminoglycan anabolism" EXACT [] synonym: "aminoglycan biosynthesis" EXACT [] synonym: "aminoglycan formation" EXACT [] synonym: "aminoglycan synthesis" EXACT [] is_a: GO:0006022 ! aminoglycan metabolic process is_a: GO:0009059 ! macromolecule biosynthetic process is_a: GO:1901137 ! carbohydrate derivative biosynthetic process is_a: GO:1901566 ! organonitrogen compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:22506 ! has primary output aminoglycan relationship: RO:0004008 CHEBI:22506 ! has primary output aminoglycan [Term] id: GO:0006024 name: glycosaminoglycan biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of glycosaminoglycans, any of a group of polysaccharides that contain amino sugars." [ISBN:0192800981] synonym: "glycosaminoglycan anabolism" EXACT [] synonym: "glycosaminoglycan biosynthesis" EXACT [] synonym: "glycosaminoglycan formation" EXACT [] synonym: "glycosaminoglycan synthesis" EXACT [] is_a: GO:0006023 ! aminoglycan biosynthetic process is_a: GO:0030203 ! glycosaminoglycan metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:18085 ! has primary output glycosaminoglycan relationship: RO:0004008 CHEBI:18085 ! has primary output glycosaminoglycan [Term] id: GO:0006026 name: aminoglycan catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages." [GOC:ai, ISBN:0198506732] synonym: "aminoglycan breakdown" EXACT [] synonym: "aminoglycan catabolism" EXACT [] synonym: "aminoglycan degradation" EXACT [] is_a: GO:0006022 ! aminoglycan metabolic process is_a: GO:0009057 ! macromolecule catabolic process is_a: GO:1901136 ! carbohydrate derivative catabolic process is_a: GO:1901565 ! organonitrogen compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:22506 ! has primary input aminoglycan relationship: RO:0004009 CHEBI:22506 ! has primary input aminoglycan [Term] id: GO:0006027 name: glycosaminoglycan catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of glycosaminoglycans, any one of a group of polysaccharides that contain amino sugars." [ISBN:0192800981] synonym: "glycosaminoglycan breakdown" EXACT [] synonym: "glycosaminoglycan catabolism" EXACT [] synonym: "glycosaminoglycan degradation" EXACT [] is_a: GO:0006026 ! aminoglycan catabolic process is_a: GO:0030203 ! glycosaminoglycan metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:18085 ! has primary input glycosaminoglycan relationship: RO:0004009 CHEBI:18085 ! has primary input glycosaminoglycan [Term] id: GO:0006030 name: chitin metabolic process namespace: biological_process def: "The chemical reactions and pathways involving chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues." [GOC:jl, ISBN:0198506732] synonym: "beta-1,4-linked N-acetylglucosamine metabolic process" EXACT [] synonym: "beta-1,4-linked N-acetylglucosamine metabolism" EXACT [] synonym: "chitin metabolism" EXACT [] is_a: GO:0006022 ! aminoglycan metabolic process is_a: GO:1901071 ! glucosamine-containing compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:17029 ! has primary input or output chitin relationship: RO:0004007 CHEBI:17029 ! has primary input or output chitin [Term] id: GO:0006031 name: chitin biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues." [GOC:jl, ISBN:0198506732] synonym: "beta-1,4-linked N-acetylglucosamine biosynthesis" EXACT [] synonym: "beta-1,4-linked N-acetylglucosamine biosynthetic process" EXACT [] synonym: "chitin anabolism" EXACT [] synonym: "chitin biosynthesis" EXACT [] synonym: "chitin formation" EXACT [] synonym: "chitin synthesis" EXACT [] is_a: GO:0006023 ! aminoglycan biosynthetic process is_a: GO:0006030 ! chitin metabolic process is_a: GO:1901073 ! glucosamine-containing compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:17029 ! has primary output chitin relationship: RO:0004008 CHEBI:17029 ! has primary output chitin [Term] id: GO:0006032 name: chitin catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues." [GOC:jl, ISBN:0198506732] synonym: "beta-1,4-linked N-acetylglucosamine catabolic process" EXACT [] synonym: "beta-1,4-linked N-acetylglucosamine catabolism" EXACT [] synonym: "chitin breakdown" EXACT [] synonym: "chitin catabolism" EXACT [] synonym: "chitin degradation" EXACT [] is_a: GO:0006026 ! aminoglycan catabolic process is_a: GO:0006030 ! chitin metabolic process is_a: GO:1901072 ! glucosamine-containing compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:17029 ! has primary input chitin relationship: RO:0004009 CHEBI:17029 ! has primary input chitin [Term] id: GO:0006040 name: amino sugar metabolic process namespace: biological_process def: "The chemical reactions and pathways involving any amino sugar, sugars containing an amino group in place of a hydroxyl group." [GOC:jl, ISBN:0192801023] synonym: "amino sugar metabolism" EXACT [] synonym: "aminosaccharide metabolic process" EXACT [] synonym: "aminosaccharide metabolism" EXACT [] is_a: GO:1901135 ! carbohydrate derivative metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:28963 ! has primary input or output amino sugar relationship: RO:0004007 CHEBI:28963 ! has primary input or output amino sugar [Term] id: GO:0006082 name: organic acid metabolic process namespace: biological_process def: "The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage." [ISBN:0198506732] synonym: "organic acid metabolism" EXACT [] is_a: GO:0044237 ! cellular metabolic process is_a: GO:0044281 ! small molecule metabolic process is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:64709 ! has primary input or output organic acid relationship: RO:0004007 CHEBI:64709 ! has primary input or output organic acid [Term] id: GO:0006083 name: acetate metabolic process namespace: biological_process def: "The chemical reactions and pathways involving acetate, the anion of acetic acid." [GOC:go_curators] synonym: "acetate metabolism" EXACT [] is_a: GO:0032787 ! monocarboxylic acid metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:30089 ! has primary input or output acetate relationship: RO:0004007 CHEBI:30089 ! has primary input or output acetate [Term] id: GO:0006091 name: generation of precursor metabolites and energy namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances." [GOC:jl] is_a: GO:0044237 ! cellular metabolic process [Term] id: GO:0006094 name: gluconeogenesis namespace: biological_process def: "The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol." [MetaCyc:GLUCONEO-PWY] synonym: "glucose biosynthesis" EXACT [] synonym: "glucose biosynthetic process" EXACT [] xref: MetaCyc:GLUCONEO-PWY xref: Wikipedia:Gluconeogenesis is_a: GO:0006006 ! glucose metabolic process is_a: GO:0019319 ! hexose biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:17234 ! has primary output glucose relationship: RO:0004008 CHEBI:17234 ! has primary output glucose [Term] id: GO:0006109 name: regulation of carbohydrate metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates." [GOC:go_curators] synonym: "regulation of carbohydrate metabolism" EXACT [] is_a: GO:0080090 ! regulation of primary metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0005975 ! regulates (processual) carbohydrate metabolic process relationship: RO:0002211 GO:0005975 ! regulates (processual) carbohydrate metabolic process [Term] id: GO:0006111 name: regulation of gluconeogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of gluconeogenesis, the formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol." [GOC:go_curators] is_a: GO:0010906 ! regulation of glucose metabolic process is_a: GO:0043255 ! regulation of carbohydrate biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006094 ! regulates (processual) gluconeogenesis relationship: RO:0002211 GO:0006094 ! regulates (processual) gluconeogenesis creation_date: 2013-01-18T12:47:43Z [Term] id: GO:0006112 name: energy reserve metabolic process namespace: biological_process def: "The chemical reactions and pathways by which a cell derives energy from stored compounds such as fats or glycogen." [GOC:mah] synonym: "energy reserve metabolism" EXACT [] is_a: GO:0015980 ! energy derivation by oxidation of organic compounds [Term] id: GO:0006139 name: nucleobase-containing compound metabolic process namespace: biological_process def: "Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:ai] synonym: "cellular nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT [] synonym: "cellular nucleobase, nucleoside, nucleotide and nucleic acid metabolism" EXACT [] synonym: "nucleobase, nucleoside, nucleotide and nucleic acid metabolism" EXACT [] is_a: GO:0006725 ! cellular aromatic compound metabolic process is_a: GO:0034641 ! cellular nitrogen compound metabolic process is_a: GO:0044238 ! primary metabolic process is_a: GO:0046483 ! heterocycle metabolic process is_a: GO:1901360 ! organic cyclic compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:61120 ! has primary input or output nucleobase-containing molecular entity relationship: RO:0004007 CHEBI:61120 ! has primary input or output nucleobase-containing molecular entity [Term] id: GO:0006259 name: DNA metabolic process namespace: biological_process def: "Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides." [ISBN:0198506732] synonym: "cellular DNA metabolism" EXACT [] synonym: "DNA metabolism" EXACT [] is_a: GO:0090304 ! nucleic acid metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:16991 ! has primary input or output deoxyribonucleic acid relationship: RO:0004007 CHEBI:16991 ! has primary input or output deoxyribonucleic acid [Term] id: GO:0006308 name: DNA catabolic process namespace: biological_process def: "The cellular DNA metabolic process resulting in the breakdown of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one." [GOC:go_curators, ISBN:0198506732] synonym: "DNA breakdown" EXACT [] synonym: "DNA catabolism" EXACT [] synonym: "DNA degradation" EXACT [] is_a: GO:0006259 ! DNA metabolic process is_a: GO:0009057 ! macromolecule catabolic process is_a: GO:0034655 ! nucleobase-containing compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:16991 ! has primary input deoxyribonucleic acid relationship: BFO:0000051 GO:0004536 ! has part DNA nuclease activity relationship: RO:0004009 CHEBI:16991 ! has primary input deoxyribonucleic acid [Term] id: GO:0006309 name: apoptotic DNA fragmentation namespace: biological_process def: "The cleavage of DNA during apoptosis, which usually occurs in two stages: cleavage into fragments of about 50 kbp followed by cleavage between nucleosomes to yield 200 bp fragments." [GOC:dph, GOC:mah, GOC:mtg_apoptosis, GOC:tb, ISBN:0721639976, PMID:15723341, PMID:23379520] synonym: "DNA catabolic process during apoptosis" EXACT [] synonym: "DNA catabolism during apoptosis" EXACT [] synonym: "DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:cjm, GOC:dph, GOC:tb] synonym: "endonucleolytic DNA catabolic process involved in apoptosis" EXACT [] is_a: GO:0006308 ! DNA catabolic process intersection_of: GO:0006308 ! DNA catabolic process intersection_of: BFO:0000050 GO:0030262 ! part of apoptotic nuclear changes relationship: BFO:0000050 GO:0030262 ! part of apoptotic nuclear changes [Term] id: GO:0006325 name: chromatin organization namespace: biological_process def: "The assembly or remodeling of chromatin composed of DNA complexed with histones, other associated proteins, and sometimes RNA." [PMID:20404130] synonym: "chromatin organisation" EXACT [GOC:mah] synonym: "establishment of chromatin architecture" EXACT [GOC:mah] synonym: "establishment or maintenance of chromatin architecture" EXACT [GOC:mah] is_a: GO:0071824 ! protein-DNA complex organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0000785 ! results in organization of chromatin relationship: RO:0002592 GO:0000785 ! results in organization of chromatin [Term] id: GO:0006401 name: RNA catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage." [ISBN:0198506732] synonym: "RNA breakdown" EXACT [] synonym: "RNA catabolism" EXACT [] synonym: "RNA degradation" EXACT [] is_a: GO:0009057 ! macromolecule catabolic process is_a: GO:0016070 ! RNA metabolic process is_a: GO:0034655 ! nucleobase-containing compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:33697 ! has primary input ribonucleic acid relationship: RO:0004009 CHEBI:33697 ! has primary input ribonucleic acid [Term] id: GO:0006403 name: RNA localization namespace: biological_process def: "A process in which RNA is transported to, or maintained in, a specific location." [GOC:ai] synonym: "establishment and maintenance of RNA localization" EXACT [] synonym: "RNA localisation" EXACT [GOC:mah] is_a: GO:0033036 ! macromolecule localization [Term] id: GO:0006412 name: translation namespace: biological_process namespace: protein def: "The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome." [GOC:go_curators] synonym: "protein anabolism" EXACT [] synonym: "protein biosynthesis" EXACT [] synonym: "protein biosynthetic process" EXACT [] synonym: "protein formation" EXACT [] synonym: "protein synthesis" EXACT [] synonym: "protein translation" EXACT [] xref: Wikipedia:Translation_(genetics) is_a: GO:0009059 ! macromolecule biosynthetic process is_a: GO:0019538 ! protein metabolic process is_a: GO:0043043 ! peptide biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: BFO:0000050 GO:0010467 ! part of gene expression intersection_of: RO:0004008 CHEBI:16541 ! has primary output protein polypeptide chain relationship: BFO:0000050 GO:0010467 ! part of gene expression relationship: BFO:0000051 GO:0006414 ! has part translational elongation relationship: RO:0002224 GO:0006413 ! starts with translational initiation relationship: RO:0002230 GO:0006415 ! ends with translational termination relationship: RO:0004008 CHEBI:16541 ! has primary output protein polypeptide chain [Term] id: GO:0006413 name: translational initiation namespace: biological_process def: "The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA." [ISBN:019879276X] synonym: "translation initiation" EXACT [] is_a: GO:0044237 ! cellular metabolic process relationship: BFO:0000050 GO:0006412 ! part of translation relationship: RO:0002224 GO:0001677 ! starts with formation of translation initiation ternary complex [Term] id: GO:0006414 name: translational elongation namespace: biological_process def: "The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis." [GOC:ems] synonym: "translation elongation" EXACT [] is_a: GO:0009059 ! macromolecule biosynthetic process relationship: BFO:0000050 GO:0006412 ! part of translation [Term] id: GO:0006415 name: translational termination namespace: biological_process def: "The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code)." [GOC:hjd, ISBN:019879276X] synonym: "translation termination" EXACT [] synonym: "translational complex disassembly" EXACT [] is_a: GO:0032984 ! protein-containing complex disassembly relationship: BFO:0000050 GO:0006412 ! part of translation [Term] id: GO:0006417 name: regulation of translation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA." [GOC:isa_complete] synonym: "regulation of protein anabolism" EXACT [] synonym: "regulation of protein biosynthesis" EXACT [] synonym: "regulation of protein formation" EXACT [] synonym: "regulation of protein synthesis" EXACT [] is_a: GO:0010608 ! post-transcriptional regulation of gene expression is_a: GO:0034248 ! regulation of amide metabolic process is_a: GO:0051246 ! regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006412 ! regulates (processual) translation relationship: RO:0002211 GO:0006412 ! regulates (processual) translation [Term] id: GO:0006446 name: regulation of translational initiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of translational initiation." [GOC:go_curators] is_a: GO:0006417 ! regulation of translation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006413 ! regulates (processual) translational initiation relationship: RO:0002211 GO:0006413 ! regulates (processual) translational initiation [Term] id: GO:0006448 name: regulation of translational elongation namespace: biological_process def: "Any process that modulates the frequency, rate, extent or accuracy of translational elongation." [GOC:go_curators] is_a: GO:0006417 ! regulation of translation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006414 ! regulates (processual) translational elongation relationship: RO:0002211 GO:0006414 ! regulates (processual) translational elongation [Term] id: GO:0006449 name: regulation of translational termination namespace: biological_process def: "Any process that modulates the frequency, rate or extent of translational termination." [GOC:go_curators] is_a: GO:0006417 ! regulation of translation is_a: GO:0043244 ! regulation of protein-containing complex disassembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006415 ! regulates (processual) translational termination relationship: RO:0002211 GO:0006415 ! regulates (processual) translational termination [Term] id: GO:0006516 name: glycoprotein catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:go_curators, ISBN:0198506732] synonym: "glycoprotein breakdown" EXACT [] synonym: "glycoprotein catabolism" EXACT [] synonym: "glycoprotein degradation" EXACT [] is_a: GO:0009057 ! macromolecule catabolic process is_a: GO:0009100 ! glycoprotein metabolic process is_a: GO:1901136 ! carbohydrate derivative catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:17089 ! has primary input glycoprotein relationship: RO:0004009 CHEBI:17089 ! has primary input glycoprotein [Term] id: GO:0006518 name: peptide metabolic process namespace: biological_process def: "The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another." [GOC:go_curators] synonym: "peptide metabolism" EXACT [] is_a: GO:0043603 ! amide metabolic process is_a: GO:1901564 ! organonitrogen compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:16670 ! has primary input or output peptide relationship: RO:0004007 CHEBI:16670 ! has primary input or output peptide [Term] id: GO:0006520 name: amino acid metabolic process namespace: biological_process def: "The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups." [ISBN:0198506732] synonym: "cellular amino acid metabolic process" EXACT [] synonym: "cellular amino acid metabolism" EXACT [] is_a: GO:0044238 ! primary metabolic process is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:35238 ! has primary input or output amino acid zwitterion relationship: RO:0004007 CHEBI:35238 ! has primary input or output amino acid zwitterion [Term] id: GO:0006521 name: regulation of cellular amino acid metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids." [GOC:go_curators] synonym: "regulation of amino acid metabolism" EXACT [] is_a: GO:0010565 ! regulation of cellular ketone metabolic process is_a: GO:0033238 ! regulation of amine metabolic process is_a: GO:0080090 ! regulation of primary metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006520 ! regulates (processual) amino acid metabolic process relationship: RO:0002211 GO:0006520 ! regulates (processual) amino acid metabolic process [Term] id: GO:0006576 name: biogenic amine metabolic process namespace: biological_process def: "The chemical reactions and pathways occurring at the level of individual cells involving any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters." [GOC:jl, ISBN:0395825172] synonym: "biogenic amine metabolism" EXACT [] synonym: "cellular biogenic amine metabolic process" EXACT [] is_a: GO:0009308 ! amine metabolic process [Term] id: GO:0006581 name: acetylcholine catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of acetylcholine, the acetic acid ester of the organic base choline." [GOC:jl, ISBN:0192800752] synonym: "acetylcholine breakdown" EXACT [] synonym: "acetylcholine catabolism" EXACT [] synonym: "acetylcholine degradation" EXACT [] is_a: GO:0008291 ! acetylcholine metabolic process is_a: GO:1901575 ! organic substance catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:15355 ! has primary input acetylcholine relationship: RO:0004009 CHEBI:15355 ! has primary input acetylcholine [Term] id: GO:0006584 name: catecholamine metabolic process namespace: biological_process def: "The chemical reactions and pathways involving any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." [GOC:jl, ISBN:0198506732] synonym: "catecholamine metabolism" EXACT [] is_a: GO:0006576 ! biogenic amine metabolic process is_a: GO:0009712 ! catechol-containing compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:33567 ! has primary input or output catecholamine relationship: RO:0004007 CHEBI:33567 ! has primary input or output catecholamine [Term] id: GO:0006586 name: indolalkylamine metabolic process namespace: biological_process def: "The chemical reactions and pathways involving indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group." [GOC:curators] synonym: "indolalkylamine metabolism" EXACT [] is_a: GO:0006576 ! biogenic amine metabolic process is_a: GO:0042430 ! indole-containing compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:38631 ! has primary input or output aminoalkylindole relationship: RO:0004007 CHEBI:38631 ! has primary input or output aminoalkylindole [Term] id: GO:0006629 name: lipid metabolic process namespace: biological_process def: "The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids." [GOC:ma] synonym: "lipid metabolism" EXACT [] xref: Wikipedia:Lipid_metabolism is_a: GO:0044238 ! primary metabolic process is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:18059 ! has primary input or output lipid relationship: RO:0004007 CHEBI:18059 ! has primary input or output lipid [Term] id: GO:0006694 name: steroid biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification." [GOC:go_curators] synonym: "steroid anabolism" EXACT [] synonym: "steroid biosynthesis" EXACT [] synonym: "steroid formation" EXACT [] synonym: "steroid synthesis" EXACT [] synonym: "steroidogenesis" EXACT [] xref: Wikipedia:Steroid_metabolisms#Steroid_biosynthesis is_a: GO:0008202 ! steroid metabolic process is_a: GO:0008610 ! lipid biosynthetic process is_a: GO:1901362 ! organic cyclic compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:35341 ! has primary output steroid relationship: RO:0004008 CHEBI:35341 ! has primary output steroid [Term] id: GO:0006699 name: bile acid biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of bile acids, any of a group of steroid carboxylic acids occurring in bile." [GOC:go_curators] synonym: "bile acid anabolism" EXACT [] synonym: "bile acid biosynthesis" EXACT [] synonym: "bile acid formation" EXACT [] synonym: "bile acid synthesis" EXACT [] is_a: GO:0006694 ! steroid biosynthetic process is_a: GO:0008206 ! bile acid metabolic process is_a: GO:0072330 ! monocarboxylic acid biosynthetic process is_a: GO:1901617 ! organic hydroxy compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:36235 ! has primary output bile acid anion relationship: RO:0004008 CHEBI:36235 ! has primary output bile acid anion [Term] id: GO:0006706 name: steroid catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus." [GOC:go_curators] synonym: "steroid breakdown" EXACT [] synonym: "steroid catabolism" EXACT [] synonym: "steroid degradation" EXACT [] is_a: GO:0008202 ! steroid metabolic process is_a: GO:0016042 ! lipid catabolic process is_a: GO:1901361 ! organic cyclic compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:35341 ! has primary input steroid relationship: RO:0004009 CHEBI:35341 ! has primary input steroid [Term] id: GO:0006725 name: cellular aromatic compound metabolic process namespace: biological_process def: "The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells." [GOC:ai, ISBN:0198506732] synonym: "aromatic compound metabolism" EXACT [] is_a: GO:0044237 ! cellular metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:33655 ! has primary input or output aromatic compound relationship: RO:0004007 CHEBI:33655 ! has primary input or output aromatic compound [Term] id: GO:0006790 name: sulfur compound metabolic process namespace: biological_process def: "The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione." [GOC:ai] synonym: "sulfur metabolism" EXACT [] synonym: "sulphur metabolic process" EXACT [] synonym: "sulphur metabolism" EXACT [] xref: Wikipedia:Sulfur_metabolism is_a: GO:0044237 ! cellular metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:26835 ! has primary input or output sulfur molecular entity relationship: RO:0004007 CHEBI:26835 ! has primary input or output sulfur molecular entity [Term] id: GO:0006793 name: phosphorus metabolic process namespace: biological_process def: "The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4)." [GOC:ai] synonym: "phosphorus metabolism" EXACT [] is_a: GO:0044237 ! cellular metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:26082 ! has primary input or output phosphorus molecular entity relationship: RO:0004007 CHEBI:26082 ! has primary input or output phosphorus molecular entity [Term] id: GO:0006796 name: phosphate-containing compound metabolic process namespace: biological_process def: "The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid." [GOC:ai] synonym: "phosphate metabolism" EXACT [] is_a: GO:0006793 ! phosphorus metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:26020 ! has primary input or output phosphate relationship: RO:0004007 CHEBI:26020 ! has primary input or output phosphate [Term] id: GO:0006807 name: nitrogen compound metabolic process namespace: biological_process def: "The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen." [GOC:jl, ISBN:0198506732] synonym: "nitrogen compound metabolism" EXACT [] is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:51143 ! has primary input or output nitrogen molecular entity relationship: RO:0004007 CHEBI:51143 ! has primary input or output nitrogen molecular entity [Term] id: GO:0006810 name: transport namespace: biological_process def: "The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or a transporter complex, a pore or a motor protein." [GOC:dos, GOC:dph, GOC:jl, GOC:mah] is_a: GO:0051234 ! establishment of localization creation_date: 2012-12-13T16:25:32Z [Term] id: GO:0006811 name: monoatomic ion transport namespace: biological_process def: "The directed movement of a monoatomic ion into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monatomic ions (also called simple ions) are ions consisting of exactly one atom." [GOC:ai] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:24867 ! has primary input monoatomic ion relationship: RO:0004009 CHEBI:24867 ! has primary input monoatomic ion [Term] id: GO:0006812 name: monoatomic cation transport namespace: biological_process def: "The directed movement of a monoatomic cation, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monatomic cations (also called simple cations) are positively charged ions consisting of exactly one atom." [GOC:ai] is_a: GO:0006811 ! monoatomic ion transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:23906 ! has primary input monoatomic cation relationship: RO:0004009 CHEBI:23906 ! has primary input monoatomic cation [Term] id: GO:0006814 name: sodium ion transport namespace: biological_process def: "The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "sodium transport" EXACT [] is_a: GO:0030001 ! metal ion transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:29101 ! has primary input sodium(1+) relationship: RO:0004009 CHEBI:29101 ! has primary input sodium(1+) [Term] id: GO:0006817 name: phosphate ion transport namespace: biological_process def: "The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] is_a: GO:0015698 ! inorganic anion transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:35780 ! has primary input phosphate ion relationship: RO:0004009 CHEBI:35780 ! has primary input phosphate ion [Term] id: GO:0006835 name: dicarboxylic acid transport namespace: biological_process def: "The directed movement of dicarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] is_a: GO:0046942 ! carboxylic acid transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:35693 ! has primary input dicarboxylic acid anion relationship: RO:0004009 CHEBI:35693 ! has primary input dicarboxylic acid anion [Term] id: GO:0006836 name: neurotransmitter transport namespace: biological_process def: "The directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell." [GOC:ai] is_a: GO:0006810 ! transport relationship: RO:0002160 NCBITaxon:33208 ! only in taxon Metazoa relationship: RO:0002162 NCBITaxon:33208 {all_only="true"} ! in taxon Metazoa [Term] id: GO:0006837 name: serotonin transport namespace: biological_process def: "The directed movement of serotonin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems." [GOC:ai] is_a: GO:0071705 ! nitrogen compound transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:350546 ! has primary input serotonin(1+) relationship: RO:0004009 CHEBI:350546 ! has primary input serotonin(1+) [Term] id: GO:0006846 name: acetate transport namespace: biological_process def: "The directed movement of acetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] is_a: GO:0015718 ! monocarboxylic acid transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:30089 ! has primary input acetate relationship: RO:0004009 CHEBI:30089 ! has primary input acetate [Term] id: GO:0006847 name: plasma membrane acetate transport namespace: biological_process def: "The directed movement of acetate across a plasma membrane." [GOC:ai] is_a: GO:0035433 ! acetate transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002342 GO:0005886 ! results in transport across plasma membrane intersection_of: RO:0004009 CHEBI:30089 ! has primary input acetate relationship: RO:0002342 GO:0005886 ! results in transport across plasma membrane [Term] id: GO:0006858 name: extracellular transport namespace: biological_process def: "The transport of substances that occurs outside cells." [GOC:go_curators] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: BFO:0000066 GO:0005576 ! occurs in extracellular region relationship: BFO:0000066 GO:0005576 ! occurs in extracellular region [Term] id: GO:0006860 name: extracellular amino acid transport namespace: biological_process def: "The directed extracellular movement of amino acids." [GOC:ai] is_a: GO:0006858 ! extracellular transport is_a: GO:0006865 ! amino acid transport intersection_of: GO:0006865 ! amino acid transport intersection_of: BFO:0000066 GO:0005576 ! occurs in extracellular region [Term] id: GO:0006865 name: amino acid transport namespace: biological_process def: "The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] is_a: GO:0015849 ! organic acid transport is_a: GO:0071705 ! nitrogen compound transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:33709 ! has primary input amino acid relationship: RO:0004009 CHEBI:33709 ! has primary input amino acid [Term] id: GO:0006869 name: lipid transport namespace: biological_process def: "The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent." [ISBN:0198506732] is_a: GO:0071702 ! organic substance transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:18059 ! has primary input lipid relationship: BFO:0000050 GO:0010876 ! part of lipid localization relationship: RO:0004009 CHEBI:18059 ! has primary input lipid [Term] id: GO:0006886 name: intracellular protein transport namespace: biological_process def: "The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell." [GOC:mah] is_a: GO:0015031 ! protein transport is_a: GO:0046907 ! intracellular transport intersection_of: GO:0006810 ! transport intersection_of: BFO:0000066 GO:0005622 ! occurs in intracellular anatomical structure intersection_of: RO:0004009 PR:000000001 ! has primary input protein relationship: BFO:0000050 GO:0008104 ! part of protein localization [Term] id: GO:0006887 name: exocytosis namespace: biological_process def: "A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell." [GOC:mah, ISBN:0716731363, PMID:22323285] synonym: "vesicle exocytosis" EXACT [] xref: Wikipedia:Exocytosis is_a: GO:0016192 ! vesicle-mediated transport is_a: GO:0032940 ! secretion by cell intersection_of: GO:0006810 ! transport intersection_of: RO:0002608 GO:0070382 ! process has causal agent exocytic vesicle relationship: BFO:0000051 GO:0099500 ! has part vesicle fusion to plasma membrane relationship: RO:0002608 GO:0070382 ! process has causal agent exocytic vesicle [Term] id: GO:0006892 name: post-Golgi vesicle-mediated transport namespace: biological_process def: "The directed movement of substances from the Golgi to other parts of the cell, including organelles and the plasma membrane, mediated by small transport vesicles." [GOC:ai, GOC:mah] synonym: "post-Golgi transport" EXACT [] is_a: GO:0048193 ! Golgi vesicle transport [Term] id: GO:0006893 name: Golgi to plasma membrane transport namespace: biological_process def: "The directed movement of substances from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane, where they fuse and release their contents by exocytosis." [ISBN:0716731363] synonym: "Golgi to plasma membrane vesicle-mediated transport" EXACT [] is_a: GO:0006892 ! post-Golgi vesicle-mediated transport is_a: GO:0098876 ! vesicle-mediated transport to the plasma membrane intersection_of: GO:0016192 ! vesicle-mediated transport intersection_of: RO:0002338 GO:0005794 ! has target start location Golgi apparatus intersection_of: RO:0002339 GO:0005886 ! has target end location plasma membrane relationship: RO:0002338 GO:0005794 ! has target start location Golgi apparatus [Term] id: GO:0006896 name: Golgi to vacuole transport namespace: biological_process def: "The directed movement of substances from the Golgi to the vacuole." [GOC:ai] synonym: "Golgi to vacuole vesicle-mediated transport" EXACT [] is_a: GO:0006892 ! post-Golgi vesicle-mediated transport is_a: GO:0007034 ! vacuolar transport intersection_of: GO:0016192 ! vesicle-mediated transport intersection_of: BFO:0000066 GO:0005622 ! occurs in intracellular anatomical structure intersection_of: RO:0002338 GO:0005794 ! has target start location Golgi apparatus intersection_of: RO:0002339 GO:0005773 ! has target end location vacuole relationship: RO:0002338 GO:0005794 ! has target start location Golgi apparatus relationship: RO:0002339 GO:0005773 ! has target end location vacuole [Term] id: GO:0006897 name: endocytosis namespace: biological_process def: "A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a part of the plasma membrane to form a new membrane-bounded vesicle." [GOC:mah, ISBN:0198506732, ISBN:0716731363, Wikipedia:Endocytosis] synonym: "endocytic import into cell" EXACT [] synonym: "vesicle endocytosis" EXACT [] xref: Wikipedia:Endocytosis is_a: GO:0016192 ! vesicle-mediated transport is_a: GO:0098657 ! import into cell relationship: BFO:0000051 GO:0006900 ! has part vesicle budding from membrane relationship: BFO:0000051 GO:0010324 ! has part membrane invagination relationship: RO:0002339 GO:0031410 ! has target end location cytoplasmic vesicle [Term] id: GO:0006900 name: vesicle budding from membrane namespace: biological_process def: "The evagination of a membrane, resulting in formation of a vesicle." [GOC:jid, GOC:tb] synonym: "membrane evagination" EXACT [] synonym: "vesicle biosynthesis" EXACT [] synonym: "vesicle formation" EXACT [] is_a: GO:0016050 ! vesicle organization is_a: GO:0061024 ! membrane organization relationship: BFO:0000050 GO:0016192 ! part of vesicle-mediated transport creation_date: 2013-12-19T15:26:17Z [Term] id: GO:0006903 name: vesicle targeting namespace: biological_process def: "The process in which vesicles are directed to specific destination membranes. Targeting involves coordinated interactions among cytoskeletal elements (microtubules or actin filaments), motor proteins, molecules at the vesicle membrane and target membrane surfaces, and vesicle cargo." [GOC:mah, PMID:17335816] is_a: GO:0009987 ! cellular process relationship: BFO:0000050 GO:0016192 ! part of vesicle-mediated transport relationship: BFO:0000050 GO:0051650 ! part of establishment of vesicle localization [Term] id: GO:0006906 name: vesicle fusion namespace: biological_process def: "Fusion of the membrane of a transport vesicle with its target membrane." [GOC:jid] is_a: GO:0016050 ! vesicle organization is_a: GO:0090174 ! organelle membrane fusion intersection_of: GO:0009987 ! cellular process intersection_of: RO:0012008 GO:0012506 ! results in fusion of vesicle membrane relationship: BFO:0000050 GO:0016192 ! part of vesicle-mediated transport relationship: RO:0012008 GO:0012506 ! results in fusion of vesicle membrane [Term] id: GO:0006909 name: phagocytosis namespace: biological_process def: "A vesicle-mediated transport process that results in the engulfment of external particulate material by phagocytes and their delivery to the lysosome. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles." [ISBN:0198506732] xref: Wikipedia:Phagocytosis is_a: GO:0006897 ! endocytosis [Term] id: GO:0006915 name: apoptotic process namespace: biological_process def: "A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died." [GOC:cjm, GOC:dhl, GOC:ecd, GOC:go_curators, GOC:mtg_apoptosis, GOC:tb, ISBN:0198506732, PMID:18846107, PMID:21494263] synonym: "apoptotic cell death" EXACT [GOC:sl] synonym: "apoptotic programmed cell death" EXACT [] synonym: "programmed cell death by apoptosis" EXACT [] xref: Wikipedia:Apoptosis is_a: GO:0012501 ! programmed cell death relationship: RO:0002160 NCBITaxon:33154 ! only in taxon Opisthokonta relationship: RO:0002162 NCBITaxon:33154 {all_only="true"} ! in taxon Opisthokonta relationship: RO:0002224 GO:0097190 ! starts with apoptotic signaling pathway relationship: RO:0002230 GO:0097194 ! ends with execution phase of apoptosis [Term] id: GO:0006921 name: cellular component disassembly involved in execution phase of apoptosis namespace: biological_process def: "The breakdown of structures such as organelles, proteins, or other macromolecular structures during apoptosis." [GOC:dph, GOC:mah, GOC:mtg_apoptosis, GOC:tb] is_a: GO:0022411 ! cellular component disassembly intersection_of: GO:0022411 ! cellular component disassembly intersection_of: BFO:0000050 GO:0097194 ! part of execution phase of apoptosis relationship: BFO:0000050 GO:0097194 ! part of execution phase of apoptosis [Term] id: GO:0006936 name: muscle contraction namespace: biological_process def: "A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis." [GOC:ef, GOC:mtg_muscle, ISBN:0198506732] xref: Wikipedia:Muscle_contraction is_a: GO:0003012 ! muscle system process relationship: BFO:0000066 UBERON:0002385 ! occurs in muscle tissue [Term] id: GO:0006937 name: regulation of muscle contraction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of muscle contraction." [GOC:go_curators] is_a: GO:0090257 ! regulation of muscle system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006936 ! regulates (processual) muscle contraction relationship: RO:0002211 GO:0006936 ! regulates (processual) muscle contraction [Term] id: GO:0006939 name: smooth muscle contraction namespace: biological_process def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length." [GOC:ef, GOC:jl, GOC:mtg_muscle, ISBN:0198506732] synonym: "visceral muscle contraction" EXACT [] is_a: GO:0006936 ! muscle contraction intersection_of: GO:0006936 ! muscle contraction intersection_of: BFO:0000066 UBERON:0001135 ! occurs in smooth muscle tissue relationship: BFO:0000066 UBERON:0001135 ! occurs in smooth muscle tissue [Term] id: GO:0006940 name: regulation of smooth muscle contraction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of smooth muscle contraction." [GOC:go_curators] is_a: GO:0006937 ! regulation of muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006939 ! regulates (processual) smooth muscle contraction relationship: RO:0002211 GO:0006939 ! regulates (processual) smooth muscle contraction [Term] id: GO:0006941 name: striated muscle contraction namespace: biological_process def: "A process in which force is generated within striated muscle tissue, resulting in the shortening of the muscle. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Striated muscle is a type of muscle in which the repeating units (sarcomeres) of the contractile myofibrils are arranged in registry throughout the cell, resulting in transverse or oblique striations observable at the level of the light microscope." [GOC:jl, GOC:mtg_muscle, ISBN:0198506732] synonym: "sarcomeric muscle contraction" EXACT [] is_a: GO:0006936 ! muscle contraction relationship: BFO:0000066 UBERON:0002036 ! occurs in striated muscle tissue [Term] id: GO:0006942 name: regulation of striated muscle contraction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of striated muscle contraction." [GOC:go_curators] is_a: GO:0006937 ! regulation of muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006941 ! regulates (processual) striated muscle contraction relationship: RO:0002211 GO:0006941 ! regulates (processual) striated muscle contraction [Term] id: GO:0006949 name: syncytium formation namespace: biological_process def: "The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane. Syncytia are normally derived from single cells that fuse or fail to complete cell division." [ISBN:0198506732] is_a: GO:0009987 ! cellular process is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 CL:0000228 ! results in formation of anatomical entity multinucleate cell relationship: RO:0002297 CL:0000228 ! results in formation of anatomical entity multinucleate cell [Term] id: GO:0006950 name: response to stress namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." [GOC:mah] is_a: GO:0050896 ! response to stimulus [Term] id: GO:0006952 name: defense response namespace: biological_process def: "Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack." [GOC:go_curators] synonym: "defence response" EXACT [] synonym: "physiological defense response" EXACT [] is_a: GO:0006950 ! response to stress [Term] id: GO:0006954 name: inflammatory response namespace: biological_process def: "The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages." [GO_REF:0000022, ISBN:0198506732] xref: Wikipedia:Inflammation is_a: GO:0006952 ! defense response relationship: RO:0002160 NCBITaxon:7742 ! only in taxon Vertebrata relationship: RO:0002162 NCBITaxon:7742 {all_only="true"} ! in taxon Vertebrata [Term] id: GO:0006955 name: immune response namespace: biological_process def: "Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat." [GO_REF:0000022, GOC:add] is_a: GO:0002376 ! immune system process is_a: GO:0050896 ! response to stimulus [Term] id: GO:0006996 name: organelle organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane." [GOC:mah] synonym: "organelle organisation" EXACT [] synonym: "single organism organelle organization" EXACT [GOC:TermGenie] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0043226 ! results in organization of organelle relationship: RO:0002592 GO:0043226 ! results in organization of organelle creation_date: 2013-12-19T15:25:51Z [Term] id: GO:0006997 name: nucleus organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus." [GOC:dph, GOC:ems, GOC:jl, GOC:mah] synonym: "nuclear organisation" EXACT [] synonym: "nuclear organization" EXACT [] is_a: GO:0006996 ! organelle organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0005634 ! results in organization of nucleus relationship: RO:0002592 GO:0005634 ! results in organization of nucleus [Term] id: GO:0006998 name: nuclear envelope organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope." [GOC:dph, GOC:ems, GOC:jl, GOC:mah] synonym: "nuclear envelope organisation" EXACT [GOC:mah] is_a: GO:0061024 ! membrane organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0005635 ! results in organization of nuclear envelope relationship: BFO:0000050 GO:0006997 ! part of nucleus organization relationship: BFO:0000050 GO:0010256 ! part of endomembrane system organization relationship: RO:0002592 GO:0005635 ! results in organization of nuclear envelope [Term] id: GO:0007000 name: nucleolus organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleolus." [GOC:dph, GOC:jid, GOC:jl, GOC:mah] synonym: "nucleolus organisation" EXACT [] is_a: GO:0006997 ! nucleus organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0005730 ! results in organization of nucleolus relationship: RO:0002592 GO:0005730 ! results in organization of nucleolus [Term] id: GO:0007009 name: plasma membrane organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane." [GOC:dph, GOC:jl, GOC:mah] synonym: "plasma membrane organisation" EXACT [] is_a: GO:0061024 ! membrane organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0005886 ! results in organization of plasma membrane relationship: BFO:0000050 GO:0010256 ! part of endomembrane system organization relationship: RO:0002592 GO:0005886 ! results in organization of plasma membrane [Term] id: GO:0007010 name: cytoskeleton organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures." [GOC:dph, GOC:jl, GOC:mah] synonym: "cytoskeleton organisation" EXACT [] is_a: GO:0006996 ! organelle organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0005856 ! results in organization of cytoskeleton relationship: RO:0002592 GO:0005856 ! results in organization of cytoskeleton [Term] id: GO:0007015 name: actin filament organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking." [GOC:mah] synonym: "actin filament organisation" EXACT [] is_a: GO:0097435 ! supramolecular fiber organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0005884 ! results in organization of actin filament relationship: BFO:0000050 GO:0030036 ! part of actin cytoskeleton organization relationship: RO:0002592 GO:0005884 ! results in organization of actin filament [Term] id: GO:0007017 name: microtubule-based process namespace: biological_process def: "Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins." [GOC:mah] is_a: GO:0009987 ! cellular process intersection_of: GO:0009987 ! cellular process intersection_of: RO:0002608 GO:0005874 ! process has causal agent microtubule relationship: RO:0002608 GO:0005874 ! process has causal agent microtubule [Term] id: GO:0007018 name: microtubule-based movement namespace: biological_process def: "A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules." [GOC:cjm, ISBN:0815316194] is_a: GO:0007017 ! microtubule-based process [Term] id: GO:0007019 name: microtubule depolymerization namespace: biological_process def: "The removal of tubulin heterodimers from one or both ends of a microtubule." [ISBN:0815316194] synonym: "microtubule disassembly" EXACT [] synonym: "microtubule shortening" EXACT [] is_a: GO:0031109 ! microtubule polymerization or depolymerization is_a: GO:0051261 ! protein depolymerization is_a: GO:0097435 ! supramolecular fiber organization intersection_of: GO:0022411 ! cellular component disassembly intersection_of: RO:0002590 GO:0005874 ! results in disassembly of microtubule relationship: RO:0002590 GO:0005874 ! results in disassembly of microtubule [Term] id: GO:0007020 name: microtubule nucleation namespace: biological_process def: "The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation)." [GOC:go_curators, ISBN:0815316194, PMID:12517712] xref: Wikipedia:Microtubule_nucleation is_a: GO:0000226 ! microtubule cytoskeleton organization relationship: BFO:0000050 GO:0046785 ! part of microtubule polymerization [Term] id: GO:0007026 name: negative regulation of microtubule depolymerization namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol." [GOC:mah, ISBN:0815316194] synonym: "down regulation of microtubule depolymerization" EXACT [] synonym: "down-regulation of microtubule depolymerization" EXACT [] synonym: "downregulation of microtubule depolymerization" EXACT [] synonym: "microtubule stabilization" EXACT [] synonym: "negative regulation of microtubule disassembly" EXACT [] is_a: GO:0031111 ! negative regulation of microtubule polymerization or depolymerization is_a: GO:0031114 ! regulation of microtubule depolymerization is_a: GO:1901880 ! negative regulation of protein depolymerization is_a: GO:1902904 ! negative regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007019 ! negatively regulates microtubule depolymerization relationship: RO:0002212 GO:0007019 ! negatively regulates microtubule depolymerization [Term] id: GO:0007027 name: negative regulation of axonemal microtubule depolymerization namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the depolymerization of the specialized microtubules of the axoneme." [GOC:dph, GOC:mah] synonym: "axonemal microtubule stabilization" EXACT [] is_a: GO:0007026 ! negative regulation of microtubule depolymerization is_a: GO:0010937 ! regulation of cytoplasmic microtubule depolymerization is_a: GO:0031345 ! negative regulation of cell projection organization is_a: GO:0120035 ! regulation of plasma membrane bounded cell projection organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060404 ! negatively regulates axonemal microtubule depolymerization relationship: RO:0002212 GO:0060404 ! negatively regulates axonemal microtubule depolymerization [Term] id: GO:0007028 name: cytoplasm organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cytoplasm. The cytoplasm is all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." [GOC:curators, GOC:dph, GOC:jl, GOC:mah] synonym: "cytoplasm organisation" EXACT [] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0005737 ! results in organization of cytoplasm relationship: RO:0002592 GO:0005737 ! results in organization of cytoplasm [Term] id: GO:0007030 name: Golgi organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus." [GOC:dph, GOC:jl, GOC:mah] synonym: "Golgi apparatus organization" EXACT [] synonym: "Golgi organisation" EXACT [] is_a: GO:0006996 ! organelle organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0005794 ! results in organization of Golgi apparatus relationship: BFO:0000050 GO:0010256 ! part of endomembrane system organization relationship: RO:0002592 GO:0005794 ! results in organization of Golgi apparatus [Term] id: GO:0007033 name: vacuole organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole." [GOC:mah] synonym: "vacuole organisation" EXACT [] is_a: GO:0006996 ! organelle organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0005773 ! results in organization of vacuole relationship: RO:0002592 GO:0005773 ! results in organization of vacuole [Term] id: GO:0007034 name: vacuolar transport namespace: biological_process def: "The directed movement of substances into, out of or within a vacuole." [GOC:ai] is_a: GO:0046907 ! intracellular transport intersection_of: GO:0046907 ! intracellular transport intersection_of: RO:0002344 GO:0005773 ! results in transport to from or in vacuole relationship: RO:0002344 GO:0005773 ! results in transport to from or in vacuole [Term] id: GO:0007039 name: protein catabolic process in the vacuole namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of a protein in the vacuole, usually by the action of vacuolar proteases." [GOC:mah, GOC:vw] is_a: GO:0030163 ! protein catabolic process intersection_of: GO:0030163 ! protein catabolic process intersection_of: BFO:0000066 GO:0005773 ! occurs in vacuole relationship: BFO:0000066 GO:0005773 ! occurs in vacuole [Term] id: GO:0007043 name: cell-cell junction assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form a junction between cells." [GOC:ai] synonym: "intercellular junction assembly" EXACT [] is_a: GO:0034329 ! cell junction assembly is_a: GO:0045216 ! cell-cell junction organization intersection_of: GO:0034329 ! cell junction assembly intersection_of: RO:0002588 GO:0005911 ! results in assembly of cell-cell junction relationship: RO:0002588 GO:0005911 ! results in assembly of cell-cell junction [Term] id: GO:0007049 name: cell cycle namespace: biological_process def: "The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division." [GOC:go_curators, GOC:mtg_cell_cycle] synonym: "cell-division cycle" EXACT [] xref: Wikipedia:Cell_cycle is_a: GO:0009987 ! cellular process [Term] id: GO:0007059 name: chromosome segregation namespace: biological_process def: "The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles." [GOC:jl, GOC:mah, GOC:mtg_cell_cycle, GOC:vw] synonym: "chromosome division" EXACT [] xref: Wikipedia:Chromosome_segregation is_a: GO:0022402 ! cell cycle process [Term] id: GO:0007076 name: mitotic chromosome condensation namespace: biological_process def: "The cell cycle process in which chromatin structure is compacted prior to and during mitosis in eukaryotic cells." [GOC:mah, ISBN:0815316194] is_a: GO:0030261 ! chromosome condensation is_a: GO:1903047 ! mitotic cell cycle process intersection_of: GO:0030261 ! chromosome condensation intersection_of: BFO:0000050 GO:0000278 ! part of mitotic cell cycle relationship: BFO:0000050 GO:0000070 ! part of mitotic sister chromatid segregation [Term] id: GO:0007077 name: mitotic nuclear membrane disassembly namespace: biological_process def: "The mitotic cell cycle process in which the controlled partial or complete breakdown of the nuclear membranes during occurs during mitosis." [GOC:bf, PMID:32848252] synonym: "mitotic nuclear envelope breakdown" EXACT [] is_a: GO:0051081 ! nuclear membrane disassembly is_a: GO:1903047 ! mitotic cell cycle process intersection_of: GO:0051081 ! nuclear membrane disassembly intersection_of: BFO:0000050 GO:0000278 ! part of mitotic cell cycle [Term] id: GO:0007088 name: regulation of mitotic nuclear division namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mitosis." [GOC:go_curators] synonym: "regulation of mitosis" EXACT [] is_a: GO:0007346 ! regulation of mitotic cell cycle is_a: GO:0010564 ! regulation of cell cycle process is_a: GO:0051783 ! regulation of nuclear division intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0140014 ! regulates (processual) mitotic nuclear division relationship: RO:0002211 GO:0140014 ! regulates (processual) mitotic nuclear division [Term] id: GO:0007097 name: nuclear migration namespace: biological_process def: "The directed movement of the nucleus to a specific location within a cell." [GOC:ai] synonym: "establishment of position of nucleus" EXACT [] synonym: "nuclear movement" EXACT [] synonym: "nuclear positioning" EXACT [] synonym: "nucleus migration" EXACT [] synonym: "nucleus positioning" EXACT [] synonym: "positioning of nucleus" EXACT [] is_a: GO:0046907 ! intracellular transport is_a: GO:0051647 ! nucleus localization is_a: GO:0051656 ! establishment of organelle localization intersection_of: GO:0046907 ! intracellular transport intersection_of: RO:0004009 GO:0005634 ! has primary input nucleus [Term] id: GO:0007113 name: endomitotic cell cycle namespace: biological_process def: "A mitotic cell cycle in which chromosomes are replicated and sister chromatids separate, but spindle formation, nuclear membrane breakdown and nuclear division do not occur, resulting in an increased number of chromosomes in the cell." [GOC:curators, GOC:dos, GOC:expert_vm] xref: Wikipedia:Mitosis#Endomitosis is_a: GO:0000278 ! mitotic cell cycle [Term] id: GO:0007135 name: meiosis II namespace: biological_process def: "The second nuclear division of meiosis, in which the two chromatids in each chromosome are separated, resulting in four daughter nuclei from the two nuclei produced in meiosis II." [GOC:dph, GOC:mah, ISBN:0198547684] synonym: "meiosis II nuclear division" EXACT [] xref: Wikipedia:Meiosis#Meiosis_II is_a: GO:0061983 ! meiosis II cell cycle process is_a: GO:0140013 ! meiotic nuclear division [Term] id: GO:0007140 name: male meiotic nuclear division namespace: biological_process def: "A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline." [GOC:dph, GOC:mah, GOC:vw] is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0140013 ! meiotic nuclear division intersection_of: GO:0000280 ! nuclear division intersection_of: BFO:0000050 GO:0048232 ! part of male gamete generation intersection_of: BFO:0000050 GO:0051321 ! part of meiotic cell cycle relationship: BFO:0000050 GO:0048232 ! part of male gamete generation [Term] id: GO:0007142 name: male meiosis II namespace: biological_process def: "A cell cycle process comprising the steps by which a cell progresses through male meiosis II, the second meiotic division in the male germline." [GOC:dph, GOC:mah] synonym: "male meiosis II nuclear division" EXACT [] is_a: GO:0007135 ! meiosis II is_a: GO:0007140 ! male meiotic nuclear division intersection_of: GO:0007135 ! meiosis II intersection_of: BFO:0000050 GO:0048232 ! part of male gamete generation intersection_of: BFO:0000050 GO:0051321 ! part of meiotic cell cycle [Term] id: GO:0007143 name: female meiotic nuclear division namespace: biological_process def: "A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline." [GOC:dph, GOC:ems, GOC:mah, GOC:vw] is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0140013 ! meiotic nuclear division intersection_of: GO:0000280 ! nuclear division intersection_of: BFO:0000050 GO:0007292 ! part of female gamete generation intersection_of: BFO:0000050 GO:0051321 ! part of meiotic cell cycle relationship: BFO:0000050 GO:0007292 ! part of female gamete generation [Term] id: GO:0007147 name: female meiosis II namespace: biological_process def: "The cell cycle process in which the second meiotic division occurs in the female germline." [GOC:mah] synonym: "female meiosis II nuclear division" EXACT [] is_a: GO:0007135 ! meiosis II is_a: GO:0007143 ! female meiotic nuclear division intersection_of: GO:0007135 ! meiosis II intersection_of: BFO:0000050 GO:0007292 ! part of female gamete generation intersection_of: BFO:0000050 GO:0051321 ! part of meiotic cell cycle [Term] id: GO:0007154 name: cell communication namespace: biological_process def: "Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:mah] xref: Wikipedia:Cell_signaling is_a: GO:0009987 ! cellular process [Term] id: GO:0007155 name: cell adhesion namespace: biological_process def: "The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules." [GOC:hb, GOC:pf] xref: Wikipedia:Cell_adhesion is_a: GO:0009987 ! cellular process creation_date: 2014-04-15T15:59:10Z [Term] id: GO:0007159 name: leukocyte cell-cell adhesion namespace: biological_process def: "The attachment of a leukocyte to another cell via adhesion molecules." [GOC:go_curators] synonym: "leukocyte adhesion" EXACT [] synonym: "leukocyte cell adhesion" EXACT [] is_a: GO:0098609 ! cell-cell adhesion intersection_of: GO:0098609 ! cell-cell adhesion intersection_of: RO:0000057 CL:0000738 ! has participant leukocyte relationship: RO:0000057 CL:0000738 ! has participant leukocyte relationship: RO:0002160 NCBITaxon:7742 ! only in taxon Vertebrata relationship: RO:0002162 NCBITaxon:33208 {all_only="true"} ! in taxon Metazoa relationship: RO:0002162 NCBITaxon:7742 {all_only="true"} ! in taxon Vertebrata [Term] id: GO:0007162 name: negative regulation of cell adhesion namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion." [GOC:go_curators] synonym: "down regulation of cell adhesion" EXACT [] synonym: "down-regulation of cell adhesion" EXACT [] synonym: "downregulation of cell adhesion" EXACT [] is_a: GO:0030155 ! regulation of cell adhesion is_a: GO:0048523 ! negative regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007155 ! negatively regulates cell adhesion relationship: RO:0002212 GO:0007155 ! negatively regulates cell adhesion [Term] id: GO:0007163 name: establishment or maintenance of cell polarity namespace: biological_process def: "Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns." [GOC:mah] is_a: GO:0009987 ! cellular process [Term] id: GO:0007165 name: signal transduction namespace: biological_process def: "The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell." [GOC:go_curators, GOC:mtg_signaling_feb11] xref: Wikipedia:Signal_transduction is_a: GO:0009987 ! cellular process is_a: GO:0050794 ! regulation of cellular process relationship: BFO:0000050 GO:0007154 ! part of cell communication relationship: BFO:0000050 GO:0023052 ! part of signaling relationship: BFO:0000050 GO:0051716 ! part of cellular response to stimulus [Term] id: GO:0007267 name: cell-cell signaling namespace: biological_process def: "Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions." [GOC:dos, GOC:mah] synonym: "cell-cell signalling" EXACT [] is_a: GO:0007154 ! cell communication is_a: GO:0023052 ! signaling [Term] id: GO:0007268 name: chemical synaptic transmission namespace: biological_process def: "The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse." [GOC:jl, MeSH:D009435] xref: Wikipedia:Neurotransmission is_a: GO:0098916 ! anterograde trans-synaptic signaling relationship: RO:0000057 GO:0045202 ! has participant synapse [Term] id: GO:0007269 name: neurotransmitter secretion namespace: biological_process def: "The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium-regulated exocytosis during synaptic transmission." [GOC:dph] synonym: "neurotransmitter release" EXACT [] synonym: "neurotransmitter secretory pathway" EXACT [] is_a: GO:0006836 ! neurotransmitter transport is_a: GO:0051649 ! establishment of localization in cell is_a: GO:0099643 ! signal release from synapse relationship: BFO:0000066 GO:0098793 ! occurs in presynapse [Term] id: GO:0007271 name: synaptic transmission, cholinergic namespace: biological_process def: "The vesicular release of acetylcholine from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse." [GOC:dos, Wikipedia:Cholinergic] synonym: "cholinergic synaptic transmission" EXACT [] is_a: GO:0007268 ! chemical synaptic transmission relationship: RO:0000057 CHEBI:15355 ! has participant acetylcholine [Term] id: GO:0007274 name: neuromuscular synaptic transmission namespace: biological_process def: "The process of synaptic transmission from a neuron to a muscle, across a synapse." [GOC:dos, GOC:jl, MeSH:D009435] is_a: GO:0007268 ! chemical synaptic transmission [Term] id: GO:0007275 name: multicellular organism development namespace: biological_process def: "The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." [GOC:dph, GOC:ems, GOC:isa_complete, GOC:tb] is_a: GO:0032501 ! multicellular organismal process is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002295 UBERON:0000468 ! results in developmental progression of multicellular organism relationship: RO:0002295 UBERON:0000468 ! results in developmental progression of multicellular organism [Term] id: GO:0007276 name: gamete generation namespace: biological_process def: "The generation and maintenance of gametes in a multicellular organism. A gamete is a haploid reproductive cell." [GOC:ems, GOC:mtg_sensu] is_a: GO:0048609 ! multicellular organismal reproductive process relationship: BFO:0000050 GO:0019953 ! part of sexual reproduction [Term] id: GO:0007281 name: germ cell development namespace: biological_process def: "The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism." [GOC:go_curators] synonym: "germ-cell development" EXACT [] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000586 ! results in development of germ cell relationship: BFO:0000050 GO:0007276 ! part of gamete generation relationship: RO:0002296 CL:0000586 ! results in development of germ cell [Term] id: GO:0007283 name: spermatogenesis namespace: biological_process def: "The developmental process by which male germ line stem cells self renew or give rise to successive cell types resulting in the development of a spermatozoa." [GOC:jid, ISBN:9780878933846, PMID:28073824, PMID:30990821] xref: Wikipedia:Spermatogenesis is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0048232 ! male gamete generation [Term] id: GO:0007284 name: spermatogonial cell division namespace: biological_process def: "The mitotic divisions of the primary spermatogonial cell (a primordial male germ cell) to form secondary spermatogonia (primary spermatocytes)." [GOC:bf, GOC:pr, ISBN:0879694238] synonym: "spermatogonium division" EXACT [] is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0051301 ! cell division intersection_of: GO:0051301 ! cell division intersection_of: RO:0004009 CL:0000020 ! has primary input spermatogonium relationship: BFO:0000050 GO:0007283 ! part of spermatogenesis relationship: RO:0004009 CL:0000020 ! has primary input spermatogonium [Term] id: GO:0007285 name: primary spermatocyte growth namespace: biological_process def: "The phase of growth and gene expression that male germ cells undergo as they enter the spermatocyte stage. The cells grow in volume and transcribe most of the gene products needed for the morphological events that follow meiosis." [GOC:jid, ISBN:0879694238] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0048588 ! developmental cell growth intersection_of: GO:0040007 ! growth intersection_of: RO:0002343 CL:0000656 ! results in growth of primary spermatocyte relationship: BFO:0000050 GO:0007283 ! part of spermatogenesis relationship: RO:0002343 CL:0000656 ! results in growth of primary spermatocyte [Term] id: GO:0007286 name: spermatid development namespace: biological_process def: "The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure." [GOC:dph, GOC:go_curators] synonym: "spermatid cell development" EXACT [] synonym: "spermiogenesis" EXACT [] xref: Wikipedia:Spermiogenesis is_a: GO:0007281 ! germ cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000018 ! results in development of spermatid relationship: BFO:0000050 GO:0048515 ! part of spermatid differentiation relationship: RO:0002296 CL:0000018 ! results in development of spermatid [Term] id: GO:0007288 name: sperm axoneme assembly namespace: biological_process def: "The assembly and organization of the sperm flagellar axoneme, the bundle of microtubules and associated proteins that forms the core of the eukaryotic sperm flagellum, and is responsible for movement." [GOC:bf, GOC:cilia, ISBN:0198547684] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0035082 ! axoneme assembly intersection_of: GO:0035082 ! axoneme assembly intersection_of: BFO:0000066 CL:0000019 ! occurs in sperm relationship: BFO:0000050 GO:0120316 ! part of sperm flagellum assembly [Term] id: GO:0007289 name: spermatid nucleus differentiation namespace: biological_process def: "The specialization of the spermatid nucleus during the development of a spermatid into a mature male gamete competent for fertilization." [GOC:bf, GOC:dph, GOC:jl, GOC:mah] synonym: "spermatid nuclear differentiation" EXACT [] is_a: GO:0006997 ! nucleus organization is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism relationship: BFO:0000050 GO:0007286 ! part of spermatid development [Term] id: GO:0007292 name: female gamete generation namespace: biological_process def: "Generation of the female gamete; specialised haploid cells produced by meiosis and along with a male gamete takes part in sexual reproduction." [GOC:dph, ISBN:0198506732] is_a: GO:0007276 ! gamete generation [Term] id: GO:0007293 name: germarium-derived egg chamber formation namespace: biological_process def: "Construction of a stage-1 egg chamber in the anterior part of the germarium, from the progeny of germ-line and somatic stem cells. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, ISBN:0879694238] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis relationship: BFO:0000050 GO:0048477 ! part of oogenesis relationship: RO:0002160 NCBITaxon:6656 ! only in taxon Arthropoda relationship: RO:0002162 NCBITaxon:6656 {all_only="true"} ! in taxon Arthropoda [Term] id: GO:0007308 name: oocyte construction namespace: biological_process def: "The synthesis, deposition, and organization of the materials in a cell of an ovary; where the cell can then undergo meiosis and form an ovum. An example of this is found in Drosophila melanogaster." [GOC:dph, GOC:ems, GOC:mtg_sensu, GOC:tb, ISBN:0198506732] synonym: "oocyte arrangement" EXACT [GOC:dph, GOC:tb] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0048469 ! cell maturation intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002297 CL:0000023 ! results in formation of anatomical entity oocyte relationship: BFO:0000050 GO:0048599 ! part of oocyte development relationship: RO:0002297 CL:0000023 ! results in formation of anatomical entity oocyte [Term] id: GO:0007309 name: oocyte axis specification namespace: biological_process def: "The establishment, maintenance and elaboration of an axis in the oocyte. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, ISBN:0879694238] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0009798 ! axis specification intersection_of: GO:0009798 ! axis specification intersection_of: BFO:0000066 CL:0000023 ! occurs in oocyte relationship: BFO:0000050 GO:0007308 ! part of oocyte construction relationship: BFO:0000066 CL:0000023 ! occurs in oocyte [Term] id: GO:0007314 name: oocyte anterior/posterior axis specification namespace: biological_process def: "Polarization of the oocyte along its anterior-posterior axis. An example of this is found in Drosophila melanogaster." [GOC:dph, GOC:mtg_sensu, GOC:tb, ISBN:0879694238] synonym: "oocyte anterior/posterior axis determination" EXACT [GOC:dph, GOC:tb] is_a: GO:0007309 ! oocyte axis specification is_a: GO:0009948 ! anterior/posterior axis specification intersection_of: GO:0009948 ! anterior/posterior axis specification intersection_of: BFO:0000066 CL:0000023 ! occurs in oocyte relationship: BFO:0000050 GO:0008358 ! part of maternal determination of anterior/posterior axis, embryo [Term] id: GO:0007320 name: insemination namespace: biological_process def: "The introduction of semen or sperm into the genital tract of a female." [ISBN:0582227089] xref: Wikipedia:Insemination is_a: GO:0044703 ! multi-organism reproductive process is_a: GO:0044706 ! multi-multicellular organism process is_a: GO:0048609 ! multicellular organismal reproductive process relationship: BFO:0000050 GO:0007620 ! part of copulation [Term] id: GO:0007338 name: single fertilization namespace: biological_process def: "The union of male and female gametes to form a zygote." [GOC:ems, GOC:mtg_sensu] is_a: GO:0009566 ! fertilization relationship: RO:0002160 NCBITaxon:2759 ! only in taxon Eukaryota relationship: RO:0002162 NCBITaxon:2759 {all_only="true"} ! in taxon Eukaryota [Term] id: GO:0007343 name: egg activation namespace: biological_process def: "The process in which the egg becomes metabolically active, initiates protein and DNA synthesis and undergoes structural changes to its cortex and/or cytoplasm." [GOC:bf, PMID:9630751] xref: Wikipedia:Egg_activation is_a: GO:0001775 ! cell activation is_a: GO:0022414 ! reproductive process intersection_of: GO:0001775 ! cell activation intersection_of: RO:0004009 CL:0000025 ! has primary input egg cell relationship: BFO:0000050 GO:0007338 ! part of single fertilization relationship: RO:0004009 CL:0000025 ! has primary input egg cell [Term] id: GO:0007346 name: regulation of mitotic cell cycle namespace: biological_process def: "Any process that modulates the rate or extent of progress through the mitotic cell cycle." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "mitotic cell cycle modulation" EXACT [] synonym: "mitotic cell cycle regulation" EXACT [] synonym: "modulation of mitotic cell cycle progression" EXACT [] synonym: "regulation of mitotic cell cycle progression" EXACT [] synonym: "regulation of progression through mitotic cell cycle" EXACT [GOC:dph, GOC:tb] is_a: GO:0051726 ! regulation of cell cycle intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0000278 ! regulates (processual) mitotic cell cycle relationship: RO:0002211 GO:0000278 ! regulates (processual) mitotic cell cycle [Term] id: GO:0007350 name: blastoderm segmentation namespace: biological_process def: "The hierarchical steps resulting in the progressive subdivision of the anterior/posterior axis of the embryo." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238] is_a: GO:0009880 ! embryonic pattern specification is_a: GO:0035282 ! segmentation [Term] id: GO:0007351 name: tripartite regional subdivision namespace: biological_process def: "Subdivision of the embryo along the anterior/posterior axis into anterior, posterior and terminal regions." [GOC:dph, GOC:isa_complete, http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238] is_a: GO:0003002 ! regionalization relationship: BFO:0000050 GO:0007350 ! part of blastoderm segmentation [Term] id: GO:0007354 name: zygotic determination of anterior/posterior axis, embryo namespace: biological_process def: "The specification of the anterior/posterior axis of the embryo by products of genes expressed in the zygote; exemplified in insects by the gap genes, pair rule genes and segment polarity gene cascade." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238] is_a: GO:0008595 ! anterior/posterior axis specification, embryo intersection_of: GO:0008595 ! anterior/posterior axis specification, embryo intersection_of: BFO:0000066 CL:0000365 ! occurs in animal zygote relationship: BFO:0000066 CL:0000365 ! occurs in animal zygote [Term] id: GO:0007369 name: gastrulation namespace: biological_process def: "A complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm." [GOC:curators, ISBN:9780878933846] xref: Wikipedia:Gastrulation is_a: GO:0048598 ! embryonic morphogenesis relationship: BFO:0000051 GO:0001705 ! has part ectoderm formation relationship: BFO:0000051 GO:0001706 ! has part endoderm formation relationship: BFO:0000051 GO:0001707 ! has part mesoderm formation [Term] id: GO:0007389 name: pattern specification process namespace: biological_process def: "Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate." [GOC:go_curators, GOC:isa_complete, ISBN:0521436125] is_a: GO:0032501 ! multicellular organismal process relationship: BFO:0000050 GO:0007275 ! part of multicellular organism development [Term] id: GO:0007398 name: ectoderm development namespace: biological_process def: "The process whose specific outcome is the progression of the ectoderm over time, from its formation to the mature structure. In animal embryos, the ectoderm is the outer germ layer of the embryo, formed during gastrulation." [GOC:dph, GOC:tb] is_a: GO:0009888 ! tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000924 ! results in development of ectoderm relationship: RO:0002296 UBERON:0000924 ! results in development of ectoderm [Term] id: GO:0007399 name: nervous system development namespace: biological_process def: "The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state." [GOC:dgh] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001016 ! results in development of nervous system relationship: RO:0002296 UBERON:0001016 ! results in development of nervous system [Term] id: GO:0007405 name: neuroblast proliferation namespace: biological_process def: "The expansion of a neuroblast population by cell division. A neuroblast is any cell that will divide and give rise to a neuron." [GOC:ai, GOC:mtg_sensu, GOC:sart] is_a: GO:0061351 ! neural precursor cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000031 ! acts on population of neuroblast (sensu Vertebrata) relationship: BFO:0000050 GO:0048699 ! part of generation of neurons relationship: RO:0002160 NCBITaxon:33208 ! only in taxon Metazoa relationship: RO:0002162 NCBITaxon:33208 {all_only="true"} ! in taxon Metazoa relationship: RO:0012003 CL:0000031 ! acts on population of neuroblast (sensu Vertebrata) [Term] id: GO:0007406 name: negative regulation of neuroblast proliferation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the proliferation of neuroblasts." [GOC:ai] synonym: "down regulation of neuroblast proliferation" EXACT [] synonym: "down-regulation of neuroblast proliferation" EXACT [] synonym: "downregulation of neuroblast proliferation" EXACT [] synonym: "suppression of neuroblast proliferation" EXACT [] is_a: GO:0050768 ! negative regulation of neurogenesis is_a: GO:1902692 ! regulation of neuroblast proliferation is_a: GO:2000178 ! negative regulation of neural precursor cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007405 ! negatively regulates neuroblast proliferation relationship: RO:0002212 GO:0007405 ! negatively regulates neuroblast proliferation [Term] id: GO:0007407 name: neuroblast activation namespace: biological_process def: "A change in the morphology or behavior of a neuroblast resulting from exposure to an activating factor such as a cellular or soluble ligand." [GOC:go_curators, GOC:mtg_sensu] is_a: GO:0001775 ! cell activation intersection_of: GO:0001775 ! cell activation intersection_of: RO:0004009 CL:0000031 ! has primary input neuroblast (sensu Vertebrata) relationship: BFO:0000050 GO:0048699 ! part of generation of neurons relationship: RO:0002162 NCBITaxon:33208 {all_only="true"} ! in taxon Metazoa relationship: RO:0004009 CL:0000031 ! has primary input neuroblast (sensu Vertebrata) [Term] id: GO:0007416 name: synapse assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional)." [GOC:mah] synonym: "synapse biogenesis" EXACT [GOC:mah] synonym: "synaptogenesis" EXACT [GOC:mah] xref: Wikipedia:Synaptogenesis is_a: GO:0034329 ! cell junction assembly is_a: GO:0050808 ! synapse organization intersection_of: GO:0009987 ! cellular process intersection_of: RO:0002588 GO:0045202 ! results in assembly of synapse relationship: BFO:0000050 GO:0007399 ! part of nervous system development relationship: RO:0002588 GO:0045202 ! results in assembly of synapse [Term] id: GO:0007417 name: central nervous system development namespace: biological_process def: "The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord." [GOC:bf, GOC:jid, ISBN:0582227089] synonym: "CNS development" EXACT [] xref: Wikipedia:Neural_development is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001017 ! results in development of central nervous system relationship: BFO:0000050 GO:0007399 ! part of nervous system development relationship: RO:0002296 UBERON:0001017 ! results in development of central nervous system [Term] id: GO:0007420 name: brain development namespace: biological_process def: "The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)." [GOC:dph, GOC:jid, GOC:tb, UBERON:0000955] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000955 ! results in development of brain relationship: BFO:0000050 GO:0007417 ! part of central nervous system development relationship: BFO:0000050 GO:0060322 ! part of head development relationship: RO:0002296 UBERON:0000955 ! results in development of brain [Term] id: GO:0007422 name: peripheral nervous system development namespace: biological_process def: "The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands." [GOC:go_curators, UBERON:0000010] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000010 ! results in development of peripheral nervous system relationship: BFO:0000050 GO:0007399 ! part of nervous system development relationship: RO:0002296 UBERON:0000010 ! results in development of peripheral nervous system [Term] id: GO:0007423 name: sensory organ development namespace: biological_process def: "The process whose specific outcome is the progression of sensory organs over time, from its formation to the mature structure." [GOC:go_curators] synonym: "sense organ development" EXACT [GOC:dph] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000020 ! results in development of sense organ relationship: RO:0002296 UBERON:0000020 ! results in development of sense organ [Term] id: GO:0007439 name: ectodermal digestive tract development namespace: biological_process def: "The process whose specific outcome is the progression of the ectodermal digestive tract over time, from its formation to the mature structure. The ectodermal digestive tract includes those portions that are derived from ectoderm." [GOC:curators] is_a: GO:0048729 ! tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002297 UBERON:0004906 ! results in formation of anatomical entity ectodermal part of digestive tract relationship: BFO:0000050 GO:0048565 ! part of digestive tract development relationship: RO:0002297 UBERON:0004906 ! results in formation of anatomical entity ectodermal part of digestive tract [Term] id: GO:0007440 name: foregut morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the foregut are generated and organized." [GOC:jid] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001041 ! results in morphogenesis of foregut relationship: BFO:0000050 GO:0048546 ! part of digestive tract morphogenesis relationship: RO:0002298 UBERON:0001041 ! results in morphogenesis of foregut [Term] id: GO:0007442 name: hindgut morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the hindgut are generated and organized." [GOC:jid] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001046 ! results in morphogenesis of hindgut relationship: BFO:0000050 GO:0048546 ! part of digestive tract morphogenesis relationship: BFO:0000050 GO:0061525 ! part of hindgut development relationship: RO:0002298 UBERON:0001046 ! results in morphogenesis of hindgut [Term] id: GO:0007492 name: endoderm development namespace: biological_process def: "The process whose specific outcome is the progression of the endoderm over time, from its formation to the mature structure. The endoderm is the innermost germ layer that develops into the gastrointestinal tract, the lungs and associated tissues." [GOC:dph, GOC:tb] is_a: GO:0009888 ! tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000925 ! results in development of endoderm relationship: RO:0002296 UBERON:0000925 ! results in development of endoderm [Term] id: GO:0007494 name: midgut development namespace: biological_process def: "The process whose specific outcome is the progression of the midgut over time, from its formation to the mature structure. The midgut is the middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine." [GOC:jid, UBERON:0001045] is_a: GO:0048565 ! digestive tract development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001045 ! results in development of midgut relationship: RO:0002296 UBERON:0001045 ! results in development of midgut [Term] id: GO:0007498 name: mesoderm development namespace: biological_process def: "The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue." [GOC:dph, GOC:tb] is_a: GO:0009888 ! tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000926 ! results in development of mesoderm relationship: RO:0002296 UBERON:0000926 ! results in development of mesoderm [Term] id: GO:0007506 name: gonadal mesoderm development namespace: biological_process def: "The process whose specific outcome is the progression of the gonadal mesoderm over time, from its formation to the mature structure. The gonadal mesoderm is the middle layer of the three primary germ layers of the embryo which will go on to form the gonads of the organism." [GOC:ai] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0007498 ! mesoderm development is_a: GO:0060485 ! mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003855 ! results in development of gonad mesenchyme relationship: BFO:0000050 GO:0008406 ! part of gonad development relationship: RO:0002296 UBERON:0003855 ! results in development of gonad mesenchyme [Term] id: GO:0007507 name: heart development namespace: biological_process def: "The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood." [GOC:jid, UBERON:0000948] xref: Wikipedia:Heart_development is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0007100 ! results in development of primary circulatory organ relationship: BFO:0000050 GO:0072359 ! part of circulatory system development relationship: RO:0002296 UBERON:0007100 ! results in development of primary circulatory organ [Term] id: GO:0007517 name: muscle organ development namespace: biological_process def: "The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work." [GOC:jid, ISBN:0198506732] is_a: GO:0048513 ! animal organ development is_a: GO:0061061 ! muscle structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001630 ! results in development of muscle organ relationship: RO:0002296 UBERON:0001630 ! results in development of muscle organ [Term] id: GO:0007519 name: skeletal muscle tissue development namespace: biological_process def: "The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers." [GOC:mtg_muscle] is_a: GO:0014706 ! striated muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001134 ! results in development of skeletal muscle tissue relationship: BFO:0000050 GO:0060538 ! part of skeletal muscle organ development relationship: RO:0002296 UBERON:0001134 ! results in development of skeletal muscle tissue [Term] id: GO:0007525 name: somatic muscle development namespace: biological_process def: "The process whose specific outcome is the progression of the somatic muscle over time, from its formation to the mature structure. Somatic muscles are striated muscle structures that connect to the exoskeleton or cuticle." [GOC:jid, GOC:mtg_muscle] is_a: GO:0061061 ! muscle structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0014895 ! results in development of somatic muscle, invertebrate relationship: RO:0002296 UBERON:0014895 ! results in development of somatic muscle, invertebrate [Term] id: GO:0007528 name: neuromuscular junction development namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction." [GOC:mtg_OBO2OWL_2013] synonym: "neuromuscular junction organization" EXACT [] is_a: GO:0050808 ! synapse organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0031594 ! results in organization of neuromuscular junction relationship: RO:0002592 GO:0031594 ! results in organization of neuromuscular junction [Term] id: GO:0007548 name: sex differentiation namespace: biological_process def: "The establishment of the sex of an organism by physical differentiation." [GOC:ai] xref: Wikipedia:Sexual_differentiation is_a: GO:0003006 ! developmental process involved in reproduction [Term] id: GO:0007562 name: eclosion namespace: biological_process def: "The emergence of an adult insect from a pupa case." [GOC:dgh, GOC:dos, GOC:mah, ISBN:0198600461] xref: Wikipedia:Pupa#Emergence is_a: GO:0071684 ! organism emergence from protective structure relationship: BFO:0000050 GO:0007275 ! part of multicellular organism development [Term] id: GO:0007563 name: regulation of eclosion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the emergence of an insect from a pupa-case or of a larva from an egg." [GOC:go_curators, ISBN:0198600461] is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007562 ! regulates (processual) eclosion relationship: RO:0002211 GO:0007562 ! regulates (processual) eclosion [Term] id: GO:0007565 name: female pregnancy namespace: biological_process def: "The set of physiological processes that allow an embryo or foetus to develop within the body of a female animal. It covers the time from fertilization of a female ovum by a male spermatozoon until birth." [ISBN:0192800825] synonym: "gestation" EXACT [] xref: Wikipedia:Gestation is_a: GO:0044703 ! multi-organism reproductive process is_a: GO:0044706 ! multi-multicellular organism process relationship: RO:0002160 NCBITaxon:40674 ! only in taxon Mammalia relationship: RO:0002162 NCBITaxon:40674 {all_only="true"} ! in taxon Mammalia [Term] id: GO:0007566 name: embryo implantation namespace: biological_process def: "Attachment of the blastocyst to the uterine lining." [GOC:isa_complete, http://www.medterms.com] synonym: "blastocyst implantation" EXACT [] is_a: GO:0022414 ! reproductive process relationship: BFO:0000050 GO:0007275 ! part of multicellular organism development relationship: BFO:0000050 GO:0007565 ! part of female pregnancy [Term] id: GO:0007585 name: respiratory gaseous exchange by respiratory system namespace: biological_process def: "The process of gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms." [ISBN:0198506732] is_a: GO:0032501 ! multicellular organismal process [Term] id: GO:0007586 name: digestion namespace: biological_process def: "The whole of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." [GOC:isa_complete, ISBN:0198506732] xref: Wikipedia:Digestion is_a: GO:0032501 ! multicellular organismal process [Term] id: GO:0007588 name: excretion namespace: biological_process def: "The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds." [ISBN:0192801023] xref: Wikipedia:Excretion is_a: GO:0003008 ! system process [Term] id: GO:0007589 name: body fluid secretion namespace: biological_process def: "The controlled release of a fluid by a cell or tissue in an animal." [GOC:ai, GOC:dph, GOC:mah, GOC:tb] is_a: GO:0046903 ! secretion is_a: GO:0050878 ! regulation of body fluid levels [Term] id: GO:0007591 name: molting cycle, chitin-based cuticle namespace: biological_process def: "The periodic shedding of part or all of a chitin-based cuticle, which is then replaced by a new cuticle. An example of this is found in Drosophila melanogaster." [GOC:jl, GOC:mtg_sensu] synonym: "chitin-based cuticle molting cycle" EXACT [GOC:dph, GOC:tb] is_a: GO:0042303 ! molting cycle relationship: RO:0002160 NCBITaxon:6656 ! only in taxon Arthropoda relationship: RO:0002162 NCBITaxon:6656 {all_only="true"} ! in taxon Arthropoda [Term] id: GO:0007600 name: sensory perception namespace: biological_process def: "The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." [GOC:ai, GOC:dph] xref: Wikipedia:Perception is_a: GO:0050877 ! nervous system process [Term] id: GO:0007601 name: visual perception namespace: biological_process def: "The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image." [GOC:ai] synonym: "sense of sight" EXACT [] synonym: "sensory visual perception" EXACT [] synonym: "vision" EXACT [] xref: Wikipedia:Visual_perception is_a: GO:0050953 ! sensory perception of light stimulus [Term] id: GO:0007605 name: sensory perception of sound namespace: biological_process def: "The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound." [GOC:ai] synonym: "hearing" EXACT [] synonym: "perception of sound" EXACT [] xref: Wikipedia:Hearing_(sense) is_a: GO:0050954 ! sensory perception of mechanical stimulus [Term] id: GO:0007606 name: sensory perception of chemical stimulus namespace: biological_process def: "The series of events required for an organism to receive a sensory chemical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." [GOC:ai] synonym: "chemosensory perception" EXACT [] is_a: GO:0007600 ! sensory perception [Term] id: GO:0007610 name: behavior namespace: biological_process def: "The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity." [GOC:ems, GOC:jl, ISBN:0395448956, PMID:20160973] synonym: "behavioral response to stimulus" EXACT [] synonym: "behaviour" EXACT [] synonym: "behavioural response to stimulus" EXACT [] xref: Wikipedia:Behavior is_a: GO:0032501 ! multicellular organismal process disjoint_from: GO:0032502 ! developmental process relationship: RO:0002160 NCBITaxon:33208 ! only in taxon Metazoa relationship: RO:0002162 NCBITaxon:33208 {all_only="true"} ! in taxon Metazoa relationship: RO:0002608 UBERON:0001016 ! process has causal agent nervous system creation_date: 2012-09-20T14:06:08Z [Term] id: GO:0007617 name: mating behavior namespace: biological_process def: "The behavioral interactions between organisms for the purpose of mating, or sexual reproduction resulting in the formation of zygotes." [GOC:ai, GOC:dph] synonym: "mating behaviour" EXACT [] xref: Wikipedia:Mating_behaviour is_a: GO:0019098 ! reproductive behavior [Term] id: GO:0007620 name: copulation namespace: biological_process def: "The act of sexual union between male and female, involving the transfer of sperm." [ISBN:0721662544] is_a: GO:0007617 ! mating behavior [Term] id: GO:0007626 name: locomotory behavior namespace: biological_process def: "The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions." [GOC:dph] synonym: "behavior via locomotion" EXACT [] synonym: "locomotion in response to stimulus" EXACT [] synonym: "locomotory behavioral response to stimulus" EXACT [] synonym: "locomotory behaviour" EXACT [] synonym: "locomotory behavioural response to stimulus" EXACT [] is_a: GO:0007610 ! behavior [Term] id: GO:0008015 name: blood circulation namespace: biological_process def: "The flow of blood through the body of an animal, enabling the transport of nutrients to the tissues and the removal of waste products." [GOC:mtg_heart, ISBN:0192800825] is_a: GO:0003013 ! circulatory system process [Term] id: GO:0008016 name: regulation of heart contraction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process in which the heart decreases in volume in a characteristic way to propel blood through the body." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "regulation of cardiac contraction" EXACT [] is_a: GO:1903522 ! regulation of blood circulation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060047 ! regulates (processual) heart contraction relationship: RO:0002211 GO:0060047 ! regulates (processual) heart contraction [Term] id: GO:0008028 name: monocarboxylic acid transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of monocarboxylic acids from one side of a membrane to the other. A monocarboxylic acid is an organic acid with one COOH group." [GOC:ai] xref: Reactome:R-HSA-429749 "SLC5A8 transports monocarboxylates from extracellular region to cytosol" xref: Reactome:R-HSA-433698 "SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol" xref: Reactome:R-HSA-5624211 "Defective SLC16A1 does not cotransport monocarboxylates, H+ from extracellular region to cytosol" xref: Reactome:R-HSA-9645220 "SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol" is_a: GO:0005342 ! organic acid transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:25384 ! has primary input monocarboxylic acid relationship: BFO:0000050 GO:0015718 ! part of monocarboxylic acid transport relationship: RO:0004009 CHEBI:25384 ! has primary input monocarboxylic acid [Term] id: GO:0008078 name: mesodermal cell migration namespace: biological_process def: "The orderly movement of mesodermal cells from one site to another." [GOC:ascb_2009, GOC:dph, GOC:mah, GOC:sat, GOC:tb, PMID:25119047] synonym: "mesoderm cell migration" EXACT [] is_a: GO:0001667 ! ameboidal-type cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000222 ! results in movement of mesodermal cell relationship: RO:0002565 CL:0000222 ! results in movement of mesodermal cell [Term] id: GO:0008088 name: axo-dendritic transport namespace: biological_process def: "The directed movement of organelles or molecules along microtubules in neuron projections." [ISBN:0815316194] xref: Wikipedia:Axoplasmic_transport is_a: GO:0010970 ! transport along microtubule intersection_of: GO:0046907 ! intracellular transport intersection_of: BFO:0000066 GO:0043005 ! occurs in neuron projection intersection_of: RO:0002341 GO:0005874 ! results in transport along microtubule relationship: BFO:0000066 GO:0043005 ! occurs in neuron projection [Term] id: GO:0008104 name: protein localization namespace: biological_process def: "Any process in which a protein is transported to, or maintained in, a specific location." [GOC:ai] synonym: "cellular protein localisation" EXACT [GOC:mah] synonym: "cellular protein localization" EXACT [] synonym: "protein localisation" EXACT [GOC:mah] is_a: GO:0070727 ! cellular macromolecule localization intersection_of: GO:0051179 ! localization intersection_of: RO:0004009 PR:000000001 ! has primary input protein relationship: RO:0004009 PR:000000001 ! has primary input protein [Term] id: GO:0008150 name: biological_process namespace: biological_process namespace: protein def: "A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence." [GOC:pdt] synonym: "biological process" EXACT [] synonym: "physiological process" EXACT [] xref: Wikipedia:Biological_process is_a: BFO:0000015 ! process creation_date: 2012-09-19T15:05:24Z [Term] id: GO:0008152 name: metabolic process namespace: biological_process namespace: protein def: "A cellular process consisting of the biochemical pathways by which a living organism transforms chemical substances. This includes including anabolism (biosynthetic process) and catabolism (catabolic process). Metabolic processes includes the transformation of small molecules, as well macromolecular processes such as DNA repair and replication, protein synthesis and degradation." [GOC:go_curators, ISBN:0198547684] synonym: "metabolism" EXACT [] xref: Wikipedia:Metabolism is_a: GO:0008150 ! biological_process disjoint_from: GO:0051179 ! localization creation_date: 2012-10-17T15:46:40Z [Term] id: GO:0008202 name: steroid metabolic process namespace: biological_process def: "The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus." [ISBN:0198547684] synonym: "steroid metabolism" EXACT [] xref: Wikipedia:Steroid_metabolism is_a: GO:0006629 ! lipid metabolic process is_a: GO:1901360 ! organic cyclic compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:35341 ! has primary input or output steroid relationship: RO:0004007 CHEBI:35341 ! has primary input or output steroid [Term] id: GO:0008206 name: bile acid metabolic process namespace: biological_process def: "The chemical reactions and pathways involving bile acids, a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine." [GOC:go_curators] synonym: "bile acid metabolism" EXACT [] is_a: GO:0008202 ! steroid metabolic process is_a: GO:0032787 ! monocarboxylic acid metabolic process is_a: GO:1901615 ! organic hydroxy compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:36235 ! has primary input or output bile acid anion relationship: RO:0004007 CHEBI:36235 ! has primary input or output bile acid anion [Term] id: GO:0008219 name: cell death namespace: biological_process def: "Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538)." [GOC:mah, GOC:mtg_apoptosis, PMID:25236395] is_a: GO:0009987 ! cellular process [Term] id: GO:0008272 name: sulfate transport namespace: biological_process def: "The directed movement of sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] synonym: "sulphate transport" EXACT [] is_a: GO:0015698 ! inorganic anion transport is_a: GO:0072348 ! sulfur compound transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:16189 ! has primary input sulfate relationship: RO:0004009 CHEBI:16189 ! has primary input sulfate [Term] id: GO:0008283 name: cell population proliferation namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population." [GOC:mah, GOC:mb] is_a: GO:0009987 ! cellular process [Term] id: GO:0008284 name: positive regulation of cell population proliferation namespace: biological_process def: "Any process that activates or increases the rate or extent of cell proliferation." [GOC:go_curators] synonym: "up regulation of cell proliferation" EXACT [] synonym: "up-regulation of cell proliferation" EXACT [] synonym: "upregulation of cell proliferation" EXACT [] is_a: GO:0042127 ! regulation of cell population proliferation is_a: GO:0048522 ! positive regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0008283 ! positively regulates cell population proliferation relationship: RO:0002213 GO:0008283 ! positively regulates cell population proliferation [Term] id: GO:0008285 name: negative regulation of cell population proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of cell proliferation." [GOC:go_curators] synonym: "down regulation of cell proliferation" EXACT [] synonym: "down-regulation of cell proliferation" EXACT [] synonym: "downregulation of cell proliferation" EXACT [] is_a: GO:0042127 ! regulation of cell population proliferation is_a: GO:0048523 ! negative regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0008283 ! negatively regulates cell population proliferation relationship: RO:0002212 GO:0008283 ! negatively regulates cell population proliferation [Term] id: GO:0008291 name: acetylcholine metabolic process namespace: biological_process def: "The chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." [GOC:jl, GOC:nln, ISBN:0192800752] synonym: "acetylcholine metabolism" EXACT [] is_a: GO:0006807 ! nitrogen compound metabolic process is_a: GO:1900619 ! acetate ester metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:15355 ! has primary input or output acetylcholine relationship: RO:0004007 CHEBI:15355 ! has primary input or output acetylcholine [Term] id: GO:0008292 name: acetylcholine biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of acetylcholine, the acetic acid ester of the organic base choline." [GOC:jl, ISBN:0192800752] synonym: "acetylcholine anabolism" EXACT [] synonym: "acetylcholine biosynthesis" EXACT [] synonym: "acetylcholine formation" EXACT [] synonym: "acetylcholine synthesis" EXACT [] is_a: GO:0008291 ! acetylcholine metabolic process is_a: GO:1900620 ! acetate ester biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:15355 ! has primary output acetylcholine relationship: RO:0004008 CHEBI:15355 ! has primary output acetylcholine [Term] id: GO:0008320 name: protein transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of a protein from one side of a membrane to the other." [GOC:jl] xref: Reactome:R-HSA-1268022 "TOMM40 complex translocates proteins from the cytosol to the mitochondrial intermembrane space" xref: Reactome:R-HSA-1299475 "TIMM23 PAM translocates proteins from the mitochondrial intermembrane space to the mitochondrial matrix" xref: Reactome:R-HSA-184269 "Monoubiquitinated N-myristoyl GAG polyprotein is targeted to the late endosomal vesicle membrane by the ESCRT-I complex" xref: Reactome:R-HSA-3149434 "Transport of GAG to the Plasma Membrane" xref: Reactome:R-HSA-5205661 "Pink1 is recruited from the cytoplasm to the mitochondria" xref: Reactome:R-HSA-5210943 "pagA(197-794):ANTRX2 oligomer transports cya and lef (target cell endosome to cytosol)" xref: Reactome:R-HSA-5210947 "pagA(197-794):ANTRX1 oligomer transports cya and lef (target cell endosome to cytosol)" xref: Reactome:R-HSA-5228406 "tetX HC transports tetX LC from target cell endosome membrane into cytosol" xref: Reactome:R-HSA-5229111 "AP4 transports APP from trans-Golgi network to endosome lumen" xref: Reactome:R-HSA-5244404 "botB HC transports botB LC from target cell synaptic vesicle membrane into cytosol" xref: Reactome:R-HSA-5244428 "botA HC transports botA LC from target cell synaptic vesicle membrane into cytosol" xref: Reactome:R-HSA-5244506 "botE HC transports botE LC from target cell synaptic vesicle membrane into cytosol" xref: Reactome:R-HSA-5246514 "botC HC transports botC LC from target cell synaptic vesicle membrane to cytosol" xref: Reactome:R-HSA-5250616 "botD HC transports botD LC from target cell synaptic vesicle membrane into cytosol" xref: Reactome:R-HSA-5250884 "botF HC transports botF LC from target cell synaptic vesicle membrane into cytosol" xref: Reactome:R-HSA-5250972 "botG HC transports botG LC from target cell synaptic vesicle membrane into cytosol" xref: Reactome:R-HSA-5336420 "DT fragment B transports DT fragment A from target cell endosome membrane" xref: Reactome:R-HSA-9636375 "SecA2 transports SapM from cytoplasm to cytosol" xref: Reactome:R-HSA-9698930 "HCMV C Nucleocapsid Translocation" xref: Reactome:R-HSA-9698933 "HCMV B Nucleocapsid Translocation" is_a: GO:0022857 ! transmembrane transporter activity is_a: GO:0140318 ! protein transporter activity intersection_of: GO:0005215 ! transporter activity intersection_of: RO:0002342 GO:0016020 ! results in transport across membrane intersection_of: RO:0004009 PR:000000001 ! has primary input protein relationship: BFO:0000050 GO:0071806 ! part of protein transmembrane transport [Term] id: GO:0008324 name: monoatomic cation transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of cation from one side of a membrane to the other." [GOC:dgf, GOC:mtg_transport, ISBN:0815340729] synonym: "transmembrane cation transporter activity" EXACT [] is_a: GO:0015075 ! monoatomic ion transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:23906 ! has primary input monoatomic cation relationship: BFO:0000050 GO:0098655 ! part of monoatomic cation transmembrane transport relationship: RO:0004009 CHEBI:23906 ! has primary input monoatomic cation [Term] id: GO:0008347 name: glial cell migration namespace: biological_process def: "The orderly movement of a glial cell, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system." [GOC:jl, GOC:mtg_sensu] synonym: "glia cell migration" EXACT [] is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000125 ! results in movement of glial cell relationship: BFO:0000050 GO:0042063 ! part of gliogenesis relationship: RO:0002160 NCBITaxon:33208 ! only in taxon Metazoa relationship: RO:0002162 NCBITaxon:33208 {all_only="true"} ! in taxon Metazoa relationship: RO:0002565 CL:0000125 ! results in movement of glial cell [Term] id: GO:0008354 name: germ cell migration namespace: biological_process def: "The orderly movement of a cell specialized to produce haploid gametes through the embryo from its site of production to the place where the gonads will form." [GOC:bf, GOC:jl] synonym: "germ-cell migration" EXACT [] is_a: GO:0016477 ! cell migration is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000586 ! results in movement of germ cell relationship: BFO:0000050 GO:0007276 ! part of gamete generation relationship: RO:0002565 CL:0000586 ! results in movement of germ cell [Term] id: GO:0008356 name: asymmetric cell division namespace: biological_process def: "The asymmetric division of cells to produce two daughter cells with different developmental potentials. It is of fundamental significance for the generation of cell diversity." [PMID:11672519] synonym: "asymmetrical cell division" EXACT [] xref: Wikipedia:Asymmetric_cell_division is_a: GO:0051301 ! cell division [Term] id: GO:0008358 name: maternal determination of anterior/posterior axis, embryo namespace: biological_process def: "The specification of the anterior/posterior axis of the embryo by gradients of maternally-transcribed gene products; exemplified in insects by the morphogens, bicoid and nanos." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238] is_a: GO:0008595 ! anterior/posterior axis specification, embryo [Term] id: GO:0008406 name: gonad development namespace: biological_process def: "The process whose specific outcome is the progression of the gonad over time, from its formation to the mature structure. The gonad is an animal organ that produces gametes; in some species it also produces hormones." [GOC:ems, ISBN:0198506732] synonym: "gonadogenesis" EXACT [GOC:cjm] is_a: GO:0048513 ! animal organ development is_a: GO:0048608 ! reproductive structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000991 ! results in development of gonad relationship: BFO:0000050 GO:0045137 ! part of development of primary sexual characteristics relationship: RO:0002296 UBERON:0000991 ! results in development of gonad [Term] id: GO:0008504 name: monoamine transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), from one side of a membrane to the other." [GOC:mah] xref: Reactome:R-HSA-372542 "Loading of dopamine into synaptic veiscles" xref: Reactome:R-HSA-379393 "SLC6A3 cotransports DA, Na+ from extracellular region to cytosol" xref: Reactome:R-HSA-380586 "loading of Serotonin in synaptic vesicles" xref: Reactome:R-HSA-380620 "Reuptake of serotonin from the synapse" xref: Reactome:R-HSA-444160 "VMAT1/2 can mediate the transport of biogenic amines" xref: Reactome:R-HSA-5660706 "Defective SLC6A3 does not cotransport DA, Na+ from extracellular region to cytosol" is_a: GO:0022804 ! active transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:63534 ! has primary input monoamine relationship: BFO:0000050 GO:0015844 ! part of monoamine transport relationship: RO:0004009 CHEBI:63534 ! has primary input monoamine [Term] id: GO:0008514 name: organic anion transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of organic anions from one side of a membrane to the other. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage." [GOC:ai] xref: Reactome:R-HSA-2142859 "Growing HA is extruded from the cell by ABCC5" xref: Reactome:R-HSA-561041 "OAT1-3 transport organic anions with antiport of dicarboxylic acids" xref: Reactome:R-HSA-9794830 "SLC22A8 transports Cipro into renal cell" is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:25696 ! has primary input organic anion relationship: BFO:0000050 GO:0015711 ! part of organic anion transport relationship: RO:0004009 CHEBI:25696 ! has primary input organic anion [Term] id: GO:0008544 name: epidermis development namespace: biological_process def: "The process whose specific outcome is the progression of the epidermis over time, from its formation to the mature structure. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species." [GOC:go_curators, UBERON:0001003] is_a: GO:0009888 ! tissue development [Term] id: GO:0008584 name: male gonad development namespace: biological_process def: "The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure." [GOC:jid] synonym: "testicular development" EXACT [GOC:sl] synonym: "testis development" EXACT [GOC:sl] is_a: GO:0008406 ! gonad development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000473 ! results in development of testis relationship: BFO:0000050 GO:0046546 ! part of development of primary male sexual characteristics relationship: RO:0002296 UBERON:0000473 ! results in development of testis [Term] id: GO:0008585 name: female gonad development namespace: biological_process def: "The process whose specific outcome is the progression of the female gonad over time, from its formation to the mature structure." [GOC:dph, GOC:jid, GOC:tb] is_a: GO:0008406 ! gonad development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000992 ! results in development of ovary relationship: BFO:0000050 GO:0046545 ! part of development of primary female sexual characteristics relationship: RO:0002296 UBERON:0000992 ! results in development of ovary [Term] id: GO:0008594 name: photoreceptor cell morphogenesis namespace: biological_process def: "The process in which the structures of a photoreceptor cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a photoreceptor cell, a sensory cell that reacts to the presence of light. An example of this is found in Drosophila melanogaster." [GOC:jid, GOC:mah] is_a: GO:0048667 ! cell morphogenesis involved in neuron differentiation intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 CL:0000210 ! results in morphogenesis of photoreceptor cell relationship: BFO:0000050 GO:0042461 ! part of photoreceptor cell development relationship: RO:0002298 CL:0000210 ! results in morphogenesis of photoreceptor cell [Term] id: GO:0008595 name: anterior/posterior axis specification, embryo namespace: biological_process def: "The specification of the anterior/posterior axis of the embryo by the products of genes expressed maternally and genes expressed in the zygote." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238] is_a: GO:0000578 ! embryonic axis specification is_a: GO:0009948 ! anterior/posterior axis specification relationship: BFO:0000050 GO:0007351 ! part of tripartite regional subdivision [Term] id: GO:0008610 name: lipid biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent." [GOC:go_curators] synonym: "lipid anabolism" EXACT [] synonym: "lipid biosynthesis" EXACT [] synonym: "lipid formation" EXACT [] synonym: "lipid synthesis" EXACT [] synonym: "lipogenesis" EXACT [GOC:sl] is_a: GO:0006629 ! lipid metabolic process is_a: GO:1901576 ! organic substance biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:18059 ! has primary output lipid relationship: RO:0004008 CHEBI:18059 ! has primary output lipid [Term] id: GO:0008643 name: carbohydrate transport namespace: biological_process def: "The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are a group of organic compounds based of the general formula Cx(H2O)y." [GOC:ai] is_a: GO:0071702 ! organic substance transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:16646 ! has primary input carbohydrate relationship: RO:0004009 CHEBI:16646 ! has primary input carbohydrate [Term] id: GO:0008645 name: hexose transmembrane transport namespace: biological_process def: "The process in which hexose is transported across a membrane. Hexoses are aldoses with a chain of six carbon atoms in the molecule." [GOC:vw] is_a: GO:0015749 ! monosaccharide transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002342 GO:0016020 ! results in transport across membrane intersection_of: RO:0004009 CHEBI:18133 ! has primary input hexose relationship: RO:0004009 CHEBI:18133 ! has primary input hexose creation_date: 2010-04-08T10:27:23Z [Term] id: GO:0008652 name: amino acid biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents." [ISBN:0198506732] synonym: "amino acid anabolism" EXACT [] synonym: "amino acid biosynthesis" EXACT [] synonym: "amino acid formation" EXACT [] synonym: "amino acid synthesis" EXACT [] synonym: "cellular amino acid biosynthetic process" EXACT [] xref: Wikipedia:Amino_acid_synthesis is_a: GO:0046394 ! carboxylic acid biosynthetic process is_a: GO:1901566 ! organonitrogen compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:37022 ! has primary output amino-acid anion relationship: RO:0004008 CHEBI:37022 ! has primary output amino-acid anion [Term] id: GO:0009056 name: catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism." [ISBN:0198547684] synonym: "breakdown" EXACT [] synonym: "catabolism" EXACT [] synonym: "degradation" EXACT [] xref: Wikipedia:Catabolism is_a: GO:0008152 ! metabolic process creation_date: 2012-10-17T15:52:35Z [Term] id: GO:0009057 name: macromolecule catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:mah] synonym: "biopolymer catabolic process" EXACT [GOC:mtg_chebi_dec09] synonym: "macromolecule breakdown" EXACT [] synonym: "macromolecule catabolism" EXACT [] synonym: "macromolecule degradation" EXACT [] is_a: GO:0043170 ! macromolecule metabolic process is_a: GO:1901575 ! organic substance catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:33694 ! has primary input biomacromolecule relationship: RO:0004009 CHEBI:33694 ! has primary input biomacromolecule [Term] id: GO:0009058 name: biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones." [GOC:curators, ISBN:0198547684] synonym: "anabolism" EXACT [] synonym: "biosynthesis" EXACT [] synonym: "synthesis" EXACT [] xref: Wikipedia:Anabolism is_a: GO:0008152 ! metabolic process creation_date: 2012-10-17T15:52:18Z [Term] id: GO:0009059 name: macromolecule biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:mah] synonym: "biopolymer biosynthetic process" EXACT [GOC:mtg_chebi_dec09] synonym: "macromolecule anabolism" EXACT [] synonym: "macromolecule biosynthesis" EXACT [] synonym: "macromolecule formation" EXACT [] synonym: "macromolecule synthesis" EXACT [] is_a: GO:0043170 ! macromolecule metabolic process is_a: GO:0044249 ! cellular biosynthetic process is_a: GO:1901576 ! organic substance biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:33694 ! has primary output biomacromolecule relationship: RO:0004008 CHEBI:33694 ! has primary output biomacromolecule [Term] id: GO:0009063 name: amino acid catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents." [GOC:ai] synonym: "amino acid breakdown" EXACT [] synonym: "amino acid catabolism" EXACT [] synonym: "amino acid degradation" EXACT [] synonym: "cellular amino acid catabolic process" EXACT [] is_a: GO:0046395 ! carboxylic acid catabolic process is_a: GO:1901565 ! organonitrogen compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:37022 ! has primary input amino-acid anion relationship: RO:0004009 CHEBI:37022 ! has primary input amino-acid anion [Term] id: GO:0009100 name: glycoprotein metabolic process namespace: biological_process def: "The chemical reactions and pathways involving glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:go_curators, ISBN:0198506732] synonym: "glycoprotein metabolism" EXACT [] is_a: GO:0043170 ! macromolecule metabolic process is_a: GO:1901135 ! carbohydrate derivative metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:17089 ! has primary input or output glycoprotein relationship: RO:0004007 CHEBI:17089 ! has primary input or output glycoprotein [Term] id: GO:0009101 name: glycoprotein biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:go_curators, ISBN:0198506732] synonym: "glycoprotein anabolism" EXACT [] synonym: "glycoprotein biosynthesis" EXACT [] synonym: "glycoprotein formation" EXACT [] synonym: "glycoprotein synthesis" EXACT [] is_a: GO:0009059 ! macromolecule biosynthetic process is_a: GO:0009100 ! glycoprotein metabolic process is_a: GO:1901137 ! carbohydrate derivative biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:17089 ! has primary output glycoprotein relationship: RO:0004008 CHEBI:17089 ! has primary output glycoprotein [Term] id: GO:0009112 name: nucleobase metabolic process namespace: biological_process def: "The chemical reactions and pathways involving a nucleobase, a nitrogenous base that is a constituent of a nucleic acid, e.g. the purines: adenine, guanine, hypoxanthine, xanthine and the pyrimidines: cytosine, uracil, thymine." [GOC:ma] synonym: "nucleobase metabolism" EXACT [] is_a: GO:0055086 ! nucleobase-containing small molecule metabolic process is_a: GO:1901564 ! organonitrogen compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:18282 ! has primary input or output nucleobase relationship: RO:0004007 CHEBI:18282 ! has primary input or output nucleobase [Term] id: GO:0009250 name: glucan biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues." [GOC:go_curators] synonym: "glucan anabolism" EXACT [] synonym: "glucan biosynthesis" EXACT [] synonym: "glucan formation" EXACT [] synonym: "glucan synthesis" EXACT [] is_a: GO:0000271 ! polysaccharide biosynthetic process is_a: GO:0044042 ! glucan metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:37163 ! has primary output glucan relationship: RO:0004008 CHEBI:37163 ! has primary output glucan [Term] id: GO:0009251 name: glucan catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of glucans, polysaccharides consisting only of glucose residues." [GOC:go_curators] synonym: "glucan breakdown" EXACT [] synonym: "glucan catabolism" EXACT [] synonym: "glucan degradation" EXACT [] is_a: GO:0000272 ! polysaccharide catabolic process is_a: GO:0044042 ! glucan metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:37163 ! has primary input glucan relationship: RO:0004009 CHEBI:37163 ! has primary input glucan [Term] id: GO:0009306 name: protein secretion namespace: biological_process def: "The controlled release of proteins from a cell." [GOC:ai] is_a: GO:0015031 ! protein transport is_a: GO:0032940 ! secretion by cell is_a: GO:0035592 ! establishment of protein localization to extracellular region is_a: GO:0071692 ! protein localization to extracellular region intersection_of: GO:0046903 ! secretion intersection_of: RO:0004009 PR:000000001 ! has primary input protein [Term] id: GO:0009308 name: amine metabolic process namespace: biological_process def: "The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom." [GOC:jl, ISBN:0198506732] synonym: "amine metabolism" EXACT [] synonym: "cellular amine metabolic process" EXACT [] is_a: GO:1901564 ! organonitrogen compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:32952 ! has primary input or output amine relationship: RO:0004007 CHEBI:32952 ! has primary input or output amine creation_date: 2009-07-15T11:55:44Z [Term] id: GO:0009309 name: amine biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom." [GOC:jl, ISBN:0198506732] synonym: "amine anabolism" EXACT [] synonym: "amine biosynthesis" EXACT [] synonym: "amine formation" EXACT [] synonym: "amine synthesis" EXACT [] is_a: GO:0009308 ! amine metabolic process is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process is_a: GO:1901566 ! organonitrogen compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:32952 ! has primary output amine relationship: RO:0004008 CHEBI:32952 ! has primary output amine [Term] id: GO:0009310 name: amine catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom." [GOC:jl, ISBN:0198506732] synonym: "amine breakdown" EXACT [] synonym: "amine catabolism" EXACT [] synonym: "amine degradation" EXACT [] is_a: GO:0009308 ! amine metabolic process is_a: GO:1901565 ! organonitrogen compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:32952 ! has primary input amine relationship: RO:0004009 CHEBI:32952 ! has primary input amine [Term] id: GO:0009314 name: response to radiation namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation." [GOC:jl, Wikipedia:Electromagnetic_radiation] synonym: "response to electromagnetic radiation stimulus" EXACT [] synonym: "response to radiation stimulus" EXACT [] is_a: GO:0009628 ! response to abiotic stimulus [Term] id: GO:0009416 name: response to light stimulus namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light." [GOC:go_curators, ISBN:0582227089] is_a: GO:0009314 ! response to radiation intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:30212 ! has primary input photon relationship: RO:0004009 CHEBI:30212 ! has primary input photon [Term] id: GO:0009566 name: fertilization namespace: biological_process def: "The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy)." [GOC:tb, ISBN:0198506732] synonym: "syngamy" EXACT [] xref: Wikipedia:Fertilisation is_a: GO:0022414 ! reproductive process intersection_of: GO:0022414 ! reproductive process intersection_of: RO:0002297 CL:0010017 ! results in formation of anatomical entity zygote intersection_of: RO:0012008 GO:0043073 ! results in fusion of germ cell nucleus relationship: BFO:0000050 GO:0019953 ! part of sexual reproduction relationship: RO:0002297 CL:0010017 ! results in formation of anatomical entity zygote relationship: RO:0012008 GO:0043073 ! results in fusion of germ cell nucleus [Term] id: GO:0009581 name: detection of external stimulus namespace: biological_process def: "The series of events in which an external stimulus is received by a cell and converted into a molecular signal." [GOC:hb] is_a: GO:0009605 ! response to external stimulus is_a: GO:0051606 ! detection of stimulus [Term] id: GO:0009582 name: detection of abiotic stimulus namespace: biological_process def: "The series of events in which an (non-living) abiotic stimulus is received by a cell and converted into a molecular signal." [GOC:hb] is_a: GO:0009628 ! response to abiotic stimulus is_a: GO:0051606 ! detection of stimulus [Term] id: GO:0009583 name: detection of light stimulus namespace: biological_process def: "The series of events in which a light stimulus (in the form of photons) is received and converted into a molecular signal." [GOC:go_curators] synonym: "detection of light" EXACT [] is_a: GO:0009416 ! response to light stimulus is_a: GO:0009581 ! detection of external stimulus is_a: GO:0009582 ! detection of abiotic stimulus [Term] id: GO:0009584 name: detection of visible light namespace: biological_process def: "The series of events in which a visible light stimulus is received by a cell and converted into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm." [GOC:go_curators, ISBN:0198506732] is_a: GO:0009583 ! detection of light stimulus [Term] id: GO:0009593 name: detection of chemical stimulus namespace: biological_process def: "The series of events in which a chemical stimulus is received by a cell and converted into a molecular signal." [GOC:jl] synonym: "chemoperception" EXACT [] synonym: "detection of chemical substance" EXACT [] is_a: GO:0051606 ! detection of stimulus relationship: BFO:0000050 GO:0042221 ! part of response to chemical [Term] id: GO:0009605 name: response to external stimulus namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus." [GOC:hb] synonym: "response to environmental stimulus" EXACT [] is_a: GO:0050896 ! response to stimulus [Term] id: GO:0009607 name: response to biotic stimulus namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism." [GOC:hb] is_a: GO:0050896 ! response to stimulus [Term] id: GO:0009617 name: response to bacterium namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium." [GOC:hb] synonym: "response to bacteria" EXACT [] is_a: GO:0051707 ! response to other organism intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 NCBITaxon:2 ! has primary input Bacteria relationship: RO:0004009 NCBITaxon:2 ! has primary input Bacteria [Term] id: GO:0009620 name: response to fungus namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a fungus." [GOC:hb] synonym: "response to fungi" EXACT [] is_a: GO:0051707 ! response to other organism intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 NCBITaxon:4751 ! has primary input Fungi relationship: RO:0004009 NCBITaxon:4751 ! has primary input Fungi [Term] id: GO:0009628 name: response to abiotic stimulus namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (not derived from living organisms) stimulus." [GOC:hb] is_a: GO:0050896 ! response to stimulus [Term] id: GO:0009636 name: response to toxic substance namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus." [GOC:lr] is_a: GO:0042221 ! response to chemical [Term] id: GO:0009653 name: anatomical structure morphogenesis namespace: biological_process def: "The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form." [GOC:go_curators, ISBN:0521436125] synonym: "anatomical structure organization" EXACT [] synonym: "morphogenesis" EXACT [] xref: Wikipedia:Morphogenesis is_a: GO:0032502 ! developmental process disjoint_from: GO:0048856 ! anatomical structure development disjoint_from: GO:0071695 ! anatomical structure maturation relationship: BFO:0000050 GO:0048856 ! part of anatomical structure development [Term] id: GO:0009712 name: catechol-containing compound metabolic process namespace: biological_process def: "The chemical reactions and pathways involving a compound containing a pyrocatechol (1,2-benzenediol) nucleus or substituent." [GOC:sm, ISBN:0198547684] is_a: GO:0018958 ! phenol-containing compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:33566 ! has primary input or output catechols relationship: RO:0004007 CHEBI:33566 ! has primary input or output catechols [Term] id: GO:0009713 name: catechol-containing compound biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent." [GOC:go_curators] is_a: GO:0009712 ! catechol-containing compound metabolic process is_a: GO:0046189 ! phenol-containing compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:33566 ! has primary output catechols relationship: RO:0004008 CHEBI:33566 ! has primary output catechols [Term] id: GO:0009719 name: response to endogenous stimulus namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism." [GOC:sm] is_a: GO:0050896 ! response to stimulus [Term] id: GO:0009725 name: response to hormone namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus." [GOC:jl] synonym: "response to hormone stimulus" EXACT [GOC:dos] is_a: GO:0009719 ! response to endogenous stimulus is_a: GO:0010033 ! response to organic substance [Term] id: GO:0009743 name: response to carbohydrate namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus." [GOC:jl] synonym: "response to carbohydrate stimulus" EXACT [GOC:dos] is_a: GO:0010033 ! response to organic substance is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:16646 ! has primary input carbohydrate relationship: RO:0004009 CHEBI:16646 ! has primary input carbohydrate [Term] id: GO:0009746 name: response to hexose namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus." [GOC:jl] synonym: "response to hexose stimulus" EXACT [GOC:dos] is_a: GO:0034284 ! response to monosaccharide intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:18133 ! has primary input hexose relationship: RO:0004009 CHEBI:18133 ! has primary input hexose [Term] id: GO:0009749 name: response to glucose namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus." [GOC:jl] synonym: "response to glucose stimulus" EXACT [GOC:dos] is_a: GO:0009746 ! response to hexose intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:17234 ! has primary input glucose relationship: RO:0004009 CHEBI:17234 ! has primary input glucose [Term] id: GO:0009786 name: regulation of asymmetric cell division namespace: biological_process def: "Any process that modulates the frequency, rate or extent of asymmetric cell division." [GOC:lr] is_a: GO:0051302 ! regulation of cell division intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0008356 ! regulates (processual) asymmetric cell division relationship: RO:0002211 GO:0008356 ! regulates (processual) asymmetric cell division [Term] id: GO:0009790 name: embryo development namespace: biological_process def: "The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant." [GOC:go_curators, GOC:isa_complete, GOC:mtg_sensu] synonym: "embryogenesis" EXACT [] synonym: "embryonal development" EXACT [] xref: Wikipedia:Embryogenesis is_a: GO:0007275 ! multicellular organism development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000922 ! results in development of embryo relationship: RO:0002296 UBERON:0000922 ! results in development of embryo [Term] id: GO:0009791 name: post-embryonic development namespace: biological_process def: "The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development." [GOC:go_curators] is_a: GO:0032501 ! multicellular organismal process relationship: BFO:0000050 GO:0007275 ! part of multicellular organism development [Term] id: GO:0009792 name: embryo development ending in birth or egg hatching namespace: biological_process def: "The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell." [GOC:go_curators, GOC:isa_complete, GOC:mtg_sensu] is_a: GO:0009790 ! embryo development relationship: RO:0002160 NCBITaxon:33208 ! only in taxon Metazoa relationship: RO:0002162 NCBITaxon:33208 {all_only="true"} ! in taxon Metazoa [Term] id: GO:0009798 name: axis specification namespace: biological_process def: "The establishment, maintenance and elaboration of a pattern along a line or around a point." [GOC:dph, GOC:go_curators, GOC:isa_complete] is_a: GO:0007389 ! pattern specification process [Term] id: GO:0009820 name: alkaloid metabolic process namespace: biological_process def: "The chemical reactions and pathways involving alkaloids, nitrogen containing natural products which are not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases)." [GOC:lr, ISBN:0122146743] synonym: "alkaloid metabolism" EXACT [] is_a: GO:1901564 ! organonitrogen compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:22315 ! has primary input or output alkaloid relationship: RO:0004007 CHEBI:22315 ! has primary input or output alkaloid [Term] id: GO:0009821 name: alkaloid biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of alkaloids, nitrogen-containing natural products which are not otherwise classified as nonprotein amino acids, amines, peptides, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones, or primary metabolite (such as purine or pyrimidine bases)." [GOC:lr, ISBN:0122146743] synonym: "alkaloid anabolism" EXACT [] synonym: "alkaloid biosynthesis" EXACT [] synonym: "alkaloid formation" EXACT [] synonym: "alkaloid synthesis" EXACT [] xref: UM-BBD_enzymeID:e0711 is_a: GO:0009820 ! alkaloid metabolic process is_a: GO:0044550 ! secondary metabolite biosynthetic process is_a: GO:1901566 ! organonitrogen compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:22315 ! has primary output alkaloid relationship: RO:0004008 CHEBI:22315 ! has primary output alkaloid [Term] id: GO:0009822 name: alkaloid catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of alkaloids, nitrogen containing natural products not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases)." [GOC:lr, ISBN:0122146743] synonym: "alkaloid breakdown" EXACT [] synonym: "alkaloid catabolism" EXACT [] synonym: "alkaloid degradation" EXACT [] is_a: GO:0009820 ! alkaloid metabolic process is_a: GO:0044270 ! cellular nitrogen compound catabolic process is_a: GO:1901565 ! organonitrogen compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:22315 ! has primary input alkaloid relationship: RO:0004009 CHEBI:22315 ! has primary input alkaloid [Term] id: GO:0009880 name: embryonic pattern specification namespace: biological_process def: "The process that results in the patterns of cell differentiation that will arise in an embryo." [GOC:go_curators, ISBN:0521436125] is_a: GO:0007389 ! pattern specification process relationship: BFO:0000050 GO:0009790 ! part of embryo development [Term] id: GO:0009887 name: animal organ morphogenesis namespace: biological_process def: "Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." [GOC:dgh, GOC:go_curators, ISBN:0471245208, ISBN:0721662544] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000062 ! results in morphogenesis of organ relationship: BFO:0000050 GO:0048513 ! part of animal organ development relationship: RO:0002298 UBERON:0000062 ! results in morphogenesis of organ [Term] id: GO:0009888 name: tissue development namespace: biological_process def: "The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure." [ISBN:0471245208] synonym: "histogenesis" EXACT [] xref: Wikipedia:Histogenesis is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000479 ! results in development of tissue relationship: RO:0002160 NCBITaxon:2759 ! only in taxon Eukaryota relationship: RO:0002162 NCBITaxon:2759 {all_only="true"} ! in taxon Eukaryota relationship: RO:0002296 UBERON:0000479 ! results in development of tissue [Term] id: GO:0009889 name: regulation of biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances." [GOC:go_curators] synonym: "regulation of anabolism" EXACT [] synonym: "regulation of biosynthesis" EXACT [] synonym: "regulation of formation" EXACT [] synonym: "regulation of synthesis" EXACT [] is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0009058 ! regulates (processual) biosynthetic process relationship: RO:0002211 GO:0009058 ! regulates (processual) biosynthetic process [Term] id: GO:0009890 name: negative regulation of biosynthetic process namespace: biological_process def: "Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances." [GOC:go_curators] synonym: "down regulation of biosynthetic process" EXACT [] synonym: "down-regulation of biosynthetic process" EXACT [] synonym: "downregulation of biosynthetic process" EXACT [] synonym: "negative regulation of anabolism" EXACT [] synonym: "negative regulation of biosynthesis" EXACT [] synonym: "negative regulation of formation" EXACT [] synonym: "negative regulation of synthesis" EXACT [] is_a: GO:0009889 ! regulation of biosynthetic process is_a: GO:0009892 ! negative regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0009058 ! negatively regulates biosynthetic process relationship: RO:0002212 GO:0009058 ! negatively regulates biosynthetic process [Term] id: GO:0009891 name: positive regulation of biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances." [GOC:go_curators] synonym: "positive regulation of anabolism" EXACT [] synonym: "positive regulation of biosynthesis" EXACT [] synonym: "positive regulation of formation" EXACT [] synonym: "positive regulation of synthesis" EXACT [] synonym: "up regulation of biosynthetic process" EXACT [] synonym: "up-regulation of biosynthetic process" EXACT [] synonym: "upregulation of biosynthetic process" EXACT [] is_a: GO:0009889 ! regulation of biosynthetic process is_a: GO:0009893 ! positive regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0009058 ! positively regulates biosynthetic process relationship: RO:0002213 GO:0009058 ! positively regulates biosynthetic process [Term] id: GO:0009892 name: negative regulation of metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." [GOC:go_curators] synonym: "down regulation of metabolic process" EXACT [] synonym: "down-regulation of metabolic process" EXACT [] synonym: "downregulation of metabolic process" EXACT [] synonym: "negative regulation of metabolism" EXACT [] synonym: "negative regulation of organismal metabolism" EXACT [] is_a: GO:0019222 ! regulation of metabolic process is_a: GO:0048519 ! negative regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0008152 ! negatively regulates metabolic process relationship: RO:0002212 GO:0008152 ! negatively regulates metabolic process [Term] id: GO:0009893 name: positive regulation of metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." [GOC:go_curators] synonym: "positive regulation of metabolism" EXACT [] synonym: "up regulation of metabolic process" EXACT [] synonym: "up-regulation of metabolic process" EXACT [] synonym: "upregulation of metabolic process" EXACT [] is_a: GO:0019222 ! regulation of metabolic process is_a: GO:0048518 ! positive regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0008152 ! positively regulates metabolic process relationship: RO:0002213 GO:0008152 ! positively regulates metabolic process [Term] id: GO:0009894 name: regulation of catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances." [GOC:go_curators] synonym: "regulation of breakdown" EXACT [] synonym: "regulation of catabolism" EXACT [] synonym: "regulation of degradation" EXACT [] is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0009056 ! regulates (processual) catabolic process relationship: RO:0002211 GO:0009056 ! regulates (processual) catabolic process [Term] id: GO:0009895 name: negative regulation of catabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances." [GOC:go_curators] synonym: "down regulation of catabolic process" EXACT [] synonym: "down-regulation of catabolic process" EXACT [] synonym: "downregulation of catabolic process" EXACT [] synonym: "negative regulation of breakdown" EXACT [] synonym: "negative regulation of catabolism" EXACT [] synonym: "negative regulation of degradation" EXACT [] is_a: GO:0009892 ! negative regulation of metabolic process is_a: GO:0009894 ! regulation of catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0009056 ! negatively regulates catabolic process relationship: RO:0002212 GO:0009056 ! negatively regulates catabolic process [Term] id: GO:0009896 name: positive regulation of catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances." [GOC:go_curators] synonym: "positive regulation of breakdown" EXACT [] synonym: "positive regulation of catabolism" EXACT [] synonym: "positive regulation of degradation" EXACT [] synonym: "up regulation of catabolic process" EXACT [] synonym: "up-regulation of catabolic process" EXACT [] synonym: "upregulation of catabolic process" EXACT [] is_a: GO:0009893 ! positive regulation of metabolic process is_a: GO:0009894 ! regulation of catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0009056 ! positively regulates catabolic process relationship: RO:0002213 GO:0009056 ! positively regulates catabolic process [Term] id: GO:0009913 name: epidermal cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of an epidermal cell, any of the cells making up the epidermis." [GOC:dph, GOC:go_curators, GOC:mtg_sensu, GOC:sdb_2009, GOC:tb] is_a: GO:0030855 ! epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000362 ! results in acquisition of features of epidermal cell relationship: BFO:0000050 GO:0008544 ! part of epidermis development relationship: RO:0002315 CL:0000362 ! results in acquisition of features of epidermal cell [Term] id: GO:0009914 name: hormone transport namespace: biological_process def: "The directed movement of hormones into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:tb] is_a: GO:0006810 ! transport is_a: GO:0010817 ! regulation of hormone levels [Term] id: GO:0009948 name: anterior/posterior axis specification namespace: biological_process def: "The establishment, maintenance and elaboration of the anterior/posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism." [GOC:dph, GOC:go_curators, GOC:tb] is_a: GO:0009798 ! axis specification relationship: BFO:0000050 GO:0009952 ! part of anterior/posterior pattern specification [Term] id: GO:0009952 name: anterior/posterior pattern specification namespace: biological_process def: "The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism." [GOC:dph, GOC:go_curators, GOC:isa_complete, GOC:tb] is_a: GO:0003002 ! regionalization [Term] id: GO:0009966 name: regulation of signal transduction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of signal transduction." [GOC:sm] is_a: GO:0010646 ! regulation of cell communication is_a: GO:0023051 ! regulation of signaling is_a: GO:0048583 ! regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007165 ! regulates (processual) signal transduction relationship: RO:0002211 GO:0007165 ! regulates (processual) signal transduction [Term] id: GO:0009967 name: positive regulation of signal transduction namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of signal transduction." [GOC:sm] synonym: "up regulation of signal transduction" EXACT [] synonym: "up-regulation of signal transduction" EXACT [] synonym: "upregulation of signal transduction" EXACT [] is_a: GO:0009966 ! regulation of signal transduction is_a: GO:0010647 ! positive regulation of cell communication is_a: GO:0023056 ! positive regulation of signaling is_a: GO:0048584 ! positive regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007165 ! positively regulates signal transduction relationship: RO:0002213 GO:0007165 ! positively regulates signal transduction [Term] id: GO:0009968 name: negative regulation of signal transduction namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction." [GOC:sm] synonym: "down regulation of signal transduction" EXACT [] synonym: "down-regulation of signal transduction" EXACT [] synonym: "downregulation of signal transduction" EXACT [] is_a: GO:0009966 ! regulation of signal transduction is_a: GO:0010648 ! negative regulation of cell communication is_a: GO:0023057 ! negative regulation of signaling is_a: GO:0048585 ! negative regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007165 ! negatively regulates signal transduction relationship: RO:0002212 GO:0007165 ! negatively regulates signal transduction [Term] id: GO:0009987 name: cellular process namespace: biological_process def: "Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:go_curators, GOC:isa_complete] synonym: "cell physiology" EXACT [] synonym: "cellular physiological process" EXACT [] is_a: GO:0008150 ! biological_process creation_date: 2012-12-11T16:56:55Z [Term] id: GO:0009994 name: oocyte differentiation namespace: biological_process def: "The process in which a relatively unspecialized immature germ cell acquires the specialized features of a mature female gamete." [GOC:go_curators, GOC:mtg_sensu] synonym: "oocyte cell differentiation" EXACT [] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000023 ! results in acquisition of features of oocyte relationship: BFO:0000050 GO:0048477 ! part of oogenesis relationship: RO:0002315 CL:0000023 ! results in acquisition of features of oocyte [Term] id: GO:0010001 name: glial cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized features of a glial cell." [GOC:go_curators, GOC:mtg_sensu] synonym: "glia cell differentiation" EXACT [] synonym: "neuroglia differentiation" EXACT [] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000125 ! results in acquisition of features of glial cell relationship: BFO:0000050 GO:0042063 ! part of gliogenesis relationship: RO:0002160 NCBITaxon:33208 ! only in taxon Metazoa relationship: RO:0002162 NCBITaxon:33208 {all_only="true"} ! in taxon Metazoa relationship: RO:0002315 CL:0000125 ! results in acquisition of features of glial cell [Term] id: GO:0010002 name: cardioblast differentiation namespace: biological_process def: "The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:go_curators] synonym: "cardiac precursor cell differentiation" EXACT [GOC:mtg_heart] synonym: "cardioblast cell differentiation" EXACT [] is_a: GO:0035051 ! cardiocyte differentiation is_a: GO:0048863 ! stem cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0002664 ! results in acquisition of features of cardioblast relationship: RO:0002315 CL:0002664 ! results in acquisition of features of cardioblast [Term] id: GO:0010032 name: meiotic chromosome condensation namespace: biological_process def: "Compaction of chromatin structure prior to meiosis in eukaryotic cells." [PMID:10072401] synonym: "chromosome condensation involved in meiotic cell cycle" EXACT [GOC:dph, GOC:tb] is_a: GO:0030261 ! chromosome condensation is_a: GO:0070192 ! chromosome organization involved in meiotic cell cycle intersection_of: GO:0030261 ! chromosome condensation intersection_of: BFO:0000050 GO:0051321 ! part of meiotic cell cycle [Term] id: GO:0010033 name: response to organic substance namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus." [GOC:sm, PMID:23356676] is_a: GO:0042221 ! response to chemical intersection_of: GO:0042221 ! response to chemical intersection_of: RO:0004009 CHEBI:50860 ! has primary input organic molecular entity relationship: RO:0004009 CHEBI:50860 ! has primary input organic molecular entity [Term] id: GO:0010034 name: response to acetate namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus." [GOC:sm] is_a: GO:0010033 ! response to organic substance is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:30089 ! has primary input acetate relationship: RO:0004009 CHEBI:30089 ! has primary input acetate [Term] id: GO:0010035 name: response to inorganic substance namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus." [GOC:sm] is_a: GO:0042221 ! response to chemical intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:24835 ! has primary input inorganic molecular entity relationship: RO:0004009 CHEBI:24835 ! has primary input inorganic molecular entity [Term] id: GO:0010038 name: response to metal ion namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus." [GOC:sm] synonym: "response to metal" EXACT [] is_a: GO:0010035 ! response to inorganic substance intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:25213 ! has primary input metal cation relationship: RO:0004009 CHEBI:25213 ! has primary input metal cation [Term] id: GO:0010070 name: zygote asymmetric cell division namespace: biological_process def: "The division of the zygote into two daughter cells that will adopt developmentally distinct potentials." [GOC:tb] is_a: GO:0008356 ! asymmetric cell division intersection_of: GO:0008356 ! asymmetric cell division intersection_of: RO:0004009 CL:0000365 ! has primary input animal zygote relationship: RO:0004009 CL:0000365 ! has primary input animal zygote [Term] id: GO:0010160 name: formation of animal organ boundary namespace: biological_process def: "The regionalization process that specifies animal organ primordium boundaries resulting in a restriction of organogenesis to a limited spatial domain and keeping the organ separate from surrounding tissues." [GOC:dph, GOC:isa_complete, PMID:9611175] synonym: "organ boundary specification" EXACT [] is_a: GO:0003002 ! regionalization is_a: GO:0048859 ! formation of anatomical boundary intersection_of: GO:0048859 ! formation of anatomical boundary intersection_of: BFO:0000066 UBERON:0000062 ! occurs in organ relationship: BFO:0000050 GO:0048645 ! part of animal organ formation relationship: BFO:0000066 UBERON:0000062 ! occurs in organ [Term] id: GO:0010171 name: body morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the soma are generated and organized." [GOC:ems, ISBN:0140512888] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000468 ! results in morphogenesis of multicellular organism relationship: RO:0002298 UBERON:0000468 ! results in morphogenesis of multicellular organism [Term] id: GO:0010200 name: response to chitin namespace: biological_process def: "A process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chitin stimulus." [GOC:sm] is_a: GO:0010243 ! response to organonitrogen compound is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:17029 ! has primary input chitin relationship: RO:0004009 CHEBI:17029 ! has primary input chitin [Term] id: GO:0010243 name: response to organonitrogen compound namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond." [PMID:9869419] synonym: "response to organic nitrogen" EXACT [] is_a: GO:0010033 ! response to organic substance is_a: GO:1901698 ! response to nitrogen compound intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:35352 ! has primary input organonitrogen compound relationship: RO:0004009 CHEBI:35352 ! has primary input organonitrogen compound [Term] id: GO:0010256 name: endomembrane system organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system." [GOC:mah, GOC:sm] synonym: "endomembrane organization" EXACT [] synonym: "endomembrane system organisation" EXACT [GOC:mah] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0012505 ! results in organization of endomembrane system relationship: RO:0002592 GO:0012505 ! results in organization of endomembrane system [Term] id: GO:0010324 name: membrane invagination namespace: biological_process def: "The infolding of a membrane." [GOC:tb] is_a: GO:0061024 ! membrane organization creation_date: 2013-12-02T13:58:34Z [Term] id: GO:0010453 name: regulation of cell fate commitment namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field." [GOC:dph, GOC:tb] is_a: GO:0050793 ! regulation of developmental process is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0045165 ! regulates (processual) cell fate commitment relationship: RO:0002211 GO:0045165 ! regulates (processual) cell fate commitment [Term] id: GO:0010454 name: negative regulation of cell fate commitment namespace: biological_process def: "Any process that stops, prevents or reduces the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field." [GOC:dph, GOC:tb] is_a: GO:0010453 ! regulation of cell fate commitment is_a: GO:0045596 ! negative regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0045165 ! negatively regulates cell fate commitment relationship: RO:0002212 GO:0045165 ! negatively regulates cell fate commitment [Term] id: GO:0010455 name: positive regulation of cell fate commitment namespace: biological_process def: "Any process that activates, maintains or increases the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field." [GOC:dph, GOC:tb] is_a: GO:0010453 ! regulation of cell fate commitment is_a: GO:0045597 ! positive regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0045165 ! positively regulates cell fate commitment relationship: RO:0002213 GO:0045165 ! positively regulates cell fate commitment [Term] id: GO:0010463 name: mesenchymal cell proliferation namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." [GOC:dph, GOC:tb] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0008019 ! acts on population of mesenchymal cell relationship: RO:0012003 CL:0008019 ! acts on population of mesenchymal cell [Term] id: GO:0010464 name: regulation of mesenchymal cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." [GOC:dph, GOC:tb] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0010463 ! regulates (processual) mesenchymal cell proliferation relationship: RO:0002211 GO:0010463 ! regulates (processual) mesenchymal cell proliferation [Term] id: GO:0010467 name: gene expression namespace: biological_process def: "The process in which a gene's sequence is converted into a mature gene product (protein or RNA). This includes the production of an RNA transcript and its processing, as well as translation and maturation for protein-coding genes." [GOC:txnOH-2018, PMID:25934543, PMID:31580950] xref: Wikipedia:Gene_expression is_a: GO:0009059 ! macromolecule biosynthetic process [Term] id: GO:0010468 name: regulation of gene expression namespace: biological_process def: "Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)." [GOC:txnOH-2018] xref: Wikipedia:Regulation_of_gene_expression is_a: GO:0010556 ! regulation of macromolecule biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0010467 ! regulates (processual) gene expression relationship: RO:0002211 GO:0010467 ! regulates (processual) gene expression [Term] id: GO:0010470 name: regulation of gastrulation namespace: biological_process def: "Any process that modulates the rate or extent of gastrulation. Gastrulation is the complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals." [GOC:dph, GOC:tb] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis is_a: GO:0045995 ! regulation of embryonic development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007369 ! regulates (processual) gastrulation relationship: RO:0002211 GO:0007369 ! regulates (processual) gastrulation [Term] id: GO:0010481 name: epidermal cell division namespace: biological_process def: "Any process resulting in the physical partitioning and separation of an epidermal cell, any of the cells making up the epidermis, into daughter cells." [PMID:17450124] is_a: GO:0051301 ! cell division intersection_of: GO:0051301 ! cell division intersection_of: RO:0004009 CL:0000362 ! has primary input epidermal cell relationship: RO:0004009 CL:0000362 ! has primary input epidermal cell [Term] id: GO:0010482 name: regulation of epidermal cell division namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the physical partitioning and separation of an epidermal cell into daughter cells. An epidermal cell is any of the cells that make up the epidermis." [PMID:17450124] is_a: GO:0051302 ! regulation of cell division intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0010481 ! regulates (processual) epidermal cell division relationship: RO:0002211 GO:0010481 ! regulates (processual) epidermal cell division [Term] id: GO:0010496 name: intercellular transport namespace: biological_process def: "The movement of substances between cells." [GOC:dhl] is_a: GO:0006810 ! transport is_a: GO:0009987 ! cellular process intersection_of: GO:0006810 ! transport intersection_of: RO:0002338 CL:0000000 ! has target start location cell intersection_of: RO:0002339 CL:0000000 ! has target end location cell intersection_of: RO:0002342 GO:0005615 ! results in transport across extracellular space relationship: RO:0002338 CL:0000000 ! has target start location cell relationship: RO:0002339 CL:0000000 ! has target end location cell relationship: RO:0002342 GO:0005615 ! results in transport across extracellular space creation_date: 2013-12-19T13:24:56Z [Term] id: GO:0010549 name: regulation of membrane disassembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of membrane disassembly." [GOC:dph, GOC:tb] is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030397 ! regulates (processual) membrane disassembly relationship: RO:0002211 GO:0030397 ! regulates (processual) membrane disassembly [Term] id: GO:0010556 name: regulation of macromolecule biosynthetic process namespace: biological_process def: "Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:dph, GOC:tb] is_a: GO:0031326 ! regulation of cellular biosynthetic process is_a: GO:0060255 ! regulation of macromolecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0009059 ! regulates (processual) macromolecule biosynthetic process relationship: RO:0002211 GO:0009059 ! regulates (processual) macromolecule biosynthetic process [Term] id: GO:0010557 name: positive regulation of macromolecule biosynthetic process namespace: biological_process def: "Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:dph, GOC:tb] is_a: GO:0010556 ! regulation of macromolecule biosynthetic process is_a: GO:0010604 ! positive regulation of macromolecule metabolic process is_a: GO:0031328 ! positive regulation of cellular biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0009059 ! positively regulates macromolecule biosynthetic process relationship: RO:0002213 GO:0009059 ! positively regulates macromolecule biosynthetic process [Term] id: GO:0010558 name: negative regulation of macromolecule biosynthetic process namespace: biological_process def: "Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:dph, GOC:tb] is_a: GO:0010556 ! regulation of macromolecule biosynthetic process is_a: GO:0010605 ! negative regulation of macromolecule metabolic process is_a: GO:0031327 ! negative regulation of cellular biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0009059 ! negatively regulates macromolecule biosynthetic process relationship: RO:0002212 GO:0009059 ! negatively regulates macromolecule biosynthetic process [Term] id: GO:0010559 name: regulation of glycoprotein biosynthetic process namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:dph, GOC:tb] is_a: GO:0010556 ! regulation of macromolecule biosynthetic process is_a: GO:1903018 ! regulation of glycoprotein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0009101 ! regulates (processual) glycoprotein biosynthetic process relationship: RO:0002211 GO:0009101 ! regulates (processual) glycoprotein biosynthetic process [Term] id: GO:0010560 name: positive regulation of glycoprotein biosynthetic process namespace: biological_process def: "Any process that increases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:dph, GOC:tb] is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process is_a: GO:0010559 ! regulation of glycoprotein biosynthetic process is_a: GO:1903020 ! positive regulation of glycoprotein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0009101 ! positively regulates glycoprotein biosynthetic process relationship: RO:0002213 GO:0009101 ! positively regulates glycoprotein biosynthetic process [Term] id: GO:0010561 name: negative regulation of glycoprotein biosynthetic process namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:dph, GOC:tb] is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process is_a: GO:0010559 ! regulation of glycoprotein biosynthetic process is_a: GO:1903019 ! negative regulation of glycoprotein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0009101 ! negatively regulates glycoprotein biosynthetic process relationship: RO:0002212 GO:0009101 ! negatively regulates glycoprotein biosynthetic process [Term] id: GO:0010562 name: positive regulation of phosphorus metabolic process namespace: biological_process def: "Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus." [GOC:dph, GOC:tb] is_a: GO:0031325 ! positive regulation of cellular metabolic process is_a: GO:0051174 ! regulation of phosphorus metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006793 ! positively regulates phosphorus metabolic process relationship: RO:0002213 GO:0006793 ! positively regulates phosphorus metabolic process [Term] id: GO:0010563 name: negative regulation of phosphorus metabolic process namespace: biological_process def: "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus." [GOC:dph, GOC:tb] is_a: GO:0031324 ! negative regulation of cellular metabolic process is_a: GO:0051174 ! regulation of phosphorus metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006793 ! negatively regulates phosphorus metabolic process relationship: RO:0002212 GO:0006793 ! negatively regulates phosphorus metabolic process [Term] id: GO:0010564 name: regulation of cell cycle process namespace: biological_process def: "Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events." [GOC:dph, GOC:tb] is_a: GO:0051726 ! regulation of cell cycle intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0022402 ! regulates (processual) cell cycle process relationship: RO:0002211 GO:0022402 ! regulates (processual) cell cycle process [Term] id: GO:0010565 name: regulation of cellular ketone metabolic process namespace: biological_process def: "Any process that modulates the chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups." [GOC:dph, GOC:tb] is_a: GO:0031323 ! regulation of cellular metabolic process is_a: GO:0062012 ! regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0042180 ! regulates (processual) cellular ketone metabolic process relationship: RO:0002211 GO:0042180 ! regulates (processual) cellular ketone metabolic process [Term] id: GO:0010566 name: regulation of ketone biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a ketone, carried out by individual cells." [GOC:dph, GOC:tb] is_a: GO:0010565 ! regulation of cellular ketone metabolic process is_a: GO:0031326 ! regulation of cellular biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0042181 ! regulates (processual) ketone biosynthetic process relationship: RO:0002211 GO:0042181 ! regulates (processual) ketone biosynthetic process [Term] id: GO:0010567 name: regulation of ketone catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a ketone, carried out by individual cells." [GOC:dph, GOC:tb] is_a: GO:0010565 ! regulation of cellular ketone metabolic process is_a: GO:0031329 ! regulation of cellular catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0042182 ! regulates (processual) ketone catabolic process relationship: RO:0002211 GO:0042182 ! regulates (processual) ketone catabolic process [Term] id: GO:0010594 name: regulation of endothelial cell migration namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010632 ! regulation of epithelial cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0043542 ! regulates (processual) endothelial cell migration relationship: RO:0002211 GO:0043542 ! regulates (processual) endothelial cell migration [Term] id: GO:0010595 name: positive regulation of endothelial cell migration namespace: biological_process def: "Any process that increases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010594 ! regulation of endothelial cell migration is_a: GO:0010634 ! positive regulation of epithelial cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0043542 ! positively regulates endothelial cell migration relationship: RO:0002213 GO:0043542 ! positively regulates endothelial cell migration [Term] id: GO:0010596 name: negative regulation of endothelial cell migration namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010594 ! regulation of endothelial cell migration is_a: GO:0010633 ! negative regulation of epithelial cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0043542 ! negatively regulates endothelial cell migration relationship: RO:0002212 GO:0043542 ! negatively regulates endothelial cell migration [Term] id: GO:0010604 name: positive regulation of macromolecule metabolic process namespace: biological_process def: "Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:dph, GOC:tb] is_a: GO:0009893 ! positive regulation of metabolic process is_a: GO:0060255 ! regulation of macromolecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0043170 ! positively regulates macromolecule metabolic process relationship: RO:0002213 GO:0043170 ! positively regulates macromolecule metabolic process [Term] id: GO:0010605 name: negative regulation of macromolecule metabolic process namespace: biological_process def: "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:dph, GOC:tb] is_a: GO:0009892 ! negative regulation of metabolic process is_a: GO:0060255 ! regulation of macromolecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0043170 ! negatively regulates macromolecule metabolic process relationship: RO:0002212 GO:0043170 ! negatively regulates macromolecule metabolic process [Term] id: GO:0010608 name: post-transcriptional regulation of gene expression namespace: biological_process def: "Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript." [GOC:dph, GOC:tb] synonym: "posttranscriptional regulation of gene expression" EXACT [] is_a: GO:0010468 ! regulation of gene expression [Term] id: GO:0010611 name: regulation of cardiac muscle hypertrophy namespace: biological_process def: "Any process that modulates the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division." [GOC:dph, GOC:tb] is_a: GO:0014743 ! regulation of muscle hypertrophy is_a: GO:0043502 ! regulation of muscle adaptation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003300 ! regulates (processual) cardiac muscle hypertrophy relationship: RO:0002211 GO:0003300 ! regulates (processual) cardiac muscle hypertrophy [Term] id: GO:0010612 name: regulation of cardiac muscle adaptation namespace: biological_process def: "Any process that modulates the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors." [GOC:dph, GOC:tb] is_a: GO:0043502 ! regulation of muscle adaptation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0014887 ! regulates (processual) cardiac muscle adaptation relationship: RO:0002211 GO:0014887 ! regulates (processual) cardiac muscle adaptation [Term] id: GO:0010613 name: positive regulation of cardiac muscle hypertrophy namespace: biological_process def: "Any process that increases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010611 ! regulation of cardiac muscle hypertrophy is_a: GO:0014742 ! positive regulation of muscle hypertrophy intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0003300 ! positively regulates cardiac muscle hypertrophy relationship: RO:0002213 GO:0003300 ! positively regulates cardiac muscle hypertrophy [Term] id: GO:0010614 name: negative regulation of cardiac muscle hypertrophy namespace: biological_process def: "Any process that decreases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010611 ! regulation of cardiac muscle hypertrophy is_a: GO:0014741 ! negative regulation of muscle hypertrophy intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0003300 ! negatively regulates cardiac muscle hypertrophy relationship: RO:0002212 GO:0003300 ! negatively regulates cardiac muscle hypertrophy [Term] id: GO:0010615 name: positive regulation of cardiac muscle adaptation namespace: biological_process def: "Any process that increases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010612 ! regulation of cardiac muscle adaptation is_a: GO:0014744 ! positive regulation of muscle adaptation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0014887 ! positively regulates cardiac muscle adaptation relationship: RO:0002213 GO:0014887 ! positively regulates cardiac muscle adaptation [Term] id: GO:0010616 name: negative regulation of cardiac muscle adaptation namespace: biological_process def: "Any process that decreases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010612 ! regulation of cardiac muscle adaptation is_a: GO:0014745 ! negative regulation of muscle adaptation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0014887 ! negatively regulates cardiac muscle adaptation relationship: RO:0002212 GO:0014887 ! negatively regulates cardiac muscle adaptation [Term] id: GO:0010623 name: programmed cell death involved in cell development namespace: biological_process def: "The activation of endogenous cellular processes that result in the death of a cell as part of its development." [GOC:dph, GOC:mtg_apoptosis, GOC:tb] is_a: GO:0012501 ! programmed cell death is_a: GO:0048869 ! cellular developmental process intersection_of: GO:0012501 ! programmed cell death intersection_of: BFO:0000050 GO:0048468 ! part of cell development relationship: BFO:0000050 GO:0048468 ! part of cell development [Term] id: GO:0010628 name: positive regulation of gene expression namespace: biological_process def: "Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)." [GOC:txnOH-2018] is_a: GO:0010468 ! regulation of gene expression is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0010467 ! positively regulates gene expression relationship: RO:0002213 GO:0010467 ! positively regulates gene expression [Term] id: GO:0010629 name: negative regulation of gene expression namespace: biological_process def: "Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)." [GOC:txnOH-2018] is_a: GO:0010468 ! regulation of gene expression is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0010467 ! negatively regulates gene expression relationship: RO:0002212 GO:0010467 ! negatively regulates gene expression [Term] id: GO:0010631 name: epithelial cell migration namespace: biological_process def: "The orderly movement of an epithelial cell from one site to another, often during the development of a multicellular organism." [GOC:ascb_2009, GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0001667 ! ameboidal-type cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000066 ! results in movement of epithelial cell relationship: BFO:0000050 GO:0090132 ! part of epithelium migration relationship: RO:0002565 CL:0000066 ! results in movement of epithelial cell [Term] id: GO:0010632 name: regulation of epithelial cell migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of epithelial cell migration." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0030334 ! regulation of cell migration is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0010631 ! regulates (processual) epithelial cell migration relationship: RO:0002211 GO:0010631 ! regulates (processual) epithelial cell migration [Term] id: GO:0010633 name: negative regulation of epithelial cell migration namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell migration." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010632 ! regulation of epithelial cell migration is_a: GO:0030336 ! negative regulation of cell migration is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0010631 ! negatively regulates epithelial cell migration relationship: RO:0002212 GO:0010631 ! negatively regulates epithelial cell migration [Term] id: GO:0010634 name: positive regulation of epithelial cell migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of epithelial cell migration." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010632 ! regulation of epithelial cell migration is_a: GO:0030335 ! positive regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0010631 ! positively regulates epithelial cell migration relationship: RO:0002213 GO:0010631 ! positively regulates epithelial cell migration [Term] id: GO:0010638 name: positive regulation of organelle organization namespace: biological_process def: "Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle." [GOC:dph, GOC:tb] synonym: "positive regulation of organelle organisation" EXACT [GOC:mah] is_a: GO:0033043 ! regulation of organelle organization is_a: GO:0051130 ! positive regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006996 ! positively regulates organelle organization relationship: RO:0002213 GO:0006996 ! positively regulates organelle organization [Term] id: GO:0010639 name: negative regulation of organelle organization namespace: biological_process def: "Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle." [GOC:dph, GOC:tb] synonym: "negative regulation of organelle organisation" EXACT [GOC:mah] is_a: GO:0033043 ! regulation of organelle organization is_a: GO:0051129 ! negative regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006996 ! negatively regulates organelle organization relationship: RO:0002212 GO:0006996 ! negatively regulates organelle organization [Term] id: GO:0010646 name: regulation of cell communication namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:dph, GOC:tb] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007154 ! regulates (processual) cell communication relationship: RO:0002211 GO:0007154 ! regulates (processual) cell communication [Term] id: GO:0010647 name: positive regulation of cell communication namespace: biological_process def: "Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:dph, GOC:tb] is_a: GO:0010646 ! regulation of cell communication is_a: GO:0048522 ! positive regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007154 ! positively regulates cell communication relationship: RO:0002213 GO:0007154 ! positively regulates cell communication [Term] id: GO:0010648 name: negative regulation of cell communication namespace: biological_process def: "Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:dph, GOC:tb] is_a: GO:0010646 ! regulation of cell communication is_a: GO:0048523 ! negative regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007154 ! negatively regulates cell communication relationship: RO:0002212 GO:0007154 ! negatively regulates cell communication [Term] id: GO:0010656 name: negative regulation of muscle cell apoptotic process namespace: biological_process def: "Any process that decreases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death." [GOC:dph, GOC:mtg_apoptosis, GOC:tb] is_a: GO:0010660 ! regulation of muscle cell apoptotic process is_a: GO:0043066 ! negative regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0010657 ! negatively regulates muscle cell apoptotic process relationship: RO:0002212 GO:0010657 ! negatively regulates muscle cell apoptotic process [Term] id: GO:0010657 name: muscle cell apoptotic process namespace: biological_process def: "A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a muscle cell and result in its death. A muscle cell is a mature contractile cell, commonly known as a myocyte, that forms one of three kinds of muscle." [CL:0000187, GOC:dph, GOC:mtg_apoptosis, GOC:tb] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000187 ! occurs in muscle cell relationship: BFO:0000066 CL:0000187 ! occurs in muscle cell relationship: RO:0002160 NCBITaxon:33208 ! only in taxon Metazoa relationship: RO:0002162 NCBITaxon:33208 {all_only="true"} ! in taxon Metazoa [Term] id: GO:0010658 name: striated muscle cell apoptotic process namespace: biological_process def: "A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a striated muscle cell and result in its death. Striated muscle cells make up striated muscle fibers which are divided by transverse bands into striations." [CL:0000737, GOC:dph, GOC:mtg_apoptosis, GOC:tb] is_a: GO:0010657 ! muscle cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000737 ! occurs in striated muscle cell relationship: BFO:0000066 CL:0000737 ! occurs in striated muscle cell [Term] id: GO:0010659 name: cardiac muscle cell apoptotic process namespace: biological_process def: "A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a cardiac muscle cell and result in its death. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction." [CL:0000746, GOC:dph, GOC:mtg_apoptosis, GOC:tb] is_a: GO:0010658 ! striated muscle cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000746 ! occurs in cardiac muscle cell relationship: BFO:0000066 CL:0000746 ! occurs in cardiac muscle cell [Term] id: GO:0010660 name: regulation of muscle cell apoptotic process namespace: biological_process def: "Any process that modulates the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death." [GOC:dph, GOC:mtg_apoptosis, GOC:tb] is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0010657 ! regulates (processual) muscle cell apoptotic process relationship: RO:0002211 GO:0010657 ! regulates (processual) muscle cell apoptotic process [Term] id: GO:0010661 name: positive regulation of muscle cell apoptotic process namespace: biological_process def: "Any process that increases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death." [GOC:dph, GOC:mtg_apoptosis, GOC:tb] is_a: GO:0010660 ! regulation of muscle cell apoptotic process is_a: GO:0043065 ! positive regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0010657 ! positively regulates muscle cell apoptotic process relationship: RO:0002213 GO:0010657 ! positively regulates muscle cell apoptotic process [Term] id: GO:0010662 name: regulation of striated muscle cell apoptotic process namespace: biological_process def: "Any process that modulates the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death." [GOC:dph, GOC:mtg_apoptosis, GOC:tb] is_a: GO:0010660 ! regulation of muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0010658 ! regulates (processual) striated muscle cell apoptotic process relationship: RO:0002211 GO:0010658 ! regulates (processual) striated muscle cell apoptotic process [Term] id: GO:0010663 name: positive regulation of striated muscle cell apoptotic process namespace: biological_process def: "Any process that increases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death." [GOC:dph, GOC:mtg_apoptosis, GOC:tb] is_a: GO:0010661 ! positive regulation of muscle cell apoptotic process is_a: GO:0010662 ! regulation of striated muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0010658 ! positively regulates striated muscle cell apoptotic process relationship: RO:0002213 GO:0010658 ! positively regulates striated muscle cell apoptotic process [Term] id: GO:0010664 name: negative regulation of striated muscle cell apoptotic process namespace: biological_process def: "Any process that decreases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death." [GOC:BHF, GOC:dph, GOC:mtg_apoptosis, GOC:rl, GOC:tb] synonym: "down regulation of striated muscle cell apoptosis" EXACT [GOC:dph, GOC:rl, GOC:tb] synonym: "down-regulation of striated muscle cell apoptosis" EXACT [GOC:dph, GOC:rl, GOC:tb] synonym: "downregulation of striated muscle cell apoptosis" EXACT [GOC:dph, GOC:rl, GOC:tb] is_a: GO:0010656 ! negative regulation of muscle cell apoptotic process is_a: GO:0010662 ! regulation of striated muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0010658 ! negatively regulates striated muscle cell apoptotic process relationship: RO:0002212 GO:0010658 ! negatively regulates striated muscle cell apoptotic process [Term] id: GO:0010665 name: regulation of cardiac muscle cell apoptotic process namespace: biological_process def: "Any process that modulates the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death." [GOC:dph, GOC:mtg_apoptosis, GOC:tb] is_a: GO:0010662 ! regulation of striated muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0010659 ! regulates (processual) cardiac muscle cell apoptotic process relationship: RO:0002211 GO:0010659 ! regulates (processual) cardiac muscle cell apoptotic process [Term] id: GO:0010666 name: positive regulation of cardiac muscle cell apoptotic process namespace: biological_process def: "Any process that increases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death." [GOC:dph, GOC:mtg_apoptosis, GOC:tb] is_a: GO:0010663 ! positive regulation of striated muscle cell apoptotic process is_a: GO:0010665 ! regulation of cardiac muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0010659 ! positively regulates cardiac muscle cell apoptotic process relationship: RO:0002213 GO:0010659 ! positively regulates cardiac muscle cell apoptotic process [Term] id: GO:0010667 name: negative regulation of cardiac muscle cell apoptotic process namespace: biological_process def: "Any process that decreases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death." [GOC:BHF, GOC:dph, GOC:mtg_apoptosis, GOC:rl, GOC:tb] synonym: "down regulation of cardiac muscle cell apoptosis" EXACT [GOC:dph, GOC:rl, GOC:tb] synonym: "down-regulation of cardiac muscle cell apoptosis" EXACT [GOC:dph, GOC:rl, GOC:tb] synonym: "downregulation of cardiac muscle cell apoptosis" EXACT [GOC:dph, GOC:rl, GOC:tb] is_a: GO:0010664 ! negative regulation of striated muscle cell apoptotic process is_a: GO:0010665 ! regulation of cardiac muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0010659 ! negatively regulates cardiac muscle cell apoptotic process relationship: RO:0002212 GO:0010659 ! negatively regulates cardiac muscle cell apoptotic process [Term] id: GO:0010668 name: ectodermal cell differentiation namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an ectodermal cell. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GOC:dph, GOC:tb] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000221 ! results in acquisition of features of ectodermal cell relationship: BFO:0000050 GO:0007398 ! part of ectoderm development relationship: RO:0002315 CL:0000221 ! results in acquisition of features of ectodermal cell [Term] id: GO:0010700 name: negative regulation of norepinephrine secretion namespace: biological_process def: "Any process that decreases the frequency, rate or extent of the regulated release of norepinephrine." [GOC:dph, GOC:tb] is_a: GO:0014061 ! regulation of norepinephrine secretion is_a: GO:0033604 ! negative regulation of catecholamine secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048243 ! negatively regulates norepinephrine secretion relationship: RO:0002212 GO:0048243 ! negatively regulates norepinephrine secretion [Term] id: GO:0010701 name: positive regulation of norepinephrine secretion namespace: biological_process def: "Any process that increases the frequency, rate or extent of the regulated release of norepinephrine." [GOC:dph, GOC:tb] is_a: GO:0014061 ! regulation of norepinephrine secretion is_a: GO:0033605 ! positive regulation of catecholamine secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0048243 ! positively regulates norepinephrine secretion relationship: RO:0002213 GO:0048243 ! positively regulates norepinephrine secretion [Term] id: GO:0010710 name: regulation of collagen catabolic process namespace: biological_process def: "Any process that modulates the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix." [GOC:BHF, GOC:dph, GOC:tb] synonym: "regulation of collagen breakdown" EXACT [GOC:dph, GOC:tb] synonym: "regulation of collagen catabolism" EXACT [GOC:dph, GOC:tb] synonym: "regulation of collagen degradation" EXACT [GOC:dph, GOC:tb] is_a: GO:0009894 ! regulation of catabolic process is_a: GO:0010712 ! regulation of collagen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030574 ! regulates (processual) collagen catabolic process relationship: RO:0002211 GO:0030574 ! regulates (processual) collagen catabolic process [Term] id: GO:0010711 name: negative regulation of collagen catabolic process namespace: biological_process def: "Any process that decreases the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix." [GOC:BHF, GOC:dph, GOC:tb] synonym: "down regulation of collagen catabolic process" EXACT [GOC:dph, GOC:tb] synonym: "down-regulation of collagen catabolic process" EXACT [GOC:dph, GOC:tb] synonym: "downregulation of collagen catabolic process" EXACT [GOC:dph, GOC:tb] synonym: "negative regulation of collagen breakdown" EXACT [GOC:dph, GOC:tb] synonym: "negative regulation of collagen catabolism" EXACT [GOC:dph, GOC:tb] synonym: "negative regulation of collagen degradation" EXACT [GOC:dph, GOC:tb] is_a: GO:0009895 ! negative regulation of catabolic process is_a: GO:0010710 ! regulation of collagen catabolic process is_a: GO:0010713 ! negative regulation of collagen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030574 ! negatively regulates collagen catabolic process relationship: RO:0002212 GO:0030574 ! negatively regulates collagen catabolic process [Term] id: GO:0010712 name: regulation of collagen metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." [GOC:dph, GOC:tb] synonym: "regulation of collagen metabolism" EXACT [GOC:dph, GOC:tb] is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0032963 ! regulates (processual) collagen metabolic process relationship: RO:0002211 GO:0032963 ! regulates (processual) collagen metabolic process [Term] id: GO:0010713 name: negative regulation of collagen metabolic process namespace: biological_process def: "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." [GOC:dph, GOC:tb] is_a: GO:0009892 ! negative regulation of metabolic process is_a: GO:0010712 ! regulation of collagen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0032963 ! negatively regulates collagen metabolic process relationship: RO:0002212 GO:0032963 ! negatively regulates collagen metabolic process [Term] id: GO:0010714 name: positive regulation of collagen metabolic process namespace: biological_process def: "Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." [GOC:dph, GOC:tb] synonym: "positive regulation of collagen metabolism" EXACT [GOC:dph, GOC:tb] is_a: GO:0009893 ! positive regulation of metabolic process is_a: GO:0010712 ! regulation of collagen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0032963 ! positively regulates collagen metabolic process relationship: RO:0002213 GO:0032963 ! positively regulates collagen metabolic process [Term] id: GO:0010715 name: regulation of extracellular matrix disassembly namespace: biological_process def: "Any process that modulates the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix." [GOC:BHF, GOC:dph, GOC:tb] synonym: "regulation of extracellular matrix breakdown" EXACT [GOC:dph, GOC:tb] synonym: "regulation of extracellular matrix degradation" EXACT [GOC:dph, GOC:tb] is_a: GO:1903053 ! regulation of extracellular matrix organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0022617 ! regulates (processual) extracellular matrix disassembly relationship: RO:0002211 GO:0022617 ! regulates (processual) extracellular matrix disassembly [Term] id: GO:0010716 name: negative regulation of extracellular matrix disassembly namespace: biological_process def: "Any process that decreases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix." [GOC:BHF, GOC:dph, GOC:tb] synonym: "down regulation of extracellular matrix disassembly" EXACT [GOC:dph, GOC:tb] synonym: "down-regulation of extracellular matrix disassembly" EXACT [GOC:dph, GOC:tb] synonym: "downregulation of extracellular matrix disassembly" EXACT [GOC:dph, GOC:tb] synonym: "negative regulation of extracellular matrix breakdown" EXACT [GOC:dph, GOC:tb] synonym: "negative regulation of extracellular matrix degradation" EXACT [GOC:dph, GOC:tb] is_a: GO:0010715 ! regulation of extracellular matrix disassembly is_a: GO:1903054 ! negative regulation of extracellular matrix organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0022617 ! negatively regulates extracellular matrix disassembly relationship: RO:0002212 GO:0022617 ! negatively regulates extracellular matrix disassembly [Term] id: GO:0010717 name: regulation of epithelial to mesenchymal transition namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001837 ! regulates (processual) epithelial to mesenchymal transition relationship: RO:0002211 GO:0001837 ! regulates (processual) epithelial to mesenchymal transition [Term] id: GO:0010718 name: positive regulation of epithelial to mesenchymal transition namespace: biological_process def: "Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010717 ! regulation of epithelial to mesenchymal transition is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001837 ! positively regulates epithelial to mesenchymal transition relationship: RO:0002213 GO:0001837 ! positively regulates epithelial to mesenchymal transition [Term] id: GO:0010719 name: negative regulation of epithelial to mesenchymal transition namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010717 ! regulation of epithelial to mesenchymal transition is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001837 ! negatively regulates epithelial to mesenchymal transition relationship: RO:0002212 GO:0001837 ! negatively regulates epithelial to mesenchymal transition [Term] id: GO:0010720 name: positive regulation of cell development namespace: biological_process def: "Any process that increases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0060284 ! regulation of cell development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0048468 ! positively regulates cell development relationship: RO:0002213 GO:0048468 ! positively regulates cell development [Term] id: GO:0010721 name: negative regulation of cell development namespace: biological_process def: "Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0060284 ! regulation of cell development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048468 ! negatively regulates cell development relationship: RO:0002212 GO:0048468 ! negatively regulates cell development [Term] id: GO:0010761 name: fibroblast migration namespace: biological_process def: "Cell migration that is accomplished by extension and retraction of a fibroblast pseudopodium. A fibroblast is a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules." [GOC:BHF, GOC:dph, GOC:tb] synonym: "fibroblast cell migration" EXACT [GOC:dph] is_a: GO:0001667 ! ameboidal-type cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000057 ! results in movement of fibroblast relationship: RO:0002565 CL:0000057 ! results in movement of fibroblast [Term] id: GO:0010762 name: regulation of fibroblast migration namespace: biological_process def: "Any process that modulates the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium." [GOC:dph, GOC:tb] synonym: "regulation of fibroblast cell migration" EXACT [GOC:dph] is_a: GO:0030334 ! regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0010761 ! regulates (processual) fibroblast migration relationship: RO:0002211 GO:0010761 ! regulates (processual) fibroblast migration [Term] id: GO:0010763 name: positive regulation of fibroblast migration namespace: biological_process def: "Any process that increases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium." [GOC:BHF, GOC:dph, GOC:tb] synonym: "positive regulation of fibroblast cell migration" EXACT [GOC:dph] is_a: GO:0010762 ! regulation of fibroblast migration is_a: GO:0030335 ! positive regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0010761 ! positively regulates fibroblast migration relationship: RO:0002213 GO:0010761 ! positively regulates fibroblast migration [Term] id: GO:0010764 name: negative regulation of fibroblast migration namespace: biological_process def: "Any process that decreases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium." [GOC:dph, GOC:tb] synonym: "negative regulation of fibroblast cell migration" EXACT [GOC:dph] is_a: GO:0010762 ! regulation of fibroblast migration is_a: GO:0030336 ! negative regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0010761 ! negatively regulates fibroblast migration relationship: RO:0002212 GO:0010761 ! negatively regulates fibroblast migration [Term] id: GO:0010765 name: positive regulation of sodium ion transport namespace: biological_process def: "Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:tb] is_a: GO:0002028 ! regulation of sodium ion transport is_a: GO:0043270 ! positive regulation of monoatomic ion transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006814 ! positively regulates sodium ion transport relationship: RO:0002213 GO:0006814 ! positively regulates sodium ion transport [Term] id: GO:0010766 name: negative regulation of sodium ion transport namespace: biological_process def: "Any process that decreases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:tb] is_a: GO:0002028 ! regulation of sodium ion transport is_a: GO:0043271 ! negative regulation of monoatomic ion transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006814 ! negatively regulates sodium ion transport relationship: RO:0002212 GO:0006814 ! negatively regulates sodium ion transport [Term] id: GO:0010770 name: positive regulation of cell morphogenesis namespace: biological_process def: "Any process that increases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history." [GOC:dph, GOC:tb] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0022604 ! regulation of cell morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0000902 ! positively regulates cell morphogenesis relationship: RO:0002213 GO:0000902 ! positively regulates cell morphogenesis [Term] id: GO:0010771 name: negative regulation of cell morphogenesis namespace: biological_process def: "Any process that decreases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history." [GOC:dph, GOC:tb] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0022604 ! regulation of cell morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0000902 ! negatively regulates cell morphogenesis relationship: RO:0002212 GO:0000902 ! negatively regulates cell morphogenesis [Term] id: GO:0010817 name: regulation of hormone levels namespace: biological_process def: "Any process that modulates the levels of hormone within an organism or a tissue. A hormone is any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action." [GOC:BHF, GOC:dph, GOC:tb] [Term] id: GO:0010827 name: regulation of glucose transmembrane transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:tb] is_a: GO:0034762 ! regulation of transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1904659 ! regulates (processual) glucose transmembrane transport relationship: RO:0002211 GO:1904659 ! regulates (processual) glucose transmembrane transport [Term] id: GO:0010828 name: positive regulation of glucose transmembrane transport namespace: biological_process def: "Any process that increases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010827 ! regulation of glucose transmembrane transport is_a: GO:0034764 ! positive regulation of transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1904659 ! positively regulates glucose transmembrane transport relationship: RO:0002213 GO:1904659 ! positively regulates glucose transmembrane transport [Term] id: GO:0010829 name: negative regulation of glucose transmembrane transport namespace: biological_process def: "Any process that decreases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010827 ! regulation of glucose transmembrane transport is_a: GO:0034763 ! negative regulation of transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1904659 ! negatively regulates glucose transmembrane transport relationship: RO:0002212 GO:1904659 ! negatively regulates glucose transmembrane transport [Term] id: GO:0010830 name: regulation of myotube differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." [GOC:dph, GOC:tb] is_a: GO:0051153 ! regulation of striated muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0014902 ! regulates (processual) myotube differentiation relationship: RO:0002211 GO:0014902 ! regulates (processual) myotube differentiation [Term] id: GO:0010831 name: positive regulation of myotube differentiation namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." [GOC:dph, GOC:tb] is_a: GO:0010830 ! regulation of myotube differentiation is_a: GO:0051155 ! positive regulation of striated muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0014902 ! positively regulates myotube differentiation relationship: RO:0002213 GO:0014902 ! positively regulates myotube differentiation [Term] id: GO:0010832 name: negative regulation of myotube differentiation namespace: biological_process def: "Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." [GOC:dph, GOC:tb] is_a: GO:0010830 ! regulation of myotube differentiation is_a: GO:0051154 ! negative regulation of striated muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0014902 ! negatively regulates myotube differentiation relationship: RO:0002212 GO:0014902 ! negatively regulates myotube differentiation [Term] id: GO:0010842 name: retina layer formation namespace: biological_process def: "The process in which the vertebrate retina is organized into three laminae: the outer nuclear layer (ONL), which contains photoreceptor nuclei; the inner nuclear layer (INL), which contains amacrine, bipolar and horizontal cells; and the retinal ganglion cell (RGC) layer. Between the inner and outer nuclear layers, the outer plexiform layer (OPL) contains connections between the photoreceptors and bipolar and horizontal cells. The inner plexiform layer (IPL) is positioned between the INL and the ganglion cell layer and contains the dendrites of RGCs and processes of bipolar and amacrine cells. Spanning all layers of the retina are the radially oriented Mueller glia." [GOC:ascb_2009, GOC:dph, GOC:tb, PMID:1270266] synonym: "retinal lamination" EXACT [GOC:dph, GOC:tb] synonym: "retinal layer formation" EXACT [GOC:dph, GOC:tb] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0001781 ! results in formation of anatomical entity layer of retina relationship: BFO:0000050 GO:0003407 ! part of neural retina development relationship: BFO:0000050 GO:0060042 ! part of retina morphogenesis in camera-type eye relationship: RO:0002297 UBERON:0001781 ! results in formation of anatomical entity layer of retina [Term] id: GO:0010876 name: lipid localization namespace: biological_process def: "Any process in which a lipid is transported to, or maintained in, a specific location." [GOC:BHF, GOC:dph, GOC:tb] synonym: "lipid localisation" EXACT [GOC:mah] is_a: GO:0033036 ! macromolecule localization intersection_of: GO:0033036 ! macromolecule localization intersection_of: RO:0004009 CHEBI:18059 ! has primary input lipid relationship: RO:0004009 CHEBI:18059 ! has primary input lipid [Term] id: GO:0010893 name: positive regulation of steroid biosynthetic process namespace: biological_process def: "Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus." [GOC:tb] is_a: GO:0045940 ! positive regulation of steroid metabolic process is_a: GO:0046889 ! positive regulation of lipid biosynthetic process is_a: GO:0050810 ! regulation of steroid biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006694 ! positively regulates steroid biosynthetic process relationship: RO:0002213 GO:0006694 ! positively regulates steroid biosynthetic process [Term] id: GO:0010894 name: negative regulation of steroid biosynthetic process namespace: biological_process def: "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus." [GOC:BHF, GOC:tb] is_a: GO:0045939 ! negative regulation of steroid metabolic process is_a: GO:0050810 ! regulation of steroid biosynthetic process is_a: GO:0051055 ! negative regulation of lipid biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006694 ! negatively regulates steroid biosynthetic process relationship: RO:0002212 GO:0006694 ! negatively regulates steroid biosynthetic process [Term] id: GO:0010906 name: regulation of glucose metabolic process namespace: biological_process def: "Any process that modulates the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose." [GOC:BHF, GOC:tb] synonym: "regulation of glucose metabolism" EXACT [GOC:tb] is_a: GO:0006109 ! regulation of carbohydrate metabolic process is_a: GO:0062012 ! regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006006 ! regulates (processual) glucose metabolic process relationship: RO:0002211 GO:0006006 ! regulates (processual) glucose metabolic process [Term] id: GO:0010907 name: positive regulation of glucose metabolic process namespace: biological_process def: "Any process that increases the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose." [GOC:BHF, GOC:tb] synonym: "positive regulation of glucose metabolism" EXACT [GOC:tb] is_a: GO:0010906 ! regulation of glucose metabolic process is_a: GO:0045913 ! positive regulation of carbohydrate metabolic process is_a: GO:0062013 ! positive regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006006 ! positively regulates glucose metabolic process relationship: RO:0002213 GO:0006006 ! positively regulates glucose metabolic process [Term] id: GO:0010927 name: cellular component assembly involved in morphogenesis namespace: biological_process def: "The cellular component assembly that is part of the initial shaping of the component during its developmental progression." [GOC:dph, GOC:tb] is_a: GO:0022607 ! cellular component assembly is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0022607 ! cellular component assembly intersection_of: BFO:0000050 GO:0009653 ! part of anatomical structure morphogenesis relationship: BFO:0000050 GO:0032989 ! part of cellular anatomical entity morphogenesis [Term] id: GO:0010937 name: regulation of cytoplasmic microtubule depolymerization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cytoplasmic microtubule depolymerization." [GOC:dph, GOC:tb] is_a: GO:0031114 ! regulation of microtubule depolymerization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0010938 ! regulates (processual) cytoplasmic microtubule depolymerization relationship: RO:0002211 GO:0010938 ! regulates (processual) cytoplasmic microtubule depolymerization [Term] id: GO:0010938 name: cytoplasmic microtubule depolymerization namespace: biological_process def: "The removal of tubulin heterodimers from one or both ends of a cytoplasmic microtubule." [GOC:dph, GOC:tb] is_a: GO:0007019 ! microtubule depolymerization is_a: GO:0031122 ! cytoplasmic microtubule organization intersection_of: GO:0007019 ! microtubule depolymerization intersection_of: BFO:0000066 GO:0005737 ! occurs in cytoplasm relationship: BFO:0000066 GO:0005737 ! occurs in cytoplasm [Term] id: GO:0010948 name: negative regulation of cell cycle process namespace: biological_process def: "Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events." [GOC:dph, GOC:tb] is_a: GO:0010564 ! regulation of cell cycle process is_a: GO:0045786 ! negative regulation of cell cycle intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0022402 ! negatively regulates cell cycle process relationship: RO:0002212 GO:0022402 ! negatively regulates cell cycle process creation_date: 2009-04-27T09:53:22Z [Term] id: GO:0010959 name: regulation of metal ion transport namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of metal ion transport. Metal ion transport is the directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:tb] is_a: GO:0043269 ! regulation of monoatomic ion transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030001 ! regulates (processual) metal ion transport relationship: RO:0002211 GO:0030001 ! regulates (processual) metal ion transport creation_date: 2009-05-06T11:40:55Z [Term] id: GO:0010962 name: regulation of glucan biosynthetic process namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of glucan biosynthesis. Glucan biosynthetic processes are the chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues." [GOC:dph, GOC:tb] is_a: GO:0032885 ! regulation of polysaccharide biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0009250 ! regulates (processual) glucan biosynthetic process relationship: RO:0002211 GO:0009250 ! regulates (processual) glucan biosynthetic process creation_date: 2009-05-11T12:17:53Z [Term] id: GO:0010966 name: regulation of phosphate transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of phosphate transport. Phosphate transport is the directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:tb] is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006817 ! regulates (processual) phosphate ion transport relationship: RO:0002211 GO:0006817 ! regulates (processual) phosphate ion transport creation_date: 2009-05-20T11:42:50Z [Term] id: GO:0010968 name: regulation of microtubule nucleation namespace: biological_process def: "Any process that modulates the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell." [GOC:dph, GOC:tb] is_a: GO:0031113 ! regulation of microtubule polymerization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007020 ! regulates (processual) microtubule nucleation relationship: RO:0002211 GO:0007020 ! regulates (processual) microtubule nucleation creation_date: 2009-05-20T11:51:21Z [Term] id: GO:0010970 name: transport along microtubule namespace: biological_process def: "The movement of organelles or other particles from one location in the cell to another along microtubules, driven by motor activity." [GOC:dph, GOC:mah, GOC:tb] synonym: "establishment of localization by movement along microtubule" EXACT [GOC:dph] synonym: "movement along microtubule" EXACT [] is_a: GO:0007018 ! microtubule-based movement is_a: GO:0030705 ! cytoskeleton-dependent intracellular transport is_a: GO:0099111 ! microtubule-based transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002341 GO:0005874 ! results in transport along microtubule relationship: RO:0002341 GO:0005874 ! results in transport along microtubule creation_date: 2009-05-27T10:56:08Z [Term] id: GO:0010975 name: regulation of neuron projection development namespace: biological_process def: "Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." [GOC:dph, GOC:tb] is_a: GO:0120035 ! regulation of plasma membrane bounded cell projection organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0031175 ! regulates (processual) neuron projection development relationship: RO:0002211 GO:0031175 ! regulates (processual) neuron projection development creation_date: 2009-06-01T10:44:45Z [Term] id: GO:0010976 name: positive regulation of neuron projection development namespace: biological_process def: "Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." [GOC:dph, GOC:tb] is_a: GO:0010975 ! regulation of neuron projection development is_a: GO:0031346 ! positive regulation of cell projection organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0031175 ! positively regulates neuron projection development relationship: RO:0002213 GO:0031175 ! positively regulates neuron projection development creation_date: 2009-06-01T10:46:44Z [Term] id: GO:0010977 name: negative regulation of neuron projection development namespace: biological_process def: "Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." [GOC:dph, GOC:tb] is_a: GO:0010975 ! regulation of neuron projection development is_a: GO:0031345 ! negative regulation of cell projection organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0031175 ! negatively regulates neuron projection development relationship: RO:0002212 GO:0031175 ! negatively regulates neuron projection development creation_date: 2009-06-01T10:47:42Z [Term] id: GO:0012501 name: programmed cell death namespace: biological_process def: "A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell." [GOC:lr, GOC:mtg_apoptosis] xref: Wikipedia:Programmed_cell_death is_a: GO:0008219 ! cell death intersection_of: GO:0008219 ! cell death intersection_of: RO:0002224 GO:0007165 ! starts with signal transduction relationship: RO:0002224 GO:0007165 ! starts with signal transduction [Term] id: GO:0012505 name: endomembrane system namespace: cellular_component def: "A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles." [GOC:lh] xref: Wikipedia:Endomembrane_system is_a: GO:0110165 ! cellular anatomical entity relationship: BFO:0000050 CL:0000000 ! part of cell relationship: BFO:0000051 GO:0005773 ! has part vacuole relationship: BFO:0000051 GO:0005886 ! has part plasma membrane [Term] id: GO:0012506 name: vesicle membrane namespace: cellular_component def: "The lipid bilayer surrounding any membrane-bounded vesicle in the cell." [GOC:mah, GOC:vesicle] xref: NIF_Subcellular:sao1153182838 is_a: GO:0031090 ! organelle membrane intersection_of: GO:0016020 ! membrane intersection_of: BFO:0000050 GO:0031982 ! part of vesicle relationship: BFO:0000050 GO:0031982 ! part of vesicle [Term] id: GO:0014009 name: glial cell proliferation namespace: biological_process def: "The multiplication or reproduction of glial cells by cell division, resulting in the expansion of their population. Glial cells exist throughout the nervous system, and include Schwann cells, astrocytes, and oligodendrocytes among others." [GOC:ef, ISBN:0878932585] synonym: "glia proliferation" EXACT [] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000125 ! acts on population of glial cell relationship: BFO:0000050 GO:0042063 ! part of gliogenesis relationship: RO:0012003 CL:0000125 ! acts on population of glial cell [Term] id: GO:0014013 name: regulation of gliogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of gliogenesis, the formation of mature glia." [GOC:ef] is_a: GO:0050767 ! regulation of neurogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0042063 ! regulates (processual) gliogenesis relationship: RO:0002211 GO:0042063 ! regulates (processual) gliogenesis [Term] id: GO:0014014 name: negative regulation of gliogenesis namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of gliogenesis, the formation of mature glia." [GOC:ef] synonym: "down regulation of gliogenesis" EXACT [] synonym: "down-regulation of gliogenesis" EXACT [] synonym: "downregulation of gliogenesis" EXACT [] is_a: GO:0014013 ! regulation of gliogenesis is_a: GO:0050768 ! negative regulation of neurogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0042063 ! negatively regulates gliogenesis relationship: RO:0002212 GO:0042063 ! negatively regulates gliogenesis [Term] id: GO:0014015 name: positive regulation of gliogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of gliogenesis, the formation of mature glia." [GOC:ef] synonym: "up regulation of gliogenesis" EXACT [] synonym: "up-regulation of gliogenesis" EXACT [] synonym: "upregulation of gliogenesis" EXACT [] is_a: GO:0014013 ! regulation of gliogenesis is_a: GO:0050769 ! positive regulation of neurogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0042063 ! positively regulates gliogenesis relationship: RO:0002213 GO:0042063 ! positively regulates gliogenesis [Term] id: GO:0014016 name: neuroblast differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a neuroblast. There are at least four stages through which the pluripotent cells of epiblast or blastula become neuroblasts." [GOC:ef, ISBN:0878932585] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000031 ! results in acquisition of features of neuroblast (sensu Vertebrata) relationship: BFO:0000050 GO:0048699 ! part of generation of neurons relationship: RO:0002315 CL:0000031 ! results in acquisition of features of neuroblast (sensu Vertebrata) [Term] id: GO:0014019 name: neuroblast development namespace: biological_process def: "The process aimed at the progression of a neuroblast over time, from initial commitment of the cell to a specific state, to the mature neuroblast. It does not include processes where the neuroblast turns into a glial cell or a neuron." [GOC:ef, ISBN:0878932585] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000031 ! results in development of neuroblast (sensu Vertebrata) relationship: BFO:0000050 GO:0014016 ! part of neuroblast differentiation relationship: RO:0002296 CL:0000031 ! results in development of neuroblast (sensu Vertebrata) [Term] id: GO:0014020 name: primary neural tube formation namespace: biological_process def: "The formation of the neural tube from an epithelial cell sheet (the neuroepithelium or neural plate). In primary neurulation, the cells surrounding the neural plate direct the neural plate cells to proliferate, invaginate, and pinch off from the surface to form a hollow epithelial tube. Primary neurulation is the typical mechanism of formation of the anterior neural tube." [GOC:ef, ISBN:0878932585, PMID:15327780] synonym: "primary neural tube morphogenesis" EXACT [GOC:dph] synonym: "primary neurulation" EXACT [] is_a: GO:0001838 ! embryonic epithelial tube formation relationship: BFO:0000050 GO:0001841 ! part of neural tube formation [Term] id: GO:0014023 name: neural rod formation namespace: biological_process def: "The formation of a solid rod of neurectoderm derived from the neural keel. The neural rod is roughly circular in cross section. Neural rod formation occurs during primary neurulation in teleosts." [GOC:dh, GOC:ef] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0005068 ! results in formation of anatomical entity neural rod relationship: BFO:0000050 GO:0014020 ! part of primary neural tube formation relationship: RO:0002160 NCBITaxon:32443 ! only in taxon Teleostei relationship: RO:0002162 NCBITaxon:32443 {all_only="true"} ! in taxon Teleostei relationship: RO:0002297 UBERON:0005068 ! results in formation of anatomical entity neural rod [Term] id: GO:0014025 name: neural keel formation namespace: biological_process def: "The formation of a thickened region of the neurectoderm that is roughly triangular in cross section. The neural keel develops from the neural plate and develops into the neural rod. Neural keel formation occurs during primary neurulation in teleosts." [GOC:dh, GOC:ef] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0007135 ! results in formation of anatomical entity neural keel relationship: BFO:0000050 GO:0014023 ! part of neural rod formation relationship: RO:0002297 UBERON:0007135 ! results in formation of anatomical entity neural keel [Term] id: GO:0014028 name: notochord formation namespace: biological_process def: "The formation of the notochord from the chordamesoderm. The notochord is composed of large cells packed within a firm connective tissue sheath and is found in all chordates at the ventral surface of the neural tube. In vertebrates, the notochord contributes to the vertebral column." [GOC:dh, GOC:ef] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0002328 ! results in formation of anatomical entity notochord relationship: BFO:0000050 GO:0007399 ! part of nervous system development relationship: BFO:0000050 GO:0048570 ! part of notochord morphogenesis relationship: RO:0002297 UBERON:0002328 ! results in formation of anatomical entity notochord [Term] id: GO:0014029 name: neural crest formation namespace: biological_process def: "The formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes." [GOC:dh, GOC:ef] is_a: GO:0001837 ! epithelial to mesenchymal transition is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0002342 ! results in formation of anatomical entity neural crest relationship: BFO:0000050 GO:0043009 ! part of chordate embryonic development relationship: RO:0002297 UBERON:0002342 ! results in formation of anatomical entity neural crest [Term] id: GO:0014031 name: mesenchymal cell development namespace: biological_process def: "The process aimed at the progression of a mesenchymal cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." [GOC:dh, GOC:ef] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0008019 ! results in development of mesenchymal cell relationship: BFO:0000050 GO:0048762 ! part of mesenchymal cell differentiation relationship: RO:0002296 CL:0008019 ! results in development of mesenchymal cell [Term] id: GO:0014032 name: neural crest cell development namespace: biological_process def: "The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." [GOC:dh, GOC:ef] is_a: GO:0048864 ! stem cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0011012 ! results in development of neural crest cell relationship: BFO:0000050 GO:0014033 ! part of neural crest cell differentiation relationship: RO:0002296 CL:0011012 ! results in development of neural crest cell [Term] id: GO:0014033 name: neural crest cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a neural crest cell." [GOC:dh, GOC:ef] is_a: GO:0048762 ! mesenchymal cell differentiation is_a: GO:0048863 ! stem cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000333 ! results in acquisition of features of migratory neural crest cell relationship: RO:0002315 CL:0000333 ! results in acquisition of features of migratory neural crest cell [Term] id: GO:0014041 name: regulation of neuron maturation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of neuron maturation, the process leading to the attainment of the full functional capacity of a neuron. This process is independent of morphogenetic change." [GOC:ef] is_a: GO:0045664 ! regulation of neuron differentiation is_a: GO:1903429 ! regulation of cell maturation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0042551 ! regulates (processual) neuron maturation relationship: RO:0002211 GO:0042551 ! regulates (processual) neuron maturation [Term] id: GO:0014042 name: positive regulation of neuron maturation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of neuron maturation." [GOC:ef] synonym: "up regulation of neuron maturation" EXACT [] synonym: "up-regulation of neuron maturation" EXACT [] synonym: "upregulation of neuron maturation" EXACT [] is_a: GO:0014041 ! regulation of neuron maturation is_a: GO:1903431 ! positive regulation of cell maturation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0042551 ! positively regulates neuron maturation relationship: RO:0002213 GO:0042551 ! positively regulates neuron maturation [Term] id: GO:0014043 name: negative regulation of neuron maturation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of neuron maturation." [GOC:ef] synonym: "down regulation of neuron maturation" EXACT [] synonym: "down-regulation of neuron maturation" EXACT [] synonym: "downregulation of neuron maturation" EXACT [] is_a: GO:0014041 ! regulation of neuron maturation is_a: GO:1903430 ! negative regulation of cell maturation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0042551 ! negatively regulates neuron maturation relationship: RO:0002212 GO:0042551 ! negatively regulates neuron maturation [Term] id: GO:0014055 name: acetylcholine secretion, neurotransmission namespace: biological_process def: "The regulated release of acetylcholine by a cell. The acetylcholine acts as a neurotransmitter that acts in both the peripheral nervous system (PNS) and central nervous system (CNS)." [GOC:ef] is_a: GO:0007269 ! neurotransmitter secretion is_a: GO:0061526 ! acetylcholine secretion intersection_of: GO:0061526 ! acetylcholine secretion intersection_of: BFO:0000050 GO:0007271 ! part of synaptic transmission, cholinergic relationship: BFO:0000050 GO:0007271 ! part of synaptic transmission, cholinergic [Term] id: GO:0014056 name: regulation of acetylcholine secretion, neurotransmission namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of acetylcholine." [GOC:ef] is_a: GO:0032222 ! regulation of synaptic transmission, cholinergic is_a: GO:0046928 ! regulation of neurotransmitter secretion is_a: GO:0051952 ! regulation of amine transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0014055 ! regulates (processual) acetylcholine secretion, neurotransmission relationship: RO:0002211 GO:0014055 ! regulates (processual) acetylcholine secretion, neurotransmission [Term] id: GO:0014057 name: positive regulation of acetylcholine secretion, neurotransmission namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of acetylcholine." [GOC:ef] synonym: "up regulation of acetylcholine secretion" EXACT [] synonym: "up-regulation of acetylcholine secretion" EXACT [] synonym: "upregulation of acetylcholine secretion" EXACT [] is_a: GO:0001956 ! positive regulation of neurotransmitter secretion is_a: GO:0014056 ! regulation of acetylcholine secretion, neurotransmission is_a: GO:0032224 ! positive regulation of synaptic transmission, cholinergic is_a: GO:0051954 ! positive regulation of amine transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0014055 ! positively regulates acetylcholine secretion, neurotransmission relationship: RO:0002213 GO:0014055 ! positively regulates acetylcholine secretion, neurotransmission [Term] id: GO:0014058 name: negative regulation of acetylcholine secretion, neurotransmission namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of acetylcholine." [GOC:ef] synonym: "down regulation of acetylcholine secretion" EXACT [] synonym: "down-regulation of acetylcholine secretion" EXACT [] synonym: "downregulation of acetylcholine secretion" EXACT [] is_a: GO:0014056 ! regulation of acetylcholine secretion, neurotransmission is_a: GO:0032223 ! negative regulation of synaptic transmission, cholinergic is_a: GO:0046929 ! negative regulation of neurotransmitter secretion is_a: GO:0051953 ! negative regulation of amine transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0014055 ! negatively regulates acetylcholine secretion, neurotransmission relationship: RO:0002212 GO:0014055 ! negatively regulates acetylcholine secretion, neurotransmission [Term] id: GO:0014061 name: regulation of norepinephrine secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of norepinephrine." [GOC:ef] synonym: "regulation of noradrenaline secretion" EXACT [] is_a: GO:0050433 ! regulation of catecholamine secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048243 ! regulates (processual) norepinephrine secretion relationship: RO:0002211 GO:0048243 ! regulates (processual) norepinephrine secretion [Term] id: GO:0014062 name: regulation of serotonin secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of serotonin." [GOC:ef] is_a: GO:0043269 ! regulation of monoatomic ion transport is_a: GO:1903530 ! regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001820 ! regulates (processual) serotonin secretion relationship: RO:0002211 GO:0001820 ! regulates (processual) serotonin secretion [Term] id: GO:0014063 name: negative regulation of serotonin secretion namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of serotonin." [GOC:ef] synonym: "down regulation of serotonin secretion" EXACT [] synonym: "down-regulation of serotonin secretion" EXACT [] synonym: "downregulation of serotonin secretion" EXACT [] is_a: GO:0014062 ! regulation of serotonin secretion is_a: GO:0043271 ! negative regulation of monoatomic ion transport is_a: GO:1903531 ! negative regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001820 ! negatively regulates serotonin secretion relationship: RO:0002212 GO:0001820 ! negatively regulates serotonin secretion [Term] id: GO:0014064 name: positive regulation of serotonin secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of serotonin." [GOC:ef] synonym: "up regulation of serotonin secretion" EXACT [] synonym: "up-regulation of serotonin secretion" EXACT [] synonym: "upregulation of serotonin secretion" EXACT [] is_a: GO:0014062 ! regulation of serotonin secretion is_a: GO:0043270 ! positive regulation of monoatomic ion transport is_a: GO:1903532 ! positive regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001820 ! positively regulates serotonin secretion relationship: RO:0002213 GO:0001820 ! positively regulates serotonin secretion [Term] id: GO:0014070 name: response to organic cyclic compound namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus." [GOC:ef] synonym: "response to organic cyclic substance" EXACT [GOC:mah] is_a: GO:0010033 ! response to organic substance intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:33832 ! has primary input organic cyclic compound relationship: RO:0004009 CHEBI:33832 ! has primary input organic cyclic compound [Term] id: GO:0014075 name: response to amine namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups." [GOC:ef] synonym: "response to amine stimulus" EXACT [GOC:dos] is_a: GO:0010243 ! response to organonitrogen compound intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:32952 ! has primary input amine relationship: RO:0004009 CHEBI:32952 ! has primary input amine [Term] id: GO:0014706 name: striated muscle tissue development namespace: biological_process def: "The process whose specific outcome is the progression of a striated muscle over time, from its formation to the mature structure. Striated muscle contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. Skeletal muscle myoblasts fuse to form myotubes and eventually multinucleated muscle fibers. The fusion of cardiac cells is very rare and can only form binucleate cells." [CL:0000737, GOC:dph, GOC:mtg_muscle] is_a: GO:0060537 ! muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002036 ! results in development of striated muscle tissue relationship: RO:0002296 UBERON:0002036 ! results in development of striated muscle tissue [Term] id: GO:0014733 name: regulation of skeletal muscle adaptation namespace: biological_process def: "Any process in which skeletal muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities." [GOC:mtg_muscle] is_a: GO:0043502 ! regulation of muscle adaptation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0043501 ! regulates (processual) skeletal muscle adaptation relationship: RO:0002211 GO:0043501 ! regulates (processual) skeletal muscle adaptation [Term] id: GO:0014734 name: skeletal muscle hypertrophy namespace: biological_process def: "The enlargement or overgrowth of all or part of an organ due to an increase in size (not length) of individual muscle fibers without cell division. In the case of skeletal muscle cells this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils." [GOC:mtg_muscle] is_a: GO:0014897 ! striated muscle hypertrophy is_a: GO:0043501 ! skeletal muscle adaptation intersection_of: GO:0014896 ! muscle hypertrophy intersection_of: BFO:0000066 UBERON:0001134 ! occurs in skeletal muscle tissue [Term] id: GO:0014741 name: negative regulation of muscle hypertrophy namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hypertrophy." [GOC:mtg_muscle] is_a: GO:0014743 ! regulation of muscle hypertrophy is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0014896 ! negatively regulates muscle hypertrophy relationship: RO:0002212 GO:0014896 ! negatively regulates muscle hypertrophy [Term] id: GO:0014742 name: positive regulation of muscle hypertrophy namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of muscle hypertrophy." [GOC:mtg_muscle] is_a: GO:0014743 ! regulation of muscle hypertrophy is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0014896 ! positively regulates muscle hypertrophy relationship: RO:0002213 GO:0014896 ! positively regulates muscle hypertrophy [Term] id: GO:0014743 name: regulation of muscle hypertrophy namespace: biological_process def: "Any process that modulates the frequency, rate or extent of muscle hypertrophy." [GOC:mtg_muscle] is_a: GO:0090257 ! regulation of muscle system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0014896 ! regulates (processual) muscle hypertrophy relationship: RO:0002211 GO:0014896 ! regulates (processual) muscle hypertrophy [Term] id: GO:0014744 name: positive regulation of muscle adaptation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of muscle adaptation." [GOC:mtg_muscle] is_a: GO:0043502 ! regulation of muscle adaptation is_a: GO:0048584 ! positive regulation of response to stimulus is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0043500 ! positively regulates muscle adaptation relationship: RO:0002213 GO:0043500 ! positively regulates muscle adaptation [Term] id: GO:0014745 name: negative regulation of muscle adaptation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle adaptation." [GOC:mtg_muscle] is_a: GO:0043502 ! regulation of muscle adaptation is_a: GO:0048585 ! negative regulation of response to stimulus is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0043500 ! negatively regulates muscle adaptation relationship: RO:0002212 GO:0043500 ! negatively regulates muscle adaptation [Term] id: GO:0014805 name: smooth muscle adaptation namespace: biological_process def: "Any process in which smooth muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities." [GOC:mtg_muscle] is_a: GO:0043500 ! muscle adaptation intersection_of: GO:0043500 ! muscle adaptation intersection_of: BFO:0000066 UBERON:0001135 ! occurs in smooth muscle tissue relationship: BFO:0000066 UBERON:0001135 ! occurs in smooth muscle tissue [Term] id: GO:0014807 name: regulation of somitogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of somitogenesis." [GOC:mtg_muscle] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001756 ! regulates (processual) somitogenesis relationship: RO:0002211 GO:0001756 ! regulates (processual) somitogenesis [Term] id: GO:0014812 name: muscle cell migration namespace: biological_process def: "The orderly movement of a muscle cell from one site to another, often during the development of a multicellular organism." [CL:0000187, GOC:mtg_muscle] is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000187 ! results in movement of muscle cell relationship: RO:0002565 CL:0000187 ! results in movement of muscle cell [Term] id: GO:0014819 name: regulation of skeletal muscle contraction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of skeletal muscle contraction." [GOC:ef, GOC:mtg_muscle] is_a: GO:0006942 ! regulation of striated muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003009 ! regulates (processual) skeletal muscle contraction relationship: RO:0002211 GO:0003009 ! regulates (processual) skeletal muscle contraction [Term] id: GO:0014821 name: phasic smooth muscle contraction namespace: biological_process def: "A process in which force is generated within phasic smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the phasic smooth muscle, the muscle contraction occurs without an ordered sarcomeric structure. Phasic smooth muscle contraction occurs in a series of discrete contractions and relaxations." [GOC:mtg_muscle] is_a: GO:0006939 ! smooth muscle contraction [Term] id: GO:0014827 name: intestine smooth muscle contraction namespace: biological_process def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the intestine. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The intestine is the section of the alimentary canal from the stomach to the anal canal. It includes the large intestine and small intestine." [GOC:mtg_muscle, MA:0001539, MSH:D007422] is_a: GO:0014821 ! phasic smooth muscle contraction is_a: GO:0014831 ! gastro-intestinal system smooth muscle contraction [Term] id: GO:0014831 name: gastro-intestinal system smooth muscle contraction namespace: biological_process def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the gastro-intestinal system. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The gastro-intestinal system generally refers to the digestive structures stretching from the mouth to anus, but does not include the accessory glandular organs (liver, pancreas and biliary tract)." [GOC:mtg_muscle, MA:0001523, MSH:D041981] is_a: GO:0006939 ! smooth muscle contraction [Term] id: GO:0014832 name: urinary bladder smooth muscle contraction namespace: biological_process def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary bladder. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary bladder is a musculomembranous sac along the urinary tract." [GOC:mr, GOC:mtg_muscle, PMID:11768524, PMID:18276178, PMID:538956] is_a: GO:0014848 ! urinary tract smooth muscle contraction [Term] id: GO:0014848 name: urinary tract smooth muscle contraction namespace: biological_process def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary tract. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary tract consists of organs of the body that produce and discharge urine. These include the kidneys, ureters, bladder, and urethra." [GOC:ef, GOC:mtg_muscle, MA:0000325, MSH:D014551] is_a: GO:0006939 ! smooth muscle contraction [Term] id: GO:0014849 name: ureter smooth muscle contraction namespace: biological_process def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the ureter. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder." [GOC:mtg_muscle, MA:0000378] is_a: GO:0014821 ! phasic smooth muscle contraction is_a: GO:0014848 ! urinary tract smooth muscle contraction [Term] id: GO:0014852 name: regulation of skeletal muscle contraction by neural stimulation via neuromuscular junction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of skeletal muscle contraction by variation of the pattern of stimulation by nervous system." [GOC:ef, GOC:mtg_muscle] is_a: GO:0014819 ! regulation of skeletal muscle contraction [Term] id: GO:0014855 name: striated muscle cell proliferation namespace: biological_process def: "The multiplication or reproduction of striated muscle cells, resulting in the expansion of a cell population. Striated muscles contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle." [CL:0000737, GOC:ef, GOC:mtg_muscle] is_a: GO:0033002 ! muscle cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000737 ! acts on population of striated muscle cell relationship: RO:0012003 CL:0000737 ! acts on population of striated muscle cell [Term] id: GO:0014856 name: skeletal muscle cell proliferation namespace: biological_process def: "The multiplication or reproduction of skeletal muscle cells, resulting in the expansion of a cell population." [CL:0000188, GOC:ef, GOC:mtg_muscle] is_a: GO:0014855 ! striated muscle cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000188 ! acts on population of cell of skeletal muscle relationship: RO:0012003 CL:0000188 ! acts on population of cell of skeletal muscle [Term] id: GO:0014857 name: regulation of skeletal muscle cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of skeletal muscle cell proliferation." [CL:0000188, GOC:ef, GOC:mtg_muscle] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0014856 ! regulates (processual) skeletal muscle cell proliferation relationship: RO:0002211 GO:0014856 ! regulates (processual) skeletal muscle cell proliferation [Term] id: GO:0014858 name: positive regulation of skeletal muscle cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of skeletal muscle cell proliferation." [CL:0000188, GOC:ef, GOC:mtg_muscle] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0014857 ! regulation of skeletal muscle cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0014856 ! positively regulates skeletal muscle cell proliferation relationship: RO:0002213 GO:0014856 ! positively regulates skeletal muscle cell proliferation [Term] id: GO:0014859 name: negative regulation of skeletal muscle cell proliferation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle cell proliferation." [CL:0000188, GOC:ef, GOC:mtg_muscle] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0014857 ! regulation of skeletal muscle cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0014856 ! negatively regulates skeletal muscle cell proliferation relationship: RO:0002212 GO:0014856 ! negatively regulates skeletal muscle cell proliferation [Term] id: GO:0014860 name: neurotransmitter secretion involved in regulation of skeletal muscle contraction namespace: biological_process def: "The regulated release of neurotransmitter into the synaptic cleft involved in skeletal muscle contraction. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin." [GOC:dph, GOC:mtg_muscle, GOC:tb] synonym: "neurotransmitter secretion involved in control of skeletal muscle contraction" EXACT [GOC:dph, GOC:tb] is_a: GO:0007269 ! neurotransmitter secretion intersection_of: GO:0007269 ! neurotransmitter secretion intersection_of: BFO:0000050 GO:0014819 ! part of regulation of skeletal muscle contraction relationship: BFO:0000050 GO:0014852 ! part of regulation of skeletal muscle contraction by neural stimulation via neuromuscular junction [Term] id: GO:0014861 name: regulation of skeletal muscle contraction via regulation of action potential namespace: biological_process def: "Any process that modulates the frequency, rate or extent of skeletal muscle contraction by depolarization of muscle membrane and ionic fluxes." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:mtg_muscle] is_a: GO:0014819 ! regulation of skeletal muscle contraction is_a: GO:0098900 ! regulation of action potential intersection_of: GO:0050789 ! regulation of biological process intersection_of: RO:0002211 GO:0100001 ! regulates (processual) regulation of skeletal muscle contraction by action potential relationship: RO:0002211 GO:0100001 ! regulates (processual) regulation of skeletal muscle contraction by action potential [Term] id: GO:0014866 name: skeletal myofibril assembly namespace: biological_process def: "The process whose specific outcome is the progression of the skeletal myofibril over time, from its formation to the mature structure. A skeletal myofibril is a myofibril specific to skeletal muscle cells." [GOC:ef, GOC:mtg_muscle] is_a: GO:0030239 ! myofibril assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0098723 ! results in assembly of skeletal muscle myofibril relationship: RO:0002588 GO:0098723 ! results in assembly of skeletal muscle myofibril [Term] id: GO:0014872 name: myoblast division namespace: biological_process def: "The process resulting in the physical partitioning and separation of a myoblast into daughter cells. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:ef, GOC:mtg_muscle] is_a: GO:0051301 ! cell division intersection_of: GO:0051301 ! cell division intersection_of: RO:0004009 CL:0000056 ! has primary input myoblast relationship: RO:0004009 CL:0000056 ! has primary input myoblast [Term] id: GO:0014874 name: response to stimulus involved in regulation of muscle adaptation namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. This occurs as part of the regulation of muscle adaptation." [GOC:ef, GOC:mtg_muscle] is_a: GO:0050896 ! response to stimulus intersection_of: GO:0050896 ! response to stimulus intersection_of: BFO:0000050 GO:0043502 ! part of regulation of muscle adaptation relationship: BFO:0000050 GO:0043502 ! part of regulation of muscle adaptation [Term] id: GO:0014878 name: response to electrical stimulus involved in regulation of muscle adaptation namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus. This process occurs as part of the regulation of muscle adaptation." [GOC:ef, GOC:mtg_muscle] is_a: GO:0014874 ! response to stimulus involved in regulation of muscle adaptation is_a: GO:0051602 ! response to electrical stimulus intersection_of: GO:0051602 ! response to electrical stimulus intersection_of: BFO:0000050 GO:0043502 ! part of regulation of muscle adaptation [Term] id: GO:0014879 name: detection of electrical stimulus involved in regulation of muscle adaptation namespace: biological_process def: "The series of events by which an electrical stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation." [GOC:ef, GOC:mtg_muscle] is_a: GO:0014878 ! response to electrical stimulus involved in regulation of muscle adaptation is_a: GO:0050981 ! detection of electrical stimulus intersection_of: GO:0050981 ! detection of electrical stimulus intersection_of: BFO:0000050 GO:0043502 ! part of regulation of muscle adaptation [Term] id: GO:0014887 name: cardiac muscle adaptation namespace: biological_process def: "The process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors." [GOC:mtg_muscle] is_a: GO:0014888 ! striated muscle adaptation intersection_of: GO:0043500 ! muscle adaptation intersection_of: BFO:0000066 UBERON:0001133 ! occurs in cardiac muscle tissue relationship: BFO:0000066 UBERON:0001133 ! occurs in cardiac muscle tissue [Term] id: GO:0014888 name: striated muscle adaptation namespace: biological_process def: "Any process in which striated muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities." [GOC:mtg_muscle] is_a: GO:0043500 ! muscle adaptation intersection_of: GO:0043500 ! muscle adaptation intersection_of: BFO:0000066 UBERON:0002036 ! occurs in striated muscle tissue relationship: BFO:0000066 UBERON:0002036 ! occurs in striated muscle tissue [Term] id: GO:0014895 name: smooth muscle hypertrophy namespace: biological_process def: "The enlargement or overgrowth of all or part of an organ due to an increase in size of its smooth muscle cells without cell division. Physiological hypertrophy is a normal process during development, and can also occur in mature structures on demand. In the uterus, smooth muscle cells undergo hypertrophy during pregnancy." [GOC:mtg_muscle] is_a: GO:0014805 ! smooth muscle adaptation is_a: GO:0014896 ! muscle hypertrophy intersection_of: GO:0014896 ! muscle hypertrophy intersection_of: BFO:0000066 UBERON:0001135 ! occurs in smooth muscle tissue [Term] id: GO:0014896 name: muscle hypertrophy namespace: biological_process def: "The muscle system process that results in enlargement or overgrowth of all or part of a muscle organ due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development (it stops in cardiac muscle after adolescence) and can also be brought on in response to demand. In athletes cardiac and skeletal muscles undergo hypertrophy stimulated by increasing muscle activity on exercise. Smooth muscle cells in the uterus undergo hypertrophy during pregnancy." [GOC:mtg_muscle] xref: Wikipedia:Muscle_hypertrophy is_a: GO:0003012 ! muscle system process relationship: BFO:0000066 UBERON:0002385 ! occurs in muscle tissue [Term] id: GO:0014897 name: striated muscle hypertrophy namespace: biological_process def: "The enlargement or overgrowth of all or part of an organ due to an increase in size of muscle cells without cell division. In the case of striated muscle, this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils." [GOC:mtg_muscle] is_a: GO:0014896 ! muscle hypertrophy intersection_of: GO:0014896 ! muscle hypertrophy intersection_of: RO:0004009 UBERON:0002036 ! has primary input striated muscle tissue relationship: RO:0004009 UBERON:0002036 ! has primary input striated muscle tissue [Term] id: GO:0014902 name: myotube differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." [GOC:mtg_muscle] is_a: GO:0051146 ! striated muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0002372 ! results in acquisition of features of myotube relationship: RO:0002315 CL:0002372 ! results in acquisition of features of myotube [Term] id: GO:0014904 name: myotube cell development namespace: biological_process def: "The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." [GOC:mtg_muscle] is_a: GO:0055002 ! striated muscle cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0002372 ! results in development of myotube relationship: BFO:0000050 GO:0014902 ! part of myotube differentiation relationship: RO:0002296 CL:0002372 ! results in development of myotube [Term] id: GO:0014909 name: smooth muscle cell migration namespace: biological_process def: "The orderly movement of a smooth muscle cell from one site to another, often during the development of a multicellular organism." [CL:0000192, GOC:mtg_muscle] is_a: GO:0014812 ! muscle cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000192 ! results in movement of smooth muscle cell relationship: RO:0002565 CL:0000192 ! results in movement of smooth muscle cell [Term] id: GO:0014910 name: regulation of smooth muscle cell migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of smooth muscle cell migration." [CL:0000192, GOC:mtg_muscle] is_a: GO:0030334 ! regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0014909 ! regulates (processual) smooth muscle cell migration relationship: RO:0002211 GO:0014909 ! regulates (processual) smooth muscle cell migration [Term] id: GO:0014911 name: positive regulation of smooth muscle cell migration namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of smooth muscle cell migration." [CL:0000192, GOC:mtg_muscle] is_a: GO:0014910 ! regulation of smooth muscle cell migration is_a: GO:0030335 ! positive regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0014909 ! positively regulates smooth muscle cell migration relationship: RO:0002213 GO:0014909 ! positively regulates smooth muscle cell migration [Term] id: GO:0014912 name: negative regulation of smooth muscle cell migration namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell migration." [CL:0000192, GOC:mtg_muscle] is_a: GO:0014910 ! regulation of smooth muscle cell migration is_a: GO:0030336 ! negative regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0014909 ! negatively regulates smooth muscle cell migration relationship: RO:0002212 GO:0014909 ! negatively regulates smooth muscle cell migration [Term] id: GO:0015031 name: protein transport namespace: biological_process def: "The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] is_a: GO:0008104 ! protein localization is_a: GO:0045184 ! establishment of protein localization is_a: GO:0071702 ! organic substance transport is_a: GO:0071705 ! nitrogen compound transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 PR:000000001 ! has primary input protein [Term] id: GO:0015075 name: monoatomic ion transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of an ion from one side of a membrane to the other." [GOC:dgf, GOC:mtg_transport, ISBN:0815340729] synonym: "ion transporter activity" EXACT [] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:24867 ! has primary input monoatomic ion relationship: BFO:0000050 GO:0034220 ! part of monoatomic ion transmembrane transport relationship: RO:0004009 CHEBI:24867 ! has primary input monoatomic ion [Term] id: GO:0015081 name: sodium ion transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of sodium ions (Na+) from one side of a membrane to the other." [GOC:ai, GOC:BHF, RHEA:34963] synonym: "sodium transporter activity" EXACT [] xref: RHEA:34963 is_a: GO:0046873 ! metal ion transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:29101 ! has primary input sodium(1+) relationship: BFO:0000050 GO:0035725 ! part of sodium ion transmembrane transport relationship: RO:0004009 CHEBI:29101 ! has primary input sodium(1+) [Term] id: GO:0015101 name: organic cation transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of organic cations from one side of a membrane to the other. Organic cations are atoms or small molecules with a positive charge that contain carbon in covalent linkage." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] xref: Reactome:R-HSA-2161500 "abacavir [extracellular] => abacavir [cytosol]" xref: Reactome:R-HSA-549129 "OCT1 transports organic cations into hepatic cells" xref: Reactome:R-HSA-549279 "OCT2 mediates tubular uptake of organic cations in the kidney" xref: Reactome:R-HSA-549304 "OCT3 mediates renal clearance of organic cations" xref: Reactome:R-HSA-549322 "OCT1 transports organic cations out of hepatic cells" xref: Reactome:R-HSA-561054 "OCT2 mediates tubular secretion of organic cations in the kidney" xref: Reactome:R-HSA-561072 "OCT3 mediates renal uptake of organic cations" xref: Reactome:R-HSA-9794270 "SLCO1A2 transports Cipro(1+) into the cytosol" xref: Reactome:R-HSA-9794523 "SLC22A1 transports Cipro into renal cell" xref: Reactome:R-HSA-9795207 "SLC22A1 transports Cipro into hepatic cell" is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:25697 ! has primary input organic cation relationship: BFO:0000050 GO:0015695 ! part of organic cation transport relationship: RO:0004009 CHEBI:25697 ! has primary input organic cation [Term] id: GO:0015103 name: inorganic anion transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of inorganic anions from one side of a membrane to the other. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage." [GOC:ai] is_a: GO:0015318 ! inorganic molecular entity transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:24834 ! has primary input inorganic anion relationship: BFO:0000050 GO:0015698 ! part of inorganic anion transport relationship: RO:0004009 CHEBI:24834 ! has primary input inorganic anion [Term] id: GO:0015106 name: bicarbonate transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of bicarbonate from one side of a membrane to the other. Bicarbonate is the hydrogencarbonate ion, HCO3-." [GOC:ai] xref: Reactome:R-HSA-2752067 "BESTs transport cytosolic HCO3- to extracellular region" xref: RHEA:28695 is_a: GO:0008514 ! organic anion transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:17544 ! has primary input hydrogencarbonate relationship: BFO:0000050 GO:0015701 ! part of bicarbonate transport relationship: RO:0004009 CHEBI:17544 ! has primary input hydrogencarbonate [Term] id: GO:0015114 name: phosphate ion transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of phosphate (PO4 3-) ions from one side of a membrane to the other." [GOC:ai] xref: RHEA:32823 is_a: GO:0015103 ! inorganic anion transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:35780 ! has primary input phosphate ion relationship: BFO:0000050 GO:0035435 ! part of phosphate ion transmembrane transport relationship: RO:0000057 CHEBI:43474 ! has participant hydrogenphosphate relationship: RO:0004009 CHEBI:35780 ! has primary input phosphate ion creation_date: 2012-11-22T15:43:10Z [Term] id: GO:0015116 name: sulfate transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of sulfate ions, SO4(2-), from one side of a membrane to the other." [GOC:ai] synonym: "sulphate transporter activity" EXACT [] xref: Reactome:R-HSA-3560789 "Defective SLC26A2 does not cotransport extracellular SO4(2-), H+ to cytosol" xref: Reactome:R-HSA-427555 "SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol" xref: Reactome:R-HSA-8875871 "SLC26A11 transports SO4(2-) from extracellular region to cytosol" xref: RHEA:34983 is_a: GO:0015103 ! inorganic anion transmembrane transporter activity is_a: GO:1901682 ! sulfur compound transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:16189 ! has primary input sulfate relationship: BFO:0000050 GO:1902358 ! part of sulfate transmembrane transport relationship: RO:0004009 CHEBI:16189 ! has primary input sulfate [Term] id: GO:0015123 name: acetate transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of acetate from one side of a membrane to the other. Acetate is the 2-carbon carboxylic acid ethanoic acid." [GOC:ai] is_a: GO:0046943 ! carboxylic acid transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:30089 ! has primary input acetate relationship: BFO:0000050 GO:0035433 ! part of acetate transmembrane transport relationship: RO:0004009 CHEBI:30089 ! has primary input acetate [Term] id: GO:0015125 name: bile acid transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of bile acid from one side of a membrane to the other. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine." [GOC:ai] xref: Reactome:R-HSA-194079 "SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol" xref: Reactome:R-HSA-194083 "SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol" xref: Reactome:R-HSA-194130 "Transport (influx) of bile salts and acids by OATP-A" xref: Reactome:R-HSA-5661184 "Defective SLCO1B1 does not transport BIL from extracellular region (blood) to cytosol (hepatocyte)" xref: Reactome:R-HSA-5661198 "Defective SLCO1B3 does not transport BIL from extracellular region (blood) to cytosol (hepatocyte)" xref: Reactome:R-HSA-9733964 "SLC51A:SLC51B transports bile salts from cytosol to extracellular region" is_a: GO:0005319 ! lipid transporter activity is_a: GO:0008028 ! monocarboxylic acid transmembrane transporter activity is_a: GO:1901618 ! organic hydroxy compound transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:3098 ! has primary input bile acid relationship: BFO:0000050 GO:0015721 ! part of bile acid and bile salt transport relationship: RO:0004009 CHEBI:3098 ! has primary input bile acid [Term] id: GO:0015127 name: bilirubin transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of bilirubin from one side of a membrane to the other. Bilirubin is a linear tetrapyrrole produced in the reticuloendothelial system from biliverdin and transported to the liver as a complex with serum albumin. In the liver, bilirubin is converted to bilirubin bisglucuronide, which is excreted in the bile." [GOC:ai, ISBN:0198547684] xref: Reactome:R-HSA-5679031 "Defective ABCC2 does not transport BMG,BDG from cytosol to extracellular region" xref: Reactome:R-HSA-5679041 "ABCC2 transports BMG,BDG from cytosol to extracellular region" xref: Reactome:R-HSA-9661417 "ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region" is_a: GO:0046943 ! carboxylic acid transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:57977 ! has primary input bilirubin(2-) relationship: BFO:0000050 GO:0015723 ! part of bilirubin transport relationship: RO:0004009 CHEBI:57977 ! has primary input bilirubin(2-) [Term] id: GO:0015144 name: carbohydrate transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of carbohydrate from one side of a membrane to the other." [GOC:jl, GOC:mtg_transport, ISBN:0815340729] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:16646 ! has primary input carbohydrate relationship: BFO:0000050 GO:0034219 ! part of carbohydrate transmembrane transport relationship: RO:0004009 CHEBI:16646 ! has primary input carbohydrate [Term] id: GO:0015145 name: monosaccharide transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of a monosaccharide from one side of a membrane to the other." [GOC:jl, GOC:mtg_transport, ISBN:0815340729] is_a: GO:0051119 ! sugar transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:35381 ! has primary input monosaccharide relationship: BFO:0000050 GO:0015749 ! part of monosaccharide transmembrane transport relationship: RO:0004009 CHEBI:35381 ! has primary input monosaccharide [Term] id: GO:0015149 name: hexose transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of a hexose sugar, a monosaccharide with 6 carbon atoms, from one side of a membrane to the other." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] xref: Reactome:R-HSA-189242 "SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region" xref: Reactome:R-HSA-5638222 "Defective SLC2A2 does not transport Fru, Gal, Glc from cytosol to extracellular region" is_a: GO:0015145 ! monosaccharide transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:18133 ! has primary input hexose relationship: BFO:0000050 GO:0008645 ! part of hexose transmembrane transport relationship: RO:0004009 CHEBI:18133 ! has primary input hexose [Term] id: GO:0015159 name: polysaccharide transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of polysaccharides from one side of a membrane to the other. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] is_a: GO:0015144 ! carbohydrate transmembrane transporter activity is_a: GO:0022884 ! macromolecule transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:18154 ! has primary input polysaccharide relationship: BFO:0000050 GO:0015774 ! part of polysaccharide transport relationship: RO:0004009 CHEBI:18154 ! has primary input polysaccharide [Term] id: GO:0015171 name: amino acid transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of amino acids from one side of a membrane to the other. Amino acids are organic molecules that contain an amino group and a carboxyl group." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] synonym: "amino acid permease activity" EXACT [] xref: Reactome:R-HSA-210439 "glutamate uptake by astrocytes" xref: Reactome:R-HSA-212642 "L-Glutamine transport into neurons" xref: Reactome:R-HSA-351963 "SLC6A18 transports Gly from extracellular region to cytosol" xref: Reactome:R-HSA-351987 "SLC6A6-mediated uptake of taurine and beta-alanine" xref: Reactome:R-HSA-352029 "SLC6A12 (BGT-1)-mediated uptake of GABA and betaine" xref: Reactome:R-HSA-352052 "SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol" xref: Reactome:R-HSA-352059 "SLC6A15-mediated amino acid uptake" xref: Reactome:R-HSA-352103 "SLC43A1 (LAT3)-mediated uptake of large neutral amino acids" xref: Reactome:R-HSA-352107 "SLC43A2 (LAT4)-mediated uptake of large neutral amino acids" xref: Reactome:R-HSA-352108 "SLC38A2 (ATA2)-mediated uptake of neutral amino acids" xref: Reactome:R-HSA-352119 "SLC38A1 (ATA1)-mediated uptake of neutral amino acids" xref: Reactome:R-HSA-352136 "SLC38A4 (ATA3)-mediated uptake of arginine and lysine" xref: Reactome:R-HSA-352158 "SLC16A10-mediated uptake of aromatic amino acids" xref: Reactome:R-HSA-352174 "SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine" xref: Reactome:R-HSA-352182 "SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine" xref: Reactome:R-HSA-352191 "SLC7A8-mediated uptake of neutral amino acids" xref: Reactome:R-HSA-352232 "SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol" xref: Reactome:R-HSA-352347 "SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine" xref: Reactome:R-HSA-352354 "SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine" xref: Reactome:R-HSA-352364 "SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine" xref: Reactome:R-HSA-352371 "SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine" xref: Reactome:R-HSA-352379 "SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane" xref: Reactome:R-HSA-352385 "SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane" xref: Reactome:R-HSA-375405 "SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol" xref: Reactome:R-HSA-375417 "SLC36A1-mediated uptake of glycine, proline, and alanine" xref: Reactome:R-HSA-375473 "SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol" xref: Reactome:R-HSA-375487 "SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol" xref: Reactome:R-HSA-375768 "SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids" xref: Reactome:R-HSA-375770 "SLC7A3 (CAT-3)-mediated uptake of cationic amino acids" xref: Reactome:R-HSA-375776 "SLC7A1 (CAT-1)-mediated uptake of cationic amino acids" xref: Reactome:R-HSA-375790 "SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids" xref: Reactome:R-HSA-376200 "SLC7A10-mediated uptake of small neutral amino acids" xref: Reactome:R-HSA-378513 "SLC7A11-mediated exchange of extracellular cysteine and cytosolic glutamate" xref: Reactome:R-HSA-379415 "SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane" xref: Reactome:R-HSA-379426 "SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine" xref: Reactome:R-HSA-379432 "SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu" xref: Reactome:R-HSA-5653850 "Defective SLC36A2 does not cotransport Gly, L-Pro with H+ from extracellular region to cytosol" xref: Reactome:R-HSA-5655702 "Defective SLC3A1 (in SLC7A9:SLC3A1) does not exchange L-Arg, CySS-, L-Lys for L-Leu" xref: Reactome:R-HSA-5659674 "Variant SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol" xref: Reactome:R-HSA-5659734 "Defective SLC6A19 does not cotransport neutral amino acids, Na+ from extracellular region to cytosol" xref: Reactome:R-HSA-5659755 "Defective SLC6A18 does not transport Gly from extracellular region to cytosol" xref: Reactome:R-HSA-5660694 "Variant SLC6A20 does not cotransport L-Pro, Na+ from extracellulare region to cytosol" xref: Reactome:R-HSA-5660890 "Defective SLC7A9 (in SLC7A9:SLC3A1) does not exchange L-Arg, CySS-, L-Lys for L-Leu" xref: Reactome:R-HSA-5660910 "Defective SLC7A7 does not exchange L-Arg for L-Leu, Na+ across the plasma membrane" xref: Reactome:R-HSA-888592 "Loading of GABA into clathrin sculpted GABA transport vesicle lumen" xref: Reactome:R-HSA-8952726 "SLC38A9 transports L-Arg from lysosomal lumen to cytosol" is_a: GO:0005342 ! organic acid transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:33709 ! has primary input amino acid relationship: BFO:0000050 GO:0003333 ! part of amino acid transmembrane transport relationship: RO:0004009 CHEBI:33709 ! has primary input amino acid [Term] id: GO:0015205 name: nucleobase transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acidfrom one side of a membrane to the other." [ISBN:0198506732] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:18282 ! has primary input nucleobase relationship: BFO:0000050 GO:0015851 ! part of nucleobase transport relationship: RO:0004009 CHEBI:18282 ! has primary input nucleobase [Term] id: GO:0015318 name: inorganic molecular entity transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of an inorganic molecular entity from the outside of a cell to the inside of the cell across a membrane. An inorganic molecular entity is a molecular entity that contains no carbon." [GOC:mtg_transport, ISBN:0815340729] synonym: "inorganic solute uptake transmembrane transporter activity" EXACT [] synonym: "inorganic uptake permease activity" EXACT [] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:24835 ! has primary input inorganic molecular entity relationship: RO:0004009 CHEBI:24835 ! has primary input inorganic molecular entity [Term] id: GO:0015629 name: actin cytoskeleton namespace: cellular_component def: "The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes." [GOC:jl, ISBN:0395825172, ISBN:0815316194] is_a: GO:0005856 ! cytoskeleton [Term] id: GO:0015630 name: microtubule cytoskeleton namespace: cellular_component def: "The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins." [GOC:jl, ISBN:0395825172] is_a: GO:0005856 ! cytoskeleton [Term] id: GO:0015669 name: gas transport namespace: biological_process def: "The directed movement of substances that are gaseous in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] is_a: GO:0006810 ! transport [Term] id: GO:0015671 name: oxygen transport namespace: biological_process def: "The directed movement of oxygen (O2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] is_a: GO:0015669 ! gas transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:15379 ! has primary input dioxygen relationship: RO:0004009 CHEBI:15379 ! has primary input dioxygen [Term] id: GO:0015695 name: organic cation transport namespace: biological_process def: "The directed movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic cations are atoms or small molecules with a positive charge which contain carbon in covalent linkage." [GOC:ai] is_a: GO:0071702 ! organic substance transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:25697 ! has primary input organic cation relationship: RO:0004009 CHEBI:25697 ! has primary input organic cation [Term] id: GO:0015698 name: inorganic anion transport namespace: biological_process def: "The directed movement of inorganic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage." [GOC:krc] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:24834 ! has primary input inorganic anion relationship: RO:0004009 CHEBI:24834 ! has primary input inorganic anion [Term] id: GO:0015701 name: bicarbonate transport namespace: biological_process def: "The directed movement of bicarbonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] is_a: GO:0015711 ! organic anion transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:17544 ! has primary input hydrogencarbonate relationship: RO:0004009 CHEBI:17544 ! has primary input hydrogencarbonate [Term] id: GO:0015711 name: organic anion transport namespace: biological_process def: "The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage." [GOC:ai, GOC:krc] is_a: GO:0071702 ! organic substance transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:25696 ! has primary input organic anion relationship: RO:0004009 CHEBI:25696 ! has primary input organic anion [Term] id: GO:0015718 name: monocarboxylic acid transport namespace: biological_process def: "The directed movement of monocarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] is_a: GO:0046942 ! carboxylic acid transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:35757 ! has primary input monocarboxylic acid anion relationship: RO:0004009 CHEBI:35757 ! has primary input monocarboxylic acid anion [Term] id: GO:0015721 name: bile acid and bile salt transport namespace: biological_process def: "The directed movement of bile acid and bile salts into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:krc, PMID:12663868, PMID:14699511] is_a: GO:0006869 ! lipid transport is_a: GO:0015718 ! monocarboxylic acid transport is_a: GO:0015849 ! organic acid transport is_a: GO:0015850 ! organic hydroxy compound transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:3098 ! has primary input bile acid relationship: RO:0004009 CHEBI:3098 ! has primary input bile acid [Term] id: GO:0015723 name: bilirubin transport namespace: biological_process def: "The directed movement of bilirubin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] is_a: GO:0006835 ! dicarboxylic acid transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:57977 ! has primary input bilirubin(2-) relationship: RO:0004009 CHEBI:57977 ! has primary input bilirubin(2-) [Term] id: GO:0015749 name: monosaccharide transmembrane transport namespace: biological_process def: "The process in which a monosaccharide is transported across a lipid bilayer, from one side of a membrane to the other. Monosaccharides are the simplest carbohydrates; they are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides." [GO_REF:0000069, GOC:TermGenie, GOC:vw] is_a: GO:0034219 ! carbohydrate transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002342 GO:0016020 ! results in transport across membrane intersection_of: RO:0004009 CHEBI:35381 ! has primary input monosaccharide relationship: RO:0004009 CHEBI:35381 ! has primary input monosaccharide creation_date: 2017-02-19T10:41:27Z [Term] id: GO:0015774 name: polysaccharide transport namespace: biological_process def: "The directed movement of polysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." [GOC:ai] is_a: GO:0008643 ! carbohydrate transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:18154 ! has primary input polysaccharide relationship: BFO:0000050 GO:0033037 ! part of polysaccharide localization relationship: RO:0004009 CHEBI:18154 ! has primary input polysaccharide [Term] id: GO:0015833 name: peptide transport namespace: biological_process def: "The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] is_a: GO:0042886 ! amide transport is_a: GO:0071702 ! organic substance transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:16670 ! has primary input peptide relationship: RO:0004009 CHEBI:16670 ! has primary input peptide [Term] id: GO:0015837 name: amine transport namespace: biological_process def: "The directed movement of amines, including polyamines, organic compounds containing one or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai, ISBN:0198506732] is_a: GO:0071702 ! organic substance transport is_a: GO:0071705 ! nitrogen compound transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:32952 ! has primary input amine relationship: RO:0004009 CHEBI:32952 ! has primary input amine [Term] id: GO:0015844 name: monoamine transport namespace: biological_process def: "The directed movement of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] is_a: GO:0071702 ! organic substance transport is_a: GO:0071705 ! nitrogen compound transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:63534 ! has primary input monoamine relationship: RO:0004009 CHEBI:63534 ! has primary input monoamine [Term] id: GO:0015849 name: organic acid transport namespace: biological_process def: "The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [ISBN:0198506732] is_a: GO:0071702 ! organic substance transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:64709 ! has primary input organic acid relationship: RO:0004009 CHEBI:64709 ! has primary input organic acid [Term] id: GO:0015850 name: organic hydroxy compound transport namespace: biological_process def: "The directed movement of an organic hydroxy compound (organic alcohol) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. An organic hydroxy compound is an organic compound having at least one hydroxy group attached to a carbon atom." [GOC:ai] synonym: "organic alcohol transport" EXACT [] is_a: GO:0071702 ! organic substance transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:33822 ! has primary input organic hydroxy compound relationship: RO:0004009 CHEBI:33822 ! has primary input organic hydroxy compound [Term] id: GO:0015851 name: nucleobase transport namespace: biological_process def: "The directed movement of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [ISBN:0198506732] synonym: "nucleobase transmembrane transport" EXACT [GOC:mah] is_a: GO:0071702 ! organic substance transport is_a: GO:0071705 ! nitrogen compound transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:18282 ! has primary input nucleobase relationship: RO:0004009 CHEBI:18282 ! has primary input nucleobase [Term] id: GO:0015869 name: protein-DNA complex transport namespace: biological_process def: "The directed movement of protein-DNA complexes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "DNA-protein complex transport" EXACT [GOC:mah] is_a: GO:0006886 ! intracellular protein transport is_a: GO:0015931 ! nucleobase-containing compound transport is_a: GO:0031503 ! protein-containing complex localization intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 GO:0032993 ! has primary input protein-DNA complex relationship: RO:0004009 GO:0032993 ! has primary input protein-DNA complex [Term] id: GO:0015870 name: acetylcholine transport namespace: biological_process def: "The directed movement of acetylcholine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions." [GOC:ai] is_a: GO:0015695 ! organic cation transport is_a: GO:0071705 ! nitrogen compound transport is_a: GO:1901374 ! acetate ester transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:15355 ! has primary input acetylcholine relationship: RO:0004009 CHEBI:15355 ! has primary input acetylcholine [Term] id: GO:0015874 name: norepinephrine transport namespace: biological_process def: "The directed movement of norepinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine." [GOC:ai, ISBN:0198506732] synonym: "levarterenol transport" EXACT [] synonym: "noradrenaline transport" EXACT [] is_a: GO:0015695 ! organic cation transport is_a: GO:0051937 ! catecholamine transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:72587 ! has primary input (R)-noradrenaline(1+) relationship: RO:0004009 CHEBI:72587 ! has primary input (R)-noradrenaline(1+) [Term] id: GO:0015931 name: nucleobase-containing compound transport namespace: biological_process def: "The directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] is_a: GO:0071702 ! organic substance transport is_a: GO:0071705 ! nitrogen compound transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:61120 ! has primary input nucleobase-containing molecular entity relationship: RO:0004009 CHEBI:61120 ! has primary input nucleobase-containing molecular entity [Term] id: GO:0015932 name: nucleobase-containing compound transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of nucleobases, nucleosides, nucleotides and nucleic acids from one side of a membrane to the other." [GOC:ai] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:61120 ! has primary input nucleobase-containing molecular entity relationship: BFO:0000050 GO:0015931 ! part of nucleobase-containing compound transport relationship: RO:0004009 CHEBI:61120 ! has primary input nucleobase-containing molecular entity [Term] id: GO:0015980 name: energy derivation by oxidation of organic compounds namespace: biological_process def: "The chemical reactions and pathways by which a cell derives energy from organic compounds; results in the oxidation of the compounds from which energy is released." [GOC:mah] synonym: "chemoorganotrophy" EXACT [] is_a: GO:0006091 ! generation of precursor metabolites and energy [Term] id: GO:0016020 name: membrane namespace: cellular_component def: "A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it." [GOC:dos, GOC:mah, ISBN:0815316194] xref: Wikipedia:Biological_membrane xref: Wikipedia:Transmembrane_protein is_a: GO:0110165 ! cellular anatomical entity disjoint_from: GO:0031012 ! extracellular matrix creation_date: 2014-03-06T11:37:54Z [Term] id: GO:0016042 name: lipid catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent." [GOC:go_curators] synonym: "lipid breakdown" EXACT [] synonym: "lipid catabolism" EXACT [] synonym: "lipid degradation" EXACT [] synonym: "lipolysis" EXACT [] xref: Wikipedia:Lipid_catabolism is_a: GO:0006629 ! lipid metabolic process is_a: GO:1901575 ! organic substance catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:18059 ! has primary input lipid relationship: RO:0004009 CHEBI:18059 ! has primary input lipid [Term] id: GO:0016043 name: cellular component organization namespace: biological_process def: "A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component." [GOC:ai, GOC:jl, GOC:mah] synonym: "cell organisation" EXACT [] synonym: "cellular component organisation at cellular level" EXACT [GOC:mah] synonym: "cellular component organisation in other organism" EXACT [GOC:mah] synonym: "cellular component organization at cellular level" EXACT [] synonym: "cellular component organization in other organism" EXACT [] is_a: GO:0071840 ! cellular component organization or biogenesis intersection_of: GO:0009987 ! cellular process intersection_of: RO:0002592 GO:0005575 ! results in organization of cellular_component relationship: RO:0002592 GO:0005575 ! results in organization of cellular_component [Term] id: GO:0016049 name: cell growth namespace: biological_process def: "The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present." [GOC:ai] synonym: "cellular growth" EXACT [] synonym: "growth of cell" EXACT [] is_a: GO:0009987 ! cellular process is_a: GO:0040007 ! growth intersection_of: GO:0040007 ! growth intersection_of: RO:0002343 CL:0000000 ! results in growth of cell relationship: RO:0002343 CL:0000000 ! results in growth of cell [Term] id: GO:0016050 name: vesicle organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle." [GOC:mah] synonym: "vesicle organisation" EXACT [] is_a: GO:0006996 ! organelle organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0031982 ! results in organization of vesicle relationship: RO:0002592 GO:0031982 ! results in organization of vesicle [Term] id: GO:0016051 name: carbohydrate biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y." [ISBN:0198506732] synonym: "anabolic carbohydrate metabolic process" EXACT [] synonym: "anabolic carbohydrate metabolism" EXACT [] synonym: "carbohydrate anabolism" EXACT [] synonym: "carbohydrate biosynthesis" EXACT [] synonym: "carbohydrate formation" EXACT [] synonym: "carbohydrate synthesis" EXACT [] is_a: GO:0005975 ! carbohydrate metabolic process is_a: GO:1901576 ! organic substance biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:16646 ! has primary output carbohydrate relationship: RO:0004008 CHEBI:16646 ! has primary output carbohydrate [Term] id: GO:0016052 name: carbohydrate catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y." [ISBN:0198506732] synonym: "carbohydrate breakdown" EXACT [] synonym: "carbohydrate catabolism" EXACT [] synonym: "carbohydrate degradation" EXACT [] synonym: "catabolic carbohydrate metabolic process" EXACT [] synonym: "catabolic carbohydrate metabolism" EXACT [] is_a: GO:0005975 ! carbohydrate metabolic process is_a: GO:1901575 ! organic substance catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:16646 ! has primary input carbohydrate relationship: RO:0004009 CHEBI:16646 ! has primary input carbohydrate creation_date: 2012-10-23T16:34:39Z [Term] id: GO:0016053 name: organic acid biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of organic acids, any acidic compound containing carbon in covalent linkage." [ISBN:0198506732] synonym: "organic acid anabolism" EXACT [] synonym: "organic acid biosynthesis" EXACT [] synonym: "organic acid formation" EXACT [] synonym: "organic acid synthesis" EXACT [] is_a: GO:0006082 ! organic acid metabolic process is_a: GO:0044249 ! cellular biosynthetic process is_a: GO:0044283 ! small molecule biosynthetic process is_a: GO:1901576 ! organic substance biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:64709 ! has primary output organic acid relationship: RO:0004008 CHEBI:64709 ! has primary output organic acid [Term] id: GO:0016054 name: organic acid catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage." [ISBN:0198506732] synonym: "organic acid breakdown" EXACT [] synonym: "organic acid catabolism" EXACT [] synonym: "organic acid degradation" EXACT [] is_a: GO:0006082 ! organic acid metabolic process is_a: GO:0044248 ! cellular catabolic process is_a: GO:0044282 ! small molecule catabolic process is_a: GO:1901575 ! organic substance catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:64709 ! has primary input organic acid relationship: RO:0004009 CHEBI:64709 ! has primary input organic acid [Term] id: GO:0016057 name: regulation of membrane potential in photoreceptor cell namespace: biological_process def: "Hyperpolarization (vertebrates) or depolarization (invertebrates) of the photoreceptor cell membrane via closing/opening of cation specific channels as a result of signals generated by rhodopsin activation by a photon." [GOC:dph, GOC:hb, GOC:tb] synonym: "changes in polarization state of photoreceptor cell membrane" EXACT [GOC:dph, GOC:tb] is_a: GO:0042391 ! regulation of membrane potential intersection_of: GO:0042391 ! regulation of membrane potential intersection_of: BFO:0000066 CL:0000210 ! occurs in photoreceptor cell relationship: BFO:0000066 CL:0000210 ! occurs in photoreceptor cell [Term] id: GO:0016070 name: RNA metabolic process namespace: biological_process def: "The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage." [ISBN:0198506732] synonym: "RNA metabolism" EXACT [] is_a: GO:0090304 ! nucleic acid metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:33697 ! has primary input or output ribonucleic acid relationship: RO:0004007 CHEBI:33697 ! has primary input or output ribonucleic acid [Term] id: GO:0016192 name: vesicle-mediated transport namespace: biological_process def: "A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane." [GOC:ai, GOC:mah, ISBN:08789310662000] synonym: "vesicle transport" EXACT [] synonym: "vesicular transport" EXACT [GOC:mah] is_a: GO:0006810 ! transport is_a: GO:0009987 ! cellular process intersection_of: GO:0006810 ! transport intersection_of: RO:0002608 GO:0031982 ! process has causal agent vesicle relationship: RO:0002608 GO:0031982 ! process has causal agent vesicle [Term] id: GO:0016202 name: regulation of striated muscle tissue development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of striated muscle development." [GOC:go_curators] is_a: GO:0048634 ! regulation of muscle organ development is_a: GO:1901861 ! regulation of muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0014706 ! regulates (processual) striated muscle tissue development relationship: RO:0002211 GO:0014706 ! regulates (processual) striated muscle tissue development [Term] id: GO:0016301 name: kinase activity namespace: molecular_function def: "Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." [ISBN:0198506732] synonym: "phosphokinase activity" EXACT [] xref: Reactome:R-HSA-6788855 "FN3KRP phosphorylates PsiAm, RibAm" xref: Reactome:R-HSA-6788867 "FN3K phosphorylates ketosamines" is_a: GO:0016772 ! transferase activity, transferring phosphorus-containing groups [Term] id: GO:0016310 name: phosphorylation namespace: biological_process def: "The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide." [ISBN:0198506732] xref: Wikipedia:Phosphorylation is_a: GO:0006796 ! phosphate-containing compound metabolic process [Term] id: GO:0016321 name: female meiosis chromosome segregation namespace: biological_process def: "The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a female." [GOC:ai] is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0045132 ! meiotic chromosome segregation intersection_of: GO:0098813 ! nuclear chromosome segregation intersection_of: BFO:0000050 GO:0007143 ! part of female meiotic nuclear division relationship: BFO:0000050 GO:0007143 ! part of female meiotic nuclear division [Term] id: GO:0016325 name: oocyte microtubule cytoskeleton organization namespace: biological_process def: "Formation and maintenance of a polarized microtubule array originating from a microtubule-organizing center (MTOC) in the oocyte. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, PMID:11231123] synonym: "oocyte microtubule cytoskeleton organisation" EXACT [] is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0030951 ! establishment or maintenance of microtubule cytoskeleton polarity intersection_of: GO:0016043 ! cellular component organization intersection_of: BFO:0000066 CL:0000023 ! occurs in oocyte intersection_of: RO:0002592 GO:0015630 ! results in organization of microtubule cytoskeleton relationship: BFO:0000050 GO:0007308 ! part of oocyte construction relationship: BFO:0000066 CL:0000023 ! occurs in oocyte [Term] id: GO:0016331 name: morphogenesis of embryonic epithelium namespace: biological_process def: "The process in which the anatomical structures of embryonic epithelia are generated and organized." [GOC:jl] is_a: GO:0002009 ! morphogenesis of an epithelium is_a: GO:0048598 ! embryonic morphogenesis [Term] id: GO:0016477 name: cell migration namespace: biological_process def: "The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues." [GOC:cjm, GOC:dph, GOC:ems, GOC:pf, Wikipedia:Cell_migration] xref: Wikipedia:Cell_migration is_a: GO:0048870 ! cell motility [Term] id: GO:0016525 name: negative regulation of angiogenesis namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis." [GOC:go_curators] synonym: "down regulation of angiogenesis" EXACT [] synonym: "down-regulation of angiogenesis" EXACT [] synonym: "downregulation of angiogenesis" EXACT [] is_a: GO:0045765 ! regulation of angiogenesis is_a: GO:2000181 ! negative regulation of blood vessel morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001525 ! negatively regulates angiogenesis relationship: RO:0002212 GO:0001525 ! negatively regulates angiogenesis [Term] id: GO:0016528 name: sarcoplasm namespace: cellular_component def: "The cytoplasm of a muscle cell; includes the sarcoplasmic reticulum." [ISBN:0198547684] xref: Wikipedia:Sarcoplasm is_a: GO:0005737 ! cytoplasm is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: GO:0005737 ! cytoplasm intersection_of: BFO:0000050 CL:0000187 ! part of muscle cell relationship: BFO:0000050 CL:0000187 ! part of muscle cell [Term] id: GO:0016740 name: transferase activity namespace: molecular_function def: "Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2." [ISBN:0198506732] xref: EC:2.-.-.- xref: Reactome:R-HSA-1483089 "PE is converted to PS by PTDSS2" xref: Reactome:R-HSA-1483186 "PC is converted to PS by PTDSS1" xref: Reactome:R-HSA-5668414 "TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK" xref: Reactome:R-HSA-8868783 "TSR3 transfers aminocarboxypropyl group from S-adenosylmethionine to N(1)-methylpseudouridine-1248 of 18SE rRNA yielding N(1)-methyl-N(3)-aminocarboxypropylpseudouridine-1248" is_a: GO:0003824 ! catalytic activity [Term] id: GO:0016772 name: transferase activity, transferring phosphorus-containing groups namespace: molecular_function def: "Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor)." [GOC:jl, ISBN:0198506732] xref: EC:2.7.-.- is_a: GO:0016740 ! transferase activity [Term] id: GO:0016787 name: hydrolase activity namespace: molecular_function def: "Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc." [ISBN:0198506732] xref: EC:3.-.-.- xref: Reactome:R-HSA-1236938 "Partial proteolysis of antigen in phagolysosomes" xref: Reactome:R-HSA-2029475 "Production of AA by iPLA2 upon FCGR activation" xref: Reactome:R-HSA-5694583 "ABHD4 hydrolyses NAPE" xref: Reactome:R-HSA-5695964 "ABHD14B hydrolyses PNPB" xref: Reactome:R-HSA-6786190 "CMBL hydrolyses OM to OLMS" xref: Reactome:R-HSA-6788295 "HDHD1:Mg2+ dephosphorylates PURIDP" xref: Reactome:R-HSA-8938314 "ENPPs hydrolyse CoA-SH to PPANT, PAP" xref: Reactome:R-HSA-8952137 "Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate" is_a: GO:0003824 ! catalytic activity [Term] id: GO:0016788 name: hydrolase activity, acting on ester bonds namespace: molecular_function def: "Catalysis of the hydrolysis of any ester bond." [GOC:jl] synonym: "esterase activity" EXACT [] xref: EC:3.1.-.- xref: Reactome:R-HSA-162729 "uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid" xref: Reactome:R-HSA-9023617 "Butyrylcholinesterase hydrolyzes acyl Ghrelin" xref: Reactome:R-HSA-9023619 "Platelet-activating factor acetylhydrolase (PLA2G7) hydrolyzes acyl Ghrelin" xref: Reactome:R-HSA-9749609 "BCHE hydrolyzes ASA-" is_a: GO:0016787 ! hydrolase activity [Term] id: GO:0017085 name: response to insecticide namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insecticide stimulus. Insecticides are chemicals used to kill insects." [GOC:curators] is_a: GO:0009636 ! response to toxic substance [Term] id: GO:0017126 name: nucleologenesis namespace: biological_process def: "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a nucleolus, a small, dense body one or more of which are present in the nucleus of eukaryotic cells." [GOC:jl, ISBN:0198506732] synonym: "nucleolus biogenesis" EXACT [] is_a: GO:0007000 ! nucleolus organization is_a: GO:0044085 ! cellular component biogenesis intersection_of: GO:0044085 ! cellular component biogenesis intersection_of: RO:0004008 GO:0005730 ! has primary output nucleolus relationship: RO:0004008 GO:0005730 ! has primary output nucleolus [Term] id: GO:0017145 name: stem cell division namespace: biological_process def: "The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or adult, that can undergo unlimited division and give rise to one or several different cell types." [GOC:jid, ISBN:0582227089] synonym: "stem cell renewal" EXACT [] is_a: GO:0051301 ! cell division intersection_of: GO:0051301 ! cell division intersection_of: RO:0004009 CL:0000034 ! has primary input stem cell relationship: RO:0004009 CL:0000034 ! has primary input stem cell [Term] id: GO:0017148 name: negative regulation of translation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA." [GOC:isa_complete] synonym: "down regulation of protein biosynthetic process" EXACT [] synonym: "down-regulation of protein biosynthetic process" EXACT [] synonym: "downregulation of protein biosynthetic process" EXACT [] synonym: "negative regulation of protein anabolism" EXACT [] synonym: "negative regulation of protein biosynthesis" EXACT [] synonym: "negative regulation of protein biosynthetic process" EXACT [] synonym: "negative regulation of protein formation" EXACT [] synonym: "negative regulation of protein synthesis" EXACT [] is_a: GO:0006417 ! regulation of translation is_a: GO:0010629 ! negative regulation of gene expression is_a: GO:0034249 ! negative regulation of amide metabolic process is_a: GO:0051248 ! negative regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006412 ! negatively regulates translation relationship: RO:0002212 GO:0006412 ! negatively regulates translation [Term] id: GO:0017157 name: regulation of exocytosis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of exocytosis." [GOC:go_curators] is_a: GO:0060627 ! regulation of vesicle-mediated transport is_a: GO:1903530 ! regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006887 ! regulates (processual) exocytosis relationship: RO:0002211 GO:0006887 ! regulates (processual) exocytosis [Term] id: GO:0018130 name: heterocycle biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings)." [ISBN:0198547684] synonym: "heterocycle anabolism" EXACT [] synonym: "heterocycle biosynthesis" EXACT [] synonym: "heterocycle formation" EXACT [] synonym: "heterocycle synthesis" EXACT [] is_a: GO:0044249 ! cellular biosynthetic process is_a: GO:0046483 ! heterocycle metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:5686 ! has primary output heterocyclic compound relationship: RO:0004008 CHEBI:5686 ! has primary output heterocyclic compound [Term] id: GO:0018958 name: phenol-containing compound metabolic process namespace: biological_process def: "The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring." [ISBN:0198506732] synonym: "carbolic acid metabolic process" EXACT [] synonym: "carbolic acid metabolism" EXACT [] synonym: "hydroxybenzene metabolic process" EXACT [] synonym: "hydroxybenzene metabolism" EXACT [] synonym: "phenol-containing compound metabolism" EXACT [] xref: UM-BBD_pathwayID:phe is_a: GO:0006725 ! cellular aromatic compound metabolic process is_a: GO:1901360 ! organic cyclic compound metabolic process is_a: GO:1901615 ! organic hydroxy compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:33853 ! has primary input or output phenols relationship: RO:0004007 CHEBI:33853 ! has primary input or output phenols [Term] id: GO:0018989 name: apolysis namespace: biological_process def: "The first process of molting, characterized by the detachment of the old cuticle from the underlying epidermal cells." [GOC:jl] xref: Wikipedia:Apolysis is_a: GO:0022404 ! molting cycle process relationship: BFO:0000050 GO:0007591 ! part of molting cycle, chitin-based cuticle [Term] id: GO:0019098 name: reproductive behavior namespace: biological_process def: "The specific behavior of an organism that is associated with reproduction." [GOC:jl, GOC:pr] synonym: "reproductive behavior in a multicellular organism" EXACT [] synonym: "reproductive behaviour" EXACT [] is_a: GO:0007610 ! behavior is_a: GO:0022414 ! reproductive process intersection_of: GO:0007610 ! behavior intersection_of: BFO:0000050 GO:0032504 ! part of multicellular organism reproduction relationship: BFO:0000050 GO:0032504 ! part of multicellular organism reproduction creation_date: 2012-09-19T16:01:37Z [Term] id: GO:0019216 name: regulation of lipid metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids." [GOC:go_curators] synonym: "regulation of lipid metabolism" EXACT [] is_a: GO:0080090 ! regulation of primary metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006629 ! regulates (processual) lipid metabolic process relationship: RO:0002211 GO:0006629 ! regulates (processual) lipid metabolic process [Term] id: GO:0019218 name: regulation of steroid metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving steroids." [GOC:go_curators] synonym: "regulation of steroid metabolism" EXACT [] is_a: GO:0019216 ! regulation of lipid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0008202 ! regulates (processual) steroid metabolic process relationship: RO:0002211 GO:0008202 ! regulates (processual) steroid metabolic process [Term] id: GO:0019219 name: regulation of nucleobase-containing compound metabolic process namespace: biological_process def: "Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:go_curators] synonym: "regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism" EXACT [] is_a: GO:0031323 ! regulation of cellular metabolic process is_a: GO:0051171 ! regulation of nitrogen compound metabolic process is_a: GO:0080090 ! regulation of primary metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006139 ! regulates (processual) nucleobase-containing compound metabolic process relationship: RO:0002211 GO:0006139 ! regulates (processual) nucleobase-containing compound metabolic process [Term] id: GO:0019220 name: regulation of phosphate metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates." [GOC:go_curators] synonym: "regulation of phosphate metabolism" EXACT [] is_a: GO:0051174 ! regulation of phosphorus metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006796 ! regulates (processual) phosphate-containing compound metabolic process relationship: RO:0002211 GO:0006796 ! regulates (processual) phosphate-containing compound metabolic process [Term] id: GO:0019222 name: regulation of metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." [GOC:go_curators] synonym: "regulation of metabolism" EXACT [] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0008152 ! regulates (processual) metabolic process relationship: RO:0002211 GO:0008152 ! regulates (processual) metabolic process [Term] id: GO:0019226 name: transmission of nerve impulse namespace: biological_process def: "The neurological system process in which a signal is transmitted through the nervous system by a combination of action potential propagation and synaptic transmission." [GOC:curators, ISBN:0815316194] synonym: "conduction of nerve impulse" EXACT [GOC:dph] synonym: "signal transmission along a neuron" EXACT [] is_a: GO:0050877 ! nervous system process relationship: BFO:0000050 GO:0007154 ! part of cell communication relationship: BFO:0000051 GO:0001508 ! has part action potential relationship: BFO:0000051 GO:0007268 ! has part chemical synaptic transmission [Term] id: GO:0019228 name: neuronal action potential namespace: biological_process def: "An action potential that occurs in a neuron." [GOC:dph, GOC:isa_complete, GOC:tb] is_a: GO:0001508 ! action potential intersection_of: GO:0001508 ! action potential intersection_of: BFO:0000066 CL:0000540 ! occurs in neuron relationship: BFO:0000050 GO:0019226 ! part of transmission of nerve impulse relationship: BFO:0000066 CL:0000540 ! occurs in neuron [Term] id: GO:0019233 name: sensory perception of pain namespace: biological_process def: "The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process." [GOC:curators] xref: Wikipedia:Nociception is_a: GO:0007600 ! sensory perception [Term] id: GO:0019318 name: hexose metabolic process namespace: biological_process def: "The chemical reactions and pathways involving a hexose, any monosaccharide with a chain of six carbon atoms in the molecule." [ISBN:0198506732] synonym: "hexose metabolism" EXACT [] is_a: GO:0005996 ! monosaccharide metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:18133 ! has primary input or output hexose relationship: RO:0004007 CHEBI:18133 ! has primary input or output hexose [Term] id: GO:0019319 name: hexose biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of hexose, any monosaccharide with a chain of six carbon atoms in the molecule." [ISBN:0198506732] synonym: "hexose anabolism" EXACT [] synonym: "hexose biosynthesis" EXACT [] synonym: "hexose formation" EXACT [] synonym: "hexose synthesis" EXACT [] is_a: GO:0019318 ! hexose metabolic process is_a: GO:0046364 ! monosaccharide biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:18133 ! has primary output hexose relationship: RO:0004008 CHEBI:18133 ! has primary output hexose [Term] id: GO:0019320 name: hexose catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of hexose, any monosaccharide with a chain of six carbon atoms in the molecule." [ISBN:0198506732] synonym: "hexose breakdown" EXACT [] synonym: "hexose catabolism" EXACT [] synonym: "hexose degradation" EXACT [] is_a: GO:0019318 ! hexose metabolic process is_a: GO:0046365 ! monosaccharide catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:18133 ! has primary input hexose relationship: RO:0004009 CHEBI:18133 ! has primary input hexose [Term] id: GO:0019336 name: phenol-containing compound catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring." [ISBN:0198506732] synonym: "phenol-containing compound breakdown" EXACT [] synonym: "phenol-containing compound catabolism" EXACT [] synonym: "phenol-containing compound degradation" EXACT [] xref: MetaCyc:PHENOLDEG-PWY is_a: GO:0018958 ! phenol-containing compound metabolic process is_a: GO:0019439 ! aromatic compound catabolic process is_a: GO:1901361 ! organic cyclic compound catabolic process is_a: GO:1901616 ! organic hydroxy compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:33853 ! has primary input phenols relationship: RO:0004009 CHEBI:33853 ! has primary input phenols [Term] id: GO:0019413 name: acetate biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of acetate, the anion of acetic acid." [GOC:go_curators] synonym: "acetate anabolism" EXACT [] synonym: "acetate biosynthesis" EXACT [] synonym: "acetate formation" EXACT [] synonym: "acetate synthesis" EXACT [] is_a: GO:0006083 ! acetate metabolic process is_a: GO:0072330 ! monocarboxylic acid biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:30089 ! has primary output acetate relationship: RO:0004008 CHEBI:30089 ! has primary output acetate [Term] id: GO:0019438 name: aromatic compound biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of aromatic compounds, any substance containing an aromatic carbon ring." [GOC:ai] synonym: "aromatic compound anabolism" EXACT [] synonym: "aromatic compound biosynthesis" EXACT [] synonym: "aromatic compound formation" EXACT [] synonym: "aromatic compound synthesis" EXACT [] is_a: GO:0006725 ! cellular aromatic compound metabolic process is_a: GO:0044249 ! cellular biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:33655 ! has primary output aromatic compound relationship: RO:0004008 CHEBI:33655 ! has primary output aromatic compound [Term] id: GO:0019439 name: aromatic compound catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of aromatic compounds, any substance containing an aromatic carbon ring." [GOC:ai] synonym: "aromatic compound breakdown" EXACT [] synonym: "aromatic compound catabolism" EXACT [] synonym: "aromatic compound degradation" EXACT [] is_a: GO:0006725 ! cellular aromatic compound metabolic process is_a: GO:0044248 ! cellular catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:33655 ! has primary input aromatic compound relationship: RO:0004009 CHEBI:33655 ! has primary input aromatic compound [Term] id: GO:0019538 name: protein metabolic process namespace: biological_process namespace: protein def: "The chemical reactions and pathways involving a protein. Includes protein modification." [GOC:ma] synonym: "cellular protein metabolic process" EXACT [] synonym: "cellular protein metabolism" EXACT [] synonym: "protein metabolic process and modification" EXACT [] synonym: "protein metabolism" EXACT [] synonym: "protein metabolism and modification" EXACT [] xref: Wikipedia:Protein_metabolism is_a: GO:0043170 ! macromolecule metabolic process is_a: GO:0044238 ! primary metabolic process is_a: GO:1901564 ! organonitrogen compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 PR:000000001 ! has primary input or output protein relationship: RO:0004007 PR:000000001 ! has primary input or output protein [Term] id: GO:0019614 name: catechol-containing compound catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent." [GOC:go_curators] is_a: GO:0009712 ! catechol-containing compound metabolic process is_a: GO:0019336 ! phenol-containing compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:33566 ! has primary input catechols relationship: RO:0004009 CHEBI:33566 ! has primary input catechols [Term] id: GO:0019725 name: cellular homeostasis namespace: biological_process def: "Any process involved in the maintenance of an internal steady state at the level of the cell." [GOC:isa_complete, GOC:jl, ISBN:0395825172] is_a: GO:0042592 ! homeostatic process intersection_of: GO:0042592 ! homeostatic process intersection_of: BFO:0000066 CL:0000000 ! occurs in cell disjoint_from: GO:0048872 ! homeostasis of number of cells relationship: BFO:0000066 CL:0000000 ! occurs in cell relationship: RO:0002160 NCBITaxon:131567 ! only in taxon cellular organisms relationship: RO:0002162 NCBITaxon:131567 {all_only="true"} ! in taxon cellular organisms [Term] id: GO:0019748 name: secondary metabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients." [GOC:go_curators] synonym: "secondary metabolism" EXACT [] synonym: "secondary metabolite metabolic process" EXACT [] synonym: "secondary metabolite metabolism" EXACT [] xref: Wikipedia:Secondary_metabolism is_a: GO:0008152 ! metabolic process [Term] id: GO:0019752 name: carboxylic acid metabolic process namespace: biological_process def: "The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-)." [ISBN:0198506732] synonym: "carboxylic acid metabolism" EXACT [] is_a: GO:0043436 ! oxoacid metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:29067 ! has primary input or output carboxylic acid anion relationship: RO:0004007 CHEBI:29067 ! has primary input or output carboxylic acid anion [Term] id: GO:0019755 name: one-carbon compound transport namespace: biological_process def: "The directed movement of one-carbon compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "one carbon compound transport" EXACT [] is_a: GO:0071702 ! organic substance transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:64708 ! has primary input one-carbon compound relationship: RO:0004009 CHEBI:64708 ! has primary input one-carbon compound [Term] id: GO:0019827 name: stem cell population maintenance namespace: biological_process def: "The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types." [GOC:mah, ISBN:0878932437] is_a: GO:0032501 ! multicellular organismal process is_a: GO:0098727 ! maintenance of cell number intersection_of: GO:0098727 ! maintenance of cell number intersection_of: RO:0012003 CL:0000034 ! acts on population of stem cell relationship: RO:0012003 CL:0000034 ! acts on population of stem cell [Term] id: GO:0019867 name: outer membrane namespace: cellular_component def: "The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites." [GOC:go_curators] is_a: GO:0016020 ! membrane [Term] id: GO:0019882 name: antigen processing and presentation namespace: biological_process def: "The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex." [GO_REF:0000022, GOC:add, ISBN:0781735149, PMID:15771591, PMID:15928678] synonym: "antigen presentation" EXACT [] synonym: "antigen processing" EXACT [] xref: Wikipedia:Antigen_presentation is_a: GO:0002376 ! immune system process [Term] id: GO:0019953 name: sexual reproduction namespace: biological_process def: "A type of reproduction that combines the genetic material of two gametes (such as a sperm or egg cell or fungal spores). The gametes have an haploid genome (with a single set of chromosomes, the product of a meiotic division) and combines with one another to produce a zygote (diploid)." [Wikipedia:Sexual_reproduction] xref: Wikipedia:Sexual_reproduction is_a: GO:0000003 ! reproduction [Term] id: GO:0021501 name: prechordal plate formation namespace: biological_process def: "The formation of the prechordal plate. The prechordal plate is a thickening of the endoderm at the cranial end of the primitive streak formed by the involution of Spemann's organizer cells. The prechordal plate and the notochord induce the formation of the neural plate from the overlying ectodermal cells." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0003063 ! results in formation of anatomical entity prechordal plate relationship: BFO:0000050 GO:0007399 ! part of nervous system development relationship: RO:0002297 UBERON:0003063 ! results in formation of anatomical entity prechordal plate [Term] id: GO:0021510 name: spinal cord development namespace: biological_process def: "The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002240 ! results in development of spinal cord relationship: BFO:0000050 GO:0007417 ! part of central nervous system development relationship: RO:0002296 UBERON:0002240 ! results in development of spinal cord [Term] id: GO:0021514 name: ventral spinal cord interneuron differentiation namespace: biological_process def: "The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of ventral spinal cord interneurons. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] is_a: GO:0021515 ! cell differentiation in spinal cord is_a: GO:0021953 ! central nervous system neuron differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: BFO:0000066 UBERON:0002240 ! occurs in spinal cord intersection_of: RO:0002315 CL:0000099 ! results in acquisition of features of interneuron relationship: BFO:0000050 GO:0021517 ! part of ventral spinal cord development relationship: RO:0002315 CL:0000099 ! results in acquisition of features of interneuron [Term] id: GO:0021515 name: cell differentiation in spinal cord namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: BFO:0000066 UBERON:0002240 ! occurs in spinal cord relationship: BFO:0000050 GO:0021510 ! part of spinal cord development relationship: BFO:0000066 UBERON:0002240 ! occurs in spinal cord [Term] id: GO:0021517 name: ventral spinal cord development namespace: biological_process def: "The process whose specific outcome is the progression of the ventral region of the spinal cord over time, from its formation to the mature structure. The neurons of the ventral region of the mature spinal cord participate in motor output." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002257 ! results in development of ventral horn of spinal cord relationship: BFO:0000050 GO:0021510 ! part of spinal cord development relationship: RO:0002296 UBERON:0002257 ! results in development of ventral horn of spinal cord [Term] id: GO:0021522 name: spinal cord motor neuron differentiation namespace: biological_process def: "The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of motor neurons. Motor neurons innervate an effector (muscle or glandular) tissue and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] is_a: GO:0021515 ! cell differentiation in spinal cord is_a: GO:0021953 ! central nervous system neuron differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0011001 ! results in acquisition of features of spinal cord motor neuron relationship: BFO:0000050 GO:0021517 ! part of ventral spinal cord development relationship: RO:0002315 CL:0011001 ! results in acquisition of features of spinal cord motor neuron [Term] id: GO:0021523 name: somatic motor neuron differentiation namespace: biological_process def: "The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of somatic motor neurons. Somatic motor neurons innervate skeletal muscle targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] is_a: GO:0021522 ! spinal cord motor neuron differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0005024 ! results in acquisition of features of somatomotor neuron relationship: RO:0002315 CL:0005024 ! results in acquisition of features of somatomotor neuron [Term] id: GO:0021532 name: neural tube patterning namespace: biological_process def: "The regionalization process that regulates the coordinated growth that establishes the non-random spatial arrangement of the neural tube." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0003002 ! regionalization relationship: BFO:0000050 GO:0021915 ! part of neural tube development [Term] id: GO:0021533 name: cell differentiation in hindbrain namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mature cells of the hindbrain. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: BFO:0000066 UBERON:0002028 ! occurs in hindbrain relationship: BFO:0000050 GO:0030902 ! part of hindbrain development relationship: BFO:0000066 UBERON:0002028 ! occurs in hindbrain relationship: RO:0002160 NCBITaxon:89593 ! only in taxon Craniata relationship: RO:0002162 NCBITaxon:89593 {all_only="true"} ! in taxon Craniata [Term] id: GO:0021534 name: cell proliferation in hindbrain namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0061351 ! neural precursor cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: BFO:0000066 UBERON:0002028 ! occurs in hindbrain relationship: BFO:0000050 GO:0030902 ! part of hindbrain development relationship: BFO:0000066 UBERON:0002028 ! occurs in hindbrain relationship: RO:0002160 NCBITaxon:89593 ! only in taxon Craniata relationship: RO:0002162 NCBITaxon:89593 {all_only="true"} ! in taxon Craniata [Term] id: GO:0021535 name: cell migration in hindbrain namespace: biological_process def: "The orderly movement of a cell that will reside in the hindbrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: BFO:0000066 UBERON:0002028 ! occurs in hindbrain relationship: BFO:0000050 GO:0030902 ! part of hindbrain development relationship: BFO:0000066 UBERON:0002028 ! occurs in hindbrain relationship: RO:0002160 NCBITaxon:89593 ! only in taxon Craniata relationship: RO:0002162 NCBITaxon:89593 {all_only="true"} ! in taxon Craniata [Term] id: GO:0021545 name: cranial nerve development namespace: biological_process def: "The process whose specific outcome is the progression of the cranial nerves over time, from its formation to the mature structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0021675 ! nerve development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001785 ! results in development of cranial nerve relationship: RO:0002296 UBERON:0001785 ! results in development of cranial nerve [Term] id: GO:0021546 name: rhombomere development namespace: biological_process def: "The process whose specific outcome is the progression of the rhombomere over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001892 ! results in development of rhombomere relationship: BFO:0000050 GO:0030902 ! part of hindbrain development relationship: RO:0002296 UBERON:0001892 ! results in development of rhombomere [Term] id: GO:0021547 name: midbrain-hindbrain boundary initiation namespace: biological_process def: "The regionalization process that gives rise to the midbrain-hindbrain boundary. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:isa_complete, GOC:jid, PMID:15541513] synonym: "MHB biosynthesis" EXACT [GOC:cls] synonym: "MHB formation" EXACT [GOC:cls] synonym: "midbrain-hindbrain boundary biosynthesis" EXACT [GOC:cls] synonym: "midbrain-hindbrain boundary formation" EXACT [GOC:cls] is_a: GO:0003002 ! regionalization is_a: GO:0048859 ! formation of anatomical boundary intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0003052 ! results in formation of anatomical entity midbrain-hindbrain boundary relationship: BFO:0000050 GO:0021999 ! part of neural plate anterior/posterior regionalization relationship: BFO:0000050 GO:0030917 ! part of midbrain-hindbrain boundary development relationship: RO:0002297 UBERON:0003052 ! results in formation of anatomical entity midbrain-hindbrain boundary [Term] id: GO:0021548 name: pons development namespace: biological_process def: "The process whose specific outcome is the progression of the pons over time, from its formation to the mature structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000988 ! results in development of pons relationship: BFO:0000050 GO:0022037 ! part of metencephalon development relationship: RO:0002296 UBERON:0000988 ! results in development of pons [Term] id: GO:0021550 name: medulla oblongata development namespace: biological_process def: "The process whose specific outcome is the progression of the medulla oblongata over time, from its formation to the mature structure. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001896 ! results in development of medulla oblongata relationship: BFO:0000050 GO:0030902 ! part of hindbrain development relationship: RO:0002296 UBERON:0001896 ! results in development of medulla oblongata [Term] id: GO:0021551 name: central nervous system morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the central nervous system is generated and organized. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0582227089] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001017 ! results in morphogenesis of central nervous system relationship: BFO:0000050 GO:0007417 ! part of central nervous system development relationship: RO:0002298 UBERON:0001017 ! results in morphogenesis of central nervous system [Term] id: GO:0021555 name: midbrain-hindbrain boundary morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the midbrain-hindbrain boundary is generated and organized. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15541513] synonym: "isthmus morphogenesis" EXACT [GOC:cls] synonym: "MHB morphogenesis" EXACT [GOC:cls] is_a: GO:0048598 ! embryonic morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003052 ! results in morphogenesis of midbrain-hindbrain boundary relationship: BFO:0000050 GO:0030917 ! part of midbrain-hindbrain boundary development relationship: RO:0002298 UBERON:0003052 ! results in morphogenesis of midbrain-hindbrain boundary [Term] id: GO:0021556 name: central nervous system formation namespace: biological_process def: "The process that gives rise to the central nervous system. This process pertains to the initial formation of a structure from unspecified parts. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0582227089] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0001017 ! results in formation of anatomical entity central nervous system relationship: BFO:0000050 GO:0021551 ! part of central nervous system morphogenesis relationship: RO:0002297 UBERON:0001017 ! results in formation of anatomical entity central nervous system [Term] id: GO:0021559 name: trigeminal nerve development namespace: biological_process def: "The process whose specific outcome is the progression of the trigeminal nerve over time, from its formation to the mature structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "cranial nerve 5 development" EXACT [GOC:cls] synonym: "cranial nerve V development" EXACT [GOC:cls] is_a: GO:0021545 ! cranial nerve development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001645 ! results in development of trigeminal nerve relationship: RO:0002296 UBERON:0001645 ! results in development of trigeminal nerve [Term] id: GO:0021575 name: hindbrain morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the hindbrain is generated and organized. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002028 ! results in morphogenesis of hindbrain relationship: BFO:0000050 GO:0030902 ! part of hindbrain development relationship: RO:0002298 UBERON:0002028 ! results in morphogenesis of hindbrain [Term] id: GO:0021576 name: hindbrain formation namespace: biological_process def: "The process that gives rise to the hindbrain. This process pertains to the initial formation of a structure from unspecified parts. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0002028 ! results in formation of anatomical entity hindbrain relationship: BFO:0000050 GO:0021575 ! part of hindbrain morphogenesis relationship: RO:0002297 UBERON:0002028 ! results in formation of anatomical entity hindbrain [Term] id: GO:0021578 name: hindbrain maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for the hindbrain to attain its fully functional state. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 UBERON:0002028 ! results in maturation of hindbrain relationship: BFO:0000050 GO:0021626 ! part of central nervous system maturation relationship: BFO:0000050 GO:0030902 ! part of hindbrain development relationship: RO:0002299 UBERON:0002028 ! results in maturation of hindbrain [Term] id: GO:0021579 name: medulla oblongata morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the medulla oblongata is generated and organized. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001896 ! results in morphogenesis of medulla oblongata relationship: BFO:0000050 GO:0021550 ! part of medulla oblongata development relationship: BFO:0000050 GO:0021575 ! part of hindbrain morphogenesis relationship: RO:0002298 UBERON:0001896 ! results in morphogenesis of medulla oblongata [Term] id: GO:0021580 name: medulla oblongata formation namespace: biological_process def: "The process that gives rise to the medulla oblongata. This process pertains to the initial formation of a structure from unspecified parts. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0001896 ! results in formation of anatomical entity medulla oblongata relationship: BFO:0000050 GO:0021576 ! part of hindbrain formation relationship: BFO:0000050 GO:0021579 ! part of medulla oblongata morphogenesis relationship: RO:0002297 UBERON:0001896 ! results in formation of anatomical entity medulla oblongata [Term] id: GO:0021582 name: medulla oblongata maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for the medulla oblongata to attain its fully functional state. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 UBERON:0001896 ! results in maturation of medulla oblongata relationship: BFO:0000050 GO:0021550 ! part of medulla oblongata development relationship: BFO:0000050 GO:0021578 ! part of hindbrain maturation relationship: RO:0002299 UBERON:0001896 ! results in maturation of medulla oblongata [Term] id: GO:0021583 name: pons morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the pons is generated and organized. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000988 ! results in morphogenesis of pons relationship: BFO:0000050 GO:0021548 ! part of pons development relationship: BFO:0000050 GO:0021575 ! part of hindbrain morphogenesis relationship: RO:0002298 UBERON:0000988 ! results in morphogenesis of pons [Term] id: GO:0021584 name: pons formation namespace: biological_process def: "The process that gives rise to the pons. This process pertains to the initial formation of a structure from unspecified parts. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0000988 ! results in formation of anatomical entity pons relationship: BFO:0000050 GO:0021576 ! part of hindbrain formation relationship: BFO:0000050 GO:0021583 ! part of pons morphogenesis relationship: RO:0002297 UBERON:0000988 ! results in formation of anatomical entity pons [Term] id: GO:0021586 name: pons maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for the pons to attain its fully functional state. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 UBERON:0000988 ! results in maturation of pons relationship: BFO:0000050 GO:0021548 ! part of pons development relationship: BFO:0000050 GO:0021578 ! part of hindbrain maturation relationship: RO:0002299 UBERON:0000988 ! results in maturation of pons [Term] id: GO:0021593 name: rhombomere morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the rhombomere is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001892 ! results in morphogenesis of rhombomere relationship: BFO:0000050 GO:0021546 ! part of rhombomere development relationship: RO:0002298 UBERON:0001892 ! results in morphogenesis of rhombomere [Term] id: GO:0021594 name: rhombomere formation namespace: biological_process def: "The process that gives rise to the rhombomere. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0001892 ! results in formation of anatomical entity rhombomere relationship: BFO:0000050 GO:0021593 ! part of rhombomere morphogenesis relationship: RO:0002297 UBERON:0001892 ! results in formation of anatomical entity rhombomere [Term] id: GO:0021602 name: cranial nerve morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the cranial nerves are generated and organized. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001785 ! results in morphogenesis of cranial nerve relationship: BFO:0000050 GO:0021545 ! part of cranial nerve development relationship: RO:0002298 UBERON:0001785 ! results in morphogenesis of cranial nerve [Term] id: GO:0021603 name: cranial nerve formation namespace: biological_process def: "The process that gives rise to the cranial nerves. This process pertains to the initial formation of a structure from unspecified parts. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0001785 ! results in formation of anatomical entity cranial nerve relationship: BFO:0000050 GO:0021602 ! part of cranial nerve morphogenesis relationship: RO:0002297 UBERON:0001785 ! results in formation of anatomical entity cranial nerve [Term] id: GO:0021605 name: cranial nerve maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for a cranial nerve to attain its fully functional state. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0021682 ! nerve maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 UBERON:0001785 ! results in maturation of cranial nerve relationship: BFO:0000050 GO:0021545 ! part of cranial nerve development relationship: RO:0002299 UBERON:0001785 ! results in maturation of cranial nerve [Term] id: GO:0021626 name: central nervous system maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for the central nervous system to attain its fully functional state. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0582227089] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 UBERON:0001017 ! results in maturation of central nervous system relationship: BFO:0000050 GO:0007417 ! part of central nervous system development relationship: RO:0002299 UBERON:0001017 ! results in maturation of central nervous system [Term] id: GO:0021635 name: trigeminal nerve maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for the trigeminal nerve to attain its fully functional state. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0021605 ! cranial nerve maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 UBERON:0001645 ! results in maturation of trigeminal nerve relationship: BFO:0000050 GO:0021559 ! part of trigeminal nerve development relationship: RO:0002299 UBERON:0001645 ! results in maturation of trigeminal nerve [Term] id: GO:0021636 name: trigeminal nerve morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the trigeminal nerve is generated and organized. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0021602 ! cranial nerve morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001645 ! results in morphogenesis of trigeminal nerve relationship: BFO:0000050 GO:0021559 ! part of trigeminal nerve development relationship: RO:0002298 UBERON:0001645 ! results in morphogenesis of trigeminal nerve [Term] id: GO:0021638 name: trigeminal nerve formation namespace: biological_process def: "The process that gives rise to the trigeminal nerve. This process pertains to the initial formation of a structure from unspecified parts. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0021603 ! cranial nerve formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0001645 ! results in formation of anatomical entity trigeminal nerve relationship: BFO:0000050 GO:0021636 ! part of trigeminal nerve morphogenesis relationship: RO:0002297 UBERON:0001645 ! results in formation of anatomical entity trigeminal nerve [Term] id: GO:0021654 name: rhombomere boundary formation namespace: biological_process def: "The process that gives rise to a rhombomere boundary. This process pertains to the initial formation of a boundary delimiting a rhombomere. Rhombomeres are transverse segments of the developing rhombencephalon that are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0048859 ! formation of anatomical boundary intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0018239 ! results in formation of anatomical entity rhombomere boundary relationship: BFO:0000050 GO:0021594 ! part of rhombomere formation relationship: RO:0002297 UBERON:0018239 ! results in formation of anatomical entity rhombomere boundary [Term] id: GO:0021675 name: nerve development namespace: biological_process def: "The process whose specific outcome is the progression of a nerve over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001021 ! results in development of nerve relationship: BFO:0000050 GO:0007399 ! part of nervous system development relationship: RO:0002296 UBERON:0001021 ! results in development of nerve [Term] id: GO:0021682 name: nerve maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for a nerve to attain its fully functional state." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 UBERON:0001021 ! results in maturation of nerve relationship: BFO:0000050 GO:0021675 ! part of nerve development relationship: RO:0002299 UBERON:0001021 ! results in maturation of nerve [Term] id: GO:0021700 name: developmental maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure, cell or cellular component to attain its fully functional state." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0032502 ! developmental process [Term] id: GO:0021703 name: locus ceruleus development namespace: biological_process def: "The process whose specific outcome is the progression of the locus ceruleus over time, from its formation to the mature structure. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "locus caeruleus development" EXACT [] synonym: "locus coeruleus development" EXACT [] is_a: GO:0048857 ! neural nucleus development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002148 ! results in development of locus ceruleus relationship: BFO:0000050 GO:0021548 ! part of pons development relationship: RO:0002296 UBERON:0002148 ! results in development of locus ceruleus [Term] id: GO:0021704 name: locus ceruleus morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the locus ceruleus is generated and organized. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002148 ! results in morphogenesis of locus ceruleus relationship: BFO:0000050 GO:0021583 ! part of pons morphogenesis relationship: BFO:0000050 GO:0021703 ! part of locus ceruleus development relationship: RO:0002298 UBERON:0002148 ! results in morphogenesis of locus ceruleus [Term] id: GO:0021705 name: locus ceruleus formation namespace: biological_process def: "The process that gives rise to the locus ceruleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0002148 ! results in formation of anatomical entity locus ceruleus relationship: BFO:0000050 GO:0021584 ! part of pons formation relationship: BFO:0000050 GO:0021704 ! part of locus ceruleus morphogenesis relationship: RO:0002297 UBERON:0002148 ! results in formation of anatomical entity locus ceruleus [Term] id: GO:0021706 name: locus ceruleus maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for the locus ceruleus to attain its fully functional state. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 UBERON:0002148 ! results in maturation of locus ceruleus relationship: BFO:0000050 GO:0021586 ! part of pons maturation relationship: BFO:0000050 GO:0021703 ! part of locus ceruleus development relationship: RO:0002299 UBERON:0002148 ! results in maturation of locus ceruleus [Term] id: GO:0021718 name: superior olivary nucleus development namespace: biological_process def: "The process whose specific outcome is the progression of the superior olivary nucleus over time, from its formation to the mature structure. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0048857 ! neural nucleus development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0007247 ! results in development of nucleus of superior olivary complex relationship: BFO:0000050 GO:0021548 ! part of pons development relationship: RO:0002296 UBERON:0007247 ! results in development of nucleus of superior olivary complex [Term] id: GO:0021719 name: superior olivary nucleus morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the superior olivary nucleus is generated and organized. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0007247 ! results in morphogenesis of nucleus of superior olivary complex relationship: BFO:0000050 GO:0021583 ! part of pons morphogenesis relationship: BFO:0000050 GO:0021718 ! part of superior olivary nucleus development relationship: RO:0002298 UBERON:0007247 ! results in morphogenesis of nucleus of superior olivary complex [Term] id: GO:0021720 name: superior olivary nucleus formation namespace: biological_process def: "The process that gives rise to the superior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0007247 ! results in formation of anatomical entity nucleus of superior olivary complex relationship: BFO:0000050 GO:0021584 ! part of pons formation relationship: BFO:0000050 GO:0021719 ! part of superior olivary nucleus morphogenesis relationship: RO:0002297 UBERON:0007247 ! results in formation of anatomical entity nucleus of superior olivary complex [Term] id: GO:0021722 name: superior olivary nucleus maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for the superior olivary nucleus to attain its fully functional state. The superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 UBERON:0007247 ! results in maturation of nucleus of superior olivary complex relationship: BFO:0000050 GO:0021586 ! part of pons maturation relationship: BFO:0000050 GO:0021718 ! part of superior olivary nucleus development relationship: RO:0002299 UBERON:0007247 ! results in maturation of nucleus of superior olivary complex [Term] id: GO:0021732 name: midbrain-hindbrain boundary maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15541513] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 UBERON:0003052 ! results in maturation of midbrain-hindbrain boundary relationship: BFO:0000050 GO:0030917 ! part of midbrain-hindbrain boundary development relationship: RO:0002299 UBERON:0003052 ! results in maturation of midbrain-hindbrain boundary [Term] id: GO:0021751 name: salivary nucleus development namespace: biological_process def: "The process whose specific outcome is the progression of a salivary nucleus over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0048857 ! neural nucleus development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004133 ! results in development of salivatory nucleus relationship: BFO:0000050 GO:0021548 ! part of pons development relationship: RO:0002296 UBERON:0004133 ! results in development of salivatory nucleus [Term] id: GO:0021753 name: superior salivary nucleus development namespace: biological_process def: "The process whose specific outcome is the progression of the superior salivary nucleus over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0021751 ! salivary nucleus development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002149 ! results in development of superior salivatory nucleus relationship: RO:0002296 UBERON:0002149 ! results in development of superior salivatory nucleus [Term] id: GO:0021782 name: glial cell development namespace: biological_process def: "The process aimed at the progression of a glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000125 ! results in development of glial cell relationship: BFO:0000050 GO:0010001 ! part of glial cell differentiation relationship: RO:0002296 CL:0000125 ! results in development of glial cell [Term] id: GO:0021903 name: rostrocaudal neural tube patterning namespace: biological_process def: "The process in which the neural tube is divided into specific regions along the rostrocaudal axis." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] is_a: GO:0009952 ! anterior/posterior pattern specification relationship: BFO:0000050 GO:0021532 ! part of neural tube patterning [Term] id: GO:0021906 name: hindbrain-spinal cord boundary formation namespace: biological_process def: "The process whose specific outcome is the formation of the hindbrain-spinal cord boundary." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] is_a: GO:0048859 ! formation of anatomical boundary intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0005076 ! results in formation of anatomical entity hindbrain-spinal cord boundary relationship: BFO:0000050 GO:0021903 ! part of rostrocaudal neural tube patterning relationship: RO:0002297 UBERON:0005076 ! results in formation of anatomical entity hindbrain-spinal cord boundary [Term] id: GO:0021915 name: neural tube development namespace: biological_process def: "The process whose specific outcome is the progression of the neural tube over time, from its formation to the mature structure. The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0035295 ! tube development is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001049 ! results in development of neural tube relationship: BFO:0000050 GO:0007399 ! part of nervous system development relationship: BFO:0000050 GO:0043009 ! part of chordate embryonic development relationship: RO:0002296 UBERON:0001049 ! results in development of neural tube [Term] id: GO:0021953 name: central nervous system neuron differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the central nervous system." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0030182 ! neuron differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:2000029 ! results in acquisition of features of central nervous system neuron relationship: BFO:0000050 GO:0007417 ! part of central nervous system development relationship: RO:0002315 CL:2000029 ! results in acquisition of features of central nervous system neuron [Term] id: GO:0021954 name: central nervous system neuron development namespace: biological_process def: "The process whose specific outcome is the progression of a neuron whose cell body is located in the central nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0048666 ! neuron development intersection_of: GO:0048468 ! cell development intersection_of: RO:0002296 CL:2000029 ! results in development of central nervous system neuron relationship: BFO:0000050 GO:0021953 ! part of central nervous system neuron differentiation relationship: RO:0002296 CL:2000029 ! results in development of central nervous system neuron [Term] id: GO:0021990 name: neural plate formation namespace: biological_process def: "The formation of the flat, thickened layer of ectodermal cells known as the neural plate. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0878932437, ISBN:0878932585, PMID:15806586] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0003075 ! results in formation of anatomical entity neural plate relationship: BFO:0000050 GO:0001839 ! part of neural plate morphogenesis relationship: RO:0002297 UBERON:0003075 ! results in formation of anatomical entity neural plate [Term] id: GO:0021999 name: neural plate anterior/posterior regionalization namespace: biological_process def: "The process that regulates the coordinated growth and differentiation that establishes the non-random anterior-posterior spatial arrangement of the neural plate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0009952 ! anterior/posterior pattern specification is_a: GO:0060897 ! neural plate regionalization [Term] id: GO:0022008 name: neurogenesis namespace: biological_process def: "Generation of cells within the nervous system." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] xref: Wikipedia:Neurogenesis is_a: GO:0030154 ! cell differentiation relationship: BFO:0000050 GO:0007399 ! part of nervous system development [Term] id: GO:0022009 name: central nervous system vasculogenesis namespace: biological_process def: "The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes in the central nervous system. The capillary endothelial cells in the brain are specialized to form the blood-brain barrier." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0001570 ! vasculogenesis intersection_of: GO:0001570 ! vasculogenesis intersection_of: RO:0002299 UBERON:0001017 ! results in maturation of central nervous system relationship: RO:0002299 UBERON:0001017 ! results in maturation of central nervous system [Term] id: GO:0022035 name: rhombomere cell migration namespace: biological_process def: "The movement of a cell within a rhombomere. This process is known to occur as an early step in the generation of anatomical structure from a rhombomere." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15629700] is_a: GO:0021535 ! cell migration in hindbrain intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002344 UBERON:0001892 ! results in transport to from or in rhombomere relationship: BFO:0000050 GO:0021546 ! part of rhombomere development relationship: RO:0002344 UBERON:0001892 ! results in transport to from or in rhombomere [Term] id: GO:0022037 name: metencephalon development namespace: biological_process def: "The process whose specific outcome is the progression of the metencephalon over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001895 ! results in development of metencephalon relationship: BFO:0000050 GO:0030902 ! part of hindbrain development relationship: RO:0002296 UBERON:0001895 ! results in development of metencephalon [Term] id: GO:0022402 name: cell cycle process namespace: biological_process def: "The cellular process that ensures successive accurate and complete genome replication and chromosome segregation." [GOC:isa_complete, GOC:mtg_cell_cycle] is_a: GO:0009987 ! cellular process intersection_of: GO:0009987 ! cellular process intersection_of: BFO:0000050 GO:0007049 ! part of cell cycle relationship: BFO:0000050 GO:0007049 ! part of cell cycle [Term] id: GO:0022404 name: molting cycle process namespace: biological_process def: "A multicellular organismal process involved in the periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin." [GOC:isa_complete] is_a: GO:0032501 ! multicellular organismal process relationship: BFO:0000050 GO:0042303 ! part of molting cycle [Term] id: GO:0022406 name: membrane docking namespace: biological_process def: "The initial attachment of a membrane or protein to a target membrane. Docking requires only that the proteins come close enough to interact and adhere." [GOC:isa_complete, PMID:27875684] is_a: GO:0009987 ! cellular process [Term] id: GO:0022407 name: regulation of cell-cell adhesion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of attachment of a cell to another cell." [GOC:isa_complete] is_a: GO:0030155 ! regulation of cell adhesion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0098609 ! regulates (processual) cell-cell adhesion relationship: RO:0002211 GO:0098609 ! regulates (processual) cell-cell adhesion [Term] id: GO:0022408 name: negative regulation of cell-cell adhesion namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of cell adhesion to another cell." [GOC:isa_complete] synonym: "down regulation of cell-cell adhesion" EXACT [] synonym: "down-regulation of cell-cell adhesion" EXACT [] synonym: "downregulation of cell-cell adhesion" EXACT [] is_a: GO:0007162 ! negative regulation of cell adhesion is_a: GO:0022407 ! regulation of cell-cell adhesion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0098609 ! negatively regulates cell-cell adhesion relationship: RO:0002212 GO:0098609 ! negatively regulates cell-cell adhesion [Term] id: GO:0022409 name: positive regulation of cell-cell adhesion namespace: biological_process def: "Any process that activates or increases the rate or extent of cell adhesion to another cell." [GOC:isa_complete] synonym: "up regulation of cell-cell adhesion" EXACT [] synonym: "up-regulation of cell-cell adhesion" EXACT [] synonym: "upregulation of cell-cell adhesion" EXACT [] is_a: GO:0022407 ! regulation of cell-cell adhesion is_a: GO:0045785 ! positive regulation of cell adhesion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0098609 ! positively regulates cell-cell adhesion relationship: RO:0002213 GO:0098609 ! positively regulates cell-cell adhesion [Term] id: GO:0022411 name: cellular component disassembly namespace: biological_process def: "A cellular process that results in the breakdown of a cellular component." [GOC:isa_complete] synonym: "cell structure disassembly" EXACT [] synonym: "cellular component disassembly at cellular level" EXACT [] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0009987 ! cellular process intersection_of: RO:0002590 GO:0005575 ! results in disassembly of cellular_component disjoint_from: GO:0022607 ! cellular component assembly relationship: RO:0002590 GO:0005575 ! results in disassembly of cellular_component [Term] id: GO:0022412 name: cellular process involved in reproduction in multicellular organism namespace: biological_process def: "A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular organism." [GOC:isa_complete] synonym: "reproductive cellular process in multicellular organism" EXACT [] is_a: GO:0009987 ! cellular process is_a: GO:0022414 ! reproductive process intersection_of: GO:0009987 ! cellular process intersection_of: BFO:0000050 GO:0032504 ! part of multicellular organism reproduction relationship: BFO:0000050 GO:0032504 ! part of multicellular organism reproduction [Term] id: GO:0022414 name: reproductive process namespace: biological_process def: "A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents." [GOC:dph, GOC:isa_complete] is_a: GO:0008150 ! biological_process intersection_of: GO:0008150 ! biological_process intersection_of: BFO:0000050 GO:0000003 ! part of reproduction relationship: BFO:0000050 GO:0000003 ! part of reproduction creation_date: 2012-09-19T15:56:06Z [Term] id: GO:0022600 name: digestive system process namespace: biological_process def: "A physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." [GOC:isa_complete, GOC:jid, GOC:mtg_cardio] is_a: GO:0003008 ! system process intersection_of: GO:0003008 ! system process intersection_of: BFO:0000050 GO:0007586 ! part of digestion relationship: BFO:0000050 GO:0007586 ! part of digestion [Term] id: GO:0022602 name: ovulation cycle process namespace: biological_process def: "A process involved in the sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years." [GOC:isa_complete] is_a: GO:0022414 ! reproductive process is_a: GO:0048511 ! rhythmic process relationship: BFO:0000050 GO:0042698 ! part of ovulation cycle relationship: RO:0002160 NCBITaxon:33208 ! only in taxon Metazoa relationship: RO:0002162 NCBITaxon:33208 {all_only="true"} ! in taxon Metazoa [Term] id: GO:0022603 name: regulation of anatomical structure morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of anatomical structure morphogenesis." [GOC:mah] synonym: "regulation of morphogenesis" EXACT [] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0009653 ! regulates (processual) anatomical structure morphogenesis relationship: RO:0002211 GO:0009653 ! regulates (processual) anatomical structure morphogenesis [Term] id: GO:0022604 name: regulation of cell morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process in which the shape of a cell is generated and organized." [GOC:isa_complete] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0000902 ! regulates (processual) cell morphogenesis relationship: RO:0002211 GO:0000902 ! regulates (processual) cell morphogenesis [Term] id: GO:0022607 name: cellular component assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a cellular component." [GOC:isa_complete] synonym: "cell structure assembly" EXACT [] synonym: "cellular component assembly at cellular level" EXACT [] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0009987 ! cellular process intersection_of: RO:0002588 GO:0005575 ! results in assembly of cellular_component relationship: BFO:0000050 GO:0044085 ! part of cellular component biogenesis relationship: RO:0002588 GO:0005575 ! results in assembly of cellular_component [Term] id: GO:0022612 name: gland morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a gland are generated and organized." [GOC:isa_complete] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002530 ! results in morphogenesis of gland relationship: BFO:0000050 GO:0048732 ! part of gland development relationship: RO:0002298 UBERON:0002530 ! results in morphogenesis of gland [Term] id: GO:0022613 name: ribonucleoprotein complex biogenesis namespace: biological_process def: "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a complex containing RNA and proteins. Includes the biosynthesis of the constituent RNA and protein molecules, and those macromolecular modifications that are involved in synthesis or assembly of the ribonucleoprotein complex." [GOC:isa_complete, GOC:mah] synonym: "ribonucleoprotein complex biogenesis and assembly" EXACT [GOC:mah] synonym: "RNA-protein complex biogenesis" EXACT [GOC:mah] is_a: GO:0044085 ! cellular component biogenesis [Term] id: GO:0022617 name: extracellular matrix disassembly namespace: biological_process def: "A process that results in the breakdown of the extracellular matrix." [GOC:jid] is_a: GO:0022411 ! cellular component disassembly is_a: GO:0030198 ! extracellular matrix organization intersection_of: GO:0022411 ! cellular component disassembly intersection_of: RO:0002590 GO:0031012 ! results in disassembly of extracellular matrix relationship: RO:0002590 GO:0031012 ! results in disassembly of extracellular matrix [Term] id: GO:0022618 name: protein-RNA complex assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex." [GOC:jl] synonym: "ribonucleoprotein complex assembly" EXACT [] synonym: "RNA-protein complex assembly" EXACT [] synonym: "RNP complex assembly" EXACT [] is_a: GO:0065003 ! protein-containing complex assembly is_a: GO:0071826 ! protein-RNA complex organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:1990904 ! results in assembly of ribonucleoprotein complex relationship: BFO:0000050 GO:0022613 ! part of ribonucleoprotein complex biogenesis relationship: RO:0002588 GO:1990904 ! results in assembly of ribonucleoprotein complex [Term] id: GO:0022804 name: active transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction." [GOC:mtg_transport, ISBN:0815340729] synonym: "active carrier activity" EXACT [] synonym: "carrier activity" EXACT [] synonym: "permease activity" EXACT [] synonym: "pump activity" EXACT [] is_a: GO:0022857 ! transmembrane transporter activity [Term] id: GO:0022853 name: active monoatomic ion transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of an ion from one side of a membrane to the other up the solute's concentration gradient. This is carried out by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction." [GOC:mtg_transport, ISBN:0815340729] is_a: GO:0015075 ! monoatomic ion transmembrane transporter activity is_a: GO:0022804 ! active transmembrane transporter activity intersection_of: GO:0022804 ! active transmembrane transporter activity intersection_of: RO:0004009 CHEBI:24867 ! has primary input monoatomic ion [Term] id: GO:0022857 name: transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other." [GOC:jid, GOC:mtg_transport, ISBN:0815340729] xref: Reactome:R-HSA-1236947 "Egress of internalized antigen to the cytosol via sec61" xref: Reactome:R-HSA-429036 "SLC2A9 transports Fru, Glc, urate" xref: Reactome:R-HSA-5638209 "Defective SLC2A9 does not transport Fru, Glc, urate" xref: Reactome:R-HSA-5671707 "Fe3+ dissociates from SLC22A17:LCN2:2,5DHBA" xref: Reactome:R-HSA-6784434 "An unknown carrier transports cytosolic glyoxylate to the peroxisome" xref: Reactome:R-HSA-6784436 "An unknown carrier transports mitochondrial glyoxylate to the cytosol" is_a: GO:0005215 ! transporter activity intersection_of: GO:0005215 ! transporter activity intersection_of: RO:0002342 GO:0016020 ! results in transport across membrane relationship: BFO:0000050 GO:0055085 ! part of transmembrane transport relationship: RO:0002342 GO:0016020 ! results in transport across membrane [Term] id: GO:0022884 name: macromolecule transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of a macromolecule from one side of a membrane to the other." [GOC:mtg_transport, ISBN:0815340729] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:33694 ! has primary input biomacromolecule relationship: RO:0004009 CHEBI:33694 ! has primary input biomacromolecule [Term] id: GO:0022890 name: inorganic cation transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of inorganic cations from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] is_a: GO:0015318 ! inorganic molecular entity transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:36915 ! has primary input inorganic cation relationship: RO:0004009 CHEBI:36915 ! has primary input inorganic cation [Term] id: GO:0022898 name: regulation of transmembrane transporter activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of transmembrane transporter activity." [GOC:dph, GOC:mtg_cardio, GOC:mtg_transport] is_a: GO:0032409 ! regulation of transporter activity is_a: GO:0034762 ! regulation of transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0022857 ! regulates (processual) transmembrane transporter activity relationship: RO:0002211 GO:0022857 ! regulates (processual) transmembrane transporter activity [Term] id: GO:0023019 name: signal transduction involved in regulation of gene expression namespace: biological_process def: "Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a signal is released and/or conveyed from one location to another." [GOC:mtg_signal] is_a: GO:0007165 ! signal transduction intersection_of: GO:0007165 ! signal transduction intersection_of: BFO:0000050 GO:0010468 ! part of regulation of gene expression relationship: BFO:0000050 GO:0010468 ! part of regulation of gene expression creation_date: 2010-02-16T09:30:50Z [Term] id: GO:0023051 name: regulation of signaling namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a signaling process." [GOC:mtg_signal] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0023052 ! regulates (processual) signaling relationship: RO:0002211 GO:0023052 ! regulates (processual) signaling creation_date: 2010-02-16T09:30:50Z [Term] id: GO:0023052 name: signaling namespace: biological_process def: "The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered." [GOC:mtg_signal, GOC:mtg_signaling_feb11, GOC:signaling] synonym: "biological signaling" EXACT [] synonym: "signaling process" EXACT [] synonym: "signalling" EXACT [] is_a: GO:0050789 ! regulation of biological process creation_date: 2010-02-16T09:30:50Z [Term] id: GO:0023056 name: positive regulation of signaling namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of a signaling process." [GOC:mtg_signal] synonym: "positive regulation of signalling process" EXACT [GOC:mah] is_a: GO:0023051 ! regulation of signaling is_a: GO:0048518 ! positive regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0023052 ! positively regulates signaling relationship: RO:0002213 GO:0023052 ! positively regulates signaling creation_date: 2010-02-16T09:30:50Z [Term] id: GO:0023057 name: negative regulation of signaling namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a signaling process." [GOC:mtg_signal] is_a: GO:0023051 ! regulation of signaling is_a: GO:0048519 ! negative regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0023052 ! negatively regulates signaling relationship: RO:0002212 GO:0023052 ! negatively regulates signaling creation_date: 2010-02-16T09:30:50Z [Term] id: GO:0023061 name: signal release namespace: biological_process def: "The process in which a signal is secreted or discharged into the extracellular medium from a cellular source." [GOC:mtg_signal] synonym: "signal secretion" EXACT [GOC:bf] is_a: GO:0032940 ! secretion by cell intersection_of: GO:0032940 ! secretion by cell intersection_of: BFO:0000050 GO:0007267 ! part of cell-cell signaling relationship: BFO:0000050 GO:0007267 ! part of cell-cell signaling creation_date: 2010-02-16T09:30:50Z [Term] id: GO:0030001 name: metal ion transport namespace: biological_process def: "The directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] is_a: GO:0006812 ! monoatomic cation transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:25213 ! has primary input metal cation relationship: RO:0004009 CHEBI:25213 ! has primary input metal cation creation_date: 2009-07-31T01:07:46Z [Term] id: GO:0030010 name: establishment of cell polarity namespace: biological_process def: "The specification and formation of anisotropic intracellular organization or cell growth patterns." [GOC:mah] synonym: "cell polarization" EXACT [] is_a: GO:0007163 ! establishment or maintenance of cell polarity [Term] id: GO:0030016 name: myofibril namespace: cellular_component def: "The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism." [ISBN:0815316194] xref: Wikipedia:Myofibril is_a: GO:0043292 ! contractile fiber intersection_of: GO:0043292 ! contractile fiber intersection_of: BFO:0000050 CL:0000737 ! part of striated muscle cell relationship: BFO:0000050 CL:0000737 ! part of striated muscle cell [Term] id: GO:0030017 name: sarcomere namespace: cellular_component def: "The repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." [ISBN:0815316194] xref: Wikipedia:Sarcomere is_a: GO:0110165 ! cellular anatomical entity is_a: UBERON:0004120 ! mesoderm-derived structure relationship: BFO:0000050 GO:0030016 ! part of myofibril [Term] id: GO:0030029 name: actin filament-based process namespace: biological_process def: "Any cellular process that depends upon or alters the actin cytoskeleton, that part of the cytoskeleton comprising actin filaments and their associated proteins." [GOC:mah] is_a: GO:0009987 ! cellular process intersection_of: GO:0009987 ! cellular process intersection_of: RO:0002608 GO:0005884 ! process has causal agent actin filament relationship: RO:0002608 GO:0005884 ! process has causal agent actin filament [Term] id: GO:0030030 name: cell projection organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, GOC:mah, http://www.cogsci.princeton.edu/~wn/] synonym: "cell projection organisation" EXACT [] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0042995 ! results in organization of cell projection relationship: RO:0002592 GO:0042995 ! results in organization of cell projection [Term] id: GO:0030031 name: cell projection assembly namespace: biological_process def: "Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, GOC:mah, http://www.cogsci.princeton.edu/~wn/] synonym: "formation of a cell surface projection" EXACT [] is_a: GO:0022607 ! cellular component assembly is_a: GO:0030030 ! cell projection organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0042995 ! results in assembly of cell projection relationship: RO:0002588 GO:0042995 ! results in assembly of cell projection [Term] id: GO:0030033 name: microvillus assembly namespace: biological_process def: "Formation of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell." [GOC:mah, ISBN:0815316194] is_a: GO:0032528 ! microvillus organization is_a: GO:0120031 ! plasma membrane bounded cell projection assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0005902 ! results in assembly of microvillus relationship: RO:0002588 GO:0005902 ! results in assembly of microvillus [Term] id: GO:0030036 name: actin cytoskeleton organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins." [GOC:dph, GOC:jl, GOC:mah] synonym: "actin cytoskeleton organisation" EXACT [] is_a: GO:0007010 ! cytoskeleton organization is_a: GO:0030029 ! actin filament-based process intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0015629 ! results in organization of actin cytoskeleton relationship: RO:0002592 GO:0015629 ! results in organization of actin cytoskeleton [Term] id: GO:0030048 name: actin filament-based movement namespace: biological_process def: "Movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins." [GOC:BHF, GOC:mah] is_a: GO:0030029 ! actin filament-based process [Term] id: GO:0030050 name: vesicle transport along actin filament namespace: biological_process def: "Movement of a vesicle along an actin filament, mediated by motor proteins." [GOC:mah] is_a: GO:0030048 ! actin filament-based movement is_a: GO:0099515 ! actin filament-based transport is_a: GO:0099518 ! vesicle cytoskeletal trafficking intersection_of: GO:0046907 ! intracellular transport intersection_of: RO:0002341 GO:0005884 ! results in transport along actin filament intersection_of: RO:0004009 GO:0031982 ! has primary input vesicle [Term] id: GO:0030054 name: cell junction namespace: cellular_component def: "A cellular component that forms a specialized region of connection between two or more cells, or between a cell and the extracellular matrix, or between two membrane-bound components of a cell, such as flagella." [GOC:aruk, GOC:bc, GOC:mah, http://www.vivo.colostate.edu/hbooks/cmb/cells/pmemb/junctions_a.html, ISBN:0198506732, PMID:26820516, PMID:28096264] xref: Wikipedia:Cell_junction is_a: GO:0110165 ! cellular anatomical entity [Term] id: GO:0030072 name: peptide hormone secretion namespace: biological_process def: "The regulated release of a peptide hormone from a cell." [GOC:mah] is_a: GO:0002790 ! peptide secretion is_a: GO:0046879 ! hormone secretion intersection_of: GO:0046903 ! secretion intersection_of: RO:0004009 CHEBI:25905 ! has primary input peptide hormone relationship: RO:0004009 CHEBI:25905 ! has primary input peptide hormone [Term] id: GO:0030073 name: insulin secretion namespace: biological_process def: "The regulated release of proinsulin from secretory granules accompanied by cleavage of proinsulin to form mature insulin. In vertebrates, insulin is secreted from B granules in the B cells of the vertebrate pancreas and from insulin-producing cells in insects." [GOC:mah, ISBN:0198506732] is_a: GO:0009306 ! protein secretion is_a: GO:0030072 ! peptide hormone secretion intersection_of: GO:0046903 ! secretion intersection_of: RO:0004009 PR:000009054 ! has primary input insulin gene translation product relationship: RO:0002160 NCBITaxon:6072 ! only in taxon Eumetazoa relationship: RO:0002162 NCBITaxon:6072 {all_only="true"} ! in taxon Eumetazoa relationship: RO:0004009 PR:000009054 ! has primary input insulin gene translation product [Term] id: GO:0030097 name: hemopoiesis namespace: biological_process def: "The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates." [GOC:dgh, ISBN:0198506732] synonym: "blood cell biosynthesis" EXACT [] synonym: "blood cell formation" EXACT [] synonym: "haemopoiesis" EXACT [] synonym: "hematopoiesis" EXACT [] xref: Wikipedia:Haematopoiesis is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000988 ! results in development of hematopoietic cell relationship: RO:0002296 CL:0000988 ! results in development of hematopoietic cell [Term] id: GO:0030098 name: lymphocyte differentiation namespace: biological_process def: "The process in which a relatively unspecialized precursor cell acquires specialized features of a lymphocyte. A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin." [CL:0000542, GOC:go_curators] synonym: "lymphocyte cell differentiation" EXACT [] synonym: "lymphocytic blood cell differentiation" EXACT [] is_a: GO:0046649 ! lymphocyte activation is_a: GO:1903131 ! mononuclear cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000542 ! results in acquisition of features of lymphocyte relationship: RO:0002315 CL:0000542 ! results in acquisition of features of lymphocyte [Term] id: GO:0030099 name: myeloid cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages." [GOC:add, ISBN:0781735149] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000763 ! results in acquisition of features of myeloid cell relationship: BFO:0000050 GO:0030097 ! part of hemopoiesis relationship: RO:0002315 CL:0000763 ! results in acquisition of features of myeloid cell [Term] id: GO:0030100 name: regulation of endocytosis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of endocytosis." [GOC:go_curators] is_a: GO:0051128 ! regulation of cellular component organization is_a: GO:0060627 ! regulation of vesicle-mediated transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006897 ! regulates (processual) endocytosis relationship: RO:0002211 GO:0006897 ! regulates (processual) endocytosis [Term] id: GO:0030133 name: transport vesicle namespace: cellular_component def: "Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell." [GOC:mah, PMID:22160157] synonym: "constitutive secretory pathway transport vesicle" EXACT [] xref: NIF_Subcellular:sao885490876 is_a: GO:0031410 ! cytoplasmic vesicle relationship: BFO:0000050 GO:0012505 ! part of endomembrane system [Term] id: GO:0030141 name: secretory granule namespace: cellular_component def: "A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules." [GOC:mah, ISBN:0198506732] is_a: GO:0099503 ! secretory vesicle relationship: BFO:0000050 GO:0012505 ! part of endomembrane system [Term] id: GO:0030154 name: cell differentiation namespace: biological_process def: "The cellular developmental process in which a relatively unspecialized cell, e.g. embryonic or regenerative cell, acquires specialized structural and/or functional features that characterize a specific cell. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state." [ISBN:0198506732] xref: Wikipedia:Cellular_differentiation is_a: GO:0048869 ! cellular developmental process intersection_of: GO:0048869 ! cellular developmental process intersection_of: RO:0002315 CL:0000000 ! results in acquisition of features of cell relationship: RO:0002315 CL:0000000 ! results in acquisition of features of cell [Term] id: GO:0030155 name: regulation of cell adhesion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix." [GOC:mah] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007155 ! regulates (processual) cell adhesion relationship: RO:0002211 GO:0007155 ! regulates (processual) cell adhesion [Term] id: GO:0030163 name: protein catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds." [GOC:mah] synonym: "cellular protein breakdown" EXACT [] synonym: "cellular protein catabolic process" EXACT [] synonym: "cellular protein catabolism" EXACT [] synonym: "cellular protein degradation" EXACT [] synonym: "protein breakdown" EXACT [] synonym: "protein catabolism" EXACT [] synonym: "protein degradation" EXACT [] xref: Wikipedia:Protein_catabolism is_a: GO:0019538 ! protein metabolic process is_a: GO:1901565 ! organonitrogen compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 PR:000000001 ! has primary input protein relationship: RO:0004009 PR:000000001 ! has primary input protein [Term] id: GO:0030182 name: neuron differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a neuron." [GOC:mah] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000540 ! results in acquisition of features of neuron relationship: BFO:0000050 GO:0048699 ! part of generation of neurons relationship: RO:0002315 CL:0000540 ! results in acquisition of features of neuron [Term] id: GO:0030198 name: extracellular matrix organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix." [GOC:mah] synonym: "extracellular matrix organisation" EXACT [] is_a: GO:0043062 ! extracellular structure organization is_a: GO:0045229 ! external encapsulating structure organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0031012 ! results in organization of extracellular matrix relationship: RO:0002592 GO:0031012 ! results in organization of extracellular matrix [Term] id: GO:0030199 name: collagen fibril organization namespace: biological_process def: "Any process that determines the size and arrangement of collagen fibrils within an extracellular matrix." [GOC:mah, ISBN:0815316194] synonym: "collagen fibril organisation" EXACT [] synonym: "fibrillar collagen organization" EXACT [GOC:mah] is_a: GO:0030198 ! extracellular matrix organization is_a: GO:0097435 ! supramolecular fiber organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0098643 ! results in organization of banded collagen fibril relationship: RO:0002592 GO:0098643 ! results in organization of banded collagen fibril [Term] id: GO:0030203 name: glycosaminoglycan metabolic process namespace: biological_process def: "The chemical reactions and pathways involving glycosaminoglycans, any of a group of polysaccharides that contain amino sugars." [ISBN:0192800981] synonym: "glycosaminoglycan metabolism" EXACT [] is_a: GO:0006022 ! aminoglycan metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:18085 ! has primary input or output glycosaminoglycan relationship: RO:0004007 CHEBI:18085 ! has primary input or output glycosaminoglycan [Term] id: GO:0030212 name: hyaluronan metabolic process namespace: biological_process def: "The chemical reactions and pathways involving hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine." [GOC:mah, ISBN:0198506732] synonym: "hyaluronan metabolism" EXACT [] is_a: GO:1903510 ! mucopolysaccharide metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:16336 ! has primary input or output hyaluronic acid relationship: RO:0004007 CHEBI:16336 ! has primary input or output hyaluronic acid [Term] id: GO:0030213 name: hyaluronan biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine." [GOC:mah, ISBN:0198506732] synonym: "hyaluronan anabolism" EXACT [] synonym: "hyaluronan biosynthesis" EXACT [] synonym: "hyaluronan formation" EXACT [] synonym: "hyaluronan synthesis" EXACT [] is_a: GO:0006024 ! glycosaminoglycan biosynthetic process is_a: GO:0030212 ! hyaluronan metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:16336 ! has primary output hyaluronic acid relationship: RO:0004008 CHEBI:16336 ! has primary output hyaluronic acid [Term] id: GO:0030214 name: hyaluronan catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine." [GOC:mah, ISBN:0198506732] synonym: "hyaluronan breakdown" EXACT [] synonym: "hyaluronan catabolism" EXACT [] synonym: "hyaluronan degradation" EXACT [] is_a: GO:0006027 ! glycosaminoglycan catabolic process is_a: GO:0030212 ! hyaluronan metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:16336 ! has primary input hyaluronic acid relationship: RO:0004009 CHEBI:16336 ! has primary input hyaluronic acid [Term] id: GO:0030217 name: T cell differentiation namespace: biological_process def: "The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex." [GO_REF:0000022, GOC:jid, GOC:mah] synonym: "T lymphocyte differentiation" EXACT [] synonym: "T-cell differentiation" EXACT [] synonym: "T-lymphocyte differentiation" EXACT [] is_a: GO:0030098 ! lymphocyte differentiation is_a: GO:0042110 ! T cell activation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000084 ! results in acquisition of features of T cell relationship: RO:0002315 CL:0000084 ! results in acquisition of features of T cell [Term] id: GO:0030218 name: erythrocyte differentiation namespace: biological_process def: "The process in which a myeloid precursor cell acquires specializes features of an erythrocyte." [GOC:mah] synonym: "erythrocyte cell differentiation" EXACT [] synonym: "erythropoiesis" EXACT [GOC:add, GOC:dph] synonym: "RBC differentiation" EXACT [CL:0000232] synonym: "red blood cell differentiation" EXACT [CL:0000232] xref: Wikipedia:Erythropoiesis is_a: GO:0030099 ! myeloid cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000232 ! results in acquisition of features of erythrocyte relationship: BFO:0000050 GO:0034101 ! part of erythrocyte homeostasis relationship: RO:0002315 CL:0000232 ! results in acquisition of features of erythrocyte [Term] id: GO:0030219 name: megakaryocyte differentiation namespace: biological_process def: "The process in which a myeloid precursor cell acquires specializes features of a megakaryocyte." [GOC:mah] synonym: "megakaryocyte cell differentiation" EXACT [] is_a: GO:0030099 ! myeloid cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000556 ! results in acquisition of features of megakaryocyte relationship: RO:0002315 CL:0000556 ! results in acquisition of features of megakaryocyte [Term] id: GO:0030239 name: myofibril assembly namespace: biological_process def: "Formation of myofibrils, the repeating units of striated muscle." [GOC:mah] is_a: GO:0010927 ! cellular component assembly involved in morphogenesis is_a: GO:0031032 ! actomyosin structure organization is_a: GO:0097435 ! supramolecular fiber organization is_a: GO:0140694 ! non-membrane-bounded organelle assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0030016 ! results in assembly of myofibril relationship: BFO:0000050 GO:0055002 ! part of striated muscle cell development relationship: RO:0002588 GO:0030016 ! results in assembly of myofibril [Term] id: GO:0030261 name: chromosome condensation namespace: biological_process def: "The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells." [GOC:mah, ISBN:0815316194] synonym: "eukaryotic chromosome condensation" EXACT [GOC:bf] synonym: "nuclear chromosome condensation" EXACT [GOC:bf] is_a: GO:0051276 ! chromosome organization [Term] id: GO:0030262 name: apoptotic nuclear changes namespace: biological_process def: "Alterations undergone by nuclei at the molecular and morphological level as part of the execution phase of apoptosis." [GOC:mah, GOC:mtg_apoptosis] is_a: GO:0006921 ! cellular component disassembly involved in execution phase of apoptosis [Term] id: GO:0030263 name: apoptotic chromosome condensation namespace: biological_process def: "The compaction of chromatin during apoptosis." [GOC:mah] synonym: "pyknosis" EXACT [] xref: Wikipedia:Pyknosis is_a: GO:0030261 ! chromosome condensation relationship: BFO:0000050 GO:0030262 ! part of apoptotic nuclear changes [Term] id: GO:0030264 name: nuclear fragmentation involved in apoptotic nuclear change namespace: biological_process def: "The breakdown of the nucleus into small membrane-bounded compartments, or blebs, each of which contain compacted DNA." [GOC:dph, GOC:mah, GOC:mtg_apoptosis, GOC:tb, ISBN:0721639976] synonym: "apoptotic nuclear fragmentation" EXACT [] synonym: "nucleus fragmentation" EXACT [] is_a: GO:0071763 ! nuclear membrane organization intersection_of: GO:0071763 ! nuclear membrane organization intersection_of: BFO:0000050 GO:0030262 ! part of apoptotic nuclear changes relationship: BFO:0000050 GO:0030262 ! part of apoptotic nuclear changes [Term] id: GO:0030278 name: regulation of ossification namespace: biological_process def: "Any process that modulates the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance." [GOC:go_curators] synonym: "regulation of bone biosynthesis" EXACT [] synonym: "regulation of bone formation" EXACT [] is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001503 ! regulates (processual) ossification relationship: RO:0002211 GO:0001503 ! regulates (processual) ossification [Term] id: GO:0030279 name: negative regulation of ossification namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance." [GOC:go_curators] synonym: "down regulation of ossification" EXACT [] synonym: "down-regulation of ossification" EXACT [] synonym: "downregulation of ossification" EXACT [] synonym: "negative regulation of bone biosynthesis" EXACT [] synonym: "negative regulation of bone formation" EXACT [] is_a: GO:0030278 ! regulation of ossification is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001503 ! negatively regulates ossification relationship: RO:0002212 GO:0001503 ! negatively regulates ossification [Term] id: GO:0030307 name: positive regulation of cell growth namespace: biological_process def: "Any process that activates or increases the frequency, rate, extent or direction of cell growth." [GOC:go_curators] synonym: "up regulation of cell growth" EXACT [] synonym: "up-regulation of cell growth" EXACT [] synonym: "upregulation of cell growth" EXACT [] is_a: GO:0001558 ! regulation of cell growth is_a: GO:0045927 ! positive regulation of growth is_a: GO:0048522 ! positive regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0016049 ! positively regulates cell growth relationship: RO:0002213 GO:0016049 ! positively regulates cell growth [Term] id: GO:0030308 name: negative regulation of cell growth namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth." [GOC:go_curators] synonym: "down regulation of cell growth" EXACT [] synonym: "down-regulation of cell growth" EXACT [] synonym: "downregulation of cell growth" EXACT [] is_a: GO:0001558 ! regulation of cell growth is_a: GO:0045926 ! negative regulation of growth is_a: GO:0048523 ! negative regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0016049 ! negatively regulates cell growth relationship: RO:0002212 GO:0016049 ! negatively regulates cell growth [Term] id: GO:0030312 name: external encapsulating structure namespace: cellular_component def: "A structure that lies outside the plasma membrane and surrounds the entire cell or cells. This does not include the periplasmic space." [GOC:go_curators] is_a: GO:0110165 ! cellular anatomical entity relationship: BFO:0000050 CL:0000000 ! part of cell relationship: BFO:0000050 GO:0071944 ! part of cell periphery [Term] id: GO:0030317 name: flagellated sperm motility namespace: biological_process def: "The directed, self-propelled movement of a cilium (aka flagellum) that contributes to the movement of a flagellated sperm." [GO_REF:0000060, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:26680031] synonym: "flagellated sperm movement" EXACT [] synonym: "sperm flagellum movement" EXACT [GOC:cilia, GOC:krc] synonym: "sperm flagellum movement involved in flagellated sperm motility" EXACT [] synonym: "sperm flagellum movement involved in flagellated sperm movement" EXACT [GOC:TermGenie] xref: Wikipedia:Sperm_motility is_a: GO:0060285 ! cilium-dependent cell motility is_a: GO:0060294 ! cilium movement involved in cell motility is_a: GO:0097722 ! sperm motility intersection_of: GO:0060285 ! cilium-dependent cell motility intersection_of: RO:0002565 CL:0000019 ! results in movement of sperm [Term] id: GO:0030323 name: respiratory tube development namespace: biological_process def: "The process whose specific outcome is the progression of the respiratory tube over time, from its formation to the mature structure. The respiratory tube is assumed to mean any tube in the respiratory tract." [GOC:jid] is_a: GO:0035295 ! tube development is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000117 ! results in development of respiratory tube relationship: RO:0002296 UBERON:0000117 ! results in development of respiratory tube [Term] id: GO:0030324 name: lung development namespace: biological_process def: "The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax." [GOC:jid, UBERON:0002048] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002048 ! results in development of lung relationship: BFO:0000050 GO:0030323 ! part of respiratory tube development relationship: BFO:0000050 GO:0060541 ! part of respiratory system development relationship: RO:0002296 UBERON:0002048 ! results in development of lung [Term] id: GO:0030334 name: regulation of cell migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell migration." [GOC:go_curators] is_a: GO:2000145 ! regulation of cell motility intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0016477 ! regulates (processual) cell migration relationship: RO:0002211 GO:0016477 ! regulates (processual) cell migration [Term] id: GO:0030335 name: positive regulation of cell migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell migration." [GOC:go_curators] synonym: "up regulation of cell migration" EXACT [] synonym: "up-regulation of cell migration" EXACT [] synonym: "upregulation of cell migration" EXACT [] is_a: GO:0030334 ! regulation of cell migration is_a: GO:2000147 ! positive regulation of cell motility intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0016477 ! positively regulates cell migration relationship: RO:0002213 GO:0016477 ! positively regulates cell migration [Term] id: GO:0030336 name: negative regulation of cell migration namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration." [GOC:go_curators] synonym: "down regulation of cell migration" EXACT [] synonym: "down-regulation of cell migration" EXACT [] synonym: "downregulation of cell migration" EXACT [] is_a: GO:0030334 ! regulation of cell migration is_a: GO:2000146 ! negative regulation of cell motility intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0016477 ! negatively regulates cell migration relationship: RO:0002212 GO:0016477 ! negatively regulates cell migration [Term] id: GO:0030397 name: membrane disassembly namespace: biological_process def: "The controlled breakdown of any cell membrane in the context of a normal process such as autophagy." [GOC:mah] synonym: "membrane breakdown" EXACT [] synonym: "membrane catabolism" EXACT [] synonym: "membrane degradation" EXACT [] is_a: GO:0022411 ! cellular component disassembly is_a: GO:0061024 ! membrane organization intersection_of: GO:0022411 ! cellular component disassembly intersection_of: RO:0002590 GO:0016020 ! results in disassembly of membrane relationship: RO:0002590 GO:0016020 ! results in disassembly of membrane [Term] id: GO:0030421 name: defecation namespace: biological_process def: "The expulsion of feces from the rectum." [GOC:mah] xref: Wikipedia:Defecation is_a: GO:0007588 ! excretion is_a: GO:0022600 ! digestive system process [Term] id: GO:0030432 name: peristalsis namespace: biological_process def: "A wavelike sequence of involuntary muscular contraction and relaxation that passes along a tubelike structure, such as the intestine, impelling the contents onwards." [ISBN:0198506732] xref: Wikipedia:Peristalsis is_a: GO:0014821 ! phasic smooth muscle contraction [Term] id: GO:0030473 name: nuclear migration along microtubule namespace: biological_process def: "The directed movement of the nucleus along microtubules within the cell, mediated by motor proteins." [GOC:mah, GOC:sgd_curators] synonym: "microtubule cytoskeleton-dependent nuclear positioning" EXACT [] synonym: "microtubule cytoskeleton-dependent nucleus positioning" EXACT [] synonym: "microtubule-dependent nuclear positioning" EXACT [] synonym: "microtubule-dependent nucleus positioning" EXACT [] synonym: "microtubule-mediated nuclear migration" EXACT [] synonym: "nuclear migration, microtubule-mediated" EXACT [] synonym: "transport of nucleus by microtubules" EXACT [] synonym: "transport of nucleus, microtubule-mediated" EXACT [] is_a: GO:0007097 ! nuclear migration is_a: GO:0072384 ! organelle transport along microtubule intersection_of: GO:0007097 ! nuclear migration intersection_of: RO:0002341 GO:0015630 ! results in transport along microtubule cytoskeleton relationship: RO:0002341 GO:0015630 ! results in transport along microtubule cytoskeleton [Term] id: GO:0030485 name: smooth muscle contractile fiber namespace: cellular_component def: "The contractile fiber of smooth muscle cells." [GOC:mah] is_a: GO:0043292 ! contractile fiber intersection_of: GO:0043292 ! contractile fiber intersection_of: BFO:0000050 CL:0000192 ! part of smooth muscle cell relationship: BFO:0000050 CL:0000192 ! part of smooth muscle cell [Term] id: GO:0030539 name: male genitalia development namespace: biological_process def: "The process whose specific outcome is the progression of the male genitalia over time, from its formation to the mature structure." [GOC:ems, ISBN:0140512888] synonym: "male genital development" EXACT [] is_a: GO:0048806 ! genitalia development is_a: GO:0061458 ! reproductive system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000079 ! results in development of male reproductive system relationship: BFO:0000050 GO:0046661 ! part of male sex differentiation relationship: RO:0002296 UBERON:0000079 ! results in development of male reproductive system [Term] id: GO:0030573 name: bile acid catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of bile acids, any of a group of steroid carboxylic acids occurring in bile." [GOC:go_curators] synonym: "bile acid breakdown" EXACT [] synonym: "bile acid catabolism" EXACT [] synonym: "bile acid degradation" EXACT [] is_a: GO:0008206 ! bile acid metabolic process is_a: GO:0072329 ! monocarboxylic acid catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:36235 ! has primary input bile acid anion relationship: RO:0004009 CHEBI:36235 ! has primary input bile acid anion [Term] id: GO:0030574 name: collagen catabolic process namespace: biological_process def: "The proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix, usually carried out by proteases secreted by nearby cells." [GOC:mah, ISBN:0815316194] synonym: "collagen breakdown" EXACT [] synonym: "collagen catabolism" EXACT [] synonym: "collagen degradation" EXACT [] is_a: GO:0009056 ! catabolic process is_a: GO:0032963 ! collagen metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 GO:0005581 ! has primary input collagen trimer relationship: RO:0004009 GO:0005581 ! has primary input collagen trimer [Term] id: GO:0030658 name: transport vesicle membrane namespace: cellular_component def: "The lipid bilayer surrounding a transport vesicle." [GOC:mah] synonym: "constitutive secretory pathway transport vesicle membrane" EXACT [] is_a: GO:0030659 ! cytoplasmic vesicle membrane is_a: GO:0098588 ! bounding membrane of organelle intersection_of: GO:0016020 ! membrane intersection_of: RO:0002007 GO:0030133 ! bounding layer of transport vesicle relationship: RO:0002007 GO:0030133 ! bounding layer of transport vesicle [Term] id: GO:0030659 name: cytoplasmic vesicle membrane namespace: cellular_component def: "The lipid bilayer surrounding a cytoplasmic vesicle." [GOC:mah] is_a: GO:0012506 ! vesicle membrane intersection_of: GO:0016020 ! membrane intersection_of: BFO:0000050 GO:0031410 ! part of cytoplasmic vesicle relationship: BFO:0000050 GO:0031410 ! part of cytoplasmic vesicle [Term] id: GO:0030660 name: Golgi-associated vesicle membrane namespace: cellular_component def: "The lipid bilayer surrounding a vesicle associated with the Golgi apparatus." [GOC:mah] is_a: GO:0030659 ! cytoplasmic vesicle membrane is_a: GO:0098588 ! bounding membrane of organelle intersection_of: GO:0016020 ! membrane intersection_of: RO:0002007 GO:0005798 ! bounding layer of Golgi-associated vesicle relationship: RO:0002007 GO:0005798 ! bounding layer of Golgi-associated vesicle [Term] id: GO:0030667 name: secretory granule membrane namespace: cellular_component def: "The lipid bilayer surrounding a secretory granule." [GOC:mah] is_a: GO:0030659 ! cytoplasmic vesicle membrane is_a: GO:0098588 ! bounding membrane of organelle intersection_of: GO:0016020 ! membrane intersection_of: RO:0002007 GO:0030141 ! bounding layer of secretory granule relationship: RO:0002007 GO:0030141 ! bounding layer of secretory granule [Term] id: GO:0030705 name: cytoskeleton-dependent intracellular transport namespace: biological_process def: "The directed movement of substances along cytoskeletal fibers such as microfilaments or microtubules within a cell." [GOC:mah] is_a: GO:0046907 ! intracellular transport intersection_of: GO:0046907 ! intracellular transport intersection_of: RO:0002341 GO:0099513 ! results in transport along polymeric cytoskeletal fiber relationship: RO:0002341 GO:0099513 ! results in transport along polymeric cytoskeletal fiber [Term] id: GO:0030718 name: germ-line stem cell population maintenance namespace: biological_process def: "Any process by which an organism or tissue maintains a population of germ-line stem cells." [ISBN:0879694238] is_a: GO:0019827 ! stem cell population maintenance intersection_of: GO:0098727 ! maintenance of cell number intersection_of: RO:0012003 CL:0000014 ! acts on population of germ line stem cell relationship: RO:0012003 CL:0000014 ! acts on population of germ line stem cell [Term] id: GO:0030720 name: oocyte localization involved in germarium-derived egg chamber formation namespace: biological_process def: "Directed movement of the oocyte, following its specification, from its original central position in the cyst to a posterior position relative to the nurse cells of the egg chamber, and its maintenance in this posterior location. This is the first sign of anterior-posterior asymmetry in the developing egg chamber." [GOC:mtg_sensu, PMID:10449356] synonym: "establishment and maintenance of oocyte localization in egg chamber" EXACT [] synonym: "establishment and maintenance of oocyte position during oogenesis" EXACT [] synonym: "oocyte localisation involved in germarium-derived egg chamber formation" EXACT [GOC:mah] synonym: "oogenesis, establishment and maintenance of oocyte localization" EXACT [] synonym: "oogenesis, oocyte localization" EXACT [] is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0051674 ! localization of cell intersection_of: GO:0051179 ! localization intersection_of: RO:0004009 CL:0000023 ! has primary input oocyte relationship: BFO:0000050 GO:0007293 ! part of germarium-derived egg chamber formation relationship: RO:0002160 NCBITaxon:50557 ! only in taxon Insecta relationship: RO:0002162 NCBITaxon:50557 {all_only="true"} ! in taxon Insecta relationship: RO:0004009 CL:0000023 ! has primary input oocyte [Term] id: GO:0030855 name: epithelial cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium." [GOC:ecd, PMID:11839751] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000066 ! results in acquisition of features of epithelial cell relationship: BFO:0000050 GO:0060429 ! part of epithelium development relationship: RO:0002315 CL:0000066 ! results in acquisition of features of epithelial cell [Term] id: GO:0030856 name: regulation of epithelial cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of epithelial cell differentiation." [GOC:mah] is_a: GO:0045595 ! regulation of cell differentiation is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030855 ! regulates (processual) epithelial cell differentiation relationship: RO:0002211 GO:0030855 ! regulates (processual) epithelial cell differentiation [Term] id: GO:0030857 name: negative regulation of epithelial cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell differentiation." [GOC:mah] synonym: "down regulation of epithelial cell differentiation" EXACT [] synonym: "down-regulation of epithelial cell differentiation" EXACT [] synonym: "downregulation of epithelial cell differentiation" EXACT [] is_a: GO:0030856 ! regulation of epithelial cell differentiation is_a: GO:0045596 ! negative regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030855 ! negatively regulates epithelial cell differentiation relationship: RO:0002212 GO:0030855 ! negatively regulates epithelial cell differentiation [Term] id: GO:0030858 name: positive regulation of epithelial cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation." [GOC:mah] synonym: "up regulation of epithelial cell differentiation" EXACT [] synonym: "up-regulation of epithelial cell differentiation" EXACT [] synonym: "upregulation of epithelial cell differentiation" EXACT [] is_a: GO:0030856 ! regulation of epithelial cell differentiation is_a: GO:0045597 ! positive regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030855 ! positively regulates epithelial cell differentiation relationship: RO:0002213 GO:0030855 ! positively regulates epithelial cell differentiation [Term] id: GO:0030901 name: midbrain development namespace: biological_process def: "The process whose specific outcome is the progression of the midbrain over time, from its formation to the mature structure. The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles)." [http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=midbrain] synonym: "mesencephalon development" EXACT [] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001891 ! results in development of midbrain relationship: BFO:0000050 GO:0007420 ! part of brain development relationship: RO:0002296 UBERON:0001891 ! results in development of midbrain [Term] id: GO:0030902 name: hindbrain development namespace: biological_process def: "The process whose specific outcome is the progression of the hindbrain over time, from its formation to the mature structure. The hindbrain is the posterior of the three primary divisions of the developing chordate brain, or the corresponding part of the adult brain (in vertebrates, includes the cerebellum, pons, and medulla oblongata and controls the autonomic functions and equilibrium)." [http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=hindbrain] synonym: "rhombencephalon development" EXACT [] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002028 ! results in development of hindbrain relationship: BFO:0000050 GO:0007420 ! part of brain development relationship: RO:0002296 UBERON:0002028 ! results in development of hindbrain [Term] id: GO:0030903 name: notochord development namespace: biological_process def: "The process whose specific outcome is the progression of the notochord over time, from its formation to the mature structure. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column." [GOC:dgh] is_a: GO:0048568 ! embryonic organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002328 ! results in development of notochord relationship: RO:0002296 UBERON:0002328 ! results in development of notochord [Term] id: GO:0030917 name: midbrain-hindbrain boundary development namespace: biological_process def: "The process whose specific outcome is the progression of the midbrain-hindbrain boundary over time, from its formation to the mature structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages." [GOC:dgh] synonym: "isthmic organizer development" EXACT [] synonym: "isthmomesencephalic boundary development" EXACT [] synonym: "isthmus development" EXACT [] synonym: "MHB development" EXACT [] synonym: "midbrain-hindbrain orgainizer development" EXACT [] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003052 ! results in development of midbrain-hindbrain boundary relationship: BFO:0000050 GO:0007420 ! part of brain development relationship: BFO:0000050 GO:0021903 ! part of rostrocaudal neural tube patterning relationship: RO:0002296 UBERON:0003052 ! results in development of midbrain-hindbrain boundary [Term] id: GO:0030936 name: transmembrane collagen trimer namespace: cellular_component def: "Any collagen trimer that passes through a lipid bilayer membrane." [ISBN:0721639976] synonym: "MACIT" EXACT [ISBN:0198599587] is_a: GO:0005581 ! collagen trimer is_a: GO:0098797 ! plasma membrane protein complex intersection_of: GO:0005581 ! collagen trimer intersection_of: BFO:0000050 GO:0005886 ! part of plasma membrane [Term] id: GO:0030951 name: establishment or maintenance of microtubule cytoskeleton polarity namespace: biological_process def: "Any cellular process that results in the specification, formation or maintenance of polarized microtubule-based cytoskeletal structures." [GOC:mah] is_a: GO:0000226 ! microtubule cytoskeleton organization is_a: GO:0030952 ! establishment or maintenance of cytoskeleton polarity [Term] id: GO:0030952 name: establishment or maintenance of cytoskeleton polarity namespace: biological_process def: "Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures." [GOC:mah] is_a: GO:0007010 ! cytoskeleton organization is_a: GO:0007163 ! establishment or maintenance of cell polarity [Term] id: GO:0030990 name: intraciliary transport particle namespace: cellular_component def: "A nonmembrane-bound oligomeric protein complex that participates in bidirectional transport of molecules (cargo) along axonemal microtubules." [GOC:cilia, GOC:kmv, PMID:14570576, PMID:22118932, PMID:23945166] synonym: "intraflagellar transport complex" EXACT [] synonym: "intraflagellar transport particle" EXACT [] is_a: GO:0032991 ! protein-containing complex relationship: RO:0002216 GO:0035735 ! capable of part of intraciliary transport involved in cilium assembly [Term] id: GO:0031012 name: extracellular matrix namespace: cellular_component def: "A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues." [GOC:BHF, GOC:mah, GOC:rph, NIF_Subcellular:nlx_subcell_20090513, PMID:21123617, PMID:28089324] synonym: "proteinaceous extracellular matrix" EXACT [] xref: NIF_Subcellular:nlx_subcell_20090513 xref: Wikipedia:Extracellular_matrix is_a: GO:0030312 ! external encapsulating structure disjoint_from: GO:0032991 ! protein-containing complex disjoint_from: GO:0043226 ! organelle [Term] id: GO:0031016 name: pancreas development namespace: biological_process def: "The process whose specific outcome is the progression of the pancreas over time, from its formation to the mature structure. The pancreas is an endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating hormones." [GOC:cvs] xref: Wikipedia:Pancreas is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001264 ! results in development of pancreas relationship: RO:0002296 UBERON:0001264 ! results in development of pancreas [Term] id: GO:0031017 name: exocrine pancreas development namespace: biological_process def: "The process whose specific outcome is the progression of the exocrine pancreas over time, from its formation to the mature structure. The exocrine pancreas produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells." [GOC:cvs] is_a: GO:0048732 ! gland development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000017 ! results in development of exocrine pancreas relationship: BFO:0000050 GO:0031016 ! part of pancreas development relationship: BFO:0000050 GO:0035272 ! part of exocrine system development relationship: BFO:0000050 GO:0055123 ! part of digestive system development relationship: RO:0002296 UBERON:0000017 ! results in development of exocrine pancreas [Term] id: GO:0031018 name: endocrine pancreas development namespace: biological_process def: "The process whose specific outcome is the progression of the endocrine pancreas over time, from its formation to the mature structure. The endocrine pancreas is made up of islet cells that produce insulin, glucagon and somatostatin." [GOC:cvs] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000016 ! results in development of endocrine pancreas relationship: BFO:0000050 GO:0031016 ! part of pancreas development relationship: BFO:0000050 GO:0035270 ! part of endocrine system development relationship: RO:0002296 UBERON:0000016 ! results in development of endocrine pancreas [Term] id: GO:0031022 name: nuclear migration along microfilament namespace: biological_process def: "The directed movement of the nucleus along microfilaments within the cell, mediated by motor proteins." [GOC:mah] synonym: "nuclear migration, microfilament-mediated" EXACT [] is_a: GO:0007097 ! nuclear migration is_a: GO:0030048 ! actin filament-based movement is_a: GO:0099515 ! actin filament-based transport intersection_of: GO:0007097 ! nuclear migration intersection_of: RO:0002341 GO:0005884 ! results in transport along actin filament [Term] id: GO:0031032 name: actomyosin structure organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin. The myosin may be organized into filaments." [GOC:dph, GOC:jl, GOC:mah] synonym: "actomyosin organization" EXACT [] synonym: "actomyosin structure organisation" EXACT [] is_a: GO:0030036 ! actin cytoskeleton organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0042641 ! results in organization of actomyosin relationship: RO:0002592 GO:0042641 ! results in organization of actomyosin [Term] id: GO:0031045 name: dense core granule namespace: cellular_component def: "Electron-dense organelle with a granular internal matrix; contains proteins destined to be secreted." [NIF_Subcellular:sao772007592, PMID:14690495] xref: NIF_Subcellular:sao772007592 is_a: GO:0030141 ! secretory granule [Term] id: GO:0031076 name: embryonic camera-type eye development namespace: biological_process def: "The process occurring during the embryonic phase whose specific outcome is the progression of the eye over time, from its formation to the mature structure." [GOC:mah, GOC:mtg_sensu] synonym: "embryonic eye development" EXACT [] is_a: GO:0043010 ! camera-type eye development is_a: GO:0048568 ! embryonic organ development [Term] id: GO:0031090 name: organelle membrane namespace: cellular_component def: "A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle." [GOC:dos, GOC:mah] xref: NIF_Subcellular:sao830981606 is_a: GO:0016020 ! membrane intersection_of: GO:0016020 ! membrane intersection_of: BFO:0000050 GO:0043227 ! part of membrane-bounded organelle relationship: BFO:0000050 GO:0043227 ! part of membrane-bounded organelle [Term] id: GO:0031109 name: microtubule polymerization or depolymerization namespace: biological_process def: "Assembly or disassembly of microtubules by the addition or removal of tubulin heterodimers from a microtubule." [GOC:mah] synonym: "microtubule dynamics" EXACT [] is_a: GO:0000226 ! microtubule cytoskeleton organization [Term] id: GO:0031110 name: regulation of microtubule polymerization or depolymerization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of microtubule polymerization or depolymerization by the addition or removal of tubulin heterodimers from a microtubule." [GOC:mah] is_a: GO:0070507 ! regulation of microtubule cytoskeleton organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0031109 ! regulates (processual) microtubule polymerization or depolymerization relationship: RO:0002211 GO:0031109 ! regulates (processual) microtubule polymerization or depolymerization [Term] id: GO:0031111 name: negative regulation of microtubule polymerization or depolymerization namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization or depolymerization." [GOC:mah] synonym: "down regulation of microtubule polymerization or depolymerization" EXACT [] synonym: "down-regulation of microtubule polymerization or depolymerization" EXACT [] synonym: "downregulation of microtubule polymerization or depolymerization" EXACT [] is_a: GO:0031110 ! regulation of microtubule polymerization or depolymerization is_a: GO:0051494 ! negative regulation of cytoskeleton organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0031109 ! negatively regulates microtubule polymerization or depolymerization relationship: RO:0002212 GO:0031109 ! negatively regulates microtubule polymerization or depolymerization [Term] id: GO:0031112 name: positive regulation of microtubule polymerization or depolymerization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of microtubule polymerization or depolymerization." [GOC:mah] synonym: "up regulation of microtubule polymerization or depolymerization" EXACT [] synonym: "up-regulation of microtubule polymerization or depolymerization" EXACT [] synonym: "upregulation of microtubule polymerization or depolymerization" EXACT [] is_a: GO:0031110 ! regulation of microtubule polymerization or depolymerization is_a: GO:0051495 ! positive regulation of cytoskeleton organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0031109 ! positively regulates microtubule polymerization or depolymerization relationship: RO:0002213 GO:0031109 ! positively regulates microtubule polymerization or depolymerization [Term] id: GO:0031113 name: regulation of microtubule polymerization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of microtubule polymerization." [GOC:mah] is_a: GO:0031110 ! regulation of microtubule polymerization or depolymerization is_a: GO:0032271 ! regulation of protein polymerization is_a: GO:1902903 ! regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0046785 ! regulates (processual) microtubule polymerization relationship: RO:0002211 GO:0046785 ! regulates (processual) microtubule polymerization [Term] id: GO:0031114 name: regulation of microtubule depolymerization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of microtubule depolymerization." [GOC:mah] synonym: "regulation of microtubule disassembly" EXACT [] is_a: GO:0031110 ! regulation of microtubule polymerization or depolymerization is_a: GO:1901879 ! regulation of protein depolymerization is_a: GO:1902903 ! regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007019 ! regulates (processual) microtubule depolymerization relationship: RO:0002211 GO:0007019 ! regulates (processual) microtubule depolymerization [Term] id: GO:0031115 name: negative regulation of microtubule polymerization namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization." [GOC:mah] synonym: "down regulation of microtubule polymerization" EXACT [] synonym: "down-regulation of microtubule polymerization" EXACT [] synonym: "downregulation of microtubule polymerization" EXACT [] is_a: GO:0031111 ! negative regulation of microtubule polymerization or depolymerization is_a: GO:0031113 ! regulation of microtubule polymerization is_a: GO:0032272 ! negative regulation of protein polymerization is_a: GO:1902904 ! negative regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0046785 ! negatively regulates microtubule polymerization relationship: RO:0002212 GO:0046785 ! negatively regulates microtubule polymerization [Term] id: GO:0031116 name: positive regulation of microtubule polymerization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of microtubule polymerization." [GOC:mah] synonym: "up regulation of microtubule polymerization" EXACT [] synonym: "up-regulation of microtubule polymerization" EXACT [] synonym: "upregulation of microtubule polymerization" EXACT [] is_a: GO:0031112 ! positive regulation of microtubule polymerization or depolymerization is_a: GO:0031113 ! regulation of microtubule polymerization is_a: GO:0032273 ! positive regulation of protein polymerization is_a: GO:1902905 ! positive regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0046785 ! positively regulates microtubule polymerization relationship: RO:0002213 GO:0046785 ! positively regulates microtubule polymerization [Term] id: GO:0031117 name: positive regulation of microtubule depolymerization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of microtubule depolymerization." [GOC:mah] synonym: "microtubule destabilization" EXACT [] synonym: "positive regulation of microtubule disassembly" EXACT [] synonym: "up regulation of microtubule depolymerization" EXACT [] synonym: "up-regulation of microtubule depolymerization" EXACT [] synonym: "upregulation of microtubule depolymerization" EXACT [] is_a: GO:0031112 ! positive regulation of microtubule polymerization or depolymerization is_a: GO:0031114 ! regulation of microtubule depolymerization is_a: GO:1901881 ! positive regulation of protein depolymerization is_a: GO:1902905 ! positive regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007019 ! positively regulates microtubule depolymerization relationship: RO:0002213 GO:0007019 ! positively regulates microtubule depolymerization [Term] id: GO:0031122 name: cytoplasmic microtubule organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell." [GOC:mah] synonym: "cytoplasmic microtubule organisation" EXACT [] is_a: GO:0000226 ! microtubule cytoskeleton organization is_a: GO:0097435 ! supramolecular fiber organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0005881 ! results in organization of cytoplasmic microtubule relationship: RO:0002592 GO:0005881 ! results in organization of cytoplasmic microtubule [Term] id: GO:0031128 name: developmental induction namespace: biological_process def: "A developmental process involving two tissues in which one tissue (the inducer) produces a signal that directs cell fate commitment of cells in the second tissue (the responder)." [GOC:cjm, GOC:dph, GOC:mah, PMID:24503535] is_a: GO:0032502 ! developmental process intersection_of: GO:0032502 ! developmental process intersection_of: BFO:0000051 GO:0045168 ! has part cell-cell signaling involved in cell fate commitment relationship: BFO:0000051 GO:0045168 ! has part cell-cell signaling involved in cell fate commitment [Term] id: GO:0031175 name: neuron projection development namespace: biological_process def: "The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." [GOC:mah] is_a: GO:0120036 ! plasma membrane bounded cell projection organization intersection_of: GO:0120036 ! plasma membrane bounded cell projection organization intersection_of: BFO:0000050 GO:0048666 ! part of neuron development relationship: BFO:0000050 GO:0048666 ! part of neuron development [Term] id: GO:0031252 name: cell leading edge namespace: cellular_component def: "The area of a motile cell closest to the direction of movement." [GOC:pg] synonym: "front of cell" EXACT [] synonym: "leading edge of cell" EXACT [] is_a: GO:0110165 ! cellular anatomical entity relationship: BFO:0000050 CL:0000000 ! part of cell [Term] id: GO:0031253 name: cell projection membrane namespace: cellular_component def: "The portion of the plasma membrane surrounding a plasma membrane bounded cell surface projection." [GOC:krc, GOC:mah] is_a: GO:0098590 ! plasma membrane region intersection_of: GO:0016020 ! membrane intersection_of: RO:0002007 GO:0120025 ! bounding layer of plasma membrane bounded cell projection relationship: RO:0002007 GO:0120025 ! bounding layer of plasma membrane bounded cell projection [Term] id: GO:0031256 name: leading edge membrane namespace: cellular_component def: "The portion of the plasma membrane surrounding the leading edge of a motile cell." [GOC:mah] is_a: GO:0110165 ! cellular anatomical entity relationship: BFO:0000050 GO:0005886 ! part of plasma membrane relationship: BFO:0000050 GO:0031252 ! part of cell leading edge [Term] id: GO:0031323 name: regulation of cellular metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances." [GOC:mah] synonym: "regulation of cellular metabolism" EXACT [] is_a: GO:0019222 ! regulation of metabolic process is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0044237 ! regulates (processual) cellular metabolic process relationship: RO:0002211 GO:0044237 ! regulates (processual) cellular metabolic process [Term] id: GO:0031324 name: negative regulation of cellular metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances." [GOC:mah] synonym: "down regulation of cellular metabolic process" EXACT [] synonym: "down-regulation of cellular metabolic process" EXACT [] synonym: "downregulation of cellular metabolic process" EXACT [] synonym: "negative regulation of cellular metabolism" EXACT [] is_a: GO:0009892 ! negative regulation of metabolic process is_a: GO:0031323 ! regulation of cellular metabolic process is_a: GO:0048523 ! negative regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0044237 ! negatively regulates cellular metabolic process relationship: RO:0002212 GO:0044237 ! negatively regulates cellular metabolic process [Term] id: GO:0031325 name: positive regulation of cellular metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances." [GOC:mah] synonym: "positive regulation of cellular metabolism" EXACT [] synonym: "up regulation of cellular metabolic process" EXACT [] synonym: "up-regulation of cellular metabolic process" EXACT [] synonym: "upregulation of cellular metabolic process" EXACT [] is_a: GO:0009893 ! positive regulation of metabolic process is_a: GO:0031323 ! regulation of cellular metabolic process is_a: GO:0048522 ! positive regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0044237 ! positively regulates cellular metabolic process relationship: RO:0002213 GO:0044237 ! positively regulates cellular metabolic process [Term] id: GO:0031326 name: regulation of cellular biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." [GOC:mah] synonym: "regulation of cellular anabolism" EXACT [] synonym: "regulation of cellular biosynthesis" EXACT [] synonym: "regulation of cellular formation" EXACT [] synonym: "regulation of cellular synthesis" EXACT [] is_a: GO:0009889 ! regulation of biosynthetic process is_a: GO:0031323 ! regulation of cellular metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0044249 ! regulates (processual) cellular biosynthetic process relationship: RO:0002211 GO:0044249 ! regulates (processual) cellular biosynthetic process [Term] id: GO:0031327 name: negative regulation of cellular biosynthetic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." [GOC:mah] synonym: "down regulation of cellular biosynthetic process" EXACT [] synonym: "down-regulation of cellular biosynthetic process" EXACT [] synonym: "downregulation of cellular biosynthetic process" EXACT [] synonym: "negative regulation of cellular anabolism" EXACT [] synonym: "negative regulation of cellular biosynthesis" EXACT [] synonym: "negative regulation of cellular formation" EXACT [] synonym: "negative regulation of cellular synthesis" EXACT [] is_a: GO:0009890 ! negative regulation of biosynthetic process is_a: GO:0031324 ! negative regulation of cellular metabolic process is_a: GO:0031326 ! regulation of cellular biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0044249 ! negatively regulates cellular biosynthetic process relationship: RO:0002212 GO:0044249 ! negatively regulates cellular biosynthetic process [Term] id: GO:0031328 name: positive regulation of cellular biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." [GOC:mah] synonym: "positive regulation of cellular anabolism" EXACT [] synonym: "positive regulation of cellular biosynthesis" EXACT [] synonym: "positive regulation of cellular formation" EXACT [] synonym: "positive regulation of cellular synthesis" EXACT [] synonym: "up regulation of cellular biosynthetic process" EXACT [] synonym: "up-regulation of cellular biosynthetic process" EXACT [] synonym: "upregulation of cellular biosynthetic process" EXACT [] is_a: GO:0009891 ! positive regulation of biosynthetic process is_a: GO:0031325 ! positive regulation of cellular metabolic process is_a: GO:0031326 ! regulation of cellular biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0044249 ! positively regulates cellular biosynthetic process relationship: RO:0002213 GO:0044249 ! positively regulates cellular biosynthetic process [Term] id: GO:0031329 name: regulation of cellular catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells." [GOC:mah] synonym: "regulation of cellular breakdown" EXACT [] synonym: "regulation of cellular catabolism" EXACT [] synonym: "regulation of cellular degradation" EXACT [] is_a: GO:0009894 ! regulation of catabolic process is_a: GO:0031323 ! regulation of cellular metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0044248 ! regulates (processual) cellular catabolic process relationship: RO:0002211 GO:0044248 ! regulates (processual) cellular catabolic process [Term] id: GO:0031330 name: negative regulation of cellular catabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells." [GOC:mah] synonym: "down regulation of cellular catabolic process" EXACT [] synonym: "down-regulation of cellular catabolic process" EXACT [] synonym: "downregulation of cellular catabolic process" EXACT [] synonym: "negative regulation of cellular breakdown" EXACT [] synonym: "negative regulation of cellular catabolism" EXACT [] synonym: "negative regulation of cellular degradation" EXACT [] is_a: GO:0009895 ! negative regulation of catabolic process is_a: GO:0031324 ! negative regulation of cellular metabolic process is_a: GO:0031329 ! regulation of cellular catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0044248 ! negatively regulates cellular catabolic process relationship: RO:0002212 GO:0044248 ! negatively regulates cellular catabolic process [Term] id: GO:0031331 name: positive regulation of cellular catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells." [GOC:mah] synonym: "positive regulation of cellular breakdown" EXACT [] synonym: "positive regulation of cellular catabolism" EXACT [] synonym: "positive regulation of cellular degradation" EXACT [] synonym: "up regulation of cellular catabolic process" EXACT [] synonym: "up-regulation of cellular catabolic process" EXACT [] synonym: "upregulation of cellular catabolic process" EXACT [] is_a: GO:0009896 ! positive regulation of catabolic process is_a: GO:0031325 ! positive regulation of cellular metabolic process is_a: GO:0031329 ! regulation of cellular catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0044248 ! positively regulates cellular catabolic process relationship: RO:0002213 GO:0044248 ! positively regulates cellular catabolic process [Term] id: GO:0031333 name: negative regulation of protein-containing complex assembly namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly." [GOC:mah] synonym: "down regulation of protein complex assembly" EXACT [] synonym: "down-regulation of protein complex assembly" EXACT [] synonym: "downregulation of protein complex assembly" EXACT [] is_a: GO:0043254 ! regulation of protein-containing complex assembly is_a: GO:0051129 ! negative regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0065003 ! negatively regulates protein-containing complex assembly relationship: RO:0002212 GO:0065003 ! negatively regulates protein-containing complex assembly [Term] id: GO:0031334 name: positive regulation of protein-containing complex assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein complex assembly." [GOC:mah] synonym: "up regulation of protein complex assembly" EXACT [] synonym: "up-regulation of protein complex assembly" EXACT [] synonym: "upregulation of protein complex assembly" EXACT [] is_a: GO:0043254 ! regulation of protein-containing complex assembly is_a: GO:0044089 ! positive regulation of cellular component biogenesis is_a: GO:0051130 ! positive regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0065003 ! positively regulates protein-containing complex assembly relationship: RO:0002213 GO:0065003 ! positively regulates protein-containing complex assembly [Term] id: GO:0031338 name: regulation of vesicle fusion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of vesicle fusion." [GOC:mah] is_a: GO:0033043 ! regulation of organelle organization is_a: GO:0060627 ! regulation of vesicle-mediated transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006906 ! regulates (processual) vesicle fusion relationship: RO:0002211 GO:0006906 ! regulates (processual) vesicle fusion [Term] id: GO:0031339 name: negative regulation of vesicle fusion namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of vesicle fusion." [GOC:mah] synonym: "down regulation of vesicle fusion" EXACT [] synonym: "down-regulation of vesicle fusion" EXACT [] synonym: "downregulation of vesicle fusion" EXACT [] is_a: GO:0010639 ! negative regulation of organelle organization is_a: GO:0031338 ! regulation of vesicle fusion is_a: GO:0051051 ! negative regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006906 ! negatively regulates vesicle fusion relationship: RO:0002212 GO:0006906 ! negatively regulates vesicle fusion [Term] id: GO:0031340 name: positive regulation of vesicle fusion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of vesicle fusion." [GOC:mah] synonym: "up regulation of vesicle fusion" EXACT [] synonym: "up-regulation of vesicle fusion" EXACT [] synonym: "upregulation of vesicle fusion" EXACT [] is_a: GO:0010638 ! positive regulation of organelle organization is_a: GO:0031338 ! regulation of vesicle fusion is_a: GO:0051050 ! positive regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006906 ! positively regulates vesicle fusion relationship: RO:0002213 GO:0006906 ! positively regulates vesicle fusion [Term] id: GO:0031344 name: regulation of cell projection organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections." [GOC:mah] synonym: "regulation of cell projection organisation" EXACT [] is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030030 ! regulates (processual) cell projection organization relationship: RO:0002211 GO:0030030 ! regulates (processual) cell projection organization [Term] id: GO:0031345 name: negative regulation of cell projection organization namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections." [GOC:mah] synonym: "down regulation of cell projection organization" EXACT [GOC:mah] synonym: "down-regulation of cell projection organization" EXACT [] synonym: "downregulation of cell projection organization" EXACT [] synonym: "negative regulation of cell projection organisation" EXACT [] is_a: GO:0031344 ! regulation of cell projection organization is_a: GO:0051129 ! negative regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030030 ! negatively regulates cell projection organization relationship: RO:0002212 GO:0030030 ! negatively regulates cell projection organization [Term] id: GO:0031346 name: positive regulation of cell projection organization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the process involved in the formation, arrangement of constituent parts, or disassembly of cell projections." [GOC:mah] synonym: "positive regulation of cell projection organisation" EXACT [] synonym: "up regulation of cell projection organization" EXACT [] synonym: "up-regulation of cell projection organization" EXACT [] synonym: "upregulation of cell projection organization" EXACT [] is_a: GO:0031344 ! regulation of cell projection organization is_a: GO:0051130 ! positive regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030030 ! positively regulates cell projection organization relationship: RO:0002213 GO:0030030 ! positively regulates cell projection organization [Term] id: GO:0031347 name: regulation of defense response namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a defense response." [GOC:mah] is_a: GO:0080134 ! regulation of response to stress intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006952 ! regulates (processual) defense response relationship: RO:0002211 GO:0006952 ! regulates (processual) defense response [Term] id: GO:0031348 name: negative regulation of defense response namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response." [GOC:mah] synonym: "down regulation of defense response" EXACT [] synonym: "down-regulation of defense response" EXACT [] synonym: "downregulation of defense response" EXACT [] is_a: GO:0031347 ! regulation of defense response is_a: GO:0048585 ! negative regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006952 ! negatively regulates defense response relationship: RO:0002212 GO:0006952 ! negatively regulates defense response [Term] id: GO:0031349 name: positive regulation of defense response namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of a defense response." [GOC:mah] synonym: "up regulation of defense response" EXACT [] synonym: "up-regulation of defense response" EXACT [] synonym: "upregulation of defense response" EXACT [] is_a: GO:0031347 ! regulation of defense response is_a: GO:0048584 ! positive regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006952 ! positively regulates defense response relationship: RO:0002213 GO:0006952 ! positively regulates defense response [Term] id: GO:0031410 name: cytoplasmic vesicle namespace: cellular_component def: "A vesicle found in the cytoplasm of a cell." [GOC:ai, GOC:mah, GOC:vesicles] xref: NIF_Subcellular:sao180601769 is_a: GO:0097708 ! intracellular vesicle intersection_of: GO:0031982 ! vesicle intersection_of: BFO:0000050 GO:0005737 ! part of cytoplasm relationship: BFO:0000050 GO:0005737 ! part of cytoplasm [Term] id: GO:0031503 name: protein-containing complex localization namespace: biological_process def: "A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location." [GOC:mah] synonym: "establishment and maintenance of protein complex localization" EXACT [] synonym: "protein complex localisation" EXACT [GOC:mah] is_a: GO:0051179 ! localization intersection_of: GO:0051179 ! localization intersection_of: RO:0004009 GO:0032991 ! has primary input protein-containing complex relationship: RO:0004009 GO:0032991 ! has primary input protein-containing complex [Term] id: GO:0031514 name: motile cilium namespace: cellular_component def: "A cilium which may have a variable arrangement of axonemal microtubules and also contains molecular motors. It may beat with a whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface, such as on epithelial cells that line the lumenal ducts of various tissues; or they may display a distinct twirling motion that directs fluid flow asymmetrically across the cellular surface to affect asymmetric body plan organization. Motile cilia can be found in single as well as multiple copies per cell." [GOC:cilia, GOC:dgh, GOC:kmv, PMID:17009929, PMID:20144998, PMID:22118931] synonym: "motile cilia" EXACT [] is_a: GO:0005929 ! cilium intersection_of: GO:0005929 ! cilium intersection_of: RO:0002215 GO:0003341 ! capable of cilium movement relationship: RO:0002215 GO:0003341 ! capable of cilium movement [Term] id: GO:0031594 name: neuromuscular junction namespace: cellular_component def: "The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential." [GOC:nln] xref: NIF_Subcellular:sao1124888485 xref: Wikipedia:Neuromuscular_junction is_a: GO:0045202 ! synapse intersection_of: GO:0045202 ! synapse intersection_of: RO:0002131 CL:0000100 ! overlaps motor neuron intersection_of: RO:0002131 CL:0000187 ! overlaps muscle cell relationship: RO:0002131 CL:0000100 ! overlaps motor neuron relationship: RO:0002131 CL:0000187 ! overlaps muscle cell [Term] id: GO:0031644 name: regulation of nervous system process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of the nervous system." [GOC:dph, GOC:mah, GOC:tb] synonym: "regulation of neurological process" EXACT [GOC:dph, GOC:tb] synonym: "regulation of neurological system process" EXACT [] synonym: "regulation of neurophysiological process" EXACT [] is_a: GO:0044057 ! regulation of system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0050877 ! regulates (processual) nervous system process relationship: RO:0002211 GO:0050877 ! regulates (processual) nervous system process [Term] id: GO:0031645 name: negative regulation of nervous system process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a neurophysiological process." [GOC:dph, GOC:mah, GOC:tb] synonym: "down regulation of neurological process" EXACT [] synonym: "down-regulation of neurological process" EXACT [] synonym: "downregulation of neurological process" EXACT [] synonym: "negative regulation of neurological process" EXACT [GOC:dph, GOC:tb] synonym: "negative regulation of neurological system process" EXACT [] synonym: "negative regulation of neurophysiological process" EXACT [] is_a: GO:0031644 ! regulation of nervous system process is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0050877 ! negatively regulates nervous system process relationship: RO:0002212 GO:0050877 ! negatively regulates nervous system process [Term] id: GO:0031646 name: positive regulation of nervous system process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of a neurophysiological process." [GOC:dph, GOC:mah, GOC:tb] synonym: "positive regulation of neurological process" EXACT [GOC:dph, GOC:tb] synonym: "positive regulation of neurological system process" EXACT [] synonym: "positive regulation of neurophysiological process" EXACT [] synonym: "up regulation of neurological process" EXACT [] synonym: "up-regulation of neurological process" EXACT [] synonym: "upregulation of neurological process" EXACT [] is_a: GO:0031644 ! regulation of nervous system process is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0050877 ! positively regulates nervous system process relationship: RO:0002213 GO:0050877 ! positively regulates nervous system process [Term] id: GO:0031965 name: nuclear membrane namespace: cellular_component def: "Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space." [GOC:mah, GOC:pz] xref: NIF_Subcellular:sao1687101204 is_a: GO:0031090 ! organelle membrane intersection_of: GO:0016020 ! membrane intersection_of: BFO:0000050 GO:0005634 ! part of nucleus relationship: BFO:0000050 GO:0005635 ! part of nuclear envelope [Term] id: GO:0031967 name: organelle envelope namespace: cellular_component def: "A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes." [GOC:mah, GOC:pz] is_a: GO:0031975 ! envelope relationship: BFO:0000050 GO:0043227 ! part of membrane-bounded organelle relationship: BFO:0000050 GO:0043229 ! part of intracellular organelle [Term] id: GO:0031968 name: organelle outer membrane namespace: cellular_component def: "The outer, i.e. cytoplasm-facing in a cellular organelle, lipid bilayer of an organelle envelope." [GOC:mah] is_a: GO:0019867 ! outer membrane is_a: GO:0098588 ! bounding membrane of organelle intersection_of: GO:0016020 ! membrane intersection_of: BFO:0000050 GO:0031967 ! part of organelle envelope intersection_of: RO:0002007 GO:0043226 ! bounding layer of organelle relationship: BFO:0000050 GO:0031967 ! part of organelle envelope [Term] id: GO:0031974 name: membrane-enclosed lumen namespace: cellular_component def: "The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen." [GOC:add, GOC:mah] is_a: GO:0110165 ! cellular anatomical entity disjoint_from: GO:0045202 ! synapse [Term] id: GO:0031975 name: envelope namespace: cellular_component def: "A multilayered structure surrounding all or part of a cell; encompasses one or more lipid bilayers, and may include a cell wall layer; also includes the space between layers." [GOC:mah, GOC:pz] is_a: GO:0110165 ! cellular anatomical entity relationship: BFO:0000050 CL:0000000 ! part of cell [Term] id: GO:0031981 name: nuclear lumen namespace: cellular_component def: "The volume enclosed by the nuclear inner membrane." [GOC:mah, GOC:pz] is_a: GO:0070013 ! intracellular organelle lumen relationship: BFO:0000050 GO:0005634 ! part of nucleus [Term] id: GO:0031982 name: vesicle namespace: cellular_component def: "Any small, fluid-filled, spherical organelle enclosed by membrane." [GOC:mah, GOC:pz, GOC:vesicles] xref: NIF_Subcellular:sao221389602 xref: Wikipedia:Vesicle_(biology) is_a: GO:0043227 ! membrane-bounded organelle [Term] id: GO:0031987 name: locomotion involved in locomotory behavior namespace: biological_process def: "Self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement." [GOC:mah] synonym: "locomotion during locomotory behaviour" EXACT [] is_a: GO:0040011 ! locomotion intersection_of: GO:0040011 ! locomotion intersection_of: BFO:0000050 GO:0007626 ! part of locomotory behavior relationship: BFO:0000050 GO:0007626 ! part of locomotory behavior [Term] id: GO:0032024 name: positive regulation of insulin secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of insulin." [GOC:mah] synonym: "up regulation of insulin secretion" EXACT [] synonym: "up-regulation of insulin secretion" EXACT [] synonym: "upregulation of insulin secretion" EXACT [] is_a: GO:0050714 ! positive regulation of protein secretion is_a: GO:0050796 ! regulation of insulin secretion is_a: GO:0090277 ! positive regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030073 ! positively regulates insulin secretion relationship: RO:0002213 GO:0030073 ! positively regulates insulin secretion [Term] id: GO:0032057 name: negative regulation of translational initiation in response to stress namespace: biological_process def: "Any process that stops, prevents or reduces the rate of translation initiation as a result of a stimulus indicating the organism is under stress." [GOC:mah] synonym: "down regulation of translation initiation in response to stress" EXACT [] synonym: "down-regulation of translation initiation in response to stress" EXACT [] synonym: "downregulation of translation initiation in response to stress" EXACT [] is_a: GO:0045947 ! negative regulation of translational initiation intersection_of: GO:0065007 ! biological regulation intersection_of: BFO:0000050 GO:0006950 ! part of response to stress intersection_of: RO:0002212 GO:0006413 ! negatively regulates translational initiation relationship: BFO:0000050 GO:0006950 ! part of response to stress [Term] id: GO:0032058 name: positive regulation of translational initiation in response to stress namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of translation initiation as a result of a stimulus indicating the organism is under stress." [GOC:mah] synonym: "up regulation of translation initiation in response to stress" EXACT [] synonym: "up-regulation of translation initiation in response to stress" EXACT [] synonym: "upregulation of translation initiation in response to stress" EXACT [] is_a: GO:0045948 ! positive regulation of translational initiation intersection_of: GO:0065007 ! biological regulation intersection_of: BFO:0000050 GO:0006950 ! part of response to stress intersection_of: RO:0002213 GO:0006413 ! positively regulates translational initiation relationship: BFO:0000050 GO:0006950 ! part of response to stress [Term] id: GO:0032059 name: bleb namespace: cellular_component def: "A cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Blebs are formed during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses." [GOC:mtg_apoptosis, PMID:12083798, PMID:16624291, Wikipedia:Bleb_(cell_biology)] synonym: "plasma membrane bleb" EXACT [GOC:pr] xref: Wikipedia:Bleb_(cell_biology) is_a: GO:0120025 ! plasma membrane bounded cell projection [Term] id: GO:0032060 name: bleb assembly namespace: biological_process def: "The assembly of a bleb, a cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Plasma membrane blebbing occurs during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses." [GOC:mah, GOC:mtg_apoptosis, PMID:12083798, PMID:16624291, Wikipedia:Bleb_(cell_biology)] synonym: "cell blebbing" EXACT [] synonym: "plasma membrane bleb assembly" EXACT [GOC:pr] synonym: "plasma membrane blebbing" EXACT [GOC:pr] is_a: GO:0120031 ! plasma membrane bounded cell projection assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0032059 ! results in assembly of bleb relationship: RO:0002588 GO:0032059 ! results in assembly of bleb [Term] id: GO:0032069 name: regulation of nuclease activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids." [GOC:mah] is_a: GO:0051336 ! regulation of hydrolase activity is_a: GO:0060255 ! regulation of macromolecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0004518 ! regulates (processual) nuclease activity relationship: RO:0002211 GO:0004518 ! regulates (processual) nuclease activity [Term] id: GO:0032070 name: regulation of deoxyribonuclease activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid." [GOC:mah] is_a: GO:0032069 ! regulation of nuclease activity is_a: GO:0051052 ! regulation of DNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0004536 ! regulates (processual) DNA nuclease activity relationship: RO:0002211 GO:0004536 ! regulates (processual) DNA nuclease activity [Term] id: GO:0032074 name: negative regulation of nuclease activity namespace: biological_process def: "Any process that stops or reduces the rate of nuclease activity, the hydrolysis of ester linkages within nucleic acids." [GOC:mah] synonym: "down regulation of nuclease activity" EXACT [] synonym: "down-regulation of nuclease activity" EXACT [] synonym: "downregulation of nuclease activity" EXACT [] is_a: GO:0032069 ! regulation of nuclease activity is_a: GO:0045934 ! negative regulation of nucleobase-containing compound metabolic process is_a: GO:0051346 ! negative regulation of hydrolase activity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0004518 ! negatively regulates nuclease activity relationship: RO:0002212 GO:0004518 ! negatively regulates nuclease activity [Term] id: GO:0032075 name: positive regulation of nuclease activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids." [GOC:mah] synonym: "up regulation of nuclease activity" EXACT [] synonym: "up-regulation of nuclease activity" EXACT [] synonym: "upregulation of nuclease activity" EXACT [] is_a: GO:0032069 ! regulation of nuclease activity is_a: GO:0045935 ! positive regulation of nucleobase-containing compound metabolic process is_a: GO:0051345 ! positive regulation of hydrolase activity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0004518 ! positively regulates nuclease activity relationship: RO:0002213 GO:0004518 ! positively regulates nuclease activity [Term] id: GO:0032076 name: negative regulation of deoxyribonuclease activity namespace: biological_process def: "Any process that stops or reduces the rate of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid." [GOC:mah] synonym: "down regulation of deoxyribonuclease activity" EXACT [] synonym: "down-regulation of deoxyribonuclease activity" EXACT [] synonym: "downregulation of deoxyribonuclease activity" EXACT [] is_a: GO:0032070 ! regulation of deoxyribonuclease activity is_a: GO:0032074 ! negative regulation of nuclease activity is_a: GO:0051053 ! negative regulation of DNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0004536 ! negatively regulates DNA nuclease activity relationship: RO:0002212 GO:0004536 ! negatively regulates DNA nuclease activity [Term] id: GO:0032077 name: positive regulation of deoxyribonuclease activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid." [GOC:mah] synonym: "up regulation of deoxyribonuclease activity" EXACT [] synonym: "up-regulation of deoxyribonuclease activity" EXACT [] synonym: "upregulation of deoxyribonuclease activity" EXACT [] is_a: GO:0032070 ! regulation of deoxyribonuclease activity is_a: GO:0032075 ! positive regulation of nuclease activity is_a: GO:0051054 ! positive regulation of DNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0004536 ! positively regulates DNA nuclease activity relationship: RO:0002213 GO:0004536 ! positively regulates DNA nuclease activity [Term] id: GO:0032101 name: regulation of response to external stimulus namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a response to an external stimulus." [GOC:mah] is_a: GO:0048583 ! regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0009605 ! regulates (processual) response to external stimulus relationship: RO:0002211 GO:0009605 ! regulates (processual) response to external stimulus [Term] id: GO:0032102 name: negative regulation of response to external stimulus namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an external stimulus." [GOC:mah] synonym: "down regulation of response to external stimulus" EXACT [] synonym: "down-regulation of response to external stimulus" EXACT [] synonym: "downregulation of response to external stimulus" EXACT [] is_a: GO:0032101 ! regulation of response to external stimulus is_a: GO:0048585 ! negative regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0009605 ! negatively regulates response to external stimulus relationship: RO:0002212 GO:0009605 ! negatively regulates response to external stimulus [Term] id: GO:0032103 name: positive regulation of response to external stimulus namespace: biological_process def: "Any process that activates, maintains or increases the rate of a response to an external stimulus." [GOC:mah] synonym: "up regulation of response to external stimulus" EXACT [] synonym: "up-regulation of response to external stimulus" EXACT [] synonym: "upregulation of response to external stimulus" EXACT [] is_a: GO:0032101 ! regulation of response to external stimulus is_a: GO:0048584 ! positive regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0009605 ! positively regulates response to external stimulus relationship: RO:0002213 GO:0009605 ! positively regulates response to external stimulus [Term] id: GO:0032127 name: dense core granule membrane namespace: cellular_component def: "The lipid bilayer surrounding a dense core granule." [GOC:mah] synonym: "dense core vesicle membrane" EXACT [GOC:kmv] is_a: GO:0030667 ! secretory granule membrane intersection_of: GO:0016020 ! membrane intersection_of: RO:0002007 GO:0031045 ! bounding layer of dense core granule relationship: RO:0002007 GO:0031045 ! bounding layer of dense core granule [Term] id: GO:0032222 name: regulation of synaptic transmission, cholinergic namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine." [GOC:mah] is_a: GO:0050804 ! modulation of chemical synaptic transmission intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007271 ! regulates (processual) synaptic transmission, cholinergic relationship: RO:0002211 GO:0007271 ! regulates (processual) synaptic transmission, cholinergic [Term] id: GO:0032223 name: negative regulation of synaptic transmission, cholinergic namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine." [GOC:mah] synonym: "down regulation of synaptic transmission, cholinergic" EXACT [] synonym: "down-regulation of synaptic transmission, cholinergic" EXACT [] synonym: "downregulation of synaptic transmission, cholinergic" EXACT [] is_a: GO:0032222 ! regulation of synaptic transmission, cholinergic is_a: GO:0050805 ! negative regulation of synaptic transmission intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007271 ! negatively regulates synaptic transmission, cholinergic relationship: RO:0002212 GO:0007271 ! negatively regulates synaptic transmission, cholinergic [Term] id: GO:0032224 name: positive regulation of synaptic transmission, cholinergic namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine." [GOC:mah] synonym: "up regulation of synaptic transmission, cholinergic" EXACT [] synonym: "up-regulation of synaptic transmission, cholinergic" EXACT [] synonym: "upregulation of synaptic transmission, cholinergic" EXACT [] is_a: GO:0032222 ! regulation of synaptic transmission, cholinergic is_a: GO:0050806 ! positive regulation of synaptic transmission intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007271 ! positively regulates synaptic transmission, cholinergic relationship: RO:0002213 GO:0007271 ! positively regulates synaptic transmission, cholinergic [Term] id: GO:0032231 name: regulation of actin filament bundle assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the assembly of actin filament bundles." [GOC:mah] synonym: "regulation of actin cable assembly" EXACT [GOC:dph, GOC:tb] is_a: GO:0044087 ! regulation of cellular component biogenesis is_a: GO:0110053 ! regulation of actin filament organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0051017 ! regulates (processual) actin filament bundle assembly relationship: RO:0002211 GO:0051017 ! regulates (processual) actin filament bundle assembly [Term] id: GO:0032232 name: negative regulation of actin filament bundle assembly namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of actin filament bundles." [GOC:mah] synonym: "down regulation of actin filament bundle formation" EXACT [] synonym: "down-regulation of actin filament bundle formation" EXACT [] synonym: "downregulation of actin filament bundle formation" EXACT [] is_a: GO:0032231 ! regulation of actin filament bundle assembly is_a: GO:0051494 ! negative regulation of cytoskeleton organization is_a: GO:1902904 ! negative regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0051017 ! negatively regulates actin filament bundle assembly relationship: RO:0002212 GO:0051017 ! negatively regulates actin filament bundle assembly [Term] id: GO:0032233 name: positive regulation of actin filament bundle assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the assembly of actin filament bundles." [GOC:mah] synonym: "up regulation of actin filament bundle formation" EXACT [] synonym: "up-regulation of actin filament bundle formation" EXACT [] synonym: "upregulation of actin filament bundle formation" EXACT [] is_a: GO:0032231 ! regulation of actin filament bundle assembly is_a: GO:0044089 ! positive regulation of cellular component biogenesis is_a: GO:0051495 ! positive regulation of cytoskeleton organization is_a: GO:1902905 ! positive regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0051017 ! positively regulates actin filament bundle assembly relationship: RO:0002213 GO:0051017 ! positively regulates actin filament bundle assembly [Term] id: GO:0032239 name: regulation of nucleobase-containing compound transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0015931 ! regulates (processual) nucleobase-containing compound transport relationship: RO:0002211 GO:0015931 ! regulates (processual) nucleobase-containing compound transport [Term] id: GO:0032240 name: negative regulation of nucleobase-containing compound transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] synonym: "down regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" EXACT [] synonym: "down-regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" EXACT [] synonym: "downregulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" EXACT [] is_a: GO:0032239 ! regulation of nucleobase-containing compound transport is_a: GO:0051051 ! negative regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0015931 ! negatively regulates nucleobase-containing compound transport relationship: RO:0002212 GO:0015931 ! negatively regulates nucleobase-containing compound transport [Term] id: GO:0032241 name: positive regulation of nucleobase-containing compound transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] synonym: "up regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" EXACT [] synonym: "up-regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" EXACT [] synonym: "upregulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" EXACT [] is_a: GO:0032239 ! regulation of nucleobase-containing compound transport is_a: GO:0051050 ! positive regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0015931 ! positively regulates nucleobase-containing compound transport relationship: RO:0002213 GO:0015931 ! positively regulates nucleobase-containing compound transport [Term] id: GO:0032252 name: secretory granule localization namespace: biological_process def: "Any process in which a secretory granule is transported to, and/or maintained in, a specific location within the cell." [GOC:mah] synonym: "secretory granule localisation" EXACT [GOC:mah] is_a: GO:0051648 ! vesicle localization intersection_of: GO:0051179 ! localization intersection_of: RO:0004009 GO:0030141 ! has primary input secretory granule relationship: RO:0004009 GO:0030141 ! has primary input secretory granule [Term] id: GO:0032253 name: dense core granule localization namespace: biological_process def: "Any process in which a dense core granule is transported to, and/or maintained in, a specific location within the cell." [GOC:mah] synonym: "dense core granule localisation" EXACT [GOC:mah] synonym: "dense core vesicle localization" EXACT [GOC:kmv] is_a: GO:0032252 ! secretory granule localization intersection_of: GO:0051179 ! localization intersection_of: RO:0004009 GO:0031045 ! has primary input dense core granule relationship: RO:0004009 GO:0031045 ! has primary input dense core granule [Term] id: GO:0032271 name: regulation of protein polymerization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the process of creating protein polymers." [GOC:mah] synonym: "regulation of protein polymerisation" EXACT [] is_a: GO:0043254 ! regulation of protein-containing complex assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0051258 ! regulates (processual) protein polymerization relationship: RO:0002211 GO:0051258 ! regulates (processual) protein polymerization [Term] id: GO:0032272 name: negative regulation of protein polymerization namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the process of creating protein polymers." [GOC:mah] synonym: "down regulation of protein polymerization" EXACT [] synonym: "down-regulation of protein polymerization" EXACT [] synonym: "downregulation of protein polymerization" EXACT [] is_a: GO:0031333 ! negative regulation of protein-containing complex assembly is_a: GO:0032271 ! regulation of protein polymerization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0051258 ! negatively regulates protein polymerization relationship: RO:0002212 GO:0051258 ! negatively regulates protein polymerization [Term] id: GO:0032273 name: positive regulation of protein polymerization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the process of creating protein polymers." [GOC:mah] synonym: "up regulation of protein polymerization" EXACT [] synonym: "up-regulation of protein polymerization" EXACT [] synonym: "upregulation of protein polymerization" EXACT [] is_a: GO:0031334 ! positive regulation of protein-containing complex assembly is_a: GO:0032271 ! regulation of protein polymerization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0051258 ! positively regulates protein polymerization relationship: RO:0002213 GO:0051258 ! positively regulates protein polymerization [Term] id: GO:0032330 name: regulation of chondrocyte differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of chondrocyte differentiation." [GOC:mah] is_a: GO:0045595 ! regulation of cell differentiation is_a: GO:0061035 ! regulation of cartilage development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002062 ! regulates (processual) chondrocyte differentiation relationship: RO:0002211 GO:0002062 ! regulates (processual) chondrocyte differentiation [Term] id: GO:0032331 name: negative regulation of chondrocyte differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of chondrocyte differentiation." [GOC:mah] synonym: "down regulation of chondrocyte differentiation" EXACT [] synonym: "down-regulation of chondrocyte differentiation" EXACT [] synonym: "downregulation of chondrocyte differentiation" EXACT [] is_a: GO:0032330 ! regulation of chondrocyte differentiation is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0061037 ! negative regulation of cartilage development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002062 ! negatively regulates chondrocyte differentiation relationship: RO:0002212 GO:0002062 ! negatively regulates chondrocyte differentiation [Term] id: GO:0032332 name: positive regulation of chondrocyte differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of chondrocyte differentiation." [GOC:mah] synonym: "up regulation of chondrocyte differentiation" EXACT [] synonym: "up-regulation of chondrocyte differentiation" EXACT [] synonym: "upregulation of chondrocyte differentiation" EXACT [] is_a: GO:0032330 ! regulation of chondrocyte differentiation is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0061036 ! positive regulation of cartilage development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002062 ! positively regulates chondrocyte differentiation relationship: RO:0002213 GO:0002062 ! positively regulates chondrocyte differentiation [Term] id: GO:0032365 name: intracellular lipid transport namespace: biological_process def: "The directed movement of lipids within cells." [GOC:mah] is_a: GO:0006869 ! lipid transport is_a: GO:0046907 ! intracellular transport intersection_of: GO:0006810 ! transport intersection_of: BFO:0000066 GO:0005622 ! occurs in intracellular anatomical structure intersection_of: RO:0004009 CHEBI:18059 ! has primary input lipid [Term] id: GO:0032368 name: regulation of lipid transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] is_a: GO:0051049 ! regulation of transport is_a: GO:1905952 ! regulation of lipid localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006869 ! regulates (processual) lipid transport relationship: RO:0002211 GO:0006869 ! regulates (processual) lipid transport [Term] id: GO:0032369 name: negative regulation of lipid transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] synonym: "down regulation of lipid transport" EXACT [] synonym: "down-regulation of lipid transport" EXACT [] synonym: "downregulation of lipid transport" EXACT [] is_a: GO:0032368 ! regulation of lipid transport is_a: GO:0051051 ! negative regulation of transport is_a: GO:1905953 ! negative regulation of lipid localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006869 ! negatively regulates lipid transport relationship: RO:0002212 GO:0006869 ! negatively regulates lipid transport [Term] id: GO:0032370 name: positive regulation of lipid transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] synonym: "up regulation of lipid transport" EXACT [] synonym: "up-regulation of lipid transport" EXACT [] synonym: "upregulation of lipid transport" EXACT [] is_a: GO:0032368 ! regulation of lipid transport is_a: GO:0051050 ! positive regulation of transport is_a: GO:1905954 ! positive regulation of lipid localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006869 ! positively regulates lipid transport relationship: RO:0002213 GO:0006869 ! positively regulates lipid transport [Term] id: GO:0032377 name: regulation of intracellular lipid transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of lipids within cells." [GOC:mah] is_a: GO:0032368 ! regulation of lipid transport is_a: GO:0032386 ! regulation of intracellular transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0032365 ! regulates (processual) intracellular lipid transport relationship: RO:0002211 GO:0032365 ! regulates (processual) intracellular lipid transport [Term] id: GO:0032378 name: negative regulation of intracellular lipid transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids within cells." [GOC:mah] synonym: "down regulation of intracellular lipid transport" EXACT [] synonym: "down-regulation of intracellular lipid transport" EXACT [] synonym: "downregulation of intracellular lipid transport" EXACT [] is_a: GO:0032369 ! negative regulation of lipid transport is_a: GO:0032377 ! regulation of intracellular lipid transport is_a: GO:0032387 ! negative regulation of intracellular transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0032365 ! negatively regulates intracellular lipid transport relationship: RO:0002212 GO:0032365 ! negatively regulates intracellular lipid transport [Term] id: GO:0032379 name: positive regulation of intracellular lipid transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the directed movement of lipids within cells." [GOC:mah] synonym: "up regulation of intracellular lipid transport" EXACT [] synonym: "up-regulation of intracellular lipid transport" EXACT [] synonym: "upregulation of intracellular lipid transport" EXACT [] is_a: GO:0032370 ! positive regulation of lipid transport is_a: GO:0032377 ! regulation of intracellular lipid transport is_a: GO:0032388 ! positive regulation of intracellular transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0032365 ! positively regulates intracellular lipid transport relationship: RO:0002213 GO:0032365 ! positively regulates intracellular lipid transport [Term] id: GO:0032386 name: regulation of intracellular transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of substances within cells." [GOC:mah] is_a: GO:0051049 ! regulation of transport is_a: GO:0060341 ! regulation of cellular localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0046907 ! regulates (processual) intracellular transport relationship: RO:0002211 GO:0046907 ! regulates (processual) intracellular transport [Term] id: GO:0032387 name: negative regulation of intracellular transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells." [GOC:mah] synonym: "down regulation of intracellular transport" EXACT [] synonym: "down-regulation of intracellular transport" EXACT [] synonym: "downregulation of intracellular transport" EXACT [] is_a: GO:0032386 ! regulation of intracellular transport is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:0051051 ! negative regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0046907 ! negatively regulates intracellular transport relationship: RO:0002212 GO:0046907 ! negatively regulates intracellular transport [Term] id: GO:0032388 name: positive regulation of intracellular transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the directed movement of substances within cells." [GOC:mah] synonym: "up regulation of intracellular transport" EXACT [] synonym: "up-regulation of intracellular transport" EXACT [] synonym: "upregulation of intracellular transport" EXACT [] is_a: GO:0032386 ! regulation of intracellular transport is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:0051050 ! positive regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0046907 ! positively regulates intracellular transport relationship: RO:0002213 GO:0046907 ! positively regulates intracellular transport [Term] id: GO:0032409 name: regulation of transporter activity namespace: biological_process def: "Any process that modulates the activity of a transporter." [GOC:mah] is_a: GO:0065009 ! regulation of molecular function intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0005215 ! regulates (processual) transporter activity relationship: RO:0002211 GO:0005215 ! regulates (processual) transporter activity [Term] id: GO:0032410 name: negative regulation of transporter activity namespace: biological_process def: "Any process that stops or reduces the activity of a transporter." [GOC:mah] synonym: "down regulation of transporter activity" EXACT [] synonym: "down-regulation of transporter activity" EXACT [] synonym: "downregulation of transporter activity" EXACT [] is_a: GO:0032409 ! regulation of transporter activity is_a: GO:0044092 ! negative regulation of molecular function is_a: GO:0051051 ! negative regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0005215 ! negatively regulates transporter activity relationship: RO:0002212 GO:0005215 ! negatively regulates transporter activity [Term] id: GO:0032411 name: positive regulation of transporter activity namespace: biological_process def: "Any process that activates or increases the activity of a transporter." [GOC:mah] synonym: "up regulation of transporter activity" EXACT [] synonym: "up-regulation of transporter activity" EXACT [] synonym: "upregulation of transporter activity" EXACT [] is_a: GO:0032409 ! regulation of transporter activity is_a: GO:0044093 ! positive regulation of molecular function is_a: GO:0051050 ! positive regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0005215 ! positively regulates transporter activity relationship: RO:0002213 GO:0005215 ! positively regulates transporter activity [Term] id: GO:0032412 name: regulation of monoatomic ion transmembrane transporter activity namespace: biological_process def: "Any process that modulates the activity of an ion transporter." [GOC:mah, GOC:tb] synonym: "regulation of ion transporter activity" EXACT [GOC:tb] is_a: GO:0022898 ! regulation of transmembrane transporter activity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0015075 ! regulates (processual) monoatomic ion transmembrane transporter activity relationship: RO:0002211 GO:0015075 ! regulates (processual) monoatomic ion transmembrane transporter activity [Term] id: GO:0032413 name: negative regulation of ion transmembrane transporter activity namespace: biological_process def: "Any process that stops or reduces the activity of an ion transporter." [GOC:mah, GOC:tb] synonym: "down regulation of ion transporter activity" EXACT [] synonym: "down-regulation of ion transporter activity" EXACT [] synonym: "downregulation of ion transporter activity" EXACT [] synonym: "negative regulation of ion transporter activity" EXACT [GOC:tb] is_a: GO:0032410 ! negative regulation of transporter activity is_a: GO:0032412 ! regulation of monoatomic ion transmembrane transporter activity is_a: GO:0034766 ! negative regulation of monoatomic ion transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0015075 ! negatively regulates monoatomic ion transmembrane transporter activity relationship: RO:0002212 GO:0015075 ! negatively regulates monoatomic ion transmembrane transporter activity [Term] id: GO:0032414 name: positive regulation of ion transmembrane transporter activity namespace: biological_process def: "Any process that activates or increases the activity of an ion transporter." [GOC:mah, GOC:tb] synonym: "positive regulation of ion transporter activity" EXACT [GOC:tb] synonym: "up regulation of ion transporter activity" EXACT [] synonym: "up-regulation of ion transporter activity" EXACT [] synonym: "upregulation of ion transporter activity" EXACT [] is_a: GO:0032411 ! positive regulation of transporter activity is_a: GO:0032412 ! regulation of monoatomic ion transmembrane transporter activity is_a: GO:0034767 ! positive regulation of monoatomic ion transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0015075 ! positively regulates monoatomic ion transmembrane transporter activity relationship: RO:0002213 GO:0015075 ! positively regulates monoatomic ion transmembrane transporter activity [Term] id: GO:0032432 name: actin filament bundle namespace: cellular_component def: "An assembly of actin filaments that are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness." [GOC:mah] is_a: GO:0110165 ! cellular anatomical entity relationship: BFO:0000050 GO:0015629 ! part of actin cytoskeleton relationship: BFO:0000051 GO:0005884 ! has part actin filament [Term] id: GO:0032501 name: multicellular organismal process namespace: biological_process def: "Any biological process, occurring at the level of a multicellular organism, pertinent to its function." [GOC:curators, GOC:dph, GOC:isa_complete, GOC:tb] synonym: "organismal physiological process" EXACT [] is_a: GO:0008150 ! biological_process creation_date: 2012-09-19T16:07:47Z [Term] id: GO:0032502 name: developmental process namespace: biological_process def: "A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition." [GOC:isa_complete] is_a: GO:0008150 ! biological_process creation_date: 2012-12-19T12:21:31Z [Term] id: GO:0032504 name: multicellular organism reproduction namespace: biological_process def: "The biological process in which new individuals are produced by one or two multicellular organisms. The new individuals inherit some proportion of their genetic material from the parent or parents." [GOC:isa_complete, GOC:jid] is_a: GO:0000003 ! reproduction is_a: GO:0032501 ! multicellular organismal process [Term] id: GO:0032528 name: microvillus organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell." [GOC:mah] synonym: "microvillus organisation" EXACT [GOC:mah] is_a: GO:0120036 ! plasma membrane bounded cell projection organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0005902 ! results in organization of microvillus relationship: RO:0002592 GO:0005902 ! results in organization of microvillus [Term] id: GO:0032530 name: regulation of microvillus organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus." [GOC:mah] synonym: "regulation of microvillus organisation" EXACT [GOC:mah] is_a: GO:0120035 ! regulation of plasma membrane bounded cell projection organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0032528 ! regulates (processual) microvillus organization relationship: RO:0002211 GO:0032528 ! regulates (processual) microvillus organization [Term] id: GO:0032534 name: regulation of microvillus assembly namespace: biological_process def: "A process that modulates the formation of a microvillus." [GOC:mah] is_a: GO:0032530 ! regulation of microvillus organization is_a: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030033 ! regulates (processual) microvillus assembly relationship: RO:0002211 GO:0030033 ! regulates (processual) microvillus assembly [Term] id: GO:0032589 name: neuron projection membrane namespace: cellular_component def: "The portion of the plasma membrane surrounding a neuron projection." [GOC:mah] is_a: GO:0031253 ! cell projection membrane is_a: GO:0031256 ! leading edge membrane intersection_of: GO:0016020 ! membrane intersection_of: RO:0002007 GO:0043005 ! bounding layer of neuron projection relationship: RO:0002007 GO:0043005 ! bounding layer of neuron projection [Term] id: GO:0032594 name: protein transport within lipid bilayer namespace: biological_process def: "The directed movement of a protein from one location to another within a lipid bilayer." [GOC:mah] synonym: "protein translocation within membrane" EXACT [] is_a: GO:0006886 ! intracellular protein transport is_a: GO:0061024 ! membrane organization intersection_of: GO:0015031 ! protein transport intersection_of: BFO:0000066 GO:0016020 ! occurs in membrane relationship: BFO:0000066 GO:0016020 ! occurs in membrane [Term] id: GO:0032774 name: RNA biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. Refers not only to transcription but also to e.g. viral RNA replication." [GOC:mah, GOC:txnOH] synonym: "RNA anabolism" EXACT [] synonym: "RNA biosynthesis" EXACT [] synonym: "RNA formation" EXACT [] synonym: "RNA synthesis" EXACT [] is_a: GO:0009059 ! macromolecule biosynthetic process is_a: GO:0016070 ! RNA metabolic process is_a: GO:0034654 ! nucleobase-containing compound biosynthetic process intersection_of: GO:0009059 ! macromolecule biosynthetic process intersection_of: RO:0004008 CHEBI:33697 ! has primary output ribonucleic acid relationship: RO:0004008 CHEBI:33697 ! has primary output ribonucleic acid [Term] id: GO:0032782 name: bile acid secretion namespace: biological_process def: "The regulated release of bile acid, composed of any of a group of steroid carboxylic acids occurring in bile, by a cell or a tissue." [GOC:ecd] is_a: GO:0015718 ! monocarboxylic acid transport is_a: GO:0046717 ! acid secretion intersection_of: GO:0046903 ! secretion intersection_of: RO:0004009 CHEBI:36235 ! has primary input bile acid anion relationship: RO:0004009 CHEBI:36235 ! has primary input bile acid anion [Term] id: GO:0032787 name: monocarboxylic acid metabolic process namespace: biological_process def: "The chemical reactions and pathways involving monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-)." [GOC:vk] synonym: "monocarboxylate metabolic process" EXACT [] synonym: "monocarboxylic acid metabolism" EXACT [] is_a: GO:0019752 ! carboxylic acid metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:35757 ! has primary input or output monocarboxylic acid anion relationship: RO:0004007 CHEBI:35757 ! has primary input or output monocarboxylic acid anion [Term] id: GO:0032790 name: ribosome disassembly namespace: biological_process def: "The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits." [GOC:mah, GOC:vk] is_a: GO:1903008 ! organelle disassembly intersection_of: GO:0022411 ! cellular component disassembly intersection_of: RO:0002590 GO:0005840 ! results in disassembly of ribosome relationship: RO:0002590 GO:0005840 ! results in disassembly of ribosome [Term] id: GO:0032838 name: plasma membrane bounded cell projection cytoplasm namespace: cellular_component def: "All of the contents of a plasma membrane bounded cell projection, excluding the plasma membrane surrounding the projection." [GOC:krc, GOC:mah] is_a: GO:0099568 ! cytoplasmic region intersection_of: GO:0005737 ! cytoplasm intersection_of: BFO:0000050 GO:0120025 ! part of plasma membrane bounded cell projection relationship: BFO:0000050 GO:0120025 ! part of plasma membrane bounded cell projection [Term] id: GO:0032868 name: response to insulin namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms." [GOC:mah, ISBN:0198506732] synonym: "response to insulin stimulus" EXACT [GOC:dos] is_a: GO:0043434 ! response to peptide hormone intersection_of: GO:0042221 ! response to chemical intersection_of: RO:0004009 PR:000009054 ! has primary input insulin gene translation product relationship: RO:0004009 PR:000009054 ! has primary input insulin gene translation product [Term] id: GO:0032871 name: regulation of karyogamy namespace: biological_process def: "Any process that modulates the frequency, rate or extent of karyogamy, the creation of a single nucleus from multiple nuclei as a result of membrane fusion." [GOC:mah] is_a: GO:1903353 ! regulation of nucleus organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0000741 ! regulates (processual) karyogamy relationship: RO:0002211 GO:0000741 ! regulates (processual) karyogamy [Term] id: GO:0032878 name: regulation of establishment or maintenance of cell polarity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns." [GOC:mah] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007163 ! regulates (processual) establishment or maintenance of cell polarity relationship: RO:0002211 GO:0007163 ! regulates (processual) establishment or maintenance of cell polarity [Term] id: GO:0032879 name: regulation of localization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location." [GOC:mah] synonym: "regulation of localisation" EXACT [GOC:mah] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0051179 ! regulates (processual) localization relationship: RO:0002211 GO:0051179 ! regulates (processual) localization [Term] id: GO:0032880 name: regulation of protein localization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location." [GOC:dph, GOC:mah, GOC:tb] synonym: "regulation of cellular protein localisation" EXACT [GOC:TermGenie] synonym: "regulation of cellular protein localization" EXACT [] synonym: "regulation of protein localisation" EXACT [GOC:mah] is_a: GO:0060341 ! regulation of cellular localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0008104 ! regulates (processual) protein localization relationship: RO:0002211 GO:0008104 ! regulates (processual) protein localization creation_date: 2015-01-20T14:32:14Z [Term] id: GO:0032881 name: regulation of polysaccharide metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving polysaccharides." [GOC:mah] is_a: GO:0006109 ! regulation of carbohydrate metabolic process is_a: GO:0060255 ! regulation of macromolecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0005976 ! regulates (processual) polysaccharide metabolic process relationship: RO:0002211 GO:0005976 ! regulates (processual) polysaccharide metabolic process [Term] id: GO:0032882 name: regulation of chitin metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chitin." [GOC:mah] synonym: "regulation of chitin metabolism" EXACT [] is_a: GO:0032881 ! regulation of polysaccharide metabolic process is_a: GO:0051171 ! regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006030 ! regulates (processual) chitin metabolic process relationship: RO:0002211 GO:0006030 ! regulates (processual) chitin metabolic process [Term] id: GO:0032883 name: regulation of chitin biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chitin." [GOC:mah] synonym: "regulation of chitin anabolism" EXACT [] synonym: "regulation of chitin formation" EXACT [] synonym: "regulation of chitin synthesis" EXACT [] is_a: GO:0032882 ! regulation of chitin metabolic process is_a: GO:0032885 ! regulation of polysaccharide biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006031 ! regulates (processual) chitin biosynthetic process relationship: RO:0002211 GO:0006031 ! regulates (processual) chitin biosynthetic process [Term] id: GO:0032885 name: regulation of polysaccharide biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides." [GOC:mah] is_a: GO:0010556 ! regulation of macromolecule biosynthetic process is_a: GO:0032881 ! regulation of polysaccharide metabolic process is_a: GO:0043255 ! regulation of carbohydrate biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0000271 ! regulates (processual) polysaccharide biosynthetic process relationship: RO:0002211 GO:0000271 ! regulates (processual) polysaccharide biosynthetic process [Term] id: GO:0032886 name: regulation of microtubule-based process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton." [GOC:mah] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007017 ! regulates (processual) microtubule-based process relationship: RO:0002211 GO:0007017 ! regulates (processual) microtubule-based process [Term] id: GO:0032890 name: regulation of organic acid transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0015849 ! regulates (processual) organic acid transport relationship: RO:0002211 GO:0015849 ! regulates (processual) organic acid transport [Term] id: GO:0032891 name: negative regulation of organic acid transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] synonym: "down regulation of organic acid transport" EXACT [] synonym: "down-regulation of organic acid transport" EXACT [] synonym: "downregulation of organic acid transport" EXACT [] is_a: GO:0032890 ! regulation of organic acid transport is_a: GO:0051051 ! negative regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0015849 ! negatively regulates organic acid transport relationship: RO:0002212 GO:0015849 ! negatively regulates organic acid transport [Term] id: GO:0032892 name: positive regulation of organic acid transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] synonym: "up regulation of organic acid transport" EXACT [] synonym: "up-regulation of organic acid transport" EXACT [] synonym: "upregulation of organic acid transport" EXACT [] is_a: GO:0032890 ! regulation of organic acid transport is_a: GO:0051050 ! positive regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0015849 ! positively regulates organic acid transport relationship: RO:0002213 GO:0015849 ! positively regulates organic acid transport [Term] id: GO:0032940 name: secretion by cell namespace: biological_process def: "The controlled release of a substance by a cell." [GOC:mah] synonym: "cellular secretion" EXACT [] xref: Wikipedia:Secretion is_a: GO:0046903 ! secretion is_a: GO:0140352 ! export from cell [Term] id: GO:0032941 name: secretion by tissue namespace: biological_process def: "The controlled release of a substance by a tissue." [GOC:mah] synonym: "tissue secretion" EXACT [] is_a: GO:0032501 ! multicellular organismal process is_a: GO:0046903 ! secretion [Term] id: GO:0032943 name: mononuclear cell proliferation namespace: biological_process def: "The expansion of a mononuclear cell population by cell division. A mononuclear cell is a leukocyte with a single non-segmented nucleus in the mature form." [GOC:add] is_a: GO:0070661 ! leukocyte proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000842 ! acts on population of mononuclear cell relationship: RO:0012003 CL:0000842 ! acts on population of mononuclear cell [Term] id: GO:0032944 name: regulation of mononuclear cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mononuclear cell proliferation." [GOC:add] is_a: GO:0070663 ! regulation of leukocyte proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0032943 ! regulates (processual) mononuclear cell proliferation relationship: RO:0002211 GO:0032943 ! regulates (processual) mononuclear cell proliferation [Term] id: GO:0032945 name: negative regulation of mononuclear cell proliferation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of mononuclear cell proliferation." [GOC:add] is_a: GO:0032944 ! regulation of mononuclear cell proliferation is_a: GO:0070664 ! negative regulation of leukocyte proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0032943 ! negatively regulates mononuclear cell proliferation relationship: RO:0002212 GO:0032943 ! negatively regulates mononuclear cell proliferation [Term] id: GO:0032946 name: positive regulation of mononuclear cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mononuclear cell proliferation." [GOC:add] synonym: "up regulation of mononuclear cell proliferation" EXACT [] synonym: "up-regulation of mononuclear cell proliferation" EXACT [] synonym: "upregulation of mononuclear cell proliferation" EXACT [] is_a: GO:0032944 ! regulation of mononuclear cell proliferation is_a: GO:0070665 ! positive regulation of leukocyte proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0032943 ! positively regulates mononuclear cell proliferation relationship: RO:0002213 GO:0032943 ! positively regulates mononuclear cell proliferation [Term] id: GO:0032956 name: regulation of actin cytoskeleton organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins." [GOC:mah] synonym: "regulation of actin cytoskeleton organisation" EXACT [GOC:mah] is_a: GO:0032970 ! regulation of actin filament-based process is_a: GO:0051493 ! regulation of cytoskeleton organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030036 ! regulates (processual) actin cytoskeleton organization relationship: RO:0002211 GO:0030036 ! regulates (processual) actin cytoskeleton organization [Term] id: GO:0032963 name: collagen metabolic process namespace: biological_process def: "The chemical reactions and pathways involving collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%)." [GOC:mah, ISBN:0198506732] synonym: "collagen metabolism" EXACT [] is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 GO:0005581 ! has primary input or output collagen trimer relationship: RO:0004007 GO:0005581 ! has primary input or output collagen trimer [Term] id: GO:0032964 name: collagen biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%)." [GOC:mah, ISBN:0198506732] synonym: "collagen anabolism" EXACT [] synonym: "collagen biosynthesis" EXACT [] synonym: "collagen formation" EXACT [] synonym: "collagen synthesis" EXACT [] is_a: GO:0009058 ! biosynthetic process is_a: GO:0032963 ! collagen metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 GO:0005581 ! has primary output collagen trimer relationship: RO:0004008 GO:0005581 ! has primary output collagen trimer [Term] id: GO:0032965 name: regulation of collagen biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." [GOC:mah] synonym: "regulation of collagen anabolism" EXACT [] synonym: "regulation of collagen biosynthesis" EXACT [] synonym: "regulation of collagen formation" EXACT [] synonym: "regulation of collagen synthesis" EXACT [] is_a: GO:0009889 ! regulation of biosynthetic process is_a: GO:0010712 ! regulation of collagen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0032964 ! regulates (processual) collagen biosynthetic process relationship: RO:0002211 GO:0032964 ! regulates (processual) collagen biosynthetic process [Term] id: GO:0032966 name: negative regulation of collagen biosynthetic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." [GOC:mah] synonym: "negative regulation of collagen anabolism" EXACT [] synonym: "negative regulation of collagen biosynthesis" EXACT [] synonym: "negative regulation of collagen formation" EXACT [] synonym: "negative regulation of collagen synthesis" EXACT [] is_a: GO:0009890 ! negative regulation of biosynthetic process is_a: GO:0010713 ! negative regulation of collagen metabolic process is_a: GO:0032965 ! regulation of collagen biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0032964 ! negatively regulates collagen biosynthetic process relationship: RO:0002212 GO:0032964 ! negatively regulates collagen biosynthetic process [Term] id: GO:0032967 name: positive regulation of collagen biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." [GOC:mah] synonym: "positive regulation of collagen anabolism" EXACT [] synonym: "positive regulation of collagen biosynthesis" EXACT [] synonym: "positive regulation of collagen formation" EXACT [] synonym: "positive regulation of collagen synthesis" EXACT [] is_a: GO:0009891 ! positive regulation of biosynthetic process is_a: GO:0010714 ! positive regulation of collagen metabolic process is_a: GO:0032965 ! regulation of collagen biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0032964 ! positively regulates collagen biosynthetic process relationship: RO:0002213 GO:0032964 ! positively regulates collagen biosynthetic process [Term] id: GO:0032970 name: regulation of actin filament-based process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the actin cytoskeleton." [GOC:mah] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030029 ! regulates (processual) actin filament-based process relationship: RO:0002211 GO:0030029 ! regulates (processual) actin filament-based process [Term] id: GO:0032984 name: protein-containing complex disassembly namespace: biological_process def: "The disaggregation of a protein-containing macromolecular complex into its constituent components." [GOC:mah] synonym: "protein complex disassembly" EXACT [] is_a: GO:0022411 ! cellular component disassembly is_a: GO:0043933 ! protein-containing complex organization intersection_of: GO:0022411 ! cellular component disassembly intersection_of: RO:0002590 GO:0032991 ! results in disassembly of protein-containing complex relationship: RO:0002590 GO:0032991 ! results in disassembly of protein-containing complex [Term] id: GO:0032986 name: protein-DNA complex disassembly namespace: biological_process def: "The disaggregation of a protein-DNA complex into its constituent components." [GOC:mah] synonym: "DNA-protein complex disassembly" EXACT [GOC:mah] is_a: GO:0032984 ! protein-containing complex disassembly is_a: GO:0071824 ! protein-DNA complex organization intersection_of: GO:0022411 ! cellular component disassembly intersection_of: RO:0002590 GO:0032993 ! results in disassembly of protein-DNA complex relationship: RO:0002590 GO:0032993 ! results in disassembly of protein-DNA complex [Term] id: GO:0032988 name: protein-RNA complex disassembly namespace: biological_process def: "The disaggregation of a protein-RNA complex into its constituent components." [GOC:mah] synonym: "ribonucleoprotein complex disassembly" EXACT [] synonym: "RNA-protein complex disassembly" EXACT [] synonym: "RNP complex disassembly" EXACT [] is_a: GO:0032984 ! protein-containing complex disassembly is_a: GO:0071826 ! protein-RNA complex organization intersection_of: GO:0022411 ! cellular component disassembly intersection_of: RO:0002590 GO:1990904 ! results in disassembly of ribonucleoprotein complex relationship: RO:0002590 GO:1990904 ! results in disassembly of ribonucleoprotein complex [Term] id: GO:0032989 name: cellular anatomical entity morphogenesis namespace: biological_process def: "The process in which a cellular entity is generated and organized. A cellular entity has granularity above the level of a protein complex but below that of an anatomical system." [GOC:dph, GOC:mah, GOC:tb] synonym: "cellular component morphogenesis" EXACT [] synonym: "cellular structure morphogenesis" EXACT [GOC:dph, GOC:tb] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 GO:0110165 ! results in morphogenesis of cellular anatomical entity relationship: RO:0002298 GO:0110165 ! results in morphogenesis of cellular anatomical entity [Term] id: GO:0032991 name: protein-containing complex namespace: cellular_component def: "A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together." [GOC:dos, GOC:mah] synonym: "macromolecular complex" EXACT [] synonym: "macromolecule complex" EXACT [] synonym: "protein containing complex" EXACT [] is_a: GO:0005575 ! cellular_component is_a: PR:000050567 ! protein-containing material entity disjoint_from: GO:0110165 ! cellular anatomical entity [Term] id: GO:0032993 name: protein-DNA complex namespace: cellular_component def: "A macromolecular complex containing both protein and DNA molecules." [GOC:mah] synonym: "DNA-protein complex" EXACT [GOC:mah] is_a: GO:0032991 ! protein-containing complex relationship: BFO:0000051 CHEBI:16991 ! has part deoxyribonucleic acid [Term] id: GO:0033002 name: muscle cell proliferation namespace: biological_process def: "The expansion of a muscle cell population by cell division." [CL:0000187, GOC:mah] synonym: "myocyte proliferation" EXACT [] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000187 ! acts on population of muscle cell relationship: RO:0012003 CL:0000187 ! acts on population of muscle cell [Term] id: GO:0033013 name: tetrapyrrole metabolic process namespace: biological_process def: "The chemical reactions and pathways involving tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next." [GOC:mah] synonym: "tetrapyrrole metabolism" EXACT [] is_a: GO:0006725 ! cellular aromatic compound metabolic process is_a: GO:0046483 ! heterocycle metabolic process is_a: GO:1901360 ! organic cyclic compound metabolic process is_a: GO:1901564 ! organonitrogen compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:26932 ! has primary input or output tetrapyrrole relationship: RO:0004007 CHEBI:26932 ! has primary input or output tetrapyrrole [Term] id: GO:0033014 name: tetrapyrrole biosynthetic process namespace: biological_process def: "The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next." [GOC:mah] synonym: "tetrapyrrole anabolism" EXACT [] synonym: "tetrapyrrole biosynthesis" EXACT [] synonym: "tetrapyrrole formation" EXACT [] synonym: "tetrapyrrole synthesis" EXACT [] is_a: GO:0018130 ! heterocycle biosynthetic process is_a: GO:0019438 ! aromatic compound biosynthetic process is_a: GO:0033013 ! tetrapyrrole metabolic process is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process is_a: GO:1901362 ! organic cyclic compound biosynthetic process is_a: GO:1901566 ! organonitrogen compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:26932 ! has primary output tetrapyrrole relationship: RO:0004008 CHEBI:26932 ! has primary output tetrapyrrole [Term] id: GO:0033015 name: tetrapyrrole catabolic process namespace: biological_process def: "The chemical reactions and pathways leading to the breakdown of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next." [GOC:mah] synonym: "tetrapyrrole breakdown" EXACT [] synonym: "tetrapyrrole catabolism" EXACT [] synonym: "tetrapyrrole degradation" EXACT [] is_a: GO:0019439 ! aromatic compound catabolic process is_a: GO:0033013 ! tetrapyrrole metabolic process is_a: GO:0044270 ! cellular nitrogen compound catabolic process is_a: GO:0046700 ! heterocycle catabolic process is_a: GO:1901361 ! organic cyclic compound catabolic process is_a: GO:1901565 ! organonitrogen compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:26932 ! has primary input tetrapyrrole relationship: RO:0004009 CHEBI:26932 ! has primary input tetrapyrrole [Term] id: GO:0033028 name: myeloid cell apoptotic process namespace: biological_process def: "Any apoptotic process in a myeloid cell, a cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage." [CL:0000763, GOC:add, GOC:mtg_apoptosis, PMID:11292031, PMID:15330259, PMID:17133093] synonym: "apoptosis of myeloid cells" EXACT [] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000763 ! occurs in myeloid cell relationship: BFO:0000066 CL:0000763 ! occurs in myeloid cell [Term] id: GO:0033032 name: regulation of myeloid cell apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of myeloid cell apoptotic process." [GOC:add, GOC:mtg_apoptosis] is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0033028 ! regulates (processual) myeloid cell apoptotic process relationship: RO:0002211 GO:0033028 ! regulates (processual) myeloid cell apoptotic process [Term] id: GO:0033033 name: negative regulation of myeloid cell apoptotic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of a myeloid cell apoptotic process." [GOC:add, GOC:mtg_apoptosis] synonym: "down regulation of myeloid cell apoptosis" EXACT [] synonym: "down-regulation of myeloid cell apoptosis" EXACT [] synonym: "downregulation of myeloid cell apoptosis" EXACT [] is_a: GO:0033032 ! regulation of myeloid cell apoptotic process is_a: GO:0043066 ! negative regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0033028 ! negatively regulates myeloid cell apoptotic process relationship: RO:0002212 GO:0033028 ! negatively regulates myeloid cell apoptotic process [Term] id: GO:0033034 name: positive regulation of myeloid cell apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of myeloid cell apoptotic process." [GOC:add, GOC:mtg_apoptosis] synonym: "up regulation of myeloid cell apoptosis" EXACT [] synonym: "up-regulation of myeloid cell apoptosis" EXACT [] synonym: "upregulation of myeloid cell apoptosis" EXACT [] is_a: GO:0033032 ! regulation of myeloid cell apoptotic process is_a: GO:0043065 ! positive regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0033028 ! positively regulates myeloid cell apoptotic process relationship: RO:0002213 GO:0033028 ! positively regulates myeloid cell apoptotic process [Term] id: GO:0033036 name: macromolecule localization namespace: biological_process def: "Any process in which a macromolecule is transported to, or maintained in, a specific location." [GOC:mah] synonym: "macromolecule localisation" EXACT [GOC:mah] is_a: GO:0051179 ! localization [Term] id: GO:0033037 name: polysaccharide localization namespace: biological_process def: "Any process in which a polysaccharide is transported to, or maintained in, a specific location." [GOC:mah] synonym: "polysaccharide localisation" EXACT [GOC:mah] is_a: GO:0033036 ! macromolecule localization intersection_of: GO:0033036 ! macromolecule localization intersection_of: RO:0004009 CHEBI:18154 ! has primary input polysaccharide relationship: RO:0004009 CHEBI:18154 ! has primary input polysaccharide [Term] id: GO:0033043 name: regulation of organelle organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle." [GOC:mah] synonym: "regulation of organelle organisation" EXACT [GOC:mah] is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006996 ! regulates (processual) organelle organization relationship: RO:0002211 GO:0006996 ! regulates (processual) organelle organization [Term] id: GO:0033044 name: regulation of chromosome organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a chromosome." [GOC:mah] synonym: "regulation of chromosome organisation" EXACT [GOC:mah] is_a: GO:0033043 ! regulation of organelle organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0051276 ! regulates (processual) chromosome organization relationship: RO:0002211 GO:0051276 ! regulates (processual) chromosome organization [Term] id: GO:0033045 name: regulation of sister chromatid segregation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of sister chromatid segregation." [GOC:mah] is_a: GO:0033044 ! regulation of chromosome organization is_a: GO:0051983 ! regulation of chromosome segregation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0000819 ! regulates (processual) sister chromatid segregation relationship: RO:0002211 GO:0000819 ! regulates (processual) sister chromatid segregation [Term] id: GO:0033046 name: negative regulation of sister chromatid segregation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation." [GOC:mah] is_a: GO:0033045 ! regulation of sister chromatid segregation is_a: GO:0051985 ! negative regulation of chromosome segregation is_a: GO:2001251 ! negative regulation of chromosome organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0000819 ! negatively regulates sister chromatid segregation relationship: RO:0002212 GO:0000819 ! negatively regulates sister chromatid segregation [Term] id: GO:0033047 name: regulation of mitotic sister chromatid segregation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of sister chromatid segregation during mitosis." [GOC:mah] is_a: GO:0033045 ! regulation of sister chromatid segregation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0000070 ! regulates (processual) mitotic sister chromatid segregation relationship: RO:0002211 GO:0000070 ! regulates (processual) mitotic sister chromatid segregation [Term] id: GO:0033048 name: negative regulation of mitotic sister chromatid segregation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation during mitosis." [GOC:mah] is_a: GO:0033046 ! negative regulation of sister chromatid segregation is_a: GO:0033047 ! regulation of mitotic sister chromatid segregation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0000070 ! negatively regulates mitotic sister chromatid segregation relationship: RO:0002212 GO:0000070 ! negatively regulates mitotic sister chromatid segregation [Term] id: GO:0033059 name: cellular pigmentation namespace: biological_process def: "The deposition or aggregation of coloring matter in a cell." [GOC:mtg_MIT_16mar07] is_a: GO:0009987 ! cellular process is_a: GO:0043473 ! pigmentation [Term] id: GO:0033157 name: regulation of intracellular protein transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells." [GOC:mah] is_a: GO:0032386 ! regulation of intracellular transport is_a: GO:0051223 ! regulation of protein transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006886 ! regulates (processual) intracellular protein transport relationship: RO:0002211 GO:0006886 ! regulates (processual) intracellular protein transport [Term] id: GO:0033238 name: regulation of amine metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform amines." [GOC:mah] synonym: "regulation of amine metabolism" EXACT [] synonym: "regulation of cellular amine metabolic process" EXACT [] is_a: GO:0051171 ! regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0009308 ! regulates (processual) amine metabolic process relationship: RO:0002211 GO:0009308 ! regulates (processual) amine metabolic process [Term] id: GO:0033239 name: negative regulation of amine metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amines." [GOC:mah] synonym: "negative regulation of amine metabolism" EXACT [] synonym: "negative regulation of cellular amine metabolic process" EXACT [] is_a: GO:0033238 ! regulation of amine metabolic process is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0009308 ! negatively regulates amine metabolic process relationship: RO:0002212 GO:0009308 ! negatively regulates amine metabolic process [Term] id: GO:0033240 name: positive regulation of amine metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amines." [GOC:mah] synonym: "positive regulation of amine metabolism" EXACT [] synonym: "positive regulation of cellular amine metabolic process" EXACT [] is_a: GO:0033238 ! regulation of amine metabolic process is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0009308 ! positively regulates amine metabolic process relationship: RO:0002213 GO:0009308 ! positively regulates amine metabolic process [Term] id: GO:0033241 name: regulation of amine catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines." [GOC:mah] synonym: "regulation of amine breakdown" EXACT [] synonym: "regulation of amine catabolism" EXACT [] synonym: "regulation of amine degradation" EXACT [] synonym: "regulation of cellular amine catabolic process" EXACT [] is_a: GO:0009894 ! regulation of catabolic process is_a: GO:0033238 ! regulation of amine metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0009310 ! regulates (processual) amine catabolic process relationship: RO:0002211 GO:0009310 ! regulates (processual) amine catabolic process [Term] id: GO:0033242 name: negative regulation of amine catabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines." [GOC:mah] synonym: "negative regulation of amine breakdown" EXACT [] synonym: "negative regulation of amine catabolism" EXACT [] synonym: "negative regulation of amine degradation" EXACT [] synonym: "negative regulation of cellular amine catabolic process" EXACT [] is_a: GO:0009895 ! negative regulation of catabolic process is_a: GO:0033239 ! negative regulation of amine metabolic process is_a: GO:0033241 ! regulation of amine catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0009310 ! negatively regulates amine catabolic process relationship: RO:0002212 GO:0009310 ! negatively regulates amine catabolic process [Term] id: GO:0033243 name: positive regulation of amine catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines." [GOC:mah] synonym: "positive regulation of amine breakdown" EXACT [] synonym: "positive regulation of amine catabolism" EXACT [] synonym: "positive regulation of amine degradation" EXACT [] is_a: GO:0009896 ! positive regulation of catabolic process is_a: GO:0033240 ! positive regulation of amine metabolic process is_a: GO:0033241 ! regulation of amine catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0009310 ! positively regulates amine catabolic process relationship: RO:0002213 GO:0009310 ! positively regulates amine catabolic process [Term] id: GO:0033278 name: cell proliferation in midbrain namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population in the midbrain." [GO_REF:0000021, GOC:dgf] synonym: "cell proliferation in mesencephalon" EXACT [] is_a: GO:0061351 ! neural precursor cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: BFO:0000066 UBERON:0001891 ! occurs in midbrain relationship: BFO:0000050 GO:0030901 ! part of midbrain development relationship: BFO:0000066 UBERON:0001891 ! occurs in midbrain [Term] id: GO:0033363 name: secretory granule organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion." [GOC:mah] synonym: "secretory granule organisation" EXACT [GOC:mah] is_a: GO:0016050 ! vesicle organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0030141 ! results in organization of secretory granule relationship: BFO:0000050 GO:0010256 ! part of endomembrane system organization relationship: RO:0002592 GO:0030141 ! results in organization of secretory granule [Term] id: GO:0033365 name: protein localization to organelle namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within an organelle." [GOC:mah] synonym: "protein localisation to organelle" EXACT [GOC:mah] synonym: "protein localization in organelle" EXACT [GOC:mah] is_a: GO:0008104 ! protein localization intersection_of: GO:0008104 ! protein localization intersection_of: RO:0002339 GO:0043226 ! has target end location organelle relationship: RO:0002339 GO:0043226 ! has target end location organelle [Term] id: GO:0033366 name: protein localization to secretory granule namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within a secretory granule." [GOC:mah] synonym: "protein localisation in secretory granule" EXACT [GOC:mah] synonym: "protein localization in secretory granule" EXACT [] is_a: GO:0033365 ! protein localization to organelle intersection_of: GO:0008104 ! protein localization intersection_of: RO:0002339 GO:0030141 ! has target end location secretory granule relationship: RO:0002339 GO:0030141 ! has target end location secretory granule [Term] id: GO:0033371 name: T cell secretory granule organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a T cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion." [GOC:mah] synonym: "T cell secretory granule organisation" EXACT [GOC:mah] synonym: "T lymphocyte secretory granule organization" EXACT [] synonym: "T-cell secretory granule organization" EXACT [] synonym: "T-lymphocyte secretory granule organization" EXACT [] is_a: GO:0033363 ! secretory granule organization intersection_of: GO:0016043 ! cellular component organization intersection_of: BFO:0000066 CL:0000084 ! occurs in T cell intersection_of: RO:0002592 GO:0030141 ! results in organization of secretory granule relationship: BFO:0000066 CL:0000084 ! occurs in T cell [Term] id: GO:0033604 name: negative regulation of catecholamine secretion namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a catecholamine." [GOC:mah] synonym: "down regulation of catecholamine secretion" EXACT [] synonym: "down-regulation of catecholamine secretion" EXACT [] synonym: "downregulation of catecholamine secretion" EXACT [] is_a: GO:0050433 ! regulation of catecholamine secretion is_a: GO:0051953 ! negative regulation of amine transport is_a: GO:1903531 ! negative regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0050432 ! negatively regulates catecholamine secretion relationship: RO:0002212 GO:0050432 ! negatively regulates catecholamine secretion [Term] id: GO:0033605 name: positive regulation of catecholamine secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of a catecholamine." [GOC:mah] synonym: "up regulation of catecholamine secretion" EXACT [] synonym: "up-regulation of catecholamine secretion" EXACT [] synonym: "upregulation of catecholamine secretion" EXACT [] is_a: GO:0050433 ! regulation of catecholamine secretion is_a: GO:0051954 ! positive regulation of amine transport is_a: GO:1903532 ! positive regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0050432 ! positively regulates catecholamine secretion relationship: RO:0002213 GO:0050432 ! positively regulates catecholamine secretion [Term] id: GO:0033673 name: negative regulation of kinase activity namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." [GOC:mah] synonym: "down regulation of kinase activity" EXACT [] synonym: "down-regulation of kinase activity" EXACT [] synonym: "downregulation of kinase activity" EXACT [] is_a: GO:0042326 ! negative regulation of phosphorylation is_a: GO:0043549 ! regulation of kinase activity is_a: GO:0051348 ! negative regulation of transferase activity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0016301 ! negatively regulates kinase activity relationship: RO:0002212 GO:0016301 ! negatively regulates kinase activity [Term] id: GO:0033674 name: positive regulation of kinase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." [GOC:mah] synonym: "up regulation of kinase activity" EXACT [] synonym: "up-regulation of kinase activity" EXACT [] synonym: "upregulation of kinase activity" EXACT [] is_a: GO:0042327 ! positive regulation of phosphorylation is_a: GO:0043549 ! regulation of kinase activity is_a: GO:0051347 ! positive regulation of transferase activity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0016301 ! positively regulates kinase activity relationship: RO:0002213 GO:0016301 ! positively regulates kinase activity [Term] id: GO:0033750 name: ribosome localization namespace: biological_process def: "A process in which a ribosome is transported to, and/or maintained in, a specific location." [GOC:mah] is_a: GO:0051640 ! organelle localization intersection_of: GO:0051179 ! localization intersection_of: RO:0004009 GO:0005840 ! has primary input ribosome relationship: RO:0004009 GO:0005840 ! has primary input ribosome [Term] id: GO:0033762 name: response to glucagon namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus." [GOC:sl] synonym: "response to glucagon stimulus" EXACT [GOC:dos] is_a: GO:0043434 ! response to peptide hormone intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:5391 ! has primary input glucagon relationship: RO:0004009 CHEBI:5391 ! has primary input glucagon [Term] id: GO:0033993 name: response to lipid namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus." [GOC:sl] is_a: GO:0010033 ! response to organic substance intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:18059 ! has primary input lipid relationship: RO:0004009 CHEBI:18059 ! has primary input lipid [Term] id: GO:0034067 name: protein localization to Golgi apparatus namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within the Golgi apparatus." [GOC:mah] synonym: "protein localisation in Golgi apparatus" EXACT [GOC:mah] synonym: "protein localization in Golgi apparatus" EXACT [] is_a: GO:0033365 ! protein localization to organelle intersection_of: GO:0008104 ! protein localization intersection_of: RO:0002339 GO:0005794 ! has target end location Golgi apparatus relationship: RO:0002339 GO:0005794 ! has target end location Golgi apparatus creation_date: 2011-02-14T02:26:36Z [Term] id: GO:0034101 name: erythrocyte homeostasis namespace: biological_process def: "Any process of regulating the production and elimination of erythrocytes within an organism." [GOC:add, PMID:10694114, PMID:14754397] synonym: "RBC homeostasis" EXACT [CL:0000232] synonym: "red blood cell homeostasis" EXACT [CL:0000232] is_a: GO:0002262 ! myeloid cell homeostasis intersection_of: GO:0048872 ! homeostasis of number of cells intersection_of: RO:0012003 CL:0000232 ! acts on population of erythrocyte relationship: RO:0012003 CL:0000232 ! acts on population of erythrocyte [Term] id: GO:0034219 name: carbohydrate transmembrane transport namespace: biological_process def: "The process in which a carbohydrate is transported across a membrane." [GOC:mah] synonym: "carbohydrate membrane transport" EXACT [] synonym: "transmembrane carbohydrate transport" EXACT [GOC:dph, GOC:tb] is_a: GO:0008643 ! carbohydrate transport is_a: GO:0055085 ! transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002342 GO:0016020 ! results in transport across membrane intersection_of: RO:0004009 CHEBI:16646 ! has primary input carbohydrate [Term] id: GO:0034220 name: monoatomic ion transmembrane transport namespace: biological_process def: "A process in which a monoatomic ion is transported across a membrane. Monatomic ions (also called simple ions) are ions consisting of exactly one atom." [GOC:mah] synonym: "ion membrane transport" EXACT [] synonym: "transmembrane ion transport" EXACT [GOC:dph, GOC:tb] is_a: GO:0006811 ! monoatomic ion transport is_a: GO:0055085 ! transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002342 GO:0016020 ! results in transport across membrane intersection_of: RO:0004009 CHEBI:24867 ! has primary input monoatomic ion [Term] id: GO:0034242 name: negative regulation of syncytium formation by plasma membrane fusion namespace: biological_process def: "Any process that decreases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." [GOC:mah] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051129 ! negative regulation of cellular component organization is_a: GO:0060142 ! regulation of syncytium formation by plasma membrane fusion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0000768 ! negatively regulates syncytium formation by plasma membrane fusion relationship: RO:0002212 GO:0000768 ! negatively regulates syncytium formation by plasma membrane fusion [Term] id: GO:0034248 name: regulation of amide metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amides." [GOC:mah] synonym: "regulation of amide metabolism" EXACT [] synonym: "regulation of cellular amide metabolic process" EXACT [] is_a: GO:0051171 ! regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0043603 ! regulates (processual) amide metabolic process relationship: RO:0002211 GO:0043603 ! regulates (processual) amide metabolic process [Term] id: GO:0034249 name: negative regulation of amide metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amides." [GOC:mah] synonym: "negative regulation of amide metabolism" EXACT [] synonym: "negative regulation of cellular amide metabolic process" EXACT [] is_a: GO:0034248 ! regulation of amide metabolic process is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0043603 ! negatively regulates amide metabolic process relationship: RO:0002212 GO:0043603 ! negatively regulates amide metabolic process [Term] id: GO:0034250 name: positive regulation of amide metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amides." [GOC:mah] synonym: "positive regulation of amide metabolism" EXACT [] synonym: "positive regulation of cellular amide metabolic process" EXACT [] is_a: GO:0034248 ! regulation of amide metabolic process is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0043603 ! positively regulates amide metabolic process relationship: RO:0002213 GO:0043603 ! positively regulates amide metabolic process [Term] id: GO:0034251 name: regulation of amide catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides." [GOC:mah] synonym: "regulation of amide breakdown" EXACT [] synonym: "regulation of amide catabolism" EXACT [] synonym: "regulation of amide degradation" EXACT [] synonym: "regulation of cellular amide catabolic process" EXACT [] is_a: GO:0009894 ! regulation of catabolic process is_a: GO:0034248 ! regulation of amide metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0043605 ! regulates (processual) amide catabolic process relationship: RO:0002211 GO:0043605 ! regulates (processual) amide catabolic process [Term] id: GO:0034252 name: negative regulation of amide catabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides." [GOC:mah] synonym: "negative regulation of amide breakdown" EXACT [] synonym: "negative regulation of amide catabolism" EXACT [] synonym: "negative regulation of cellular amide catabolic process" EXACT [] is_a: GO:0009895 ! negative regulation of catabolic process is_a: GO:0034249 ! negative regulation of amide metabolic process is_a: GO:0034251 ! regulation of amide catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0043605 ! negatively regulates amide catabolic process relationship: RO:0002212 GO:0043605 ! negatively regulates amide catabolic process [Term] id: GO:0034253 name: positive regulation of amide catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides." [GOC:mah] synonym: "positive regulation of amide breakdown" EXACT [] synonym: "positive regulation of amide catabolism" EXACT [] synonym: "positive regulation of cellular amide catabolic process" EXACT [] is_a: GO:0009896 ! positive regulation of catabolic process is_a: GO:0034250 ! positive regulation of amide metabolic process is_a: GO:0034251 ! regulation of amide catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0043605 ! positively regulates amide catabolic process relationship: RO:0002213 GO:0043605 ! positively regulates amide catabolic process [Term] id: GO:0034284 name: response to monosaccharide namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus." [GOC:mah] synonym: "response to monosaccharide stimulus" EXACT [GOC:dos] is_a: GO:0009743 ! response to carbohydrate intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:35381 ! has primary input monosaccharide relationship: RO:0004009 CHEBI:35381 ! has primary input monosaccharide [Term] id: GO:0034329 name: cell junction assembly namespace: biological_process def: "A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a cell junction." [GOC:mah] is_a: GO:0022607 ! cellular component assembly is_a: GO:0034330 ! cell junction organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0030054 ! results in assembly of cell junction relationship: RO:0002588 GO:0030054 ! results in assembly of cell junction [Term] id: GO:0034330 name: cell junction organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell junction. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix." [GOC:dph, GOC:jl, GOC:mah] synonym: "cell junction assembly and maintenance" EXACT [] synonym: "cell junction organisation" EXACT [GOC:mah] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0030054 ! results in organization of cell junction relationship: RO:0002592 GO:0030054 ! results in organization of cell junction [Term] id: GO:0034349 name: glial cell apoptotic process namespace: biological_process def: "Any apoptotic process in a glial cell, a non-neuronal cell of the nervous system." [CL:0000125, GOC:mtg_apoptosis, GOC:sart] synonym: "apoptosis of glia" EXACT [] synonym: "apoptosis of glial cells" EXACT [] synonym: "glia apoptosis" EXACT [] synonym: "glia programmed cell death by apoptosis" EXACT [] synonym: "glial cell programmed cell death by apoptosis" EXACT [] synonym: "programmed cell death of glia by apoptosis" EXACT [] synonym: "programmed cell death of glial cells by apoptosis" EXACT [] synonym: "programmed cell death, glia" EXACT [] synonym: "programmed cell death, glial cells" EXACT [] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000125 ! occurs in glial cell relationship: BFO:0000066 CL:0000125 ! occurs in glial cell [Term] id: GO:0034350 name: regulation of glial cell apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of glial cell apoptotic process." [GOC:mah, GOC:mtg_apoptosis] is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0034349 ! regulates (processual) glial cell apoptotic process relationship: RO:0002211 GO:0034349 ! regulates (processual) glial cell apoptotic process [Term] id: GO:0034351 name: negative regulation of glial cell apoptotic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of glial cell apoptotic process." [GOC:mah, GOC:mtg_apoptosis] synonym: "down regulation of glial cell apoptosis" EXACT [] synonym: "down-regulation of glial cell apoptosis" EXACT [] synonym: "downregulation of glial cell apoptosis" EXACT [] is_a: GO:0034350 ! regulation of glial cell apoptotic process is_a: GO:0043066 ! negative regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0034349 ! negatively regulates glial cell apoptotic process relationship: RO:0002212 GO:0034349 ! negatively regulates glial cell apoptotic process [Term] id: GO:0034352 name: positive regulation of glial cell apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of glial cell apoptotic process." [GOC:mah, GOC:mtg_apoptosis] synonym: "up regulation of glial cell apoptosis" EXACT [] synonym: "up-regulation of glial cell apoptosis" EXACT [] synonym: "upregulation of glial cell apoptosis" EXACT [] is_a: GO:0034350 ! regulation of glial cell apoptotic process is_a: GO:0043065 ! positive regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0034349 ! positively regulates glial cell apoptotic process relationship: RO:0002213 GO:0034349 ! positively regulates glial cell apoptotic process [Term] id: GO:0034390 name: smooth muscle cell apoptotic process namespace: biological_process def: "Any apoptotic process in a smooth muscle cell. Smooth muscle consists of non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels." [CL:0000192, GOC:BHF, GOC:mah, GOC:mtg_apoptosis, GOC:rl] synonym: "apoptosis of smooth muscle cells" EXACT [] synonym: "programmed cell death of smooth muscle cells by apoptosis" EXACT [] synonym: "programmed cell death, smooth muscle cells" EXACT [] synonym: "SMC apoptosis" EXACT [] synonym: "smooth muscle cell programmed cell death by apoptosis" EXACT [] is_a: GO:0010657 ! muscle cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000192 ! occurs in smooth muscle cell relationship: BFO:0000066 CL:0000192 ! occurs in smooth muscle cell [Term] id: GO:0034391 name: regulation of smooth muscle cell apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of smooth muscle cell apoptotic process." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl] synonym: "regulation of SMC apoptosis" EXACT [] is_a: GO:0010660 ! regulation of muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0034390 ! regulates (processual) smooth muscle cell apoptotic process relationship: RO:0002211 GO:0034390 ! regulates (processual) smooth muscle cell apoptotic process [Term] id: GO:0034392 name: negative regulation of smooth muscle cell apoptotic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell apoptotic process." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl] synonym: "down regulation of smooth muscle cell apoptosis" EXACT [] synonym: "down-regulation of smooth muscle cell apoptosis" EXACT [] synonym: "downregulation of smooth muscle cell apoptosis" EXACT [] synonym: "negative regulation of SMC apoptosis" EXACT [] is_a: GO:0010656 ! negative regulation of muscle cell apoptotic process is_a: GO:0034391 ! regulation of smooth muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0034390 ! negatively regulates smooth muscle cell apoptotic process relationship: RO:0002212 GO:0034390 ! negatively regulates smooth muscle cell apoptotic process [Term] id: GO:0034393 name: positive regulation of smooth muscle cell apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of smooth muscle cell apoptotic process." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl] synonym: "positive regulation of SMC apoptosis" EXACT [] synonym: "up regulation of smooth muscle cell apoptosis" EXACT [] synonym: "up-regulation of smooth muscle cell apoptosis" EXACT [] synonym: "upregulation of smooth muscle cell apoptosis" EXACT [] is_a: GO:0010661 ! positive regulation of muscle cell apoptotic process is_a: GO:0034391 ! regulation of smooth muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0034390 ! positively regulates smooth muscle cell apoptotic process relationship: RO:0002213 GO:0034390 ! positively regulates smooth muscle cell apoptotic process [Term] id: GO:0034436 name: glycoprotein transport namespace: biological_process def: "The directed movement of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:BHF, GOC:mah, GOC:rl] is_a: GO:0045184 ! establishment of protein localization is_a: GO:1901264 ! carbohydrate derivative transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:17089 ! has primary input glycoprotein relationship: RO:0004009 CHEBI:17089 ! has primary input glycoprotein [Term] id: GO:0034486 name: vacuolar transmembrane transport namespace: biological_process def: "The process in which a solute is transported from one side of the vacuolar membrane to the other." [GOC:mah] synonym: "vacuolar membrane transport" EXACT [] is_a: GO:0055085 ! transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002342 GO:0016020 ! results in transport across membrane intersection_of: RO:0002344 GO:0005773 ! results in transport to from or in vacuole relationship: RO:0002344 GO:0005773 ! results in transport to from or in vacuole [Term] id: GO:0034487 name: vacuolar amino acid transmembrane transport namespace: biological_process def: "The process in which an amino acid is transported from one side of the vacuolar membrane to the other." [GOC:mah] synonym: "vacuolar amino acid membrane transport" EXACT [] is_a: GO:0003333 ! amino acid transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002342 GO:0005774 ! results in transport across vacuolar membrane intersection_of: RO:0004009 CHEBI:33709 ! has primary input amino acid relationship: RO:0002342 GO:0005774 ! results in transport across vacuolar membrane [Term] id: GO:0034502 name: protein localization to chromosome namespace: biological_process def: "Any process in which a protein is transported to, or maintained at, a specific location on a chromosome." [GOC:mah] synonym: "protein localisation to chromosome" EXACT [GOC:mah] is_a: GO:0033365 ! protein localization to organelle intersection_of: GO:0008104 ! protein localization intersection_of: RO:0002339 GO:0005694 ! has target end location chromosome relationship: RO:0002339 GO:0005694 ! has target end location chromosome [Term] id: GO:0034504 name: protein localization to nucleus namespace: biological_process def: "A process in which a protein transports or maintains the localization of another protein to the nucleus." [GOC:ecd] synonym: "protein localisation to nucleus" EXACT [GOC:mah] synonym: "protein localization in cell nucleus" EXACT [] synonym: "protein localization in nucleus" EXACT [GOC:mah] is_a: GO:0033365 ! protein localization to organelle intersection_of: GO:0008104 ! protein localization intersection_of: RO:0002339 GO:0005634 ! has target end location nucleus relationship: RO:0002339 GO:0005634 ! has target end location nucleus creation_date: 2012-11-07T15:45:54Z [Term] id: GO:0034641 name: cellular nitrogen compound metabolic process namespace: biological_process def: "The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells." [GOC:mah] synonym: "cellular nitrogen compound metabolism" EXACT [] is_a: GO:0006807 ! nitrogen compound metabolic process is_a: GO:0044237 ! cellular metabolic process [Term] id: GO:0034654 name: nucleobase-containing compound biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:mah] synonym: "nucleobase, nucleoside, nucleotide and nucleic acid anabolism" EXACT [] synonym: "nucleobase, nucleoside, nucleotide and nucleic acid biosynthesis" EXACT [] synonym: "nucleobase, nucleoside, nucleotide and nucleic acid formation" EXACT [] is_a: GO:0006139 ! nucleobase-containing compound metabolic process is_a: GO:0018130 ! heterocycle biosynthetic process is_a: GO:0019438 ! aromatic compound biosynthetic process is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process is_a: GO:1901362 ! organic cyclic compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:61120 ! has primary output nucleobase-containing molecular entity relationship: RO:0004008 CHEBI:61120 ! has primary output nucleobase-containing molecular entity [Term] id: GO:0034655 name: nucleobase-containing compound catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:mah] synonym: "nucleobase, nucleoside, nucleotide and nucleic acid breakdown" EXACT [] synonym: "nucleobase, nucleoside, nucleotide and nucleic acid catabolism" EXACT [] synonym: "nucleobase, nucleoside, nucleotide and nucleic acid degradation" EXACT [] is_a: GO:0006139 ! nucleobase-containing compound metabolic process is_a: GO:0019439 ! aromatic compound catabolic process is_a: GO:0044270 ! cellular nitrogen compound catabolic process is_a: GO:0046700 ! heterocycle catabolic process is_a: GO:1901361 ! organic cyclic compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:61120 ! has primary input nucleobase-containing molecular entity relationship: RO:0004009 CHEBI:61120 ! has primary input nucleobase-containing molecular entity [Term] id: GO:0034672 name: anterior/posterior pattern specification involved in pronephros development namespace: biological_process def: "The developmental process that results in the creation of defined areas or spaces within the pronephros along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate." [GOC:mah] synonym: "anterior/posterior pattern specification involved in pronephric kidney development" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0039017 ! pattern specification involved in pronephros development is_a: GO:0072098 ! anterior/posterior pattern specification involved in kidney development intersection_of: GO:0009952 ! anterior/posterior pattern specification intersection_of: BFO:0000050 GO:0048793 ! part of pronephros development [Term] id: GO:0034762 name: regulation of transmembrane transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other." [GOC:mah] synonym: "regulation of membrane transport" EXACT [] is_a: GO:0050794 ! regulation of cellular process is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0055085 ! regulates (processual) transmembrane transport relationship: RO:0002211 GO:0055085 ! regulates (processual) transmembrane transport [Term] id: GO:0034763 name: negative regulation of transmembrane transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other." [GOC:mah] synonym: "down regulation of transmembrane transport" EXACT [] synonym: "down-regulation of transmembrane transport" EXACT [] synonym: "downregulation of transmembrane transport" EXACT [] synonym: "negative regulation of membrane transport" EXACT [] is_a: GO:0034762 ! regulation of transmembrane transport is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:0051051 ! negative regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0055085 ! negatively regulates transmembrane transport relationship: RO:0002212 GO:0055085 ! negatively regulates transmembrane transport [Term] id: GO:0034764 name: positive regulation of transmembrane transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other." [GOC:mah] synonym: "positive regulation of membrane transport" EXACT [] synonym: "up regulation of transmembrane transport" EXACT [] synonym: "up-regulation of transmembrane transport" EXACT [] synonym: "upregulation of transmembrane transport" EXACT [] is_a: GO:0034762 ! regulation of transmembrane transport is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:0051050 ! positive regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0055085 ! positively regulates transmembrane transport relationship: RO:0002213 GO:0055085 ! positively regulates transmembrane transport [Term] id: GO:0034765 name: regulation of monoatomic ion transmembrane transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other." [GOC:mah] synonym: "regulation of ion membrane transport" EXACT [] synonym: "regulation of transmembrane ion transport" EXACT [GOC:dph, GOC:tb] is_a: GO:0034762 ! regulation of transmembrane transport is_a: GO:0043269 ! regulation of monoatomic ion transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0034220 ! regulates (processual) monoatomic ion transmembrane transport relationship: RO:0002211 GO:0034220 ! regulates (processual) monoatomic ion transmembrane transport [Term] id: GO:0034766 name: negative regulation of monoatomic ion transmembrane transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other." [GOC:mah] synonym: "down regulation of transmembrane ion transport" EXACT [] synonym: "down-regulation of transmembrane ion transport" EXACT [] synonym: "downregulation of transmembrane ion transport" EXACT [] synonym: "negative regulation of ion membrane transport" EXACT [] synonym: "negative regulation of transmembrane ion transport" EXACT [GOC:dph, GOC:tb] is_a: GO:0034763 ! negative regulation of transmembrane transport is_a: GO:0034765 ! regulation of monoatomic ion transmembrane transport is_a: GO:0043271 ! negative regulation of monoatomic ion transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0034220 ! negatively regulates monoatomic ion transmembrane transport relationship: RO:0002212 GO:0034220 ! negatively regulates monoatomic ion transmembrane transport [Term] id: GO:0034767 name: positive regulation of monoatomic ion transmembrane transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other." [GOC:mah] synonym: "positive regulation of ion membrane transport" EXACT [] synonym: "positive regulation of transmembrane ion transport" EXACT [] synonym: "up regulation of transmembrane ion transport" EXACT [] synonym: "up-regulation of transmembrane ion transport" EXACT [] synonym: "upregulation of transmembrane ion transport" EXACT [] is_a: GO:0034764 ! positive regulation of transmembrane transport is_a: GO:0034765 ! regulation of monoatomic ion transmembrane transport is_a: GO:0043270 ! positive regulation of monoatomic ion transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0034220 ! positively regulates monoatomic ion transmembrane transport relationship: RO:0002213 GO:0034220 ! positively regulates monoatomic ion transmembrane transport [Term] id: GO:0034769 name: basement membrane disassembly namespace: biological_process def: "The controlled breakdown of the basement membrane in the context of a normal process such as imaginal disc eversion." [GOC:sart, PMID:17301221] is_a: GO:0022617 ! extracellular matrix disassembly is_a: GO:0071711 ! basement membrane organization intersection_of: GO:0022411 ! cellular component disassembly intersection_of: RO:0002590 GO:0005604 ! results in disassembly of basement membrane relationship: RO:0002590 GO:0005604 ! results in disassembly of basement membrane creation_date: 2009-08-13T11:27:24Z [Term] id: GO:0035019 name: somatic stem cell population maintenance namespace: biological_process def: "Any process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line." [GOC:bf, ISBN:0582227089] is_a: GO:0019827 ! stem cell population maintenance intersection_of: GO:0098727 ! maintenance of cell number intersection_of: RO:0012003 CL:0000723 ! acts on population of somatic stem cell relationship: RO:0012003 CL:0000723 ! acts on population of somatic stem cell [Term] id: GO:0035039 name: male pronucleus assembly namespace: biological_process def: "The conversion at fertilization of the inactive sperm nucleus into a male pronucleus with its chromosomes processed for the first zygotic division." [GOC:bf, PMID:11735001] is_a: GO:0006997 ! nucleus organization is_a: GO:0022414 ! reproductive process is_a: GO:0070925 ! organelle assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0001940 ! results in assembly of male pronucleus relationship: BFO:0000050 GO:0007338 ! part of single fertilization relationship: RO:0002588 GO:0001940 ! results in assembly of male pronucleus [Term] id: GO:0035040 name: sperm nuclear envelope removal namespace: biological_process def: "Removal of the sperm nuclear envelope, allowing entry of maternal factors into the sperm nucleus." [GOC:bf, PMID:11735001] is_a: GO:0022414 ! reproductive process is_a: GO:0051081 ! nuclear membrane disassembly intersection_of: GO:0051081 ! nuclear membrane disassembly intersection_of: BFO:0000066 CL:0000019 ! occurs in sperm relationship: BFO:0000050 GO:0035039 ! part of male pronucleus assembly relationship: BFO:0000066 CL:0000019 ! occurs in sperm [Term] id: GO:0035045 name: sperm plasma membrane disassembly namespace: biological_process def: "The gradual disintegration of the sperm plasma membrane following insemination. This process is seen in Drosophila after entry of the entire sperm, surrounded by its plasma membrane, into the egg." [GOC:bf, ISBN:0879694238] synonym: "sperm plasma membrane breakdown" EXACT [] synonym: "sperm plasma membrane catabolism" EXACT [] synonym: "sperm plasma membrane degradation" EXACT [] is_a: GO:0007009 ! plasma membrane organization is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0030397 ! membrane disassembly intersection_of: GO:0022411 ! cellular component disassembly intersection_of: RO:0002590 GO:0097524 ! results in disassembly of sperm plasma membrane relationship: BFO:0000050 GO:0007338 ! part of single fertilization relationship: RO:0002590 GO:0097524 ! results in disassembly of sperm plasma membrane [Term] id: GO:0035050 name: embryonic heart tube development namespace: biological_process def: "The process whose specific outcome is the progression of the embryonic heart tube over time, from its formation to the mature structure. The heart tube forms as the heart rudiment from the heart field." [GOC:go_curators] is_a: GO:0035295 ! tube development is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004141 ! results in development of heart tube relationship: BFO:0000050 GO:0007507 ! part of heart development relationship: BFO:0000050 GO:0048568 ! part of embryonic organ development relationship: RO:0002296 UBERON:0004141 ! results in development of heart tube [Term] id: GO:0035051 name: cardiocyte differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell that will form part of the cardiac organ of an individual." [GOC:bf] synonym: "cardiac cell differentiation" EXACT [] synonym: "heart cell differentiation" EXACT [] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0002494 ! results in acquisition of features of cardiocyte relationship: BFO:0000050 GO:0007507 ! part of heart development relationship: RO:0002315 CL:0002494 ! results in acquisition of features of cardiocyte [Term] id: GO:0035082 name: axoneme assembly namespace: biological_process def: "The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements." [GOC:bf, GOC:cilia, GOC:jl, ISBN:0815316194] synonym: "ciliary axoneme assembly" EXACT [] synonym: "cilium axoneme assembly" EXACT [] synonym: "flagellar axoneme assembly" EXACT [] synonym: "flagellum axoneme assembly" EXACT [] is_a: GO:0001578 ! microtubule bundle formation is_a: GO:0022607 ! cellular component assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0005930 ! results in assembly of axoneme relationship: BFO:0000050 GO:0060271 ! part of cilium assembly relationship: RO:0002588 GO:0005930 ! results in assembly of axoneme [Term] id: GO:0035107 name: appendage morphogenesis namespace: biological_process def: "The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch." [ISBN:0582227089] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000026 ! results in morphogenesis of appendage relationship: BFO:0000050 GO:0048736 ! part of appendage development relationship: RO:0002298 UBERON:0000026 ! results in morphogenesis of appendage [Term] id: GO:0035112 name: genitalia morphogenesis namespace: biological_process def: "The process in which the anatomical structures of genitalia are generated and organized. The genitalia are the organs of reproduction or generation, external and internal." [GOC:bf] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000990 ! results in morphogenesis of reproductive system relationship: BFO:0000050 GO:0048806 ! part of genitalia development relationship: RO:0002298 UBERON:0000990 ! results in morphogenesis of reproductive system [Term] id: GO:0035148 name: tube formation namespace: biological_process def: "Creation of the central hole of a tube in an anatomical structure through which gases and/or liquids flow." [GOC:bf] synonym: "tube lumen formation" EXACT [GOC:dph, GOC:mah] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0000025 ! results in formation of anatomical entity tube relationship: BFO:0000050 GO:0035239 ! part of tube morphogenesis relationship: RO:0002297 UBERON:0000025 ! results in formation of anatomical entity tube [Term] id: GO:0035190 name: syncytial nuclear migration namespace: biological_process def: "The directed movement of nuclei within the syncytial embryo of insects. These precise temporal and spatial patterns of nuclear movement are coordinated with mitotic divisons and are required during blastoderm formation to reposition dividing nuclei from the interior of the syncytial embryo to the cortex." [GOC:bf, ISBN:0879694238, PMID:8314839] is_a: GO:0007097 ! nuclear migration intersection_of: GO:0007097 ! nuclear migration intersection_of: BFO:0000066 CL:0000228 ! occurs in multinucleate cell relationship: BFO:0000050 GO:0001700 ! part of embryonic development via the syncytial blastoderm relationship: BFO:0000066 CL:0000228 ! occurs in multinucleate cell [Term] id: GO:0035209 name: pupal development namespace: biological_process def: "The process whose specific outcome is the progression of the pupa over time, from its formation to the mature structure. The pupa is a dormant life stage interposed between the larval and the adult stages in insects that undergo a complete metamorphosis." [GOC:bf, GOC:mtg_sensu] is_a: GO:0002165 ! instar larval or pupal development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003143 ! results in development of pupa relationship: RO:0002224 GO:0018989 ! starts with apolysis relationship: RO:0002230 GO:0007562 ! ends with eclosion relationship: RO:0002296 UBERON:0003143 ! results in development of pupa [Term] id: GO:0035234 name: ectopic germ cell programmed cell death namespace: biological_process def: "Programmed cell death of an errant germ line cell that is outside the normal migratory path or ectopic to the gonad. This is an important mechanism of regulating germ cell survival within the embryo." [PMID:12814944] synonym: "programmed cell death of ectopic germ cells" EXACT [] synonym: "programmed cell death, ectopic germ cells" EXACT [] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0010623 ! programmed cell death involved in cell development intersection_of: GO:0012501 ! programmed cell death intersection_of: BFO:0000066 CL:0000586 ! occurs in germ cell relationship: BFO:0000066 CL:0000586 ! occurs in germ cell [Term] id: GO:0035239 name: tube morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a tube are generated and organized. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system." [GOC:bf, PMID:14624839] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000025 ! results in morphogenesis of tube relationship: BFO:0000050 GO:0035295 ! part of tube development relationship: RO:0002298 UBERON:0000025 ! results in morphogenesis of tube [Term] id: GO:0035260 name: internal genitalia morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the internal genitalia are generated and organized. The internal genitalia are the internal sex organs such as the uterine tube, the uterus and the vagina in female mammals, and the testis, seminal vesicle, ejaculatory duct and prostate in male mammals." [http://www.ndif.org/Terms/genitalia.html] is_a: GO:0035112 ! genitalia morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0004175 ! results in morphogenesis of internal genitalia relationship: RO:0002298 UBERON:0004175 ! results in morphogenesis of internal genitalia [Term] id: GO:0035261 name: external genitalia morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the external genitalia are generated and organized. The external genitalia are the outer sex organs, such as the penis or vulva in mammals." [http://www.ndif.org/Terms/genitalia.html] is_a: GO:0035112 ! genitalia morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0004176 ! results in morphogenesis of external genitalia relationship: RO:0002298 UBERON:0004176 ! results in morphogenesis of external genitalia [Term] id: GO:0035262 name: gonad morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the gonads are generated and organized. A gonad is an animal organ producing gametes, e.g. the testes or the ovary in mammals." [ISBN:0198612001] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000991 ! results in morphogenesis of gonad relationship: BFO:0000050 GO:0008406 ! part of gonad development relationship: RO:0002298 UBERON:0000991 ! results in morphogenesis of gonad [Term] id: GO:0035264 name: multicellular organism growth namespace: biological_process def: "The increase in size or mass of an entire multicellular organism, as opposed to cell growth." [GOC:bf, GOC:curators, GOC:dph, GOC:tb] is_a: GO:0032501 ! multicellular organismal process is_a: GO:0048589 ! developmental growth intersection_of: GO:0048589 ! developmental growth intersection_of: RO:0002343 UBERON:0000468 ! results in growth of multicellular organism relationship: RO:0002343 UBERON:0000468 ! results in growth of multicellular organism [Term] id: GO:0035265 name: organ growth namespace: biological_process def: "The increase in size or mass of an organ. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that function together as to perform a specific function." [GOC:bf, ISBN:0471245208, ISBN:0721662544] is_a: GO:0032501 ! multicellular organismal process is_a: GO:0048589 ! developmental growth intersection_of: GO:0048589 ! developmental growth intersection_of: RO:0002343 UBERON:0000062 ! results in growth of organ relationship: RO:0002343 UBERON:0000062 ! results in growth of organ [Term] id: GO:0035270 name: endocrine system development namespace: biological_process def: "Progression of the endocrine system over time, from its formation to a mature structure. The endocrine system is a system of hormones and ductless glands, where the glands release hormones directly into the blood, lymph or other intercellular fluid, and the hormones circulate within the body to affect distant organs. The major glands that make up the human endocrine system are the hypothalamus, pituitary, thyroid, parathryoids, adrenals, pineal body, and the reproductive glands which include the ovaries and testes." [GOC:bf, Wikipedia:Development_of_the_endocrine_system] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000949 ! results in development of endocrine system relationship: RO:0002296 UBERON:0000949 ! results in development of endocrine system [Term] id: GO:0035272 name: exocrine system development namespace: biological_process def: "Progression of the exocrine system over time, from its formation to a mature structure. The exocrine system is a system of hormones and glands, where the glands secrete straight to a target site via ducts or tubes. The human exocrine system includes the salivary glands, sweat glands and many glands of the digestive system." [GOC:bf, Wikipedia:Exocrine_gland] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002330 ! results in development of exocrine system relationship: RO:0002296 UBERON:0002330 ! results in development of exocrine system [Term] id: GO:0035282 name: segmentation namespace: biological_process def: "The regionalization process that divides an organism or part of an organism into a series of semi-repetitive parts, or segments, often arranged along a longitudinal axis." [PMID:10611687, PMID:9706689] xref: Wikipedia:Segmentation_(biology) is_a: GO:0003002 ! regionalization [Term] id: GO:0035290 name: trunk segmentation namespace: biological_process def: "Partitioning of the blastoderm embryo into trunk segmental units. In Drosophila, the trunk segments include thoracic segments and abdominal segments A1 to A8." [PMID:1360402] is_a: GO:0035282 ! segmentation relationship: BFO:0000050 GO:0007350 ! part of blastoderm segmentation [Term] id: GO:0035295 name: tube development namespace: biological_process def: "The process whose specific outcome is the progression of a tube over time, from its initial formation to a mature structure. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues including lung and trachea, kidney, the mammary gland, the vascular system and the gastrointestinal and urinary-genital tracts." [PMID:12526790] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000025 ! results in development of tube relationship: BFO:0000050 GO:0007275 ! part of multicellular organism development relationship: RO:0002296 UBERON:0000025 ! results in development of tube [Term] id: GO:0035372 name: protein localization to microtubule namespace: biological_process def: "A process in which a protein is transported to, or maintained at, a microtubule." [GOC:bf, GOC:lb] synonym: "protein localisation to microtubule" EXACT [GOC:mah] is_a: GO:0072698 ! protein localization to microtubule cytoskeleton intersection_of: GO:0008104 ! protein localization intersection_of: RO:0002339 GO:0005874 ! has target end location microtubule relationship: RO:0002339 GO:0005874 ! has target end location microtubule creation_date: 2010-03-11T11:00:56Z [Term] id: GO:0035418 name: protein localization to synapse namespace: biological_process def: "Any process in which a protein is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell." [GOC:bf] synonym: "protein localisation to synapse" EXACT [GOC:mah] is_a: GO:1902414 ! protein localization to cell junction intersection_of: GO:0008104 ! protein localization intersection_of: RO:0002339 GO:0045202 ! has target end location synapse relationship: RO:0002339 GO:0045202 ! has target end location synapse creation_date: 2010-03-29T10:58:53Z [Term] id: GO:0035433 name: acetate transmembrane transport namespace: biological_process def: "The process in which acetate is transported across a membrane. Acetate is the 2-carbon carboxylic acid ethanoic acid." [GOC:vw] synonym: "acetate membrane transport" EXACT [] is_a: GO:0006846 ! acetate transport is_a: GO:1905039 ! carboxylic acid transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002342 GO:0016020 ! results in transport across membrane intersection_of: RO:0004009 CHEBI:30089 ! has primary input acetate creation_date: 2010-04-08T10:59:01Z [Term] id: GO:0035435 name: phosphate ion transmembrane transport namespace: biological_process def: "The process in which a phosphate is transported across a membrane." [GOC:vw] synonym: "phosphate ion membrane transport" EXACT [] is_a: GO:0006817 ! phosphate ion transport is_a: GO:0098661 ! inorganic anion transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002342 GO:0016020 ! results in transport across membrane intersection_of: RO:0004009 CHEBI:35780 ! has primary input phosphate ion creation_date: 2010-04-08T11:24:06Z [Term] id: GO:0035441 name: cell migration involved in vasculogenesis namespace: biological_process def: "The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form de novo blood vessels and tubes." [GOC:dgh] is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: BFO:0000050 GO:0001570 ! part of vasculogenesis relationship: BFO:0000050 GO:0001570 ! part of vasculogenesis creation_date: 2010-04-09T03:53:01Z [Term] id: GO:0035556 name: intracellular signal transduction namespace: biological_process def: "The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell." [GOC:bf, GOC:jl, GOC:signaling, ISBN:3527303782] is_a: GO:0007165 ! signal transduction intersection_of: GO:0007165 ! signal transduction intersection_of: BFO:0000066 GO:0005622 ! occurs in intracellular anatomical structure relationship: BFO:0000066 GO:0005622 ! occurs in intracellular anatomical structure creation_date: 2010-05-14T01:14:37Z [Term] id: GO:0035592 name: establishment of protein localization to extracellular region namespace: biological_process def: "The directed movement of a protein to a specific location within the extracellular region." [GOC:bf, GOC:BHF] synonym: "establishment of protein localisation in extracellular region" EXACT [GOC:mah] synonym: "establishment of protein localization in extracellular region" EXACT [] is_a: GO:0045184 ! establishment of protein localization intersection_of: GO:0045184 ! establishment of protein localization intersection_of: RO:0002339 GO:0005576 ! has target end location extracellular region relationship: RO:0002339 GO:0005576 ! has target end location extracellular region creation_date: 2010-11-09T10:25:08Z [Term] id: GO:0035622 name: intrahepatic bile duct development namespace: biological_process def: "The progression of the intrahepatic bile ducts over time, from their formation to the mature structure. Intrahepatic bile ducts (bile ducts within the liver) collect bile from bile canaliculi in the liver, and connect to the extrahepatic bile ducts (bile ducts outside the liver)." [GOC:bf, PMID:20614624] synonym: "IHBD development" EXACT [PMID:20614624] synonym: "intrahepatic biliary duct development" EXACT [PMID:20614624] is_a: GO:0061009 ! common bile duct development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003704 ! results in development of intrahepatic bile duct relationship: BFO:0000050 GO:0001889 ! part of liver development relationship: RO:0002296 UBERON:0003704 ! results in development of intrahepatic bile duct creation_date: 2010-12-08T04:10:50Z [Term] id: GO:0035628 name: cystic duct development namespace: biological_process def: "The progression of the cystic duct over time, from its formation to the mature structure. The cystic duct runs from the gallbladder to the common bile duct." [PMID:20614624] is_a: GO:0061009 ! common bile duct development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001152 ! results in development of cystic duct relationship: RO:0002296 UBERON:0001152 ! results in development of cystic duct creation_date: 2010-12-10T01:24:28Z [Term] id: GO:0035645 name: enteric smooth muscle cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the intestine." [CL:0002504, GOC:BHF] synonym: "intestinal smooth muscle cell differentiation" EXACT [CL:0002504] is_a: GO:0051145 ! smooth muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0002504 ! results in acquisition of features of enteric smooth muscle cell relationship: BFO:0000050 GO:0048565 ! part of digestive tract development relationship: RO:0002315 CL:0002504 ! results in acquisition of features of enteric smooth muscle cell creation_date: 2011-01-21T02:58:58Z [Term] id: GO:0035701 name: hematopoietic stem cell migration namespace: biological_process def: "The orderly movement of a hematopoietic stem cell from one site to another. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system." [CL:0000037, GOC:BHF, PMID:20234092] synonym: "hemopoietic stem cell migration" EXACT [CL:0000037] is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000037 ! results in movement of hematopoietic stem cell relationship: RO:0002565 CL:0000037 ! results in movement of hematopoietic stem cell creation_date: 2011-02-28T03:20:36Z [Term] id: GO:0035725 name: sodium ion transmembrane transport namespace: biological_process def: "A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore." [GOC:vw] synonym: "sodium ion membrane transport" EXACT [] is_a: GO:0006814 ! sodium ion transport is_a: GO:0098655 ! monoatomic cation transmembrane transport is_a: GO:0098662 ! inorganic cation transmembrane transport intersection_of: GO:0055085 ! transmembrane transport intersection_of: RO:0004009 CHEBI:29101 ! has primary input sodium(1+) creation_date: 2011-03-10T02:52:36Z [Term] id: GO:0035735 name: intraciliary transport involved in cilium assembly namespace: biological_process def: "The bidirectional movement of large protein complexes along microtubules within a cilium that contributes to cilium assembly." [GOC:bf, GOC:cilia, Reactome:R-HSA-5620924.2] xref: Reactome:R-HSA-5620924.2 is_a: GO:0042073 ! intraciliary transport intersection_of: GO:0042073 ! intraciliary transport intersection_of: BFO:0000050 GO:0060271 ! part of cilium assembly relationship: BFO:0000050 GO:0060271 ! part of cilium assembly creation_date: 2011-03-17T10:55:42Z [Term] id: GO:0035736 name: cell proliferation involved in compound eye morphogenesis namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to compound eye morphogenesis." [GOC:bf, GOC:sart] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: BFO:0000050 GO:0001745 ! part of compound eye morphogenesis relationship: BFO:0000050 GO:0001745 ! part of compound eye morphogenesis creation_date: 2011-03-17T10:57:03Z [Term] id: GO:0035778 name: pronephric nephron tubule epithelial cell differentiation namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephric nephron tubule as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10, GOC:yaf, PMID:18787069] is_a: GO:0039014 ! cell differentiation involved in pronephros development is_a: GO:0072160 ! nephron tubule epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:1000090 ! results in acquisition of features of pronephric nephron tubule epithelial cell relationship: BFO:0000050 GO:0039020 ! part of pronephric nephron tubule development relationship: RO:0002315 CL:1000090 ! results in acquisition of features of pronephric nephron tubule epithelial cell creation_date: 2011-04-04T11:07:47Z [Term] id: GO:0035779 name: angioblast cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an angioblast cell. Angioblasts are one of the two products formed from hemangioblast cells (the other being pluripotent hemopoietic stem cells)." [CL:0000566, GOC:yaf] synonym: "angioblastic mesenchymal cell differentiation" EXACT [CL:0000566] is_a: GO:0048863 ! stem cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000566 ! results in acquisition of features of angioblastic mesenchymal cell relationship: BFO:0000050 GO:0001568 ! part of blood vessel development relationship: RO:0002315 CL:0000566 ! results in acquisition of features of angioblastic mesenchymal cell creation_date: 2011-04-04T11:10:38Z [Term] id: GO:0035787 name: cell migration involved in kidney development namespace: biological_process def: "The orderly movement of a cell from one site to another that will contribute to the progression of the kidney over time, from its formation to the mature organ." [GOC:bf, GOC:mtg_kidney_jan10, GOC:yaf] is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: BFO:0000050 GO:0001822 ! part of kidney development relationship: BFO:0000050 GO:0001822 ! part of kidney development creation_date: 2011-04-06T10:39:52Z [Term] id: GO:0035788 name: cell migration involved in metanephros development namespace: biological_process def: "The orderly movement of a cell from one site to another that will contribute to the progression of the metanephric kidney over time, from its formation to the mature organ." [GOC:bf, GOC:mtg_kidney_jan10, GOC:yaf] synonym: "cell migration involved in metanephric kidney development" EXACT [GOC:bf] is_a: GO:0035787 ! cell migration involved in kidney development intersection_of: GO:0016477 ! cell migration intersection_of: BFO:0000050 GO:0001656 ! part of metanephros development relationship: BFO:0000050 GO:0001656 ! part of metanephros development creation_date: 2011-04-06T10:42:21Z [Term] id: GO:0035799 name: ureter maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for the ureter to attain its fully functional state. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut." [GOC:bf, GOC:mtg_kidney_jan10, GOC:yaf, PMID:17881463] is_a: GO:0048799 ! animal organ maturation intersection_of: GO:0071695 ! anatomical structure maturation intersection_of: RO:0002299 UBERON:0000056 ! results in maturation of ureter relationship: BFO:0000050 GO:0072189 ! part of ureter development relationship: RO:0002299 UBERON:0000056 ! results in maturation of ureter creation_date: 2011-04-14T01:13:39Z [Term] id: GO:0035805 name: egg coat namespace: cellular_component def: "A specialized extracellular matrix that surrounds the plasma membrane of the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development." [PMID:16944418, PMID:17163408] is_a: GO:0031012 ! extracellular matrix intersection_of: GO:0031012 ! extracellular matrix intersection_of: BFO:0000050 CL:0000025 ! part of egg cell relationship: BFO:0000050 CL:0000025 ! part of egg cell relationship: RO:0002160 NCBITaxon:33208 ! only in taxon Metazoa relationship: RO:0002162 NCBITaxon:33208 {all_only="true"} ! in taxon Metazoa creation_date: 2011-04-19T02:07:23Z [Term] id: GO:0035809 name: regulation of urine volume namespace: biological_process def: "Any process that modulates the amount of urine excreted from the body over a unit of time." [GOC:mtg_25march11, GOC:yaf] synonym: "regulation of urinary volume" EXACT [] synonym: "regulation of urine flow" EXACT [] is_a: GO:0003014 ! renal system process is_a: GO:0050878 ! regulation of body fluid levels creation_date: 2011-04-20T01:17:38Z [Term] id: GO:0035834 name: indole alkaloid metabolic process namespace: biological_process def: "The chemical reactions and pathways involving an indole alkaloid, an alkaloid containing an indole skeleton." [GOC:yaf] synonym: "indole alkaloid metabolism" EXACT [GOC:bf] is_a: GO:0009820 ! alkaloid metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:38958 ! has primary input or output indole alkaloid relationship: RO:0004007 CHEBI:38958 ! has primary input or output indole alkaloid creation_date: 2011-05-04T03:17:44Z [Term] id: GO:0035835 name: indole alkaloid biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of an indole alkaloid, an alkaloid containing an indole skeleton." [GOC:yaf] synonym: "indole alkaloid anabolism" EXACT [GOC:bf] synonym: "indole alkaloid biosynthesis" EXACT [GOC:bf] synonym: "indole alkaloid formation" EXACT [GOC:bf] synonym: "indole alkaloid synthesis" EXACT [GOC:bf] is_a: GO:0009821 ! alkaloid biosynthetic process is_a: GO:0035834 ! indole alkaloid metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:38958 ! has primary output indole alkaloid relationship: RO:0004008 CHEBI:38958 ! has primary output indole alkaloid creation_date: 2011-05-04T03:18:31Z [Term] id: GO:0035844 name: cloaca development namespace: biological_process def: "The process whose specific outcome is the progression of the cloaca over time, from it's formation to the mature structure. The cloaca is the common chamber into which intestinal, genital and urinary canals open in vertebrates." [GOC:dgh, ISBN:0582227089] synonym: "cloacal development" EXACT [GOC:bf] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000162 ! results in development of cloaca relationship: BFO:0000050 GO:0001655 ! part of urogenital system development relationship: BFO:0000050 GO:0048546 ! part of digestive tract morphogenesis relationship: RO:0002296 UBERON:0000162 ! results in development of cloaca creation_date: 2011-05-06T01:54:35Z [Term] id: GO:0035846 name: oviduct epithelium development namespace: biological_process def: "The progression of the oviduct epithelium over time from its initial formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism. The oviduct epithelium is the specialized epithelium that lines the oviduct." [GOC:yaf, http://www.thefreedictionary.com/oviduct] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004804 ! results in development of oviduct epithelium relationship: BFO:0000050 GO:0060066 ! part of oviduct development relationship: RO:0002296 UBERON:0004804 ! results in development of oviduct epithelium creation_date: 2011-05-10T10:53:05Z [Term] id: GO:0035847 name: uterine epithelium development namespace: biological_process def: "The progression of an epithelium of the uterus over time from its initial formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure." [GOC:bf, GOC:yaf] synonym: "uterus epithelial development" EXACT [GOC:yaf] is_a: GO:0035846 ! oviduct epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0006955 ! results in development of uterine epithelium relationship: BFO:0000050 GO:0060065 ! part of uterus development relationship: RO:0002296 UBERON:0006955 ! results in development of uterine epithelium creation_date: 2011-05-10T10:57:45Z [Term] id: GO:0035848 name: oviduct morphogenesis namespace: biological_process def: "The process in which anatomical structures of the oviduct are generated and organized. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism." [GOC:yaf, http://www.thefreedictionary.com/oviduct] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0009887 ! animal organ morphogenesis is_a: GO:0035239 ! tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000993 ! results in morphogenesis of oviduct relationship: BFO:0000050 GO:0060066 ! part of oviduct development relationship: RO:0002298 UBERON:0000993 ! results in morphogenesis of oviduct creation_date: 2011-05-10T11:01:20Z [Term] id: GO:0035850 name: epithelial cell differentiation involved in kidney development namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an epithelial cell that characterize the cells of the kidney as it progresses from its formation to the mature state." [GOC:bf, GOC:mtg_kidney_jan10, GOC:yaf, PMID:16216236] is_a: GO:0030855 ! epithelial cell differentiation is_a: GO:0061005 ! cell differentiation involved in kidney development intersection_of: GO:0030855 ! epithelial cell differentiation intersection_of: BFO:0000050 GO:0001822 ! part of kidney development creation_date: 2011-05-11T11:34:21Z [Term] id: GO:0035855 name: megakaryocyte development namespace: biological_process def: "The process whose specific outcome is the progression of a megakaryocyte cell over time, from its formation to the mature structure. Megakaryocyte development does not include the steps involved in committing a cell to a megakaryocyte fate. A megakaryocyte is a giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow." [CL:0000556, GOC:BHF, GOC:vk] synonym: "megakaryocyte cell development" EXACT [GOC:bf] is_a: GO:0061515 ! myeloid cell development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 CL:0000556 ! results in development of megakaryocyte relationship: BFO:0000050 GO:0030219 ! part of megakaryocyte differentiation relationship: RO:0002296 CL:0000556 ! results in development of megakaryocyte creation_date: 2011-05-13T01:28:06Z [Term] id: GO:0035869 name: ciliary transition zone namespace: cellular_component def: "A region of the cilium between the basal body and proximal segment that is characterized by Y-shaped assemblages that connect axonemal microtubules to the ciliary membrane. The ciliary transition zone appears to function as a gate that controls ciliary membrane composition and separates the cytosol from the ciliary plasm." [GOC:cilia, GOC:kmv, PMID:21422230] synonym: "cilial transition zone" EXACT [] synonym: "cilium transition zone" EXACT [] is_a: GO:0110165 ! cellular anatomical entity relationship: BFO:0000050 GO:0005929 ! part of cilium creation_date: 2011-05-25T03:09:58Z [Term] id: GO:0035883 name: enteroendocrine cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an enteroendocrine cell. Enteroendocrine cells are hormonally active epithelial cells in the gut that constitute the diffuse neuroendocrine system." [CL:0000164, GOC:bf] is_a: GO:0002067 ! glandular epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000164 ! results in acquisition of features of enteroendocrine cell relationship: RO:0002315 CL:0000164 ! results in acquisition of features of enteroendocrine cell creation_date: 2011-06-06T11:48:51Z [Term] id: GO:0035886 name: vascular associated smooth muscle cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a vascular smooth muscle cell." [GOC:sl, PMID:16151017, PMID:18267954] synonym: "vascular smooth muscle cell differentiation" EXACT [] synonym: "VSMC differentiation" EXACT [PMID:16151017] is_a: GO:0051145 ! smooth muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000359 ! results in acquisition of features of vascular associated smooth muscle cell relationship: BFO:0000050 GO:0001944 ! part of vasculature development relationship: RO:0002315 CL:0000359 ! results in acquisition of features of vascular associated smooth muscle cell creation_date: 2011-06-08T11:23:52Z [Term] id: GO:0035887 name: aortic smooth muscle cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell surrounding the aorta." [GOC:sl] is_a: GO:0035886 ! vascular associated smooth muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0002539 ! results in acquisition of features of aortic smooth muscle cell relationship: RO:0002315 CL:0002539 ! results in acquisition of features of aortic smooth muscle cell creation_date: 2011-06-08T11:34:26Z [Term] id: GO:0035904 name: aorta development namespace: biological_process def: "The progression of the aorta over time, from its initial formation to the mature structure. An aorta is an artery that carries blood from the heart to other parts of the body." [GOC:bf, GOC:dgh, MA:0000062, UBERON:0000947, Wikipedia:Aorta] is_a: GO:0060840 ! artery development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000947 ! results in development of aorta relationship: RO:0002296 UBERON:0000947 ! results in development of aorta creation_date: 2011-06-24T11:00:07Z [Term] id: GO:0035905 name: ascending aorta development namespace: biological_process def: "The progression of the ascending aorta over time, from its initial formation to the mature structure. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once." [GOC:bf, GOC:dgh, MA:0002570, UBERON:0001496, Wikipedia:Ascending_aorta] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001496 ! results in development of ascending aorta relationship: BFO:0000050 GO:0035904 ! part of aorta development relationship: RO:0002296 UBERON:0001496 ! results in development of ascending aorta creation_date: 2011-06-24T11:02:01Z [Term] id: GO:0035906 name: descending aorta development namespace: biological_process def: "The progression of the descending aorta over time, from its initial formation to the mature structure. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once." [GOC:bf, GOC:dgh, MA:0002571, UBERON:0001514, Wikipedia:Descending_aorta] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001514 ! results in development of descending aorta relationship: BFO:0000050 GO:0035904 ! part of aorta development relationship: RO:0002296 UBERON:0001514 ! results in development of descending aorta creation_date: 2011-06-24T11:05:22Z [Term] id: GO:0035907 name: dorsal aorta development namespace: biological_process def: "The progression of the dorsal aorta over time, from its initial formation to the mature structure. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once." [GOC:bf, GOC:dgh, UBERON:0005805, Wikipedia:Aorta, ZFA:0000014] is_a: GO:0035904 ! aorta development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005805 ! results in development of dorsal aorta relationship: RO:0002296 UBERON:0005805 ! results in development of dorsal aorta creation_date: 2011-06-24T11:07:01Z [Term] id: GO:0035909 name: aorta morphogenesis namespace: biological_process def: "The process in which the anatomical structures of an aorta are generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body." [GOC:bf, GOC:dgh, MA:0000062, UBERON:0000947, Wikipedia:Aorta] is_a: GO:0048844 ! artery morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000947 ! results in morphogenesis of aorta relationship: BFO:0000050 GO:0035904 ! part of aorta development relationship: RO:0002298 UBERON:0000947 ! results in morphogenesis of aorta creation_date: 2011-06-24T11:11:11Z [Term] id: GO:0035910 name: ascending aorta morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the ascending aorta are generated and organized. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once." [GOC:bf, GOC:dgh, MA:0002570, UBERON:0001496, Wikipedia:Ascending_aorta] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001496 ! results in morphogenesis of ascending aorta relationship: BFO:0000050 GO:0035905 ! part of ascending aorta development relationship: BFO:0000050 GO:0035909 ! part of aorta morphogenesis relationship: RO:0002298 UBERON:0001496 ! results in morphogenesis of ascending aorta creation_date: 2011-06-24T11:14:52Z [Term] id: GO:0035911 name: descending aorta morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the descending aorta are generated and organized. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once." [GOC:bf, GOC:dgh, MA:0002571, UBERON:0001514, Wikipedia:Descending_aorta] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001514 ! results in morphogenesis of descending aorta relationship: BFO:0000050 GO:0035906 ! part of descending aorta development relationship: BFO:0000050 GO:0035909 ! part of aorta morphogenesis relationship: RO:0002298 UBERON:0001514 ! results in morphogenesis of descending aorta creation_date: 2011-06-24T11:19:24Z [Term] id: GO:0035912 name: dorsal aorta morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the dorsal aorta are generated and organized. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once." [GOC:bf, GOC:dgh, UBERON:0005805, Wikipedia:Aorta, ZFA:0000014] is_a: GO:0035909 ! aorta morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0005805 ! results in morphogenesis of dorsal aorta relationship: BFO:0000050 GO:0035907 ! part of dorsal aorta development relationship: RO:0002298 UBERON:0005805 ! results in morphogenesis of dorsal aorta creation_date: 2011-06-24T11:22:14Z [Term] id: GO:0035914 name: skeletal muscle cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle cell, a somatic cell located in skeletal muscle." [CL:0000188, GOC:BHF, GOC:vk] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000188 ! results in acquisition of features of cell of skeletal muscle relationship: BFO:0000050 GO:0007519 ! part of skeletal muscle tissue development relationship: RO:0002315 CL:0000188 ! results in acquisition of features of cell of skeletal muscle creation_date: 2011-06-24T02:36:19Z [Term] id: GO:0035929 name: steroid hormone secretion namespace: biological_process def: "The regulated release of any steroid that acts as a hormone into the circulatory system." [GOC:sl] is_a: GO:0060986 ! endocrine hormone secretion is_a: GO:0140353 ! lipid export from cell intersection_of: GO:0046903 ! secretion intersection_of: RO:0004009 CHEBI:26764 ! has primary input steroid hormone relationship: RO:0004009 CHEBI:26764 ! has primary input steroid hormone creation_date: 2011-07-20T01:01:00Z [Term] id: GO:0035935 name: androgen secretion namespace: biological_process def: "The regulated release of an androgen into the circulatory system. Androgens are steroid hormones that stimulate or control the development and maintenance of masculine characteristics in vertebrates." [GOC:sl] is_a: GO:0035929 ! steroid hormone secretion creation_date: 2011-07-20T01:11:31Z [Term] id: GO:0035987 name: endodermal cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized features of an endoderm cell, a cell of the inner of the three germ layers of the embryo." [CL:0000223, GOC:yaf, PMID:17624332] synonym: "endoderm cell differentiation" EXACT [CL:0000223] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000223 ! results in acquisition of features of endodermal cell relationship: BFO:0000050 GO:0001706 ! part of endoderm formation relationship: RO:0002315 CL:0000223 ! results in acquisition of features of endodermal cell creation_date: 2011-08-25T04:50:36Z [Term] id: GO:0035989 name: tendon development namespace: biological_process def: "The process whose specific outcome is the progression of a tendon over time, from its formation to the mature structure. A tendon is a fibrous, strong, connective tissue that connects muscle to bone or integument and is capable of withstanding tension. Tendons and muscles work together to exert a pulling force." [GOC:yaf, PMID:21412429, UBERON:0000043] is_a: GO:0061448 ! connective tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000043 ! results in development of tendon relationship: RO:0002296 UBERON:0000043 ! results in development of tendon creation_date: 2011-08-26T04:14:30Z [Term] id: GO:0035992 name: tendon formation namespace: biological_process def: "The process that gives rise to a tendon. This process pertains to the initial formation of a tendon from unspecified parts." [GOC:yaf, PMID:17567668, UBERON:0000043] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0000043 ! results in formation of anatomical entity tendon relationship: BFO:0000050 GO:0035989 ! part of tendon development relationship: RO:0002297 UBERON:0000043 ! results in formation of anatomical entity tendon creation_date: 2011-08-30T01:35:10Z [Term] id: GO:0036072 name: direct ossification namespace: biological_process def: "The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance, that does not require the replacement of preexisting tissues." [GO_REF:0000034] is_a: GO:0001503 ! ossification creation_date: 2011-12-19T01:47:22Z [Term] id: GO:0036093 name: germ cell proliferation namespace: biological_process def: "The multiplication or reproduction of germ cells, reproductive cells in multicellular organisms, resulting in the expansion of a cell population." [CL:0000586, GOC:kmv] is_a: GO:0008283 ! cell population proliferation is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000586 ! acts on population of germ cell relationship: BFO:0000050 GO:0007276 ! part of gamete generation relationship: RO:0012003 CL:0000586 ! acts on population of germ cell creation_date: 2012-01-17T04:06:27Z [Term] id: GO:0036099 name: female germ-line stem cell population maintenance namespace: biological_process def: "The process by which an organism or tissue maintains a population of female germ-line stem cells." [GOC:sart] is_a: GO:0030718 ! germ-line stem cell population maintenance intersection_of: GO:0098727 ! maintenance of cell number intersection_of: RO:0012003 CL:0000022 ! acts on population of female germ line stem cell relationship: RO:0012003 CL:0000022 ! acts on population of female germ line stem cell creation_date: 2012-01-26T01:58:10Z [Term] id: GO:0036145 name: dendritic cell homeostasis namespace: biological_process def: "The process of regulating the proliferation and elimination of dendritic cells such that the total number of dendritic cells within a whole or part of an organism is stable over time in the absence of an outside stimulus." [CL:0000451, GOC:uh, PMID:12570827, PMID:19176316] is_a: GO:0001776 ! leukocyte homeostasis intersection_of: GO:0048872 ! homeostasis of number of cells intersection_of: RO:0012003 CL:0000451 ! acts on population of dendritic cell relationship: RO:0012003 CL:0000451 ! acts on population of dendritic cell creation_date: 2012-03-12T11:05:36Z [Term] id: GO:0036194 name: muscle cell projection namespace: cellular_component def: "A prolongation or process extending from a muscle cell. A muscle cell is a mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns." [CL:0000187, GOC:kmv, PMID:15930100, PMID:22464329] synonym: "myocyte projection" EXACT [CL:0000187] is_a: GO:0120025 ! plasma membrane bounded cell projection is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: GO:0120025 ! plasma membrane bounded cell projection intersection_of: BFO:0000050 CL:0000187 ! part of muscle cell relationship: BFO:0000050 CL:0000187 ! part of muscle cell creation_date: 2012-04-20T10:20:47Z [Term] id: GO:0036195 name: muscle cell projection membrane namespace: cellular_component def: "The portion of the plasma membrane surrounding a muscle cell projection." [CL:0000187, GOC:kmv, PMID:15930100, PMID:22464329] is_a: GO:0031253 ! cell projection membrane is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: GO:0031253 ! cell projection membrane intersection_of: BFO:0000050 GO:0036194 ! part of muscle cell projection relationship: BFO:0000050 GO:0036194 ! part of muscle cell projection creation_date: 2012-04-20T10:21:51Z [Term] id: GO:0036293 name: response to decreased oxygen levels namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen." [GOC:al] synonym: "response to lowered oxygen levels" EXACT [GOC:bf] is_a: GO:0070482 ! response to oxygen levels creation_date: 2012-07-20T01:05:46Z [Term] id: GO:0036304 name: umbilical cord morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the umbilical cord are generated and organized. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta." [GOC:BHF, GOC:gr, PMID:15107403] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002331 ! results in morphogenesis of umbilical cord relationship: BFO:0000050 GO:0061027 ! part of umbilical cord development relationship: RO:0002298 UBERON:0002331 ! results in morphogenesis of umbilical cord creation_date: 2012-08-08T10:12:11Z [Term] id: GO:0036333 name: hepatocyte homeostasis namespace: biological_process def: "Any biological process involved in the maintenance of the steady-state number of hepatocytes within a population of cells. Hepatocytes are specialized epithelial cells of the liver that are organized into interconnected plates called lobules." [CL:0000182, GOC:nhn, PMID:19878874] is_a: GO:0048872 ! homeostasis of number of cells intersection_of: GO:0048872 ! homeostasis of number of cells intersection_of: RO:0012003 CL:0000182 ! acts on population of hepatocyte relationship: RO:0012003 CL:0000182 ! acts on population of hepatocyte creation_date: 2012-09-05T10:17:07Z [Term] id: GO:0036334 name: epidermal stem cell homeostasis namespace: biological_process def: "Any biological process involved in the maintenance of the steady-state number of epidermal stem cells within a population of cells." [CL:1000428, GOC:nhn, PMID:17666529] is_a: GO:0048872 ! homeostasis of number of cells intersection_of: GO:0048872 ! homeostasis of number of cells intersection_of: RO:0012003 CL:1000428 ! acts on population of stem cell of epidermis relationship: RO:0012003 CL:1000428 ! acts on population of stem cell of epidermis creation_date: 2012-09-05T10:21:23Z [Term] id: GO:0036336 name: dendritic cell migration namespace: biological_process def: "The movement of a dendritic cell within or between different tissues and organs of the body." [CL:0000451, GOC:nhn, PMID:19339990] is_a: GO:0071674 ! mononuclear cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000451 ! results in movement of dendritic cell relationship: RO:0002565 CL:0000451 ! results in movement of dendritic cell creation_date: 2012-09-05T10:24:46Z [Term] id: GO:0036342 name: post-anal tail morphogenesis namespace: biological_process def: "The process in which a post-anal tail is generated and organized. A post-anal tail is a muscular region of the body that extends posterior to the anus. The post-anal tail may aid locomotion and balance." [GOC:bf, GOC:kmv, Wikipedia:Chordate] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0007812 ! results in morphogenesis of post-anal tail relationship: RO:0002160 NCBITaxon:7711 ! only in taxon Chordata relationship: RO:0002162 NCBITaxon:7711 {all_only="true"} ! in taxon Chordata relationship: RO:0002298 UBERON:0007812 ! results in morphogenesis of post-anal tail creation_date: 2012-09-11T13:54:49Z [Term] id: GO:0036477 name: somatodendritic compartment namespace: cellular_component def: "The region of a neuron that includes the cell body (cell soma) and dendrite(s), but excludes the axon." [GOC:pad, GOC:PARL] is_a: GO:0110165 ! cellular anatomical entity relationship: BFO:0000050 CL:0000540 ! part of neuron creation_date: 2014-07-24T10:06:19Z [Term] id: GO:0036484 name: trunk neural crest cell migration namespace: biological_process def: "The characteristic movement of trunk neural crest cells from the neural tube to other locations in the vertebrate embryo." [GOC:bf, GOC:mat, GOC:PARL, PMID:2387238] synonym: "trunk NCC migration" EXACT [PMID:2387238] is_a: GO:0001755 ! neural crest cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000011 ! results in movement of migratory trunk neural crest cell relationship: BFO:0000050 GO:0035290 ! part of trunk segmentation relationship: RO:0002565 CL:0000011 ! results in movement of migratory trunk neural crest cell creation_date: 2014-08-26T15:27:44Z [Term] id: GO:0036504 name: Golgi membrane fusion namespace: biological_process def: "The joining of two lipid bilayers that surround the Golgi apparatus to form a single Golgi membrane." [GOC:bf, GOC:PARL, PMID:12473691] synonym: "Golgi apparatus membrane fusion" EXACT [] synonym: "membrane fusion involved in Golgi reassembly" EXACT [GOC:bf] synonym: "post-mitotic fusion of Golgi membranes" EXACT [PMID:10811609] is_a: GO:0090174 ! organelle membrane fusion intersection_of: GO:0061025 ! membrane fusion intersection_of: RO:0012008 GO:0000139 ! results in fusion of Golgi membrane relationship: BFO:0000050 GO:0090168 ! part of Golgi reassembly relationship: RO:0012008 GO:0000139 ! results in fusion of Golgi membrane creation_date: 2015-05-21T10:05:06Z [Term] id: GO:0039006 name: pronephric nephron tubule formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a pronephric nephron tubule from unspecified parts. A pronephric nephron tubule is an epithelial tube that is part of a nephron in the pronephros." [GOC:mtg_kidney_jan10] synonym: "pronephric tubule formation" EXACT [GOC:mtg_kidney_jan10] synonym: "pronephros tubule formation" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0072079 ! nephron tubule formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0005310 ! results in formation of anatomical entity pronephric nephron tubule relationship: BFO:0000050 GO:0039008 ! part of pronephric nephron tubule morphogenesis relationship: BFO:0000050 GO:0072116 ! part of pronephros formation relationship: RO:0002297 UBERON:0005310 ! results in formation of anatomical entity pronephric nephron tubule creation_date: 2010-07-02T09:37:27Z [Term] id: GO:0039007 name: pronephric nephron morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the pronephric nephron are generated and organized. A pronephric nephron is the functional unit of the pronephros." [GOC:mtg_kidney_jan10] is_a: GO:0072028 ! nephron morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0005309 ! results in morphogenesis of pronephric nephron relationship: BFO:0000050 GO:0039019 ! part of pronephric nephron development relationship: BFO:0000050 GO:0072114 ! part of pronephros morphogenesis relationship: RO:0002298 UBERON:0005309 ! results in morphogenesis of pronephric nephron creation_date: 2010-07-02T09:38:53Z [Term] id: GO:0039008 name: pronephric nephron tubule morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a pronephric nephron tubule are generated and organized from an epithelium. A pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron." [GOC:mtg_kidney_jan10, ZFA:00001558] is_a: GO:0072078 ! nephron tubule morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0005310 ! results in morphogenesis of pronephric nephron tubule relationship: BFO:0000050 GO:0039007 ! part of pronephric nephron morphogenesis relationship: BFO:0000050 GO:0039020 ! part of pronephric nephron tubule development relationship: RO:0002298 UBERON:0005310 ! results in morphogenesis of pronephric nephron tubule creation_date: 2010-07-02T09:45:55Z [Term] id: GO:0039014 name: cell differentiation involved in pronephros development namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephros as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] synonym: "cell differentiation involved in pronephric kidney development" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0061005 ! cell differentiation involved in kidney development intersection_of: GO:0030154 ! cell differentiation intersection_of: BFO:0000050 GO:0048793 ! part of pronephros development relationship: BFO:0000050 GO:0048793 ! part of pronephros development creation_date: 2010-07-02T09:59:25Z [Term] id: GO:0039015 name: cell proliferation involved in pronephros development namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of the population in the pronephros." [GOC:mtg_kidney_jan10] synonym: "cell proliferation involved in pronephric kidney development" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0072111 ! cell proliferation involved in kidney development intersection_of: GO:0008283 ! cell population proliferation intersection_of: BFO:0000050 GO:0048793 ! part of pronephros development relationship: BFO:0000050 GO:0048793 ! part of pronephros development creation_date: 2010-07-02T10:01:49Z [Term] id: GO:0039016 name: cell-cell signaling involved in pronephros development namespace: biological_process def: "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the pronephros over time, from its formation to the mature organ." [GOC:mtg_kidney_jan10] synonym: "cell-cell signaling involved in pronephric kidney development" EXACT [GOC:mtg_kidney_jan10] synonym: "cell-cell signalling involved in pronephros development" EXACT [GOC:mah] is_a: GO:0060995 ! cell-cell signaling involved in kidney development intersection_of: GO:0007267 ! cell-cell signaling intersection_of: BFO:0000050 GO:0048793 ! part of pronephros development relationship: BFO:0000050 GO:0048793 ! part of pronephros development creation_date: 2010-07-02T10:03:16Z [Term] id: GO:0039017 name: pattern specification involved in pronephros development namespace: biological_process def: "Any developmental process that results in the creation of defined areas or spaces within the pronephros to which cells respond and eventually are instructed to differentiate." [GOC:mtg_kidney_jan10] synonym: "pattern specification involved in pronephric kidney development" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0061004 ! pattern specification involved in kidney development intersection_of: GO:0007389 ! pattern specification process intersection_of: BFO:0000050 GO:0048793 ! part of pronephros development relationship: BFO:0000050 GO:0048793 ! part of pronephros development creation_date: 2010-07-02T10:04:39Z [Term] id: GO:0039019 name: pronephric nephron development namespace: biological_process def: "The process whose specific outcome is the progression of the pronephric nephron over time, from its formation to the mature structure. A pronephric nephron is the functional unit of the pronephros." [GOC:mtg_kidney_jan10, XAO:00002785] is_a: GO:0072006 ! nephron development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005309 ! results in development of pronephric nephron relationship: BFO:0000050 GO:0048793 ! part of pronephros development relationship: RO:0002296 UBERON:0005309 ! results in development of pronephric nephron creation_date: 2010-07-02T10:10:20Z [Term] id: GO:0039020 name: pronephric nephron tubule development namespace: biological_process def: "The process whose specific outcome is the progression of a pronephric nephron tubule over time, from its formation to the mature structure. The pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron and connects the filtration unit (glomerulus or glomus) of the pronephros to the pronephric duct." [GOC:mtg_kidney_jan10, PMID:19909807, PMID:9268568] is_a: GO:0072080 ! nephron tubule development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005310 ! results in development of pronephric nephron tubule relationship: BFO:0000050 GO:0039019 ! part of pronephric nephron development relationship: RO:0002296 UBERON:0005310 ! results in development of pronephric nephron tubule creation_date: 2010-07-02T10:11:36Z [Term] id: GO:0039022 name: pronephric duct development namespace: biological_process def: "The process whose specific outcome is the progression of the pronephric duct over time, from its formation to the mature structure. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the pronephric kidney." [GOC:mtg_kidney_jan10, PMID:15647339, XAO:0000063, ZFA:0000150] is_a: GO:0072176 ! nephric duct development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003060 ! results in development of pronephric duct relationship: BFO:0000050 GO:0048793 ! part of pronephros development relationship: RO:0002296 UBERON:0003060 ! results in development of pronephric duct creation_date: 2010-07-02T10:15:03Z [Term] id: GO:0039023 name: pronephric duct morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the pronephric duct are generated and organized. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the kidney." [GOC:mtg_kidney_jan10, XAO:0000063, ZFA:0000150] is_a: GO:0072178 ! nephric duct morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003060 ! results in morphogenesis of pronephric duct relationship: BFO:0000050 GO:0039022 ! part of pronephric duct development relationship: BFO:0000050 GO:0072114 ! part of pronephros morphogenesis relationship: RO:0002298 UBERON:0003060 ! results in morphogenesis of pronephric duct creation_date: 2010-07-02T10:18:09Z [Term] id: GO:0040003 name: chitin-based cuticle development namespace: biological_process def: "Synthesis and deposition of a chitin-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this process is found in Drosophila melanogaster." [GOC:mtg_sensu] synonym: "chitin-based cuticle anabolism" EXACT [] synonym: "chitin-based cuticle biosynthetic process" EXACT [] synonym: "chitin-based cuticle formation" EXACT [] synonym: "chitin-based cuticle synthesis" EXACT [] is_a: GO:0042335 ! cuticle development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001001 ! results in development of chitin-based cuticle relationship: RO:0002160 NCBITaxon:6656 ! only in taxon Arthropoda relationship: RO:0002162 NCBITaxon:6656 {all_only="true"} ! in taxon Arthropoda relationship: RO:0002296 UBERON:0001001 ! results in development of chitin-based cuticle [Term] id: GO:0040007 name: growth namespace: biological_process def: "The increase in size or mass of an entire organism, a part of an organism or a cell." [GOC:bf, GOC:ma] is_a: GO:0008150 ! biological_process relationship: RO:0002160 NCBITaxon:131567 ! only in taxon cellular organisms relationship: RO:0002162 NCBITaxon:131567 {all_only="true"} ! in taxon cellular organisms [Term] id: GO:0040008 name: regulation of growth namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development." [GOC:ems, GOC:mah] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0040007 ! regulates (processual) growth relationship: RO:0002211 GO:0040007 ! regulates (processual) growth [Term] id: GO:0040011 name: locomotion namespace: biological_process def: "Self-propelled movement of a cell or organism from one location to another." [GOC:dgh] is_a: GO:0008150 ! biological_process [Term] id: GO:0040012 name: regulation of locomotion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of locomotion of a cell or organism." [GOC:ems] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0040011 ! regulates (processual) locomotion relationship: RO:0002211 GO:0040011 ! regulates (processual) locomotion [Term] id: GO:0040013 name: negative regulation of locomotion namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of locomotion of a cell or organism." [GOC:go_curators] synonym: "down regulation of locomotion" EXACT [] synonym: "down-regulation of locomotion" EXACT [] synonym: "downregulation of locomotion" EXACT [] is_a: GO:0040012 ! regulation of locomotion is_a: GO:0048519 ! negative regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0040011 ! negatively regulates locomotion relationship: RO:0002212 GO:0040011 ! negatively regulates locomotion [Term] id: GO:0040014 name: regulation of multicellular organism growth namespace: biological_process def: "Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size." [GOC:dph, GOC:ems, GOC:tb] synonym: "regulation of body growth" EXACT [GOC:dph, GOC:tb] synonym: "regulation of body size" EXACT [GOC:dph, GOC:tb] is_a: GO:0048638 ! regulation of developmental growth is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0035264 ! regulates (processual) multicellular organism growth relationship: RO:0002211 GO:0035264 ! regulates (processual) multicellular organism growth [Term] id: GO:0040015 name: negative regulation of multicellular organism growth namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organism to reach its usual body size." [GOC:dph, GOC:ems, GOC:tb] synonym: "negative regulation of body growth" EXACT [GOC:dph, GOC:tb] synonym: "negative regulation of body size" EXACT [GOC:dph, GOC:tb] is_a: GO:0040014 ! regulation of multicellular organism growth is_a: GO:0048640 ! negative regulation of developmental growth is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0035264 ! negatively regulates multicellular organism growth relationship: RO:0002212 GO:0035264 ! negatively regulates multicellular organism growth [Term] id: GO:0040016 name: embryonic cleavage namespace: biological_process def: "The first few specialized divisions of an activated animal egg." [GOC:clt, ISBN:0070524300] is_a: GO:0051301 ! cell division relationship: BFO:0000050 GO:0009790 ! part of embryo development [Term] id: GO:0040017 name: positive regulation of locomotion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism." [GOC:go_curators] synonym: "up regulation of locomotion" EXACT [] synonym: "up-regulation of locomotion" EXACT [] synonym: "upregulation of locomotion" EXACT [] is_a: GO:0040012 ! regulation of locomotion is_a: GO:0048518 ! positive regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0040011 ! positively regulates locomotion relationship: RO:0002213 GO:0040011 ! positively regulates locomotion [Term] id: GO:0040018 name: positive regulation of multicellular organism growth namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "positive regulation of body growth" EXACT [GOC:dph, GOC:tb] synonym: "positive regulation of body size" EXACT [GOC:dph, GOC:tb] is_a: GO:0040014 ! regulation of multicellular organism growth is_a: GO:0048639 ! positive regulation of developmental growth is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0035264 ! positively regulates multicellular organism growth relationship: RO:0002213 GO:0035264 ! positively regulates multicellular organism growth [Term] id: GO:0040019 name: positive regulation of embryonic development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of embryonic development." [GOC:go_curators] synonym: "up regulation of embryonic development" EXACT [] synonym: "up-regulation of embryonic development" EXACT [] synonym: "upregulation of embryonic development" EXACT [] is_a: GO:0045995 ! regulation of embryonic development is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0009790 ! positively regulates embryo development relationship: RO:0002213 GO:0009790 ! positively regulates embryo development [Term] id: GO:0040020 name: regulation of meiotic nuclear division namespace: biological_process def: "Any process that modulates the frequency, rate or extent of meiotic nuclear division, the process in which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes." [GOC:ems, GOC:ma] is_a: GO:0010564 ! regulation of cell cycle process is_a: GO:0051445 ! regulation of meiotic cell cycle is_a: GO:0051783 ! regulation of nuclear division intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0140013 ! regulates (processual) meiotic nuclear division relationship: RO:0002211 GO:0140013 ! regulates (processual) meiotic nuclear division [Term] id: GO:0040034 name: regulation of development, heterochronic namespace: biological_process def: "Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and the rate at which this time point is reached." [PMID:9442909] synonym: "heterochronic regulation of development" EXACT [] synonym: "temporal regulation of development" EXACT [] is_a: GO:0050793 ! regulation of developmental process [Term] id: GO:0042063 name: gliogenesis namespace: biological_process def: "The process that results in the generation of glial cells. This includes the production of glial progenitors and their differentiation into mature glia." [GOC:dgh, GOC:jid] is_a: GO:0022008 ! neurogenesis intersection_of: GO:0008150 ! biological_process intersection_of: RO:0002297 CL:0000125 ! results in formation of anatomical entity glial cell relationship: RO:0002297 CL:0000125 ! results in formation of anatomical entity glial cell [Term] id: GO:0042065 name: glial cell growth namespace: biological_process def: "Growth of glial cells, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system." [GOC:dph, GOC:isa_complete, GOC:jid] is_a: GO:0048588 ! developmental cell growth intersection_of: GO:0040007 ! growth intersection_of: RO:0002343 CL:0000125 ! results in growth of glial cell relationship: BFO:0000050 GO:0042063 ! part of gliogenesis relationship: RO:0002343 CL:0000125 ! results in growth of glial cell [Term] id: GO:0042069 name: regulation of catecholamine metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catecholamines." [GOC:go_curators] synonym: "regulation of catecholamine metabolism" EXACT [] is_a: GO:0031323 ! regulation of cellular metabolic process is_a: GO:0033238 ! regulation of amine metabolic process is_a: GO:0080090 ! regulation of primary metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006584 ! regulates (processual) catecholamine metabolic process relationship: RO:0002211 GO:0006584 ! regulates (processual) catecholamine metabolic process [Term] id: GO:0042073 name: intraciliary transport namespace: biological_process def: "The bidirectional movement of large protein complexes along microtubules within a cilium, mediated by motor proteins." [GOC:cilia, GOC:kmv, PMID:17981739, PMID:18180368, PMID:22869374, Reactome:R-HSA-5620924.2] synonym: "intraflagellar transport" EXACT [] synonym: "intraflagellar transport involved in cilium organization" EXACT [] synonym: "intraflagellar transport involved in microtubule-based flagellum organisation" EXACT [] xref: Wikipedia:Intraflagellar_transport is_a: GO:0010970 ! transport along microtubule is_a: GO:0031503 ! protein-containing complex localization intersection_of: GO:0006810 ! transport intersection_of: BFO:0000066 GO:0005929 ! occurs in cilium intersection_of: RO:0002341 GO:0005874 ! results in transport along microtubule intersection_of: RO:0004009 GO:0032991 ! has primary input protein-containing complex relationship: BFO:0000050 GO:0044782 ! part of cilium organization relationship: BFO:0000066 GO:0005929 ! occurs in cilium relationship: RO:0002160 NCBITaxon:2759 ! only in taxon Eukaryota relationship: RO:0002162 NCBITaxon:2759 {all_only="true"} ! in taxon Eukaryota [Term] id: GO:0042074 name: cell migration involved in gastrulation namespace: biological_process def: "The migration of individual cells within the blastocyst to help establish the multi-layered body plan of the organism (gastrulation). For example, the migration of cells from the surface to the interior of the embryo (ingression)." [GOC:jl, http://www.cellmigration.org/, ISBN:0878932437] is_a: GO:0001667 ! ameboidal-type cell migration intersection_of: GO:0016477 ! cell migration intersection_of: BFO:0000050 GO:0007369 ! part of gastrulation relationship: BFO:0000050 GO:0007369 ! part of gastrulation [Term] id: GO:0042078 name: germ-line stem cell division namespace: biological_process def: "The self-renewing division of a germline stem cell to produce a daughter stem cell and a daughter germ cell, which will divide to form the gametes." [GOC:jid, PMID:2279698] synonym: "germ-line stem cell renewal" EXACT [] is_a: GO:0017145 ! stem cell division is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism intersection_of: GO:0051301 ! cell division intersection_of: RO:0004009 CL:0000014 ! has primary input germ line stem cell relationship: BFO:0000050 GO:0007281 ! part of germ cell development relationship: RO:0004009 CL:0000014 ! has primary input germ line stem cell [Term] id: GO:0042098 name: T cell proliferation namespace: biological_process def: "The expansion of a T cell population by cell division. Follows T cell activation." [GOC:jl] synonym: "T lymphocyte proliferation" EXACT [] synonym: "T-cell proliferation" EXACT [] synonym: "T-lymphocyte proliferation" EXACT [] is_a: GO:0042110 ! T cell activation is_a: GO:0046651 ! lymphocyte proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000084 ! acts on population of T cell relationship: RO:0012003 CL:0000084 ! acts on population of T cell [Term] id: GO:0042102 name: positive regulation of T cell proliferation namespace: biological_process def: "Any process that activates or increases the rate or extent of T cell proliferation." [GOC:ai] synonym: "positive regulation of T lymphocyte proliferation" EXACT [] synonym: "positive regulation of T-lymphocyte proliferation" EXACT [] synonym: "up regulation of T cell proliferation" EXACT [] synonym: "up-regulation of T cell proliferation" EXACT [] synonym: "upregulation of T cell proliferation" EXACT [] is_a: GO:0042129 ! regulation of T cell proliferation is_a: GO:0050671 ! positive regulation of lymphocyte proliferation is_a: GO:0050870 ! positive regulation of T cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0042098 ! positively regulates T cell proliferation relationship: RO:0002213 GO:0042098 ! positively regulates T cell proliferation [Term] id: GO:0042103 name: positive regulation of T cell homeostatic proliferation namespace: biological_process def: "Any process that activates or increases the rate or extent of resting T cell proliferation." [GOC:jl] synonym: "positive regulation of resting T cell proliferation" EXACT [] synonym: "positive regulation of T lymphocyte homeostatic proliferation" EXACT [] synonym: "positive regulation of T-cell homeostatic proliferation" EXACT [] synonym: "positive regulation of T-lymphocyte homeostatic proliferation" EXACT [] synonym: "up regulation of T cell homeostatic proliferation" EXACT [] synonym: "up-regulation of T cell homeostatic proliferation" EXACT [] synonym: "upregulation of T cell homeostatic proliferation" EXACT [] is_a: GO:0042102 ! positive regulation of T cell proliferation is_a: GO:0046013 ! regulation of T cell homeostatic proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001777 ! positively regulates T cell homeostatic proliferation relationship: RO:0002213 GO:0001777 ! positively regulates T cell homeostatic proliferation [Term] id: GO:0042110 name: T cell activation namespace: biological_process def: "The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific." [GOC:mgi_curators, ISBN:0781735149] synonym: "T lymphocyte activation" EXACT [] synonym: "T-cell activation" EXACT [] synonym: "T-lymphocyte activation" EXACT [] is_a: GO:0046649 ! lymphocyte activation intersection_of: GO:0001775 ! cell activation intersection_of: RO:0004009 CL:0000084 ! has primary input T cell relationship: RO:0004009 CL:0000084 ! has primary input T cell [Term] id: GO:0042118 name: endothelial cell activation namespace: biological_process def: "The change in morphology and behavior of an endothelial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor." [GOC:mgi_curators, ISBN:0781735149, PMID:12851652, PMID:14581484] is_a: GO:0001775 ! cell activation intersection_of: GO:0001775 ! cell activation intersection_of: RO:0004009 CL:0000115 ! has primary input endothelial cell relationship: RO:0004009 CL:0000115 ! has primary input endothelial cell [Term] id: GO:0042127 name: regulation of cell population proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell proliferation." [GOC:jl] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0008283 ! regulates (processual) cell population proliferation relationship: RO:0002211 GO:0008283 ! regulates (processual) cell population proliferation [Term] id: GO:0042129 name: regulation of T cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of T cell proliferation." [GOC:jl] synonym: "regulation of T lymphocyte proliferation" EXACT [] synonym: "regulation of T-cell proliferation" EXACT [] synonym: "regulation of T-lymphocyte proliferation" EXACT [] is_a: GO:0050670 ! regulation of lymphocyte proliferation is_a: GO:0050863 ! regulation of T cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0042098 ! regulates (processual) T cell proliferation relationship: RO:0002211 GO:0042098 ! regulates (processual) T cell proliferation [Term] id: GO:0042130 name: negative regulation of T cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of T cell proliferation." [GOC:jl] synonym: "down regulation of T cell proliferation" EXACT [] synonym: "down-regulation of T cell proliferation" EXACT [] synonym: "downregulation of T cell proliferation" EXACT [] synonym: "negative regulation of T lymphocyte proliferation" EXACT [] synonym: "negative regulation of T-cell proliferation" EXACT [] synonym: "negative regulation of T-lymphocyte proliferation" EXACT [] is_a: GO:0042129 ! regulation of T cell proliferation is_a: GO:0050672 ! negative regulation of lymphocyte proliferation is_a: GO:0050868 ! negative regulation of T cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0042098 ! negatively regulates T cell proliferation relationship: RO:0002212 GO:0042098 ! negatively regulates T cell proliferation [Term] id: GO:0042175 name: nuclear outer membrane-endoplasmic reticulum membrane network namespace: cellular_component def: "The continuous network of membranes encompassing the nuclear outer membrane and the endoplasmic reticulum membrane." [GOC:bf, GOC:jl, GOC:mah, GOC:mcc, GOC:pr, GOC:vw] synonym: "nuclear membrane-endoplasmic reticulum continuum" EXACT [GOC:mah] synonym: "nuclear membrane-ER network" EXACT [GOC:mah] is_a: GO:0016020 ! membrane relationship: BFO:0000050 GO:0012505 ! part of endomembrane system [Term] id: GO:0042176 name: regulation of protein catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds." [GOC:go_curators, GOC:jl] synonym: "regulation of cellular protein breakdown" EXACT [GOC:TermGenie] synonym: "regulation of cellular protein catabolic process" EXACT [] synonym: "regulation of cellular protein catabolism" EXACT [GOC:TermGenie] synonym: "regulation of cellular protein degradation" EXACT [GOC:TermGenie] synonym: "regulation of protein breakdown" EXACT [] synonym: "regulation of protein catabolism" EXACT [] synonym: "regulation of protein degradation" EXACT [] is_a: GO:0009894 ! regulation of catabolic process is_a: GO:0051246 ! regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030163 ! regulates (processual) protein catabolic process relationship: RO:0002211 GO:0030163 ! regulates (processual) protein catabolic process creation_date: 2014-08-21T15:05:45Z [Term] id: GO:0042177 name: negative regulation of protein catabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process." [GO_REF:0000058, GOC:kmv, GOC:obol, GOC:TermGenie, PMID:24785082] synonym: "down regulation of cellular protein breakdown" EXACT [GOC:TermGenie] synonym: "down regulation of cellular protein catabolic process" EXACT [GOC:TermGenie] synonym: "down regulation of cellular protein catabolism" EXACT [GOC:TermGenie] synonym: "down regulation of cellular protein degradation" EXACT [GOC:TermGenie] synonym: "down regulation of protein catabolic process" EXACT [] synonym: "down-regulation of cellular protein breakdown" EXACT [GOC:TermGenie] synonym: "down-regulation of cellular protein catabolic process" EXACT [GOC:TermGenie] synonym: "down-regulation of cellular protein catabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of cellular protein degradation" EXACT [GOC:TermGenie] synonym: "down-regulation of protein catabolic process" EXACT [] synonym: "downregulation of cellular protein breakdown" EXACT [GOC:TermGenie] synonym: "downregulation of cellular protein catabolic process" EXACT [GOC:TermGenie] synonym: "downregulation of cellular protein catabolism" EXACT [GOC:TermGenie] synonym: "downregulation of cellular protein degradation" EXACT [GOC:TermGenie] synonym: "downregulation of protein catabolic process" EXACT [] synonym: "negative regulation of cellular protein breakdown" EXACT [GOC:TermGenie] synonym: "negative regulation of cellular protein catabolic process" EXACT [] synonym: "negative regulation of cellular protein catabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of cellular protein degradation" EXACT [GOC:TermGenie] synonym: "negative regulation of protein breakdown" EXACT [] synonym: "negative regulation of protein catabolism" EXACT [] synonym: "negative regulation of protein degradation" EXACT [] is_a: GO:0009895 ! negative regulation of catabolic process is_a: GO:0042176 ! regulation of protein catabolic process is_a: GO:0051248 ! negative regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030163 ! negatively regulates protein catabolic process relationship: RO:0002212 GO:0030163 ! negatively regulates protein catabolic process [Term] id: GO:0042180 name: cellular ketone metabolic process namespace: biological_process def: "The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups." [GOC:jl, ISBN:0787650153] synonym: "ketone metabolism" EXACT [] is_a: GO:0044237 ! cellular metabolic process is_a: GO:0044281 ! small molecule metabolic process is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:17087 ! has primary input or output ketone relationship: RO:0004007 CHEBI:17087 ! has primary input or output ketone [Term] id: GO:0042181 name: ketone biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups." [GOC:go_curators] synonym: "ketone anabolism" EXACT [] synonym: "ketone biosynthesis" EXACT [] synonym: "ketone formation" EXACT [] synonym: "ketone synthesis" EXACT [] is_a: GO:0042180 ! cellular ketone metabolic process is_a: GO:0044249 ! cellular biosynthetic process is_a: GO:0044283 ! small molecule biosynthetic process is_a: GO:1901576 ! organic substance biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:17087 ! has primary output ketone relationship: RO:0004008 CHEBI:17087 ! has primary output ketone [Term] id: GO:0042182 name: ketone catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups." [GOC:go_curators] synonym: "ketone breakdown" EXACT [] synonym: "ketone catabolism" EXACT [] synonym: "ketone degradation" EXACT [] is_a: GO:0042180 ! cellular ketone metabolic process is_a: GO:0044248 ! cellular catabolic process is_a: GO:0044282 ! small molecule catabolic process is_a: GO:1901575 ! organic substance catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:17087 ! has primary input ketone relationship: RO:0004009 CHEBI:17087 ! has primary input ketone [Term] id: GO:0042221 name: response to chemical namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus." [GOC:jl] synonym: "response to chemical stimulus" EXACT [GOC:dos] synonym: "response to chemical substance" EXACT [] is_a: GO:0050896 ! response to stimulus intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:24431 ! has primary input chemical entity relationship: RO:0004009 CHEBI:24431 ! has primary input chemical entity [Term] id: GO:0042254 name: ribosome biogenesis namespace: biological_process def: "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis." [GOC:ma, PMID:26404467, Wikipedia:Ribosome_biogenesis] synonym: "ribosome biogenesis and assembly" EXACT [] is_a: GO:0022613 ! ribonucleoprotein complex biogenesis [Term] id: GO:0042255 name: ribosome assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of the mature ribosome and of its subunits." [GOC:ma, PMID:30467428] is_a: GO:0140694 ! non-membrane-bounded organelle assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0005840 ! results in assembly of ribosome relationship: BFO:0000050 GO:0042254 ! part of ribosome biogenesis relationship: RO:0002588 GO:0005840 ! results in assembly of ribosome [Term] id: GO:0042303 name: molting cycle namespace: biological_process def: "The periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin, etc." [GOC:jl, ISBN:0198506732] is_a: GO:0032501 ! multicellular organismal process [Term] id: GO:0042325 name: regulation of phosphorylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule." [GOC:jl] is_a: GO:0019220 ! regulation of phosphate metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0016310 ! regulates (processual) phosphorylation relationship: RO:0002211 GO:0016310 ! regulates (processual) phosphorylation [Term] id: GO:0042326 name: negative regulation of phosphorylation namespace: biological_process def: "Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule." [GOC:jl] synonym: "down regulation of phosphorylation" EXACT [] synonym: "down-regulation of phosphorylation" EXACT [] synonym: "downregulation of phosphorylation" EXACT [] is_a: GO:0042325 ! regulation of phosphorylation is_a: GO:0045936 ! negative regulation of phosphate metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0016310 ! negatively regulates phosphorylation relationship: RO:0002212 GO:0016310 ! negatively regulates phosphorylation [Term] id: GO:0042327 name: positive regulation of phosphorylation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule." [GOC:jl] synonym: "up regulation of phosphorylation" EXACT [] synonym: "up-regulation of phosphorylation" EXACT [] synonym: "upregulation of phosphorylation" EXACT [] is_a: GO:0042325 ! regulation of phosphorylation is_a: GO:0045937 ! positive regulation of phosphate metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0016310 ! positively regulates phosphorylation relationship: RO:0002213 GO:0016310 ! positively regulates phosphorylation [Term] id: GO:0042335 name: cuticle development namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of a cuticle, the outer layer of some animals and plants, which acts to prevent water loss." [ISBN:0192800825] synonym: "cuticle anabolism" EXACT [] synonym: "cuticle biosynthesis" EXACT [] synonym: "cuticle biosynthetic process" EXACT [] synonym: "cuticle formation" EXACT [] synonym: "cuticle synthesis" EXACT [] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001002 ! results in development of cuticle relationship: BFO:0000050 GO:0007275 ! part of multicellular organism development relationship: RO:0002296 UBERON:0001002 ! results in development of cuticle [Term] id: GO:0042337 name: cuticle development involved in chitin-based cuticle molting cycle namespace: biological_process def: "The synthesis and deposition of a chitin-based non-cellular, hardened, or membranous secretion from an epithelial sheet, occurring as part of the molting cycle. An example of this is found in Drosophila melanogaster." [GOC:dph, GOC:jl, GOC:mtg_sensu, GOC:tb] is_a: GO:0040003 ! chitin-based cuticle development intersection_of: GO:0042335 ! cuticle development intersection_of: BFO:0000050 GO:0007591 ! part of molting cycle, chitin-based cuticle relationship: BFO:0000050 GO:0007591 ! part of molting cycle, chitin-based cuticle [Term] id: GO:0042391 name: regulation of membrane potential namespace: biological_process def: "Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane." [GOC:jl, GOC:mtg_cardio, GOC:tb, ISBN:0198506732] is_a: BFO:0000003 ! occurrent relationship: BFO:0000051 GO:0034220 ! has part monoatomic ion transmembrane transport [Term] id: GO:0042401 name: biogenic amine biosynthetic process namespace: biological_process def: "The chemical reactions and pathways occurring at the level of individual cells resulting in the formation of any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters." [GOC:jl, ISBN:0395825172] synonym: "biogenic amine anabolism" EXACT [] synonym: "biogenic amine biosynthesis" EXACT [] synonym: "biogenic amine formation" EXACT [] synonym: "biogenic amine synthesis" EXACT [] synonym: "cellular biogenic amine biosynthetic process" EXACT [] is_a: GO:0006576 ! biogenic amine metabolic process is_a: GO:0009309 ! amine biosynthetic process [Term] id: GO:0042402 name: cellular biogenic amine catabolic process namespace: biological_process def: "The chemical reactions and pathways occurring at the level of individual cells resulting in the breakdown of biogenic amines, any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters." [GOC:go_curators, GOC:jl, ISBN:0198506732] synonym: "biogenic amine breakdown" EXACT [] synonym: "biogenic amine catabolism" EXACT [] synonym: "biogenic amine degradation" EXACT [] is_a: GO:0009310 ! amine catabolic process [Term] id: GO:0042415 name: norepinephrine metabolic process namespace: biological_process def: "The chemical reactions and pathways involving norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine." [GOC:jl, ISBN:0198506732] synonym: "levarterenol metabolic process" EXACT [] synonym: "levarterenol metabolism" EXACT [] synonym: "noradrenaline metabolic process" EXACT [] synonym: "noradrenaline metabolism" EXACT [] synonym: "norepinephrine metabolism" EXACT [] is_a: GO:0006807 ! nitrogen compound metabolic process is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:72587 ! has primary input or output (R)-noradrenaline(1+) relationship: RO:0004007 CHEBI:72587 ! has primary input or output (R)-noradrenaline(1+) [Term] id: GO:0042421 name: norepinephrine biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine." [GOC:jl, ISBN:0198506732] synonym: "levarterenol biosynthesis" EXACT [] synonym: "levarterenol biosynthetic process" EXACT [] synonym: "noradrenaline biosynthesis" EXACT [] synonym: "noradrenaline biosynthetic process" EXACT [] synonym: "norepinephrine anabolism" EXACT [] synonym: "norepinephrine biosynthesis" EXACT [] synonym: "norepinephrine formation" EXACT [] synonym: "norepinephrine synthesis" EXACT [] is_a: GO:0042415 ! norepinephrine metabolic process is_a: GO:1901576 ! organic substance biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:72587 ! has primary output (R)-noradrenaline(1+) relationship: RO:0004008 CHEBI:72587 ! has primary output (R)-noradrenaline(1+) [Term] id: GO:0042422 name: norepinephrine catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine." [GOC:jl, ISBN:0198506732] synonym: "levarterenol catabolic process" EXACT [] synonym: "levarterenol catabolism" EXACT [] synonym: "noradrenaline catabolic process" EXACT [] synonym: "noradrenaline catabolism" EXACT [] synonym: "norepinephrine breakdown" EXACT [] synonym: "norepinephrine catabolism" EXACT [] synonym: "norepinephrine degradation" EXACT [] xref: Wikipedia:Norepinephrine#Degradation is_a: GO:0042415 ! norepinephrine metabolic process is_a: GO:1901575 ! organic substance catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:72587 ! has primary input (R)-noradrenaline(1+) relationship: RO:0004009 CHEBI:72587 ! has primary input (R)-noradrenaline(1+) [Term] id: GO:0042423 name: catecholamine biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." [GOC:jl, ISBN:0198506732] synonym: "catecholamine anabolism" EXACT [] synonym: "catecholamine biosynthesis" EXACT [] synonym: "catecholamine formation" EXACT [] synonym: "catecholamine synthesis" EXACT [] xref: Wikipedia:Catecholamines is_a: GO:0006584 ! catecholamine metabolic process is_a: GO:0009713 ! catechol-containing compound biosynthetic process is_a: GO:0042401 ! biogenic amine biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:33567 ! has primary output catecholamine relationship: RO:0004008 CHEBI:33567 ! has primary output catecholamine [Term] id: GO:0042424 name: catecholamine catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." [GOC:jl, ISBN:0198506732] synonym: "catecholamine breakdown" EXACT [] synonym: "catecholamine catabolism" EXACT [] synonym: "catecholamine degradation" EXACT [] is_a: GO:0006584 ! catecholamine metabolic process is_a: GO:0019614 ! catechol-containing compound catabolic process is_a: GO:0042402 ! cellular biogenic amine catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:33567 ! has primary input catecholamine relationship: RO:0004009 CHEBI:33567 ! has primary input catecholamine [Term] id: GO:0042427 name: serotonin biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties." [GOC:jl, ISBN:0198506732] synonym: "serotonin anabolism" EXACT [] synonym: "serotonin biosynthesis" EXACT [] synonym: "serotonin formation" EXACT [] synonym: "serotonin synthesis" EXACT [] xref: Wikipedia:Serotonin is_a: GO:0009058 ! biosynthetic process is_a: GO:0042428 ! serotonin metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:350546 ! has primary output serotonin(1+) relationship: RO:0004008 CHEBI:350546 ! has primary output serotonin(1+) [Term] id: GO:0042428 name: serotonin metabolic process namespace: biological_process def: "The chemical reactions and pathways involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties." [GOC:jl, ISBN:0198506732] synonym: "serotonin metabolism" EXACT [] is_a: GO:0018958 ! phenol-containing compound metabolic process is_a: GO:0042430 ! indole-containing compound metabolic process is_a: GO:0097164 ! ammonium ion metabolic process is_a: GO:1901160 ! primary amino compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:350546 ! has primary input or output serotonin(1+) relationship: RO:0004007 CHEBI:350546 ! has primary input or output serotonin(1+) [Term] id: GO:0042429 name: serotonin catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties." [GOC:jl, ISBN:0198506732] synonym: "serotonin breakdown" EXACT [] synonym: "serotonin catabolism" EXACT [] synonym: "serotonin degradation" EXACT [] is_a: GO:0009056 ! catabolic process is_a: GO:0042428 ! serotonin metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:350546 ! has primary input serotonin(1+) relationship: RO:0004009 CHEBI:350546 ! has primary input serotonin(1+) [Term] id: GO:0042430 name: indole-containing compound metabolic process namespace: biological_process def: "The chemical reactions and pathways involving compounds that contain an indole (2,3-benzopyrrole) skeleton." [GOC:jl, GOC:mah] synonym: "indole and derivative metabolic process" EXACT [] synonym: "indole and derivative metabolism" EXACT [] synonym: "indole-containing compound metabolism" EXACT [] synonym: "ketole metabolic process" EXACT [] synonym: "ketole metabolism" EXACT [] is_a: GO:0006725 ! cellular aromatic compound metabolic process is_a: GO:0034641 ! cellular nitrogen compound metabolic process is_a: GO:0046483 ! heterocycle metabolic process is_a: GO:1901360 ! organic cyclic compound metabolic process is_a: GO:1901564 ! organonitrogen compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:24828 ! has primary input or output indoles relationship: RO:0004007 CHEBI:24828 ! has primary input or output indoles [Term] id: GO:0042435 name: indole-containing compound biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of compounds that contain an indole (2,3-benzopyrrole) skeleton." [GOC:jl] synonym: "indole derivative biosynthesis" EXACT [] synonym: "indole derivative biosynthetic process" EXACT [] synonym: "indole-containing compound anabolism" EXACT [] synonym: "indole-containing compound biosynthesis" EXACT [] synonym: "indole-containing compound formation" EXACT [] synonym: "indole-containing compound synthesis" EXACT [] is_a: GO:0018130 ! heterocycle biosynthetic process is_a: GO:0019438 ! aromatic compound biosynthetic process is_a: GO:0042430 ! indole-containing compound metabolic process is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process is_a: GO:1901362 ! organic cyclic compound biosynthetic process is_a: GO:1901566 ! organonitrogen compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:24828 ! has primary output indoles relationship: RO:0004008 CHEBI:24828 ! has primary output indoles [Term] id: GO:0042436 name: indole-containing compound catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of compounds that contain an indole (2,3-benzopyrrole) skeleton." [GOC:jl] synonym: "indole derivative catabolic process" EXACT [] synonym: "indole derivative catabolism" EXACT [] synonym: "indole-containing compound breakdown" EXACT [] synonym: "indole-containing compound catabolism" EXACT [] synonym: "indole-containing compound degradation" EXACT [] is_a: GO:0019439 ! aromatic compound catabolic process is_a: GO:0042430 ! indole-containing compound metabolic process is_a: GO:0044270 ! cellular nitrogen compound catabolic process is_a: GO:0046700 ! heterocycle catabolic process is_a: GO:1901361 ! organic cyclic compound catabolic process is_a: GO:1901565 ! organonitrogen compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:24828 ! has primary input indoles relationship: RO:0004009 CHEBI:24828 ! has primary input indoles [Term] id: GO:0042461 name: photoreceptor cell development namespace: biological_process def: "Development of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light." [GOC:go_curators] synonym: "photoreceptor morphogenesis" EXACT [] is_a: GO:0048666 ! neuron development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000210 ! results in development of photoreceptor cell relationship: BFO:0000050 GO:0046530 ! part of photoreceptor cell differentiation relationship: RO:0002296 CL:0000210 ! results in development of photoreceptor cell [Term] id: GO:0042462 name: eye photoreceptor cell development namespace: biological_process def: "Development of a photoreceptor, a sensory cell in the eye that reacts to the presence of light. They usually contain a pigment that undergoes a chemical change when light is absorbed, thus stimulating a nerve." [GOC:jl, ISBN:0192800981] is_a: GO:0042461 ! photoreceptor cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000287 ! results in development of eye photoreceptor cell relationship: BFO:0000050 GO:0001754 ! part of eye photoreceptor cell differentiation relationship: RO:0002296 CL:0000287 ! results in development of eye photoreceptor cell [Term] id: GO:0042478 name: regulation of eye photoreceptor cell development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of eye photoreceptor development." [GOC:jl] synonym: "regulation of eye photoreceptor development" EXACT [] is_a: GO:0046532 ! regulation of photoreceptor cell differentiation is_a: GO:0060284 ! regulation of cell development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0042462 ! regulates (processual) eye photoreceptor cell development relationship: RO:0002211 GO:0042462 ! regulates (processual) eye photoreceptor cell development [Term] id: GO:0042479 name: positive regulation of eye photoreceptor cell development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of eye photoreceptor development." [GOC:jl] synonym: "positive regulation of eye photoreceptor development" EXACT [] synonym: "up regulation of eye photoreceptor cell development" EXACT [] synonym: "up-regulation of eye photoreceptor cell development" EXACT [] synonym: "upregulation of eye photoreceptor cell development" EXACT [] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0042478 ! regulation of eye photoreceptor cell development is_a: GO:0046534 ! positive regulation of photoreceptor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0042462 ! positively regulates eye photoreceptor cell development relationship: RO:0002213 GO:0042462 ! positively regulates eye photoreceptor cell development [Term] id: GO:0042480 name: negative regulation of eye photoreceptor cell development namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of eye photoreceptor development." [GOC:jl] synonym: "down regulation of eye photoreceptor cell development" EXACT [] synonym: "down-regulation of eye photoreceptor cell development" EXACT [] synonym: "downregulation of eye photoreceptor cell development" EXACT [] synonym: "negative regulation of eye photoreceptor development" EXACT [] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0042478 ! regulation of eye photoreceptor cell development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0042462 ! negatively regulates eye photoreceptor cell development relationship: RO:0002212 GO:0042462 ! negatively regulates eye photoreceptor cell development [Term] id: GO:0042551 name: neuron maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for a neuron to attain its fully functional state." [GOC:dph, GOC:jl] is_a: GO:0048469 ! cell maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 CL:0000540 ! results in maturation of neuron relationship: BFO:0000050 GO:0048666 ! part of neuron development relationship: RO:0002299 CL:0000540 ! results in maturation of neuron [Term] id: GO:0042588 name: zymogen granule namespace: cellular_component def: "A membrane-bounded, cytoplasmic secretory granule found in enzyme-secreting cells and visible by light microscopy. Contain zymogen, an inactive enzyme precursor, often of a digestive enzyme." [GOC:jl, ISBN:0198506732] is_a: GO:0030141 ! secretory granule [Term] id: GO:0042589 name: zymogen granule membrane namespace: cellular_component def: "The lipid bilayer surrounding a zymogen granule." [GOC:jl] is_a: GO:0030667 ! secretory granule membrane intersection_of: GO:0016020 ! membrane intersection_of: RO:0002007 GO:0042588 ! bounding layer of zymogen granule relationship: RO:0002007 GO:0042588 ! bounding layer of zymogen granule [Term] id: GO:0042592 name: homeostatic process namespace: biological_process def: "Any biological process involved in the maintenance of an internal steady state." [GOC:jl, ISBN:0395825172] synonym: "homeostasis" EXACT [] is_a: GO:0008150 ! biological_process [Term] id: GO:0042611 name: MHC protein complex namespace: cellular_component def: "A transmembrane protein complex composed of an MHC alpha chain and, in most cases, either an MHC class II beta chain or an invariant beta2-microglobin chain, and with or without a bound peptide, lipid, or polysaccharide antigen." [GOC:add, GOC:jl, ISBN:0781735149, PMID:15928678, PMID:16153240] is_a: GO:0098797 ! plasma membrane protein complex [Term] id: GO:0042613 name: MHC class II protein complex namespace: cellular_component def: "A transmembrane protein complex composed of an MHC class II alpha and MHC class II beta chain, and with or without a bound peptide or polysaccharide antigen." [GOC:add, GOC:jl, ISBN:0120781859, PMID:15928678] is_a: GO:0042611 ! MHC protein complex [Term] id: GO:0042641 name: actomyosin namespace: cellular_component def: "Any complex of actin, myosin, and accessory proteins." [GOC:go_curators] synonym: "actomyosin complex" EXACT [] synonym: "actomyosin structure" EXACT [] is_a: GO:0110165 ! cellular anatomical entity relationship: BFO:0000050 GO:0015629 ! part of actin cytoskeleton [Term] id: GO:0042670 name: retinal cone cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized features of a retinal cone cell." [GOC:go_curators] is_a: GO:0060219 ! camera-type eye photoreceptor cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000573 ! results in acquisition of features of retinal cone cell relationship: RO:0002315 CL:0000573 ! results in acquisition of features of retinal cone cell [Term] id: GO:0042692 name: muscle cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a muscle cell." [CL:0000187, GOC:go_curators] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000187 ! results in acquisition of features of muscle cell relationship: BFO:0000050 GO:0061061 ! part of muscle structure development relationship: RO:0002315 CL:0000187 ! results in acquisition of features of muscle cell [Term] id: GO:0042698 name: ovulation cycle namespace: biological_process def: "The type of sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years." [ISBN:0721662544] is_a: GO:0048511 ! rhythmic process is_a: GO:0048609 ! multicellular organismal reproductive process relationship: RO:0002160 NCBITaxon:2759 ! only in taxon Eukaryota relationship: RO:0002162 NCBITaxon:2759 {all_only="true"} ! in taxon Eukaryota [Term] id: GO:0042702 name: uterine wall growth namespace: biological_process def: "The regrowth of the endometrium and blood vessels in the uterus following menstruation, resulting from a rise in progesterone levels." [GOC:jl] is_a: GO:0022602 ! ovulation cycle process is_a: GO:0048589 ! developmental growth intersection_of: GO:0040007 ! growth intersection_of: RO:0002343 UBERON:0000459 ! results in growth of uterine wall relationship: BFO:0000050 GO:0001553 ! part of luteinization relationship: RO:0002343 UBERON:0000459 ! results in growth of uterine wall [Term] id: GO:0042713 name: sperm ejaculation namespace: biological_process def: "The expulsion of seminal fluid, thick white fluid containing spermatozoa, from the male genital tract." [GOC:jl, http://www.cogsci.princeton.edu/~wn/] is_a: GO:0048609 ! multicellular organismal reproductive process relationship: BFO:0000050 GO:0007320 ! part of insemination [Term] id: GO:0042742 name: defense response to bacterium namespace: biological_process def: "Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism." [GOC:jl] synonym: "defence response to bacteria" EXACT [] synonym: "defence response to bacterium" EXACT [] synonym: "defense response to bacteria" EXACT [] is_a: GO:0009617 ! response to bacterium is_a: GO:0098542 ! defense response to other organism intersection_of: GO:0006952 ! defense response intersection_of: RO:0004009 NCBITaxon:2 ! has primary input Bacteria [Term] id: GO:0042762 name: regulation of sulfur metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur, the nonmetallic element sulfur or compounds that contain sulfur." [GOC:go_curators] synonym: "regulation of sulfur metabolism" EXACT [] synonym: "regulation of sulphur metabolic process" EXACT [] synonym: "regulation of sulphur metabolism" EXACT [] is_a: GO:0031323 ! regulation of cellular metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006790 ! regulates (processual) sulfur compound metabolic process relationship: RO:0002211 GO:0006790 ! regulates (processual) sulfur compound metabolic process [Term] id: GO:0042886 name: amide transport namespace: biological_process def: "The directed movement of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl, ISBN:0198506732] is_a: GO:0071705 ! nitrogen compound transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:32988 ! has primary input amide relationship: RO:0004009 CHEBI:32988 ! has primary input amide [Term] id: GO:0042887 name: amide transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, from one side of a membrane to the other." [GOC:jl, ISBN:0198506732] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:32988 ! has primary input amide relationship: BFO:0000050 GO:0042886 ! part of amide transport relationship: RO:0004009 CHEBI:32988 ! has primary input amide [Term] id: GO:0042981 name: regulation of apoptotic process namespace: biological_process def: "Any process that modulates the occurrence or rate of cell death by apoptotic process." [GOC:jl, GOC:mtg_apoptosis] is_a: GO:0043067 ! regulation of programmed cell death intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006915 ! regulates (processual) apoptotic process relationship: RO:0002211 GO:0006915 ! regulates (processual) apoptotic process [Term] id: GO:0042995 name: cell projection namespace: cellular_component def: "A prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, http://www.cogsci.princeton.edu/~wn/] synonym: "cellular projection" EXACT [] is_a: GO:0110165 ! cellular anatomical entity relationship: BFO:0000050 CL:0000000 ! part of cell [Term] id: GO:0042996 name: regulation of Golgi to plasma membrane protein transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane." [GOC:jl] is_a: GO:0051223 ! regulation of protein transport is_a: GO:0060627 ! regulation of vesicle-mediated transport is_a: GO:1903076 ! regulation of protein localization to plasma membrane intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0043001 ! regulates (processual) Golgi to plasma membrane protein transport relationship: RO:0002211 GO:0043001 ! regulates (processual) Golgi to plasma membrane protein transport [Term] id: GO:0042997 name: negative regulation of Golgi to plasma membrane protein transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane." [GOC:jl] synonym: "down regulation of Golgi to plasma membrane protein transport" EXACT [] synonym: "down-regulation of Golgi to plasma membrane protein transport" EXACT [] synonym: "downregulation of Golgi to plasma membrane protein transport" EXACT [] is_a: GO:0042996 ! regulation of Golgi to plasma membrane protein transport is_a: GO:0051224 ! negative regulation of protein transport is_a: GO:1903077 ! negative regulation of protein localization to plasma membrane intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0043001 ! negatively regulates Golgi to plasma membrane protein transport relationship: RO:0002212 GO:0043001 ! negatively regulates Golgi to plasma membrane protein transport [Term] id: GO:0042998 name: positive regulation of Golgi to plasma membrane protein transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane." [GOC:jl] synonym: "up regulation of Golgi to plasma membrane protein transport" EXACT [] synonym: "up-regulation of Golgi to plasma membrane protein transport" EXACT [] synonym: "upregulation of Golgi to plasma membrane protein transport" EXACT [] is_a: GO:0042996 ! regulation of Golgi to plasma membrane protein transport is_a: GO:0051222 ! positive regulation of protein transport is_a: GO:1903078 ! positive regulation of protein localization to plasma membrane intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0043001 ! positively regulates Golgi to plasma membrane protein transport relationship: RO:0002213 GO:0043001 ! positively regulates Golgi to plasma membrane protein transport [Term] id: GO:0043001 name: Golgi to plasma membrane protein transport namespace: biological_process def: "The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane." [ISBN:0716731363] is_a: GO:0006893 ! Golgi to plasma membrane transport is_a: GO:0015031 ! protein transport is_a: GO:0061951 ! establishment of protein localization to plasma membrane is_a: GO:0072659 ! protein localization to plasma membrane intersection_of: GO:0015031 ! protein transport intersection_of: RO:0002338 GO:0005794 ! has target start location Golgi apparatus intersection_of: RO:0002339 GO:0005886 ! has target end location plasma membrane intersection_of: RO:0002608 GO:0031982 ! process has causal agent vesicle [Term] id: GO:0043005 name: neuron projection namespace: cellular_component def: "A prolongation or process extending from a nerve cell, e.g. an axon or dendrite." [GOC:jl, http://www.cogsci.princeton.edu/~wn/] synonym: "neuron process" EXACT [] synonym: "neuron protrusion" EXACT [NIF_Subcellular:sao250931889] synonym: "neuronal cell projection" EXACT [] xref: NIF_Subcellular:sao867568886 is_a: GO:0120025 ! plasma membrane bounded cell projection intersection_of: GO:0120025 ! plasma membrane bounded cell projection intersection_of: BFO:0000050 CL:0000540 ! part of neuron relationship: BFO:0000050 CL:0000540 ! part of neuron [Term] id: GO:0043009 name: chordate embryonic development namespace: biological_process def: "The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching." [GOC:mtg_sensu] is_a: GO:0009792 ! embryo development ending in birth or egg hatching relationship: RO:0002160 NCBITaxon:7711 ! only in taxon Chordata relationship: RO:0002162 NCBITaxon:7711 {all_only="true"} ! in taxon Chordata [Term] id: GO:0043010 name: camera-type eye development namespace: biological_process def: "The process whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field." [GOC:go_curators, GOC:mtg_sensu] is_a: GO:0001654 ! eye development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000019 ! results in development of camera-type eye relationship: RO:0002296 UBERON:0000019 ! results in development of camera-type eye [Term] id: GO:0043025 name: neuronal cell body namespace: cellular_component def: "The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites." [GOC:go_curators] synonym: "neuron cell body" EXACT [] synonym: "neuronal cell soma" EXACT [] xref: NIF_Subcellular:sao1044911821 xref: Wikipedia:Soma_(biology) is_a: GO:0044297 ! cell body intersection_of: GO:0044297 ! cell body intersection_of: BFO:0000050 CL:0000540 ! part of neuron relationship: BFO:0000050 GO:0036477 ! part of somatodendritic compartment [Term] id: GO:0043029 name: T cell homeostasis namespace: biological_process def: "The process of regulating the proliferation and elimination of T cells such that the total number of T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus." [GOC:mgi_curators, ISBN:0781735149] synonym: "T lymphocyte homeostasis" EXACT [] synonym: "T-cell homeostasis" EXACT [] synonym: "T-lymphocyte homeostasis" EXACT [] is_a: GO:0002260 ! lymphocyte homeostasis intersection_of: GO:0048872 ! homeostasis of number of cells intersection_of: RO:0012003 CL:0000084 ! acts on population of T cell relationship: RO:0012003 CL:0000084 ! acts on population of T cell [Term] id: GO:0043043 name: peptide biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. This may include the translation of a precursor protein and its subsequent processing into a functional peptide." [GOC:dph, GOC:jl] synonym: "peptide anabolism" EXACT [] synonym: "peptide biosynthesis" EXACT [] synonym: "peptide formation" EXACT [] synonym: "peptide synthesis" EXACT [] is_a: GO:0006518 ! peptide metabolic process is_a: GO:0043604 ! amide biosynthetic process is_a: GO:1901566 ! organonitrogen compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:16670 ! has primary output peptide relationship: RO:0004008 CHEBI:16670 ! has primary output peptide [Term] id: GO:0043062 name: extracellular structure organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures in the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane, and also covers the host cell environment outside an intracellular parasite." [GOC:ai, GOC:dph, GOC:jl, GOC:mah] synonym: "extracellular structure organisation" EXACT [] synonym: "extracellular structure organization and biogenesis" EXACT [GOC:dph, GOC:jl, GOC:mah] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0005576 ! results in organization of extracellular region relationship: RO:0002592 GO:0005576 ! results in organization of extracellular region [Term] id: GO:0043065 name: positive regulation of apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process." [GOC:jl, GOC:mtg_apoptosis] synonym: "up regulation of apoptosis" EXACT [] synonym: "up-regulation of apoptosis" EXACT [] synonym: "upregulation of apoptosis" EXACT [] is_a: GO:0042981 ! regulation of apoptotic process is_a: GO:0043068 ! positive regulation of programmed cell death intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006915 ! positively regulates apoptotic process relationship: RO:0002213 GO:0006915 ! positively regulates apoptotic process [Term] id: GO:0043066 name: negative regulation of apoptotic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process." [GOC:jl, GOC:mtg_apoptosis] synonym: "anti-apoptosis" EXACT [] synonym: "down regulation of apoptosis" EXACT [] synonym: "down-regulation of apoptosis" EXACT [] synonym: "downregulation of apoptosis" EXACT [] is_a: GO:0042981 ! regulation of apoptotic process is_a: GO:0043069 ! negative regulation of programmed cell death intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006915 ! negatively regulates apoptotic process relationship: RO:0002212 GO:0006915 ! negatively regulates apoptotic process [Term] id: GO:0043067 name: regulation of programmed cell death namespace: biological_process def: "Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes." [GOC:jl] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0012501 ! regulates (processual) programmed cell death relationship: RO:0002211 GO:0012501 ! regulates (processual) programmed cell death [Term] id: GO:0043068 name: positive regulation of programmed cell death namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes." [GOC:jl] synonym: "up regulation of programmed cell death" EXACT [] synonym: "up-regulation of programmed cell death" EXACT [] synonym: "upregulation of programmed cell death" EXACT [] is_a: GO:0043067 ! regulation of programmed cell death is_a: GO:0048522 ! positive regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0012501 ! positively regulates programmed cell death relationship: RO:0002213 GO:0012501 ! positively regulates programmed cell death [Term] id: GO:0043069 name: negative regulation of programmed cell death namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes." [GOC:jl] synonym: "down regulation of programmed cell death" EXACT [] synonym: "down-regulation of programmed cell death" EXACT [] synonym: "downregulation of programmed cell death" EXACT [] is_a: GO:0043067 ! regulation of programmed cell death is_a: GO:0048523 ! negative regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0012501 ! negatively regulates programmed cell death relationship: RO:0002212 GO:0012501 ! negatively regulates programmed cell death [Term] id: GO:0043073 name: germ cell nucleus namespace: cellular_component def: "The nucleus of a germ cell, a reproductive cell in multicellular organisms." [CL:0000586, GOC:go_curators] synonym: "germ-cell nucleus" EXACT [] is_a: GO:0005634 ! nucleus intersection_of: GO:0005634 ! nucleus intersection_of: BFO:0000050 CL:0000586 ! part of germ cell relationship: BFO:0000050 CL:0000586 ! part of germ cell [Term] id: GO:0043085 name: positive regulation of catalytic activity namespace: biological_process def: "Any process that activates or increases the activity of an enzyme." [GOC:ebc, GOC:jl, GOC:tb, GOC:vw] synonym: "positive regulation of enzyme activity" EXACT [GOC:tb] synonym: "up regulation of enzyme activity" EXACT [] synonym: "up-regulation of enzyme activity" EXACT [] synonym: "upregulation of enzyme activity" EXACT [] is_a: GO:0044093 ! positive regulation of molecular function is_a: GO:0050790 ! regulation of catalytic activity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0003824 ! positively regulates catalytic activity relationship: RO:0002213 GO:0003824 ! positively regulates catalytic activity [Term] id: GO:0043086 name: negative regulation of catalytic activity namespace: biological_process def: "Any process that stops or reduces the activity of an enzyme." [GOC:ebc, GOC:jl, GOC:tb, GOC:vw] synonym: "down regulation of enzyme activity" EXACT [] synonym: "down-regulation of enzyme activity" EXACT [] synonym: "down-regulation of metalloenzyme activity" EXACT [] synonym: "downregulation of enzyme activity" EXACT [] synonym: "negative regulation of enzyme activity" EXACT [GOC:tb] is_a: GO:0044092 ! negative regulation of molecular function is_a: GO:0050790 ! regulation of catalytic activity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0003824 ! negatively regulates catalytic activity relationship: RO:0002212 GO:0003824 ! negatively regulates catalytic activity [Term] id: GO:0043133 name: hindgut contraction namespace: biological_process def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the hindgut. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The hindgut is the posterior part of the alimentary canal, including the rectum, and the large intestine." [GOC:jl, GOC:mtg_muscle, UBERON:0001046] is_a: GO:0006939 ! smooth muscle contraction is_a: GO:0022600 ! digestive system process intersection_of: GO:0006939 ! smooth muscle contraction intersection_of: BFO:0000066 UBERON:0001046 ! occurs in hindgut relationship: BFO:0000066 UBERON:0001046 ! occurs in hindgut [Term] id: GO:0043134 name: regulation of hindgut contraction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine." [GOC:jl, UBERON:0001046] is_a: GO:0006940 ! regulation of smooth muscle contraction is_a: GO:0044058 ! regulation of digestive system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0043133 ! regulates (processual) hindgut contraction relationship: RO:0002211 GO:0043133 ! regulates (processual) hindgut contraction [Term] id: GO:0043143 name: regulation of translation by machinery localization namespace: biological_process def: "Any process in which proteins and protein complexes involved in translation are transported to, or maintained in, a specific location." [GOC:jl] synonym: "establishment and maintenance of translational machinery localization" EXACT [] synonym: "establishment and maintenance of translational protein localization" EXACT [] synonym: "regulation of translation by machinery localisation" EXACT [GOC:mah] synonym: "translational machinery localization" EXACT [GOC:dph, GOC:tb] synonym: "translational protein localization" EXACT [] is_a: GO:0006417 ! regulation of translation is_a: GO:0008104 ! protein localization intersection_of: GO:0008104 ! protein localization intersection_of: BFO:0000050 GO:0006412 ! part of translation relationship: BFO:0000050 GO:0006412 ! part of translation [Term] id: GO:0043170 name: macromolecule metabolic process namespace: biological_process namespace: protein def: "The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:mah] synonym: "biopolymer metabolic process" EXACT [GOC:mtg_chebi_dec09] synonym: "macromolecule metabolism" EXACT [] synonym: "organismal macromolecule metabolism" EXACT [] is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:33694 ! has primary input or output biomacromolecule relationship: RO:0004007 CHEBI:33694 ! has primary input or output biomacromolecule [Term] id: GO:0043171 name: peptide catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another." [GOC:jl] synonym: "peptide breakdown" EXACT [] synonym: "peptide catabolism" EXACT [] synonym: "peptide degradation" EXACT [] is_a: GO:0006518 ! peptide metabolic process is_a: GO:0044248 ! cellular catabolic process is_a: GO:1901565 ! organonitrogen compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:16670 ! has primary input peptide relationship: RO:0004009 CHEBI:16670 ! has primary input peptide [Term] id: GO:0043200 name: response to amino acid namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups." [GOC:ef, GOC:mlg] synonym: "response to amino acid stimulus" EXACT [GOC:dos] is_a: GO:0001101 ! response to acid chemical is_a: GO:0010243 ! response to organonitrogen compound is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:33709 ! has primary input amino acid relationship: RO:0004009 CHEBI:33709 ! has primary input amino acid [Term] id: GO:0043207 name: response to external biotic stimulus namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things." [GOC:go_curators] is_a: GO:0009605 ! response to external stimulus is_a: GO:0009607 ! response to biotic stimulus [Term] id: GO:0043226 name: organelle namespace: cellular_component def: "Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane." [GOC:go_curators] xref: NIF_Subcellular:sao1539965131 xref: Wikipedia:Organelle is_a: GO:0110165 ! cellular anatomical entity [Term] id: GO:0043227 name: membrane-bounded organelle namespace: cellular_component def: "Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane." [GOC:go_curators] synonym: "membrane-enclosed organelle" EXACT [] xref: NIF_Subcellular:sao414196390 is_a: GO:0043226 ! organelle intersection_of: GO:0043226 ! organelle intersection_of: BFO:0000051 GO:0016020 ! has part membrane disjoint_from: GO:0043228 ! non-membrane-bounded organelle relationship: BFO:0000051 GO:0016020 ! has part membrane [Term] id: GO:0043228 name: non-membrane-bounded organelle namespace: cellular_component def: "Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes." [GOC:go_curators] synonym: "non-membrane-enclosed organelle" EXACT [] xref: NIF_Subcellular:sao1456184038 is_a: GO:0043226 ! organelle [Term] id: GO:0043229 name: intracellular organelle namespace: cellular_component def: "Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane." [GOC:go_curators] is_a: GO:0043226 ! organelle intersection_of: GO:0043226 ! organelle intersection_of: BFO:0000050 GO:0005622 ! part of intracellular anatomical structure disjoint_from: GO:0043230 ! extracellular organelle relationship: BFO:0000050 GO:0005622 ! part of intracellular anatomical structure [Term] id: GO:0043230 name: extracellular organelle namespace: cellular_component def: "Organized structure of distinctive morphology and function, occurring outside the cell. Includes, for example, extracellular membrane vesicles (EMVs) and the cellulosomes of anaerobic bacteria and fungi." [GOC:jl, PMID:9914479] is_a: GO:0043226 ! organelle intersection_of: GO:0043226 ! organelle intersection_of: BFO:0000050 GO:0005576 ! part of extracellular region relationship: BFO:0000050 GO:0005576 ! part of extracellular region [Term] id: GO:0043231 name: intracellular membrane-bounded organelle namespace: cellular_component def: "Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane." [GOC:go_curators] synonym: "intracellular membrane-enclosed organelle" EXACT [] is_a: GO:0043227 ! membrane-bounded organelle is_a: GO:0043229 ! intracellular organelle intersection_of: GO:0043227 ! membrane-bounded organelle intersection_of: BFO:0000050 GO:0005622 ! part of intracellular anatomical structure [Term] id: GO:0043232 name: intracellular non-membrane-bounded organelle namespace: cellular_component def: "Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes." [GOC:go_curators] synonym: "intracellular non-membrane-enclosed organelle" EXACT [] is_a: GO:0043228 ! non-membrane-bounded organelle is_a: GO:0043229 ! intracellular organelle intersection_of: GO:0043228 ! non-membrane-bounded organelle intersection_of: BFO:0000050 GO:0005622 ! part of intracellular anatomical structure [Term] id: GO:0043233 name: organelle lumen namespace: cellular_component def: "The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen." [GOC:jl, GOC:mah] is_a: GO:0031974 ! membrane-enclosed lumen intersection_of: GO:0031974 ! membrane-enclosed lumen intersection_of: BFO:0000050 GO:0043226 ! part of organelle relationship: BFO:0000050 GO:0043226 ! part of organelle [Term] id: GO:0043242 name: negative regulation of protein-containing complex disassembly namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components." [GOC:jl] synonym: "down regulation of protein complex disassembly" EXACT [] synonym: "down-regulation of protein complex disassembly" EXACT [] synonym: "downregulation of protein complex disassembly" EXACT [] is_a: GO:0043244 ! regulation of protein-containing complex disassembly is_a: GO:0051129 ! negative regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0032984 ! negatively regulates protein-containing complex disassembly relationship: RO:0002212 GO:0032984 ! negatively regulates protein-containing complex disassembly [Term] id: GO:0043243 name: positive regulation of protein-containing complex disassembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components." [GOC:jl] synonym: "up regulation of protein complex disassembly" EXACT [] synonym: "up-regulation of protein complex disassembly" EXACT [] synonym: "upregulation of protein complex disassembly" EXACT [] is_a: GO:0043244 ! regulation of protein-containing complex disassembly is_a: GO:0051130 ! positive regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0032984 ! positively regulates protein-containing complex disassembly relationship: RO:0002213 GO:0032984 ! positively regulates protein-containing complex disassembly [Term] id: GO:0043244 name: regulation of protein-containing complex disassembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components." [GOC:jl] is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0032984 ! regulates (processual) protein-containing complex disassembly relationship: RO:0002211 GO:0032984 ! regulates (processual) protein-containing complex disassembly [Term] id: GO:0043249 name: erythrocyte maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for an erythrocyte to attain its fully functional state." [GOC:devbiol, GOC:jl] synonym: "RBC maturation" EXACT [CL:0000232] synonym: "red blood cell maturation" EXACT [CL:0000232] is_a: GO:0048469 ! cell maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 CL:0000232 ! results in maturation of erythrocyte relationship: BFO:0000050 GO:0048821 ! part of erythrocyte development relationship: RO:0002299 CL:0000232 ! results in maturation of erythrocyte [Term] id: GO:0043254 name: regulation of protein-containing complex assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein complex assembly." [GOC:jl] is_a: GO:0044087 ! regulation of cellular component biogenesis is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0065003 ! regulates (processual) protein-containing complex assembly relationship: RO:0002211 GO:0065003 ! regulates (processual) protein-containing complex assembly [Term] id: GO:0043255 name: regulation of carbohydrate biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of carbohydrates." [GOC:jl] synonym: "regulation of carbohydrate anabolism" EXACT [] synonym: "regulation of carbohydrate biosynthesis" EXACT [] synonym: "regulation of carbohydrate formation" EXACT [] synonym: "regulation of carbohydrate synthesis" EXACT [] is_a: GO:0006109 ! regulation of carbohydrate metabolic process is_a: GO:0009889 ! regulation of biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0016051 ! regulates (processual) carbohydrate biosynthetic process relationship: RO:0002211 GO:0016051 ! regulates (processual) carbohydrate biosynthetic process [Term] id: GO:0043264 name: extracellular non-membrane-bounded organelle namespace: cellular_component def: "Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring outside the cell." [GOC:jl] synonym: "extracellular non-membrane-enclosed organelle" EXACT [] is_a: GO:0043228 ! non-membrane-bounded organelle is_a: GO:0043230 ! extracellular organelle intersection_of: GO:0043228 ! non-membrane-bounded organelle intersection_of: BFO:0000050 GO:0005576 ! part of extracellular region [Term] id: GO:0043269 name: regulation of monoatomic ion transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl] is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006811 ! regulates (processual) monoatomic ion transport relationship: RO:0002211 GO:0006811 ! regulates (processual) monoatomic ion transport [Term] id: GO:0043270 name: positive regulation of monoatomic ion transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl] synonym: "up regulation of ion transport" EXACT [] synonym: "up-regulation of ion transport" EXACT [] synonym: "upregulation of ion transport" EXACT [] is_a: GO:0043269 ! regulation of monoatomic ion transport is_a: GO:0051050 ! positive regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006811 ! positively regulates monoatomic ion transport relationship: RO:0002213 GO:0006811 ! positively regulates monoatomic ion transport [Term] id: GO:0043271 name: negative regulation of monoatomic ion transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl] synonym: "down regulation of ion transport" EXACT [] synonym: "down-regulation of ion transport" EXACT [] synonym: "downregulation of ion transport" EXACT [] is_a: GO:0043269 ! regulation of monoatomic ion transport is_a: GO:0051051 ! negative regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006811 ! negatively regulates monoatomic ion transport relationship: RO:0002212 GO:0006811 ! negatively regulates monoatomic ion transport [Term] id: GO:0043279 name: response to alkaloid namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active." [GOC:jl] is_a: GO:0010243 ! response to organonitrogen compound intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:22315 ! has primary input alkaloid relationship: RO:0004009 CHEBI:22315 ! has primary input alkaloid [Term] id: GO:0043292 name: contractile fiber namespace: cellular_component def: "Fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle." [GOC:go_curators, ISBN:0815316194] synonym: "contractile fibre" EXACT [] is_a: GO:0043232 ! intracellular non-membrane-bounded organelle is_a: GO:0099512 ! supramolecular fiber is_a: UBERON:0004120 ! mesoderm-derived structure relationship: BFO:0000050 CL:0000187 ! part of muscle cell relationship: BFO:0000050 GO:0005737 ! part of cytoplasm [Term] id: GO:0043353 name: enucleate erythrocyte differentiation namespace: biological_process def: "The process in which a myeloid precursor cell acquires specialized features of an erythrocyte without a nucleus. An example of this process is found in Mus musculus." [GOC:go_curators] synonym: "enucleate RBC differentiation" EXACT [CL:0000232] synonym: "enucleate red blood cell differentiation" EXACT [CL:0000232] is_a: GO:0030218 ! erythrocyte differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000595 ! results in acquisition of features of enucleate erythrocyte relationship: RO:0002315 CL:0000595 ! results in acquisition of features of enucleate erythrocyte [Term] id: GO:0043354 name: enucleate erythrocyte maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for an enucleate erythrocyte to attain its fully functional state. An enucleate erythrocyte is an erythrocyte without a nucleus." [GOC:go_curators] synonym: "enucleate RBC maturation" EXACT [CL:0000232] synonym: "enucleate red blood cell maturation" EXACT [CL:0000232] is_a: GO:0043249 ! erythrocyte maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 CL:0000595 ! results in maturation of enucleate erythrocyte relationship: BFO:0000050 GO:0048822 ! part of enucleate erythrocyte development relationship: RO:0002299 CL:0000595 ! results in maturation of enucleate erythrocyte [Term] id: GO:0043362 name: nucleate erythrocyte maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for a nucleate erythrocyte to attain its fully functional state. A nucleate erythrocyte is an erythrocyte with a nucleus." [GOC:devbiol, GOC:jl] synonym: "nucleate RBC maturation" EXACT [CL:0000232] synonym: "nucleate red blood cell maturation" EXACT [CL:0000232] is_a: GO:0043249 ! erythrocyte maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 CL:0000562 ! results in maturation of nucleate erythrocyte relationship: BFO:0000050 GO:0048823 ! part of nucleate erythrocyte development relationship: RO:0002299 CL:0000562 ! results in maturation of nucleate erythrocyte [Term] id: GO:0043363 name: nucleate erythrocyte differentiation namespace: biological_process def: "The process in which a myeloid precursor cell acquires specializes features of an erythrocyte with a nucleus, as found in non-mammalian vertebrates such as birds." [GOC:jl] synonym: "nucleate RBC differentiation" EXACT [CL:0000232] synonym: "nucleate red blood cell differentiation" EXACT [CL:0000232] is_a: GO:0030218 ! erythrocyte differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000562 ! results in acquisition of features of nucleate erythrocyte relationship: RO:0002315 CL:0000562 ! results in acquisition of features of nucleate erythrocyte [Term] id: GO:0043434 name: response to peptide hormone namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals." [PMID:11027914, PMID:15134857, Wikipedia:Peptide_hormone] synonym: "response to peptide hormone stimulus" EXACT [GOC:dos] synonym: "response to polypeptide hormone stimulus" EXACT [] is_a: GO:0009725 ! response to hormone is_a: GO:1901652 ! response to peptide intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:25905 ! has primary input peptide hormone relationship: RO:0004009 CHEBI:25905 ! has primary input peptide hormone [Term] id: GO:0043436 name: oxoacid metabolic process namespace: biological_process def: "The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons)." [Wikipedia:Oxyacid] synonym: "keto acid metabolic process" EXACT [] synonym: "keto acid metabolism" EXACT [] synonym: "ketoacid metabolic process" EXACT [] synonym: "ketoacid metabolism" EXACT [] synonym: "oxo acid metabolic process" EXACT [] synonym: "oxo acid metabolism" EXACT [] synonym: "oxoacid metabolism" EXACT [] is_a: GO:0006082 ! organic acid metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:35406 ! has primary input or output oxoanion relationship: RO:0004007 CHEBI:35406 ! has primary input or output oxoanion [Term] id: GO:0043455 name: regulation of secondary metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of secondary metabolism, the chemical reactions and pathways involving compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon." [GOC:jl] synonym: "regulation of secondary metabolism" EXACT [] is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0019748 ! regulates (processual) secondary metabolic process relationship: RO:0002211 GO:0019748 ! regulates (processual) secondary metabolic process [Term] id: GO:0043467 name: regulation of generation of precursor metabolites and energy namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and the processes involved in the liberation of energy from these substances." [GOC:jl] is_a: GO:0031323 ! regulation of cellular metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006091 ! regulates (processual) generation of precursor metabolites and energy relationship: RO:0002211 GO:0006091 ! regulates (processual) generation of precursor metabolites and energy [Term] id: GO:0043470 name: regulation of carbohydrate catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates." [GOC:mlg] is_a: GO:0006109 ! regulation of carbohydrate metabolic process is_a: GO:0009894 ! regulation of catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0016052 ! regulates (processual) carbohydrate catabolic process relationship: RO:0002211 GO:0016052 ! regulates (processual) carbohydrate catabolic process [Term] id: GO:0043473 name: pigmentation namespace: biological_process def: "The accumulation of pigment in an organism, tissue or cell, either by increased deposition or by increased number of cells." [GOC:jl] is_a: GO:0008150 ! biological_process relationship: RO:0002160 NCBITaxon:131567 ! only in taxon cellular organisms relationship: RO:0002162 NCBITaxon:131567 {all_only="true"} ! in taxon cellular organisms [Term] id: GO:0043500 name: muscle adaptation namespace: biological_process def: "A process in which muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities." [GOC:mtg_muscle, PMID:11181628, PMID:11449884, PMID:12605307] is_a: GO:0003012 ! muscle system process is_a: GO:0050896 ! response to stimulus relationship: BFO:0000066 UBERON:0002385 ! occurs in muscle tissue [Term] id: GO:0043501 name: skeletal muscle adaptation namespace: biological_process def: "Any process in which skeletal muscles change their phenotypic profiles in response to altered functional demands and a variety of signals." [GOC:mtg_muscle, PMID:11181628, PMID:11449884, PMID:12605307] is_a: GO:0014888 ! striated muscle adaptation intersection_of: GO:0043500 ! muscle adaptation intersection_of: BFO:0000066 UBERON:0001134 ! occurs in skeletal muscle tissue relationship: BFO:0000066 UBERON:0001134 ! occurs in skeletal muscle tissue [Term] id: GO:0043502 name: regulation of muscle adaptation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of muscle adaptation." [GOC:go_curators, GOC:mtg_muscle] is_a: GO:0048583 ! regulation of response to stimulus is_a: GO:0090257 ! regulation of muscle system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0043500 ! regulates (processual) muscle adaptation relationship: RO:0002211 GO:0043500 ! regulates (processual) muscle adaptation [Term] id: GO:0043523 name: regulation of neuron apoptotic process namespace: biological_process def: "Any process that modulates the occurrence or rate of cell death by apoptotic process in neurons." [GOC:go_curators, GOC:mtg_apoptosis] synonym: "regulation of apoptosis of neuronal cells" EXACT [] synonym: "regulation of apoptosis of neurons" EXACT [] synonym: "regulation of neuron programmed cell death" EXACT [] synonym: "regulation of neuronal cell programmed cell death" EXACT [] synonym: "regulation of programmed cell death of neuronal cells" EXACT [] synonym: "regulation of programmed cell death, neurons" EXACT [] is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0051402 ! regulates (processual) neuron apoptotic process relationship: RO:0002211 GO:0051402 ! regulates (processual) neuron apoptotic process [Term] id: GO:0043524 name: negative regulation of neuron apoptotic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons." [GOC:go_curators, GOC:mtg_apoptosis] synonym: "down regulation of neuron apoptosis" EXACT [] synonym: "down-regulation of neuron apoptosis" EXACT [] synonym: "downregulation of neuron apoptosis" EXACT [] synonym: "negative regulation of programmed cell death, neurons" EXACT [] is_a: GO:0043066 ! negative regulation of apoptotic process is_a: GO:0043523 ! regulation of neuron apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0051402 ! negatively regulates neuron apoptotic process relationship: RO:0002212 GO:0051402 ! negatively regulates neuron apoptotic process [Term] id: GO:0043525 name: positive regulation of neuron apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process." [GOC:go_curators, GOC:mtg_apoptosis] synonym: "positive regulation of programmed cell death, neurons" EXACT [] synonym: "up regulation of neuron apoptosis" EXACT [] synonym: "up-regulation of neuron apoptosis" EXACT [] synonym: "upregulation of neuron apoptosis" EXACT [] is_a: GO:0043065 ! positive regulation of apoptotic process is_a: GO:0043523 ! regulation of neuron apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0051402 ! positively regulates neuron apoptotic process relationship: RO:0002213 GO:0051402 ! positively regulates neuron apoptotic process [Term] id: GO:0043534 name: blood vessel endothelial cell migration namespace: biological_process def: "The orderly movement of an endothelial cell into the extracellular matrix in order to form new blood vessels during angiogenesis." [PMID:11166264] is_a: GO:0043542 ! endothelial cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000071 ! results in movement of blood vessel endothelial cell relationship: RO:0002565 CL:0000071 ! results in movement of blood vessel endothelial cell [Term] id: GO:0043535 name: regulation of blood vessel endothelial cell migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the migration of the endothelial cells of blood vessels." [GOC:go_curators] is_a: GO:0010594 ! regulation of endothelial cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0043534 ! regulates (processual) blood vessel endothelial cell migration relationship: RO:0002211 GO:0043534 ! regulates (processual) blood vessel endothelial cell migration [Term] id: GO:0043536 name: positive regulation of blood vessel endothelial cell migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels." [GOC:go_curators] synonym: "up regulation of blood vessel endothelial cell migration" EXACT [] synonym: "up-regulation of blood vessel endothelial cell migration" EXACT [] synonym: "upregulation of blood vessel endothelial cell migration" EXACT [] is_a: GO:0010595 ! positive regulation of endothelial cell migration is_a: GO:0043535 ! regulation of blood vessel endothelial cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0043534 ! positively regulates blood vessel endothelial cell migration relationship: RO:0002213 GO:0043534 ! positively regulates blood vessel endothelial cell migration [Term] id: GO:0043537 name: negative regulation of blood vessel endothelial cell migration namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the migration of the endothelial cells of blood vessels." [GOC:go_curators] synonym: "down regulation of blood vessel endothelial cell migration" EXACT [] synonym: "down-regulation of blood vessel endothelial cell migration" EXACT [] synonym: "downregulation of blood vessel endothelial cell migration" EXACT [] is_a: GO:0010596 ! negative regulation of endothelial cell migration is_a: GO:0043535 ! regulation of blood vessel endothelial cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0043534 ! negatively regulates blood vessel endothelial cell migration relationship: RO:0002212 GO:0043534 ! negatively regulates blood vessel endothelial cell migration [Term] id: GO:0043542 name: endothelial cell migration namespace: biological_process def: "The orderly movement of an endothelial cell into the extracellular matrix to form an endothelium." [GOC:go_curators] is_a: GO:0010631 ! epithelial cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000115 ! results in movement of endothelial cell relationship: RO:0002565 CL:0000115 ! results in movement of endothelial cell [Term] id: GO:0043549 name: regulation of kinase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." [GOC:bf] is_a: GO:0042325 ! regulation of phosphorylation is_a: GO:0051338 ! regulation of transferase activity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0016301 ! regulates (processual) kinase activity relationship: RO:0002211 GO:0016301 ! regulates (processual) kinase activity [Term] id: GO:0043576 name: regulation of respiratory gaseous exchange namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the process of gaseous exchange between an organism and its environment." [GOC:jl] is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007585 ! regulates (processual) respiratory gaseous exchange by respiratory system relationship: RO:0002211 GO:0007585 ! regulates (processual) respiratory gaseous exchange by respiratory system [Term] id: GO:0043588 name: skin development namespace: biological_process def: "The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue." [GOC:jl, UBERON:0002097] synonym: "animal skin development" EXACT [] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002097 ! results in development of skin of body relationship: RO:0002296 UBERON:0002097 ! results in development of skin of body [Term] id: GO:0043589 name: skin morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the skin are generated and organized. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner, sensitive and vascular dermis (cutis, corium or true skin) composed mostly of connective tissue." [GOC:jl, UBERON:0002097] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002097 ! results in morphogenesis of skin of body relationship: BFO:0000050 GO:0043588 ! part of skin development relationship: RO:0002298 UBERON:0002097 ! results in morphogenesis of skin of body [Term] id: GO:0043603 name: amide metabolic process namespace: biological_process def: "The chemical reactions and pathways involving an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group, as carried out by individual cells." [GOC:curators] synonym: "amide metabolism" EXACT [] synonym: "cellular amide metabolic process" EXACT [] is_a: GO:0006807 ! nitrogen compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:32988 ! has primary input or output amide relationship: RO:0004007 CHEBI:32988 ! has primary input or output amide [Term] id: GO:0043604 name: amide biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group." [GOC:curators] is_a: GO:0043603 ! amide metabolic process is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:32988 ! has primary output amide relationship: RO:0004008 CHEBI:32988 ! has primary output amide [Term] id: GO:0043605 name: amide catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group." [GOC:curators] synonym: "cellular amide catabolic process" EXACT [] is_a: GO:0009056 ! catabolic process is_a: GO:0043603 ! amide metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004008 CHEBI:32988 ! has primary output amide relationship: RO:0004008 CHEBI:32988 ! has primary output amide [Term] id: GO:0043648 name: dicarboxylic acid metabolic process namespace: biological_process def: "The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing two carboxyl (COOH) groups or anions (COO-)." [ISBN:0198506732] synonym: "dicarboxylate metabolic process" EXACT [] synonym: "dicarboxylate metabolism" EXACT [] synonym: "dicarboxylic acid metabolism" EXACT [] is_a: GO:0019752 ! carboxylic acid metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:35693 ! has primary input or output dicarboxylic acid anion relationship: RO:0004007 CHEBI:35693 ! has primary input or output dicarboxylic acid anion [Term] id: GO:0043649 name: dicarboxylic acid catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups." [ISBN:0198506732] synonym: "dicarboxylate catabolic process" EXACT [] synonym: "dicarboxylate catabolism" EXACT [] synonym: "dicarboxylic acid breakdown" EXACT [] synonym: "dicarboxylic acid catabolism" EXACT [] synonym: "dicarboxylic acid degradation" EXACT [] is_a: GO:0043648 ! dicarboxylic acid metabolic process is_a: GO:0046395 ! carboxylic acid catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:35693 ! has primary input dicarboxylic acid anion relationship: RO:0004009 CHEBI:35693 ! has primary input dicarboxylic acid anion [Term] id: GO:0043650 name: dicarboxylic acid biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups." [ISBN:0198506732] synonym: "dicarboxylate biosynthesis" EXACT [] synonym: "dicarboxylate biosynthetic process" EXACT [] synonym: "dicarboxylic acid anabolism" EXACT [] synonym: "dicarboxylic acid biosynthesis" EXACT [] synonym: "dicarboxylic acid formation" EXACT [] synonym: "dicarboxylic acid synthesis" EXACT [] is_a: GO:0043648 ! dicarboxylic acid metabolic process is_a: GO:0046394 ! carboxylic acid biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:35693 ! has primary output dicarboxylic acid anion relationship: RO:0004008 CHEBI:35693 ! has primary output dicarboxylic acid anion [Term] id: GO:0043931 name: ossification involved in bone maturation namespace: biological_process def: "The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in the progression of the skeleton from its formation to its mature state." [GOC:dph, GOC:mah, GOC:mtg_mpo] synonym: "ossification involved in skeletal development" EXACT [GOC:dph] is_a: GO:0001503 ! ossification intersection_of: GO:0001503 ! ossification intersection_of: BFO:0000050 GO:0070977 ! part of bone maturation relationship: BFO:0000050 GO:0070977 ! part of bone maturation [Term] id: GO:0043933 name: protein-containing complex organization namespace: biological_process def: "Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex." [GOC:mah] synonym: "protein complex subunit organisation" EXACT [GOC:mah] synonym: "protein complex subunit organization" EXACT [] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0032991 ! results in organization of protein-containing complex relationship: RO:0002592 GO:0032991 ! results in organization of protein-containing complex creation_date: 2010-09-08T10:01:42Z [Term] id: GO:0044042 name: glucan metabolic process namespace: biological_process def: "The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues." [GOC:jl] synonym: "glucan metabolism" EXACT [] is_a: GO:0005976 ! polysaccharide metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:37163 ! has primary input or output glucan relationship: RO:0004007 CHEBI:37163 ! has primary input or output glucan [Term] id: GO:0044057 name: regulation of system process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system." [GOC:jl] is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003008 ! regulates (processual) system process relationship: RO:0002211 GO:0003008 ! regulates (processual) system process [Term] id: GO:0044058 name: regulation of digestive system process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." [GOC:jl] is_a: GO:0044057 ! regulation of system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0022600 ! regulates (processual) digestive system process relationship: RO:0002211 GO:0022600 ! regulates (processual) digestive system process [Term] id: GO:0044060 name: regulation of endocrine process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of an endocrine process, a process involving the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system." [GOC:jl] synonym: "regulation of endocrine system process" EXACT [] is_a: GO:0044057 ! regulation of system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0050886 ! regulates (processual) endocrine process relationship: RO:0002211 GO:0050886 ! regulates (processual) endocrine process [Term] id: GO:0044062 name: regulation of excretion namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of excretion, the elimination by an organism of the waste products that arise as a result of metabolic activity." [GOC:jl] is_a: GO:0044057 ! regulation of system process is_a: GO:0051046 ! regulation of secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007588 ! regulates (processual) excretion relationship: RO:0002211 GO:0007588 ! regulates (processual) excretion [Term] id: GO:0044065 name: regulation of respiratory system process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a respiratory system process, an organ system process carried out by any of the organs or tissues of the respiratory system." [GOC:jl] is_a: GO:0043576 ! regulation of respiratory gaseous exchange is_a: GO:0044057 ! regulation of system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003016 ! regulates (processual) respiratory system process relationship: RO:0002211 GO:0003016 ! regulates (processual) respiratory system process [Term] id: GO:0044085 name: cellular component biogenesis namespace: biological_process def: "A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component." [GOC:jl, GOC:mah] synonym: "cellular component biogenesis at cellular level" EXACT [] is_a: GO:0071840 ! cellular component organization or biogenesis [Term] id: GO:0044087 name: regulation of cellular component biogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component." [GOC:jl] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0044085 ! regulates (processual) cellular component biogenesis relationship: RO:0002211 GO:0044085 ! regulates (processual) cellular component biogenesis [Term] id: GO:0044088 name: regulation of vacuole organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole." [GOC:jl, GOC:mah] synonym: "regulation of vacuole organisation" EXACT [GOC:mah] is_a: GO:0033043 ! regulation of organelle organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007033 ! regulates (processual) vacuole organization relationship: RO:0002211 GO:0007033 ! regulates (processual) vacuole organization [Term] id: GO:0044089 name: positive regulation of cellular component biogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component." [GOC:jl] is_a: GO:0044087 ! regulation of cellular component biogenesis is_a: GO:0048522 ! positive regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0044085 ! positively regulates cellular component biogenesis relationship: RO:0002213 GO:0044085 ! positively regulates cellular component biogenesis [Term] id: GO:0044090 name: positive regulation of vacuole organization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole." [GOC:jl, GOC:mah] synonym: "positive regulation of vacuole organisation" EXACT [GOC:mah] is_a: GO:0010638 ! positive regulation of organelle organization is_a: GO:0044088 ! regulation of vacuole organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007033 ! positively regulates vacuole organization relationship: RO:0002213 GO:0007033 ! positively regulates vacuole organization [Term] id: GO:0044091 name: membrane biogenesis namespace: biological_process def: "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a membrane." [GOC:jl] is_a: GO:0044085 ! cellular component biogenesis intersection_of: GO:0044085 ! cellular component biogenesis intersection_of: RO:0004008 GO:0016020 ! has primary output membrane relationship: RO:0004008 GO:0016020 ! has primary output membrane [Term] id: GO:0044092 name: negative regulation of molecular function namespace: biological_process def: "Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding." [GO:jl] is_a: GO:0065009 ! regulation of molecular function intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0003674 ! negatively regulates molecular_function relationship: RO:0002212 GO:0003674 ! negatively regulates molecular_function creation_date: 2009-04-21T04:07:27Z [Term] id: GO:0044093 name: positive regulation of molecular function namespace: biological_process def: "Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding." [GO:jl] is_a: GO:0065009 ! regulation of molecular function intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0003674 ! positively regulates molecular_function relationship: RO:0002213 GO:0003674 ! positively regulates molecular_function creation_date: 2009-04-21T04:11:06Z [Term] id: GO:0044207 name: translation initiation ternary complex namespace: cellular_component def: "A ribonucleoprotein complex that contains aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator)." [GOC:jl] synonym: "translation initiation (ternary) complex" EXACT [] is_a: GO:1990904 ! ribonucleoprotein complex relationship: BFO:0000050 GO:0005737 ! part of cytoplasm creation_date: 2009-10-22T02:38:55Z [Term] id: GO:0044237 name: cellular metabolic process namespace: biological_process def: "The chemical reactions and pathways by which individual cells transform chemical substances." [GOC:go_curators] synonym: "cellular metabolism" EXACT [] is_a: GO:0008152 ! metabolic process is_a: GO:0009987 ! cellular process [Term] id: GO:0044238 name: primary metabolic process namespace: biological_process namespace: protein def: "The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism." [GOC:go_curators] synonym: "primary metabolism" EXACT [] is_a: GO:0008152 ! metabolic process [Term] id: GO:0044248 name: cellular catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells." [GOC:jl] synonym: "cellular breakdown" EXACT [] synonym: "cellular catabolism" EXACT [] synonym: "cellular degradation" EXACT [] is_a: GO:0009056 ! catabolic process is_a: GO:0044237 ! cellular metabolic process [Term] id: GO:0044249 name: cellular biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." [GOC:jl] synonym: "cellular anabolism" EXACT [] synonym: "cellular biosynthesis" EXACT [] synonym: "cellular formation" EXACT [] synonym: "cellular synthesis" EXACT [] is_a: GO:0009058 ! biosynthetic process is_a: GO:0044237 ! cellular metabolic process [Term] id: GO:0044258 name: intestinal lipid catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown into fatty acids and monoglycerides of lipids in the small intestine. Lipids are broken down by lipases released by the pancreas." [GOC:jl, http://www.emc.maricopa.edu/] synonym: "intestinal lipid breakdown" EXACT [] synonym: "intestinal lipid catabolism" EXACT [] synonym: "intestinal lipid degradation" EXACT [] is_a: GO:0016042 ! lipid catabolic process intersection_of: GO:0016042 ! lipid catabolic process intersection_of: BFO:0000066 UBERON:0000160 ! occurs in intestine relationship: BFO:0000066 UBERON:0000160 ! occurs in intestine [Term] id: GO:0044270 name: cellular nitrogen compound catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of organic and inorganic nitrogenous compounds." [GOC:jl, ISBN:0198506732] is_a: GO:0034641 ! cellular nitrogen compound metabolic process is_a: GO:0044248 ! cellular catabolic process [Term] id: GO:0044271 name: cellular nitrogen compound biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of organic and inorganic nitrogenous compounds." [GOC:jl, ISBN:0198506732] is_a: GO:0034641 ! cellular nitrogen compound metabolic process is_a: GO:0044249 ! cellular biosynthetic process [Term] id: GO:0044272 name: sulfur compound biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione." [GOC:jl] synonym: "sulfur compound anabolism" EXACT [] synonym: "sulfur compound biosynthesis" EXACT [] synonym: "sulfur compound formation" EXACT [] synonym: "sulfur compound synthesis" EXACT [] is_a: GO:0006790 ! sulfur compound metabolic process is_a: GO:0044249 ! cellular biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:26835 ! has primary output sulfur molecular entity relationship: RO:0004008 CHEBI:26835 ! has primary output sulfur molecular entity [Term] id: GO:0044273 name: sulfur compound catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione." [GOC:jl] synonym: "sulfur compound breakdown" EXACT [] synonym: "sulfur compound catabolism" EXACT [] synonym: "sulfur compound degradation" EXACT [] is_a: GO:0006790 ! sulfur compound metabolic process is_a: GO:0044248 ! cellular catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:26835 ! has primary input sulfur molecular entity relationship: RO:0004009 CHEBI:26835 ! has primary input sulfur molecular entity [Term] id: GO:0044281 name: small molecule metabolic process namespace: biological_process def: "The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule." [GOC:curators, GOC:pde, GOC:vw] synonym: "small molecule metabolism" EXACT [] is_a: GO:0008152 ! metabolic process creation_date: 2010-01-26T12:05:20Z [Term] id: GO:0044282 name: small molecule catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of small molecules, any low molecular weight, monomeric, non-encoded molecule." [GOC:curators, GOC:vw] synonym: "small molecule catabolism" EXACT [] is_a: GO:0009056 ! catabolic process is_a: GO:0044281 ! small molecule metabolic process creation_date: 2010-01-26T12:06:10Z [Term] id: GO:0044283 name: small molecule biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of small molecules, any low molecular weight, monomeric, non-encoded molecule." [GOC:curators, GOC:pde, GOC:vw] synonym: "small molecule biosynthesis" EXACT [] is_a: GO:0009058 ! biosynthetic process is_a: GO:0044281 ! small molecule metabolic process creation_date: 2010-01-26T12:06:49Z [Term] id: GO:0044297 name: cell body namespace: cellular_component def: "The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections." [GOC:go_curators] synonym: "cell soma" EXACT [] xref: FBbt:00005107 xref: FMA:67301 xref: Wikipedia:Cell_body is_a: GO:0110165 ! cellular anatomical entity relationship: BFO:0000050 CL:0000000 ! part of cell creation_date: 2010-02-05T10:37:16Z [Term] id: GO:0044342 name: type B pancreatic cell proliferation namespace: biological_process def: "The multiplication or reproduction of pancreatic B cells, resulting in the expansion of an pancreatic B cell population. Pancreatic B cell are cells of the pancreas that secrete insulin." [GOC:jl, GOC:yaf] synonym: "pancreatic B cell proliferation" EXACT [GOC:mah] synonym: "pancreatic beta cell proliferation" EXACT [] is_a: GO:0050673 ! epithelial cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000169 ! acts on population of type B pancreatic cell relationship: RO:0012003 CL:0000169 ! acts on population of type B pancreatic cell creation_date: 2010-08-25T01:44:51Z [Term] id: GO:0044346 name: fibroblast apoptotic process namespace: biological_process def: "Any apoptotic process in a fibroblast, a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules." [CL:0000057, GOC:jl, GOC:mtg_apoptosis, GOC:yaf] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000057 ! occurs in fibroblast relationship: BFO:0000066 CL:0000057 ! occurs in fibroblast creation_date: 2010-09-23T11:33:38Z [Term] id: GO:0044380 name: protein localization to cytoskeleton namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within the cytoskeleton." [GOC:jl] synonym: "protein localisation to cytoskeleton" EXACT [GOC:mah] is_a: GO:0033365 ! protein localization to organelle intersection_of: GO:0008104 ! protein localization intersection_of: RO:0002339 GO:0005856 ! has target end location cytoskeleton relationship: RO:0002339 GO:0005856 ! has target end location cytoskeleton creation_date: 2011-12-13T11:43:24Z [Term] id: GO:0044419 name: biological process involved in interspecies interaction between organisms namespace: biological_process def: "Any process evolved to enable an interaction with an organism of a different species." [GOC:cc] synonym: "interaction with another species" EXACT [] synonym: "interspecies interaction" EXACT [] synonym: "interspecies interaction between organisms" EXACT [] synonym: "interspecies interaction with other organisms" EXACT [] is_a: GO:0008150 ! biological_process [Term] id: GO:0044458 name: motile cilium assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form a motile cilium." [GO_REF:0000079, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:19776033, PMID:21129373, ZFIN:dsf] is_a: GO:0060271 ! cilium assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0031514 ! results in assembly of motile cilium relationship: RO:0002588 GO:0031514 ! results in assembly of motile cilium creation_date: 2015-02-06T17:23:23Z [Term] id: GO:0044550 name: secondary metabolite biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon." [GOC:jl] synonym: "secondary metabolite biosynthesis" EXACT [] is_a: GO:0009058 ! biosynthetic process is_a: GO:0019748 ! secondary metabolic process creation_date: 2012-03-29T01:55:18Z [Term] id: GO:0044565 name: dendritic cell proliferation namespace: biological_process def: "The expansion of a dendritic cell population by cell division. A dendritic cell is a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation." [CL:0000451, PMID:18469816] is_a: GO:0032943 ! mononuclear cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000451 ! acts on population of dendritic cell relationship: RO:0012003 CL:0000451 ! acts on population of dendritic cell creation_date: 2012-04-05T04:31:39Z [Term] id: GO:0044566 name: chondrocyte activation namespace: biological_process def: "A change in the morphology or behavior of a chondrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. A chondrocyte is a polymorphic cell that forms cartilage." [CL:0000138, GOC:jl] is_a: GO:0001775 ! cell activation intersection_of: GO:0001775 ! cell activation intersection_of: RO:0004009 CL:0000138 ! has primary input chondrocyte relationship: RO:0004009 CL:0000138 ! has primary input chondrocyte creation_date: 2012-04-05T04:45:38Z [Term] id: GO:0044703 name: multi-organism reproductive process namespace: biological_process def: "A biological process that directly contributes to the process of producing new individuals, involving another organism." [GOC:jl] is_a: GO:0022414 ! reproductive process creation_date: 2012-09-19T15:56:30Z [Term] id: GO:0044706 name: multi-multicellular organism process namespace: biological_process def: "A multicellular organism process which involves another multicellular organism of the same or different species." [GOC:jl] is_a: GO:0032501 ! multicellular organismal process creation_date: 2012-09-19T16:06:16Z [Term] id: GO:0044782 name: cilium organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole." [GOC:cilia, GOC:jl] synonym: "microtubule-based flagellum organization" EXACT [] is_a: GO:0006996 ! organelle organization is_a: GO:0120036 ! plasma membrane bounded cell projection organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0005929 ! results in organization of cilium relationship: RO:0002160 NCBITaxon:2759 ! only in taxon Eukaryota relationship: RO:0002162 NCBITaxon:2759 {all_only="true"} ! in taxon Eukaryota relationship: RO:0002592 GO:0005929 ! results in organization of cilium creation_date: 2013-03-27T15:09:58Z [Term] id: GO:0045026 name: plasma membrane fusion namespace: biological_process def: "The joining of the lipid bilayer membrane that surround a cell with that of another cell, producing a single cell." [GOC:elh, GOC:mtg_muscle] is_a: GO:0007009 ! plasma membrane organization is_a: GO:0061025 ! membrane fusion intersection_of: GO:0009987 ! cellular process intersection_of: RO:0012008 GO:0005886 ! results in fusion of plasma membrane relationship: RO:0012008 GO:0005886 ! results in fusion of plasma membrane [Term] id: GO:0045120 name: pronucleus namespace: cellular_component def: "The nucleus of either the ovum or the spermatozoon following fertilization. Thus, in the fertilized ovum, there are two pronuclei, one originating from the ovum, the other from the spermatozoon that brought about fertilization; they approach each other, but do not fuse until just before the first cleavage, when each pronucleus loses its membrane to release its contents." [ISBN:0198506732] xref: Wikipedia:Pronucleus is_a: GO:0005634 ! nucleus relationship: RO:0002160 NCBITaxon:33208 ! only in taxon Metazoa relationship: RO:0002162 NCBITaxon:33208 {all_only="true"} ! in taxon Metazoa [Term] id: GO:0045132 name: meiotic chromosome segregation namespace: biological_process def: "The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets during M phase of the meiotic cell cycle." [GOC:ai, GOC:mah] is_a: GO:0098813 ! nuclear chromosome segregation is_a: GO:1903046 ! meiotic cell cycle process intersection_of: GO:0098813 ! nuclear chromosome segregation intersection_of: BFO:0000050 GO:0140013 ! part of meiotic nuclear division relationship: BFO:0000050 GO:0140013 ! part of meiotic nuclear division [Term] id: GO:0045137 name: development of primary sexual characteristics namespace: biological_process def: "The process whose specific outcome is the progression of the primary sexual characteristics over time, from their formation to the mature structures. The primary sexual characteristics are the testes in males and the ovaries in females and they develop in response to sex hormone secretion." [GOC:ai] is_a: GO:0003006 ! developmental process involved in reproduction relationship: BFO:0000050 GO:0007275 ! part of multicellular organism development relationship: BFO:0000050 GO:0007548 ! part of sex differentiation [Term] id: GO:0045144 name: meiotic sister chromatid segregation namespace: biological_process def: "The cell cycle process in which sister chromatids are organized and then physically separated and randomly apportioned to two sets during the second division of the meiotic cell cycle." [GOC:ai, ISBN:0815316194] synonym: "meiosis II, chromosome segregation" EXACT [] is_a: GO:0000819 ! sister chromatid segregation is_a: GO:0045132 ! meiotic chromosome segregation is_a: GO:0070192 ! chromosome organization involved in meiotic cell cycle intersection_of: GO:0000819 ! sister chromatid segregation intersection_of: BFO:0000050 GO:0007135 ! part of meiosis II relationship: BFO:0000050 GO:0007135 ! part of meiosis II [Term] id: GO:0045165 name: cell fate commitment namespace: biological_process def: "The cellular developmental process by which a cell establishes the intrinsic character of a cell or tissue region irreversibly committing it to a particular fate." [ISBN:0716731185] is_a: GO:0048869 ! cellular developmental process relationship: BFO:0000050 GO:0030154 ! part of cell differentiation [Term] id: GO:0045168 name: cell-cell signaling involved in cell fate commitment namespace: biological_process def: "Signaling at long or short range between cells that results in the commitment of a cell to a certain fate." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "cell fate commitment, cell-cell signaling" EXACT [] synonym: "cell fate commitment, cell-cell signalling" EXACT [] synonym: "cell-cell signaling during in cell fate commitment" EXACT [] synonym: "cell-cell signaling resulting in cell fate commitment" EXACT [] synonym: "cell-cell signalling during cell fate commitment" EXACT [] synonym: "cell-cell signalling resulting in cell fate commitment" EXACT [] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: BFO:0000050 GO:0045165 ! part of cell fate commitment relationship: BFO:0000050 GO:0045165 ! part of cell fate commitment [Term] id: GO:0045184 name: establishment of protein localization namespace: biological_process def: "The directed movement of a protein to a specific location." [GOC:bf] synonym: "establishment of protein localisation" EXACT [GOC:mah] synonym: "protein positioning" EXACT [] synonym: "protein recruitment" EXACT [] is_a: GO:0051234 ! establishment of localization intersection_of: GO:0051234 ! establishment of localization intersection_of: RO:0004009 CHEBI:36080 ! has primary input protein relationship: RO:0004009 CHEBI:36080 ! has primary input protein [Term] id: GO:0045196 name: establishment or maintenance of neuroblast polarity namespace: biological_process def: "Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system." [GOC:bf, GOC:mah, GOC:mtg_sensu, PMID:19375318, PMID:20066083] synonym: "establishment and/or maintenance of neuroblast cell polarity" EXACT [] is_a: GO:0007163 ! establishment or maintenance of cell polarity relationship: BFO:0000050 GO:0055059 ! part of asymmetric neuroblast division [Term] id: GO:0045200 name: establishment of neuroblast polarity namespace: biological_process def: "The specification and formation of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system." [GOC:bf, GOC:mtg_sensu] synonym: "establishment of neuroblast cell polarity" EXACT [] is_a: GO:0030010 ! establishment of cell polarity is_a: GO:0045196 ! establishment or maintenance of neuroblast polarity intersection_of: GO:0030010 ! establishment of cell polarity intersection_of: BFO:0000066 CL:0000031 ! occurs in neuroblast (sensu Vertebrata) relationship: BFO:0000066 CL:0000031 ! occurs in neuroblast (sensu Vertebrata) [Term] id: GO:0045202 name: synapse namespace: cellular_component def: "The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane." [GOC:aruk, ISBN:0198506732, PMID:24619342, PMID:29383328, PMID:31998110] synonym: "synaptic junction" EXACT [] xref: NIF_Subcellular:sao914572699 xref: Wikipedia:Chemical_synapse is_a: GO:0030054 ! cell junction relationship: RO:0002160 NCBITaxon:33208 ! only in taxon Metazoa relationship: RO:0002162 NCBITaxon:33208 {all_only="true"} ! in taxon Metazoa [Term] id: GO:0045214 name: sarcomere organization namespace: biological_process def: "The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." [GOC:bf] synonym: "sarcomere alignment" EXACT [] synonym: "sarcomere organisation" EXACT [] is_a: GO:0031032 ! actomyosin structure organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0030017 ! results in organization of sarcomere relationship: BFO:0000050 GO:0030239 ! part of myofibril assembly relationship: RO:0002592 GO:0030017 ! results in organization of sarcomere [Term] id: GO:0045216 name: cell-cell junction organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-cell junction. A cell-cell junction is a specialized region of connection between two cells." [GOC:ai, GOC:dph, GOC:jl, GOC:mah] synonym: "cell-cell junction assembly and maintenance" EXACT [] synonym: "cell-cell junction organisation" EXACT [GOC:mah] synonym: "intercellular junction assembly and maintenance" EXACT [] is_a: GO:0034330 ! cell junction organization intersection_of: GO:0034330 ! cell junction organization intersection_of: RO:0002592 GO:0005911 ! results in organization of cell-cell junction relationship: RO:0002592 GO:0005911 ! results in organization of cell-cell junction [Term] id: GO:0045222 name: CD4 biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of CD4, a CD marker that occurs on T-helper cells and is involved in MHC class II restricted interactions." [GOC:go_curators, ISBN:0198506732] synonym: "CD4 anabolism" EXACT [] synonym: "CD4 biosynthesis" EXACT [] synonym: "CD4 formation" EXACT [] synonym: "CD4 synthesis" EXACT [] is_a: GO:0009101 ! glycoprotein biosynthetic process is_a: GO:0019538 ! protein metabolic process is_a: GO:1901566 ! organonitrogen compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 PR:000001004 ! has primary output CD4 molecule relationship: RO:0004008 PR:000001004 ! has primary output CD4 molecule [Term] id: GO:0045223 name: regulation of CD4 production namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4." [GOC:go_curators] synonym: "regulation of CD4 anabolism" EXACT [] synonym: "regulation of CD4 biosynthesis" EXACT [] synonym: "regulation of CD4 biosynthetic process" EXACT [] synonym: "regulation of CD4 formation" EXACT [] synonym: "regulation of CD4 synthesis" EXACT [] is_a: GO:0010559 ! regulation of glycoprotein biosynthetic process is_a: GO:0051246 ! regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0045222 ! regulates (processual) CD4 biosynthetic process relationship: RO:0002211 GO:0045222 ! regulates (processual) CD4 biosynthetic process [Term] id: GO:0045224 name: positive regulation of CD4 production namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4." [GOC:go_curators] synonym: "positive regulation of CD4 anabolism" EXACT [] synonym: "positive regulation of CD4 biosynthesis" EXACT [] synonym: "positive regulation of CD4 biosynthetic process" EXACT [] synonym: "positive regulation of CD4 formation" EXACT [] synonym: "positive regulation of CD4 synthesis" EXACT [] synonym: "up regulation of CD4 biosynthetic process" EXACT [] synonym: "up-regulation of CD4 biosynthetic process" EXACT [] synonym: "upregulation of CD4 biosynthetic process" EXACT [] is_a: GO:0010560 ! positive regulation of glycoprotein biosynthetic process is_a: GO:0045223 ! regulation of CD4 production is_a: GO:0051247 ! positive regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0045222 ! positively regulates CD4 biosynthetic process relationship: RO:0002213 GO:0045222 ! positively regulates CD4 biosynthetic process [Term] id: GO:0045225 name: negative regulation of CD4 production namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4." [GOC:go_curators] synonym: "down regulation of CD4 biosynthetic process" EXACT [] synonym: "down-regulation of CD4 biosynthetic process" EXACT [] synonym: "downregulation of CD4 biosynthetic process" EXACT [] synonym: "negative regulation of CD4 anabolism" EXACT [] synonym: "negative regulation of CD4 biosynthesis" EXACT [] synonym: "negative regulation of CD4 biosynthetic process" EXACT [] synonym: "negative regulation of CD4 formation" EXACT [] synonym: "negative regulation of CD4 synthesis" EXACT [] is_a: GO:0010561 ! negative regulation of glycoprotein biosynthetic process is_a: GO:0045223 ! regulation of CD4 production is_a: GO:0051248 ! negative regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0045222 ! negatively regulates CD4 biosynthetic process relationship: RO:0002212 GO:0045222 ! negatively regulates CD4 biosynthetic process [Term] id: GO:0045229 name: external encapsulating structure organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of external structures that lie outside the plasma membrane and surround the entire cell." [GOC:ai, GOC:dph, GOC:jl, GOC:mah] synonym: "external encapsulating structure organisation" EXACT [] synonym: "external encapsulating structure organization and biogenesis" EXACT [GOC:dph, GOC:jl, GOC:mah] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0030312 ! results in organization of external encapsulating structure relationship: RO:0002592 GO:0030312 ! results in organization of external encapsulating structure [Term] id: GO:0045321 name: leukocyte activation namespace: biological_process def: "A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor." [GOC:add] synonym: "immune cell activation" EXACT [] synonym: "leucocyte activation" EXACT [] xref: Wikipedia:Immunologic_activation is_a: GO:0001775 ! cell activation is_a: GO:0002376 ! immune system process intersection_of: GO:0001775 ! cell activation intersection_of: RO:0004009 CL:0000738 ! has primary input leukocyte relationship: RO:0002160 NCBITaxon:7742 ! only in taxon Vertebrata relationship: RO:0002162 NCBITaxon:7742 {all_only="true"} ! in taxon Vertebrata relationship: RO:0004009 CL:0000738 ! has primary input leukocyte [Term] id: GO:0045444 name: fat cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat." [CL:0000136, GOC:go_curators] synonym: "adipocyte cell differentiation" EXACT [] synonym: "adipocyte differentiation" EXACT [] synonym: "adipose cell differentiation" EXACT [] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000136 ! results in acquisition of features of adipocyte relationship: RO:0002315 CL:0000136 ! results in acquisition of features of adipocyte [Term] id: GO:0045445 name: myoblast differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers." [CL:0000056, GOC:go_curators, GOC:mtg_muscle] synonym: "myoblast cell differentiation" EXACT [] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000056 ! results in acquisition of features of myoblast relationship: BFO:0000050 GO:0061061 ! part of muscle structure development relationship: RO:0002315 CL:0000056 ! results in acquisition of features of myoblast [Term] id: GO:0045446 name: endothelial cell differentiation namespace: biological_process def: "The process in which a mesodermal, bone marrow or neural crest cell acquires specialized features of an endothelial cell, a thin flattened cell. A layer of such cells lines the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium." [CL:0000115, GOC:go_curators] is_a: GO:0030855 ! epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000115 ! results in acquisition of features of endothelial cell relationship: BFO:0000050 GO:0003158 ! part of endothelium development relationship: RO:0002315 CL:0000115 ! results in acquisition of features of endothelial cell [Term] id: GO:0045580 name: regulation of T cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of T cell differentiation." [GOC:go_curators] synonym: "regulation of T lymphocyte differentiation" EXACT [] synonym: "regulation of T-cell differentiation" EXACT [] synonym: "regulation of T-lymphocyte differentiation" EXACT [] is_a: GO:0045619 ! regulation of lymphocyte differentiation is_a: GO:0050863 ! regulation of T cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030217 ! regulates (processual) T cell differentiation relationship: RO:0002211 GO:0030217 ! regulates (processual) T cell differentiation [Term] id: GO:0045581 name: negative regulation of T cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation." [GOC:go_curators] synonym: "down regulation of T cell differentiation" EXACT [] synonym: "down-regulation of T cell differentiation" EXACT [] synonym: "downregulation of T cell differentiation" EXACT [] synonym: "negative regulation of T lymphocyte differentiation" EXACT [] synonym: "negative regulation of T-cell differentiation" EXACT [] synonym: "negative regulation of T-lymphocyte differentiation" EXACT [] is_a: GO:0045580 ! regulation of T cell differentiation is_a: GO:0045620 ! negative regulation of lymphocyte differentiation is_a: GO:0050868 ! negative regulation of T cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030217 ! negatively regulates T cell differentiation relationship: RO:0002212 GO:0030217 ! negatively regulates T cell differentiation [Term] id: GO:0045582 name: positive regulation of T cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of T cell differentiation." [GOC:go_curators] synonym: "positive regulation of T lymphocyte differentiation" EXACT [] synonym: "positive regulation of T-cell differentiation" EXACT [] synonym: "positive regulation of T-lymphocyte differentiation" EXACT [] synonym: "up regulation of T cell differentiation" EXACT [] synonym: "up-regulation of T cell differentiation" EXACT [] synonym: "upregulation of T cell differentiation" EXACT [] is_a: GO:0045580 ! regulation of T cell differentiation is_a: GO:0045621 ! positive regulation of lymphocyte differentiation is_a: GO:0050870 ! positive regulation of T cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030217 ! positively regulates T cell differentiation relationship: RO:0002213 GO:0030217 ! positively regulates T cell differentiation [Term] id: GO:0045595 name: regulation of cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features." [GOC:go_curators] is_a: GO:0050793 ! regulation of developmental process is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030154 ! regulates (processual) cell differentiation relationship: RO:0002211 GO:0030154 ! regulates (processual) cell differentiation [Term] id: GO:0045596 name: negative regulation of cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation." [GOC:go_curators] synonym: "down regulation of cell differentiation" EXACT [] synonym: "down-regulation of cell differentiation" EXACT [] synonym: "downregulation of cell differentiation" EXACT [] is_a: GO:0045595 ! regulation of cell differentiation is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:0051093 ! negative regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030154 ! negatively regulates cell differentiation relationship: RO:0002212 GO:0030154 ! negatively regulates cell differentiation [Term] id: GO:0045597 name: positive regulation of cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell differentiation." [GOC:go_curators] synonym: "up regulation of cell differentiation" EXACT [] synonym: "up-regulation of cell differentiation" EXACT [] synonym: "upregulation of cell differentiation" EXACT [] is_a: GO:0045595 ! regulation of cell differentiation is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:0051094 ! positive regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030154 ! positively regulates cell differentiation relationship: RO:0002213 GO:0030154 ! positively regulates cell differentiation [Term] id: GO:0045598 name: regulation of fat cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of adipocyte differentiation." [GOC:go_curators] synonym: "regulation of adipocyte cell differentiation" EXACT [] synonym: "regulation of adipocyte differentiation" EXACT [] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0045444 ! regulates (processual) fat cell differentiation relationship: RO:0002211 GO:0045444 ! regulates (processual) fat cell differentiation [Term] id: GO:0045599 name: negative regulation of fat cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of adipocyte differentiation." [GOC:go_curators] synonym: "down regulation of fat cell differentiation" EXACT [] synonym: "down-regulation of fat cell differentiation" EXACT [] synonym: "downregulation of fat cell differentiation" EXACT [] synonym: "negative regulation of adipocyte cell differentiation" EXACT [] synonym: "negative regulation of adipocyte differentiation" EXACT [] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0045598 ! regulation of fat cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0045444 ! negatively regulates fat cell differentiation relationship: RO:0002212 GO:0045444 ! negatively regulates fat cell differentiation [Term] id: GO:0045600 name: positive regulation of fat cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of adipocyte differentiation." [GOC:go_curators] synonym: "positive regulation of adipocyte cell differentiation" EXACT [] synonym: "positive regulation of adipocyte differentiation" EXACT [] synonym: "up regulation of fat cell differentiation" EXACT [] synonym: "up-regulation of fat cell differentiation" EXACT [] synonym: "upregulation of fat cell differentiation" EXACT [] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0045598 ! regulation of fat cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0045444 ! positively regulates fat cell differentiation relationship: RO:0002213 GO:0045444 ! positively regulates fat cell differentiation [Term] id: GO:0045601 name: regulation of endothelial cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of endothelial cell differentiation." [GOC:go_curators] is_a: GO:0030856 ! regulation of epithelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0045446 ! regulates (processual) endothelial cell differentiation relationship: RO:0002211 GO:0045446 ! regulates (processual) endothelial cell differentiation [Term] id: GO:0045602 name: negative regulation of endothelial cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of endothelial cell differentiation." [GOC:go_curators] synonym: "down regulation of endothelial cell differentiation" EXACT [] synonym: "down-regulation of endothelial cell differentiation" EXACT [] synonym: "downregulation of endothelial cell differentiation" EXACT [] is_a: GO:0030857 ! negative regulation of epithelial cell differentiation is_a: GO:0045601 ! regulation of endothelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0045446 ! negatively regulates endothelial cell differentiation relationship: RO:0002212 GO:0045446 ! negatively regulates endothelial cell differentiation [Term] id: GO:0045603 name: positive regulation of endothelial cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of endothelial cell differentiation." [GOC:go_curators] synonym: "up regulation of endothelial cell differentiation" EXACT [] synonym: "up-regulation of endothelial cell differentiation" EXACT [] synonym: "upregulation of endothelial cell differentiation" EXACT [] is_a: GO:0030858 ! positive regulation of epithelial cell differentiation is_a: GO:0045601 ! regulation of endothelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0045446 ! positively regulates endothelial cell differentiation relationship: RO:0002213 GO:0045446 ! positively regulates endothelial cell differentiation [Term] id: GO:0045604 name: regulation of epidermal cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of epidermal cell differentiation." [GOC:go_curators] is_a: GO:0030856 ! regulation of epithelial cell differentiation is_a: GO:0045682 ! regulation of epidermis development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0009913 ! regulates (processual) epidermal cell differentiation relationship: RO:0002211 GO:0009913 ! regulates (processual) epidermal cell differentiation [Term] id: GO:0045605 name: negative regulation of epidermal cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal cell differentiation." [GOC:go_curators] synonym: "down regulation of epidermal cell differentiation" EXACT [] synonym: "down-regulation of epidermal cell differentiation" EXACT [] synonym: "downregulation of epidermal cell differentiation" EXACT [] is_a: GO:0030857 ! negative regulation of epithelial cell differentiation is_a: GO:0045604 ! regulation of epidermal cell differentiation is_a: GO:0045683 ! negative regulation of epidermis development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0009913 ! negatively regulates epidermal cell differentiation relationship: RO:0002212 GO:0009913 ! negatively regulates epidermal cell differentiation [Term] id: GO:0045606 name: positive regulation of epidermal cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of epidermal cell differentiation." [GOC:go_curators] synonym: "up regulation of epidermal cell differentiation" EXACT [] synonym: "up-regulation of epidermal cell differentiation" EXACT [] synonym: "upregulation of epidermal cell differentiation" EXACT [] is_a: GO:0030858 ! positive regulation of epithelial cell differentiation is_a: GO:0045604 ! regulation of epidermal cell differentiation is_a: GO:0045684 ! positive regulation of epidermis development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0009913 ! positively regulates epidermal cell differentiation relationship: RO:0002213 GO:0009913 ! positively regulates epidermal cell differentiation [Term] id: GO:0045619 name: regulation of lymphocyte differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of lymphocyte differentiation." [GOC:go_curators] is_a: GO:0051249 ! regulation of lymphocyte activation is_a: GO:1902105 ! regulation of leukocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030098 ! regulates (processual) lymphocyte differentiation relationship: RO:0002211 GO:0030098 ! regulates (processual) lymphocyte differentiation [Term] id: GO:0045620 name: negative regulation of lymphocyte differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte differentiation." [GOC:go_curators] synonym: "down regulation of lymphocyte differentiation" EXACT [] synonym: "down-regulation of lymphocyte differentiation" EXACT [] synonym: "downregulation of lymphocyte differentiation" EXACT [] is_a: GO:0045619 ! regulation of lymphocyte differentiation is_a: GO:0051250 ! negative regulation of lymphocyte activation is_a: GO:1902106 ! negative regulation of leukocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030098 ! negatively regulates lymphocyte differentiation relationship: RO:0002212 GO:0030098 ! negatively regulates lymphocyte differentiation [Term] id: GO:0045621 name: positive regulation of lymphocyte differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of lymphocyte differentiation." [GOC:go_curators] synonym: "up regulation of lymphocyte differentiation" EXACT [] synonym: "up-regulation of lymphocyte differentiation" EXACT [] synonym: "upregulation of lymphocyte differentiation" EXACT [] is_a: GO:0045619 ! regulation of lymphocyte differentiation is_a: GO:0051251 ! positive regulation of lymphocyte activation is_a: GO:1902107 ! positive regulation of leukocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030098 ! positively regulates lymphocyte differentiation relationship: RO:0002213 GO:0030098 ! positively regulates lymphocyte differentiation [Term] id: GO:0045637 name: regulation of myeloid cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of myeloid cell differentiation." [GOC:go_curators] is_a: GO:1903706 ! regulation of hemopoiesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030099 ! regulates (processual) myeloid cell differentiation relationship: RO:0002211 GO:0030099 ! regulates (processual) myeloid cell differentiation [Term] id: GO:0045638 name: negative regulation of myeloid cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation." [GOC:go_curators] synonym: "down regulation of myeloid cell differentiation" EXACT [] synonym: "down-regulation of myeloid cell differentiation" EXACT [] synonym: "downregulation of myeloid cell differentiation" EXACT [] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0045637 ! regulation of myeloid cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030099 ! negatively regulates myeloid cell differentiation relationship: RO:0002212 GO:0030099 ! negatively regulates myeloid cell differentiation [Term] id: GO:0045639 name: positive regulation of myeloid cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of myeloid cell differentiation." [GOC:go_curators] synonym: "up regulation of myeloid cell differentiation" EXACT [] synonym: "up-regulation of myeloid cell differentiation" EXACT [] synonym: "upregulation of myeloid cell differentiation" EXACT [] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0045637 ! regulation of myeloid cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030099 ! positively regulates myeloid cell differentiation relationship: RO:0002213 GO:0030099 ! positively regulates myeloid cell differentiation [Term] id: GO:0045646 name: regulation of erythrocyte differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of erythrocyte differentiation." [GOC:go_curators] synonym: "regulation of RBC differentiation" EXACT [CL:0000232] synonym: "regulation of red blood cell differentiation" EXACT [CL:0000232] is_a: GO:0045637 ! regulation of myeloid cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030218 ! regulates (processual) erythrocyte differentiation relationship: RO:0002211 GO:0030218 ! regulates (processual) erythrocyte differentiation [Term] id: GO:0045647 name: negative regulation of erythrocyte differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of erythrocyte differentiation." [GOC:go_curators] synonym: "down regulation of erythrocyte differentiation" EXACT [] synonym: "down-regulation of erythrocyte differentiation" EXACT [] synonym: "downregulation of erythrocyte differentiation" EXACT [] synonym: "negative regulation of RBC differentiation" EXACT [CL:0000232] synonym: "negative regulation of red blood cell differentiation" EXACT [CL:0000232] is_a: GO:0045638 ! negative regulation of myeloid cell differentiation is_a: GO:0045646 ! regulation of erythrocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030218 ! negatively regulates erythrocyte differentiation relationship: RO:0002212 GO:0030218 ! negatively regulates erythrocyte differentiation [Term] id: GO:0045648 name: positive regulation of erythrocyte differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation." [GOC:go_curators] synonym: "positive regulation of RBC differentiation" EXACT [CL:0000232] synonym: "positive regulation of red blood cell differentiation" EXACT [CL:0000232] synonym: "up regulation of erythrocyte differentiation" EXACT [] synonym: "up-regulation of erythrocyte differentiation" EXACT [] synonym: "upregulation of erythrocyte differentiation" EXACT [] is_a: GO:0045639 ! positive regulation of myeloid cell differentiation is_a: GO:0045646 ! regulation of erythrocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030218 ! positively regulates erythrocyte differentiation relationship: RO:0002213 GO:0030218 ! positively regulates erythrocyte differentiation [Term] id: GO:0045652 name: regulation of megakaryocyte differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of megakaryocyte differentiation." [GOC:go_curators] is_a: GO:0045637 ! regulation of myeloid cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030219 ! regulates (processual) megakaryocyte differentiation relationship: RO:0002211 GO:0030219 ! regulates (processual) megakaryocyte differentiation [Term] id: GO:0045653 name: negative regulation of megakaryocyte differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of megakaryocyte differentiation." [GOC:go_curators] synonym: "down regulation of megakaryocyte differentiation" EXACT [] synonym: "down-regulation of megakaryocyte differentiation" EXACT [] synonym: "downregulation of megakaryocyte differentiation" EXACT [] is_a: GO:0045638 ! negative regulation of myeloid cell differentiation is_a: GO:0045652 ! regulation of megakaryocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030219 ! negatively regulates megakaryocyte differentiation relationship: RO:0002212 GO:0030219 ! negatively regulates megakaryocyte differentiation [Term] id: GO:0045654 name: positive regulation of megakaryocyte differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of megakaryocyte differentiation." [GOC:go_curators] synonym: "up regulation of megakaryocyte differentiation" EXACT [] synonym: "up-regulation of megakaryocyte differentiation" EXACT [] synonym: "upregulation of megakaryocyte differentiation" EXACT [] is_a: GO:0045639 ! positive regulation of myeloid cell differentiation is_a: GO:0045652 ! regulation of megakaryocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030219 ! positively regulates megakaryocyte differentiation relationship: RO:0002213 GO:0030219 ! positively regulates megakaryocyte differentiation [Term] id: GO:0045661 name: regulation of myoblast differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:go_curators, GOC:mtg_muscle] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0045445 ! regulates (processual) myoblast differentiation relationship: RO:0002211 GO:0045445 ! regulates (processual) myoblast differentiation [Term] id: GO:0045662 name: negative regulation of myoblast differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:go_curators, GOC:mtg_muscle] synonym: "down regulation of myoblast differentiation" EXACT [] synonym: "down-regulation of myoblast differentiation" EXACT [] synonym: "downregulation of myoblast differentiation" EXACT [] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0045661 ! regulation of myoblast differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0045445 ! negatively regulates myoblast differentiation relationship: RO:0002212 GO:0045445 ! negatively regulates myoblast differentiation [Term] id: GO:0045663 name: positive regulation of myoblast differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:go_curators, GOC:mtg_muscle] synonym: "up regulation of myoblast differentiation" EXACT [] synonym: "up-regulation of myoblast differentiation" EXACT [] synonym: "upregulation of myoblast differentiation" EXACT [] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0045661 ! regulation of myoblast differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0045445 ! positively regulates myoblast differentiation relationship: RO:0002213 GO:0045445 ! positively regulates myoblast differentiation [Term] id: GO:0045664 name: regulation of neuron differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of neuron differentiation." [GOC:go_curators] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030182 ! regulates (processual) neuron differentiation relationship: RO:0002160 NCBITaxon:33208 ! only in taxon Metazoa relationship: RO:0002162 NCBITaxon:33208 {all_only="true"} ! in taxon Metazoa relationship: RO:0002211 GO:0030182 ! regulates (processual) neuron differentiation [Term] id: GO:0045665 name: negative regulation of neuron differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation." [GOC:go_curators] synonym: "down regulation of neuron differentiation" EXACT [] synonym: "down-regulation of neuron differentiation" EXACT [] synonym: "downregulation of neuron differentiation" EXACT [] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0045664 ! regulation of neuron differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030182 ! negatively regulates neuron differentiation relationship: RO:0002212 GO:0030182 ! negatively regulates neuron differentiation [Term] id: GO:0045666 name: positive regulation of neuron differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of neuron differentiation." [GOC:go_curators] synonym: "up regulation of neuron differentiation" EXACT [] synonym: "up-regulation of neuron differentiation" EXACT [] synonym: "upregulation of neuron differentiation" EXACT [] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0045664 ! regulation of neuron differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030182 ! positively regulates neuron differentiation relationship: RO:0002213 GO:0030182 ! positively regulates neuron differentiation [Term] id: GO:0045682 name: regulation of epidermis development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of epidermis development." [GOC:go_curators] synonym: "regulation of epidermal development" EXACT [] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0008544 ! regulates (processual) epidermis development relationship: RO:0002211 GO:0008544 ! regulates (processual) epidermis development [Term] id: GO:0045683 name: negative regulation of epidermis development namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of epidermis development." [GOC:go_curators] synonym: "down regulation of epidermis development" EXACT [] synonym: "down-regulation of epidermis development" EXACT [] synonym: "downregulation of epidermis development" EXACT [] synonym: "negative regulation of epidermal development" EXACT [] is_a: GO:0045682 ! regulation of epidermis development is_a: GO:0051093 ! negative regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0008544 ! negatively regulates epidermis development relationship: RO:0002212 GO:0008544 ! negatively regulates epidermis development [Term] id: GO:0045684 name: positive regulation of epidermis development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of epidermis development." [GOC:go_curators] synonym: "positive regulation of epidermal development" EXACT [] synonym: "up regulation of epidermis development" EXACT [] synonym: "up-regulation of epidermis development" EXACT [] synonym: "upregulation of epidermis development" EXACT [] is_a: GO:0045682 ! regulation of epidermis development is_a: GO:0051094 ! positive regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0008544 ! positively regulates epidermis development relationship: RO:0002213 GO:0008544 ! positively regulates epidermis development [Term] id: GO:0045685 name: regulation of glial cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of glia cell differentiation." [GOC:go_curators] synonym: "regulation of glia cell differentiation" EXACT [] synonym: "regulation of neuroglia differentiation" EXACT [] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0010001 ! regulates (processual) glial cell differentiation relationship: RO:0002211 GO:0010001 ! regulates (processual) glial cell differentiation [Term] id: GO:0045686 name: negative regulation of glial cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of glia cell differentiation." [GOC:go_curators] synonym: "down regulation of glial cell differentiation" EXACT [] synonym: "down-regulation of glial cell differentiation" EXACT [] synonym: "downregulation of glial cell differentiation" EXACT [] synonym: "negative regulation of glia cell differentiation" EXACT [] synonym: "negative regulation of neuroglia differentiation" EXACT [] is_a: GO:0014014 ! negative regulation of gliogenesis is_a: GO:0045685 ! regulation of glial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0010001 ! negatively regulates glial cell differentiation relationship: RO:0002212 GO:0010001 ! negatively regulates glial cell differentiation [Term] id: GO:0045687 name: positive regulation of glial cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of glia cell differentiation." [GOC:go_curators] synonym: "positive regulation of glia cell differentiation" EXACT [] synonym: "positive regulation of neuroglia differentiation" EXACT [] synonym: "up regulation of glial cell differentiation" EXACT [] synonym: "up-regulation of glial cell differentiation" EXACT [] synonym: "upregulation of glial cell differentiation" EXACT [] is_a: GO:0014015 ! positive regulation of gliogenesis is_a: GO:0045685 ! regulation of glial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0010001 ! positively regulates glial cell differentiation relationship: RO:0002213 GO:0010001 ! positively regulates glial cell differentiation [Term] id: GO:0045700 name: regulation of spermatid nuclear differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of spermatid nuclear differentiation." [GOC:go_curators] is_a: GO:0051239 ! regulation of multicellular organismal process is_a: GO:1903353 ! regulation of nucleus organization is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007289 ! regulates (processual) spermatid nucleus differentiation relationship: RO:0002211 GO:0007289 ! regulates (processual) spermatid nucleus differentiation [Term] id: GO:0045701 name: negative regulation of spermatid nuclear differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of spermatid nuclear differentiation." [GOC:go_curators] synonym: "down regulation of spermatid nuclear differentiation" EXACT [] synonym: "down-regulation of spermatid nuclear differentiation" EXACT [] synonym: "downregulation of spermatid nuclear differentiation" EXACT [] is_a: GO:0010639 ! negative regulation of organelle organization is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0045700 ! regulation of spermatid nuclear differentiation is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007289 ! negatively regulates spermatid nucleus differentiation relationship: RO:0002212 GO:0007289 ! negatively regulates spermatid nucleus differentiation [Term] id: GO:0045702 name: positive regulation of spermatid nuclear differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of spermatid nuclear differentiation." [GOC:go_curators] synonym: "up regulation of spermatid nuclear differentiation" EXACT [] synonym: "up-regulation of spermatid nuclear differentiation" EXACT [] synonym: "upregulation of spermatid nuclear differentiation" EXACT [] is_a: GO:0010638 ! positive regulation of organelle organization is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0045700 ! regulation of spermatid nuclear differentiation is_a: GO:2000243 ! positive regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007289 ! positively regulates spermatid nucleus differentiation relationship: RO:0002213 GO:0007289 ! positively regulates spermatid nucleus differentiation [Term] id: GO:0045719 name: negative regulation of glycogen biosynthetic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen." [GOC:go_curators] synonym: "down regulation of glycogen biosynthetic process" EXACT [] synonym: "down-regulation of glycogen biosynthetic process" EXACT [] synonym: "downregulation of glycogen biosynthetic process" EXACT [] synonym: "negative regulation of glycogen anabolism" EXACT [] synonym: "negative regulation of glycogen biosynthesis" EXACT [] synonym: "negative regulation of glycogen formation" EXACT [] synonym: "negative regulation of glycogen synthesis" EXACT [] is_a: GO:0005979 ! regulation of glycogen biosynthetic process is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process is_a: GO:0070874 ! negative regulation of glycogen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0005978 ! negatively regulates glycogen biosynthetic process relationship: RO:0002212 GO:0005978 ! negatively regulates glycogen biosynthetic process [Term] id: GO:0045721 name: negative regulation of gluconeogenesis namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of gluconeogenesis." [GOC:go_curators] synonym: "down regulation of gluconeogenesis" EXACT [] synonym: "down-regulation of gluconeogenesis" EXACT [] synonym: "downregulation of gluconeogenesis" EXACT [] is_a: GO:0006111 ! regulation of gluconeogenesis is_a: GO:0031327 ! negative regulation of cellular biosynthetic process is_a: GO:0045912 ! negative regulation of carbohydrate metabolic process is_a: GO:0062014 ! negative regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006094 ! negatively regulates gluconeogenesis relationship: RO:0002212 GO:0006094 ! negatively regulates gluconeogenesis [Term] id: GO:0045722 name: positive regulation of gluconeogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of gluconeogenesis." [GOC:go_curators] synonym: "up regulation of gluconeogenesis" EXACT [] synonym: "up-regulation of gluconeogenesis" EXACT [] synonym: "upregulation of gluconeogenesis" EXACT [] is_a: GO:0006111 ! regulation of gluconeogenesis is_a: GO:0010907 ! positive regulation of glucose metabolic process is_a: GO:0031328 ! positive regulation of cellular biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006094 ! positively regulates gluconeogenesis relationship: RO:0002213 GO:0006094 ! positively regulates gluconeogenesis [Term] id: GO:0045724 name: positive regulation of cilium assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the formation of a cilium." [GOC:cilia, GOC:go_curators] synonym: "up regulation of cilium assembly" EXACT [] synonym: "up-regulation of cilium assembly" EXACT [] synonym: "upregulation of cilium assembly" EXACT [] is_a: GO:0120034 ! positive regulation of plasma membrane bounded cell projection assembly is_a: GO:1902017 ! regulation of cilium assembly is_a: GO:1902117 ! positive regulation of organelle assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060271 ! positively regulates cilium assembly relationship: RO:0002213 GO:0060271 ! positively regulates cilium assembly [Term] id: GO:0045725 name: positive regulation of glycogen biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen." [GOC:go_curators] synonym: "positive regulation of glycogen anabolism" EXACT [] synonym: "positive regulation of glycogen biosynthesis" EXACT [] synonym: "positive regulation of glycogen formation" EXACT [] synonym: "positive regulation of glycogen synthesis" EXACT [] synonym: "up regulation of glycogen biosynthetic process" EXACT [] synonym: "up-regulation of glycogen biosynthetic process" EXACT [] synonym: "upregulation of glycogen biosynthetic process" EXACT [] is_a: GO:0005979 ! regulation of glycogen biosynthetic process is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process is_a: GO:0070875 ! positive regulation of glycogen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0005978 ! positively regulates glycogen biosynthetic process relationship: RO:0002213 GO:0005978 ! positively regulates glycogen biosynthetic process [Term] id: GO:0045727 name: positive regulation of translation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "positive regulation of protein anabolism" EXACT [] synonym: "positive regulation of protein biosynthesis" EXACT [] synonym: "positive regulation of protein biosynthetic process" EXACT [GOC:tb] synonym: "positive regulation of protein formation" EXACT [] synonym: "positive regulation of protein synthesis" EXACT [] synonym: "up regulation of protein biosynthetic process" EXACT [] synonym: "up-regulation of protein biosynthetic process" EXACT [] synonym: "upregulation of protein biosynthetic process" EXACT [] is_a: GO:0006417 ! regulation of translation is_a: GO:0010628 ! positive regulation of gene expression is_a: GO:0034250 ! positive regulation of amide metabolic process is_a: GO:0051247 ! positive regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006412 ! positively regulates translation relationship: RO:0002213 GO:0006412 ! positively regulates translation [Term] id: GO:0045732 name: positive regulation of protein catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds." [GOC:go_curators] synonym: "positive regulation of cellular protein breakdown" EXACT [GOC:TermGenie] synonym: "positive regulation of cellular protein catabolic process" EXACT [] synonym: "positive regulation of cellular protein catabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of cellular protein degradation" EXACT [GOC:TermGenie] synonym: "positive regulation of protein breakdown" EXACT [] synonym: "positive regulation of protein catabolism" EXACT [] synonym: "positive regulation of protein degradation" EXACT [] synonym: "up regulation of cellular protein breakdown" EXACT [GOC:TermGenie] synonym: "up regulation of cellular protein catabolic process" EXACT [GOC:TermGenie] synonym: "up regulation of cellular protein catabolism" EXACT [GOC:TermGenie] synonym: "up regulation of cellular protein degradation" EXACT [GOC:TermGenie] synonym: "up regulation of protein catabolic process" EXACT [] synonym: "up-regulation of cellular protein breakdown" EXACT [GOC:TermGenie] synonym: "up-regulation of cellular protein catabolic process" EXACT [GOC:TermGenie] synonym: "up-regulation of cellular protein catabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of cellular protein degradation" EXACT [GOC:TermGenie] synonym: "up-regulation of protein catabolic process" EXACT [] synonym: "upregulation of cellular protein breakdown" EXACT [GOC:TermGenie] synonym: "upregulation of cellular protein catabolic process" EXACT [GOC:TermGenie] synonym: "upregulation of cellular protein catabolism" EXACT [GOC:TermGenie] synonym: "upregulation of cellular protein degradation" EXACT [GOC:TermGenie] synonym: "upregulation of protein catabolic process" EXACT [] is_a: GO:0009896 ! positive regulation of catabolic process is_a: GO:0042176 ! regulation of protein catabolic process is_a: GO:0051247 ! positive regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030163 ! positively regulates protein catabolic process relationship: RO:0002213 GO:0030163 ! positively regulates protein catabolic process [Term] id: GO:0045733 name: acetate catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid." [GOC:go_curators] synonym: "acetate breakdown" EXACT [] synonym: "acetate catabolism" EXACT [] synonym: "acetate degradation" EXACT [] is_a: GO:0006083 ! acetate metabolic process is_a: GO:0072329 ! monocarboxylic acid catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:30089 ! has primary input acetate relationship: RO:0004009 CHEBI:30089 ! has primary input acetate [Term] id: GO:0045734 name: regulation of acetate catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid." [GOC:go_curators] synonym: "regulation of acetate breakdown" EXACT [] synonym: "regulation of acetate catabolism" EXACT [] synonym: "regulation of acetate degradation" EXACT [] is_a: GO:0010565 ! regulation of cellular ketone metabolic process is_a: GO:0031329 ! regulation of cellular catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0045733 ! regulates (processual) acetate catabolic process relationship: RO:0002211 GO:0045733 ! regulates (processual) acetate catabolic process [Term] id: GO:0045753 name: negative regulation of acetate catabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate." [GOC:go_curators] synonym: "down regulation of acetate catabolic process" EXACT [] synonym: "down-regulation of acetate catabolic process" EXACT [] synonym: "downregulation of acetate catabolic process" EXACT [] synonym: "negative regulation of acetate breakdown" EXACT [] synonym: "negative regulation of acetate catabolism" EXACT [] synonym: "negative regulation of acetate degradation" EXACT [] is_a: GO:0031330 ! negative regulation of cellular catabolic process is_a: GO:0045734 ! regulation of acetate catabolic process is_a: GO:0062014 ! negative regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0045733 ! negatively regulates acetate catabolic process relationship: RO:0002212 GO:0045733 ! negatively regulates acetate catabolic process [Term] id: GO:0045754 name: positive regulation of acetate catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate." [GOC:go_curators] synonym: "positive regulation of acetate breakdown" EXACT [] synonym: "positive regulation of acetate catabolism" EXACT [] synonym: "positive regulation of acetate degradation" EXACT [] synonym: "up regulation of acetate catabolic process" EXACT [] synonym: "up-regulation of acetate catabolic process" EXACT [] synonym: "upregulation of acetate catabolic process" EXACT [] is_a: GO:0031331 ! positive regulation of cellular catabolic process is_a: GO:0045734 ! regulation of acetate catabolic process is_a: GO:0062013 ! positive regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0045733 ! positively regulates acetate catabolic process relationship: RO:0002213 GO:0045733 ! positively regulates acetate catabolic process [Term] id: GO:0045759 name: negative regulation of action potential namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:go_curators] synonym: "down regulation of action potential" EXACT [] synonym: "down-regulation of action potential" EXACT [] synonym: "downregulation of action potential" EXACT [] is_a: GO:0048519 ! negative regulation of biological process is_a: GO:0098900 ! regulation of action potential intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001508 ! negatively regulates action potential relationship: RO:0002212 GO:0001508 ! negatively regulates action potential [Term] id: GO:0045760 name: positive regulation of action potential namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:go_curators] synonym: "up regulation of action potential" EXACT [] synonym: "up-regulation of action potential" EXACT [] synonym: "upregulation of action potential" EXACT [] is_a: GO:0048518 ! positive regulation of biological process is_a: GO:0098900 ! regulation of action potential intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001508 ! positively regulates action potential relationship: RO:0002213 GO:0001508 ! positively regulates action potential [Term] id: GO:0045763 name: negative regulation of cellular amino acid metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amino acid." [GOC:go_curators] synonym: "down regulation of amino acid metabolic process" EXACT [] synonym: "down-regulation of amino acid metabolic process" EXACT [] synonym: "downregulation of amino acid metabolic process" EXACT [] synonym: "negative regulation of amino acid metabolism" EXACT [] is_a: GO:0006521 ! regulation of cellular amino acid metabolic process is_a: GO:0033239 ! negative regulation of amine metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006520 ! negatively regulates amino acid metabolic process relationship: RO:0002212 GO:0006520 ! negatively regulates amino acid metabolic process [Term] id: GO:0045764 name: positive regulation of amino acid metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amino acid." [GOC:go_curators] synonym: "positive regulation of amino acid metabolism" EXACT [] synonym: "positive regulation of cellular amino acid metabolic process" EXACT [] synonym: "up regulation of amino acid metabolic process" EXACT [] synonym: "up-regulation of amino acid metabolic process" EXACT [] synonym: "upregulation of amino acid metabolic process" EXACT [] is_a: GO:0006521 ! regulation of cellular amino acid metabolic process is_a: GO:0033240 ! positive regulation of amine metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006520 ! positively regulates amino acid metabolic process relationship: RO:0002213 GO:0006520 ! positively regulates amino acid metabolic process [Term] id: GO:0045765 name: regulation of angiogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of angiogenesis." [GOC:go_curators] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis is_a: GO:1901342 ! regulation of vasculature development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001525 ! regulates (processual) angiogenesis relationship: RO:0002211 GO:0001525 ! regulates (processual) angiogenesis [Term] id: GO:0045766 name: positive regulation of angiogenesis namespace: biological_process def: "Any process that activates or increases angiogenesis." [GOC:go_curators] synonym: "up regulation of angiogenesis" EXACT [] synonym: "up-regulation of angiogenesis" EXACT [] synonym: "upregulation of angiogenesis" EXACT [] is_a: GO:0045765 ! regulation of angiogenesis is_a: GO:1904018 ! positive regulation of vasculature development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001525 ! positively regulates angiogenesis relationship: RO:0002213 GO:0001525 ! positively regulates angiogenesis [Term] id: GO:0045769 name: negative regulation of asymmetric cell division namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of asymmetric cell division." [GOC:go_curators] synonym: "down regulation of asymmetric cell division" EXACT [] synonym: "down-regulation of asymmetric cell division" EXACT [] synonym: "downregulation of asymmetric cell division" EXACT [] is_a: GO:0009786 ! regulation of asymmetric cell division is_a: GO:0051782 ! negative regulation of cell division intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0008356 ! negatively regulates asymmetric cell division relationship: RO:0002212 GO:0008356 ! negatively regulates asymmetric cell division [Term] id: GO:0045770 name: positive regulation of asymmetric cell division namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of asymmetric cell division." [GOC:go_curators] synonym: "up regulation of asymmetric cell division" EXACT [] synonym: "up-regulation of asymmetric cell division" EXACT [] synonym: "upregulation of asymmetric cell division" EXACT [] is_a: GO:0009786 ! regulation of asymmetric cell division is_a: GO:0051781 ! positive regulation of cell division intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0008356 ! positively regulates asymmetric cell division relationship: RO:0002213 GO:0008356 ! positively regulates asymmetric cell division [Term] id: GO:0045778 name: positive regulation of ossification namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance." [GOC:go_curators] synonym: "positive regulation of bone biosynthesis" EXACT [] synonym: "positive regulation of bone formation" EXACT [] synonym: "up regulation of ossification" EXACT [] synonym: "up-regulation of ossification" EXACT [] synonym: "upregulation of ossification" EXACT [] is_a: GO:0030278 ! regulation of ossification is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001503 ! positively regulates ossification relationship: RO:0002213 GO:0001503 ! positively regulates ossification [Term] id: GO:0045785 name: positive regulation of cell adhesion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell adhesion." [GOC:go_curators] synonym: "up regulation of cell adhesion" EXACT [] synonym: "up-regulation of cell adhesion" EXACT [] synonym: "upregulation of cell adhesion" EXACT [] is_a: GO:0030155 ! regulation of cell adhesion is_a: GO:0048522 ! positive regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007155 ! positively regulates cell adhesion relationship: RO:0002213 GO:0007155 ! positively regulates cell adhesion [Term] id: GO:0045786 name: negative regulation of cell cycle namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "down regulation of progression through cell cycle" EXACT [] synonym: "down-regulation of progression through cell cycle" EXACT [] synonym: "downregulation of progression through cell cycle" EXACT [] synonym: "negative regulation of cell cycle progression" EXACT [] synonym: "negative regulation of progression through cell cycle" EXACT [] is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:0051726 ! regulation of cell cycle intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007049 ! negatively regulates cell cycle relationship: RO:0002212 GO:0007049 ! negatively regulates cell cycle [Term] id: GO:0045787 name: positive regulation of cell cycle namespace: biological_process def: "Any process that activates or increases the rate or extent of progression through the cell cycle." [GOC:go_curators] synonym: "positive regulation of cell cycle progression" EXACT [] synonym: "positive regulation of progression through cell cycle" EXACT [GOC:dph, GOC:tb] synonym: "up regulation of progression through cell cycle" EXACT [] synonym: "up-regulation of progression through cell cycle" EXACT [] synonym: "upregulation of progression through cell cycle" EXACT [] is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:0051726 ! regulation of cell cycle intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007049 ! positively regulates cell cycle relationship: RO:0002213 GO:0007049 ! positively regulates cell cycle [Term] id: GO:0045804 name: negative regulation of eclosion namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of eclosion." [GOC:go_curators] synonym: "down regulation of eclosion" EXACT [] synonym: "down-regulation of eclosion" EXACT [] synonym: "downregulation of eclosion" EXACT [] is_a: GO:0007563 ! regulation of eclosion is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007562 ! negatively regulates eclosion relationship: RO:0002212 GO:0007562 ! negatively regulates eclosion [Term] id: GO:0045805 name: positive regulation of eclosion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of eclosion." [GOC:go_curators] synonym: "up regulation of eclosion" EXACT [] synonym: "up-regulation of eclosion" EXACT [] synonym: "upregulation of eclosion" EXACT [] is_a: GO:0007563 ! regulation of eclosion is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007562 ! positively regulates eclosion relationship: RO:0002213 GO:0007562 ! positively regulates eclosion [Term] id: GO:0045806 name: negative regulation of endocytosis namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of endocytosis." [GOC:go_curators] synonym: "down regulation of endocytosis" EXACT [] synonym: "down-regulation of endocytosis" EXACT [] synonym: "downregulation of endocytosis" EXACT [] is_a: GO:0030100 ! regulation of endocytosis is_a: GO:0051051 ! negative regulation of transport is_a: GO:0051129 ! negative regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006897 ! negatively regulates endocytosis relationship: RO:0002212 GO:0006897 ! negatively regulates endocytosis [Term] id: GO:0045807 name: positive regulation of endocytosis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of endocytosis." [GOC:go_curators] synonym: "up regulation of endocytosis" EXACT [] synonym: "up-regulation of endocytosis" EXACT [] synonym: "upregulation of endocytosis" EXACT [] is_a: GO:0030100 ! regulation of endocytosis is_a: GO:0051050 ! positive regulation of transport is_a: GO:0051130 ! positive regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006897 ! positively regulates endocytosis relationship: RO:0002213 GO:0006897 ! positively regulates endocytosis [Term] id: GO:0045818 name: negative regulation of glycogen catabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen." [GOC:go_curators] synonym: "down regulation of glycogen catabolic process" EXACT [] synonym: "down-regulation of glycogen catabolic process" EXACT [] synonym: "downregulation of glycogen catabolic process" EXACT [] synonym: "negative regulation of glycogen breakdown" EXACT [] synonym: "negative regulation of glycogen catabolism" EXACT [] synonym: "negative regulation of glycogen degradation" EXACT [] synonym: "negative regulation of glycogenolysis" EXACT [GOC:sl] is_a: GO:0005981 ! regulation of glycogen catabolic process is_a: GO:0031330 ! negative regulation of cellular catabolic process is_a: GO:0070874 ! negative regulation of glycogen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0005980 ! negatively regulates glycogen catabolic process relationship: RO:0002212 GO:0005980 ! negatively regulates glycogen catabolic process [Term] id: GO:0045819 name: positive regulation of glycogen catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen." [GOC:go_curators] synonym: "positive regulation of glycogen breakdown" EXACT [] synonym: "positive regulation of glycogen catabolism" EXACT [] synonym: "positive regulation of glycogen degradation" EXACT [] synonym: "positive regulation of glycogenolysis" EXACT [GOC:sl] synonym: "up regulation of glycogen catabolic process" EXACT [] synonym: "up-regulation of glycogen catabolic process" EXACT [] synonym: "upregulation of glycogen catabolic process" EXACT [] is_a: GO:0005981 ! regulation of glycogen catabolic process is_a: GO:0031331 ! positive regulation of cellular catabolic process is_a: GO:0070875 ! positive regulation of glycogen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0005980 ! positively regulates glycogen catabolic process relationship: RO:0002213 GO:0005980 ! positively regulates glycogen catabolic process [Term] id: GO:0045822 name: negative regulation of heart contraction namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction." [GOC:go_curators] synonym: "down regulation of heart contraction" EXACT [] synonym: "down-regulation of heart contraction" EXACT [] synonym: "downregulation of heart contraction" EXACT [] is_a: GO:0008016 ! regulation of heart contraction is_a: GO:1903523 ! negative regulation of blood circulation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060047 ! negatively regulates heart contraction relationship: RO:0002212 GO:0060047 ! negatively regulates heart contraction [Term] id: GO:0045823 name: positive regulation of heart contraction namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of heart contraction." [GOC:go_curators] synonym: "positive regulation of cardiac contraction" EXACT [] synonym: "up regulation of heart contraction" EXACT [] synonym: "up-regulation of heart contraction" EXACT [] synonym: "upregulation of heart contraction" EXACT [] is_a: GO:0008016 ! regulation of heart contraction is_a: GO:1903524 ! positive regulation of blood circulation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060047 ! positively regulates heart contraction relationship: RO:0002213 GO:0060047 ! positively regulates heart contraction [Term] id: GO:0045833 name: negative regulation of lipid metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipids." [GOC:go_curators] synonym: "down regulation of lipid metabolic process" EXACT [] synonym: "down-regulation of lipid metabolic process" EXACT [] synonym: "downregulation of lipid metabolic process" EXACT [] synonym: "negative regulation of lipid metabolism" EXACT [] is_a: GO:0009892 ! negative regulation of metabolic process is_a: GO:0019216 ! regulation of lipid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006629 ! negatively regulates lipid metabolic process relationship: RO:0002212 GO:0006629 ! negatively regulates lipid metabolic process [Term] id: GO:0045834 name: positive regulation of lipid metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipids." [GOC:go_curators] synonym: "positive regulation of lipid metabolism" EXACT [] synonym: "up regulation of lipid metabolic process" EXACT [] synonym: "up-regulation of lipid metabolic process" EXACT [] synonym: "upregulation of lipid metabolic process" EXACT [] is_a: GO:0009893 ! positive regulation of metabolic process is_a: GO:0019216 ! regulation of lipid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006629 ! positively regulates lipid metabolic process relationship: RO:0002213 GO:0006629 ! positively regulates lipid metabolic process [Term] id: GO:0045835 name: negative regulation of meiotic nuclear division namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis." [GOC:go_curators] synonym: "down regulation of meiosis" EXACT [] synonym: "down-regulation of meiosis" EXACT [] synonym: "downregulation of meiosis" EXACT [] synonym: "negative regulation of meiosis" EXACT [] is_a: GO:0010948 ! negative regulation of cell cycle process is_a: GO:0040020 ! regulation of meiotic nuclear division is_a: GO:0051447 ! negative regulation of meiotic cell cycle is_a: GO:0051784 ! negative regulation of nuclear division intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0140013 ! negatively regulates meiotic nuclear division relationship: RO:0002212 GO:0140013 ! negatively regulates meiotic nuclear division [Term] id: GO:0045836 name: positive regulation of meiotic nuclear division namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of meiosis." [GOC:go_curators] synonym: "positive regulation of meiosis" EXACT [] synonym: "up regulation of meiosis" EXACT [] synonym: "up-regulation of meiosis" EXACT [] synonym: "upregulation of meiosis" EXACT [] is_a: GO:0040020 ! regulation of meiotic nuclear division is_a: GO:0051446 ! positive regulation of meiotic cell cycle is_a: GO:0051785 ! positive regulation of nuclear division is_a: GO:0090068 ! positive regulation of cell cycle process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0140013 ! positively regulates meiotic nuclear division relationship: RO:0002213 GO:0140013 ! positively regulates meiotic nuclear division [Term] id: GO:0045839 name: negative regulation of mitotic nuclear division namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "down regulation of mitosis" EXACT [] synonym: "down-regulation of mitosis" EXACT [] synonym: "downregulation of mitosis" EXACT [] synonym: "negative regulation of mitosis" EXACT [] is_a: GO:0007088 ! regulation of mitotic nuclear division is_a: GO:0010948 ! negative regulation of cell cycle process is_a: GO:0045930 ! negative regulation of mitotic cell cycle is_a: GO:0051784 ! negative regulation of nuclear division intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0140014 ! negatively regulates mitotic nuclear division relationship: RO:0002212 GO:0140014 ! negatively regulates mitotic nuclear division [Term] id: GO:0045840 name: positive regulation of mitotic nuclear division namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mitosis." [GOC:go_curators] synonym: "positive regulation of mitosis" EXACT [] synonym: "up regulation of mitosis" EXACT [] synonym: "up-regulation of mitosis" EXACT [] synonym: "upregulation of mitosis" EXACT [] is_a: GO:0007088 ! regulation of mitotic nuclear division is_a: GO:0051785 ! positive regulation of nuclear division is_a: GO:0090068 ! positive regulation of cell cycle process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0140014 ! positively regulates mitotic nuclear division relationship: RO:0002213 GO:0140014 ! positively regulates mitotic nuclear division [Term] id: GO:0045843 name: negative regulation of striated muscle tissue development namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle development." [GOC:go_curators] synonym: "down regulation of striated muscle development" EXACT [] synonym: "down-regulation of striated muscle development" EXACT [] synonym: "downregulation of striated muscle development" EXACT [] is_a: GO:0016202 ! regulation of striated muscle tissue development is_a: GO:0048635 ! negative regulation of muscle organ development is_a: GO:1901862 ! negative regulation of muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0014706 ! negatively regulates striated muscle tissue development relationship: RO:0002212 GO:0014706 ! negatively regulates striated muscle tissue development [Term] id: GO:0045844 name: positive regulation of striated muscle tissue development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of striated muscle development." [GOC:go_curators] synonym: "up regulation of striated muscle development" EXACT [] synonym: "up-regulation of striated muscle development" EXACT [] synonym: "upregulation of striated muscle development" EXACT [] is_a: GO:0016202 ! regulation of striated muscle tissue development is_a: GO:0048636 ! positive regulation of muscle organ development is_a: GO:1901863 ! positive regulation of muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0014706 ! positively regulates striated muscle tissue development relationship: RO:0002213 GO:0014706 ! positively regulates striated muscle tissue development [Term] id: GO:0045900 name: negative regulation of translational elongation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of translational elongation." [GOC:go_curators] synonym: "down regulation of translational elongation" EXACT [] synonym: "down-regulation of translational elongation" EXACT [] synonym: "downregulation of translational elongation" EXACT [] is_a: GO:0006448 ! regulation of translational elongation is_a: GO:0017148 ! negative regulation of translation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006414 ! negatively regulates translational elongation relationship: RO:0002212 GO:0006414 ! negatively regulates translational elongation [Term] id: GO:0045901 name: positive regulation of translational elongation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of translational elongation." [GOC:go_curators] synonym: "up regulation of translational elongation" EXACT [] synonym: "up-regulation of translational elongation" EXACT [] synonym: "upregulation of translational elongation" EXACT [] is_a: GO:0006448 ! regulation of translational elongation is_a: GO:0045727 ! positive regulation of translation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006414 ! positively regulates translational elongation relationship: RO:0002213 GO:0006414 ! positively regulates translational elongation [Term] id: GO:0045904 name: negative regulation of translational termination namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of translational termination." [GOC:go_curators] synonym: "down regulation of translational termination" EXACT [] synonym: "down-regulation of translational termination" EXACT [] synonym: "downregulation of translational termination" EXACT [] is_a: GO:0006449 ! regulation of translational termination is_a: GO:0017148 ! negative regulation of translation is_a: GO:0043242 ! negative regulation of protein-containing complex disassembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006415 ! negatively regulates translational termination relationship: RO:0002212 GO:0006415 ! negatively regulates translational termination [Term] id: GO:0045905 name: positive regulation of translational termination namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of translational termination." [GOC:go_curators] synonym: "up regulation of translational termination" EXACT [] synonym: "up-regulation of translational termination" EXACT [] synonym: "upregulation of translational termination" EXACT [] is_a: GO:0006449 ! regulation of translational termination is_a: GO:0043243 ! positive regulation of protein-containing complex disassembly is_a: GO:0045727 ! positive regulation of translation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006415 ! positively regulates translational termination relationship: RO:0002213 GO:0006415 ! positively regulates translational termination [Term] id: GO:0045912 name: negative regulation of carbohydrate metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate." [GOC:go_curators] synonym: "down regulation of carbohydrate metabolic process" EXACT [] synonym: "down-regulation of carbohydrate metabolic process" EXACT [] synonym: "downregulation of carbohydrate metabolic process" EXACT [] synonym: "negative regulation of carbohydrate metabolism" EXACT [] is_a: GO:0006109 ! regulation of carbohydrate metabolic process is_a: GO:0009892 ! negative regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0005975 ! negatively regulates carbohydrate metabolic process relationship: RO:0002212 GO:0005975 ! negatively regulates carbohydrate metabolic process [Term] id: GO:0045913 name: positive regulation of carbohydrate metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate." [GOC:go_curators] synonym: "positive regulation of carbohydrate metabolism" EXACT [] synonym: "up regulation of carbohydrate metabolic process" EXACT [] synonym: "up-regulation of carbohydrate metabolic process" EXACT [] synonym: "upregulation of carbohydrate metabolic process" EXACT [] is_a: GO:0006109 ! regulation of carbohydrate metabolic process is_a: GO:0009893 ! positive regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0005975 ! positively regulates carbohydrate metabolic process relationship: RO:0002213 GO:0005975 ! positively regulates carbohydrate metabolic process [Term] id: GO:0045914 name: negative regulation of catecholamine metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catecholamine." [GOC:go_curators] synonym: "down regulation of catecholamine metabolic process" EXACT [] synonym: "down-regulation of catecholamine metabolic process" EXACT [] synonym: "downregulation of catecholamine metabolic process" EXACT [] synonym: "negative regulation of catecholamine metabolism" EXACT [] is_a: GO:0031324 ! negative regulation of cellular metabolic process is_a: GO:0033239 ! negative regulation of amine metabolic process is_a: GO:0042069 ! regulation of catecholamine metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006584 ! negatively regulates catecholamine metabolic process relationship: RO:0002212 GO:0006584 ! negatively regulates catecholamine metabolic process [Term] id: GO:0045915 name: positive regulation of catecholamine metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catecholamine." [GOC:go_curators] synonym: "positive regulation of catecholamine metabolism" EXACT [] synonym: "up regulation of catecholamine metabolic process" EXACT [] synonym: "up-regulation of catecholamine metabolic process" EXACT [] synonym: "upregulation of catecholamine metabolic process" EXACT [] is_a: GO:0031325 ! positive regulation of cellular metabolic process is_a: GO:0033240 ! positive regulation of amine metabolic process is_a: GO:0042069 ! regulation of catecholamine metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006584 ! positively regulates catecholamine metabolic process relationship: RO:0002213 GO:0006584 ! positively regulates catecholamine metabolic process [Term] id: GO:0045920 name: negative regulation of exocytosis namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of exocytosis." [GOC:go_curators] synonym: "down regulation of exocytosis" EXACT [] synonym: "down-regulation of exocytosis" EXACT [] synonym: "downregulation of exocytosis" EXACT [] is_a: GO:0017157 ! regulation of exocytosis is_a: GO:1903531 ! negative regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006887 ! negatively regulates exocytosis relationship: RO:0002212 GO:0006887 ! negatively regulates exocytosis [Term] id: GO:0045921 name: positive regulation of exocytosis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of exocytosis." [GOC:go_curators] synonym: "up regulation of exocytosis" EXACT [] synonym: "up-regulation of exocytosis" EXACT [] synonym: "upregulation of exocytosis" EXACT [] is_a: GO:0017157 ! regulation of exocytosis is_a: GO:1903532 ! positive regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006887 ! positively regulates exocytosis relationship: RO:0002213 GO:0006887 ! positively regulates exocytosis [Term] id: GO:0045926 name: negative regulation of growth namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism." [GOC:go_curators] synonym: "down regulation of growth" EXACT [] synonym: "down-regulation of growth" EXACT [] synonym: "downregulation of growth" EXACT [] is_a: GO:0040008 ! regulation of growth is_a: GO:0048519 ! negative regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0040007 ! negatively regulates growth relationship: RO:0002212 GO:0040007 ! negatively regulates growth [Term] id: GO:0045927 name: positive regulation of growth namespace: biological_process def: "Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism." [GOC:go_curators] synonym: "up regulation of growth" EXACT [] synonym: "up-regulation of growth" EXACT [] synonym: "upregulation of growth" EXACT [] is_a: GO:0040008 ! regulation of growth is_a: GO:0048518 ! positive regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0040007 ! positively regulates growth relationship: RO:0002213 GO:0040007 ! positively regulates growth [Term] id: GO:0045930 name: negative regulation of mitotic cell cycle namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of progression through the mitotic cell cycle." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "down regulation of progression through mitotic cell cycle" EXACT [] synonym: "down-regulation of progression through mitotic cell cycle" EXACT [] synonym: "downregulation of progression through mitotic cell cycle" EXACT [] synonym: "negative regulation of mitotic cell cycle progression" EXACT [] synonym: "negative regulation of progression through mitotic cell cycle" EXACT [GOC:dph, GOC:tb] is_a: GO:0007346 ! regulation of mitotic cell cycle is_a: GO:0045786 ! negative regulation of cell cycle intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0000278 ! negatively regulates mitotic cell cycle relationship: RO:0002212 GO:0000278 ! negatively regulates mitotic cell cycle [Term] id: GO:0045931 name: positive regulation of mitotic cell cycle namespace: biological_process def: "Any process that activates or increases the rate or extent of progression through the mitotic cell cycle." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "positive regulation of mitotic cell cycle progression" EXACT [] synonym: "positive regulation of progression through mitotic cell cycle" EXACT [GOC:dph, GOC:tb] synonym: "up regulation of progression through mitotic cell cycle" EXACT [] synonym: "up-regulation of progression through mitotic cell cycle" EXACT [] synonym: "upregulation of progression through mitotic cell cycle" EXACT [] is_a: GO:0007346 ! regulation of mitotic cell cycle is_a: GO:0045787 ! positive regulation of cell cycle intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0000278 ! positively regulates mitotic cell cycle relationship: RO:0002213 GO:0000278 ! positively regulates mitotic cell cycle [Term] id: GO:0045932 name: negative regulation of muscle contraction namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of muscle contraction." [GOC:go_curators] synonym: "down regulation of muscle contraction" EXACT [] synonym: "down-regulation of muscle contraction" EXACT [] synonym: "downregulation of muscle contraction" EXACT [] is_a: GO:0006937 ! regulation of muscle contraction is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006936 ! negatively regulates muscle contraction relationship: RO:0002212 GO:0006936 ! negatively regulates muscle contraction [Term] id: GO:0045933 name: positive regulation of muscle contraction namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of muscle contraction." [GOC:go_curators] synonym: "up regulation of muscle contraction" EXACT [] synonym: "up-regulation of muscle contraction" EXACT [] synonym: "upregulation of muscle contraction" EXACT [] is_a: GO:0006937 ! regulation of muscle contraction is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006936 ! positively regulates muscle contraction relationship: RO:0002213 GO:0006936 ! positively regulates muscle contraction [Term] id: GO:0045934 name: negative regulation of nucleobase-containing compound metabolic process namespace: biological_process def: "Any cellular process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:go_curators] synonym: "down regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT [] synonym: "down-regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT [] synonym: "downregulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT [] synonym: "negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism" EXACT [] is_a: GO:0019219 ! regulation of nucleobase-containing compound metabolic process is_a: GO:0031324 ! negative regulation of cellular metabolic process is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006139 ! negatively regulates nucleobase-containing compound metabolic process relationship: RO:0002212 GO:0006139 ! negatively regulates nucleobase-containing compound metabolic process [Term] id: GO:0045935 name: positive regulation of nucleobase-containing compound metabolic process namespace: biological_process def: "Any cellular process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:go_curators] synonym: "positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism" EXACT [] synonym: "up regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT [] synonym: "up-regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT [] synonym: "upregulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT [] is_a: GO:0019219 ! regulation of nucleobase-containing compound metabolic process is_a: GO:0031325 ! positive regulation of cellular metabolic process is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006139 ! positively regulates nucleobase-containing compound metabolic process relationship: RO:0002213 GO:0006139 ! positively regulates nucleobase-containing compound metabolic process [Term] id: GO:0045936 name: negative regulation of phosphate metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates." [GOC:go_curators] synonym: "down regulation of phosphate metabolic process" EXACT [] synonym: "down-regulation of phosphate metabolic process" EXACT [] synonym: "downregulation of phosphate metabolic process" EXACT [] synonym: "negative regulation of phosphate metabolism" EXACT [] is_a: GO:0010563 ! negative regulation of phosphorus metabolic process is_a: GO:0019220 ! regulation of phosphate metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006796 ! negatively regulates phosphate-containing compound metabolic process relationship: RO:0002212 GO:0006796 ! negatively regulates phosphate-containing compound metabolic process [Term] id: GO:0045937 name: positive regulation of phosphate metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates." [GOC:go_curators] synonym: "positive regulation of phosphate metabolism" EXACT [] synonym: "up regulation of phosphate metabolic process" EXACT [] synonym: "up-regulation of phosphate metabolic process" EXACT [] synonym: "upregulation of phosphate metabolic process" EXACT [] is_a: GO:0010562 ! positive regulation of phosphorus metabolic process is_a: GO:0019220 ! regulation of phosphate metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006796 ! positively regulates phosphate-containing compound metabolic process relationship: RO:0002213 GO:0006796 ! positively regulates phosphate-containing compound metabolic process [Term] id: GO:0045939 name: negative regulation of steroid metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving steroids." [GOC:go_curators] synonym: "down regulation of steroid metabolic process" EXACT [] synonym: "down-regulation of steroid metabolic process" EXACT [] synonym: "downregulation of steroid metabolic process" EXACT [] synonym: "negative regulation of steroid metabolism" EXACT [] is_a: GO:0019218 ! regulation of steroid metabolic process is_a: GO:0045833 ! negative regulation of lipid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0008202 ! negatively regulates steroid metabolic process relationship: RO:0002212 GO:0008202 ! negatively regulates steroid metabolic process [Term] id: GO:0045940 name: positive regulation of steroid metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving steroids." [GOC:go_curators] synonym: "positive regulation of steroid metabolism" EXACT [] synonym: "up regulation of steroid metabolic process" EXACT [] synonym: "up-regulation of steroid metabolic process" EXACT [] synonym: "upregulation of steroid metabolic process" EXACT [] is_a: GO:0019218 ! regulation of steroid metabolic process is_a: GO:0045834 ! positive regulation of lipid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0008202 ! positively regulates steroid metabolic process relationship: RO:0002213 GO:0008202 ! positively regulates steroid metabolic process [Term] id: GO:0045947 name: negative regulation of translational initiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of translational initiation." [GOC:go_curators] synonym: "down regulation of translational initiation" EXACT [] synonym: "down-regulation of translational initiation" EXACT [] synonym: "downregulation of translational initiation" EXACT [] is_a: GO:0006446 ! regulation of translational initiation is_a: GO:0017148 ! negative regulation of translation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006413 ! negatively regulates translational initiation relationship: RO:0002212 GO:0006413 ! negatively regulates translational initiation [Term] id: GO:0045948 name: positive regulation of translational initiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of translational initiation." [GOC:go_curators] synonym: "up regulation of translational initiation" EXACT [] synonym: "up-regulation of translational initiation" EXACT [] synonym: "upregulation of translational initiation" EXACT [] is_a: GO:0006446 ! regulation of translational initiation is_a: GO:0045727 ! positive regulation of translation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006413 ! positively regulates translational initiation relationship: RO:0002213 GO:0006413 ! positively regulates translational initiation [Term] id: GO:0045986 name: negative regulation of smooth muscle contraction namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle contraction." [GOC:go_curators] synonym: "down regulation of smooth muscle contraction" EXACT [] synonym: "down-regulation of smooth muscle contraction" EXACT [] synonym: "downregulation of smooth muscle contraction" EXACT [] is_a: GO:0006940 ! regulation of smooth muscle contraction is_a: GO:0045932 ! negative regulation of muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006939 ! negatively regulates smooth muscle contraction relationship: RO:0002212 GO:0006939 ! negatively regulates smooth muscle contraction [Term] id: GO:0045987 name: positive regulation of smooth muscle contraction namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of smooth muscle contraction." [GOC:go_curators] synonym: "up regulation of smooth muscle contraction" EXACT [] synonym: "up-regulation of smooth muscle contraction" EXACT [] synonym: "upregulation of smooth muscle contraction" EXACT [] is_a: GO:0006940 ! regulation of smooth muscle contraction is_a: GO:0045933 ! positive regulation of muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006939 ! positively regulates smooth muscle contraction relationship: RO:0002213 GO:0006939 ! positively regulates smooth muscle contraction [Term] id: GO:0045988 name: negative regulation of striated muscle contraction namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle contraction." [GOC:go_curators] synonym: "down regulation of striated muscle contraction" EXACT [] synonym: "down-regulation of striated muscle contraction" EXACT [] synonym: "downregulation of striated muscle contraction" EXACT [] is_a: GO:0006942 ! regulation of striated muscle contraction is_a: GO:0045932 ! negative regulation of muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006941 ! negatively regulates striated muscle contraction relationship: RO:0002212 GO:0006941 ! negatively regulates striated muscle contraction [Term] id: GO:0045989 name: positive regulation of striated muscle contraction namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of striated muscle contraction." [GOC:go_curators] synonym: "up regulation of striated muscle contraction" EXACT [] synonym: "up-regulation of striated muscle contraction" EXACT [] synonym: "upregulation of striated muscle contraction" EXACT [] is_a: GO:0006942 ! regulation of striated muscle contraction is_a: GO:0045933 ! positive regulation of muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006941 ! positively regulates striated muscle contraction relationship: RO:0002213 GO:0006941 ! positively regulates striated muscle contraction [Term] id: GO:0045992 name: negative regulation of embryonic development namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of embryonic development." [GOC:go_curators] synonym: "down regulation of embryonic development" EXACT [] synonym: "down-regulation of embryonic development" EXACT [] synonym: "downregulation of embryonic development" EXACT [] is_a: GO:0045995 ! regulation of embryonic development is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0009790 ! negatively regulates embryo development relationship: RO:0002212 GO:0009790 ! negatively regulates embryo development [Term] id: GO:0045995 name: regulation of embryonic development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of embryonic development." [GOC:go_curators] is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0009790 ! regulates (processual) embryo development relationship: RO:0002211 GO:0009790 ! regulates (processual) embryo development [Term] id: GO:0046013 name: regulation of T cell homeostatic proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of resting T cell proliferation." [GOC:go_curators] synonym: "regulation of resting T cell proliferation" EXACT [] synonym: "regulation of T lymphocyte homeostatic proliferation" EXACT [] synonym: "regulation of T-cell homeostatic proliferation" EXACT [] synonym: "regulation of T-lymphocyte homeostatic proliferation" EXACT [] is_a: GO:0042129 ! regulation of T cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001777 ! regulates (processual) T cell homeostatic proliferation relationship: RO:0002211 GO:0001777 ! regulates (processual) T cell homeostatic proliferation [Term] id: GO:0046014 name: negative regulation of T cell homeostatic proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of resting T cell proliferation." [GOC:go_curators] synonym: "down regulation of T cell homeostatic proliferation" EXACT [] synonym: "down-regulation of T cell homeostatic proliferation" EXACT [] synonym: "downregulation of T cell homeostatic proliferation" EXACT [] synonym: "negative regulation of resting T cell proliferation" EXACT [] synonym: "negative regulation of T lymphocyte homeostatic proliferation" EXACT [] synonym: "negative regulation of T-cell homeostatic proliferation" EXACT [] synonym: "negative regulation of T-lymphocyte homeostatic proliferation" EXACT [] is_a: GO:0042130 ! negative regulation of T cell proliferation is_a: GO:0046013 ! regulation of T cell homeostatic proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001777 ! negatively regulates T cell homeostatic proliferation relationship: RO:0002212 GO:0001777 ! negatively regulates T cell homeostatic proliferation [Term] id: GO:0046112 name: nucleobase biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid." [GOC:ai] synonym: "nucleobase anabolism" EXACT [] synonym: "nucleobase biosynthesis" EXACT [] synonym: "nucleobase formation" EXACT [] synonym: "nucleobase synthesis" EXACT [] is_a: GO:0009112 ! nucleobase metabolic process is_a: GO:0018130 ! heterocycle biosynthetic process is_a: GO:1901362 ! organic cyclic compound biosynthetic process is_a: GO:1901566 ! organonitrogen compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:18282 ! has primary output nucleobase relationship: RO:0004008 CHEBI:18282 ! has primary output nucleobase [Term] id: GO:0046113 name: nucleobase catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid." [GOC:ai] synonym: "nucleobase breakdown" EXACT [] synonym: "nucleobase catabolism" EXACT [] synonym: "nucleobase degradation" EXACT [] is_a: GO:0009112 ! nucleobase metabolic process is_a: GO:0046700 ! heterocycle catabolic process is_a: GO:1901361 ! organic cyclic compound catabolic process is_a: GO:1901565 ! organonitrogen compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:18282 ! has primary input nucleobase relationship: RO:0004009 CHEBI:18282 ! has primary input nucleobase [Term] id: GO:0046189 name: phenol-containing compound biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring." [GOC:ai] synonym: "phenol-containing compound anabolism" EXACT [] synonym: "phenol-containing compound biosynthesis" EXACT [] synonym: "phenol-containing compound formation" EXACT [] synonym: "phenol-containing compound synthesis" EXACT [] is_a: GO:0018958 ! phenol-containing compound metabolic process is_a: GO:0019438 ! aromatic compound biosynthetic process is_a: GO:1901362 ! organic cyclic compound biosynthetic process is_a: GO:1901617 ! organic hydroxy compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:33853 ! has primary output phenols relationship: RO:0004008 CHEBI:33853 ! has primary output phenols [Term] id: GO:0046219 name: indolalkylamine biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group." [GOC:curators] synonym: "indolalkylamine anabolism" EXACT [] synonym: "indolalkylamine biosynthesis" EXACT [] synonym: "indolalkylamine formation" EXACT [] synonym: "indolalkylamine synthesis" EXACT [] is_a: GO:0006586 ! indolalkylamine metabolic process is_a: GO:0042401 ! biogenic amine biosynthetic process is_a: GO:0042435 ! indole-containing compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:38631 ! has primary output aminoalkylindole relationship: RO:0004008 CHEBI:38631 ! has primary output aminoalkylindole [Term] id: GO:0046348 name: amino sugar catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of any amino sugar, sugars containing an amino group in place of a hydroxyl group." [GOC:curators] synonym: "amino sugar breakdown" EXACT [] synonym: "amino sugar catabolism" EXACT [] synonym: "amino sugar degradation" EXACT [] synonym: "aminosaccharide catabolic process" EXACT [] synonym: "aminosaccharide catabolism" EXACT [] is_a: GO:0006040 ! amino sugar metabolic process is_a: GO:1901136 ! carbohydrate derivative catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:28963 ! has primary input amino sugar relationship: RO:0004009 CHEBI:28963 ! has primary input amino sugar [Term] id: GO:0046349 name: amino sugar biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of any amino sugar, sugars containing an amino group in place of a hydroxyl group." [GOC:curators] synonym: "amino sugar anabolism" EXACT [] synonym: "amino sugar biosynthesis" EXACT [] synonym: "amino sugar formation" EXACT [] synonym: "amino sugar synthesis" EXACT [] synonym: "aminosaccharide biosynthesis" EXACT [] synonym: "aminosaccharide biosynthetic process" EXACT [] is_a: GO:0006040 ! amino sugar metabolic process is_a: GO:1901137 ! carbohydrate derivative biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:28963 ! has primary output amino sugar relationship: RO:0004008 CHEBI:28963 ! has primary output amino sugar [Term] id: GO:0046364 name: monosaccharide biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms." [ISBN:0198506732] synonym: "monosaccharide anabolism" EXACT [] synonym: "monosaccharide biosynthesis" EXACT [] synonym: "monosaccharide formation" EXACT [] synonym: "monosaccharide synthesis" EXACT [] is_a: GO:0005996 ! monosaccharide metabolic process is_a: GO:0016051 ! carbohydrate biosynthetic process is_a: GO:0044283 ! small molecule biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:35381 ! has primary output monosaccharide relationship: RO:0004008 CHEBI:35381 ! has primary output monosaccharide [Term] id: GO:0046365 name: monosaccharide catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms." [ISBN:0198506732] synonym: "monosaccharide breakdown" EXACT [] synonym: "monosaccharide catabolism" EXACT [] synonym: "monosaccharide degradation" EXACT [] is_a: GO:0005996 ! monosaccharide metabolic process is_a: GO:0016052 ! carbohydrate catabolic process is_a: GO:0044282 ! small molecule catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:35381 ! has primary input monosaccharide relationship: RO:0004009 CHEBI:35381 ! has primary input monosaccharide [Term] id: GO:0046394 name: carboxylic acid biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups." [ISBN:0198506732] synonym: "carboxylic acid anabolism" EXACT [] synonym: "carboxylic acid biosynthesis" EXACT [] synonym: "carboxylic acid formation" EXACT [] synonym: "carboxylic acid synthesis" EXACT [] is_a: GO:0016053 ! organic acid biosynthetic process is_a: GO:0019752 ! carboxylic acid metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:29067 ! has primary output carboxylic acid anion relationship: RO:0004008 CHEBI:29067 ! has primary output carboxylic acid anion [Term] id: GO:0046395 name: carboxylic acid catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups." [ISBN:0198506732] synonym: "carboxylic acid breakdown" EXACT [] synonym: "carboxylic acid catabolism" EXACT [] synonym: "carboxylic acid degradation" EXACT [] is_a: GO:0016054 ! organic acid catabolic process is_a: GO:0019752 ! carboxylic acid metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:29067 ! has primary input carboxylic acid anion relationship: RO:0004009 CHEBI:29067 ! has primary input carboxylic acid anion [Term] id: GO:0046483 name: heterocycle metabolic process namespace: biological_process def: "The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings)." [ISBN:0198506732] synonym: "heterocycle metabolism" EXACT [] is_a: GO:0044237 ! cellular metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:5686 ! has primary input or output heterocyclic compound relationship: RO:0004007 CHEBI:5686 ! has primary input or output heterocyclic compound [Term] id: GO:0046530 name: photoreceptor cell differentiation namespace: biological_process def: "The specialization of organization of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light. An example of this process is found in Drosophila melanogaster." [GOC:ai, ISBN:0198506732] is_a: GO:0030182 ! neuron differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000210 ! results in acquisition of features of photoreceptor cell relationship: RO:0002315 CL:0000210 ! results in acquisition of features of photoreceptor cell [Term] id: GO:0046532 name: regulation of photoreceptor cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster." [GOC:go_curators] synonym: "regulation of photoreceptor differentiation" EXACT [] is_a: GO:0045664 ! regulation of neuron differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0046530 ! regulates (processual) photoreceptor cell differentiation relationship: RO:0002211 GO:0046530 ! regulates (processual) photoreceptor cell differentiation [Term] id: GO:0046533 name: negative regulation of photoreceptor cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster." [GOC:go_curators] synonym: "down regulation of photoreceptor cell differentiation" EXACT [] synonym: "down regulation of photoreceptor differentiation" EXACT [] synonym: "down-regulation of photoreceptor cell differentiation" EXACT [] synonym: "down-regulation of photoreceptor differentiation" EXACT [] synonym: "downregulation of photoreceptor cell differentiation" EXACT [] synonym: "downregulation of photoreceptor differentiation" EXACT [] synonym: "negative regulation of photoreceptor differentiation" EXACT [] is_a: GO:0045665 ! negative regulation of neuron differentiation is_a: GO:0046532 ! regulation of photoreceptor cell differentiation is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0046530 ! negatively regulates photoreceptor cell differentiation relationship: RO:0002212 GO:0046530 ! negatively regulates photoreceptor cell differentiation [Term] id: GO:0046534 name: positive regulation of photoreceptor cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster." [GOC:go_curators] synonym: "positive regulation of photoreceptor differentiation" EXACT [] synonym: "up regulation of photoreceptor cell differentiation" EXACT [] synonym: "up regulation of photoreceptor differentiation" EXACT [] synonym: "up-regulation of photoreceptor cell differentiation" EXACT [] synonym: "up-regulation of photoreceptor differentiation" EXACT [] synonym: "upregulation of photoreceptor cell differentiation" EXACT [] synonym: "upregulation of photoreceptor differentiation" EXACT [] is_a: GO:0045666 ! positive regulation of neuron differentiation is_a: GO:0046532 ! regulation of photoreceptor cell differentiation is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0046530 ! positively regulates photoreceptor cell differentiation relationship: RO:0002213 GO:0046530 ! positively regulates photoreceptor cell differentiation [Term] id: GO:0046545 name: development of primary female sexual characteristics namespace: biological_process def: "The process whose specific outcome is the progression of the primary female sexual characteristics over time, from their formation to the mature structure. The primary female sexual characteristics are the ovaries, and they develop in response to sex hormone secretion." [GOC:ai] is_a: GO:0045137 ! development of primary sexual characteristics relationship: BFO:0000050 GO:0046660 ! part of female sex differentiation [Term] id: GO:0046546 name: development of primary male sexual characteristics namespace: biological_process def: "The process whose specific outcome is the progression of the primary male sexual characteristics over time, from their formation to the mature structures. The primary male sexual characteristics are the testes, and they develop in response to sex hormone secretion." [GOC:ai] is_a: GO:0045137 ! development of primary sexual characteristics relationship: BFO:0000050 GO:0046661 ! part of male sex differentiation [Term] id: GO:0046548 name: retinal rod cell development namespace: biological_process def: "Development of a rod cell, one of the sensory cells in the eye that reacts to the presence of light. Rod cells contain the photopigment rhodopsin or porphyropsin and are responsible for vision in dim light." [ISBN:0198506732] is_a: GO:0042462 ! eye photoreceptor cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000604 ! results in development of retinal rod cell relationship: BFO:0000050 GO:0060221 ! part of retinal rod cell differentiation relationship: RO:0002296 CL:0000604 ! results in development of retinal rod cell [Term] id: GO:0046549 name: retinal cone cell development namespace: biological_process def: "Development of a cone cell, one of the sensory cells in the eye that reacts to the presence of light. Cone cells contain the photopigment iodopsin or cyanopsin and are responsible for photopic (daylight) vision." [ISBN:0198506732] is_a: GO:0042462 ! eye photoreceptor cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000573 ! results in development of retinal cone cell relationship: BFO:0000050 GO:0042670 ! part of retinal cone cell differentiation relationship: RO:0002296 CL:0000573 ! results in development of retinal cone cell [Term] id: GO:0046620 name: regulation of organ growth namespace: biological_process def: "Any process that modulates the frequency, rate or extent of growth of an organ of an organism." [GOC:bf, GOC:tb] is_a: GO:0048638 ! regulation of developmental growth is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0035265 ! regulates (processual) organ growth relationship: RO:0002211 GO:0035265 ! regulates (processual) organ growth [Term] id: GO:0046621 name: negative regulation of organ growth namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism." [GOC:bf, GOC:tb] is_a: GO:0046620 ! regulation of organ growth is_a: GO:0048640 ! negative regulation of developmental growth is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0035265 ! negatively regulates organ growth relationship: RO:0002212 GO:0035265 ! negatively regulates organ growth [Term] id: GO:0046622 name: positive regulation of organ growth namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of growth of an organ of an organism." [GOC:bf, GOC:tb] is_a: GO:0046620 ! regulation of organ growth is_a: GO:0048639 ! positive regulation of developmental growth is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0035265 ! positively regulates organ growth relationship: RO:0002213 GO:0035265 ! positively regulates organ growth [Term] id: GO:0046649 name: lymphocyte activation namespace: biological_process def: "A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor." [GOC:mgi_curators, ISBN:0781735149] is_a: GO:0045321 ! leukocyte activation intersection_of: GO:0001775 ! cell activation intersection_of: RO:0004009 CL:0000542 ! has primary input lymphocyte relationship: RO:0004009 CL:0000542 ! has primary input lymphocyte [Term] id: GO:0046651 name: lymphocyte proliferation namespace: biological_process def: "The expansion of a lymphocyte population by cell division." [GOC:ai] is_a: GO:0032943 ! mononuclear cell proliferation is_a: GO:0046649 ! lymphocyte activation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000542 ! acts on population of lymphocyte relationship: RO:0012003 CL:0000542 ! acts on population of lymphocyte [Term] id: GO:0046660 name: female sex differentiation namespace: biological_process def: "The establishment of the sex of a female organism by physical differentiation." [GOC:bf] is_a: GO:0007548 ! sex differentiation relationship: BFO:0000050 GO:0007275 ! part of multicellular organism development [Term] id: GO:0046661 name: male sex differentiation namespace: biological_process def: "The establishment of the sex of a male organism by physical differentiation." [GOC:bf] is_a: GO:0007548 ! sex differentiation relationship: BFO:0000050 GO:0007275 ! part of multicellular organism development [Term] id: GO:0046666 name: retinal cell programmed cell death namespace: biological_process def: "Programmed cell death that occurs in the developing retina." [GOC:bf] synonym: "programmed cell death, retina cells" EXACT [] synonym: "programmed cell death, retinal cells" EXACT [] synonym: "retina cell programmed cell death" EXACT [] synonym: "retina programmed cell death" EXACT [] synonym: "retinal programmed cell death" EXACT [] is_a: GO:0010623 ! programmed cell death involved in cell development relationship: BFO:0000050 GO:0048592 ! part of eye morphogenesis [Term] id: GO:0046667 name: compound eye retinal cell programmed cell death namespace: biological_process def: "Programmed cell death that occurs in the retina to remove excess cells between ommatidia, thus resulting in a hexagonal lattice, precise with respect to cell number and position surrounding each ommatidium." [PMID:12006672] is_a: GO:0046666 ! retinal cell programmed cell death intersection_of: GO:0046666 ! retinal cell programmed cell death intersection_of: RO:0002299 UBERON:0000018 ! results in maturation of compound eye relationship: BFO:0000050 GO:0001745 ! part of compound eye morphogenesis relationship: RO:0002299 UBERON:0000018 ! results in maturation of compound eye [Term] id: GO:0046668 name: regulation of retinal cell programmed cell death namespace: biological_process def: "Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the retina." [GOC:ai, GOC:tb] synonym: "regulation of retinal programmed cell death" EXACT [GOC:tb] is_a: GO:0043067 ! regulation of programmed cell death is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0046666 ! regulates (processual) retinal cell programmed cell death relationship: RO:0002211 GO:0046666 ! regulates (processual) retinal cell programmed cell death [Term] id: GO:0046669 name: regulation of compound eye retinal cell programmed cell death namespace: biological_process def: "Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the compound eye retina." [GOC:ai] is_a: GO:0046668 ! regulation of retinal cell programmed cell death intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0046667 ! regulates (processual) compound eye retinal cell programmed cell death relationship: RO:0002211 GO:0046667 ! regulates (processual) compound eye retinal cell programmed cell death [Term] id: GO:0046670 name: positive regulation of retinal cell programmed cell death namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the retina." [GOC:ai, GOC:tb] synonym: "positive regulation of retinal programmed cell death" EXACT [GOC:tb] synonym: "up regulation of retinal programmed cell death" EXACT [] synonym: "up-regulation of retinal programmed cell death" EXACT [] synonym: "upregulation of retinal programmed cell death" EXACT [] is_a: GO:0043068 ! positive regulation of programmed cell death is_a: GO:0046668 ! regulation of retinal cell programmed cell death is_a: GO:0051094 ! positive regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0046666 ! positively regulates retinal cell programmed cell death relationship: RO:0002213 GO:0046666 ! positively regulates retinal cell programmed cell death [Term] id: GO:0046671 name: negative regulation of retinal cell programmed cell death namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the retina." [GOC:ai, GOC:tb] synonym: "down regulation of retinal programmed cell death" EXACT [] synonym: "down-regulation of retinal programmed cell death" EXACT [] synonym: "downregulation of retinal programmed cell death" EXACT [] synonym: "negative regulation of retinal programmed cell death" EXACT [GOC:tb] is_a: GO:0043069 ! negative regulation of programmed cell death is_a: GO:0046668 ! regulation of retinal cell programmed cell death is_a: GO:0051093 ! negative regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0046666 ! negatively regulates retinal cell programmed cell death relationship: RO:0002212 GO:0046666 ! negatively regulates retinal cell programmed cell death [Term] id: GO:0046672 name: positive regulation of compound eye retinal cell programmed cell death namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the compound eye retina." [GOC:ai] is_a: GO:0046669 ! regulation of compound eye retinal cell programmed cell death is_a: GO:0046670 ! positive regulation of retinal cell programmed cell death intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0046667 ! positively regulates compound eye retinal cell programmed cell death relationship: RO:0002213 GO:0046667 ! positively regulates compound eye retinal cell programmed cell death [Term] id: GO:0046673 name: negative regulation of compound eye retinal cell programmed cell death namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the compound eye retina." [GOC:ai] is_a: GO:0046669 ! regulation of compound eye retinal cell programmed cell death is_a: GO:0046671 ! negative regulation of retinal cell programmed cell death intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0046667 ! negatively regulates compound eye retinal cell programmed cell death relationship: RO:0002212 GO:0046667 ! negatively regulates compound eye retinal cell programmed cell death [Term] id: GO:0046676 name: negative regulation of insulin secretion namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of insulin." [GOC:ai] synonym: "down regulation of insulin secretion" EXACT [] synonym: "down-regulation of insulin secretion" EXACT [] synonym: "downregulation of insulin secretion" EXACT [] is_a: GO:0050709 ! negative regulation of protein secretion is_a: GO:0050796 ! regulation of insulin secretion is_a: GO:0090278 ! negative regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030073 ! negatively regulates insulin secretion relationship: RO:0002212 GO:0030073 ! negatively regulates insulin secretion [Term] id: GO:0046681 name: response to carbamate namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbamate stimulus. Carbamates are a group of insecticides and parasiticides that act by inhibiting cholinesterase." [ISBN:0721662544] is_a: GO:0010243 ! response to organonitrogen compound is_a: GO:0017085 ! response to insecticide is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:13941 ! has primary input carbamate relationship: RO:0004009 CHEBI:13941 ! has primary input carbamate [Term] id: GO:0046700 name: heterocycle catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings)." [GOC:ai] synonym: "heterocycle breakdown" EXACT [] synonym: "heterocycle catabolism" EXACT [] synonym: "heterocycle degradation" EXACT [] is_a: GO:0044248 ! cellular catabolic process is_a: GO:0046483 ! heterocycle metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:5686 ! has primary input heterocyclic compound relationship: RO:0004009 CHEBI:5686 ! has primary input heterocyclic compound [Term] id: GO:0046716 name: muscle cell cellular homeostasis namespace: biological_process def: "The cellular homeostatic process that preserves a muscle cell in a stable functional or structural state." [GOC:mah, PMID:3091429, PMID:7781901] is_a: GO:0019725 ! cellular homeostasis intersection_of: GO:0019725 ! cellular homeostasis intersection_of: BFO:0000066 CL:0000187 ! occurs in muscle cell relationship: BFO:0000066 CL:0000187 ! occurs in muscle cell [Term] id: GO:0046717 name: acid secretion namespace: biological_process def: "The controlled release of acid by a cell or a tissue." [GOC:ai] is_a: GO:0046903 ! secretion [Term] id: GO:0046785 name: microtubule polymerization namespace: biological_process def: "The addition of tubulin heterodimers to one or both ends of a microtubule." [GOC:ai, GOC:go_curators] synonym: "microtubule assembly" EXACT [] is_a: GO:0031109 ! microtubule polymerization or depolymerization is_a: GO:0051258 ! protein polymerization is_a: GO:0097435 ! supramolecular fiber organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0005874 ! results in assembly of microtubule relationship: RO:0002224 GO:0007020 ! starts with microtubule nucleation relationship: RO:0002588 GO:0005874 ! results in assembly of microtubule [Term] id: GO:0046873 name: metal ion transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of metal ions from one side of a membrane to the other." [GOC:ai] is_a: GO:0008324 ! monoatomic cation transmembrane transporter activity is_a: GO:0022890 ! inorganic cation transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:25213 ! has primary input metal cation relationship: BFO:0000050 GO:0030001 ! part of metal ion transport relationship: RO:0004009 CHEBI:25213 ! has primary input metal cation [Term] id: GO:0046879 name: hormone secretion namespace: biological_process def: "The regulated release of hormones, substances with a specific regulatory effect on a particular organ or group of cells." [ISBN:0198506732] is_a: GO:0009914 ! hormone transport is_a: GO:0023061 ! signal release [Term] id: GO:0046883 name: regulation of hormone secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of a hormone from a cell." [GOC:ai] is_a: GO:0010646 ! regulation of cell communication is_a: GO:0010817 ! regulation of hormone levels is_a: GO:0023051 ! regulation of signaling is_a: GO:1903530 ! regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0046879 ! regulates (processual) hormone secretion relationship: RO:0002211 GO:0046879 ! regulates (processual) hormone secretion [Term] id: GO:0046887 name: positive regulation of hormone secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of a hormone from a cell." [GOC:ai] synonym: "up regulation of hormone secretion" EXACT [] synonym: "up-regulation of hormone secretion" EXACT [] synonym: "upregulation of hormone secretion" EXACT [] is_a: GO:0010647 ! positive regulation of cell communication is_a: GO:0023056 ! positive regulation of signaling is_a: GO:0046883 ! regulation of hormone secretion is_a: GO:1903532 ! positive regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0046879 ! positively regulates hormone secretion relationship: RO:0002213 GO:0046879 ! positively regulates hormone secretion [Term] id: GO:0046888 name: negative regulation of hormone secretion namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a hormone from a cell." [GOC:ai] synonym: "down regulation of hormone secretion" EXACT [] synonym: "down-regulation of hormone secretion" EXACT [] synonym: "downregulation of hormone secretion" EXACT [] is_a: GO:0010648 ! negative regulation of cell communication is_a: GO:0023057 ! negative regulation of signaling is_a: GO:0046883 ! regulation of hormone secretion is_a: GO:1903531 ! negative regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0046879 ! negatively regulates hormone secretion relationship: RO:0002212 GO:0046879 ! negatively regulates hormone secretion [Term] id: GO:0046889 name: positive regulation of lipid biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids." [GOC:ai] synonym: "positive regulation of lipid anabolism" EXACT [] synonym: "positive regulation of lipid biosynthesis" EXACT [] synonym: "positive regulation of lipid formation" EXACT [] synonym: "positive regulation of lipid synthesis" EXACT [] synonym: "positive regulation of lipogenesis" EXACT [GOC:sl] synonym: "up regulation of lipid biosynthetic process" EXACT [] synonym: "up-regulation of lipid biosynthetic process" EXACT [] synonym: "upregulation of lipid biosynthetic process" EXACT [] is_a: GO:0009891 ! positive regulation of biosynthetic process is_a: GO:0045834 ! positive regulation of lipid metabolic process is_a: GO:0046890 ! regulation of lipid biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0008610 ! positively regulates lipid biosynthetic process relationship: RO:0002213 GO:0008610 ! positively regulates lipid biosynthetic process [Term] id: GO:0046890 name: regulation of lipid biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids." [GOC:ai] synonym: "regulation of lipid anabolism" EXACT [] synonym: "regulation of lipid biosynthesis" EXACT [] synonym: "regulation of lipid formation" EXACT [] synonym: "regulation of lipid synthesis" EXACT [] synonym: "regulation of lipogenesis" EXACT [GOC:sl] is_a: GO:0009889 ! regulation of biosynthetic process is_a: GO:0019216 ! regulation of lipid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0008610 ! regulates (processual) lipid biosynthetic process relationship: RO:0002211 GO:0008610 ! regulates (processual) lipid biosynthetic process [Term] id: GO:0046903 name: secretion namespace: biological_process def: "The controlled release of a substance by a cell or a tissue." [GOC:ai] is_a: GO:0006810 ! transport [Term] id: GO:0046907 name: intracellular transport namespace: biological_process def: "The directed movement of substances within a cell." [GOC:ai] is_a: GO:0006810 ! transport is_a: GO:0051641 ! cellular localization is_a: GO:0051649 ! establishment of localization in cell intersection_of: GO:0006810 ! transport intersection_of: BFO:0000066 GO:0005622 ! occurs in intracellular anatomical structure relationship: BFO:0000066 GO:0005622 ! occurs in intracellular anatomical structure creation_date: 2013-12-18T14:04:50Z [Term] id: GO:0046928 name: regulation of neurotransmitter secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell." [GOC:ai] is_a: GO:0050804 ! modulation of chemical synaptic transmission is_a: GO:0051588 ! regulation of neurotransmitter transport is_a: GO:1903530 ! regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007269 ! regulates (processual) neurotransmitter secretion relationship: RO:0002211 GO:0007269 ! regulates (processual) neurotransmitter secretion [Term] id: GO:0046929 name: negative regulation of neurotransmitter secretion namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a neurotransmitter." [GOC:ai] synonym: "down regulation of neurotransmitter secretion" EXACT [] synonym: "down-regulation of neurotransmitter secretion" EXACT [] synonym: "downregulation of neurotransmitter secretion" EXACT [] is_a: GO:0046928 ! regulation of neurotransmitter secretion is_a: GO:0051589 ! negative regulation of neurotransmitter transport is_a: GO:1903531 ! negative regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007269 ! negatively regulates neurotransmitter secretion relationship: RO:0002212 GO:0007269 ! negatively regulates neurotransmitter secretion [Term] id: GO:0046942 name: carboxylic acid transport namespace: biological_process def: "The directed movement of carboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-)." [GOC:ai] is_a: GO:0015711 ! organic anion transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:29067 ! has primary input carboxylic acid anion relationship: RO:0004009 CHEBI:29067 ! has primary input carboxylic acid anion [Term] id: GO:0046943 name: carboxylic acid transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of carboxylic acids from one side of a membrane to the other. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-)." [GOC:ai] xref: Reactome:R-HSA-390347 "Exchange of isocitrate and 2-oxoglutarate across the peroxisomal membrane" is_a: GO:0008514 ! organic anion transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:29067 ! has primary input carboxylic acid anion relationship: BFO:0000050 GO:1905039 ! part of carboxylic acid transmembrane transport relationship: RO:0004009 CHEBI:29067 ! has primary input carboxylic acid anion [Term] id: GO:0047496 name: vesicle transport along microtubule namespace: biological_process def: "The directed movement of a vesicle along a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination." [GOC:ecd, GOC:rl] synonym: "microtubule-based vesicle localization" EXACT [GOC:rl] is_a: GO:0072384 ! organelle transport along microtubule is_a: GO:0099518 ! vesicle cytoskeletal trafficking intersection_of: GO:0006810 ! transport intersection_of: RO:0002341 GO:0005874 ! results in transport along microtubule intersection_of: RO:0004009 GO:0031982 ! has primary input vesicle [Term] id: GO:0048048 name: embryonic eye morphogenesis namespace: biological_process def: "The process occurring in the embryo by which the anatomical structures of the post-embryonic eye are generated and organized." [GOC:jid] is_a: GO:0048562 ! embryonic organ morphogenesis is_a: GO:0048592 ! eye morphogenesis [Term] id: GO:0048066 name: developmental pigmentation namespace: biological_process def: "The developmental process that results in the deposition of coloring matter in an organism, tissue or cell." [ISBN:0582227089] is_a: GO:0043473 ! pigmentation [Term] id: GO:0048070 name: regulation of developmental pigmentation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism." [GOC:dph, GOC:jid, GOC:tb] synonym: "regulation of pigmentation during development" EXACT [GOC:dph, GOC:tb] is_a: GO:0120305 ! regulation of pigmentation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048066 ! regulates (processual) developmental pigmentation relationship: RO:0002211 GO:0048066 ! regulates (processual) developmental pigmentation [Term] id: GO:0048086 name: negative regulation of developmental pigmentation namespace: biological_process def: "Any process that decreases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism." [GOC:dph, GOC:jid, GOC:tb] synonym: "down regulation of developmental pigmentation" EXACT [GOC:dph, GOC:tb] synonym: "down-regulation of developmental pigmentation" EXACT [GOC:dph, GOC:tb] synonym: "downregulation of developmental pigmentation" EXACT [GOC:dph, GOC:tb] is_a: GO:0048070 ! regulation of developmental pigmentation is_a: GO:0048519 ! negative regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048066 ! negatively regulates developmental pigmentation relationship: RO:0002212 GO:0048066 ! negatively regulates developmental pigmentation [Term] id: GO:0048087 name: positive regulation of developmental pigmentation namespace: biological_process def: "Any process that increases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism." [GOC:dph, GOC:jid, GOC:tb] synonym: "up regulation of developmental pigmentation" EXACT [GOC:dph] synonym: "up-regulation of developmental pigmentation" EXACT [GOC:dph, GOC:tb] synonym: "upregulation of developmental pigmentation" EXACT [GOC:dph, GOC:tb] is_a: GO:0048070 ! regulation of developmental pigmentation is_a: GO:0048518 ! positive regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0048066 ! positively regulates developmental pigmentation relationship: RO:0002213 GO:0048066 ! positively regulates developmental pigmentation [Term] id: GO:0048103 name: somatic stem cell division namespace: biological_process def: "The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line." [GOC:jid, ISBN:0582227089] synonym: "somatic stem cell renewal" EXACT [] is_a: GO:0017145 ! stem cell division intersection_of: GO:0051301 ! cell division intersection_of: RO:0004009 CL:0000723 ! has primary input somatic stem cell relationship: RO:0004009 CL:0000723 ! has primary input somatic stem cell [Term] id: GO:0048132 name: female germ-line stem cell asymmetric division namespace: biological_process def: "The self-renewing division of a germline stem cell in the female gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the female gametes." [GOC:jid, GOC:mtg_sensu] synonym: "female germ-line stem cell renewal" EXACT [] is_a: GO:0098728 ! germline stem cell asymmetric division intersection_of: GO:0008356 ! asymmetric cell division intersection_of: RO:0004009 CL:0000022 ! has primary input female germ line stem cell relationship: BFO:0000050 GO:0048477 ! part of oogenesis relationship: RO:0002160 NCBITaxon:6656 ! only in taxon Arthropoda relationship: RO:0002162 NCBITaxon:6656 {all_only="true"} ! in taxon Arthropoda relationship: RO:0004009 CL:0000022 ! has primary input female germ line stem cell [Term] id: GO:0048137 name: spermatocyte division namespace: biological_process def: "The meiotic divisions undergone by the primary and secondary spermatocytes to produce haploid spermatids." [GOC:jid, GOC:pr, ISBN:0879694238] synonym: "spermatocyte cell division" EXACT [] is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0051301 ! cell division intersection_of: GO:0051301 ! cell division intersection_of: RO:0004009 CL:0000017 ! has primary input spermatocyte relationship: BFO:0000050 GO:0007283 ! part of spermatogenesis relationship: RO:0004009 CL:0000017 ! has primary input spermatocyte [Term] id: GO:0048144 name: fibroblast proliferation namespace: biological_process def: "The multiplication or reproduction of fibroblast cells, resulting in the expansion of the fibroblast population." [GOC:jid] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000057 ! acts on population of fibroblast relationship: RO:0012003 CL:0000057 ! acts on population of fibroblast [Term] id: GO:0048145 name: regulation of fibroblast proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of multiplication or reproduction of fibroblast cells." [GOC:jid] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048144 ! regulates (processual) fibroblast proliferation relationship: RO:0002211 GO:0048144 ! regulates (processual) fibroblast proliferation [Term] id: GO:0048146 name: positive regulation of fibroblast proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells." [GOC:jid] synonym: "up regulation of fibroblast proliferation" EXACT [] synonym: "up-regulation of fibroblast proliferation" EXACT [] synonym: "upregulation of fibroblast proliferation" EXACT [] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0048145 ! regulation of fibroblast proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0048144 ! positively regulates fibroblast proliferation relationship: RO:0002213 GO:0048144 ! positively regulates fibroblast proliferation [Term] id: GO:0048147 name: negative regulation of fibroblast proliferation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells." [GOC:jid] synonym: "down regulation of fibroblast proliferation" EXACT [] synonym: "down-regulation of fibroblast proliferation" EXACT [] synonym: "downregulation of fibroblast proliferation" EXACT [] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0048145 ! regulation of fibroblast proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048144 ! negatively regulates fibroblast proliferation relationship: RO:0002212 GO:0048144 ! negatively regulates fibroblast proliferation [Term] id: GO:0048193 name: Golgi vesicle transport namespace: biological_process def: "The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles." [GOC:jid, ISBN:0716731363, PMID:10219233] is_a: GO:0016192 ! vesicle-mediated transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002344 GO:0005798 ! results in transport to from or in Golgi-associated vesicle relationship: RO:0002344 GO:0005798 ! results in transport to from or in Golgi-associated vesicle [Term] id: GO:0048194 name: Golgi vesicle budding namespace: biological_process def: "The evagination of the Golgi membrane, resulting in formation of a vesicle." [GOC:jid, ISBN:0716731363, PMID:10219233] synonym: "Golgi-derived vesicle budding" EXACT [] is_a: GO:0006900 ! vesicle budding from membrane intersection_of: GO:0006900 ! vesicle budding from membrane intersection_of: BFO:0000066 GO:0000139 ! occurs in Golgi membrane intersection_of: RO:0004008 GO:0005798 ! has primary output Golgi-associated vesicle relationship: BFO:0000050 GO:0048193 ! part of Golgi vesicle transport relationship: BFO:0000066 GO:0000139 ! occurs in Golgi membrane relationship: RO:0004008 GO:0005798 ! has primary output Golgi-associated vesicle [Term] id: GO:0048199 name: vesicle targeting, to, from or within Golgi namespace: biological_process def: "The process in which vesicles are directed to specific destination membranes during transport to, from or within the Golgi apparatus; mediated by the addition of specific coat proteins, including COPI and COPII proteins and clathrin, to the membrane during vesicle formation." [GOC:jid, GOC:mah, ISBN:0716731363, PMID:10219233] synonym: "Golgi vesicle targeting" EXACT [] is_a: GO:0006903 ! vesicle targeting intersection_of: GO:0006903 ! vesicle targeting intersection_of: RO:0002344 GO:0005794 ! results in transport to from or in Golgi apparatus intersection_of: RO:0004009 GO:0005798 ! has primary input Golgi-associated vesicle relationship: BFO:0000050 GO:0048193 ! part of Golgi vesicle transport relationship: RO:0002344 GO:0005794 ! results in transport to from or in Golgi apparatus relationship: RO:0004009 GO:0005798 ! has primary input Golgi-associated vesicle [Term] id: GO:0048209 name: regulation of vesicle targeting, to, from or within Golgi namespace: biological_process def: "Any process that modulates the frequency, rate, or destination of vesicle-mediated transport to, from or within the Golgi apparatus." [GOC:jid, GOC:mah, ISBN:0716731363, PMID:10219233] synonym: "regulation of Golgi vesicle targeting" EXACT [] is_a: GO:0060341 ! regulation of cellular localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048199 ! regulates (processual) vesicle targeting, to, from or within Golgi relationship: RO:0002211 GO:0048199 ! regulates (processual) vesicle targeting, to, from or within Golgi [Term] id: GO:0048232 name: male gamete generation namespace: biological_process def: "Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction." [GOC:dph, GOC:jid] is_a: GO:0007276 ! gamete generation [Term] id: GO:0048240 name: sperm capacitation namespace: biological_process def: "A process required for sperm to reach fertilization competence. Sperm undergo an incompletely understood series of morphological and molecular maturational processes, termed capacitation, involving, among other processes, protein tyrosine phosphorylation and increased intracellular calcium." [GOC:jid, ISBN:978-3-642-58301-8, PMID:11820818] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0048469 ! cell maturation relationship: BFO:0000050 GO:0007286 ! part of spermatid development [Term] id: GO:0048243 name: norepinephrine secretion namespace: biological_process def: "The regulated release of norepinephrine by a cell. Norepinephrine is a catecholamine and it acts as a hormone and as a neurotransmitter of most of the sympathetic nervous system." [GOC:ef, GOC:jid] synonym: "noradrenaline secretion" EXACT [] is_a: GO:0015874 ! norepinephrine transport is_a: GO:0023061 ! signal release is_a: GO:0050432 ! catecholamine secretion intersection_of: GO:0046903 ! secretion intersection_of: RO:0004009 CHEBI:72587 ! has primary input (R)-noradrenaline(1+) [Term] id: GO:0048251 name: elastic fiber assembly namespace: biological_process def: "Assembly of the extracellular matrix fibers that enables the matrix to recoil after transient stretching." [GOC:jid, PMID:10841810, PMID:12615674] synonym: "elastic fibre assembly" EXACT [] synonym: "elastin fiber assembly" EXACT [GOC:BHF] synonym: "elastin fibre assembly" EXACT [GOC:BHF] is_a: GO:0085029 ! extracellular matrix assembly is_a: GO:0097435 ! supramolecular fiber organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0071953 ! results in assembly of elastic fiber relationship: RO:0002588 GO:0071953 ! results in assembly of elastic fiber [Term] id: GO:0048280 name: vesicle fusion with Golgi apparatus namespace: biological_process def: "The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi." [GOC:jid] is_a: GO:0006906 ! vesicle fusion is_a: GO:0007030 ! Golgi organization intersection_of: GO:0009987 ! cellular process intersection_of: RO:0012008 GO:0005794 ! results in fusion of Golgi apparatus intersection_of: RO:0012008 GO:0031982 ! results in fusion of vesicle relationship: BFO:0000050 GO:0048193 ! part of Golgi vesicle transport relationship: RO:0012008 GO:0005794 ! results in fusion of Golgi apparatus relationship: RO:0012008 GO:0031982 ! results in fusion of vesicle [Term] id: GO:0048284 name: organelle fusion namespace: biological_process def: "The creation of a single organelle from two or more organelles." [GOC:jid] is_a: GO:0006996 ! organelle organization intersection_of: GO:0009987 ! cellular process intersection_of: RO:0012008 GO:0043226 ! results in fusion of organelle relationship: RO:0012008 GO:0043226 ! results in fusion of organelle [Term] id: GO:0048285 name: organelle fission namespace: biological_process def: "The creation of two or more organelles by division of one organelle." [GOC:jid] is_a: GO:0006996 ! organelle organization intersection_of: GO:0009987 ! cellular process intersection_of: GOREL:0002004 GO:0043226 ! results in fission of organelle relationship: GOREL:0002004 GO:0043226 ! results in fission of organelle [Term] id: GO:0048288 name: nuclear membrane fusion involved in karyogamy namespace: biological_process def: "The joining of 2 or more lipid bilayer membranes that surround the nucleus during the creation of a single nucleus from multiple nuclei." [GOC:jid] is_a: GO:0000740 ! nuclear membrane fusion intersection_of: GO:0000740 ! nuclear membrane fusion intersection_of: BFO:0000050 GO:0000741 ! part of karyogamy relationship: BFO:0000050 GO:0000741 ! part of karyogamy [Term] id: GO:0048308 name: organelle inheritance namespace: biological_process def: "The partitioning of organelles between daughter cells at cell division." [GOC:jid] is_a: GO:0006996 ! organelle organization [Term] id: GO:0048313 name: Golgi inheritance namespace: biological_process def: "The partitioning of Golgi apparatus between daughter cells at cell division." [GOC:jid, PMID:12851069] synonym: "Golgi apparatus inheritance" EXACT [] synonym: "Golgi division" EXACT [GOC:ascb_2009, GOC:dph, GOC:tb] synonym: "Golgi partitioning" EXACT [] is_a: GO:0007030 ! Golgi organization is_a: GO:0048308 ! organelle inheritance intersection_of: GO:0048308 ! organelle inheritance intersection_of: GOREL:0002003 GO:0005794 ! results in distribution of Golgi apparatus relationship: GOREL:0002003 GO:0005794 ! results in distribution of Golgi apparatus [Term] id: GO:0048318 name: axial mesoderm development namespace: biological_process def: "The process whose specific outcome is the progression of the axial mesoderm over time, from its formation to the mature structure. The axial mesoderm includes the prechordal mesoderm and the chordamesoderm. It gives rise to the prechordal plate and to the notochord." [GOC:dgh] is_a: GO:0007498 ! mesoderm development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003068 ! results in development of axial mesoderm relationship: RO:0002296 UBERON:0003068 ! results in development of axial mesoderm [Term] id: GO:0048319 name: axial mesoderm morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the axial mesoderm are generated and organized." [GOC:go_curators] is_a: GO:0048332 ! mesoderm morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003068 ! results in morphogenesis of axial mesoderm relationship: BFO:0000050 GO:0048318 ! part of axial mesoderm development relationship: RO:0002298 UBERON:0003068 ! results in morphogenesis of axial mesoderm [Term] id: GO:0048320 name: axial mesoderm formation namespace: biological_process def: "The process that gives rise to the axial mesoderm. This process pertains to the initial formation of the structure from unspecified parts." [GOC:dgh] is_a: GO:0001707 ! mesoderm formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0003068 ! results in formation of anatomical entity axial mesoderm relationship: BFO:0000050 GO:0048319 ! part of axial mesoderm morphogenesis relationship: RO:0002297 UBERON:0003068 ! results in formation of anatomical entity axial mesoderm [Term] id: GO:0048332 name: mesoderm morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the mesoderm are generated and organized." [GOC:go_curators] is_a: GO:0048729 ! tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000926 ! results in morphogenesis of mesoderm relationship: BFO:0000050 GO:0007498 ! part of mesoderm development relationship: RO:0002298 UBERON:0000926 ! results in morphogenesis of mesoderm [Term] id: GO:0048333 name: mesodermal cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized features of a mesoderm cell." [GOC:dgh] synonym: "mesoderm cell differentiation" EXACT [] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000222 ! results in acquisition of features of mesodermal cell relationship: BFO:0000050 GO:0001707 ! part of mesoderm formation relationship: RO:0002315 CL:0000222 ! results in acquisition of features of mesodermal cell [Term] id: GO:0048339 name: paraxial mesoderm development namespace: biological_process def: "The process whose specific outcome is the progression of the paraxial mesoderm over time, from its formation to the mature structure. The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube." [GOC:dgh] is_a: GO:0007498 ! mesoderm development is_a: GO:0060485 ! mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003077 ! results in development of paraxial mesoderm relationship: RO:0002296 UBERON:0003077 ! results in development of paraxial mesoderm [Term] id: GO:0048340 name: paraxial mesoderm morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the paraxial mesoderm are generated and organized." [GOC:go_curators] is_a: GO:0048332 ! mesoderm morphogenesis is_a: GO:0072132 ! mesenchyme morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003077 ! results in morphogenesis of paraxial mesoderm relationship: BFO:0000050 GO:0048339 ! part of paraxial mesoderm development relationship: RO:0002298 UBERON:0003077 ! results in morphogenesis of paraxial mesoderm [Term] id: GO:0048341 name: paraxial mesoderm formation namespace: biological_process def: "The process that gives rise to the paraxial mesoderm. This process pertains to the initial formation of the structure from unspecified parts." [GOC:dgh] is_a: GO:0001707 ! mesoderm formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0003077 ! results in formation of anatomical entity paraxial mesoderm relationship: BFO:0000050 GO:0048340 ! part of paraxial mesoderm morphogenesis relationship: RO:0002297 UBERON:0003077 ! results in formation of anatomical entity paraxial mesoderm [Term] id: GO:0048368 name: lateral mesoderm development namespace: biological_process def: "The process whose specific outcome is the progression of the lateral mesoderm over time, from its formation to the mature structure." [GOC:go_curators] synonym: "lateral plate mesoderm development" EXACT [] is_a: GO:0007498 ! mesoderm development is_a: GO:0060485 ! mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003081 ! results in development of lateral plate mesoderm relationship: RO:0002296 UBERON:0003081 ! results in development of lateral plate mesoderm [Term] id: GO:0048369 name: lateral mesoderm morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the lateral mesoderm are generated and organized." [GOC:go_curators] synonym: "lateral plate mesoderm morphogenesis" EXACT [] is_a: GO:0048332 ! mesoderm morphogenesis is_a: GO:0072132 ! mesenchyme morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003081 ! results in morphogenesis of lateral plate mesoderm relationship: BFO:0000050 GO:0048368 ! part of lateral mesoderm development relationship: RO:0002298 UBERON:0003081 ! results in morphogenesis of lateral plate mesoderm [Term] id: GO:0048370 name: lateral mesoderm formation namespace: biological_process def: "The process that gives rise to the lateral mesoderm. This process pertains to the initial formation of the structure from unspecified parts." [GOC:jid] synonym: "lateral plate mesoderm biosynthesis" EXACT [] synonym: "lateral plate mesoderm formation" EXACT [] is_a: GO:0001707 ! mesoderm formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002298 UBERON:0003081 ! results in morphogenesis of lateral plate mesoderm relationship: BFO:0000050 GO:0048369 ! part of lateral mesoderm morphogenesis relationship: RO:0002298 UBERON:0003081 ! results in morphogenesis of lateral plate mesoderm [Term] id: GO:0048389 name: intermediate mesoderm development namespace: biological_process def: "The process whose specific outcome is the progression of the intermediate mesoderm over time, from its formation to the mature structure. The intermediate mesoderm is located between the lateral mesoderm and the paraxial mesoderm. It develops into the kidney and gonads." [GOC:dgh] is_a: GO:0007498 ! mesoderm development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003064 ! results in development of intermediate mesoderm relationship: RO:0002296 UBERON:0003064 ! results in development of intermediate mesoderm [Term] id: GO:0048390 name: intermediate mesoderm morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the intermediate mesoderm are generated and organized." [GOC:go_curators] is_a: GO:0048332 ! mesoderm morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003064 ! results in morphogenesis of intermediate mesoderm relationship: BFO:0000050 GO:0048389 ! part of intermediate mesoderm development relationship: RO:0002298 UBERON:0003064 ! results in morphogenesis of intermediate mesoderm [Term] id: GO:0048391 name: intermediate mesoderm formation namespace: biological_process def: "The process that gives rise to the intermediate mesoderm. This process pertains to the initial formation of the structure from unspecified parts." [GOC:dgh] is_a: GO:0001707 ! mesoderm formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0003064 ! results in formation of anatomical entity intermediate mesoderm relationship: BFO:0000050 GO:0048390 ! part of intermediate mesoderm morphogenesis relationship: RO:0002297 UBERON:0003064 ! results in formation of anatomical entity intermediate mesoderm [Term] id: GO:0048468 name: cell development namespace: biological_process def: "The cellular developmental process in which a specific cell progresses from an immature to a mature state. Cell development start once cell commitment has taken place." [GOC:go_curators] is_a: GO:0048856 ! anatomical structure development is_a: GO:0048869 ! cellular developmental process intersection_of: GO:0008150 ! biological_process intersection_of: RO:0002296 CL:0000000 ! results in development of cell relationship: BFO:0000050 GO:0030154 ! part of cell differentiation relationship: RO:0002296 CL:0000000 ! results in development of cell [Term] id: GO:0048469 name: cell maturation namespace: biological_process def: "The cellular developmental process, independent of morphogenetic (shape) change, that is required for a specific cell to attain its fully functional state." [GOC:go_curators] is_a: GO:0048869 ! cellular developmental process is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 CL:0000000 ! results in maturation of cell relationship: BFO:0000050 GO:0048468 ! part of cell development relationship: RO:0002299 CL:0000000 ! results in maturation of cell [Term] id: GO:0048477 name: oogenesis namespace: biological_process def: "The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster." [GOC:kmv, GOC:mtg_sensu, GOC:pr] xref: Wikipedia:Oogenesis is_a: GO:0007281 ! germ cell development is_a: GO:0007292 ! female gamete generation intersection_of: GO:0048468 ! cell development intersection_of: RO:0002296 CL:0000025 ! results in development of egg cell relationship: RO:0002160 NCBITaxon:33208 ! only in taxon Metazoa relationship: RO:0002162 NCBITaxon:33208 {all_only="true"} ! in taxon Metazoa relationship: RO:0002296 CL:0000025 ! results in development of egg cell [Term] id: GO:0048483 name: autonomic nervous system development namespace: biological_process def: "The process whose specific outcome is the progression of the autonomic nervous system over time, from its formation to the mature structure. The autonomic nervous system is composed of neurons that are not under conscious control, and is comprised of two antagonistic components, the sympathetic and parasympathetic nervous systems. The autonomic nervous system regulates key functions including the activity of the cardiac (heart) muscle, smooth muscles (e.g. of the gut), and glands." [FMA:9905, GOC:jid, GOC:sr] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002410 ! results in development of autonomic nervous system relationship: BFO:0000050 GO:0007399 ! part of nervous system development relationship: RO:0002296 UBERON:0002410 ! results in development of autonomic nervous system [Term] id: GO:0048485 name: sympathetic nervous system development namespace: biological_process def: "The process whose specific outcome is the progression of the sympathetic nervous system over time, from its formation to the mature structure. The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter." [FMA:9906, GOC:jid, GOC:sr] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000013 ! results in development of sympathetic nervous system relationship: BFO:0000050 GO:0048483 ! part of autonomic nervous system development relationship: RO:0002296 UBERON:0000013 ! results in development of sympathetic nervous system [Term] id: GO:0048505 name: regulation of timing of cell differentiation namespace: biological_process def: "The process controlling the activation and/or rate at which relatively unspecialized cells acquire specialized features. Any process that modulates the rate, frequency or extent of the XXX at a consistent predetermined time point during its development." [GOC:bf, GOC:dph, GOC:jid, GOC:tb] is_a: GO:0040034 ! regulation of development, heterochronic is_a: GO:0045595 ! regulation of cell differentiation [Term] id: GO:0048511 name: rhythmic process namespace: biological_process def: "Any process pertinent to the generation and maintenance of rhythms in the physiology of an organism." [GOC:jid] is_a: GO:0008150 ! biological_process relationship: RO:0002160 NCBITaxon:131567 ! only in taxon cellular organisms relationship: RO:0002162 NCBITaxon:131567 {all_only="true"} ! in taxon cellular organisms [Term] id: GO:0048513 name: animal organ development namespace: biological_process def: "Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." [GOC:dph, GOC:jid] synonym: "development of an organ" EXACT [] synonym: "organogenesis" EXACT [] xref: Wikipedia:Organogenesis is_a: GO:0048856 ! anatomical structure development [Term] id: GO:0048514 name: blood vessel morphogenesis namespace: biological_process def: "The process in which the anatomical structures of blood vessels are generated and organized. The blood vessel is the vasculature carrying blood." [GOC:jid] is_a: GO:0035239 ! tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001981 ! results in morphogenesis of blood vessel relationship: BFO:0000050 GO:0001568 ! part of blood vessel development relationship: RO:0002298 UBERON:0001981 ! results in morphogenesis of blood vessel [Term] id: GO:0048515 name: spermatid differentiation namespace: biological_process def: "The process whose specific outcome is the progression of a spermatid over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:dph, GOC:jid] synonym: "spermatid cell differentiation" EXACT [] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000018 ! results in acquisition of features of spermatid relationship: BFO:0000050 GO:0007283 ! part of spermatogenesis relationship: RO:0002315 CL:0000018 ! results in acquisition of features of spermatid [Term] id: GO:0048518 name: positive regulation of biological process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule." [GOC:jid] synonym: "positive regulation of physiological process" EXACT [] synonym: "up regulation of biological process" EXACT [] synonym: "up-regulation of biological process" EXACT [] synonym: "upregulation of biological process" EXACT [] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0008150 ! positively regulates biological_process relationship: RO:0002213 GO:0008150 ! positively regulates biological_process [Term] id: GO:0048519 name: negative regulation of biological process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule." [GOC:jid] synonym: "down regulation of biological process" EXACT [] synonym: "down-regulation of biological process" EXACT [] synonym: "downregulation of biological process" EXACT [] synonym: "negative regulation of physiological process" EXACT [] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0008150 ! negatively regulates biological_process relationship: RO:0002212 GO:0008150 ! negatively regulates biological_process [Term] id: GO:0048520 name: positive regulation of behavior namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli." [GOC:jid, GOC:pr] synonym: "up regulation of behavior" EXACT [] synonym: "up-regulation of behavior" EXACT [] synonym: "upregulation of behavior" EXACT [] is_a: GO:0050795 ! regulation of behavior is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007610 ! positively regulates behavior relationship: RO:0002213 GO:0007610 ! positively regulates behavior [Term] id: GO:0048521 name: negative regulation of behavior namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli." [GOC:jid, GOC:pr] synonym: "down regulation of behavior" EXACT [] synonym: "down-regulation of behavior" EXACT [] synonym: "downregulation of behavior" EXACT [] is_a: GO:0050795 ! regulation of behavior is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007610 ! negatively regulates behavior relationship: RO:0002212 GO:0007610 ! negatively regulates behavior [Term] id: GO:0048522 name: positive regulation of cellular process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:jid] synonym: "positive regulation of cellular physiological process" EXACT [] synonym: "up regulation of cellular process" EXACT [] synonym: "up-regulation of cellular process" EXACT [] synonym: "upregulation of cellular process" EXACT [] is_a: GO:0048518 ! positive regulation of biological process is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0009987 ! positively regulates cellular process relationship: RO:0002213 GO:0009987 ! positively regulates cellular process [Term] id: GO:0048523 name: negative regulation of cellular process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:jid] synonym: "down regulation of cellular process" EXACT [] synonym: "down-regulation of cellular process" EXACT [] synonym: "downregulation of cellular process" EXACT [] synonym: "negative regulation of cellular physiological process" EXACT [] is_a: GO:0048519 ! negative regulation of biological process is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0009987 ! negatively regulates cellular process relationship: RO:0002212 GO:0009987 ! negatively regulates cellular process [Term] id: GO:0048534 name: hematopoietic or lymphoid organ development namespace: biological_process def: "The process whose specific outcome is the progression of any organ involved in hematopoiesis (also known as hemopoiesis) or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation." [GOC:add, GOC:rl, ISBN:0781735149] synonym: "haematopoietic or lymphoid organ development" EXACT [] synonym: "haemopoietic or lymphoid organ development" EXACT [] synonym: "hemopoietic or lymphoid organ development" EXACT [] is_a: GO:0048513 ! animal organ development relationship: BFO:0000050 GO:0002520 ! part of immune system development [Term] id: GO:0048536 name: spleen development namespace: biological_process def: "The process whose specific outcome is the progression of the spleen over time, from its formation to the mature structure. The spleen is a large vascular lymphatic organ composed of white and red pulp, involved both in hemopoietic and immune system functions." [GOC:add, ISBN:0781735149] is_a: GO:0048534 ! hematopoietic or lymphoid organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002106 ! results in development of spleen relationship: RO:0002296 UBERON:0002106 ! results in development of spleen [Term] id: GO:0048539 name: bone marrow development namespace: biological_process def: "The process whose specific outcome is the progression of the bone marrow over time, from its formation to the mature structure." [GOC:add, ISBN:0781735149] is_a: GO:0009888 ! tissue development is_a: GO:0048534 ! hematopoietic or lymphoid organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002371 ! results in development of bone marrow relationship: BFO:0000050 GO:0060348 ! part of bone development relationship: RO:0002296 UBERON:0002371 ! results in development of bone marrow [Term] id: GO:0048545 name: response to steroid hormone namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus." [GOC:go_curators] synonym: "response to steroid hormone stimulus" EXACT [GOC:dos] is_a: GO:0009725 ! response to hormone is_a: GO:0014070 ! response to organic cyclic compound is_a: GO:0033993 ! response to lipid intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:26764 ! has primary input steroid hormone relationship: RO:0004009 CHEBI:26764 ! has primary input steroid hormone [Term] id: GO:0048546 name: digestive tract morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the digestive tract are generated and organized. The digestive tract is the anatomical structure through which food passes and is processed." [GOC:dph, GOC:go_curators, PMID:12618131] synonym: "alimentary canal morphogenesis" EXACT [] synonym: "digestive tube morphogenesis" EXACT [] synonym: "gastrointestinal tract morphogenesis" EXACT [] is_a: GO:0035239 ! tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001555 ! results in morphogenesis of digestive tract relationship: BFO:0000050 GO:0048565 ! part of digestive tract development relationship: RO:0002298 UBERON:0001555 ! results in morphogenesis of digestive tract [Term] id: GO:0048562 name: embryonic organ morphogenesis namespace: biological_process def: "Morphogenesis, during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." [GOC:jid] is_a: GO:0009887 ! animal organ morphogenesis is_a: GO:0048598 ! embryonic morphogenesis relationship: BFO:0000050 GO:0048568 ! part of embryonic organ development [Term] id: GO:0048565 name: digestive tract development namespace: biological_process def: "The process whose specific outcome is the progression of the digestive tract over time, from its formation to the mature structure. The digestive tract is the anatomical structure through which food passes and is processed." [GOC:go_curators] is_a: GO:0035295 ! tube development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001555 ! results in development of digestive tract relationship: BFO:0000050 GO:0055123 ! part of digestive system development relationship: RO:0002296 UBERON:0001555 ! results in development of digestive tract [Term] id: GO:0048568 name: embryonic organ development namespace: biological_process def: "Development, taking place during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." [GOC:jid] synonym: "embryonic organogenesis" EXACT [] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: BFO:0000050 GO:0009790 ! part of embryo development intersection_of: RO:0002296 UBERON:0000062 ! results in development of organ relationship: BFO:0000050 GO:0009790 ! part of embryo development relationship: RO:0002296 UBERON:0000062 ! results in development of organ [Term] id: GO:0048570 name: notochord morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the notochord are generated and organized. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column." [GOC:jid] is_a: GO:0048562 ! embryonic organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002328 ! results in morphogenesis of notochord relationship: BFO:0000050 GO:0030903 ! part of notochord development relationship: RO:0002298 UBERON:0002328 ! results in morphogenesis of notochord [Term] id: GO:0048580 name: regulation of post-embryonic development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure." [GOC:jid] is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0009791 ! regulates (processual) post-embryonic development relationship: RO:0002211 GO:0009791 ! regulates (processual) post-embryonic development [Term] id: GO:0048581 name: negative regulation of post-embryonic development namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure." [GOC:jid] synonym: "down regulation of post-embryonic development" EXACT [] synonym: "down-regulation of post-embryonic development" EXACT [] synonym: "downregulation of post-embryonic development" EXACT [] is_a: GO:0048580 ! regulation of post-embryonic development is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0009791 ! negatively regulates post-embryonic development relationship: RO:0002212 GO:0009791 ! negatively regulates post-embryonic development [Term] id: GO:0048582 name: positive regulation of post-embryonic development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure." [GOC:jid] synonym: "up regulation of post-embryonic development" EXACT [] synonym: "up-regulation of post-embryonic development" EXACT [] synonym: "upregulation of post-embryonic development" EXACT [] is_a: GO:0048580 ! regulation of post-embryonic development is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0009791 ! positively regulates post-embryonic development relationship: RO:0002213 GO:0009791 ! positively regulates post-embryonic development [Term] id: GO:0048583 name: regulation of response to stimulus namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus." [GOC:jid] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0050896 ! regulates (processual) response to stimulus relationship: RO:0002211 GO:0050896 ! regulates (processual) response to stimulus [Term] id: GO:0048584 name: positive regulation of response to stimulus namespace: biological_process def: "Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus." [GOC:jid] synonym: "up regulation of response to stimulus" EXACT [] synonym: "up-regulation of response to stimulus" EXACT [] synonym: "upregulation of response to stimulus" EXACT [] is_a: GO:0048518 ! positive regulation of biological process is_a: GO:0048583 ! regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0050896 ! positively regulates response to stimulus relationship: RO:0002213 GO:0050896 ! positively regulates response to stimulus [Term] id: GO:0048585 name: negative regulation of response to stimulus namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus." [GOC:jid] synonym: "down regulation of response to stimulus" EXACT [] synonym: "down-regulation of response to stimulus" EXACT [] synonym: "downregulation of response to stimulus" EXACT [] is_a: GO:0048519 ! negative regulation of biological process is_a: GO:0048583 ! regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0050896 ! negatively regulates response to stimulus relationship: RO:0002212 GO:0050896 ! negatively regulates response to stimulus [Term] id: GO:0048588 name: developmental cell growth namespace: biological_process def: "The growth of a cell, where growth contributes to the progression of the cell over time from one condition to another." [GOC:go_curators, GOC:isa_complete] synonym: "developmental growth of a unicellular organism" EXACT [] is_a: GO:0016049 ! cell growth is_a: GO:0048589 ! developmental growth relationship: BFO:0000050 GO:0048468 ! part of cell development [Term] id: GO:0048589 name: developmental growth namespace: biological_process def: "The increase in size or mass of an entire organism, a part of an organism or a cell, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another." [GOC:go_curators] is_a: GO:0040007 ! growth intersection_of: GO:0040007 ! growth intersection_of: BFO:0000050 GO:0032502 ! part of developmental process relationship: BFO:0000050 GO:0032502 ! part of developmental process [Term] id: GO:0048592 name: eye morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the eye are generated and organized." [GOC:jid, GOC:mtg_sensu] is_a: GO:0090596 ! sensory organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000970 ! results in morphogenesis of eye relationship: BFO:0000050 GO:0001654 ! part of eye development relationship: RO:0002298 UBERON:0000970 ! results in morphogenesis of eye [Term] id: GO:0048593 name: camera-type eye morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the eye are generated and organized. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field." [GOC:jid, GOC:mtg_sensu] synonym: "camera-style eye morphogenesis" EXACT [GOC:dph] is_a: GO:0048592 ! eye morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000019 ! results in morphogenesis of camera-type eye relationship: BFO:0000050 GO:0043010 ! part of camera-type eye development relationship: RO:0002298 UBERON:0000019 ! results in morphogenesis of camera-type eye [Term] id: GO:0048596 name: embryonic camera-type eye morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the eye are generated and organized during embryonic development." [GOC:jid, GOC:mtg_sensu] is_a: GO:0048048 ! embryonic eye morphogenesis relationship: BFO:0000050 GO:0031076 ! part of embryonic camera-type eye development relationship: BFO:0000050 GO:0048593 ! part of camera-type eye morphogenesis [Term] id: GO:0048598 name: embryonic morphogenesis namespace: biological_process def: "The process in which anatomical structures are generated and organized during the embryonic phase. The embryonic phase begins with zygote formation. The end of the embryonic phase is organism-specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants." [GOC:jid, GOC:mtg_sensu] synonym: "embryonic anatomical structure morphogenesis" EXACT [GOC:dph, GOC:tb] is_a: GO:0009653 ! anatomical structure morphogenesis relationship: BFO:0000050 GO:0009790 ! part of embryo development [Term] id: GO:0048599 name: oocyte development namespace: biological_process def: "The process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." [GOC:go_curators] is_a: GO:0007281 ! germ cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000023 ! results in development of oocyte relationship: BFO:0000050 GO:0009994 ! part of oocyte differentiation relationship: RO:0002296 CL:0000023 ! results in development of oocyte [Term] id: GO:0048601 name: oocyte morphogenesis namespace: biological_process def: "The process in which the structures of an oocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of an oocyte." [GOC:go_curators] synonym: "oocyte morphogenesis during differentiation" EXACT [] is_a: GO:0000902 ! cell morphogenesis is_a: GO:0003006 ! developmental process involved in reproduction intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 CL:0000023 ! results in morphogenesis of oocyte relationship: BFO:0000050 GO:0048599 ! part of oocyte development relationship: RO:0002160 NCBITaxon:33208 ! only in taxon Metazoa relationship: RO:0002162 NCBITaxon:33208 {all_only="true"} ! in taxon Metazoa relationship: RO:0002298 CL:0000023 ! results in morphogenesis of oocyte [Term] id: GO:0048608 name: reproductive structure development namespace: biological_process def: "The reproductive developmental process whose specific outcome is the progression of somatic structures that will be used in the process of creating new individuals from one or more parents, from their formation to the mature structures." [GOC:dph, GOC:isa_complete, GOC:jid] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0048856 ! anatomical structure development relationship: BFO:0000050 GO:0061458 ! part of reproductive system development [Term] id: GO:0048609 name: multicellular organismal reproductive process namespace: biological_process def: "The process, occurring above the cellular level, that is pertinent to the reproductive function of a multicellular organism. This includes the integrated processes at the level of tissues and organs." [GOC:dph, GOC:jid, GOC:tb] synonym: "reproductive process in a multicellular organism" EXACT [] is_a: GO:0022414 ! reproductive process relationship: BFO:0000050 GO:0032504 ! part of multicellular organism reproduction [Term] id: GO:0048627 name: myoblast development namespace: biological_process def: "The process whose specific outcome is the progression of the myoblast over time, from its formation to the mature structure. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:dph, GOC:mtg_muscle] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000056 ! results in development of myoblast relationship: BFO:0000050 GO:0045445 ! part of myoblast differentiation relationship: RO:0002296 CL:0000056 ! results in development of myoblast [Term] id: GO:0048628 name: myoblast maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for a myoblast to attain its fully functional state. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:dph, GOC:mtg_muscle] is_a: GO:0048469 ! cell maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 CL:0000056 ! results in maturation of myoblast relationship: BFO:0000050 GO:0048627 ! part of myoblast development relationship: RO:0002299 CL:0000056 ! results in maturation of myoblast [Term] id: GO:0048630 name: skeletal muscle tissue growth namespace: biological_process def: "The increase in size or mass of a skeletal muscle. This may be due to a change in the fiber number or size." [GOC:lm, PMID:15726494, PMID:15907921] is_a: GO:0048589 ! developmental growth intersection_of: GO:0048589 ! developmental growth intersection_of: RO:0002343 UBERON:0001134 ! results in growth of skeletal muscle tissue relationship: BFO:0000050 GO:0007519 ! part of skeletal muscle tissue development relationship: RO:0002343 UBERON:0001134 ! results in growth of skeletal muscle tissue [Term] id: GO:0048631 name: regulation of skeletal muscle tissue growth namespace: biological_process def: "Any process that modulates the frequency, rate or extent of skeletal muscle growth." [GOC:lm, PMID:15726494, PMID:15907921] is_a: GO:0048638 ! regulation of developmental growth intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048630 ! regulates (processual) skeletal muscle tissue growth relationship: RO:0002211 GO:0048630 ! regulates (processual) skeletal muscle tissue growth [Term] id: GO:0048632 name: negative regulation of skeletal muscle tissue growth namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle growth." [GOC:lm, PMID:15726494, PMID:15907921] synonym: "down regulation of skeletal muscle growth" EXACT [] synonym: "down-regulation of skeletal muscle growth" EXACT [] synonym: "downregulation of skeletal muscle growth" EXACT [] is_a: GO:0048631 ! regulation of skeletal muscle tissue growth is_a: GO:0048640 ! negative regulation of developmental growth intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048630 ! negatively regulates skeletal muscle tissue growth relationship: RO:0002212 GO:0048630 ! negatively regulates skeletal muscle tissue growth [Term] id: GO:0048633 name: positive regulation of skeletal muscle tissue growth namespace: biological_process def: "Any process that activates, maintains or increases the rate of skeletal muscle growth." [GOC:lm, PMID:15726494, PMID:15907921] synonym: "up regulation of skeletal muscle growth" EXACT [] synonym: "up-regulation of skeletal muscle growth" EXACT [] synonym: "upregulation of skeletal muscle growth" EXACT [] is_a: GO:0048631 ! regulation of skeletal muscle tissue growth is_a: GO:0048639 ! positive regulation of developmental growth is_a: GO:0048643 ! positive regulation of skeletal muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0048630 ! positively regulates skeletal muscle tissue growth relationship: RO:0002213 GO:0048630 ! positively regulates skeletal muscle tissue growth [Term] id: GO:0048634 name: regulation of muscle organ development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of muscle development." [GOC:go_curators] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007517 ! regulates (processual) muscle organ development relationship: RO:0002211 GO:0007517 ! regulates (processual) muscle organ development [Term] id: GO:0048635 name: negative regulation of muscle organ development namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of muscle development." [GOC:go_curators] synonym: "down regulation of muscle development" EXACT [] synonym: "down-regulation of muscle development" EXACT [] synonym: "downregulation of muscle development" EXACT [] is_a: GO:0048634 ! regulation of muscle organ development is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007517 ! negatively regulates muscle organ development relationship: RO:0002212 GO:0007517 ! negatively regulates muscle organ development [Term] id: GO:0048636 name: positive regulation of muscle organ development namespace: biological_process def: "Any process that activates, maintains or increases the rate of muscle development." [GOC:go_curators] synonym: "up regulation of muscle development" EXACT [] synonym: "up-regulation of muscle development" EXACT [] synonym: "upregulation of muscle development" EXACT [] is_a: GO:0048634 ! regulation of muscle organ development is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007517 ! positively regulates muscle organ development relationship: RO:0002213 GO:0007517 ! positively regulates muscle organ development [Term] id: GO:0048638 name: regulation of developmental growth namespace: biological_process def: "Any process that modulates the frequency, rate or extent of developmental growth." [GOC:go_curators] is_a: GO:0040008 ! regulation of growth is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048589 ! regulates (processual) developmental growth relationship: RO:0002211 GO:0048589 ! regulates (processual) developmental growth [Term] id: GO:0048639 name: positive regulation of developmental growth namespace: biological_process def: "Any process that activates, maintains or increases the rate of developmental growth." [GOC:go_curators] synonym: "up regulation of developmental growth" EXACT [] synonym: "up-regulation of developmental growth" EXACT [] synonym: "upregulation of developmental growth" EXACT [] is_a: GO:0045927 ! positive regulation of growth is_a: GO:0048638 ! regulation of developmental growth is_a: GO:0051094 ! positive regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0048589 ! positively regulates developmental growth relationship: RO:0002213 GO:0048589 ! positively regulates developmental growth [Term] id: GO:0048640 name: negative regulation of developmental growth namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of developmental growth." [GOC:go_curators] synonym: "down regulation of developmental growth" EXACT [] synonym: "down-regulation of developmental growth" EXACT [] synonym: "downregulation of developmental growth" EXACT [] is_a: GO:0045926 ! negative regulation of growth is_a: GO:0048638 ! regulation of developmental growth is_a: GO:0051093 ! negative regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048589 ! negatively regulates developmental growth relationship: RO:0002212 GO:0048589 ! negatively regulates developmental growth [Term] id: GO:0048641 name: regulation of skeletal muscle tissue development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of skeletal muscle tissue development." [GOC:go_curators] is_a: GO:0016202 ! regulation of striated muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007519 ! regulates (processual) skeletal muscle tissue development relationship: RO:0002211 GO:0007519 ! regulates (processual) skeletal muscle tissue development [Term] id: GO:0048642 name: negative regulation of skeletal muscle tissue development namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle tissue development." [GOC:go_curators] synonym: "down regulation of skeletal muscle development" EXACT [] synonym: "down-regulation of skeletal muscle development" EXACT [] synonym: "downregulation of skeletal muscle development" EXACT [] is_a: GO:0045843 ! negative regulation of striated muscle tissue development is_a: GO:0048641 ! regulation of skeletal muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007519 ! negatively regulates skeletal muscle tissue development relationship: RO:0002212 GO:0007519 ! negatively regulates skeletal muscle tissue development [Term] id: GO:0048643 name: positive regulation of skeletal muscle tissue development namespace: biological_process def: "Any process that activates, maintains or increases the rate of skeletal muscle tissue development." [GOC:go_curators] synonym: "up regulation of skeletal muscle development" EXACT [] synonym: "up-regulation of skeletal muscle development" EXACT [] synonym: "upregulation of skeletal muscle development" EXACT [] is_a: GO:0045844 ! positive regulation of striated muscle tissue development is_a: GO:0048641 ! regulation of skeletal muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007519 ! positively regulates skeletal muscle tissue development relationship: RO:0002213 GO:0007519 ! positively regulates skeletal muscle tissue development [Term] id: GO:0048644 name: muscle organ morphogenesis namespace: biological_process def: "The process in which the anatomical structures of muscle are generated and organized." [GOC:jid] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001630 ! results in morphogenesis of muscle organ relationship: BFO:0000050 GO:0007517 ! part of muscle organ development relationship: RO:0002298 UBERON:0001630 ! results in morphogenesis of muscle organ [Term] id: GO:0048645 name: animal organ formation namespace: biological_process def: "The process pertaining to the initial formation of an animal organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment. Organs are a natural part or structure in an animal or a plant, capable of performing some special action (termed its function), which is essential to the life or well-being of the whole. The heart and lungs are organs of animals, and the petal and leaf are organs of plants. In animals the organs are generally made up of several tissues, one of which usually predominates, and determines the principal function of the organ." [GOC:dph, GOC:jid] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0003103 ! results in formation of anatomical entity compound organ relationship: BFO:0000050 GO:0009887 ! part of animal organ morphogenesis relationship: RO:0002297 UBERON:0003103 ! results in formation of anatomical entity compound organ [Term] id: GO:0048646 name: anatomical structure formation involved in morphogenesis namespace: biological_process def: "The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." [GOC:dph, GOC:jid, GOC:tb] synonym: "formation of an anatomical structure involved in morphogenesis" EXACT [GOC:dph, GOC:tb] is_a: GO:0032502 ! developmental process relationship: BFO:0000050 GO:0009653 ! part of anatomical structure morphogenesis [Term] id: GO:0048659 name: smooth muscle cell proliferation namespace: biological_process def: "The multiplication or reproduction of smooth muscle cells, resulting in the expansion of a cell population." [CL:0000192, GOC:ebc, PMID:1840698] synonym: "SMC proliferation" EXACT [] is_a: GO:0033002 ! muscle cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000192 ! acts on population of smooth muscle cell relationship: RO:0012003 CL:0000192 ! acts on population of smooth muscle cell [Term] id: GO:0048660 name: regulation of smooth muscle cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of smooth muscle cell proliferation." [CL:0000192, GOC:ebc] synonym: "regulation of SMC proliferation" EXACT [] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048659 ! regulates (processual) smooth muscle cell proliferation relationship: RO:0002211 GO:0048659 ! regulates (processual) smooth muscle cell proliferation [Term] id: GO:0048661 name: positive regulation of smooth muscle cell proliferation namespace: biological_process def: "Any process that activates or increases the rate or extent of smooth muscle cell proliferation." [CL:0000192, GOC:ebc] synonym: "positive regulation of SMC proliferation" EXACT [] synonym: "up regulation of smooth muscle cell proliferation" EXACT [] synonym: "up-regulation of smooth muscle cell proliferation" EXACT [] synonym: "upregulation of smooth muscle cell proliferation" EXACT [] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0048660 ! regulation of smooth muscle cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0048659 ! positively regulates smooth muscle cell proliferation relationship: RO:0002213 GO:0048659 ! positively regulates smooth muscle cell proliferation [Term] id: GO:0048662 name: negative regulation of smooth muscle cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of smooth muscle cell proliferation." [CL:0000192, GOC:ebc] synonym: "down regulation of smooth muscle cell proliferation" EXACT [] synonym: "down-regulation of smooth muscle cell proliferation" EXACT [] synonym: "downregulation of smooth muscle cell proliferation" EXACT [] synonym: "negative regulation of SMC proliferation" EXACT [] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0048660 ! regulation of smooth muscle cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048659 ! negatively regulates smooth muscle cell proliferation relationship: RO:0002212 GO:0048659 ! negatively regulates smooth muscle cell proliferation [Term] id: GO:0048666 name: neuron development namespace: biological_process def: "The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:dph] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000540 ! results in development of neuron relationship: BFO:0000050 GO:0030182 ! part of neuron differentiation relationship: RO:0002296 CL:0000540 ! results in development of neuron [Term] id: GO:0048667 name: cell morphogenesis involved in neuron differentiation namespace: biological_process def: "The process in which the structures of a neuron are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a neuron." [GOC:dph, GOC:tb] synonym: "neuron morphogenesis involved in differentiation" EXACT [GOC:dph, GOC:tb] is_a: GO:0000902 ! cell morphogenesis intersection_of: GO:0000902 ! cell morphogenesis intersection_of: BFO:0000050 GO:0030182 ! part of neuron differentiation relationship: BFO:0000050 GO:0048666 ! part of neuron development [Term] id: GO:0048699 name: generation of neurons namespace: biological_process def: "The process in which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons." [GOC:nln] synonym: "neuron generation" EXACT [] is_a: GO:0022008 ! neurogenesis [Term] id: GO:0048705 name: skeletal system morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the skeleton are generated and organized." [GOC:dph, GOC:dsf, GOC:jid, GOC:tb] synonym: "skeletal morphogenesis" EXACT [GOC:dph, GOC:tb] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001434 ! results in morphogenesis of skeletal system relationship: BFO:0000050 GO:0001501 ! part of skeletal system development relationship: RO:0002298 UBERON:0001434 ! results in morphogenesis of skeletal system [Term] id: GO:0048729 name: tissue morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a tissue are generated and organized." [GOC:dph, GOC:jid] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000479 ! results in morphogenesis of tissue relationship: BFO:0000050 GO:0009888 ! part of tissue development relationship: RO:0002298 UBERON:0000479 ! results in morphogenesis of tissue [Term] id: GO:0048730 name: epidermis morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the epidermis are generated and organized. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species." [GOC:jid, UBERON:0001003] is_a: GO:0002009 ! morphogenesis of an epithelium intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0007376 ! results in morphogenesis of outer epithelium relationship: BFO:0000050 GO:0008544 ! part of epidermis development relationship: RO:0002298 UBERON:0007376 ! results in morphogenesis of outer epithelium [Term] id: GO:0048731 name: system development namespace: biological_process def: "The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process." [GOC:dph, GOC:jid] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000467 ! results in development of anatomical system relationship: BFO:0000050 GO:0007275 ! part of multicellular organism development relationship: RO:0002296 UBERON:0000467 ! results in development of anatomical system [Term] id: GO:0048732 name: gland development namespace: biological_process def: "The process whose specific outcome is the progression of a gland over time, from its formation to the mature structure. A gland is an organ specialised for secretion." [GOC:jid] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002530 ! results in development of gland relationship: RO:0002296 UBERON:0002530 ! results in development of gland [Term] id: GO:0048736 name: appendage development namespace: biological_process def: "The process whose specific outcome is the progression of an appendage over time, from its formation to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch." [GOC:jid, GOC:rc] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000026 ! results in development of appendage relationship: BFO:0000050 GO:0007275 ! part of multicellular organism development relationship: RO:0002296 UBERON:0000026 ! results in development of appendage [Term] id: GO:0048738 name: cardiac muscle tissue development namespace: biological_process def: "The process whose specific outcome is the progression of cardiac muscle over time, from its formation to the mature structure." [GOC:dph, GOC:jid, GOC:lm] synonym: "heart muscle development" EXACT [] is_a: GO:0014706 ! striated muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001133 ! results in development of cardiac muscle tissue relationship: BFO:0000050 GO:0007507 ! part of heart development relationship: RO:0002296 UBERON:0001133 ! results in development of cardiac muscle tissue [Term] id: GO:0048741 name: skeletal muscle fiber development namespace: biological_process def: "The process whose specific outcome is the progression of the skeletal muscle fiber over time, from its formation to the mature structure. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast." [GOC:dph, GOC:ef, GOC:jid, GOC:lm, GOC:mtg_muscle] synonym: "skeletal muscle fibre development" EXACT [] synonym: "skeletal myofiber development" EXACT [] synonym: "skeletal myofibre development" EXACT [] is_a: GO:0014904 ! myotube cell development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 CL:0008002 ! results in development of skeletal muscle fiber relationship: BFO:0000050 GO:0007519 ! part of skeletal muscle tissue development relationship: RO:0002296 CL:0008002 ! results in development of skeletal muscle fiber [Term] id: GO:0048742 name: regulation of skeletal muscle fiber development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast." [GOC:dph, GOC:jid, GOC:mtg_muscle, GOC:sm] synonym: "regulation of skeletal muscle fibre development" EXACT [] synonym: "regulation of skeletal myofiber development" EXACT [] synonym: "regulation of skeletal myofibre development" EXACT [] is_a: GO:0010830 ! regulation of myotube differentiation is_a: GO:0060284 ! regulation of cell development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048741 ! regulates (processual) skeletal muscle fiber development relationship: RO:0002211 GO:0048741 ! regulates (processual) skeletal muscle fiber development [Term] id: GO:0048743 name: positive regulation of skeletal muscle fiber development namespace: biological_process def: "Any process that activates, maintains or increases the rate of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast." [GOC:dph, GOC:jid, GOC:lm, GOC:mtg_muscle] synonym: "positive regulation of skeletal muscle fibre development" EXACT [] synonym: "positive regulation of skeletal myofiber development" EXACT [] synonym: "positive regulation of skeletal myofibre development" EXACT [] synonym: "up regulation of skeletal muscle fiber development" EXACT [] synonym: "up-regulation of skeletal muscle fiber development" EXACT [] synonym: "upregulation of skeletal muscle fiber development" EXACT [] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0048643 ! positive regulation of skeletal muscle tissue development is_a: GO:0048742 ! regulation of skeletal muscle fiber development is_a: GO:0051155 ! positive regulation of striated muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0048741 ! positively regulates skeletal muscle fiber development relationship: RO:0002213 GO:0048741 ! positively regulates skeletal muscle fiber development [Term] id: GO:0048744 name: negative regulation of skeletal muscle fiber development namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast." [GOC:dph, GOC:jid, GOC:lm, GOC:mtg_muscle] synonym: "down regulation of skeletal muscle fiber development" EXACT [] synonym: "down-regulation of skeletal muscle fiber development" EXACT [] synonym: "downregulation of skeletal muscle fiber development" EXACT [] synonym: "negative regulation of skeletal muscle fibre development" EXACT [] synonym: "negative regulation of skeletal myofiber development" EXACT [] synonym: "negative regulation of skeletal myofibre development" EXACT [] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0048742 ! regulation of skeletal muscle fiber development is_a: GO:0051154 ! negative regulation of striated muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048741 ! negatively regulates skeletal muscle fiber development relationship: RO:0002212 GO:0048741 ! negatively regulates skeletal muscle fiber development [Term] id: GO:0048745 name: smooth muscle tissue development namespace: biological_process def: "The process whose specific outcome is the progression of smooth muscle over time, from its formation to the mature structure." [GOC:dph, GOC:jid, GOC:lm] is_a: GO:0060537 ! muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001135 ! results in development of smooth muscle tissue relationship: RO:0002296 UBERON:0001135 ! results in development of smooth muscle tissue [Term] id: GO:0048749 name: compound eye development namespace: biological_process def: "The process whose specific outcome is the progression of the compound eye over time, from its formation to the mature structure. The compound eye is an organ of sight that contains multiple repeating units, often arranged hexagonally. Each unit has its own lens and photoreceptor cell(s) and can generate either a single pixelated image or multiple images, per eye." [GOC:jid, GOC:mtg_sensu, Wikipedia:Eye] synonym: "insect-type retina development" EXACT [PMID:11735386] is_a: GO:0001654 ! eye development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000018 ! results in development of compound eye relationship: RO:0002296 UBERON:0000018 ! results in development of compound eye [Term] id: GO:0048753 name: pigment granule organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pigment granule." [GOC:rc] synonym: "pigment granule organisation" EXACT [] is_a: GO:0016050 ! vesicle organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0048770 ! results in organization of pigment granule relationship: BFO:0000050 GO:0033059 ! part of cellular pigmentation relationship: RO:0002592 GO:0048770 ! results in organization of pigment granule [Term] id: GO:0048754 name: branching morphogenesis of an epithelial tube namespace: biological_process def: "The process in which the anatomical structures of branches in an epithelial tube are generated and organized. A tube is a long hollow cylinder." [GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0035239 ! tube morphogenesis is_a: GO:0061138 ! morphogenesis of a branching epithelium intersection_of: GO:0001763 ! morphogenesis of a branching structure intersection_of: RO:0002298 UBERON:0000025 ! results in morphogenesis of tube relationship: BFO:0000050 GO:0060562 ! part of epithelial tube morphogenesis [Term] id: GO:0048755 name: branching morphogenesis of a nerve namespace: biological_process def: "The process in which the anatomical structures of branches in a nerve are generated and organized. This term refers to an anatomical structure (nerve) not a cell (neuron)." [GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0001763 ! morphogenesis of a branching structure intersection_of: GO:0001763 ! morphogenesis of a branching structure intersection_of: RO:0002298 UBERON:0001021 ! results in morphogenesis of nerve relationship: BFO:0000050 GO:0007399 ! part of nervous system development relationship: RO:0002298 UBERON:0001021 ! results in morphogenesis of nerve [Term] id: GO:0048762 name: mesenchymal cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types." [GOC:dph, GOC:jid] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0008019 ! results in acquisition of features of mesenchymal cell relationship: BFO:0000050 GO:0060485 ! part of mesenchyme development relationship: RO:0002315 CL:0008019 ! results in acquisition of features of mesenchymal cell [Term] id: GO:0048770 name: pigment granule namespace: cellular_component def: "A small, subcellular membrane-bounded vesicle containing pigment and/or pigment precursor molecules. Pigment granule biogenesis is poorly understood, as pigment granules are derived from multiple sources including the endoplasmic reticulum, coated vesicles, lysosomes, and endosomes." [GOC:jid, GOC:mh] is_a: GO:0031410 ! cytoplasmic vesicle [Term] id: GO:0048793 name: pronephros development namespace: biological_process def: "The process whose specific outcome is the progression of the pronephros over time, from its formation to the mature structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life." [GOC:bf, GOC:mtg_kidney_jan10, PMID:10535314, PMID:15968585, PMID:18322540, XAO:00002000, ZFA:0000151] synonym: "pronephric kidney development" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0001822 ! kidney development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002120 ! results in development of pronephros relationship: RO:0002296 UBERON:0002120 ! results in development of pronephros [Term] id: GO:0048799 name: animal organ maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for an animal organ to attain its fully functional state. An organ is a tissue or set of tissues that work together to perform a specific function or functions." [GOC:curators] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 UBERON:0000062 ! results in maturation of organ relationship: BFO:0000050 GO:0048513 ! part of animal organ development relationship: RO:0002299 UBERON:0000062 ! results in maturation of organ [Term] id: GO:0048806 name: genitalia development namespace: biological_process def: "The process whose specific outcome is the progression of the genitalia over time, from its formation to the mature structure." [GOC:jid] synonym: "genital development" EXACT [] is_a: GO:0048513 ! animal organ development is_a: GO:0048608 ! reproductive structure development relationship: BFO:0000050 GO:0007548 ! part of sex differentiation [Term] id: GO:0048808 name: male genitalia morphogenesis namespace: biological_process def: "The process in which the anatomical structures of male genitalia are generated and organized." [GOC:ems, ISBN:0140512888] is_a: GO:0035112 ! genitalia morphogenesis is_a: GO:0090598 ! male anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000079 ! results in morphogenesis of male reproductive system relationship: BFO:0000050 GO:0030539 ! part of male genitalia development relationship: RO:0002298 UBERON:0000079 ! results in morphogenesis of male reproductive system [Term] id: GO:0048812 name: neuron projection morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites." [GOC:mah] is_a: GO:0120039 ! plasma membrane bounded cell projection morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 GO:0043005 ! results in morphogenesis of neuron projection relationship: BFO:0000050 GO:0031175 ! part of neuron projection development relationship: RO:0002298 GO:0043005 ! results in morphogenesis of neuron projection [Term] id: GO:0048821 name: erythrocyte development namespace: biological_process def: "The process whose specific outcome is the progression of an erythrocyte over time, from its formation to the mature structure." [GOC:devbiol] synonym: "RBC development" EXACT [CL:0000232] synonym: "red blood cell development" EXACT [CL:0000232] is_a: GO:0061515 ! myeloid cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000232 ! results in development of erythrocyte relationship: BFO:0000050 GO:0030218 ! part of erythrocyte differentiation relationship: RO:0002296 CL:0000232 ! results in development of erythrocyte [Term] id: GO:0048822 name: enucleate erythrocyte development namespace: biological_process def: "The process aimed at the progression of an enucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:devbiol] synonym: "enucleate RBC development" EXACT [CL:0000232] synonym: "enucleate red blood cell development" EXACT [CL:0000232] is_a: GO:0048821 ! erythrocyte development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000595 ! results in development of enucleate erythrocyte relationship: BFO:0000050 GO:0043353 ! part of enucleate erythrocyte differentiation relationship: RO:0002296 CL:0000595 ! results in development of enucleate erythrocyte [Term] id: GO:0048823 name: nucleate erythrocyte development namespace: biological_process def: "The process aimed at the progression of a nucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:devbiol] synonym: "nucleate RBC development" EXACT [CL:0000232] synonym: "nucleate red blood cell development" EXACT [CL:0000232] is_a: GO:0048821 ! erythrocyte development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000562 ! results in development of nucleate erythrocyte relationship: BFO:0000050 GO:0043363 ! part of nucleate erythrocyte differentiation relationship: RO:0002296 CL:0000562 ! results in development of nucleate erythrocyte [Term] id: GO:0048844 name: artery morphogenesis namespace: biological_process def: "The process in which the anatomical structures of arterial blood vessels are generated and organized. Arteries are blood vessels that transport blood from the heart to the body and its organs." [GOC:dsf, PMID:16740480] synonym: "arterial morphogenesis" EXACT [] synonym: "arteriogenesis" EXACT [GOC:mtg_heart] is_a: GO:0048514 ! blood vessel morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001637 ! results in morphogenesis of artery relationship: BFO:0000050 GO:0060840 ! part of artery development relationship: RO:0002298 UBERON:0001637 ! results in morphogenesis of artery [Term] id: GO:0048845 name: venous blood vessel morphogenesis namespace: biological_process def: "The process in which the anatomical structures of venous blood vessels are generated and organized. Veins are blood vessels that transport blood from the body and its organs to the heart." [GOC:dsf, PMID:16740480] synonym: "venous morphogenesis" EXACT [] is_a: GO:0048514 ! blood vessel morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001638 ! results in morphogenesis of vein relationship: BFO:0000050 GO:0060841 ! part of venous blood vessel development relationship: RO:0002298 UBERON:0001638 ! results in morphogenesis of vein [Term] id: GO:0048854 name: brain morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the brain are generated and organized. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)." [GOC:dgh, GOC:jid] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000955 ! results in morphogenesis of brain relationship: BFO:0000050 GO:0007420 ! part of brain development relationship: RO:0002298 UBERON:0000955 ! results in morphogenesis of brain [Term] id: GO:0048856 name: anatomical structure development namespace: biological_process def: "The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." [GO_REF:0000021] synonym: "development of an anatomical structure" EXACT [] is_a: GO:0032502 ! developmental process intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 UBERON:0000061 ! results in development of anatomical structure relationship: RO:0002296 UBERON:0000061 ! results in development of anatomical structure [Term] id: GO:0048857 name: neural nucleus development namespace: biological_process def: "The biological process whose specific outcome is the progression of a neural nucleus from its initial condition to its mature state. A neural nucleus is an anatomical structure consisting of a discrete aggregate of neuronal soma." [GO_REF:0000021] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000125 ! results in development of neural nucleus relationship: RO:0002296 UBERON:0000125 ! results in development of neural nucleus [Term] id: GO:0048858 name: cell projection morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a cell projection are generated and organized." [GO_REF:0000021] is_a: GO:0030030 ! cell projection organization is_a: GO:0032989 ! cellular anatomical entity morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 GO:0042995 ! results in morphogenesis of cell projection relationship: BFO:0000050 GO:0000902 ! part of cell morphogenesis relationship: RO:0002298 GO:0042995 ! results in morphogenesis of cell projection [Term] id: GO:0048859 name: formation of anatomical boundary namespace: biological_process def: "The process in which the limits of an anatomical structure are generated. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." [GO_REF:0000021] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0007651 ! results in formation of anatomical entity anatomical junction relationship: RO:0002297 UBERON:0007651 ! results in formation of anatomical entity anatomical junction [Term] id: GO:0048863 name: stem cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [CL:0000034, GOC:isa_complete] xref: Wikipedia:Stem_cell_differentiation is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000034 ! results in acquisition of features of stem cell relationship: RO:0002315 CL:0000034 ! results in acquisition of features of stem cell [Term] id: GO:0048864 name: stem cell development namespace: biological_process def: "The process whose specific outcome is the progression of the stem cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to its specific fate." [CL:0000034, GOC:isa_complete] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000034 ! results in development of stem cell relationship: BFO:0000050 GO:0048863 ! part of stem cell differentiation relationship: RO:0002296 CL:0000034 ! results in development of stem cell [Term] id: GO:0048869 name: cellular developmental process namespace: biological_process def: "A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition." [GOC:isa_complete] is_a: GO:0009987 ! cellular process is_a: GO:0032502 ! developmental process [Term] id: GO:0048870 name: cell motility namespace: biological_process def: "Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another." [GOC:dgh, GOC:dph, GOC:isa_complete, GOC:mlg] synonym: "cell locomotion" EXACT [] synonym: "movement of a cell" EXACT [] is_a: GO:0009987 ! cellular process [Term] id: GO:0048871 name: multicellular organismal-level homeostasis namespace: biological_process def: "Any process involved in the maintenance of an internal steady state at the level of the multicellular organism." [GOC:isa_complete] is_a: GO:0032501 ! multicellular organismal process is_a: GO:0042592 ! homeostatic process [Term] id: GO:0048872 name: homeostasis of number of cells namespace: biological_process def: "Any biological process involved in the maintenance of the steady-state number of cells within a population of cells." [GOC:isa_complete] synonym: "cell population homeostasis" EXACT [] synonym: "homeostasis of cell number" EXACT [GOC:dph] is_a: GO:0048871 ! multicellular organismal-level homeostasis [Term] id: GO:0048880 name: sensory system development namespace: biological_process def: "The process whose specific outcome is the progression of a sensory system over time from its formation to the mature structure." [GOC:dgh] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001032 ! results in development of sensory system relationship: RO:0002296 UBERON:0001032 ! results in development of sensory system [Term] id: GO:0048934 name: peripheral nervous system neuron differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the peripheral nervous system." [GOC:dgh] is_a: GO:0030182 ! neuron differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:2000032 ! results in acquisition of features of peripheral nervous system neuron relationship: BFO:0000050 GO:0007422 ! part of peripheral nervous system development relationship: RO:0002315 CL:2000032 ! results in acquisition of features of peripheral nervous system neuron [Term] id: GO:0048935 name: peripheral nervous system neuron development namespace: biological_process def: "The process whose specific outcome is the progression of a neuron whose cell body is located in the peripheral nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron." [GOC:dgh] is_a: GO:0048666 ! neuron development intersection_of: GO:0048468 ! cell development intersection_of: RO:0002296 CL:2000032 ! results in development of peripheral nervous system neuron relationship: BFO:0000050 GO:0048934 ! part of peripheral nervous system neuron differentiation relationship: RO:0002296 CL:2000032 ! results in development of peripheral nervous system neuron [Term] id: GO:0050000 name: chromosome localization namespace: biological_process def: "Any process in which a chromosome is transported to, or maintained in, a specific location." [GOC:ai] synonym: "chromosome localisation" EXACT [GOC:mah] synonym: "establishment and maintenance of chromosome localization" EXACT [] synonym: "establishment and maintenance of chromosome position" EXACT [] is_a: GO:0051640 ! organelle localization intersection_of: GO:0051179 ! localization intersection_of: RO:0004009 GO:0005694 ! has primary input chromosome relationship: RO:0004009 GO:0005694 ! has primary input chromosome [Term] id: GO:0050432 name: catecholamine secretion namespace: biological_process def: "The regulated release of catecholamines by a cell. The catecholamines are a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." [GOC:ai, GOC:ef] is_a: GO:0032940 ! secretion by cell is_a: GO:0051937 ! catecholamine transport intersection_of: GO:0046903 ! secretion intersection_of: RO:0004009 CHEBI:33567 ! has primary input catecholamine [Term] id: GO:0050433 name: regulation of catecholamine secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of catecholamines." [GOC:ai] is_a: GO:0051952 ! regulation of amine transport is_a: GO:1903530 ! regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0050432 ! regulates (processual) catecholamine secretion relationship: RO:0002211 GO:0050432 ! regulates (processual) catecholamine secretion [Term] id: GO:0050657 name: nucleic acid transport namespace: biological_process def: "The directed movement of nucleic acids, single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai, ISBN:0198506732] is_a: GO:0015931 ! nucleobase-containing compound transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:33696 ! has primary input nucleic acid relationship: RO:0004009 CHEBI:33696 ! has primary input nucleic acid [Term] id: GO:0050658 name: RNA transport namespace: biological_process def: "The directed movement of RNA, ribonucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] is_a: GO:0050657 ! nucleic acid transport is_a: GO:0051236 ! establishment of RNA localization intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:33697 ! has primary input ribonucleic acid relationship: RO:0004009 CHEBI:33697 ! has primary input ribonucleic acid [Term] id: GO:0050670 name: regulation of lymphocyte proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of lymphocyte proliferation." [GOC:ai] is_a: GO:0032944 ! regulation of mononuclear cell proliferation is_a: GO:0051249 ! regulation of lymphocyte activation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0046651 ! regulates (processual) lymphocyte proliferation relationship: RO:0002211 GO:0046651 ! regulates (processual) lymphocyte proliferation [Term] id: GO:0050671 name: positive regulation of lymphocyte proliferation namespace: biological_process def: "Any process that activates or increases the rate or extent of lymphocyte proliferation." [GOC:ai] synonym: "up regulation of lymphocyte proliferation" EXACT [] synonym: "up-regulation of lymphocyte proliferation" EXACT [] synonym: "upregulation of lymphocyte proliferation" EXACT [] is_a: GO:0032946 ! positive regulation of mononuclear cell proliferation is_a: GO:0050670 ! regulation of lymphocyte proliferation is_a: GO:0051251 ! positive regulation of lymphocyte activation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0046651 ! positively regulates lymphocyte proliferation relationship: RO:0002213 GO:0046651 ! positively regulates lymphocyte proliferation [Term] id: GO:0050672 name: negative regulation of lymphocyte proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of lymphocyte proliferation." [GOC:ai] synonym: "down regulation of lymphocyte proliferation" EXACT [] synonym: "down-regulation of lymphocyte proliferation" EXACT [] synonym: "downregulation of lymphocyte proliferation" EXACT [] is_a: GO:0032945 ! negative regulation of mononuclear cell proliferation is_a: GO:0050670 ! regulation of lymphocyte proliferation is_a: GO:0051250 ! negative regulation of lymphocyte activation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0046651 ! negatively regulates lymphocyte proliferation relationship: RO:0002212 GO:0046651 ! negatively regulates lymphocyte proliferation [Term] id: GO:0050673 name: epithelial cell proliferation namespace: biological_process def: "The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population. Epithelial cells make up the epithelium, the covering of internal and external surfaces of the body, including the lining of vessels and other small cavities. It consists of cells joined by small amounts of cementing substances." [ISBN:0721662544] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000066 ! acts on population of epithelial cell relationship: RO:0012003 CL:0000066 ! acts on population of epithelial cell [Term] id: GO:0050678 name: regulation of epithelial cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of epithelial cell proliferation." [GOC:ai] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0050673 ! regulates (processual) epithelial cell proliferation relationship: RO:0002211 GO:0050673 ! regulates (processual) epithelial cell proliferation [Term] id: GO:0050679 name: positive regulation of epithelial cell proliferation namespace: biological_process def: "Any process that activates or increases the rate or extent of epithelial cell proliferation." [GOC:ai] synonym: "up regulation of epithelial cell proliferation" EXACT [] synonym: "up-regulation of epithelial cell proliferation" EXACT [] synonym: "upregulation of epithelial cell proliferation" EXACT [] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0050678 ! regulation of epithelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0050673 ! positively regulates epithelial cell proliferation relationship: RO:0002213 GO:0050673 ! positively regulates epithelial cell proliferation [Term] id: GO:0050680 name: negative regulation of epithelial cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation." [GOC:ai] synonym: "down regulation of epithelial cell proliferation" EXACT [] synonym: "down-regulation of epithelial cell proliferation" EXACT [] synonym: "downregulation of epithelial cell proliferation" EXACT [] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0050678 ! regulation of epithelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0050673 ! negatively regulates epithelial cell proliferation relationship: RO:0002212 GO:0050673 ! negatively regulates epithelial cell proliferation [Term] id: GO:0050708 name: regulation of protein secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell." [GOC:ai] is_a: GO:0051223 ! regulation of protein transport is_a: GO:1903530 ! regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0009306 ! regulates (processual) protein secretion relationship: RO:0002211 GO:0009306 ! regulates (processual) protein secretion [Term] id: GO:0050709 name: negative regulation of protein secretion namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell." [GOC:ai] synonym: "down regulation of protein secretion" EXACT [] synonym: "down-regulation of protein secretion" EXACT [] synonym: "downregulation of protein secretion" EXACT [] is_a: GO:0050708 ! regulation of protein secretion is_a: GO:0051224 ! negative regulation of protein transport is_a: GO:1903531 ! negative regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0009306 ! negatively regulates protein secretion relationship: RO:0002212 GO:0009306 ! negatively regulates protein secretion [Term] id: GO:0050714 name: positive regulation of protein secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell." [GOC:ai] synonym: "up regulation of protein secretion" EXACT [] synonym: "up-regulation of protein secretion" EXACT [] synonym: "upregulation of protein secretion" EXACT [] is_a: GO:0050708 ! regulation of protein secretion is_a: GO:0051222 ! positive regulation of protein transport is_a: GO:1903532 ! positive regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0009306 ! positively regulates protein secretion relationship: RO:0002213 GO:0009306 ! positively regulates protein secretion [Term] id: GO:0050727 name: regulation of inflammatory response namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents." [GOC:ai] is_a: GO:0031347 ! regulation of defense response is_a: GO:0032101 ! regulation of response to external stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006954 ! regulates (processual) inflammatory response relationship: RO:0002211 GO:0006954 ! regulates (processual) inflammatory response [Term] id: GO:0050728 name: negative regulation of inflammatory response namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response." [GOC:ai] synonym: "anti-inflammatory response" EXACT [] synonym: "down regulation of inflammatory response" EXACT [] synonym: "down-regulation of inflammatory response" EXACT [] synonym: "downregulation of inflammatory response" EXACT [] is_a: GO:0031348 ! negative regulation of defense response is_a: GO:0032102 ! negative regulation of response to external stimulus is_a: GO:0050727 ! regulation of inflammatory response intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006954 ! negatively regulates inflammatory response relationship: RO:0002212 GO:0006954 ! negatively regulates inflammatory response [Term] id: GO:0050729 name: positive regulation of inflammatory response namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the inflammatory response." [GOC:ai] synonym: "up regulation of inflammatory response" EXACT [] synonym: "up-regulation of inflammatory response" EXACT [] synonym: "upregulation of inflammatory response" EXACT [] is_a: GO:0031349 ! positive regulation of defense response is_a: GO:0032103 ! positive regulation of response to external stimulus is_a: GO:0050727 ! regulation of inflammatory response intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006954 ! positively regulates inflammatory response relationship: RO:0002213 GO:0006954 ! positively regulates inflammatory response [Term] id: GO:0050764 name: regulation of phagocytosis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of phagocytosis, the process in which phagocytes engulf external particulate material." [GOC:ai] is_a: GO:0030100 ! regulation of endocytosis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006909 ! regulates (processual) phagocytosis relationship: RO:0002211 GO:0006909 ! regulates (processual) phagocytosis [Term] id: GO:0050765 name: negative regulation of phagocytosis namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of phagocytosis." [GOC:ai] synonym: "down regulation of phagocytosis" EXACT [] synonym: "down-regulation of phagocytosis" EXACT [] synonym: "downregulation of phagocytosis" EXACT [] is_a: GO:0045806 ! negative regulation of endocytosis is_a: GO:0050764 ! regulation of phagocytosis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006909 ! negatively regulates phagocytosis relationship: RO:0002212 GO:0006909 ! negatively regulates phagocytosis [Term] id: GO:0050766 name: positive regulation of phagocytosis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of phagocytosis." [GOC:ai] synonym: "up regulation of phagocytosis" EXACT [] synonym: "up-regulation of phagocytosis" EXACT [] synonym: "upregulation of phagocytosis" EXACT [] is_a: GO:0045807 ! positive regulation of endocytosis is_a: GO:0050764 ! regulation of phagocytosis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006909 ! positively regulates phagocytosis relationship: RO:0002213 GO:0006909 ! positively regulates phagocytosis [Term] id: GO:0050767 name: regulation of neurogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of neurogenesis, the generation of cells in the nervous system." [GOC:ai] is_a: GO:0051960 ! regulation of nervous system development is_a: GO:0060284 ! regulation of cell development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0022008 ! regulates (processual) neurogenesis relationship: RO:0002211 GO:0022008 ! regulates (processual) neurogenesis [Term] id: GO:0050768 name: negative regulation of neurogenesis namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system." [GOC:ai] synonym: "down regulation of neurogenesis" EXACT [] synonym: "down-regulation of neurogenesis" EXACT [] synonym: "downregulation of neurogenesis" EXACT [] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0050767 ! regulation of neurogenesis is_a: GO:0051961 ! negative regulation of nervous system development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0022008 ! negatively regulates neurogenesis relationship: RO:0002212 GO:0022008 ! negatively regulates neurogenesis [Term] id: GO:0050769 name: positive regulation of neurogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system." [GOC:ai] synonym: "up regulation of neurogenesis" EXACT [] synonym: "up-regulation of neurogenesis" EXACT [] synonym: "upregulation of neurogenesis" EXACT [] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0050767 ! regulation of neurogenesis is_a: GO:0051962 ! positive regulation of nervous system development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0022008 ! positively regulates neurogenesis relationship: RO:0002213 GO:0022008 ! positively regulates neurogenesis [Term] id: GO:0050776 name: regulation of immune response namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus." [GOC:ai] is_a: GO:0002682 ! regulation of immune system process is_a: GO:0048583 ! regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006955 ! regulates (processual) immune response relationship: RO:0002211 GO:0006955 ! regulates (processual) immune response [Term] id: GO:0050777 name: negative regulation of immune response namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus." [GOC:ai] synonym: "down regulation of immune response" EXACT [] synonym: "down-regulation of immune response" EXACT [] synonym: "downregulation of immune response" EXACT [] is_a: GO:0002683 ! negative regulation of immune system process is_a: GO:0048585 ! negative regulation of response to stimulus is_a: GO:0050776 ! regulation of immune response intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006955 ! negatively regulates immune response relationship: RO:0002212 GO:0006955 ! negatively regulates immune response [Term] id: GO:0050778 name: positive regulation of immune response namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus." [GOC:ai] synonym: "up regulation of immune response" EXACT [] synonym: "up-regulation of immune response" EXACT [] synonym: "upregulation of immune response" EXACT [] is_a: GO:0002684 ! positive regulation of immune system process is_a: GO:0048584 ! positive regulation of response to stimulus is_a: GO:0050776 ! regulation of immune response intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006955 ! positively regulates immune response relationship: RO:0002213 GO:0006955 ! positively regulates immune response [Term] id: GO:0050789 name: regulation of biological process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule." [GOC:ai, GOC:go_curators] synonym: "regulation of physiological process" EXACT [] is_a: GO:0065007 ! biological regulation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0008150 ! regulates (processual) biological_process relationship: RO:0002211 GO:0008150 ! regulates (processual) biological_process [Term] id: GO:0050790 name: regulation of catalytic activity namespace: biological_process def: "Any process that modulates the activity of an enzyme." [GOC:ai, GOC:ebc, GOC:vw] synonym: "regulation of enzyme activity" EXACT [] is_a: GO:0065009 ! regulation of molecular function intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003824 ! regulates (processual) catalytic activity relationship: RO:0002211 GO:0003824 ! regulates (processual) catalytic activity [Term] id: GO:0050793 name: regulation of developmental process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." [GOC:go_curators] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0032502 ! regulates (processual) developmental process relationship: RO:0002211 GO:0032502 ! regulates (processual) developmental process [Term] id: GO:0050794 name: regulation of cellular process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:go_curators] synonym: "regulation of cellular physiological process" EXACT [] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0009987 ! regulates (processual) cellular process relationship: RO:0002211 GO:0009987 ! regulates (processual) cellular process [Term] id: GO:0050795 name: regulation of behavior namespace: biological_process def: "Any process that modulates the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli." [GOC:go_curators, GOC:pr] synonym: "regulation of behaviour" EXACT [] is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007610 ! regulates (processual) behavior relationship: RO:0002211 GO:0007610 ! regulates (processual) behavior [Term] id: GO:0050796 name: regulation of insulin secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of insulin." [GOC:ai] is_a: GO:0050708 ! regulation of protein secretion is_a: GO:0090276 ! regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030073 ! regulates (processual) insulin secretion relationship: RO:0002211 GO:0030073 ! regulates (processual) insulin secretion [Term] id: GO:0050803 name: regulation of synapse structure or activity namespace: biological_process def: "Any process that modulates the physical form or the activity of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell)." [GOC:ai] relationship: RO:0002160 NCBITaxon:6072 ! only in taxon Eumetazoa relationship: RO:0002162 NCBITaxon:6072 {all_only="true"} ! in taxon Eumetazoa [Term] id: GO:0050804 name: modulation of chemical synaptic transmission namespace: biological_process def: "Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission." [GOC:ai] synonym: "regulation of chemical synaptic transmission" EXACT [] synonym: "regulation of synaptic transmission" EXACT [] is_a: GO:0099177 ! regulation of trans-synaptic signaling intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007268 ! regulates (processual) chemical synaptic transmission relationship: RO:0002211 GO:0007268 ! regulates (processual) chemical synaptic transmission [Term] id: GO:0050805 name: negative regulation of synaptic transmission namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse." [GOC:ai] synonym: "down regulation of synaptic transmission" EXACT [] synonym: "down-regulation of synaptic transmission" EXACT [] synonym: "downregulation of synaptic transmission" EXACT [] is_a: GO:0010648 ! negative regulation of cell communication is_a: GO:0023057 ! negative regulation of signaling is_a: GO:0050804 ! modulation of chemical synaptic transmission intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007268 ! negatively regulates chemical synaptic transmission relationship: RO:0002212 GO:0007268 ! negatively regulates chemical synaptic transmission [Term] id: GO:0050806 name: positive regulation of synaptic transmission namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse." [GOC:ai] synonym: "up regulation of synaptic transmission" EXACT [] synonym: "up-regulation of synaptic transmission" EXACT [] synonym: "upregulation of synaptic transmission" EXACT [] is_a: GO:0010647 ! positive regulation of cell communication is_a: GO:0023056 ! positive regulation of signaling is_a: GO:0050804 ! modulation of chemical synaptic transmission intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007268 ! positively regulates chemical synaptic transmission relationship: RO:0002213 GO:0007268 ! positively regulates chemical synaptic transmission [Term] id: GO:0050807 name: regulation of synapse organization namespace: biological_process def: "Any process that modulates the physical form of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell)." [GOC:ai, GOC:dph, GOC:tb] synonym: "regulation of synapse organisation" EXACT [GOC:mah] synonym: "regulation of synapse structure" EXACT [] is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0050808 ! regulates (processual) synapse organization relationship: BFO:0000050 GO:0050803 ! part of regulation of synapse structure or activity relationship: RO:0002211 GO:0050808 ! regulates (processual) synapse organization [Term] id: GO:0050808 name: synapse organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell)." [GOC:ai, GOC:pr] synonym: "synapse organisation" EXACT [] is_a: GO:0034330 ! cell junction organization intersection_of: GO:0009987 ! cellular process intersection_of: RO:0002592 GO:0045202 ! results in organization of synapse relationship: RO:0002592 GO:0045202 ! results in organization of synapse [Term] id: GO:0050810 name: regulation of steroid biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus." [GOC:ai] synonym: "regulation of steroid anabolism" EXACT [] synonym: "regulation of steroid biosynthesis" EXACT [] synonym: "regulation of steroid formation" EXACT [] synonym: "regulation of steroid synthesis" EXACT [] synonym: "regulation of steroidogenesis" EXACT [] is_a: GO:0019218 ! regulation of steroid metabolic process is_a: GO:0046890 ! regulation of lipid biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006694 ! regulates (processual) steroid biosynthetic process relationship: RO:0002211 GO:0006694 ! regulates (processual) steroid biosynthetic process [Term] id: GO:0050832 name: defense response to fungus namespace: biological_process def: "Reactions triggered in response to the presence of a fungus that act to protect the cell or organism." [GOC:ai] synonym: "defence response to fungi" EXACT [] synonym: "defence response to fungus" EXACT [] synonym: "defense response to fungi" EXACT [] is_a: GO:0009620 ! response to fungus is_a: GO:0098542 ! defense response to other organism intersection_of: GO:0006952 ! defense response intersection_of: RO:0004009 NCBITaxon:4751 ! has primary input Fungi [Term] id: GO:0050863 name: regulation of T cell activation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of T cell activation." [GOC:ai] synonym: "regulation of T lymphocyte activation" EXACT [] synonym: "regulation of T-cell activation" EXACT [] synonym: "regulation of T-lymphocyte activation" EXACT [] is_a: GO:0051249 ! regulation of lymphocyte activation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0042110 ! regulates (processual) T cell activation relationship: RO:0002211 GO:0042110 ! regulates (processual) T cell activation [Term] id: GO:0050865 name: regulation of cell activation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand." [GOC:ai] is_a: GO:0050794 ! regulation of cellular process is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001775 ! regulates (processual) cell activation relationship: RO:0002211 GO:0001775 ! regulates (processual) cell activation [Term] id: GO:0050866 name: negative regulation of cell activation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell activation." [GOC:ai] synonym: "down regulation of cell activation" EXACT [] synonym: "down-regulation of cell activation" EXACT [] synonym: "downregulation of cell activation" EXACT [] is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:0050865 ! regulation of cell activation is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001775 ! negatively regulates cell activation relationship: RO:0002212 GO:0001775 ! negatively regulates cell activation [Term] id: GO:0050867 name: positive regulation of cell activation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of activation." [GOC:ai] synonym: "up regulation of cell activation" EXACT [] synonym: "up-regulation of cell activation" EXACT [] synonym: "upregulation of cell activation" EXACT [] is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:0050865 ! regulation of cell activation is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001775 ! positively regulates cell activation relationship: RO:0002213 GO:0001775 ! positively regulates cell activation [Term] id: GO:0050868 name: negative regulation of T cell activation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of T cell activation." [GOC:ai] synonym: "down regulation of T cell activation" EXACT [] synonym: "down-regulation of T cell activation" EXACT [] synonym: "downregulation of T cell activation" EXACT [] synonym: "negative regulation of T lymphocyte activation" EXACT [] synonym: "negative regulation of T-cell activation" EXACT [] synonym: "negative regulation of T-lymphocyte activation" EXACT [] is_a: GO:0050863 ! regulation of T cell activation is_a: GO:0051250 ! negative regulation of lymphocyte activation is_a: GO:1903038 ! negative regulation of leukocyte cell-cell adhesion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0042110 ! negatively regulates T cell activation relationship: RO:0002212 GO:0042110 ! negatively regulates T cell activation [Term] id: GO:0050870 name: positive regulation of T cell activation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of T cell activation." [GOC:ai] synonym: "positive regulation of T lymphocyte activation" EXACT [] synonym: "positive regulation of T-cell activation" EXACT [] synonym: "positive regulation of T-lymphocyte activation" EXACT [] synonym: "up regulation of T cell activation" EXACT [] synonym: "up-regulation of T cell activation" EXACT [] synonym: "upregulation of T cell activation" EXACT [] is_a: GO:0050863 ! regulation of T cell activation is_a: GO:0051251 ! positive regulation of lymphocyte activation is_a: GO:1903039 ! positive regulation of leukocyte cell-cell adhesion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0042110 ! positively regulates T cell activation relationship: RO:0002213 GO:0042110 ! positively regulates T cell activation [Term] id: GO:0050877 name: nervous system process namespace: biological_process def: "A organ system process carried out by any of the organs or tissues of neurological system." [GOC:ai, GOC:mtg_cardio] synonym: "neurological system process" EXACT [] synonym: "neurophysiological process" EXACT [] is_a: GO:0003008 ! system process intersection_of: GO:0003008 ! system process intersection_of: RO:0000057 UBERON:0001016 ! has participant nervous system relationship: RO:0000057 UBERON:0001016 ! has participant nervous system relationship: RO:0002160 NCBITaxon:33208 ! only in taxon Metazoa relationship: RO:0002162 NCBITaxon:33208 {all_only="true"} ! in taxon Metazoa [Term] id: GO:0050878 name: regulation of body fluid levels namespace: biological_process def: "Any process that modulates the levels of body fluids." [GOC:ai, GOC:dph, GOC:tb] [Term] id: GO:0050879 name: multicellular organismal movement namespace: biological_process def: "Any physiological process involved in changing the position of a multicellular organism or an anatomical part of a multicellular organism." [GOC:dph, GOC:mtg_muscle, GOC:tb] is_a: GO:0032501 ! multicellular organismal process [Term] id: GO:0050881 name: musculoskeletal movement namespace: biological_process def: "The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system." [GOC:dph] is_a: GO:0050879 ! multicellular organismal movement is_a: GO:0050905 ! neuromuscular process [Term] id: GO:0050886 name: endocrine process namespace: biological_process def: "The process that involves the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system." [ISBN:0721662544] synonym: "endocrine physiological process" EXACT [] synonym: "endocrine physiology" EXACT [] is_a: GO:0003008 ! system process [Term] id: GO:0050890 name: cognition namespace: biological_process def: "The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory." [ISBN:0721619908] xref: Wikipedia:Cognition is_a: GO:0050877 ! nervous system process [Term] id: GO:0050896 name: response to stimulus namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism." [GOC:ai, GOC:bf] synonym: "physiological response to stimulus" EXACT [] is_a: GO:0008150 ! biological_process [Term] id: GO:0050900 name: leukocyte migration namespace: biological_process def: "The movement of a leukocyte within or between different tissues and organs of the body." [GOC:add, ISBN:0781735149, PMID:14680625, PMID:14708592, PMID:7507411, PMID:8600538] synonym: "immune cell migration" EXACT [] synonym: "immune cell trafficking" EXACT [] synonym: "leucocyte migration" EXACT [] synonym: "leucocyte trafficking" EXACT [] synonym: "leukocyte trafficking" EXACT [] is_a: GO:0002376 ! immune system process is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000738 ! results in movement of leukocyte relationship: RO:0002160 NCBITaxon:7742 ! only in taxon Vertebrata relationship: RO:0002162 NCBITaxon:7742 {all_only="true"} ! in taxon Vertebrata relationship: RO:0002565 CL:0000738 ! results in movement of leukocyte [Term] id: GO:0050905 name: neuromuscular process namespace: biological_process def: "Any process pertaining to the functions of the nervous and muscular systems of an organism." [GOC:ai] synonym: "neuromotor process" EXACT [] synonym: "neuromuscular physiological process" EXACT [] is_a: GO:0050877 ! nervous system process [Term] id: GO:0050906 name: detection of stimulus involved in sensory perception namespace: biological_process def: "The series of events involved in sensory perception in which a sensory stimulus is received and converted into a molecular signal." [GOC:ai, GOC:dos, GOC:dph] synonym: "sensory detection of stimulus" EXACT [] synonym: "sensory perception, sensory transduction of stimulus" EXACT [] synonym: "sensory perception, stimulus detection" EXACT [] synonym: "sensory transduction" EXACT [] xref: Wikipedia:Transduction_(physiology) is_a: GO:0051606 ! detection of stimulus intersection_of: GO:0051606 ! detection of stimulus intersection_of: BFO:0000050 GO:0007600 ! part of sensory perception relationship: BFO:0000050 GO:0007600 ! part of sensory perception [Term] id: GO:0050907 name: detection of chemical stimulus involved in sensory perception namespace: biological_process def: "The series of events in which a chemical stimulus is received and converted into a molecular signal as part of sensory perception." [GOC:ai, GOC:dos] synonym: "sensory detection of chemical stimulus" EXACT [] synonym: "sensory detection of chemical stimulus during sensory perception" EXACT [] synonym: "sensory perception, sensory detection of chemical stimulus" EXACT [] synonym: "sensory perception, sensory transduction of chemical stimulus" EXACT [] synonym: "sensory transduction of chemical stimulus" EXACT [] synonym: "sensory transduction of chemical stimulus during sensory perception" EXACT [] is_a: GO:0009593 ! detection of chemical stimulus is_a: GO:0050906 ! detection of stimulus involved in sensory perception intersection_of: GO:0009593 ! detection of chemical stimulus intersection_of: BFO:0000050 GO:0007600 ! part of sensory perception relationship: BFO:0000050 GO:0007606 ! part of sensory perception of chemical stimulus [Term] id: GO:0050908 name: detection of light stimulus involved in visual perception namespace: biological_process def: "The series of events involved in visual perception in which a light stimulus is received and converted into a molecular signal." [GOC:ai, GOC:dos] synonym: "sensory detection of light during visual perception" EXACT [] synonym: "sensory detection of light stimulus during visual perception" EXACT [] synonym: "sensory transduction of light during visual perception" EXACT [] synonym: "sensory transduction of light stimulus during visual perception" EXACT [] synonym: "visual perception, detection of light stimulus" EXACT [] synonym: "visual perception, sensory transduction during perception of light" EXACT [] synonym: "visual perception, sensory transduction of light stimulus" EXACT [] is_a: GO:0009584 ! detection of visible light is_a: GO:0050962 ! detection of light stimulus involved in sensory perception intersection_of: GO:0009583 ! detection of light stimulus intersection_of: BFO:0000050 GO:0007601 ! part of visual perception relationship: BFO:0000050 GO:0007601 ! part of visual perception [Term] id: GO:0050931 name: pigment cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized features of a pigmented cell, such as a melanocyte." [GOC:dgh] synonym: "chromatophore differentiation" EXACT [] synonym: "pigmented cell differentiation" EXACT [] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000147 ! results in acquisition of features of pigment cell relationship: BFO:0000050 GO:0048066 ! part of developmental pigmentation relationship: RO:0002315 CL:0000147 ! results in acquisition of features of pigment cell [Term] id: GO:0050932 name: regulation of pigment cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of pigmented cell differentiation." [GOC:ai] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0050931 ! regulates (processual) pigment cell differentiation relationship: RO:0002211 GO:0050931 ! regulates (processual) pigment cell differentiation [Term] id: GO:0050941 name: negative regulation of pigment cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of pigment cell differentiation." [GOC:ai] synonym: "down regulation of pigment cell differentiation" EXACT [] synonym: "down-regulation of pigment cell differentiation" EXACT [] synonym: "downregulation of pigment cell differentiation" EXACT [] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0048086 ! negative regulation of developmental pigmentation is_a: GO:0050932 ! regulation of pigment cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0050931 ! negatively regulates pigment cell differentiation relationship: RO:0002212 GO:0050931 ! negatively regulates pigment cell differentiation [Term] id: GO:0050942 name: positive regulation of pigment cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of pigment cell differentiation." [GOC:ai] synonym: "up regulation of pigment cell differentiation" EXACT [] synonym: "up-regulation of pigment cell differentiation" EXACT [] synonym: "upregulation of pigment cell differentiation" EXACT [] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0048087 ! positive regulation of developmental pigmentation is_a: GO:0050932 ! regulation of pigment cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0050931 ! positively regulates pigment cell differentiation relationship: RO:0002213 GO:0050931 ! positively regulates pigment cell differentiation [Term] id: GO:0050952 name: sensory perception of electrical stimulus namespace: biological_process def: "The series of events required for an organism to receive a sensory electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." [GOC:ai] is_a: GO:0007600 ! sensory perception [Term] id: GO:0050953 name: sensory perception of light stimulus namespace: biological_process def: "The series of events required for an organism to receive a sensory light stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." [GOC:ai] is_a: GO:0007600 ! sensory perception [Term] id: GO:0050954 name: sensory perception of mechanical stimulus namespace: biological_process def: "The series of events required for an organism to receive a sensory mechanical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." [GOC:ai] synonym: "mechanosensory perception" EXACT [] synonym: "perception of mechanical stimulus" EXACT [] is_a: GO:0007600 ! sensory perception [Term] id: GO:0050956 name: electroception namespace: biological_process def: "The series of events required for an organism to receive an electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. Many fish possess an electroception sense; for example, the electric eel uses low voltage pulses of electricity for navigation and prey location." [GOC:ai, PMID:10210663, Wikipedia:Electroreception] synonym: "electroception sense" EXACT [] synonym: "electroceptive sense" EXACT [] xref: Wikipedia:Electroreception is_a: GO:0050952 ! sensory perception of electrical stimulus [Term] id: GO:0050962 name: detection of light stimulus involved in sensory perception namespace: biological_process def: "The series of events in which a light stimulus is received by a cell and converted into a molecular signal as part of the sensory perception of light." [GOC:ai, GOC:dos] synonym: "sensory detection of light stimulus" EXACT [] synonym: "sensory detection of light stimulus during sensory perception" EXACT [] synonym: "sensory perception, sensory detection of light stimulus" EXACT [] synonym: "sensory perception, sensory transduction of light stimulus" EXACT [] synonym: "sensory transduction of light stimulus" EXACT [] synonym: "sensory transduction of light stimulus during sensory perception" EXACT [] is_a: GO:0009583 ! detection of light stimulus is_a: GO:0050906 ! detection of stimulus involved in sensory perception intersection_of: GO:0009583 ! detection of light stimulus intersection_of: BFO:0000050 GO:0007600 ! part of sensory perception relationship: BFO:0000050 GO:0050953 ! part of sensory perception of light stimulus [Term] id: GO:0050963 name: detection of electrical stimulus involved in sensory perception namespace: biological_process def: "The series of events in which an electrical stimulus is received by a cell and converted into a molecular signal as part of sensory perception." [GOC:ai, GOC:dos] synonym: "sensory detection of electrical stimulus" EXACT [] synonym: "sensory detection of electrical stimulus during sensory perception" EXACT [] synonym: "sensory perception, sensory detection of electrical stimulus" EXACT [] synonym: "sensory perception, sensory transduction of electrical stimulus" EXACT [] synonym: "sensory transduction of electrical stimulus" EXACT [] synonym: "sensory transduction of electrical stimulus during sensory perception" EXACT [] is_a: GO:0050906 ! detection of stimulus involved in sensory perception is_a: GO:0050981 ! detection of electrical stimulus intersection_of: GO:0050981 ! detection of electrical stimulus intersection_of: BFO:0000050 GO:0007600 ! part of sensory perception relationship: BFO:0000050 GO:0050952 ! part of sensory perception of electrical stimulus [Term] id: GO:0050964 name: detection of electrical stimulus involved in electroception namespace: biological_process def: "The series of events that contribute to electroception in which an electrical stimulus is received and converted into a molecular signal." [GOC:ai, GOC:dos] synonym: "electroception, detection of electrical stimulus" EXACT [] synonym: "electroception, sensory detection of electrical stimulus" EXACT [] synonym: "electroception, sensory transduction" EXACT [] synonym: "electroception, sensory transduction of electrical stimulus" EXACT [] is_a: GO:0050963 ! detection of electrical stimulus involved in sensory perception intersection_of: GO:0050981 ! detection of electrical stimulus intersection_of: BFO:0000050 GO:0050956 ! part of electroception relationship: BFO:0000050 GO:0050956 ! part of electroception [Term] id: GO:0050967 name: detection of electrical stimulus involved in sensory perception of pain namespace: biological_process def: "The series of events that contribute to the perception of pain in which an electrical stimulus is received and converted into a molecular signal." [GOC:ai, GOC:dos, GOC:dph, GOC:tb] synonym: "perception of pain, detection of electrical stimulus" EXACT [] synonym: "perception of pain, sensory detection of electrical stimulus" EXACT [] synonym: "perception of pain, sensory transduction of electrical stimulus" EXACT [] is_a: GO:0050963 ! detection of electrical stimulus involved in sensory perception is_a: GO:0062149 ! detection of stimulus involved in sensory perception of pain intersection_of: GO:0050981 ! detection of electrical stimulus intersection_of: BFO:0000050 GO:0019233 ! part of sensory perception of pain [Term] id: GO:0050968 name: detection of chemical stimulus involved in sensory perception of pain namespace: biological_process def: "The series of events involved in the perception of pain in which a chemical stimulus is received and converted into a molecular signal." [GOC:ai] synonym: "perception of pain, detection of chemical stimulus" EXACT [] synonym: "perception of pain, sensory detection of chemical stimulus" EXACT [] synonym: "perception of pain, sensory transduction of chemical stimulus" EXACT [] synonym: "sensory detection of chemical stimulus during perception of pain" EXACT [] synonym: "sensory transduction of chemical stimulus during perception of pain" EXACT [] is_a: GO:0050907 ! detection of chemical stimulus involved in sensory perception is_a: GO:0062149 ! detection of stimulus involved in sensory perception of pain intersection_of: GO:0009593 ! detection of chemical stimulus intersection_of: BFO:0000050 GO:0019233 ! part of sensory perception of pain [Term] id: GO:0050975 name: sensory perception of touch namespace: biological_process def: "The series of events required for an organism to receive a touch stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. The perception of touch in animals is mediated by mechanoreceptors in the skin and mucous membranes and is the sense by which contact with objects gives evidence as to certain of their qualities. Different types of touch can be perceived (for example, light, coarse, pressure and tickling) and the stimulus may be external or internal (e.g. the feeling of a full stomach)." [GOC:ai] synonym: "perception of touch" EXACT [] synonym: "tactile sense" EXACT [] synonym: "taction" EXACT [] synonym: "tactition" EXACT [] xref: Wikipedia:Touch is_a: GO:0050954 ! sensory perception of mechanical stimulus [Term] id: GO:0050981 name: detection of electrical stimulus namespace: biological_process def: "The series of events by which an electrical stimulus is received and converted into a molecular signal." [GOC:ai, GOC:dos] is_a: GO:0009582 ! detection of abiotic stimulus is_a: GO:0051602 ! response to electrical stimulus [Term] id: GO:0050994 name: regulation of lipid catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of lipids." [GOC:ai] synonym: "regulation of lipid breakdown" EXACT [] synonym: "regulation of lipid catabolism" EXACT [] synonym: "regulation of lipid degradation" EXACT [] is_a: GO:0009894 ! regulation of catabolic process is_a: GO:0019216 ! regulation of lipid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0016042 ! regulates (processual) lipid catabolic process relationship: RO:0002211 GO:0016042 ! regulates (processual) lipid catabolic process [Term] id: GO:0050995 name: negative regulation of lipid catabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids." [GOC:ai] synonym: "down regulation of lipid catabolic process" EXACT [] synonym: "down-regulation of lipid catabolic process" EXACT [] synonym: "downregulation of lipid catabolic process" EXACT [] synonym: "negative regulation of lipid breakdown" EXACT [] synonym: "negative regulation of lipid catabolism" EXACT [] synonym: "negative regulation of lipid degradation" EXACT [] is_a: GO:0009895 ! negative regulation of catabolic process is_a: GO:0045833 ! negative regulation of lipid metabolic process is_a: GO:0050994 ! regulation of lipid catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0016042 ! negatively regulates lipid catabolic process relationship: RO:0002212 GO:0016042 ! negatively regulates lipid catabolic process [Term] id: GO:0050996 name: positive regulation of lipid catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids." [GOC:ai] synonym: "positive regulation of lipid breakdown" EXACT [] synonym: "positive regulation of lipid catabolism" EXACT [] synonym: "positive regulation of lipid degradation" EXACT [] synonym: "up regulation of lipid catabolic process" EXACT [] synonym: "up-regulation of lipid catabolic process" EXACT [] synonym: "upregulation of lipid catabolic process" EXACT [] is_a: GO:0009896 ! positive regulation of catabolic process is_a: GO:0045834 ! positive regulation of lipid metabolic process is_a: GO:0050994 ! regulation of lipid catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0016042 ! positively regulates lipid catabolic process relationship: RO:0002213 GO:0016042 ! positively regulates lipid catabolic process [Term] id: GO:0051017 name: actin filament bundle assembly namespace: biological_process def: "The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness." [GOC:ai] is_a: GO:0022607 ! cellular component assembly is_a: GO:0061572 ! actin filament bundle organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0032432 ! results in assembly of actin filament bundle relationship: RO:0002588 GO:0032432 ! results in assembly of actin filament bundle [Term] id: GO:0051027 name: DNA transport namespace: biological_process def: "The directed movement of RNA, deoxyribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] is_a: GO:0050657 ! nucleic acid transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:16991 ! has primary input deoxyribonucleic acid relationship: RO:0004009 CHEBI:16991 ! has primary input deoxyribonucleic acid [Term] id: GO:0051032 name: nucleic acid transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of nucleic acids from one side of a membrane to the other. Nucleic acids are single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information." [GOC:ai] is_a: GO:0015932 ! nucleobase-containing compound transmembrane transporter activity is_a: GO:0022884 ! macromolecule transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:33696 ! has primary input nucleic acid relationship: BFO:0000050 GO:0050657 ! part of nucleic acid transport relationship: RO:0004009 CHEBI:33696 ! has primary input nucleic acid [Term] id: GO:0051033 name: RNA transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of RNA, ribonucleic acid, from one side of a membrane to the other." [GOC:ai] xref: Reactome:R-HSA-203906 "Exportin complex translocates pre-miRNA to cytosol" is_a: GO:0051032 ! nucleic acid transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:33697 ! has primary input ribonucleic acid relationship: BFO:0000050 GO:0050658 ! part of RNA transport relationship: RO:0004009 CHEBI:33697 ! has primary input ribonucleic acid [Term] id: GO:0051035 name: DNA transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of DNA, deoxyribonucleic acid, from one side of a membrane to the other." [GOC:ai] is_a: GO:0051032 ! nucleic acid transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:16991 ! has primary input deoxyribonucleic acid relationship: BFO:0000050 GO:0051027 ! part of DNA transport relationship: RO:0004009 CHEBI:16991 ! has primary input deoxyribonucleic acid [Term] id: GO:0051046 name: regulation of secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue." [GOC:ai] is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0046903 ! regulates (processual) secretion relationship: RO:0002211 GO:0046903 ! regulates (processual) secretion [Term] id: GO:0051047 name: positive regulation of secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the controlled release of a substance from a cell or a tissue." [GOC:ai] synonym: "up regulation of secretion" EXACT [] synonym: "up-regulation of secretion" EXACT [] synonym: "upregulation of secretion" EXACT [] is_a: GO:0051046 ! regulation of secretion is_a: GO:0051050 ! positive regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0046903 ! positively regulates secretion relationship: RO:0002213 GO:0046903 ! positively regulates secretion [Term] id: GO:0051048 name: negative regulation of secretion namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a substance from a cell or a tissue." [GOC:ai] synonym: "down regulation of secretion" EXACT [] synonym: "down-regulation of secretion" EXACT [] synonym: "downregulation of secretion" EXACT [] is_a: GO:0051046 ! regulation of secretion is_a: GO:0051051 ! negative regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0046903 ! negatively regulates secretion relationship: RO:0002212 GO:0046903 ! negatively regulates secretion [Term] id: GO:0051049 name: regulation of transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] is_a: GO:0032879 ! regulation of localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006810 ! regulates (processual) transport relationship: RO:0002211 GO:0006810 ! regulates (processual) transport [Term] id: GO:0051050 name: positive regulation of transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "up regulation of transport" EXACT [] synonym: "up-regulation of transport" EXACT [] synonym: "upregulation of transport" EXACT [] is_a: GO:0048518 ! positive regulation of biological process is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006810 ! positively regulates transport relationship: RO:0002213 GO:0006810 ! positively regulates transport [Term] id: GO:0051051 name: negative regulation of transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "down regulation of transport" EXACT [] synonym: "down-regulation of transport" EXACT [] synonym: "downregulation of transport" EXACT [] is_a: GO:0048519 ! negative regulation of biological process is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006810 ! negatively regulates transport relationship: RO:0002212 GO:0006810 ! negatively regulates transport [Term] id: GO:0051052 name: regulation of DNA metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA." [GOC:ai] synonym: "regulation of DNA metabolism" EXACT [] is_a: GO:0019219 ! regulation of nucleobase-containing compound metabolic process is_a: GO:0060255 ! regulation of macromolecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006259 ! regulates (processual) DNA metabolic process relationship: RO:0002211 GO:0006259 ! regulates (processual) DNA metabolic process [Term] id: GO:0051053 name: negative regulation of DNA metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA." [GOC:ai] synonym: "down regulation of DNA metabolic process" EXACT [] synonym: "down-regulation of DNA metabolic process" EXACT [] synonym: "downregulation of DNA metabolic process" EXACT [] synonym: "negative regulation of DNA metabolism" EXACT [] is_a: GO:0010605 ! negative regulation of macromolecule metabolic process is_a: GO:0045934 ! negative regulation of nucleobase-containing compound metabolic process is_a: GO:0051052 ! regulation of DNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006259 ! negatively regulates DNA metabolic process relationship: RO:0002212 GO:0006259 ! negatively regulates DNA metabolic process [Term] id: GO:0051054 name: positive regulation of DNA metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA." [GOC:ai] synonym: "positive regulation of DNA metabolism" EXACT [] synonym: "up regulation of DNA metabolic process" EXACT [] synonym: "up-regulation of DNA metabolic process" EXACT [] synonym: "upregulation of DNA metabolic process" EXACT [] is_a: GO:0010604 ! positive regulation of macromolecule metabolic process is_a: GO:0045935 ! positive regulation of nucleobase-containing compound metabolic process is_a: GO:0051052 ! regulation of DNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006259 ! positively regulates DNA metabolic process relationship: RO:0002213 GO:0006259 ! positively regulates DNA metabolic process [Term] id: GO:0051055 name: negative regulation of lipid biosynthetic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids." [GOC:ai] synonym: "down regulation of lipid biosynthetic process" EXACT [] synonym: "down-regulation of lipid biosynthetic process" EXACT [] synonym: "downregulation of lipid biosynthetic process" EXACT [] synonym: "negative regulation of lipid anabolism" EXACT [] synonym: "negative regulation of lipid biosynthesis" EXACT [] synonym: "negative regulation of lipid formation" EXACT [] synonym: "negative regulation of lipid synthesis" EXACT [] synonym: "negative regulation of lipogenesis" EXACT [GOC:sl] is_a: GO:0009890 ! negative regulation of biosynthetic process is_a: GO:0045833 ! negative regulation of lipid metabolic process is_a: GO:0046890 ! regulation of lipid biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0008610 ! negatively regulates lipid biosynthetic process relationship: RO:0002212 GO:0008610 ! negatively regulates lipid biosynthetic process [Term] id: GO:0051078 name: meiotic nuclear membrane disassembly namespace: biological_process def: "The cell cycle process in which the controlled breakdown of the nuclear membranes during meiotic cell division occurs." [GOC:bf] is_a: GO:0051081 ! nuclear membrane disassembly is_a: GO:1903046 ! meiotic cell cycle process intersection_of: GO:0051081 ! nuclear membrane disassembly intersection_of: BFO:0000050 GO:0051321 ! part of meiotic cell cycle [Term] id: GO:0051080 name: meiosis II nuclear membrane disassembly namespace: biological_process def: "The controlled breakdown of the nuclear membranes during the second division of meiosis." [GOC:bf] is_a: GO:0051078 ! meiotic nuclear membrane disassembly intersection_of: GO:0051081 ! nuclear membrane disassembly intersection_of: BFO:0000050 GO:0007135 ! part of meiosis II relationship: BFO:0000050 GO:0007135 ! part of meiosis II [Term] id: GO:0051081 name: nuclear membrane disassembly namespace: biological_process def: "The controlled breakdown of the nuclear membranes, for example during cellular division." [GOC:ai] is_a: GO:0030397 ! membrane disassembly is_a: GO:0071763 ! nuclear membrane organization intersection_of: GO:0022411 ! cellular component disassembly intersection_of: RO:0002590 GO:0031965 ! results in disassembly of nuclear membrane relationship: RO:0002590 GO:0031965 ! results in disassembly of nuclear membrane [Term] id: GO:0051093 name: negative regulation of developmental process namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." [GOC:ai] synonym: "down regulation of developmental process" EXACT [] synonym: "down-regulation of developmental process" EXACT [] synonym: "downregulation of developmental process" EXACT [] is_a: GO:0048519 ! negative regulation of biological process is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0032502 ! negatively regulates developmental process relationship: RO:0002212 GO:0032502 ! negatively regulates developmental process [Term] id: GO:0051094 name: positive regulation of developmental process namespace: biological_process def: "Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." [GOC:ai] synonym: "up regulation of developmental process" EXACT [] synonym: "up-regulation of developmental process" EXACT [] synonym: "upregulation of developmental process" EXACT [] is_a: GO:0048518 ! positive regulation of biological process is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0032502 ! positively regulates developmental process relationship: RO:0002213 GO:0032502 ! positively regulates developmental process [Term] id: GO:0051119 name: sugar transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of a sugar from one side of a membrane to the other. A sugar is any member of a class of sweet, water-soluble, crystallizable carbohydrates, which are the monosaccharides and smaller oligosaccharides." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] xref: Reactome:R-HSA-428779 "GLUT7 and GLUT11 transport glucose and fructose" xref: Reactome:R-HSA-8875902 "SLC45A3 transports Glc from extracellular region to cytosol" xref: Reactome:R-HSA-8876319 "SLC50A1 transports Glc from cytosol to extracellular region" is_a: GO:0015144 ! carbohydrate transmembrane transporter activity [Term] id: GO:0051128 name: regulation of cellular component organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." [GOC:ai] synonym: "regulation of cellular component organisation" EXACT [] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0016043 ! regulates (processual) cellular component organization relationship: RO:0002211 GO:0016043 ! regulates (processual) cellular component organization [Term] id: GO:0051129 name: negative regulation of cellular component organization namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." [GOC:ai] synonym: "down regulation of cell organization" EXACT [] synonym: "down-regulation of cell organization" EXACT [] synonym: "downregulation of cell organization" EXACT [] is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0016043 ! negatively regulates cellular component organization relationship: RO:0002212 GO:0016043 ! negatively regulates cellular component organization [Term] id: GO:0051130 name: positive regulation of cellular component organization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." [GOC:ai] synonym: "positive regulation of cell organisation" EXACT [] synonym: "up regulation of cell organization" EXACT [] synonym: "up-regulation of cell organization" EXACT [] synonym: "upregulation of cell organization" EXACT [] is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0016043 ! positively regulates cellular component organization relationship: RO:0002213 GO:0016043 ! positively regulates cellular component organization [Term] id: GO:0051145 name: smooth muscle cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary." [CL:0000192, GOC:ai] synonym: "nonstriated muscle cell differentiation" EXACT [] is_a: GO:0042692 ! muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000192 ! results in acquisition of features of smooth muscle cell relationship: RO:0002315 CL:0000192 ! results in acquisition of features of smooth muscle cell [Term] id: GO:0051146 name: striated muscle cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a striated muscle cell; striated muscle fibers are divided by transverse bands into striations, and cardiac and voluntary muscle are types of striated muscle." [CL:0000737, GOC:ai] is_a: GO:0042692 ! muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000737 ! results in acquisition of features of striated muscle cell relationship: RO:0002315 CL:0000737 ! results in acquisition of features of striated muscle cell [Term] id: GO:0051147 name: regulation of muscle cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of muscle cell differentiation." [CL:0000187, GOC:ai] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0042692 ! regulates (processual) muscle cell differentiation relationship: RO:0002211 GO:0042692 ! regulates (processual) muscle cell differentiation [Term] id: GO:0051148 name: negative regulation of muscle cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of muscle cell differentiation." [CL:0000187, GOC:ai] synonym: "down regulation of muscle cell differentiation" EXACT [] synonym: "down-regulation of muscle cell differentiation" EXACT [] synonym: "downregulation of muscle cell differentiation" EXACT [] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0051147 ! regulation of muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0042692 ! negatively regulates muscle cell differentiation relationship: RO:0002212 GO:0042692 ! negatively regulates muscle cell differentiation [Term] id: GO:0051149 name: positive regulation of muscle cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of muscle cell differentiation." [CL:0000187, GOC:ai] synonym: "up regulation of muscle cell differentiation" EXACT [] synonym: "up-regulation of muscle cell differentiation" EXACT [] synonym: "upregulation of muscle cell differentiation" EXACT [] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0051147 ! regulation of muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0042692 ! positively regulates muscle cell differentiation relationship: RO:0002213 GO:0042692 ! positively regulates muscle cell differentiation [Term] id: GO:0051150 name: regulation of smooth muscle cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of smooth muscle cell differentiation." [CL:0000192, GOC:ai] is_a: GO:0051147 ! regulation of muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0051145 ! regulates (processual) smooth muscle cell differentiation relationship: RO:0002211 GO:0051145 ! regulates (processual) smooth muscle cell differentiation [Term] id: GO:0051151 name: negative regulation of smooth muscle cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell differentiation." [CL:0000192, GOC:ai] synonym: "down regulation of smooth muscle cell differentiation" EXACT [] synonym: "down-regulation of smooth muscle cell differentiation" EXACT [] synonym: "downregulation of smooth muscle cell differentiation" EXACT [] is_a: GO:0051148 ! negative regulation of muscle cell differentiation is_a: GO:0051150 ! regulation of smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0051145 ! negatively regulates smooth muscle cell differentiation relationship: RO:0002212 GO:0051145 ! negatively regulates smooth muscle cell differentiation [Term] id: GO:0051152 name: positive regulation of smooth muscle cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of smooth muscle cell differentiation." [CL:0000192, GOC:ai] synonym: "up regulation of smooth muscle cell differentiation" EXACT [] synonym: "up-regulation of smooth muscle cell differentiation" EXACT [] synonym: "upregulation of smooth muscle cell differentiation" EXACT [] is_a: GO:0051149 ! positive regulation of muscle cell differentiation is_a: GO:0051150 ! regulation of smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0051145 ! positively regulates smooth muscle cell differentiation relationship: RO:0002213 GO:0051145 ! positively regulates smooth muscle cell differentiation [Term] id: GO:0051153 name: regulation of striated muscle cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of striated muscle cell differentiation." [CL:0000737, GOC:ai] is_a: GO:0051147 ! regulation of muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0051146 ! regulates (processual) striated muscle cell differentiation relationship: RO:0002211 GO:0051146 ! regulates (processual) striated muscle cell differentiation [Term] id: GO:0051154 name: negative regulation of striated muscle cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle cell differentiation." [CL:0000737, GOC:ai] synonym: "down regulation of striated muscle cell differentiation" EXACT [] synonym: "down-regulation of striated muscle cell differentiation" EXACT [] synonym: "downregulation of striated muscle cell differentiation" EXACT [] is_a: GO:0051148 ! negative regulation of muscle cell differentiation is_a: GO:0051153 ! regulation of striated muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0051146 ! negatively regulates striated muscle cell differentiation relationship: RO:0002212 GO:0051146 ! negatively regulates striated muscle cell differentiation [Term] id: GO:0051155 name: positive regulation of striated muscle cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of striated muscle cell differentiation." [CL:0000737, GOC:ai] synonym: "up regulation of striated muscle cell differentiation" EXACT [] synonym: "up-regulation of striated muscle cell differentiation" EXACT [] synonym: "upregulation of striated muscle cell differentiation" EXACT [] is_a: GO:0051149 ! positive regulation of muscle cell differentiation is_a: GO:0051153 ! regulation of striated muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0051146 ! positively regulates striated muscle cell differentiation relationship: RO:0002213 GO:0051146 ! positively regulates striated muscle cell differentiation [Term] id: GO:0051169 name: nuclear transport namespace: biological_process def: "The directed movement of substances into, out of, or within the nucleus." [GOC:ai] synonym: "nucleus transport" EXACT [] xref: Wikipedia:Nuclear_transport is_a: GO:0046907 ! intracellular transport intersection_of: GO:0006810 ! transport intersection_of: BFO:0000066 GO:0005622 ! occurs in intracellular anatomical structure intersection_of: RO:0002344 GO:0005634 ! results in transport to from or in nucleus relationship: RO:0002344 GO:0005634 ! results in transport to from or in nucleus [Term] id: GO:0051171 name: regulation of nitrogen compound metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds." [GOC:ai, GOC:tb] synonym: "regulation of nitrogen metabolic process" EXACT [GOC:tb] synonym: "regulation of nitrogen metabolism" EXACT [] is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006807 ! regulates (processual) nitrogen compound metabolic process relationship: RO:0002211 GO:0006807 ! regulates (processual) nitrogen compound metabolic process [Term] id: GO:0051172 name: negative regulation of nitrogen compound metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds." [GOC:ai, GOC:tb] synonym: "down regulation of nitrogen metabolic process" EXACT [] synonym: "down-regulation of nitrogen metabolic process" EXACT [] synonym: "downregulation of nitrogen metabolic process" EXACT [] synonym: "negative regulation of nitrogen metabolic process" EXACT [GOC:tb] synonym: "negative regulation of nitrogen metabolism" EXACT [] is_a: GO:0009892 ! negative regulation of metabolic process is_a: GO:0051171 ! regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006807 ! negatively regulates nitrogen compound metabolic process relationship: RO:0002212 GO:0006807 ! negatively regulates nitrogen compound metabolic process [Term] id: GO:0051173 name: positive regulation of nitrogen compound metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds." [GOC:ai, GOC:tb] synonym: "positive regulation of nitrogen metabolic process" EXACT [GOC:tb] synonym: "positive regulation of nitrogen metabolism" EXACT [] synonym: "up regulation of nitrogen metabolic process" EXACT [] synonym: "up-regulation of nitrogen metabolic process" EXACT [] synonym: "upregulation of nitrogen metabolic process" EXACT [] is_a: GO:0009893 ! positive regulation of metabolic process is_a: GO:0051171 ! regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006807 ! positively regulates nitrogen compound metabolic process relationship: RO:0002213 GO:0006807 ! positively regulates nitrogen compound metabolic process [Term] id: GO:0051174 name: regulation of phosphorus metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus." [GOC:ai] synonym: "regulation of phosphorus metabolism" EXACT [] is_a: GO:0031323 ! regulation of cellular metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006793 ! regulates (processual) phosphorus metabolic process relationship: RO:0002211 GO:0006793 ! regulates (processual) phosphorus metabolic process [Term] id: GO:0051175 name: negative regulation of sulfur metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur." [GOC:ai] synonym: "down regulation of sulfur metabolic process" EXACT [] synonym: "down-regulation of sulfur metabolic process" EXACT [] synonym: "downregulation of sulfur metabolic process" EXACT [] synonym: "negative regulation of sulfur metabolism" EXACT [] synonym: "negative regulation of sulphur metabolic process" EXACT [] synonym: "negative regulation of sulphur metabolism" EXACT [] is_a: GO:0031324 ! negative regulation of cellular metabolic process is_a: GO:0042762 ! regulation of sulfur metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006790 ! negatively regulates sulfur compound metabolic process relationship: RO:0002212 GO:0006790 ! negatively regulates sulfur compound metabolic process [Term] id: GO:0051176 name: positive regulation of sulfur metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur." [GOC:ai] synonym: "positive regulation of sulfur metabolism" EXACT [] synonym: "positive regulation of sulphur metabolic process" EXACT [] synonym: "positive regulation of sulphur metabolism" EXACT [] synonym: "up regulation of sulfur metabolic process" EXACT [] synonym: "up-regulation of sulfur metabolic process" EXACT [] synonym: "upregulation of sulfur metabolic process" EXACT [] is_a: GO:0031325 ! positive regulation of cellular metabolic process is_a: GO:0042762 ! regulation of sulfur metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006790 ! positively regulates sulfur compound metabolic process relationship: RO:0002213 GO:0006790 ! positively regulates sulfur compound metabolic process [Term] id: GO:0051179 name: localization namespace: biological_process def: "Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation." [GOC:ai, GOC:dos] synonym: "establishment and maintenance of localization" EXACT [] synonym: "establishment and maintenance of position" EXACT [] synonym: "localisation" EXACT [GOC:mah] is_a: GO:0008150 ! biological_process creation_date: 2013-12-18T13:51:04Z [Term] id: GO:0051216 name: cartilage development namespace: biological_process def: "The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." [GOC:cjm, PMID:23251424] synonym: "cartilage biogenesis" EXACT [] synonym: "cartilage biosynthesis" EXACT [] synonym: "cartilage element development" EXACT [] synonym: "cartilage formation" EXACT [] synonym: "cartilage organ development" EXACT [] synonym: "chondrogenesis" EXACT [] xref: Wikipedia:Chondrogenesis is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0007844 ! results in development of cartilage element relationship: BFO:0000050 GO:0001501 ! part of skeletal system development relationship: BFO:0000050 GO:0061448 ! part of connective tissue development relationship: RO:0002296 UBERON:0007844 ! results in development of cartilage element [Term] id: GO:0051222 name: positive regulation of protein transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "up regulation of protein transport" EXACT [] synonym: "up-regulation of protein transport" EXACT [] synonym: "upregulation of protein transport" EXACT [] is_a: GO:0051050 ! positive regulation of transport is_a: GO:0051223 ! regulation of protein transport is_a: GO:1903829 ! positive regulation of protein localization is_a: GO:1904951 ! positive regulation of establishment of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0015031 ! positively regulates protein transport relationship: RO:0002213 GO:0015031 ! positively regulates protein transport [Term] id: GO:0051223 name: regulation of protein transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] is_a: GO:0051049 ! regulation of transport is_a: GO:0070201 ! regulation of establishment of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0015031 ! regulates (processual) protein transport relationship: RO:0002211 GO:0015031 ! regulates (processual) protein transport [Term] id: GO:0051224 name: negative regulation of protein transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "down regulation of protein transport" EXACT [] synonym: "down-regulation of protein transport" EXACT [] synonym: "downregulation of protein transport" EXACT [] is_a: GO:0051051 ! negative regulation of transport is_a: GO:0051223 ! regulation of protein transport is_a: GO:1903828 ! negative regulation of protein localization is_a: GO:1904950 ! negative regulation of establishment of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0015031 ! negatively regulates protein transport relationship: RO:0002212 GO:0015031 ! negatively regulates protein transport [Term] id: GO:0051234 name: establishment of localization namespace: biological_process def: "Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation." [GOC:ai, GOC:dos] synonym: "establishment of localisation" EXACT [GOC:mah] is_a: GO:0051179 ! localization [Term] id: GO:0051236 name: establishment of RNA localization namespace: biological_process def: "The directed movement of RNA to a specific location." [GOC:ai] synonym: "establishment of RNA localisation" EXACT [GOC:mah] synonym: "RNA positioning" EXACT [] synonym: "RNA recruitment" EXACT [] is_a: GO:0051234 ! establishment of localization relationship: BFO:0000050 GO:0006403 ! part of RNA localization [Term] id: GO:0051239 name: regulation of multicellular organismal process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs." [GOC:ai, GOC:dph, GOC:tb] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0032501 ! regulates (processual) multicellular organismal process relationship: RO:0002211 GO:0032501 ! regulates (processual) multicellular organismal process [Term] id: GO:0051240 name: positive regulation of multicellular organismal process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs." [GOC:ai] synonym: "up regulation of multicellular organismal process" EXACT [] synonym: "up-regulation of multicellular organismal process" EXACT [] synonym: "upregulation of multicellular organismal process" EXACT [] is_a: GO:0048518 ! positive regulation of biological process is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0032501 ! positively regulates multicellular organismal process relationship: RO:0002213 GO:0032501 ! positively regulates multicellular organismal process [Term] id: GO:0051241 name: negative regulation of multicellular organismal process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs." [GOC:ai] synonym: "down regulation of multicellular organismal process" EXACT [] synonym: "down-regulation of multicellular organismal process" EXACT [] synonym: "downregulation of multicellular organismal process" EXACT [] is_a: GO:0048519 ! negative regulation of biological process is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0032501 ! negatively regulates multicellular organismal process relationship: RO:0002212 GO:0032501 ! negatively regulates multicellular organismal process [Term] id: GO:0051246 name: regulation of protein metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein." [GOC:ai] synonym: "regulation of protein metabolism" EXACT [] is_a: GO:0051171 ! regulation of nitrogen compound metabolic process is_a: GO:0060255 ! regulation of macromolecule metabolic process is_a: GO:0080090 ! regulation of primary metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0019538 ! regulates (processual) protein metabolic process relationship: RO:0002211 GO:0019538 ! regulates (processual) protein metabolic process [Term] id: GO:0051247 name: positive regulation of protein metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein." [GOC:ai] synonym: "positive regulation of cellular protein metabolic process" EXACT [] synonym: "positive regulation of cellular protein metabolism" EXACT [] synonym: "positive regulation of protein metabolism" EXACT [] synonym: "up regulation of cellular protein metabolic process" EXACT [] synonym: "up regulation of protein metabolic process" EXACT [] synonym: "up-regulation of cellular protein metabolic process" EXACT [] synonym: "up-regulation of protein metabolic process" EXACT [] synonym: "upregulation of cellular protein metabolic process" EXACT [] synonym: "upregulation of protein metabolic process" EXACT [] is_a: GO:0010604 ! positive regulation of macromolecule metabolic process is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process is_a: GO:0051246 ! regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0019538 ! positively regulates protein metabolic process relationship: RO:0002213 GO:0019538 ! positively regulates protein metabolic process [Term] id: GO:0051248 name: negative regulation of protein metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein." [GOC:ai] synonym: "down regulation of cellular protein metabolic process" EXACT [] synonym: "down regulation of protein metabolic process" EXACT [] synonym: "down-regulation of cellular protein metabolic process" EXACT [] synonym: "down-regulation of protein metabolic process" EXACT [] synonym: "downregulation of cellular protein metabolic process" EXACT [] synonym: "downregulation of protein metabolic process" EXACT [] synonym: "negative regulation of cellular protein metabolic process" EXACT [] synonym: "negative regulation of cellular protein metabolism" EXACT [] synonym: "negative regulation of protein metabolism" EXACT [] is_a: GO:0010605 ! negative regulation of macromolecule metabolic process is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process is_a: GO:0051246 ! regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0019538 ! negatively regulates protein metabolic process relationship: RO:0002212 GO:0019538 ! negatively regulates protein metabolic process [Term] id: GO:0051249 name: regulation of lymphocyte activation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of lymphocyte activation." [GOC:ai] is_a: GO:0002694 ! regulation of leukocyte activation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0046649 ! regulates (processual) lymphocyte activation relationship: RO:0002211 GO:0046649 ! regulates (processual) lymphocyte activation [Term] id: GO:0051250 name: negative regulation of lymphocyte activation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte activation." [GOC:ai] synonym: "down regulation of lymphocyte activation" EXACT [] synonym: "down-regulation of lymphocyte activation" EXACT [] synonym: "downregulation of lymphocyte activation" EXACT [] is_a: GO:0002695 ! negative regulation of leukocyte activation is_a: GO:0051249 ! regulation of lymphocyte activation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0046649 ! negatively regulates lymphocyte activation relationship: RO:0002212 GO:0046649 ! negatively regulates lymphocyte activation [Term] id: GO:0051251 name: positive regulation of lymphocyte activation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of lymphocyte activation." [GOC:ai] synonym: "up regulation of lymphocyte activation" EXACT [] synonym: "up-regulation of lymphocyte activation" EXACT [] synonym: "upregulation of lymphocyte activation" EXACT [] is_a: GO:0002696 ! positive regulation of leukocyte activation is_a: GO:0051249 ! regulation of lymphocyte activation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0046649 ! positively regulates lymphocyte activation relationship: RO:0002213 GO:0046649 ! positively regulates lymphocyte activation [Term] id: GO:0051252 name: regulation of RNA metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA." [GOC:ai] synonym: "regulation of RNA metabolism" EXACT [] is_a: GO:0019219 ! regulation of nucleobase-containing compound metabolic process is_a: GO:0060255 ! regulation of macromolecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0016070 ! regulates (processual) RNA metabolic process relationship: RO:0002211 GO:0016070 ! regulates (processual) RNA metabolic process [Term] id: GO:0051253 name: negative regulation of RNA metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA." [GOC:ai] synonym: "down regulation of RNA metabolic process" EXACT [] synonym: "down-regulation of RNA metabolic process" EXACT [] synonym: "downregulation of RNA metabolic process" EXACT [] synonym: "negative regulation of RNA metabolism" EXACT [] is_a: GO:0010605 ! negative regulation of macromolecule metabolic process is_a: GO:0045934 ! negative regulation of nucleobase-containing compound metabolic process is_a: GO:0051252 ! regulation of RNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0016070 ! negatively regulates RNA metabolic process relationship: RO:0002212 GO:0016070 ! negatively regulates RNA metabolic process [Term] id: GO:0051254 name: positive regulation of RNA metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving RNA." [GOC:ai] synonym: "positive regulation of RNA metabolism" EXACT [] synonym: "up regulation of RNA metabolic process" EXACT [] synonym: "up-regulation of RNA metabolic process" EXACT [] synonym: "upregulation of RNA metabolic process" EXACT [] is_a: GO:0010604 ! positive regulation of macromolecule metabolic process is_a: GO:0045935 ! positive regulation of nucleobase-containing compound metabolic process is_a: GO:0051252 ! regulation of RNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0016070 ! positively regulates RNA metabolic process relationship: RO:0002213 GO:0016070 ! positively regulates RNA metabolic process [Term] id: GO:0051258 name: protein polymerization namespace: biological_process def: "The process of creating protein polymers, compounds composed of a large number of component monomers; polymeric proteins may be made up of different or identical monomers. Polymerization occurs by the addition of extra monomers to an existing poly- or oligomeric protein." [GOC:ai] synonym: "protein polymer biosynthesis" EXACT [] synonym: "protein polymer biosynthetic process" EXACT [] synonym: "protein polymer formation" EXACT [] is_a: GO:0065003 ! protein-containing complex assembly [Term] id: GO:0051261 name: protein depolymerization namespace: biological_process def: "The process in which protein polymers, compounds composed of a large number of component monomers, are broken down. Depolymerization occurs by the successive removal of monomers from an existing poly- or oligomeric protein." [GOC:ai] synonym: "protein polymer breakdown" EXACT [] synonym: "protein polymer catabolic process" EXACT [] synonym: "protein polymer catabolism" EXACT [] synonym: "protein polymer degradation" EXACT [] is_a: GO:0032984 ! protein-containing complex disassembly [Term] id: GO:0051276 name: chromosome organization namespace: biological_process def: "A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome." [GOC:ai, GOC:dph, GOC:jl, GOC:mah] synonym: "chromosome organisation" EXACT [] synonym: "DNA condensation" EXACT [] is_a: GO:0006996 ! organelle organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0005694 ! results in organization of chromosome relationship: RO:0002592 GO:0005694 ! results in organization of chromosome [Term] id: GO:0051301 name: cell division namespace: biological_process def: "The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells." [GOC:di, GOC:go_curators, GOC:pr] xref: Wikipedia:Cell_division is_a: GO:0009987 ! cellular process [Term] id: GO:0051302 name: regulation of cell division namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells." [GOC:go_curators] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0051301 ! regulates (processual) cell division relationship: RO:0002211 GO:0051301 ! regulates (processual) cell division [Term] id: GO:0051303 name: establishment of chromosome localization namespace: biological_process def: "The directed movement of a chromosome to a specific location." [GOC:ai] synonym: "chromosome positioning" EXACT [] synonym: "establishment of chromosome localisation" EXACT [GOC:mah] is_a: GO:0050000 ! chromosome localization is_a: GO:0051649 ! establishment of localization in cell is_a: GO:0051656 ! establishment of organelle localization intersection_of: GO:0051234 ! establishment of localization intersection_of: RO:0004009 GO:0005694 ! has primary input chromosome [Term] id: GO:0051321 name: meiotic cell cycle namespace: biological_process def: "Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions." [GOC:ai] xref: Wikipedia:Meiosis is_a: GO:0007049 ! cell cycle is_a: GO:0022414 ! reproductive process intersection_of: GO:0007049 ! cell cycle intersection_of: BFO:0000051 GO:0140013 ! has part meiotic nuclear division relationship: BFO:0000050 GO:0019953 ! part of sexual reproduction relationship: BFO:0000051 GO:0140013 ! has part meiotic nuclear division relationship: RO:0002160 NCBITaxon:2759 ! only in taxon Eukaryota relationship: RO:0002162 NCBITaxon:2759 {all_only="true"} ! in taxon Eukaryota [Term] id: GO:0051336 name: regulation of hydrolase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3." [GOC:ai] synonym: "hydrolase regulator" EXACT [] is_a: GO:0050790 ! regulation of catalytic activity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0016787 ! regulates (processual) hydrolase activity relationship: RO:0002211 GO:0016787 ! regulates (processual) hydrolase activity [Term] id: GO:0051338 name: regulation of transferase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2." [GOC:ai] synonym: "transferase regulator" EXACT [] is_a: GO:0050790 ! regulation of catalytic activity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0016740 ! regulates (processual) transferase activity relationship: RO:0002211 GO:0016740 ! regulates (processual) transferase activity [Term] id: GO:0051345 name: positive regulation of hydrolase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds." [GOC:ai] synonym: "hydrolase activator" EXACT [] synonym: "up regulation of hydrolase activity" EXACT [] synonym: "up-regulation of hydrolase activity" EXACT [] synonym: "upregulation of hydrolase activity" EXACT [] is_a: GO:0043085 ! positive regulation of catalytic activity is_a: GO:0051336 ! regulation of hydrolase activity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0016787 ! positively regulates hydrolase activity relationship: RO:0002213 GO:0016787 ! positively regulates hydrolase activity [Term] id: GO:0051346 name: negative regulation of hydrolase activity namespace: biological_process def: "Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds." [GOC:ai] synonym: "down regulation of hydrolase activity" EXACT [] synonym: "down-regulation of hydrolase activity" EXACT [] synonym: "downregulation of hydrolase activity" EXACT [] synonym: "hydrolase inhibitor" EXACT [] is_a: GO:0043086 ! negative regulation of catalytic activity is_a: GO:0051336 ! regulation of hydrolase activity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0016787 ! negatively regulates hydrolase activity relationship: RO:0002212 GO:0016787 ! negatively regulates hydrolase activity [Term] id: GO:0051347 name: positive regulation of transferase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor." [GOC:ai] synonym: "transferase activator" EXACT [] synonym: "up regulation of transferase activity" EXACT [] synonym: "up-regulation of transferase activity" EXACT [] synonym: "upregulation of transferase activity" EXACT [] is_a: GO:0043085 ! positive regulation of catalytic activity is_a: GO:0051338 ! regulation of transferase activity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0016740 ! positively regulates transferase activity relationship: RO:0002213 GO:0016740 ! positively regulates transferase activity [Term] id: GO:0051348 name: negative regulation of transferase activity namespace: biological_process def: "Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor." [GOC:ai] synonym: "down regulation of transferase activity" EXACT [] synonym: "down-regulation of transferase activity" EXACT [] synonym: "downregulation of transferase activity" EXACT [] synonym: "transferase inhibitor" EXACT [] is_a: GO:0043086 ! negative regulation of catalytic activity is_a: GO:0051338 ! regulation of transferase activity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0016740 ! negatively regulates transferase activity relationship: RO:0002212 GO:0016740 ! negatively regulates transferase activity [Term] id: GO:0051402 name: neuron apoptotic process namespace: biological_process def: "Any apoptotic process in a neuron, the basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system." [CL:0000540, GOC:mtg_apoptosis] synonym: "apoptosis of neuronal cells" EXACT [] synonym: "apoptosis of neurons" EXACT [] synonym: "neuron programmed cell death by apoptosis" EXACT [] synonym: "neuronal cell apoptosis" EXACT [] synonym: "neuronal cell programmed cell death by apoptosis" EXACT [] synonym: "programmed cell death of neuronal cells by apoptosis" EXACT [] synonym: "programmed cell death of neurons by apoptosis" EXACT [] synonym: "programmed cell death, neuronal cells" EXACT [] synonym: "programmed cell death, neurons" EXACT [] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000540 ! occurs in neuron relationship: BFO:0000066 CL:0000540 ! occurs in neuron [Term] id: GO:0051410 name: detoxification of nitrogen compound namespace: biological_process def: "Any process that reduces or removes the toxicity of nitrogenous compounds which are dangerous or toxic. This includes the aerobic conversion of toxic compounds to harmless substances." [GOC:ai] synonym: "detoxification of nitrogenous compound" EXACT [] is_a: GO:0098754 ! detoxification intersection_of: GO:0098754 ! detoxification intersection_of: RO:0004009 CHEBI:51143 ! has primary input nitrogen molecular entity relationship: BFO:0000050 GO:1901698 ! part of response to nitrogen compound relationship: RO:0004009 CHEBI:51143 ! has primary input nitrogen molecular entity [Term] id: GO:0051445 name: regulation of meiotic cell cycle namespace: biological_process def: "Any process that modulates the rate or extent of progression through the meiotic cell cycle." [GOC:ai, GOC:dph, GOC:tb] synonym: "meiotic cell cycle modulation" EXACT [] synonym: "meiotic cell cycle regulation" EXACT [] synonym: "modulation of meiotic cell cycle progression" EXACT [] synonym: "regulation of meiotic cell cycle progression" EXACT [] synonym: "regulation of progression through meiotic cell cycle" EXACT [GOC:dph, GOC:tb] is_a: GO:0051726 ! regulation of cell cycle is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0051321 ! regulates (processual) meiotic cell cycle relationship: RO:0002211 GO:0051321 ! regulates (processual) meiotic cell cycle [Term] id: GO:0051446 name: positive regulation of meiotic cell cycle namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle." [GOC:ai, GOC:dph, GOC:tb] synonym: "positive regulation of meiotic cell cycle progression" EXACT [] synonym: "positive regulation of progression through meiotic cell cycle" EXACT [GOC:dph, GOC:tb] synonym: "up regulation of progression through meiotic cell cycle" EXACT [] synonym: "up-regulation of progression through meiotic cell cycle" EXACT [] synonym: "upregulation of progression through meiotic cell cycle" EXACT [] is_a: GO:0045787 ! positive regulation of cell cycle is_a: GO:0051445 ! regulation of meiotic cell cycle is_a: GO:2000243 ! positive regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0051321 ! positively regulates meiotic cell cycle relationship: RO:0002213 GO:0051321 ! positively regulates meiotic cell cycle [Term] id: GO:0051447 name: negative regulation of meiotic cell cycle namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of progression through the meiotic cell cycle." [GOC:ai, GOC:dph, GOC:tb] synonym: "down regulation of progression through meiotic cell cycle" EXACT [] synonym: "down-regulation of progression through meiotic cell cycle" EXACT [] synonym: "downregulation of progression through meiotic cell cycle" EXACT [] synonym: "negative regulation of meiotic cell cycle progression" EXACT [] synonym: "negative regulation of progression through meiotic cell cycle" EXACT [GOC:dph, GOC:tb] is_a: GO:0045786 ! negative regulation of cell cycle is_a: GO:0051445 ! regulation of meiotic cell cycle is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0051321 ! negatively regulates meiotic cell cycle relationship: RO:0002212 GO:0051321 ! negatively regulates meiotic cell cycle [Term] id: GO:0051450 name: myoblast proliferation namespace: biological_process def: "The multiplication or reproduction of myoblasts, resulting in the expansion of a myoblast cell population. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:ai, GOC:mtg_muscle] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000056 ! acts on population of myoblast relationship: RO:0012003 CL:0000056 ! acts on population of myoblast [Term] id: GO:0051451 name: myoblast migration namespace: biological_process def: "The orderly movement of a myoblast from one site to another, often during the development of a multicellular organism. A myoblast is a cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:ai, GOC:mtg_muscle] is_a: GO:0014812 ! muscle cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000056 ! results in movement of myoblast relationship: RO:0002565 CL:0000056 ! results in movement of myoblast [Term] id: GO:0051469 name: vesicle fusion with vacuole namespace: biological_process def: "The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the vacuole." [GOC:ai] is_a: GO:0006906 ! vesicle fusion is_a: GO:0097576 ! vacuole fusion intersection_of: GO:0009987 ! cellular process intersection_of: RO:0012008 GO:0005773 ! results in fusion of vacuole intersection_of: RO:0012008 GO:0031982 ! results in fusion of vesicle relationship: RO:0012008 GO:0031982 ! results in fusion of vesicle [Term] id: GO:0051493 name: regulation of cytoskeleton organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures." [GOC:ai] synonym: "regulation of cytoskeleton organisation" EXACT [GOC:mah] is_a: GO:0033043 ! regulation of organelle organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007010 ! regulates (processual) cytoskeleton organization relationship: RO:0002211 GO:0007010 ! regulates (processual) cytoskeleton organization [Term] id: GO:0051494 name: negative regulation of cytoskeleton organization namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures." [GOC:ai] synonym: "down regulation of cytoskeleton organization" EXACT [] synonym: "down-regulation of cytoskeleton organization" EXACT [] synonym: "downregulation of cytoskeleton organization" EXACT [] synonym: "negative regulation of cytoskeleton organisation" EXACT [GOC:mah] is_a: GO:0010639 ! negative regulation of organelle organization is_a: GO:0051493 ! regulation of cytoskeleton organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007010 ! negatively regulates cytoskeleton organization relationship: RO:0002212 GO:0007010 ! negatively regulates cytoskeleton organization [Term] id: GO:0051495 name: positive regulation of cytoskeleton organization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures." [GOC:ai] synonym: "positive regulation of cytoskeleton organisation" EXACT [GOC:mah] synonym: "up regulation of cytoskeleton organization" EXACT [] synonym: "up-regulation of cytoskeleton organization" EXACT [] synonym: "upregulation of cytoskeleton organization" EXACT [] is_a: GO:0010638 ! positive regulation of organelle organization is_a: GO:0051493 ! regulation of cytoskeleton organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007010 ! positively regulates cytoskeleton organization relationship: RO:0002213 GO:0007010 ! positively regulates cytoskeleton organization [Term] id: GO:0051588 name: regulation of neurotransmitter transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006836 ! regulates (processual) neurotransmitter transport relationship: RO:0002211 GO:0006836 ! regulates (processual) neurotransmitter transport [Term] id: GO:0051589 name: negative regulation of neurotransmitter transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "down regulation of neurotransmitter transport" EXACT [] synonym: "down-regulation of neurotransmitter transport" EXACT [] synonym: "downregulation of neurotransmitter transport" EXACT [] is_a: GO:0051051 ! negative regulation of transport is_a: GO:0051588 ! regulation of neurotransmitter transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006836 ! negatively regulates neurotransmitter transport relationship: RO:0002212 GO:0006836 ! negatively regulates neurotransmitter transport [Term] id: GO:0051590 name: positive regulation of neurotransmitter transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "up regulation of neurotransmitter transport" EXACT [] synonym: "up-regulation of neurotransmitter transport" EXACT [] synonym: "upregulation of neurotransmitter transport" EXACT [] is_a: GO:0051050 ! positive regulation of transport is_a: GO:0051588 ! regulation of neurotransmitter transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006836 ! positively regulates neurotransmitter transport relationship: RO:0002213 GO:0006836 ! positively regulates neurotransmitter transport [Term] id: GO:0051602 name: response to electrical stimulus namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus." [GOC:ai] is_a: GO:0009628 ! response to abiotic stimulus [Term] id: GO:0051606 name: detection of stimulus namespace: biological_process def: "The series of events in which a stimulus is received by a cell or organism and converted into a molecular signal." [GOC:add, GOC:ai, GOC:dph, GOC:mah] synonym: "stimulus detection" EXACT [] is_a: GO:0050896 ! response to stimulus [Term] id: GO:0051620 name: norepinephrine uptake namespace: biological_process def: "The directed movement of norepinephrine into a cell, typically presynaptic neurons or glial cells. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine." [GOC:ai] synonym: "levarterenol reuptake" EXACT [] synonym: "levarterenol uptake" EXACT [] synonym: "noradrenaline reuptake" EXACT [] synonym: "noradrenaline uptake" EXACT [] synonym: "norepinephrine import" EXACT [GOC:dph, GOC:tb] synonym: "norepinephrine reuptake" EXACT [] is_a: GO:0015874 ! norepinephrine transport is_a: GO:0090493 ! catecholamine uptake intersection_of: GO:0006810 ! transport intersection_of: RO:0002338 GO:0005576 ! has target start location extracellular region intersection_of: RO:0002339 GO:0005622 ! has target end location intracellular anatomical structure intersection_of: RO:0004009 CHEBI:72587 ! has primary input (R)-noradrenaline(1+) [Term] id: GO:0051621 name: regulation of norepinephrine uptake namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter norepinephrine into a cell." [GOC:ai] synonym: "regulation of levarterenol uptake" EXACT [] synonym: "regulation of noradrenaline uptake" EXACT [] synonym: "regulation of norepinephrine import" EXACT [GOC:dph, GOC:tb] is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0051620 ! regulates (processual) norepinephrine uptake relationship: RO:0002211 GO:0051620 ! regulates (processual) norepinephrine uptake [Term] id: GO:0051622 name: negative regulation of norepinephrine uptake namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of norepinephrine into a cell." [GOC:ai] synonym: "down regulation of norepinephrine uptake" EXACT [] synonym: "down-regulation of norepinephrine uptake" EXACT [] synonym: "downregulation of norepinephrine uptake" EXACT [] synonym: "negative regulation of levarterenol uptake" EXACT [] synonym: "negative regulation of noradrenaline uptake" EXACT [] synonym: "negative regulation of norepinephrine import" EXACT [GOC:dph, GOC:tb] is_a: GO:0051051 ! negative regulation of transport is_a: GO:0051621 ! regulation of norepinephrine uptake intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0051620 ! negatively regulates norepinephrine uptake relationship: RO:0002212 GO:0051620 ! negatively regulates norepinephrine uptake [Term] id: GO:0051623 name: positive regulation of norepinephrine uptake namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the directed movement of norepinephrine into a cell." [GOC:ai] synonym: "positive regulation of levarterenol uptake" EXACT [] synonym: "positive regulation of noradrenaline uptake" EXACT [] synonym: "positive regulation of norepinephrine import" EXACT [GOC:dph, GOC:tb] synonym: "up regulation of norepinephrine uptake" EXACT [] synonym: "up-regulation of norepinephrine uptake" EXACT [] synonym: "upregulation of norepinephrine uptake" EXACT [] is_a: GO:0051050 ! positive regulation of transport is_a: GO:0051621 ! regulation of norepinephrine uptake intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0051620 ! positively regulates norepinephrine uptake relationship: RO:0002213 GO:0051620 ! positively regulates norepinephrine uptake [Term] id: GO:0051630 name: acetylcholine uptake namespace: biological_process def: "The directed movement of acetylcholine into a cell, typically presynaptic neurons or glial cells. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." [GOC:ai] synonym: "acetylcholine import" EXACT [GOC:dph, GOC:tb] is_a: GO:0015870 ! acetylcholine transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002338 GO:0005576 ! has target start location extracellular region intersection_of: RO:0002339 GO:0005622 ! has target end location intracellular anatomical structure intersection_of: RO:0004009 CHEBI:15355 ! has primary input acetylcholine relationship: RO:0002338 GO:0005576 ! has target start location extracellular region relationship: RO:0002339 GO:0005622 ! has target end location intracellular anatomical structure [Term] id: GO:0051631 name: regulation of acetylcholine uptake namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter acetylcholine into a cell." [GOC:ai] synonym: "regulation of acetylcholine import" EXACT [GOC:dph, GOC:tb] is_a: GO:0051952 ! regulation of amine transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0051630 ! regulates (processual) acetylcholine uptake relationship: RO:0002211 GO:0051630 ! regulates (processual) acetylcholine uptake [Term] id: GO:0051632 name: negative regulation of acetylcholine uptake namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of acetylcholine into a cell." [GOC:ai] synonym: "down regulation of acetylcholine uptake" EXACT [] synonym: "down-regulation of acetylcholine uptake" EXACT [] synonym: "downregulation of acetylcholine uptake" EXACT [] synonym: "negative regulation of acetylcholine import" EXACT [GOC:dph, GOC:tb] is_a: GO:0051631 ! regulation of acetylcholine uptake is_a: GO:0051953 ! negative regulation of amine transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0051630 ! negatively regulates acetylcholine uptake relationship: RO:0002212 GO:0051630 ! negatively regulates acetylcholine uptake [Term] id: GO:0051633 name: positive regulation of acetylcholine uptake namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the directed movement of acetylcholine into a cell." [GOC:ai] synonym: "positive regulation of acetylcholine import" EXACT [GOC:dph, GOC:tb] synonym: "up regulation of acetylcholine uptake" EXACT [] synonym: "up-regulation of acetylcholine uptake" EXACT [] synonym: "upregulation of acetylcholine uptake" EXACT [] is_a: GO:0051631 ! regulation of acetylcholine uptake is_a: GO:0051954 ! positive regulation of amine transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0051630 ! positively regulates acetylcholine uptake relationship: RO:0002213 GO:0051630 ! positively regulates acetylcholine uptake [Term] id: GO:0051640 name: organelle localization namespace: biological_process def: "Any process in which an organelle is transported to, and/or maintained in, a specific location." [GOC:ai] synonym: "establishment and maintenance of organelle localization" EXACT [] synonym: "organelle localisation" EXACT [GOC:mah] is_a: GO:0051179 ! localization intersection_of: GO:0051179 ! localization intersection_of: RO:0004009 GO:0043226 ! has primary input organelle relationship: RO:0002160 NCBITaxon:2759 ! only in taxon Eukaryota relationship: RO:0002162 NCBITaxon:2759 {all_only="true"} ! in taxon Eukaryota relationship: RO:0004009 GO:0043226 ! has primary input organelle [Term] id: GO:0051641 name: cellular localization namespace: biological_process def: "A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane." [GOC:tb, GOC:vw] synonym: "cellular localisation" EXACT [GOC:mah] synonym: "establishment and maintenance of cellular localization" EXACT [] synonym: "establishment and maintenance of localization in cell or cell membrane" EXACT [] synonym: "single organism cellular localization" EXACT [GOC:TermGenie] is_a: GO:0009987 ! cellular process is_a: GO:0051179 ! localization creation_date: 2013-12-18T14:04:32Z [Term] id: GO:0051645 name: Golgi localization namespace: biological_process def: "Any process in which the Golgi is transported to, and/or maintained in, a specific location within the cell." [GOC:ai] synonym: "establishment and maintenance of Golgi localization" EXACT [] synonym: "Golgi apparatus localization" EXACT [] synonym: "Golgi body localization" EXACT [] synonym: "Golgi localisation" EXACT [GOC:mah] is_a: GO:0051640 ! organelle localization intersection_of: GO:0051179 ! localization intersection_of: RO:0004009 GO:0005794 ! has primary input Golgi apparatus relationship: RO:0004009 GO:0005794 ! has primary input Golgi apparatus [Term] id: GO:0051647 name: nucleus localization namespace: biological_process def: "Any process in which the nucleus is transported to, and/or maintained in, a specific location within the cell." [GOC:ai] synonym: "cell nucleus localization" EXACT [] synonym: "establishment and maintenance of nucleus localization" EXACT [] synonym: "localization of nucleus" EXACT [] synonym: "nucleus localisation" EXACT [GOC:mah] is_a: GO:0051640 ! organelle localization intersection_of: GO:0051179 ! localization intersection_of: RO:0004009 GO:0005634 ! has primary input nucleus relationship: RO:0004009 GO:0005634 ! has primary input nucleus [Term] id: GO:0051648 name: vesicle localization namespace: biological_process def: "Any process in which a vesicle or vesicles are transported to, and/or maintained in, a specific location." [GOC:ai] synonym: "cytoplasmic vesicle localization" EXACT [] synonym: "establishment and maintenance of vesicle localization" EXACT [] synonym: "vesicle localisation" EXACT [GOC:mah] is_a: GO:0051640 ! organelle localization intersection_of: GO:0051179 ! localization intersection_of: RO:0004009 GO:0031982 ! has primary input vesicle relationship: RO:0004009 GO:0031982 ! has primary input vesicle [Term] id: GO:0051649 name: establishment of localization in cell namespace: biological_process def: "Any process, occuring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation." [GOC:ai, GOC:dos, GOC:dph, GOC:tb] synonym: "establishment of localisation in cell" EXACT [GOC:mah] is_a: GO:0051234 ! establishment of localization intersection_of: GO:0051234 ! establishment of localization intersection_of: BFO:0000066 CL:0000000 ! occurs in cell relationship: BFO:0000050 GO:0051641 ! part of cellular localization relationship: BFO:0000066 CL:0000000 ! occurs in cell relationship: RO:0002160 NCBITaxon:131567 ! only in taxon cellular organisms relationship: RO:0002162 NCBITaxon:131567 {all_only="true"} ! in taxon cellular organisms [Term] id: GO:0051650 name: establishment of vesicle localization namespace: biological_process def: "The directed movement of a vesicle to a specific location." [GOC:ai] synonym: "establishment of vesicle localisation" EXACT [GOC:mah] is_a: GO:0051648 ! vesicle localization is_a: GO:0051649 ! establishment of localization in cell is_a: GO:0051656 ! establishment of organelle localization intersection_of: GO:0051234 ! establishment of localization intersection_of: RO:0004009 GO:0031982 ! has primary input vesicle [Term] id: GO:0051656 name: establishment of organelle localization namespace: biological_process def: "The directed movement of an organelle to a specific location." [GOC:ai] synonym: "establishment of organelle localisation" EXACT [GOC:mah] is_a: GO:0051234 ! establishment of localization is_a: GO:0051640 ! organelle localization intersection_of: GO:0051234 ! establishment of localization intersection_of: RO:0004009 GO:0043226 ! has primary input organelle [Term] id: GO:0051668 name: localization within membrane namespace: biological_process def: "Any process in which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a membrane." [GOC:ai] synonym: "establishment and maintenance of localization in membrane" EXACT [] synonym: "establishment and maintenance of position in membrane" EXACT [] synonym: "localisation within membrane" EXACT [GOC:mah] synonym: "localization to membrane" EXACT [] is_a: GO:0051641 ! cellular localization intersection_of: GO:0051179 ! localization intersection_of: RO:0002339 GO:0016020 ! has target end location membrane relationship: RO:0002339 GO:0016020 ! has target end location membrane [Term] id: GO:0051674 name: localization of cell namespace: biological_process def: "Any process in which a cell is transported to, and/or maintained in, a specific location." [GOC:ai] synonym: "cell localization" EXACT [] synonym: "establishment and maintenance of cell localization" EXACT [] synonym: "establishment and maintenance of localization of cell" EXACT [] synonym: "localisation of cell" EXACT [GOC:mah] is_a: GO:0009987 ! cellular process is_a: GO:0051179 ! localization intersection_of: GO:0051179 ! localization intersection_of: RO:0004009 CL:0000000 ! has primary input cell relationship: RO:0004009 CL:0000000 ! has primary input cell [Term] id: GO:0051683 name: establishment of Golgi localization namespace: biological_process def: "The directed movement of the Golgi to a specific location." [GOC:ai] synonym: "establishment of Golgi apparatus localization" EXACT [] synonym: "establishment of Golgi body localization" EXACT [] synonym: "establishment of Golgi localisation" EXACT [GOC:mah] is_a: GO:0051645 ! Golgi localization is_a: GO:0051649 ! establishment of localization in cell is_a: GO:0051656 ! establishment of organelle localization intersection_of: GO:0051234 ! establishment of localization intersection_of: RO:0004009 GO:0005794 ! has primary input Golgi apparatus [Term] id: GO:0051707 name: response to other organism namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism." [GOC:ai] is_a: GO:0043207 ! response to external biotic stimulus is_a: GO:0044419 ! biological process involved in interspecies interaction between organisms intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 NCBITaxon_Union:0000030 ! has primary input relationship: RO:0004009 NCBITaxon_Union:0000030 ! has primary input [Term] id: GO:0051716 name: cellular response to stimulus namespace: biological_process def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell." [GOC:bf, GOC:jl] is_a: GO:0009987 ! cellular process is_a: GO:0050896 ! response to stimulus [Term] id: GO:0051726 name: regulation of cell cycle namespace: biological_process def: "Any process that modulates the rate or extent of progression through the cell cycle." [GOC:ai, GOC:dph, GOC:tb] synonym: "cell cycle modulation" EXACT [] synonym: "cell cycle regulation" EXACT [] synonym: "control of cell cycle progression" EXACT [] synonym: "modulation of cell cycle progression" EXACT [] synonym: "regulation of cell cycle progression" EXACT [] synonym: "regulation of progression through cell cycle" EXACT [] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007049 ! regulates (processual) cell cycle relationship: RO:0002211 GO:0007049 ! regulates (processual) cell cycle [Term] id: GO:0051781 name: positive regulation of cell division namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell division." [GOC:ai] synonym: "up regulation of cell division" EXACT [] synonym: "up-regulation of cell division" EXACT [] synonym: "upregulation of cell division" EXACT [] is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:0051302 ! regulation of cell division intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0051301 ! positively regulates cell division relationship: RO:0002213 GO:0051301 ! positively regulates cell division [Term] id: GO:0051782 name: negative regulation of cell division namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell division." [GOC:ai] synonym: "down regulation of cell division" EXACT [] synonym: "down-regulation of cell division" EXACT [] synonym: "downregulation of cell division" EXACT [] is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:0051302 ! regulation of cell division intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0051301 ! negatively regulates cell division relationship: RO:0002212 GO:0051301 ! negatively regulates cell division [Term] id: GO:0051783 name: regulation of nuclear division namespace: biological_process def: "Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information." [GOC:ai] is_a: GO:0033043 ! regulation of organelle organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0000280 ! regulates (processual) nuclear division relationship: RO:0002211 GO:0000280 ! regulates (processual) nuclear division [Term] id: GO:0051784 name: negative regulation of nuclear division namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information." [GOC:ai] synonym: "down regulation of nuclear division" EXACT [] synonym: "down-regulation of nuclear division" EXACT [] synonym: "downregulation of nuclear division" EXACT [] is_a: GO:0010639 ! negative regulation of organelle organization is_a: GO:0051783 ! regulation of nuclear division intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0000280 ! negatively regulates nuclear division relationship: RO:0002212 GO:0000280 ! negatively regulates nuclear division [Term] id: GO:0051785 name: positive regulation of nuclear division namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information." [GOC:ai] synonym: "up regulation of nuclear division" EXACT [] synonym: "up-regulation of nuclear division" EXACT [] synonym: "upregulation of nuclear division" EXACT [] is_a: GO:0010638 ! positive regulation of organelle organization is_a: GO:0051783 ! regulation of nuclear division intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0000280 ! positively regulates nuclear division relationship: RO:0002213 GO:0000280 ! positively regulates nuclear division [Term] id: GO:0051875 name: pigment granule localization namespace: biological_process def: "Any process in which a pigment granule is transported to, and/or maintained in, a specific location within the cell." [GOC:ai] synonym: "pigment granule localisation" EXACT [GOC:mah] is_a: GO:0051648 ! vesicle localization intersection_of: GO:0051179 ! localization intersection_of: RO:0004009 GO:0048770 ! has primary input pigment granule relationship: BFO:0000050 GO:0033059 ! part of cellular pigmentation relationship: RO:0004009 GO:0048770 ! has primary input pigment granule [Term] id: GO:0051890 name: regulation of cardioblast differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:ai] is_a: GO:1905207 ! regulation of cardiocyte differentiation is_a: GO:2000736 ! regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0010002 ! regulates (processual) cardioblast differentiation relationship: RO:0002211 GO:0010002 ! regulates (processual) cardioblast differentiation [Term] id: GO:0051891 name: positive regulation of cardioblast differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:ai] synonym: "up regulation of cardioblast differentiation" EXACT [] synonym: "up-regulation of cardioblast differentiation" EXACT [] synonym: "upregulation of cardioblast differentiation" EXACT [] is_a: GO:0051890 ! regulation of cardioblast differentiation is_a: GO:1905209 ! positive regulation of cardiocyte differentiation is_a: GO:2000738 ! positive regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0010002 ! positively regulates cardioblast differentiation relationship: RO:0002213 GO:0010002 ! positively regulates cardioblast differentiation [Term] id: GO:0051892 name: negative regulation of cardioblast differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:ai] synonym: "down regulation of cardioblast differentiation" EXACT [] synonym: "down-regulation of cardioblast differentiation" EXACT [] synonym: "downregulation of cardioblast differentiation" EXACT [] is_a: GO:0051890 ! regulation of cardioblast differentiation is_a: GO:1905208 ! negative regulation of cardiocyte differentiation is_a: GO:2000737 ! negative regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0010002 ! negatively regulates cardioblast differentiation relationship: RO:0002212 GO:0010002 ! negatively regulates cardioblast differentiation [Term] id: GO:0051904 name: pigment granule transport namespace: biological_process def: "The directed movement of pigment granules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "pigment granule translocation" EXACT [] is_a: GO:0006810 ! transport is_a: GO:0051875 ! pigment granule localization is_a: GO:0051905 ! establishment of pigment granule localization intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 GO:0048770 ! has primary input pigment granule [Term] id: GO:0051905 name: establishment of pigment granule localization namespace: biological_process def: "The directed movement of a pigment granule to a specific location." [GOC:ai] synonym: "establishment of pigment granule localisation" EXACT [GOC:mah] is_a: GO:0051650 ! establishment of vesicle localization relationship: BFO:0000050 GO:0051875 ! part of pigment granule localization [Term] id: GO:0051930 name: regulation of sensory perception of pain namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal." [GOC:ai] is_a: GO:0051931 ! regulation of sensory perception intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0019233 ! regulates (processual) sensory perception of pain relationship: RO:0002211 GO:0019233 ! regulates (processual) sensory perception of pain [Term] id: GO:0051931 name: regulation of sensory perception namespace: biological_process def: "Any process that modulates the frequency, rate or extent of sensory perception, the series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal." [GOC:ai] is_a: GO:0031644 ! regulation of nervous system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007600 ! regulates (processual) sensory perception relationship: RO:0002211 GO:0007600 ! regulates (processual) sensory perception [Term] id: GO:0051937 name: catecholamine transport namespace: biological_process def: "The directed movement of catecholamines, a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." [GOC:ai, ISBN:0198506732] is_a: GO:0015844 ! monoamine transport is_a: GO:0015850 ! organic hydroxy compound transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:33567 ! has primary input catecholamine relationship: RO:0004009 CHEBI:33567 ! has primary input catecholamine [Term] id: GO:0051952 name: regulation of amine transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0015837 ! regulates (processual) amine transport relationship: RO:0002211 GO:0015837 ! regulates (processual) amine transport [Term] id: GO:0051953 name: negative regulation of amine transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "down regulation of amine transport" EXACT [] synonym: "down-regulation of amine transport" EXACT [] synonym: "downregulation of amine transport" EXACT [] is_a: GO:0051051 ! negative regulation of transport is_a: GO:0051952 ! regulation of amine transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0015837 ! negatively regulates amine transport relationship: RO:0002212 GO:0015837 ! negatively regulates amine transport [Term] id: GO:0051954 name: positive regulation of amine transport namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "up regulation of amine transport" EXACT [] synonym: "up-regulation of amine transport" EXACT [] synonym: "upregulation of amine transport" EXACT [] is_a: GO:0051050 ! positive regulation of transport is_a: GO:0051952 ! regulation of amine transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0015837 ! positively regulates amine transport relationship: RO:0002213 GO:0015837 ! positively regulates amine transport [Term] id: GO:0051955 name: regulation of amino acid transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] is_a: GO:0032890 ! regulation of organic acid transport is_a: GO:0051952 ! regulation of amine transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006865 ! regulates (processual) amino acid transport relationship: RO:0002211 GO:0006865 ! regulates (processual) amino acid transport [Term] id: GO:0051956 name: negative regulation of amino acid transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "down regulation of amino acid transport" EXACT [] synonym: "down-regulation of amino acid transport" EXACT [] synonym: "downregulation of amino acid transport" EXACT [] synonym: "negative regulation of amino acid transmembrane transport" EXACT [GOC:mah] is_a: GO:0032891 ! negative regulation of organic acid transport is_a: GO:0051953 ! negative regulation of amine transport is_a: GO:0051955 ! regulation of amino acid transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006865 ! negatively regulates amino acid transport relationship: RO:0002212 GO:0006865 ! negatively regulates amino acid transport [Term] id: GO:0051957 name: positive regulation of amino acid transport namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "positive regulation of amino acid transmembrane transport" EXACT [GOC:mah] synonym: "up regulation of amino acid transport" EXACT [] synonym: "up-regulation of amino acid transport" EXACT [] synonym: "upregulation of amino acid transport" EXACT [] is_a: GO:0032892 ! positive regulation of organic acid transport is_a: GO:0051954 ! positive regulation of amine transport is_a: GO:0051955 ! regulation of amino acid transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006865 ! positively regulates amino acid transport relationship: RO:0002213 GO:0006865 ! positively regulates amino acid transport [Term] id: GO:0051960 name: regulation of nervous system development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue." [GOC:ai] is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007399 ! regulates (processual) nervous system development relationship: RO:0002211 GO:0007399 ! regulates (processual) nervous system development [Term] id: GO:0051961 name: negative regulation of nervous system development namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue." [GOC:ai] synonym: "down regulation of nervous system development" EXACT [] synonym: "down-regulation of nervous system development" EXACT [] synonym: "downregulation of nervous system development" EXACT [] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:0051960 ! regulation of nervous system development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007399 ! negatively regulates nervous system development relationship: RO:0002212 GO:0007399 ! negatively regulates nervous system development [Term] id: GO:0051962 name: positive regulation of nervous system development namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue." [GOC:ai] synonym: "up regulation of nervous system development" EXACT [] synonym: "up-regulation of nervous system development" EXACT [] synonym: "upregulation of nervous system development" EXACT [] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:0051960 ! regulation of nervous system development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007399 ! positively regulates nervous system development relationship: RO:0002213 GO:0007399 ! positively regulates nervous system development [Term] id: GO:0051963 name: regulation of synapse assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse." [GOC:ai, GOC:pr] synonym: "regulation of synapse biogenesis" EXACT [] synonym: "regulation of synaptogenesis" EXACT [] is_a: GO:0050807 ! regulation of synapse organization is_a: GO:1901888 ! regulation of cell junction assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007416 ! regulates (processual) synapse assembly relationship: RO:0002211 GO:0007416 ! regulates (processual) synapse assembly [Term] id: GO:0051964 name: negative regulation of synapse assembly namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse." [GOC:ai, GOC:pr] synonym: "down regulation of synapse assembly" EXACT [] synonym: "down-regulation of synapse assembly" EXACT [] synonym: "downregulation of synapse assembly" EXACT [] synonym: "negative regulation of synapse biogenesis" EXACT [] synonym: "negative regulation of synaptogenesis" EXACT [] is_a: GO:0051961 ! negative regulation of nervous system development is_a: GO:0051963 ! regulation of synapse assembly is_a: GO:1901889 ! negative regulation of cell junction assembly is_a: GO:1905809 ! negative regulation of synapse organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007416 ! negatively regulates synapse assembly relationship: RO:0002212 GO:0007416 ! negatively regulates synapse assembly [Term] id: GO:0051965 name: positive regulation of synapse assembly namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse." [GOC:ai, GOC:pr] synonym: "positive regulation of synapse biogenesis" EXACT [] synonym: "positive regulation of synaptogenesis" EXACT [] synonym: "up regulation of synapse assembly" EXACT [] synonym: "up-regulation of synapse assembly" EXACT [] synonym: "upregulation of synapse assembly" EXACT [] is_a: GO:0051962 ! positive regulation of nervous system development is_a: GO:0051963 ! regulation of synapse assembly is_a: GO:1901890 ! positive regulation of cell junction assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007416 ! positively regulates synapse assembly relationship: RO:0002213 GO:0007416 ! positively regulates synapse assembly [Term] id: GO:0051969 name: regulation of transmission of nerve impulse namespace: biological_process def: "Any process that modulates the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation." [GOC:ai] synonym: "regulation of conduction of nerve impulse" EXACT [GOC:dph] is_a: GO:0010646 ! regulation of cell communication is_a: GO:0031644 ! regulation of nervous system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0019226 ! regulates (processual) transmission of nerve impulse relationship: RO:0002211 GO:0019226 ! regulates (processual) transmission of nerve impulse [Term] id: GO:0051970 name: negative regulation of transmission of nerve impulse namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation." [GOC:ai] synonym: "down regulation of transmission of nerve impulse" EXACT [] synonym: "down-regulation of transmission of nerve impulse" EXACT [] synonym: "downregulation of transmission of nerve impulse" EXACT [] synonym: "negative regulation of conduction of nerve impulse" EXACT [GOC:dph] is_a: GO:0010648 ! negative regulation of cell communication is_a: GO:0031645 ! negative regulation of nervous system process is_a: GO:0051969 ! regulation of transmission of nerve impulse intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0019226 ! negatively regulates transmission of nerve impulse relationship: RO:0002212 GO:0019226 ! negatively regulates transmission of nerve impulse [Term] id: GO:0051971 name: positive regulation of transmission of nerve impulse namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation." [GOC:ai] synonym: "positive regulation of conduction of nerve impulse" EXACT [GOC:dph] synonym: "up regulation of transmission of nerve impulse" EXACT [] synonym: "up-regulation of transmission of nerve impulse" EXACT [] synonym: "upregulation of transmission of nerve impulse" EXACT [] is_a: GO:0010647 ! positive regulation of cell communication is_a: GO:0031646 ! positive regulation of nervous system process is_a: GO:0051969 ! regulation of transmission of nerve impulse intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0019226 ! positively regulates transmission of nerve impulse relationship: RO:0002213 GO:0019226 ! positively regulates transmission of nerve impulse [Term] id: GO:0051983 name: regulation of chromosome segregation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets." [GOC:ai] is_a: GO:0010564 ! regulation of cell cycle process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007059 ! regulates (processual) chromosome segregation relationship: RO:0002211 GO:0007059 ! regulates (processual) chromosome segregation [Term] id: GO:0051984 name: positive regulation of chromosome segregation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets." [GOC:ai] synonym: "up regulation of chromosome segregation" EXACT [] synonym: "up-regulation of chromosome segregation" EXACT [] synonym: "upregulation of chromosome segregation" EXACT [] is_a: GO:0051983 ! regulation of chromosome segregation is_a: GO:0090068 ! positive regulation of cell cycle process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007059 ! positively regulates chromosome segregation relationship: RO:0002213 GO:0007059 ! positively regulates chromosome segregation [Term] id: GO:0051985 name: negative regulation of chromosome segregation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets." [GOC:ai] synonym: "down regulation of chromosome segregation" EXACT [] synonym: "down-regulation of chromosome segregation" EXACT [] synonym: "downregulation of chromosome segregation" EXACT [] is_a: GO:0010948 ! negative regulation of cell cycle process is_a: GO:0051983 ! regulation of chromosome segregation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007059 ! negatively regulates chromosome segregation relationship: RO:0002212 GO:0007059 ! negatively regulates chromosome segregation [Term] id: GO:0055001 name: muscle cell development namespace: biological_process def: "The process whose specific outcome is the progression of a muscle cell over time, from its formation to the mature structure. Muscle cell development does not include the steps involved in committing an unspecified cell to the muscle cell fate." [CL:0000187, GOC:devbiol] synonym: "muscle fiber development" EXACT [] synonym: "muscle fibre development" EXACT [] synonym: "myofiber development" EXACT [] synonym: "myofibre development" EXACT [] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000187 ! results in development of muscle cell relationship: BFO:0000050 GO:0042692 ! part of muscle cell differentiation relationship: RO:0002296 CL:0000187 ! results in development of muscle cell [Term] id: GO:0055002 name: striated muscle cell development namespace: biological_process def: "The process whose specific outcome is the progression of a striated muscle cell over time, from its formation to the mature structure. Striated muscle cells contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle." [CL:0000737, GOC:devbiol] is_a: GO:0055001 ! muscle cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000737 ! results in development of striated muscle cell relationship: BFO:0000050 GO:0051146 ! part of striated muscle cell differentiation relationship: RO:0002296 CL:0000737 ! results in development of striated muscle cell [Term] id: GO:0055003 name: cardiac myofibril assembly namespace: biological_process def: "The process whose specific outcome is the progression of the cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells." [GOC:devbiol] synonym: "cardiac myofibril development" EXACT [] synonym: "cardiac myofibril morphogenesis" EXACT [] is_a: GO:0030239 ! myofibril assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0097512 ! results in assembly of cardiac myofibril relationship: BFO:0000050 GO:0055013 ! part of cardiac muscle cell development relationship: RO:0002588 GO:0097512 ! results in assembly of cardiac myofibril [Term] id: GO:0055006 name: cardiac cell development namespace: biological_process def: "The process whose specific outcome is the progression of a cardiac cell over time, from its formation to the mature state. A cardiac cell is a cell that will form part of the cardiac organ of an individual." [GOC:devbiol] synonym: "cardiocyte development" EXACT [GOC:dph] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0002494 ! results in development of cardiocyte relationship: BFO:0000050 GO:0035051 ! part of cardiocyte differentiation relationship: RO:0002296 CL:0002494 ! results in development of cardiocyte [Term] id: GO:0055007 name: cardiac muscle cell differentiation namespace: biological_process def: "The process in which a cardiac muscle precursor cell acquires specialized features of a cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction." [GOC:devbiol, GOC:mtg_heart] synonym: "cardiomyocyte differentiation" EXACT [] is_a: GO:0035051 ! cardiocyte differentiation is_a: GO:0051146 ! striated muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000746 ! results in acquisition of features of cardiac muscle cell relationship: BFO:0000050 GO:0048738 ! part of cardiac muscle tissue development relationship: RO:0002315 CL:0000746 ! results in acquisition of features of cardiac muscle cell [Term] id: GO:0055008 name: cardiac muscle tissue morphogenesis namespace: biological_process def: "The process in which the anatomical structures of cardiac muscle tissue are generated and organized." [GOC:devbiol] synonym: "heart muscle morphogenesis" EXACT [] is_a: GO:0060415 ! muscle tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001133 ! results in morphogenesis of cardiac muscle tissue relationship: BFO:0000050 GO:0003007 ! part of heart morphogenesis relationship: BFO:0000050 GO:0048738 ! part of cardiac muscle tissue development relationship: RO:0002298 UBERON:0001133 ! results in morphogenesis of cardiac muscle tissue [Term] id: GO:0055009 name: atrial cardiac muscle tissue morphogenesis namespace: biological_process def: "The process in which the anatomical structure of cardiac atrium muscle is generated and organized." [GOC:devbiol] synonym: "atrial heart muscle morphogenesis" EXACT [] synonym: "atrial myocardium morphogenesis" EXACT [GOC:mtg_heart] synonym: "cardiac atrium muscle morphogenesis" EXACT [] is_a: GO:0055008 ! cardiac muscle tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0004490 ! results in morphogenesis of cardiac muscle tissue of atrium relationship: BFO:0000050 GO:0003209 ! part of cardiac atrium morphogenesis relationship: BFO:0000050 GO:0003228 ! part of atrial cardiac muscle tissue development relationship: RO:0002298 UBERON:0004490 ! results in morphogenesis of cardiac muscle tissue of atrium [Term] id: GO:0055010 name: ventricular cardiac muscle tissue morphogenesis namespace: biological_process def: "The process in which the anatomical structures of cardiac ventricle muscle is generated and organized." [GOC:devbiol] synonym: "cardiac ventricle muscle morphogenesis" EXACT [] synonym: "ventricular heart muscle morphogenesis" EXACT [] is_a: GO:0055008 ! cardiac muscle tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0018649 ! results in morphogenesis of cardiac muscle tissue of ventricle relationship: BFO:0000050 GO:0003208 ! part of cardiac ventricle morphogenesis relationship: BFO:0000050 GO:0003229 ! part of ventricular cardiac muscle tissue development relationship: RO:0002298 UBERON:0018649 ! results in morphogenesis of cardiac muscle tissue of ventricle [Term] id: GO:0055013 name: cardiac muscle cell development namespace: biological_process def: "The process whose specific outcome is the progression of a cardiac muscle cell over time, from its formation to the mature state." [GOC:devbiol, GOC:mtg_heart] synonym: "cardiac muscle fiber development" EXACT [] synonym: "cardiac muscle fibre development" EXACT [] synonym: "cardiomyocyte cell development" EXACT [GOC:mtg_muscle] synonym: "heart muscle cell development" EXACT [] is_a: GO:0055002 ! striated muscle cell development is_a: GO:0055006 ! cardiac cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000746 ! results in development of cardiac muscle cell relationship: BFO:0000050 GO:0055007 ! part of cardiac muscle cell differentiation relationship: RO:0002296 CL:0000746 ! results in development of cardiac muscle cell [Term] id: GO:0055017 name: cardiac muscle tissue growth namespace: biological_process def: "The increase in size or mass of a cardiac muscle, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another." [GOC:devbiol] synonym: "heart muscle growth" EXACT [] is_a: GO:0048589 ! developmental growth intersection_of: GO:0048589 ! developmental growth intersection_of: RO:0002343 UBERON:0001133 ! results in growth of cardiac muscle tissue relationship: BFO:0000050 GO:0048738 ! part of cardiac muscle tissue development relationship: BFO:0000050 GO:0060419 ! part of heart growth relationship: RO:0002343 UBERON:0001133 ! results in growth of cardiac muscle tissue [Term] id: GO:0055018 name: regulation of cardiac muscle fiber development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac muscle fiber development." [GOC:vk] synonym: "regulation of cardiac muscle fibre development" EXACT [] synonym: "regulation of heart muscle fiber development" EXACT [] is_a: GO:0060284 ! regulation of cell development is_a: GO:2000725 ! regulation of cardiac muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0055013 ! regulates (processual) cardiac muscle cell development relationship: RO:0002211 GO:0055013 ! regulates (processual) cardiac muscle cell development [Term] id: GO:0055019 name: negative regulation of cardiac muscle fiber development namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle fiber development." [GOC:vk] synonym: "down regulation of cardiac muscle fiber development" EXACT [] synonym: "down-regulation of cardiac muscle fiber development" EXACT [] synonym: "downregulation of cardiac muscle fiber development" EXACT [] synonym: "negative regulation of cardiac muscle fibre development" EXACT [] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0051154 ! negative regulation of striated muscle cell differentiation is_a: GO:0055018 ! regulation of cardiac muscle fiber development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0055013 ! negatively regulates cardiac muscle cell development relationship: RO:0002212 GO:0055013 ! negatively regulates cardiac muscle cell development [Term] id: GO:0055020 name: positive regulation of cardiac muscle fiber development namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle fiber development." [GOC:vk] synonym: "positive regulation of cardiac muscle fibre development" EXACT [] synonym: "positive regulation of heart muscle fiber development" EXACT [] synonym: "up regulation of cardiac muscle fiber development" EXACT [] synonym: "up-regulation of cardiac muscle fiber development" EXACT [] synonym: "upregulation of cardiac muscle fiber development" EXACT [] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0055018 ! regulation of cardiac muscle fiber development is_a: GO:2000727 ! positive regulation of cardiac muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0055013 ! positively regulates cardiac muscle cell development relationship: RO:0002213 GO:0055013 ! positively regulates cardiac muscle cell development [Term] id: GO:0055021 name: regulation of cardiac muscle tissue growth namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac muscle growth." [GOC:vk] is_a: GO:0060420 ! regulation of heart growth intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0055017 ! regulates (processual) cardiac muscle tissue growth relationship: RO:0002211 GO:0055017 ! regulates (processual) cardiac muscle tissue growth [Term] id: GO:0055022 name: negative regulation of cardiac muscle tissue growth namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle growth." [GOC:vk] synonym: "down regulation of cardiac muscle growth" EXACT [] synonym: "down-regulation of cardiac muscle growth" EXACT [] synonym: "downregulation of cardiac muscle growth" EXACT [] is_a: GO:0055021 ! regulation of cardiac muscle tissue growth is_a: GO:0061117 ! negative regulation of heart growth intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0055017 ! negatively regulates cardiac muscle tissue growth relationship: RO:0002212 GO:0055017 ! negatively regulates cardiac muscle tissue growth [Term] id: GO:0055023 name: positive regulation of cardiac muscle tissue growth namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle growth." [GOC:vk] synonym: "positive regulation of heart muscle growth" EXACT [] synonym: "up regulation of cardiac muscle growth" EXACT [] synonym: "up-regulation of cardiac muscle growth" EXACT [] synonym: "upregulation of cardiac muscle growth" EXACT [] is_a: GO:0055021 ! regulation of cardiac muscle tissue growth is_a: GO:0060421 ! positive regulation of heart growth intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0055017 ! positively regulates cardiac muscle tissue growth relationship: RO:0002213 GO:0055017 ! positively regulates cardiac muscle tissue growth [Term] id: GO:0055024 name: regulation of cardiac muscle tissue development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac muscle tissue development." [GOC:vk] synonym: "regulation of heart muscle development" EXACT [] is_a: GO:0016202 ! regulation of striated muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048738 ! regulates (processual) cardiac muscle tissue development relationship: RO:0002211 GO:0048738 ! regulates (processual) cardiac muscle tissue development [Term] id: GO:0055025 name: positive regulation of cardiac muscle tissue development namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle tissue development." [GOC:vk] synonym: "positive regulation of heart muscle development" EXACT [] synonym: "up regulation of cardiac muscle development" EXACT [] synonym: "up-regulation of cardiac muscle development" EXACT [] synonym: "upregulation of cardiac muscle development" EXACT [] is_a: GO:0045844 ! positive regulation of striated muscle tissue development is_a: GO:0055024 ! regulation of cardiac muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0048738 ! positively regulates cardiac muscle tissue development relationship: RO:0002213 GO:0048738 ! positively regulates cardiac muscle tissue development [Term] id: GO:0055026 name: negative regulation of cardiac muscle tissue development namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle tissue development." [GOC:vk] synonym: "down regulation of cardiac muscle development" EXACT [] synonym: "down-regulation of cardiac muscle development" EXACT [] synonym: "downregulation of cardiac muscle development" EXACT [] synonym: "negative regulation of heart muscle development" EXACT [] is_a: GO:0045843 ! negative regulation of striated muscle tissue development is_a: GO:0055024 ! regulation of cardiac muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048738 ! negatively regulates cardiac muscle tissue development relationship: RO:0002212 GO:0048738 ! negatively regulates cardiac muscle tissue development [Term] id: GO:0055057 name: neuroblast division namespace: biological_process def: "The process resulting in the physical partitioning and separation of a neuroblast into daughter cells. A neuroblast is any cell that will divide and give rise to a neuron." [PMID:11163136, PMID:11250167] synonym: "neuroblast cell division" EXACT [] is_a: GO:0051301 ! cell division intersection_of: GO:0051301 ! cell division intersection_of: RO:0004009 CL:0000031 ! has primary input neuroblast (sensu Vertebrata) relationship: BFO:0000050 GO:0007405 ! part of neuroblast proliferation relationship: RO:0004009 CL:0000031 ! has primary input neuroblast (sensu Vertebrata) [Term] id: GO:0055059 name: asymmetric neuroblast division namespace: biological_process def: "The process resulting in the physical partitioning and separation of a neuroblast into two daughter cells with different developmental potentials." [GOC:dph] is_a: GO:0008356 ! asymmetric cell division is_a: GO:0045165 ! cell fate commitment is_a: GO:0055057 ! neuroblast division intersection_of: GO:0008356 ! asymmetric cell division intersection_of: RO:0004009 CL:0000031 ! has primary input neuroblast (sensu Vertebrata) [Term] id: GO:0055085 name: transmembrane transport namespace: biological_process def: "The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other." [GOC:dph, GOC:jid] synonym: "membrane transport" EXACT [] is_a: GO:0006810 ! transport is_a: GO:0009987 ! cellular process intersection_of: GO:0006810 ! transport intersection_of: RO:0002342 GO:0016020 ! results in transport across membrane relationship: RO:0002342 GO:0016020 ! results in transport across membrane creation_date: 2015-10-21T13:22:47Z [Term] id: GO:0055086 name: nucleobase-containing small molecule metabolic process namespace: biological_process def: "The cellular chemical reactions and pathways involving a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide." [GOC:vw] synonym: "nucleobase, nucleoside and nucleotide metabolism" EXACT [] is_a: GO:0006139 ! nucleobase-containing compound metabolic process is_a: GO:0044281 ! small molecule metabolic process [Term] id: GO:0055107 name: Golgi to secretory granule transport namespace: biological_process def: "The directed movement of proteins from the Golgi to a secretory granule. The secretory granule is a membrane-bounded particle, usually protein, formed in the granular endoplasmic reticulum and the Golgi complex." [GOC:curators] is_a: GO:0046907 ! intracellular transport intersection_of: GO:0006810 ! transport intersection_of: BFO:0000066 GO:0005737 ! occurs in cytoplasm intersection_of: RO:0002338 GO:0005794 ! has target start location Golgi apparatus intersection_of: RO:0002339 GO:0030141 ! has target end location secretory granule relationship: BFO:0000066 GO:0005737 ! occurs in cytoplasm relationship: RO:0002338 GO:0005794 ! has target start location Golgi apparatus relationship: RO:0002339 GO:0030141 ! has target end location secretory granule [Term] id: GO:0055108 name: Golgi to transport vesicle transport namespace: biological_process def: "The directed movement of proteins from the Golgi to a transport vesicle. Continuously secreted proteins are sorted into transport vesicles that fuse with the plasma membrane, releasing their contents by exocytosis." [GOC:jid] is_a: GO:0046907 ! intracellular transport intersection_of: GO:0006810 ! transport intersection_of: BFO:0000066 GO:0005737 ! occurs in cytoplasm intersection_of: RO:0002338 GO:0005794 ! has target start location Golgi apparatus intersection_of: RO:0002339 GO:0030133 ! has target end location transport vesicle relationship: BFO:0000050 GO:0048193 ! part of Golgi vesicle transport relationship: BFO:0000066 GO:0005737 ! occurs in cytoplasm relationship: RO:0002338 GO:0005794 ! has target start location Golgi apparatus relationship: RO:0002339 GO:0030133 ! has target end location transport vesicle [Term] id: GO:0055111 name: ingression involved in gastrulation with mouth forming second namespace: biological_process def: "The migration of individual cells into the embryo involved in deuterostomic gastrulation." [ISBN:0878932437] is_a: GO:0042074 ! cell migration involved in gastrulation intersection_of: GO:0001667 ! ameboidal-type cell migration intersection_of: BFO:0000050 GO:0001702 ! part of gastrulation with mouth forming second relationship: BFO:0000050 GO:0001702 ! part of gastrulation with mouth forming second [Term] id: GO:0055117 name: regulation of cardiac muscle contraction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac muscle contraction." [GOC:ecd] is_a: GO:0006942 ! regulation of striated muscle contraction is_a: GO:0008016 ! regulation of heart contraction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060048 ! regulates (processual) cardiac muscle contraction relationship: RO:0002211 GO:0060048 ! regulates (processual) cardiac muscle contraction [Term] id: GO:0055118 name: negative regulation of cardiac muscle contraction namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle contraction." [GOC:ecd] is_a: GO:0045822 ! negative regulation of heart contraction is_a: GO:0045988 ! negative regulation of striated muscle contraction is_a: GO:0055117 ! regulation of cardiac muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060048 ! negatively regulates cardiac muscle contraction relationship: RO:0002212 GO:0060048 ! negatively regulates cardiac muscle contraction [Term] id: GO:0055123 name: digestive system development namespace: biological_process def: "The process whose specific outcome is the progression of the digestive system over time, from its formation to the mature structure. The digestive system is the entire structure in which digestion takes place. Digestion is all of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." [GOC:jid] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001007 ! results in development of digestive system relationship: RO:0002296 UBERON:0001007 ! results in development of digestive system [Term] id: GO:0060008 name: Sertoli cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules." [GOC:dph] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0030855 ! epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000216 ! results in acquisition of features of Sertoli cell relationship: BFO:0000050 GO:0008584 ! part of male gonad development relationship: RO:0002315 CL:0000216 ! results in acquisition of features of Sertoli cell [Term] id: GO:0060009 name: Sertoli cell development namespace: biological_process def: "The process whose specific outcome is the progression of a Sertoli cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a Sertoli cell fate." [GOC:dph] is_a: GO:0002064 ! epithelial cell development is_a: GO:0003006 ! developmental process involved in reproduction intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000216 ! results in development of Sertoli cell relationship: BFO:0000050 GO:0060008 ! part of Sertoli cell differentiation relationship: RO:0002296 CL:0000216 ! results in development of Sertoli cell [Term] id: GO:0060011 name: Sertoli cell proliferation namespace: biological_process def: "The multiplication or reproduction of Sertoli cells, resulting in the expansion of the Sertoli cell population. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules." [GOC:dph] is_a: GO:0022414 ! reproductive process is_a: GO:0050673 ! epithelial cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000216 ! acts on population of Sertoli cell relationship: BFO:0000050 GO:0008584 ! part of male gonad development relationship: RO:0012003 CL:0000216 ! acts on population of Sertoli cell [Term] id: GO:0060021 name: roof of mouth development namespace: biological_process def: "The biological process whose specific outcome is the progression of the roof of the mouth from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The roof of the mouth is the partition that separates the nasal and oral cavities." [GOC:dph, ISBN:0721662544] synonym: "palatum development" EXACT [ISBN:0721662544] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0007375 ! results in development of roof of mouth relationship: RO:0002296 UBERON:0007375 ! results in development of roof of mouth [Term] id: GO:0060037 name: pharyngeal system development namespace: biological_process def: "The process whose specific outcome is the progression of the pharyngeal system over time, from its formation to the mature structure. The pharyngeal system is a transient embryonic complex that is specific to vertebrates. It comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the stucture it contributes to are forming: the thymus, thyroid, parathyroids, maxilla, mandible, aortic arch, cardiac outflow tract, external and middle ear." [GOC:dph] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0008814 ! results in development of pharyngeal arch system relationship: BFO:0000050 GO:0043009 ! part of chordate embryonic development relationship: RO:0002296 UBERON:0008814 ! results in development of pharyngeal arch system [Term] id: GO:0060038 name: cardiac muscle cell proliferation namespace: biological_process def: "The expansion of a cardiac muscle cell population by cell division." [GOC:dph, GOC:rph, PMID:11161571] synonym: "cardiac myocyte proliferation" EXACT [] synonym: "heart muscle cell proliferation" EXACT [] is_a: GO:0014855 ! striated muscle cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000746 ! acts on population of cardiac muscle cell relationship: BFO:0000050 GO:0055017 ! part of cardiac muscle tissue growth relationship: RO:0012003 CL:0000746 ! acts on population of cardiac muscle cell [Term] id: GO:0060039 name: pericardium development namespace: biological_process def: "The process whose specific outcome is the progression of the pericardium over time, from its formation to the mature structure. The pericardium is a double-walled sac that contains the heart and the roots of the aorta, vena cava and the pulmonary artery." [GOC:dph, GOC:rph, PMID:15138308, PMID:16376438] is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002407 ! results in development of pericardium relationship: BFO:0000050 GO:0007507 ! part of heart development relationship: RO:0002296 UBERON:0002407 ! results in development of pericardium [Term] id: GO:0060041 name: retina development in camera-type eye namespace: biological_process def: "The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates." [GOC:bf, GOC:dph, ISBN:0815340729] synonym: "retina development in camera-style eye" EXACT [] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: BFO:0000050 GO:0043010 ! part of camera-type eye development intersection_of: RO:0002296 UBERON:0000966 ! results in development of retina relationship: BFO:0000050 GO:0043010 ! part of camera-type eye development relationship: RO:0002296 UBERON:0000966 ! results in development of retina [Term] id: GO:0060042 name: retina morphogenesis in camera-type eye namespace: biological_process def: "The process in which the anatomical structure of the retina is generated and organized." [GOC:bf, GOC:dph, GOC:mtg_sensu] synonym: "retina morphogenesis in camera-style eye" EXACT [] synonym: "retinogenesis" EXACT [] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000966 ! results in morphogenesis of retina relationship: BFO:0000050 GO:0048593 ! part of camera-type eye morphogenesis relationship: BFO:0000050 GO:0060041 ! part of retina development in camera-type eye relationship: RO:0002298 UBERON:0000966 ! results in morphogenesis of retina [Term] id: GO:0060043 name: regulation of cardiac muscle cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac muscle cell proliferation." [GOC:dph, GOC:rph] synonym: "regulation of heart muscle cell proliferation" EXACT [] is_a: GO:0042127 ! regulation of cell population proliferation is_a: GO:0055021 ! regulation of cardiac muscle tissue growth intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060038 ! regulates (processual) cardiac muscle cell proliferation relationship: RO:0002211 GO:0060038 ! regulates (processual) cardiac muscle cell proliferation [Term] id: GO:0060044 name: negative regulation of cardiac muscle cell proliferation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell proliferation." [GOC:dph, GOC:rph] synonym: "negative regulation of heart muscle cell proliferation" EXACT [] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0055022 ! negative regulation of cardiac muscle tissue growth is_a: GO:0060043 ! regulation of cardiac muscle cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060038 ! negatively regulates cardiac muscle cell proliferation relationship: RO:0002212 GO:0060038 ! negatively regulates cardiac muscle cell proliferation [Term] id: GO:0060045 name: positive regulation of cardiac muscle cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cardiac muscle cell proliferation." [GOC:dph, GOC:rph] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0055023 ! positive regulation of cardiac muscle tissue growth is_a: GO:0060043 ! regulation of cardiac muscle cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060038 ! positively regulates cardiac muscle cell proliferation relationship: RO:0002213 GO:0060038 ! positively regulates cardiac muscle cell proliferation [Term] id: GO:0060047 name: heart contraction namespace: biological_process def: "The multicellular organismal process in which the heart decreases in volume in a characteristic way to propel blood through the body." [GOC:dph] synonym: "heart beating" EXACT [] is_a: GO:0003015 ! heart process relationship: BFO:0000050 GO:0008015 ! part of blood circulation [Term] id: GO:0060048 name: cardiac muscle contraction namespace: biological_process def: "Muscle contraction of cardiac muscle tissue." [GOC:dph] synonym: "heart muscle contraction" EXACT [] is_a: GO:0006941 ! striated muscle contraction intersection_of: GO:0006936 ! muscle contraction intersection_of: BFO:0000066 UBERON:0001133 ! occurs in cardiac muscle tissue relationship: BFO:0000050 GO:0060047 ! part of heart contraction relationship: BFO:0000066 UBERON:0001133 ! occurs in cardiac muscle tissue [Term] id: GO:0060065 name: uterus development namespace: biological_process def: "The reproductive developmental process whose specific outcome is the progression of the uterus over time, from its formation to the mature structure." [GOC:dph, GOC:ebc] is_a: GO:0048513 ! animal organ development is_a: GO:0048608 ! reproductive structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000995 ! results in development of uterus relationship: RO:0002296 UBERON:0000995 ! results in development of uterus [Term] id: GO:0060066 name: oviduct development namespace: biological_process def: "The reproductive developmental process whose specific outcome is the progression of an oviduct over time, from its formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism." [GOC:dph, GOC:ebc, http://www.thefreedictionary.com/oviduct] is_a: GO:0035295 ! tube development is_a: GO:0048608 ! reproductive structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003889 ! results in development of fallopian tube relationship: RO:0002296 UBERON:0003889 ! results in development of fallopian tube [Term] id: GO:0060073 name: micturition namespace: biological_process def: "The regulation of body fluids process in which parasympathetic nerves stimulate the bladder wall muscle to contract and expel urine from the body." [GOC:dph] synonym: "urination" EXACT [] synonym: "urine voiding" EXACT [] xref: Wikipedia:Urination is_a: GO:0003014 ! renal system process is_a: GO:0007588 ! excretion [Term] id: GO:0060083 name: smooth muscle contraction involved in micturition namespace: biological_process def: "The process leading to shortening and/or development of tension in the urinary bladder smooth muscle tissue involved in the expulsion urine from the body." [GOC:dph, PMID:15827347] is_a: GO:0014832 ! urinary bladder smooth muscle contraction intersection_of: GO:0006939 ! smooth muscle contraction intersection_of: BFO:0000050 GO:0060073 ! part of micturition relationship: BFO:0000050 GO:0060073 ! part of micturition [Term] id: GO:0060084 name: synaptic transmission involved in micturition namespace: biological_process def: "The process of communication from a neuron to a smooth muscle in the bladder that contributes to the expulsion of urine from the body." [GOC:dph, PMID:15827347] is_a: GO:0007274 ! neuromuscular synaptic transmission intersection_of: GO:0007268 ! chemical synaptic transmission intersection_of: BFO:0000050 GO:0060073 ! part of micturition relationship: BFO:0000050 GO:0060073 ! part of micturition [Term] id: GO:0060096 name: serotonin secretion, neurotransmission namespace: biological_process def: "The regulated release of serotonin by a cell, in which released serotonin acts as a neurotransmitter." [GOC:dph] is_a: GO:0001820 ! serotonin secretion is_a: GO:0007269 ! neurotransmitter secretion intersection_of: GO:0007269 ! neurotransmitter secretion intersection_of: RO:0004009 CHEBI:350546 ! has primary input serotonin(1+) [Term] id: GO:0060135 name: maternal process involved in female pregnancy namespace: biological_process def: "A reproductive process occurring in the mother that allows an embryo or fetus to develop within it." [GOC:dph] is_a: GO:0048609 ! multicellular organismal reproductive process relationship: BFO:0000050 GO:0007565 ! part of female pregnancy [Term] id: GO:0060136 name: embryonic process involved in female pregnancy namespace: biological_process def: "A reproductive process occurring in the embryo or fetus that allows the embryo or fetus to develop within the mother." [GOC:dph] is_a: GO:0048609 ! multicellular organismal reproductive process intersection_of: GO:0022414 ! reproductive process intersection_of: BFO:0000050 GO:0007565 ! part of female pregnancy intersection_of: BFO:0000050 GO:0009790 ! part of embryo development relationship: BFO:0000050 GO:0007565 ! part of female pregnancy relationship: BFO:0000050 GO:0009792 ! part of embryo development ending in birth or egg hatching [Term] id: GO:0060142 name: regulation of syncytium formation by plasma membrane fusion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." [GOC:dph] is_a: GO:0050793 ! regulation of developmental process is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0000768 ! regulates (processual) syncytium formation by plasma membrane fusion relationship: RO:0002211 GO:0000768 ! regulates (processual) syncytium formation by plasma membrane fusion [Term] id: GO:0060143 name: positive regulation of syncytium formation by plasma membrane fusion namespace: biological_process def: "Any process that increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." [GOC:dph] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051130 ! positive regulation of cellular component organization is_a: GO:0060142 ! regulation of syncytium formation by plasma membrane fusion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0000768 ! positively regulates syncytium formation by plasma membrane fusion relationship: RO:0002213 GO:0000768 ! positively regulates syncytium formation by plasma membrane fusion [Term] id: GO:0060157 name: urinary bladder development namespace: biological_process def: "The process whose specific outcome is the progression of the urinary bladder over time, from its formation to the mature structure. The urinary bladder is an elastic, muscular sac situated in the anterior part of the pelvic cavity in which urine collects before excretion." [GOC:dph, GOC:ln, GOC:mr, PMID:11768524, PMID:18276178, PMID:538956] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001255 ! results in development of urinary bladder relationship: BFO:0000050 GO:0072001 ! part of renal system development relationship: RO:0002296 UBERON:0001255 ! results in development of urinary bladder [Term] id: GO:0060170 name: ciliary membrane namespace: cellular_component def: "The portion of the plasma membrane surrounding a cilium." [GOC:cilia, GOC:dph, GOC:rph] synonym: "cilial membrane" EXACT [] synonym: "cilium membrane" EXACT [] is_a: GO:0031253 ! cell projection membrane is_a: GO:0098588 ! bounding membrane of organelle intersection_of: GO:0016020 ! membrane intersection_of: RO:0002007 GO:0005929 ! bounding layer of cilium relationship: RO:0002007 GO:0005929 ! bounding layer of cilium [Term] id: GO:0060173 name: limb development namespace: biological_process def: "The process whose specific outcome is the progression of a limb over time, from its formation to the mature structure. A limb is an appendage of an animal used for locomotion or grasping. Examples include legs, arms or some types of fin." [GOC:dgh, GOC:dph, PMID:11487378] synonym: "paired limb/fin development" EXACT [] xref: Wikipedia:Limb_development is_a: GO:0048736 ! appendage development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004708 ! results in development of paired limb/fin relationship: RO:0002296 UBERON:0004708 ! results in development of paired limb/fin [Term] id: GO:0060214 name: endocardium formation namespace: biological_process def: "Formation of the endocardium of the heart. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers." [GOC:bf, GOC:dph, PMID:17722983] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0002165 ! results in formation of anatomical entity endocardium relationship: BFO:0000050 GO:0003160 ! part of endocardium morphogenesis relationship: RO:0002297 UBERON:0002165 ! results in formation of anatomical entity endocardium [Term] id: GO:0060218 name: hematopoietic stem cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a hematopoietic stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [GOC:bf, GOC:BHF, GOC:dph, GOC:rl, PMID:15378083] synonym: "haematopoietic stem cell differentiation" EXACT [] synonym: "haemopoietic stem cell differentiation" EXACT [] synonym: "hemopoietic stem cell differentiation" EXACT [] is_a: GO:0002244 ! hematopoietic progenitor cell differentiation is_a: GO:0048863 ! stem cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000037 ! results in acquisition of features of hematopoietic stem cell relationship: RO:0002315 CL:0000037 ! results in acquisition of features of hematopoietic stem cell [Term] id: GO:0060219 name: camera-type eye photoreceptor cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell in a camera-type eye." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0001754 ! eye photoreceptor cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0010009 ! results in acquisition of features of camera-type eye photoreceptor cell relationship: BFO:0000050 GO:0003407 ! part of neural retina development relationship: BFO:0000050 GO:0060042 ! part of retina morphogenesis in camera-type eye relationship: RO:0002315 CL:0010009 ! results in acquisition of features of camera-type eye photoreceptor cell [Term] id: GO:0060221 name: retinal rod cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized features of a retinal rod cell." [GOC:dph] is_a: GO:0060219 ! camera-type eye photoreceptor cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000604 ! results in acquisition of features of retinal rod cell relationship: RO:0002315 CL:0000604 ! results in acquisition of features of retinal rod cell [Term] id: GO:0060231 name: mesenchymal to epithelial transition namespace: biological_process def: "A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell." [GOC:ascb_2009, GOC:dph, GOC:tb] synonym: "epithelial cell differentiation from mesenchymal cell" EXACT [GOC:BHF, GOC:dph, GOC:rl] synonym: "mesenchymal-epithelial transition" EXACT [GOC:dph] is_a: GO:0030855 ! epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000066 ! results in acquisition of features of epithelial cell intersection_of: RO:0004009 CL:0008019 ! has primary input mesenchymal cell relationship: RO:0004009 CL:0008019 ! has primary input mesenchymal cell [Term] id: GO:0060251 name: regulation of glial cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of glial cell proliferation." [GOC:dph, GOC:tb] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0014009 ! regulates (processual) glial cell proliferation relationship: RO:0002211 GO:0014009 ! regulates (processual) glial cell proliferation [Term] id: GO:0060252 name: positive regulation of glial cell proliferation namespace: biological_process def: "Any process that activates or increases the rate or extent of glial cell proliferation." [GOC:dph, GOC:sl, GOC:tb] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0014015 ! positive regulation of gliogenesis is_a: GO:0060251 ! regulation of glial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0014009 ! positively regulates glial cell proliferation relationship: RO:0002213 GO:0014009 ! positively regulates glial cell proliferation [Term] id: GO:0060253 name: negative regulation of glial cell proliferation namespace: biological_process def: "Any process that stops or decreases the rate or extent of glial cell proliferation." [GOC:dph, GOC:sl, GOC:tb] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0014014 ! negative regulation of gliogenesis is_a: GO:0060251 ! regulation of glial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0014009 ! negatively regulates glial cell proliferation relationship: RO:0002212 GO:0014009 ! negatively regulates glial cell proliferation [Term] id: GO:0060255 name: regulation of macromolecule metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:dph, GOC:tb] is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0043170 ! regulates (processual) macromolecule metabolic process relationship: RO:0002211 GO:0043170 ! regulates (processual) macromolecule metabolic process [Term] id: GO:0060271 name: cilium assembly namespace: biological_process def: "The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole." [GOC:BHF, GOC:cilia, GOC:dph, GOC:kmv, GOC:pr, GOC:vw, ISBN:0198506732, PMID:13978319, PMID:27350441, Reactome:R-HSA-5617833.2] synonym: "ciliogenesis" EXACT [] synonym: "cilium formation" EXACT [] synonym: "microtubule-based flagellum assembly" EXACT [] xref: Reactome:R-HSA-5617833.2 is_a: GO:0044782 ! cilium organization is_a: GO:0070925 ! organelle assembly is_a: GO:0120031 ! plasma membrane bounded cell projection assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0005929 ! results in assembly of cilium relationship: BFO:0000051 GO:0035082 ! has part axoneme assembly relationship: BFO:0000051 GO:0035735 ! has part intraciliary transport involved in cilium assembly relationship: BFO:0000051 GO:0061512 ! has part protein localization to cilium relationship: BFO:0000051 GO:0097712 ! has part vesicle targeting, trans-Golgi to periciliary membrane compartment relationship: BFO:0000051 GO:1905349 ! has part ciliary transition zone assembly relationship: RO:0002162 NCBITaxon:2759 {all_only="true"} ! in taxon Eukaryota relationship: RO:0002224 GO:0097711 ! starts with ciliary basal body-plasma membrane docking relationship: RO:0002588 GO:0005929 ! results in assembly of cilium [Term] id: GO:0060281 name: regulation of oocyte development namespace: biological_process def: "Any process that modulates the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." [GOC:dph, GOC:tb, PMID:2394318] is_a: GO:1905879 ! regulation of oogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048599 ! regulates (processual) oocyte development relationship: RO:0002211 GO:0048599 ! regulates (processual) oocyte development [Term] id: GO:0060282 name: positive regulation of oocyte development namespace: biological_process def: "Any process that increases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." [GOC:dph, GOC:tb] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0060281 ! regulation of oocyte development is_a: GO:2000243 ! positive regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0048599 ! positively regulates oocyte development relationship: RO:0002213 GO:0048599 ! positively regulates oocyte development [Term] id: GO:0060283 name: negative regulation of oocyte development namespace: biological_process def: "Any process that decreases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." [GOC:dph, GOC:tb] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0060281 ! regulation of oocyte development is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048599 ! negatively regulates oocyte development relationship: RO:0002212 GO:0048599 ! negatively regulates oocyte development [Term] id: GO:0060284 name: regulation of cell development namespace: biological_process def: "Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." [GOC:dph, GOC:tb] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048468 ! regulates (processual) cell development relationship: RO:0002211 GO:0048468 ! regulates (processual) cell development [Term] id: GO:0060285 name: cilium-dependent cell motility namespace: biological_process def: "Cell motility due to the motion of one or more eukaryotic cilia. A eukaryotic cilium is a specialized organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole." [GOC:cilia, GOC:dgh, GOC:dph, GOC:krc, GOC:mlg, GOC:mtg_cambridge_2013] synonym: "cilium cell motility" EXACT [] synonym: "microtubule-based flagellar cell motility" EXACT [] is_a: GO:0001539 ! cilium or flagellum-dependent cell motility relationship: BFO:0000051 GO:0003341 ! has part cilium movement [Term] id: GO:0060294 name: cilium movement involved in cell motility namespace: biological_process def: "Movement of cilia mediated by motor proteins that contributes to the movement of a cell." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0003341 ! cilium movement intersection_of: GO:0003341 ! cilium movement intersection_of: BFO:0000050 GO:0048870 ! part of cell motility relationship: BFO:0000050 GO:0060285 ! part of cilium-dependent cell motility [Term] id: GO:0060295 name: regulation of cilium movement involved in cell motility namespace: biological_process def: "Any process that modulates the rate frequency or extent of cilium movement involved in ciliary motility." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0003352 ! regulation of cilium movement is_a: GO:1902019 ! regulation of cilium-dependent cell motility intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060294 ! regulates (processual) cilium movement involved in cell motility relationship: RO:0002211 GO:0060294 ! regulates (processual) cilium movement involved in cell motility [Term] id: GO:0060297 name: regulation of sarcomere organization namespace: biological_process def: "Any process that modulates the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." [GOC:BHF, GOC:dph, GOC:tb] synonym: "regulation of sarcomere organisation" EXACT [GOC:mah] is_a: GO:0110020 ! regulation of actomyosin structure organization is_a: GO:1902903 ! regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0045214 ! regulates (processual) sarcomere organization relationship: RO:0002211 GO:0045214 ! regulates (processual) sarcomere organization [Term] id: GO:0060298 name: positive regulation of sarcomere organization namespace: biological_process def: "Any process that increases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." [GOC:BHF, GOC:dph, GOC:tb] synonym: "positive regulation of sarcomere organisation" EXACT [GOC:mah] is_a: GO:0051155 ! positive regulation of striated muscle cell differentiation is_a: GO:0051495 ! positive regulation of cytoskeleton organization is_a: GO:0060297 ! regulation of sarcomere organization is_a: GO:1902905 ! positive regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0045214 ! positively regulates sarcomere organization relationship: RO:0002213 GO:0045214 ! positively regulates sarcomere organization [Term] id: GO:0060299 name: negative regulation of sarcomere organization namespace: biological_process def: "Any process that decreases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." [GOC:BHF, GOC:dph, GOC:tb] synonym: "negative regulation of sarcomere organisation" EXACT [GOC:mah] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0051494 ! negative regulation of cytoskeleton organization is_a: GO:0060297 ! regulation of sarcomere organization is_a: GO:1902116 ! negative regulation of organelle assembly is_a: GO:1902904 ! negative regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0045214 ! negatively regulates sarcomere organization relationship: RO:0002212 GO:0045214 ! negatively regulates sarcomere organization [Term] id: GO:0060322 name: head development namespace: biological_process def: "The biological process whose specific outcome is the progression of a head from an initial condition to its mature state. The head is the anterior-most division of the body." [GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000033 ! results in development of head relationship: RO:0002296 UBERON:0000033 ! results in development of head [Term] id: GO:0060323 name: head morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the head are generated and organized. The head is the anterior-most division of the body." [GOC:dph] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000033 ! results in morphogenesis of head relationship: BFO:0000050 GO:0010171 ! part of body morphogenesis relationship: BFO:0000050 GO:0060322 ! part of head development relationship: RO:0002298 UBERON:0000033 ! results in morphogenesis of head [Term] id: GO:0060324 name: face development namespace: biological_process def: "The biological process whose specific outcome is the progression of a face from an initial condition to its mature state. The face is the ventral division of the head." [GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001456 ! results in development of face relationship: BFO:0000050 GO:0060322 ! part of head development relationship: RO:0002296 UBERON:0001456 ! results in development of face [Term] id: GO:0060325 name: face morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the face are generated and organized. The face is the ventral division of the head." [GOC:dph] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001456 ! results in morphogenesis of face relationship: BFO:0000050 GO:0060323 ! part of head morphogenesis relationship: BFO:0000050 GO:0060324 ! part of face development relationship: RO:0002298 UBERON:0001456 ! results in morphogenesis of face [Term] id: GO:0060341 name: regulation of cellular localization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a process in which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell." [GOC:dph, GOC:tb] synonym: "regulation of cellular localisation" EXACT [GOC:mah] is_a: GO:0032879 ! regulation of localization is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0051641 ! regulates (processual) cellular localization relationship: RO:0002211 GO:0051641 ! regulates (processual) cellular localization [Term] id: GO:0060343 name: trabecula formation namespace: biological_process def: "The process of creating a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue." [GOC:dph] synonym: "trabeculation" EXACT [GOC:dph] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0000440 ! results in formation of anatomical entity trabecula relationship: BFO:0000050 GO:0009887 ! part of animal organ morphogenesis relationship: BFO:0000050 GO:0061383 ! part of trabecula morphogenesis relationship: RO:0002297 UBERON:0000440 ! results in formation of anatomical entity trabecula [Term] id: GO:0060344 name: liver trabecula formation namespace: biological_process def: "The process of creating a trabecula in the liver. A trabecula is a tissue element in the form of a small beam, strut or rod." [GOC:dph] synonym: "liver trabeculation" EXACT [GOC:dph] is_a: GO:0060343 ! trabecula formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0010183 ! results in formation of anatomical entity liver trabecula relationship: BFO:0000050 GO:0001889 ! part of liver development relationship: RO:0002297 UBERON:0010183 ! results in formation of anatomical entity liver trabecula [Term] id: GO:0060345 name: spleen trabecula formation namespace: biological_process def: "The process of creating a trabecula in the spleen. A trabecula is a tissue element in the form of a small beam, strut or rod." [GOC:dph] synonym: "spleen trabeculation" EXACT [GOC:dph] is_a: GO:0060343 ! trabecula formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0001265 ! results in formation of anatomical entity trabecula of spleen relationship: BFO:0000050 GO:0048536 ! part of spleen development relationship: RO:0002297 UBERON:0001265 ! results in formation of anatomical entity trabecula of spleen [Term] id: GO:0060347 name: heart trabecula formation namespace: biological_process def: "The process of creating a trabecula in the heart. A trabecula is a tissue element in the form of a small beam, strut or rod." [GOC:dph] synonym: "cardiac trabecula formation" EXACT [GOC:dph] synonym: "cardiac trabeculation" EXACT [GOC:dph] synonym: "heart trabeculation" EXACT [GOC:dph] is_a: GO:0060343 ! trabecula formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0002511 ! results in formation of anatomical entity trabecula carnea relationship: BFO:0000050 GO:0003206 ! part of cardiac chamber morphogenesis relationship: BFO:0000050 GO:0061384 ! part of heart trabecula morphogenesis relationship: RO:0002297 UBERON:0002511 ! results in formation of anatomical entity trabecula carnea [Term] id: GO:0060348 name: bone development namespace: biological_process def: "The process whose specific outcome is the progression of bone over time, from its formation to the mature structure. Bone is the hard skeletal connective tissue consisting of both mineral and cellular components." [GOC:dph] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048513 ! animal organ development intersection_of: RO:0002296 UBERON:0001474 ! results in development of bone element relationship: BFO:0000050 GO:0001501 ! part of skeletal system development relationship: RO:0002296 UBERON:0001474 ! results in development of bone element [Term] id: GO:0060349 name: bone morphogenesis namespace: biological_process def: "The process in which bones are generated and organized." [GOC:dph] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001474 ! results in morphogenesis of bone element relationship: BFO:0000050 GO:0048705 ! part of skeletal system morphogenesis relationship: BFO:0000050 GO:0060348 ! part of bone development relationship: RO:0002298 UBERON:0001474 ! results in morphogenesis of bone element [Term] id: GO:0060350 name: endochondral bone morphogenesis namespace: biological_process def: "The process in which bones are generated and organized as a result of the conversion of initial cartilaginous anlage into bone." [GOC:dph, PMID:11680679] is_a: GO:0060349 ! bone morphogenesis intersection_of: GO:0060349 ! bone morphogenesis intersection_of: RO:0002298 UBERON:0002513 ! results in morphogenesis of endochondral bone relationship: RO:0002298 UBERON:0002513 ! results in morphogenesis of endochondral bone [Term] id: GO:0060351 name: cartilage development involved in endochondral bone morphogenesis namespace: biological_process def: "The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones." [GOC:dph] is_a: GO:0051216 ! cartilage development intersection_of: GO:0051216 ! cartilage development intersection_of: BFO:0000050 GO:0060350 ! part of endochondral bone morphogenesis relationship: BFO:0000050 GO:0060350 ! part of endochondral bone morphogenesis [Term] id: GO:0060359 name: response to ammonium ion namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:23509267] synonym: "response to ammonia" EXACT [] is_a: GO:0010035 ! response to inorganic substance is_a: GO:1901698 ! response to nitrogen compound intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:28938 ! has primary input ammonium relationship: RO:0004009 CHEBI:28938 ! has primary input ammonium [Term] id: GO:0060379 name: cardiac muscle cell myoblast differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a cardiac myoblast. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life." [GOC:dph, GOC:tb] synonym: "myocardial precursor cell differentiation" EXACT [GOC:mtg_heart] is_a: GO:0010002 ! cardioblast differentiation is_a: GO:0045445 ! myoblast differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000513 ! results in acquisition of features of cardiac muscle myoblast relationship: RO:0002315 CL:0000513 ! results in acquisition of features of cardiac muscle myoblast [Term] id: GO:0060404 name: axonemal microtubule depolymerization namespace: biological_process def: "The removal of tubulin heterodimers from one or both ends of an axonemal microtubule. An axonemal microtubule is a microtubule in the axoneme of a cilium or flagellum; an axoneme contains nine modified doublet microtubules surrounding a pair of single microtubules." [GOC:cilia, GOC:dph, GOC:krc, GOC:tb] is_a: GO:0010938 ! cytoplasmic microtubule depolymerization is_a: GO:0061523 ! cilium disassembly intersection_of: GO:0007019 ! microtubule depolymerization intersection_of: BFO:0000066 GO:0005930 ! occurs in axoneme relationship: BFO:0000066 GO:0005930 ! occurs in axoneme [Term] id: GO:0060408 name: regulation of acetylcholine metabolic process namespace: biological_process def: "Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." [GOC:dph, GOC:tb] is_a: GO:0033238 ! regulation of amine metabolic process is_a: GO:0080090 ! regulation of primary metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0008291 ! regulates (processual) acetylcholine metabolic process relationship: RO:0002211 GO:0008291 ! regulates (processual) acetylcholine metabolic process [Term] id: GO:0060409 name: positive regulation of acetylcholine metabolic process namespace: biological_process def: "Any process that increases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." [GOC:dph, GOC:tb] is_a: GO:0033240 ! positive regulation of amine metabolic process is_a: GO:0060408 ! regulation of acetylcholine metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0008291 ! positively regulates acetylcholine metabolic process relationship: RO:0002213 GO:0008291 ! positively regulates acetylcholine metabolic process [Term] id: GO:0060410 name: negative regulation of acetylcholine metabolic process namespace: biological_process def: "Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." [GOC:dph, GOC:tb] is_a: GO:0033239 ! negative regulation of amine metabolic process is_a: GO:0060408 ! regulation of acetylcholine metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0008291 ! negatively regulates acetylcholine metabolic process relationship: RO:0002212 GO:0008291 ! negatively regulates acetylcholine metabolic process [Term] id: GO:0060411 name: cardiac septum morphogenesis namespace: biological_process def: "The process in which the anatomical structure of a cardiac septum is generated and organized. A cardiac septum is a partition that separates parts of the heart." [GOC:dph, GOC:mtg_heart] synonym: "heart septum morphogenesis" EXACT [] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002099 ! results in morphogenesis of cardiac septum relationship: BFO:0000050 GO:0003206 ! part of cardiac chamber morphogenesis relationship: BFO:0000050 GO:0003279 ! part of cardiac septum development relationship: RO:0002298 UBERON:0002099 ! results in morphogenesis of cardiac septum [Term] id: GO:0060412 name: ventricular septum morphogenesis namespace: biological_process def: "The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another." [GOC:dph] synonym: "interventricular septum morphogenesis" EXACT [GOC:dph] is_a: GO:0060411 ! cardiac septum morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002094 ! results in morphogenesis of interventricular septum relationship: BFO:0000050 GO:0003281 ! part of ventricular septum development relationship: RO:0002298 UBERON:0002094 ! results in morphogenesis of interventricular septum [Term] id: GO:0060413 name: atrial septum morphogenesis namespace: biological_process def: "The developmental process in which atrial septum is generated and organized. The atrial septum separates the upper chambers (the atria) of the heart from one another." [GOC:dph, GOC:mtg_heart] synonym: "interatrial septum morphogenesis" EXACT [GOC:dph] is_a: GO:0060411 ! cardiac septum morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002085 ! results in morphogenesis of interatrial septum relationship: BFO:0000050 GO:0003209 ! part of cardiac atrium morphogenesis relationship: BFO:0000050 GO:0003283 ! part of atrial septum development relationship: RO:0002298 UBERON:0002085 ! results in morphogenesis of interatrial septum [Term] id: GO:0060414 name: aorta smooth muscle tissue morphogenesis namespace: biological_process def: "The process in which the structure of the smooth muscle tissue surrounding the aorta is generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body." [GOC:bf, GOC:dgh, GOC:dph, Wikipedia:Aorta] is_a: GO:0060415 ! muscle tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0004178 ! results in morphogenesis of aorta smooth muscle tissue relationship: BFO:0000050 GO:0035909 ! part of aorta morphogenesis relationship: BFO:0000050 GO:0048745 ! part of smooth muscle tissue development relationship: RO:0002298 UBERON:0004178 ! results in morphogenesis of aorta smooth muscle tissue [Term] id: GO:0060415 name: muscle tissue morphogenesis namespace: biological_process def: "The process in which the anatomical structures of muscle tissue are generated and organized. Muscle tissue consists of a set of cells that are part of an organ and carry out a contractive function." [GOC:dph] is_a: GO:0048729 ! tissue morphogenesis intersection_of: GO:0048729 ! tissue morphogenesis intersection_of: RO:0002298 UBERON:0002385 ! results in morphogenesis of muscle tissue relationship: BFO:0000050 GO:0048644 ! part of muscle organ morphogenesis relationship: RO:0002298 UBERON:0002385 ! results in morphogenesis of muscle tissue [Term] id: GO:0060419 name: heart growth namespace: biological_process def: "The increase in size or mass of the heart." [GOC:dph, GOC:tb] is_a: GO:0035265 ! organ growth intersection_of: GO:0048589 ! developmental growth intersection_of: RO:0002343 UBERON:0000948 ! results in growth of heart relationship: BFO:0000050 GO:0007507 ! part of heart development relationship: RO:0002343 UBERON:0000948 ! results in growth of heart [Term] id: GO:0060420 name: regulation of heart growth namespace: biological_process def: "Any process that modulates the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart." [GOC:dph, GOC:tb] is_a: GO:0046620 ! regulation of organ growth is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060419 ! regulates (processual) heart growth relationship: RO:0002211 GO:0060419 ! regulates (processual) heart growth [Term] id: GO:0060421 name: positive regulation of heart growth namespace: biological_process def: "Any process that increases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0046622 ! positive regulation of organ growth is_a: GO:0060420 ! regulation of heart growth intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060419 ! positively regulates heart growth relationship: RO:0002213 GO:0060419 ! positively regulates heart growth [Term] id: GO:0060425 name: lung morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the lung are generated and organized." [GOC:dph] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002048 ! results in morphogenesis of lung relationship: BFO:0000050 GO:0030324 ! part of lung development relationship: RO:0002298 UBERON:0002048 ! results in morphogenesis of lung [Term] id: GO:0060426 name: lung vasculature development namespace: biological_process def: "The biological process whose specific outcome is the progression of a lung vasculature from an initial condition to its mature state. This process begins with the formation of the lung vasculature and ends with the mature structure. The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs." [GOC:dph, GOC:mtg_lung] synonym: "pulmonary vasculature development" EXACT [GOC:dph, GOC:mtg_lung] is_a: GO:0001944 ! vasculature development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000102 ! results in development of lung vasculature relationship: BFO:0000050 GO:0030324 ! part of lung development relationship: RO:0002296 UBERON:0000102 ! results in development of lung vasculature [Term] id: GO:0060427 name: lung connective tissue development namespace: biological_process def: "The biological process whose specific outcome is the progression of lung connective tissue from an initial condition to its mature state. This process begins with the formation of lung connective tissue and ends with the mature structure. The lung connective tissue is a material made up of fibers forming a framework and support structure for the lungs." [GOC:dph, GOC:mtg_lung] synonym: "pulmonary connective tissue development" EXACT [] is_a: GO:0061448 ! connective tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000114 ! results in development of lung connective tissue relationship: BFO:0000050 GO:0030324 ! part of lung development relationship: RO:0002296 UBERON:0000114 ! results in development of lung connective tissue [Term] id: GO:0060428 name: lung epithelium development namespace: biological_process def: "The biological process whose specific outcome is the progression of the lung epithelium from an initial condition to its mature state. This process begins with the formation of lung epithelium and ends with the mature structure. The lung epithelium is the specialized epithelium that lines the inside of the lung." [GOC:dph, GOC:mtg_lung] synonym: "pulmonary epithelium development" EXACT [GOC:dph, GOC:mtg_lung] is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000115 ! results in development of lung epithelium relationship: BFO:0000050 GO:0030324 ! part of lung development relationship: RO:0002296 UBERON:0000115 ! results in development of lung epithelium [Term] id: GO:0060429 name: epithelium development namespace: biological_process def: "The process whose specific outcome is the progression of an epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure." [GOC:dph, GOC:mtg_lung] is_a: GO:0009888 ! tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000483 ! results in development of epithelium relationship: RO:0002296 UBERON:0000483 ! results in development of epithelium [Term] id: GO:0060431 name: primary lung bud formation namespace: biological_process def: "The morphogenetic process in which the foregut region specified to become the lung forms the initial left and right buds." [GOC:dph, GOC:mtg_lung] synonym: "lung formation" EXACT [GOC:dph] is_a: GO:0016331 ! morphogenesis of embryonic epithelium is_a: GO:0048645 ! animal organ formation is_a: GO:0060441 ! epithelial tube branching involved in lung morphogenesis is_a: GO:0060572 ! morphogenesis of an epithelial bud intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0002048 ! results in formation of anatomical entity lung relationship: RO:0002297 UBERON:0002048 ! results in formation of anatomical entity lung [Term] id: GO:0060437 name: lung growth namespace: biological_process def: "The increase in size or mass of a lung. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax." [GOC:dph] is_a: GO:0035265 ! organ growth intersection_of: GO:0048589 ! developmental growth intersection_of: RO:0002343 UBERON:0002048 ! results in growth of lung relationship: BFO:0000050 GO:0030324 ! part of lung development relationship: RO:0002343 UBERON:0002048 ! results in growth of lung [Term] id: GO:0060438 name: trachea development namespace: biological_process def: "The process whose specific outcome is the progression of a trachea over time, from its formation to the mature structure. The trachea is the portion of the airway that attaches to the bronchi as it branches." [GOC:dph] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001005 ! results in development of respiratory airway relationship: BFO:0000050 GO:0060541 ! part of respiratory system development relationship: RO:0002296 UBERON:0001005 ! results in development of respiratory airway [Term] id: GO:0060439 name: trachea morphogenesis namespace: biological_process def: "The process in which a trachea is generated and organized. The trachea is the portion of the airway that attaches to the bronchi as it branches." [GOC:dph] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001005 ! results in morphogenesis of respiratory airway relationship: BFO:0000050 GO:0060438 ! part of trachea development relationship: RO:0002298 UBERON:0001005 ! results in morphogenesis of respiratory airway [Term] id: GO:0060440 name: trachea formation namespace: biological_process def: "The process pertaining to the initial formation of a trachea from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the trachea is recognizable. The trachea is the portion of the airway that attaches to the bronchi as it branches." [GOC:dph] is_a: GO:0048645 ! animal organ formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0001005 ! results in formation of anatomical entity respiratory airway relationship: BFO:0000050 GO:0060439 ! part of trachea morphogenesis relationship: RO:0002297 UBERON:0001005 ! results in formation of anatomical entity respiratory airway [Term] id: GO:0060441 name: epithelial tube branching involved in lung morphogenesis namespace: biological_process def: "The process in which a highly ordered sequence of patterning events generates the branched epithelial tubes of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units." [GOC:dph, GOC:mtg_lung] synonym: "lung branching morphogenesis" EXACT [GOC:dph] is_a: GO:0048754 ! branching morphogenesis of an epithelial tube intersection_of: GO:0048754 ! branching morphogenesis of an epithelial tube intersection_of: BFO:0000050 GO:0060425 ! part of lung morphogenesis relationship: BFO:0000050 GO:0060425 ! part of lung morphogenesis [Term] id: GO:0060450 name: positive regulation of hindgut contraction namespace: biological_process def: "Any process that increases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine." [GOC:dph, GOC:tb] is_a: GO:0043134 ! regulation of hindgut contraction is_a: GO:0045987 ! positive regulation of smooth muscle contraction is_a: GO:0060456 ! positive regulation of digestive system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0043133 ! positively regulates hindgut contraction relationship: RO:0002213 GO:0043133 ! positively regulates hindgut contraction [Term] id: GO:0060451 name: negative regulation of hindgut contraction namespace: biological_process def: "Any process that decreases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine." [GOC:dph, GOC:tb] is_a: GO:0043134 ! regulation of hindgut contraction is_a: GO:0045986 ! negative regulation of smooth muscle contraction is_a: GO:0060457 ! negative regulation of digestive system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0043133 ! negatively regulates hindgut contraction relationship: RO:0002212 GO:0043133 ! negatively regulates hindgut contraction [Term] id: GO:0060452 name: positive regulation of cardiac muscle contraction namespace: biological_process def: "Any process that increases the frequency, rate or extent of cardiac muscle contraction." [GOC:dph, GOC:tb] is_a: GO:0045823 ! positive regulation of heart contraction is_a: GO:0045989 ! positive regulation of striated muscle contraction is_a: GO:0055117 ! regulation of cardiac muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060048 ! positively regulates cardiac muscle contraction relationship: RO:0002213 GO:0060048 ! positively regulates cardiac muscle contraction [Term] id: GO:0060453 name: regulation of gastric acid secretion namespace: biological_process def: "Any process that modulates the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion." [GOC:dph, GOC:tb] is_a: GO:0044058 ! regulation of digestive system process is_a: GO:0051046 ! regulation of secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001696 ! regulates (processual) gastric acid secretion relationship: RO:0002211 GO:0001696 ! regulates (processual) gastric acid secretion [Term] id: GO:0060454 name: positive regulation of gastric acid secretion namespace: biological_process def: "Any process that increases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion." [GOC:dph, GOC:tb] is_a: GO:0051047 ! positive regulation of secretion is_a: GO:0060453 ! regulation of gastric acid secretion is_a: GO:0060456 ! positive regulation of digestive system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001696 ! positively regulates gastric acid secretion relationship: RO:0002213 GO:0001696 ! positively regulates gastric acid secretion [Term] id: GO:0060455 name: negative regulation of gastric acid secretion namespace: biological_process def: "Any process that decreases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion." [GOC:dph, GOC:tb] is_a: GO:0051048 ! negative regulation of secretion is_a: GO:0060453 ! regulation of gastric acid secretion is_a: GO:0060457 ! negative regulation of digestive system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001696 ! negatively regulates gastric acid secretion relationship: RO:0002212 GO:0001696 ! negatively regulates gastric acid secretion [Term] id: GO:0060456 name: positive regulation of digestive system process namespace: biological_process def: "Any process that increases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." [GOC:dph, GOC:tb] is_a: GO:0044058 ! regulation of digestive system process is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0022600 ! positively regulates digestive system process relationship: RO:0002213 GO:0022600 ! positively regulates digestive system process [Term] id: GO:0060457 name: negative regulation of digestive system process namespace: biological_process def: "Any process that decreases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." [GOC:dph, GOC:tb] is_a: GO:0044058 ! regulation of digestive system process is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0022600 ! negatively regulates digestive system process relationship: RO:0002212 GO:0022600 ! negatively regulates digestive system process [Term] id: GO:0060458 name: right lung development namespace: biological_process def: "The biological process whose specific outcome is the progression of a right lung from an initial condition to its mature state. This process begins with the formation of the right lung and ends with the mature structure. The right lung is the lung which is on the right side of the anterior posterior axis looking from a dorsal to ventral aspect." [GOC:dph, GOC:mtg_lung] synonym: "right pulmonary development" EXACT [GOC:dph, GOC:mtg_lung] is_a: GO:0030324 ! lung development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002167 ! results in development of right lung relationship: RO:0002296 UBERON:0002167 ! results in development of right lung [Term] id: GO:0060459 name: left lung development namespace: biological_process def: "The biological process whose specific outcome is the progression of a left lung from an initial condition to its mature state. This process begins with the formation of the left lung and ends with the mature structure. The left lung is the lung which is on the left side of the anterior posterior axis looking from a dorsal to ventral aspect." [GOC:dph, GOC:mtg_lung] synonym: "left pulmonary development" EXACT [GOC:dph] is_a: GO:0030324 ! lung development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002168 ! results in development of left lung relationship: RO:0002296 UBERON:0002168 ! results in development of left lung [Term] id: GO:0060460 name: left lung morphogenesis namespace: biological_process def: "The process in which anatomical structures of the left lung are generated and organized." [GOC:dph] is_a: GO:0060425 ! lung morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002168 ! results in morphogenesis of left lung relationship: BFO:0000050 GO:0060459 ! part of left lung development relationship: RO:0002298 UBERON:0002168 ! results in morphogenesis of left lung [Term] id: GO:0060461 name: right lung morphogenesis namespace: biological_process def: "The process in which anatomical structures of the right lung are generated and organized." [GOC:dph, GOC:mtg_lung] is_a: GO:0060425 ! lung morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002167 ! results in morphogenesis of right lung relationship: BFO:0000050 GO:0060458 ! part of right lung development relationship: RO:0002298 UBERON:0002167 ! results in morphogenesis of right lung [Term] id: GO:0060462 name: lung lobe development namespace: biological_process def: "The biological process whose specific outcome is the progression of a lung lobe from an initial condition to its mature state. This process begins with the formation of a lung lobe by branching morphogenesis and ends with the mature structure. A lung lobe is one of the rounded projections that compose the lung." [GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000101 ! results in development of lobe of lung relationship: BFO:0000050 GO:0030324 ! part of lung development relationship: RO:0002296 UBERON:0000101 ! results in development of lobe of lung [Term] id: GO:0060463 name: lung lobe morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a lung lobe are generated and organized. A lung lobe is a projection that extends from the lung." [GOC:dph] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000101 ! results in morphogenesis of lobe of lung relationship: BFO:0000050 GO:0060425 ! part of lung morphogenesis relationship: BFO:0000050 GO:0060462 ! part of lung lobe development relationship: RO:0002298 UBERON:0000101 ! results in morphogenesis of lobe of lung [Term] id: GO:0060464 name: lung lobe formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a lung lobe from unspecified parts. This process begins with the specific processes that contribute to the appearance of the lobe and ends when the structural rudiment is recognizable. A lung lobe is a projection that extends from the lung." [GOC:dph] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0000101 ! results in formation of anatomical entity lobe of lung relationship: BFO:0000050 GO:0060463 ! part of lung lobe morphogenesis relationship: RO:0002297 UBERON:0000101 ! results in formation of anatomical entity lobe of lung [Term] id: GO:0060465 name: pharynx development namespace: biological_process def: "The biological process whose specific outcome is the progression of a pharynx from an initial condition to its mature state. The pharynx is the part of the digestive system immediately posterior to the mouth." [GOC:dph, GOC:rk] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0006562 ! results in development of pharynx relationship: BFO:0000050 GO:0048565 ! part of digestive tract development relationship: RO:0002296 UBERON:0006562 ! results in development of pharynx [Term] id: GO:0060467 name: negative regulation of fertilization namespace: biological_process def: "Any process that decreases the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy)." [GOC:dph] is_a: GO:0080154 ! regulation of fertilization is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0009566 ! negatively regulates fertilization relationship: RO:0002212 GO:0009566 ! negatively regulates fertilization [Term] id: GO:0060468 name: prevention of polyspermy namespace: biological_process def: "The negative regulation of fertilization process that takes place as part of egg activation, ensuring that only a single sperm fertilizes the egg." [GOC:dph] synonym: "negative regulation of fertilization involved in egg activation" EXACT [GOC:dph] synonym: "polyspermy block" EXACT [GOC:dph] is_a: GO:0022414 ! reproductive process is_a: GO:0060467 ! negative regulation of fertilization intersection_of: GO:0060467 ! negative regulation of fertilization intersection_of: BFO:0000050 GO:0007343 ! part of egg activation relationship: BFO:0000050 GO:0007343 ! part of egg activation [Term] id: GO:0060474 name: positive regulation of flagellated sperm motility involved in capacitation namespace: biological_process def: "The process in which the controlled movement of a flagellated sperm cell is initiated as part of the process required for flagellated sperm to reach fertilization competence." [GOC:cilia, GOC:dph, GOC:krc] is_a: GO:0022414 ! reproductive process is_a: GO:1902093 ! positive regulation of flagellated sperm motility intersection_of: GO:1902093 ! positive regulation of flagellated sperm motility intersection_of: BFO:0000050 GO:0048240 ! part of sperm capacitation relationship: BFO:0000050 GO:0048240 ! part of sperm capacitation [Term] id: GO:0060479 name: lung cell differentiation namespace: biological_process def: "The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GOC:dph, GOC:mtg_lung] synonym: "pulmonary cell differentiation" EXACT [GOC:dph] is_a: GO:0030154 ! cell differentiation relationship: BFO:0000050 GO:0030324 ! part of lung development [Term] id: GO:0060485 name: mesenchyme development namespace: biological_process def: "The process whose specific outcome is the progression of a mesenchymal tissue over time, from its formation to the mature structure. A mesenchymal tissue is made up of loosely packed stellate cells." [GOC:dph] synonym: "mesenchymal development" EXACT [GOC:dph] is_a: GO:0009888 ! tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003104 ! results in development of mesenchyme relationship: BFO:0000050 GO:0048513 ! part of animal organ development relationship: RO:0002296 UBERON:0003104 ! results in development of mesenchyme [Term] id: GO:0060487 name: lung epithelial cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell that contributes to the epithelium of the lung." [GOC:dph] is_a: GO:0030855 ! epithelial cell differentiation is_a: GO:0060479 ! lung cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000082 ! results in acquisition of features of epithelial cell of lung relationship: BFO:0000050 GO:0060428 ! part of lung epithelium development relationship: RO:0002315 CL:0000082 ! results in acquisition of features of epithelial cell of lung [Term] id: GO:0060491 name: regulation of cell projection assembly namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of cell projection assembly." [GOC:dph, GOC:tb] is_a: GO:0031344 ! regulation of cell projection organization is_a: GO:0044087 ! regulation of cellular component biogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030031 ! regulates (processual) cell projection assembly relationship: RO:0002211 GO:0030031 ! regulates (processual) cell projection assembly [Term] id: GO:0060495 name: cell-cell signaling involved in lung development namespace: biological_process def: "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the lung, from its initial state to the mature structure." [GOC:dph, GOC:mtg_lung] synonym: "cell-cell signalling involved in lung development" EXACT [GOC:mah] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: BFO:0000050 GO:0030324 ! part of lung development relationship: BFO:0000050 GO:0030324 ! part of lung development [Term] id: GO:0060496 name: mesenchymal-epithelial cell signaling involved in lung development namespace: biological_process def: "Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell and contributes to the development of the lung." [GOC:dph, GOC:mtg_lung] synonym: "mesenchymal-epithelial cell signalling involved in lung development" EXACT [GOC:mah] is_a: GO:0060495 ! cell-cell signaling involved in lung development is_a: GO:0060638 ! mesenchymal-epithelial cell signaling intersection_of: GO:0060638 ! mesenchymal-epithelial cell signaling intersection_of: BFO:0000050 GO:0030324 ! part of lung development [Term] id: GO:0060497 name: mesenchymal-endodermal cell signaling namespace: biological_process def: "Any process that mediates the transfer of information between a mesenchymal cell and an endodermal cell." [GOC:dph] synonym: "mesenchymal-endodermal cell signalling" EXACT [GOC:mah] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: RO:0002231 CL:0008019 ! has start location mesenchymal cell intersection_of: RO:0002232 CL:0000223 ! has end location endodermal cell relationship: RO:0002231 CL:0008019 ! has start location mesenchymal cell relationship: RO:0002232 CL:0000223 ! has end location endodermal cell [Term] id: GO:0060501 name: positive regulation of epithelial cell proliferation involved in lung morphogenesis namespace: biological_process def: "Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung attaining its shape." [GOC:dph] is_a: GO:0050679 ! positive regulation of epithelial cell proliferation is_a: GO:2000794 ! regulation of epithelial cell proliferation involved in lung morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060502 ! positively regulates epithelial cell proliferation involved in lung morphogenesis relationship: RO:0002213 GO:0060502 ! positively regulates epithelial cell proliferation involved in lung morphogenesis [Term] id: GO:0060502 name: epithelial cell proliferation involved in lung morphogenesis namespace: biological_process def: "The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the lung." [GOC:dph] is_a: GO:0050673 ! epithelial cell proliferation intersection_of: GO:0050673 ! epithelial cell proliferation intersection_of: BFO:0000050 GO:0060425 ! part of lung morphogenesis relationship: BFO:0000050 GO:0060425 ! part of lung morphogenesis relationship: BFO:0000050 GO:0060428 ! part of lung epithelium development [Term] id: GO:0060536 name: cartilage morphogenesis namespace: biological_process def: "The process in which the anatomical structures of cartilage are generated and organized." [GOC:dph] is_a: GO:0009887 ! animal organ morphogenesis is_a: GO:0048729 ! tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0007844 ! results in morphogenesis of cartilage element relationship: BFO:0000050 GO:0051216 ! part of cartilage development relationship: RO:0002298 UBERON:0007844 ! results in morphogenesis of cartilage element creation_date: 2009-04-10T09:13:27Z [Term] id: GO:0060537 name: muscle tissue development namespace: biological_process def: "The progression of muscle tissue over time, from its initial formation to its mature state. Muscle tissue is a contractile tissue made up of actin and myosin fibers." [GOC:dph] is_a: GO:0009888 ! tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002385 ! results in development of muscle tissue relationship: RO:0002296 UBERON:0002385 ! results in development of muscle tissue creation_date: 2009-04-10T08:05:37Z [Term] id: GO:0060538 name: skeletal muscle organ development namespace: biological_process def: "The progression of a skeletal muscle organ over time from its initial formation to its mature state. A skeletal muscle organ includes the skeletal muscle tissue and its associated connective tissue." [GOC:dph] is_a: GO:0007517 ! muscle organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0014892 ! results in development of skeletal muscle organ, vertebrate relationship: RO:0002296 UBERON:0014892 ! results in development of skeletal muscle organ, vertebrate creation_date: 2009-04-10T08:25:12Z [Term] id: GO:0060539 name: diaphragm development namespace: biological_process def: "The progression of the diaphragm over time from its initial formation to the mature structure. The diaphragm is a skeletal muscle that is responsible for contraction and expansion of the lungs." [GOC:dph] is_a: GO:0060538 ! skeletal muscle organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001103 ! results in development of diaphragm relationship: BFO:0000050 GO:0060541 ! part of respiratory system development relationship: RO:0002296 UBERON:0001103 ! results in development of diaphragm creation_date: 2009-04-10T08:44:56Z [Term] id: GO:0060540 name: diaphragm morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the diaphragm are generated and organized." [GOC:dph] is_a: GO:0048644 ! muscle organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001103 ! results in morphogenesis of diaphragm relationship: BFO:0000050 GO:0060539 ! part of diaphragm development relationship: RO:0002298 UBERON:0001103 ! results in morphogenesis of diaphragm creation_date: 2009-04-10T08:47:51Z [Term] id: GO:0060541 name: respiratory system development namespace: biological_process def: "The progression of the respiratory system over time from its formation to its mature structure. The respiratory system carries out respiratory gaseous exchange." [GOC:dph] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001004 ! results in development of respiratory system relationship: RO:0002296 UBERON:0001004 ! results in development of respiratory system creation_date: 2009-04-10T08:55:42Z [Term] id: GO:0060560 name: developmental growth involved in morphogenesis namespace: biological_process def: "The increase in size or mass of an anatomical structure that contributes to the structure attaining its shape." [GOC:dph] synonym: "differential growth" EXACT [GOC:dph] is_a: GO:0048589 ! developmental growth intersection_of: GO:0048589 ! developmental growth intersection_of: BFO:0000050 GO:0009653 ! part of anatomical structure morphogenesis relationship: BFO:0000050 GO:0009653 ! part of anatomical structure morphogenesis creation_date: 2009-04-28T08:42:53Z [Term] id: GO:0060561 name: apoptotic process involved in morphogenesis namespace: biological_process def: "Any apoptotic process that contributes to the shaping of an anatomical structure." [GOC:dph, GOC:mtg_apoptosis] is_a: GO:1902742 ! apoptotic process involved in development intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000050 GO:0009653 ! part of anatomical structure morphogenesis relationship: BFO:0000050 GO:0009653 ! part of anatomical structure morphogenesis creation_date: 2009-04-28T09:17:27Z [Term] id: GO:0060562 name: epithelial tube morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a tube are generated and organized from an epithelium. Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system." [GOC:dph] is_a: GO:0002009 ! morphogenesis of an epithelium is_a: GO:0035239 ! tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003914 ! results in morphogenesis of epithelial tube relationship: RO:0002298 UBERON:0003914 ! results in morphogenesis of epithelial tube creation_date: 2009-04-28T09:33:36Z [Term] id: GO:0060563 name: neuroepithelial cell differentiation namespace: biological_process def: "The process in which epiblast cells acquire specialized features of neuroepithelial cells." [GOC:dph, GOC:tb] is_a: GO:0002065 ! columnar/cuboidal epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000710 ! results in acquisition of features of neurecto-epithelial cell relationship: RO:0002315 CL:0000710 ! results in acquisition of features of neurecto-epithelial cell creation_date: 2009-04-29T01:50:05Z [Term] id: GO:0060571 name: morphogenesis of an epithelial fold namespace: biological_process def: "The morphogenetic process in which an epithelial sheet bends along a linear axis." [GOC:dph] synonym: "epithelial folding" EXACT [GOC:dph] is_a: GO:0002009 ! morphogenesis of an epithelium intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0005157 ! results in morphogenesis of epithelial fold relationship: RO:0002298 UBERON:0005157 ! results in morphogenesis of epithelial fold creation_date: 2009-04-30T09:27:17Z [Term] id: GO:0060572 name: morphogenesis of an epithelial bud namespace: biological_process def: "The morphogenetic process in which a bud forms from an epithelial sheet. A bud is a protrusion that forms form the sheet by localized folding." [GOC:dph] is_a: GO:0060571 ! morphogenesis of an epithelial fold intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0005153 ! results in morphogenesis of epithelial bud relationship: RO:0002298 UBERON:0005153 ! results in morphogenesis of epithelial bud creation_date: 2009-04-30T09:38:35Z [Term] id: GO:0060574 name: intestinal epithelial cell maturation namespace: biological_process def: "The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell of the intestine to attain its fully functional state. A columnar/cuboidal epithelial cell of the intestine mature as they migrate from the intestinal crypt to the villus." [GOC:dph, PMID:18824147] is_a: GO:0002069 ! columnar/cuboidal epithelial cell maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 CL:0002563 ! results in maturation of intestinal epithelial cell relationship: BFO:0000050 GO:0060576 ! part of intestinal epithelial cell development relationship: RO:0002299 CL:0002563 ! results in maturation of intestinal epithelial cell creation_date: 2009-05-06T08:10:41Z [Term] id: GO:0060575 name: intestinal epithelial cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell of the intestine." [GOC:dph] is_a: GO:0002065 ! columnar/cuboidal epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0002563 ! results in acquisition of features of intestinal epithelial cell relationship: BFO:0000050 GO:0048565 ! part of digestive tract development relationship: RO:0002315 CL:0002563 ! results in acquisition of features of intestinal epithelial cell creation_date: 2009-05-06T08:17:56Z [Term] id: GO:0060576 name: intestinal epithelial cell development namespace: biological_process def: "The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell of the intestine over time, from its formation to the mature structure." [GOC:dph] is_a: GO:0002066 ! columnar/cuboidal epithelial cell development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 CL:0002563 ! results in development of intestinal epithelial cell relationship: BFO:0000050 GO:0060575 ! part of intestinal epithelial cell differentiation relationship: RO:0002296 CL:0002563 ! results in development of intestinal epithelial cell creation_date: 2009-05-06T08:20:24Z [Term] id: GO:0060577 name: pulmonary vein morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the pulmonary venous blood vessels are generated and organized. Pulmonary veins are blood vessels that transport blood from the lungs to the heart." [GOC:dph] is_a: GO:0048845 ! venous blood vessel morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002016 ! results in morphogenesis of pulmonary vein relationship: RO:0002298 UBERON:0002016 ! results in morphogenesis of pulmonary vein creation_date: 2009-05-06T08:44:04Z [Term] id: GO:0060578 name: superior vena cava morphogenesis namespace: biological_process def: "The process in which the anatomical structure of superior vena cava generated and organized. The superior vena cava is a blood vessel that transports blood from the upper body to the heart." [GOC:dph] is_a: GO:0048845 ! venous blood vessel morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001585 ! results in morphogenesis of anterior vena cava relationship: RO:0002298 UBERON:0001585 ! results in morphogenesis of anterior vena cava creation_date: 2009-05-06T08:47:21Z [Term] id: GO:0060581 name: cell fate commitment involved in pattern specification namespace: biological_process def: "The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells within a field of cells that will exhibit a certain pattern of differentiation. Positional information is established through protein signals that emanate from a localized source within a developmental field resulting in specification of a cell type. Those signals are then interpreted in a cell-autonomous manner resulting in the determination of the cell type." [GOC:dph] is_a: GO:0045165 ! cell fate commitment intersection_of: GO:0045165 ! cell fate commitment intersection_of: BFO:0000050 GO:0007389 ! part of pattern specification process relationship: BFO:0000050 GO:0007389 ! part of pattern specification process creation_date: 2009-05-07T12:40:55Z [Term] id: GO:0060591 name: chondroblast differentiation namespace: biological_process def: "The process in which a mesenchymal cell, acquires specialized structural and/or functional features of a chondroblast. Differentiation includes the processes involved in commitment of a cell to a chondroblast fate. A chondroblast is a precursor cell to chondrocytes." [GOC:dph] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000058 ! results in acquisition of features of chondroblast relationship: BFO:0000050 GO:0051216 ! part of cartilage development relationship: RO:0002315 CL:0000058 ! results in acquisition of features of chondroblast creation_date: 2009-05-11T07:47:36Z [Term] id: GO:0060612 name: adipose tissue development namespace: biological_process def: "The process whose specific outcome is the progression of adipose tissue over time, from its formation to the mature structure. Adipose tissue is specialized tissue that is used to store fat." [GOC:dph] is_a: GO:0061448 ! connective tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001013 ! results in development of adipose tissue relationship: BFO:0000050 GO:0048513 ! part of animal organ development relationship: RO:0002296 UBERON:0001013 ! results in development of adipose tissue creation_date: 2009-05-15T12:36:28Z [Term] id: GO:0060623 name: regulation of chromosome condensation namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of chromosome condensation, the progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells." [GOC:dph, GOC:tb] is_a: GO:0033044 ! regulation of chromosome organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030261 ! regulates (processual) chromosome condensation relationship: RO:0002211 GO:0030261 ! regulates (processual) chromosome condensation creation_date: 2009-05-18T02:12:13Z [Term] id: GO:0060627 name: regulation of vesicle-mediated transport namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell." [GOC:dph, GOC:tb] is_a: GO:0050794 ! regulation of cellular process is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0016192 ! regulates (processual) vesicle-mediated transport relationship: RO:0002211 GO:0016192 ! regulates (processual) vesicle-mediated transport creation_date: 2009-05-18T02:29:43Z [Term] id: GO:0060632 name: regulation of microtubule-based movement namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of microtubule-based movement, the movement of organelles, other microtubules and other particles along microtubules, mediated by motor proteins." [GOC:dph, GOC:tb] is_a: GO:0032886 ! regulation of microtubule-based process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007018 ! regulates (processual) microtubule-based movement relationship: RO:0002211 GO:0007018 ! regulates (processual) microtubule-based movement creation_date: 2009-05-18T03:07:02Z [Term] id: GO:0060638 name: mesenchymal-epithelial cell signaling namespace: biological_process def: "Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell where it is received and interpreted." [GOC:dph] synonym: "mesenchymal-epithelial cell signalling" EXACT [GOC:mah] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: RO:0002231 CL:0008019 ! has start location mesenchymal cell intersection_of: RO:0002232 CL:0000066 ! has end location epithelial cell relationship: RO:0002231 CL:0008019 ! has start location mesenchymal cell relationship: RO:0002232 CL:0000066 ! has end location epithelial cell creation_date: 2009-05-19T03:59:05Z [Term] id: GO:0060669 name: embryonic placenta morphogenesis namespace: biological_process def: "The process in which the embryonic placenta is generated and organized." [GOC:dph] is_a: GO:0048598 ! embryonic morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0007106 ! results in morphogenesis of chorionic villus relationship: BFO:0000050 GO:0001892 ! part of embryonic placenta development relationship: RO:0002298 UBERON:0007106 ! results in morphogenesis of chorionic villus creation_date: 2009-06-02T09:33:37Z [Term] id: GO:0060670 name: branching involved in labyrinthine layer morphogenesis namespace: biological_process def: "The process in which the branches of the fetal placental villi are generated and organized. The villous part of the placenta is called the labyrinth layer." [GOC:dph, PMID:16916377] is_a: GO:0048598 ! embryonic morphogenesis is_a: GO:0061138 ! morphogenesis of a branching epithelium intersection_of: GO:0061138 ! morphogenesis of a branching epithelium intersection_of: BFO:0000050 GO:0060713 ! part of labyrinthine layer morphogenesis relationship: BFO:0000050 GO:0060713 ! part of labyrinthine layer morphogenesis creation_date: 2009-06-02T10:40:40Z [Term] id: GO:0060671 name: epithelial cell differentiation involved in embryonic placenta development namespace: biological_process def: "The process in which a trophoblast cell acquires specialized features of an epithelial cell of the placental labyrinthine layer." [GOC:dph, PMID:16916377] is_a: GO:0030855 ! epithelial cell differentiation is_a: GO:0060706 ! cell differentiation involved in embryonic placenta development intersection_of: GO:0030855 ! epithelial cell differentiation intersection_of: BFO:0000050 GO:0001892 ! part of embryonic placenta development relationship: BFO:0000050 GO:0060711 ! part of labyrinthine layer development creation_date: 2009-06-02T11:40:52Z [Term] id: GO:0060673 name: cell-cell signaling involved in placenta development namespace: biological_process def: "Any process that mediates the transfer of information from one cell to another." [GOC:dph, PMID:16916377] synonym: "cell-cell signalling involved in placenta development" EXACT [GOC:mah] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: BFO:0000050 GO:0001890 ! part of placenta development relationship: BFO:0000050 GO:0001892 ! part of embryonic placenta development creation_date: 2009-06-02T12:58:03Z [Term] id: GO:0060674 name: placenta blood vessel development namespace: biological_process def: "The process whose specific outcome is the progression of a blood vessel of the placenta over time, from its formation to the mature structure." [GOC:dph, PMID:16916377] is_a: GO:0001568 ! blood vessel development relationship: BFO:0000050 GO:0001890 ! part of placenta development creation_date: 2009-06-02T01:09:43Z [Term] id: GO:0060675 name: ureteric bud morphogenesis namespace: biological_process def: "The process in which the ureteric bud is generated and organized." [GOC:dph, GOC:mtg_kidney_jan10] is_a: GO:0072171 ! mesonephric tubule morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000084 ! results in morphogenesis of ureteric bud relationship: BFO:0000050 GO:0001657 ! part of ureteric bud development relationship: RO:0002298 UBERON:0000084 ! results in morphogenesis of ureteric bud creation_date: 2009-06-02T01:31:41Z [Term] id: GO:0060676 name: ureteric bud formation namespace: biological_process def: "The developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct. This process begins when the bud protrudes from the duct and ends when it is a recognizable bud." [GOC:dph, PMID:16916378] is_a: GO:0072172 ! mesonephric tubule formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0000084 ! results in formation of anatomical entity ureteric bud relationship: BFO:0000050 GO:0060675 ! part of ureteric bud morphogenesis relationship: RO:0002297 UBERON:0000084 ! results in formation of anatomical entity ureteric bud creation_date: 2009-06-02T01:47:23Z [Term] id: GO:0060684 name: epithelial-mesenchymal cell signaling namespace: biological_process def: "Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell where it is interpreted." [GOC:dph] synonym: "epithelial-mesenchymal cell signalling" EXACT [GOC:mah] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: RO:0002231 CL:0000066 ! has start location epithelial cell intersection_of: RO:0002232 CL:0008019 ! has end location mesenchymal cell relationship: RO:0002231 CL:0000066 ! has start location epithelial cell relationship: RO:0002232 CL:0008019 ! has end location mesenchymal cell creation_date: 2009-06-03T06:36:46Z [Term] id: GO:0060688 name: regulation of morphogenesis of a branching structure namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of branching morphogenesis, the process in which the anatomical structures of branches are generated and organized." [GOC:dph] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001763 ! regulates (processual) morphogenesis of a branching structure relationship: RO:0002211 GO:0001763 ! regulates (processual) morphogenesis of a branching structure creation_date: 2009-06-05T12:41:44Z [Term] id: GO:0060706 name: cell differentiation involved in embryonic placenta development namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of the embryonic placenta." [GOC:dph] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: BFO:0000050 GO:0001892 ! part of embryonic placenta development relationship: BFO:0000050 GO:0001892 ! part of embryonic placenta development creation_date: 2009-06-09T10:26:42Z [Term] id: GO:0060711 name: labyrinthine layer development namespace: biological_process def: "The process in which the labyrinthine layer of the placenta progresses, from its formation to its mature state." [GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003946 ! results in development of placenta labyrinth relationship: BFO:0000050 GO:0001892 ! part of embryonic placenta development relationship: RO:0002296 UBERON:0003946 ! results in development of placenta labyrinth creation_date: 2009-06-09T03:27:43Z [Term] id: GO:0060713 name: labyrinthine layer morphogenesis namespace: biological_process def: "The process in which the labyrinthine layer of the placenta is generated and organized." [GOC:dph] is_a: GO:0048598 ! embryonic morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003946 ! results in morphogenesis of placenta labyrinth relationship: BFO:0000050 GO:0060669 ! part of embryonic placenta morphogenesis relationship: BFO:0000050 GO:0060711 ! part of labyrinthine layer development relationship: RO:0002298 UBERON:0003946 ! results in morphogenesis of placenta labyrinth creation_date: 2009-06-10T08:10:19Z [Term] id: GO:0060714 name: labyrinthine layer formation namespace: biological_process def: "The developmental process pertaining to the initial formation of the labyrinthine layer of the placenta." [GOC:dph] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0003946 ! results in formation of anatomical entity placenta labyrinth relationship: BFO:0000050 GO:0060713 ! part of labyrinthine layer morphogenesis relationship: RO:0002297 UBERON:0003946 ! results in formation of anatomical entity placenta labyrinth creation_date: 2009-06-10T08:13:14Z [Term] id: GO:0060716 name: labyrinthine layer blood vessel development namespace: biological_process def: "The process whose specific outcome is the progression of a blood vessel of the labyrinthine layer of the placenta over time, from its formation to the mature structure. The embryonic vessels grow through the layer to come in close contact with the maternal blood supply." [GOC:dph] is_a: GO:0048568 ! embryonic organ development is_a: GO:0060674 ! placenta blood vessel development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004183 ! results in development of placental labyrinth blood vessel relationship: BFO:0000050 GO:0060711 ! part of labyrinthine layer development relationship: RO:0002296 UBERON:0004183 ! results in development of placental labyrinth blood vessel creation_date: 2009-06-11T09:04:38Z [Term] id: GO:0060717 name: chorion development namespace: biological_process def: "The biological process whose specific outcome is the progression of a chorion from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The chorion is an extraembryonic membrane." [GOC:dph] is_a: GO:1903867 ! extraembryonic membrane development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003124 ! results in development of chorion membrane relationship: RO:0002296 UBERON:0003124 ! results in development of chorion membrane creation_date: 2009-06-11T02:37:50Z [Term] id: GO:0060718 name: chorionic trophoblast cell differentiation namespace: biological_process def: "The process in which relatively unspecialized cells of the ectoplacental cone acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer." [CL:0011101, GOC:dph, PMID:16983341] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0011101 ! results in acquisition of features of chorionic trophoblast cell relationship: BFO:0000050 GO:0060717 ! part of chorion development relationship: RO:0002315 CL:0011101 ! results in acquisition of features of chorionic trophoblast cell creation_date: 2009-06-11T02:48:27Z [Term] id: GO:0060719 name: chorionic trophoblast cell development namespace: biological_process def: "The process whose specific outcome is the progression of the chorionic trophoblast over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." [CL:0011101, GOC:16983341, GOC:dph] is_a: GO:0048468 ! cell development intersection_of: GO:0048468 ! cell development intersection_of: RO:0002296 CL:0011101 ! results in development of chorionic trophoblast cell relationship: BFO:0000050 GO:0060718 ! part of chorionic trophoblast cell differentiation relationship: RO:0002296 CL:0011101 ! results in development of chorionic trophoblast cell creation_date: 2009-06-11T02:58:45Z [Term] id: GO:0060722 name: cell proliferation involved in embryonic placenta development namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of the population in the embryonic placenta." [GOC:dph] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: BFO:0000050 GO:0001892 ! part of embryonic placenta development relationship: BFO:0000050 GO:0001892 ! part of embryonic placenta development creation_date: 2009-06-12T12:46:04Z [Term] id: GO:0060723 name: regulation of cell proliferation involved in embryonic placenta development namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of cell proliferation involved in embryonic placenta development." [GOC:dph] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060722 ! regulates (processual) cell proliferation involved in embryonic placenta development relationship: RO:0002211 GO:0060722 ! regulates (processual) cell proliferation involved in embryonic placenta development creation_date: 2009-06-12T12:50:23Z [Term] id: GO:0060788 name: ectodermal placode formation namespace: biological_process def: "The developmental process in which an ectodermal placode forms. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0005085 ! results in formation of anatomical entity ectodermal placode relationship: BFO:0000050 GO:0071697 ! part of ectodermal placode morphogenesis relationship: RO:0002297 UBERON:0005085 ! results in formation of anatomical entity ectodermal placode creation_date: 2009-08-04T12:15:57Z [Term] id: GO:0060795 name: cell fate commitment involved in formation of primary germ layer namespace: biological_process def: "The commitment of cells to specific cell fates of the endoderm, ectoderm, or mesoderm as a part of gastrulation." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0045165 ! cell fate commitment intersection_of: GO:0045165 ! cell fate commitment intersection_of: BFO:0000050 GO:0001704 ! part of formation of primary germ layer relationship: BFO:0000050 GO:0001704 ! part of formation of primary germ layer creation_date: 2009-08-04T03:11:22Z [Term] id: GO:0060800 name: regulation of cell differentiation involved in embryonic placenta development namespace: biological_process def: "Any process that modulates the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0045595 ! regulation of cell differentiation is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060706 ! regulates (processual) cell differentiation involved in embryonic placenta development relationship: RO:0002211 GO:0060706 ! regulates (processual) cell differentiation involved in embryonic placenta development creation_date: 2009-08-06T01:20:25Z [Term] id: GO:0060806 name: negative regulation of cell differentiation involved in embryonic placenta development namespace: biological_process def: "Any process that decreases the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0060800 ! regulation of cell differentiation involved in embryonic placenta development is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060706 ! negatively regulates cell differentiation involved in embryonic placenta development relationship: RO:0002212 GO:0060706 ! negatively regulates cell differentiation involved in embryonic placenta development creation_date: 2009-08-06T02:02:18Z [Term] id: GO:0060815 name: regulation of translation involved in anterior/posterior axis specification namespace: biological_process def: "Any process that modulates the frequency, rate or extent of translation of mRNAs that contribute to the specification of the anterior/posterior axis." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0006417 ! regulation of translation intersection_of: GO:0006417 ! regulation of translation intersection_of: BFO:0000050 GO:0009948 ! part of anterior/posterior axis specification relationship: BFO:0000050 GO:0009948 ! part of anterior/posterior axis specification creation_date: 2009-08-07T10:02:31Z [Term] id: GO:0060837 name: blood vessel endothelial cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell, a thin flattened cell that lines the inside surfaces of blood vessels." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0045446 ! endothelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000071 ! results in acquisition of features of blood vessel endothelial cell relationship: BFO:0000050 GO:0001568 ! part of blood vessel development relationship: RO:0002315 CL:0000071 ! results in acquisition of features of blood vessel endothelial cell creation_date: 2009-08-11T03:47:36Z [Term] id: GO:0060840 name: artery development namespace: biological_process def: "The progression of the artery over time, from its initial formation to the mature structure. An artery is a blood vessel that carries blood away from the heart to a capillary bed." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0001568 ! blood vessel development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001637 ! results in development of artery relationship: RO:0002296 UBERON:0001637 ! results in development of artery creation_date: 2009-08-12T10:10:51Z [Term] id: GO:0060841 name: venous blood vessel development namespace: biological_process def: "The progression of the venous blood vessel over time from its initial formation to the mature structure. Venous blood vessels carry blood back to the heart after the capillary bed." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0001568 ! blood vessel development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001638 ! results in development of vein relationship: RO:0002296 UBERON:0001638 ! results in development of vein creation_date: 2009-08-12T10:14:07Z [Term] id: GO:0060842 name: arterial endothelial cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized endothelial cell acquires specialized features of an arterial endothelial cell, a thin flattened cell that lines the inside surfaces of arteries." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0060837 ! blood vessel endothelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:1000413 ! results in acquisition of features of endothelial cell of artery relationship: RO:0002315 CL:1000413 ! results in acquisition of features of endothelial cell of artery creation_date: 2009-08-12T10:41:34Z [Term] id: GO:0060843 name: venous endothelial cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized endothelial cell acquires specialized features of a venous endothelial cell, a thin flattened cell that lines the inside surfaces of veins." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0060837 ! blood vessel endothelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0002543 ! results in acquisition of features of vein endothelial cell relationship: RO:0002315 CL:0002543 ! results in acquisition of features of vein endothelial cell creation_date: 2009-08-12T10:43:40Z [Term] id: GO:0060896 name: neural plate pattern specification namespace: biological_process def: "The developmental process that results in the creation of defined areas or spaces within the neural plate to which cells respond and eventually are instructed to differentiate." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0007389 ! pattern specification process creation_date: 2009-08-13T02:06:27Z [Term] id: GO:0060897 name: neural plate regionalization namespace: biological_process def: "The pattern specification process that results in the subdivision of an axis or axes of the neural plate in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0003002 ! regionalization is_a: GO:0060896 ! neural plate pattern specification creation_date: 2009-08-13T02:09:04Z [Term] id: GO:0060900 name: embryonic camera-type eye formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a camera-type eye from unspecified neurectoderm. This process begins with the differentiation of cells that form the optic field and ends when the optic cup has attained its shape." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis relationship: BFO:0000050 GO:0048596 ! part of embryonic camera-type eye morphogenesis creation_date: 2009-08-13T02:26:54Z [Term] id: GO:0060914 name: heart formation namespace: biological_process def: "The developmental process pertaining to the initial formation of the heart from unspecified parts. This process begins with the specific processes that contribute to the appearance of the heart field and the arrival of cardiac neural crest to the heart region. The process ends when the structural rudiment is recognizable." [GOC:mtg_heart] is_a: GO:0048645 ! animal organ formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0000948 ! results in formation of anatomical entity heart relationship: BFO:0000050 GO:0003007 ! part of heart morphogenesis relationship: RO:0002297 UBERON:0000948 ! results in formation of anatomical entity heart creation_date: 2009-09-17T09:02:13Z [Term] id: GO:0060915 name: mesenchymal cell differentiation involved in lung development namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the lung. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types." [GOC:dph] is_a: GO:0048762 ! mesenchymal cell differentiation intersection_of: GO:0048762 ! mesenchymal cell differentiation intersection_of: BFO:0000050 GO:0030324 ! part of lung development relationship: BFO:0000050 GO:0030324 ! part of lung development creation_date: 2009-09-18T11:45:33Z [Term] id: GO:0060916 name: mesenchymal cell proliferation involved in lung development namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population that contributes to the progression of the lung over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." [GOC:dph] is_a: GO:0010463 ! mesenchymal cell proliferation intersection_of: GO:0010463 ! mesenchymal cell proliferation intersection_of: BFO:0000050 GO:0030324 ! part of lung development relationship: BFO:0000050 GO:0030324 ! part of lung development creation_date: 2009-09-18T11:50:17Z [Term] id: GO:0060920 name: cardiac pacemaker cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a pacemaker cell. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions." [GOC:mtg_cardiac_conduct_nov11, GOC:mtg_heart] is_a: GO:0055007 ! cardiac muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0002072 ! results in acquisition of features of nodal myocyte relationship: RO:0002315 CL:0002072 ! results in acquisition of features of nodal myocyte creation_date: 2009-09-29T11:01:31Z [Term] id: GO:0060921 name: sinoatrial node cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a sinoatrial (SA) node cell. SA node cells are pacemaker cells that are found in the sinoatrial node." [GOC:mtg_heart] synonym: "SA node cell differentiation" EXACT [GOC:mtg_heart] synonym: "SAN cell differentiation" EXACT [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] is_a: GO:0060920 ! cardiac pacemaker cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:1000409 ! results in acquisition of features of myocyte of sinoatrial node relationship: BFO:0000050 GO:0003163 ! part of sinoatrial node development relationship: RO:0002315 CL:1000409 ! results in acquisition of features of myocyte of sinoatrial node creation_date: 2009-09-29T11:03:30Z [Term] id: GO:0060922 name: atrioventricular node cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of an atrioventricular (AV) node cell. AV node cells are pacemaker cells that are found in the atrioventricular node." [GOC:mtg_heart] is_a: GO:0003292 ! cardiac septum cell differentiation is_a: GO:0060920 ! cardiac pacemaker cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:1000410 ! results in acquisition of features of myocyte of atrioventricular node relationship: BFO:0000050 GO:0003162 ! part of atrioventricular node development relationship: RO:0002315 CL:1000410 ! results in acquisition of features of myocyte of atrioventricular node creation_date: 2009-09-29T11:07:06Z [Term] id: GO:0060926 name: cardiac pacemaker cell development namespace: biological_process def: "The process whose specific outcome is the progression of a pacemaker cell over time, from its formation to the mature state. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions." [GOC:mtg_cardiac_conduct_nov11, GOC:mtg_heart] is_a: GO:0055013 ! cardiac muscle cell development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 CL:0002072 ! results in development of nodal myocyte relationship: BFO:0000050 GO:0060920 ! part of cardiac pacemaker cell differentiation relationship: RO:0002296 CL:0002072 ! results in development of nodal myocyte creation_date: 2009-09-29T11:51:55Z [Term] id: GO:0060928 name: atrioventricular node cell development namespace: biological_process def: "The process whose specific outcome is the progression of an atrioventricular (AV) node cell over time, from its formation to the mature state." [GOC:mtg_heart] synonym: "AV node cell development" EXACT [GOC:mtg_heart] is_a: GO:0060926 ! cardiac pacemaker cell development intersection_of: GO:0048468 ! cell development intersection_of: RO:0002296 CL:1000410 ! results in development of myocyte of atrioventricular node relationship: BFO:0000050 GO:0060922 ! part of atrioventricular node cell differentiation relationship: RO:0002296 CL:1000410 ! results in development of myocyte of atrioventricular node creation_date: 2009-09-29T11:59:26Z [Term] id: GO:0060931 name: sinoatrial node cell development namespace: biological_process def: "The process whose specific outcome is the progression of a sinoatrial (SA) node cell over time, from its formation to the mature state. SA node cells are pacemaker cells that are found in the sinoatrial node." [GOC:mtg_heart] synonym: "SA node cell development" EXACT [GOC:mtg_heart] synonym: "SAN cell development" EXACT [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] is_a: GO:0060926 ! cardiac pacemaker cell development intersection_of: GO:0048468 ! cell development intersection_of: RO:0002296 CL:1000409 ! results in development of myocyte of sinoatrial node relationship: BFO:0000050 GO:0060921 ! part of sinoatrial node cell differentiation relationship: RO:0002296 CL:1000409 ! results in development of myocyte of sinoatrial node creation_date: 2009-09-29T12:05:47Z [Term] id: GO:0060932 name: His-Purkinje system cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the His-Purkinje system. These cells form the fibers regulate cardiac muscle contraction in the ventricles." [GOC:mtg_heart] is_a: GO:0055007 ! cardiac muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0010007 ! results in acquisition of features of His-Purkinje system cell relationship: BFO:0000050 GO:0003164 ! part of His-Purkinje system development relationship: RO:0002315 CL:0010007 ! results in acquisition of features of His-Purkinje system cell creation_date: 2009-09-29T01:10:32Z [Term] id: GO:0060933 name: His-Purkinje system cell development namespace: biological_process def: "The process whose specific outcome is the progression of a His-Purkinje cell over time, from its formation to the mature state. These cells form the fibers that regulate cardiac muscle contraction in the ventricles." [GOC:mtg_heart] is_a: GO:0055006 ! cardiac cell development intersection_of: GO:0048468 ! cell development intersection_of: RO:0002296 CL:0010007 ! results in development of His-Purkinje system cell relationship: BFO:0000050 GO:0060932 ! part of His-Purkinje system cell differentiation relationship: RO:0002296 CL:0010007 ! results in development of His-Purkinje system cell creation_date: 2009-09-29T01:15:02Z [Term] id: GO:0060935 name: cardiac fibroblast cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules." [GOC:mtg_heart] is_a: GO:0035051 ! cardiocyte differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0002548 ! results in acquisition of features of fibroblast of cardiac tissue relationship: RO:0002315 CL:0002548 ! results in acquisition of features of fibroblast of cardiac tissue creation_date: 2009-09-29T01:20:04Z [Term] id: GO:0060936 name: cardiac fibroblast cell development namespace: biological_process def: "The process whose specific outcome is the progression of a cardiac fibroblast over time, from its formation to the mature state. A cardiac fibroblast is a connective tissue cell of the heart which secretes an extracellular matrix rich in collagen and other macromolecules." [GOC:mtg_heart] is_a: GO:0055006 ! cardiac cell development intersection_of: GO:0048468 ! cell development intersection_of: RO:0002296 CL:0002548 ! results in development of fibroblast of cardiac tissue relationship: BFO:0000050 GO:0060935 ! part of cardiac fibroblast cell differentiation relationship: RO:0002296 CL:0002548 ! results in development of fibroblast of cardiac tissue creation_date: 2009-09-29T01:23:03Z [Term] id: GO:0060945 name: cardiac neuron differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a neuron of the heart." [GOC:mtg_heart] synonym: "heart neuron differentiation" EXACT [GOC:mtg_heart] is_a: GO:0030182 ! neuron differentiation is_a: GO:0035051 ! cardiocyte differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0010022 ! results in acquisition of features of cardiac neuron relationship: BFO:0000050 GO:0048483 ! part of autonomic nervous system development relationship: RO:0002315 CL:0010022 ! results in acquisition of features of cardiac neuron creation_date: 2009-09-29T02:45:33Z [Term] id: GO:0060946 name: cardiac blood vessel endothelial cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell of the heart. Blood vessel endothelial cells are thin flattened cells that line the inside surfaces of blood vessels." [GOC:mtg_heart] is_a: GO:0003348 ! cardiac endothelial cell differentiation is_a: GO:0060837 ! blood vessel endothelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0010006 ! results in acquisition of features of cardiac blood vessel endothelial cell relationship: RO:0002315 CL:0010006 ! results in acquisition of features of cardiac blood vessel endothelial cell creation_date: 2009-09-29T02:48:55Z [Term] id: GO:0060950 name: cardiac glial cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized features of a glial cell of the heart." [GOC:mtg_heart] is_a: GO:0010001 ! glial cell differentiation is_a: GO:0035051 ! cardiocyte differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0010020 ! results in acquisition of features of cardiac glial cell relationship: RO:0002315 CL:0010020 ! results in acquisition of features of cardiac glial cell creation_date: 2009-09-29T03:06:37Z [Term] id: GO:0060952 name: cardiac glial cell development namespace: biological_process def: "The process aimed at the progression of a cardiac glial cell over time, from its formation to the fully functional mature cell." [GOC:mtg_heart] is_a: GO:0021782 ! glial cell development is_a: GO:0055006 ! cardiac cell development intersection_of: GO:0048468 ! cell development intersection_of: RO:0002296 CL:0010020 ! results in development of cardiac glial cell relationship: BFO:0000050 GO:0060950 ! part of cardiac glial cell differentiation relationship: RO:0002296 CL:0010020 ! results in development of cardiac glial cell creation_date: 2009-09-29T03:09:24Z [Term] id: GO:0060956 name: endocardial cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart. The endocardium is the innermost layer of tissue of the heart, and lines the heart chambers." [GOC:mtg_heart] is_a: GO:0003348 ! cardiac endothelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0002350 ! results in acquisition of features of endocardial cell relationship: BFO:0000050 GO:0003157 ! part of endocardium development relationship: RO:0002315 CL:0002350 ! results in acquisition of features of endocardial cell creation_date: 2009-09-29T03:20:39Z [Term] id: GO:0060958 name: endocardial cell development namespace: biological_process def: "The progression of an endocardial cell over time, from its formation to the mature cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart." [GOC:mtg_heart] is_a: GO:0001885 ! endothelial cell development is_a: GO:0055006 ! cardiac cell development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 CL:0002350 ! results in development of endocardial cell relationship: BFO:0000050 GO:0060956 ! part of endocardial cell differentiation relationship: RO:0002296 CL:0002350 ! results in development of endocardial cell creation_date: 2009-09-29T03:26:59Z [Term] id: GO:0060959 name: cardiac neuron development namespace: biological_process def: "The process whose specific outcome is the progression of a cardiac neuron over time, from its formation to the mature state." [GOC:mtg_heart] synonym: "heart neuron development" EXACT [GOC:mtg_heart] is_a: GO:0048666 ! neuron development is_a: GO:0055006 ! cardiac cell development intersection_of: GO:0048468 ! cell development intersection_of: RO:0002296 CL:0010022 ! results in development of cardiac neuron relationship: BFO:0000050 GO:0060945 ! part of cardiac neuron differentiation relationship: RO:0002296 CL:0010022 ! results in development of cardiac neuron creation_date: 2009-09-30T10:14:56Z [Term] id: GO:0060973 name: cell migration involved in heart development namespace: biological_process def: "The orderly movement of a cell from one site to another that will contribute to the progression of the heart over time, from its initial formation, to the mature organ." [GOC:mtg_heart] is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: BFO:0000050 GO:0007507 ! part of heart development relationship: BFO:0000050 GO:0007507 ! part of heart development creation_date: 2009-10-06T10:53:49Z [Term] id: GO:0060974 name: cell migration involved in heart formation namespace: biological_process def: "The orderly movement of a cell from one site to another that contribute to the formation of the heart. The initial heart structure is made up of mesoderm-derived heart progenitor cells and neural crest-derived cells." [GOC:mtg_heart] is_a: GO:0060973 ! cell migration involved in heart development intersection_of: GO:0016477 ! cell migration intersection_of: BFO:0000050 GO:0060914 ! part of heart formation relationship: BFO:0000050 GO:0060914 ! part of heart formation creation_date: 2009-10-06T10:56:33Z [Term] id: GO:0060976 name: coronary vasculature development namespace: biological_process def: "The process whose specific outcome is the progression of the blood vessels of the heart over time, from its formation to the mature structure." [GOC:mtg_heart] synonym: "cardiac blood vessel development" EXACT [GOC:mtg_heart] synonym: "cardiac vasculature development" EXACT [GOC:mtg_heart] synonym: "coronary blood vessel development" EXACT [GOC:mtg_heart] synonym: "heart blood vessel development" EXACT [GOC:mtg_heart] synonym: "heart vasculature development" EXACT [GOC:mtg_heart] is_a: GO:0001568 ! blood vessel development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003498 ! results in development of heart blood vessel relationship: BFO:0000050 GO:0007507 ! part of heart development relationship: RO:0002296 UBERON:0003498 ! results in development of heart blood vessel creation_date: 2009-10-06T12:15:23Z [Term] id: GO:0060977 name: coronary vasculature morphogenesis namespace: biological_process def: "The process in which the anatomical structures of blood vessels of the heart are generated and organized. The blood vessel is the vasculature carrying blood." [GOC:mtg_heart] synonym: "cardiac blood vessel morphogenesis" EXACT [GOC:mtg_heart] synonym: "cardiac vasculature morphogenesis" EXACT [GOC:mtg_heart] synonym: "coronary blood vessel morphogenesis" EXACT [GOC:mtg_heart] synonym: "heart blood vessel morphogenesis" EXACT [GOC:mtg_heart] synonym: "heart vasculature morphogenesis" EXACT [GOC:mtg_heart] is_a: GO:0048514 ! blood vessel morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003498 ! results in morphogenesis of heart blood vessel relationship: BFO:0000050 GO:0060976 ! part of coronary vasculature development relationship: RO:0002298 UBERON:0003498 ! results in morphogenesis of heart blood vessel creation_date: 2009-10-06T12:28:23Z [Term] id: GO:0060978 name: angiogenesis involved in coronary vascular morphogenesis namespace: biological_process def: "Blood vessel formation in the heart when new vessels emerge from the proliferation of pre-existing blood vessels." [GOC:mtg_heart] synonym: "angiogenesis involved in cardiac vascular morphogenesis" EXACT [GOC:mtg_heart] synonym: "angiogenesis involved in heart vascular morphogenesis" EXACT [GOC:mtg_heart] synonym: "coronary blood vessel angiogenesis" EXACT [GOC:mtg_heart] synonym: "coronary vasculature angiogenesis" EXACT [GOC:mtg_heart] is_a: GO:0001525 ! angiogenesis intersection_of: GO:0001525 ! angiogenesis intersection_of: BFO:0000050 GO:0060976 ! part of coronary vasculature development relationship: BFO:0000050 GO:0060977 ! part of coronary vasculature morphogenesis creation_date: 2009-10-06T02:02:12Z [Term] id: GO:0060979 name: vasculogenesis involved in coronary vascular morphogenesis namespace: biological_process def: "The differentiation of endothelial cells from progenitor cells that contributes to blood vessel development in the heart, and the de novo formation of blood vessels and tubes." [GOC:mtg_heart] synonym: "coronary vasculogenesis" EXACT [GOC:mtg_heart] synonym: "vasculogenesis involved in coronary blood vessel morphogenesis" EXACT [GOC:mtg_heart] is_a: GO:0001570 ! vasculogenesis intersection_of: GO:0001570 ! vasculogenesis intersection_of: BFO:0000050 GO:0060977 ! part of coronary vasculature morphogenesis relationship: BFO:0000050 GO:0060977 ! part of coronary vasculature morphogenesis creation_date: 2009-10-06T02:19:42Z [Term] id: GO:0060980 name: cell migration involved in coronary vasculogenesis namespace: biological_process def: "The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form the blood vessels of the heart." [GOC:mtg_heart] is_a: GO:0035441 ! cell migration involved in vasculogenesis is_a: GO:0060973 ! cell migration involved in heart development intersection_of: GO:0016477 ! cell migration intersection_of: BFO:0000050 GO:0060979 ! part of vasculogenesis involved in coronary vascular morphogenesis relationship: BFO:0000050 GO:0060979 ! part of vasculogenesis involved in coronary vascular morphogenesis creation_date: 2009-10-06T02:33:06Z [Term] id: GO:0060981 name: cell migration involved in coronary angiogenesis namespace: biological_process def: "The orderly movement of a cell from one site to another that will contribute to the formation of new blood vessels in the heart from pre-existing blood vessels." [GOC:mtg_heart] is_a: GO:0060973 ! cell migration involved in heart development intersection_of: GO:0016477 ! cell migration intersection_of: BFO:0000050 GO:0060978 ! part of angiogenesis involved in coronary vascular morphogenesis relationship: BFO:0000050 GO:0060978 ! part of angiogenesis involved in coronary vascular morphogenesis creation_date: 2009-10-06T02:49:12Z [Term] id: GO:0060986 name: endocrine hormone secretion namespace: biological_process def: "The regulated release of a hormone into the circulatory system." [GOC:dph] is_a: GO:0046879 ! hormone secretion relationship: BFO:0000050 GO:0050886 ! part of endocrine process creation_date: 2010-01-11T09:03:48Z [Term] id: GO:0060993 name: kidney morphogenesis namespace: biological_process def: "Morphogenesis of a kidney. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:dph, GOC:mtg_kidney_jan10] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002113 ! results in morphogenesis of kidney relationship: BFO:0000050 GO:0001822 ! part of kidney development relationship: RO:0002298 UBERON:0002113 ! results in morphogenesis of kidney creation_date: 2010-01-19T08:16:55Z [Term] id: GO:0060995 name: cell-cell signaling involved in kidney development namespace: biological_process def: "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the kidney over time, from its formation to the mature organ." [GOC:dph, GOC:mtg_kidney_jan10] synonym: "cell-cell signalling involved in kidney development" EXACT [GOC:mah] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: BFO:0000050 GO:0001822 ! part of kidney development relationship: BFO:0000050 GO:0001822 ! part of kidney development creation_date: 2010-01-19T08:33:40Z [Term] id: GO:0061004 name: pattern specification involved in kidney development namespace: biological_process def: "Any developmental process that results in the creation of defined areas or spaces within the kidney to which cells respond and eventually are instructed to differentiate." [GOC:dph, GOC:mtg_kidney_jan10] synonym: "kidney pattern specification" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0007389 ! pattern specification process intersection_of: GO:0007389 ! pattern specification process intersection_of: BFO:0000050 GO:0001822 ! part of kidney development relationship: BFO:0000050 GO:0001822 ! part of kidney development relationship: BFO:0000050 GO:0072048 ! part of renal system pattern specification creation_date: 2010-01-21T09:05:54Z [Term] id: GO:0061005 name: cell differentiation involved in kidney development namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the kidney as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: BFO:0000050 GO:0001822 ! part of kidney development relationship: BFO:0000050 GO:0001822 ! part of kidney development creation_date: 2010-01-21T09:13:55Z [Term] id: GO:0061006 name: regulation of cell proliferation involved in kidney morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell proliferation that contributes to the shaping of the kidney." [GOC:dph, GOC:mtg_kidney_jan10] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0042127 ! regulation of cell population proliferation intersection_of: BFO:0000050 GO:0060993 ! part of kidney morphogenesis relationship: BFO:0000050 GO:0060993 ! part of kidney morphogenesis creation_date: 2010-01-21T11:25:23Z [Term] id: GO:0061007 name: hepaticobiliary system process namespace: biological_process def: "An system process carried out by any of the organs or tissues of the hepaticobiliary system. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins." [GOC:dph] synonym: "hepatobiliary system process" EXACT [GOC:dph] is_a: GO:0003008 ! system process creation_date: 2010-01-22T09:09:10Z [Term] id: GO:0061008 name: hepaticobiliary system development namespace: biological_process def: "The progression of the hepaticobiliary system over time, from its formation to the mature structure. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins." [GOC:dph] synonym: "hepatobiliary system development" EXACT [GOC:dph] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002423 ! results in development of hepatobiliary system relationship: RO:0002296 UBERON:0002423 ! results in development of hepatobiliary system creation_date: 2010-01-22T09:11:59Z [Term] id: GO:0061009 name: common bile duct development namespace: biological_process def: "The progression of the common bile duct over time, from its formation to the mature structure. The common bile duct is formed from the joining of the common hepatic duct running from the liver, and the cystic duct running from the gallbladder. The common bile duct transports bile from the liver and gallbladder to the intestine." [PMID:20614624] synonym: "bile duct development" EXACT [GOC:dph] synonym: "CBD development" EXACT [PMID:20614624] is_a: GO:0035295 ! tube development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002394 ! results in development of bile duct relationship: BFO:0000050 GO:0061008 ! part of hepaticobiliary system development relationship: RO:0002296 UBERON:0002394 ! results in development of bile duct creation_date: 2010-01-22T09:17:13Z [Term] id: GO:0061010 name: gallbladder development namespace: biological_process def: "The progression of the gallbladder over time, from its initial formation to the mature structure. The gallbladder is a cavitated organ that stores bile." [GOC:dph] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002110 ! results in development of gallbladder relationship: BFO:0000050 GO:0061008 ! part of hepaticobiliary system development relationship: RO:0002296 UBERON:0002110 ! results in development of gallbladder creation_date: 2010-01-22T09:38:44Z [Term] id: GO:0061011 name: hepatic duct development namespace: biological_process def: "The progression of the hepatic duct over time, from its formation to the mature structure. The hepatic duct is the duct that leads from the liver to the common bile duct." [GOC:dph, PMID:20614624] is_a: GO:0061009 ! common bile duct development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001175 ! results in development of common hepatic duct relationship: RO:0002296 UBERON:0001175 ! results in development of common hepatic duct creation_date: 2010-01-22T09:44:39Z [Term] id: GO:0061017 name: hepatoblast differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a hepatoblast. A hepatoblast is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into hepatocytes and cholangiocytes." [GOC:dph, PMID:15226394] is_a: GO:0030855 ! epithelial cell differentiation is_a: GO:0048863 ! stem cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:1000488 ! results in acquisition of features of cholangiocyte relationship: BFO:0000050 GO:0001889 ! part of liver development relationship: RO:0002315 CL:1000488 ! results in acquisition of features of cholangiocyte creation_date: 2010-02-02T09:08:03Z [Term] id: GO:0061024 name: membrane organization namespace: biological_process def: "A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins." [GOC:dph, GOC:tb] synonym: "cellular membrane organisation" EXACT [] synonym: "cellular membrane organization" EXACT [] synonym: "membrane organisation" EXACT [GOC:mah] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0016020 ! results in organization of membrane relationship: RO:0002592 GO:0016020 ! results in organization of membrane creation_date: 2010-02-08T02:43:11Z [Term] id: GO:0061025 name: membrane fusion namespace: biological_process def: "The membrane organization process that joins two lipid bilayers to form a single membrane." [GOC:dph, GOC:tb] synonym: "cellular membrane fusion" EXACT [] xref: Wikipedia:Lipid_bilayer_fusion is_a: GO:0061024 ! membrane organization intersection_of: GO:0061024 ! membrane organization intersection_of: RO:0012008 GO:0016020 ! results in fusion of membrane relationship: RO:0012008 GO:0016020 ! results in fusion of membrane creation_date: 2010-02-08T02:48:06Z [Term] id: GO:0061027 name: umbilical cord development namespace: biological_process def: "The process whose specific outcome is the development of the umbilical cord, from its formation to the mature structure. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta." [GOC:BHF, GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002331 ! results in development of umbilical cord relationship: RO:0002296 UBERON:0002331 ! results in development of umbilical cord creation_date: 2010-02-09T09:09:22Z [Term] id: GO:0061032 name: visceral serous pericardium development namespace: biological_process def: "The progression of the visceral serous pericardium from its formation to the mature structure. The visceral serous pericardium is the inner layer of the pericardium." [GOC:dph, GOC:yaf] synonym: "epicardium development" EXACT [GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002425 ! results in development of visceral serous pericardium relationship: BFO:0000050 GO:0060039 ! part of pericardium development relationship: RO:0002296 UBERON:0002425 ! results in development of visceral serous pericardium creation_date: 2010-02-09T09:52:49Z [Term] id: GO:0061035 name: regulation of cartilage development namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." [GOC:dph] is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0051216 ! regulates (processual) cartilage development relationship: RO:0002211 GO:0051216 ! regulates (processual) cartilage development creation_date: 2010-02-09T03:41:35Z [Term] id: GO:0061036 name: positive regulation of cartilage development namespace: biological_process def: "Any process that increases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." [GOC:dph] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:0061035 ! regulation of cartilage development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0051216 ! positively regulates cartilage development relationship: RO:0002213 GO:0051216 ! positively regulates cartilage development creation_date: 2010-02-09T03:41:35Z [Term] id: GO:0061037 name: negative regulation of cartilage development namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." [GOC:dph] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:0061035 ! regulation of cartilage development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0051216 ! negatively regulates cartilage development relationship: RO:0002212 GO:0051216 ! negatively regulates cartilage development creation_date: 2010-02-09T03:41:35Z [Term] id: GO:0061038 name: uterus morphogenesis namespace: biological_process def: "The process in which anatomical structures of the uterus are generated and organized." [GOC:BHF, GOC:dph] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000995 ! results in morphogenesis of uterus relationship: BFO:0000050 GO:0060065 ! part of uterus development relationship: RO:0002298 UBERON:0000995 ! results in morphogenesis of uterus creation_date: 2010-02-22T11:12:35Z [Term] id: GO:0061040 name: female gonad morphogenesis namespace: biological_process def: "The process in which a female gonad is generated and organized." [GOC:BHF, GOC:dph] is_a: GO:0035262 ! gonad morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000992 ! results in morphogenesis of ovary relationship: BFO:0000050 GO:0008585 ! part of female gonad development relationship: RO:0002298 UBERON:0000992 ! results in morphogenesis of ovary creation_date: 2010-02-22T11:29:28Z [Term] id: GO:0061046 name: regulation of branching involved in lung morphogenesis namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units." [GOC:dph, GOC:yaf] is_a: GO:0060688 ! regulation of morphogenesis of a branching structure is_a: GO:1905330 ! regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060441 ! regulates (processual) epithelial tube branching involved in lung morphogenesis relationship: RO:0002211 GO:0060441 ! regulates (processual) epithelial tube branching involved in lung morphogenesis creation_date: 2010-02-25T10:41:38Z [Term] id: GO:0061047 name: positive regulation of branching involved in lung morphogenesis namespace: biological_process def: "Any process that increases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units." [GOC:dph, GOC:yaf] is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:0061046 ! regulation of branching involved in lung morphogenesis is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060441 ! positively regulates epithelial tube branching involved in lung morphogenesis relationship: RO:0002213 GO:0060441 ! positively regulates epithelial tube branching involved in lung morphogenesis creation_date: 2010-02-25T10:50:01Z [Term] id: GO:0061048 name: negative regulation of branching involved in lung morphogenesis namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units." [GOC:dph, GOC:yaf] is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:0061046 ! regulation of branching involved in lung morphogenesis is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060441 ! negatively regulates epithelial tube branching involved in lung morphogenesis relationship: RO:0002212 GO:0060441 ! negatively regulates epithelial tube branching involved in lung morphogenesis creation_date: 2010-02-25T10:51:31Z [Term] id: GO:0061049 name: cell growth involved in cardiac muscle cell development namespace: biological_process def: "The growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state." [GOC:dph] is_a: GO:0048588 ! developmental cell growth intersection_of: GO:0016049 ! cell growth intersection_of: BFO:0000050 GO:0055013 ! part of cardiac muscle cell development relationship: BFO:0000050 GO:0003301 ! part of physiological cardiac muscle hypertrophy relationship: BFO:0000050 GO:0055013 ! part of cardiac muscle cell development creation_date: 2010-02-25T12:56:07Z [Term] id: GO:0061050 name: regulation of cell growth involved in cardiac muscle cell development namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state." [GOC:dph] is_a: GO:0001558 ! regulation of cell growth is_a: GO:0055021 ! regulation of cardiac muscle tissue growth intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0061049 ! regulates (processual) cell growth involved in cardiac muscle cell development relationship: RO:0002211 GO:0061049 ! regulates (processual) cell growth involved in cardiac muscle cell development creation_date: 2010-02-25T01:05:16Z [Term] id: GO:0061051 name: positive regulation of cell growth involved in cardiac muscle cell development namespace: biological_process def: "Any process that increases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state." [GOC:dph] is_a: GO:0010613 ! positive regulation of cardiac muscle hypertrophy is_a: GO:0030307 ! positive regulation of cell growth is_a: GO:0051155 ! positive regulation of striated muscle cell differentiation is_a: GO:0055023 ! positive regulation of cardiac muscle tissue growth is_a: GO:0061050 ! regulation of cell growth involved in cardiac muscle cell development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0061049 ! positively regulates cell growth involved in cardiac muscle cell development relationship: RO:0002213 GO:0061049 ! positively regulates cell growth involved in cardiac muscle cell development creation_date: 2010-02-25T01:08:08Z [Term] id: GO:0061052 name: negative regulation of cell growth involved in cardiac muscle cell development namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state." [GOC:dph] is_a: GO:0010614 ! negative regulation of cardiac muscle hypertrophy is_a: GO:0030308 ! negative regulation of cell growth is_a: GO:0051154 ! negative regulation of striated muscle cell differentiation is_a: GO:0055022 ! negative regulation of cardiac muscle tissue growth is_a: GO:0061050 ! regulation of cell growth involved in cardiac muscle cell development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0061049 ! negatively regulates cell growth involved in cardiac muscle cell development relationship: RO:0002212 GO:0061049 ! negatively regulates cell growth involved in cardiac muscle cell development creation_date: 2010-02-25T01:11:30Z [Term] id: GO:0061053 name: somite development namespace: biological_process def: "The progression of a somite from its initial formation to the mature structure. Somites are mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo." [GOC:dph] is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002329 ! results in development of somite relationship: BFO:0000050 GO:0009790 ! part of embryo development relationship: RO:0002296 UBERON:0002329 ! results in development of somite creation_date: 2010-03-02T12:05:13Z [Term] id: GO:0061054 name: dermatome development namespace: biological_process def: "The progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin." [GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004016 ! results in development of dermatome relationship: BFO:0000050 GO:0061053 ! part of somite development relationship: RO:0002296 UBERON:0004016 ! results in development of dermatome creation_date: 2010-03-02T12:07:37Z [Term] id: GO:0061055 name: myotome development namespace: biological_process def: "The progression of the myotome over time, from its formation to the mature structure. The myotome is the portion of the somite that will give rise to muscle." [GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003082 ! results in development of myotome relationship: BFO:0000050 GO:0061053 ! part of somite development relationship: RO:0002296 UBERON:0003082 ! results in development of myotome creation_date: 2010-03-02T12:11:01Z [Term] id: GO:0061056 name: sclerotome development namespace: biological_process def: "The progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra." [GOC:dph] is_a: GO:0060485 ! mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003089 ! results in development of sclerotome relationship: BFO:0000050 GO:0061053 ! part of somite development relationship: RO:0002296 UBERON:0003089 ! results in development of sclerotome creation_date: 2010-03-02T12:12:40Z [Term] id: GO:0061061 name: muscle structure development namespace: biological_process def: "The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms." [GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005090 ! results in development of muscle structure relationship: RO:0002160 NCBITaxon:6072 ! only in taxon Eumetazoa relationship: RO:0002162 NCBITaxon:6072 {all_only="true"} ! in taxon Eumetazoa relationship: RO:0002296 UBERON:0005090 ! results in development of muscle structure creation_date: 2010-03-09T08:55:14Z [Term] id: GO:0061062 name: regulation of nematode larval development namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew." [GOC:dph, GOC:kmv] is_a: GO:0048580 ! regulation of post-embryonic development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002119 ! regulates (processual) nematode larval development relationship: RO:0002211 GO:0002119 ! regulates (processual) nematode larval development creation_date: 2010-03-11T12:59:21Z [Term] id: GO:0061063 name: positive regulation of nematode larval development namespace: biological_process def: "Any process that increases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew." [GOC:dph, GOC:kmv] is_a: GO:0048582 ! positive regulation of post-embryonic development is_a: GO:0061062 ! regulation of nematode larval development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002119 ! positively regulates nematode larval development relationship: RO:0002213 GO:0002119 ! positively regulates nematode larval development creation_date: 2010-03-11T01:03:34Z [Term] id: GO:0061064 name: negative regulation of nematode larval development namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew." [GOC:dph, GOC:kmv] is_a: GO:0048581 ! negative regulation of post-embryonic development is_a: GO:0061062 ! regulation of nematode larval development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002119 ! negatively regulates nematode larval development relationship: RO:0002212 GO:0002119 ! negatively regulates nematode larval development creation_date: 2010-03-11T01:04:39Z [Term] id: GO:0061068 name: urethra development namespace: biological_process def: "The progression of the urethra over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body." [GOC:dph] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000057 ! results in development of urethra relationship: BFO:0000050 GO:0072001 ! part of renal system development relationship: RO:0002296 UBERON:0000057 ! results in development of urethra creation_date: 2010-03-12T08:24:52Z [Term] id: GO:0061069 name: male urethra development namespace: biological_process def: "The progression of the male urethra over time from its initial formation to the mature structure. The male urethra is a renal system organ that carries urine from the bladder through the penis to outside the body." [GOC:dph] is_a: GO:0061068 ! urethra development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001333 ! results in development of male urethra relationship: RO:0002296 UBERON:0001333 ! results in development of male urethra creation_date: 2010-03-12T08:28:19Z [Term] id: GO:0061070 name: female urethra development namespace: biological_process def: "The progression of the female urethra over time from its initial formation to the mature structure. The female urethra is a renal system organ that carries urine from the bladder to outside the body, exiting above the vaginal opening." [GOC:dph] is_a: GO:0061068 ! urethra development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001334 ! results in development of female urethra relationship: RO:0002296 UBERON:0001334 ! results in development of female urethra creation_date: 2010-03-12T08:29:43Z [Term] id: GO:0061071 name: urethra epithelium development namespace: biological_process def: "The progression of the urethra epithelium over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body. The epithelium is the tubular, planar layer of cells through which the urine passes." [GOC:dph] is_a: GO:0035295 ! tube development is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002325 ! results in development of epithelium of urethra relationship: BFO:0000050 GO:0061068 ! part of urethra development relationship: RO:0002296 UBERON:0002325 ! results in development of epithelium of urethra creation_date: 2010-03-12T08:36:53Z [Term] id: GO:0061072 name: iris morphogenesis namespace: biological_process def: "The process in which the iris is generated and organized. The iris is an anatomical structure in the eye whose opening forms the pupil. The iris is responsible for controlling the diameter and size of the pupil and the amount of light reaching the retina." [GOC:dph] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001769 ! results in morphogenesis of iris relationship: BFO:0000050 GO:0048593 ! part of camera-type eye morphogenesis relationship: RO:0002298 UBERON:0001769 ! results in morphogenesis of iris creation_date: 2010-03-16T10:48:42Z [Term] id: GO:0061073 name: ciliary body morphogenesis namespace: biological_process def: "The process in which the ciliary body generated and organized. The ciliary body is the circumferential tissue inside the eye composed of the ciliary muscle and ciliary processes." [GOC:dph] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001775 ! results in morphogenesis of ciliary body relationship: BFO:0000050 GO:0048593 ! part of camera-type eye morphogenesis relationship: RO:0002298 UBERON:0001775 ! results in morphogenesis of ciliary body creation_date: 2010-03-16T10:55:19Z [Term] id: GO:0061074 name: regulation of neural retina development namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells." [GOC:dph] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003407 ! regulates (processual) neural retina development relationship: RO:0002211 GO:0003407 ! regulates (processual) neural retina development creation_date: 2010-03-16T11:47:05Z [Term] id: GO:0061075 name: positive regulation of neural retina development namespace: biological_process def: "Any process that increases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells." [GOC:dph] is_a: GO:0061074 ! regulation of neural retina development is_a: GO:1902868 ! positive regulation of retina development in camera-type eye intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0003407 ! positively regulates neural retina development relationship: RO:0002213 GO:0003407 ! positively regulates neural retina development creation_date: 2010-03-16T11:59:48Z [Term] id: GO:0061076 name: negative regulation of neural retina development namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells." [GOC:dph] is_a: GO:0061074 ! regulation of neural retina development is_a: GO:1902867 ! negative regulation of retina development in camera-type eye intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0003407 ! negatively regulates neural retina development relationship: RO:0002212 GO:0003407 ! negatively regulates neural retina development creation_date: 2010-03-16T12:46:11Z [Term] id: GO:0061080 name: right horn of sinus venosus development namespace: biological_process def: "The progression of the right horn of the sinus venosus from its formation to the mature structure." [GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005092 ! results in development of right horn of sinus venosus relationship: BFO:0000050 GO:0003235 ! part of sinus venosus development relationship: RO:0002296 UBERON:0005092 ! results in development of right horn of sinus venosus creation_date: 2010-04-08T02:45:10Z [Term] id: GO:0061100 name: lung neuroendocrine cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the lung epithelium." [GOC:dph, PMID:9126746] is_a: GO:0061101 ! neuroendocrine cell differentiation is_a: GO:0061140 ! lung secretory cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:1000223 ! results in acquisition of features of lung neuroendocrine cell relationship: RO:0002315 CL:1000223 ! results in acquisition of features of lung neuroendocrine cell creation_date: 2010-04-27T03:28:46Z [Term] id: GO:0061101 name: neuroendocrine cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a neuroendocrine cell. A neuroendocrine cell is a cell that receives input form a neuron which controls the secretion of an endocrine substance." [GOC:dph] is_a: GO:0030182 ! neuron differentiation is_a: GO:0060563 ! neuroepithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000165 ! results in acquisition of features of neuroendocrine cell relationship: RO:0002315 CL:0000165 ! results in acquisition of features of neuroendocrine cell creation_date: 2010-04-28T09:42:20Z [Term] id: GO:0061102 name: stomach neuroendocrine cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the stomach epithelium." [GOC:dph, PMID:18173746] is_a: GO:0035883 ! enteroendocrine cell differentiation is_a: GO:0061101 ! neuroendocrine cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:1000222 ! results in acquisition of features of stomach neuroendocrine cell relationship: BFO:0000050 GO:0062094 ! part of stomach development relationship: RO:0002315 CL:1000222 ! results in acquisition of features of stomach neuroendocrine cell creation_date: 2010-04-28T09:47:07Z [Term] id: GO:0061105 name: regulation of stomach neuroendocrine cell differentiation namespace: biological_process def: "Any process that modulates the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach." [GOC:dph] is_a: GO:0030856 ! regulation of epithelial cell differentiation is_a: GO:0045664 ! regulation of neuron differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0061102 ! regulates (processual) stomach neuroendocrine cell differentiation relationship: RO:0002211 GO:0061102 ! regulates (processual) stomach neuroendocrine cell differentiation creation_date: 2010-04-29T12:19:37Z [Term] id: GO:0061106 name: negative regulation of stomach neuroendocrine cell differentiation namespace: biological_process def: "Any process that decreases the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach." [GOC:dph] is_a: GO:0002085 ! inhibition of neuroepithelial cell differentiation is_a: GO:0045665 ! negative regulation of neuron differentiation is_a: GO:0061105 ! regulation of stomach neuroendocrine cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0061102 ! negatively regulates stomach neuroendocrine cell differentiation relationship: RO:0002212 GO:0061102 ! negatively regulates stomach neuroendocrine cell differentiation creation_date: 2010-04-29T12:23:05Z [Term] id: GO:0061107 name: seminal vesicle development namespace: biological_process def: "The progression of the seminal vesicle over time, from its formation to the mature structure. The seminal vesicle is a gland that contributes to the production of semen." [GOC:dph] is_a: GO:0048608 ! reproductive structure development is_a: GO:0048732 ! gland development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000998 ! results in development of seminal vesicle relationship: RO:0002296 UBERON:0000998 ! results in development of seminal vesicle creation_date: 2010-04-30T10:17:30Z [Term] id: GO:0061108 name: seminal vesicle epithelium development namespace: biological_process def: "The progression of the seminal vesicle epithelium over time, from its formation to the mature structure." [GOC:dph] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0035295 ! tube development is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004805 ! results in development of seminal vesicle epithelium relationship: BFO:0000050 GO:0061107 ! part of seminal vesicle development relationship: RO:0002296 UBERON:0004805 ! results in development of seminal vesicle epithelium creation_date: 2010-04-30T10:19:54Z [Term] id: GO:0061109 name: dense core granule organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a dense core granule. A dense core granule is a secretory organelle found in endocrine cells." [GOC:dph] synonym: "dense core granule organisation" EXACT [GOC:mah] is_a: GO:0033363 ! secretory granule organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0031045 ! results in organization of dense core granule relationship: RO:0002592 GO:0031045 ! results in organization of dense core granule creation_date: 2010-05-01T09:34:37Z [Term] id: GO:0061111 name: epithelial-mesenchymal cell signaling involved in lung development namespace: biological_process def: "Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell and contributes to the progression of the lung over time from its initial formation to the mature organ." [GOC:dph] synonym: "epithelial-mesenchymal cell signalling involved in lung development" EXACT [GOC:mah] is_a: GO:0060495 ! cell-cell signaling involved in lung development is_a: GO:0060684 ! epithelial-mesenchymal cell signaling intersection_of: GO:0060684 ! epithelial-mesenchymal cell signaling intersection_of: BFO:0000050 GO:0030324 ! part of lung development creation_date: 2010-05-05T11:14:38Z [Term] id: GO:0061113 name: pancreas morphogenesis namespace: biological_process def: "Morphogenesis of the pancreas. Morphogenesis is the process in which anatomical structures are generated and organized." [GOC:dph] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001264 ! results in morphogenesis of pancreas relationship: BFO:0000050 GO:0031016 ! part of pancreas development relationship: RO:0002298 UBERON:0001264 ! results in morphogenesis of pancreas creation_date: 2010-05-05T11:55:30Z [Term] id: GO:0061114 name: branching involved in pancreas morphogenesis namespace: biological_process def: "The process in which the branches of the pancreas are generated and organized." [GOC:dph] is_a: GO:0061138 ! morphogenesis of a branching epithelium intersection_of: GO:0061138 ! morphogenesis of a branching epithelium intersection_of: BFO:0000050 GO:0061113 ! part of pancreas morphogenesis relationship: BFO:0000050 GO:0061113 ! part of pancreas morphogenesis creation_date: 2010-05-05T12:03:04Z [Term] id: GO:0061117 name: negative regulation of heart growth namespace: biological_process def: "Any process that decreases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart." [GOC:dph, GOC:hjd] is_a: GO:0046621 ! negative regulation of organ growth is_a: GO:0060420 ! regulation of heart growth intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060419 ! negatively regulates heart growth relationship: RO:0002212 GO:0060419 ! negatively regulates heart growth creation_date: 2010-05-17T07:31:28Z [Term] id: GO:0061130 name: pancreatic bud formation namespace: biological_process def: "The morphogenetic process in which the foregut region specified to become the pancreas forms a bud." [GOC:dph] is_a: GO:0048645 ! animal organ formation is_a: GO:0061114 ! branching involved in pancreas morphogenesis is_a: GO:0072175 ! epithelial tube formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0003922 ! results in formation of anatomical entity pancreatic epithelial bud relationship: RO:0002297 UBERON:0003922 ! results in formation of anatomical entity pancreatic epithelial bud creation_date: 2010-05-17T09:33:40Z [Term] id: GO:0061138 name: morphogenesis of a branching epithelium namespace: biological_process def: "The process in which the anatomical structures of a branched epithelium are generated and organized." [GOC:dph] is_a: GO:0001763 ! morphogenesis of a branching structure is_a: GO:0002009 ! morphogenesis of an epithelium creation_date: 2010-05-25T09:05:34Z [Term] id: GO:0061140 name: lung secretory cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a lung secretory cell. A lung secretory cell is a specialized epithelial cell of the lung that contains large secretory granules in its apical part." [GOC:dph] is_a: GO:0060487 ! lung epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:1000272 ! results in acquisition of features of lung secretory cell relationship: RO:0002315 CL:1000272 ! results in acquisition of features of lung secretory cell creation_date: 2010-05-25T09:28:53Z [Term] id: GO:0061141 name: lung ciliated cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a lung ciliated cell. A lung ciliated cell is a specialized lung epithelial cell that contains cilia for moving substances released from lung secretory cells." [GOC:cilia, GOC:dph, GOC:krc] is_a: GO:0060487 ! lung epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:1000271 ! results in acquisition of features of lung ciliated cell relationship: RO:0002315 CL:1000271 ! results in acquisition of features of lung ciliated cell creation_date: 2010-05-25T09:31:14Z [Term] id: GO:0061147 name: endocardial endothelium development namespace: biological_process def: "The progression of the endocardial endothelium over time, from its initial formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers." [GOC:dph] is_a: GO:0003158 ! endothelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005316 ! results in development of endocardial endothelium relationship: BFO:0000050 GO:0003157 ! part of endocardium development relationship: RO:0002296 UBERON:0005316 ! results in development of endocardial endothelium creation_date: 2010-06-03T09:15:31Z [Term] id: GO:0061148 name: extracellular matrix organization involved in endocardium development namespace: biological_process def: "A process which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix of the endocardium. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers." [GOC:dph] synonym: "extracellular matrix organisation involved in endocardium development" EXACT [GOC:mah] is_a: GO:0030198 ! extracellular matrix organization intersection_of: GO:0030198 ! extracellular matrix organization intersection_of: BFO:0000050 GO:0003157 ! part of endocardium development relationship: BFO:0000050 GO:0003157 ! part of endocardium development creation_date: 2010-06-03T09:18:02Z [Term] id: GO:0061154 name: endothelial tube morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a tube are generated and organized from an endothelium. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells." [GOC:dph, GOC:yaf] is_a: GO:0003159 ! morphogenesis of an endothelium is_a: GO:0060562 ! epithelial tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003915 ! results in morphogenesis of endothelial tube relationship: RO:0002298 UBERON:0003915 ! results in morphogenesis of endothelial tube creation_date: 2010-06-15T09:05:00Z [Term] id: GO:0061155 name: pulmonary artery endothelial tube morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a tube are generated and organized from the pulmonary artery endothelium. An pulmonary artery endothelium is an epithelium that lines the pulmonary artery." [GOC:dph, GOC:yaf] is_a: GO:0061154 ! endothelial tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0005317 ! results in morphogenesis of pulmonary artery endothelium relationship: BFO:0000050 GO:0061156 ! part of pulmonary artery morphogenesis relationship: RO:0002298 UBERON:0005317 ! results in morphogenesis of pulmonary artery endothelium creation_date: 2010-06-15T09:09:04Z [Term] id: GO:0061156 name: pulmonary artery morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the pulmonary artery are generated and organized. The pulmonary artery is the artery that carries blood from the heart to the lungs." [GOC:dph, GOC:yaf] is_a: GO:0048844 ! artery morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002012 ! results in morphogenesis of pulmonary artery relationship: RO:0002298 UBERON:0002012 ! results in morphogenesis of pulmonary artery creation_date: 2010-06-15T09:13:47Z [Term] id: GO:0061181 name: regulation of chondrocyte development namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate." [GOC:BHF, GOC:dph] is_a: GO:0032330 ! regulation of chondrocyte differentiation is_a: GO:0060284 ! regulation of cell development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002063 ! regulates (processual) chondrocyte development relationship: RO:0002211 GO:0002063 ! regulates (processual) chondrocyte development creation_date: 2010-07-14T08:28:52Z [Term] id: GO:0061182 name: negative regulation of chondrocyte development namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate." [GOC:BHF, GOC:dph] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0032331 ! negative regulation of chondrocyte differentiation is_a: GO:0061181 ! regulation of chondrocyte development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002063 ! negatively regulates chondrocyte development relationship: RO:0002212 GO:0002063 ! negatively regulates chondrocyte development creation_date: 2010-07-14T08:33:05Z [Term] id: GO:0061183 name: regulation of dermatome development namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin." [GOC:BHF, GOC:dph] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0061054 ! regulates (processual) dermatome development relationship: RO:0002211 GO:0061054 ! regulates (processual) dermatome development creation_date: 2010-07-14T08:40:26Z [Term] id: GO:0061184 name: positive regulation of dermatome development namespace: biological_process def: "Any process that increases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin." [GOC:BHF, GOC:dph] is_a: GO:0040019 ! positive regulation of embryonic development is_a: GO:0061183 ! regulation of dermatome development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0061054 ! positively regulates dermatome development relationship: RO:0002213 GO:0061054 ! positively regulates dermatome development creation_date: 2010-07-14T08:42:03Z [Term] id: GO:0061185 name: negative regulation of dermatome development namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin." [GOC:BHF, GOC:dph] is_a: GO:0045992 ! negative regulation of embryonic development is_a: GO:0061183 ! regulation of dermatome development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0061054 ! negatively regulates dermatome development relationship: RO:0002212 GO:0061054 ! negatively regulates dermatome development creation_date: 2010-07-14T08:43:08Z [Term] id: GO:0061189 name: positive regulation of sclerotome development namespace: biological_process def: "Any process that increases the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra." [GOC:BHF, GOC:dph] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0061190 ! regulation of sclerotome development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0061056 ! positively regulates sclerotome development relationship: RO:0002213 GO:0061056 ! positively regulates sclerotome development creation_date: 2010-07-14T09:17:23Z [Term] id: GO:0061190 name: regulation of sclerotome development namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra." [GOC:dph] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0061056 ! regulates (processual) sclerotome development relationship: RO:0002211 GO:0061056 ! regulates (processual) sclerotome development creation_date: 2010-07-14T09:19:47Z [Term] id: GO:0061205 name: paramesonephric duct development namespace: biological_process def: "The process whose specific outcome is the progression of the paramesonephric duct over time, from its formation to the mature structure. Mullerian ducts (or paramesonephric ducts) are paired ducts of the embryo that run down the lateral sides of the urogenital ridge and terminate at the mullerian eminence in the primitive urogenital sinus. In the female, they will develop to form the fallopian tubes, uterus, cervix, and the upper portion of the vagina; in the male, they are lost. These ducts are made of tissue of mesodermal origin." [GOC:dph, GOC:yaf] synonym: "Mullerian duct development" EXACT [GOC:dph] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0035295 ! tube development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003890 ! results in development of Mullerian duct relationship: RO:0002296 UBERON:0003890 ! results in development of Mullerian duct creation_date: 2010-07-30T10:54:47Z [Term] id: GO:0061206 name: mesonephros morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the mesonephros are generated and organized." [GOC:mtg_kidney_jan10] synonym: "Wolffian body morphogenesis" EXACT [GOC:dph] is_a: GO:0060993 ! kidney morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000080 ! results in morphogenesis of mesonephros relationship: BFO:0000050 GO:0001823 ! part of mesonephros development relationship: RO:0002298 UBERON:0000080 ! results in morphogenesis of mesonephros creation_date: 2010-08-17T03:11:10Z [Term] id: GO:0061208 name: cell differentiation involved in mesonephros development namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephros as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] is_a: GO:0061005 ! cell differentiation involved in kidney development intersection_of: GO:0030154 ! cell differentiation intersection_of: BFO:0000050 GO:0001823 ! part of mesonephros development relationship: BFO:0000050 GO:0001823 ! part of mesonephros development creation_date: 2010-08-17T03:21:23Z [Term] id: GO:0061209 name: cell proliferation involved in mesonephros development namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of the population in the mesonephros." [GOC:mtg_kidney_jan10] is_a: GO:0072111 ! cell proliferation involved in kidney development intersection_of: GO:0008283 ! cell population proliferation intersection_of: BFO:0000050 GO:0001823 ! part of mesonephros development relationship: BFO:0000050 GO:0001823 ! part of mesonephros development creation_date: 2010-08-17T03:22:46Z [Term] id: GO:0061210 name: cell-cell signaling involved in mesonephros development namespace: biological_process def: "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mesonephros over time, from its formation to the mature organ." [GOC:mtg_kidney_jan10] synonym: "cell-cell signalling involved in mesonephros development" EXACT [GOC:mah] is_a: GO:0060995 ! cell-cell signaling involved in kidney development intersection_of: GO:0007267 ! cell-cell signaling intersection_of: BFO:0000050 GO:0001823 ! part of mesonephros development relationship: BFO:0000050 GO:0001823 ! part of mesonephros development creation_date: 2010-08-17T03:24:08Z [Term] id: GO:0061211 name: mesonephric collecting duct development namespace: biological_process def: "The process whose specific outcome is the progression of a collecting duct in the mesonephros over time, from its formation to the mature structure. The collecting duct regulates water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder." [GOC:mtg_kidney_jan10] is_a: GO:0072044 ! collecting duct development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005319 ! results in development of mesonephric collecting duct relationship: BFO:0000050 GO:0001823 ! part of mesonephros development relationship: RO:0002296 UBERON:0005319 ! results in development of mesonephric collecting duct creation_date: 2010-08-17T03:25:51Z [Term] id: GO:0061213 name: positive regulation of mesonephros development namespace: biological_process def: "Any process that increases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10] is_a: GO:0061217 ! regulation of mesonephros development is_a: GO:0090184 ! positive regulation of kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001823 ! positively regulates mesonephros development relationship: RO:0002213 GO:0001823 ! positively regulates mesonephros development creation_date: 2010-08-17T03:39:35Z [Term] id: GO:0061214 name: mesonephric smooth muscle tissue development namespace: biological_process def: "The process whose specific outcome is the progression of smooth muscle in the mesonephros over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10] is_a: GO:0072194 ! kidney smooth muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005321 ! results in development of mesonephric smooth muscle tissue relationship: BFO:0000050 GO:0001823 ! part of mesonephros development relationship: RO:0002296 UBERON:0005321 ! results in development of mesonephric smooth muscle tissue creation_date: 2010-08-17T03:29:54Z [Term] id: GO:0061215 name: mesonephric nephron development namespace: biological_process def: "The process whose specific outcome is the progression of a nephron in the mesonephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney." [GOC:mtg_kidney_jan10] is_a: GO:0072006 ! nephron development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005322 ! results in development of mesonephric nephron relationship: BFO:0000050 GO:0001823 ! part of mesonephros development relationship: RO:0002296 UBERON:0005322 ! results in development of mesonephric nephron creation_date: 2010-08-17T03:31:08Z [Term] id: GO:0061217 name: regulation of mesonephros development namespace: biological_process def: "Any process that modulates the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10] is_a: GO:0090183 ! regulation of kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001823 ! regulates (processual) mesonephros development relationship: RO:0002211 GO:0001823 ! regulates (processual) mesonephros development creation_date: 2010-08-17T03:35:31Z [Term] id: GO:0061218 name: negative regulation of mesonephros development namespace: biological_process def: "Any process that decreases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10] is_a: GO:0061217 ! regulation of mesonephros development is_a: GO:0090185 ! negative regulation of kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001823 ! negatively regulates mesonephros development relationship: RO:0002212 GO:0001823 ! negatively regulates mesonephros development creation_date: 2010-08-17T03:43:06Z [Term] id: GO:0061219 name: mesonephric mesenchyme development namespace: biological_process def: "The biological process whose specific outcome is the progression of a mesonephric mesenchyme from an initial condition to its mature state. This process begins with the formation of mesonephric mesenchyme and ends with the mature structure. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros." [GOC:mtg_kidney_jan10] is_a: GO:0072074 ! kidney mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005323 ! results in development of mesonephric mesenchyme relationship: BFO:0000050 GO:0001823 ! part of mesonephros development relationship: RO:0002296 UBERON:0005323 ! results in development of mesonephric mesenchyme creation_date: 2010-08-17T03:45:44Z [Term] id: GO:0061221 name: mesonephric mesenchyme morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a mesonephric mesenchymal tissue are generated and organized. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros." [GOC:mtg_kidney_jan10] is_a: GO:0072131 ! kidney mesenchyme morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0005323 ! results in morphogenesis of mesonephric mesenchyme relationship: BFO:0000050 GO:0061219 ! part of mesonephric mesenchyme development relationship: RO:0002298 UBERON:0005323 ! results in morphogenesis of mesonephric mesenchyme creation_date: 2010-08-19T01:17:38Z [Term] id: GO:0061227 name: pattern specification involved in mesonephros development namespace: biological_process def: "Any developmental process that results in the creation of defined areas or spaces within the mesonephros to which cells respond and eventually are instructed to differentiate." [GOC:mtg_kidney_jan10] synonym: "mesonephros pattern specification" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0061004 ! pattern specification involved in kidney development intersection_of: GO:0007389 ! pattern specification process intersection_of: BFO:0000050 GO:0001823 ! part of mesonephros development relationship: BFO:0000050 GO:0001823 ! part of mesonephros development creation_date: 2010-08-19T02:22:22Z [Term] id: GO:0061228 name: mesonephric nephron morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the mesonephric nephron are generated and organized. A mesonephric nephron is the functional unit of the mesonephros." [GOC:mtg_kidney_jan10] is_a: GO:0072028 ! nephron morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0005322 ! results in morphogenesis of mesonephric nephron relationship: BFO:0000050 GO:0061206 ! part of mesonephros morphogenesis relationship: BFO:0000050 GO:0061215 ! part of mesonephric nephron development relationship: RO:0002298 UBERON:0005322 ! results in morphogenesis of mesonephric nephron creation_date: 2010-08-19T02:26:24Z [Term] id: GO:0061235 name: mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis namespace: biological_process def: "The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the mesonephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells." [GOC:mtg_kidney_jan10] is_a: GO:0072038 ! mesenchymal stem cell maintenance involved in nephron morphogenesis relationship: BFO:0000050 GO:0061228 ! part of mesonephric nephron morphogenesis creation_date: 2010-08-19T02:57:11Z [Term] id: GO:0061241 name: mesonephric nephron epithelium development namespace: biological_process def: "The process whose specific outcome is the progression of the mesonephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The mesonephric nephron epithelium is a tissue that covers the surface of a nephron in the mesonephros." [GOC:mtg_kidney_jan10] is_a: GO:0072009 ! nephron epithelium development is_a: GO:0072163 ! mesonephric epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005330 ! results in development of mesonephric nephron epithelium relationship: BFO:0000050 GO:0061215 ! part of mesonephric nephron development relationship: RO:0002296 UBERON:0005330 ! results in development of mesonephric nephron epithelium creation_date: 2010-08-19T03:11:59Z [Term] id: GO:0061243 name: mesonephric renal vesicle morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the mesonephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the mesonephric nephron epithelium, and is formed by the condensation of mesenchymal cells." [GOC:mtg_kidney_jan10] is_a: GO:0072077 ! renal vesicle morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0005331 ! results in morphogenesis of mesonephric renal vesicle relationship: BFO:0000050 GO:0061228 ! part of mesonephric nephron morphogenesis relationship: RO:0002298 UBERON:0005331 ! results in morphogenesis of mesonephric renal vesicle creation_date: 2010-08-19T03:20:21Z [Term] id: GO:0061261 name: mesenchymal to epithelial transition involved in mesonephros morphogenesis namespace: biological_process def: "A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephros." [GOC:mtg_kidney_jan10] is_a: GO:0035850 ! epithelial cell differentiation involved in kidney development is_a: GO:0060231 ! mesenchymal to epithelial transition is_a: GO:0061208 ! cell differentiation involved in mesonephros development intersection_of: GO:0060231 ! mesenchymal to epithelial transition intersection_of: BFO:0000050 GO:0061206 ! part of mesonephros morphogenesis relationship: BFO:0000050 GO:0061206 ! part of mesonephros morphogenesis creation_date: 2010-08-30T02:35:15Z [Term] id: GO:0061262 name: mesonephric renal vesicle formation namespace: biological_process def: "The developmental process pertaining to the initial formation of the mesonephros." [GOC:mtg_kidney_jan10] synonym: "mesonephros formation" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0072033 ! renal vesicle formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0005331 ! results in formation of anatomical entity mesonephric renal vesicle relationship: BFO:0000050 GO:0061243 ! part of mesonephric renal vesicle morphogenesis relationship: RO:0002297 UBERON:0005331 ! results in formation of anatomical entity mesonephric renal vesicle creation_date: 2010-08-30T02:41:20Z [Term] id: GO:0061271 name: mesenchymal to epithelial transition involved in mesonephric renal vesicle formation namespace: biological_process def: "A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephric renal vesicle." [GOC:mtg_kidney_jan10] is_a: GO:0061261 ! mesenchymal to epithelial transition involved in mesonephros morphogenesis is_a: GO:0072036 ! mesenchymal to epithelial transition involved in renal vesicle formation intersection_of: GO:0060231 ! mesenchymal to epithelial transition intersection_of: BFO:0000050 GO:0061262 ! part of mesonephric renal vesicle formation relationship: BFO:0000050 GO:0061262 ! part of mesonephric renal vesicle formation creation_date: 2010-08-30T03:26:30Z [Term] id: GO:0061285 name: mesonephric capsule development namespace: biological_process def: "The progression of the mesonephric capsule over time, from its formation to the mature structure. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue." [GOC:mtg_kidney_jan10] is_a: GO:0072127 ! renal capsule development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0006170 ! results in development of mesonephric capsule relationship: BFO:0000050 GO:0001823 ! part of mesonephros development relationship: RO:0002296 UBERON:0006170 ! results in development of mesonephric capsule creation_date: 2010-09-02T01:50:06Z [Term] id: GO:0061286 name: mesonephric capsule morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the mesonephric capsule are generated and organized. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage." [GOC:mtg_kidney_jan10] is_a: GO:0072128 ! renal capsule morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0006170 ! results in morphogenesis of mesonephric capsule relationship: BFO:0000050 GO:0061285 ! part of mesonephric capsule development relationship: RO:0002298 UBERON:0006170 ! results in morphogenesis of mesonephric capsule creation_date: 2010-09-02T01:53:31Z [Term] id: GO:0061287 name: mesonephric capsule formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a mesonephric capsule from unspecified parts. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage." [GOC:mtg_kidney_jan10] is_a: GO:0072129 ! renal capsule formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0006170 ! results in formation of anatomical entity mesonephric capsule relationship: BFO:0000050 GO:0061286 ! part of mesonephric capsule morphogenesis relationship: RO:0002297 UBERON:0006170 ! results in formation of anatomical entity mesonephric capsule creation_date: 2010-09-02T01:55:03Z [Term] id: GO:0061295 name: regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis namespace: biological_process def: "Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] synonym: "regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis" EXACT [] is_a: GO:0072039 ! regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1901146 ! regulates (processual) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis relationship: RO:0002211 GO:0061235 ! regulates (processual) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis relationship: RO:0002211 GO:1901146 ! regulates (processual) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis creation_date: 2010-09-06T09:48:56Z [Term] id: GO:0061296 name: negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis namespace: biological_process def: "Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] synonym: "negative regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis" EXACT [] is_a: GO:0061218 ! negative regulation of mesonephros development is_a: GO:0061295 ! regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis is_a: GO:0072040 ! negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1901146 ! negatively regulates mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis relationship: RO:0002212 GO:0061235 ! negatively regulates mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis relationship: RO:0002212 GO:1901146 ! negatively regulates mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis creation_date: 2010-09-06T09:54:49Z [Term] id: GO:0061297 name: positive regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis namespace: biological_process def: "Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] synonym: "positive regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis" EXACT [] is_a: GO:0061213 ! positive regulation of mesonephros development is_a: GO:0061295 ! regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis is_a: GO:0072041 ! positive regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1901146 ! positively regulates mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis relationship: RO:0002213 GO:0061235 ! positively regulates mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis relationship: RO:0002213 GO:1901146 ! positively regulates mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis creation_date: 2010-09-06T09:58:59Z [Term] id: GO:0061298 name: retina vasculature development in camera-type eye namespace: biological_process def: "The process whose specific outcome is the progression of the vasculature of the retina over time, from its formation to the mature structure." [GOC:BHF, GOC:dph] synonym: "retinal vasculature development" EXACT [GOC:dph] is_a: GO:0001944 ! vasculature development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004864 ! results in development of vasculature of retina relationship: BFO:0000050 GO:0060041 ! part of retina development in camera-type eye relationship: RO:0002296 UBERON:0004864 ! results in development of vasculature of retina creation_date: 2010-09-06T03:27:06Z [Term] id: GO:0061299 name: retina vasculature morphogenesis in camera-type eye namespace: biological_process def: "The process in which the vasculature of the retina is generated and organized." [GOC:BHF, GOC:dph] synonym: "retinal vasculature morphogenesis" EXACT [GOC:dph] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0004864 ! results in morphogenesis of vasculature of retina relationship: BFO:0000050 GO:0061298 ! part of retina vasculature development in camera-type eye relationship: RO:0002298 UBERON:0004864 ! results in morphogenesis of vasculature of retina creation_date: 2010-09-06T03:28:25Z [Term] id: GO:0061303 name: cornea development in camera-type eye namespace: biological_process def: "The progression of the cornea over time, from its formation to the mature structure. The cornea is the transparent structure that covers the anterior of the eye." [GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000964 ! results in development of cornea relationship: BFO:0000050 GO:0043010 ! part of camera-type eye development relationship: RO:0002296 UBERON:0000964 ! results in development of cornea creation_date: 2010-09-14T02:09:08Z [Term] id: GO:0061304 name: retinal blood vessel morphogenesis namespace: biological_process def: "The process whose specific outcome is the progression of a blood vessel of the retina over time, from its formation to the mature structure." [GOC:BHF, GOC:dph] is_a: GO:0048514 ! blood vessel morphogenesis is_a: GO:0061299 ! retina vasculature morphogenesis in camera-type eye intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003501 ! results in morphogenesis of retina blood vessel relationship: RO:0002298 UBERON:0003501 ! results in morphogenesis of retina blood vessel creation_date: 2010-09-16T09:02:59Z [Term] id: GO:0061307 name: cardiac neural crest cell differentiation involved in heart development namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a cardiac neural crest cell that will migrate to the heart and contribute to its development. Cardiac neural crest cells are specialized cells that migrate toward the heart from the third, fourth and sixth pharyngeal arches." [GOC:dph, GOC:mtg_heart, PMID:19705442] is_a: GO:0014033 ! neural crest cell differentiation is_a: GO:0035051 ! cardiocyte differentiation intersection_of: GO:0014033 ! neural crest cell differentiation intersection_of: BFO:0000050 GO:0007507 ! part of heart development creation_date: 2010-09-23T08:50:56Z [Term] id: GO:0061308 name: cardiac neural crest cell development involved in heart development namespace: biological_process def: "The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the development of the heart." [GOC:dph, GOC:mtg_heart] is_a: GO:0014032 ! neural crest cell development intersection_of: GO:0014032 ! neural crest cell development intersection_of: BFO:0000050 GO:0007507 ! part of heart development relationship: BFO:0000050 GO:0061307 ! part of cardiac neural crest cell differentiation involved in heart development creation_date: 2010-09-23T09:01:49Z [Term] id: GO:0061309 name: cardiac neural crest cell development involved in outflow tract morphogenesis namespace: biological_process def: "The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the shaping of the outflow tract." [GOC:dph, GOC:mtg_heart] is_a: GO:0061308 ! cardiac neural crest cell development involved in heart development intersection_of: GO:0014032 ! neural crest cell development intersection_of: BFO:0000050 GO:0003151 ! part of outflow tract morphogenesis relationship: BFO:0000050 GO:0003151 ! part of outflow tract morphogenesis creation_date: 2010-09-23T09:08:37Z [Term] id: GO:0061323 name: cell proliferation involved in heart morphogenesis namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the heart." [GOC:dph, GOC:mtg_heart] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: BFO:0000050 GO:0003007 ! part of heart morphogenesis relationship: BFO:0000050 GO:0003007 ! part of heart morphogenesis creation_date: 2010-09-28T09:05:26Z [Term] id: GO:0061325 name: cell proliferation involved in outflow tract morphogenesis namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the outflow tract." [GOC:dph, GOC:mtg_heart] is_a: GO:0061323 ! cell proliferation involved in heart morphogenesis intersection_of: GO:0008283 ! cell population proliferation intersection_of: BFO:0000050 GO:0003151 ! part of outflow tract morphogenesis relationship: BFO:0000050 GO:0003151 ! part of outflow tract morphogenesis creation_date: 2010-09-28T09:29:30Z [Term] id: GO:0061326 name: renal tubule development namespace: biological_process def: "The progression of the renal tubule over time from its formation to the mature form. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis." [GOC:dph, GOC:mtg_kidney_jan10] is_a: GO:0035295 ! tube development is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0009773 ! results in development of renal tubule relationship: BFO:0000050 GO:0072001 ! part of renal system development relationship: RO:0002296 UBERON:0009773 ! results in development of renal tubule creation_date: 2010-09-28T12:50:43Z [Term] id: GO:0061333 name: renal tubule morphogenesis namespace: biological_process def: "The process in which the renal tubule is generated by specification of cell fate, through the maintenance of cell polarity, regulated cell proliferation and morphogenetic cell rearrangements, shape changes and growth. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis." [GOC:dph, GOC:mtg_kidney_jan10] is_a: GO:0060562 ! epithelial tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0009773 ! results in morphogenesis of renal tubule relationship: BFO:0000050 GO:0061326 ! part of renal tubule development relationship: RO:0002298 UBERON:0009773 ! results in morphogenesis of renal tubule creation_date: 2010-09-28T01:43:04Z [Term] id: GO:0061337 name: cardiac conduction namespace: biological_process def: "Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles." [GOC:dph] is_a: GO:0008016 ! regulation of heart contraction creation_date: 2010-09-29T08:46:05Z [Term] id: GO:0061343 name: cell adhesion involved in heart morphogenesis namespace: biological_process def: "The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the shaping of the heart." [GOC:dph, GOC:mtg_heart, PMID:16860783] is_a: GO:0007155 ! cell adhesion intersection_of: GO:0007155 ! cell adhesion intersection_of: BFO:0000050 GO:0003007 ! part of heart morphogenesis relationship: BFO:0000050 GO:0003007 ! part of heart morphogenesis creation_date: 2010-09-29T11:34:06Z [Term] id: GO:0061344 name: regulation of cell adhesion involved in heart morphogenesis namespace: biological_process def: "Any process that modulates the extent of cell adhesion contributing to the shaping of the heart." [GOC:dph, GOC:mtg_heart, PMID:16860783] is_a: GO:0030155 ! regulation of cell adhesion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0061343 ! regulates (processual) cell adhesion involved in heart morphogenesis relationship: RO:0002211 GO:0061343 ! regulates (processual) cell adhesion involved in heart morphogenesis creation_date: 2010-09-29T11:35:27Z [Term] id: GO:0061351 name: neural precursor cell proliferation namespace: biological_process def: "The multiplication or reproduction of neural precursor cells, resulting in the expansion of a cell population. A neural precursor cell is either a nervous system stem cell or a nervous system progenitor cell." [GOC:dph, GOC:yaf] is_a: GO:0008283 ! cell population proliferation creation_date: 2010-10-01T11:06:04Z [Term] id: GO:0061383 name: trabecula morphogenesis namespace: biological_process def: "The process of shaping a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue." [GOC:dph] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000440 ! results in morphogenesis of trabecula relationship: RO:0002298 UBERON:0000440 ! results in morphogenesis of trabecula creation_date: 2010-12-02T08:51:45Z [Term] id: GO:0061384 name: heart trabecula morphogenesis namespace: biological_process def: "The process of shaping a trabecula in the heart. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue." [GOC:dph] is_a: GO:0061383 ! trabecula morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002511 ! results in morphogenesis of trabecula carnea relationship: RO:0002298 UBERON:0002511 ! results in morphogenesis of trabecula carnea creation_date: 2010-12-02T08:54:20Z [Term] id: GO:0061385 name: fibroblast proliferation involved in heart morphogenesis namespace: biological_process def: "The multiplication or reproduction of fibroblasts, resulting in the expansion of a fibroblast population that contributes to the shaping of the heart." [GOC:dph] is_a: GO:0048144 ! fibroblast proliferation is_a: GO:0061323 ! cell proliferation involved in heart morphogenesis intersection_of: GO:0048144 ! fibroblast proliferation intersection_of: BFO:0000050 GO:0003007 ! part of heart morphogenesis creation_date: 2011-02-10T01:41:59Z [Term] id: GO:0061437 name: renal system vasculature development namespace: biological_process def: "The process whose specific outcome is the progression of vasculature of the renal system over time, from its formation to the mature structure." [GOC:dph, GOC:mtg_kidney_jan10, PMID:11891195] is_a: GO:0001944 ! vasculature development relationship: BFO:0000050 GO:0072001 ! part of renal system development creation_date: 2012-03-08T12:16:24Z [Term] id: GO:0061438 name: renal system vasculature morphogenesis namespace: biological_process def: "The process in which the renal system vasculature is generated and organized. Morphogenesis pertains to the creation of form." [GOC:dph, GOC:mtg_kidney_jan10, PMID:11891195] is_a: GO:0009653 ! anatomical structure morphogenesis relationship: BFO:0000050 GO:0061437 ! part of renal system vasculature development creation_date: 2012-03-08T12:21:56Z [Term] id: GO:0061439 name: kidney vasculature morphogenesis namespace: biological_process def: "The process in which the kidney vasculature is generated and organized. Morphogenesis pertains to the creation of form." [GOC:dph, GOC:mtg_kidney_jan10] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0006544 ! results in morphogenesis of kidney vasculature relationship: BFO:0000050 GO:0061438 ! part of renal system vasculature morphogenesis relationship: BFO:0000050 GO:0061440 ! part of kidney vasculature development relationship: RO:0002298 UBERON:0006544 ! results in morphogenesis of kidney vasculature creation_date: 2012-03-08T12:30:11Z [Term] id: GO:0061440 name: kidney vasculature development namespace: biological_process def: "The process whose specific outcome is the progression of the vasculature of the kidney over time, from its formation to the mature structure." [GOC:dph, GOC:mtg_kidney_jan10, PMID:11891195] is_a: GO:0061437 ! renal system vasculature development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0006544 ! results in development of kidney vasculature relationship: BFO:0000050 GO:0001822 ! part of kidney development relationship: RO:0002296 UBERON:0006544 ! results in development of kidney vasculature creation_date: 2012-03-08T12:39:09Z [Term] id: GO:0061441 name: renal artery morphogenesis namespace: biological_process def: "The process in which the anatomical structure of a renal artery is generated and organized. Renal arteries supply the kidneys with blood." [GOC:mtg_kidney_jan10, PMID:11891195] is_a: GO:0048844 ! artery morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001184 ! results in morphogenesis of renal artery relationship: BFO:0000050 GO:0061439 ! part of kidney vasculature morphogenesis relationship: RO:0002298 UBERON:0001184 ! results in morphogenesis of renal artery creation_date: 2012-03-08T12:42:09Z [Term] id: GO:0061448 name: connective tissue development namespace: biological_process def: "The progression of a connective tissue over time, from its formation to the mature structure." [GOC:BHF] is_a: GO:0009888 ! tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002384 ! results in development of connective tissue relationship: RO:0002296 UBERON:0002384 ! results in development of connective tissue creation_date: 2012-03-22T12:53:41Z [Term] id: GO:0061450 name: trophoblast cell migration namespace: biological_process def: "Trophoblast cell migration that is accomplished by extension and retraction of a pseudopodium. Trophoblast cells line the outside of the blastocyst." [GOC:dph] is_a: GO:0001667 ! ameboidal-type cell migration is_a: GO:0022414 ! reproductive process intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000351 ! results in movement of trophoblast cell relationship: BFO:0000050 GO:0007566 ! part of embryo implantation relationship: RO:0002565 CL:0000351 ! results in movement of trophoblast cell creation_date: 2012-07-10T08:38:37Z [Term] id: GO:0061453 name: interstitial cell of Cajal differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of an interstitial cell of Cajal. An interstitial cell of Cajal is an intestinal neuroepithelial cell that serves as a pacemaker to trigger gut contraction." [GOC:dph] is_a: GO:0060563 ! neuroepithelial cell differentiation is_a: GO:0060575 ! intestinal epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0002088 ! results in acquisition of features of interstitial cell of Cajal relationship: RO:0002315 CL:0002088 ! results in acquisition of features of interstitial cell of Cajal creation_date: 2012-07-20T08:20:50Z [Term] id: GO:0061458 name: reproductive system development namespace: biological_process def: "The progression of the reproductive system over time from its formation to the mature structure. The reproductive system consists of the organs that function in reproduction." [GOC:dph] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000990 ! results in development of reproductive system relationship: RO:0002296 UBERON:0000990 ! results in development of reproductive system creation_date: 2012-08-22T17:47:53Z [Term] id: GO:0061469 name: regulation of type B pancreatic cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of type B pancreatic cell proliferation." [GOC:dph] is_a: GO:0050678 ! regulation of epithelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0044342 ! regulates (processual) type B pancreatic cell proliferation relationship: RO:0002211 GO:0044342 ! regulates (processual) type B pancreatic cell proliferation creation_date: 2012-11-01T13:16:23Z [Term] id: GO:0061484 name: hematopoietic stem cell homeostasis namespace: biological_process def: "Any biological process involved in the maintenance of the steady-state number of hematopoietic stem cells within a population of cells." [GOC:dph, PMID:21508411] is_a: GO:0048872 ! homeostasis of number of cells intersection_of: GO:0048872 ! homeostasis of number of cells intersection_of: RO:0012003 CL:0000037 ! acts on population of hematopoietic stem cell relationship: RO:0012003 CL:0000037 ! acts on population of hematopoietic stem cell creation_date: 2012-12-04T09:41:02Z [Term] id: GO:0061512 name: protein localization to cilium namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within a cilium." [GOC:dph] is_a: GO:0033365 ! protein localization to organelle intersection_of: GO:0008104 ! protein localization intersection_of: RO:0002339 GO:0005929 ! has target end location cilium relationship: RO:0002160 NCBITaxon:2759 ! only in taxon Eukaryota relationship: RO:0002162 NCBITaxon:2759 {all_only="true"} ! in taxon Eukaryota relationship: RO:0002339 GO:0005929 ! has target end location cilium creation_date: 2013-03-22T15:41:44Z [Term] id: GO:0061515 name: myeloid cell development namespace: biological_process def: "The process whose specific outcome is the progression of a myeloid cell over time, from its formation to the mature structure." [GOC:dph] is_a: GO:0030097 ! hemopoiesis intersection_of: GO:0048468 ! cell development intersection_of: RO:0002296 CL:0000763 ! results in development of myeloid cell relationship: BFO:0000050 GO:0030099 ! part of myeloid cell differentiation relationship: RO:0002296 CL:0000763 ! results in development of myeloid cell creation_date: 2013-04-18T13:03:16Z [Term] id: GO:0061523 name: cilium disassembly namespace: biological_process def: "A cellular process that results in the breakdown of a cilium." [GOC:cilia, GOC:dph, PMID:17604723, PMID:27350441] synonym: "cilium resorption" EXACT [GOC:dph] is_a: GO:0044782 ! cilium organization is_a: GO:1903008 ! organelle disassembly intersection_of: GO:0022411 ! cellular component disassembly intersection_of: RO:0002590 GO:0005929 ! results in disassembly of cilium relationship: RO:0002590 GO:0005929 ! results in disassembly of cilium creation_date: 2013-04-18T14:59:59Z [Term] id: GO:0061525 name: hindgut development namespace: biological_process def: "The process whose specific outcome is the progression of the hindgut over time, from its formation to the mature structure. The hindgut is part of the alimentary canal that lies posterior to the midgut." [GOC:dph] is_a: GO:0048565 ! digestive tract development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001046 ! results in development of hindgut relationship: RO:0002296 UBERON:0001046 ! results in development of hindgut creation_date: 2013-06-14T11:22:21Z [Term] id: GO:0061526 name: acetylcholine secretion namespace: biological_process def: "The regulated release of acetylcholine by a cell." [GOC:dph] is_a: GO:0015870 ! acetylcholine transport is_a: GO:0023061 ! signal release intersection_of: GO:0046903 ! secretion intersection_of: RO:0004009 CHEBI:15355 ! has primary input acetylcholine creation_date: 2013-06-21T15:40:39Z [Term] id: GO:0061533 name: norepinephrine secretion, neurotransmission namespace: biological_process def: "The regulated release of norepinephrine by a cell, in which the norepinephrine acts as a neurotransmitter." [GOC:dph] synonym: "noradrenaline secretion, neurotransmission" EXACT [GOC:dph] is_a: GO:0048243 ! norepinephrine secretion is_a: GO:0160043 ! catecholamine secretion, neurotransmission intersection_of: GO:0007269 ! neurotransmitter secretion intersection_of: RO:0004009 CHEBI:72587 ! has primary input (R)-noradrenaline(1+) creation_date: 2013-06-21T16:05:08Z [Term] id: GO:0061548 name: ganglion development namespace: biological_process def: "The process whose specific outcome is the progression of a ganglion over time, from its formation to the mature structure." [GOC:dph] is_a: GO:0009888 ! tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000045 ! results in development of ganglion relationship: BFO:0000050 GO:0007399 ! part of nervous system development relationship: RO:0002296 UBERON:0000045 ! results in development of ganglion creation_date: 2013-07-10T08:36:12Z [Term] id: GO:0061549 name: sympathetic ganglion development namespace: biological_process def: "The process whose specific outcome is the progression of a sympathetic ganglion over time, from its formation to the mature structure." [GOC:BHF, GOC:rl] is_a: GO:0061548 ! ganglion development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001806 ! results in development of sympathetic ganglion relationship: BFO:0000050 GO:0048485 ! part of sympathetic nervous system development relationship: RO:0002296 UBERON:0001806 ! results in development of sympathetic ganglion creation_date: 2013-07-10T08:38:01Z [Term] id: GO:0061550 name: cranial ganglion development namespace: biological_process def: "The process whose specific outcome is the progression of a cranial ganglion over time, from its formation to the mature structure." [GOC:dph] is_a: GO:0061548 ! ganglion development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001714 ! results in development of cranial ganglion relationship: BFO:0000050 GO:0021545 ! part of cranial nerve development relationship: RO:0002296 UBERON:0001714 ! results in development of cranial ganglion creation_date: 2013-07-10T08:40:14Z [Term] id: GO:0061551 name: trigeminal ganglion development namespace: biological_process def: "The process whose specific outcome is the progression of a trigeminal ganglion over time, from its formation to the mature structure." [GOC:dph] is_a: GO:0061550 ! cranial ganglion development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001675 ! results in development of trigeminal ganglion relationship: RO:0002296 UBERON:0001675 ! results in development of trigeminal ganglion creation_date: 2013-07-10T08:42:19Z [Term] id: GO:0061552 name: ganglion morphogenesis namespace: biological_process def: "The process in which the anatomical structures of ganglion are generated and organized." [GOC:dph] is_a: GO:0048729 ! tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000045 ! results in morphogenesis of ganglion relationship: BFO:0000050 GO:0061548 ! part of ganglion development relationship: RO:0002298 UBERON:0000045 ! results in morphogenesis of ganglion creation_date: 2013-07-10T08:44:57Z [Term] id: GO:0061553 name: ganglion maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for ganglion to attain its fully functional state." [GOC:dph] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0071695 ! anatomical structure maturation intersection_of: RO:0002299 UBERON:0000045 ! results in maturation of ganglion relationship: BFO:0000050 GO:0061548 ! part of ganglion development relationship: RO:0002299 UBERON:0000045 ! results in maturation of ganglion creation_date: 2013-07-10T08:45:59Z [Term] id: GO:0061554 name: ganglion formation namespace: biological_process def: "The process that gives rise to ganglion. This process pertains to the initial formation of a structure from unspecified parts." [GOC:dph] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0000045 ! results in formation of anatomical entity ganglion relationship: BFO:0000050 GO:0061552 ! part of ganglion morphogenesis relationship: RO:0002297 UBERON:0000045 ! results in formation of anatomical entity ganglion creation_date: 2013-07-10T08:51:50Z [Term] id: GO:0061556 name: trigeminal ganglion morphogenesis namespace: biological_process def: "The process in which the anatomical structure of a trigeminal ganglion is generated and organized." [GOC:dph] is_a: GO:0061559 ! cranial ganglion morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001675 ! results in morphogenesis of trigeminal ganglion relationship: BFO:0000050 GO:0021636 ! part of trigeminal nerve morphogenesis relationship: BFO:0000050 GO:0061551 ! part of trigeminal ganglion development relationship: RO:0002298 UBERON:0001675 ! results in morphogenesis of trigeminal ganglion creation_date: 2013-07-10T08:57:12Z [Term] id: GO:0061557 name: trigeminal ganglion maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for a trigeminal ganglion to attain its fully functional state." [GOC:dph] is_a: GO:0061558 ! cranial ganglion maturation intersection_of: GO:0071695 ! anatomical structure maturation intersection_of: RO:0002299 UBERON:0001675 ! results in maturation of trigeminal ganglion relationship: BFO:0000050 GO:0021635 ! part of trigeminal nerve maturation relationship: BFO:0000050 GO:0061551 ! part of trigeminal ganglion development relationship: RO:0002299 UBERON:0001675 ! results in maturation of trigeminal ganglion creation_date: 2013-07-10T08:58:24Z [Term] id: GO:0061558 name: cranial ganglion maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for a cranial ganglion to attain its fully functional state." [GOC:dph] is_a: GO:0061553 ! ganglion maturation intersection_of: GO:0071695 ! anatomical structure maturation intersection_of: RO:0002299 UBERON:0001714 ! results in maturation of cranial ganglion relationship: BFO:0000050 GO:0021605 ! part of cranial nerve maturation relationship: BFO:0000050 GO:0061550 ! part of cranial ganglion development relationship: RO:0002299 UBERON:0001714 ! results in maturation of cranial ganglion creation_date: 2013-07-10T08:59:52Z [Term] id: GO:0061559 name: cranial ganglion morphogenesis namespace: biological_process def: "The process in which the anatomical structure of a cranial ganglion is generated and organized." [GOC:dph] is_a: GO:0061552 ! ganglion morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001714 ! results in morphogenesis of cranial ganglion relationship: BFO:0000050 GO:0021602 ! part of cranial nerve morphogenesis relationship: BFO:0000050 GO:0061550 ! part of cranial ganglion development relationship: RO:0002298 UBERON:0001714 ! results in morphogenesis of cranial ganglion creation_date: 2013-07-10T09:02:15Z [Term] id: GO:0061560 name: cranial ganglion formation namespace: biological_process def: "The process that gives rise to a cranial ganglion. This process pertains to the initial formation of a structure from unspecified parts." [GOC:dph] is_a: GO:0061554 ! ganglion formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0001714 ! results in formation of anatomical entity cranial ganglion relationship: BFO:0000050 GO:0061559 ! part of cranial ganglion morphogenesis relationship: RO:0002297 UBERON:0001714 ! results in formation of anatomical entity cranial ganglion creation_date: 2013-07-10T09:07:27Z [Term] id: GO:0061561 name: trigeminal ganglion formation namespace: biological_process def: "The process that gives rise to the trigeminal ganglion. This process pertains to the initial formation of a structure from unspecified parts." [GOC:dph] is_a: GO:0061560 ! cranial ganglion formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0001675 ! results in formation of anatomical entity trigeminal ganglion relationship: BFO:0000050 GO:0061556 ! part of trigeminal ganglion morphogenesis relationship: RO:0002297 UBERON:0001675 ! results in formation of anatomical entity trigeminal ganglion creation_date: 2013-07-10T09:08:13Z [Term] id: GO:0061572 name: actin filament bundle organization namespace: biological_process def: "A process that results in the assembly, arrangement of constituent parts, or disassembly of an actin filament bundle." [GOC:dph] is_a: GO:0007015 ! actin filament organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0032432 ! results in organization of actin filament bundle relationship: RO:0002592 GO:0032432 ! results in organization of actin filament bundle creation_date: 2013-08-02T11:24:11Z [Term] id: GO:0061580 name: colon epithelial cell migration namespace: biological_process def: "The orderly movement of a colonic epithelial cell from one site to another, often during the development of a multicellular organism." [GOC:dph] is_a: GO:0061582 ! intestinal epithelial cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0011108 ! results in movement of colon epithelial cell relationship: RO:0002565 CL:0011108 ! results in movement of colon epithelial cell creation_date: 2013-12-23T07:26:54Z [Term] id: GO:0061581 name: corneal epithelial cell migration namespace: biological_process def: "The orderly movement of a corneal epithelial cell from one site to another, often during the development of a multicellular organism." [GOC:dph] is_a: GO:0010631 ! epithelial cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000575 ! results in movement of corneal epithelial cell relationship: RO:0002565 CL:0000575 ! results in movement of corneal epithelial cell creation_date: 2013-12-23T07:28:29Z [Term] id: GO:0061582 name: intestinal epithelial cell migration namespace: biological_process def: "The orderly movement of an intestinal epithelial cell from one site to another, often during the development of a multicellular organism." [GOC:dph] is_a: GO:0010631 ! epithelial cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0002563 ! results in movement of intestinal epithelial cell relationship: RO:0002565 CL:0002563 ! results in movement of intestinal epithelial cell creation_date: 2013-12-23T07:30:55Z [Term] id: GO:0061626 name: pharyngeal arch artery morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a pharyngeal arch artery is generated and organized. The pharyngeal arch arteries are a series of six paired embryological vascular structures, the development of which give rise to several major arteries, such as the stapedial artery, the middle meningeal artery, the internal carotid artery and the pulmonary artery." [GOC:BHF, GOC:dph, PMID:20122914] is_a: GO:0048844 ! artery morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0004363 ! results in morphogenesis of pharyngeal arch artery relationship: BFO:0000050 GO:0060037 ! part of pharyngeal system development relationship: RO:0002298 UBERON:0004363 ! results in morphogenesis of pharyngeal arch artery creation_date: 2014-05-09T15:34:06Z [Term] id: GO:0061682 name: seminal vesicle morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a seminal vesicle are generated and organized." [GOC:dph] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0022612 ! gland morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000998 ! results in morphogenesis of seminal vesicle relationship: BFO:0000050 GO:0061107 ! part of seminal vesicle development relationship: RO:0002298 UBERON:0000998 ! results in morphogenesis of seminal vesicle creation_date: 2015-03-04T13:33:49Z [Term] id: GO:0061683 name: branching involved in seminal vesicle morphogenesis namespace: biological_process def: "The process in which the branching structure of the seminal vesicle is generated and organized. A branch is a division or offshoot from a main stem." [GOC:dph, PMID:16916376] synonym: "gonecyst branching morphogenesis" EXACT [GOC:dph] synonym: "seminal gland branching morphogenesis" EXACT [GOC:dph] synonym: "seminal vesicle branching" EXACT [GOC:dph] synonym: "seminal vesicle branching morphogenesis" EXACT [GOC:dph] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0061138 ! morphogenesis of a branching epithelium intersection_of: GO:0061138 ! morphogenesis of a branching epithelium intersection_of: BFO:0000050 GO:0061682 ! part of seminal vesicle morphogenesis relationship: BFO:0000050 GO:0061108 ! part of seminal vesicle epithelium development relationship: BFO:0000050 GO:0061682 ! part of seminal vesicle morphogenesis creation_date: 2015-03-04T13:39:47Z [Term] id: GO:0061687 name: detoxification of inorganic compound namespace: biological_process def: "Any process that reduces or removes the toxicity of inorganic compounds. These include transport of such compounds away from sensitive areas and to compartments or complexes whose purpose is sequestration of inorganic compounds." [GOC:vw] is_a: GO:0098754 ! detoxification intersection_of: GO:0098754 ! detoxification intersection_of: RO:0004009 CHEBI:24835 ! has primary input inorganic molecular entity relationship: RO:0004009 CHEBI:24835 ! has primary input inorganic molecular entity creation_date: 2015-03-09T09:16:23Z [Term] id: GO:0061695 name: transferase complex, transferring phosphorus-containing groups namespace: cellular_component def: "A transferase complex capable of catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor)." [GOC:bhm, GOC:dph] is_a: GO:1990234 ! transferase complex intersection_of: GO:0032991 ! protein-containing complex intersection_of: RO:0002215 GO:0016772 ! capable of transferase activity, transferring phosphorus-containing groups relationship: RO:0002215 GO:0016772 ! capable of transferase activity, transferring phosphorus-containing groups creation_date: 2015-05-06T11:22:38Z [Term] id: GO:0061792 name: secretory granule maturation namespace: biological_process def: "Steps required to transform an immature secretory vesicle into a mature secretory vesicle. Typically proceeds through homotypic membrane fusion and membrane remodeling." [GOC:bf, GOC:dph, GOC:PARL, PMID:16618809] is_a: GO:0033363 ! secretory granule organization is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 GO:0030141 ! results in maturation of secretory granule relationship: RO:0002299 GO:0030141 ! results in maturation of secretory granule creation_date: 2016-09-09T13:24:34Z [Term] id: GO:0061853 name: regulation of neuroblast migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of neuroblast migration." [PMID:23149556] is_a: GO:0030334 ! regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0097402 ! regulates (processual) neuroblast migration relationship: RO:0002211 GO:0097402 ! regulates (processual) neuroblast migration creation_date: 2017-03-08T18:17:07Z [Term] id: GO:0061854 name: positive regulation of neuroblast migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of neuroblast migration." [PMID:23149556] is_a: GO:0030335 ! positive regulation of cell migration is_a: GO:0061853 ! regulation of neuroblast migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0097402 ! positively regulates neuroblast migration relationship: RO:0002213 GO:0097402 ! positively regulates neuroblast migration creation_date: 2017-03-08T18:22:30Z [Term] id: GO:0061855 name: negative regulation of neuroblast migration namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of neuroblast migration." [PMID:23149556] is_a: GO:0030336 ! negative regulation of cell migration is_a: GO:0061853 ! regulation of neuroblast migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0097402 ! negatively regulates neuroblast migration relationship: RO:0002212 GO:0097402 ! negatively regulates neuroblast migration creation_date: 2017-03-08T18:26:21Z [Term] id: GO:0061900 name: glial cell activation namespace: biological_process def: "A change in morphology and behavior of a glial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor." [GOC:aruk, GOC:bc, PMID:18723082] is_a: GO:0001775 ! cell activation intersection_of: GO:0001775 ! cell activation intersection_of: RO:0004009 CL:0000125 ! has primary input glial cell relationship: BFO:0000050 GO:0150076 ! part of neuroinflammatory response relationship: RO:0004009 CL:0000125 ! has primary input glial cell creation_date: 2017-06-13T13:06:23Z [Term] id: GO:0061938 name: protein localization to somatodendritic compartment namespace: biological_process def: "A process in which a protein is transported to or maintained in a location within the somatodendritic compartment." [PMID:18341993] synonym: "somatodendritic protein localization" EXACT [] is_a: GO:0008104 ! protein localization intersection_of: GO:0008104 ! protein localization intersection_of: RO:0002339 GO:0036477 ! has target end location somatodendritic compartment relationship: RO:0002339 GO:0036477 ! has target end location somatodendritic compartment creation_date: 2017-09-08T13:22:26Z [Term] id: GO:0061951 name: establishment of protein localization to plasma membrane namespace: biological_process def: "The directed movement of a protein to a specific location in a plasma membrane." [GOC:dph, GOC:vw] is_a: GO:0090150 ! establishment of protein localization to membrane intersection_of: GO:0045184 ! establishment of protein localization intersection_of: RO:0002338 GO:0005622 ! has target start location intracellular anatomical structure intersection_of: RO:0002339 GO:0005886 ! has target end location plasma membrane relationship: RO:0002338 GO:0005622 ! has target start location intracellular anatomical structure relationship: RO:0002339 GO:0005886 ! has target end location plasma membrane creation_date: 2017-10-26T12:55:15Z [Term] id: GO:0061971 name: replacement bone morphogenesis namespace: biological_process def: "The process in which bones are generated and organized as a result of the conversion of another structural tissue into bone." [PMID:29852585] is_a: GO:0060349 ! bone morphogenesis intersection_of: GO:0060349 ! bone morphogenesis intersection_of: RO:0002298 UBERON:0012075 ! results in morphogenesis of replacement bone relationship: RO:0002298 UBERON:0012075 ! results in morphogenesis of replacement bone creation_date: 2018-02-12T18:10:59Z [Term] id: GO:0061972 name: dermal bone morphogenesis namespace: biological_process def: "The process in which bone which forms superficially in the organism are generated and organized." [PMID:12588850, PMID:15003632] is_a: GO:0061973 ! membrane bone morphogenesis intersection_of: GO:0060349 ! bone morphogenesis intersection_of: RO:0002298 UBERON:0008907 ! results in morphogenesis of dermal bone relationship: RO:0002298 UBERON:0008907 ! results in morphogenesis of dermal bone creation_date: 2018-02-12T18:16:21Z [Term] id: GO:0061973 name: membrane bone morphogenesis namespace: biological_process def: "The process in which bone which forms deep in the organism are generated and organized." [PMID:14579374] is_a: GO:0060349 ! bone morphogenesis intersection_of: GO:0060349 ! bone morphogenesis intersection_of: RO:0002298 UBERON:0007842 ! results in morphogenesis of membrane bone relationship: RO:0002298 UBERON:0007842 ! results in morphogenesis of membrane bone creation_date: 2018-02-12T18:21:09Z [Term] id: GO:0061983 name: meiosis II cell cycle process namespace: biological_process def: "A process that coontributes to the second meiotic division. The second meiotic division separates chromatids resulting in a haploid number of chromosomes." [PMID:29385397] synonym: "second meiotic division" EXACT [PMID:29385397] is_a: GO:1903046 ! meiotic cell cycle process creation_date: 2018-02-14T22:37:44Z [Term] id: GO:0062012 name: regulation of small molecule metabolic process namespace: biological_process def: "Any process that modulates the rate, frequency or extent of a small molecule metabolic process." [GOC:vw] synonym: "regulation of small molecule metabolism" EXACT [] is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0044281 ! regulates (processual) small molecule metabolic process relationship: RO:0002211 GO:0044281 ! regulates (processual) small molecule metabolic process creation_date: 2018-03-19T14:11:54Z [Term] id: GO:0062013 name: positive regulation of small molecule metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of a small molecule metabolic process." [GOC:vw] synonym: "positive regulation of small molecule metabolism" EXACT [] is_a: GO:0009893 ! positive regulation of metabolic process is_a: GO:0062012 ! regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0044281 ! positively regulates small molecule metabolic process relationship: RO:0002213 GO:0044281 ! positively regulates small molecule metabolic process creation_date: 2018-03-19T14:25:10Z [Term] id: GO:0062014 name: negative regulation of small molecule metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of a small molecule metabolic process." [GOC:vw] synonym: "negative regulation of small molecule metabolism" EXACT [] is_a: GO:0009892 ! negative regulation of metabolic process is_a: GO:0062012 ! regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0044281 ! negatively regulates small molecule metabolic process relationship: RO:0002212 GO:0044281 ! negatively regulates small molecule metabolic process creation_date: 2018-03-19T14:27:23Z [Term] id: GO:0062023 name: collagen-containing extracellular matrix namespace: cellular_component def: "An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells." [GOC:BHF, GOC:rph, PMID:21123617] is_a: GO:0031012 ! extracellular matrix relationship: RO:0002160 NCBITaxon:33208 ! only in taxon Metazoa relationship: RO:0002162 NCBITaxon:33208 {all_only="true"} ! in taxon Metazoa creation_date: 2018-04-13T12:47:21Z [Term] id: GO:0062033 name: positive regulation of mitotic sister chromatid segregation namespace: biological_process def: "Any process that starts or increases the frequency, rate or extent of sister chromatid segregation during mitosis." [PMID:12773390] is_a: GO:0033047 ! regulation of mitotic sister chromatid segregation is_a: GO:0051984 ! positive regulation of chromosome segregation is_a: GO:2001252 ! positive regulation of chromosome organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0000070 ! positively regulates mitotic sister chromatid segregation relationship: RO:0002213 GO:0000070 ! positively regulates mitotic sister chromatid segregation creation_date: 2018-04-23T14:32:23Z [Term] id: GO:0062094 name: stomach development namespace: biological_process def: "The process whose specific outcome is the progression of the stomach over time, from its formation to the mature structure. The stomach is an expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ." [PMID:11967278] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000945 ! results in development of stomach relationship: BFO:0000050 GO:0048565 ! part of digestive tract development relationship: RO:0002296 UBERON:0000945 ! results in development of stomach creation_date: 2018-11-20T18:15:45Z [Term] id: GO:0062149 name: detection of stimulus involved in sensory perception of pain namespace: biological_process def: "The series of events involved in the perception of pain in which a stimulus is received and converted into a molecular signal." [PMID:19837031] is_a: GO:0050906 ! detection of stimulus involved in sensory perception intersection_of: GO:0051606 ! detection of stimulus intersection_of: BFO:0000050 GO:0019233 ! part of sensory perception of pain relationship: BFO:0000050 GO:0019233 ! part of sensory perception of pain creation_date: 2019-09-13T13:48:47Z [Term] id: GO:0062223 name: regulation of somatic muscle development namespace: biological_process def: "Any process that regulates the rate, frequency or extent of somatic muscle development." [PMID:16643882, PMID:25758712] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007525 ! regulates (processual) somatic muscle development relationship: RO:0002211 GO:0007525 ! regulates (processual) somatic muscle development creation_date: 2020-03-13T18:58:37Z [Term] id: GO:0062224 name: positive regulation of somatic muscle development namespace: biological_process def: "Any process that increases the rate, frequency or extent of somatic muscle development." [PMID:16643882, PMID:25758712] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0062223 ! regulation of somatic muscle development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007525 ! positively regulates somatic muscle development relationship: RO:0002213 GO:0007525 ! positively regulates somatic muscle development creation_date: 2020-03-13T19:03:38Z [Term] id: GO:0062225 name: negative regulation of somatic muscle development namespace: biological_process def: "Any process that decreases the rate, frequency or extent of somatic muscle development." [PMID:16643882, PMID:25758712] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0062223 ! regulation of somatic muscle development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007525 ! negatively regulates somatic muscle development relationship: RO:0002212 GO:0007525 ! negatively regulates somatic muscle development creation_date: 2020-03-13T19:06:27Z [Term] id: GO:0062237 name: protein localization to postsynapse namespace: biological_process def: "Any process in which a protein is transported to, and/or maintained at the postsynapse, the part of a synapse that is part of the post-synaptic cell." [PMID:31189538] is_a: GO:0035418 ! protein localization to synapse intersection_of: GO:0008104 ! protein localization intersection_of: RO:0002339 GO:0098794 ! has target end location postsynapse relationship: RO:0002339 GO:0098794 ! has target end location postsynapse creation_date: 2020-04-20T13:58:43Z [Term] id: GO:0065002 name: intracellular protein transmembrane transport namespace: biological_process def: "The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore." [GOC:isa_complete] synonym: "intracellular membrane translocation of a protein" EXACT [] synonym: "intracellular protein membrane transport" EXACT [] synonym: "intracellular protein transport across a membrane" EXACT [] is_a: GO:0006886 ! intracellular protein transport is_a: GO:0071806 ! protein transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: BFO:0000066 GO:0005622 ! occurs in intracellular anatomical structure intersection_of: RO:0002342 GO:0016020 ! results in transport across membrane intersection_of: RO:0004009 PR:000000001 ! has primary input protein [Term] id: GO:0065003 name: protein-containing complex assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex." [GOC:jl] synonym: "cellular protein complex assembly" EXACT [] is_a: GO:0022607 ! cellular component assembly is_a: GO:0043933 ! protein-containing complex organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0032991 ! results in assembly of protein-containing complex relationship: RO:0002588 GO:0032991 ! results in assembly of protein-containing complex [Term] id: GO:0065004 name: protein-DNA complex assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex." [GOC:jl] synonym: "DNA-protein complex assembly" EXACT [GOC:mah] is_a: GO:0065003 ! protein-containing complex assembly is_a: GO:0071824 ! protein-DNA complex organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0032993 ! results in assembly of protein-DNA complex relationship: RO:0002588 GO:0032993 ! results in assembly of protein-DNA complex [Term] id: GO:0065007 name: biological regulation namespace: biological_process def: "Any process that modulates a measurable attribute of any biological process, quality or function." [GOC:dph, GOC:isa_complete, GOC:mah, GOC:pr, GOC:vw] is_a: GO:0008150 ! biological_process [Term] id: GO:0065008 name: regulation of biological quality namespace: biological_process def: "Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc." [GOC:dph, GOC:isa_complete, GOC:mah, GOC:pr, GOC:vw] synonym: "regulation of biological attribute" EXACT [] synonym: "regulation of biological characteristic" EXACT [] is_a: GO:0065007 ! biological regulation [Term] id: GO:0065009 name: regulation of molecular function namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding." [GOC:isa_complete] synonym: "regulation of a molecular function" EXACT [] is_a: GO:0065007 ! biological regulation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003674 ! regulates (processual) molecular_function relationship: RO:0002211 GO:0003674 ! regulates (processual) molecular_function [Term] id: GO:0065010 name: extracellular membrane-bounded organelle namespace: cellular_component def: "Organized structure of distinctive morphology and function, bounded by a lipid bilayer membrane and occurring outside the cell." [GOC:isa_complete] synonym: "extracellular membrane-enclosed organelle" EXACT [] is_a: GO:0043227 ! membrane-bounded organelle is_a: GO:0043230 ! extracellular organelle intersection_of: GO:0043227 ! membrane-bounded organelle intersection_of: BFO:0000050 GO:0005576 ! part of extracellular region [Term] id: GO:0070013 name: intracellular organelle lumen namespace: cellular_component def: "An organelle lumen that is part of an intracellular organelle." [GOC:mah] is_a: GO:0043233 ! organelle lumen intersection_of: GO:0031974 ! membrane-enclosed lumen intersection_of: BFO:0000050 GO:0043229 ! part of intracellular organelle relationship: BFO:0000050 GO:0043229 ! part of intracellular organelle [Term] id: GO:0070050 name: neuron cellular homeostasis namespace: biological_process def: "The cellular homeostatic process that preserves a neuron in a stable, differentiated functional and structural state." [GOC:BHF, GOC:mah] synonym: "neuron maintenance" EXACT [] is_a: GO:0019725 ! cellular homeostasis intersection_of: GO:0019725 ! cellular homeostasis intersection_of: BFO:0000066 CL:0000540 ! occurs in neuron relationship: BFO:0000066 CL:0000540 ! occurs in neuron [Term] id: GO:0070062 name: extracellular exosome namespace: cellular_component def: "A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm." [GOC:BHF, GOC:mah, GOC:vesicles, PMID:15908444, PMID:17641064, PMID:19442504, PMID:19498381, PMID:22418571, PMID:24009894] synonym: "exosome" EXACT [GOC:pr] synonym: "extracellular vesicular exosome" EXACT [GOC:vesicles] is_a: GO:1903561 ! extracellular vesicle relationship: BFO:0000050 GO:0005615 ! part of extracellular space [Term] id: GO:0070091 name: glucagon secretion namespace: biological_process def: "The regulated release of glucagon from secretory granules in the A (alpha) cells of the pancreas (islets of Langerhans)." [GOC:BHF, GOC:rl] is_a: GO:0030072 ! peptide hormone secretion intersection_of: GO:0046903 ! secretion intersection_of: RO:0004009 CHEBI:5391 ! has primary input glucagon relationship: RO:0004009 CHEBI:5391 ! has primary input glucagon [Term] id: GO:0070092 name: regulation of glucagon secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of glucagon." [GOC:BHF, GOC:mah] is_a: GO:0090276 ! regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0070091 ! regulates (processual) glucagon secretion relationship: RO:0002211 GO:0070091 ! regulates (processual) glucagon secretion [Term] id: GO:0070093 name: negative regulation of glucagon secretion namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of glucagon." [GOC:BHF, GOC:mah] synonym: "down regulation of glucagon secretion" EXACT [] synonym: "down-regulation of glucagon secretion" EXACT [] synonym: "downregulation of glucagon secretion" EXACT [] is_a: GO:0070092 ! regulation of glucagon secretion is_a: GO:0090278 ! negative regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0070091 ! negatively regulates glucagon secretion relationship: RO:0002212 GO:0070091 ! negatively regulates glucagon secretion [Term] id: GO:0070094 name: positive regulation of glucagon secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of glucagon." [GOC:BHF, GOC:mah] synonym: "up regulation of glucagon secretion" EXACT [] synonym: "up-regulation of glucagon secretion" EXACT [] synonym: "upregulation of glucagon secretion" EXACT [] is_a: GO:0070092 ! regulation of glucagon secretion is_a: GO:0090277 ! positive regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0070091 ! positively regulates glucagon secretion relationship: RO:0002213 GO:0070091 ! positively regulates glucagon secretion [Term] id: GO:0070161 name: anchoring junction namespace: cellular_component def: "A cell junction that mechanically attaches a cell (and its cytoskeleton) to neighboring cells or to the extracellular matrix." [ISBN:0815332181] synonym: "anchoring cell junction" EXACT [GOC:mah] is_a: GO:0030054 ! cell junction [Term] id: GO:0070192 name: chromosome organization involved in meiotic cell cycle namespace: biological_process def: "A process of chromosome organization that is involved in a meiotic cell cycle." [GOC:mah] synonym: "chromosome organisation involved in meiosis" EXACT [GOC:mah] synonym: "meiotic chromosome organization" EXACT [GOC:mah] is_a: GO:0051276 ! chromosome organization is_a: GO:1903046 ! meiotic cell cycle process intersection_of: GO:0051276 ! chromosome organization intersection_of: BFO:0000050 GO:0051321 ! part of meiotic cell cycle [Term] id: GO:0070199 name: establishment of protein localization to chromosome namespace: biological_process def: "The directed movement of a protein to a specific location on a chromosome." [GOC:BHF, GOC:mah] synonym: "establishment of protein localisation to chromosome" EXACT [GOC:mah] is_a: GO:0072594 ! establishment of protein localization to organelle intersection_of: GO:0045184 ! establishment of protein localization intersection_of: RO:0002339 GO:0005694 ! has target end location chromosome relationship: RO:0002339 GO:0005694 ! has target end location chromosome [Term] id: GO:0070201 name: regulation of establishment of protein localization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location." [GOC:BHF, GOC:mah] synonym: "regulation of establishment of protein localisation" EXACT [GOC:mah] is_a: GO:0032880 ! regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0045184 ! regulates (processual) establishment of protein localization relationship: RO:0002211 GO:0045184 ! regulates (processual) establishment of protein localization [Term] id: GO:0070202 name: regulation of establishment of protein localization to chromosome namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location on a chromosome." [GOC:BHF, GOC:mah] synonym: "regulation of establishment of protein localisation to chromosome" EXACT [GOC:mah] is_a: GO:0070201 ! regulation of establishment of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0070199 ! regulates (processual) establishment of protein localization to chromosome relationship: RO:0002211 GO:0070199 ! regulates (processual) establishment of protein localization to chromosome [Term] id: GO:0070227 name: lymphocyte apoptotic process namespace: biological_process def: "Any apoptotic process in a lymphocyte, a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin." [CL:0000542, GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] is_a: GO:0071887 ! leukocyte apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000542 ! occurs in lymphocyte relationship: BFO:0000066 CL:0000542 ! occurs in lymphocyte [Term] id: GO:0070228 name: regulation of lymphocyte apoptotic process namespace: biological_process def: "Any process that modulates the occurrence or rate of lymphocyte death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] is_a: GO:2000106 ! regulation of leukocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0070227 ! regulates (processual) lymphocyte apoptotic process relationship: RO:0002211 GO:0070227 ! regulates (processual) lymphocyte apoptotic process [Term] id: GO:0070229 name: negative regulation of lymphocyte apoptotic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] synonym: "down regulation of lymphocyte apoptosis" EXACT [GOC:add] synonym: "down-regulation of lymphocyte apoptosis" EXACT [GOC:add] synonym: "downregulation of lymphocyte apoptosis" EXACT [GOC:add] is_a: GO:0070228 ! regulation of lymphocyte apoptotic process is_a: GO:2000107 ! negative regulation of leukocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0070227 ! negatively regulates lymphocyte apoptotic process relationship: RO:0002212 GO:0070227 ! negatively regulates lymphocyte apoptotic process [Term] id: GO:0070230 name: positive regulation of lymphocyte apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of lymphocyte death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] synonym: "up regulation of lymphocyte apoptosis" EXACT [GOC:add] synonym: "up-regulation of lymphocyte apoptosis" EXACT [GOC:add] synonym: "upregulation of lymphocyte apoptosis" EXACT [GOC:add] is_a: GO:0070228 ! regulation of lymphocyte apoptotic process is_a: GO:2000108 ! positive regulation of leukocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0070227 ! positively regulates lymphocyte apoptotic process relationship: RO:0002213 GO:0070227 ! positively regulates lymphocyte apoptotic process [Term] id: GO:0070231 name: T cell apoptotic process namespace: biological_process def: "Any apoptotic process in a T cell, a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex." [CL:0000084, GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] synonym: "programmed cell death of T cells by apoptosis" EXACT [GOC:add] synonym: "T lymphocyte apoptosis" EXACT [GOC:add] synonym: "T-cell apoptosis" EXACT [GOC:add] synonym: "T-lymphocyte apoptosis" EXACT [GOC:add] is_a: GO:0070227 ! lymphocyte apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000084 ! occurs in T cell relationship: BFO:0000066 CL:0000084 ! occurs in T cell [Term] id: GO:0070232 name: regulation of T cell apoptotic process namespace: biological_process def: "Any process that modulates the occurrence or rate of T cell death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] synonym: "regulation of programmed cell death of T cells by apoptosis" EXACT [GOC:add] synonym: "regulation of T lymphocyte apoptosis" EXACT [GOC:add] synonym: "regulation of T-cell apoptosis" EXACT [GOC:add] synonym: "regulation of T-lymphocyte apoptosis" EXACT [GOC:add] is_a: GO:0070228 ! regulation of lymphocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0070231 ! regulates (processual) T cell apoptotic process relationship: RO:0002211 GO:0070231 ! regulates (processual) T cell apoptotic process [Term] id: GO:0070233 name: negative regulation of T cell apoptotic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of T cell death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] synonym: "down regulation of T cell apoptosis" EXACT [GOC:add] synonym: "down-regulation of T cell apoptosis" EXACT [GOC:add] synonym: "downregulation of T cell apoptosis" EXACT [GOC:add] synonym: "negative regulation of programmed cell death of T cells by apoptosis" EXACT [GOC:add] synonym: "negative regulation of T lymphocyte apoptosis" EXACT [GOC:add] synonym: "negative regulation of T-cell apoptosis" EXACT [GOC:add] synonym: "negative regulation of T-lymphocyte apoptosis" EXACT [GOC:add] is_a: GO:0070229 ! negative regulation of lymphocyte apoptotic process is_a: GO:0070232 ! regulation of T cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0070231 ! negatively regulates T cell apoptotic process relationship: RO:0002212 GO:0070231 ! negatively regulates T cell apoptotic process [Term] id: GO:0070234 name: positive regulation of T cell apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of T cell death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] synonym: "positive regulation of programmed cell death of T cells by apoptosis" EXACT [GOC:add] synonym: "positive regulation of T lymphocyte apoptosis" EXACT [GOC:add] synonym: "positive regulation of T-cell apoptosis" EXACT [GOC:add] synonym: "positive regulation of T-lymphocyte apoptosis" EXACT [GOC:add] synonym: "up regulation of T cell apoptosis" EXACT [GOC:add] synonym: "up-regulation of T cell apoptosis" EXACT [GOC:add] synonym: "upregulation of T cell apoptosis" EXACT [GOC:add] is_a: GO:0070230 ! positive regulation of lymphocyte apoptotic process is_a: GO:0070232 ! regulation of T cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0070231 ! positively regulates T cell apoptotic process relationship: RO:0002213 GO:0070231 ! positively regulates T cell apoptotic process [Term] id: GO:0070253 name: somatostatin secretion namespace: biological_process def: "The regulated release of somatostatin from secretory granules in the D cells of the pancreas." [GOC:mah] is_a: GO:0030072 ! peptide hormone secretion intersection_of: GO:0046903 ! secretion intersection_of: RO:0004009 CHEBI:64628 ! has primary input somatostatin relationship: RO:0004009 CHEBI:64628 ! has primary input somatostatin [Term] id: GO:0070254 name: mucus secretion namespace: biological_process def: "The regulated release of mucus by the mucosa. Mucus is a viscous slimy secretion consisting of mucins and various inorganic salts dissolved in water, with suspended epithelial cells and leukocytes. The mucosa, or mucous membrane, is the membrane covered with epithelium that lines the tubular organs of the body. Mucins are carbohydrate-rich glycoproteins that have a lubricating and protective function." [GOC:add, ISBN:068340007X, ISBN:0721662544] synonym: "mucus production" EXACT [GOC:add] is_a: GO:0007589 ! body fluid secretion is_a: GO:0032941 ! secretion by tissue intersection_of: GO:0046903 ! secretion intersection_of: RO:0004009 UBERON:0000912 ! has primary input mucus relationship: RO:0004009 UBERON:0000912 ! has primary input mucus [Term] id: GO:0070255 name: regulation of mucus secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of mucus from a cell or a tissue." [GOC:add] synonym: "regulation of mucus production" EXACT [GOC:add] is_a: GO:0050878 ! regulation of body fluid levels is_a: GO:0051046 ! regulation of secretion is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0070254 ! regulates (processual) mucus secretion relationship: RO:0002211 GO:0070254 ! regulates (processual) mucus secretion [Term] id: GO:0070256 name: negative regulation of mucus secretion namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of mucus from a cell or a tissue." [GOC:add] synonym: "negative regulation of mucus production" EXACT [GOC:add] is_a: GO:0051048 ! negative regulation of secretion is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:0070255 ! regulation of mucus secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0070254 ! negatively regulates mucus secretion relationship: RO:0002212 GO:0070254 ! negatively regulates mucus secretion [Term] id: GO:0070257 name: positive regulation of mucus secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of mucus from a cell or a tissue." [GOC:add] synonym: "positive regulation of mucus production" EXACT [GOC:add] is_a: GO:0051047 ! positive regulation of secretion is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:0070255 ! regulation of mucus secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0070254 ! positively regulates mucus secretion relationship: RO:0002213 GO:0070254 ! positively regulates mucus secretion [Term] id: GO:0070285 name: pigment cell development namespace: biological_process def: "The process whose specific outcome is the progression of a pigment cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a pigment cell fate." [GOC:cvs] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000147 ! results in development of pigment cell relationship: BFO:0000050 GO:0050931 ! part of pigment cell differentiation relationship: RO:0002296 CL:0000147 ! results in development of pigment cell [Term] id: GO:0070341 name: fat cell proliferation namespace: biological_process def: "The multiplication or reproduction of fat cells by cell division, resulting in the expansion of their population. A fat cell is an animal connective tissue cell specialized for the synthesis and storage of fat." [GOC:mah, GOC:sl] synonym: "adipocyte proliferation" EXACT [GOC:sl] synonym: "adipose cell proliferation" EXACT [GOC:sl] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000136 ! acts on population of adipocyte relationship: RO:0012003 CL:0000136 ! acts on population of adipocyte [Term] id: GO:0070344 name: regulation of fat cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of fat cell proliferation." [GOC:mah, GOC:sl] synonym: "regulation of adipocyte proliferation" EXACT [GOC:sl] synonym: "regulation of adipose cell proliferation" EXACT [GOC:sl] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0070341 ! regulates (processual) fat cell proliferation relationship: RO:0002211 GO:0070341 ! regulates (processual) fat cell proliferation [Term] id: GO:0070345 name: negative regulation of fat cell proliferation namespace: biological_process def: "Any process that stops or decreases the rate or extent of fat cell proliferation." [GOC:mah, GOC:sl] synonym: "down regulation of fat cell proliferation" EXACT [GOC:mah] synonym: "down-regulation of fat cell proliferation" EXACT [GOC:mah] synonym: "downregulation of fat cell proliferation" EXACT [GOC:mah] synonym: "negative regulation of adipocyte proliferation" EXACT [GOC:sl] synonym: "negative regulation of adipose cell proliferation" EXACT [GOC:sl] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0070344 ! regulation of fat cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0070341 ! negatively regulates fat cell proliferation relationship: RO:0002212 GO:0070341 ! negatively regulates fat cell proliferation [Term] id: GO:0070346 name: positive regulation of fat cell proliferation namespace: biological_process def: "Any process that activates or increases the rate or extent of fat cell proliferation." [GOC:mah, GOC:sl] synonym: "positive regulation of adipocyte proliferation" EXACT [GOC:sl] synonym: "positive regulation of adipose cell proliferation" EXACT [GOC:sl] synonym: "up regulation of fat cell proliferation" EXACT [GOC:mah] synonym: "up-regulation of fat cell proliferation" EXACT [GOC:mah] synonym: "upregulation of fat cell proliferation" EXACT [GOC:mah] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0070344 ! regulation of fat cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0070341 ! positively regulates fat cell proliferation relationship: RO:0002213 GO:0070341 ! positively regulates fat cell proliferation [Term] id: GO:0070365 name: hepatocyte differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized features of a hepatocyte. A hepatocyte is specialized epithelial cell that is organized into interconnected plates called lobules, and is the main structural component of the liver." [CL:0000182, PMID:7588884] synonym: "liver cell differentiation" EXACT [GOC:mah] is_a: GO:0030855 ! epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000182 ! results in acquisition of features of hepatocyte relationship: BFO:0000050 GO:0001889 ! part of liver development relationship: RO:0002315 CL:0000182 ! results in acquisition of features of hepatocyte [Term] id: GO:0070366 name: regulation of hepatocyte differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of hepatocyte differentiation." [GOC:mah, GOC:sl] synonym: "regulation of liver cell differentiation" EXACT [GOC:sl] is_a: GO:0030856 ! regulation of epithelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0070365 ! regulates (processual) hepatocyte differentiation relationship: RO:0002211 GO:0070365 ! regulates (processual) hepatocyte differentiation [Term] id: GO:0070367 name: negative regulation of hepatocyte differentiation namespace: biological_process def: "Any process that stops or decreases the rate or extent of hepatocyte differentiation." [GOC:mah, GOC:sl] synonym: "down regulation of hepatocyte differentiation" EXACT [GOC:mah] synonym: "down-regulation of hepatocyte differentiation" EXACT [GOC:mah] synonym: "downregulation of hepatocyte differentiation" EXACT [GOC:mah] synonym: "negative regulation of liver cell differentiation" EXACT [GOC:sl] is_a: GO:0030857 ! negative regulation of epithelial cell differentiation is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:0070366 ! regulation of hepatocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0070365 ! negatively regulates hepatocyte differentiation relationship: RO:0002212 GO:0070365 ! negatively regulates hepatocyte differentiation [Term] id: GO:0070368 name: positive regulation of hepatocyte differentiation namespace: biological_process def: "Any process that activates or increases the rate or extent of hepatocyte differentiation." [GOC:mah, GOC:sl] synonym: "positive regulation of liver cell differentiation" EXACT [GOC:sl] synonym: "up regulation of hepatocyte differentiation" EXACT [GOC:mah] synonym: "up-regulation of hepatocyte differentiation" EXACT [GOC:mah] synonym: "upregulation of hepatocyte differentiation" EXACT [GOC:mah] is_a: GO:0030858 ! positive regulation of epithelial cell differentiation is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:0070366 ! regulation of hepatocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0070365 ! positively regulates hepatocyte differentiation relationship: RO:0002213 GO:0070365 ! positively regulates hepatocyte differentiation [Term] id: GO:0070382 name: exocytic vesicle namespace: cellular_component def: "A transport vesicle that mediates transport from an intracellular compartment to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis." [GOC:kad, GOC:mah] synonym: "exocytic constitutive secretory pathway transport vesicle" EXACT [] synonym: "exocytotic vesicle" EXACT [GOC:kad] is_a: GO:0030133 ! transport vesicle is_a: GO:0099503 ! secretory vesicle intersection_of: GO:0030133 ! transport vesicle intersection_of: RO:0002215 GO:0099500 ! capable of vesicle fusion to plasma membrane [Term] id: GO:0070482 name: response to oxygen levels namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen." [GOC:BHF, GOC:mah] is_a: GO:0009628 ! response to abiotic stimulus [Term] id: GO:0070483 name: detection of hypoxia namespace: biological_process def: "The series of events in which a stimulus indicating lowered oxygen tension is received by a cell and converted into a molecular signal. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level." [GOC:BHF, GOC:mah] synonym: "detection of reduced oxygen levels" EXACT [GOC:vk] is_a: GO:0001666 ! response to hypoxia is_a: GO:0003032 ! detection of oxygen [Term] id: GO:0070507 name: regulation of microtubule cytoskeleton organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins." [GOC:mah] synonym: "regulation of microtubule cytoskeleton organisation" EXACT [GOC:mah] synonym: "regulation of microtubule dynamics" EXACT [GOC:dph, GOC:tb] is_a: GO:0032886 ! regulation of microtubule-based process is_a: GO:0051493 ! regulation of cytoskeleton organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0000226 ! regulates (processual) microtubule cytoskeleton organization relationship: RO:0002211 GO:0000226 ! regulates (processual) microtubule cytoskeleton organization [Term] id: GO:0070633 name: transepithelial transport namespace: biological_process def: "The directed movement of a substance from one side of an epithelium to the other." [GOC:mah, GOC:yaf, ISBN:0716731363] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002342 UBERON:0000483 ! results in transport across epithelium relationship: RO:0002342 UBERON:0000483 ! results in transport across epithelium creation_date: 2009-05-06T03:31:02Z [Term] id: GO:0070634 name: transepithelial ammonium transport namespace: biological_process def: "The directed movement of ammonium ions from one side of an epithelium to the other." [GOC:mah, GOC:yaf] is_a: GO:0070633 ! transepithelial transport is_a: GO:0071705 ! nitrogen compound transport intersection_of: GO:0070633 ! transepithelial transport intersection_of: RO:0004009 CHEBI:28938 ! has primary input ammonium relationship: RO:0004009 CHEBI:28938 ! has primary input ammonium creation_date: 2009-05-06T03:34:43Z [Term] id: GO:0070661 name: leukocyte proliferation namespace: biological_process def: "The expansion of a leukocyte population by cell division." [GOC:add] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000738 ! acts on population of leukocyte relationship: RO:0002160 NCBITaxon:7742 ! only in taxon Vertebrata relationship: RO:0002162 NCBITaxon:7742 {all_only="true"} ! in taxon Vertebrata relationship: RO:0012003 CL:0000738 ! acts on population of leukocyte creation_date: 2009-05-28T05:25:28Z [Term] id: GO:0070663 name: regulation of leukocyte proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of leukocyte proliferation." [GOC:add, GOC:mah] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0070661 ! regulates (processual) leukocyte proliferation relationship: RO:0002211 GO:0070661 ! regulates (processual) leukocyte proliferation creation_date: 2009-05-28T05:30:39Z [Term] id: GO:0070664 name: negative regulation of leukocyte proliferation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte proliferation." [GOC:add, GOC:mah] synonym: "down regulation of leukocyte proliferation" EXACT [GOC:mah] synonym: "down-regulation of leukocyte proliferation" EXACT [GOC:mah] synonym: "downregulation of leukocyte proliferation" EXACT [GOC:mah] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0070663 ! regulation of leukocyte proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0070661 ! negatively regulates leukocyte proliferation relationship: RO:0002212 GO:0070661 ! negatively regulates leukocyte proliferation creation_date: 2009-05-28T05:34:50Z [Term] id: GO:0070665 name: positive regulation of leukocyte proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of leukocyte proliferation." [GOC:add, GOC:mah] synonym: "up regulation of leukocyte proliferation" EXACT [GOC:mah] synonym: "up-regulation of leukocyte proliferation" EXACT [GOC:mah] synonym: "upregulation of leukocyte proliferation" EXACT [GOC:mah] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0070663 ! regulation of leukocyte proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0070661 ! positively regulates leukocyte proliferation relationship: RO:0002213 GO:0070661 ! positively regulates leukocyte proliferation creation_date: 2009-05-28T05:36:46Z [Term] id: GO:0070727 name: cellular macromolecule localization namespace: biological_process def: "Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell." [GOC:mah] synonym: "cellular macromolecule localisation" EXACT [GOC:mah] is_a: GO:0033036 ! macromolecule localization is_a: GO:0051641 ! cellular localization creation_date: 2009-06-16T04:08:29Z [Term] id: GO:0070831 name: basement membrane assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form a basement membrane, a part of the extracellular region that consists of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue." [GOC:mah] is_a: GO:0071711 ! basement membrane organization is_a: GO:0085029 ! extracellular matrix assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0005604 ! results in assembly of basement membrane relationship: RO:0002588 GO:0005604 ! results in assembly of basement membrane creation_date: 2009-07-23T05:01:51Z [Term] id: GO:0070857 name: regulation of bile acid biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids." [GOC:BHF, GOC:mah] synonym: "regulation of bile acid anabolism" EXACT [GOC:mah] synonym: "regulation of bile acid biosynthesis" EXACT [GOC:mah] synonym: "regulation of bile acid formation" EXACT [GOC:mah] synonym: "regulation of bile acid synthesis" EXACT [GOC:mah] is_a: GO:0010565 ! regulation of cellular ketone metabolic process is_a: GO:0031326 ! regulation of cellular biosynthetic process is_a: GO:0050810 ! regulation of steroid biosynthetic process is_a: GO:1904251 ! regulation of bile acid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006699 ! regulates (processual) bile acid biosynthetic process relationship: RO:0002211 GO:0006699 ! regulates (processual) bile acid biosynthetic process creation_date: 2009-08-14T03:09:02Z [Term] id: GO:0070858 name: negative regulation of bile acid biosynthetic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids." [GOC:BHF, GOC:mah] synonym: "down regulation of bile acid biosynthetic process" EXACT [GOC:mah] synonym: "down-regulation of bile acid biosynthetic process" EXACT [GOC:mah] synonym: "downregulation of bile acid biosynthetic process" EXACT [GOC:mah] synonym: "negative regulation of bile acid anabolism" EXACT [GOC:mah] synonym: "negative regulation of bile acid biosynthesis" EXACT [GOC:mah] synonym: "negative regulation of bile acid formation" EXACT [GOC:mah] synonym: "negative regulation of bile acid synthesis" EXACT [GOC:mah] is_a: GO:0010894 ! negative regulation of steroid biosynthetic process is_a: GO:0031327 ! negative regulation of cellular biosynthetic process is_a: GO:0070857 ! regulation of bile acid biosynthetic process is_a: GO:1904252 ! negative regulation of bile acid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006699 ! negatively regulates bile acid biosynthetic process relationship: RO:0002212 GO:0006699 ! negatively regulates bile acid biosynthetic process creation_date: 2009-08-14T03:16:40Z [Term] id: GO:0070859 name: positive regulation of bile acid biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids." [GOC:BHF, GOC:mah] synonym: "positive regulation of bile acid anabolism" EXACT [GOC:mah] synonym: "positive regulation of bile acid biosynthesis" EXACT [GOC:mah] synonym: "positive regulation of bile acid formation" EXACT [GOC:mah] synonym: "positive regulation of bile acid synthesis" EXACT [GOC:mah] synonym: "up regulation of bile acid biosynthetic process" EXACT [GOC:mah] synonym: "up-regulation of bile acid biosynthetic process" EXACT [GOC:mah] synonym: "upregulation of bile acid biosynthetic process" EXACT [GOC:mah] is_a: GO:0010893 ! positive regulation of steroid biosynthetic process is_a: GO:0031328 ! positive regulation of cellular biosynthetic process is_a: GO:0070857 ! regulation of bile acid biosynthetic process is_a: GO:1904253 ! positive regulation of bile acid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006699 ! positively regulates bile acid biosynthetic process relationship: RO:0002213 GO:0006699 ! positively regulates bile acid biosynthetic process creation_date: 2009-08-14T03:22:58Z [Term] id: GO:0070873 name: regulation of glycogen metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glycogen." [GOC:mah] synonym: "regulation of glycogen metabolism" EXACT [GOC:mah] is_a: GO:0032881 ! regulation of polysaccharide metabolic process is_a: GO:0043467 ! regulation of generation of precursor metabolites and energy intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0005977 ! regulates (processual) glycogen metabolic process relationship: RO:0002211 GO:0005977 ! regulates (processual) glycogen metabolic process creation_date: 2009-08-20T02:44:53Z [Term] id: GO:0070874 name: negative regulation of glycogen metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glycogen." [GOC:mah] synonym: "negative regulation of glycogen metabolism" EXACT [GOC:mah] is_a: GO:0010605 ! negative regulation of macromolecule metabolic process is_a: GO:0031324 ! negative regulation of cellular metabolic process is_a: GO:0045912 ! negative regulation of carbohydrate metabolic process is_a: GO:0070873 ! regulation of glycogen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0005977 ! negatively regulates glycogen metabolic process relationship: RO:0002212 GO:0005977 ! negatively regulates glycogen metabolic process creation_date: 2009-08-20T02:50:41Z [Term] id: GO:0070875 name: positive regulation of glycogen metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glycogen." [GOC:mah] synonym: "positive regulation of glycogen metabolism" EXACT [GOC:mah] is_a: GO:0010604 ! positive regulation of macromolecule metabolic process is_a: GO:0010907 ! positive regulation of glucose metabolic process is_a: GO:0031325 ! positive regulation of cellular metabolic process is_a: GO:0070873 ! regulation of glycogen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0005977 ! positively regulates glycogen metabolic process relationship: RO:0002213 GO:0005977 ! positively regulates glycogen metabolic process creation_date: 2009-08-20T02:53:55Z [Term] id: GO:0070925 name: organelle assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane." [GOC:mah] is_a: GO:0006996 ! organelle organization is_a: GO:0022607 ! cellular component assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0043226 ! results in assembly of organelle relationship: RO:0002588 GO:0043226 ! results in assembly of organelle creation_date: 2009-09-15T03:00:51Z [Term] id: GO:0070977 name: bone maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for bone to attain its fully functional state." [GOC:dph, GOC:mah] is_a: GO:0048799 ! animal organ maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 UBERON:0001474 ! results in maturation of bone element relationship: BFO:0000050 GO:0060348 ! part of bone development relationship: RO:0002299 UBERON:0001474 ! results in maturation of bone element creation_date: 2009-10-05T04:35:31Z [Term] id: GO:0071168 name: protein localization to chromatin namespace: biological_process def: "Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into chromatin." [GOC:mah] synonym: "protein localisation to chromatin" EXACT [GOC:mah] is_a: GO:0034502 ! protein localization to chromosome intersection_of: GO:0008104 ! protein localization intersection_of: RO:0002339 GO:0000785 ! has target end location chromatin relationship: RO:0002339 GO:0000785 ! has target end location chromatin creation_date: 2009-11-20T11:51:20Z [Term] id: GO:0071169 name: establishment of protein localization to chromatin namespace: biological_process def: "The directed movement of a protein to a part of a chromosome that is organized into chromatin." [GOC:mah] synonym: "establishment of protein localisation to chromatin" EXACT [GOC:mah] is_a: GO:0070199 ! establishment of protein localization to chromosome intersection_of: GO:0045184 ! establishment of protein localization intersection_of: RO:0002339 GO:0000785 ! has target end location chromatin relationship: RO:0002339 GO:0000785 ! has target end location chromatin creation_date: 2009-11-20T11:52:43Z [Term] id: GO:0071425 name: hematopoietic stem cell proliferation namespace: biological_process def: "The expansion of a hematopoietic stem cell population by cell division. A hematopoietic stem cell is a stem cell from which all cells of the lymphoid and myeloid lineages develop." [CL:0000037, GOC:add, GOC:BHF, GOC:mah, GOC:rl] synonym: "hemopoietic stem cell proliferation" EXACT [] is_a: GO:0072089 ! stem cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000037 ! acts on population of hematopoietic stem cell relationship: BFO:0000050 GO:0030097 ! part of hemopoiesis relationship: RO:0012003 CL:0000037 ! acts on population of hematopoietic stem cell creation_date: 2009-12-16T10:22:52Z [Term] id: GO:0071626 name: mastication namespace: biological_process def: "The process of biting and mashing food with the teeth prior to swallowing." [GOC:gvg] synonym: "chewing" EXACT [GOC:mah] is_a: GO:0022600 ! digestive system process creation_date: 2010-02-10T11:19:48Z [Term] id: GO:0071674 name: mononuclear cell migration namespace: biological_process def: "The movement of a mononuclear cell within or between different tissues and organs of the body." [GOC:mah] is_a: GO:0050900 ! leukocyte migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000842 ! results in movement of mononuclear cell relationship: RO:0002565 CL:0000842 ! results in movement of mononuclear cell creation_date: 2010-02-16T02:11:00Z [Term] id: GO:0071675 name: regulation of mononuclear cell migration namespace: biological_process def: "Any process that modulates the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body." [GOC:mah] is_a: GO:0002685 ! regulation of leukocyte migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0071674 ! regulates (processual) mononuclear cell migration relationship: RO:0002211 GO:0071674 ! regulates (processual) mononuclear cell migration creation_date: 2010-02-16T02:11:53Z [Term] id: GO:0071676 name: negative regulation of mononuclear cell migration namespace: biological_process def: "Any process that decreases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body." [GOC:mah] synonym: "down regulation of mononuclear cell migration" EXACT [GOC:mah] synonym: "down-regulation of mononuclear cell migration" EXACT [GOC:mah] synonym: "downregulation of mononuclear cell migration" EXACT [GOC:mah] is_a: GO:0002686 ! negative regulation of leukocyte migration is_a: GO:0071675 ! regulation of mononuclear cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0071674 ! negatively regulates mononuclear cell migration relationship: RO:0002212 GO:0071674 ! negatively regulates mononuclear cell migration creation_date: 2010-02-16T02:13:55Z [Term] id: GO:0071677 name: positive regulation of mononuclear cell migration namespace: biological_process def: "Any process that increases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body." [GOC:mah] synonym: "up regulation of mononuclear cell migration" EXACT [GOC:mah] synonym: "up-regulation of mononuclear cell migration" EXACT [GOC:mah] synonym: "upregulation of mononuclear cell migration" EXACT [GOC:mah] is_a: GO:0002687 ! positive regulation of leukocyte migration is_a: GO:0071675 ! regulation of mononuclear cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0071674 ! positively regulates mononuclear cell migration relationship: RO:0002213 GO:0071674 ! positively regulates mononuclear cell migration creation_date: 2010-02-16T02:15:29Z [Term] id: GO:0071684 name: organism emergence from protective structure namespace: biological_process def: "The developmental process in which an organism emerges from a surrounding protective structure such as an egg or pupa case." [GOC:mah] is_a: GO:0032501 ! multicellular organismal process creation_date: 2010-02-19T04:23:55Z [Term] id: GO:0071692 name: protein localization to extracellular region namespace: biological_process def: "Any process in which a protein is transported from one specific location in the extracellular region to another, or maintained in a specific extracellular location." [GOC:mah] synonym: "protein localisation in extracellular region" EXACT [GOC:mah] synonym: "protein localization in extracellular region" EXACT [] is_a: GO:0008104 ! protein localization intersection_of: GO:0008104 ! protein localization intersection_of: RO:0002339 GO:0005576 ! has target end location extracellular region relationship: RO:0002339 GO:0005576 ! has target end location extracellular region creation_date: 2010-02-25T04:00:13Z [Term] id: GO:0071695 name: anatomical structure maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure to attain its fully functional state." [GOC:mah] is_a: GO:0021700 ! developmental maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 UBERON:0000061 ! results in maturation of anatomical structure relationship: BFO:0000050 GO:0048856 ! part of anatomical structure development relationship: RO:0002299 UBERON:0000061 ! results in maturation of anatomical structure creation_date: 2010-03-02T11:43:38Z [Term] id: GO:0071696 name: ectodermal placode development namespace: biological_process def: "The progression of an ectodermal placode over time from its initial formation until its mature state. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm." [GOC:mah] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005085 ! results in development of ectodermal placode relationship: RO:0002296 UBERON:0005085 ! results in development of ectodermal placode creation_date: 2010-03-02T11:48:01Z [Term] id: GO:0071697 name: ectodermal placode morphogenesis namespace: biological_process def: "The process in which the anatomical structures of an ectodermal placode are generated and organized. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm." [GOC:mah] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0005085 ! results in morphogenesis of ectodermal placode relationship: BFO:0000050 GO:0071696 ! part of ectodermal placode development relationship: RO:0002298 UBERON:0005085 ! results in morphogenesis of ectodermal placode creation_date: 2010-03-02T11:49:51Z [Term] id: GO:0071702 name: organic substance transport namespace: biological_process def: "The directed movement of organic substances into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. An organic substance is a molecular entity that contains carbon." [GOC:mah] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:50860 ! has primary input organic molecular entity relationship: RO:0004009 CHEBI:50860 ! has primary input organic molecular entity creation_date: 2010-03-08T02:15:14Z [Term] id: GO:0071704 name: organic substance metabolic process namespace: biological_process def: "The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon." [GOC:mah] synonym: "organic molecular entity metabolic process" EXACT [] synonym: "organic molecular entity metabolism" EXACT [] synonym: "organic substance metabolism" EXACT [] is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:50860 ! has primary input or output organic molecular entity relationship: RO:0004007 CHEBI:50860 ! has primary input or output organic molecular entity creation_date: 2010-03-08T03:32:18Z [Term] id: GO:0071705 name: nitrogen compound transport namespace: biological_process def: "The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:51143 ! has primary input nitrogen molecular entity relationship: RO:0004009 CHEBI:51143 ! has primary input nitrogen molecular entity creation_date: 2010-03-08T03:56:28Z [Term] id: GO:0071709 name: membrane assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form a membrane." [GOC:mah] is_a: GO:0022607 ! cellular component assembly is_a: GO:0061024 ! membrane organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0016020 ! results in assembly of membrane relationship: BFO:0000050 GO:0044091 ! part of membrane biogenesis relationship: RO:0002588 GO:0016020 ! results in assembly of membrane creation_date: 2010-03-10T11:19:17Z [Term] id: GO:0071711 name: basement membrane organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the basement membrane." [GOC:mah] synonym: "basement membrane organisation" EXACT [GOC:mah] is_a: GO:0030198 ! extracellular matrix organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0005604 ! results in organization of basement membrane relationship: RO:0002592 GO:0005604 ! results in organization of basement membrane creation_date: 2010-03-10T11:57:10Z [Term] id: GO:0071763 name: nuclear membrane organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner or outer membrane." [GOC:mah] synonym: "nuclear membrane organisation" EXACT [GOC:mah] is_a: GO:0061024 ! membrane organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0031965 ! results in organization of nuclear membrane relationship: BFO:0000050 GO:0006998 ! part of nuclear envelope organization relationship: RO:0002592 GO:0031965 ! results in organization of nuclear membrane creation_date: 2010-03-29T03:59:35Z [Term] id: GO:0071764 name: nuclear outer membrane organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear outer membrane." [GOC:mah] synonym: "nuclear outer membrane organisation" EXACT [GOC:mah] is_a: GO:0071763 ! nuclear membrane organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0005640 ! results in organization of nuclear outer membrane relationship: RO:0002592 GO:0005640 ! results in organization of nuclear outer membrane creation_date: 2010-03-29T04:03:37Z [Term] id: GO:0071806 name: protein transmembrane transport namespace: biological_process def: "The process in which a protein is transported across a membrane." [GOC:mah, GOC:vw] synonym: "protein membrane transport" EXACT [] is_a: GO:0045184 ! establishment of protein localization is_a: GO:0055085 ! transmembrane transport is_a: GO:0071702 ! organic substance transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002342 GO:0016020 ! results in transport across membrane intersection_of: RO:0004009 CHEBI:36080 ! has primary input protein creation_date: 2010-09-03T02:54:26Z [Term] id: GO:0071824 name: protein-DNA complex organization namespace: biological_process def: "Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-DNA complex." [GOC:mah] synonym: "DNA-protein complex subunit organization" EXACT [GOC:mah] synonym: "protein-DNA complex subunit organisation" EXACT [GOC:mah] synonym: "protein-DNA complex subunit organization" EXACT [] is_a: GO:0043933 ! protein-containing complex organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0032993 ! results in organization of protein-DNA complex relationship: RO:0002592 GO:0032993 ! results in organization of protein-DNA complex creation_date: 2010-09-08T10:03:26Z [Term] id: GO:0071826 name: protein-RNA complex organization namespace: biological_process def: "Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a ribonucleoprotein complex." [GOC:mah] synonym: "protein-RNA complex subunit organization" EXACT [GOC:mah] synonym: "ribonucleoprotein complex subunit organisation" EXACT [GOC:mah] synonym: "ribonucleoprotein complex subunit organization" EXACT [] synonym: "RNA-protein complex subunit organization" EXACT [GOC:mah] is_a: GO:0043933 ! protein-containing complex organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:1990904 ! results in organization of ribonucleoprotein complex relationship: RO:0002592 GO:1990904 ! results in organization of ribonucleoprotein complex creation_date: 2010-09-08T10:10:35Z [Term] id: GO:0071840 name: cellular component organization or biogenesis namespace: biological_process def: "A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component." [GOC:mah] synonym: "cellular component organisation or biogenesis" EXACT [GOC:mah] synonym: "cellular component organisation or biogenesis at cellular level" EXACT [GOC:mah] synonym: "cellular component organization or biogenesis at cellular level" EXACT [] is_a: GO:0009987 ! cellular process creation_date: 2010-09-10T01:39:16Z [Term] id: GO:0071867 name: response to monoamine namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan." [GOC:mah] synonym: "response to monoamine stimulus" EXACT [GOC:dos] is_a: GO:0010243 ! response to organonitrogen compound intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:63534 ! has primary input monoamine relationship: RO:0004009 CHEBI:63534 ! has primary input monoamine creation_date: 2010-09-13T02:36:37Z [Term] id: GO:0071869 name: response to catecholamine namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution." [GOC:BHF, GOC:mah] synonym: "response to catecholamine stimulus" EXACT [GOC:dos] is_a: GO:0014070 ! response to organic cyclic compound is_a: GO:0071867 ! response to monoamine is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:33567 ! has primary input catecholamine relationship: RO:0004009 CHEBI:33567 ! has primary input catecholamine creation_date: 2010-09-13T02:51:13Z [Term] id: GO:0071873 name: response to norepinephrine namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system." [GOC:BHF, GOC:mah] synonym: "response to noradrenaline stimulus" EXACT [GOC:mah] synonym: "response to norepinephrine stimulus" EXACT [GOC:dos] is_a: GO:0010033 ! response to organic substance is_a: GO:1901698 ! response to nitrogen compound intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:72587 ! has primary input (R)-noradrenaline(1+) relationship: RO:0004009 CHEBI:72587 ! has primary input (R)-noradrenaline(1+) creation_date: 2010-09-13T03:31:53Z [Term] id: GO:0071887 name: leukocyte apoptotic process namespace: biological_process def: "Any apoptotic process in a leukocyte, an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue." [CL:0000738, GOC:BHF, GOC:mah, GOC:mtg_apoptosis] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000738 ! occurs in leukocyte relationship: BFO:0000066 CL:0000738 ! occurs in leukocyte relationship: RO:0002160 NCBITaxon:7742 ! only in taxon Vertebrata relationship: RO:0002162 NCBITaxon:7742 {all_only="true"} ! in taxon Vertebrata creation_date: 2010-09-14T12:44:09Z [Term] id: GO:0071897 name: DNA biosynthetic process namespace: biological_process def: "The biosynthetic process resulting in the formation of DNA." [GOC:mah] synonym: "DNA anabolism" EXACT [GOC:mah] synonym: "DNA biosynthesis" EXACT [GOC:mah] synonym: "DNA formation" EXACT [GOC:mah] synonym: "DNA synthesis" EXACT [GOC:mah] is_a: GO:0006259 ! DNA metabolic process is_a: GO:0009059 ! macromolecule biosynthetic process is_a: GO:0034654 ! nucleobase-containing compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:16991 ! has primary output deoxyribonucleic acid relationship: RO:0004008 CHEBI:16991 ! has primary output deoxyribonucleic acid creation_date: 2010-09-15T02:14:33Z [Term] id: GO:0071944 name: cell periphery namespace: cellular_component def: "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures." [GOC:pdt] is_a: GO:0110165 ! cellular anatomical entity creation_date: 2010-10-04T01:51:47Z [Term] id: GO:0071953 name: elastic fiber namespace: cellular_component def: "An supramolecular fiber that consists of an insoluble core of polymerized tropoelastin monomers and a surrounding mantle of microfibrils. Elastic fibers provide elasticity and recoiling to tissues and organs, and maintain structural integrity against mechanical strain." [GOC:BHF, GOC:mah, PMID:20236620] synonym: "elastic fibre" EXACT [GOC:mah] synonym: "elastin fiber" EXACT [GOC:BHF] is_a: GO:0099512 ! supramolecular fiber relationship: BFO:0000050 GO:0031012 ! part of extracellular matrix creation_date: 2010-10-11T11:44:57Z [Term] id: GO:0071971 name: extracellular exosome assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form an extracellular vesicular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Exosomes are defined by their size, which generally ranges from 30 nm to 100 nm." [GOC:mah, GOC:tfm, PMID:19442504, PMID:27462458] synonym: "extracellular vesicular exosome assembly" EXACT [GOC:vesicles] is_a: GO:0016050 ! vesicle organization is_a: GO:0070925 ! organelle assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0070062 ! results in assembly of extracellular exosome relationship: BFO:0000050 GO:0097734 ! part of extracellular exosome biogenesis relationship: RO:0002588 GO:0070062 ! results in assembly of extracellular exosome creation_date: 2010-10-18T03:44:18Z [Term] id: GO:0072001 name: renal system development namespace: biological_process def: "The process whose specific outcome is the progression of the renal system over time, from its formation to the mature structure. The renal system maintains fluid balance and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels." [GOC:mtg_kidney_jan10, GOC:yaf, http://en.wikibooks.org/wiki/Human_Physiology/The_Urinary_System] is_a: GO:0048731 ! system development intersection_of: GO:0048731 ! system development intersection_of: RO:0002296 UBERON:0001008 ! results in development of renal system relationship: RO:0002296 UBERON:0001008 ! results in development of renal system creation_date: 2010-01-25T10:31:00Z [Term] id: GO:0072003 name: kidney rudiment formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a kidney rudiment from unspecified parts. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0005095 ! results in formation of anatomical entity kidney rudiment relationship: BFO:0000050 GO:0060993 ! part of kidney morphogenesis relationship: RO:0002297 UBERON:0005095 ! results in formation of anatomical entity kidney rudiment creation_date: 2010-01-25T11:18:58Z [Term] id: GO:0072006 name: nephron development namespace: biological_process def: "The process whose specific outcome is the progression of the nephron over time, from its formation to the mature structure. A nephron is the functional unit of the kidney." [GOC:mtg_kidney_jan10] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001285 ! results in development of nephron relationship: BFO:0000050 GO:0001822 ! part of kidney development relationship: RO:0002296 UBERON:0001285 ! results in development of nephron creation_date: 2010-01-25T01:37:16Z [Term] id: GO:0072009 name: nephron epithelium development namespace: biological_process def: "The process whose specific outcome is the progression of the nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The nephron epithelium is a tissue that covers the surface of a nephron." [GOC:mtg_kidney_jan10] is_a: GO:0072073 ! kidney epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004211 ! results in development of nephron epithelium relationship: BFO:0000050 GO:0072006 ! part of nephron development relationship: RO:0002296 UBERON:0004211 ! results in development of nephron epithelium creation_date: 2010-01-25T02:01:39Z [Term] id: GO:0072028 name: nephron morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the nephron are generated and organized. A nephron is the functional unit of the kidney." [GOC:mtg_kidney_jan10] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001285 ! results in morphogenesis of nephron relationship: BFO:0000050 GO:0060993 ! part of kidney morphogenesis relationship: BFO:0000050 GO:0072006 ! part of nephron development relationship: RO:0002298 UBERON:0001285 ! results in morphogenesis of nephron creation_date: 2010-01-25T02:45:52Z [Term] id: GO:0072033 name: renal vesicle formation namespace: biological_process def: "The developmental process pertaining to the initial formation of the renal vesicle from condensed mesenchymal cells. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells." [GOC:mtg_kidney_jan10] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0004209 ! results in formation of anatomical entity renal vesicle relationship: BFO:0000050 GO:0072077 ! part of renal vesicle morphogenesis relationship: RO:0002297 UBERON:0004209 ! results in formation of anatomical entity renal vesicle creation_date: 2010-01-25T02:57:03Z [Term] id: GO:0072036 name: mesenchymal to epithelial transition involved in renal vesicle formation namespace: biological_process def: "A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the renal vesicle." [GOC:mtg_kidney_jan10] is_a: GO:0035850 ! epithelial cell differentiation involved in kidney development is_a: GO:0060231 ! mesenchymal to epithelial transition intersection_of: GO:0060231 ! mesenchymal to epithelial transition intersection_of: BFO:0000050 GO:0072033 ! part of renal vesicle formation relationship: BFO:0000050 GO:0072033 ! part of renal vesicle formation creation_date: 2010-01-25T03:04:24Z [Term] id: GO:0072038 name: mesenchymal stem cell maintenance involved in nephron morphogenesis namespace: biological_process def: "The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells." [GOC:mtg_kidney_jan10] is_a: GO:0035019 ! somatic stem cell population maintenance relationship: BFO:0000050 GO:0072028 ! part of nephron morphogenesis creation_date: 2010-01-25T03:08:05Z [Term] id: GO:0072039 name: regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis namespace: biological_process def: "Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] synonym: "regulation of mesenchymal stem cell apoptotic process involved in nephron morphogenesis" EXACT [] is_a: GO:1902337 ! regulation of apoptotic process involved in morphogenesis is_a: GO:1904672 ! regulation of somatic stem cell population maintenance is_a: GO:2001053 ! regulation of mesenchymal cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1901145 ! regulates (processual) mesenchymal cell apoptotic process involved in nephron morphogenesis relationship: RO:0002211 GO:0072038 ! regulates (processual) mesenchymal stem cell maintenance involved in nephron morphogenesis relationship: RO:0002211 GO:1901145 ! regulates (processual) mesenchymal cell apoptotic process involved in nephron morphogenesis creation_date: 2010-01-25T03:08:34Z [Term] id: GO:0072040 name: negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis namespace: biological_process def: "Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] synonym: "negative regulation of mesenchymal stem cell apoptotic process involved in nephron morphogenesis" EXACT [] is_a: GO:0072039 ! regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis is_a: GO:1902338 ! negative regulation of apoptotic process involved in morphogenesis is_a: GO:1904673 ! negative regulation of somatic stem cell population maintenance is_a: GO:2001054 ! negative regulation of mesenchymal cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1901145 ! negatively regulates mesenchymal cell apoptotic process involved in nephron morphogenesis relationship: RO:0002212 GO:0072038 ! negatively regulates mesenchymal stem cell maintenance involved in nephron morphogenesis relationship: RO:0002212 GO:1901145 ! negatively regulates mesenchymal cell apoptotic process involved in nephron morphogenesis creation_date: 2010-01-25T03:09:30Z [Term] id: GO:0072041 name: positive regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis namespace: biological_process def: "Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] synonym: "positive regulation of mesenchymal stem cell apoptotic process involved in nephron morphogenesis" EXACT [] is_a: GO:0072039 ! regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis is_a: GO:1902339 ! positive regulation of apoptotic process involved in morphogenesis is_a: GO:1904674 ! positive regulation of somatic stem cell population maintenance is_a: GO:2001055 ! positive regulation of mesenchymal cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1901145 ! positively regulates mesenchymal cell apoptotic process involved in nephron morphogenesis relationship: RO:0002213 GO:0072038 ! positively regulates mesenchymal stem cell maintenance involved in nephron morphogenesis relationship: RO:0002213 GO:1901145 ! positively regulates mesenchymal cell apoptotic process involved in nephron morphogenesis creation_date: 2010-01-25T03:10:32Z [Term] id: GO:0072044 name: collecting duct development namespace: biological_process def: "The process whose specific outcome is the progression of a collecting duct over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. It is the final common path through which urine flows before entering the ureter and then emptying into the bladder." [GOC:mtg_kidney_jan10] is_a: GO:0035295 ! tube development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001232 ! results in development of collecting duct of renal tubule relationship: BFO:0000050 GO:0001822 ! part of kidney development relationship: RO:0002296 UBERON:0001232 ! results in development of collecting duct of renal tubule creation_date: 2010-01-25T03:18:06Z [Term] id: GO:0072048 name: renal system pattern specification namespace: biological_process def: "Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate into the anatomical structures of the renal system." [GOC:mtg_kidney_jan10] is_a: GO:0007389 ! pattern specification process relationship: BFO:0000050 GO:0072001 ! part of renal system development creation_date: 2010-01-25T03:31:51Z [Term] id: GO:0072055 name: renal cortex development namespace: biological_process def: "The process whose specific outcome is the progression of the renal cortex over time, from its formation to the mature structure. The renal cortex is the outer region of the kidney." [GOC:mtg_kidney_jan10] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001225 ! results in development of cortex of kidney relationship: BFO:0000050 GO:0001822 ! part of kidney development relationship: RO:0002296 UBERON:0001225 ! results in development of cortex of kidney creation_date: 2010-01-25T04:01:12Z [Term] id: GO:0072059 name: cortical collecting duct development namespace: biological_process def: "The process whose specific outcome is the progression of the cortical collecting duct over time, from its formation to the mature structure. The cortical collecting duct is the portion of the collecting duct that resides in the renal cortex." [GOC:mtg_kidney_jan10] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004203 ! results in development of cortical collecting duct relationship: RO:0002296 UBERON:0004203 ! results in development of cortical collecting duct creation_date: 2010-01-25T04:07:07Z [Term] id: GO:0072071 name: kidney interstitial fibroblast differentiation namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblast of the kidney as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] synonym: "kidney interstitial cell differentiation" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0061005 ! cell differentiation involved in kidney development intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:1000692 ! results in acquisition of features of kidney interstitial fibroblast relationship: RO:0002315 CL:1000692 ! results in acquisition of features of kidney interstitial fibroblast creation_date: 2010-01-25T04:34:31Z [Term] id: GO:0072073 name: kidney epithelium development namespace: biological_process def: "The process whose specific outcome is the progression of an epithelium in the kidney over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure." [GOC:mtg_kidney_jan10] is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004819 ! results in development of kidney epithelium relationship: BFO:0000050 GO:0001822 ! part of kidney development relationship: RO:0002296 UBERON:0004819 ! results in development of kidney epithelium creation_date: 2010-01-25T04:37:42Z [Term] id: GO:0072074 name: kidney mesenchyme development namespace: biological_process def: "The biological process whose specific outcome is the progression of a kidney mesenchyme from an initial condition to its mature state. This process begins with the formation of kidney mesenchyme and ends with the mature structure. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney." [GOC:mtg_kidney_jan10] is_a: GO:0060485 ! mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003918 ! results in development of kidney mesenchyme relationship: BFO:0000050 GO:0001822 ! part of kidney development relationship: RO:0002296 UBERON:0003918 ! results in development of kidney mesenchyme creation_date: 2010-01-25T04:39:04Z [Term] id: GO:0072075 name: metanephric mesenchyme development namespace: biological_process def: "The biological process whose specific outcome is the progression of a metanephric mesenchyme from an initial condition to its mature state. This process begins with the formation of metanephric mesenchyme and ends with the mature structure. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0072074 ! kidney mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003220 ! results in development of metanephric mesenchyme relationship: BFO:0000050 GO:0001656 ! part of metanephros development relationship: RO:0002296 UBERON:0003220 ! results in development of metanephric mesenchyme creation_date: 2010-01-25T04:40:11Z [Term] id: GO:0072076 name: nephrogenic mesenchyme development namespace: biological_process def: "The biological process whose specific outcome is the progression of a nephrogenic mesenchyme from an initial condition to its mature state. This process begins with the formation of nephrogenic mesenchyme and ends with the mature structure. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron." [GOC:mtg_kidney_jan10] is_a: GO:0072074 ! kidney mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004208 ! results in development of nephrogenic mesenchyme relationship: BFO:0000050 GO:0072006 ! part of nephron development relationship: RO:0002296 UBERON:0004208 ! results in development of nephrogenic mesenchyme creation_date: 2010-01-25T04:40:44Z [Term] id: GO:0072077 name: renal vesicle morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the renal vesicle are generated and organized. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells." [GOC:mtg_kidney_jan10] is_a: GO:0002009 ! morphogenesis of an epithelium intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0004209 ! results in morphogenesis of renal vesicle relationship: BFO:0000050 GO:0072087 ! part of renal vesicle development relationship: BFO:0000050 GO:0072088 ! part of nephron epithelium morphogenesis relationship: RO:0002298 UBERON:0004209 ! results in morphogenesis of renal vesicle creation_date: 2010-02-01T02:21:06Z [Term] id: GO:0072078 name: nephron tubule morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a nephron tubule are generated and organized. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney." [GOC:mtg_kidney_jan10] is_a: GO:0061333 ! renal tubule morphogenesis is_a: GO:0072088 ! nephron epithelium morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001231 ! results in morphogenesis of nephron tubule relationship: BFO:0000050 GO:0072080 ! part of nephron tubule development relationship: RO:0002298 UBERON:0001231 ! results in morphogenesis of nephron tubule creation_date: 2010-02-01T02:25:14Z [Term] id: GO:0072079 name: nephron tubule formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a nephron tubule from unspecified parts. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney." [GOC:mtg_kidney_jan10] is_a: GO:0001838 ! embryonic epithelial tube formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0001231 ! results in formation of anatomical entity nephron tubule relationship: BFO:0000050 GO:0072078 ! part of nephron tubule morphogenesis relationship: RO:0002297 UBERON:0001231 ! results in formation of anatomical entity nephron tubule creation_date: 2010-02-01T02:29:26Z [Term] id: GO:0072080 name: nephron tubule development namespace: biological_process def: "The progression of a nephron tubule over time, from its initial formation to the mature structure. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney." [GOC:mtg_kidney_jan10] is_a: GO:0061326 ! renal tubule development is_a: GO:0072009 ! nephron epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001231 ! results in development of nephron tubule relationship: RO:0002296 UBERON:0001231 ! results in development of nephron tubule creation_date: 2010-02-01T02:32:12Z [Term] id: GO:0072087 name: renal vesicle development namespace: biological_process def: "The process whose specific outcome is the progression of the renal vesicle over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells." [GOC:mtg_kidney_jan10] is_a: GO:0072073 ! kidney epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004209 ! results in development of renal vesicle relationship: BFO:0000050 GO:0072009 ! part of nephron epithelium development relationship: RO:0002296 UBERON:0004209 ! results in development of renal vesicle creation_date: 2010-02-08T01:18:31Z [Term] id: GO:0072088 name: nephron epithelium morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the nephron epithelium are generated and organized. The nephron epithelium is a tissue that covers the surface of a nephron." [GOC:mtg_kidney_jan10] is_a: GO:0002009 ! morphogenesis of an epithelium intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0004211 ! results in morphogenesis of nephron epithelium relationship: BFO:0000050 GO:0072009 ! part of nephron epithelium development relationship: BFO:0000050 GO:0072028 ! part of nephron morphogenesis relationship: RO:0002298 UBERON:0004211 ! results in morphogenesis of nephron epithelium creation_date: 2010-02-08T01:19:06Z [Term] id: GO:0072089 name: stem cell proliferation namespace: biological_process def: "The multiplication or reproduction of stem cells, resulting in the expansion of a stem cell population. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [GOC:mtg_kidney_jan10] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000034 ! acts on population of stem cell relationship: BFO:0000051 GO:0017145 ! has part stem cell division relationship: RO:0012003 CL:0000034 ! acts on population of stem cell creation_date: 2010-02-08T02:03:36Z [Term] id: GO:0072091 name: regulation of stem cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of stem cell proliferation. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [GOC:mtg_kidney_jan10] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0072089 ! regulates (processual) stem cell proliferation relationship: RO:0002211 GO:0072089 ! regulates (processual) stem cell proliferation creation_date: 2010-02-08T02:09:03Z [Term] id: GO:0072093 name: metanephric renal vesicle formation namespace: biological_process def: "The developmental process pertaining to the initial formation of the metanephros." [GOC:mtg_kidney_jan10] synonym: "metanephros formation" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0072033 ! renal vesicle formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0005147 ! results in formation of anatomical entity metanephric renal vesicle relationship: BFO:0000050 GO:0072283 ! part of metanephric renal vesicle morphogenesis relationship: RO:0002297 UBERON:0005147 ! results in formation of anatomical entity metanephric renal vesicle creation_date: 2010-02-10T01:17:11Z [Term] id: GO:0072098 name: anterior/posterior pattern specification involved in kidney development namespace: biological_process def: "The developmental process that results in the creation of defined areas or spaces within the kidney along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate." [GOC:mtg_kidney_jan10] synonym: "kidney anterior/posterior pattern specification" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0009952 ! anterior/posterior pattern specification is_a: GO:0061004 ! pattern specification involved in kidney development intersection_of: GO:0009952 ! anterior/posterior pattern specification intersection_of: BFO:0000050 GO:0001822 ! part of kidney development creation_date: 2010-02-10T02:06:24Z [Term] id: GO:0072099 name: anterior/posterior pattern specification involved in ureteric bud development namespace: biological_process def: "The developmental process that results in the creation of defined areas or spaces within the ureteric bud along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate." [GOC:mtg_kidney_jan10] is_a: GO:0061227 ! pattern specification involved in mesonephros development is_a: GO:0072098 ! anterior/posterior pattern specification involved in kidney development intersection_of: GO:0009952 ! anterior/posterior pattern specification intersection_of: BFO:0000050 GO:0001657 ! part of ureteric bud development relationship: BFO:0000050 GO:0001657 ! part of ureteric bud development creation_date: 2010-02-10T02:12:09Z [Term] id: GO:0072105 name: ureteric peristalsis namespace: biological_process def: "A wavelike sequence of involuntary muscular contraction and relaxation that passes along the ureter, impelling the contents onwards. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder." [GOC:mtg_kidney_jan10] is_a: GO:0014849 ! ureter smooth muscle contraction is_a: GO:0030432 ! peristalsis intersection_of: GO:0030432 ! peristalsis intersection_of: BFO:0000066 UBERON:0000056 ! occurs in ureter relationship: BFO:0000066 UBERON:0000056 ! occurs in ureter creation_date: 2010-02-10T03:07:54Z [Term] id: GO:0072106 name: regulation of ureteric bud formation namespace: biological_process def: "Any process that modulates the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct." [GOC:mtg_kidney_jan10] is_a: GO:0061217 ! regulation of mesonephros development is_a: GO:1905276 ! regulation of epithelial tube formation is_a: GO:2000027 ! regulation of animal organ morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060676 ! regulates (processual) ureteric bud formation relationship: RO:0002211 GO:0060676 ! regulates (processual) ureteric bud formation creation_date: 2010-02-12T02:34:40Z [Term] id: GO:0072107 name: positive regulation of ureteric bud formation namespace: biological_process def: "Any process that increases the rate or extent of the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct." [GOC:mtg_kidney_jan10] is_a: GO:0072106 ! regulation of ureteric bud formation is_a: GO:0110110 ! positive regulation of animal organ morphogenesis is_a: GO:1905278 ! positive regulation of epithelial tube formation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060676 ! positively regulates ureteric bud formation relationship: RO:0002213 GO:0060676 ! positively regulates ureteric bud formation creation_date: 2010-02-12T02:37:28Z [Term] id: GO:0072108 name: positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis namespace: biological_process def: "Any process that increases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0003339 ! regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium is_a: GO:2000698 ! positive regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0003337 ! positively regulates mesenchymal to epithelial transition involved in metanephros morphogenesis relationship: RO:0002213 GO:0003337 ! positively regulates mesenchymal to epithelial transition involved in metanephros morphogenesis creation_date: 2010-02-12T02:45:57Z [Term] id: GO:0072111 name: cell proliferation involved in kidney development namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of the population in the kidney." [GOC:mtg_kidney_jan10] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: BFO:0000050 GO:0001822 ! part of kidney development relationship: BFO:0000050 GO:0001822 ! part of kidney development creation_date: 2010-02-22T10:48:45Z [Term] id: GO:0072114 name: pronephros morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the pronephros are generated and organized. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life." [GOC:mtg_kidney_jan10] synonym: "pronephric kidney morphogenesis" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0060993 ! kidney morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002120 ! results in morphogenesis of pronephros relationship: BFO:0000050 GO:0048793 ! part of pronephros development relationship: RO:0002298 UBERON:0002120 ! results in morphogenesis of pronephros creation_date: 2010-02-22T11:12:15Z [Term] id: GO:0072116 name: pronephros formation namespace: biological_process def: "The developmental process pertaining to the initial formation of the pronephros. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life." [GOC:mtg_kidney_jan10] synonym: "pronephric kidney formation" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0048645 ! animal organ formation is_a: GO:0072003 ! kidney rudiment formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0002120 ! results in formation of anatomical entity pronephros relationship: BFO:0000050 GO:0072114 ! part of pronephros morphogenesis relationship: RO:0002297 UBERON:0002120 ! results in formation of anatomical entity pronephros creation_date: 2010-02-22T11:16:26Z [Term] id: GO:0072120 name: pronephros maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for the pronephros to attain its fully functional state. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life." [GOC:mtg_kidney_jan10] synonym: "pronephric kidney maturation" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0048799 ! animal organ maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 UBERON:0002120 ! results in maturation of pronephros relationship: BFO:0000050 GO:0048793 ! part of pronephros development relationship: RO:0002299 UBERON:0002120 ! results in maturation of pronephros creation_date: 2010-02-22T11:25:48Z [Term] id: GO:0072127 name: renal capsule development namespace: biological_process def: "The process whose specific outcome is the progression of the renal capsule over time, from its formation to the mature structure. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands." [GOC:mtg_kidney_jan10] is_a: GO:0061448 ! connective tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002015 ! results in development of kidney capsule relationship: BFO:0000050 GO:0001822 ! part of kidney development relationship: RO:0002296 UBERON:0002015 ! results in development of kidney capsule creation_date: 2010-02-22T02:02:55Z [Term] id: GO:0072128 name: renal capsule morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the renal capsule are generated and organized. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands." [GOC:mtg_kidney_jan10] is_a: GO:0048729 ! tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002015 ! results in morphogenesis of kidney capsule relationship: BFO:0000050 GO:0072127 ! part of renal capsule development relationship: RO:0002298 UBERON:0002015 ! results in morphogenesis of kidney capsule creation_date: 2010-02-22T02:06:19Z [Term] id: GO:0072129 name: renal capsule formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a renal capsule from unspecified parts. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands." [GOC:mtg_kidney_jan10] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0002015 ! results in formation of anatomical entity kidney capsule relationship: BFO:0000050 GO:0072128 ! part of renal capsule morphogenesis relationship: RO:0002297 UBERON:0002015 ! results in formation of anatomical entity kidney capsule creation_date: 2010-02-22T02:08:14Z [Term] id: GO:0072131 name: kidney mesenchyme morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a kidney mesenchymal tissue are generated and organized. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney." [GOC:mtg_kidney_jan10] is_a: GO:0072132 ! mesenchyme morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003918 ! results in morphogenesis of kidney mesenchyme relationship: BFO:0000050 GO:0072074 ! part of kidney mesenchyme development relationship: RO:0002298 UBERON:0003918 ! results in morphogenesis of kidney mesenchyme creation_date: 2010-02-22T02:16:43Z [Term] id: GO:0072132 name: mesenchyme morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a mesenchymal tissue are generated and organized. A mesenchymal tissue is made up of loosely packed stellate cells." [GOC:mtg_kidney_jan10] is_a: GO:0048729 ! tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003104 ! results in morphogenesis of mesenchyme relationship: BFO:0000050 GO:0009887 ! part of animal organ morphogenesis relationship: BFO:0000050 GO:0060485 ! part of mesenchyme development relationship: RO:0002298 UBERON:0003104 ! results in morphogenesis of mesenchyme creation_date: 2010-02-22T02:17:15Z [Term] id: GO:0072133 name: metanephric mesenchyme morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a metanephric mesenchymal tissue are generated and organized. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0072131 ! kidney mesenchyme morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003220 ! results in morphogenesis of metanephric mesenchyme relationship: BFO:0000050 GO:0072075 ! part of metanephric mesenchyme development relationship: RO:0002298 UBERON:0003220 ! results in morphogenesis of metanephric mesenchyme creation_date: 2010-02-22T02:20:14Z [Term] id: GO:0072134 name: nephrogenic mesenchyme morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a nephrogenic mesenchymal tissue are generated and organized. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron." [GOC:mtg_kidney_jan10] is_a: GO:0072131 ! kidney mesenchyme morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0004208 ! results in morphogenesis of nephrogenic mesenchyme relationship: BFO:0000050 GO:0072076 ! part of nephrogenic mesenchyme development relationship: RO:0002298 UBERON:0004208 ! results in morphogenesis of nephrogenic mesenchyme creation_date: 2010-02-22T02:21:16Z [Term] id: GO:0072138 name: mesenchymal cell proliferation involved in ureteric bud development namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureteric bud, that contributes to ureteric bud development." [GOC:mtg_kidney_jan10] is_a: GO:0010463 ! mesenchymal cell proliferation is_a: GO:0061209 ! cell proliferation involved in mesonephros development intersection_of: GO:0010463 ! mesenchymal cell proliferation intersection_of: BFO:0000050 GO:0001657 ! part of ureteric bud development relationship: BFO:0000050 GO:0001657 ! part of ureteric bud development creation_date: 2010-02-22T02:40:38Z [Term] id: GO:0072141 name: renal interstitial fibroblast development namespace: biological_process def: "The process whose specific outcome is the progression of a renal interstitial fibroblast over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10] synonym: "kidney interstitial cell development" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0048468 ! cell development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 CL:1000692 ! results in development of kidney interstitial fibroblast relationship: BFO:0000050 GO:0072071 ! part of kidney interstitial fibroblast differentiation relationship: RO:0002296 CL:1000692 ! results in development of kidney interstitial fibroblast creation_date: 2010-02-24T01:39:05Z [Term] id: GO:0072155 name: epithelial cell migration involved in nephron tubule morphogenesis namespace: biological_process def: "The orderly movement of epithelial cells within a renal tubule that contributes to nephron tubule morphogenesis." [GOC:mtg_kidney_jan10] is_a: GO:0010631 ! epithelial cell migration is_a: GO:0035787 ! cell migration involved in kidney development intersection_of: GO:0010631 ! epithelial cell migration intersection_of: BFO:0000050 GO:0072078 ! part of nephron tubule morphogenesis relationship: BFO:0000050 GO:0072078 ! part of nephron tubule morphogenesis creation_date: 2010-02-24T02:21:25Z [Term] id: GO:0072160 name: nephron tubule epithelial cell differentiation namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the nephron tubule as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] is_a: GO:0035850 ! epithelial cell differentiation involved in kidney development intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:1000494 ! results in acquisition of features of nephron tubule epithelial cell relationship: BFO:0000050 GO:0072080 ! part of nephron tubule development relationship: RO:0002315 CL:1000494 ! results in acquisition of features of nephron tubule epithelial cell creation_date: 2010-02-24T02:40:11Z [Term] id: GO:0072161 name: mesenchymal cell differentiation involved in kidney development namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the kidney as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] is_a: GO:0061005 ! cell differentiation involved in kidney development is_a: GO:2001012 ! mesenchymal cell differentiation involved in renal system development intersection_of: GO:0048762 ! mesenchymal cell differentiation intersection_of: BFO:0000050 GO:0001822 ! part of kidney development relationship: BFO:0000050 GO:0072074 ! part of kidney mesenchyme development creation_date: 2010-02-26T01:31:49Z [Term] id: GO:0072163 name: mesonephric epithelium development namespace: biological_process def: "The process whose specific outcome is the progression of an epithelium in the mesonephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure." [GOC:mtg_kidney_jan10] is_a: GO:0072073 ! kidney epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005103 ! results in development of mesonephric epithelium relationship: BFO:0000050 GO:0001823 ! part of mesonephros development relationship: RO:0002296 UBERON:0005103 ! results in development of mesonephric epithelium creation_date: 2010-02-26T01:40:43Z [Term] id: GO:0072164 name: mesonephric tubule development namespace: biological_process def: "The progression of a mesonephric tubule over time, from its initial formation to the mature structure. A mesonephric tubule is an epithelial tube that is part of the mesonephros." [GOC:mtg_kidney_jan10] is_a: GO:0035295 ! tube development is_a: GO:0072163 ! mesonephric epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000083 ! results in development of mesonephric tubule relationship: RO:0002296 UBERON:0000083 ! results in development of mesonephric tubule creation_date: 2010-02-26T01:45:58Z [Term] id: GO:0072170 name: metanephric tubule development namespace: biological_process def: "The progression of a metanephric tubule over time, from its initial formation to the mature structure. A metanephric tubule is an epithelial tube that is part of the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0035295 ! tube development is_a: GO:0072207 ! metanephric epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005106 ! results in development of metanephric tubule relationship: RO:0002296 UBERON:0005106 ! results in development of metanephric tubule creation_date: 2010-02-26T01:58:18Z [Term] id: GO:0072171 name: mesonephric tubule morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a mesonephric tubule are generated and organized. A mesonephric tubule is an epithelial tube that is part of the mesonephros." [GOC:mtg_kidney_jan10] is_a: GO:0072078 ! nephron tubule morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000083 ! results in morphogenesis of mesonephric tubule relationship: BFO:0000050 GO:0072164 ! part of mesonephric tubule development relationship: RO:0002298 UBERON:0000083 ! results in morphogenesis of mesonephric tubule creation_date: 2010-02-26T02:02:13Z [Term] id: GO:0072172 name: mesonephric tubule formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a mesonephric tubule from unspecified parts. A mesonephric tubule is an epithelial tube that is part of the mesonephros." [GOC:mtg_kidney_jan10] is_a: GO:0072079 ! nephron tubule formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0000083 ! results in formation of anatomical entity mesonephric tubule relationship: BFO:0000050 GO:0072171 ! part of mesonephric tubule morphogenesis relationship: RO:0002297 UBERON:0000083 ! results in formation of anatomical entity mesonephric tubule creation_date: 2010-02-26T02:02:37Z [Term] id: GO:0072173 name: metanephric tubule morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a metanephric tubule are generated and organized from an epithelium. A metanephric tubule is an epithelial tube that is part of the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0060562 ! epithelial tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0005106 ! results in morphogenesis of metanephric tubule relationship: BFO:0000050 GO:0072170 ! part of metanephric tubule development relationship: RO:0002298 UBERON:0005106 ! results in morphogenesis of metanephric tubule creation_date: 2010-02-26T02:06:42Z [Term] id: GO:0072174 name: metanephric tubule formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a metanephric tubule." [GOC:mtg_kidney_jan10] is_a: GO:0072175 ! epithelial tube formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0005106 ! results in formation of anatomical entity metanephric tubule relationship: BFO:0000050 GO:0072173 ! part of metanephric tubule morphogenesis relationship: RO:0002297 UBERON:0005106 ! results in formation of anatomical entity metanephric tubule creation_date: 2010-02-26T02:07:41Z [Term] id: GO:0072175 name: epithelial tube formation namespace: biological_process def: "The developmental process pertaining to the initial formation of an epithelial tube." [GOC:mtg_kidney_jan10] is_a: GO:0035148 ! tube formation intersection_of: GO:0035148 ! tube formation intersection_of: RO:0002297 UBERON:0003914 ! results in formation of anatomical entity epithelial tube relationship: BFO:0000050 GO:0060562 ! part of epithelial tube morphogenesis relationship: RO:0002297 UBERON:0003914 ! results in formation of anatomical entity epithelial tube creation_date: 2010-02-26T02:15:40Z [Term] id: GO:0072176 name: nephric duct development namespace: biological_process def: "The process whose specific outcome is the progression of a nephric duct over time, from its initial formation to a mature structure. A nephric duct is a tube that drains a primitive kidney." [GOC:mtg_kidney_jan10] is_a: GO:0035295 ! tube development is_a: GO:0072073 ! kidney epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0009201 ! results in development of nephric duct relationship: RO:0002296 UBERON:0009201 ! results in development of nephric duct creation_date: 2010-02-26T02:27:31Z [Term] id: GO:0072177 name: mesonephric duct development namespace: biological_process def: "The process whose specific outcome is the progression of a mesonephric duct over time, from its initial formation to a mature structure. A mesonephric duct is a tube drains the mesonephros." [GOC:mtg_kidney_jan10] synonym: "Wolffian duct development" EXACT [GOC:dph] is_a: GO:0072164 ! mesonephric tubule development is_a: GO:0072176 ! nephric duct development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003074 ! results in development of mesonephric duct relationship: RO:0002296 UBERON:0003074 ! results in development of mesonephric duct creation_date: 2010-02-26T02:32:22Z [Term] id: GO:0072178 name: nephric duct morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the nephric duct are generated and organized. A nephric duct is a tube that drains a primitive kidney." [GOC:mtg_kidney_jan10] is_a: GO:0060562 ! epithelial tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0009201 ! results in morphogenesis of nephric duct relationship: BFO:0000050 GO:0072176 ! part of nephric duct development relationship: RO:0002298 UBERON:0009201 ! results in morphogenesis of nephric duct creation_date: 2010-02-26T02:35:29Z [Term] id: GO:0072179 name: nephric duct formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a nephric duct. A nephric duct is a tube that drains a primitive kidney." [GOC:mtg_kidney_jan10] is_a: GO:0072175 ! epithelial tube formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0009201 ! results in formation of anatomical entity nephric duct relationship: BFO:0000050 GO:0072178 ! part of nephric duct morphogenesis relationship: RO:0002297 UBERON:0009201 ! results in formation of anatomical entity nephric duct creation_date: 2010-02-26T02:35:55Z [Term] id: GO:0072180 name: mesonephric duct morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the mesonephric duct are generated and organized. A mesonephric duct is a tube drains the mesonephros." [GOC:mtg_kidney_jan10] is_a: GO:0072171 ! mesonephric tubule morphogenesis is_a: GO:0072178 ! nephric duct morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003074 ! results in morphogenesis of mesonephric duct relationship: BFO:0000050 GO:0072177 ! part of mesonephric duct development relationship: RO:0002298 UBERON:0003074 ! results in morphogenesis of mesonephric duct creation_date: 2010-02-26T02:37:13Z [Term] id: GO:0072181 name: mesonephric duct formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a mesonephric duct. A mesonephric duct is a tube that drains the mesonephros." [GOC:mtg_kidney_jan10] synonym: "Wolffian duct formation" EXACT [GOC:dph] is_a: GO:0072172 ! mesonephric tubule formation is_a: GO:0072179 ! nephric duct formation is_a: GO:0072180 ! mesonephric duct morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0003074 ! results in formation of anatomical entity mesonephric duct relationship: RO:0002297 UBERON:0003074 ! results in formation of anatomical entity mesonephric duct creation_date: 2010-02-26T02:38:03Z [Term] id: GO:0072182 name: regulation of nephron tubule epithelial cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of nephron tubule epithelial cell differentiation." [GOC:mtg_kidney_jan10] is_a: GO:2000696 ! regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0072160 ! regulates (processual) nephron tubule epithelial cell differentiation relationship: RO:0002211 GO:0072160 ! regulates (processual) nephron tubule epithelial cell differentiation creation_date: 2010-02-26T02:45:09Z [Term] id: GO:0072183 name: negative regulation of nephron tubule epithelial cell differentiation namespace: biological_process def: "Any process that decreases the frequency, rate or extent of nephron tubule epithelial cell differentiation." [GOC:mtg_kidney_jan10] is_a: GO:0072182 ! regulation of nephron tubule epithelial cell differentiation is_a: GO:0090185 ! negative regulation of kidney development is_a: GO:2000697 ! negative regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0072160 ! negatively regulates nephron tubule epithelial cell differentiation relationship: RO:0002212 GO:0072160 ! negatively regulates nephron tubule epithelial cell differentiation creation_date: 2010-02-26T02:47:25Z [Term] id: GO:0072189 name: ureter development namespace: biological_process def: "The process whose specific outcome is the progression of the ureter over time, from its formation to the mature structure. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut." [GOC:mtg_kidney_jan10] is_a: GO:0035295 ! tube development is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000056 ! results in development of ureter relationship: BFO:0000050 GO:0072001 ! part of renal system development relationship: RO:0002296 UBERON:0000056 ! results in development of ureter creation_date: 2010-03-01T01:44:14Z [Term] id: GO:0072191 name: ureter smooth muscle development namespace: biological_process def: "The process whose specific outcome is the progression of smooth muscle in the ureter over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10] is_a: GO:0048745 ! smooth muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0009919 ! results in development of ureter smooth muscle relationship: BFO:0000050 GO:0072189 ! part of ureter development relationship: RO:0002296 UBERON:0009919 ! results in development of ureter smooth muscle creation_date: 2010-03-01T01:48:53Z [Term] id: GO:0072193 name: ureter smooth muscle cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell in the ureter." [GOC:mtg_kidney_jan10] is_a: GO:0051145 ! smooth muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:1000979 ! results in acquisition of features of ureter smooth muscle cell relationship: BFO:0000050 GO:0072191 ! part of ureter smooth muscle development relationship: RO:0002315 CL:1000979 ! results in acquisition of features of ureter smooth muscle cell creation_date: 2010-03-01T01:55:01Z [Term] id: GO:0072194 name: kidney smooth muscle tissue development namespace: biological_process def: "The process whose specific outcome is the progression of smooth muscle in the kidney over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10] is_a: GO:0048745 ! smooth muscle tissue development relationship: BFO:0000050 GO:0001822 ! part of kidney development creation_date: 2010-03-01T02:05:30Z [Term] id: GO:0072197 name: ureter morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the ureter are generated and organized. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder." [GOC:mtg_kidney_jan10] is_a: GO:0009887 ! animal organ morphogenesis is_a: GO:0035239 ! tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000056 ! results in morphogenesis of ureter relationship: BFO:0000050 GO:0072189 ! part of ureter development relationship: RO:0002298 UBERON:0000056 ! results in morphogenesis of ureter creation_date: 2010-03-01T02:24:55Z [Term] id: GO:0072198 name: mesenchymal cell proliferation involved in ureter development namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureter, that contributes to ureter development." [GOC:mtg_kidney_jan10] is_a: GO:0010463 ! mesenchymal cell proliferation intersection_of: GO:0010463 ! mesenchymal cell proliferation intersection_of: BFO:0000050 GO:0072189 ! part of ureter development relationship: BFO:0000050 GO:0072189 ! part of ureter development creation_date: 2010-03-01T03:24:41Z [Term] id: GO:0072199 name: regulation of mesenchymal cell proliferation involved in ureter development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." [GOC:mtg_kidney_jan10] is_a: GO:0010464 ! regulation of mesenchymal cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0072198 ! regulates (processual) mesenchymal cell proliferation involved in ureter development relationship: RO:0002211 GO:0072198 ! regulates (processual) mesenchymal cell proliferation involved in ureter development creation_date: 2010-03-01T03:38:13Z [Term] id: GO:0072200 name: negative regulation of mesenchymal cell proliferation involved in ureter development namespace: biological_process def: "Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." [GOC:mtg_kidney_jan10] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:0072199 ! regulation of mesenchymal cell proliferation involved in ureter development is_a: GO:0072201 ! negative regulation of mesenchymal cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0072198 ! negatively regulates mesenchymal cell proliferation involved in ureter development relationship: RO:0002212 GO:0072198 ! negatively regulates mesenchymal cell proliferation involved in ureter development creation_date: 2010-03-01T03:42:31Z [Term] id: GO:0072201 name: negative regulation of mesenchymal cell proliferation namespace: biological_process def: "Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." [GOC:mtg_kidney_jan10] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0010464 ! regulation of mesenchymal cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0010463 ! negatively regulates mesenchymal cell proliferation relationship: RO:0002212 GO:0010463 ! negatively regulates mesenchymal cell proliferation creation_date: 2010-03-01T03:43:29Z [Term] id: GO:0072202 name: cell differentiation involved in metanephros development namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephros as it progresses from its formation to the mature state." [GOC:mah, GOC:mtg_kidney_jan10] is_a: GO:0061005 ! cell differentiation involved in kidney development intersection_of: GO:0030154 ! cell differentiation intersection_of: BFO:0000050 GO:0001656 ! part of metanephros development relationship: BFO:0000050 GO:0001656 ! part of metanephros development creation_date: 2010-03-18T10:40:14Z [Term] id: GO:0072203 name: cell proliferation involved in metanephros development namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of the population in the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0072111 ! cell proliferation involved in kidney development intersection_of: GO:0008283 ! cell population proliferation intersection_of: BFO:0000050 GO:0001656 ! part of metanephros development relationship: BFO:0000050 GO:0001656 ! part of metanephros development creation_date: 2010-03-18T10:42:27Z [Term] id: GO:0072204 name: cell-cell signaling involved in metanephros development namespace: biological_process def: "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the metanephros over time, from its formation to the mature organ." [GOC:mtg_kidney_jan10] synonym: "cell-cell signalling involved in metanephros development" EXACT [GOC:mah] is_a: GO:0060995 ! cell-cell signaling involved in kidney development intersection_of: GO:0007267 ! cell-cell signaling intersection_of: BFO:0000050 GO:0001656 ! part of metanephros development relationship: BFO:0000050 GO:0001656 ! part of metanephros development creation_date: 2010-03-18T10:54:36Z [Term] id: GO:0072205 name: metanephric collecting duct development namespace: biological_process def: "The process whose specific outcome is the progression of a collecting duct in the metanephros over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder." [GOC:mtg_kidney_jan10] is_a: GO:0072044 ! collecting duct development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004737 ! results in development of metanephric collecting duct relationship: BFO:0000050 GO:0001656 ! part of metanephros development relationship: RO:0002296 UBERON:0004737 ! results in development of metanephric collecting duct creation_date: 2010-03-18T11:15:37Z [Term] id: GO:0072207 name: metanephric epithelium development namespace: biological_process def: "The process whose specific outcome is the progression of an epithelium in the metanephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure." [GOC:mtg_kidney_jan10] is_a: GO:0072073 ! kidney epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005108 ! results in development of metanephric epithelium relationship: BFO:0000050 GO:0001656 ! part of metanephros development relationship: RO:0002296 UBERON:0005108 ! results in development of metanephric epithelium creation_date: 2010-03-18T11:50:37Z [Term] id: GO:0072208 name: metanephric smooth muscle tissue development namespace: biological_process def: "The process whose specific outcome is the progression of smooth muscle in the metanephros over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10] is_a: GO:0072194 ! kidney smooth muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005109 ! results in development of metanephric smooth muscle tissue relationship: BFO:0000050 GO:0001656 ! part of metanephros development relationship: RO:0002296 UBERON:0005109 ! results in development of metanephric smooth muscle tissue creation_date: 2010-03-18T11:51:59Z [Term] id: GO:0072210 name: metanephric nephron development namespace: biological_process def: "The process whose specific outcome is the progression of a nephron in the metanephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney." [GOC:mtg_kidney_jan10] is_a: GO:0072006 ! nephron development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005110 ! results in development of metanephric nephron relationship: BFO:0000050 GO:0001656 ! part of metanephros development relationship: RO:0002296 UBERON:0005110 ! results in development of metanephric nephron creation_date: 2010-03-18T12:52:57Z [Term] id: GO:0072213 name: metanephric capsule development namespace: biological_process def: "The process whose specific outcome is the progression of the metanephric capsule over time, from its formation to the mature structure. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage." [GOC:mtg_kidney_jan10] is_a: GO:0072127 ! renal capsule development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005137 ! results in development of metanephric capsule relationship: BFO:0000050 GO:0001656 ! part of metanephros development relationship: RO:0002296 UBERON:0005137 ! results in development of metanephric capsule creation_date: 2010-03-18T01:25:19Z [Term] id: GO:0072214 name: metanephric cortex development namespace: biological_process def: "The process whose specific outcome is the progression of the metanephric cortex over time, from its formation to the mature structure. The metanephric cortex is the outer region of the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0060485 ! mesenchyme development is_a: GO:0072055 ! renal cortex development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005113 ! results in development of metanephric cortex mesenchyme relationship: BFO:0000050 GO:0001656 ! part of metanephros development relationship: RO:0002296 UBERON:0005113 ! results in development of metanephric cortex mesenchyme creation_date: 2010-03-18T01:29:49Z [Term] id: GO:0072215 name: regulation of metanephros development namespace: biological_process def: "Any process that modulates the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10] is_a: GO:0090183 ! regulation of kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001656 ! regulates (processual) metanephros development relationship: RO:0002211 GO:0001656 ! regulates (processual) metanephros development [Term] id: GO:0072216 name: positive regulation of metanephros development namespace: biological_process def: "Any process that increases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10] is_a: GO:0072215 ! regulation of metanephros development is_a: GO:0090184 ! positive regulation of kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001656 ! positively regulates metanephros development relationship: RO:0002213 GO:0001656 ! positively regulates metanephros development creation_date: 2010-03-18T01:40:12Z [Term] id: GO:0072217 name: negative regulation of metanephros development namespace: biological_process def: "Any process that decreases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10] is_a: GO:0072215 ! regulation of metanephros development is_a: GO:0090185 ! negative regulation of kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001656 ! negatively regulates metanephros development relationship: RO:0002212 GO:0001656 ! negatively regulates metanephros development creation_date: 2010-03-18T01:45:48Z [Term] id: GO:0072219 name: metanephric cortical collecting duct development namespace: biological_process def: "The process whose specific outcome is the progression of the metanephric cortical collecting duct over time, from its formation to the mature structure. The metanephric cortical collecting duct is the portion of the metanephric collecting duct that resides in the renal cortex." [GOC:mtg_kidney_jan10] is_a: GO:0072059 ! cortical collecting duct development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005115 ! results in development of metanephric cortical collecting duct relationship: RO:0002296 UBERON:0005115 ! results in development of metanephric cortical collecting duct creation_date: 2010-03-18T03:34:52Z [Term] id: GO:0072234 name: metanephric nephron tubule development namespace: biological_process def: "The progression of a metanephric nephron tubule over time, from its initial formation to the mature structure. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0072080 ! nephron tubule development is_a: GO:0072170 ! metanephric tubule development is_a: GO:0072243 ! metanephric nephron epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005146 ! results in development of metanephric nephron tubule relationship: RO:0002296 UBERON:0005146 ! results in development of metanephric nephron tubule creation_date: 2010-03-18T03:41:23Z [Term] id: GO:0072243 name: metanephric nephron epithelium development namespace: biological_process def: "The process whose specific outcome is the progression of the metanephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The metanephric nephron epithelium is a tissue that covers the surface of a nephron in the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0072009 ! nephron epithelium development is_a: GO:0072207 ! metanephric epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005134 ! results in development of metanephric nephron epithelium relationship: RO:0002296 UBERON:0005134 ! results in development of metanephric nephron epithelium creation_date: 2010-03-19T03:29:49Z [Term] id: GO:0072257 name: metanephric nephron tubule epithelial cell differentiation namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephric nephron tubule as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] is_a: GO:0072160 ! nephron tubule epithelial cell differentiation is_a: GO:0072202 ! cell differentiation involved in metanephros development intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:1000123 ! results in acquisition of features of metanephric nephron tubule epithelial cell relationship: BFO:0000050 GO:0072234 ! part of metanephric nephron tubule development relationship: RO:0002315 CL:1000123 ! results in acquisition of features of metanephric nephron tubule epithelial cell creation_date: 2010-03-19T04:11:02Z [Term] id: GO:0072265 name: metanephric capsule morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the metanephric capsule are generated and organized. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage." [GOC:mtg_kidney_jan10] is_a: GO:0072128 ! renal capsule morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0005137 ! results in morphogenesis of metanephric capsule relationship: BFO:0000050 GO:0072213 ! part of metanephric capsule development relationship: RO:0002298 UBERON:0005137 ! results in morphogenesis of metanephric capsule creation_date: 2010-03-30T02:54:49Z [Term] id: GO:0072266 name: metanephric capsule formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a metanephric capsule from unspecified parts. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage." [GOC:mtg_kidney_jan10] is_a: GO:0072129 ! renal capsule formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0005137 ! results in formation of anatomical entity metanephric capsule relationship: BFO:0000050 GO:0072265 ! part of metanephric capsule morphogenesis relationship: RO:0002297 UBERON:0005137 ! results in formation of anatomical entity metanephric capsule creation_date: 2010-03-30T02:56:35Z [Term] id: GO:0072268 name: pattern specification involved in metanephros development namespace: biological_process def: "Any developmental process that results in the creation of defined areas or spaces within the metanephros to which cells respond and eventually are instructed to differentiate." [GOC:mtg_kidney_jan10] synonym: "metanephros pattern specification" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0061004 ! pattern specification involved in kidney development intersection_of: GO:0007389 ! pattern specification process intersection_of: BFO:0000050 GO:0001656 ! part of metanephros development relationship: BFO:0000050 GO:0001656 ! part of metanephros development creation_date: 2010-03-30T03:06:30Z [Term] id: GO:0072273 name: metanephric nephron morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the metanephric nephron are generated and organized. A metanephric nephron is the functional unit of the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0072028 ! nephron morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0005110 ! results in morphogenesis of metanephric nephron relationship: BFO:0000050 GO:0003338 ! part of metanephros morphogenesis relationship: BFO:0000050 GO:0072210 ! part of metanephric nephron development relationship: RO:0002298 UBERON:0005110 ! results in morphogenesis of metanephric nephron creation_date: 2010-03-30T03:33:19Z [Term] id: GO:0072282 name: metanephric nephron tubule morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a metanephric nephron tubule are generated and organized. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0072078 ! nephron tubule morphogenesis is_a: GO:0072173 ! metanephric tubule morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0005146 ! results in morphogenesis of metanephric nephron tubule relationship: BFO:0000050 GO:0072234 ! part of metanephric nephron tubule development relationship: BFO:0000050 GO:0072273 ! part of metanephric nephron morphogenesis relationship: RO:0002298 UBERON:0005146 ! results in morphogenesis of metanephric nephron tubule creation_date: 2010-04-01T03:25:11Z [Term] id: GO:0072283 name: metanephric renal vesicle morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the metanephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the metanephric nephron epithelium, and is formed by the condensation of mesenchymal cells." [GOC:mtg_kidney_jan10] is_a: GO:0072077 ! renal vesicle morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0005147 ! results in morphogenesis of metanephric renal vesicle relationship: BFO:0000050 GO:0072273 ! part of metanephric nephron morphogenesis relationship: RO:0002298 UBERON:0005147 ! results in morphogenesis of metanephric renal vesicle creation_date: 2010-04-01T03:28:00Z [Term] id: GO:0072285 name: mesenchymal to epithelial transition involved in metanephric renal vesicle formation namespace: biological_process def: "A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephric renal vesicle." [GOC:mtg_kidney_jan10] is_a: GO:0003337 ! mesenchymal to epithelial transition involved in metanephros morphogenesis is_a: GO:0072036 ! mesenchymal to epithelial transition involved in renal vesicle formation intersection_of: GO:0060231 ! mesenchymal to epithelial transition intersection_of: BFO:0000050 GO:0072093 ! part of metanephric renal vesicle formation relationship: BFO:0000050 GO:0072093 ! part of metanephric renal vesicle formation creation_date: 2010-04-01T03:43:31Z [Term] id: GO:0072289 name: metanephric nephron tubule formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a metanephric nephron tubule from unspecified parts. A metanephric nephron tubule is an epithelial tube that is part of a nephron in the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0072079 ! nephron tubule formation is_a: GO:0072174 ! metanephric tubule formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0005146 ! results in formation of anatomical entity metanephric nephron tubule relationship: BFO:0000050 GO:0072282 ! part of metanephric nephron tubule morphogenesis relationship: RO:0002297 UBERON:0005146 ! results in formation of anatomical entity metanephric nephron tubule creation_date: 2010-04-09T03:47:44Z [Term] id: GO:0072290 name: epithelial cell migration involved in metanephric nephron tubule morphogenesis namespace: biological_process def: "The orderly movement of epithelial cells within a renal tubule that contributes to metanephric nephron tubule morphogenesis." [GOC:mtg_kidney_jan10] is_a: GO:0035788 ! cell migration involved in metanephros development is_a: GO:0072155 ! epithelial cell migration involved in nephron tubule morphogenesis intersection_of: GO:0010631 ! epithelial cell migration intersection_of: BFO:0000050 GO:0072282 ! part of metanephric nephron tubule morphogenesis relationship: BFO:0000050 GO:0072282 ! part of metanephric nephron tubule morphogenesis creation_date: 2010-04-09T03:52:29Z [Term] id: GO:0072304 name: regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis namespace: biological_process def: "Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] synonym: "regulation of mesenchymal stem cell apoptotic process involved in metanephric nephron morphogenesis" EXACT [] is_a: GO:0072039 ! regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis is_a: GO:1900211 ! regulation of mesenchymal cell apoptotic process involved in metanephros development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1901147 ! regulates (processual) mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis relationship: RO:0002211 GO:0072309 ! regulates (processual) mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis relationship: RO:0002211 GO:1901147 ! regulates (processual) mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis creation_date: 2010-04-09T05:03:41Z [Term] id: GO:0072305 name: negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis namespace: biological_process def: "Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] synonym: "negative regulation of mesenchymal stem cell apoptotic process involved in metanephric nephron morphogenesis" EXACT [] is_a: GO:0072040 ! negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis is_a: GO:0072304 ! regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis is_a: GO:1900212 ! negative regulation of mesenchymal cell apoptotic process involved in metanephros development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1901147 ! negatively regulates mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis relationship: RO:0002212 GO:0072309 ! negatively regulates mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis relationship: RO:0002212 GO:1901147 ! negatively regulates mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis creation_date: 2010-04-09T05:03:41Z [Term] id: GO:0072306 name: positive regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis namespace: biological_process def: "Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] synonym: "positive regulation of mesenchymal stem cell apoptotic process involved in metanephric nephron morphogenesis" EXACT [] is_a: GO:0072041 ! positive regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis is_a: GO:0072304 ! regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis is_a: GO:1900213 ! positive regulation of mesenchymal cell apoptotic process involved in metanephros development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1901147 ! positively regulates mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis relationship: RO:0002213 GO:0072309 ! positively regulates mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis relationship: RO:0002213 GO:1901147 ! positively regulates mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis creation_date: 2010-04-09T05:03:41Z [Term] id: GO:0072307 name: regulation of metanephric nephron tubule epithelial cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation." [GOC:mtg_kidney_jan10] is_a: GO:0072182 ! regulation of nephron tubule epithelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0072257 ! regulates (processual) metanephric nephron tubule epithelial cell differentiation relationship: RO:0002211 GO:0072257 ! regulates (processual) metanephric nephron tubule epithelial cell differentiation creation_date: 2010-04-09T05:03:41Z [Term] id: GO:0072308 name: negative regulation of metanephric nephron tubule epithelial cell differentiation namespace: biological_process def: "Any process that decreases the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation." [GOC:mtg_kidney_jan10] is_a: GO:0072183 ! negative regulation of nephron tubule epithelial cell differentiation is_a: GO:0072307 ! regulation of metanephric nephron tubule epithelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0072257 ! negatively regulates metanephric nephron tubule epithelial cell differentiation relationship: RO:0002212 GO:0072257 ! negatively regulates metanephric nephron tubule epithelial cell differentiation creation_date: 2010-04-09T05:03:41Z [Term] id: GO:0072309 name: mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis namespace: biological_process def: "The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the metanephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells." [GOC:mtg_kidney_jan10] is_a: GO:0072038 ! mesenchymal stem cell maintenance involved in nephron morphogenesis relationship: BFO:0000050 GO:0072273 ! part of metanephric nephron morphogenesis creation_date: 2010-04-09T05:03:41Z [Term] id: GO:0072329 name: monocarboxylic acid catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group." [GOC:mah] is_a: GO:0032787 ! monocarboxylic acid metabolic process is_a: GO:0046395 ! carboxylic acid catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:35757 ! has primary input monocarboxylic acid anion relationship: RO:0004009 CHEBI:35757 ! has primary input monocarboxylic acid anion creation_date: 2010-11-02T04:41:55Z [Term] id: GO:0072330 name: monocarboxylic acid biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group." [GOC:mah] synonym: "monocarboxylic acid anabolism" EXACT [GOC:mah] synonym: "monocarboxylic acid biosynthesis" EXACT [GOC:mah] synonym: "monocarboxylic acid formation" EXACT [GOC:mah] synonym: "monocarboxylic acid synthesis" EXACT [GOC:mah] is_a: GO:0032787 ! monocarboxylic acid metabolic process is_a: GO:0046394 ! carboxylic acid biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:35757 ! has primary output monocarboxylic acid anion relationship: RO:0004008 CHEBI:35757 ! has primary output monocarboxylic acid anion creation_date: 2010-11-02T04:51:32Z [Term] id: GO:0072348 name: sulfur compound transport namespace: biological_process def: "The directed movement of compounds that contain sulfur, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] synonym: "sulfur-containing compound transport" EXACT [GOC:mah] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:26835 ! has primary input sulfur molecular entity relationship: RO:0004009 CHEBI:26835 ! has primary input sulfur molecular entity creation_date: 2010-11-11T11:43:56Z [Term] id: GO:0072359 name: circulatory system development namespace: biological_process def: "The process whose specific outcome is the progression of the circulatory system over time, from its formation to the mature structure. The circulatory system is the organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis." [GOC:mah, UBERON:0001009] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001009 ! results in development of circulatory system relationship: RO:0002296 UBERON:0001009 ! results in development of circulatory system creation_date: 2010-11-16T11:27:39Z [Term] id: GO:0072360 name: vascular cord development namespace: biological_process def: "The progression of the vascular cord over time from its initial formation until its mature state. The vascular cord is the primordial vasculature that will develop into blood vessels by the process of tubulogenesis." [GOC:mah, PMID:7084422, ZFA:0005077] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0006965 ! results in development of vascular cord relationship: BFO:0000050 GO:0072359 ! part of circulatory system development relationship: RO:0002296 UBERON:0006965 ! results in development of vascular cord creation_date: 2010-11-16T11:46:55Z [Term] id: GO:0072384 name: organelle transport along microtubule namespace: biological_process def: "The directed movement of an organelle along a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination." [GOC:mah] synonym: "microtubule-based organelle localization" EXACT [GOC:rl] is_a: GO:0010970 ! transport along microtubule is_a: GO:0051656 ! establishment of organelle localization intersection_of: GO:0046907 ! intracellular transport intersection_of: RO:0002341 GO:0005874 ! results in transport along microtubule intersection_of: RO:0004009 GO:0043226 ! has primary input organelle creation_date: 2010-12-01T04:59:11Z [Term] id: GO:0072488 name: ammonium transmembrane transport namespace: biological_process def: "The process in which ammonium is transported across a membrane. Ammonium is the cation NH4+." [GOC:mah] synonym: "ammonium membrane transport" EXACT [] is_a: GO:0071705 ! nitrogen compound transport is_a: GO:0098662 ! inorganic cation transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002342 GO:0016020 ! results in transport across membrane intersection_of: RO:0004009 CHEBI:28938 ! has primary input ammonium relationship: RO:0004009 CHEBI:28938 ! has primary input ammonium creation_date: 2010-12-10T10:29:57Z [Term] id: GO:0072520 name: seminiferous tubule development namespace: biological_process def: "The reproductive developmental process whose specific outcome is the progression of the seminiferous tubule over time, from its formation to the mature structure. Seminiferous tubules are ducts located in the testicles, and are the specific location of meiosis, and the subsequent creation of gametes, namely spermatozoa." [GOC:BHF, GOC:mah, UBERON:0001343] is_a: GO:0035295 ! tube development is_a: GO:0048608 ! reproductive structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001343 ! results in development of seminiferous tubule of testis relationship: BFO:0000050 GO:0008584 ! part of male gonad development relationship: RO:0002296 UBERON:0001343 ! results in development of seminiferous tubule of testis creation_date: 2011-01-04T12:50:36Z [Term] id: GO:0072537 name: fibroblast activation namespace: biological_process def: "A change in the morphology or behavior of a fibroblast resulting from exposure to an activating factor such as a cellular or soluble ligand." [CL:0000057, GOC:BHF, GOC:mah] is_a: GO:0001775 ! cell activation intersection_of: GO:0001775 ! cell activation intersection_of: RO:0004009 CL:0000057 ! has primary input fibroblast relationship: RO:0004009 CL:0000057 ! has primary input fibroblast creation_date: 2011-01-14T04:35:08Z [Term] id: GO:0072560 name: type B pancreatic cell maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for a type B pancreatic cell to attain its fully functional state. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin." [CL:0000169, GOC:BHF] synonym: "pancreatic B cell maturation" EXACT [CL:0000169, GOC:mah] synonym: "pancreatic beta cell maturation" EXACT [CL:0000169, GOC:mah] is_a: GO:0002071 ! glandular epithelial cell maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 CL:0000169 ! results in maturation of type B pancreatic cell relationship: BFO:0000050 GO:0003323 ! part of type B pancreatic cell development relationship: RO:0002299 CL:0000169 ! results in maturation of type B pancreatic cell creation_date: 2011-01-27T01:57:14Z [Term] id: GO:0072575 name: epithelial cell proliferation involved in liver morphogenesis namespace: biological_process def: "The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the liver." [GOC:BHF, GOC:mah] is_a: GO:0050673 ! epithelial cell proliferation intersection_of: GO:0050673 ! epithelial cell proliferation intersection_of: BFO:0000050 GO:0072576 ! part of liver morphogenesis relationship: BFO:0000050 GO:0072576 ! part of liver morphogenesis creation_date: 2011-02-02T03:37:50Z [Term] id: GO:0072576 name: liver morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the liver are generated and organized." [GOC:mah] is_a: GO:0022612 ! gland morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002107 ! results in morphogenesis of liver relationship: BFO:0000050 GO:0001889 ! part of liver development relationship: RO:0002298 UBERON:0002107 ! results in morphogenesis of liver creation_date: 2011-02-02T03:41:30Z [Term] id: GO:0072577 name: endothelial cell apoptotic process namespace: biological_process def: "Any apoptotic process in an endothelial cell. An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal." [CL:0000115, GOC:BHF, GOC:mah, GOC:mtg_apoptosis] synonym: "apoptosis of endothelial cells" EXACT [GOC:mah] synonym: "endothelial cell programmed cell death by apoptosis" EXACT [GOC:mah] synonym: "killing of endothelial cells" EXACT [GOC:mah] synonym: "programmed cell death of endothelial cells by apoptosis" EXACT [GOC:mah] synonym: "programmed cell death, endothelial cells" EXACT [GOC:mah] is_a: GO:1904019 ! epithelial cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000115 ! occurs in endothelial cell relationship: BFO:0000066 CL:0000115 ! occurs in endothelial cell creation_date: 2011-02-02T03:56:24Z [Term] id: GO:0072592 name: oxygen metabolic process namespace: biological_process def: "The chemical reactions and pathways involving diatomic oxygen (O2)." [GOC:mah] synonym: "diatomic oxygen metabolic process" EXACT [CHEBI:33263] synonym: "oxygen metabolism" EXACT [GOC:mah] is_a: GO:0044237 ! cellular metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:15379 ! has primary input or output dioxygen relationship: RO:0004007 CHEBI:15379 ! has primary input or output dioxygen creation_date: 2011-02-11T10:46:51Z [Term] id: GO:0072594 name: establishment of protein localization to organelle namespace: biological_process def: "The directed movement of a protein to a specific location on or in an organelle. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle." [GOC:mah] synonym: "establishment of protein localisation to organelle" EXACT [GOC:mah] is_a: GO:0045184 ! establishment of protein localization intersection_of: GO:0045184 ! establishment of protein localization intersection_of: RO:0002339 GO:0043226 ! has target end location organelle relationship: RO:0002339 GO:0043226 ! has target end location organelle creation_date: 2011-02-14T01:56:51Z [Term] id: GO:0072657 name: protein localization to membrane namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a specific location in a membrane." [GOC:mah] synonym: "protein localisation in membrane" EXACT [GOC:mah] synonym: "protein localization in membrane" EXACT [] is_a: GO:0008104 ! protein localization is_a: GO:0051668 ! localization within membrane intersection_of: GO:0008104 ! protein localization intersection_of: RO:0002339 GO:0016020 ! has target end location membrane creation_date: 2011-02-14T02:35:18Z [Term] id: GO:0072659 name: protein localization to plasma membrane namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane." [GOC:mah] is_a: GO:0072657 ! protein localization to membrane is_a: GO:1990778 ! protein localization to cell periphery intersection_of: GO:0008104 ! protein localization intersection_of: RO:0002338 GO:0005622 ! has target start location intracellular anatomical structure intersection_of: RO:0002339 GO:0005886 ! has target end location plasma membrane relationship: RO:0002338 GO:0005622 ! has target start location intracellular anatomical structure relationship: RO:0002339 GO:0005886 ! has target end location plasma membrane creation_date: 2009-07-10T10:29:23Z [Term] id: GO:0072665 name: protein localization to vacuole namespace: biological_process def: "A process in which a protein is transported to, or maintained at, a location in a vacuole." [GOC:ecd] synonym: "protein localisation to vacuole" EXACT [GOC:mah] is_a: GO:0033365 ! protein localization to organelle intersection_of: GO:0008104 ! protein localization intersection_of: RO:0002339 GO:0005773 ! has target end location vacuole relationship: RO:0002339 GO:0005773 ! has target end location vacuole creation_date: 2011-02-14T02:55:35Z [Term] id: GO:0072666 name: establishment of protein localization to vacuole namespace: biological_process def: "The directed movement of a protein to a specific location in a vacuole." [GOC:mah] synonym: "establishment of protein localisation to vacuole" EXACT [GOC:mah] is_a: GO:0072594 ! establishment of protein localization to organelle intersection_of: GO:0045184 ! establishment of protein localization intersection_of: RO:0002339 GO:0005773 ! has target end location vacuole relationship: RO:0002339 GO:0005773 ! has target end location vacuole creation_date: 2011-02-14T02:56:29Z [Term] id: GO:0072676 name: lymphocyte migration namespace: biological_process def: "The movement of a lymphocyte within or between different tissues and organs of the body." [CL:0000542, GOC:BHF, GOC:mah] is_a: GO:0071674 ! mononuclear cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000542 ! results in movement of lymphocyte relationship: RO:0002565 CL:0000542 ! results in movement of lymphocyte creation_date: 2011-02-22T03:38:12Z [Term] id: GO:0072678 name: T cell migration namespace: biological_process def: "The movement of a T cell within or between different tissues and organs of the body." [CL:0000084, GOC:BHF, GOC:mah] synonym: "T lymphocyte migration" EXACT [CL:0000084] synonym: "T-cell migration" EXACT [CL:0000084] synonym: "T-lymphocyte migration" EXACT [CL:0000084] is_a: GO:0072676 ! lymphocyte migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000084 ! results in movement of T cell relationship: RO:0002565 CL:0000084 ! results in movement of T cell creation_date: 2011-02-22T03:40:40Z [Term] id: GO:0072697 name: protein localization to cell cortex namespace: biological_process def: "A process in which a protein is transported to, or maintained in, the cell cortex." [GOC:mah] synonym: "protein localisation to cell cortex" EXACT [GOC:mah] is_a: GO:1990778 ! protein localization to cell periphery intersection_of: GO:0008104 ! protein localization intersection_of: RO:0002339 GO:0005938 ! has target end location cell cortex relationship: RO:0002339 GO:0005938 ! has target end location cell cortex creation_date: 2012-04-11T01:16:33Z [Term] id: GO:0072698 name: protein localization to microtubule cytoskeleton namespace: biological_process def: "A cellular protein localization process in which a protein is transported to, or maintained at, a location within the microtubule cytoskeleton." [GOC:mah] synonym: "protein localisation to microtubule cytoskeleton" EXACT [GOC:mah] is_a: GO:0044380 ! protein localization to cytoskeleton intersection_of: GO:0008104 ! protein localization intersection_of: RO:0002339 GO:0015630 ! has target end location microtubule cytoskeleton relationship: RO:0002339 GO:0015630 ! has target end location microtubule cytoskeleton creation_date: 2012-04-11T01:19:35Z [Term] id: GO:0080090 name: regulation of primary metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism." [PMID:19211694] is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0044238 ! regulates (processual) primary metabolic process relationship: RO:0002211 GO:0044238 ! regulates (processual) primary metabolic process creation_date: 2009-04-22T04:30:52Z [Term] id: GO:0080134 name: regulation of response to stress namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." [GOC:dhl] is_a: GO:0048583 ! regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006950 ! regulates (processual) response to stress relationship: RO:0002211 GO:0006950 ! regulates (processual) response to stress creation_date: 2009-05-06T04:51:28Z [Term] id: GO:0080154 name: regulation of fertilization namespace: biological_process def: "Any process that modulates the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy)." [GOC:DHL, PMID:20478994] is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0009566 ! regulates (processual) fertilization relationship: RO:0002211 GO:0009566 ! regulates (processual) fertilization creation_date: 2010-09-01T03:44:27Z [Term] id: GO:0085029 name: extracellular matrix assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of the extracellular matrix." [GOC:jl] is_a: GO:0022607 ! cellular component assembly is_a: GO:0030198 ! extracellular matrix organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0031012 ! results in assembly of extracellular matrix relationship: RO:0002588 GO:0031012 ! results in assembly of extracellular matrix creation_date: 2010-07-14T12:52:49Z [Term] id: GO:0086001 name: cardiac muscle cell action potential namespace: biological_process def: "An action potential that occurs in a cardiac muscle cell." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] is_a: GO:0001508 ! action potential intersection_of: GO:0001508 ! action potential intersection_of: BFO:0000066 CL:0000746 ! occurs in cardiac muscle cell relationship: BFO:0000066 CL:0000746 ! occurs in cardiac muscle cell creation_date: 2011-11-10T07:45:11Z [Term] id: GO:0086015 name: SA node cell action potential namespace: biological_process def: "An action potential that occurs in a sinoatrial node cardiac muscle cell." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "SA node cardiac muscle cell action potential" EXACT [] synonym: "SAN cardiac muscle cell action potential" EXACT [] synonym: "sinoatrial node cardiac muscle cell action potential" EXACT [] is_a: GO:0086001 ! cardiac muscle cell action potential intersection_of: GO:0001508 ! action potential intersection_of: BFO:0000066 CL:1000409 ! occurs in myocyte of sinoatrial node relationship: BFO:0000050 GO:0086018 ! part of SA node cell to atrial cardiac muscle cell signaling relationship: BFO:0000066 CL:1000409 ! occurs in myocyte of sinoatrial node creation_date: 2011-11-10T08:50:15Z [Term] id: GO:0086016 name: AV node cell action potential namespace: biological_process def: "An action potential that occurs in an atrioventricular node cardiac muscle cell." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "atrioventricular node cardiac muscle cell action potential" EXACT [] synonym: "AV node cardiac muscle cell action potential" EXACT [] is_a: GO:0086001 ! cardiac muscle cell action potential intersection_of: GO:0001508 ! action potential intersection_of: BFO:0000066 CL:1000410 ! occurs in myocyte of atrioventricular node relationship: BFO:0000050 GO:0086027 ! part of AV node cell to bundle of His cell signaling relationship: BFO:0000066 CL:1000410 ! occurs in myocyte of atrioventricular node creation_date: 2011-11-10T08:58:56Z [Term] id: GO:0086017 name: Purkinje myocyte action potential namespace: biological_process def: "An action potential that occurs in a Purkinje myocyte." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] is_a: GO:0086001 ! cardiac muscle cell action potential intersection_of: GO:0001508 ! action potential intersection_of: BFO:0000066 CL:0002068 ! occurs in Purkinje myocyte relationship: BFO:0000050 GO:0086029 ! part of Purkinje myocyte to ventricular cardiac muscle cell signaling relationship: BFO:0000066 CL:0002068 ! occurs in Purkinje myocyte creation_date: 2011-11-10T08:58:56Z [Term] id: GO:0086018 name: SA node cell to atrial cardiac muscle cell signaling namespace: biological_process def: "Any process that mediates the transfer of information from an SA node cardiomyocyte to an atrial cardiomyocyte." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "SA node cardiac muscle cell to atrial cardiac muscle cell signalling" EXACT [] synonym: "SA node cardiomyocyte to atrial cardiomyocyte signalling" EXACT [] synonym: "SAN cardiomyocyte to atrial cardiomyocyte signalling" EXACT [] synonym: "sinoatrial node cardiomyocyte to atrial cardiomyocyte signalling" EXACT [] is_a: GO:0086019 ! cell-cell signaling involved in cardiac conduction is_a: GO:0086070 ! SA node cell to atrial cardiac muscle cell communication creation_date: 2011-11-10T09:15:01Z [Term] id: GO:0086019 name: cell-cell signaling involved in cardiac conduction namespace: biological_process def: "Any process that mediates the transfer of information from one cell to another and contributes to the heart process that regulates cardiac muscle contraction; beginning with the generation of an action potential in the sinoatrial node and ending with regulation of contraction of the myocardium." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "cell-cell signalling involved in cardiac conduction" EXACT [GOC:mah] is_a: GO:0007267 ! cell-cell signaling is_a: GO:0086065 ! cell communication involved in cardiac conduction intersection_of: GO:0007267 ! cell-cell signaling intersection_of: BFO:0000050 GO:0061337 ! part of cardiac conduction creation_date: 2011-11-16T03:43:52Z [Term] id: GO:0086027 name: AV node cell to bundle of His cell signaling namespace: biological_process def: "Any process that mediates the transfer of information from an AV node cardiac muscle cell to a bundle of His cardiomyocyte." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "atrioventricular node to bundle of His cell signaling" EXACT [] synonym: "AV node cell to bundle of His cell signalling" EXACT [GOC:mah] is_a: GO:0086019 ! cell-cell signaling involved in cardiac conduction is_a: GO:0086067 ! AV node cell to bundle of His cell communication creation_date: 2011-11-11T02:02:14Z [Term] id: GO:0086029 name: Purkinje myocyte to ventricular cardiac muscle cell signaling namespace: biological_process def: "Any process that mediates the transfer of information from a Purkinje myocyte to a ventricular cardiac muscle cell." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "Purkinje myocyte to ventricular cardiac muscle cell signalling" EXACT [GOC:mah] is_a: GO:0086019 ! cell-cell signaling involved in cardiac conduction is_a: GO:0086068 ! Purkinje myocyte to ventricular cardiac muscle cell communication intersection_of: GO:0007267 ! cell-cell signaling intersection_of: RO:0002231 CL:0002068 ! has start location Purkinje myocyte intersection_of: RO:0002232 CL:2000046 ! has end location ventricular cardiac muscle cell relationship: RO:0002231 CL:0002068 ! has start location Purkinje myocyte relationship: RO:0002232 CL:2000046 ! has end location ventricular cardiac muscle cell creation_date: 2011-11-11T02:02:14Z [Term] id: GO:0086065 name: cell communication involved in cardiac conduction namespace: biological_process def: "Any process that mediates interactions between a cell and its surroundings that contributes to the process of cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] is_a: GO:0007154 ! cell communication intersection_of: GO:0007154 ! cell communication intersection_of: BFO:0000050 GO:0061337 ! part of cardiac conduction relationship: BFO:0000050 GO:0061337 ! part of cardiac conduction creation_date: 2011-11-22T08:57:02Z [Term] id: GO:0086067 name: AV node cell to bundle of His cell communication namespace: biological_process def: "The process that mediates interactions between an AV node cell and its surroundings that contributes to the process of the AV node cell communicating with a bundle of His cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "atrioventricular node cell to bundle of His cell communication" EXACT [] is_a: GO:0086065 ! cell communication involved in cardiac conduction creation_date: 2011-11-22T09:11:44Z [Term] id: GO:0086068 name: Purkinje myocyte to ventricular cardiac muscle cell communication namespace: biological_process def: "The process that mediates interactions between a Purkinje myocyte and its surroundings that contributes to the process of the Purkinje myocyte communicating with a ventricular cardiac muscle cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] is_a: GO:0086065 ! cell communication involved in cardiac conduction creation_date: 2011-11-22T09:14:49Z [Term] id: GO:0086070 name: SA node cell to atrial cardiac muscle cell communication namespace: biological_process def: "The process that mediates interactions between an SA node cardiomyocyte and its surroundings that contributes to the process of the SA node cardiomyocyte communicating with an atrial cardiomyocyte in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "SA node cardiac muscle cell to atrial cardiac muscle cell communication" EXACT [] synonym: "SA node cardiomyocyte to atrial cardiomyocyte communication" EXACT [] synonym: "SAN cardiomyocyte to atrial cardiomyocyte communication" EXACT [] synonym: "sinoatrial node cardiomyocyte to atrial cardiomyocyte communication" EXACT [] is_a: GO:0086065 ! cell communication involved in cardiac conduction creation_date: 2011-11-22T09:32:45Z [Term] id: GO:0090009 name: primitive streak formation namespace: biological_process def: "The developmental process pertaining to the initial formation of the primitive streak from unspecified parts. The primitive streak is a ridge of cells running along the midline of the embryo where the mesoderm ingresses. It defines the anterior-posterior axis." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0004341 ! results in formation of anatomical entity primitive streak relationship: BFO:0000050 GO:0001702 ! part of gastrulation with mouth forming second relationship: BFO:0000050 GO:0009948 ! part of anterior/posterior axis specification relationship: RO:0002297 UBERON:0004341 ! results in formation of anatomical entity primitive streak creation_date: 2009-07-29T10:31:31Z [Term] id: GO:0090063 name: positive regulation of microtubule nucleation namespace: biological_process def: "Any process that increases the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell." [GOC:dph, GOC:tb] is_a: GO:0010968 ! regulation of microtubule nucleation is_a: GO:0031116 ! positive regulation of microtubule polymerization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007020 ! positively regulates microtubule nucleation relationship: RO:0002213 GO:0007020 ! positively regulates microtubule nucleation creation_date: 2009-08-12T11:33:09Z [Term] id: GO:0090068 name: positive regulation of cell cycle process namespace: biological_process def: "Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events." [GOC:dph, GOC:tb] is_a: GO:0010564 ! regulation of cell cycle process is_a: GO:0045787 ! positive regulation of cell cycle intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0022402 ! positively regulates cell cycle process relationship: RO:0002213 GO:0022402 ! positively regulates cell cycle process creation_date: 2009-09-09T11:39:52Z [Term] id: GO:0090069 name: regulation of ribosome biogenesis namespace: biological_process def: "Any process that modulates the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits." [GOC:dph, GOC:tb] is_a: GO:0044087 ! regulation of cellular component biogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0042254 ! regulates (processual) ribosome biogenesis relationship: RO:0002211 GO:0042254 ! regulates (processual) ribosome biogenesis creation_date: 2009-09-11T10:32:17Z [Term] id: GO:0090070 name: positive regulation of ribosome biogenesis namespace: biological_process def: "Any process that increases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits." [GOC:dph, GOC:tb] is_a: GO:0044089 ! positive regulation of cellular component biogenesis is_a: GO:0090069 ! regulation of ribosome biogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0042254 ! positively regulates ribosome biogenesis relationship: RO:0002213 GO:0042254 ! positively regulates ribosome biogenesis creation_date: 2009-09-11T10:32:17Z [Term] id: GO:0090071 name: negative regulation of ribosome biogenesis namespace: biological_process def: "Any process that decreases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits." [GOC:dph, GOC:tb] is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:0090069 ! regulation of ribosome biogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0042254 ! negatively regulates ribosome biogenesis relationship: RO:0002212 GO:0042254 ! negatively regulates ribosome biogenesis creation_date: 2009-09-11T10:32:17Z [Term] id: GO:0090087 name: regulation of peptide transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:tb] is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0015833 ! regulates (processual) peptide transport relationship: RO:0002211 GO:0015833 ! regulates (processual) peptide transport creation_date: 2009-10-23T11:21:38Z [Term] id: GO:0090091 name: positive regulation of extracellular matrix disassembly namespace: biological_process def: "Any process that increases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix." [GOC:dph, GOC:tb] is_a: GO:0010715 ! regulation of extracellular matrix disassembly is_a: GO:1903055 ! positive regulation of extracellular matrix organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0022617 ! positively regulates extracellular matrix disassembly relationship: RO:0002213 GO:0022617 ! positively regulates extracellular matrix disassembly creation_date: 2009-11-04T10:03:25Z [Term] id: GO:0090130 name: tissue migration namespace: biological_process def: "The process in which the population of cells that make up a tissue undergo directed movement." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0032501 ! multicellular organismal process creation_date: 2009-12-07T03:13:55Z [Term] id: GO:0090132 name: epithelium migration namespace: biological_process def: "The process in which the population of cells that make up an epithelium undergo directed movement." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0090130 ! tissue migration creation_date: 2009-12-07T03:19:34Z [Term] id: GO:0090138 name: regulation of actin cytoskeleton organization by cell-cell adhesion namespace: biological_process def: "Any cell-cell adhesion process that modulates the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins." [GOC:ascb_2009, GOC:dph, GOC:tb] synonym: "regulation of actin cytoskeleton organisation by cell-cell adhesion" EXACT [GOC:mah] is_a: GO:0032956 ! regulation of actin cytoskeleton organization is_a: GO:0098609 ! cell-cell adhesion intersection_of: GO:0098609 ! cell-cell adhesion intersection_of: RO:0002211 GO:0030036 ! regulates (processual) actin cytoskeleton organization creation_date: 2009-12-08T02:05:00Z [Term] id: GO:0090150 name: establishment of protein localization to membrane namespace: biological_process def: "The directed movement of a protein to a specific location in a membrane." [GOC:ascb_2009, GOC:dph, GOC:tb] synonym: "establishment of protein localisation in membrane" EXACT [GOC:mah] synonym: "establishment of protein localization in membrane" EXACT [] is_a: GO:0045184 ! establishment of protein localization is_a: GO:0051668 ! localization within membrane intersection_of: GO:0045184 ! establishment of protein localization intersection_of: RO:0002339 GO:0016020 ! has target end location membrane creation_date: 2009-12-08T03:18:51Z [Term] id: GO:0090162 name: establishment of epithelial cell polarity namespace: biological_process def: "The specification and formation of anisotropic intracellular organization of an epithelial cell." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0030010 ! establishment of cell polarity intersection_of: GO:0030010 ! establishment of cell polarity intersection_of: BFO:0000066 CL:0000066 ! occurs in epithelial cell relationship: BFO:0000066 CL:0000066 ! occurs in epithelial cell creation_date: 2009-12-08T08:58:27Z [Term] id: GO:0090166 name: Golgi disassembly namespace: biological_process def: "A cellular process that results in the breakdown of a Golgi apparatus that contributes to Golgi inheritance." [GOC:ascb_2009, GOC:dph, GOC:tb] synonym: "Golgi apparatus disassembly" EXACT [] is_a: GO:0007030 ! Golgi organization is_a: GO:1903008 ! organelle disassembly intersection_of: GO:0022411 ! cellular component disassembly intersection_of: RO:0002590 GO:0005794 ! results in disassembly of Golgi apparatus relationship: BFO:0000050 GO:0048313 ! part of Golgi inheritance relationship: RO:0002590 GO:0005794 ! results in disassembly of Golgi apparatus creation_date: 2009-12-08T09:15:11Z [Term] id: GO:0090168 name: Golgi reassembly namespace: biological_process def: "The reformation of the Golgi following its breakdown and partitioning contributing to Golgi inheritance." [GOC:ascb_2009, GOC:dph, GOC:tb] synonym: "Golgi apparatus reassembly" EXACT [] is_a: GO:0007030 ! Golgi organization is_a: GO:0022607 ! cellular component assembly relationship: BFO:0000050 GO:0048313 ! part of Golgi inheritance creation_date: 2009-12-08T09:15:11Z [Term] id: GO:0090170 name: regulation of Golgi inheritance namespace: biological_process def: "Any process that modulates the rate, frequency or extent of Golgi inheritance. Golgi inheritance is the partitioning of Golgi apparatus between daughter cells at cell division." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:1903358 ! regulation of Golgi organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048313 ! regulates (processual) Golgi inheritance relationship: RO:0002211 GO:0048313 ! regulates (processual) Golgi inheritance creation_date: 2009-12-11T10:21:59Z [Term] id: GO:0090171 name: chondrocyte morphogenesis namespace: biological_process def: "The process in which the structures of a chondrocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a chondrocyte." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0000902 ! cell morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002299 CL:0000138 ! results in maturation of chondrocyte relationship: BFO:0000050 GO:0002063 ! part of chondrocyte development relationship: RO:0002299 CL:0000138 ! results in maturation of chondrocyte creation_date: 2009-12-11T10:36:02Z [Term] id: GO:0090174 name: organelle membrane fusion namespace: biological_process def: "The joining of two lipid bilayers to form a single organelle membrane." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0048284 ! organelle fusion is_a: GO:0061025 ! membrane fusion intersection_of: GO:0061025 ! membrane fusion intersection_of: RO:0012008 GO:0031090 ! results in fusion of organelle membrane relationship: RO:0012008 GO:0031090 ! results in fusion of organelle membrane creation_date: 2009-12-11T11:44:58Z [Term] id: GO:0090183 name: regulation of kidney development namespace: biological_process def: "Any process that modulates the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:dph, GOC:tb, GOC:yaf] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001822 ! regulates (processual) kidney development relationship: RO:0002211 GO:0001822 ! regulates (processual) kidney development creation_date: 2009-12-18T10:50:56Z [Term] id: GO:0090184 name: positive regulation of kidney development namespace: biological_process def: "Any process that increases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:dph, GOC:tb, GOC:yaf] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:0090183 ! regulation of kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001822 ! positively regulates kidney development relationship: RO:0002213 GO:0001822 ! positively regulates kidney development creation_date: 2009-12-18T10:52:01Z [Term] id: GO:0090185 name: negative regulation of kidney development namespace: biological_process def: "Any process that decreases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:dph, GOC:tb, GOC:yaf] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:0090183 ! regulation of kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001822 ! negatively regulates kidney development relationship: RO:0002212 GO:0001822 ! negatively regulates kidney development creation_date: 2009-12-18T10:58:45Z [Term] id: GO:0090189 name: regulation of branching involved in ureteric bud morphogenesis namespace: biological_process def: "Any process that modulates the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules." [GOC:dph, GOC:tb, GOC:yaf] is_a: GO:0060688 ! regulation of morphogenesis of a branching structure is_a: GO:0090183 ! regulation of kidney development is_a: GO:1905330 ! regulation of morphogenesis of an epithelium is_a: GO:2000027 ! regulation of animal organ morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001658 ! regulates (processual) branching involved in ureteric bud morphogenesis relationship: RO:0002211 GO:0001658 ! regulates (processual) branching involved in ureteric bud morphogenesis creation_date: 2009-12-18T11:11:17Z [Term] id: GO:0090190 name: positive regulation of branching involved in ureteric bud morphogenesis namespace: biological_process def: "Any process that increases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules." [GOC:dph, GOC:tb, GOC:yaf] is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:0090189 ! regulation of branching involved in ureteric bud morphogenesis is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001658 ! positively regulates branching involved in ureteric bud morphogenesis relationship: RO:0002213 GO:0001658 ! positively regulates branching involved in ureteric bud morphogenesis creation_date: 2009-12-18T11:11:17Z [Term] id: GO:0090191 name: negative regulation of branching involved in ureteric bud morphogenesis namespace: biological_process def: "Any process that decreases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules." [GOC:dph, GOC:tb, GOC:yaf] is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:0090189 ! regulation of branching involved in ureteric bud morphogenesis is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001658 ! negatively regulates branching involved in ureteric bud morphogenesis relationship: RO:0002212 GO:0001658 ! negatively regulates branching involved in ureteric bud morphogenesis creation_date: 2009-12-18T11:11:17Z [Term] id: GO:0090257 name: regulation of muscle system process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a muscle system process, a multicellular organismal process carried out by any of the organs or tissues in a muscle system." [GOC:dph, GOC:tb] is_a: GO:0044057 ! regulation of system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003012 ! regulates (processual) muscle system process relationship: RO:0002211 GO:0003012 ! regulates (processual) muscle system process creation_date: 2010-02-03T11:48:13Z [Term] id: GO:0090273 name: regulation of somatostatin secretion namespace: biological_process def: "Any process that modulates the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas." [GOC:BHF] is_a: GO:0090276 ! regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0070253 ! regulates (processual) somatostatin secretion relationship: RO:0002211 GO:0070253 ! regulates (processual) somatostatin secretion creation_date: 2010-02-05T02:54:14Z [Term] id: GO:0090274 name: positive regulation of somatostatin secretion namespace: biological_process def: "Any process that increases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas." [GOC:BHF] is_a: GO:0090273 ! regulation of somatostatin secretion is_a: GO:0090277 ! positive regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0070253 ! positively regulates somatostatin secretion relationship: RO:0002213 GO:0070253 ! positively regulates somatostatin secretion creation_date: 2010-02-05T02:54:14Z [Term] id: GO:0090275 name: negative regulation of somatostatin secretion namespace: biological_process def: "Any process that decreases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas." [GOC:BHF] is_a: GO:0090273 ! regulation of somatostatin secretion is_a: GO:0090278 ! negative regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0070253 ! negatively regulates somatostatin secretion relationship: RO:0002212 GO:0070253 ! negatively regulates somatostatin secretion creation_date: 2010-02-05T02:54:14Z [Term] id: GO:0090276 name: regulation of peptide hormone secretion namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules." [GOC:tb] is_a: GO:0002791 ! regulation of peptide secretion is_a: GO:0046883 ! regulation of hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030072 ! regulates (processual) peptide hormone secretion relationship: RO:0002211 GO:0030072 ! regulates (processual) peptide hormone secretion creation_date: 2010-02-05T02:56:39Z [Term] id: GO:0090277 name: positive regulation of peptide hormone secretion namespace: biological_process def: "Any process that increases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules." [GOC:tb] is_a: GO:0002793 ! positive regulation of peptide secretion is_a: GO:0046887 ! positive regulation of hormone secretion is_a: GO:0090276 ! regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030072 ! positively regulates peptide hormone secretion relationship: RO:0002213 GO:0030072 ! positively regulates peptide hormone secretion creation_date: 2010-02-05T02:56:39Z [Term] id: GO:0090278 name: negative regulation of peptide hormone secretion namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules." [GOC:tb] is_a: GO:0002792 ! negative regulation of peptide secretion is_a: GO:0046888 ! negative regulation of hormone secretion is_a: GO:0090276 ! regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030072 ! negatively regulates peptide hormone secretion relationship: RO:0002212 GO:0030072 ! negatively regulates peptide hormone secretion creation_date: 2010-02-05T02:56:39Z [Term] id: GO:0090299 name: regulation of neural crest formation namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds." [GOC:tb] is_a: GO:0010717 ! regulation of epithelial to mesenchymal transition is_a: GO:0022603 ! regulation of anatomical structure morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0014029 ! regulates (processual) neural crest formation relationship: RO:0002211 GO:0014029 ! regulates (processual) neural crest formation creation_date: 2010-03-12T04:08:26Z [Term] id: GO:0090300 name: positive regulation of neural crest formation namespace: biological_process def: "Any process that increases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes." [GOC:tb] is_a: GO:0010718 ! positive regulation of epithelial to mesenchymal transition is_a: GO:0090299 ! regulation of neural crest formation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0014029 ! positively regulates neural crest formation relationship: RO:0002213 GO:0014029 ! positively regulates neural crest formation creation_date: 2010-03-12T04:08:26Z [Term] id: GO:0090301 name: negative regulation of neural crest formation namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes." [GOC:tb] is_a: GO:0010719 ! negative regulation of epithelial to mesenchymal transition is_a: GO:0090299 ! regulation of neural crest formation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0014029 ! negatively regulates neural crest formation relationship: RO:0002212 GO:0014029 ! negatively regulates neural crest formation creation_date: 2010-03-12T04:08:26Z [Term] id: GO:0090304 name: nucleic acid metabolic process namespace: biological_process def: "Any cellular metabolic process involving nucleic acids." [GOC:dph, GOC:tb] is_a: GO:0006139 ! nucleobase-containing compound metabolic process is_a: GO:0043170 ! macromolecule metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:33696 ! has primary input or output nucleic acid relationship: RO:0004007 CHEBI:33696 ! has primary input or output nucleic acid creation_date: 2010-04-07T10:18:47Z [Term] id: GO:0090316 name: positive regulation of intracellular protein transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells." [GOC:tb] is_a: GO:0032388 ! positive regulation of intracellular transport is_a: GO:0033157 ! regulation of intracellular protein transport is_a: GO:0051222 ! positive regulation of protein transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006886 ! positively regulates intracellular protein transport relationship: RO:0002213 GO:0006886 ! positively regulates intracellular protein transport creation_date: 2010-04-16T03:45:07Z [Term] id: GO:0090317 name: negative regulation of intracellular protein transport namespace: biological_process def: "Any process that decreases the frequency, rate or extent of the directed movement of proteins within cells." [GOC:tb] is_a: GO:0032387 ! negative regulation of intracellular transport is_a: GO:0033157 ! regulation of intracellular protein transport is_a: GO:0051224 ! negative regulation of protein transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006886 ! negatively regulates intracellular protein transport relationship: RO:0002212 GO:0006886 ! negatively regulates intracellular protein transport creation_date: 2010-04-16T03:45:07Z [Term] id: GO:0090325 name: regulation of locomotion involved in locomotory behavior namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement." [GOC:dph, GOC:kmv, GOC:tb] is_a: GO:0040012 ! regulation of locomotion is_a: GO:0050795 ! regulation of behavior intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0031987 ! regulates (processual) locomotion involved in locomotory behavior relationship: RO:0002211 GO:0031987 ! regulates (processual) locomotion involved in locomotory behavior creation_date: 2010-05-14T10:24:29Z [Term] id: GO:0090326 name: positive regulation of locomotion involved in locomotory behavior namespace: biological_process def: "Any process that increases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement." [GOC:dph, GOC:kmv, GOC:tb] is_a: GO:0040017 ! positive regulation of locomotion is_a: GO:0048520 ! positive regulation of behavior is_a: GO:0090325 ! regulation of locomotion involved in locomotory behavior intersection_of: GO:0050789 ! regulation of biological process intersection_of: RO:0002213 GO:0031987 ! positively regulates locomotion involved in locomotory behavior relationship: RO:0002213 GO:0031987 ! positively regulates locomotion involved in locomotory behavior creation_date: 2010-05-14T10:26:58Z [Term] id: GO:0090327 name: negative regulation of locomotion involved in locomotory behavior namespace: biological_process def: "Any process that decreases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement." [GOC:dph, GOC:kmv, GOC:tb] is_a: GO:0040013 ! negative regulation of locomotion is_a: GO:0048521 ! negative regulation of behavior is_a: GO:0090325 ! regulation of locomotion involved in locomotory behavior intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0031987 ! negatively regulates locomotion involved in locomotory behavior relationship: RO:0002212 GO:0031987 ! negatively regulates locomotion involved in locomotory behavior creation_date: 2010-05-14T10:26:58Z [Term] id: GO:0090425 name: acinar cell differentiation namespace: biological_process def: "The epithelial cell differentiation process in which a relatively unspecialized cell acquires specialized features of an acinar cell, a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini." [GOC:dph, GOC:tb] is_a: GO:0002067 ! glandular epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000622 ! results in acquisition of features of acinar cell relationship: RO:0002315 CL:0000622 ! results in acquisition of features of acinar cell creation_date: 2012-05-04T09:24:48Z [Term] id: GO:0090435 name: protein localization to nuclear envelope namespace: biological_process def: "A process in which a protein is transported to, or maintained at, a location within a nuclear envelope." [GOC:tb] synonym: "protein localization in nuclear envelope" EXACT [] is_a: GO:0034504 ! protein localization to nucleus intersection_of: GO:0008104 ! protein localization intersection_of: RO:0002339 GO:0005635 ! has target end location nuclear envelope relationship: RO:0002339 GO:0005635 ! has target end location nuclear envelope creation_date: 2012-07-30T01:50:41Z [Term] id: GO:0090493 name: catecholamine uptake namespace: biological_process def: "The directed movement of catecholamine into a cell." [GOC:dph, GOC:tb] is_a: GO:0051937 ! catecholamine transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002338 GO:0005576 ! has target start location extracellular region intersection_of: RO:0002339 GO:0005622 ! has target end location intracellular anatomical structure intersection_of: RO:0004009 CHEBI:33567 ! has primary input catecholamine relationship: RO:0002338 GO:0005576 ! has target start location extracellular region relationship: RO:0002339 GO:0005622 ! has target end location intracellular anatomical structure creation_date: 2012-10-17T11:06:17Z [Term] id: GO:0090497 name: mesenchymal cell migration namespace: biological_process def: "The orderly movement of a mesenchymal cell from one site to another, often during the development of a multicellular organism." [GOC:dph, GOC:tb] is_a: GO:0001667 ! ameboidal-type cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0008019 ! results in movement of mesenchymal cell relationship: RO:0002565 CL:0008019 ! results in movement of mesenchymal cell creation_date: 2012-10-17T12:08:17Z [Term] id: GO:0090596 name: sensory organ morphogenesis namespace: biological_process def: "Morphogenesis of a sensory organ. A sensory organ is defined as a tissue or set of tissues that work together to receive and transmit signals from external or internal stimuli. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." [GOC:kmv, ISBN:978-0199210893] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000020 ! results in morphogenesis of sense organ relationship: BFO:0000050 GO:0007423 ! part of sensory organ development relationship: RO:0002298 UBERON:0000020 ! results in morphogenesis of sense organ creation_date: 2014-08-22T13:23:20Z [Term] id: GO:0090598 name: male anatomical structure morphogenesis namespace: biological_process def: "The processes by which anatomical structures that are only present in the male organism are generated and organized." [GOC:kmv, GOC:tb] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0014403 ! results in morphogenesis of male anatomical structure relationship: BFO:0000050 GO:0046661 ! part of male sex differentiation relationship: RO:0002298 UBERON:0014403 ! results in morphogenesis of male anatomical structure creation_date: 2014-08-22T13:29:45Z [Term] id: GO:0090685 name: RNA localization to nucleus namespace: biological_process def: "A macromolecular localization process in which RNA is transported to and maintained in a location within the nucleus." [GOC:mah, PMID:26305931] synonym: "RNA localisation to nucleus" EXACT [GOC:mah] is_a: GO:0006403 ! RNA localization intersection_of: GO:0006403 ! RNA localization intersection_of: RO:0002339 GO:0005634 ! has target end location nucleus relationship: RO:0002339 GO:0005634 ! has target end location nucleus creation_date: 2016-07-19T17:00:49Z [Term] id: GO:0090741 name: pigment granule membrane namespace: cellular_component def: "Any membrane that is part of a pigment granule." [PMID:11294610] is_a: GO:0030659 ! cytoplasmic vesicle membrane is_a: GO:0098588 ! bounding membrane of organelle intersection_of: GO:0016020 ! membrane intersection_of: RO:0002007 GO:0048770 ! bounding layer of pigment granule relationship: RO:0002007 GO:0048770 ! bounding layer of pigment granule creation_date: 2017-05-16T22:33:39Z [Term] id: GO:0097014 name: ciliary plasm namespace: cellular_component def: "All of the contents of a cilium, excluding the plasma membrane surrounding the cilium." [GOC:BHF, GOC:cilia, GOC:dos, PMID:17895364] synonym: "cilium plasm" EXACT [] is_a: GO:0032838 ! plasma membrane bounded cell projection cytoplasm intersection_of: GO:0005737 ! cytoplasm intersection_of: BFO:0000050 GO:0005929 ! part of cilium relationship: BFO:0000050 GO:0005929 ! part of cilium creation_date: 2011-03-23T01:52:31Z [Term] id: GO:0097026 name: dendritic cell dendrite assembly namespace: biological_process def: "Formation of dendrites, branched cellular projections (or cytoplasmic extension) that are extended from the surface of a dendritic immune cell, and which enable the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells." [CL:0000451, GOC:BHF, PMID:12200351] is_a: GO:0120031 ! plasma membrane bounded cell projection assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0097511 ! results in assembly of dendritic cell dendrite relationship: RO:0002588 GO:0097511 ! results in assembly of dendritic cell dendrite creation_date: 2011-03-31T04:52:53Z [Term] id: GO:0097028 name: dendritic cell differentiation namespace: biological_process def: "The process in which a precursor cell type acquires the specialized features of a dendritic cell. A dendritic cell is a leukocyte of dendritic lineage specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation." [CL:0000451, GOC:pr] is_a: GO:1903131 ! mononuclear cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000451 ! results in acquisition of features of dendritic cell relationship: RO:0002315 CL:0000451 ! results in acquisition of features of dendritic cell creation_date: 2011-04-01T10:08:42Z [Term] id: GO:0097048 name: dendritic cell apoptotic process namespace: biological_process def: "Any apoptotic process in a dendritic cell, a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation." [CL:0000451, GOC:BHF, GOC:mtg_apoptosis, PMID:15059845] is_a: GO:0071887 ! leukocyte apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000451 ! occurs in dendritic cell relationship: BFO:0000066 CL:0000451 ! occurs in dendritic cell creation_date: 2011-05-04T02:18:59Z [Term] id: GO:0097049 name: motor neuron apoptotic process namespace: biological_process def: "Any apoptotic process in a motor neuron, an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement." [CL:0000100, GOC:BHF, GOC:mtg_apoptosis, PMID:14523086] synonym: "motoneuron apoptosis" EXACT [] is_a: GO:0051402 ! neuron apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000100 ! occurs in motor neuron relationship: BFO:0000066 CL:0000100 ! occurs in motor neuron creation_date: 2011-05-04T02:21:43Z [Term] id: GO:0097050 name: type B pancreatic cell apoptotic process namespace: biological_process def: "Any apoptotic process in a type B pancreatic cell, a cell located towards center of the islets of Langerhans that secretes insulin." [CL:0000169, GOC:BHF, GOC:mtg_apoptosis, PMID:16087305] synonym: "pancreatic B cell apoptosis" EXACT [] synonym: "pancreatic beta cell apoptosis" EXACT [] is_a: GO:1904019 ! epithelial cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000169 ! occurs in type B pancreatic cell relationship: BFO:0000066 CL:0000169 ! occurs in type B pancreatic cell creation_date: 2011-05-04T02:24:38Z [Term] id: GO:0097060 name: synaptic membrane namespace: cellular_component def: "A specialized area of membrane on either the presynaptic or the postsynaptic side of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell." [GOC:BHF, PMID:20410104] is_a: GO:0098590 ! plasma membrane region intersection_of: GO:0098590 ! plasma membrane region intersection_of: BFO:0000050 GO:0045202 ! part of synapse relationship: BFO:0000050 GO:0045202 ! part of synapse creation_date: 2011-06-07T11:22:09Z [Term] id: GO:0097084 name: vascular associated smooth muscle cell development namespace: biological_process def: "The process aimed at the progression of a vascular smooth muscle cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels." [GOC:BHF] synonym: "vascular smooth muscle cell development" EXACT [] is_a: GO:0055001 ! muscle cell development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 CL:0000359 ! results in development of vascular associated smooth muscle cell relationship: BFO:0000050 GO:0035886 ! part of vascular associated smooth muscle cell differentiation relationship: RO:0002296 CL:0000359 ! results in development of vascular associated smooth muscle cell creation_date: 2011-06-20T04:03:08Z [Term] id: GO:0097152 name: mesenchymal cell apoptotic process namespace: biological_process def: "Any apoptotic process in a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types." [CL:0000134, GOC:mtg_apoptosis, GOC:yaf, PMID:18231833] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0008019 ! occurs in mesenchymal cell relationship: BFO:0000066 CL:0008019 ! occurs in mesenchymal cell creation_date: 2011-09-06T02:31:59Z [Term] id: GO:0097164 name: ammonium ion metabolic process namespace: biological_process def: "The chemical reactions and pathways involving the ammonium ion." [GOC:dhl, GOC:tb, PMID:14671018] synonym: "ammonium ion metabolism" EXACT [] is_a: GO:0006807 ! nitrogen compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:28938 ! has primary input or output ammonium relationship: RO:0004007 CHEBI:28938 ! has primary input or output ammonium creation_date: 2011-09-28T04:21:30Z [Term] id: GO:0097190 name: apoptotic signaling pathway namespace: biological_process def: "The series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered." [GOC:mtg_apoptosis] synonym: "apoptotic signalling pathway" EXACT [GOC:mah] synonym: "induction of apoptosis by extracellular signals" EXACT [] is_a: GO:0007165 ! signal transduction relationship: BFO:0000050 GO:0006915 ! part of apoptotic process creation_date: 2011-11-23T09:30:23Z [Term] id: GO:0097194 name: execution phase of apoptosis namespace: biological_process def: "A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died." [GOC:mtg_apoptosis, PMID:21760595] synonym: "execution phase of apoptotic process" EXACT [] is_a: GO:0009987 ! cellular process relationship: BFO:0000050 GO:0006915 ! part of apoptotic process relationship: BFO:0000051 GO:0032060 ! has part bleb assembly creation_date: 2011-11-23T09:45:24Z [Term] id: GO:0097237 name: cellular response to toxic substance namespace: biological_process def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus." [GOC:pr] creation_date: 2012-02-02T12:23:31Z [Term] id: GO:0097254 name: renal tubular secretion namespace: biological_process def: "The elimination of substances from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine. Substances that are secreted include organic anions, ammonia, potassium and drugs." [GOC:rph, PMID:25287933, Wikipedia:Renal_secretion#Secretion] is_a: GO:0003014 ! renal system process is_a: GO:0007588 ! excretion creation_date: 2012-03-05T02:03:58Z [Term] id: GO:0097284 name: hepatocyte apoptotic process namespace: biological_process def: "Any apoptotic process in a hepatocyte, the main structural component of the liver." [CL:0000182, GOC:jc, GOC:mtg_apoptosis, PMID:15856020] is_a: GO:1904019 ! epithelial cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000182 ! occurs in hepatocyte relationship: BFO:0000066 CL:0000182 ! occurs in hepatocyte creation_date: 2012-03-29T10:23:21Z [Term] id: GO:0097355 name: protein localization to heterochromatin namespace: biological_process def: "Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into heterochromatin." [GOC:mah] synonym: "protein localisation to heterochromatin" EXACT [GOC:mah] is_a: GO:0071168 ! protein localization to chromatin intersection_of: GO:0008104 ! protein localization intersection_of: RO:0002339 GO:0000792 ! has target end location heterochromatin relationship: RO:0002339 GO:0000792 ! has target end location heterochromatin creation_date: 2012-07-03T03:19:07Z [Term] id: GO:0097360 name: chorionic trophoblast cell proliferation namespace: biological_process def: "The multiplication or reproduction of chorionic trophoblast cells, resulting in the expansion of their population." [CL:0011101, GOC:BHF, PMID:15150278] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0011101 ! acts on population of chorionic trophoblast cell relationship: RO:0012003 CL:0011101 ! acts on population of chorionic trophoblast cell creation_date: 2012-07-19T10:17:37Z [Term] id: GO:0097386 name: glial cell projection namespace: cellular_component def: "A prolongation or process extending from a glial cell." [GOC:mc] is_a: GO:0120025 ! plasma membrane bounded cell projection is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: GO:0120025 ! plasma membrane bounded cell projection intersection_of: BFO:0000050 CL:0000125 ! part of glial cell relationship: BFO:0000050 CL:0000125 ! part of glial cell creation_date: 2012-10-22T13:55:54Z [Term] id: GO:0097402 name: neuroblast migration namespace: biological_process def: "The orderly movement of a neuroblast from one site to another, often during the development of a multicellular organism or multicellular structure. A neuroblast is any cell that will divide and give rise to a neuron." [CL:0000031, GOC:jc, PMID:15543145] is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000031 ! results in movement of neuroblast (sensu Vertebrata) relationship: RO:0002565 CL:0000031 ! results in movement of neuroblast (sensu Vertebrata) creation_date: 2012-10-29T08:24:37Z [Term] id: GO:0097427 name: microtubule bundle namespace: cellular_component def: "An arrangement of closely apposed microtubules running parallel to each other." [NIF_Subcellular:sao1872343973] synonym: "microtubule fascicle" EXACT [] xref: NIF_Subcellular:sao1872343973 is_a: GO:0110165 ! cellular anatomical entity relationship: BFO:0000050 GO:0005856 ! part of cytoskeleton relationship: BFO:0000051 GO:0005874 ! has part microtubule creation_date: 2012-11-07T15:01:27Z [Term] id: GO:0097435 name: supramolecular fiber organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a supramolecular fiber, a polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure." [GOC:pr] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0099512 ! results in organization of supramolecular fiber relationship: RO:0002592 GO:0099512 ! results in organization of supramolecular fiber creation_date: 2012-11-27T15:46:25Z [Term] id: GO:0097473 name: retinal rod cell apoptotic process namespace: biological_process def: "Any apoptotic process in a retinal rod cell, one of the two photoreceptor cell types of the vertebrate retina." [CL:0000604, GOC:jc, PMID:17202487] synonym: "rod photoreceptor apoptotic process" EXACT [] is_a: GO:0051402 ! neuron apoptotic process is_a: GO:1990009 ! retinal cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000604 ! occurs in retinal rod cell relationship: BFO:0000066 CL:0000604 ! occurs in retinal rod cell creation_date: 2013-03-21T09:44:45Z [Term] id: GO:0097474 name: retinal cone cell apoptotic process namespace: biological_process def: "Any apoptotic process in a retinal cone cell, one of the two photoreceptor cell types of the vertebrate retina." [CL:0000573, GOC:jc] synonym: "cone photoreceptor apoptotic process" EXACT [] is_a: GO:0051402 ! neuron apoptotic process is_a: GO:1990009 ! retinal cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000573 ! occurs in retinal cone cell relationship: BFO:0000066 CL:0000573 ! occurs in retinal cone cell creation_date: 2013-03-21T09:46:22Z [Term] id: GO:0097475 name: motor neuron migration namespace: biological_process def: "The orderly movement of a motor neuron from one site to another. A motor neuron is an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement." [CL:0000100, GOC:yaf, PMID:20711475] is_a: GO:0001764 ! neuron migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000100 ! results in movement of motor neuron relationship: RO:0002565 CL:0000100 ! results in movement of motor neuron creation_date: 2013-04-23T13:00:46Z [Term] id: GO:0097476 name: spinal cord motor neuron migration namespace: biological_process def: "The orderly movement of a spinal cord motor neuron from one site to another. A spinal cord motor neuron is a motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement." [CL:0011001, GOC:yaf, PMID:20711475] is_a: GO:0097475 ! motor neuron migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0011001 ! results in movement of spinal cord motor neuron relationship: RO:0002565 CL:0011001 ! results in movement of spinal cord motor neuron creation_date: 2013-04-23T13:03:46Z [Term] id: GO:0097511 name: dendritic cell dendrite namespace: cellular_component def: "A branched cellular projection (or cytoplasmic extension) that is extended from the surface of a dendritic immune cell, and which enables the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells." [CL:0000451, GOC:BHF, GOC:cjm, PMID:12200351] is_a: GO:0120025 ! plasma membrane bounded cell projection intersection_of: GO:0120025 ! plasma membrane bounded cell projection intersection_of: BFO:0000050 CL:0000451 ! part of dendritic cell relationship: BFO:0000050 CL:0000451 ! part of dendritic cell creation_date: 2013-10-16T13:02:25Z [Term] id: GO:0097512 name: cardiac myofibril namespace: cellular_component def: "A cardiac myofibril is a myofibril specific to cardiac muscle cells." [GOC:cjm, GOC:devbiol] is_a: GO:0030016 ! myofibril intersection_of: GO:0030016 ! myofibril intersection_of: BFO:0000050 CL:0000746 ! part of cardiac muscle cell relationship: BFO:0000050 CL:0000746 ! part of cardiac muscle cell creation_date: 2013-10-16T13:04:58Z [Term] id: GO:0097524 name: sperm plasma membrane namespace: cellular_component def: "A plasma membrane that is part of a sperm cell." [GOC:cjm] is_a: GO:0005886 ! plasma membrane intersection_of: GO:0005886 ! plasma membrane intersection_of: BFO:0000050 CL:0000019 ! part of sperm relationship: BFO:0000050 CL:0000019 ! part of sperm creation_date: 2013-10-18T11:31:17Z [Term] id: GO:0097529 name: myeloid leukocyte migration namespace: biological_process def: "The movement of a myeloid leukocyte within or between different tissues and organs of the body." [GOC:cvs, PMID:22342843, PMID:24157461] is_a: GO:0050900 ! leukocyte migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000766 ! results in movement of myeloid leukocyte relationship: RO:0002565 CL:0000766 ! results in movement of myeloid leukocyte creation_date: 2013-11-11T13:59:43Z [Term] id: GO:0097534 name: lymphoid lineage cell migration namespace: biological_process def: "The orderly movement of a lymphoid lineage cell from one site to another. A lymphoid lineage cell, also called a lymphoid lineage restricted progenitor cell, is a progenitor cell restricted to the lymphoid lineage." [GOC:pr, PMID:22342843] synonym: "lymphoid lineage restricted progenitor cell migration" EXACT [] is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000838 ! results in movement of lymphoid lineage restricted progenitor cell relationship: RO:0002565 CL:0000838 ! results in movement of lymphoid lineage restricted progenitor cell creation_date: 2013-11-28T10:47:15Z [Term] id: GO:0097576 name: vacuole fusion namespace: biological_process def: "Merging of two or more vacuoles, or of vacuoles and vesicles within a cell to form a single larger vacuole." [GOC:pr, GOC:vw, Wikipedia:Vacuole] is_a: GO:0007033 ! vacuole organization is_a: GO:0048284 ! organelle fusion intersection_of: GO:0009987 ! cellular process intersection_of: RO:0012008 GO:0005773 ! results in fusion of vacuole relationship: RO:0012008 GO:0005773 ! results in fusion of vacuole creation_date: 2014-02-28T09:49:31Z [Term] id: GO:0097708 name: intracellular vesicle namespace: cellular_component def: "Any vesicle that is part of the intracellular region." [GOC:vesicles] is_a: GO:0031982 ! vesicle is_a: GO:0043231 ! intracellular membrane-bounded organelle intersection_of: GO:0031982 ! vesicle intersection_of: BFO:0000050 GO:0005622 ! part of intracellular anatomical structure creation_date: 2016-03-29T17:39:45Z [Term] id: GO:0097711 name: ciliary basal body-plasma membrane docking namespace: biological_process def: "The docking of a cytosolic centriole/basal body to the plasma membrane via the ciliary transition fibers. In some species this may happen via an intermediate step, by first docking to the ciliary vesicle via the ciliary transition fibers. The basal body-ciliary vesicle then relocates to the plasma membrane, followed by the ciliary vesicle fusing with the plasma membrane, effectively attaching the basal body to the plasma membrane." [GOC:cilia, PMID:13978319, PMID:23348840, PMID:23530209, PMID:25686250, PMID:26981235, Reactome:R-HSA-5620912.1] synonym: "ciliary basal body docking" EXACT [] xref: Reactome:R-HSA-5620912.1 is_a: GO:0140056 ! organelle localization by membrane tethering relationship: BFO:0000050 GO:0060271 ! part of cilium assembly creation_date: 2016-08-05T16:12:33Z [Term] id: GO:0097712 name: vesicle targeting, trans-Golgi to periciliary membrane compartment namespace: biological_process def: "The process in which vesicles formed at the trans-Golgi network are directed to the plasma membrane surrounding the base of the cilium, including the ciliary pocket, mediated by molecules at the vesicle membrane and target membrane surfaces." [GOC:cilia, PMID:20106869, PMID:23351793, PMID:24814148, PMID:26485645, Reactome:R-HSA-5620920.1] is_a: GO:0048199 ! vesicle targeting, to, from or within Golgi relationship: BFO:0000050 GO:0060271 ! part of cilium assembly creation_date: 2016-08-05T16:16:28Z [Term] id: GO:0097722 name: sperm motility namespace: biological_process def: "Any process involved in the controlled movement of a sperm cell." [GOC:cilia, GOC:krc] synonym: "sperm movement" EXACT [] is_a: GO:0022414 ! reproductive process is_a: GO:0048870 ! cell motility intersection_of: GO:0048870 ! cell motility intersection_of: RO:0002565 CL:0000019 ! results in movement of sperm relationship: RO:0002565 CL:0000019 ! results in movement of sperm creation_date: 2016-09-01T12:00:45Z [Term] id: GO:0097734 name: extracellular exosome biogenesis namespace: biological_process def: "The assembly and secretion of an extracellular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane." [GOC:bf, GOC:PARL, PMID:19442504, PMID:25392495] synonym: "exosome assembly or secretion" EXACT [] synonym: "exosome biogenesis" EXACT [] synonym: "exosome production" EXACT [] is_a: GO:0140112 ! extracellular vesicle biogenesis creation_date: 2016-10-03T14:35:25Z [Term] id: GO:0098523 name: neuromuscular junction of myotube namespace: cellular_component def: "A neuromuscular junction in which the target muscle cell is a myotube." [GOC:dos] is_a: GO:0031594 ! neuromuscular junction intersection_of: GO:0045202 ! synapse intersection_of: RO:0002131 CL:0000100 ! overlaps motor neuron intersection_of: RO:0002131 CL:0002372 ! overlaps myotube relationship: RO:0002131 CL:0002372 ! overlaps myotube creation_date: 2013-10-14T12:05:12Z [Term] id: GO:0098528 name: skeletal muscle fiber differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle fiber cell. Skeletal muscle fiber differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual skeletal muscle fibers fuse to form bigger myotubes and start to contract." [GOC:dos] is_a: GO:0014902 ! myotube differentiation is_a: GO:0035914 ! skeletal muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0008002 ! results in acquisition of features of skeletal muscle fiber relationship: RO:0002315 CL:0008002 ! results in acquisition of features of skeletal muscle fiber creation_date: 2013-10-15T14:00:34Z [Term] id: GO:0098542 name: defense response to other organism namespace: biological_process def: "Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism." [GOC:dos] is_a: GO:0006952 ! defense response is_a: GO:0051707 ! response to other organism intersection_of: GO:0006952 ! defense response intersection_of: RO:0004009 NCBITaxon_Union:0000030 ! has primary input creation_date: 2013-11-11T12:59:11Z [Term] id: GO:0098588 name: bounding membrane of organelle namespace: cellular_component def: "The lipid bilayer that forms the outer-most layer of an organelle." [GOC:dos] is_a: GO:0031090 ! organelle membrane intersection_of: GO:0016020 ! membrane intersection_of: RO:0002007 GO:0043226 ! bounding layer of organelle relationship: RO:0002007 GO:0043226 ! bounding layer of organelle creation_date: 2014-02-26T13:41:31Z [Term] id: GO:0098590 name: plasma membrane region namespace: cellular_component def: "A membrane that is a (regional) part of the plasma membrane." [GOC:dos] synonym: "region of plasma membrane" EXACT [] is_a: GO:0016020 ! membrane intersection_of: GO:0016020 ! membrane intersection_of: BFO:0000050 GO:0005886 ! part of plasma membrane relationship: BFO:0000050 GO:0005886 ! part of plasma membrane creation_date: 2014-03-06T11:55:32Z [Term] id: GO:0098609 name: cell-cell adhesion namespace: biological_process def: "The attachment of one cell to another cell via adhesion molecules." [GOC:dos] is_a: GO:0007155 ! cell adhesion creation_date: 2014-04-16T13:40:03Z [Term] id: GO:0098635 name: protein complex involved in cell-cell adhesion namespace: cellular_component def: "Any protein complex that is capable of carrying out some part of the process of cell-cell adhesion." [GOC:dos] is_a: GO:0098636 ! protein complex involved in cell adhesion intersection_of: GO:0032991 ! protein-containing complex intersection_of: RO:0002216 GO:0098609 ! capable of part of cell-cell adhesion relationship: RO:0002216 GO:0098609 ! capable of part of cell-cell adhesion [Term] id: GO:0098636 name: protein complex involved in cell adhesion namespace: cellular_component def: "Any protein complex that is capable of carrying out some part of the process of cell adhesion to the cell matrix or to another cell." [GOC:dos] is_a: GO:0032991 ! protein-containing complex intersection_of: GO:0032991 ! protein-containing complex intersection_of: RO:0002216 GO:0007155 ! capable of part of cell adhesion relationship: RO:0002216 GO:0007155 ! capable of part of cell adhesion [Term] id: GO:0098642 name: network-forming collagen trimer namespace: cellular_component def: "A collagen trimer that forms networks." [PMID:21421911] is_a: GO:0005581 ! collagen trimer intersection_of: GO:0005581 ! collagen trimer intersection_of: BFO:0000050 GO:0098645 ! part of collagen network relationship: BFO:0000050 GO:0098645 ! part of collagen network [Term] id: GO:0098643 name: banded collagen fibril namespace: cellular_component def: "A supramolecular assembly of fibrillar collagen complexes in the form of a long fiber (fibril) with transverse striations (bands)." [GOC:dos, PMID:21421911] is_a: GO:0098644 ! complex of collagen trimers is_a: GO:0099512 ! supramolecular fiber [Term] id: GO:0098644 name: complex of collagen trimers namespace: cellular_component def: "A complex of collagen trimers such as a fibril or collagen network." [GOC:dos] synonym: "Supramolecular aggregate of collagen" EXACT [PMID:19693541] synonym: "Supramolecular collagen assembly" EXACT [PMID:21421911] is_a: GO:0099080 ! supramolecular complex is_a: PR:000050567 ! protein-containing material entity relationship: BFO:0000050 GO:0062023 ! part of collagen-containing extracellular matrix relationship: BFO:0000051 GO:0005581 ! has part collagen trimer [Term] id: GO:0098645 name: collagen network namespace: cellular_component def: "A supramolecular complex that consists of collagen triple helices associated to form a network." [GOC:dos, PMID:21421911] is_a: GO:0098644 ! complex of collagen trimers is_a: GO:0099081 ! supramolecular polymer [Term] id: GO:0098651 name: basement membrane collagen trimer namespace: cellular_component def: "Any collagen timer that is part of a basement membrane." [GOC:dos, PMID:21421911] is_a: GO:0005581 ! collagen trimer intersection_of: GO:0005581 ! collagen trimer intersection_of: BFO:0000050 GO:0005604 ! part of basement membrane relationship: BFO:0000050 GO:0005604 ! part of basement membrane [Term] id: GO:0098655 name: monoatomic cation transmembrane transport namespace: biological_process def: "The process in which a monoatomic cation is transported across a membrane. Monatomic cations (also called simple cations) are positively charged ions consisting of exactly one atom." [GOC:dos, GOC:vw] is_a: GO:0006812 ! monoatomic cation transport is_a: GO:0034220 ! monoatomic ion transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002342 GO:0016020 ! results in transport across membrane intersection_of: RO:0004009 CHEBI:23906 ! has primary input monoatomic cation [Term] id: GO:0098657 name: import into cell namespace: biological_process def: "The directed movement of some substance from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis." [GOC:dos] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002338 GO:0005576 ! has target start location extracellular region intersection_of: RO:0002339 GO:0005737 ! has target end location cytoplasm intersection_of: RO:0004009 CHEBI:24431 ! has primary input chemical entity relationship: RO:0002338 GO:0005576 ! has target start location extracellular region relationship: RO:0002339 GO:0005737 ! has target end location cytoplasm relationship: RO:0004009 CHEBI:24431 ! has primary input chemical entity [Term] id: GO:0098660 name: inorganic ion transmembrane transport namespace: biological_process def: "The process in which an inorganic ion is transported across a membrane." [GOC:mah] synonym: "inorganic ion membrane transport" EXACT [] synonym: "transmembrane inorganic ion transport" EXACT [GOC:dph, GOC:tb] is_a: GO:0055085 ! transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002342 GO:0016020 ! results in transport across membrane intersection_of: RO:0004009 CHEBI:36914 ! has primary input inorganic ion relationship: RO:0004009 CHEBI:36914 ! has primary input inorganic ion [Term] id: GO:0098661 name: inorganic anion transmembrane transport namespace: biological_process def: "The process in which an inorganic anion is transported across a membrane." [GOC:mah] synonym: "inorganic anion membrane transport" EXACT [] synonym: "transmembrane inorganic anion transport" EXACT [GOC:dph, GOC:tb] is_a: GO:0015698 ! inorganic anion transport is_a: GO:0098660 ! inorganic ion transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002342 GO:0016020 ! results in transport across membrane intersection_of: RO:0004009 CHEBI:24834 ! has primary input inorganic anion [Term] id: GO:0098662 name: inorganic cation transmembrane transport namespace: biological_process def: "A process in which an inorganic cation is transported from one side of a membrane to the other by means of some agent such as a transporter or pore." [GOC:mah] synonym: "inorganic cation membrane transport" EXACT [] synonym: "transmembrane inorganic cation transport" EXACT [GOC:dph, GOC:tb] is_a: GO:0098660 ! inorganic ion transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002342 GO:0016020 ! results in transport across membrane intersection_of: RO:0004009 CHEBI:36915 ! has primary input inorganic cation relationship: RO:0004009 CHEBI:36915 ! has primary input inorganic cation [Term] id: GO:0098722 name: asymmetric stem cell division namespace: biological_process def: "Division of a stem cell during which it retains its identity and buds off a daughter cell with a new identity." [GOC:dos, PMID:18513950] is_a: GO:0008356 ! asymmetric cell division is_a: GO:0017145 ! stem cell division intersection_of: GO:0008356 ! asymmetric cell division intersection_of: RO:0004009 CL:0000034 ! has primary input stem cell [Term] id: GO:0098723 name: skeletal muscle myofibril namespace: cellular_component def: "A myofibril of a skeletal muscle fiber." [GOC:dos] is_a: GO:0030016 ! myofibril intersection_of: GO:0030016 ! myofibril intersection_of: BFO:0000050 CL:0008002 ! part of skeletal muscle fiber relationship: BFO:0000050 CL:0008002 ! part of skeletal muscle fiber [Term] id: GO:0098727 name: maintenance of cell number namespace: biological_process def: "Any process by which the numbers of cells of a particular type or in a tissue are maintained." [GOC:dos] is_a: GO:0032502 ! developmental process [Term] id: GO:0098728 name: germline stem cell asymmetric division namespace: biological_process def: "The self-renewing division of a germline stem cell, to produce a daughter stem cell and a daughter germ cell which will divide to form one or more gametes." [GOC:dos] is_a: GO:0042078 ! germ-line stem cell division is_a: GO:0098722 ! asymmetric stem cell division intersection_of: GO:0008356 ! asymmetric cell division intersection_of: RO:0004009 CL:0000014 ! has primary input germ line stem cell [Term] id: GO:0098751 name: bone cell development namespace: biological_process def: "The process whose specific outcome is the progression of a bone cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:dos] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0001035 ! results in development of bone cell relationship: BFO:0000050 GO:0060348 ! part of bone development relationship: RO:0002296 CL:0001035 ! results in development of bone cell [Term] id: GO:0098754 name: detoxification namespace: biological_process def: "Any process that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance." [GOC:dos] is_a: GO:0008150 ! biological_process relationship: BFO:0000050 GO:0009636 ! part of response to toxic substance [Term] id: GO:0098773 name: skin epidermis development namespace: biological_process def: "The process whose specific outcome is the progression of the skin epidermis over time, from its formation to the mature structure." [GOC:dos] is_a: GO:0008544 ! epidermis development is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001003 ! results in development of skin epidermis relationship: BFO:0000050 GO:0043588 ! part of skin development relationship: RO:0002296 UBERON:0001003 ! results in development of skin epidermis [Term] id: GO:0098793 name: presynapse namespace: cellular_component def: "The part of a synapse that is part of the presynaptic cell." [GOC:dos] synonym: "presynaptic terminal" EXACT [] is_a: GO:0110165 ! cellular anatomical entity relationship: BFO:0000050 CL:0000540 ! part of neuron relationship: BFO:0000050 GO:0045202 ! part of synapse [Term] id: GO:0098794 name: postsynapse namespace: cellular_component def: "The part of a synapse that is part of the post-synaptic cell." [GOC:dos] is_a: GO:0110165 ! cellular anatomical entity relationship: BFO:0000050 CL:0000000 ! part of cell relationship: BFO:0000050 GO:0045202 ! part of synapse [Term] id: GO:0098796 name: membrane protein complex namespace: cellular_component def: "Any protein complex that is part of a membrane." [GOC:dos] is_a: GO:0032991 ! protein-containing complex intersection_of: GO:0032991 ! protein-containing complex intersection_of: BFO:0000050 GO:0016020 ! part of membrane relationship: BFO:0000050 GO:0016020 ! part of membrane [Term] id: GO:0098797 name: plasma membrane protein complex namespace: cellular_component def: "Any protein complex that is part of the plasma membrane." [GOC:dos] is_a: GO:0098796 ! membrane protein complex intersection_of: GO:0032991 ! protein-containing complex intersection_of: BFO:0000050 GO:0005886 ! part of plasma membrane relationship: BFO:0000050 GO:0005886 ! part of plasma membrane [Term] id: GO:0098801 name: regulation of renal system process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by the renal system." [GOC:dos] is_a: GO:0044057 ! regulation of system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003014 ! regulates (processual) renal system process relationship: RO:0002211 GO:0003014 ! regulates (processual) renal system process [Term] id: GO:0098813 name: nuclear chromosome segregation namespace: biological_process def: "The process in which genetic material, in the form of nuclear chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. Nuclear chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles." [GOC:dos] is_a: GO:0007059 ! chromosome segregation [Term] id: GO:0098840 name: protein transport along microtubule namespace: biological_process def: "The directed movement of a protein along a microtubule, mediated by motor proteins." [PMID:25987607] is_a: GO:0006886 ! intracellular protein transport is_a: GO:0010970 ! transport along microtubule is_a: GO:0099118 ! microtubule-based protein transport intersection_of: GO:0046907 ! intracellular transport intersection_of: RO:0002341 GO:0005874 ! results in transport along microtubule intersection_of: RO:0004009 PR:000000001 ! has primary input protein [Term] id: GO:0098858 name: actin-based cell projection namespace: cellular_component def: "A cell projection supported by an assembly of actin filaments, and which lacks microtubules." [PMID:15661519] is_a: GO:0120025 ! plasma membrane bounded cell projection relationship: BFO:0000051 GO:0005884 ! has part actin filament [Term] id: GO:0098867 name: intramembranous bone growth namespace: biological_process def: "The increase in size or mass of an intramembranous bone that contributes to the shaping of the bone." [PMID:26399686] is_a: GO:0098868 ! bone growth intersection_of: GO:0048589 ! developmental growth intersection_of: RO:0002343 UBERON:0002514 ! results in growth of intramembranous bone relationship: RO:0002343 UBERON:0002514 ! results in growth of intramembranous bone [Term] id: GO:0098868 name: bone growth namespace: biological_process def: "The increase in size or mass of a bone that contributes to the shaping of that bone." [GOC:dos] is_a: GO:0035265 ! organ growth intersection_of: GO:0048589 ! developmental growth intersection_of: RO:0002343 UBERON:0001474 ! results in growth of bone element relationship: BFO:0000050 GO:0060348 ! part of bone development relationship: RO:0002343 UBERON:0001474 ! results in growth of bone element [Term] id: GO:0098871 name: postsynaptic actin cytoskeleton namespace: cellular_component def: "The actin cytoskeleton that is part of a postsynapse." [GOC:dos] is_a: GO:0015629 ! actin cytoskeleton is_a: GO:0099571 ! postsynaptic cytoskeleton intersection_of: GO:0015629 ! actin cytoskeleton intersection_of: BFO:0000050 GO:0098794 ! part of postsynapse [Term] id: GO:0098876 name: vesicle-mediated transport to the plasma membrane namespace: biological_process def: "The directed movement of substances to the plasma membrane in transport vesicles that fuse with the plasma membrane by exocytosis." [GOC:dos] is_a: GO:0016192 ! vesicle-mediated transport is_a: GO:0051668 ! localization within membrane intersection_of: GO:0006810 ! transport intersection_of: RO:0002339 GO:0005886 ! has target end location plasma membrane intersection_of: RO:0002608 GO:0031982 ! process has causal agent vesicle relationship: RO:0002230 GO:0006887 ! ends with exocytosis relationship: RO:0002339 GO:0005886 ! has target end location plasma membrane [Term] id: GO:0098883 name: synapse pruning namespace: biological_process def: "A cellular process that results in the controlled breakdown of synapse. After it starts the process is continuous until the synapse has disappeared." [GOC:dos, PMID:12062020, PMID:18083105, PMID:22632716, PMID:29844190] synonym: "synapse clearance" EXACT [GOC:aruk, GOC:bc, PMID:22632716] synonym: "synapse elimination" EXACT [GOC:aruk, GOC:bc, PMID:18083105, PMID:29844190] synonym: "synapse removal" EXACT [GOC:aruk, GOC:bc, PMID:22632716] is_a: GO:0050808 ! synapse organization is_a: GO:0150146 ! cell junction disassembly intersection_of: GO:0022411 ! cellular component disassembly intersection_of: RO:0002590 GO:0045202 ! results in disassembly of synapse relationship: RO:0002590 GO:0045202 ! results in disassembly of synapse [Term] id: GO:0098900 name: regulation of action potential namespace: biological_process def: "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:dos, GOC:dph, GOC:go_curators, GOC:tb, ISBN:978-0-07-139011-8] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0050789 ! regulation of biological process intersection_of: RO:0002211 GO:0001508 ! regulates (processual) action potential relationship: RO:0002211 GO:0001508 ! regulates (processual) action potential [Term] id: GO:0098901 name: regulation of cardiac muscle cell action potential namespace: biological_process def: "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:dos, GOC:mtg_cardiac_conduct_nov11] is_a: GO:0098900 ! regulation of action potential intersection_of: GO:0050789 ! regulation of biological process intersection_of: RO:0002211 GO:0086001 ! regulates (processual) cardiac muscle cell action potential relationship: RO:0002211 GO:0086001 ! regulates (processual) cardiac muscle cell action potential [Term] id: GO:0098904 name: regulation of AV node cell action potential namespace: biological_process def: "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an atrioventricular node myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "regulation of atrioventricular node cardiac muscle cell action potential" EXACT [] synonym: "regulation of AV node cardiac muscle cell action potential" EXACT [] is_a: GO:0010646 ! regulation of cell communication is_a: GO:0098901 ! regulation of cardiac muscle cell action potential intersection_of: GO:0050789 ! regulation of biological process intersection_of: RO:0002211 GO:0086016 ! regulates (processual) AV node cell action potential relationship: RO:0002211 GO:0086016 ! regulates (processual) AV node cell action potential creation_date: 2011-11-10T08:58:56Z [Term] id: GO:0098906 name: regulation of Purkinje myocyte action potential namespace: biological_process def: "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a Purkinje myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] is_a: GO:0010646 ! regulation of cell communication is_a: GO:0098901 ! regulation of cardiac muscle cell action potential intersection_of: GO:0050789 ! regulation of biological process intersection_of: RO:0002211 GO:0086017 ! regulates (processual) Purkinje myocyte action potential relationship: RO:0002211 GO:0086017 ! regulates (processual) Purkinje myocyte action potential creation_date: 2011-11-10T08:58:56Z [Term] id: GO:0098907 name: regulation of SA node cell action potential namespace: biological_process def: "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an SA node cardiac myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "regulation of SA node cardiac muscle cell action potential" EXACT [] synonym: "regulation of SAN cardiac muscle cell action potential" EXACT [] synonym: "regulation of sinoatrial node cardiac muscle cell action potential" EXACT [] is_a: GO:0010646 ! regulation of cell communication is_a: GO:0098901 ! regulation of cardiac muscle cell action potential intersection_of: GO:0050789 ! regulation of biological process intersection_of: RO:0002211 GO:0086015 ! regulates (processual) SA node cell action potential relationship: RO:0002211 GO:0086015 ! regulates (processual) SA node cell action potential creation_date: 2011-11-10T08:50:15Z [Term] id: GO:0098908 name: regulation of neuronal action potential namespace: biological_process def: "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a neuron. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:dph, GOC:isa_complete, GOC:tb] is_a: GO:0051969 ! regulation of transmission of nerve impulse is_a: GO:0098900 ! regulation of action potential intersection_of: GO:0050789 ! regulation of biological process intersection_of: RO:0002211 GO:0019228 ! regulates (processual) neuronal action potential relationship: RO:0002211 GO:0019228 ! regulates (processual) neuronal action potential [Term] id: GO:0098916 name: anterograde trans-synaptic signaling namespace: biological_process def: "Cell-cell signaling from pre to post-synapse, across the synaptic cleft." [GOC:dos] is_a: GO:0099537 ! trans-synaptic signaling intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: RO:0002231 GO:0098793 ! has start location presynapse intersection_of: RO:0002232 GO:0098794 ! has end location postsynapse relationship: RO:0002231 GO:0098793 ! has start location presynapse relationship: RO:0002232 GO:0098794 ! has end location postsynapse [Term] id: GO:0098917 name: retrograde trans-synaptic signaling namespace: biological_process def: "Cell-cell signaling from post to pre-synapse, across the synaptic cleft." [GOC:dos] is_a: GO:0099537 ! trans-synaptic signaling intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: RO:0002231 GO:0098794 ! has start location postsynapse intersection_of: RO:0002232 GO:0098793 ! has end location presynapse relationship: RO:0002231 GO:0098794 ! has start location postsynapse relationship: RO:0002232 GO:0098793 ! has end location presynapse [Term] id: GO:0098920 name: retrograde trans-synaptic signaling by lipid namespace: biological_process def: "Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a lipid ligand." [GOC:dos] is_a: GO:0098917 ! retrograde trans-synaptic signaling is_a: GO:0099541 ! trans-synaptic signaling by lipid intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: RO:0002231 GO:0098794 ! has start location postsynapse intersection_of: RO:0002232 GO:0098793 ! has end location presynapse intersection_of: RO:0002608 CHEBI:18059 ! process has causal agent lipid [Term] id: GO:0098926 name: postsynaptic signal transduction namespace: biological_process def: "Signal transduction in which the initial step occurs in a postsynapse." [GOC:dos] is_a: GO:0007165 ! signal transduction intersection_of: GO:0007165 ! signal transduction intersection_of: RO:0002231 GO:0098794 ! has start location postsynapse relationship: BFO:0000050 GO:0099536 ! part of synaptic signaling relationship: RO:0002231 GO:0098794 ! has start location postsynapse [Term] id: GO:0098928 name: presynaptic signal transduction namespace: biological_process def: "Signal transduction in which the initial step occurs in a presynapse." [GOC:dos] is_a: GO:0007165 ! signal transduction intersection_of: GO:0007165 ! signal transduction intersection_of: RO:0002231 GO:0098793 ! has start location presynapse relationship: RO:0002231 GO:0098793 ! has start location presynapse [Term] id: GO:0098974 name: postsynaptic actin cytoskeleton organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the postsynaptic actin cytoskeleton." [GOC:dos] is_a: GO:0030036 ! actin cytoskeleton organization is_a: GO:0099188 ! postsynaptic cytoskeleton organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0098871 ! results in organization of postsynaptic actin cytoskeleton relationship: RO:0002592 GO:0098871 ! results in organization of postsynaptic actin cytoskeleton [Term] id: GO:0098975 name: postsynapse of neuromuscular junction namespace: cellular_component def: "The postsynapse of a neuromuscular junction. In vertebrate muscles this includes the motor end-plate, consisting of postjunctional folds of the sarcolemma." [GOC:dos, Wikipedia:Neuromuscular_junction&oldid=723623502] is_a: GO:0098794 ! postsynapse is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: GO:0098794 ! postsynapse intersection_of: BFO:0000050 CL:0000187 ! part of muscle cell intersection_of: BFO:0000050 GO:0031594 ! part of neuromuscular junction relationship: BFO:0000050 CL:0000187 ! part of muscle cell relationship: BFO:0000050 GO:0031594 ! part of neuromuscular junction [Term] id: GO:0098981 name: cholinergic synapse namespace: cellular_component def: "A synapse that uses acetylcholine as a neurotransmitter." [GOC:dos] is_a: GO:0045202 ! synapse intersection_of: GO:0045202 ! synapse intersection_of: RO:0002215 GO:0007271 ! capable of synaptic transmission, cholinergic relationship: RO:0002215 GO:0007271 ! capable of synaptic transmission, cholinergic [Term] id: GO:0098992 name: neuronal dense core vesicle namespace: cellular_component def: "A dense core vesicle (granule) that is part of a neuron. These vesicles typically contain neuropeptides. They can be found in all parts of neurons, including the soma, dendrites, axonal swellings (varicosities) and synaptic terminals." [GOC:dos, ISBN:978-0-07-181001-2, Wikipedia:Neuropeptide&oldid=713905176] is_a: GO:0031045 ! dense core granule intersection_of: GO:0031045 ! dense core granule intersection_of: BFO:0000050 CL:0000540 ! part of neuron relationship: BFO:0000050 CL:0000540 ! part of neuron [Term] id: GO:0099003 name: vesicle-mediated transport in synapse namespace: biological_process def: "Any vesicle-mediated transport that occurs in a synapse." [GOC:dos] is_a: GO:0016192 ! vesicle-mediated transport intersection_of: GO:0016192 ! vesicle-mediated transport intersection_of: BFO:0000066 GO:0045202 ! occurs in synapse relationship: BFO:0000066 GO:0045202 ! occurs in synapse relationship: RO:0002160 NCBITaxon:33208 ! only in taxon Metazoa relationship: RO:0002162 NCBITaxon:33208 {all_only="true"} ! in taxon Metazoa [Term] id: GO:0099012 name: neuronal dense core vesicle membrane namespace: cellular_component def: "The lipid bilayer surrounding a neuronal dense core vesicle." [GOC:dos] is_a: GO:0032127 ! dense core granule membrane intersection_of: GO:0016020 ! membrane intersection_of: RO:0002007 GO:0098992 ! bounding layer of neuronal dense core vesicle relationship: RO:0002007 GO:0098992 ! bounding layer of neuronal dense core vesicle [Term] id: GO:0099014 name: neuronal dense core vesicle organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuronal dense core vesicle." [GOC:dos] is_a: GO:0061109 ! dense core granule organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0098992 ! results in organization of neuronal dense core vesicle relationship: RO:0002592 GO:0098992 ! results in organization of neuronal dense core vesicle [Term] id: GO:0099054 name: presynapse assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form a presynapse." [GOC:bf, GOC:dos, GOC:PARL, PMID:24449494] synonym: "presynapse biogenesis" EXACT [GOC:mah] synonym: "presynaptic terminal assembly" EXACT [PMID:24449494] is_a: GO:0022607 ! cellular component assembly is_a: GO:0099172 ! presynapse organization intersection_of: GO:0009987 ! cellular process intersection_of: RO:0002588 GO:0098793 ! results in assembly of presynapse relationship: BFO:0000050 GO:0007416 ! part of synapse assembly relationship: RO:0002588 GO:0098793 ! results in assembly of presynapse [Term] id: GO:0099068 name: postsynapse assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form a postsynapse." [GOC:bf, GOC:dos, GOCL:PARL] synonym: "postsynapse biogenesis" EXACT [GOC:mah] is_a: GO:0022607 ! cellular component assembly is_a: GO:0099173 ! postsynapse organization intersection_of: GO:0009987 ! cellular process intersection_of: RO:0002588 GO:0098794 ! results in assembly of postsynapse relationship: BFO:0000050 GO:0007416 ! part of synapse assembly relationship: RO:0002588 GO:0098794 ! results in assembly of postsynapse [Term] id: GO:0099080 name: supramolecular complex namespace: cellular_component def: "A cellular component that consists of an indeterminate number of proteins or macromolecular complexes, organized into a regular, higher-order structure such as a polymer, sheet, network or a fiber." [GOC:dos] is_a: GO:0110165 ! cellular anatomical entity [Term] id: GO:0099081 name: supramolecular polymer namespace: cellular_component def: "A polymeric supramolecular structure." [GOC:dos] is_a: GO:0099080 ! supramolecular complex intersection_of: GO:0099080 ! supramolecular complex intersection_of: RO:0000053 PATO:0015006 ! has characteristic polymeric relationship: RO:0000053 PATO:0015006 ! has characteristic polymeric [Term] id: GO:0099082 name: retrograde trans-synaptic signaling by neuropeptide namespace: biological_process def: "Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a neuropeptide." [GOC:bf, GOC:dos, GOC:PARL, PMID:19448629] is_a: GO:0098917 ! retrograde trans-synaptic signaling is_a: GO:0099540 ! trans-synaptic signaling by neuropeptide intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: RO:0002231 GO:0098794 ! has start location postsynapse intersection_of: RO:0002232 GO:0098793 ! has end location presynapse intersection_of: RO:0002608 CHEBI:16670 ! process has causal agent peptide [Term] id: GO:0099083 name: retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission namespace: biological_process def: "Modulation of synaptic transmittion by cell-cell signaling across the synaptic cleft from postsynapse to presynapse, mediated by a neuropeptide." [GOC:bf, GOC:dos, GOC:PARL, PMID:19448629] is_a: GO:0099082 ! retrograde trans-synaptic signaling by neuropeptide is_a: GO:0099551 ! trans-synaptic signaling by neuropeptide, modulating synaptic transmission intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: RO:0002211 GO:0007268 ! regulates (processual) chemical synaptic transmission intersection_of: RO:0002231 GO:0098794 ! has start location postsynapse intersection_of: RO:0002232 GO:0098793 ! has end location presynapse intersection_of: RO:0002608 CHEBI:16670 ! process has causal agent peptide [Term] id: GO:0099098 name: microtubule polymerization based movement namespace: biological_process def: "The movement of a cellular component as a result of microtubule polymerization." [GOC:cjm, ISBN:0815316194] is_a: GO:0007018 ! microtubule-based movement intersection_of: GO:0007018 ! microtubule-based movement intersection_of: BFO:0000051 GO:0046785 ! has part microtubule polymerization relationship: BFO:0000051 GO:0046785 ! has part microtubule polymerization [Term] id: GO:0099111 name: microtubule-based transport namespace: biological_process def: "A microtubule-based process that results in the transport of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules." [GOC:cjm, ISBN:0815316194] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002608 GO:0005874 ! process has causal agent microtubule relationship: RO:0002608 GO:0005874 ! process has causal agent microtubule [Term] id: GO:0099112 name: microtubule polymerization based protein transport namespace: biological_process def: "The transport of a protein driven by polymerization of a microtubule to which it is attached." [GOC:dos, GOC:vw, PMID:11018050] is_a: GO:0007017 ! microtubule-based process is_a: GO:0045184 ! establishment of protein localization is_a: GO:0046907 ! intracellular transport is_a: GO:0071702 ! organic substance transport is_a: GO:0099111 ! microtubule-based transport intersection_of: GO:0046907 ! intracellular transport intersection_of: BFO:0000051 GO:0046785 ! has part microtubule polymerization intersection_of: RO:0002608 GO:0005874 ! process has causal agent microtubule intersection_of: RO:0004009 CHEBI:36080 ! has primary input protein relationship: BFO:0000051 GO:0046785 ! has part microtubule polymerization [Term] id: GO:0099118 name: microtubule-based protein transport namespace: biological_process def: "A microtubule-based process that results in the transport of proteins." [GOC:vw] is_a: GO:0007017 ! microtubule-based process is_a: GO:0015031 ! protein transport is_a: GO:0099111 ! microtubule-based transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002608 GO:0005874 ! process has causal agent microtubule intersection_of: RO:0004009 PR:000000001 ! has primary input protein [Term] id: GO:0099140 name: presynaptic actin cytoskeleton organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the presynaptic actin cytoskeleton." [GOC:dos] is_a: GO:0030036 ! actin cytoskeleton organization is_a: GO:0099187 ! presynaptic cytoskeleton organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0099143 ! results in organization of presynaptic actin cytoskeleton relationship: RO:0002592 GO:0099143 ! results in organization of presynaptic actin cytoskeleton creation_date: 2017-06-09T18:34:19Z [Term] id: GO:0099143 name: presynaptic actin cytoskeleton namespace: cellular_component def: "The actin cytoskeleton that is part of a presynapse." [GOC:dos] is_a: GO:0015629 ! actin cytoskeleton is_a: GO:0099569 ! presynaptic cytoskeleton intersection_of: GO:0015629 ! actin cytoskeleton intersection_of: BFO:0000050 GO:0098793 ! part of presynapse creation_date: 2017-06-09T18:36:19Z [Term] id: GO:0099156 name: cell-cell signaling via exosome namespace: biological_process def: "Cell-cell signaling in which the ligand is carried between cells by an exosome." [GOC:dos, PMID:19837038] synonym: "exosome mediated" EXACT [] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: RO:0002608 GO:0070062 ! process has causal agent extracellular exosome relationship: RO:0002608 GO:0070062 ! process has causal agent extracellular exosome creation_date: 2017-07-05T16:40:45Z [Term] id: GO:0099157 name: trans-synaptic signaling via exosome namespace: biological_process def: "Transynaptic signaling in which the ligand is carried across the synapse by an exosome." [GOC:dos, PMID:19837038] synonym: "exosome mediated transynaptic signalling" EXACT [] synonym: "trans-synaptic signalling via exosome" EXACT [] is_a: GO:0099156 ! cell-cell signaling via exosome is_a: GO:0099537 ! trans-synaptic signaling intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: RO:0002608 GO:0070062 ! process has causal agent extracellular exosome creation_date: 2017-07-05T16:49:44Z [Term] id: GO:0099170 name: postsynaptic modulation of chemical synaptic transmission namespace: biological_process def: "Any process, acting in the postsynapse that results in modulation of chemical synaptic transmission." [GOC:dos] is_a: GO:0050804 ! modulation of chemical synaptic transmission intersection_of: GO:0050804 ! modulation of chemical synaptic transmission intersection_of: BFO:0000066 GO:0098794 ! occurs in postsynapse relationship: BFO:0000066 GO:0098794 ! occurs in postsynapse creation_date: 2017-09-11T17:09:17Z [Term] id: GO:0099171 name: presynaptic modulation of chemical synaptic transmission namespace: biological_process def: "Any process, acting in the presynapse that results in modulation of chemical synaptic transmission." [GOC:dos] is_a: GO:0050804 ! modulation of chemical synaptic transmission intersection_of: GO:0050804 ! modulation of chemical synaptic transmission intersection_of: BFO:0000066 GO:0098793 ! occurs in presynapse relationship: BFO:0000066 GO:0098793 ! occurs in presynapse creation_date: 2017-09-11T17:09:31Z [Term] id: GO:0099172 name: presynapse organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a presynapse." [GOC:dos] synonym: "presynapse development" EXACT [] synonym: "presynapse organisation" EXACT [] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0009987 ! cellular process intersection_of: RO:0002592 GO:0098793 ! results in organization of presynapse relationship: BFO:0000050 GO:0050808 ! part of synapse organization relationship: RO:0002592 GO:0098793 ! results in organization of presynapse [Term] id: GO:0099173 name: postsynapse organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a postsynapse." [GOC:dos] synonym: "postsynapse development" EXACT [] synonym: "postsynapse organisation" EXACT [] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0009987 ! cellular process intersection_of: RO:0002592 GO:0098794 ! results in organization of postsynapse relationship: BFO:0000050 GO:0050808 ! part of synapse organization relationship: RO:0002592 GO:0098794 ! results in organization of postsynapse [Term] id: GO:0099174 name: regulation of presynapse organization namespace: biological_process def: "Any process that modulates the physical form of a presynapse." [GOC:ai, GOC:dph, GOC:tb] synonym: "regulation of presynapse organisation" EXACT [GOC:mah] synonym: "regulation of presynapse structure" EXACT [] is_a: GO:0050807 ! regulation of synapse organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0099172 ! regulates (processual) presynapse organization relationship: RO:0002211 GO:0099172 ! regulates (processual) presynapse organization [Term] id: GO:0099175 name: regulation of postsynapse organization namespace: biological_process def: "Any process that modulates the physical form of a postsynapse." [GOC:ai, GOC:dph, GOC:tb] synonym: "regulation of postsynapse organisation" EXACT [GOC:mah] synonym: "regulation of postsynapse structure" EXACT [] is_a: GO:0050807 ! regulation of synapse organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0099173 ! regulates (processual) postsynapse organization relationship: RO:0002211 GO:0099173 ! regulates (processual) postsynapse organization [Term] id: GO:0099177 name: regulation of trans-synaptic signaling namespace: biological_process def: "Any process that modulates the frequency, rate or extent of trans-synaptic signaling." [GOC:dos] is_a: GO:0010646 ! regulation of cell communication is_a: GO:0023051 ! regulation of signaling intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0099537 ! regulates (processual) trans-synaptic signaling relationship: RO:0002211 GO:0099537 ! regulates (processual) trans-synaptic signaling [Term] id: GO:0099187 name: presynaptic cytoskeleton organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures and their associated proteins in the presynaptic cytoskeleton." [GOC:dos] is_a: GO:0007010 ! cytoskeleton organization intersection_of: GO:0009987 ! cellular process intersection_of: RO:0002592 GO:0099569 ! results in organization of presynaptic cytoskeleton relationship: BFO:0000050 GO:0099172 ! part of presynapse organization relationship: RO:0002592 GO:0099569 ! results in organization of presynaptic cytoskeleton creation_date: 2017-12-20T15:05:34Z [Term] id: GO:0099188 name: postsynaptic cytoskeleton organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising cytoskeletal filaments and their associated proteins in the postsynaptic cytoskeleton." [GOC:dos] is_a: GO:0007010 ! cytoskeleton organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0099571 ! results in organization of postsynaptic cytoskeleton relationship: BFO:0000050 GO:0099173 ! part of postsynapse organization relationship: RO:0002592 GO:0099571 ! results in organization of postsynaptic cytoskeleton creation_date: 2017-12-20T15:06:57Z [Term] id: GO:0099500 name: vesicle fusion to plasma membrane namespace: biological_process def: "Fusion of the membrane of a vesicle with the plasma membrane, thereby releasing its contents into the extracellular space." [GOC:aruk, GOC:bc, ISBN:0071120009, PMID:18618940] is_a: GO:0006906 ! vesicle fusion is_a: GO:0140029 ! exocytic process intersection_of: GO:0061025 ! membrane fusion intersection_of: BFO:0000050 GO:0006887 ! part of exocytosis intersection_of: RO:0012008 GO:0012506 ! results in fusion of vesicle membrane intersection_of: RO:0012008 GO:0098590 ! results in fusion of plasma membrane region relationship: RO:0012008 GO:0098590 ! results in fusion of plasma membrane region [Term] id: GO:0099501 name: exocytic vesicle membrane namespace: cellular_component def: "The lipid bilayer surrounding an exocytic vesicle." [GOC:dos] is_a: GO:0030658 ! transport vesicle membrane intersection_of: GO:0016020 ! membrane intersection_of: RO:0002007 GO:0070382 ! bounding layer of exocytic vesicle relationship: RO:0002007 GO:0070382 ! bounding layer of exocytic vesicle [Term] id: GO:0099503 name: secretory vesicle namespace: cellular_component def: "A cytoplasmic, membrane bound vesicle that is capable of fusing to the plasma membrane to release its contents into the extracellular space." [GOC:dos] is_a: GO:0031410 ! cytoplasmic vesicle intersection_of: GO:0031982 ! vesicle intersection_of: RO:0002215 GO:0099500 ! capable of vesicle fusion to plasma membrane relationship: RO:0002215 GO:0099500 ! capable of vesicle fusion to plasma membrane [Term] id: GO:0099512 name: supramolecular fiber namespace: cellular_component def: "A polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure." [GOC:dos] is_a: GO:0099081 ! supramolecular polymer intersection_of: GO:0099080 ! supramolecular complex intersection_of: RO:0000053 PATO:0002309 ! has characteristic fiber shaped intersection_of: RO:0000053 PATO:0015006 ! has characteristic polymeric relationship: RO:0000053 PATO:0002309 ! has characteristic fiber shaped [Term] id: GO:0099513 name: polymeric cytoskeletal fiber namespace: cellular_component def: "A component of the cytoskeleton consisting of a homo or heteropolymeric fiber constructed from an indeterminate number of protein subunits." [GOC:dos] is_a: GO:0099512 ! supramolecular fiber intersection_of: GO:0099512 ! supramolecular fiber intersection_of: BFO:0000050 GO:0005856 ! part of cytoskeleton intersection_of: RO:0000053 PATO:0015006 ! has characteristic polymeric relationship: BFO:0000050 GO:0005856 ! part of cytoskeleton [Term] id: GO:0099515 name: actin filament-based transport namespace: biological_process def: "The transport of organelles or other particles from one location in the cell to another along actin filaments." [GOC:dos, GOC:dph, GOC:mah, GOC:tb] is_a: GO:0030705 ! cytoskeleton-dependent intracellular transport intersection_of: GO:0046907 ! intracellular transport intersection_of: RO:0002341 GO:0005884 ! results in transport along actin filament relationship: RO:0002341 GO:0005884 ! results in transport along actin filament creation_date: 2009-05-27T10:56:08Z [Term] id: GO:0099518 name: vesicle cytoskeletal trafficking namespace: biological_process def: "The directed movement of a vesicle along a cytoskeletal fiber such as a microtubule or and actin filament, mediated by motor proteins." [GOC:ecd, GOC:rl] synonym: "cytoskeletal fiber-based vesicle localization" EXACT [GOC:rl] synonym: "vesicle cytoskeletal transport" EXACT [] is_a: GO:0030705 ! cytoskeleton-dependent intracellular transport is_a: GO:0051650 ! establishment of vesicle localization intersection_of: GO:0046907 ! intracellular transport intersection_of: RO:0002341 GO:0099513 ! results in transport along polymeric cytoskeletal fiber intersection_of: RO:0004009 GO:0031982 ! has primary input vesicle [Term] id: GO:0099531 name: presynaptic process involved in chemical synaptic transmission namespace: biological_process def: "The pathway leading to secretion of a neurotransmitter from the presynapse as part of synaptic transmission." [GOC:dos] is_a: GO:0050877 ! nervous system process intersection_of: GO:0050877 ! nervous system process intersection_of: BFO:0000050 GO:0007268 ! part of chemical synaptic transmission intersection_of: BFO:0000066 GO:0098793 ! occurs in presynapse relationship: BFO:0000050 GO:0007268 ! part of chemical synaptic transmission relationship: BFO:0000066 GO:0098793 ! occurs in presynapse [Term] id: GO:0099536 name: synaptic signaling namespace: biological_process def: "Cell-cell signaling to, from or within a synapse." [GOC:dos] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: BFO:0000066 GO:0045202 ! occurs in synapse relationship: BFO:0000066 GO:0045202 ! occurs in synapse relationship: RO:0002160 NCBITaxon:33208 ! only in taxon Metazoa relationship: RO:0002162 NCBITaxon:33208 {all_only="true"} ! in taxon Metazoa [Term] id: GO:0099537 name: trans-synaptic signaling namespace: biological_process def: "Cell-cell signaling in either direction across the synaptic cleft." [GOC:dos] is_a: GO:0099536 ! synaptic signaling [Term] id: GO:0099538 name: synaptic signaling via neuropeptide namespace: biological_process def: "Cell-cell signaling to or from a synapse, mediated by a peptide." [GOC:dos] is_a: GO:0099536 ! synaptic signaling intersection_of: GO:0099536 ! synaptic signaling intersection_of: RO:0002608 CHEBI:16670 ! process has causal agent peptide relationship: RO:0002608 CHEBI:16670 ! process has causal agent peptide [Term] id: GO:0099540 name: trans-synaptic signaling by neuropeptide namespace: biological_process def: "Cell-cell signaling between presynapse and postsynapse mediated by a peptide ligand crossing the synaptic cleft." [GOC:dos] is_a: GO:0099537 ! trans-synaptic signaling is_a: GO:0099538 ! synaptic signaling via neuropeptide intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: RO:0002608 CHEBI:16670 ! process has causal agent peptide [Term] id: GO:0099541 name: trans-synaptic signaling by lipid namespace: biological_process def: "Cell-cell signaling from post to pre-synapse, across the synaptic cleft, mediated by a lipid." [GOC:dos] is_a: GO:0099537 ! trans-synaptic signaling intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: RO:0002608 CHEBI:18059 ! process has causal agent lipid relationship: RO:0002608 CHEBI:18059 ! process has causal agent lipid [Term] id: GO:0099546 name: protein catabolic process, modulating synaptic transmission namespace: biological_process def: "Any protein degradation process, occurring at a presynapse, that regulates synaptic transmission." [GOC:dos, PMID:23083742] is_a: GO:0140246 ! protein catabolic process at synapse intersection_of: GO:0009056 ! catabolic process intersection_of: BFO:0000066 GO:0045202 ! occurs in synapse intersection_of: RO:0002211 GO:0007268 ! regulates (processual) chemical synaptic transmission intersection_of: RO:0004009 CHEBI:36080 ! has primary input protein relationship: RO:0002162 NCBITaxon:33208 {all_only="true"} ! in taxon Metazoa relationship: RO:0002211 GO:0007268 ! regulates (processual) chemical synaptic transmission [Term] id: GO:0099547 name: regulation of translation at synapse, modulating synaptic transmission namespace: biological_process def: "Any process that modulates synaptic transmission by regulating translation occurring at the synapse." [GOC:dos] is_a: GO:0050804 ! modulation of chemical synaptic transmission is_a: GO:0140243 ! regulation of translation at synapse intersection_of: GO:0065007 ! biological regulation intersection_of: BFO:0000066 GO:0045202 ! occurs in synapse intersection_of: RO:0002211 GO:0006412 ! regulates (processual) translation intersection_of: RO:0002211 GO:0007268 ! regulates (processual) chemical synaptic transmission relationship: RO:0002162 NCBITaxon:33208 {all_only="true"} ! in taxon Metazoa [Term] id: GO:0099550 name: trans-synaptic signaling, modulating synaptic transmission namespace: biological_process def: "Cell-cell signaling between presynapse and postsynapse, across the synaptic cleft, that modulates the synaptic transmission properties of the synapse." [GOC:dos] is_a: GO:0050804 ! modulation of chemical synaptic transmission is_a: GO:0099537 ! trans-synaptic signaling intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: RO:0002211 GO:0007268 ! regulates (processual) chemical synaptic transmission [Term] id: GO:0099551 name: trans-synaptic signaling by neuropeptide, modulating synaptic transmission namespace: biological_process def: "Cell-cell signaling between presynapse and postsynapse, via the vesicular release and reception of neuropeptide molecules, that modulates the synaptic transmission properties of the synapse." [GOC:dos] is_a: GO:0099540 ! trans-synaptic signaling by neuropeptide is_a: GO:0099550 ! trans-synaptic signaling, modulating synaptic transmission intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: RO:0002211 GO:0007268 ! regulates (processual) chemical synaptic transmission intersection_of: RO:0002608 CHEBI:16670 ! process has causal agent peptide [Term] id: GO:0099552 name: trans-synaptic signaling by lipid, modulating synaptic transmission namespace: biological_process def: "Cell-cell signaling between presynapse and postsynapse, via the release and reception of lipid molecules, that modulates the synaptic transmission properties of the synapse." [GOC:dos, PMID:21531987] is_a: GO:0099541 ! trans-synaptic signaling by lipid is_a: GO:0099550 ! trans-synaptic signaling, modulating synaptic transmission intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: RO:0002211 GO:0007268 ! regulates (processual) chemical synaptic transmission intersection_of: RO:0002608 CHEBI:18059 ! process has causal agent lipid [Term] id: GO:0099568 name: cytoplasmic region namespace: cellular_component def: "Any (proper) part of the cytoplasm of a single cell of sufficient size to still be considered cytoplasm." [GOC:dos] is_a: GO:0005737 ! cytoplasm intersection_of: GO:0005737 ! cytoplasm intersection_of: BFO:0000050 GO:0005737 ! part of cytoplasm relationship: BFO:0000050 GO:0005737 ! part of cytoplasm [Term] id: GO:0099569 name: presynaptic cytoskeleton namespace: cellular_component def: "The portion of the cytoskeleton contained within the presynapse." [GOC:dos] is_a: GO:0005856 ! cytoskeleton intersection_of: GO:0005856 ! cytoskeleton intersection_of: BFO:0000050 GO:0098793 ! part of presynapse relationship: BFO:0000050 GO:0098793 ! part of presynapse [Term] id: GO:0099571 name: postsynaptic cytoskeleton namespace: cellular_component def: "The portion of the cytoskeleton contained within the postsynapse." [GOC:dos, PMID:19889835] is_a: GO:0005856 ! cytoskeleton intersection_of: GO:0005856 ! cytoskeleton intersection_of: BFO:0000050 GO:0098794 ! part of postsynapse relationship: BFO:0000050 GO:0098794 ! part of postsynapse [Term] id: GO:0099574 name: regulation of protein catabolic process at synapse, modulating synaptic transmission namespace: biological_process def: "Any process that modulates synaptic transmission by regulating protein degradation at the synapse." [GOC:dos] is_a: GO:0050804 ! modulation of chemical synaptic transmission is_a: GO:0140250 ! regulation protein catabolic process at synapse intersection_of: GO:0065007 ! biological regulation intersection_of: BFO:0000066 GO:0045202 ! occurs in synapse intersection_of: RO:0002211 GO:0007268 ! regulates (processual) chemical synaptic transmission intersection_of: RO:0002211 GO:0009056 ! regulates (processual) catabolic process intersection_of: RO:0004009 CHEBI:36080 ! has primary input protein relationship: RO:0002162 NCBITaxon:33208 {all_only="true"} ! in taxon Metazoa [Term] id: GO:0099575 name: regulation of protein catabolic process at presynapse, modulating synaptic transmission namespace: biological_process def: "Any process that modulates synaptic transmission by regulating a catabolic process occurring at a presynapse." [GOC:dos] is_a: GO:0042176 ! regulation of protein catabolic process is_a: GO:0099171 ! presynaptic modulation of chemical synaptic transmission intersection_of: GO:0042176 ! regulation of protein catabolic process intersection_of: BFO:0000066 GO:0098793 ! occurs in presynapse intersection_of: RO:0002211 GO:0007268 ! regulates (processual) chemical synaptic transmission [Term] id: GO:0099576 name: regulation of protein catabolic process at postsynapse, modulating synaptic transmission namespace: biological_process def: "Any process that modulates synaptic transmission by regulating a catabolic process occurring at a postsynapse." [GOC:dos] is_a: GO:0042176 ! regulation of protein catabolic process is_a: GO:0099170 ! postsynaptic modulation of chemical synaptic transmission intersection_of: GO:0042176 ! regulation of protein catabolic process intersection_of: BFO:0000066 GO:0098794 ! occurs in postsynapse intersection_of: RO:0002211 GO:0007268 ! regulates (processual) chemical synaptic transmission [Term] id: GO:0099577 name: regulation of translation at presynapse, modulating synaptic transmission namespace: biological_process def: "Any process that modulates synaptic transmission by regulating translation occurring at the presynapse." [GOC:dos] is_a: GO:0099171 ! presynaptic modulation of chemical synaptic transmission is_a: GO:0099547 ! regulation of translation at synapse, modulating synaptic transmission is_a: GO:0140244 ! regulation of translation at presynapse intersection_of: GO:0065007 ! biological regulation intersection_of: BFO:0000066 GO:0098793 ! occurs in presynapse intersection_of: RO:0002211 GO:0006412 ! regulates (processual) translation intersection_of: RO:0002211 GO:0007268 ! regulates (processual) chemical synaptic transmission [Term] id: GO:0099578 name: regulation of translation at postsynapse, modulating synaptic transmission namespace: biological_process def: "Any process that modulates synaptic transmission by regulating translation occurring at the postsynapse." [GOC:dos] is_a: GO:0099170 ! postsynaptic modulation of chemical synaptic transmission is_a: GO:0099547 ! regulation of translation at synapse, modulating synaptic transmission is_a: GO:0140245 ! regulation of translation at postsynapse intersection_of: GO:0065007 ! biological regulation intersection_of: BFO:0000066 GO:0098794 ! occurs in postsynapse intersection_of: RO:0002211 GO:0006412 ! regulates (processual) translation intersection_of: RO:0002211 GO:0007268 ! regulates (processual) chemical synaptic transmission [Term] id: GO:0099632 name: protein transport within plasma membrane namespace: biological_process def: "A process in which protein is transported from one region of the plasma membrane to another." [GOC:dos] is_a: GO:0032594 ! protein transport within lipid bilayer intersection_of: GO:0006810 ! transport intersection_of: BFO:0000066 GO:0005886 ! occurs in plasma membrane intersection_of: RO:0004009 PR:000000001 ! has primary input protein relationship: BFO:0000066 GO:0005886 ! occurs in plasma membrane [Term] id: GO:0099640 name: axo-dendritic protein transport namespace: biological_process def: "The directed movement of proteins along microtubules in neuron projections." [ISBN:0815316194] is_a: GO:0008088 ! axo-dendritic transport is_a: GO:0098840 ! protein transport along microtubule intersection_of: GO:0046907 ! intracellular transport intersection_of: BFO:0000066 GO:0043005 ! occurs in neuron projection intersection_of: RO:0002341 GO:0005874 ! results in transport along microtubule intersection_of: RO:0004009 PR:000000001 ! has primary input protein [Term] id: GO:0099643 name: signal release from synapse namespace: biological_process def: "Any signal release from a synapse." [GOC:dos] is_a: GO:0023061 ! signal release intersection_of: GO:0023061 ! signal release intersection_of: BFO:0000066 GO:0045202 ! occurs in synapse relationship: BFO:0000050 GO:0099536 ! part of synaptic signaling relationship: RO:0002160 NCBITaxon:33208 ! only in taxon Metazoa relationship: RO:0002162 NCBITaxon:33208 {all_only="true"} ! in taxon Metazoa [Term] id: GO:0099738 name: cell cortex region namespace: cellular_component def: "The complete extent of cell cortex that underlies some some region of the plasma membrane." [GOC:dos] synonym: "perimembrane region" EXACT [] is_a: GO:0005938 ! cell cortex is_a: GO:0099568 ! cytoplasmic region intersection_of: GO:0005938 ! cell cortex intersection_of: BFO:0000050 GO:0005938 ! part of cell cortex relationship: BFO:0000050 GO:0005938 ! part of cell cortex [Term] id: GO:0100001 name: regulation of skeletal muscle contraction by action potential namespace: biological_process def: "Any action potential process that regulates skeletal muscle contraction." [GOC:cjm, GOC:obol] is_a: BFO:0000015 ! process is_a: GO:0001508 ! action potential intersection_of: GO:0001508 ! action potential intersection_of: RO:0002211 GO:0003009 ! regulates (processual) skeletal muscle contraction relationship: RO:0002211 GO:0003009 ! regulates (processual) skeletal muscle contraction creation_date: 2015-04-02T04:13:19Z [Term] id: GO:0101023 name: vascular endothelial cell proliferation namespace: biological_process def: "The multiplication or reproduction of blood vessel endothelial cells, resulting in the expansion of a cell population." [GOC:BHF, GOC:BHF_telomere, GOC:nc, PMID:23201774] is_a: GO:0001935 ! endothelial cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000071 ! acts on population of blood vessel endothelial cell relationship: RO:0012003 CL:0000071 ! acts on population of blood vessel endothelial cell [Term] id: GO:0101024 name: mitotic nuclear membrane organization namespace: biological_process def: "A mitotic cell cycle process which results in the assembly, arrangement, or disassembly of the nuclear inner or outer membrane during mitosis." [GOC:vw, PMID:15147872] synonym: "nuclear membrane organization involved in mitotic nuclear division" EXACT [] is_a: GO:0071763 ! nuclear membrane organization is_a: GO:1903047 ! mitotic cell cycle process intersection_of: GO:0071763 ! nuclear membrane organization intersection_of: BFO:0000050 GO:0140014 ! part of mitotic nuclear division relationship: BFO:0000050 GO:0140014 ! part of mitotic nuclear division relationship: RO:0002160 NCBITaxon:2759 ! only in taxon Eukaryota relationship: RO:0002162 NCBITaxon:2759 {all_only="true"} ! in taxon Eukaryota [Term] id: GO:0101025 name: nuclear membrane biogenesis namespace: biological_process def: "The process in which a nuclear membrane is synthesized, aggregates, and bonds together." [GOC:vw] is_a: GO:0044091 ! membrane biogenesis intersection_of: GO:0044085 ! cellular component biogenesis intersection_of: RO:0004008 GO:0031965 ! has primary output nuclear membrane relationship: BFO:0000050 GO:0071763 ! part of nuclear membrane organization relationship: RO:0004008 GO:0031965 ! has primary output nuclear membrane [Term] id: GO:0106027 name: neuron projection organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a neuron, e.g. an axon, or a dendrite." [GOC:aruk, GOC:bc, PMID:11585923] is_a: GO:0120036 ! plasma membrane bounded cell projection organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0043005 ! results in organization of neuron projection relationship: RO:0002592 GO:0043005 ! results in organization of neuron projection creation_date: 2017-06-23T18:30:18Z [Term] id: GO:0106214 name: regulation of vesicle fusion with Golgi apparatus namespace: biological_process def: "Any process that modulates the frequency, rate or extent of vesicle fusion with Golgi apparatus." [GOC:se, PMID:26195667] is_a: GO:0031338 ! regulation of vesicle fusion is_a: GO:1903358 ! regulation of Golgi organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048280 ! regulates (processual) vesicle fusion with Golgi apparatus relationship: RO:0002211 GO:0048280 ! regulates (processual) vesicle fusion with Golgi apparatus creation_date: 2019-06-27T15:12:22Z [Term] id: GO:0106215 name: negative regulation of vesicle fusion with Golgi apparatus namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of vesicle fustion with Golgi apparatus." [GOC:se, PMID:26195667] is_a: GO:0031339 ! negative regulation of vesicle fusion is_a: GO:0106214 ! regulation of vesicle fusion with Golgi apparatus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048280 ! negatively regulates vesicle fusion with Golgi apparatus relationship: RO:0002212 GO:0048280 ! negatively regulates vesicle fusion with Golgi apparatus creation_date: 2019-06-27T15:17:17Z [Term] id: GO:0106216 name: positive regulation of vesicle fusion with Golgi apparatus namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of vesicle fusion with Golgi apparatus." [GOC:se, PMID:26195667] is_a: GO:0031340 ! positive regulation of vesicle fusion is_a: GO:0106214 ! regulation of vesicle fusion with Golgi apparatus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0048280 ! positively regulates vesicle fusion with Golgi apparatus relationship: RO:0002213 GO:0048280 ! positively regulates vesicle fusion with Golgi apparatus creation_date: 2019-06-27T15:20:59Z [Term] id: GO:0110011 name: regulation of basement membrane organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the assembly, disassembly or arrangement of constituent parts of the basement membrane." [GOC:ha, PMID:27404358] is_a: GO:1903053 ! regulation of extracellular matrix organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0071711 ! regulates (processual) basement membrane organization relationship: RO:0002211 GO:0071711 ! regulates (processual) basement membrane organization [Term] id: GO:0110020 name: regulation of actomyosin structure organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin." [GOC:lf, PMID:22790195] is_a: GO:0032956 ! regulation of actin cytoskeleton organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0031032 ! regulates (processual) actomyosin structure organization relationship: RO:0002211 GO:0031032 ! regulates (processual) actomyosin structure organization creation_date: 2017-06-20T19:28:58Z [Term] id: GO:0110021 name: cardiac muscle myoblast proliferation namespace: biological_process def: "The multiplication or reproduction of cardiac muscle myoblasts, resulting in the expansion of a cardiac muscle myoblast cell population. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:26512644] is_a: GO:0051450 ! myoblast proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000513 ! acts on population of cardiac muscle myoblast relationship: RO:0012003 CL:0000513 ! acts on population of cardiac muscle myoblast creation_date: 2017-06-29T14:35:24Z [Term] id: GO:0110022 name: regulation of cardiac muscle myoblast proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac muscle myoblast proliferation." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:26512644] is_a: GO:2000291 ! regulation of myoblast proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0110021 ! regulates (processual) cardiac muscle myoblast proliferation relationship: RO:0002211 GO:0110021 ! regulates (processual) cardiac muscle myoblast proliferation creation_date: 2017-06-29T15:11:47Z [Term] id: GO:0110023 name: negative regulation of cardiac muscle myoblast proliferation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle myoblast proliferation." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:26512644] is_a: GO:0110022 ! regulation of cardiac muscle myoblast proliferation is_a: GO:2000818 ! negative regulation of myoblast proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0110021 ! negatively regulates cardiac muscle myoblast proliferation relationship: RO:0002212 GO:0110021 ! negatively regulates cardiac muscle myoblast proliferation creation_date: 2017-06-29T15:18:30Z [Term] id: GO:0110024 name: positive regulation of cardiac muscle myoblast proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cardiac muscle myoblast proliferation." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:26512644] is_a: GO:0110022 ! regulation of cardiac muscle myoblast proliferation is_a: GO:2000288 ! positive regulation of myoblast proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0110021 ! positively regulates cardiac muscle myoblast proliferation relationship: RO:0002213 GO:0110021 ! positively regulates cardiac muscle myoblast proliferation creation_date: 2017-06-29T15:24:16Z [Term] id: GO:0110053 name: regulation of actin filament organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of actin filament organization." [GOC:kmv] is_a: GO:0032956 ! regulation of actin cytoskeleton organization is_a: GO:1902903 ! regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007015 ! regulates (processual) actin filament organization relationship: RO:0002211 GO:0007015 ! regulates (processual) actin filament organization creation_date: 2017-09-20T19:52:57Z [Term] id: GO:0110057 name: regulation of blood vessel endothelial cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of blood vessel endothelial cell differentiation." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:23072816] is_a: GO:0045601 ! regulation of endothelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060837 ! regulates (processual) blood vessel endothelial cell differentiation relationship: RO:0002211 GO:0060837 ! regulates (processual) blood vessel endothelial cell differentiation creation_date: 2017-10-23T14:32:09Z [Term] id: GO:0110058 name: positive regulation of blood vessel endothelial cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of blood vessel endothelial cell differentiation." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:23072816] is_a: GO:0045603 ! positive regulation of endothelial cell differentiation is_a: GO:0110057 ! regulation of blood vessel endothelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060837 ! positively regulates blood vessel endothelial cell differentiation relationship: RO:0002213 GO:0060837 ! positively regulates blood vessel endothelial cell differentiation creation_date: 2017-10-23T14:38:19Z [Term] id: GO:0110059 name: negative regulation of blood vessel endothelial cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel endothelial cell differentiation." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:23072816] is_a: GO:0045602 ! negative regulation of endothelial cell differentiation is_a: GO:0110057 ! regulation of blood vessel endothelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060837 ! negatively regulates blood vessel endothelial cell differentiation relationship: RO:0002212 GO:0060837 ! negatively regulates blood vessel endothelial cell differentiation creation_date: 2017-10-23T14:47:29Z [Term] id: GO:0110077 name: vesicle-mediated intercellular transport namespace: biological_process def: "A cellular transport process in which transported substances are moved in extracellular vesicles between cells; transported substances are enclosed in the vesicle lumen or located in the extracellular vesicle membrane." [GOC:sp, PMID:29328915, PMID:29328916] is_a: GO:0010496 ! intercellular transport is_a: GO:0016192 ! vesicle-mediated transport intersection_of: GO:0010496 ! intercellular transport intersection_of: RO:0002608 GO:1903561 ! process has causal agent extracellular vesicle relationship: RO:0002608 GO:1903561 ! process has causal agent extracellular vesicle creation_date: 2018-01-29T14:46:52Z [Term] id: GO:0110079 name: regulation of placenta blood vessel development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of placenta blood vessel development." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:27748453] is_a: GO:1901342 ! regulation of vasculature development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060674 ! regulates (processual) placenta blood vessel development relationship: RO:0002211 GO:0060674 ! regulates (processual) placenta blood vessel development creation_date: 2018-02-01T14:49:12Z [Term] id: GO:0110080 name: positive regulation of placenta blood vessel development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of placenta blood vessel development." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:27748453] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0110079 ! regulation of placenta blood vessel development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060674 ! positively regulates placenta blood vessel development relationship: RO:0002213 GO:0060674 ! positively regulates placenta blood vessel development creation_date: 2018-02-01T14:55:30Z [Term] id: GO:0110081 name: negative regulation of placenta blood vessel development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of placenta blood vessel development." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:27748453] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0110079 ! regulation of placenta blood vessel development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060674 ! negatively regulates placenta blood vessel development relationship: RO:0002212 GO:0060674 ! negatively regulates placenta blood vessel development creation_date: 2018-02-01T15:01:11Z [Term] id: GO:0110110 name: positive regulation of animal organ morphogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of animal organ morphogenesis." [GOC:kmv] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:2000027 ! regulation of animal organ morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0009887 ! positively regulates animal organ morphogenesis relationship: RO:0002213 GO:0009887 ! positively regulates animal organ morphogenesis creation_date: 2018-07-05T14:10:14Z [Term] id: GO:0110111 name: negative regulation of animal organ morphogenesis namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of animal organ morphogenesis." [GOC:kmv] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:2000027 ! regulation of animal organ morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0009887 ! negatively regulates animal organ morphogenesis relationship: RO:0002212 GO:0009887 ! negatively regulates animal organ morphogenesis creation_date: 2018-07-05T14:25:21Z [Term] id: GO:0110112 name: regulation of lipid transporter activity namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of lipid transporter activity." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:27365390] is_a: GO:0032368 ! regulation of lipid transport is_a: GO:0032409 ! regulation of transporter activity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0005319 ! regulates (processual) lipid transporter activity relationship: RO:0002211 GO:0005319 ! regulates (processual) lipid transporter activity creation_date: 2018-07-06T18:53:55Z [Term] id: GO:0110113 name: positive regulation of lipid transporter activity namespace: biological_process def: "Any process that increases the frequency, rate, or extent of lipid transporter activity." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:27365390] is_a: GO:0032370 ! positive regulation of lipid transport is_a: GO:0032411 ! positive regulation of transporter activity is_a: GO:0110112 ! regulation of lipid transporter activity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0005319 ! positively regulates lipid transporter activity relationship: RO:0002213 GO:0005319 ! positively regulates lipid transporter activity creation_date: 2018-07-06T19:14:13Z [Term] id: GO:0110114 name: negative regulation of lipid transporter activity namespace: biological_process def: "Any process that decreases the frequency, rate, or extent of lipid transporter activity." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:27365390] is_a: GO:0032369 ! negative regulation of lipid transport is_a: GO:0032410 ! negative regulation of transporter activity is_a: GO:0110112 ! regulation of lipid transporter activity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0005319 ! negatively regulates lipid transporter activity relationship: RO:0002212 GO:0005319 ! negatively regulates lipid transporter activity creation_date: 2018-07-06T19:21:44Z [Term] id: GO:0110116 name: regulation of compound eye photoreceptor cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of compound eye photoreceptor cell differentiation." [GOC:ha, PMID:16377567] is_a: GO:0046532 ! regulation of photoreceptor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001751 ! regulates (processual) compound eye photoreceptor cell differentiation relationship: RO:0002211 GO:0001751 ! regulates (processual) compound eye photoreceptor cell differentiation creation_date: 2018-07-16T18:08:49Z [Term] id: GO:0110117 name: positive regulation of compound eye photoreceptor cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor cell differentiation." [GOC:ha, PMID:16377567] is_a: GO:0046534 ! positive regulation of photoreceptor cell differentiation is_a: GO:0110116 ! regulation of compound eye photoreceptor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001751 ! positively regulates compound eye photoreceptor cell differentiation relationship: RO:0002213 GO:0001751 ! positively regulates compound eye photoreceptor cell differentiation creation_date: 2018-07-16T18:13:28Z [Term] id: GO:0110118 name: negative regulation of compound eye photoreceptor cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of compound eye photoreceptor cell differentiation." [GOC:ha, PMID:16377567] is_a: GO:0046533 ! negative regulation of photoreceptor cell differentiation is_a: GO:0110116 ! regulation of compound eye photoreceptor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001751 ! negatively regulates compound eye photoreceptor cell differentiation relationship: RO:0002212 GO:0001751 ! negatively regulates compound eye photoreceptor cell differentiation creation_date: 2018-07-16T18:15:52Z [Term] id: GO:0110122 name: myotube cell migration namespace: biological_process def: "The orderly movement of a myotube cell from one site to another, often during the development of a multicellular organism. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate, and fuse." [GOC:ha, PMID:29122742] is_a: GO:0014812 ! muscle cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0002372 ! results in movement of myotube relationship: RO:0002565 CL:0002372 ! results in movement of myotube creation_date: 2018-08-22T20:58:09Z [Term] id: GO:0110123 name: regulation of myotube cell migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of myotube cell migration." [GOC:ha, PMID:29122742] is_a: GO:0030334 ! regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0110122 ! regulates (processual) myotube cell migration relationship: RO:0002211 GO:0110122 ! regulates (processual) myotube cell migration creation_date: 2018-08-22T21:06:53Z [Term] id: GO:0110124 name: positive regulation of myotube cell migration namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of myotube cell migration." [GOC:ha, PMID:29122742] is_a: GO:0030335 ! positive regulation of cell migration is_a: GO:0110123 ! regulation of myotube cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0110122 ! positively regulates myotube cell migration relationship: RO:0002213 GO:0110122 ! positively regulates myotube cell migration creation_date: 2018-08-22T21:09:38Z [Term] id: GO:0110125 name: negative regulation of myotube cell migration namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of myotube cell migration." [GOC:ha, PMID:29122742] is_a: GO:0030336 ! negative regulation of cell migration is_a: GO:0110123 ! regulation of myotube cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0110122 ! negatively regulates myotube cell migration relationship: RO:0002212 GO:0110122 ! negatively regulates myotube cell migration creation_date: 2018-08-22T21:12:47Z [Term] id: GO:0110165 name: cellular anatomical entity namespace: cellular_component def: "A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex." [GOC:kmv] is_a: CARO:0000000 ! anatomical entity is_a: GO:0005575 ! cellular_component is_a: UBERON:0000061 ! anatomical structure creation_date: 2019-08-12T18:01:37Z [Term] id: GO:0120025 name: plasma membrane bounded cell projection namespace: cellular_component def: "A prolongation or process extending from a cell and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon." [GOC:krc] is_a: GO:0042995 ! cell projection intersection_of: GO:0042995 ! cell projection intersection_of: BFO:0000051 GO:0098590 ! has part plasma membrane region relationship: BFO:0000051 GO:0098590 ! has part plasma membrane region creation_date: 2017-03-21T17:26:07Z [Term] id: GO:0120031 name: plasma membrane bounded cell projection assembly namespace: biological_process def: "Formation of a prolongation or process extending and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon." [GOC:krc] is_a: GO:0030031 ! cell projection assembly is_a: GO:0120036 ! plasma membrane bounded cell projection organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0120025 ! results in assembly of plasma membrane bounded cell projection relationship: RO:0002588 GO:0120025 ! results in assembly of plasma membrane bounded cell projection creation_date: 2017-04-24T23:56:08Z [Term] id: GO:0120032 name: regulation of plasma membrane bounded cell projection assembly namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of plasma membrane bounded cell projection assembly." [GOC:krc] is_a: GO:0060491 ! regulation of cell projection assembly is_a: GO:0120035 ! regulation of plasma membrane bounded cell projection organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0120031 ! regulates (processual) plasma membrane bounded cell projection assembly relationship: RO:0002211 GO:0120031 ! regulates (processual) plasma membrane bounded cell projection assembly creation_date: 2017-04-26T04:27:04Z [Term] id: GO:0120033 name: negative regulation of plasma membrane bounded cell projection assembly namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane bounded cell projection assembly." [GOC:krc] is_a: GO:0031345 ! negative regulation of cell projection organization is_a: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0120031 ! negatively regulates plasma membrane bounded cell projection assembly relationship: RO:0002212 GO:0120031 ! negatively regulates plasma membrane bounded cell projection assembly creation_date: 2017-04-26T04:34:31Z [Term] id: GO:0120034 name: positive regulation of plasma membrane bounded cell projection assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of plasma membrane bounded cell projection assembly." [GOC:krc] is_a: GO:0031346 ! positive regulation of cell projection organization is_a: GO:0044089 ! positive regulation of cellular component biogenesis is_a: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0120031 ! positively regulates plasma membrane bounded cell projection assembly relationship: RO:0002213 GO:0120031 ! positively regulates plasma membrane bounded cell projection assembly creation_date: 2017-04-26T04:34:45Z [Term] id: GO:0120035 name: regulation of plasma membrane bounded cell projection organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of plasma membrane bounded cell projections." [GOC:krc] is_a: GO:0031344 ! regulation of cell projection organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0120036 ! regulates (processual) plasma membrane bounded cell projection organization relationship: RO:0002211 GO:0120036 ! regulates (processual) plasma membrane bounded cell projection organization creation_date: 2017-04-26T16:02:06Z [Term] id: GO:0120036 name: plasma membrane bounded cell projection organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasma membrane bounded prolongation or process extending from a cell, e.g. a cilium or axon." [GOC:krc] is_a: GO:0030030 ! cell projection organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0120025 ! results in organization of plasma membrane bounded cell projection relationship: RO:0002592 GO:0120025 ! results in organization of plasma membrane bounded cell projection creation_date: 2017-04-26T16:07:02Z [Term] id: GO:0120039 name: plasma membrane bounded cell projection morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a plasma membrane bounded cell projection are generated and organized." [GOC:krc] is_a: GO:0048858 ! cell projection morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 GO:0120025 ! results in morphogenesis of plasma membrane bounded cell projection relationship: RO:0002298 GO:0120025 ! results in morphogenesis of plasma membrane bounded cell projection creation_date: 2017-04-28T23:39:37Z [Term] id: GO:0120111 name: neuron projection cytoplasm namespace: cellular_component def: "All of the contents of a plasma membrane bounded neuron projection, excluding the plasma membrane surrounding the projection." [GOC:ha] is_a: GO:0032838 ! plasma membrane bounded cell projection cytoplasm intersection_of: GO:0005737 ! cytoplasm intersection_of: BFO:0000050 GO:0043005 ! part of neuron projection relationship: BFO:0000050 GO:0043005 ! part of neuron projection creation_date: 2017-11-01T18:58:12Z [Term] id: GO:0120158 name: positive regulation of collagen catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix." [GOC:dph, GOC:tb] synonym: "positive regulation of collagen breakdown" EXACT [GOC:dph, GOC:tb] synonym: "positive regulation of collagen catabolism" EXACT [GOC:dph, GOC:tb] synonym: "positive regulation of collagen degradation" EXACT [GOC:dph, GOC:tb] synonym: "up regulation of collagen catabolic process" EXACT [GOC:dph, GOC:tb] synonym: "up-regulation of collagen catabolic process" EXACT [GOC:dph, GOC:tb] synonym: "upregulation of collagen catabolic process" EXACT [GOC:dph, GOC:tb] is_a: GO:0009896 ! positive regulation of catabolic process is_a: GO:0010710 ! regulation of collagen catabolic process is_a: GO:0010714 ! positive regulation of collagen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030574 ! positively regulates collagen catabolic process relationship: RO:0002213 GO:0030574 ! positively regulates collagen catabolic process creation_date: 2018-05-11T16:31:42Z [Term] id: GO:0120178 name: steroid hormone biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of any steroid hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone." [GOC:krc, GOC:nln] is_a: GO:0006694 ! steroid biosynthetic process intersection_of: GO:0006694 ! steroid biosynthetic process intersection_of: RO:0004008 CHEBI:26764 ! has primary output steroid hormone relationship: RO:0004008 CHEBI:26764 ! has primary output steroid hormone creation_date: 2019-05-20T22:34:00Z [Term] id: GO:0120186 name: negative regulation of protein localization to chromatin namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to chromatin." [PMID:20889714, PMID:29899453] synonym: "negative regulation of protein localisation to chromatin" EXACT [GOC:krc] is_a: GO:1903828 ! negative regulation of protein localization is_a: GO:1905634 ! regulation of protein localization to chromatin intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0071168 ! negatively regulates protein localization to chromatin relationship: RO:0002212 GO:0071168 ! negatively regulates protein localization to chromatin creation_date: 2018-07-14T00:19:32Z [Term] id: GO:0120187 name: positive regulation of protein localization to chromatin namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein localization to chromatin." [PMID:20889714, PMID:29899453] synonym: "positive regulation of protein localisation to chromatin" EXACT [GOC:krc] is_a: GO:1903829 ! positive regulation of protein localization is_a: GO:1905634 ! regulation of protein localization to chromatin intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0071168 ! positively regulates protein localization to chromatin relationship: RO:0002213 GO:0071168 ! positively regulates protein localization to chromatin creation_date: 2018-07-14T00:21:28Z [Term] id: GO:0120188 name: regulation of bile acid secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:22767443] is_a: GO:0051046 ! regulation of secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0032782 ! regulates (processual) bile acid secretion relationship: RO:0002211 GO:0032782 ! regulates (processual) bile acid secretion creation_date: 2018-07-16T22:28:58Z [Term] id: GO:0120189 name: positive regulation of bile acid secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:22767443] is_a: GO:0051047 ! positive regulation of secretion is_a: GO:0120188 ! regulation of bile acid secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0032782 ! positively regulates bile acid secretion relationship: RO:0002213 GO:0032782 ! positively regulates bile acid secretion creation_date: 2018-07-16T22:36:17Z [Term] id: GO:0120190 name: negative regulation of bile acid secretion namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:22767443] is_a: GO:0051048 ! negative regulation of secretion is_a: GO:0120188 ! regulation of bile acid secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0032782 ! negatively regulates bile acid secretion relationship: RO:0002212 GO:0032782 ! negatively regulates bile acid secretion creation_date: 2018-07-16T22:38:34Z [Term] id: GO:0120222 name: regulation of blastocyst development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of blastocyst development." [GOC:krc, PMID:29593216] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001824 ! regulates (processual) blastocyst development relationship: RO:0002211 GO:0001824 ! regulates (processual) blastocyst development creation_date: 2020-02-17T19:59:20Z [Term] id: GO:0120229 name: protein localization to motile cilium namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within a motile cilium." [GOC:krc, PMID:27486780] is_a: GO:0061512 ! protein localization to cilium intersection_of: GO:0008104 ! protein localization intersection_of: RO:0002339 GO:0031514 ! has target end location motile cilium relationship: RO:0002339 GO:0031514 ! has target end location motile cilium creation_date: 2020-06-05T23:43:04Z [Term] id: GO:0120305 name: regulation of pigmentation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the deposition or modulates the distribution of coloring matter in an organism." [GOC:krc] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0043473 ! regulates (processual) pigmentation relationship: RO:0002211 GO:0043473 ! regulates (processual) pigmentation creation_date: 2021-02-09T19:37:35Z [Term] id: GO:0120316 name: sperm flagellum assembly namespace: biological_process def: "The assembly and organization of the sperm flagellum, the microtubule-based axoneme and associated structures that are part of a sperm flagellum (or cilium)." [GOC:krc, PMID:32791035] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0044458 ! motile cilium assembly intersection_of: GO:0044458 ! motile cilium assembly intersection_of: BFO:0000066 CL:0000019 ! occurs in sperm relationship: BFO:0000050 GO:0007286 ! part of spermatid development relationship: BFO:0000050 GO:0030317 ! part of flagellated sperm motility relationship: BFO:0000066 CL:0000019 ! occurs in sperm creation_date: 2021-04-29T01:27:27Z [Term] id: GO:0120331 name: endothelial tube formation namespace: biological_process def: "The developmental process pertaining to the initial formation of an endothelial tube." [GOC:sl, PMID:23239824] is_a: GO:0072175 ! epithelial tube formation intersection_of: GO:0035148 ! tube formation intersection_of: RO:0002297 UBERON:0003915 ! results in formation of anatomical entity endothelial tube relationship: BFO:0000050 GO:0061154 ! part of endothelial tube morphogenesis relationship: RO:0002297 UBERON:0003915 ! results in formation of anatomical entity endothelial tube creation_date: 2022-05-25T16:17:59Z [Term] id: GO:0140013 name: meiotic nuclear division namespace: biological_process def: "One of the two nuclear divisions that occur as part of the meiotic cell cycle." [PMID:9334324] synonym: "meiosis" EXACT [] is_a: GO:0000280 ! nuclear division is_a: GO:1903046 ! meiotic cell cycle process intersection_of: GO:0000280 ! nuclear division intersection_of: BFO:0000050 GO:0051321 ! part of meiotic cell cycle creation_date: 2017-03-23T09:40:00Z [Term] id: GO:0140014 name: mitotic nuclear division namespace: biological_process def: "A mitotic cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell." [ISBN:0198547684] synonym: "mitosis" EXACT [] is_a: GO:0000280 ! nuclear division is_a: GO:1903047 ! mitotic cell cycle process intersection_of: GO:0000280 ! nuclear division intersection_of: BFO:0000050 GO:0000278 ! part of mitotic cell cycle creation_date: 2017-03-23T14:44:23Z [Term] id: GO:0140029 name: exocytic process namespace: biological_process def: "The cellular processes that contribute to exocytosis." [Wikipedia:Exocytosis] is_a: GO:0009987 ! cellular process intersection_of: GO:0009987 ! cellular process intersection_of: BFO:0000050 GO:0006887 ! part of exocytosis relationship: BFO:0000050 GO:0006887 ! part of exocytosis creation_date: 2017-05-15T13:20:45Z [Term] id: GO:0140056 name: organelle localization by membrane tethering namespace: biological_process def: "The process by which an organelle membrane interacts with another membrane via molecular tethers that physically bridge the two membranes and attach them to each other." [PMID:27875684] is_a: GO:0022406 ! membrane docking is_a: GO:0051640 ! organelle localization creation_date: 2017-06-27T09:58:51Z [Term] id: GO:0140096 name: catalytic activity, acting on a protein namespace: molecular_function def: "Catalytic activity that acts to modify a protein." [GOC:molecular_function_refactoring, GOC:pdt] is_a: GO:0003824 ! catalytic activity intersection_of: GO:0003824 ! catalytic activity intersection_of: RO:0004009 PR:000000001 ! has primary input protein relationship: RO:0004009 PR:000000001 ! has primary input protein creation_date: 2017-09-14T10:32:59Z [Term] id: GO:0140097 name: catalytic activity, acting on DNA namespace: molecular_function def: "Catalytic activity that acts to modify DNA." [GOC:molecular_function_refactoring, GOC:pdt] is_a: GO:0140640 ! catalytic activity, acting on a nucleic acid intersection_of: GO:0003824 ! catalytic activity intersection_of: RO:0004009 CHEBI:16991 ! has primary input deoxyribonucleic acid relationship: RO:0004009 CHEBI:16991 ! has primary input deoxyribonucleic acid creation_date: 2017-09-14T12:03:51Z [Term] id: GO:0140098 name: catalytic activity, acting on RNA namespace: molecular_function def: "Catalytic activity that acts to modify RNA, driven by ATP hydrolysis." [GOC:molecular_function_refactoring, GOC:pdt] is_a: GO:0140640 ! catalytic activity, acting on a nucleic acid intersection_of: GO:0003824 ! catalytic activity intersection_of: RO:0004009 CHEBI:33697 ! has primary input ribonucleic acid relationship: RO:0004009 CHEBI:33697 ! has primary input ribonucleic acid creation_date: 2017-09-14T12:05:21Z [Term] id: GO:0140103 name: catalytic activity, acting on a glycoprotein namespace: molecular_function def: "Catalysis of a biochemical reaction at physiological temperatures in which one of the substrates is a glycoprotein." [GOC:molecular_function_refactoring, GOC:pdt] is_a: GO:0003824 ! catalytic activity intersection_of: GO:0003824 ! catalytic activity intersection_of: RO:0004009 CHEBI:17089 ! has primary input glycoprotein relationship: RO:0004009 CHEBI:17089 ! has primary input glycoprotein creation_date: 2017-09-15T19:27:54Z [Term] id: GO:0140112 name: extracellular vesicle biogenesis namespace: biological_process def: "The assembly and secretion a set of components to form an extracellular vesicule, a membrane-bounded vesicle that is released into the extracellular region. Extracellular vesicles include exosomes, microvesicles and apoptotic bodies, based on the mechanism by which they are released from cells and differentiated based on their size and content." [PMID:28736435] synonym: "extracellular vesicle assembly" EXACT [] is_a: GO:0044085 ! cellular component biogenesis creation_date: 2017-10-23T11:53:42Z [Term] id: GO:0140236 name: translation at presynapse namespace: biological_process def: "Translation that occurs at the presynapse." [PMID:27321671] is_a: GO:0140241 ! translation at synapse intersection_of: GO:0006412 ! translation intersection_of: BFO:0000066 GO:0098793 ! occurs in presynapse relationship: BFO:0000066 GO:0098793 ! occurs in presynapse creation_date: 2018-07-13T13:00:33Z [Term] id: GO:0140237 name: translation at presynapse, modulating chemical synaptic transmission namespace: biological_process def: "Translation that occurs at the presynapse, and that modulates chemical synaptic transmission." [PMID:27321671] is_a: GO:0140236 ! translation at presynapse intersection_of: GO:0006412 ! translation intersection_of: BFO:0000066 GO:0098793 ! occurs in presynapse intersection_of: RO:0002211 GO:0007268 ! regulates (processual) chemical synaptic transmission relationship: RO:0002211 GO:0007268 ! regulates (processual) chemical synaptic transmission creation_date: 2018-07-13T13:07:23Z [Term] id: GO:0140238 name: presynaptic endocytosis namespace: biological_process def: "A vesicle-mediated transport process in which the presynapse take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle." [PMID:24719103] is_a: GO:0006897 ! endocytosis is_a: GO:0051649 ! establishment of localization in cell is_a: GO:0099003 ! vesicle-mediated transport in synapse intersection_of: GO:0006897 ! endocytosis intersection_of: BFO:0000066 GO:0098793 ! occurs in presynapse relationship: BFO:0000066 GO:0098793 ! occurs in presynapse creation_date: 2018-07-15T07:33:55Z [Term] id: GO:0140239 name: postsynaptic endocytosis namespace: biological_process def: "A vesicle-mediated transport process in which the postsynapse take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle." [PMID:12839988] is_a: GO:0006897 ! endocytosis is_a: GO:0051649 ! establishment of localization in cell is_a: GO:0099003 ! vesicle-mediated transport in synapse intersection_of: GO:0006897 ! endocytosis intersection_of: BFO:0000066 GO:0098794 ! occurs in postsynapse relationship: BFO:0000066 GO:0098794 ! occurs in postsynapse creation_date: 2018-07-15T07:38:27Z [Term] id: GO:0140241 name: translation at synapse namespace: biological_process def: "Translation that occurs at the synapse." [PMID:23083742] is_a: GO:0006412 ! translation intersection_of: GO:0006412 ! translation intersection_of: BFO:0000066 GO:0045202 ! occurs in synapse relationship: BFO:0000066 GO:0045202 ! occurs in synapse relationship: RO:0002160 NCBITaxon:33208 ! only in taxon Metazoa relationship: RO:0002162 NCBITaxon:33208 {all_only="true"} ! in taxon Metazoa creation_date: 2018-07-15T09:23:12Z [Term] id: GO:0140242 name: translation at postsynapse namespace: biological_process def: "Translation that occurs at the postsynapse." [PMID:20427644] is_a: GO:0140241 ! translation at synapse intersection_of: GO:0006412 ! translation intersection_of: BFO:0000066 GO:0098794 ! occurs in postsynapse relationship: BFO:0000066 GO:0098794 ! occurs in postsynapse creation_date: 2018-07-15T09:26:27Z [Term] id: GO:0140243 name: regulation of translation at synapse namespace: biological_process def: "Any process that regulates translation occurring at the synapse." [PMID:20427644] is_a: GO:0006417 ! regulation of translation intersection_of: GO:0065007 ! biological regulation intersection_of: BFO:0000066 GO:0045202 ! occurs in synapse intersection_of: RO:0002211 GO:0006412 ! regulates (processual) translation relationship: BFO:0000066 GO:0045202 ! occurs in synapse relationship: RO:0002160 NCBITaxon:33208 ! only in taxon Metazoa relationship: RO:0002162 NCBITaxon:33208 {all_only="true"} ! in taxon Metazoa creation_date: 2018-07-15T09:38:26Z [Term] id: GO:0140244 name: regulation of translation at presynapse namespace: biological_process def: "Any process that regulates translation occurring at the presynapse." [PMID:20427644] is_a: GO:0140243 ! regulation of translation at synapse intersection_of: GO:0065007 ! biological regulation intersection_of: BFO:0000066 GO:0098793 ! occurs in presynapse intersection_of: RO:0002211 GO:0006412 ! regulates (processual) translation relationship: BFO:0000066 GO:0098793 ! occurs in presynapse creation_date: 2018-07-15T09:38:33Z [Term] id: GO:0140245 name: regulation of translation at postsynapse namespace: biological_process def: "Any process that regulates translation occurring at the postsynapse." [PMID:20427644] is_a: GO:0140243 ! regulation of translation at synapse intersection_of: GO:0065007 ! biological regulation intersection_of: BFO:0000066 GO:0098794 ! occurs in postsynapse intersection_of: RO:0002211 GO:0006412 ! regulates (processual) translation relationship: BFO:0000066 GO:0098794 ! occurs in postsynapse creation_date: 2018-07-15T09:38:54Z [Term] id: GO:0140246 name: protein catabolic process at synapse namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of a protein at a synapse." [PMID:17062563] is_a: GO:0009057 ! macromolecule catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: BFO:0000066 GO:0045202 ! occurs in synapse intersection_of: RO:0004009 CHEBI:36080 ! has primary input protein relationship: BFO:0000066 GO:0045202 ! occurs in synapse relationship: RO:0002160 NCBITaxon:33208 ! only in taxon Metazoa relationship: RO:0002162 NCBITaxon:33208 {all_only="true"} ! in taxon Metazoa relationship: RO:0004009 CHEBI:36080 ! has primary input protein creation_date: 2018-07-15T10:12:51Z [Term] id: GO:0140247 name: protein catabolic process at presynapse namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of a protein at a presynapse." [PMID:27764673] is_a: GO:0140246 ! protein catabolic process at synapse intersection_of: GO:0009056 ! catabolic process intersection_of: BFO:0000066 GO:0098793 ! occurs in presynapse intersection_of: RO:0004009 CHEBI:36080 ! has primary input protein relationship: BFO:0000066 GO:0098793 ! occurs in presynapse creation_date: 2018-07-15T10:23:49Z [Term] id: GO:0140249 name: protein catabolic process at postsynapse namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of a protein at a postsynapse." [PMID:17062563] is_a: GO:0140246 ! protein catabolic process at synapse intersection_of: GO:0009056 ! catabolic process intersection_of: BFO:0000066 GO:0098794 ! occurs in postsynapse intersection_of: RO:0004009 CHEBI:36080 ! has primary input protein relationship: BFO:0000066 GO:0098794 ! occurs in postsynapse creation_date: 2018-07-15T10:25:04Z [Term] id: GO:0140250 name: regulation protein catabolic process at synapse namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the synapse." [PMID:23083742] is_a: GO:0009894 ! regulation of catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: BFO:0000066 GO:0045202 ! occurs in synapse intersection_of: RO:0002211 GO:0009056 ! regulates (processual) catabolic process intersection_of: RO:0004009 CHEBI:36080 ! has primary input protein relationship: BFO:0000066 GO:0045202 ! occurs in synapse relationship: RO:0002160 NCBITaxon:33208 ! only in taxon Metazoa relationship: RO:0002162 NCBITaxon:33208 {all_only="true"} ! in taxon Metazoa relationship: RO:0004009 CHEBI:36080 ! has primary input protein creation_date: 2018-07-15T10:34:56Z [Term] id: GO:0140251 name: regulation protein catabolic process at presynapse namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the presynapse." [PMID:27764673] is_a: GO:0140250 ! regulation protein catabolic process at synapse intersection_of: GO:0065007 ! biological regulation intersection_of: BFO:0000066 GO:0098793 ! occurs in presynapse intersection_of: RO:0002211 GO:0009056 ! regulates (processual) catabolic process intersection_of: RO:0004009 CHEBI:36080 ! has primary input protein relationship: BFO:0000066 GO:0098793 ! occurs in presynapse creation_date: 2018-07-15T10:35:39Z [Term] id: GO:0140252 name: regulation protein catabolic process at postsynapse namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the postsynapse." [PMID:17062563] is_a: GO:0140250 ! regulation protein catabolic process at synapse intersection_of: GO:0065007 ! biological regulation intersection_of: BFO:0000066 GO:0098794 ! occurs in postsynapse intersection_of: RO:0002211 GO:0009056 ! regulates (processual) catabolic process intersection_of: RO:0004009 CHEBI:36080 ! has primary input protein relationship: BFO:0000066 GO:0098794 ! occurs in postsynapse creation_date: 2018-07-15T10:35:56Z [Term] id: GO:0140253 name: cell-cell fusion namespace: biological_process def: "A cellular process in which two or more cells combine together, their plasma membrane fusing, producing a single cell. In some cases, nuclei fuse, producing a polyploid cell, while in other cases, nuclei remain separate, producing a syncytium." [Wikipedia:Cell_fusion] synonym: "cell cell fusion" EXACT [] is_a: GO:0009987 ! cellular process relationship: BFO:0000051 GO:0045026 ! has part plasma membrane fusion creation_date: 2018-08-13T18:38:18Z [Term] id: GO:0140318 name: protein transporter activity namespace: molecular_function def: "Directly binding to a specific protein and delivering it to a specific cellular location." [PMID:18706423] xref: Reactome:R-HSA-9662747 "iRHOM2 transports ADAM17 from ER to the Golgi-network" xref: Reactome:R-HSA-9662818 "iRHOM2 transports ADAM17:Zn2+ from Golgi to the plasma membrane" is_a: GO:0005215 ! transporter activity intersection_of: GO:0005215 ! transporter activity intersection_of: RO:0004009 PR:000000001 ! has primary input protein relationship: RO:0004009 PR:000000001 ! has primary input protein creation_date: 2019-04-01T10:41:38Z [Term] id: GO:0140352 name: export from cell namespace: biological_process def: "The directed movement of some substance from a cell, into the extracellular region. This may occur via transport across the plasma membrane or via exocytosis." [GOC:pg] is_a: GO:0006810 ! transport is_a: GO:0009987 ! cellular process intersection_of: GO:0006810 ! transport intersection_of: RO:0002338 GO:0005622 ! has target start location intracellular anatomical structure intersection_of: RO:0002339 GO:0005576 ! has target end location extracellular region relationship: RO:0002338 GO:0005622 ! has target start location intracellular anatomical structure relationship: RO:0002339 GO:0005576 ! has target end location extracellular region creation_date: 2019-05-22T11:20:45Z [Term] id: GO:0140353 name: lipid export from cell namespace: biological_process def: "The directed movement of a lipid from a cell, into the extracellular region." [GOC:pg] is_a: GO:0006869 ! lipid transport is_a: GO:0140352 ! export from cell intersection_of: GO:0006810 ! transport intersection_of: RO:0002338 GO:0005622 ! has target start location intracellular anatomical structure intersection_of: RO:0002339 GO:0005576 ! has target end location extracellular region intersection_of: RO:0004009 CHEBI:18059 ! has primary input lipid creation_date: 2019-05-22T11:33:07Z [Term] id: GO:0140354 name: lipid import into cell namespace: biological_process def: "The directed movement of a lipid from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis." [GOC:pg] is_a: GO:0006869 ! lipid transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002338 GO:0005576 ! has target start location extracellular region intersection_of: RO:0002339 GO:0005622 ! has target end location intracellular anatomical structure intersection_of: RO:0004009 CHEBI:18059 ! has primary input lipid relationship: RO:0002338 GO:0005576 ! has target start location extracellular region relationship: RO:0002339 GO:0005622 ! has target end location intracellular anatomical structure creation_date: 2019-05-22T11:38:15Z [Term] id: GO:0140513 name: nuclear protein-containing complex namespace: cellular_component def: "A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together in the nucleus." [GOC:pg] synonym: "nuclear complex" EXACT [] is_a: GO:0032991 ! protein-containing complex intersection_of: GO:0032991 ! protein-containing complex intersection_of: BFO:0000050 GO:0005634 ! part of nucleus relationship: BFO:0000050 GO:0005634 ! part of nucleus creation_date: 2020-09-09T05:12:38Z [Term] id: GO:0140572 name: vacuole fission namespace: biological_process def: "The division of a vacuole within a cell to form two or more separate vacuoles." [PMID:19643199] is_a: GO:0048285 ! organelle fission intersection_of: GO:0048285 ! organelle fission intersection_of: GOREL:0002004 GO:0005773 ! results in fission of vacuole relationship: GOREL:0002004 GO:0005773 ! results in fission of vacuole creation_date: 2021-01-04T10:17:58Z [Term] id: GO:0140640 name: catalytic activity, acting on a nucleic acid namespace: molecular_function def: "Catalytic activity that acts to modify a nucleic acid." [GOC:pg] is_a: GO:0003824 ! catalytic activity intersection_of: GO:0003824 ! catalytic activity intersection_of: RO:0004009 CHEBI:33696 ! has primary input nucleic acid relationship: RO:0004009 CHEBI:33696 ! has primary input nucleic acid creation_date: 2021-05-11T06:31:07Z [Term] id: GO:0140694 name: non-membrane-bounded organelle assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form a non-membrane-bounded organelle." [PMID:28225081] synonym: "non-membrane-bounded organelle formation" EXACT [] synonym: "non-membrane-enclosed organelle assembly" EXACT [] synonym: "non-membrane-enclosed organelle formation" EXACT [] is_a: GO:0070925 ! organelle assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0043228 ! results in assembly of non-membrane-bounded organelle relationship: RO:0002588 GO:0043228 ! results in assembly of non-membrane-bounded organelle creation_date: 2021-08-09T15:30:06Z [Term] id: GO:0140734 name: ammonium excretion namespace: biological_process def: "The elimination of ammonium ions from an excretory cell." [PMID:25740900] is_a: GO:0007588 ! excretion intersection_of: GO:0007588 ! excretion intersection_of: RO:0004009 CHEBI:28938 ! has primary input ammonium relationship: RO:0004009 CHEBI:28938 ! has primary input ammonium creation_date: 2021-11-24T17:55:51Z [Term] id: GO:0140961 name: cellular detoxification of metal ion namespace: biological_process def: "Any process carried out at the cellular level that reduces or removes the toxicity of a metal ion." [PMID:26729300, PMID:33046888, PMID:34442707] synonym: "cellular detoxification of metal cation" EXACT [] is_a: GO:0061687 ! detoxification of inorganic compound is_a: GO:1990748 ! cellular detoxification intersection_of: GO:1990748 ! cellular detoxification intersection_of: RO:0004009 CHEBI:25213 ! has primary input metal cation relationship: RO:0004009 CHEBI:25213 ! has primary input metal cation creation_date: 2022-12-07T15:35:18Z [Term] id: GO:0150052 name: regulation of postsynapse assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of postsynapse assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynapse." [GOC:aruk, GOC:bc, PMID:16394100, PMID:16672654, PMID:28185854] is_a: GO:0051963 ! regulation of synapse assembly is_a: GO:0099175 ! regulation of postsynapse organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0099068 ! regulates (processual) postsynapse assembly relationship: RO:0002211 GO:0099068 ! regulates (processual) postsynapse assembly creation_date: 2018-05-08T16:38:55Z [Term] id: GO:0150063 name: visual system development namespace: biological_process def: "The process whose specific outcome is the progression of the visual system over time, from its formation to the mature structure, including the eye, parts of the central nervous system (CNS) involved in processing of visual inputs, and connecting nerve pathways." [GOC:aruk, GOC:bc, GOC:krc, PMID:15004427, PMID:20647017, PMID:22632727] is_a: GO:0048880 ! sensory system development creation_date: 2018-07-23T10:31:58Z [Term] id: GO:0150076 name: neuroinflammatory response namespace: biological_process def: "The immediate defensive reaction by neural vertebrate tissue to infection or injury caused by chemical or physical agents." [GOC:aruk, GOC:bc, PMID:10981966, PMID:11099416, PMID:18164423] synonym: "nerve tissue inflammatory response" EXACT [] synonym: "nervous tissue inflammatory response" EXACT [] synonym: "neural tissue inflammatory response" EXACT [] is_a: GO:0006954 ! inflammatory response creation_date: 2018-07-26T12:25:34Z [Term] id: GO:0150077 name: regulation of neuroinflammatory response namespace: biological_process def: "Any process that modulates the frequency, rate or extent of neuroinflammatory response." [GOC:aruk, GOC:bc, PMID:10981966, PMID:11099416, PMID:18164423] is_a: GO:0050727 ! regulation of inflammatory response intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0150076 ! regulates (processual) neuroinflammatory response relationship: RO:0002160 NCBITaxon:7742 ! only in taxon Vertebrata relationship: RO:0002162 NCBITaxon:7742 {all_only="true"} ! in taxon Vertebrata relationship: RO:0002211 GO:0150076 ! regulates (processual) neuroinflammatory response creation_date: 2018-07-26T12:32:18Z [Term] id: GO:0150078 name: positive regulation of neuroinflammatory response namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of neuroinflammatory response." [GOC:aruk, GOC:bc] is_a: GO:0050729 ! positive regulation of inflammatory response is_a: GO:0150077 ! regulation of neuroinflammatory response intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0150076 ! positively regulates neuroinflammatory response relationship: RO:0002213 GO:0150076 ! positively regulates neuroinflammatory response creation_date: 2018-07-26T12:35:50Z [Term] id: GO:0150079 name: negative regulation of neuroinflammatory response namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of neuroinflammatory response." [GOC:aruk, GOC:bc, PMID:11099416, PMID:18164423] is_a: GO:0050728 ! negative regulation of inflammatory response is_a: GO:0150077 ! regulation of neuroinflammatory response intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0150076 ! negatively regulates neuroinflammatory response relationship: RO:0002212 GO:0150076 ! negatively regulates neuroinflammatory response creation_date: 2018-07-26T12:38:08Z [Term] id: GO:0150098 name: glial cell-neuron signaling namespace: biological_process def: "Cell-cell signaling that mediates the transfer of information from a glial cell to a neuron. This signaling has been shown to be mediated by various molecules, depending on which glial cells release them, and in which tissues the signaling occurs, e.g. microglial cell-derived nerve growth factor (NGF) in the retina, or microglial cell-derived superoxide ions in the cerebellum." [GOC:aruk, GOC:bc, PMID:14980203, PMID:16144764, PMID:16547515, PMID:18685038, PMID:27788368, PMID:9459440] synonym: "glia-neuron signaling" EXACT [] synonym: "glia-neuron signalling" EXACT [] synonym: "glia-neurone signaling" EXACT [] synonym: "glia-neurone signalling" EXACT [] synonym: "glial cell- neuron signalling" EXACT [] synonym: "glial cell-neurone signalling" EXACT [] synonym: "glial cell-neurone singaling" EXACT [] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: RO:0002231 CL:0000125 ! has start location glial cell intersection_of: RO:0002232 CL:0000540 ! has end location neuron relationship: RO:0002231 CL:0000125 ! has start location glial cell relationship: RO:0002232 CL:0000540 ! has end location neuron creation_date: 2018-12-17T12:28:09Z [Term] id: GO:0150099 name: neuron-glial cell signaling namespace: biological_process def: "Cell-cell signaling that mediates the transfer of information from a neuron to a glial cell. This signaling has been shown to be mediated by various molecules released by different types of neurons, e.g. glutamate, gamma-amino butyric acid (GABA), noradrenaline, acetylcholine, dopamine and adenosine." [GOC:aruk, GOC:bc, PMID:10195197, PMID:10196584, PMID:10377338, PMID:10493741, PMID:11356870, PMID:11399439, PMID:15252819, PMID:27788368] synonym: "neuron-glia signaling" EXACT [] synonym: "neuron-glia signalling" EXACT [] synonym: "neuron-glial cell signalling" EXACT [] synonym: "neurone-glia signaling" EXACT [] synonym: "neurone-glia signalling" EXACT [] synonym: "neurone-glial cell signaling" EXACT [] synonym: "neurone-glial cell signalling" EXACT [] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: RO:0002231 CL:0000540 ! has start location neuron intersection_of: RO:0002232 CL:0000125 ! has end location glial cell relationship: RO:0002231 CL:0000540 ! has start location neuron relationship: RO:0002232 CL:0000125 ! has end location glial cell creation_date: 2018-12-17T12:30:12Z [Term] id: GO:0150105 name: protein localization to cell-cell junction namespace: biological_process def: "A process in which a protein is transported to, or maintained, in a location within a cell-cell junction." [GOC:aruk, GOC:bc, PMID:26706435] is_a: GO:1902414 ! protein localization to cell junction intersection_of: GO:0008104 ! protein localization intersection_of: RO:0002339 GO:0005911 ! has target end location cell-cell junction relationship: RO:0002339 GO:0005911 ! has target end location cell-cell junction creation_date: 2019-06-11T11:00:18Z [Term] id: GO:0150106 name: regulation of protein localization to cell-cell junction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein localization to cell-cell junction." [GOC:aruk, GOC:bc, PMID:26706435] is_a: GO:0032880 ! regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0150105 ! regulates (processual) protein localization to cell-cell junction relationship: RO:0002211 GO:0150105 ! regulates (processual) protein localization to cell-cell junction creation_date: 2019-06-11T11:17:15Z [Term] id: GO:0150107 name: positive regulation of protein localization to cell-cell junction namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein localization to cell-cell junction." [GOC:aruk, GOC:bc, PMID:26706435] is_a: GO:0150106 ! regulation of protein localization to cell-cell junction is_a: GO:1903829 ! positive regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0150105 ! positively regulates protein localization to cell-cell junction relationship: RO:0002213 GO:0150105 ! positively regulates protein localization to cell-cell junction creation_date: 2019-06-11T11:23:58Z [Term] id: GO:0150111 name: regulation of transepithelial transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of transepithelial transport." [GOC:aruk, PMID:27593915] is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0070633 ! regulates (processual) transepithelial transport relationship: RO:0002211 GO:0070633 ! regulates (processual) transepithelial transport creation_date: 2019-09-15T07:16:49Z [Term] id: GO:0150119 name: negative regulation of protein localization to cell-cell junction namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell-cell junction." [GOC:aruk, GOC:bc] synonym: "negative regulation of protein localisation to cell-cell junction" EXACT [] is_a: GO:0150106 ! regulation of protein localization to cell-cell junction is_a: GO:1903828 ! negative regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0150105 ! negatively regulates protein localization to cell-cell junction relationship: RO:0002212 GO:0150105 ! negatively regulates protein localization to cell-cell junction creation_date: 2019-11-21T13:53:34Z [Term] id: GO:0150146 name: cell junction disassembly namespace: biological_process def: "The disaggregation of a cell junction into its constituent components." [GOC:aruk, PMID:25490267] is_a: GO:0022411 ! cellular component disassembly is_a: GO:0034330 ! cell junction organization intersection_of: GO:0022411 ! cellular component disassembly intersection_of: RO:0002590 GO:0030054 ! results in disassembly of cell junction relationship: RO:0002590 GO:0030054 ! results in disassembly of cell junction creation_date: 2019-12-08T11:12:13Z [Term] id: GO:0150147 name: cell-cell junction disassembly namespace: biological_process def: "The disaggregation of a cell-cell junction into its constituent components." [GOC:aruk, PMID:25490267] is_a: GO:0045216 ! cell-cell junction organization is_a: GO:0150146 ! cell junction disassembly intersection_of: GO:0022411 ! cellular component disassembly intersection_of: RO:0002590 GO:0005911 ! results in disassembly of cell-cell junction relationship: RO:0002590 GO:0005911 ! results in disassembly of cell-cell junction creation_date: 2019-12-08T11:16:14Z [Term] id: GO:0160038 name: somatic sensory system development namespace: biological_process def: "The process whose specific outcome is the progression of a somatic sensory system over time from its formation to the mature structure. Somatic sensory system is the sensory system for the sense of touch and pain." [PMID:25832476, PMID:31399790] synonym: "somatosensory system development" EXACT [] is_a: GO:0048880 ! sensory system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003942 ! results in development of somatosensory system relationship: RO:0002296 UBERON:0003942 ! results in development of somatosensory system creation_date: 2022-07-07T16:49:26Z [Term] id: GO:0160043 name: catecholamine secretion, neurotransmission namespace: biological_process def: "The regulated release of catecholamine by a cell in which the catecholamine acts as a neurotransmitter." [PMID:10191060] is_a: GO:0007269 ! neurotransmitter secretion is_a: GO:0050432 ! catecholamine secretion intersection_of: GO:0007269 ! neurotransmitter secretion intersection_of: RO:0004009 CHEBI:33567 ! has primary input catecholamine creation_date: 2022-08-17T00:36:44Z [Term] id: GO:0160093 name: chordate pharynx development namespace: biological_process def: "The process whose specific outcome is the progression of cordate pharynx over time, from its formation to the mature structure." [PMID:23020903] is_a: GO:0060465 ! pharynx development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001042 ! results in development of chordate pharynx relationship: RO:0002296 UBERON:0001042 ! results in development of chordate pharynx creation_date: 2023-08-29T21:05:28Z [Term] id: GO:1900015 name: regulation of cytokine production involved in inflammatory response namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cytokine production involved in inflammatory response." [GOC:TermGenie] is_a: GO:0001817 ! regulation of cytokine production intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002534 ! regulates (processual) cytokine production involved in inflammatory response relationship: RO:0002211 GO:0002534 ! regulates (processual) cytokine production involved in inflammatory response creation_date: 2012-01-11T09:34:27Z [Term] id: GO:1900016 name: negative regulation of cytokine production involved in inflammatory response namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cytokine production involved in inflammatory response." [GOC:TermGenie] is_a: GO:0001818 ! negative regulation of cytokine production is_a: GO:1900015 ! regulation of cytokine production involved in inflammatory response intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002534 ! negatively regulates cytokine production involved in inflammatory response relationship: RO:0002212 GO:0002534 ! negatively regulates cytokine production involved in inflammatory response creation_date: 2012-01-11T09:34:31Z [Term] id: GO:1900017 name: positive regulation of cytokine production involved in inflammatory response namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cytokine production involved in inflammatory response." [GOC:TermGenie] is_a: GO:0001819 ! positive regulation of cytokine production is_a: GO:1900015 ! regulation of cytokine production involved in inflammatory response intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002534 ! positively regulates cytokine production involved in inflammatory response relationship: RO:0002213 GO:0002534 ! positively regulates cytokine production involved in inflammatory response creation_date: 2012-01-11T09:34:35Z [Term] id: GO:1900073 name: regulation of neuromuscular synaptic transmission namespace: biological_process def: "Any process that modulates the frequency, rate or extent of neuromuscular synaptic transmission." [GOC:kmv, GOC:TermGenie] is_a: GO:0050804 ! modulation of chemical synaptic transmission intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007274 ! regulates (processual) neuromuscular synaptic transmission relationship: RO:0002211 GO:0007274 ! regulates (processual) neuromuscular synaptic transmission creation_date: 2012-01-26T10:14:10Z [Term] id: GO:1900074 name: negative regulation of neuromuscular synaptic transmission namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular synaptic transmission." [GOC:kmv, GOC:TermGenie] is_a: GO:0050805 ! negative regulation of synaptic transmission is_a: GO:1900073 ! regulation of neuromuscular synaptic transmission intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007274 ! negatively regulates neuromuscular synaptic transmission relationship: RO:0002212 GO:0007274 ! negatively regulates neuromuscular synaptic transmission creation_date: 2012-01-26T10:14:18Z [Term] id: GO:1900075 name: positive regulation of neuromuscular synaptic transmission namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of neuromuscular synaptic transmission." [GOC:kmv, GOC:TermGenie] is_a: GO:0050806 ! positive regulation of synaptic transmission is_a: GO:1900073 ! regulation of neuromuscular synaptic transmission intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007274 ! positively regulates neuromuscular synaptic transmission relationship: RO:0002213 GO:0007274 ! positively regulates neuromuscular synaptic transmission creation_date: 2012-01-26T10:14:22Z [Term] id: GO:1900115 name: extracellular regulation of signal transduction namespace: biological_process def: "Any regulation of signal transduction that takes place in the extracellular region." [GOC:signaling, GOC:TermGenie] synonym: "regulation of signaling pathway in extracellular region" EXACT [GOC:TermGenie] synonym: "regulation of signalling pathway in extracellular region" EXACT [GOC:TermGenie] is_a: GO:0009966 ! regulation of signal transduction intersection_of: GO:0009966 ! regulation of signal transduction intersection_of: BFO:0000066 GO:0005576 ! occurs in extracellular region relationship: BFO:0000066 GO:0005576 ! occurs in extracellular region creation_date: 2012-02-22T10:21:48Z [Term] id: GO:1900116 name: extracellular negative regulation of signal transduction namespace: biological_process def: "Any negative regulation of signal transduction that takes place in extracellular region." [GOC:signaling, GOC:TermGenie] synonym: "down regulation of signal transduction in extracellular region" EXACT [GOC:TermGenie] synonym: "down-regulation of signal transduction in extracellular region" EXACT [GOC:TermGenie] synonym: "downregulation of signal transduction in extracellular region" EXACT [GOC:TermGenie] synonym: "negative regulation of signaling pathway in extracellular region" EXACT [GOC:TermGenie] synonym: "negative regulation of signalling pathway in extracellular region" EXACT [GOC:TermGenie] is_a: GO:0009968 ! negative regulation of signal transduction is_a: GO:1900115 ! extracellular regulation of signal transduction intersection_of: GO:0009968 ! negative regulation of signal transduction intersection_of: BFO:0000066 GO:0005576 ! occurs in extracellular region creation_date: 2012-02-22T10:27:56Z [Term] id: GO:1900117 name: regulation of execution phase of apoptosis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of execution phase of apoptosis." [GOC:mtg_apoptosis, GOC:TermGenie] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0097194 ! regulates (processual) execution phase of apoptosis relationship: RO:0002211 GO:0097194 ! regulates (processual) execution phase of apoptosis creation_date: 2012-02-22T11:26:20Z [Term] id: GO:1900118 name: negative regulation of execution phase of apoptosis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of execution phase of apoptosis." [GOC:mtg_apoptosis, GOC:TermGenie] synonym: "down regulation of execution phase of apoptosis" EXACT [GOC:TermGenie] synonym: "down-regulation of execution phase of apoptosis" EXACT [GOC:TermGenie] synonym: "downregulation of execution phase of apoptosis" EXACT [GOC:TermGenie] is_a: GO:0043066 ! negative regulation of apoptotic process is_a: GO:1900117 ! regulation of execution phase of apoptosis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0097194 ! negatively regulates execution phase of apoptosis relationship: RO:0002212 GO:0097194 ! negatively regulates execution phase of apoptosis creation_date: 2012-02-22T11:26:24Z [Term] id: GO:1900119 name: positive regulation of execution phase of apoptosis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of execution phase of apoptosis." [GOC:mtg_apoptosis, GOC:TermGenie] synonym: "up regulation of execution phase of apoptosis" EXACT [GOC:TermGenie] synonym: "up-regulation of execution phase of apoptosis" EXACT [GOC:TermGenie] synonym: "upregulation of execution phase of apoptosis" EXACT [GOC:TermGenie] is_a: GO:0043065 ! positive regulation of apoptotic process is_a: GO:1900117 ! regulation of execution phase of apoptosis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0097194 ! positively regulates execution phase of apoptosis relationship: RO:0002213 GO:0097194 ! positively regulates execution phase of apoptosis creation_date: 2012-02-22T11:26:27Z [Term] id: GO:1900125 name: regulation of hyaluronan biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of hyaluronan biosynthetic process." [GOC:TermGenie, GOC:yaf] synonym: "regulation of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "regulation of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "regulation of hyaluronan synthesis" EXACT [GOC:TermGenie] is_a: GO:0032885 ! regulation of polysaccharide biosynthetic process is_a: GO:0051171 ! regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030213 ! regulates (processual) hyaluronan biosynthetic process relationship: RO:0002211 GO:0030213 ! regulates (processual) hyaluronan biosynthetic process creation_date: 2012-02-23T01:09:21Z [Term] id: GO:1900126 name: negative regulation of hyaluronan biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of hyaluronan biosynthetic process." [GOC:TermGenie, GOC:yaf] synonym: "down regulation of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "down regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "down regulation of hyaluronan biosynthetic process" EXACT [GOC:TermGenie] synonym: "down regulation of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "down regulation of hyaluronan synthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of hyaluronan biosynthetic process" EXACT [GOC:TermGenie] synonym: "down-regulation of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "down-regulation of hyaluronan synthesis" EXACT [GOC:TermGenie] synonym: "downregulation of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "downregulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "downregulation of hyaluronan biosynthetic process" EXACT [GOC:TermGenie] synonym: "downregulation of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "downregulation of hyaluronan synthesis" EXACT [GOC:TermGenie] synonym: "inhibition of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "inhibition of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "inhibition of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "inhibition of hyaluronan synthesis" EXACT [GOC:TermGenie] synonym: "negative regulation of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "negative regulation of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "negative regulation of hyaluronan synthesis" EXACT [GOC:TermGenie] is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process is_a: GO:0045912 ! negative regulation of carbohydrate metabolic process is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process is_a: GO:1900125 ! regulation of hyaluronan biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030213 ! negatively regulates hyaluronan biosynthetic process relationship: RO:0002212 GO:0030213 ! negatively regulates hyaluronan biosynthetic process creation_date: 2012-02-23T01:09:29Z [Term] id: GO:1900127 name: positive regulation of hyaluronan biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of hyaluronan biosynthetic process." [GOC:TermGenie, GOC:yaf] synonym: "activation of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "activation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "activation of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "activation of hyaluronan synthesis" EXACT [GOC:TermGenie] synonym: "positive regulation of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "positive regulation of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "positive regulation of hyaluronan synthesis" EXACT [GOC:TermGenie] synonym: "up regulation of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "up regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "up regulation of hyaluronan biosynthetic process" EXACT [GOC:TermGenie] synonym: "up regulation of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "up regulation of hyaluronan synthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of hyaluronan biosynthetic process" EXACT [GOC:TermGenie] synonym: "up-regulation of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "up-regulation of hyaluronan synthesis" EXACT [GOC:TermGenie] synonym: "upregulation of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "upregulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "upregulation of hyaluronan biosynthetic process" EXACT [GOC:TermGenie] synonym: "upregulation of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "upregulation of hyaluronan synthesis" EXACT [GOC:TermGenie] is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process is_a: GO:0045913 ! positive regulation of carbohydrate metabolic process is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process is_a: GO:1900125 ! regulation of hyaluronan biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030213 ! positively regulates hyaluronan biosynthetic process relationship: RO:0002213 GO:0030213 ! positively regulates hyaluronan biosynthetic process creation_date: 2012-02-23T01:09:33Z [Term] id: GO:1900150 name: regulation of defense response to fungus namespace: biological_process def: "Any process that modulates the frequency, rate or extent of defense response to fungus." [GOC:dhl, GOC:TermGenie, PMID:22242006] synonym: "regulation of defence response to fungi" EXACT [GOC:TermGenie] synonym: "regulation of defence response to fungus" EXACT [GOC:TermGenie] synonym: "regulation of defense response to fungi" EXACT [GOC:TermGenie] is_a: GO:0002831 ! regulation of response to biotic stimulus is_a: GO:0031347 ! regulation of defense response is_a: GO:0032101 ! regulation of response to external stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0050832 ! regulates (processual) defense response to fungus relationship: RO:0002211 GO:0050832 ! regulates (processual) defense response to fungus creation_date: 2012-03-06T10:00:16Z [Term] id: GO:1900180 name: regulation of protein localization to nucleus namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein localization to nucleus." [GOC:TermGenie] synonym: "regulation of protein localisation to nucleus" EXACT [GOC:TermGenie] synonym: "regulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] synonym: "regulation of protein localization in nucleus" EXACT [GOC:TermGenie] is_a: GO:0032880 ! regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0034504 ! regulates (processual) protein localization to nucleus relationship: RO:0002211 GO:0034504 ! regulates (processual) protein localization to nucleus creation_date: 2012-03-12T01:23:44Z [Term] id: GO:1900181 name: negative regulation of protein localization to nucleus namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleus." [GOC:TermGenie] synonym: "down regulation of protein localisation to nucleus" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization in nucleus" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization to nucleus" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation to nucleus" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization in nucleus" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to nucleus" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation to nucleus" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization in nucleus" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to nucleus" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localisation to nucleus" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localization in nucleus" EXACT [GOC:TermGenie] is_a: GO:1900180 ! regulation of protein localization to nucleus is_a: GO:1903828 ! negative regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0034504 ! negatively regulates protein localization to nucleus relationship: RO:0002212 GO:0034504 ! negatively regulates protein localization to nucleus creation_date: 2012-03-12T01:23:48Z [Term] id: GO:1900182 name: positive regulation of protein localization to nucleus namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein localization to nucleus." [GOC:TermGenie] synonym: "activation of protein localization in nucleus" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localisation to nucleus" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localization in nucleus" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation to nucleus" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization in nucleus" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization to nucleus" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation to nucleus" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization in nucleus" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to nucleus" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation to nucleus" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization in nucleus" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to nucleus" EXACT [GOC:TermGenie] is_a: GO:1900180 ! regulation of protein localization to nucleus is_a: GO:1903829 ! positive regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0034504 ! positively regulates protein localization to nucleus relationship: RO:0002213 GO:0034504 ! positively regulates protein localization to nucleus creation_date: 2012-03-12T01:23:52Z [Term] id: GO:1900193 name: regulation of oocyte maturation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of oocyte maturation." [GOC:kmv, GOC:TermGenie] is_a: GO:1903429 ! regulation of cell maturation is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001556 ! regulates (processual) oocyte maturation relationship: RO:0002211 GO:0001556 ! regulates (processual) oocyte maturation creation_date: 2012-03-19T09:41:18Z [Term] id: GO:1900194 name: negative regulation of oocyte maturation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of oocyte maturation." [GOC:kmv, GOC:TermGenie] synonym: "down regulation of oocyte maturation" EXACT [GOC:TermGenie] synonym: "down-regulation of oocyte maturation" EXACT [GOC:TermGenie] synonym: "downregulation of oocyte maturation" EXACT [GOC:TermGenie] is_a: GO:1900193 ! regulation of oocyte maturation is_a: GO:1903430 ! negative regulation of cell maturation is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001556 ! negatively regulates oocyte maturation relationship: RO:0002212 GO:0001556 ! negatively regulates oocyte maturation creation_date: 2012-03-19T09:41:27Z [Term] id: GO:1900195 name: positive regulation of oocyte maturation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of oocyte maturation." [GOC:kmv, GOC:TermGenie] synonym: "up regulation of oocyte maturation" EXACT [GOC:TermGenie] synonym: "up-regulation of oocyte maturation" EXACT [GOC:TermGenie] synonym: "upregulation of oocyte maturation" EXACT [GOC:TermGenie] is_a: GO:1900193 ! regulation of oocyte maturation is_a: GO:1903431 ! positive regulation of cell maturation is_a: GO:2000243 ! positive regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001556 ! positively regulates oocyte maturation relationship: RO:0002213 GO:0001556 ! positively regulates oocyte maturation creation_date: 2012-03-19T09:41:35Z [Term] id: GO:1900200 name: mesenchymal cell apoptotic process involved in metanephros development namespace: biological_process def: "Any mesenchymal cell apoptotic process that is involved in metanephros development." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] is_a: GO:0097152 ! mesenchymal cell apoptotic process is_a: GO:1902742 ! apoptotic process involved in development intersection_of: GO:0097152 ! mesenchymal cell apoptotic process intersection_of: BFO:0000050 GO:0001656 ! part of metanephros development relationship: BFO:0000050 GO:0001656 ! part of metanephros development creation_date: 2012-03-21T11:58:05Z [Term] id: GO:1900204 name: apoptotic process involved in metanephric collecting duct development namespace: biological_process def: "Any apoptotic process that is involved in metanephric collecting duct development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] is_a: GO:1902742 ! apoptotic process involved in development intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000050 GO:0072205 ! part of metanephric collecting duct development relationship: BFO:0000050 GO:0072205 ! part of metanephric collecting duct development creation_date: 2012-03-21T01:21:32Z [Term] id: GO:1900205 name: apoptotic process involved in metanephric nephron tubule development namespace: biological_process def: "Any apoptotic process that is involved in metanephric nephron tubule development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] is_a: GO:1902742 ! apoptotic process involved in development intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000050 GO:0072234 ! part of metanephric nephron tubule development relationship: BFO:0000050 GO:0072234 ! part of metanephric nephron tubule development creation_date: 2012-03-21T01:21:45Z [Term] id: GO:1900206 name: regulation of pronephric nephron tubule development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of pronephric nephron tubule development." [GOC:TermGenie] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0039020 ! regulates (processual) pronephric nephron tubule development relationship: RO:0002211 GO:0039020 ! regulates (processual) pronephric nephron tubule development creation_date: 2012-03-22T09:23:13Z [Term] id: GO:1900207 name: negative regulation of pronephric nephron tubule development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of pronephric nephron tubule development." [GOC:bf, GOC:TermGenie, PMID:9758706] synonym: "down regulation of pronephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "down-regulation of pronephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "downregulation of pronephric nephron tubule development" EXACT [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:1900206 ! regulation of pronephric nephron tubule development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0039020 ! negatively regulates pronephric nephron tubule development relationship: RO:0002212 GO:0039020 ! negatively regulates pronephric nephron tubule development creation_date: 2012-03-22T09:23:23Z [Term] id: GO:1900211 name: regulation of mesenchymal cell apoptotic process involved in metanephros development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] is_a: GO:1904748 ! regulation of apoptotic process involved in development is_a: GO:2001053 ! regulation of mesenchymal cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1900200 ! regulates (processual) mesenchymal cell apoptotic process involved in metanephros development relationship: RO:0002211 GO:1900200 ! regulates (processual) mesenchymal cell apoptotic process involved in metanephros development creation_date: 2012-03-22T10:52:50Z [Term] id: GO:1900212 name: negative regulation of mesenchymal cell apoptotic process involved in metanephros development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "down regulation of mesenchymal cell apoptosis involved in metanephros development" EXACT [GOC:TermGenie] synonym: "down-regulation of mesenchymal cell apoptosis involved in metanephros development" EXACT [GOC:TermGenie] synonym: "downregulation of mesenchymal cell apoptosis involved in metanephros development" EXACT [GOC:TermGenie] is_a: GO:1900211 ! regulation of mesenchymal cell apoptotic process involved in metanephros development is_a: GO:1904746 ! negative regulation of apoptotic process involved in development is_a: GO:2001054 ! negative regulation of mesenchymal cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1900200 ! negatively regulates mesenchymal cell apoptotic process involved in metanephros development relationship: RO:0002212 GO:1900200 ! negatively regulates mesenchymal cell apoptotic process involved in metanephros development creation_date: 2012-03-22T10:53:00Z [Term] id: GO:1900213 name: positive regulation of mesenchymal cell apoptotic process involved in metanephros development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "up regulation of mesenchymal cell apoptosis involved in metanephros development" EXACT [GOC:TermGenie] synonym: "up-regulation of mesenchymal cell apoptosis involved in metanephros development" EXACT [GOC:TermGenie] synonym: "upregulation of mesenchymal cell apoptosis involved in metanephros development" EXACT [GOC:TermGenie] is_a: GO:1900211 ! regulation of mesenchymal cell apoptotic process involved in metanephros development is_a: GO:1904747 ! positive regulation of apoptotic process involved in development is_a: GO:2001055 ! positive regulation of mesenchymal cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1900200 ! positively regulates mesenchymal cell apoptotic process involved in metanephros development relationship: RO:0002213 GO:1900200 ! positively regulates mesenchymal cell apoptotic process involved in metanephros development creation_date: 2012-03-22T10:53:09Z [Term] id: GO:1900214 name: regulation of apoptotic process involved in metanephric collecting duct development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "regulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "regulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "regulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "regulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] is_a: GO:1904748 ! regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1900204 ! regulates (processual) apoptotic process involved in metanephric collecting duct development relationship: RO:0002211 GO:1900204 ! regulates (processual) apoptotic process involved in metanephric collecting duct development creation_date: 2012-03-22T10:53:21Z [Term] id: GO:1900215 name: negative regulation of apoptotic process involved in metanephric collecting duct development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "down regulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic process involved in metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "down regulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic process involved in metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "down-regulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic process involved in metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "downregulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "inhibition of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "inhibition of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "inhibition of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "inhibition of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "negative regulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "negative regulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "negative regulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "negative regulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] is_a: GO:1900214 ! regulation of apoptotic process involved in metanephric collecting duct development is_a: GO:1904746 ! negative regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1900204 ! negatively regulates apoptotic process involved in metanephric collecting duct development relationship: RO:0002212 GO:1900204 ! negatively regulates apoptotic process involved in metanephric collecting duct development creation_date: 2012-03-22T10:53:31Z [Term] id: GO:1900216 name: positive regulation of apoptotic process involved in metanephric collecting duct development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "activation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "activation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "activation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "activation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "positive regulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "positive regulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "positive regulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "positive regulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic process involved in metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "up regulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic process involved in metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "up-regulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic process involved in metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "upregulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] is_a: GO:1900214 ! regulation of apoptotic process involved in metanephric collecting duct development is_a: GO:1904747 ! positive regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1900204 ! positively regulates apoptotic process involved in metanephric collecting duct development relationship: RO:0002213 GO:1900204 ! positively regulates apoptotic process involved in metanephric collecting duct development creation_date: 2012-03-22T10:53:39Z [Term] id: GO:1900217 name: regulation of apoptotic process involved in metanephric nephron tubule development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "regulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "regulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "regulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "regulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] is_a: GO:1904748 ! regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1900205 ! regulates (processual) apoptotic process involved in metanephric nephron tubule development relationship: RO:0002211 GO:1900205 ! regulates (processual) apoptotic process involved in metanephric nephron tubule development creation_date: 2012-03-22T10:53:51Z [Term] id: GO:1900218 name: negative regulation of apoptotic process involved in metanephric nephron tubule development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "down regulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic process involved in metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "down regulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic process involved in metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "down-regulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic process involved in metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "downregulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "inhibition of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "inhibition of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "inhibition of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "inhibition of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "negative regulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "negative regulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "negative regulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "negative regulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] is_a: GO:1900217 ! regulation of apoptotic process involved in metanephric nephron tubule development is_a: GO:1904746 ! negative regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1900205 ! negatively regulates apoptotic process involved in metanephric nephron tubule development relationship: RO:0002212 GO:1900205 ! negatively regulates apoptotic process involved in metanephric nephron tubule development creation_date: 2012-03-22T10:54:01Z [Term] id: GO:1900219 name: positive regulation of apoptotic process involved in metanephric nephron tubule development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "activation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "activation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "activation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "activation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "positive regulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "positive regulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "positive regulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "positive regulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic process involved in metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "up regulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic process involved in metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "up-regulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic process involved in metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "upregulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] is_a: GO:1900217 ! regulation of apoptotic process involved in metanephric nephron tubule development is_a: GO:1904747 ! positive regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1900205 ! positively regulates apoptotic process involved in metanephric nephron tubule development relationship: RO:0002213 GO:1900205 ! positively regulates apoptotic process involved in metanephric nephron tubule development creation_date: 2012-03-22T10:54:09Z [Term] id: GO:1900366 name: negative regulation of defense response to insect namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of defense response to insect." [GOC:TermGenie, PMID:22474183] synonym: "down regulation of defense response to insect" EXACT [GOC:TermGenie] synonym: "down regulation of physiological defense response to insect" EXACT [GOC:TermGenie] synonym: "down-regulation of defense response to insect" EXACT [GOC:TermGenie] synonym: "down-regulation of physiological defense response to insect" EXACT [GOC:TermGenie] synonym: "downregulation of defense response to insect" EXACT [GOC:TermGenie] synonym: "downregulation of physiological defense response to insect" EXACT [GOC:TermGenie] synonym: "negative regulation of physiological defense response to insect" EXACT [GOC:TermGenie] is_a: GO:0031348 ! negative regulation of defense response is_a: GO:2000068 ! regulation of defense response to insect intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002213 ! negatively regulates defense response to insect relationship: RO:0002212 GO:0002213 ! negatively regulates defense response to insect creation_date: 2012-04-12T04:44:00Z [Term] id: GO:1900367 name: positive regulation of defense response to insect namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of defense response to insect." [GOC:TermGenie, PMID:22474183] synonym: "positive regulation of physiological defense response to insect" EXACT [GOC:TermGenie] synonym: "up regulation of defense response to insect" EXACT [GOC:TermGenie] synonym: "up regulation of physiological defense response to insect" EXACT [GOC:TermGenie] synonym: "up-regulation of defense response to insect" EXACT [GOC:TermGenie] synonym: "up-regulation of physiological defense response to insect" EXACT [GOC:TermGenie] synonym: "upregulation of defense response to insect" EXACT [GOC:TermGenie] synonym: "upregulation of physiological defense response to insect" EXACT [GOC:TermGenie] is_a: GO:0031349 ! positive regulation of defense response is_a: GO:2000068 ! regulation of defense response to insect intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002213 ! positively regulates defense response to insect relationship: RO:0002213 GO:0002213 ! positively regulates defense response to insect creation_date: 2012-04-12T04:44:10Z [Term] id: GO:1900376 name: regulation of secondary metabolite biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of secondary metabolite biosynthetic process." [GOC:di, GOC:TermGenie] synonym: "regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] is_a: GO:0009889 ! regulation of biosynthetic process is_a: GO:0043455 ! regulation of secondary metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0044550 ! regulates (processual) secondary metabolite biosynthetic process relationship: RO:0002211 GO:0044550 ! regulates (processual) secondary metabolite biosynthetic process creation_date: 2012-04-17T01:55:23Z [Term] id: GO:1900377 name: negative regulation of secondary metabolite biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of secondary metabolite biosynthetic process." [GOC:di, GOC:TermGenie] synonym: "down regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] synonym: "down regulation of secondary metabolite biosynthetic process" EXACT [GOC:TermGenie] synonym: "down-regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of secondary metabolite biosynthetic process" EXACT [GOC:TermGenie] synonym: "downregulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] synonym: "downregulation of secondary metabolite biosynthetic process" EXACT [GOC:TermGenie] synonym: "inhibition of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] synonym: "negative regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] is_a: GO:0009890 ! negative regulation of biosynthetic process is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0044550 ! negatively regulates secondary metabolite biosynthetic process relationship: RO:0002212 GO:0044550 ! negatively regulates secondary metabolite biosynthetic process creation_date: 2012-04-17T01:55:32Z [Term] id: GO:1900378 name: positive regulation of secondary metabolite biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of secondary metabolite biosynthetic process." [GOC:di, GOC:TermGenie] synonym: "activation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] synonym: "positive regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] synonym: "up regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] synonym: "up regulation of secondary metabolite biosynthetic process" EXACT [GOC:TermGenie] synonym: "up-regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of secondary metabolite biosynthetic process" EXACT [GOC:TermGenie] synonym: "upregulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] synonym: "upregulation of secondary metabolite biosynthetic process" EXACT [GOC:TermGenie] is_a: GO:0009891 ! positive regulation of biosynthetic process is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0044550 ! positively regulates secondary metabolite biosynthetic process relationship: RO:0002213 GO:0044550 ! positively regulates secondary metabolite biosynthetic process creation_date: 2012-04-17T01:55:41Z [Term] id: GO:1900424 name: regulation of defense response to bacterium namespace: biological_process def: "Any process that modulates the frequency, rate or extent of defense response to bacterium." [GOC:TermGenie, PMID:22346749] synonym: "regulation of defence response to bacteria" EXACT [GOC:TermGenie] synonym: "regulation of defence response to bacterium" EXACT [GOC:TermGenie] synonym: "regulation of defense response to bacteria" EXACT [GOC:TermGenie] is_a: GO:0002831 ! regulation of response to biotic stimulus is_a: GO:0031347 ! regulation of defense response is_a: GO:0032101 ! regulation of response to external stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0042742 ! regulates (processual) defense response to bacterium relationship: RO:0002211 GO:0042742 ! regulates (processual) defense response to bacterium creation_date: 2012-04-24T10:12:43Z [Term] id: GO:1900425 name: negative regulation of defense response to bacterium namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of defense response to bacterium." [GOC:TermGenie, PMID:22346749] synonym: "down regulation of defence response to bacteria" EXACT [GOC:TermGenie] synonym: "down regulation of defence response to bacterium" EXACT [GOC:TermGenie] synonym: "down regulation of defense response to bacteria" EXACT [GOC:TermGenie] synonym: "down regulation of defense response to bacterium" EXACT [GOC:TermGenie] synonym: "down-regulation of defence response to bacteria" EXACT [GOC:TermGenie] synonym: "down-regulation of defence response to bacterium" EXACT [GOC:TermGenie] synonym: "down-regulation of defense response to bacteria" EXACT [GOC:TermGenie] synonym: "down-regulation of defense response to bacterium" EXACT [GOC:TermGenie] synonym: "downregulation of defence response to bacteria" EXACT [GOC:TermGenie] synonym: "downregulation of defence response to bacterium" EXACT [GOC:TermGenie] synonym: "downregulation of defense response to bacteria" EXACT [GOC:TermGenie] synonym: "downregulation of defense response to bacterium" EXACT [GOC:TermGenie] synonym: "inhibition of defence response to bacteria" EXACT [GOC:TermGenie] synonym: "inhibition of defence response to bacterium" EXACT [GOC:TermGenie] synonym: "inhibition of defense response to bacteria" EXACT [GOC:TermGenie] synonym: "negative regulation of defence response to bacteria" EXACT [GOC:TermGenie] synonym: "negative regulation of defence response to bacterium" EXACT [GOC:TermGenie] synonym: "negative regulation of defense response to bacteria" EXACT [GOC:TermGenie] is_a: GO:0002832 ! negative regulation of response to biotic stimulus is_a: GO:0031348 ! negative regulation of defense response is_a: GO:0032102 ! negative regulation of response to external stimulus is_a: GO:1900424 ! regulation of defense response to bacterium intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0042742 ! negatively regulates defense response to bacterium relationship: RO:0002212 GO:0042742 ! negatively regulates defense response to bacterium creation_date: 2012-04-24T10:12:54Z [Term] id: GO:1900426 name: positive regulation of defense response to bacterium namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of defense response to bacterium." [GOC:TermGenie, PMID:22346749] synonym: "activation of defence response to bacteria" EXACT [GOC:TermGenie] synonym: "activation of defence response to bacterium" EXACT [GOC:TermGenie] synonym: "activation of defense response to bacteria" EXACT [GOC:TermGenie] synonym: "positive regulation of defence response to bacteria" EXACT [GOC:TermGenie] synonym: "positive regulation of defence response to bacterium" EXACT [GOC:TermGenie] synonym: "positive regulation of defense response to bacteria" EXACT [GOC:TermGenie] synonym: "up regulation of defence response to bacteria" EXACT [GOC:TermGenie] synonym: "up regulation of defence response to bacterium" EXACT [GOC:TermGenie] synonym: "up regulation of defense response to bacteria" EXACT [GOC:TermGenie] synonym: "up regulation of defense response to bacterium" EXACT [GOC:TermGenie] synonym: "up-regulation of defence response to bacteria" EXACT [GOC:TermGenie] synonym: "up-regulation of defence response to bacterium" EXACT [GOC:TermGenie] synonym: "up-regulation of defense response to bacteria" EXACT [GOC:TermGenie] synonym: "up-regulation of defense response to bacterium" EXACT [GOC:TermGenie] synonym: "upregulation of defence response to bacteria" EXACT [GOC:TermGenie] synonym: "upregulation of defence response to bacterium" EXACT [GOC:TermGenie] synonym: "upregulation of defense response to bacteria" EXACT [GOC:TermGenie] synonym: "upregulation of defense response to bacterium" EXACT [GOC:TermGenie] is_a: GO:0002833 ! positive regulation of response to biotic stimulus is_a: GO:0031349 ! positive regulation of defense response is_a: GO:0032103 ! positive regulation of response to external stimulus is_a: GO:1900424 ! regulation of defense response to bacterium intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0042742 ! positively regulates defense response to bacterium relationship: RO:0002213 GO:0042742 ! positively regulates defense response to bacterium creation_date: 2012-04-24T10:13:13Z [Term] id: GO:1900619 name: acetate ester metabolic process namespace: biological_process def: "The chemical reactions and pathways involving an acetate ester, any carboxylic ester where the carboxylic acid component is acetic acid." [GOC:TermGenie] synonym: "acetate ester metabolism" EXACT [GOC:TermGenie] synonym: "acetyl ester metabolic process" EXACT [CHEBI:47622] synonym: "acetyl ester metabolism" EXACT [CHEBI:47622] is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:47622 ! has primary input or output acetate ester relationship: RO:0004007 CHEBI:47622 ! has primary input or output acetate ester creation_date: 2012-05-16T12:29:51Z [Term] id: GO:1900620 name: acetate ester biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of an acetate esteran acetate ester, any carboxylic ester where the carboxylic acid component is acetic acid." [GOC:TermGenie, PMID:15042596] synonym: "acetate ester anabolism" EXACT [GOC:TermGenie] synonym: "acetate ester biosynthesis" EXACT [GOC:TermGenie] synonym: "acetate ester formation" EXACT [GOC:TermGenie] synonym: "acetate ester synthesis" EXACT [GOC:TermGenie] synonym: "acetyl ester biosynthesis" EXACT [CHEBI:47622] synonym: "acetyl ester biosynthetic process" EXACT [CHEBI:47622] is_a: GO:1900619 ! acetate ester metabolic process is_a: GO:1901576 ! organic substance biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:47622 ! has primary output acetate ester relationship: RO:0004008 CHEBI:47622 ! has primary output acetate ester creation_date: 2012-05-16T12:30:12Z [Term] id: GO:1901071 name: glucosamine-containing compound metabolic process namespace: biological_process def: "The chemical reactions and pathways involving glucosamine-containing compounds (glucosamines)." [GOC:TermGenie] synonym: "glucosamine-containing compound metabolism" EXACT [GOC:bf] synonym: "glucosamines metabolic process" EXACT [CHEBI:24271] synonym: "glucosamines metabolism" EXACT [GOC:TermGenie] is_a: GO:0006040 ! amino sugar metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:24271 ! has primary input or output glucosamines relationship: RO:0004007 CHEBI:24271 ! has primary input or output glucosamines creation_date: 2012-07-02T03:18:04Z [Term] id: GO:1901072 name: glucosamine-containing compound catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of glucosamine-containing compounds (glucosamines)." [GOC:TermGenie] synonym: "glucosamine-containing compound breakdown" EXACT [GOC:bf] synonym: "glucosamine-containing compound catabolism" EXACT [GOC:bf] synonym: "glucosamine-containing compound degradation" EXACT [GOC:bf] synonym: "glucosamines breakdown" EXACT [GOC:TermGenie] synonym: "glucosamines catabolic process" EXACT [CHEBI:24271] synonym: "glucosamines catabolism" EXACT [GOC:TermGenie] synonym: "glucosamines degradation" EXACT [GOC:TermGenie] is_a: GO:0046348 ! amino sugar catabolic process is_a: GO:1901071 ! glucosamine-containing compound metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:24271 ! has primary input glucosamines relationship: RO:0004009 CHEBI:24271 ! has primary input glucosamines creation_date: 2012-07-02T03:18:25Z [Term] id: GO:1901073 name: glucosamine-containing compound biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of glucosamine-containing compounds (glucosamines)." [GOC:TermGenie] synonym: "glucosamine-containing compound anabolism" EXACT [GOC:bf] synonym: "glucosamine-containing compound biosynthesis" EXACT [GOC:bf] synonym: "glucosamine-containing compound formation" EXACT [GOC:bf] synonym: "glucosamine-containing compound synthesis" EXACT [GOC:bf] synonym: "glucosamines anabolism" EXACT [GOC:TermGenie] synonym: "glucosamines biosynthesis" EXACT [GOC:TermGenie] synonym: "glucosamines biosynthetic process" EXACT [CHEBI:24271] synonym: "glucosamines formation" EXACT [GOC:TermGenie] synonym: "glucosamines synthesis" EXACT [GOC:TermGenie] is_a: GO:0046349 ! amino sugar biosynthetic process is_a: GO:1901071 ! glucosamine-containing compound metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:24271 ! has primary output glucosamines relationship: RO:0004008 CHEBI:24271 ! has primary output glucosamines creation_date: 2012-07-02T03:18:33Z [Term] id: GO:1901135 name: carbohydrate derivative metabolic process namespace: biological_process def: "The chemical reactions and pathways involving carbohydrate derivative." [GOC:TermGenie] synonym: "carbohydrate derivative metabolism" EXACT [GOC:TermGenie] is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:63299 ! has primary input or output carbohydrate derivative relationship: RO:0004007 CHEBI:63299 ! has primary input or output carbohydrate derivative creation_date: 2012-07-12T04:05:09Z [Term] id: GO:1901136 name: carbohydrate derivative catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of carbohydrate derivative." [GOC:TermGenie] synonym: "carbohydrate derivative breakdown" EXACT [GOC:TermGenie] synonym: "carbohydrate derivative catabolism" EXACT [GOC:TermGenie] synonym: "carbohydrate derivative degradation" EXACT [GOC:TermGenie] is_a: GO:1901135 ! carbohydrate derivative metabolic process is_a: GO:1901575 ! organic substance catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:63299 ! has primary input carbohydrate derivative relationship: RO:0004009 CHEBI:63299 ! has primary input carbohydrate derivative creation_date: 2012-07-12T04:05:31Z [Term] id: GO:1901137 name: carbohydrate derivative biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of carbohydrate derivative." [GOC:TermGenie] synonym: "carbohydrate derivative anabolism" EXACT [GOC:TermGenie] synonym: "carbohydrate derivative biosynthesis" EXACT [GOC:TermGenie] synonym: "carbohydrate derivative formation" EXACT [GOC:TermGenie] synonym: "carbohydrate derivative synthesis" EXACT [GOC:TermGenie] is_a: GO:1901135 ! carbohydrate derivative metabolic process is_a: GO:1901576 ! organic substance biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:63299 ! has primary output carbohydrate derivative relationship: RO:0004008 CHEBI:63299 ! has primary output carbohydrate derivative creation_date: 2012-07-12T04:05:39Z [Term] id: GO:1901142 name: insulin metabolic process namespace: biological_process def: "The chemical reactions and pathways involving insulin." [GOC:TermGenie] synonym: "insulin metabolism" EXACT [GOC:TermGenie] is_a: GO:0019538 ! protein metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 PR:000009054 ! has primary input or output insulin gene translation product relationship: RO:0004007 PR:000009054 ! has primary input or output insulin gene translation product creation_date: 2012-07-13T12:32:40Z [Term] id: GO:1901143 name: insulin catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of insulin." [GOC:TermGenie] synonym: "insulin breakdown" EXACT [GOC:TermGenie] synonym: "insulin catabolism" EXACT [GOC:TermGenie] synonym: "insulin degradation" EXACT [GOC:TermGenie] is_a: GO:0030163 ! protein catabolic process is_a: GO:1901142 ! insulin metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 PR:000009054 ! has primary input insulin gene translation product relationship: RO:0004009 PR:000009054 ! has primary input insulin gene translation product creation_date: 2012-07-13T12:33:03Z [Term] id: GO:1901145 name: mesenchymal cell apoptotic process involved in nephron morphogenesis namespace: biological_process def: "Any mesenchymal cell apoptotic process that is involved in nephron morphogenesis." [GOC:mtg_apoptosis, GOC:TermGenie] is_a: GO:0060561 ! apoptotic process involved in morphogenesis is_a: GO:0097152 ! mesenchymal cell apoptotic process intersection_of: GO:0097152 ! mesenchymal cell apoptotic process intersection_of: BFO:0000050 GO:0072028 ! part of nephron morphogenesis relationship: BFO:0000050 GO:0072028 ! part of nephron morphogenesis creation_date: 2012-07-13T01:43:51Z [Term] id: GO:1901146 name: mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis namespace: biological_process def: "Any mesenchymal cell apoptotic process that is involved in mesonephric nephron morphogenesis." [GOC:mtg_apoptosis, GOC:TermGenie] is_a: GO:1901145 ! mesenchymal cell apoptotic process involved in nephron morphogenesis intersection_of: GO:0097152 ! mesenchymal cell apoptotic process intersection_of: BFO:0000050 GO:0061228 ! part of mesonephric nephron morphogenesis relationship: BFO:0000050 GO:0061228 ! part of mesonephric nephron morphogenesis creation_date: 2012-07-13T02:40:43Z [Term] id: GO:1901147 name: mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis namespace: biological_process def: "Any mesenchymal cell apoptotic process that is involved in metanephric nephron morphogenesis." [GOC:mtg_apoptosis, GOC:TermGenie] is_a: GO:1900200 ! mesenchymal cell apoptotic process involved in metanephros development is_a: GO:1901145 ! mesenchymal cell apoptotic process involved in nephron morphogenesis intersection_of: GO:0097152 ! mesenchymal cell apoptotic process intersection_of: BFO:0000050 GO:0072273 ! part of metanephric nephron morphogenesis relationship: BFO:0000050 GO:0072273 ! part of metanephric nephron morphogenesis creation_date: 2012-07-13T02:41:12Z [Term] id: GO:1901148 name: gene expression involved in extracellular matrix organization namespace: biological_process def: "Any gene expression that is involved in extracellular matrix organization. Gene expression includes both transcription to produce an RNA transcript, and the translation of that mRNA into protein. Protein maturation is included in gene expression when required to form an active form of a product from an inactive precursor form." [GOC:pg, GOC:TermGenie, PMID:18668558] synonym: "expression of extracellular matrix proteins" EXACT [GOC:bf] is_a: GO:0010467 ! gene expression intersection_of: GO:0010467 ! gene expression intersection_of: BFO:0000050 GO:0030198 ! part of extracellular matrix organization relationship: BFO:0000050 GO:0030198 ! part of extracellular matrix organization creation_date: 2012-07-16T03:29:30Z [Term] id: GO:1901160 name: primary amino compound metabolic process namespace: biological_process def: "The chemical reactions and pathways involving primary amino compound." [GOC:TermGenie] synonym: "primary amino compound metabolism" EXACT [GOC:TermGenie] is_a: GO:1901564 ! organonitrogen compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:50994 ! has primary input or output primary amino compound relationship: RO:0004007 CHEBI:50994 ! has primary input or output primary amino compound creation_date: 2012-07-18T04:44:39Z [Term] id: GO:1901161 name: primary amino compound catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of primary amino compound." [GOC:TermGenie] synonym: "primary amino compound breakdown" EXACT [GOC:TermGenie] synonym: "primary amino compound catabolism" EXACT [GOC:TermGenie] synonym: "primary amino compound degradation" EXACT [GOC:TermGenie] is_a: GO:1901160 ! primary amino compound metabolic process is_a: GO:1901565 ! organonitrogen compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:50994 ! has primary input primary amino compound relationship: RO:0004009 CHEBI:50994 ! has primary input primary amino compound creation_date: 2012-07-18T04:45:06Z [Term] id: GO:1901162 name: primary amino compound biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of primary amino compound." [GOC:TermGenie] synonym: "primary amino compound anabolism" EXACT [GOC:TermGenie] synonym: "primary amino compound biosynthesis" EXACT [GOC:TermGenie] synonym: "primary amino compound formation" EXACT [GOC:TermGenie] synonym: "primary amino compound synthesis" EXACT [GOC:TermGenie] is_a: GO:1901160 ! primary amino compound metabolic process is_a: GO:1901566 ! organonitrogen compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:50994 ! has primary output primary amino compound relationship: RO:0004008 CHEBI:50994 ! has primary output primary amino compound creation_date: 2012-07-18T04:45:14Z [Term] id: GO:1901163 name: regulation of trophoblast cell migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of trophoblast cell migration." [GOC:BHF, GOC:TermGenie] is_a: GO:0030334 ! regulation of cell migration is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0061450 ! regulates (processual) trophoblast cell migration relationship: RO:0002211 GO:0061450 ! regulates (processual) trophoblast cell migration creation_date: 2012-07-19T07:53:06Z [Term] id: GO:1901164 name: negative regulation of trophoblast cell migration namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of trophoblast cell migration." [GOC:BHF, GOC:TermGenie] synonym: "down regulation of trophoblast cell migration" EXACT [GOC:TermGenie] synonym: "down-regulation of trophoblast cell migration" EXACT [GOC:TermGenie] synonym: "downregulation of trophoblast cell migration" EXACT [GOC:TermGenie] is_a: GO:0030336 ! negative regulation of cell migration is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1901163 ! regulation of trophoblast cell migration is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0061450 ! negatively regulates trophoblast cell migration relationship: RO:0002212 GO:0061450 ! negatively regulates trophoblast cell migration creation_date: 2012-07-19T07:53:28Z [Term] id: GO:1901165 name: positive regulation of trophoblast cell migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of trophoblast cell migration." [GOC:BHF, GOC:TermGenie] synonym: "up regulation of trophoblast cell migration" EXACT [GOC:TermGenie] synonym: "up-regulation of trophoblast cell migration" EXACT [GOC:TermGenie] synonym: "upregulation of trophoblast cell migration" EXACT [GOC:TermGenie] is_a: GO:0030335 ! positive regulation of cell migration is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1901163 ! regulation of trophoblast cell migration is_a: GO:2000243 ! positive regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0061450 ! positively regulates trophoblast cell migration relationship: RO:0002213 GO:0061450 ! positively regulates trophoblast cell migration creation_date: 2012-07-19T07:53:35Z [Term] id: GO:1901166 name: neural crest cell migration involved in autonomic nervous system development namespace: biological_process def: "Any neural crest cell migration that is involved in autonomic nervous system development." [GOC:BHF, GOC:TermGenie] is_a: GO:0001755 ! neural crest cell migration intersection_of: GO:0001755 ! neural crest cell migration intersection_of: BFO:0000050 GO:0048483 ! part of autonomic nervous system development relationship: BFO:0000050 GO:0048483 ! part of autonomic nervous system development creation_date: 2012-07-19T08:39:56Z [Term] id: GO:1901190 name: regulation of formation of translation initiation ternary complex namespace: biological_process def: "Any process that modulates the frequency, rate or extent of formation of translation initiation ternary complex." [GOC:TermGenie] synonym: "regulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] is_a: GO:0043254 ! regulation of protein-containing complex assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001677 ! regulates (processual) formation of translation initiation ternary complex relationship: RO:0002211 GO:0001677 ! regulates (processual) formation of translation initiation ternary complex creation_date: 2012-07-25T02:26:58Z [Term] id: GO:1901191 name: negative regulation of formation of translation initiation ternary complex namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of formation of translation initiation ternary complex." [GOC:TermGenie] synonym: "down regulation of formation of translation initiation ternary complex" EXACT [GOC:TermGenie] synonym: "down regulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of formation of translation initiation ternary complex" EXACT [GOC:TermGenie] synonym: "down-regulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] synonym: "downregulation of formation of translation initiation ternary complex" EXACT [GOC:TermGenie] synonym: "downregulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] synonym: "inhibition of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] synonym: "negative regulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] is_a: GO:0031333 ! negative regulation of protein-containing complex assembly is_a: GO:0045947 ! negative regulation of translational initiation is_a: GO:1901190 ! regulation of formation of translation initiation ternary complex intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001677 ! negatively regulates formation of translation initiation ternary complex relationship: RO:0002212 GO:0001677 ! negatively regulates formation of translation initiation ternary complex creation_date: 2012-07-25T02:27:21Z [Term] id: GO:1901192 name: positive regulation of formation of translation initiation ternary complex namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of formation of translation initiation ternary complex." [GOC:TermGenie] synonym: "activation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] synonym: "positive regulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] synonym: "up regulation of formation of translation initiation ternary complex" EXACT [GOC:TermGenie] synonym: "up regulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] synonym: "up-regulation of formation of translation initiation ternary complex" EXACT [GOC:TermGenie] synonym: "up-regulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] synonym: "upregulation of formation of translation initiation ternary complex" EXACT [GOC:TermGenie] synonym: "upregulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] is_a: GO:0031334 ! positive regulation of protein-containing complex assembly is_a: GO:1901190 ! regulation of formation of translation initiation ternary complex intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001677 ! positively regulates formation of translation initiation ternary complex relationship: RO:0002213 GO:0001677 ! positively regulates formation of translation initiation ternary complex creation_date: 2012-07-25T02:27:29Z [Term] id: GO:1901201 name: regulation of extracellular matrix assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of extracellular matrix assembly." [GOC:BHF, GOC:TermGenie] is_a: GO:0044087 ! regulation of cellular component biogenesis is_a: GO:1903053 ! regulation of extracellular matrix organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0085029 ! regulates (processual) extracellular matrix assembly relationship: RO:0002211 GO:0085029 ! regulates (processual) extracellular matrix assembly creation_date: 2012-07-27T04:04:00Z [Term] id: GO:1901202 name: negative regulation of extracellular matrix assembly namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix assembly." [GOC:BHF, GOC:TermGenie] synonym: "down regulation of extracellular matrix assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of extracellular matrix assembly" EXACT [GOC:TermGenie] synonym: "downregulation of extracellular matrix assembly" EXACT [GOC:TermGenie] is_a: GO:1901201 ! regulation of extracellular matrix assembly is_a: GO:1903054 ! negative regulation of extracellular matrix organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0085029 ! negatively regulates extracellular matrix assembly relationship: RO:0002212 GO:0085029 ! negatively regulates extracellular matrix assembly creation_date: 2012-07-27T04:04:24Z [Term] id: GO:1901203 name: positive regulation of extracellular matrix assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of extracellular matrix assembly." [GOC:BHF, GOC:TermGenie] synonym: "up regulation of extracellular matrix assembly" EXACT [GOC:TermGenie] synonym: "up-regulation of extracellular matrix assembly" EXACT [GOC:TermGenie] synonym: "upregulation of extracellular matrix assembly" EXACT [GOC:TermGenie] is_a: GO:0044089 ! positive regulation of cellular component biogenesis is_a: GO:1901201 ! regulation of extracellular matrix assembly is_a: GO:1903055 ! positive regulation of extracellular matrix organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0085029 ! positively regulates extracellular matrix assembly relationship: RO:0002213 GO:0085029 ! positively regulates extracellular matrix assembly creation_date: 2012-07-27T04:04:32Z [Term] id: GO:1901210 name: regulation of cardiac chamber formation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac chamber formation." [GOC:BHF, GOC:TermGenie] synonym: "regulation of heart chamber formation" EXACT [GOC:TermGenie] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003207 ! regulates (processual) cardiac chamber formation relationship: RO:0002211 GO:0003207 ! regulates (processual) cardiac chamber formation creation_date: 2012-07-31T07:18:35Z [Term] id: GO:1901211 name: negative regulation of cardiac chamber formation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber formation." [GOC:BHF, GOC:TermGenie] synonym: "down regulation of cardiac chamber formation" EXACT [GOC:TermGenie] synonym: "down regulation of heart chamber formation" EXACT [GOC:TermGenie] synonym: "down-regulation of cardiac chamber formation" EXACT [GOC:TermGenie] synonym: "down-regulation of heart chamber formation" EXACT [GOC:TermGenie] synonym: "downregulation of cardiac chamber formation" EXACT [GOC:TermGenie] synonym: "downregulation of heart chamber formation" EXACT [GOC:TermGenie] synonym: "inhibition of heart chamber formation" EXACT [GOC:TermGenie] synonym: "negative regulation of heart chamber formation" EXACT [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:1901210 ! regulation of cardiac chamber formation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0003207 ! negatively regulates cardiac chamber formation relationship: RO:0002212 GO:0003207 ! negatively regulates cardiac chamber formation creation_date: 2012-07-31T07:18:57Z [Term] id: GO:1901212 name: positive regulation of cardiac chamber formation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cardiac chamber formation." [GOC:BHF, GOC:TermGenie] synonym: "activation of heart chamber formation" EXACT [GOC:TermGenie] synonym: "positive regulation of heart chamber formation" EXACT [GOC:TermGenie] synonym: "up regulation of cardiac chamber formation" EXACT [GOC:TermGenie] synonym: "up regulation of heart chamber formation" EXACT [GOC:TermGenie] synonym: "up-regulation of cardiac chamber formation" EXACT [GOC:TermGenie] synonym: "up-regulation of heart chamber formation" EXACT [GOC:TermGenie] synonym: "upregulation of cardiac chamber formation" EXACT [GOC:TermGenie] synonym: "upregulation of heart chamber formation" EXACT [GOC:TermGenie] is_a: GO:1901210 ! regulation of cardiac chamber formation is_a: GO:1901221 ! positive regulation of cardiac chamber morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0003207 ! positively regulates cardiac chamber formation relationship: RO:0002213 GO:0003207 ! positively regulates cardiac chamber formation creation_date: 2012-07-31T07:19:05Z [Term] id: GO:1901219 name: regulation of cardiac chamber morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac chamber morphogenesis." [GOC:BHF, GOC:TermGenie] synonym: "regulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] is_a: GO:2000826 ! regulation of heart morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003206 ! regulates (processual) cardiac chamber morphogenesis relationship: RO:0002211 GO:0003206 ! regulates (processual) cardiac chamber morphogenesis creation_date: 2012-08-06T17:59:11Z [Term] id: GO:1901220 name: negative regulation of cardiac chamber morphogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber morphogenesis." [GOC:BHF, GOC:TermGenie] synonym: "down regulation of cardiac chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "down regulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of cardiac chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of cardiac chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "negative regulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:1901219 ! regulation of cardiac chamber morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0003206 ! negatively regulates cardiac chamber morphogenesis relationship: RO:0002212 GO:0003206 ! negatively regulates cardiac chamber morphogenesis creation_date: 2012-08-06T17:59:34Z [Term] id: GO:1901221 name: positive regulation of cardiac chamber morphogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cardiac chamber morphogenesis." [GOC:BHF, GOC:TermGenie] synonym: "positive regulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of cardiac chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of cardiac chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of cardiac chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:1901219 ! regulation of cardiac chamber morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0003206 ! positively regulates cardiac chamber morphogenesis relationship: RO:0002213 GO:0003206 ! positively regulates cardiac chamber morphogenesis creation_date: 2012-08-06T17:59:42Z [Term] id: GO:1901246 name: regulation of lung ciliated cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of lung ciliated cell differentiation." [GOC:BHF, GOC:TermGenie] is_a: GO:0030856 ! regulation of epithelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0061141 ! regulates (processual) lung ciliated cell differentiation relationship: RO:0002211 GO:0061141 ! regulates (processual) lung ciliated cell differentiation creation_date: 2012-08-08T08:58:34Z [Term] id: GO:1901247 name: negative regulation of lung ciliated cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of lung ciliated cell differentiation." [GOC:BHF, GOC:TermGenie] synonym: "down regulation of lung ciliated cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of lung ciliated cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of lung ciliated cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0030857 ! negative regulation of epithelial cell differentiation is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1901246 ! regulation of lung ciliated cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0061141 ! negatively regulates lung ciliated cell differentiation relationship: RO:0002212 GO:0061141 ! negatively regulates lung ciliated cell differentiation creation_date: 2012-08-08T08:58:58Z [Term] id: GO:1901248 name: positive regulation of lung ciliated cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of lung ciliated cell differentiation." [GOC:BHF, GOC:TermGenie] synonym: "up regulation of lung ciliated cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of lung ciliated cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of lung ciliated cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0030858 ! positive regulation of epithelial cell differentiation is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1901246 ! regulation of lung ciliated cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0061141 ! positively regulates lung ciliated cell differentiation relationship: RO:0002213 GO:0061141 ! positively regulates lung ciliated cell differentiation creation_date: 2012-08-08T08:59:05Z [Term] id: GO:1901264 name: carbohydrate derivative transport namespace: biological_process def: "The directed movement of a carbohydrate derivative into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:bf, GOC:jl, GOC:TermGenie] is_a: GO:0071702 ! organic substance transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:63299 ! has primary input carbohydrate derivative relationship: RO:0004009 CHEBI:63299 ! has primary input carbohydrate derivative creation_date: 2012-08-16T14:51:22Z [Term] id: GO:1901317 name: regulation of flagellated sperm motility namespace: biological_process def: "Any process that modulates the frequency, rate or extent of flagellated sperm motility." [GOC:cilia, GOC:krc, GOC:TermGenie] is_a: GO:0060295 ! regulation of cilium movement involved in cell motility is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030317 ! regulates (processual) flagellated sperm motility relationship: RO:0002211 GO:0030317 ! regulates (processual) flagellated sperm motility creation_date: 2012-08-22T20:50:14Z [Term] id: GO:1901318 name: negative regulation of flagellated sperm motility namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of flagellated sperm motility." [GOC:cilia, GOC:krc, GOC:TermGenie] is_a: GO:0003354 ! negative regulation of cilium movement is_a: GO:1901317 ! regulation of flagellated sperm motility is_a: GO:1902020 ! negative regulation of cilium-dependent cell motility is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030317 ! negatively regulates flagellated sperm motility relationship: RO:0002212 GO:0030317 ! negatively regulates flagellated sperm motility creation_date: 2012-08-22T20:50:35Z [Term] id: GO:1901342 name: regulation of vasculature development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of vasculature development." [GOC:TermGenie] is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001944 ! regulates (processual) vasculature development relationship: RO:0002211 GO:0001944 ! regulates (processual) vasculature development creation_date: 2012-09-06T09:16:15Z [Term] id: GO:1901343 name: negative regulation of vasculature development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of vasculature development." [GOC:TermGenie] synonym: "down regulation of vasculature development" EXACT [GOC:TermGenie] synonym: "down-regulation of vasculature development" EXACT [GOC:TermGenie] synonym: "downregulation of vasculature development" EXACT [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1901342 ! regulation of vasculature development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001944 ! negatively regulates vasculature development relationship: RO:0002212 GO:0001944 ! negatively regulates vasculature development creation_date: 2012-09-06T09:17:24Z [Term] id: GO:1901360 name: organic cyclic compound metabolic process namespace: biological_process def: "The chemical reactions and pathways involving organic cyclic compound." [GOC:TermGenie] synonym: "organic cyclic compound metabolism" EXACT [GOC:TermGenie] is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:33832 ! has primary input or output organic cyclic compound relationship: RO:0004007 CHEBI:33832 ! has primary input or output organic cyclic compound creation_date: 2012-09-14T09:03:51Z [Term] id: GO:1901361 name: organic cyclic compound catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of organic cyclic compound." [GOC:TermGenie] synonym: "organic cyclic compound breakdown" EXACT [GOC:TermGenie] synonym: "organic cyclic compound catabolism" EXACT [GOC:TermGenie] synonym: "organic cyclic compound degradation" EXACT [GOC:TermGenie] is_a: GO:1901360 ! organic cyclic compound metabolic process is_a: GO:1901575 ! organic substance catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:33832 ! has primary input organic cyclic compound relationship: RO:0004009 CHEBI:33832 ! has primary input organic cyclic compound creation_date: 2012-09-14T09:05:04Z [Term] id: GO:1901362 name: organic cyclic compound biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of organic cyclic compound." [GOC:TermGenie] synonym: "organic cyclic compound anabolism" EXACT [GOC:TermGenie] synonym: "organic cyclic compound biosynthesis" EXACT [GOC:TermGenie] synonym: "organic cyclic compound formation" EXACT [GOC:TermGenie] synonym: "organic cyclic compound synthesis" EXACT [GOC:TermGenie] is_a: GO:1901360 ! organic cyclic compound metabolic process is_a: GO:1901576 ! organic substance biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:33832 ! has primary output organic cyclic compound relationship: RO:0004008 CHEBI:33832 ! has primary output organic cyclic compound creation_date: 2012-09-14T09:05:22Z [Term] id: GO:1901374 name: acetate ester transport namespace: biological_process def: "The directed movement of an acetate ester into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:TermGenie] is_a: GO:0071702 ! organic substance transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:47622 ! has primary input acetate ester relationship: RO:0004009 CHEBI:47622 ! has primary input acetate ester creation_date: 2012-09-28T10:42:13Z [Term] id: GO:1901375 name: acetate ester transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of an acetate ester from one side of a membrane to the other." [GOC:TermGenie] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:47622 ! has primary input acetate ester relationship: BFO:0000050 GO:1901374 ! part of acetate ester transport relationship: RO:0004009 CHEBI:47622 ! has primary input acetate ester creation_date: 2012-09-28T10:47:08Z [Term] id: GO:1901382 name: regulation of chorionic trophoblast cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of chorionic trophoblast cell proliferation." [GOC:BHF, GOC:TermGenie] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0097360 ! regulates (processual) chorionic trophoblast cell proliferation relationship: RO:0002211 GO:0097360 ! regulates (processual) chorionic trophoblast cell proliferation creation_date: 2012-10-01T10:03:13Z [Term] id: GO:1901383 name: negative regulation of chorionic trophoblast cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of chorionic trophoblast cell proliferation." [GOC:BHF, GOC:TermGenie] synonym: "down regulation of chorionic trophoblast cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of chorionic trophoblast cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of chorionic trophoblast cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:1901382 ! regulation of chorionic trophoblast cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0097360 ! negatively regulates chorionic trophoblast cell proliferation relationship: RO:0002212 GO:0097360 ! negatively regulates chorionic trophoblast cell proliferation creation_date: 2012-10-01T10:04:23Z [Term] id: GO:1901384 name: positive regulation of chorionic trophoblast cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of chorionic trophoblast cell proliferation." [GOC:BHF, GOC:TermGenie] synonym: "up regulation of chorionic trophoblast cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of chorionic trophoblast cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of chorionic trophoblast cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:1901382 ! regulation of chorionic trophoblast cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0097360 ! positively regulates chorionic trophoblast cell proliferation relationship: RO:0002213 GO:0097360 ! positively regulates chorionic trophoblast cell proliferation creation_date: 2012-10-01T10:04:41Z [Term] id: GO:1901401 name: regulation of tetrapyrrole metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of tetrapyrrole metabolic process." [GOC:mengo_curators, GOC:TermGenie] synonym: "regulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] is_a: GO:0031323 ! regulation of cellular metabolic process is_a: GO:0051171 ! regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0033013 ! regulates (processual) tetrapyrrole metabolic process relationship: RO:0002211 GO:0033013 ! regulates (processual) tetrapyrrole metabolic process creation_date: 2012-10-01T14:34:03Z [Term] id: GO:1901402 name: negative regulation of tetrapyrrole metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole metabolic process." [GOC:mengo_curators, GOC:TermGenie] synonym: "down regulation of tetrapyrrole metabolic process" EXACT [GOC:TermGenie] synonym: "down regulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of tetrapyrrole metabolic process" EXACT [GOC:TermGenie] synonym: "down-regulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] synonym: "downregulation of tetrapyrrole metabolic process" EXACT [GOC:TermGenie] synonym: "downregulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] synonym: "inhibition of tetrapyrrole metabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] is_a: GO:0031324 ! negative regulation of cellular metabolic process is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process is_a: GO:1901401 ! regulation of tetrapyrrole metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0033013 ! negatively regulates tetrapyrrole metabolic process relationship: RO:0002212 GO:0033013 ! negatively regulates tetrapyrrole metabolic process creation_date: 2012-10-01T14:35:11Z [Term] id: GO:1901403 name: positive regulation of tetrapyrrole metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of tetrapyrrole metabolic process." [GOC:mengo_curators, GOC:TermGenie] synonym: "activation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] synonym: "up regulation of tetrapyrrole metabolic process" EXACT [GOC:TermGenie] synonym: "up regulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of tetrapyrrole metabolic process" EXACT [GOC:TermGenie] synonym: "up-regulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] synonym: "upregulation of tetrapyrrole metabolic process" EXACT [GOC:TermGenie] synonym: "upregulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] is_a: GO:0031325 ! positive regulation of cellular metabolic process is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process is_a: GO:1901401 ! regulation of tetrapyrrole metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0033013 ! positively regulates tetrapyrrole metabolic process relationship: RO:0002213 GO:0033013 ! positively regulates tetrapyrrole metabolic process creation_date: 2012-10-01T14:35:29Z [Term] id: GO:1901404 name: regulation of tetrapyrrole catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of tetrapyrrole catabolic process." [GOC:mengo_curators, GOC:TermGenie] synonym: "regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] is_a: GO:0031329 ! regulation of cellular catabolic process is_a: GO:1901401 ! regulation of tetrapyrrole metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0033015 ! regulates (processual) tetrapyrrole catabolic process relationship: RO:0002211 GO:0033015 ! regulates (processual) tetrapyrrole catabolic process creation_date: 2012-10-01T14:38:12Z [Term] id: GO:1901405 name: negative regulation of tetrapyrrole catabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole catabolic process." [GOC:mengo_curators, GOC:TermGenie] synonym: "down regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "down regulation of tetrapyrrole catabolic process" EXACT [GOC:TermGenie] synonym: "down regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "down regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] synonym: "down-regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "down-regulation of tetrapyrrole catabolic process" EXACT [GOC:TermGenie] synonym: "down-regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] synonym: "downregulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "downregulation of tetrapyrrole catabolic process" EXACT [GOC:TermGenie] synonym: "downregulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "downregulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] synonym: "inhibition of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "inhibition of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "inhibition of tetrapyrrole degradation" EXACT [GOC:TermGenie] synonym: "negative regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "negative regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] is_a: GO:0031330 ! negative regulation of cellular catabolic process is_a: GO:1901402 ! negative regulation of tetrapyrrole metabolic process is_a: GO:1901404 ! regulation of tetrapyrrole catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0033015 ! negatively regulates tetrapyrrole catabolic process relationship: RO:0002212 GO:0033015 ! negatively regulates tetrapyrrole catabolic process creation_date: 2012-10-01T14:39:22Z [Term] id: GO:1901406 name: positive regulation of tetrapyrrole catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of tetrapyrrole catabolic process." [GOC:mengo_curators, GOC:TermGenie] synonym: "activation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "activation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "activation of tetrapyrrole degradation" EXACT [GOC:TermGenie] synonym: "positive regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "positive regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] synonym: "up regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "up regulation of tetrapyrrole catabolic process" EXACT [GOC:TermGenie] synonym: "up regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "up regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] synonym: "up-regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "up-regulation of tetrapyrrole catabolic process" EXACT [GOC:TermGenie] synonym: "up-regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] synonym: "upregulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "upregulation of tetrapyrrole catabolic process" EXACT [GOC:TermGenie] synonym: "upregulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "upregulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] is_a: GO:0031331 ! positive regulation of cellular catabolic process is_a: GO:1901403 ! positive regulation of tetrapyrrole metabolic process is_a: GO:1901404 ! regulation of tetrapyrrole catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0033015 ! positively regulates tetrapyrrole catabolic process relationship: RO:0002213 GO:0033015 ! positively regulates tetrapyrrole catabolic process creation_date: 2012-10-01T14:39:40Z [Term] id: GO:1901457 name: regulation of response to acetate namespace: biological_process def: "Any process that modulates the frequency, rate or extent of response to acetate." [GOC:mengo_curators, GOC:TermGenie] is_a: GO:0048583 ! regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0010034 ! regulates (processual) response to acetate relationship: RO:0002211 GO:0010034 ! regulates (processual) response to acetate creation_date: 2012-10-02T14:25:06Z [Term] id: GO:1901458 name: negative regulation of response to acetate namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of response to acetate." [GOC:mengo_curators, GOC:TermGenie] synonym: "down regulation of response to acetate" EXACT [GOC:TermGenie] synonym: "down-regulation of response to acetate" EXACT [GOC:TermGenie] synonym: "downregulation of response to acetate" EXACT [GOC:TermGenie] is_a: GO:0048585 ! negative regulation of response to stimulus is_a: GO:1901457 ! regulation of response to acetate intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0010034 ! negatively regulates response to acetate relationship: RO:0002212 GO:0010034 ! negatively regulates response to acetate creation_date: 2012-10-02T14:26:15Z [Term] id: GO:1901459 name: positive regulation of response to acetate namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of response to acetate." [GOC:mengo_curators, GOC:TermGenie] synonym: "up regulation of response to acetate" EXACT [GOC:TermGenie] synonym: "up-regulation of response to acetate" EXACT [GOC:TermGenie] synonym: "upregulation of response to acetate" EXACT [GOC:TermGenie] is_a: GO:0048584 ! positive regulation of response to stimulus is_a: GO:1901457 ! regulation of response to acetate intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0010034 ! positively regulates response to acetate relationship: RO:0002213 GO:0010034 ! positively regulates response to acetate creation_date: 2012-10-02T14:26:34Z [Term] id: GO:1901463 name: regulation of tetrapyrrole biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of tetrapyrrole biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] synonym: "regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "regulation of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] is_a: GO:0031326 ! regulation of cellular biosynthetic process is_a: GO:1901401 ! regulation of tetrapyrrole metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0033014 ! regulates (processual) tetrapyrrole biosynthetic process relationship: RO:0002211 GO:0033014 ! regulates (processual) tetrapyrrole biosynthetic process creation_date: 2012-10-02T14:34:14Z [Term] id: GO:1901464 name: negative regulation of tetrapyrrole biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] synonym: "down regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "down regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "down regulation of tetrapyrrole biosynthetic process" EXACT [GOC:TermGenie] synonym: "down regulation of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "down regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of tetrapyrrole biosynthetic process" EXACT [GOC:TermGenie] synonym: "down-regulation of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "down-regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] synonym: "downregulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "downregulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "downregulation of tetrapyrrole biosynthetic process" EXACT [GOC:TermGenie] synonym: "downregulation of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "downregulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] synonym: "inhibition of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "inhibition of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "inhibition of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "inhibition of tetrapyrrole synthesis" EXACT [GOC:TermGenie] synonym: "negative regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "negative regulation of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "negative regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] is_a: GO:0031327 ! negative regulation of cellular biosynthetic process is_a: GO:1901402 ! negative regulation of tetrapyrrole metabolic process is_a: GO:1901463 ! regulation of tetrapyrrole biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0033014 ! negatively regulates tetrapyrrole biosynthetic process relationship: RO:0002212 GO:0033014 ! negatively regulates tetrapyrrole biosynthetic process creation_date: 2012-10-02T14:35:26Z [Term] id: GO:1901465 name: positive regulation of tetrapyrrole biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] synonym: "activation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "activation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "activation of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "activation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] synonym: "positive regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "positive regulation of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "positive regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] synonym: "up regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "up regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "up regulation of tetrapyrrole biosynthetic process" EXACT [GOC:TermGenie] synonym: "up regulation of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "up regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of tetrapyrrole biosynthetic process" EXACT [GOC:TermGenie] synonym: "up-regulation of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "up-regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] synonym: "upregulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "upregulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "upregulation of tetrapyrrole biosynthetic process" EXACT [GOC:TermGenie] synonym: "upregulation of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "upregulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] is_a: GO:0031328 ! positive regulation of cellular biosynthetic process is_a: GO:1901403 ! positive regulation of tetrapyrrole metabolic process is_a: GO:1901463 ! regulation of tetrapyrrole biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0033014 ! positively regulates tetrapyrrole biosynthetic process relationship: RO:0002213 GO:0033014 ! positively regulates tetrapyrrole biosynthetic process creation_date: 2012-10-02T14:35:43Z [Term] id: GO:1901505 name: carbohydrate derivative transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of carbohydrate derivative from one side of a membrane to the other." [GOC:pr, GOC:TermGenie] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:63299 ! has primary input carbohydrate derivative relationship: BFO:0000050 GO:1901264 ! part of carbohydrate derivative transport relationship: RO:0004009 CHEBI:63299 ! has primary input carbohydrate derivative creation_date: 2012-10-17T10:31:22Z [Term] id: GO:1901509 name: regulation of endothelial tube morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of endothelial tube morphogenesis." [GOC:dph, GOC:TermGenie] is_a: GO:1905330 ! regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0061154 ! regulates (processual) endothelial tube morphogenesis relationship: RO:0002211 GO:0061154 ! regulates (processual) endothelial tube morphogenesis creation_date: 2012-10-17T14:30:40Z [Term] id: GO:1901532 name: regulation of hematopoietic progenitor cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of hematopoietic progenitor cell differentiation." [GOC:BHF, GOC:rl, GOC:TermGenie] synonym: "regulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "regulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "regulation of hemopoietic progenitor cell differentiation" EXACT [] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002244 ! regulates (processual) hematopoietic progenitor cell differentiation relationship: RO:0002211 GO:0002244 ! regulates (processual) hematopoietic progenitor cell differentiation creation_date: 2012-10-24T11:23:01Z [Term] id: GO:1901533 name: negative regulation of hematopoietic progenitor cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic progenitor cell differentiation." [GOC:BHF, GOC:rl, GOC:TermGenie] synonym: "down regulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of hemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of hemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of hemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "negative regulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "negative regulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "negative regulation of hemopoietic progenitor cell differentiation" EXACT [] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:1901532 ! regulation of hematopoietic progenitor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002244 ! negatively regulates hematopoietic progenitor cell differentiation relationship: RO:0002212 GO:0002244 ! negatively regulates hematopoietic progenitor cell differentiation creation_date: 2012-10-24T11:23:06Z [Term] id: GO:1901534 name: positive regulation of hematopoietic progenitor cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of hematopoietic progenitor cell differentiation." [GOC:BHF, GOC:rl, GOC:TermGenie] synonym: "activation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "activation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "positive regulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "positive regulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "positive regulation of hemopoietic progenitor cell differentiation" EXACT [] synonym: "up regulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of hemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of hemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of hemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:1901532 ! regulation of hematopoietic progenitor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002244 ! positively regulates hematopoietic progenitor cell differentiation relationship: RO:0002213 GO:0002244 ! positively regulates hematopoietic progenitor cell differentiation creation_date: 2012-10-24T11:23:14Z [Term] id: GO:1901550 name: regulation of endothelial cell development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of endothelial cell development." [GOC:pr, GOC:TermGenie, PMID:19470579] is_a: GO:0045601 ! regulation of endothelial cell differentiation is_a: GO:0060284 ! regulation of cell development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001885 ! regulates (processual) endothelial cell development relationship: RO:0002211 GO:0001885 ! regulates (processual) endothelial cell development creation_date: 2012-10-30T12:59:50Z [Term] id: GO:1901551 name: negative regulation of endothelial cell development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell development." [GOC:pr, GOC:TermGenie, PMID:19470579] synonym: "down regulation of endothelial cell development" EXACT [GOC:TermGenie] synonym: "down-regulation of endothelial cell development" EXACT [GOC:TermGenie] synonym: "downregulation of endothelial cell development" EXACT [GOC:TermGenie] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0045602 ! negative regulation of endothelial cell differentiation is_a: GO:1901550 ! regulation of endothelial cell development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001885 ! negatively regulates endothelial cell development relationship: RO:0002212 GO:0001885 ! negatively regulates endothelial cell development creation_date: 2012-10-30T12:59:54Z [Term] id: GO:1901552 name: positive regulation of endothelial cell development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of endothelial cell development." [GOC:pr, GOC:TermGenie, PMID:19470579] synonym: "up regulation of endothelial cell development" EXACT [GOC:TermGenie] synonym: "up-regulation of endothelial cell development" EXACT [GOC:TermGenie] synonym: "upregulation of endothelial cell development" EXACT [GOC:TermGenie] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:1901550 ! regulation of endothelial cell development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001885 ! positively regulates endothelial cell development relationship: RO:0002213 GO:0001885 ! positively regulates endothelial cell development creation_date: 2012-10-30T12:59:58Z [Term] id: GO:1901564 name: organonitrogen compound metabolic process namespace: biological_process def: "The chemical reactions and pathways involving organonitrogen compound." [GOC:pr, GOC:TermGenie] synonym: "organonitrogen compound metabolism" EXACT [GOC:TermGenie] is_a: GO:0006807 ! nitrogen compound metabolic process is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:35352 ! has primary input or output organonitrogen compound relationship: RO:0004007 CHEBI:35352 ! has primary input or output organonitrogen compound creation_date: 2012-11-04T15:17:52Z [Term] id: GO:1901565 name: organonitrogen compound catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of organonitrogen compound." [GOC:pr, GOC:TermGenie] synonym: "organonitrogen compound breakdown" EXACT [GOC:TermGenie] synonym: "organonitrogen compound catabolism" EXACT [GOC:TermGenie] synonym: "organonitrogen compound degradation" EXACT [GOC:TermGenie] is_a: GO:1901564 ! organonitrogen compound metabolic process is_a: GO:1901575 ! organic substance catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:35352 ! has primary input organonitrogen compound relationship: RO:0004009 CHEBI:35352 ! has primary input organonitrogen compound creation_date: 2012-11-04T15:17:56Z [Term] id: GO:1901566 name: organonitrogen compound biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of organonitrogen compound." [GOC:pr, GOC:TermGenie] synonym: "organonitrogen compound anabolism" EXACT [GOC:TermGenie] synonym: "organonitrogen compound biosynthesis" EXACT [GOC:TermGenie] synonym: "organonitrogen compound formation" EXACT [GOC:TermGenie] synonym: "organonitrogen compound synthesis" EXACT [GOC:TermGenie] is_a: GO:1901564 ! organonitrogen compound metabolic process is_a: GO:1901576 ! organic substance biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:35352 ! has primary output organonitrogen compound relationship: RO:0004008 CHEBI:35352 ! has primary output organonitrogen compound creation_date: 2012-11-04T15:18:00Z [Term] id: GO:1901575 name: organic substance catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of an organic substance, any molecular entity containing carbon." [GOC:pr, GOC:TermGenie] synonym: "organic molecular entity breakdown" EXACT [GOC:TermGenie] synonym: "organic molecular entity catabolic process" EXACT [] synonym: "organic molecular entity catabolism" EXACT [GOC:TermGenie] synonym: "organic molecular entity degradation" EXACT [GOC:TermGenie] synonym: "organic substance breakdown" EXACT [] synonym: "organic substance catabolism" EXACT [] synonym: "organic substance degradation" EXACT [] is_a: GO:0009056 ! catabolic process is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:50860 ! has primary input organic molecular entity relationship: RO:0004009 CHEBI:50860 ! has primary input organic molecular entity creation_date: 2012-11-05T11:04:36Z [Term] id: GO:1901576 name: organic substance biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of an organic substance, any molecular entity containing carbon." [GOC:pr, GOC:TermGenie] synonym: "organic molecular entity anabolism" EXACT [GOC:TermGenie] synonym: "organic molecular entity biosynthesis" EXACT [GOC:TermGenie] synonym: "organic molecular entity biosynthetic process" EXACT [] synonym: "organic molecular entity formation" EXACT [GOC:TermGenie] synonym: "organic molecular entity synthesis" EXACT [GOC:TermGenie] synonym: "organic substance anabolism" EXACT [] synonym: "organic substance biosynthesis" EXACT [] synonym: "organic substance formation" EXACT [] synonym: "organic substance synthesis" EXACT [] is_a: GO:0009058 ! biosynthetic process is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:50860 ! has primary output organic molecular entity relationship: RO:0004008 CHEBI:50860 ! has primary output organic molecular entity creation_date: 2012-11-05T11:04:40Z [Term] id: GO:1901605 name: alpha-amino acid metabolic process namespace: biological_process def: "The chemical reactions and pathways involving an alpha-amino acid." [GOC:TermGenie] synonym: "alpha-amino acid metabolism" EXACT [GOC:TermGenie] is_a: GO:0006520 ! amino acid metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:78608 ! has primary input or output alpha-amino acid zwitterion relationship: RO:0004007 CHEBI:78608 ! has primary input or output alpha-amino acid zwitterion creation_date: 2012-11-08T17:39:50Z [Term] id: GO:1901606 name: alpha-amino acid catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of an alpha-amino acid." [GOC:TermGenie] synonym: "alpha-amino acid breakdown" EXACT [GOC:TermGenie] synonym: "alpha-amino acid catabolism" EXACT [GOC:TermGenie] synonym: "alpha-amino acid degradation" EXACT [GOC:TermGenie] is_a: GO:1901575 ! organic substance catabolic process is_a: GO:1901605 ! alpha-amino acid metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:78608 ! has primary input alpha-amino acid zwitterion relationship: RO:0004009 CHEBI:78608 ! has primary input alpha-amino acid zwitterion creation_date: 2012-11-08T17:39:54Z [Term] id: GO:1901607 name: alpha-amino acid biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of an alpha-amino acid." [GOC:TermGenie] synonym: "alpha-amino acid anabolism" EXACT [GOC:TermGenie] synonym: "alpha-amino acid biosynthesis" EXACT [GOC:TermGenie] synonym: "alpha-amino acid formation" EXACT [GOC:TermGenie] synonym: "alpha-amino acid synthesis" EXACT [GOC:TermGenie] is_a: GO:1901576 ! organic substance biosynthetic process is_a: GO:1901605 ! alpha-amino acid metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:78608 ! has primary output alpha-amino acid zwitterion relationship: RO:0004008 CHEBI:78608 ! has primary output alpha-amino acid zwitterion creation_date: 2012-11-08T17:39:58Z [Term] id: GO:1901608 name: regulation of vesicle transport along microtubule namespace: biological_process def: "Any process that modulates the frequency, rate or extent of vesicle transport along microtubule." [GOC:TermGenie] synonym: "regulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] is_a: GO:1902513 ! regulation of organelle transport along microtubule intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0047496 ! regulates (processual) vesicle transport along microtubule relationship: RO:0002211 GO:0047496 ! regulates (processual) vesicle transport along microtubule creation_date: 2012-11-08T21:49:44Z [Term] id: GO:1901609 name: negative regulation of vesicle transport along microtubule namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of vesicle transport along microtubule." [GOC:TermGenie] synonym: "down regulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] synonym: "down regulation of vesicle transport along microtubule" EXACT [GOC:TermGenie] synonym: "down-regulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] synonym: "down-regulation of vesicle transport along microtubule" EXACT [GOC:TermGenie] synonym: "downregulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] synonym: "downregulation of vesicle transport along microtubule" EXACT [GOC:TermGenie] synonym: "inhibition of microtubule-based vesicle localization" EXACT [GOC:TermGenie] synonym: "negative regulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] is_a: GO:0032387 ! negative regulation of intracellular transport is_a: GO:1901608 ! regulation of vesicle transport along microtubule intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0047496 ! negatively regulates vesicle transport along microtubule relationship: RO:0002212 GO:0047496 ! negatively regulates vesicle transport along microtubule creation_date: 2012-11-08T21:49:48Z [Term] id: GO:1901610 name: positive regulation of vesicle transport along microtubule namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of vesicle transport along microtubule." [GOC:TermGenie] synonym: "activation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] synonym: "positive regulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] synonym: "up regulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] synonym: "up regulation of vesicle transport along microtubule" EXACT [GOC:TermGenie] synonym: "up-regulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] synonym: "up-regulation of vesicle transport along microtubule" EXACT [GOC:TermGenie] synonym: "upregulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] synonym: "upregulation of vesicle transport along microtubule" EXACT [GOC:TermGenie] is_a: GO:0032388 ! positive regulation of intracellular transport is_a: GO:1901608 ! regulation of vesicle transport along microtubule intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0047496 ! positively regulates vesicle transport along microtubule relationship: RO:0002213 GO:0047496 ! positively regulates vesicle transport along microtubule creation_date: 2012-11-08T21:49:53Z [Term] id: GO:1901615 name: organic hydroxy compound metabolic process namespace: biological_process def: "The chemical reactions and pathways involving organic hydroxy compound." [GOC:pr, GOC:TermGenie] synonym: "organic hydroxy compound metabolism" EXACT [GOC:TermGenie] is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:33822 ! has primary input or output organic hydroxy compound relationship: RO:0004007 CHEBI:33822 ! has primary input or output organic hydroxy compound creation_date: 2012-11-13T12:54:27Z [Term] id: GO:1901616 name: organic hydroxy compound catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of organic hydroxy compound." [GOC:pr, GOC:TermGenie] synonym: "organic hydroxy compound breakdown" EXACT [GOC:TermGenie] synonym: "organic hydroxy compound catabolism" EXACT [GOC:TermGenie] synonym: "organic hydroxy compound degradation" EXACT [GOC:TermGenie] is_a: GO:1901575 ! organic substance catabolic process is_a: GO:1901615 ! organic hydroxy compound metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:33822 ! has primary input organic hydroxy compound relationship: RO:0004009 CHEBI:33822 ! has primary input organic hydroxy compound creation_date: 2012-11-13T12:54:31Z [Term] id: GO:1901617 name: organic hydroxy compound biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of organic hydroxy compound." [GOC:pr, GOC:TermGenie] synonym: "organic hydroxy compound anabolism" EXACT [GOC:TermGenie] synonym: "organic hydroxy compound biosynthesis" EXACT [GOC:TermGenie] synonym: "organic hydroxy compound formation" EXACT [GOC:TermGenie] synonym: "organic hydroxy compound synthesis" EXACT [GOC:TermGenie] is_a: GO:1901576 ! organic substance biosynthetic process is_a: GO:1901615 ! organic hydroxy compound metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:33822 ! has primary output organic hydroxy compound relationship: RO:0004008 CHEBI:33822 ! has primary output organic hydroxy compound creation_date: 2012-11-13T12:54:36Z [Term] id: GO:1901618 name: organic hydroxy compound transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of organic hydroxy compound from one side of a membrane to the other." [GOC:pr, GOC:TermGenie] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:33822 ! has primary input organic hydroxy compound relationship: RO:0004009 CHEBI:33822 ! has primary input organic hydroxy compound creation_date: 2012-11-13T12:59:01Z [Term] id: GO:1901652 name: response to peptide namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus." [GOC:pr, GOC:TermGenie] is_a: GO:0010243 ! response to organonitrogen compound is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:16670 ! has primary input peptide relationship: RO:0004009 CHEBI:16670 ! has primary input peptide creation_date: 2012-11-20T09:45:15Z [Term] id: GO:1901654 name: response to ketone namespace: biological_process def: "A response that results in a state of tolerance to ketone." [GOC:mengo_curators, PMID:23356676] is_a: GO:0010033 ! response to organic substance is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:17087 ! has primary input ketone relationship: RO:0004009 CHEBI:17087 ! has primary input ketone creation_date: 2012-11-20T10:55:47Z [Term] id: GO:1901682 name: sulfur compound transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of a sulfur compound from one side of a membrane to the other." [GOC:pr, GOC:TermGenie] synonym: "sulfur molecular entity transmembrane transporter activity" EXACT [] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:26835 ! has primary input sulfur molecular entity relationship: RO:0004009 CHEBI:26835 ! has primary input sulfur molecular entity creation_date: 2012-11-26T20:45:29Z [Term] id: GO:1901692 name: regulation of compound eye retinal cell apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of compound eye retinal cell apoptotic process." [GOC:mtg_apoptosis, GOC:TermGenie, PMID:12021768] is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1990010 ! regulates (processual) compound eye retinal cell apoptotic process relationship: RO:0002211 GO:1990010 ! regulates (processual) compound eye retinal cell apoptotic process creation_date: 2012-12-12T10:28:35Z [Term] id: GO:1901693 name: negative regulation of compound eye retinal cell apoptotic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of compound eye retinal cell apoptotic process." [GOC:mtg_apoptosis, GOC:TermGenie, PMID:12021768] synonym: "down regulation of compound eye retinal cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of compound eye retinal cell apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of compound eye retinal cell apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0043066 ! negative regulation of apoptotic process is_a: GO:1901692 ! regulation of compound eye retinal cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1990010 ! negatively regulates compound eye retinal cell apoptotic process relationship: RO:0002212 GO:1990010 ! negatively regulates compound eye retinal cell apoptotic process creation_date: 2012-12-12T10:28:40Z [Term] id: GO:1901694 name: positive regulation of compound eye retinal cell apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of compound eye retinal cell apoptotic process." [GOC:mtg_apoptosis, GOC:TermGenie, PMID:12021768] synonym: "up regulation of compound eye retinal cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of compound eye retinal cell apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of compound eye retinal cell apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0043065 ! positive regulation of apoptotic process is_a: GO:0046672 ! positive regulation of compound eye retinal cell programmed cell death is_a: GO:1901692 ! regulation of compound eye retinal cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1990010 ! positively regulates compound eye retinal cell apoptotic process relationship: RO:0002213 GO:1990010 ! positively regulates compound eye retinal cell apoptotic process creation_date: 2012-12-12T10:28:45Z [Term] id: GO:1901698 name: response to nitrogen compound namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus." [GOC:pr, GOC:TermGenie] synonym: "response to nitrogen molecular entity" EXACT [] is_a: GO:0042221 ! response to chemical intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:51143 ! has primary input nitrogen molecular entity relationship: RO:0004009 CHEBI:51143 ! has primary input nitrogen molecular entity creation_date: 2012-12-13T15:06:08Z [Term] id: GO:1901700 name: response to oxygen-containing compound namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus." [GOC:pr, GOC:TermGenie] synonym: "response to oxygen molecular entity" EXACT [] is_a: GO:0042221 ! response to chemical intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:25806 ! has primary input oxygen molecular entity relationship: RO:0004009 CHEBI:25806 ! has primary input oxygen molecular entity creation_date: 2012-12-13T15:11:37Z [Term] id: GO:1901702 name: salt transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of salt from one side of a membrane to the other." [GOC:pr, GOC:TermGenie] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:24866 ! has primary input salt relationship: RO:0004009 CHEBI:24866 ! has primary input salt creation_date: 2012-12-13T15:14:47Z [Term] id: GO:1901706 name: mesenchymal cell differentiation involved in bone development namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of bone as it progresses from its formation to the mature state." [GOC:hjd, GOC:TermGenie, PMID:21571217] is_a: GO:0048762 ! mesenchymal cell differentiation intersection_of: GO:0048762 ! mesenchymal cell differentiation intersection_of: BFO:0000050 GO:0060348 ! part of bone development relationship: BFO:0000050 GO:0060348 ! part of bone development creation_date: 2012-12-14T16:04:16Z [Term] id: GO:1901722 name: regulation of cell proliferation involved in kidney development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell proliferation involved in kidney development." [GOC:TermGenie, PMID:18182616] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0072111 ! regulates (processual) cell proliferation involved in kidney development relationship: RO:0002211 GO:0072111 ! regulates (processual) cell proliferation involved in kidney development creation_date: 2012-12-27T19:30:31Z [Term] id: GO:1901723 name: negative regulation of cell proliferation involved in kidney development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in kidney development." [GOC:TermGenie, PMID:18182616] synonym: "down regulation of cell proliferation involved in kidney development" EXACT [GOC:TermGenie] synonym: "down-regulation of cell proliferation involved in kidney development" EXACT [GOC:TermGenie] synonym: "downregulation of cell proliferation involved in kidney development" EXACT [GOC:TermGenie] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:1901722 ! regulation of cell proliferation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0072111 ! negatively regulates cell proliferation involved in kidney development relationship: RO:0002212 GO:0072111 ! negatively regulates cell proliferation involved in kidney development creation_date: 2012-12-27T19:30:35Z [Term] id: GO:1901724 name: positive regulation of cell proliferation involved in kidney development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell proliferation involved in kidney development." [GOC:TermGenie, PMID:18182616] synonym: "up regulation of cell proliferation involved in kidney development" EXACT [GOC:TermGenie] synonym: "up-regulation of cell proliferation involved in kidney development" EXACT [GOC:TermGenie] synonym: "upregulation of cell proliferation involved in kidney development" EXACT [GOC:TermGenie] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:1901722 ! regulation of cell proliferation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0072111 ! positively regulates cell proliferation involved in kidney development relationship: RO:0002213 GO:0072111 ! positively regulates cell proliferation involved in kidney development creation_date: 2012-12-27T19:30:40Z [Term] id: GO:1901861 name: regulation of muscle tissue development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of muscle tissue development." [GOC:TermGenie, GOC:yaf, PMID:23150719] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060537 ! regulates (processual) muscle tissue development relationship: RO:0002211 GO:0060537 ! regulates (processual) muscle tissue development creation_date: 2013-02-01T10:30:47Z [Term] id: GO:1901862 name: negative regulation of muscle tissue development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of muscle tissue development." [GOC:TermGenie, GOC:yaf, PMID:23150719] synonym: "down regulation of muscle tissue development" EXACT [GOC:TermGenie] synonym: "down-regulation of muscle tissue development" EXACT [GOC:TermGenie] synonym: "downregulation of muscle tissue development" EXACT [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:1901861 ! regulation of muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060537 ! negatively regulates muscle tissue development relationship: RO:0002212 GO:0060537 ! negatively regulates muscle tissue development creation_date: 2013-02-01T10:30:52Z [Term] id: GO:1901863 name: positive regulation of muscle tissue development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of muscle tissue development." [GOC:TermGenie, GOC:yaf, PMID:23150719] synonym: "up regulation of muscle tissue development" EXACT [GOC:TermGenie] synonym: "up-regulation of muscle tissue development" EXACT [GOC:TermGenie] synonym: "upregulation of muscle tissue development" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:1901861 ! regulation of muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060537 ! positively regulates muscle tissue development relationship: RO:0002213 GO:0060537 ! positively regulates muscle tissue development creation_date: 2013-02-01T10:30:57Z [Term] id: GO:1901879 name: regulation of protein depolymerization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein depolymerization." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:12032137] synonym: "regulation of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "regulation of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "regulation of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "regulation of protein polymer degradation" EXACT [GOC:TermGenie] is_a: GO:0043244 ! regulation of protein-containing complex disassembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0051261 ! regulates (processual) protein depolymerization relationship: RO:0002211 GO:0051261 ! regulates (processual) protein depolymerization creation_date: 2013-02-06T13:57:23Z [Term] id: GO:1901880 name: negative regulation of protein depolymerization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein depolymerization." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:12032137] synonym: "down regulation of protein depolymerization" EXACT [GOC:TermGenie] synonym: "down regulation of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "down regulation of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "down regulation of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "down regulation of protein polymer degradation" EXACT [GOC:TermGenie] synonym: "down-regulation of protein depolymerization" EXACT [GOC:TermGenie] synonym: "down-regulation of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "down-regulation of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "down-regulation of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of protein polymer degradation" EXACT [GOC:TermGenie] synonym: "downregulation of protein depolymerization" EXACT [GOC:TermGenie] synonym: "downregulation of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "downregulation of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "downregulation of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "downregulation of protein polymer degradation" EXACT [GOC:TermGenie] synonym: "inhibition of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "inhibition of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "inhibition of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "inhibition of protein polymer degradation" EXACT [GOC:TermGenie] synonym: "negative regulation of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "negative regulation of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "negative regulation of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of protein polymer degradation" EXACT [GOC:TermGenie] is_a: GO:0043242 ! negative regulation of protein-containing complex disassembly is_a: GO:1901879 ! regulation of protein depolymerization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0051261 ! negatively regulates protein depolymerization relationship: RO:0002212 GO:0051261 ! negatively regulates protein depolymerization creation_date: 2013-02-06T13:57:28Z [Term] id: GO:1901881 name: positive regulation of protein depolymerization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein depolymerization." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:12032137] synonym: "activation of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "activation of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "activation of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "activation of protein polymer degradation" EXACT [GOC:TermGenie] synonym: "positive regulation of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "positive regulation of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "positive regulation of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of protein polymer degradation" EXACT [GOC:TermGenie] synonym: "up regulation of protein depolymerization" EXACT [GOC:TermGenie] synonym: "up regulation of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "up regulation of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "up regulation of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "up regulation of protein polymer degradation" EXACT [GOC:TermGenie] synonym: "up-regulation of protein depolymerization" EXACT [GOC:TermGenie] synonym: "up-regulation of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "up-regulation of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "up-regulation of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of protein polymer degradation" EXACT [GOC:TermGenie] synonym: "upregulation of protein depolymerization" EXACT [GOC:TermGenie] synonym: "upregulation of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "upregulation of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "upregulation of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "upregulation of protein polymer degradation" EXACT [GOC:TermGenie] is_a: GO:0043243 ! positive regulation of protein-containing complex disassembly is_a: GO:1901879 ! regulation of protein depolymerization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0051261 ! positively regulates protein depolymerization relationship: RO:0002213 GO:0051261 ! positively regulates protein depolymerization creation_date: 2013-02-06T13:57:32Z [Term] id: GO:1901888 name: regulation of cell junction assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell junction assembly." [GOC:TermGenie] is_a: GO:0044087 ! regulation of cellular component biogenesis is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0034329 ! regulates (processual) cell junction assembly relationship: RO:0002211 GO:0034329 ! regulates (processual) cell junction assembly creation_date: 2013-02-06T19:40:32Z [Term] id: GO:1901889 name: negative regulation of cell junction assembly namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell junction assembly." [GOC:TermGenie] synonym: "down regulation of cell junction assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of cell junction assembly" EXACT [GOC:TermGenie] synonym: "downregulation of cell junction assembly" EXACT [GOC:TermGenie] is_a: GO:0051129 ! negative regulation of cellular component organization is_a: GO:1901888 ! regulation of cell junction assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0034329 ! negatively regulates cell junction assembly relationship: RO:0002212 GO:0034329 ! negatively regulates cell junction assembly creation_date: 2013-02-06T19:40:41Z [Term] id: GO:1901890 name: positive regulation of cell junction assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell junction assembly." [GOC:TermGenie] synonym: "up regulation of cell junction assembly" EXACT [GOC:TermGenie] synonym: "up-regulation of cell junction assembly" EXACT [GOC:TermGenie] synonym: "upregulation of cell junction assembly" EXACT [GOC:TermGenie] is_a: GO:0044089 ! positive regulation of cellular component biogenesis is_a: GO:0051130 ! positive regulation of cellular component organization is_a: GO:1901888 ! regulation of cell junction assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0034329 ! positively regulates cell junction assembly relationship: RO:0002213 GO:0034329 ! positively regulates cell junction assembly creation_date: 2013-02-06T19:40:46Z [Term] id: GO:1901963 name: regulation of cell proliferation involved in outflow tract morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis." [GOC:dph, GOC:mtg_heart, GOC:TermGenie, PMID:21419760] is_a: GO:2000136 ! regulation of cell proliferation involved in heart morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0061325 ! regulates (processual) cell proliferation involved in outflow tract morphogenesis relationship: RO:0002211 GO:0061325 ! regulates (processual) cell proliferation involved in outflow tract morphogenesis creation_date: 2013-02-20T20:30:26Z [Term] id: GO:1901964 name: positive regulation of cell proliferation involved in outflow tract morphogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis." [GOC:dph, GOC:mtg_heart, GOC:TermGenie, PMID:21419760] synonym: "up regulation of cell proliferation involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of cell proliferation involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of cell proliferation involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] is_a: GO:1901963 ! regulation of cell proliferation involved in outflow tract morphogenesis is_a: GO:2000138 ! positive regulation of cell proliferation involved in heart morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0061325 ! positively regulates cell proliferation involved in outflow tract morphogenesis relationship: RO:0002213 GO:0061325 ! positively regulates cell proliferation involved in outflow tract morphogenesis creation_date: 2013-02-20T20:30:31Z [Term] id: GO:1902017 name: regulation of cilium assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cilium assembly." [GOC:cilia, GOC:dph, GOC:TermGenie, PMID:17719545] synonym: "regulation of ciliogenesis" EXACT [GOC:TermGenie] is_a: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly is_a: GO:1902115 ! regulation of organelle assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060271 ! regulates (processual) cilium assembly relationship: RO:0002211 GO:0060271 ! regulates (processual) cilium assembly creation_date: 2013-03-26T18:10:51Z [Term] id: GO:1902018 name: negative regulation of cilium assembly namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cilium assembly." [GOC:cilia, GOC:dph, GOC:TermGenie, PMID:17719545] synonym: "down regulation of ciliogenesis" EXACT [GOC:TermGenie] synonym: "down regulation of cilium assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of ciliogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of cilium assembly" EXACT [GOC:TermGenie] synonym: "downregulation of ciliogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of cilium assembly" EXACT [GOC:TermGenie] synonym: "inhibition of ciliogenesis" EXACT [GOC:TermGenie] synonym: "negative regulation of ciliogenesis" EXACT [GOC:TermGenie] is_a: GO:0120033 ! negative regulation of plasma membrane bounded cell projection assembly is_a: GO:1902017 ! regulation of cilium assembly is_a: GO:1902116 ! negative regulation of organelle assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060271 ! negatively regulates cilium assembly relationship: RO:0002212 GO:0060271 ! negatively regulates cilium assembly creation_date: 2013-03-26T18:10:56Z [Term] id: GO:1902019 name: regulation of cilium-dependent cell motility namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cilium-dependent cell motility." [GOC:cilia, GOC:jl, GOC:TermGenie] synonym: "regulation of cilium cell motility" EXACT [] is_a: GO:2000145 ! regulation of cell motility intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060285 ! regulates (processual) cilium-dependent cell motility relationship: RO:0002211 GO:0060285 ! regulates (processual) cilium-dependent cell motility creation_date: 2013-03-27T14:42:38Z [Term] id: GO:1902020 name: negative regulation of cilium-dependent cell motility namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cilium-dependent cell motility." [GOC:cilia, GOC:jl, GOC:TermGenie] synonym: "down regulation of ciliary cell motility" EXACT [GOC:TermGenie] synonym: "down-regulation of ciliary cell motility" EXACT [GOC:TermGenie] synonym: "downregulation of ciliary cell motility" EXACT [GOC:TermGenie] synonym: "negative regulation of cilium cell motility" EXACT [] is_a: GO:1902019 ! regulation of cilium-dependent cell motility is_a: GO:2000146 ! negative regulation of cell motility intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060285 ! negatively regulates cilium-dependent cell motility relationship: RO:0002212 GO:0060285 ! negatively regulates cilium-dependent cell motility creation_date: 2013-03-27T14:42:42Z [Term] id: GO:1902033 name: regulation of hematopoietic stem cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of hematopoietic stem cell proliferation." [GOC:TermGenie, PMID:23403623] synonym: "regulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0072091 ! regulation of stem cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0071425 ! regulates (processual) hematopoietic stem cell proliferation relationship: RO:0002211 GO:0071425 ! regulates (processual) hematopoietic stem cell proliferation creation_date: 2013-04-02T05:13:19Z [Term] id: GO:1902034 name: negative regulation of hematopoietic stem cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell proliferation." [GOC:TermGenie, PMID:23403623] synonym: "down regulation of hematopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "down regulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of hematopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of hematopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "negative regulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] is_a: GO:1902033 ! regulation of hematopoietic stem cell proliferation is_a: GO:1903707 ! negative regulation of hemopoiesis is_a: GO:2000647 ! negative regulation of stem cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0071425 ! negatively regulates hematopoietic stem cell proliferation relationship: RO:0002212 GO:0071425 ! negatively regulates hematopoietic stem cell proliferation creation_date: 2013-04-02T05:13:24Z [Term] id: GO:1902035 name: positive regulation of hematopoietic stem cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell proliferation." [GOC:TermGenie, PMID:23403623] synonym: "positive regulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of hematopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of hematopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of hematopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] is_a: GO:1902033 ! regulation of hematopoietic stem cell proliferation is_a: GO:2000648 ! positive regulation of stem cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0071425 ! positively regulates hematopoietic stem cell proliferation relationship: RO:0002213 GO:0071425 ! positively regulates hematopoietic stem cell proliferation creation_date: 2013-04-02T05:13:31Z [Term] id: GO:1902036 name: regulation of hematopoietic stem cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of hematopoietic stem cell differentiation." [GOC:TermGenie, PMID:23403623] synonym: "regulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "regulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "regulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] is_a: GO:1901532 ! regulation of hematopoietic progenitor cell differentiation is_a: GO:2000736 ! regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060218 ! regulates (processual) hematopoietic stem cell differentiation relationship: RO:0002211 GO:0060218 ! regulates (processual) hematopoietic stem cell differentiation creation_date: 2013-04-02T05:19:09Z [Term] id: GO:1902037 name: negative regulation of hematopoietic stem cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell differentiation." [GOC:TermGenie, PMID:23403623] synonym: "down regulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of hematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of hematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of hematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "negative regulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "negative regulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "negative regulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] is_a: GO:1901533 ! negative regulation of hematopoietic progenitor cell differentiation is_a: GO:1902036 ! regulation of hematopoietic stem cell differentiation is_a: GO:2000737 ! negative regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060218 ! negatively regulates hematopoietic stem cell differentiation relationship: RO:0002212 GO:0060218 ! negatively regulates hematopoietic stem cell differentiation creation_date: 2013-04-02T05:19:14Z [Term] id: GO:1902038 name: positive regulation of hematopoietic stem cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell differentiation." [GOC:TermGenie, PMID:23403623] synonym: "positive regulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "positive regulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "positive regulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of hematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of hematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of hematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] is_a: GO:1901534 ! positive regulation of hematopoietic progenitor cell differentiation is_a: GO:1902036 ! regulation of hematopoietic stem cell differentiation is_a: GO:2000738 ! positive regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060218 ! positively regulates hematopoietic stem cell differentiation relationship: RO:0002213 GO:0060218 ! positively regulates hematopoietic stem cell differentiation creation_date: 2013-04-02T05:19:19Z [Term] id: GO:1902074 name: response to salt namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus." [GOC:mls, GOC:TermGenie, PMID:16666921] is_a: GO:0042221 ! response to chemical intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:24866 ! has primary input salt relationship: RO:0004009 CHEBI:24866 ! has primary input salt creation_date: 2013-04-22T15:41:57Z [Term] id: GO:1902093 name: positive regulation of flagellated sperm motility namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of flagellated sperm motility." [GOC:cilia, GOC:jh2, GOC:krc, GOC:TermGenie, PMID:7513657] is_a: GO:0003353 ! positive regulation of cilium movement is_a: GO:1901317 ! regulation of flagellated sperm motility is_a: GO:2000155 ! positive regulation of cilium-dependent cell motility is_a: GO:2000243 ! positive regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030317 ! positively regulates flagellated sperm motility relationship: RO:0002213 GO:0030317 ! positively regulates flagellated sperm motility creation_date: 2013-04-29T09:15:25Z [Term] id: GO:1902105 name: regulation of leukocyte differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of leukocyte differentiation." [GOC:add, GOC:TermGenie] synonym: "regulation of immune cell differentiation" EXACT [GOC:TermGenie] synonym: "regulation of leucocyte differentiation" EXACT [GOC:TermGenie] is_a: GO:1903706 ! regulation of hemopoiesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002521 ! regulates (processual) leukocyte differentiation relationship: RO:0002211 GO:0002521 ! regulates (processual) leukocyte differentiation creation_date: 2013-05-02T17:32:42Z [Term] id: GO:1902106 name: negative regulation of leukocyte differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte differentiation." [GOC:add, GOC:TermGenie] synonym: "down regulation of immune cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of leucocyte differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of leukocyte differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of immune cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of leucocyte differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of leukocyte differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of immune cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of leucocyte differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of leukocyte differentiation" EXACT [GOC:TermGenie] synonym: "negative regulation of immune cell differentiation" EXACT [GOC:TermGenie] synonym: "negative regulation of leucocyte differentiation" EXACT [GOC:TermGenie] is_a: GO:1902105 ! regulation of leukocyte differentiation is_a: GO:1903707 ! negative regulation of hemopoiesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002521 ! negatively regulates leukocyte differentiation relationship: RO:0002212 GO:0002521 ! negatively regulates leukocyte differentiation creation_date: 2013-05-02T17:32:47Z [Term] id: GO:1902107 name: positive regulation of leukocyte differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of leukocyte differentiation." [GOC:add, GOC:TermGenie] synonym: "positive regulation of immune cell differentiation" EXACT [GOC:TermGenie] synonym: "positive regulation of leucocyte differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of immune cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of leucocyte differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of leukocyte differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of immune cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of leucocyte differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of leukocyte differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of immune cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of leucocyte differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of leukocyte differentiation" EXACT [GOC:TermGenie] is_a: GO:1902105 ! regulation of leukocyte differentiation is_a: GO:1903708 ! positive regulation of hemopoiesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002521 ! positively regulates leukocyte differentiation relationship: RO:0002213 GO:0002521 ! positively regulates leukocyte differentiation creation_date: 2013-05-02T17:32:52Z [Term] id: GO:1902115 name: regulation of organelle assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of organelle assembly." [GOC:pr, GOC:TermGenie] is_a: GO:0033043 ! regulation of organelle organization is_a: GO:0044087 ! regulation of cellular component biogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0070925 ! regulates (processual) organelle assembly relationship: RO:0002211 GO:0070925 ! regulates (processual) organelle assembly creation_date: 2013-05-14T09:43:21Z [Term] id: GO:1902116 name: negative regulation of organelle assembly namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of organelle assembly." [GOC:pr, GOC:TermGenie] synonym: "down regulation of organelle assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of organelle assembly" EXACT [GOC:TermGenie] synonym: "downregulation of organelle assembly" EXACT [GOC:TermGenie] is_a: GO:0010639 ! negative regulation of organelle organization is_a: GO:1902115 ! regulation of organelle assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0070925 ! negatively regulates organelle assembly relationship: RO:0002212 GO:0070925 ! negatively regulates organelle assembly creation_date: 2013-05-14T09:43:31Z [Term] id: GO:1902117 name: positive regulation of organelle assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of organelle assembly." [GOC:pr, GOC:TermGenie] synonym: "up regulation of organelle assembly" EXACT [GOC:TermGenie] synonym: "up-regulation of organelle assembly" EXACT [GOC:TermGenie] synonym: "upregulation of organelle assembly" EXACT [GOC:TermGenie] is_a: GO:0010638 ! positive regulation of organelle organization is_a: GO:0044089 ! positive regulation of cellular component biogenesis is_a: GO:1902115 ! regulation of organelle assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0070925 ! positively regulates organelle assembly relationship: RO:0002213 GO:0070925 ! positively regulates organelle assembly creation_date: 2013-05-14T09:43:36Z [Term] id: GO:1902217 name: erythrocyte apoptotic process namespace: biological_process def: "Any apoptotic process in an erythrocyte." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl, GOC:TermGenie, PMID:14569084] synonym: "RBC apoptotic process" EXACT [GOC:TermGenie] synonym: "red blood cell apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0033028 ! myeloid cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000232 ! occurs in erythrocyte relationship: BFO:0000066 CL:0000232 ! occurs in erythrocyte creation_date: 2013-06-13T10:02:29Z [Term] id: GO:1902250 name: regulation of erythrocyte apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of erythrocyte apoptotic process." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl, GOC:TermGenie, PMID:14569084] synonym: "regulation of RBC apoptotic process" EXACT [GOC:TermGenie] synonym: "regulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0033032 ! regulation of myeloid cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1902217 ! regulates (processual) erythrocyte apoptotic process relationship: RO:0002211 GO:1902217 ! regulates (processual) erythrocyte apoptotic process creation_date: 2013-06-20T19:30:53Z [Term] id: GO:1902251 name: negative regulation of erythrocyte apoptotic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of erythrocyte apoptotic process." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl, GOC:TermGenie, PMID:14569084] synonym: "down regulation of erythrocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "down regulation of RBC apoptotic process" EXACT [GOC:TermGenie] synonym: "down regulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of erythrocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of RBC apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of erythrocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of RBC apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] synonym: "negative regulation of RBC apoptotic process" EXACT [GOC:TermGenie] synonym: "negative regulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0033033 ! negative regulation of myeloid cell apoptotic process is_a: GO:1902250 ! regulation of erythrocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1902217 ! negatively regulates erythrocyte apoptotic process relationship: RO:0002212 GO:1902217 ! negatively regulates erythrocyte apoptotic process creation_date: 2013-06-20T19:30:59Z [Term] id: GO:1902252 name: positive regulation of erythrocyte apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of erythrocyte apoptotic process." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl, GOC:TermGenie, PMID:14569084] synonym: "positive regulation of RBC apoptotic process" EXACT [GOC:TermGenie] synonym: "positive regulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of erythrocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of RBC apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of erythrocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of RBC apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of erythrocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of RBC apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0033034 ! positive regulation of myeloid cell apoptotic process is_a: GO:1902250 ! regulation of erythrocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1902217 ! positively regulates erythrocyte apoptotic process relationship: RO:0002213 GO:1902217 ! positively regulates erythrocyte apoptotic process creation_date: 2013-06-20T19:31:04Z [Term] id: GO:1902256 name: regulation of apoptotic process involved in outflow tract morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis." [GOC:dph, GOC:mtg_apoptosis, GOC:TermGenie, PMID:16839542] is_a: GO:1902337 ! regulation of apoptotic process involved in morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003275 ! regulates (processual) apoptotic process involved in outflow tract morphogenesis relationship: RO:0002211 GO:0003275 ! regulates (processual) apoptotic process involved in outflow tract morphogenesis creation_date: 2013-06-24T19:12:24Z [Term] id: GO:1902257 name: negative regulation of apoptotic process involved in outflow tract morphogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis." [GOC:dph, GOC:mtg_apoptosis, GOC:TermGenie, PMID:16839542] synonym: "down regulation of apoptotic process involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic process involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic process involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] is_a: GO:1902256 ! regulation of apoptotic process involved in outflow tract morphogenesis is_a: GO:1902338 ! negative regulation of apoptotic process involved in morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0003275 ! negatively regulates apoptotic process involved in outflow tract morphogenesis relationship: RO:0002212 GO:0003275 ! negatively regulates apoptotic process involved in outflow tract morphogenesis creation_date: 2013-06-24T19:12:30Z [Term] id: GO:1902258 name: positive regulation of apoptotic process involved in outflow tract morphogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis." [GOC:dph, GOC:mtg_apoptosis, GOC:TermGenie, PMID:16839542] synonym: "up regulation of apoptotic process involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic process involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic process involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] is_a: GO:1902256 ! regulation of apoptotic process involved in outflow tract morphogenesis is_a: GO:1902339 ! positive regulation of apoptotic process involved in morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0003275 ! positively regulates apoptotic process involved in outflow tract morphogenesis relationship: RO:0002213 GO:0003275 ! positively regulates apoptotic process involved in outflow tract morphogenesis creation_date: 2013-06-24T19:12:42Z [Term] id: GO:1902262 name: apoptotic process involved in blood vessel morphogenesis namespace: biological_process def: "Any apoptotic process that is involved in blood vessel morphogenesis." [GOC:dph, GOC:mtg_apoptosis, GOC:TermGenie, PMID:16163358] synonym: "apoptotic cell death involved in patterning of blood vessels" EXACT [GOC:TermGenie] synonym: "apoptotic programmed cell death involved in patterning of blood vessels" EXACT [GOC:TermGenie] synonym: "programmed cell death by apoptosis involved in patterning of blood vessels" EXACT [GOC:TermGenie] is_a: GO:0060561 ! apoptotic process involved in morphogenesis intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000050 GO:0048514 ! part of blood vessel morphogenesis relationship: BFO:0000050 GO:0048514 ! part of blood vessel morphogenesis creation_date: 2013-06-25T16:16:00Z [Term] id: GO:1902275 name: regulation of chromatin organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of chromatin organization." [GO_REF:0000058, GOC:bf, GOC:TermGenie, GOC:vw, PMID:18314879] synonym: "regulation of chromatin organisation" EXACT [GOC:TermGenie] synonym: "regulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006325 ! regulates (processual) chromatin organization relationship: RO:0002211 GO:0006325 ! regulates (processual) chromatin organization creation_date: 2013-07-01T13:21:52Z [Term] id: GO:1902305 name: regulation of sodium ion transmembrane transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of sodium ion transmembrane transport." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:18591664] synonym: "regulation of sodium ion membrane transport" EXACT [GOC:TermGenie] is_a: GO:0002028 ! regulation of sodium ion transport is_a: GO:1904062 ! regulation of monoatomic cation transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0035725 ! regulates (processual) sodium ion transmembrane transport relationship: RO:0002211 GO:0035725 ! regulates (processual) sodium ion transmembrane transport creation_date: 2013-07-18T13:33:53Z [Term] id: GO:1902306 name: negative regulation of sodium ion transmembrane transport namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transport." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:18591664] synonym: "down regulation of sodium ion membrane transport" EXACT [GOC:TermGenie] synonym: "down regulation of sodium ion transmembrane transport" EXACT [GOC:TermGenie] synonym: "down-regulation of sodium ion membrane transport" EXACT [GOC:TermGenie] synonym: "down-regulation of sodium ion transmembrane transport" EXACT [GOC:TermGenie] synonym: "downregulation of sodium ion membrane transport" EXACT [GOC:TermGenie] synonym: "downregulation of sodium ion transmembrane transport" EXACT [GOC:TermGenie] synonym: "negative regulation of sodium ion membrane transport" EXACT [GOC:TermGenie] is_a: GO:0010766 ! negative regulation of sodium ion transport is_a: GO:1902305 ! regulation of sodium ion transmembrane transport is_a: GO:1904063 ! negative regulation of cation transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0035725 ! negatively regulates sodium ion transmembrane transport relationship: RO:0002212 GO:0035725 ! negatively regulates sodium ion transmembrane transport creation_date: 2013-07-18T13:34:01Z [Term] id: GO:1902307 name: positive regulation of sodium ion transmembrane transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transport." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:18591664] synonym: "positive regulation of sodium ion membrane transport" EXACT [GOC:TermGenie] synonym: "up regulation of sodium ion membrane transport" EXACT [GOC:TermGenie] synonym: "up regulation of sodium ion transmembrane transport" EXACT [GOC:TermGenie] synonym: "up-regulation of sodium ion membrane transport" EXACT [GOC:TermGenie] synonym: "up-regulation of sodium ion transmembrane transport" EXACT [GOC:TermGenie] synonym: "upregulation of sodium ion membrane transport" EXACT [GOC:TermGenie] synonym: "upregulation of sodium ion transmembrane transport" EXACT [GOC:TermGenie] is_a: GO:0010765 ! positive regulation of sodium ion transport is_a: GO:1902305 ! regulation of sodium ion transmembrane transport is_a: GO:1904064 ! positive regulation of cation transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0035725 ! positively regulates sodium ion transmembrane transport relationship: RO:0002213 GO:0035725 ! positively regulates sodium ion transmembrane transport creation_date: 2013-07-18T13:34:18Z [Term] id: GO:1902337 name: regulation of apoptotic process involved in morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of apoptotic process involved in morphogenesis." [GOC:sart, GOC:TermGenie, PMID:12202035] is_a: GO:1904748 ! regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060561 ! regulates (processual) apoptotic process involved in morphogenesis relationship: RO:0002211 GO:0060561 ! regulates (processual) apoptotic process involved in morphogenesis creation_date: 2013-07-29T15:03:16Z [Term] id: GO:1902338 name: negative regulation of apoptotic process involved in morphogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in morphogenesis." [GOC:sart, GOC:TermGenie, PMID:12202035] synonym: "down regulation of apoptotic process involved in morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic process involved in morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic process involved in morphogenesis" EXACT [GOC:TermGenie] is_a: GO:1902337 ! regulation of apoptotic process involved in morphogenesis is_a: GO:1904746 ! negative regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060561 ! negatively regulates apoptotic process involved in morphogenesis relationship: RO:0002212 GO:0060561 ! negatively regulates apoptotic process involved in morphogenesis creation_date: 2013-07-29T15:03:25Z [Term] id: GO:1902339 name: positive regulation of apoptotic process involved in morphogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in morphogenesis." [GOC:sart, GOC:TermGenie, PMID:12202035] synonym: "up regulation of apoptotic process involved in morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic process involved in morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic process involved in morphogenesis" EXACT [GOC:TermGenie] is_a: GO:1902337 ! regulation of apoptotic process involved in morphogenesis is_a: GO:1904747 ! positive regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060561 ! positively regulates apoptotic process involved in morphogenesis relationship: RO:0002213 GO:0060561 ! positively regulates apoptotic process involved in morphogenesis creation_date: 2013-07-29T15:03:33Z [Term] id: GO:1902340 name: negative regulation of chromosome condensation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of chromosome condensation." [GOC:TermGenie, PMID:23219725] synonym: "down regulation of chromosome condensation" EXACT [GOC:TermGenie] synonym: "down regulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie] synonym: "down regulation of nuclear chromosome condensation" EXACT [GOC:TermGenie] synonym: "down-regulation of chromosome condensation" EXACT [GOC:TermGenie] synonym: "down-regulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie] synonym: "down-regulation of nuclear chromosome condensation" EXACT [GOC:TermGenie] synonym: "downregulation of chromosome condensation" EXACT [GOC:TermGenie] synonym: "downregulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie] synonym: "downregulation of nuclear chromosome condensation" EXACT [GOC:TermGenie] synonym: "negative regulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie] synonym: "negative regulation of nuclear chromosome condensation" EXACT [GOC:TermGenie] is_a: GO:0060623 ! regulation of chromosome condensation is_a: GO:2001251 ! negative regulation of chromosome organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030261 ! negatively regulates chromosome condensation relationship: RO:0002212 GO:0030261 ! negatively regulates chromosome condensation creation_date: 2013-07-29T20:54:14Z [Term] id: GO:1902358 name: sulfate transmembrane transport namespace: biological_process def: "The directed movement of sulfate across a membrane." [GOC:dph, GOC:TermGenie, PMID:9055073] is_a: GO:0008272 ! sulfate transport is_a: GO:0098661 ! inorganic anion transmembrane transport intersection_of: GO:0055085 ! transmembrane transport intersection_of: RO:0004009 CHEBI:16189 ! has primary input sulfate creation_date: 2013-08-14T14:46:04Z [Term] id: GO:1902369 name: negative regulation of RNA catabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of RNA catabolic process." [GOC:bf, GOC:TermGenie, PMID:16640457] synonym: "down regulation of RNA breakdown" EXACT [GOC:TermGenie] synonym: "down regulation of RNA catabolic process" EXACT [GOC:TermGenie] synonym: "down regulation of RNA catabolism" EXACT [GOC:TermGenie] synonym: "down regulation of RNA degradation" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA breakdown" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA catabolic process" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA catabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA degradation" EXACT [GOC:TermGenie] synonym: "downregulation of RNA breakdown" EXACT [GOC:TermGenie] synonym: "downregulation of RNA catabolic process" EXACT [GOC:TermGenie] synonym: "downregulation of RNA catabolism" EXACT [GOC:TermGenie] synonym: "downregulation of RNA degradation" EXACT [GOC:TermGenie] synonym: "negative regulation of RNA breakdown" EXACT [GOC:TermGenie] synonym: "negative regulation of RNA catabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of RNA degradation" EXACT [GOC:TermGenie] is_a: GO:0031330 ! negative regulation of cellular catabolic process is_a: GO:0051253 ! negative regulation of RNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006401 ! negatively regulates RNA catabolic process relationship: RO:0002212 GO:0006401 ! negatively regulates RNA catabolic process creation_date: 2013-08-22T14:59:39Z [Term] id: GO:1902414 name: protein localization to cell junction namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within a cell junction." [GOC:TermGenie, PMID:18332111] synonym: "protein localisation in cell junction" EXACT [GOC:TermGenie] synonym: "protein localisation to cell junction" EXACT [GOC:TermGenie] synonym: "protein localization in cell junction" EXACT [GOC:TermGenie] is_a: GO:0008104 ! protein localization intersection_of: GO:0008104 ! protein localization intersection_of: RO:0002339 GO:0030054 ! has target end location cell junction relationship: RO:0002339 GO:0030054 ! has target end location cell junction creation_date: 2013-09-13T16:55:57Z [Term] id: GO:1902455 name: negative regulation of stem cell population maintenance namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of stem cell population maintenance." [GOC:hjd, GOC:TermGenie, PMID:22969033] synonym: "down regulation of stem cell maintenance" EXACT [GOC:TermGenie] synonym: "down-regulation of stem cell maintenance" EXACT [GOC:TermGenie] synonym: "downregulation of stem cell maintenance" EXACT [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:2000036 ! regulation of stem cell population maintenance intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0019827 ! negatively regulates stem cell population maintenance relationship: RO:0002212 GO:0019827 ! negatively regulates stem cell population maintenance creation_date: 2013-10-16T22:19:17Z [Term] id: GO:1902459 name: positive regulation of stem cell population maintenance namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of stem cell population maintenance." [GOC:hjd, GOC:TermGenie, PMID:22969033] synonym: "up regulation of stem cell maintenance" EXACT [GOC:TermGenie] synonym: "up-regulation of stem cell maintenance" EXACT [GOC:TermGenie] synonym: "upregulation of stem cell maintenance" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:2000036 ! regulation of stem cell population maintenance intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0019827 ! positively regulates stem cell population maintenance relationship: RO:0002213 GO:0019827 ! positively regulates stem cell population maintenance creation_date: 2013-10-16T22:27:47Z [Term] id: GO:1902463 name: protein localization to cell leading edge namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within a cell leading edge." [GOC:lb, GOC:TermGenie, PMID:21543326] synonym: "protein localisation in cell leading edge" EXACT [GOC:TermGenie] synonym: "protein localisation to cell leading edge" EXACT [GOC:TermGenie] synonym: "protein localization in cell leading edge" EXACT [GOC:TermGenie] is_a: GO:0008104 ! protein localization intersection_of: GO:0008104 ! protein localization intersection_of: RO:0002339 GO:0031252 ! has target end location cell leading edge relationship: RO:0002339 GO:0031252 ! has target end location cell leading edge creation_date: 2013-10-22T12:36:07Z [Term] id: GO:1902473 name: regulation of protein localization to synapse namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein localization to synapse." [GOC:kmv, GOC:TermGenie, PMID:22588719] synonym: "regulation of protein localisation to synapse" EXACT [GOC:TermGenie] is_a: GO:0032880 ! regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0035418 ! regulates (processual) protein localization to synapse relationship: RO:0002211 GO:0035418 ! regulates (processual) protein localization to synapse creation_date: 2013-10-25T15:09:09Z [Term] id: GO:1902474 name: positive regulation of protein localization to synapse namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein localization to synapse." [GOC:kmv, GOC:TermGenie, PMID:22588719] synonym: "positive regulation of protein localisation to synapse" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation to synapse" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization to synapse" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation to synapse" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to synapse" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation to synapse" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to synapse" EXACT [GOC:TermGenie] is_a: GO:1902473 ! regulation of protein localization to synapse is_a: GO:1903829 ! positive regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0035418 ! positively regulates protein localization to synapse relationship: RO:0002213 GO:0035418 ! positively regulates protein localization to synapse creation_date: 2013-10-25T15:09:18Z [Term] id: GO:1902484 name: Sertoli cell apoptotic process namespace: biological_process def: "Any apoptotic process in a Sertoli cell." [GOC:ic, GOC:TermGenie, PMID:17761895] is_a: GO:1904019 ! epithelial cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000216 ! occurs in Sertoli cell relationship: BFO:0000066 CL:0000216 ! occurs in Sertoli cell creation_date: 2013-11-06T11:27:34Z [Term] id: GO:1902488 name: cholangiocyte apoptotic process namespace: biological_process def: "Any apoptotic process in a cholangiocyte." [GOC:TermGenie, PMID:22961800] synonym: "epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] is_a: GO:1904019 ! epithelial cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:1000488 ! occurs in cholangiocyte relationship: BFO:0000066 CL:1000488 ! occurs in cholangiocyte creation_date: 2013-11-12T15:30:08Z [Term] id: GO:1902489 name: hepatoblast apoptotic process namespace: biological_process def: "Any apoptotic process in a hepatoblast." [GOC:TermGenie, PMID:22412967] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0005026 ! occurs in hepatoblast relationship: BFO:0000066 CL:0005026 ! occurs in hepatoblast creation_date: 2013-11-12T17:02:52Z [Term] id: GO:1902490 name: regulation of sperm capacitation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of sperm capacitation." [GOC:hjd, GOC:TermGenie, PMID:22539676] is_a: GO:0051239 ! regulation of multicellular organismal process is_a: GO:1903429 ! regulation of cell maturation is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048240 ! regulates (processual) sperm capacitation relationship: RO:0002211 GO:0048240 ! regulates (processual) sperm capacitation creation_date: 2013-11-12T21:17:03Z [Term] id: GO:1902491 name: negative regulation of sperm capacitation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of sperm capacitation." [GOC:hjd, GOC:TermGenie, PMID:22539676] synonym: "down regulation of sperm capacitation" EXACT [GOC:TermGenie] synonym: "down-regulation of sperm capacitation" EXACT [GOC:TermGenie] synonym: "downregulation of sperm capacitation" EXACT [GOC:TermGenie] is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1902490 ! regulation of sperm capacitation is_a: GO:1903430 ! negative regulation of cell maturation is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048240 ! negatively regulates sperm capacitation relationship: RO:0002212 GO:0048240 ! negatively regulates sperm capacitation creation_date: 2013-11-12T21:17:12Z [Term] id: GO:1902492 name: positive regulation of sperm capacitation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of sperm capacitation." [GOC:hjd, GOC:TermGenie, PMID:22539676] synonym: "up regulation of sperm capacitation" EXACT [GOC:TermGenie] synonym: "up-regulation of sperm capacitation" EXACT [GOC:TermGenie] synonym: "upregulation of sperm capacitation" EXACT [GOC:TermGenie] is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1902490 ! regulation of sperm capacitation is_a: GO:1903431 ! positive regulation of cell maturation is_a: GO:2000243 ! positive regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0048240 ! positively regulates sperm capacitation relationship: RO:0002213 GO:0048240 ! positively regulates sperm capacitation creation_date: 2013-11-12T21:17:21Z [Term] id: GO:1902494 name: catalytic complex namespace: cellular_component def: "A protein complex which is capable of catalytic activity." [GOC:bhm, GOC:TermGenie, PMID:8077207] synonym: "enzyme complex" EXACT [GOC:bhm, GOC:jl] is_a: GO:0032991 ! protein-containing complex intersection_of: GO:0032991 ! protein-containing complex intersection_of: RO:0002215 GO:0003824 ! capable of catalytic activity relationship: RO:0002215 GO:0003824 ! capable of catalytic activity creation_date: 2013-11-13T16:18:47Z [Term] id: GO:1902495 name: transmembrane transporter complex namespace: cellular_component def: "A transmembrane protein complex which enables the transfer of a substance from one side of a membrane to the other." [GOC:bhm, GOC:TermGenie, PMID:18024586] is_a: GO:0098796 ! membrane protein complex is_a: GO:1990351 ! transporter complex intersection_of: GO:0032991 ! protein-containing complex intersection_of: RO:0002215 GO:0022857 ! capable of transmembrane transporter activity relationship: RO:0002215 GO:0022857 ! capable of transmembrane transporter activity creation_date: 2013-11-13T16:23:04Z [Term] id: GO:1902510 name: regulation of apoptotic DNA fragmentation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of apoptotic DNA fragmentation." [GOC:hjd, GOC:TermGenie, PMID:15572351, PMID:15723341] synonym: "regulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie] synonym: "regulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie] synonym: "regulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie] synonym: "regulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie] is_a: GO:1903624 ! regulation of DNA catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006309 ! regulates (processual) apoptotic DNA fragmentation relationship: RO:0002211 GO:0006309 ! regulates (processual) apoptotic DNA fragmentation creation_date: 2013-11-15T18:28:32Z [Term] id: GO:1902511 name: negative regulation of apoptotic DNA fragmentation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic DNA fragmentation." [GOC:hjd, GOC:TermGenie, PMID:15572351] synonym: "down regulation of apoptotic DNA fragmentation" EXACT [GOC:TermGenie] synonym: "down regulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie] synonym: "down regulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie] synonym: "down regulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie] synonym: "down regulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic DNA fragmentation" EXACT [GOC:TermGenie] synonym: "down-regulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie] synonym: "down-regulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie] synonym: "down-regulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie] synonym: "down-regulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic DNA fragmentation" EXACT [GOC:TermGenie] synonym: "downregulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie] synonym: "downregulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie] synonym: "downregulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie] synonym: "downregulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie] synonym: "negative regulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie] synonym: "negative regulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie] synonym: "negative regulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie] synonym: "negative regulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie] is_a: GO:1902510 ! regulation of apoptotic DNA fragmentation is_a: GO:1903625 ! negative regulation of DNA catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006309 ! negatively regulates apoptotic DNA fragmentation relationship: RO:0002212 GO:0006309 ! negatively regulates apoptotic DNA fragmentation creation_date: 2013-11-15T18:28:41Z [Term] id: GO:1902512 name: positive regulation of apoptotic DNA fragmentation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of apoptotic DNA fragmentation." [GOC:hjd, GOC:TermGenie, PMID:15572351] synonym: "positive regulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie] synonym: "positive regulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie] synonym: "positive regulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie] synonym: "positive regulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic DNA fragmentation" EXACT [GOC:TermGenie] synonym: "up regulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie] synonym: "up regulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie] synonym: "up regulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie] synonym: "up regulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic DNA fragmentation" EXACT [GOC:TermGenie] synonym: "up-regulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie] synonym: "up-regulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie] synonym: "up-regulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie] synonym: "up-regulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic DNA fragmentation" EXACT [GOC:TermGenie] synonym: "upregulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie] synonym: "upregulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie] synonym: "upregulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie] synonym: "upregulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie] is_a: GO:1902510 ! regulation of apoptotic DNA fragmentation is_a: GO:1903626 ! positive regulation of DNA catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006309 ! positively regulates apoptotic DNA fragmentation relationship: RO:0002213 GO:0006309 ! positively regulates apoptotic DNA fragmentation creation_date: 2013-11-15T18:28:50Z [Term] id: GO:1902513 name: regulation of organelle transport along microtubule namespace: biological_process def: "Any process that modulates the frequency, rate or extent of organelle transport along microtubule." [GOC:dph, GOC:TermGenie, PMID:21147087] synonym: "regulation of microtubule-based organelle localization" EXACT [GOC:TermGenie] is_a: GO:0032386 ! regulation of intracellular transport is_a: GO:0060632 ! regulation of microtubule-based movement intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0072384 ! regulates (processual) organelle transport along microtubule relationship: RO:0002211 GO:0072384 ! regulates (processual) organelle transport along microtubule creation_date: 2013-11-15T20:15:17Z [Term] id: GO:1902531 name: regulation of intracellular signal transduction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of intracellular signal transduction." [GOC:dph, GOC:signaling, GOC:tb, GOC:TermGenie] synonym: "regulation of intracellular signaling cascade" EXACT [GOC:TermGenie] synonym: "regulation of intracellular signaling chain" EXACT [GOC:TermGenie] is_a: GO:0009966 ! regulation of signal transduction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0035556 ! regulates (processual) intracellular signal transduction relationship: RO:0002211 GO:0035556 ! regulates (processual) intracellular signal transduction creation_date: 2013-12-02T11:32:52Z [Term] id: GO:1902532 name: negative regulation of intracellular signal transduction namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction." [GOC:dph, GOC:signaling, GOC:tb, GOC:TermGenie] synonym: "down regulation of intracellular signal transduction" EXACT [GOC:TermGenie] synonym: "down regulation of intracellular signaling chain" EXACT [GOC:TermGenie] synonym: "down-regulation of intracellular signal transduction" EXACT [GOC:TermGenie] synonym: "down-regulation of intracellular signaling chain" EXACT [GOC:TermGenie] synonym: "downregulation of intracellular signal transduction" EXACT [GOC:TermGenie] synonym: "downregulation of intracellular signaling chain" EXACT [GOC:TermGenie] synonym: "negative regulation of intracellular protein kinase cascade" EXACT [] synonym: "negative regulation of intracellular signaling cascade" EXACT [GOC:TermGenie] synonym: "negative regulation of intracellular signaling chain" EXACT [GOC:TermGenie] is_a: GO:0009968 ! negative regulation of signal transduction is_a: GO:1902531 ! regulation of intracellular signal transduction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0035556 ! negatively regulates intracellular signal transduction relationship: RO:0002212 GO:0035556 ! negatively regulates intracellular signal transduction creation_date: 2013-12-02T11:33:01Z [Term] id: GO:1902533 name: positive regulation of intracellular signal transduction namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of intracellular signal transduction." [GOC:BHF, GOC:dph, GOC:signaling, GOC:tb, GOC:TermGenie] synonym: "positive regulation of intracellular signaling chain" EXACT [GOC:TermGenie] synonym: "up regulation of intracellular signal transduction" EXACT [GOC:TermGenie] synonym: "up regulation of intracellular signaling chain" EXACT [GOC:TermGenie] synonym: "up-regulation of intracellular signal transduction" EXACT [GOC:TermGenie] synonym: "up-regulation of intracellular signaling chain" EXACT [GOC:TermGenie] synonym: "upregulation of intracellular signal transduction" EXACT [GOC:TermGenie] synonym: "upregulation of intracellular signaling chain" EXACT [GOC:TermGenie] is_a: GO:0009967 ! positive regulation of signal transduction is_a: GO:1902531 ! regulation of intracellular signal transduction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0035556 ! positively regulates intracellular signal transduction relationship: RO:0002213 GO:0035556 ! positively regulates intracellular signal transduction creation_date: 2013-12-02T11:33:10Z [Term] id: GO:1902570 name: protein localization to nucleolus namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within a nucleolus." [GOC:TermGenie, PMID:22809626] synonym: "protein localisation in nucleolus" EXACT [GOC:TermGenie] synonym: "protein localisation to nucleolus" EXACT [GOC:TermGenie] synonym: "protein localization in nucleolus" EXACT [GOC:TermGenie] is_a: GO:0034504 ! protein localization to nucleus intersection_of: GO:0008104 ! protein localization intersection_of: RO:0002339 GO:0005730 ! has target end location nucleolus relationship: RO:0002339 GO:0005730 ! has target end location nucleolus creation_date: 2013-12-10T16:25:28Z [Term] id: GO:1902679 name: negative regulation of RNA biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of RNA biosynthetic process." [GO:jl, GO_REF:0000058, GOC:TermGenie] synonym: "down regulation of RNA anabolism" EXACT [GOC:TermGenie] synonym: "down regulation of RNA biosynthesis" EXACT [GOC:TermGenie] synonym: "down regulation of RNA biosynthetic process" EXACT [GOC:TermGenie] synonym: "down regulation of RNA formation" EXACT [GOC:TermGenie] synonym: "down regulation of RNA synthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA anabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA biosynthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA biosynthetic process" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA formation" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA synthesis" EXACT [GOC:TermGenie] synonym: "downregulation of RNA anabolism" EXACT [GOC:TermGenie] synonym: "downregulation of RNA biosynthesis" EXACT [GOC:TermGenie] synonym: "downregulation of RNA biosynthetic process" EXACT [GOC:TermGenie] synonym: "downregulation of RNA formation" EXACT [GOC:TermGenie] synonym: "downregulation of RNA synthesis" EXACT [GOC:TermGenie] synonym: "negative regulation of RNA anabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of RNA biosynthesis" EXACT [GOC:TermGenie] synonym: "negative regulation of RNA formation" EXACT [GOC:TermGenie] synonym: "negative regulation of RNA synthesis" EXACT [GOC:TermGenie] is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process is_a: GO:0051253 ! negative regulation of RNA metabolic process is_a: GO:2001141 ! regulation of RNA biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0032774 ! negatively regulates RNA biosynthetic process relationship: RO:0002212 GO:0032774 ! negatively regulates RNA biosynthetic process creation_date: 2014-02-05T16:32:01Z [Term] id: GO:1902680 name: positive regulation of RNA biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of RNA biosynthetic process." [GO:jl, GO_REF:0000058, GOC:TermGenie] synonym: "positive regulation of RNA anabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of RNA biosynthesis" EXACT [GOC:TermGenie] synonym: "positive regulation of RNA formation" EXACT [GOC:TermGenie] synonym: "positive regulation of RNA synthesis" EXACT [GOC:TermGenie] synonym: "up regulation of RNA anabolism" EXACT [GOC:TermGenie] synonym: "up regulation of RNA biosynthesis" EXACT [GOC:TermGenie] synonym: "up regulation of RNA biosynthetic process" EXACT [GOC:TermGenie] synonym: "up regulation of RNA formation" EXACT [GOC:TermGenie] synonym: "up regulation of RNA synthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of RNA anabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of RNA biosynthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of RNA biosynthetic process" EXACT [GOC:TermGenie] synonym: "up-regulation of RNA formation" EXACT [GOC:TermGenie] synonym: "up-regulation of RNA synthesis" EXACT [GOC:TermGenie] synonym: "upregulation of RNA anabolism" EXACT [GOC:TermGenie] synonym: "upregulation of RNA biosynthesis" EXACT [GOC:TermGenie] synonym: "upregulation of RNA biosynthetic process" EXACT [GOC:TermGenie] synonym: "upregulation of RNA formation" EXACT [GOC:TermGenie] synonym: "upregulation of RNA synthesis" EXACT [GOC:TermGenie] is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process is_a: GO:0051254 ! positive regulation of RNA metabolic process is_a: GO:2001141 ! regulation of RNA biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0032774 ! positively regulates RNA biosynthetic process relationship: RO:0002213 GO:0032774 ! positively regulates RNA biosynthetic process creation_date: 2014-02-05T16:32:10Z [Term] id: GO:1902692 name: regulation of neuroblast proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of neuroblast proliferation." [GO_REF:0000058, GOC:PARL, GOC:rl, GOC:TermGenie, PMID:21168496] is_a: GO:2000177 ! regulation of neural precursor cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007405 ! regulates (processual) neuroblast proliferation relationship: RO:0002211 GO:0007405 ! regulates (processual) neuroblast proliferation creation_date: 2014-02-18T10:03:31Z [Term] id: GO:1902738 name: regulation of chondrocyte differentiation involved in endochondral bone morphogenesis namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage." [GO_REF:0000058, GOC:TermGenie, PMID:8662546] is_a: GO:0032330 ! regulation of chondrocyte differentiation is_a: GO:1903010 ! regulation of bone development is_a: GO:2000027 ! regulation of animal organ morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003413 ! regulates (processual) chondrocyte differentiation involved in endochondral bone morphogenesis relationship: RO:0002211 GO:0003413 ! regulates (processual) chondrocyte differentiation involved in endochondral bone morphogenesis creation_date: 2014-02-26T15:36:15Z [Term] id: GO:1902742 name: apoptotic process involved in development namespace: biological_process def: "Any apoptotic process that is involved in anatomical structure development." [GO_REF:0000060, GOC:mtg_apoptosis, GOC:pg, GOC:TermGenie] synonym: "apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "apoptotic process involved in anatomical structure development" EXACT [] synonym: "apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000050 GO:0048856 ! part of anatomical structure development relationship: BFO:0000050 GO:0048856 ! part of anatomical structure development creation_date: 2014-02-28T13:09:43Z [Term] id: GO:1902761 name: positive regulation of chondrocyte development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of chondrocyte development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16575901] synonym: "up regulation of chondrocyte development" EXACT [GOC:TermGenie] synonym: "up-regulation of chondrocyte development" EXACT [GOC:TermGenie] synonym: "upregulation of chondrocyte development" EXACT [GOC:TermGenie] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0032332 ! positive regulation of chondrocyte differentiation is_a: GO:0061181 ! regulation of chondrocyte development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002063 ! positively regulates chondrocyte development relationship: RO:0002213 GO:0002063 ! positively regulates chondrocyte development creation_date: 2014-03-07T17:45:55Z [Term] id: GO:1902809 name: regulation of skeletal muscle fiber differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of skeletal muscle fiber differentiation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:17879321] is_a: GO:0010830 ! regulation of myotube differentiation is_a: GO:2001014 ! regulation of skeletal muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0098528 ! regulates (processual) skeletal muscle fiber differentiation relationship: RO:0002211 GO:0098528 ! regulates (processual) skeletal muscle fiber differentiation creation_date: 2014-03-26T21:18:26Z [Term] id: GO:1902810 name: negative regulation of skeletal muscle fiber differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle fiber differentiation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:17879321] synonym: "down regulation of skeletal muscle fiber differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of skeletal muscle fiber differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of skeletal muscle fiber differentiation" EXACT [GOC:TermGenie] is_a: GO:0010832 ! negative regulation of myotube differentiation is_a: GO:1902809 ! regulation of skeletal muscle fiber differentiation is_a: GO:2001015 ! negative regulation of skeletal muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0098528 ! negatively regulates skeletal muscle fiber differentiation relationship: RO:0002212 GO:0098528 ! negatively regulates skeletal muscle fiber differentiation creation_date: 2014-03-26T21:18:32Z [Term] id: GO:1902811 name: positive regulation of skeletal muscle fiber differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of skeletal muscle fiber differentiation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:17879321] synonym: "up regulation of skeletal muscle fiber differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of skeletal muscle fiber differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of skeletal muscle fiber differentiation" EXACT [GOC:TermGenie] is_a: GO:0010831 ! positive regulation of myotube differentiation is_a: GO:1902809 ! regulation of skeletal muscle fiber differentiation is_a: GO:2001016 ! positive regulation of skeletal muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0098528 ! positively regulates skeletal muscle fiber differentiation relationship: RO:0002213 GO:0098528 ! positively regulates skeletal muscle fiber differentiation creation_date: 2014-03-26T21:18:38Z [Term] id: GO:1902816 name: regulation of protein localization to microtubule namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein localization to microtubule." [GO_REF:0000058, GOC:TermGenie, GOC:vw, PMID:23087209] synonym: "regulation of protein localisation to microtubule" EXACT [GOC:TermGenie] is_a: GO:0032880 ! regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0035372 ! regulates (processual) protein localization to microtubule relationship: RO:0002211 GO:0035372 ! regulates (processual) protein localization to microtubule creation_date: 2014-03-27T22:07:12Z [Term] id: GO:1902817 name: negative regulation of protein localization to microtubule namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to microtubule." [GO_REF:0000058, GOC:TermGenie, GOC:vw, PMID:23087209] synonym: "down regulation of protein localisation to microtubule" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization to microtubule" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation to microtubule" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to microtubule" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation to microtubule" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to microtubule" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localisation to microtubule" EXACT [GOC:TermGenie] is_a: GO:1902816 ! regulation of protein localization to microtubule is_a: GO:1903828 ! negative regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0035372 ! negatively regulates protein localization to microtubule relationship: RO:0002212 GO:0035372 ! negatively regulates protein localization to microtubule creation_date: 2014-03-27T22:07:18Z [Term] id: GO:1902838 name: regulation of nuclear migration along microtubule namespace: biological_process def: "Any process that modulates the frequency, rate or extent of nuclear migration along microtubule." [GO_REF:0000058, GOC:TermGenie, PMID:23087209] synonym: "regulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "regulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "regulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "regulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "regulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] synonym: "regulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "regulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] synonym: "regulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] is_a: GO:1902513 ! regulation of organelle transport along microtubule intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030473 ! regulates (processual) nuclear migration along microtubule relationship: RO:0002211 GO:0030473 ! regulates (processual) nuclear migration along microtubule creation_date: 2014-04-01T13:50:23Z [Term] id: GO:1902839 name: negative regulation of nuclear migration along microtubule namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of nuclear migration along microtubule." [GO_REF:0000058, GOC:TermGenie, PMID:23087209] synonym: "down regulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "down regulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "down regulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "down regulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "down regulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] synonym: "down regulation of nuclear migration along microtubule" EXACT [GOC:TermGenie] synonym: "down regulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "down regulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] synonym: "down regulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "down-regulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "down-regulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "down-regulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "down-regulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "down-regulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] synonym: "down-regulation of nuclear migration along microtubule" EXACT [GOC:TermGenie] synonym: "down-regulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "down-regulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] synonym: "down-regulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "downregulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "downregulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "downregulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "downregulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "downregulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] synonym: "downregulation of nuclear migration along microtubule" EXACT [GOC:TermGenie] synonym: "downregulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "downregulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] synonym: "downregulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "negative regulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "negative regulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "negative regulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "negative regulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "negative regulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] synonym: "negative regulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "negative regulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] synonym: "negative regulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] is_a: GO:0032387 ! negative regulation of intracellular transport is_a: GO:1902838 ! regulation of nuclear migration along microtubule intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030473 ! negatively regulates nuclear migration along microtubule relationship: RO:0002212 GO:0030473 ! negatively regulates nuclear migration along microtubule creation_date: 2014-04-01T13:50:29Z [Term] id: GO:1902840 name: positive regulation of nuclear migration along microtubule namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of nuclear migration along microtubule." [GO_REF:0000058, GOC:TermGenie, PMID:23087209] synonym: "positive regulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "positive regulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "positive regulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "positive regulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "positive regulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] synonym: "positive regulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "positive regulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] synonym: "positive regulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "up regulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "up regulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "up regulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "up regulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "up regulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] synonym: "up regulation of nuclear migration along microtubule" EXACT [GOC:TermGenie] synonym: "up regulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "up regulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] synonym: "up regulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "up-regulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "up-regulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "up-regulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "up-regulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "up-regulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] synonym: "up-regulation of nuclear migration along microtubule" EXACT [GOC:TermGenie] synonym: "up-regulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "up-regulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] synonym: "up-regulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "upregulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "upregulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "upregulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "upregulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "upregulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] synonym: "upregulation of nuclear migration along microtubule" EXACT [GOC:TermGenie] synonym: "upregulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "upregulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] synonym: "upregulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] is_a: GO:0032388 ! positive regulation of intracellular transport is_a: GO:1902838 ! regulation of nuclear migration along microtubule intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030473 ! positively regulates nuclear migration along microtubule relationship: RO:0002213 GO:0030473 ! positively regulates nuclear migration along microtubule creation_date: 2014-04-01T13:50:35Z [Term] id: GO:1902850 name: microtubule cytoskeleton organization involved in mitosis namespace: biological_process def: "Any microtubule cytoskeleton organization that is involved in mitosis." [GO_REF:0000060, GOC:TermGenie, PMID:18799626] synonym: "microtubule cytoskeleton organisation involved in mitosis" EXACT [GOC:TermGenie] synonym: "microtubule dynamics involved in mitosis" EXACT [GOC:TermGenie] is_a: GO:0000226 ! microtubule cytoskeleton organization is_a: GO:1903047 ! mitotic cell cycle process intersection_of: GO:0000226 ! microtubule cytoskeleton organization intersection_of: BFO:0000050 GO:0000278 ! part of mitotic cell cycle creation_date: 2014-04-02T14:19:38Z [Term] id: GO:1902863 name: regulation of embryonic camera-type eye development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of embryonic camera-type eye development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] synonym: "regulation of embryonic eye development" EXACT [GOC:TermGenie] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0031076 ! regulates (processual) embryonic camera-type eye development relationship: RO:0002211 GO:0031076 ! regulates (processual) embryonic camera-type eye development creation_date: 2014-04-03T15:24:00Z [Term] id: GO:1902864 name: negative regulation of embryonic camera-type eye development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of embryonic camera-type eye development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] synonym: "down regulation of embryonic camera-type eye development" EXACT [GOC:TermGenie] synonym: "down regulation of embryonic eye development" EXACT [GOC:TermGenie] synonym: "down-regulation of embryonic camera-type eye development" EXACT [GOC:TermGenie] synonym: "down-regulation of embryonic eye development" EXACT [GOC:TermGenie] synonym: "downregulation of embryonic camera-type eye development" EXACT [GOC:TermGenie] synonym: "downregulation of embryonic eye development" EXACT [GOC:TermGenie] synonym: "negative regulation of embryonic eye development" EXACT [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:1902863 ! regulation of embryonic camera-type eye development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0031076 ! negatively regulates embryonic camera-type eye development relationship: RO:0002212 GO:0031076 ! negatively regulates embryonic camera-type eye development creation_date: 2014-04-03T15:24:06Z [Term] id: GO:1902865 name: positive regulation of embryonic camera-type eye development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of embryonic camera-type eye development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] synonym: "positive regulation of embryonic eye development" EXACT [GOC:TermGenie] synonym: "up regulation of embryonic camera-type eye development" EXACT [GOC:TermGenie] synonym: "up regulation of embryonic eye development" EXACT [GOC:TermGenie] synonym: "up-regulation of embryonic camera-type eye development" EXACT [GOC:TermGenie] synonym: "up-regulation of embryonic eye development" EXACT [GOC:TermGenie] synonym: "upregulation of embryonic camera-type eye development" EXACT [GOC:TermGenie] synonym: "upregulation of embryonic eye development" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:1902863 ! regulation of embryonic camera-type eye development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0031076 ! positively regulates embryonic camera-type eye development relationship: RO:0002213 GO:0031076 ! positively regulates embryonic camera-type eye development creation_date: 2014-04-03T15:24:12Z [Term] id: GO:1902866 name: regulation of retina development in camera-type eye namespace: biological_process def: "Any process that modulates the frequency, rate or extent of retina development in camera-type eye." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] synonym: "regulation of retina development in camera-style eye" EXACT [GOC:TermGenie] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060041 ! regulates (processual) retina development in camera-type eye relationship: RO:0002211 GO:0060041 ! regulates (processual) retina development in camera-type eye creation_date: 2014-04-03T15:24:17Z [Term] id: GO:1902867 name: negative regulation of retina development in camera-type eye namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of retina development in camera-type eye." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] synonym: "down regulation of retina development in camera-style eye" EXACT [GOC:TermGenie] synonym: "down regulation of retina development in camera-type eye" EXACT [GOC:TermGenie] synonym: "down-regulation of retina development in camera-style eye" EXACT [GOC:TermGenie] synonym: "down-regulation of retina development in camera-type eye" EXACT [GOC:TermGenie] synonym: "downregulation of retina development in camera-style eye" EXACT [GOC:TermGenie] synonym: "downregulation of retina development in camera-type eye" EXACT [GOC:TermGenie] synonym: "negative regulation of retina development in camera-style eye" EXACT [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1902866 ! regulation of retina development in camera-type eye intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060041 ! negatively regulates retina development in camera-type eye relationship: RO:0002212 GO:0060041 ! negatively regulates retina development in camera-type eye creation_date: 2014-04-03T15:24:23Z [Term] id: GO:1902868 name: positive regulation of retina development in camera-type eye namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of retina development in camera-type eye." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] synonym: "positive regulation of retina development in camera-style eye" EXACT [GOC:TermGenie] synonym: "up regulation of retina development in camera-style eye" EXACT [GOC:TermGenie] synonym: "up regulation of retina development in camera-type eye" EXACT [GOC:TermGenie] synonym: "up-regulation of retina development in camera-style eye" EXACT [GOC:TermGenie] synonym: "up-regulation of retina development in camera-type eye" EXACT [GOC:TermGenie] synonym: "upregulation of retina development in camera-style eye" EXACT [GOC:TermGenie] synonym: "upregulation of retina development in camera-type eye" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1902866 ! regulation of retina development in camera-type eye intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060041 ! positively regulates retina development in camera-type eye relationship: RO:0002213 GO:0060041 ! positively regulates retina development in camera-type eye creation_date: 2014-04-03T15:24:29Z [Term] id: GO:1902875 name: regulation of embryonic pattern specification namespace: biological_process def: "Any process that modulates the frequency, rate or extent of embryonic pattern specification." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0009880 ! regulates (processual) embryonic pattern specification relationship: RO:0002211 GO:0009880 ! regulates (processual) embryonic pattern specification creation_date: 2014-04-03T15:25:15Z [Term] id: GO:1902876 name: negative regulation of embryonic pattern specification namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of embryonic pattern specification." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] synonym: "down regulation of embryonic pattern specification" EXACT [GOC:TermGenie] synonym: "down-regulation of embryonic pattern specification" EXACT [GOC:TermGenie] synonym: "downregulation of embryonic pattern specification" EXACT [GOC:TermGenie] is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1902875 ! regulation of embryonic pattern specification intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0009880 ! negatively regulates embryonic pattern specification relationship: RO:0002212 GO:0009880 ! negatively regulates embryonic pattern specification creation_date: 2014-04-03T15:25:20Z [Term] id: GO:1902877 name: positive regulation of embryonic pattern specification namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of embryonic pattern specification." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] synonym: "up regulation of embryonic pattern specification" EXACT [GOC:TermGenie] synonym: "up-regulation of embryonic pattern specification" EXACT [GOC:TermGenie] synonym: "upregulation of embryonic pattern specification" EXACT [GOC:TermGenie] is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1902875 ! regulation of embryonic pattern specification intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0009880 ! positively regulates embryonic pattern specification relationship: RO:0002213 GO:0009880 ! positively regulates embryonic pattern specification creation_date: 2014-04-03T15:25:26Z [Term] id: GO:1902903 name: regulation of supramolecular fiber organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of supramolecular fiber organization." [GO_REF:0000058, GOC:PARL, GOC:rl, GOC:TermGenie, PMID:23921388] is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0097435 ! regulates (processual) supramolecular fiber organization relationship: RO:0002211 GO:0097435 ! regulates (processual) supramolecular fiber organization creation_date: 2014-04-15T16:46:36Z [Term] id: GO:1902904 name: negative regulation of supramolecular fiber organization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of fibril organization." [GO_REF:0000058, GOC:PARL, GOC:rl, GOC:TermGenie, PMID:23921388] is_a: GO:0051129 ! negative regulation of cellular component organization is_a: GO:1902903 ! regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0097435 ! negatively regulates supramolecular fiber organization relationship: RO:0002212 GO:0097435 ! negatively regulates supramolecular fiber organization creation_date: 2014-04-15T16:46:42Z [Term] id: GO:1902905 name: positive regulation of supramolecular fiber organization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of supramolecular fiber organization." [GO_REF:0000058, GOC:PARL, GOC:rl, GOC:TermGenie, PMID:23921388] is_a: GO:0051130 ! positive regulation of cellular component organization is_a: GO:1902903 ! regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0097435 ! positively regulates supramolecular fiber organization relationship: RO:0002213 GO:0097435 ! positively regulates supramolecular fiber organization creation_date: 2014-04-15T16:46:48Z [Term] id: GO:1902913 name: positive regulation of neuroepithelial cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of neuroepithelial cell differentiation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16916506] synonym: "up regulation of neuroepithelial cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of neuroepithelial cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of neuroepithelial cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0030858 ! positive regulation of epithelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060563 ! positively regulates neuroepithelial cell differentiation relationship: RO:0002213 GO:0060563 ! positively regulates neuroepithelial cell differentiation creation_date: 2014-04-18T21:06:42Z [Term] id: GO:1903008 name: organelle disassembly namespace: biological_process def: "The disaggregation of an organelle into its constituent components." [GO_REF:0000079, GOC:TermGenie] synonym: "organelle degradation" EXACT [] is_a: GO:0006996 ! organelle organization is_a: GO:0022411 ! cellular component disassembly intersection_of: GO:0022411 ! cellular component disassembly intersection_of: RO:0002590 GO:0043226 ! results in disassembly of organelle relationship: RO:0002590 GO:0043226 ! results in disassembly of organelle creation_date: 2014-05-13T12:36:03Z [Term] id: GO:1903010 name: regulation of bone development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of bone development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:22510437] is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060348 ! regulates (processual) bone development relationship: RO:0002211 GO:0060348 ! regulates (processual) bone development creation_date: 2014-05-13T22:41:53Z [Term] id: GO:1903011 name: negative regulation of bone development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of bone development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:22510437] synonym: "down regulation of bone development" EXACT [GOC:TermGenie] synonym: "down-regulation of bone development" EXACT [GOC:TermGenie] synonym: "downregulation of bone development" EXACT [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1903010 ! regulation of bone development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060348 ! negatively regulates bone development relationship: RO:0002212 GO:0060348 ! negatively regulates bone development creation_date: 2014-05-13T22:42:00Z [Term] id: GO:1903012 name: positive regulation of bone development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of bone development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:22510437] synonym: "up regulation of bone development" EXACT [GOC:TermGenie] synonym: "up-regulation of bone development" EXACT [GOC:TermGenie] synonym: "upregulation of bone development" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1903010 ! regulation of bone development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060348 ! positively regulates bone development relationship: RO:0002213 GO:0060348 ! positively regulates bone development creation_date: 2014-05-13T22:42:06Z [Term] id: GO:1903018 name: regulation of glycoprotein metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of glycoprotein metabolic process." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:23544079] synonym: "regulation of glycoprotein metabolism" EXACT [GOC:TermGenie] is_a: GO:0060255 ! regulation of macromolecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0009100 ! regulates (processual) glycoprotein metabolic process relationship: RO:0002211 GO:0009100 ! regulates (processual) glycoprotein metabolic process creation_date: 2014-05-14T18:44:19Z [Term] id: GO:1903019 name: negative regulation of glycoprotein metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of glycoprotein metabolic process." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:23544079] synonym: "down regulation of glycoprotein metabolic process" EXACT [GOC:TermGenie] synonym: "down regulation of glycoprotein metabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of glycoprotein metabolic process" EXACT [GOC:TermGenie] synonym: "down-regulation of glycoprotein metabolism" EXACT [GOC:TermGenie] synonym: "downregulation of glycoprotein metabolic process" EXACT [GOC:TermGenie] synonym: "downregulation of glycoprotein metabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of glycoprotein metabolism" EXACT [GOC:TermGenie] is_a: GO:0010605 ! negative regulation of macromolecule metabolic process is_a: GO:1903018 ! regulation of glycoprotein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0009100 ! negatively regulates glycoprotein metabolic process relationship: RO:0002212 GO:0009100 ! negatively regulates glycoprotein metabolic process creation_date: 2014-05-14T18:44:25Z [Term] id: GO:1903020 name: positive regulation of glycoprotein metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of glycoprotein metabolic process." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:23544079] synonym: "positive regulation of glycoprotein metabolism" EXACT [GOC:TermGenie] synonym: "up regulation of glycoprotein metabolic process" EXACT [GOC:TermGenie] synonym: "up regulation of glycoprotein metabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of glycoprotein metabolic process" EXACT [GOC:TermGenie] synonym: "up-regulation of glycoprotein metabolism" EXACT [GOC:TermGenie] synonym: "upregulation of glycoprotein metabolic process" EXACT [GOC:TermGenie] synonym: "upregulation of glycoprotein metabolism" EXACT [GOC:TermGenie] is_a: GO:0010604 ! positive regulation of macromolecule metabolic process is_a: GO:1903018 ! regulation of glycoprotein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0009100 ! positively regulates glycoprotein metabolic process relationship: RO:0002213 GO:0009100 ! positively regulates glycoprotein metabolic process creation_date: 2014-05-14T18:44:31Z [Term] id: GO:1903037 name: regulation of leukocyte cell-cell adhesion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of leukocyte cell-cell adhesion." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21106532] synonym: "regulation of leukocyte adhesion" EXACT [GOC:TermGenie] synonym: "regulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] is_a: GO:0022407 ! regulation of cell-cell adhesion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007159 ! regulates (processual) leukocyte cell-cell adhesion relationship: RO:0002211 GO:0007159 ! regulates (processual) leukocyte cell-cell adhesion creation_date: 2014-05-19T15:29:58Z [Term] id: GO:1903038 name: negative regulation of leukocyte cell-cell adhesion namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte cell-cell adhesion." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21106532] synonym: "down regulation of leukocyte adhesion" EXACT [GOC:TermGenie] synonym: "down regulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] synonym: "down regulation of leukocyte cell-cell adhesion" EXACT [GOC:TermGenie] synonym: "down-regulation of leukocyte adhesion" EXACT [GOC:TermGenie] synonym: "down-regulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] synonym: "down-regulation of leukocyte cell-cell adhesion" EXACT [GOC:TermGenie] synonym: "downregulation of leukocyte adhesion" EXACT [GOC:TermGenie] synonym: "downregulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] synonym: "downregulation of leukocyte cell-cell adhesion" EXACT [GOC:TermGenie] synonym: "negative regulation of leukocyte adhesion" EXACT [GOC:TermGenie] synonym: "negative regulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] is_a: GO:0022408 ! negative regulation of cell-cell adhesion is_a: GO:1903037 ! regulation of leukocyte cell-cell adhesion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007159 ! negatively regulates leukocyte cell-cell adhesion relationship: RO:0002212 GO:0007159 ! negatively regulates leukocyte cell-cell adhesion creation_date: 2014-05-19T15:30:05Z [Term] id: GO:1903039 name: positive regulation of leukocyte cell-cell adhesion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of leukocyte cell-cell adhesion." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21106532] synonym: "positive regulation of leukocyte adhesion" EXACT [GOC:TermGenie] synonym: "positive regulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] synonym: "up regulation of leukocyte adhesion" EXACT [GOC:TermGenie] synonym: "up regulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] synonym: "up regulation of leukocyte cell-cell adhesion" EXACT [GOC:TermGenie] synonym: "up-regulation of leukocyte adhesion" EXACT [GOC:TermGenie] synonym: "up-regulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] synonym: "up-regulation of leukocyte cell-cell adhesion" EXACT [GOC:TermGenie] synonym: "upregulation of leukocyte adhesion" EXACT [GOC:TermGenie] synonym: "upregulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] synonym: "upregulation of leukocyte cell-cell adhesion" EXACT [GOC:TermGenie] is_a: GO:0022409 ! positive regulation of cell-cell adhesion is_a: GO:1903037 ! regulation of leukocyte cell-cell adhesion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007159 ! positively regulates leukocyte cell-cell adhesion relationship: RO:0002213 GO:0007159 ! positively regulates leukocyte cell-cell adhesion creation_date: 2014-05-19T15:30:15Z [Term] id: GO:1903045 name: neural crest cell migration involved in sympathetic nervous system development namespace: biological_process def: "Any neural crest cell migration that is involved in sympathetic nervous system development." [GO_REF:0000060, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:19325129] is_a: GO:1901166 ! neural crest cell migration involved in autonomic nervous system development intersection_of: GO:0001755 ! neural crest cell migration intersection_of: BFO:0000050 GO:0048485 ! part of sympathetic nervous system development relationship: BFO:0000050 GO:0048485 ! part of sympathetic nervous system development creation_date: 2014-05-22T07:06:02Z [Term] id: GO:1903046 name: meiotic cell cycle process namespace: biological_process def: "A process that is part of the meiotic cell cycle." [GO_REF:0000060, GOC:mtg_cell_cycle, GOC:TermGenie] is_a: GO:0022402 ! cell cycle process is_a: GO:0022414 ! reproductive process intersection_of: GO:0009987 ! cellular process intersection_of: BFO:0000050 GO:0051321 ! part of meiotic cell cycle disjoint_from: GO:1903047 ! mitotic cell cycle process relationship: BFO:0000050 GO:0051321 ! part of meiotic cell cycle creation_date: 2014-05-22T14:22:28Z [Term] id: GO:1903047 name: mitotic cell cycle process namespace: biological_process def: "A process that is part of the mitotic cell cycle." [GO_REF:0000060, GOC:mtg_cell_cycle, GOC:TermGenie] is_a: GO:0022402 ! cell cycle process intersection_of: GO:0009987 ! cellular process intersection_of: BFO:0000050 GO:0000278 ! part of mitotic cell cycle relationship: BFO:0000050 GO:0000278 ! part of mitotic cell cycle creation_date: 2014-05-22T14:22:34Z [Term] id: GO:1903053 name: regulation of extracellular matrix organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of extracellular matrix organization." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:22357537] synonym: "regulation of extracellular matrix organisation" EXACT [GOC:TermGenie] is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030198 ! regulates (processual) extracellular matrix organization relationship: RO:0002211 GO:0030198 ! regulates (processual) extracellular matrix organization creation_date: 2014-05-23T17:15:41Z [Term] id: GO:1903054 name: negative regulation of extracellular matrix organization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix organization." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:22357537] synonym: "down regulation of extracellular matrix organisation" EXACT [GOC:TermGenie] synonym: "down regulation of extracellular matrix organization" EXACT [GOC:TermGenie] synonym: "down-regulation of extracellular matrix organisation" EXACT [GOC:TermGenie] synonym: "down-regulation of extracellular matrix organization" EXACT [GOC:TermGenie] synonym: "downregulation of extracellular matrix organisation" EXACT [GOC:TermGenie] synonym: "downregulation of extracellular matrix organization" EXACT [GOC:TermGenie] synonym: "negative regulation of extracellular matrix organisation" EXACT [GOC:TermGenie] is_a: GO:0051129 ! negative regulation of cellular component organization is_a: GO:1903053 ! regulation of extracellular matrix organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030198 ! negatively regulates extracellular matrix organization relationship: RO:0002212 GO:0030198 ! negatively regulates extracellular matrix organization creation_date: 2014-05-23T17:15:47Z [Term] id: GO:1903055 name: positive regulation of extracellular matrix organization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of extracellular matrix organization." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:22357537] synonym: "positive regulation of extracellular matrix organisation" EXACT [GOC:TermGenie] synonym: "up regulation of extracellular matrix organisation" EXACT [GOC:TermGenie] synonym: "up regulation of extracellular matrix organization" EXACT [GOC:TermGenie] synonym: "up-regulation of extracellular matrix organisation" EXACT [GOC:TermGenie] synonym: "up-regulation of extracellular matrix organization" EXACT [GOC:TermGenie] synonym: "upregulation of extracellular matrix organisation" EXACT [GOC:TermGenie] synonym: "upregulation of extracellular matrix organization" EXACT [GOC:TermGenie] is_a: GO:0051130 ! positive regulation of cellular component organization is_a: GO:1903053 ! regulation of extracellular matrix organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030198 ! positively regulates extracellular matrix organization relationship: RO:0002213 GO:0030198 ! positively regulates extracellular matrix organization creation_date: 2014-05-23T17:15:53Z [Term] id: GO:1903076 name: regulation of protein localization to plasma membrane namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein localization to plasma membrane." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:11602640] synonym: "regulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] is_a: GO:1904375 ! regulation of protein localization to cell periphery is_a: GO:1905475 ! regulation of protein localization to membrane intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0072659 ! regulates (processual) protein localization to plasma membrane relationship: RO:0002211 GO:0072659 ! regulates (processual) protein localization to plasma membrane creation_date: 2009-07-10T10:32:44Z [Term] id: GO:1903077 name: negative regulation of protein localization to plasma membrane namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to plasma membrane." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:11602640] synonym: "down regulation of protein localisation in plasma membrane" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization to plasma membrane" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation in plasma membrane" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to plasma membrane" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation in plasma membrane" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to plasma membrane" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] is_a: GO:1903076 ! regulation of protein localization to plasma membrane is_a: GO:1904376 ! negative regulation of protein localization to cell periphery is_a: GO:1905476 ! negative regulation of protein localization to membrane intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0072659 ! negatively regulates protein localization to plasma membrane relationship: RO:0002212 GO:0072659 ! negatively regulates protein localization to plasma membrane creation_date: 2014-05-29T17:10:16Z [Term] id: GO:1903078 name: positive regulation of protein localization to plasma membrane namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein localization to plasma membrane." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:11602640] synonym: "positive regulation of protein localisation in plasma membrane" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation in plasma membrane" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization to plasma membrane" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation in plasma membrane" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to plasma membrane" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation in plasma membrane" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to plasma membrane" EXACT [GOC:TermGenie] is_a: GO:1903076 ! regulation of protein localization to plasma membrane is_a: GO:1904377 ! positive regulation of protein localization to cell periphery is_a: GO:1905477 ! positive regulation of protein localization to membrane intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0072659 ! positively regulates protein localization to plasma membrane relationship: RO:0002213 GO:0072659 ! positively regulates protein localization to plasma membrane creation_date: 2009-07-10T10:34:17Z [Term] id: GO:1903115 name: regulation of actin filament-based movement namespace: biological_process def: "Any process that modulates the frequency, rate or extent of actin filament-based movement." [GO_REF:0000058, GOC:TermGenie, PMID:24798735] is_a: GO:0032970 ! regulation of actin filament-based process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030048 ! regulates (processual) actin filament-based movement relationship: RO:0002211 GO:0030048 ! regulates (processual) actin filament-based movement creation_date: 2014-06-12T16:55:57Z [Term] id: GO:1903116 name: positive regulation of actin filament-based movement namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of actin filament-based movement." [GO_REF:0000058, GOC:TermGenie, PMID:24798735] synonym: "up regulation of actin filament-based movement" EXACT [GOC:TermGenie] synonym: "up-regulation of actin filament-based movement" EXACT [GOC:TermGenie] synonym: "upregulation of actin filament-based movement" EXACT [GOC:TermGenie] is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:1903115 ! regulation of actin filament-based movement intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030048 ! positively regulates actin filament-based movement relationship: RO:0002213 GO:0030048 ! positively regulates actin filament-based movement creation_date: 2014-06-12T16:56:04Z [Term] id: GO:1903119 name: protein localization to actin cytoskeleton namespace: biological_process def: "A process in which a protein is transported to, or maintained in, the location of an actin cytoskeleton." [GO_REF:0000087, GOC:TermGenie, PMID:24798735] synonym: "protein localisation in actin cytoskeleton" EXACT [GOC:TermGenie] synonym: "protein localisation to actin cytoskeleton" EXACT [GOC:TermGenie] synonym: "protein localization in actin cytoskeleton" EXACT [GOC:TermGenie] is_a: GO:0044380 ! protein localization to cytoskeleton intersection_of: GO:0008104 ! protein localization intersection_of: RO:0002339 GO:0015629 ! has target end location actin cytoskeleton relationship: RO:0002339 GO:0015629 ! has target end location actin cytoskeleton creation_date: 2014-06-16T11:27:09Z [Term] id: GO:1903120 name: protein localization to actin filament bundle namespace: biological_process def: "A process in which a protein is transported to, or maintained in, the location of an actin filament bundle." [GO_REF:0000087, GOC:TermGenie, PMID:24798735] synonym: "protein localisation in actin filament bundle" EXACT [GOC:TermGenie] synonym: "protein localisation to actin filament bundle" EXACT [GOC:TermGenie] synonym: "protein localization in actin filament bundle" EXACT [GOC:TermGenie] is_a: GO:1903119 ! protein localization to actin cytoskeleton intersection_of: GO:0008104 ! protein localization intersection_of: RO:0002339 GO:0032432 ! has target end location actin filament bundle relationship: RO:0002339 GO:0032432 ! has target end location actin filament bundle creation_date: 2014-06-16T11:27:16Z [Term] id: GO:1903131 name: mononuclear cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized features of a mononuclear cell." [CL:0000842, GO_REF:0000086, GOC:TermGenie, PMID:24759906] is_a: GO:0002521 ! leukocyte differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000842 ! results in acquisition of features of mononuclear cell relationship: RO:0002315 CL:0000842 ! results in acquisition of features of mononuclear cell creation_date: 2014-06-25T15:47:09Z [Term] id: GO:1903224 name: regulation of endodermal cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of endodermal cell differentiation." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23154389] synonym: "regulation of endoderm cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0035987 ! regulates (processual) endodermal cell differentiation relationship: RO:0002211 GO:0035987 ! regulates (processual) endodermal cell differentiation creation_date: 2014-07-29T13:22:35Z [Term] id: GO:1903225 name: negative regulation of endodermal cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of endodermal cell differentiation." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23154389] synonym: "down regulation of endoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of endodermal cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of endoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of endodermal cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of endoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of endodermal cell differentiation" EXACT [GOC:TermGenie] synonym: "negative regulation of endoderm cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:1903224 ! regulation of endodermal cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0035987 ! negatively regulates endodermal cell differentiation relationship: RO:0002212 GO:0035987 ! negatively regulates endodermal cell differentiation creation_date: 2014-07-29T13:22:41Z [Term] id: GO:1903226 name: positive regulation of endodermal cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of endodermal cell differentiation." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23154389] synonym: "positive regulation of endoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of endoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of endodermal cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of endoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of endodermal cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of endoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of endodermal cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:1903224 ! regulation of endodermal cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0035987 ! positively regulates endodermal cell differentiation relationship: RO:0002213 GO:0035987 ! positively regulates endodermal cell differentiation creation_date: 2014-07-29T13:22:47Z [Term] id: GO:1903292 name: protein localization to Golgi membrane namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within a Golgi membrane." [GO_REF:0000087, GOC:TermGenie, PMID:11378902] synonym: "protein localisation in Golgi membrane" EXACT [GOC:TermGenie] synonym: "protein localisation to Golgi membrane" EXACT [GOC:TermGenie] synonym: "protein localization in Golgi membrane" EXACT [GOC:TermGenie] is_a: GO:0034067 ! protein localization to Golgi apparatus is_a: GO:0072657 ! protein localization to membrane intersection_of: GO:0008104 ! protein localization intersection_of: RO:0002339 GO:0000139 ! has target end location Golgi membrane relationship: RO:0002339 GO:0000139 ! has target end location Golgi membrane creation_date: 2014-08-12T14:22:31Z [Term] id: GO:1903335 name: regulation of vacuolar transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of vacuolar transport." [GO_REF:0000058, GOC:TermGenie, GOC:vw] is_a: GO:0032386 ! regulation of intracellular transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007034 ! regulates (processual) vacuolar transport relationship: RO:0002211 GO:0007034 ! regulates (processual) vacuolar transport creation_date: 2014-08-18T13:16:04Z [Term] id: GO:1903336 name: negative regulation of vacuolar transport namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of vacuolar transport." [GO_REF:0000058, GOC:TermGenie, GOC:vw] synonym: "down regulation of vacuolar transport" EXACT [GOC:TermGenie] synonym: "down-regulation of vacuolar transport" EXACT [GOC:TermGenie] synonym: "downregulation of vacuolar transport" EXACT [GOC:TermGenie] is_a: GO:0032387 ! negative regulation of intracellular transport is_a: GO:1903335 ! regulation of vacuolar transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007034 ! negatively regulates vacuolar transport relationship: RO:0002212 GO:0007034 ! negatively regulates vacuolar transport creation_date: 2014-08-18T13:16:11Z [Term] id: GO:1903337 name: positive regulation of vacuolar transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of vacuolar transport." [GO_REF:0000058, GOC:TermGenie, GOC:vw] synonym: "up regulation of vacuolar transport" EXACT [GOC:TermGenie] synonym: "up-regulation of vacuolar transport" EXACT [GOC:TermGenie] synonym: "upregulation of vacuolar transport" EXACT [GOC:TermGenie] is_a: GO:0032388 ! positive regulation of intracellular transport is_a: GO:1903335 ! regulation of vacuolar transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007034 ! positively regulates vacuolar transport relationship: RO:0002213 GO:0007034 ! positively regulates vacuolar transport creation_date: 2014-08-18T13:16:19Z [Term] id: GO:1903353 name: regulation of nucleus organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of nucleus organization." [GO_REF:0000058, GOC:TermGenie, PMID:16943282] synonym: "regulation of nuclear organisation" EXACT [GOC:TermGenie] synonym: "regulation of nuclear organization" EXACT [GOC:TermGenie] is_a: GO:0033043 ! regulation of organelle organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006997 ! regulates (processual) nucleus organization relationship: RO:0002211 GO:0006997 ! regulates (processual) nucleus organization creation_date: 2014-08-20T19:36:16Z [Term] id: GO:1903358 name: regulation of Golgi organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of Golgi organization." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:17562788] synonym: "regulation of Golgi organisation" EXACT [GOC:TermGenie] is_a: GO:0033043 ! regulation of organelle organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007030 ! regulates (processual) Golgi organization relationship: RO:0002211 GO:0007030 ! regulates (processual) Golgi organization creation_date: 2014-08-21T10:22:22Z [Term] id: GO:1903379 name: regulation of mitotic chromosome condensation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mitotic chromosome condensation." [GO_REF:0000058, GOC:TermGenie, PMID:9490640] is_a: GO:0010564 ! regulation of cell cycle process is_a: GO:0060623 ! regulation of chromosome condensation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007076 ! regulates (processual) mitotic chromosome condensation relationship: RO:0002211 GO:0007076 ! regulates (processual) mitotic chromosome condensation creation_date: 2014-08-26T13:57:13Z [Term] id: GO:1903380 name: positive regulation of mitotic chromosome condensation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mitotic chromosome condensation." [GO_REF:0000058, GOC:TermGenie, PMID:9490640] synonym: "up regulation of mitotic chromosome condensation" EXACT [GOC:TermGenie] synonym: "up-regulation of mitotic chromosome condensation" EXACT [GOC:TermGenie] synonym: "upregulation of mitotic chromosome condensation" EXACT [GOC:TermGenie] is_a: GO:0090068 ! positive regulation of cell cycle process is_a: GO:1903379 ! regulation of mitotic chromosome condensation is_a: GO:1905821 ! positive regulation of chromosome condensation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007076 ! positively regulates mitotic chromosome condensation relationship: RO:0002213 GO:0007076 ! positively regulates mitotic chromosome condensation creation_date: 2014-08-26T13:57:29Z [Term] id: GO:1903412 name: response to bile acid namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus." [GO_REF:0000071, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21757002] is_a: GO:0014070 ! response to organic cyclic compound is_a: GO:0033993 ! response to lipid is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:3098 ! has primary input bile acid relationship: RO:0004009 CHEBI:3098 ! has primary input bile acid creation_date: 2014-09-03T12:45:43Z [Term] id: GO:1903429 name: regulation of cell maturation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell maturation." [GO_REF:0000058, GOC:TermGenie, PMID:17459944] is_a: GO:0060284 ! regulation of cell development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048469 ! regulates (processual) cell maturation relationship: RO:0002211 GO:0048469 ! regulates (processual) cell maturation creation_date: 2014-09-15T13:31:23Z [Term] id: GO:1903430 name: negative regulation of cell maturation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell maturation." [GO_REF:0000058, GOC:TermGenie, PMID:17459944] synonym: "down regulation of cell maturation" EXACT [GOC:TermGenie] synonym: "down-regulation of cell maturation" EXACT [GOC:TermGenie] synonym: "downregulation of cell maturation" EXACT [GOC:TermGenie] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:1903429 ! regulation of cell maturation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048469 ! negatively regulates cell maturation relationship: RO:0002212 GO:0048469 ! negatively regulates cell maturation creation_date: 2014-09-15T13:31:32Z [Term] id: GO:1903431 name: positive regulation of cell maturation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell maturation." [GO_REF:0000058, GOC:TermGenie, PMID:17459944] synonym: "up regulation of cell maturation" EXACT [GOC:TermGenie] synonym: "up-regulation of cell maturation" EXACT [GOC:TermGenie] synonym: "upregulation of cell maturation" EXACT [GOC:TermGenie] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:1903429 ! regulation of cell maturation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0048469 ! positively regulates cell maturation relationship: RO:0002213 GO:0048469 ! positively regulates cell maturation creation_date: 2014-09-15T13:31:41Z [Term] id: GO:1903441 name: protein localization to ciliary membrane namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within a ciliary membrane." [GO_REF:0000087, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:22139371] synonym: "protein localisation in ciliary membrane" EXACT [GOC:TermGenie] synonym: "protein localisation to ciliary membrane" EXACT [GOC:TermGenie] synonym: "protein localization in ciliary membrane" EXACT [GOC:TermGenie] is_a: GO:0061512 ! protein localization to cilium is_a: GO:0072657 ! protein localization to membrane is_a: GO:1990778 ! protein localization to cell periphery intersection_of: GO:0008104 ! protein localization intersection_of: RO:0002339 GO:0060170 ! has target end location ciliary membrane relationship: RO:0002339 GO:0060170 ! has target end location ciliary membrane creation_date: 2014-09-16T15:15:39Z [Term] id: GO:1903510 name: mucopolysaccharide metabolic process namespace: biological_process def: "The chemical reactions and pathways involving mucopolysaccharide." [GO_REF:0000068, GOC:dph, GOC:TermGenie, PMID:4236091] synonym: "mucopolysaccharide metabolism" EXACT [GOC:TermGenie] is_a: GO:0030203 ! glycosaminoglycan metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:37395 ! has primary input or output mucopolysaccharide relationship: RO:0004007 CHEBI:37395 ! has primary input or output mucopolysaccharide creation_date: 2014-10-01T21:55:47Z [Term] id: GO:1903522 name: regulation of blood circulation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of blood circulation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:10659969] is_a: GO:0044057 ! regulation of system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0008015 ! regulates (processual) blood circulation relationship: RO:0002211 GO:0008015 ! regulates (processual) blood circulation creation_date: 2014-10-06T18:38:56Z [Term] id: GO:1903523 name: negative regulation of blood circulation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of blood circulation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:10659969] synonym: "down regulation of blood circulation" EXACT [GOC:TermGenie] synonym: "down-regulation of blood circulation" EXACT [GOC:TermGenie] synonym: "downregulation of blood circulation" EXACT [GOC:TermGenie] is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1903522 ! regulation of blood circulation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0008015 ! negatively regulates blood circulation relationship: RO:0002212 GO:0008015 ! negatively regulates blood circulation creation_date: 2014-10-06T18:39:05Z [Term] id: GO:1903524 name: positive regulation of blood circulation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of blood circulation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:10659969] synonym: "up regulation of blood circulation" EXACT [GOC:TermGenie] synonym: "up-regulation of blood circulation" EXACT [GOC:TermGenie] synonym: "upregulation of blood circulation" EXACT [GOC:TermGenie] is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1903522 ! regulation of blood circulation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0008015 ! positively regulates blood circulation relationship: RO:0002213 GO:0008015 ! positively regulates blood circulation creation_date: 2014-10-06T18:39:13Z [Term] id: GO:1903530 name: regulation of secretion by cell namespace: biological_process def: "Any process that modulates the frequency, rate or extent of secretion by cell." [GO_REF:0000058, GOC:pm, GOC:TermGenie, PMID:12130530] synonym: "regulation of cellular secretion" EXACT [GOC:TermGenie] is_a: GO:0050794 ! regulation of cellular process is_a: GO:0051046 ! regulation of secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0032940 ! regulates (processual) secretion by cell relationship: RO:0002211 GO:0032940 ! regulates (processual) secretion by cell creation_date: 2014-10-08T13:24:59Z [Term] id: GO:1903531 name: negative regulation of secretion by cell namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of secretion by cell." [GO_REF:0000058, GOC:pm, GOC:TermGenie, PMID:12130530] synonym: "down regulation of cellular secretion" EXACT [GOC:TermGenie] synonym: "down regulation of secretion by cell" EXACT [GOC:TermGenie] synonym: "down-regulation of cellular secretion" EXACT [GOC:TermGenie] synonym: "down-regulation of secretion by cell" EXACT [GOC:TermGenie] synonym: "downregulation of cellular secretion" EXACT [GOC:TermGenie] synonym: "downregulation of secretion by cell" EXACT [GOC:TermGenie] synonym: "negative regulation of cellular secretion" EXACT [GOC:TermGenie] is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:0051048 ! negative regulation of secretion is_a: GO:1903530 ! regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0032940 ! negatively regulates secretion by cell relationship: RO:0002212 GO:0032940 ! negatively regulates secretion by cell creation_date: 2014-10-08T13:25:08Z [Term] id: GO:1903532 name: positive regulation of secretion by cell namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of secretion by cell." [GO_REF:0000058, GOC:pm, GOC:TermGenie, PMID:12130530] synonym: "positive regulation of cellular secretion" EXACT [GOC:TermGenie] synonym: "up regulation of cellular secretion" EXACT [GOC:TermGenie] synonym: "up regulation of secretion by cell" EXACT [GOC:TermGenie] synonym: "up-regulation of cellular secretion" EXACT [GOC:TermGenie] synonym: "up-regulation of secretion by cell" EXACT [GOC:TermGenie] synonym: "upregulation of cellular secretion" EXACT [GOC:TermGenie] synonym: "upregulation of secretion by cell" EXACT [GOC:TermGenie] is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:0051047 ! positive regulation of secretion is_a: GO:1903530 ! regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0032940 ! positively regulates secretion by cell relationship: RO:0002213 GO:0032940 ! positively regulates secretion by cell creation_date: 2014-10-08T13:25:17Z [Term] id: GO:1903537 name: meiotic cell cycle process involved in oocyte maturation namespace: biological_process def: "Any meiotic cell cycle process that is involved in oocyte maturation." [GO_REF:0000060, GOC:jz, GOC:TermGenie, PMID:25212395] is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:1903046 ! meiotic cell cycle process intersection_of: GO:1903046 ! meiotic cell cycle process intersection_of: BFO:0000050 GO:0001556 ! part of oocyte maturation relationship: BFO:0000050 GO:0001556 ! part of oocyte maturation creation_date: 2014-10-09T10:46:14Z [Term] id: GO:1903538 name: regulation of meiotic cell cycle process involved in oocyte maturation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation." [GO_REF:0000058, GOC:jz, GOC:TermGenie, PMID:25212395] is_a: GO:0010564 ! regulation of cell cycle process is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1903537 ! regulates (processual) meiotic cell cycle process involved in oocyte maturation relationship: RO:0002211 GO:1903537 ! regulates (processual) meiotic cell cycle process involved in oocyte maturation creation_date: 2014-10-09T10:52:38Z [Term] id: GO:1903541 name: regulation of exosomal secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of exosomal secretion." [GO_REF:0000058, GOC:TermGenie, PMID:24105262] synonym: "regulation of exosomal secretory pathway" EXACT [GOC:TermGenie] synonym: "regulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] synonym: "regulation of secretion of exosome" EXACT [GOC:TermGenie] is_a: GO:0017157 ! regulation of exocytosis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1990182 ! regulates (processual) exosomal secretion relationship: RO:0002211 GO:1990182 ! regulates (processual) exosomal secretion creation_date: 2014-10-14T11:38:52Z [Term] id: GO:1903542 name: negative regulation of exosomal secretion namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of exosomal secretion." [GO_REF:0000058, GOC:TermGenie, PMID:24105262] synonym: "down regulation of exosomal secretion" EXACT [GOC:TermGenie] synonym: "down regulation of exosomal secretory pathway" EXACT [GOC:TermGenie] synonym: "down regulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] synonym: "down regulation of secretion of exosome" EXACT [GOC:TermGenie] synonym: "down-regulation of exosomal secretion" EXACT [GOC:TermGenie] synonym: "down-regulation of exosomal secretory pathway" EXACT [GOC:TermGenie] synonym: "down-regulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] synonym: "down-regulation of secretion of exosome" EXACT [GOC:TermGenie] synonym: "downregulation of exosomal secretion" EXACT [GOC:TermGenie] synonym: "downregulation of exosomal secretory pathway" EXACT [GOC:TermGenie] synonym: "downregulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] synonym: "downregulation of secretion of exosome" EXACT [GOC:TermGenie] synonym: "negative regulation of exosomal secretory pathway" EXACT [GOC:TermGenie] synonym: "negative regulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] synonym: "negative regulation of secretion of exosome" EXACT [GOC:TermGenie] is_a: GO:0045920 ! negative regulation of exocytosis is_a: GO:1903541 ! regulation of exosomal secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1990182 ! negatively regulates exosomal secretion relationship: RO:0002212 GO:1990182 ! negatively regulates exosomal secretion creation_date: 2014-10-14T11:39:02Z [Term] id: GO:1903543 name: positive regulation of exosomal secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of exosomal secretion." [GO_REF:0000058, GOC:TermGenie, PMID:24105262] synonym: "positive regulation of exosomal secretory pathway" EXACT [GOC:TermGenie] synonym: "positive regulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] synonym: "positive regulation of secretion of exosome" EXACT [GOC:TermGenie] synonym: "up regulation of exosomal secretion" EXACT [GOC:TermGenie] synonym: "up regulation of exosomal secretory pathway" EXACT [GOC:TermGenie] synonym: "up regulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] synonym: "up regulation of secretion of exosome" EXACT [GOC:TermGenie] synonym: "up-regulation of exosomal secretion" EXACT [GOC:TermGenie] synonym: "up-regulation of exosomal secretory pathway" EXACT [GOC:TermGenie] synonym: "up-regulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] synonym: "up-regulation of secretion of exosome" EXACT [GOC:TermGenie] synonym: "upregulation of exosomal secretion" EXACT [GOC:TermGenie] synonym: "upregulation of exosomal secretory pathway" EXACT [GOC:TermGenie] synonym: "upregulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] synonym: "upregulation of secretion of exosome" EXACT [GOC:TermGenie] is_a: GO:0044089 ! positive regulation of cellular component biogenesis is_a: GO:0045921 ! positive regulation of exocytosis is_a: GO:1903541 ! regulation of exosomal secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1990182 ! positively regulates exosomal secretion relationship: RO:0002213 GO:1990182 ! positively regulates exosomal secretion creation_date: 2014-10-14T11:39:10Z [Term] id: GO:1903551 name: regulation of extracellular exosome assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of extracellular vesicular exosome assembly." [GO_REF:0000058, GOC:TermGenie, PMID:24105262] synonym: "regulation of extracellular vesicular exosome assembly" EXACT [GOC:vesicles] is_a: GO:1902115 ! regulation of organelle assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0071971 ! regulates (processual) extracellular exosome assembly relationship: RO:0002211 GO:0071971 ! regulates (processual) extracellular exosome assembly creation_date: 2014-10-20T15:37:25Z [Term] id: GO:1903552 name: negative regulation of extracellular exosome assembly namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of extracellular vesicular exosome assembly." [GO_REF:0000058, GOC:TermGenie, PMID:24105262] synonym: "down regulation of extracellular vesicular exosome assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of extracellular vesicular exosome assembly" EXACT [GOC:TermGenie] synonym: "downregulation of extracellular vesicular exosome assembly" EXACT [GOC:TermGenie] synonym: "negative regulation of extracellular vesicular exosome assembly" EXACT [GOC:vesicles] is_a: GO:1902116 ! negative regulation of organelle assembly is_a: GO:1903551 ! regulation of extracellular exosome assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0071971 ! negatively regulates extracellular exosome assembly relationship: RO:0002212 GO:0071971 ! negatively regulates extracellular exosome assembly creation_date: 2014-10-20T15:37:33Z [Term] id: GO:1903553 name: positive regulation of extracellular exosome assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of extracellular vesicular exosome assembly." [GO_REF:0000058, GOC:TermGenie, PMID:24105262] synonym: "up regulation of extracellular vesicular exosome assembly" EXACT [GOC:TermGenie] synonym: "up-regulation of extracellular vesicular exosome assembly" EXACT [GOC:TermGenie] synonym: "upregulation of extracellular vesicular exosome assembly" EXACT [GOC:TermGenie] is_a: GO:1902117 ! positive regulation of organelle assembly is_a: GO:1903551 ! regulation of extracellular exosome assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0071971 ! positively regulates extracellular exosome assembly relationship: RO:0002213 GO:0071971 ! positively regulates extracellular exosome assembly creation_date: 2014-10-20T15:37:42Z [Term] id: GO:1903561 name: extracellular vesicle namespace: cellular_component def: "Any vesicle that is part of the extracellular region." [GO_REF:0000064, GOC:pm, GOC:TermGenie, PMID:24769233] is_a: GO:0031982 ! vesicle is_a: GO:0065010 ! extracellular membrane-bounded organelle intersection_of: GO:0031982 ! vesicle intersection_of: BFO:0000050 GO:0005576 ! part of extracellular region creation_date: 2014-10-22T14:26:11Z [Term] id: GO:1903564 name: regulation of protein localization to cilium namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein localization to cilium." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:22072986] is_a: GO:0032880 ! regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0061512 ! regulates (processual) protein localization to cilium relationship: RO:0002211 GO:0061512 ! regulates (processual) protein localization to cilium creation_date: 2014-10-24T20:58:11Z [Term] id: GO:1903565 name: negative regulation of protein localization to cilium namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cilium." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:22072986] synonym: "down regulation of protein localization to cilium" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to cilium" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to cilium" EXACT [GOC:TermGenie] is_a: GO:1903564 ! regulation of protein localization to cilium is_a: GO:1903828 ! negative regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0061512 ! negatively regulates protein localization to cilium relationship: RO:0002212 GO:0061512 ! negatively regulates protein localization to cilium creation_date: 2014-10-24T20:58:20Z [Term] id: GO:1903566 name: positive regulation of protein localization to cilium namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein localization to cilium." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:22072986] synonym: "up regulation of protein localization to cilium" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to cilium" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to cilium" EXACT [GOC:TermGenie] is_a: GO:1903564 ! regulation of protein localization to cilium is_a: GO:1903829 ! positive regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0061512 ! positively regulates protein localization to cilium relationship: RO:0002213 GO:0061512 ! positively regulates protein localization to cilium creation_date: 2014-10-24T20:58:28Z [Term] id: GO:1903567 name: regulation of protein localization to ciliary membrane namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein localization to ciliary membrane." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:22072986] synonym: "regulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] synonym: "regulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] synonym: "regulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] is_a: GO:1903564 ! regulation of protein localization to cilium is_a: GO:1904375 ! regulation of protein localization to cell periphery is_a: GO:1905475 ! regulation of protein localization to membrane intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1903441 ! regulates (processual) protein localization to ciliary membrane relationship: RO:0002211 GO:1903441 ! regulates (processual) protein localization to ciliary membrane creation_date: 2014-10-24T21:32:51Z [Term] id: GO:1903568 name: negative regulation of protein localization to ciliary membrane namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to ciliary membrane." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:22072986] synonym: "down regulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] synonym: "down regulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization to ciliary membrane" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to ciliary membrane" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to ciliary membrane" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] is_a: GO:1903565 ! negative regulation of protein localization to cilium is_a: GO:1903567 ! regulation of protein localization to ciliary membrane is_a: GO:1904376 ! negative regulation of protein localization to cell periphery is_a: GO:1905476 ! negative regulation of protein localization to membrane intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1903441 ! negatively regulates protein localization to ciliary membrane relationship: RO:0002212 GO:1903441 ! negatively regulates protein localization to ciliary membrane creation_date: 2014-10-24T21:32:59Z [Term] id: GO:1903569 name: positive regulation of protein localization to ciliary membrane namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein localization to ciliary membrane." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:22072986] synonym: "positive regulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization to ciliary membrane" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to ciliary membrane" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to ciliary membrane" EXACT [GOC:TermGenie] is_a: GO:1903566 ! positive regulation of protein localization to cilium is_a: GO:1903567 ! regulation of protein localization to ciliary membrane is_a: GO:1904377 ! positive regulation of protein localization to cell periphery is_a: GO:1905477 ! positive regulation of protein localization to membrane intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1903441 ! positively regulates protein localization to ciliary membrane relationship: RO:0002213 GO:1903441 ! positively regulates protein localization to ciliary membrane creation_date: 2014-10-24T21:33:08Z [Term] id: GO:1903624 name: regulation of DNA catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of DNA catabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:2001740] synonym: "regulation of DNA breakdown" EXACT [GOC:TermGenie] synonym: "regulation of DNA catabolism" EXACT [GOC:TermGenie] synonym: "regulation of DNA degradation" EXACT [GOC:TermGenie] is_a: GO:0031329 ! regulation of cellular catabolic process is_a: GO:0051052 ! regulation of DNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006308 ! regulates (processual) DNA catabolic process relationship: RO:0002211 GO:0006308 ! regulates (processual) DNA catabolic process creation_date: 2014-11-19T22:36:35Z [Term] id: GO:1903625 name: negative regulation of DNA catabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of DNA catabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:2001740] synonym: "down regulation of DNA breakdown" EXACT [GOC:TermGenie] synonym: "down regulation of DNA catabolic process" EXACT [GOC:TermGenie] synonym: "down regulation of DNA catabolism" EXACT [GOC:TermGenie] synonym: "down regulation of DNA degradation" EXACT [GOC:TermGenie] synonym: "down-regulation of DNA breakdown" EXACT [GOC:TermGenie] synonym: "down-regulation of DNA catabolic process" EXACT [GOC:TermGenie] synonym: "down-regulation of DNA catabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of DNA degradation" EXACT [GOC:TermGenie] synonym: "downregulation of DNA breakdown" EXACT [GOC:TermGenie] synonym: "downregulation of DNA catabolic process" EXACT [GOC:TermGenie] synonym: "downregulation of DNA catabolism" EXACT [GOC:TermGenie] synonym: "downregulation of DNA degradation" EXACT [GOC:TermGenie] synonym: "negative regulation of DNA breakdown" EXACT [GOC:TermGenie] synonym: "negative regulation of DNA catabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of DNA degradation" EXACT [GOC:TermGenie] is_a: GO:0031330 ! negative regulation of cellular catabolic process is_a: GO:0051053 ! negative regulation of DNA metabolic process is_a: GO:1903624 ! regulation of DNA catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006308 ! negatively regulates DNA catabolic process relationship: RO:0002212 GO:0006308 ! negatively regulates DNA catabolic process creation_date: 2014-11-19T22:36:43Z [Term] id: GO:1903626 name: positive regulation of DNA catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of DNA catabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:2001740] synonym: "positive regulation of DNA breakdown" EXACT [GOC:TermGenie] synonym: "positive regulation of DNA catabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of DNA degradation" EXACT [GOC:TermGenie] synonym: "up regulation of DNA breakdown" EXACT [GOC:TermGenie] synonym: "up regulation of DNA catabolic process" EXACT [GOC:TermGenie] synonym: "up regulation of DNA catabolism" EXACT [GOC:TermGenie] synonym: "up regulation of DNA degradation" EXACT [GOC:TermGenie] synonym: "up-regulation of DNA breakdown" EXACT [GOC:TermGenie] synonym: "up-regulation of DNA catabolic process" EXACT [GOC:TermGenie] synonym: "up-regulation of DNA catabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of DNA degradation" EXACT [GOC:TermGenie] synonym: "upregulation of DNA breakdown" EXACT [GOC:TermGenie] synonym: "upregulation of DNA catabolic process" EXACT [GOC:TermGenie] synonym: "upregulation of DNA catabolism" EXACT [GOC:TermGenie] synonym: "upregulation of DNA degradation" EXACT [GOC:TermGenie] is_a: GO:0031331 ! positive regulation of cellular catabolic process is_a: GO:0051054 ! positive regulation of DNA metabolic process is_a: GO:1903624 ! regulation of DNA catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006308 ! positively regulates DNA catabolic process relationship: RO:0002213 GO:0006308 ! positively regulates DNA catabolic process creation_date: 2014-11-19T22:36:51Z [Term] id: GO:1903697 name: negative regulation of microvillus assembly namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of microvillus assembly." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:22797597] synonym: "down regulation of microvillus assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of microvillus assembly" EXACT [GOC:TermGenie] synonym: "downregulation of microvillus assembly" EXACT [GOC:TermGenie] is_a: GO:0032534 ! regulation of microvillus assembly is_a: GO:0120033 ! negative regulation of plasma membrane bounded cell projection assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030033 ! negatively regulates microvillus assembly relationship: RO:0002212 GO:0030033 ! negatively regulates microvillus assembly creation_date: 2014-12-03T11:45:08Z [Term] id: GO:1903698 name: positive regulation of microvillus assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of microvillus assembly." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:22797597] synonym: "up regulation of microvillus assembly" EXACT [GOC:TermGenie] synonym: "up-regulation of microvillus assembly" EXACT [GOC:TermGenie] synonym: "upregulation of microvillus assembly" EXACT [GOC:TermGenie] is_a: GO:0032534 ! regulation of microvillus assembly is_a: GO:0120034 ! positive regulation of plasma membrane bounded cell projection assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030033 ! positively regulates microvillus assembly relationship: RO:0002213 GO:0030033 ! positively regulates microvillus assembly creation_date: 2014-12-03T11:45:17Z [Term] id: GO:1903701 name: substantia propria of cornea development namespace: biological_process def: "The process whose specific outcome is the progression of a substantia propria of cornea over time, from its formation to the mature structure." [GO_REF:0000094, GOC:TermGenie, PMID:12556382] synonym: "corneal stroma development" EXACT [GOC:TermGenie] synonym: "stroma of cornea development" EXACT [GOC:TermGenie] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001777 ! results in development of substantia propria of cornea relationship: RO:0002296 UBERON:0001777 ! results in development of substantia propria of cornea creation_date: 2014-12-03T13:12:09Z [Term] id: GO:1903702 name: esophagus development namespace: biological_process def: "The process whose specific outcome is the progression of an esophagus over time, from its formation to the mature structure." [GO_REF:0000094, GOC:TermGenie, ISBN:0-683-40008-8] synonym: "esophageal development" EXACT [MGI:csmith] synonym: "gullet development" EXACT [GOC:TermGenie] synonym: "oesophagus development" EXACT [GOC:TermGenie] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001043 ! results in development of esophagus relationship: RO:0002296 UBERON:0001043 ! results in development of esophagus creation_date: 2014-12-03T14:41:30Z [Term] id: GO:1903706 name: regulation of hemopoiesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of hemopoiesis." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:20080761] synonym: "regulation of blood cell biosynthesis" EXACT [GOC:TermGenie] synonym: "regulation of blood cell formation" EXACT [GOC:TermGenie] synonym: "regulation of haemopoiesis" EXACT [GOC:TermGenie] synonym: "regulation of hematopoiesis" EXACT [GOC:TermGenie] is_a: GO:0002682 ! regulation of immune system process is_a: GO:0060284 ! regulation of cell development is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030097 ! regulates (processual) hemopoiesis relationship: RO:0002211 GO:0030097 ! regulates (processual) hemopoiesis creation_date: 2014-12-04T15:34:13Z [Term] id: GO:1903707 name: negative regulation of hemopoiesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of hemopoiesis." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:20080761] synonym: "down regulation of blood cell biosynthesis" EXACT [GOC:TermGenie] synonym: "down regulation of blood cell formation" EXACT [GOC:TermGenie] synonym: "down regulation of haemopoiesis" EXACT [GOC:TermGenie] synonym: "down regulation of hematopoiesis" EXACT [GOC:TermGenie] synonym: "down regulation of hemopoiesis" EXACT [GOC:TermGenie] synonym: "down-regulation of blood cell biosynthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of blood cell formation" EXACT [GOC:TermGenie] synonym: "down-regulation of haemopoiesis" EXACT [GOC:TermGenie] synonym: "down-regulation of hematopoiesis" EXACT [GOC:TermGenie] synonym: "down-regulation of hemopoiesis" EXACT [GOC:TermGenie] synonym: "downregulation of blood cell biosynthesis" EXACT [GOC:TermGenie] synonym: "downregulation of blood cell formation" EXACT [GOC:TermGenie] synonym: "downregulation of haemopoiesis" EXACT [GOC:TermGenie] synonym: "downregulation of hematopoiesis" EXACT [GOC:TermGenie] synonym: "downregulation of hemopoiesis" EXACT [GOC:TermGenie] synonym: "negative regulation of blood cell biosynthesis" EXACT [GOC:TermGenie] synonym: "negative regulation of blood cell formation" EXACT [GOC:TermGenie] synonym: "negative regulation of haemopoiesis" EXACT [GOC:TermGenie] synonym: "negative regulation of hematopoiesis" EXACT [GOC:TermGenie] is_a: GO:0002683 ! negative regulation of immune system process is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1903706 ! regulation of hemopoiesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030097 ! negatively regulates hemopoiesis relationship: RO:0002212 GO:0030097 ! negatively regulates hemopoiesis creation_date: 2014-12-04T15:34:21Z [Term] id: GO:1903708 name: positive regulation of hemopoiesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of hemopoiesis." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:20080761] synonym: "positive regulation of blood cell biosynthesis" EXACT [GOC:TermGenie] synonym: "positive regulation of blood cell formation" EXACT [GOC:TermGenie] synonym: "positive regulation of haemopoiesis" EXACT [GOC:TermGenie] synonym: "positive regulation of hematopoiesis" EXACT [GOC:TermGenie] synonym: "up regulation of blood cell biosynthesis" EXACT [GOC:TermGenie] synonym: "up regulation of blood cell formation" EXACT [GOC:TermGenie] synonym: "up regulation of haemopoiesis" EXACT [GOC:TermGenie] synonym: "up regulation of hematopoiesis" EXACT [GOC:TermGenie] synonym: "up regulation of hemopoiesis" EXACT [GOC:TermGenie] synonym: "up-regulation of blood cell biosynthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of blood cell formation" EXACT [GOC:TermGenie] synonym: "up-regulation of haemopoiesis" EXACT [GOC:TermGenie] synonym: "up-regulation of hematopoiesis" EXACT [GOC:TermGenie] synonym: "up-regulation of hemopoiesis" EXACT [GOC:TermGenie] synonym: "upregulation of blood cell biosynthesis" EXACT [GOC:TermGenie] synonym: "upregulation of blood cell formation" EXACT [GOC:TermGenie] synonym: "upregulation of haemopoiesis" EXACT [GOC:TermGenie] synonym: "upregulation of hematopoiesis" EXACT [GOC:TermGenie] synonym: "upregulation of hemopoiesis" EXACT [GOC:TermGenie] is_a: GO:0002684 ! positive regulation of immune system process is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1903706 ! regulation of hemopoiesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030097 ! positively regulates hemopoiesis relationship: RO:0002213 GO:0030097 ! positively regulates hemopoiesis creation_date: 2014-12-04T15:34:30Z [Term] id: GO:1903709 name: uterine gland development namespace: biological_process def: "The process whose specific outcome is the progression of an uterine gland over time, from its formation to the mature structure." [GO_REF:0000094, GOC:TermGenie, PMID:23619340] synonym: "endometrial gland development" EXACT [GOC:TermGenie] synonym: "endometrium gland development" EXACT [GOC:TermGenie] synonym: "uterine glands development" EXACT [GOC:TermGenie] synonym: "uterine glands set development" EXACT [GOC:TermGenie] is_a: GO:0048732 ! gland development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002451 ! results in development of endometrial gland relationship: RO:0002296 UBERON:0002451 ! results in development of endometrial gland creation_date: 2014-12-04T18:57:21Z [Term] id: GO:1903729 name: regulation of plasma membrane organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of plasma membrane organization." [GO_REF:0000058, GOC:TermGenie, PMID:24514900] synonym: "regulation of plasma membrane organisation" EXACT [GOC:TermGenie] is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007009 ! regulates (processual) plasma membrane organization relationship: RO:0002211 GO:0007009 ! regulates (processual) plasma membrane organization creation_date: 2014-12-10T18:59:44Z [Term] id: GO:1903778 name: protein localization to vacuolar membrane namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within a vacuolar membrane." [GO_REF:0000087, GOC:TermGenie, PMID:25378562] synonym: "protein localisation in vacuolar membrane" EXACT [GOC:TermGenie] synonym: "protein localisation to vacuolar membrane" EXACT [GOC:TermGenie] synonym: "protein localization in vacuolar membrane" EXACT [GOC:TermGenie] is_a: GO:0072657 ! protein localization to membrane is_a: GO:0072665 ! protein localization to vacuole intersection_of: GO:0008104 ! protein localization intersection_of: RO:0002339 GO:0005774 ! has target end location vacuolar membrane relationship: RO:0002339 GO:0005774 ! has target end location vacuolar membrane creation_date: 2015-01-07T13:15:54Z [Term] id: GO:1903779 name: regulation of cardiac conduction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac conduction." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rph, GOC:TermGenie, PMID:12967627] is_a: GO:0008016 ! regulation of heart contraction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0061337 ! regulates (processual) cardiac conduction relationship: RO:0002211 GO:0061337 ! regulates (processual) cardiac conduction creation_date: 2015-01-07T13:20:11Z [Term] id: GO:1903780 name: negative regulation of cardiac conduction namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac conduction." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rph, GOC:TermGenie, PMID:12967627] synonym: "down regulation of cardiac conduction" EXACT [GOC:TermGenie] synonym: "down-regulation of cardiac conduction" EXACT [GOC:TermGenie] synonym: "downregulation of cardiac conduction" EXACT [GOC:TermGenie] is_a: GO:0048519 ! negative regulation of biological process is_a: GO:1903779 ! regulation of cardiac conduction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0061337 ! negatively regulates cardiac conduction relationship: RO:0002212 GO:0061337 ! negatively regulates cardiac conduction creation_date: 2015-01-07T13:20:20Z [Term] id: GO:1903781 name: positive regulation of cardiac conduction namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cardiac conduction." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rph, GOC:TermGenie, PMID:12967627] synonym: "up regulation of cardiac conduction" EXACT [GOC:TermGenie] synonym: "up-regulation of cardiac conduction" EXACT [GOC:TermGenie] synonym: "upregulation of cardiac conduction" EXACT [GOC:TermGenie] is_a: GO:0048518 ! positive regulation of biological process is_a: GO:1903779 ! regulation of cardiac conduction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0061337 ! positively regulates cardiac conduction relationship: RO:0002213 GO:0061337 ! positively regulates cardiac conduction creation_date: 2015-01-07T13:20:28Z [Term] id: GO:1903789 name: regulation of amino acid transmembrane transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of amino acid transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:16115814] synonym: "regulation of amino acid membrane transport" EXACT [GOC:TermGenie] is_a: GO:0034762 ! regulation of transmembrane transport is_a: GO:0051955 ! regulation of amino acid transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003333 ! regulates (processual) amino acid transmembrane transport relationship: RO:0002211 GO:0003333 ! regulates (processual) amino acid transmembrane transport creation_date: 2015-01-08T17:42:18Z [Term] id: GO:1903795 name: regulation of inorganic anion transmembrane transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of inorganic anion transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:11336802] synonym: "regulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] synonym: "regulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] is_a: GO:0034762 ! regulation of transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0098661 ! regulates (processual) inorganic anion transmembrane transport relationship: RO:0002211 GO:0098661 ! regulates (processual) inorganic anion transmembrane transport creation_date: 2015-01-14T21:44:49Z [Term] id: GO:1903796 name: negative regulation of inorganic anion transmembrane transport namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of inorganic anion transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:11336802] synonym: "down regulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] synonym: "down regulation of inorganic anion transmembrane transport" EXACT [GOC:TermGenie] synonym: "down regulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] synonym: "down-regulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] synonym: "down-regulation of inorganic anion transmembrane transport" EXACT [GOC:TermGenie] synonym: "down-regulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] synonym: "downregulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] synonym: "downregulation of inorganic anion transmembrane transport" EXACT [GOC:TermGenie] synonym: "downregulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] synonym: "negative regulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] synonym: "negative regulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] is_a: GO:0034763 ! negative regulation of transmembrane transport is_a: GO:1903795 ! regulation of inorganic anion transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0098661 ! negatively regulates inorganic anion transmembrane transport relationship: RO:0002212 GO:0098661 ! negatively regulates inorganic anion transmembrane transport creation_date: 2015-01-14T21:44:59Z [Term] id: GO:1903797 name: positive regulation of inorganic anion transmembrane transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of inorganic anion transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:11336802] synonym: "positive regulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] synonym: "positive regulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] synonym: "up regulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] synonym: "up regulation of inorganic anion transmembrane transport" EXACT [GOC:TermGenie] synonym: "up regulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] synonym: "up-regulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] synonym: "up-regulation of inorganic anion transmembrane transport" EXACT [GOC:TermGenie] synonym: "up-regulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] synonym: "upregulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] synonym: "upregulation of inorganic anion transmembrane transport" EXACT [GOC:TermGenie] synonym: "upregulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] is_a: GO:0034764 ! positive regulation of transmembrane transport is_a: GO:1903795 ! regulation of inorganic anion transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0098661 ! positively regulates inorganic anion transmembrane transport relationship: RO:0002213 GO:0098661 ! positively regulates inorganic anion transmembrane transport creation_date: 2015-01-14T21:45:08Z [Term] id: GO:1903825 name: organic acid transmembrane transport namespace: biological_process def: "The process in which an organic acid is transported across a membrane." [GO_REF:0000069, GOC:TermGenie] is_a: GO:0015849 ! organic acid transport is_a: GO:0055085 ! transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002342 GO:0016020 ! results in transport across membrane intersection_of: RO:0004009 CHEBI:64709 ! has primary input organic acid creation_date: 2015-01-20T10:20:58Z [Term] id: GO:1903828 name: negative regulation of protein localization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of a protein localization." [GO_REF:0000058, GOC:TermGenie, GOC:vw] synonym: "down regulation of cellular protein localisation" EXACT [GOC:TermGenie] synonym: "down regulation of cellular protein localization" EXACT [GOC:TermGenie] synonym: "down-regulation of cellular protein localisation" EXACT [GOC:TermGenie] synonym: "down-regulation of cellular protein localization" EXACT [GOC:TermGenie] synonym: "downregulation of cellular protein localisation" EXACT [GOC:TermGenie] synonym: "downregulation of cellular protein localization" EXACT [GOC:TermGenie] synonym: "negative regulation of cellular protein localisation" EXACT [GOC:TermGenie] synonym: "negative regulation of cellular protein localization" EXACT [] is_a: GO:0032880 ! regulation of protein localization is_a: GO:0048523 ! negative regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0008104 ! negatively regulates protein localization relationship: RO:0002212 GO:0008104 ! negatively regulates protein localization creation_date: 2015-01-20T14:32:24Z [Term] id: GO:1903829 name: positive regulation of protein localization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of a protein localization." [GO_REF:0000058, GOC:TermGenie, GOC:vw] synonym: "positive regulation of cellular protein localisation" EXACT [GOC:TermGenie] synonym: "positive regulation of cellular protein localization" EXACT [] synonym: "up regulation of cellular protein localisation" EXACT [GOC:TermGenie] synonym: "up regulation of cellular protein localization" EXACT [GOC:TermGenie] synonym: "up-regulation of cellular protein localisation" EXACT [GOC:TermGenie] synonym: "up-regulation of cellular protein localization" EXACT [GOC:TermGenie] synonym: "upregulation of cellular protein localisation" EXACT [GOC:TermGenie] synonym: "upregulation of cellular protein localization" EXACT [GOC:TermGenie] is_a: GO:0032880 ! regulation of protein localization is_a: GO:0048522 ! positive regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0008104 ! positively regulates protein localization relationship: RO:0002213 GO:0008104 ! positively regulates protein localization creation_date: 2015-01-20T14:32:33Z [Term] id: GO:1903847 name: regulation of aorta morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of aorta morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22269326] is_a: GO:1905651 ! regulation of artery morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0035909 ! regulates (processual) aorta morphogenesis relationship: RO:0002211 GO:0035909 ! regulates (processual) aorta morphogenesis creation_date: 2015-01-23T14:00:51Z [Term] id: GO:1903848 name: negative regulation of aorta morphogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of aorta morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22269326] synonym: "down regulation of aorta morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of aorta morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of aorta morphogenesis" EXACT [GOC:TermGenie] is_a: GO:1903847 ! regulation of aorta morphogenesis is_a: GO:1905652 ! negative regulation of artery morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0035909 ! negatively regulates aorta morphogenesis relationship: RO:0002212 GO:0035909 ! negatively regulates aorta morphogenesis creation_date: 2015-01-23T14:01:01Z [Term] id: GO:1903849 name: positive regulation of aorta morphogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of aorta morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22269326] synonym: "up regulation of aorta morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of aorta morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of aorta morphogenesis" EXACT [GOC:TermGenie] is_a: GO:1903847 ! regulation of aorta morphogenesis is_a: GO:1905653 ! positive regulation of artery morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0035909 ! positively regulates aorta morphogenesis relationship: RO:0002213 GO:0035909 ! positively regulates aorta morphogenesis creation_date: 2015-01-23T14:01:09Z [Term] id: GO:1903867 name: extraembryonic membrane development namespace: biological_process def: "The process whose specific outcome is the progression of an extraembryonic membrane over time, from its formation to the mature structure." [GO_REF:0000094, GOC:TermGenie, ISBN:0073040584] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005631 ! results in development of extraembryonic membrane relationship: RO:0002296 UBERON:0005631 ! results in development of extraembryonic membrane creation_date: 2015-02-05T00:42:16Z [Term] id: GO:1903903 name: regulation of establishment of T cell polarity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of establishment of T cell polarity." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23575248] synonym: "regulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "regulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] synonym: "regulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "regulation of T cell polarization" EXACT [GOC:TermGenie] synonym: "regulation of T lymphocyte polarization" EXACT [GOC:TermGenie] synonym: "regulation of T-cell polarization" EXACT [GOC:TermGenie] is_a: GO:2000114 ! regulation of establishment of cell polarity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001768 ! regulates (processual) establishment of T cell polarity relationship: RO:0002211 GO:0001768 ! regulates (processual) establishment of T cell polarity creation_date: 2015-02-09T10:50:21Z [Term] id: GO:1903904 name: negative regulation of establishment of T cell polarity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of establishment of T cell polarity." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23575248] synonym: "down regulation of establishment of T cell polarity" EXACT [GOC:TermGenie] synonym: "down regulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "down regulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] synonym: "down regulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "down regulation of T cell polarization" EXACT [GOC:TermGenie] synonym: "down regulation of T lymphocyte polarization" EXACT [GOC:TermGenie] synonym: "down regulation of T-cell polarization" EXACT [GOC:TermGenie] synonym: "down-regulation of establishment of T cell polarity" EXACT [GOC:TermGenie] synonym: "down-regulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "down-regulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] synonym: "down-regulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "down-regulation of T cell polarization" EXACT [GOC:TermGenie] synonym: "down-regulation of T lymphocyte polarization" EXACT [GOC:TermGenie] synonym: "down-regulation of T-cell polarization" EXACT [GOC:TermGenie] synonym: "downregulation of establishment of T cell polarity" EXACT [GOC:TermGenie] synonym: "downregulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "downregulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] synonym: "downregulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "downregulation of T cell polarization" EXACT [GOC:TermGenie] synonym: "downregulation of T lymphocyte polarization" EXACT [GOC:TermGenie] synonym: "downregulation of T-cell polarization" EXACT [GOC:TermGenie] synonym: "negative regulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "negative regulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] synonym: "negative regulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "negative regulation of T cell polarization" EXACT [GOC:TermGenie] synonym: "negative regulation of T lymphocyte polarization" EXACT [GOC:TermGenie] synonym: "negative regulation of T-cell polarization" EXACT [GOC:TermGenie] is_a: GO:0050868 ! negative regulation of T cell activation is_a: GO:1903903 ! regulation of establishment of T cell polarity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001768 ! negatively regulates establishment of T cell polarity relationship: RO:0002212 GO:0001768 ! negatively regulates establishment of T cell polarity creation_date: 2015-02-09T10:50:30Z [Term] id: GO:1903905 name: positive regulation of establishment of T cell polarity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of establishment of T cell polarity." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23575248] synonym: "positive regulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "positive regulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] synonym: "positive regulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "positive regulation of T cell polarization" EXACT [GOC:TermGenie] synonym: "positive regulation of T lymphocyte polarization" EXACT [GOC:TermGenie] synonym: "positive regulation of T-cell polarization" EXACT [GOC:TermGenie] synonym: "up regulation of establishment of T cell polarity" EXACT [GOC:TermGenie] synonym: "up regulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "up regulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] synonym: "up regulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "up regulation of T cell polarization" EXACT [GOC:TermGenie] synonym: "up regulation of T lymphocyte polarization" EXACT [GOC:TermGenie] synonym: "up regulation of T-cell polarization" EXACT [GOC:TermGenie] synonym: "up-regulation of establishment of T cell polarity" EXACT [GOC:TermGenie] synonym: "up-regulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "up-regulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] synonym: "up-regulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "up-regulation of T cell polarization" EXACT [GOC:TermGenie] synonym: "up-regulation of T lymphocyte polarization" EXACT [GOC:TermGenie] synonym: "up-regulation of T-cell polarization" EXACT [GOC:TermGenie] synonym: "upregulation of establishment of T cell polarity" EXACT [GOC:TermGenie] synonym: "upregulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "upregulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] synonym: "upregulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "upregulation of T cell polarization" EXACT [GOC:TermGenie] synonym: "upregulation of T lymphocyte polarization" EXACT [GOC:TermGenie] synonym: "upregulation of T-cell polarization" EXACT [GOC:TermGenie] is_a: GO:0050870 ! positive regulation of T cell activation is_a: GO:1903903 ! regulation of establishment of T cell polarity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001768 ! positively regulates establishment of T cell polarity relationship: RO:0002213 GO:0001768 ! positively regulates establishment of T cell polarity creation_date: 2015-02-09T10:50:40Z [Term] id: GO:1903941 name: negative regulation of respiratory gaseous exchange namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of respiratory gaseous exchange." [GO_REF:0000058, GOC:TermGenie, PMID:22819705] synonym: "down regulation of respiratory gaseous exchange" EXACT [GOC:TermGenie] synonym: "down-regulation of respiratory gaseous exchange" EXACT [GOC:TermGenie] synonym: "downregulation of respiratory gaseous exchange" EXACT [GOC:TermGenie] is_a: GO:0043576 ! regulation of respiratory gaseous exchange is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007585 ! negatively regulates respiratory gaseous exchange by respiratory system relationship: RO:0002212 GO:0007585 ! negatively regulates respiratory gaseous exchange by respiratory system creation_date: 2015-02-17T20:26:24Z [Term] id: GO:1903942 name: positive regulation of respiratory gaseous exchange namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of respiratory gaseous exchange." [GO_REF:0000058, GOC:TermGenie, PMID:22819705] synonym: "up regulation of respiratory gaseous exchange" EXACT [GOC:TermGenie] synonym: "up-regulation of respiratory gaseous exchange" EXACT [GOC:TermGenie] synonym: "upregulation of respiratory gaseous exchange" EXACT [GOC:TermGenie] is_a: GO:0043576 ! regulation of respiratory gaseous exchange is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007585 ! positively regulates respiratory gaseous exchange by respiratory system relationship: RO:0002213 GO:0007585 ! positively regulates respiratory gaseous exchange by respiratory system creation_date: 2015-02-17T20:26:35Z [Term] id: GO:1903943 name: regulation of hepatocyte apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of hepatocyte apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:8649852] is_a: GO:1904035 ! regulation of epithelial cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0097284 ! regulates (processual) hepatocyte apoptotic process relationship: RO:0002211 GO:0097284 ! regulates (processual) hepatocyte apoptotic process creation_date: 2015-02-19T12:54:40Z [Term] id: GO:1903944 name: negative regulation of hepatocyte apoptotic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:8649852] synonym: "down regulation of hepatocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of hepatocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of hepatocyte apoptotic process" EXACT [GOC:TermGenie] is_a: GO:1903943 ! regulation of hepatocyte apoptotic process is_a: GO:1904036 ! negative regulation of epithelial cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0097284 ! negatively regulates hepatocyte apoptotic process relationship: RO:0002212 GO:0097284 ! negatively regulates hepatocyte apoptotic process creation_date: 2015-02-19T12:54:50Z [Term] id: GO:1903945 name: positive regulation of hepatocyte apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of hepatocyte apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:8649852] synonym: "up regulation of hepatocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of hepatocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of hepatocyte apoptotic process" EXACT [GOC:TermGenie] is_a: GO:1903943 ! regulation of hepatocyte apoptotic process is_a: GO:1904037 ! positive regulation of epithelial cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0097284 ! positively regulates hepatocyte apoptotic process relationship: RO:0002213 GO:0097284 ! positively regulates hepatocyte apoptotic process creation_date: 2015-02-19T12:54:59Z [Term] id: GO:1903950 name: negative regulation of AV node cell action potential namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of AV node cell action potential." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:nc, GOC:TermGenie, PMID:25281747] synonym: "down regulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "down regulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "down regulation of AV node cell action potential" EXACT [GOC:TermGenie] synonym: "down-regulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "down-regulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "down-regulation of AV node cell action potential" EXACT [GOC:TermGenie] synonym: "downregulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "downregulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "downregulation of AV node cell action potential" EXACT [GOC:TermGenie] synonym: "negative regulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "negative regulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] is_a: GO:0045759 ! negative regulation of action potential is_a: GO:0098904 ! regulation of AV node cell action potential intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0086016 ! negatively regulates AV node cell action potential relationship: RO:0002212 GO:0086016 ! negatively regulates AV node cell action potential creation_date: 2015-02-20T14:59:41Z [Term] id: GO:1903951 name: positive regulation of AV node cell action potential namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of AV node cell action potential." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:nc, GOC:TermGenie, PMID:25281747] synonym: "positive regulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "positive regulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "up regulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "up regulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "up regulation of AV node cell action potential" EXACT [GOC:TermGenie] synonym: "up-regulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "up-regulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "up-regulation of AV node cell action potential" EXACT [GOC:TermGenie] synonym: "upregulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "upregulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "upregulation of AV node cell action potential" EXACT [GOC:TermGenie] is_a: GO:0045760 ! positive regulation of action potential is_a: GO:0098904 ! regulation of AV node cell action potential intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0086016 ! positively regulates AV node cell action potential relationship: RO:0002213 GO:0086016 ! positively regulates AV node cell action potential creation_date: 2015-02-20T14:59:50Z [Term] id: GO:1903975 name: regulation of glial cell migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of glial cell migration." [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:19100238] synonym: "regulation of glia cell migration" EXACT [GOC:TermGenie] is_a: GO:0030334 ! regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0008347 ! regulates (processual) glial cell migration relationship: RO:0002211 GO:0008347 ! regulates (processual) glial cell migration creation_date: 2015-03-02T15:13:31Z [Term] id: GO:1903976 name: negative regulation of glial cell migration namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of glial cell migration." [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:19100238] synonym: "down regulation of glia cell migration" EXACT [GOC:TermGenie] synonym: "down regulation of glial cell migration" EXACT [GOC:TermGenie] synonym: "down-regulation of glia cell migration" EXACT [GOC:TermGenie] synonym: "down-regulation of glial cell migration" EXACT [GOC:TermGenie] synonym: "downregulation of glia cell migration" EXACT [GOC:TermGenie] synonym: "downregulation of glial cell migration" EXACT [GOC:TermGenie] synonym: "negative regulation of glia cell migration" EXACT [GOC:TermGenie] is_a: GO:0030336 ! negative regulation of cell migration is_a: GO:1903975 ! regulation of glial cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0008347 ! negatively regulates glial cell migration relationship: RO:0002212 GO:0008347 ! negatively regulates glial cell migration creation_date: 2015-03-02T15:13:38Z [Term] id: GO:1903977 name: positive regulation of glial cell migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of glial cell migration." [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:19100238] synonym: "positive regulation of glia cell migration" EXACT [GOC:TermGenie] synonym: "up regulation of glia cell migration" EXACT [GOC:TermGenie] synonym: "up regulation of glial cell migration" EXACT [GOC:TermGenie] synonym: "up-regulation of glia cell migration" EXACT [GOC:TermGenie] synonym: "up-regulation of glial cell migration" EXACT [GOC:TermGenie] synonym: "upregulation of glia cell migration" EXACT [GOC:TermGenie] synonym: "upregulation of glial cell migration" EXACT [GOC:TermGenie] is_a: GO:0030335 ! positive regulation of cell migration is_a: GO:1903975 ! regulation of glial cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0008347 ! positively regulates glial cell migration relationship: RO:0002213 GO:0008347 ! positively regulates glial cell migration creation_date: 2015-03-02T15:13:43Z [Term] id: GO:1904014 name: response to serotonin namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:1505525] is_a: GO:1901698 ! response to nitrogen compound intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:350546 ! has primary input serotonin(1+) relationship: RO:0004009 CHEBI:350546 ! has primary input serotonin(1+) creation_date: 2015-03-06T19:33:54Z [Term] id: GO:1904018 name: positive regulation of vasculature development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of vasculature development." [GO_REF:0000058, GOC:TermGenie, PMID:21472453] synonym: "up regulation of vasculature development" EXACT [GOC:TermGenie] synonym: "up-regulation of vasculature development" EXACT [GOC:TermGenie] synonym: "upregulation of vasculature development" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1901342 ! regulation of vasculature development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001944 ! positively regulates vasculature development relationship: RO:0002213 GO:0001944 ! positively regulates vasculature development creation_date: 2015-03-06T22:17:04Z [Term] id: GO:1904019 name: epithelial cell apoptotic process namespace: biological_process def: "Any apoptotic process in an epithelial cell." [GO_REF:0000085, GOC:TermGenie, PMID:19137015] synonym: "epitheliocyte apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000066 ! occurs in epithelial cell relationship: BFO:0000066 CL:0000066 ! occurs in epithelial cell creation_date: 2015-03-06T22:27:17Z [Term] id: GO:1904026 name: regulation of collagen fibril organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of collagen fibril organization." [GO_REF:0000058, GOC:TermGenie, PMID:25451920] synonym: "regulation of collagen fibril organisation" EXACT [GOC:TermGenie] synonym: "regulation of fibrillar collagen organization" EXACT [GOC:TermGenie] is_a: GO:1902903 ! regulation of supramolecular fiber organization is_a: GO:1903053 ! regulation of extracellular matrix organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030199 ! regulates (processual) collagen fibril organization relationship: RO:0002211 GO:0030199 ! regulates (processual) collagen fibril organization creation_date: 2015-03-12T12:36:52Z [Term] id: GO:1904027 name: negative regulation of collagen fibril organization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of collagen fibril organization." [GO_REF:0000058, GOC:TermGenie, PMID:25451920] synonym: "down regulation of collagen fibril organisation" EXACT [GOC:TermGenie] synonym: "down regulation of collagen fibril organization" EXACT [GOC:TermGenie] synonym: "down regulation of fibrillar collagen organization" EXACT [GOC:TermGenie] synonym: "down-regulation of collagen fibril organisation" EXACT [GOC:TermGenie] synonym: "down-regulation of collagen fibril organization" EXACT [GOC:TermGenie] synonym: "down-regulation of fibrillar collagen organization" EXACT [GOC:TermGenie] synonym: "downregulation of collagen fibril organisation" EXACT [GOC:TermGenie] synonym: "downregulation of collagen fibril organization" EXACT [GOC:TermGenie] synonym: "downregulation of fibrillar collagen organization" EXACT [GOC:TermGenie] synonym: "negative regulation of collagen fibril organisation" EXACT [GOC:TermGenie] synonym: "negative regulation of fibrillar collagen organization" EXACT [GOC:TermGenie] is_a: GO:1902904 ! negative regulation of supramolecular fiber organization is_a: GO:1903054 ! negative regulation of extracellular matrix organization is_a: GO:1904026 ! regulation of collagen fibril organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030199 ! negatively regulates collagen fibril organization relationship: RO:0002212 GO:0030199 ! negatively regulates collagen fibril organization creation_date: 2015-03-12T12:36:59Z [Term] id: GO:1904028 name: positive regulation of collagen fibril organization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of collagen fibril organization." [GO_REF:0000058, GOC:TermGenie, PMID:25451920] synonym: "positive regulation of collagen fibril organisation" EXACT [GOC:TermGenie] synonym: "positive regulation of fibrillar collagen organization" EXACT [GOC:TermGenie] synonym: "up regulation of collagen fibril organisation" EXACT [GOC:TermGenie] synonym: "up regulation of collagen fibril organization" EXACT [GOC:TermGenie] synonym: "up regulation of fibrillar collagen organization" EXACT [GOC:TermGenie] synonym: "up-regulation of collagen fibril organisation" EXACT [GOC:TermGenie] synonym: "up-regulation of collagen fibril organization" EXACT [GOC:TermGenie] synonym: "up-regulation of fibrillar collagen organization" EXACT [GOC:TermGenie] synonym: "upregulation of collagen fibril organisation" EXACT [GOC:TermGenie] synonym: "upregulation of collagen fibril organization" EXACT [GOC:TermGenie] synonym: "upregulation of fibrillar collagen organization" EXACT [GOC:TermGenie] is_a: GO:1902905 ! positive regulation of supramolecular fiber organization is_a: GO:1903055 ! positive regulation of extracellular matrix organization is_a: GO:1904026 ! regulation of collagen fibril organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030199 ! positively regulates collagen fibril organization relationship: RO:0002213 GO:0030199 ! positively regulates collagen fibril organization creation_date: 2015-03-12T12:37:06Z [Term] id: GO:1904035 name: regulation of epithelial cell apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of epithelial cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:19137015] synonym: "regulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1904019 ! regulates (processual) epithelial cell apoptotic process relationship: RO:0002211 GO:1904019 ! regulates (processual) epithelial cell apoptotic process creation_date: 2015-03-13T22:05:41Z [Term] id: GO:1904036 name: negative regulation of epithelial cell apoptotic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:19137015] synonym: "down regulation of epithelial cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down regulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of epithelial cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of epithelial cell apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "negative regulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0043066 ! negative regulation of apoptotic process is_a: GO:1904035 ! regulation of epithelial cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1904019 ! negatively regulates epithelial cell apoptotic process relationship: RO:0002212 GO:1904019 ! negatively regulates epithelial cell apoptotic process creation_date: 2015-03-13T22:05:47Z [Term] id: GO:1904037 name: positive regulation of epithelial cell apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of epithelial cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:19137015] synonym: "positive regulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of epithelial cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of epithelial cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of epithelial cell apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0043065 ! positive regulation of apoptotic process is_a: GO:1904035 ! regulation of epithelial cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1904019 ! positively regulates epithelial cell apoptotic process relationship: RO:0002213 GO:1904019 ! positively regulates epithelial cell apoptotic process creation_date: 2015-03-13T22:05:53Z [Term] id: GO:1904054 name: regulation of cholangiocyte proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cholangiocyte proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24434010] synonym: "regulation of hepatoblast proliferation" EXACT [GOC:TermGenie] is_a: GO:0050678 ! regulation of epithelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1990705 ! regulates (processual) cholangiocyte proliferation relationship: RO:0002211 GO:1990705 ! regulates (processual) cholangiocyte proliferation creation_date: 2015-03-18T17:56:14Z [Term] id: GO:1904055 name: negative regulation of cholangiocyte proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cholangiocyte proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24434010] synonym: "down regulation of cholangiocyte proliferation" EXACT [GOC:TermGenie] synonym: "down regulation of hepatoblast proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of cholangiocyte proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of hepatoblast proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of cholangiocyte proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of hepatoblast proliferation" EXACT [GOC:TermGenie] synonym: "negative regulation of hepatoblast proliferation" EXACT [GOC:TermGenie] is_a: GO:0050680 ! negative regulation of epithelial cell proliferation is_a: GO:1904054 ! regulation of cholangiocyte proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1990705 ! negatively regulates cholangiocyte proliferation relationship: RO:0002212 GO:1990705 ! negatively regulates cholangiocyte proliferation creation_date: 2015-03-18T17:56:20Z [Term] id: GO:1904056 name: positive regulation of cholangiocyte proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cholangiocyte proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24434010] synonym: "positive regulation of hepatoblast proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of cholangiocyte proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of hepatoblast proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of cholangiocyte proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of hepatoblast proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of cholangiocyte proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of hepatoblast proliferation" EXACT [GOC:TermGenie] is_a: GO:0050679 ! positive regulation of epithelial cell proliferation is_a: GO:1904054 ! regulation of cholangiocyte proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1990705 ! positively regulates cholangiocyte proliferation relationship: RO:0002213 GO:1990705 ! positively regulates cholangiocyte proliferation creation_date: 2015-03-18T17:56:26Z [Term] id: GO:1904057 name: negative regulation of sensory perception of pain namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of pain." [GO_REF:0000058, GOC:TermGenie, PMID:17167094] synonym: "down regulation of nociception" EXACT [GOC:TermGenie] synonym: "down regulation of sensory perception of pain" EXACT [GOC:TermGenie] synonym: "down-regulation of nociception" EXACT [GOC:TermGenie] synonym: "down-regulation of sensory perception of pain" EXACT [GOC:TermGenie] synonym: "downregulation of nociception" EXACT [GOC:TermGenie] synonym: "downregulation of sensory perception of pain" EXACT [GOC:TermGenie] synonym: "negative regulation of nociception" EXACT [GOC:TermGenie] is_a: GO:0031645 ! negative regulation of nervous system process is_a: GO:0051930 ! regulation of sensory perception of pain intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0019233 ! negatively regulates sensory perception of pain relationship: RO:0002212 GO:0019233 ! negatively regulates sensory perception of pain creation_date: 2015-03-18T20:33:57Z [Term] id: GO:1904058 name: positive regulation of sensory perception of pain namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of sensory perception of pain." [GO_REF:0000058, GOC:TermGenie, PMID:17167094] synonym: "positive regulation of nociception" EXACT [GOC:TermGenie] synonym: "up regulation of nociception" EXACT [GOC:TermGenie] synonym: "up regulation of sensory perception of pain" EXACT [GOC:TermGenie] synonym: "up-regulation of nociception" EXACT [GOC:TermGenie] synonym: "up-regulation of sensory perception of pain" EXACT [GOC:TermGenie] synonym: "upregulation of nociception" EXACT [GOC:TermGenie] synonym: "upregulation of sensory perception of pain" EXACT [GOC:TermGenie] is_a: GO:0031646 ! positive regulation of nervous system process is_a: GO:0051930 ! regulation of sensory perception of pain intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0019233 ! positively regulates sensory perception of pain relationship: RO:0002213 GO:0019233 ! positively regulates sensory perception of pain creation_date: 2015-03-18T20:34:03Z [Term] id: GO:1904062 name: regulation of monoatomic cation transmembrane transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cation transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:15304482] is_a: GO:0034765 ! regulation of monoatomic ion transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0098655 ! regulates (processual) monoatomic cation transmembrane transport relationship: RO:0002211 GO:0098655 ! regulates (processual) monoatomic cation transmembrane transport creation_date: 2015-03-18T21:11:43Z [Term] id: GO:1904063 name: negative regulation of cation transmembrane transport namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cation transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:15304482] synonym: "down regulation of cation transmembrane transport" EXACT [GOC:TermGenie] synonym: "down-regulation of cation transmembrane transport" EXACT [GOC:TermGenie] synonym: "downregulation of cation transmembrane transport" EXACT [GOC:TermGenie] is_a: GO:0034766 ! negative regulation of monoatomic ion transmembrane transport is_a: GO:1904062 ! regulation of monoatomic cation transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0098655 ! negatively regulates monoatomic cation transmembrane transport relationship: RO:0002212 GO:0098655 ! negatively regulates monoatomic cation transmembrane transport creation_date: 2015-03-18T21:11:50Z [Term] id: GO:1904064 name: positive regulation of cation transmembrane transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cation transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:15304482] synonym: "up regulation of cation transmembrane transport" EXACT [GOC:TermGenie] synonym: "up-regulation of cation transmembrane transport" EXACT [GOC:TermGenie] synonym: "upregulation of cation transmembrane transport" EXACT [GOC:TermGenie] is_a: GO:0034767 ! positive regulation of monoatomic ion transmembrane transport is_a: GO:1904062 ! regulation of monoatomic cation transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0098655 ! positively regulates monoatomic cation transmembrane transport relationship: RO:0002213 GO:0098655 ! positively regulates monoatomic cation transmembrane transport creation_date: 2015-03-18T21:11:55Z [Term] id: GO:1904073 name: regulation of trophectodermal cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of trophectodermal cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24508636] synonym: "regulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0042127 ! regulation of cell population proliferation is_a: GO:0048638 ! regulation of developmental growth intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001834 ! regulates (processual) trophectodermal cell proliferation relationship: RO:0002211 GO:0001834 ! regulates (processual) trophectodermal cell proliferation creation_date: 2015-03-20T16:55:56Z [Term] id: GO:1904074 name: negative regulation of trophectodermal cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of trophectodermal cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24508636] synonym: "down regulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] synonym: "down regulation of trophectodermal cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of trophectodermal cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of trophectodermal cell proliferation" EXACT [GOC:TermGenie] synonym: "negative regulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:1904073 ! regulation of trophectodermal cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001834 ! negatively regulates trophectodermal cell proliferation relationship: RO:0002212 GO:0001834 ! negatively regulates trophectodermal cell proliferation creation_date: 2015-03-20T16:56:02Z [Term] id: GO:1904075 name: positive regulation of trophectodermal cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of trophectodermal cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24508636] synonym: "positive regulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of trophectodermal cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of trophectodermal cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of trophectodermal cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:1904073 ! regulation of trophectodermal cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001834 ! positively regulates trophectodermal cell proliferation relationship: RO:0002213 GO:0001834 ! positively regulates trophectodermal cell proliferation creation_date: 2015-03-20T16:56:08Z [Term] id: GO:1904106 name: protein localization to microvillus namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within a microvillus." [GO_REF:0000087, GOC:kmv, GOC:TermGenie, PMID:25335890] synonym: "protein localisation in microvillus" EXACT [GOC:TermGenie] synonym: "protein localisation to microvillus" EXACT [GOC:TermGenie] synonym: "protein localization in microvillus" EXACT [GOC:TermGenie] is_a: GO:0008104 ! protein localization intersection_of: GO:0008104 ! protein localization intersection_of: RO:0002339 GO:0005902 ! has target end location microvillus relationship: RO:0002339 GO:0005902 ! has target end location microvillus creation_date: 2015-04-01T18:14:41Z [Term] id: GO:1904145 name: negative regulation of meiotic cell cycle process involved in oocyte maturation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation." [GO_REF:0000058, GOC:TermGenie, PMID:22674394] synonym: "down regulation of meiotic cell cycle process involved in oocyte maturation" EXACT [GOC:TermGenie] synonym: "down-regulation of meiotic cell cycle process involved in oocyte maturation" EXACT [GOC:TermGenie] synonym: "downregulation of meiotic cell cycle process involved in oocyte maturation" EXACT [GOC:TermGenie] is_a: GO:0010948 ! negative regulation of cell cycle process is_a: GO:0051447 ! negative regulation of meiotic cell cycle is_a: GO:1900194 ! negative regulation of oocyte maturation is_a: GO:1903538 ! regulation of meiotic cell cycle process involved in oocyte maturation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1903537 ! negatively regulates meiotic cell cycle process involved in oocyte maturation relationship: RO:0002212 GO:1903537 ! negatively regulates meiotic cell cycle process involved in oocyte maturation creation_date: 2015-04-14T15:59:22Z [Term] id: GO:1904146 name: positive regulation of meiotic cell cycle process involved in oocyte maturation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation." [GO_REF:0000058, GOC:TermGenie, PMID:22674394] synonym: "up regulation of meiotic cell cycle process involved in oocyte maturation" EXACT [GOC:TermGenie] synonym: "up-regulation of meiotic cell cycle process involved in oocyte maturation" EXACT [GOC:TermGenie] synonym: "upregulation of meiotic cell cycle process involved in oocyte maturation" EXACT [GOC:TermGenie] is_a: GO:0051446 ! positive regulation of meiotic cell cycle is_a: GO:0090068 ! positive regulation of cell cycle process is_a: GO:1903538 ! regulation of meiotic cell cycle process involved in oocyte maturation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1903537 ! positively regulates meiotic cell cycle process involved in oocyte maturation relationship: RO:0002213 GO:1903537 ! positively regulates meiotic cell cycle process involved in oocyte maturation creation_date: 2015-04-14T15:59:28Z [Term] id: GO:1904170 name: regulation of bleb assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of bleb assembly." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:25651887] synonym: "regulation of cell blebbing" EXACT [GOC:TermGenie] is_a: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0032060 ! regulates (processual) bleb assembly relationship: RO:0002211 GO:0032060 ! regulates (processual) bleb assembly creation_date: 2015-04-23T09:32:19Z [Term] id: GO:1904171 name: negative regulation of bleb assembly namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of bleb assembly." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:25651887] synonym: "down regulation of bleb assembly" EXACT [GOC:TermGenie] synonym: "down regulation of cell blebbing" EXACT [GOC:TermGenie] synonym: "down-regulation of bleb assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of cell blebbing" EXACT [GOC:TermGenie] synonym: "downregulation of bleb assembly" EXACT [GOC:TermGenie] synonym: "downregulation of cell blebbing" EXACT [GOC:TermGenie] synonym: "negative regulation of cell blebbing" EXACT [GOC:TermGenie] is_a: GO:0120033 ! negative regulation of plasma membrane bounded cell projection assembly is_a: GO:1904170 ! regulation of bleb assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0032060 ! negatively regulates bleb assembly relationship: RO:0002212 GO:0032060 ! negatively regulates bleb assembly creation_date: 2015-04-23T09:32:25Z [Term] id: GO:1904172 name: positive regulation of bleb assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of bleb assembly." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:25651887] synonym: "positive regulation of cell blebbing" EXACT [GOC:TermGenie] synonym: "up regulation of bleb assembly" EXACT [GOC:TermGenie] synonym: "up regulation of cell blebbing" EXACT [GOC:TermGenie] synonym: "up-regulation of bleb assembly" EXACT [GOC:TermGenie] synonym: "up-regulation of cell blebbing" EXACT [GOC:TermGenie] synonym: "upregulation of bleb assembly" EXACT [GOC:TermGenie] synonym: "upregulation of cell blebbing" EXACT [GOC:TermGenie] is_a: GO:0120034 ! positive regulation of plasma membrane bounded cell projection assembly is_a: GO:1904170 ! regulation of bleb assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0032060 ! positively regulates bleb assembly relationship: RO:0002213 GO:0032060 ! positively regulates bleb assembly creation_date: 2015-04-23T09:32:31Z [Term] id: GO:1904177 name: regulation of adipose tissue development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of adipose tissue development." [GO_REF:0000058, GOC:TermGenie, PMID:23081848] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060612 ! regulates (processual) adipose tissue development relationship: RO:0002211 GO:0060612 ! regulates (processual) adipose tissue development creation_date: 2015-04-29T20:01:01Z [Term] id: GO:1904178 name: negative regulation of adipose tissue development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of adipose tissue development." [GO_REF:0000058, GOC:TermGenie, PMID:23081848] synonym: "down regulation of adipose tissue development" EXACT [GOC:TermGenie] synonym: "down-regulation of adipose tissue development" EXACT [GOC:TermGenie] synonym: "downregulation of adipose tissue development" EXACT [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1904177 ! regulation of adipose tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060612 ! negatively regulates adipose tissue development relationship: RO:0002212 GO:0060612 ! negatively regulates adipose tissue development creation_date: 2015-04-29T20:01:07Z [Term] id: GO:1904179 name: positive regulation of adipose tissue development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of adipose tissue development." [GO_REF:0000058, GOC:TermGenie, PMID:23081848] synonym: "up regulation of adipose tissue development" EXACT [GOC:TermGenie] synonym: "up-regulation of adipose tissue development" EXACT [GOC:TermGenie] synonym: "upregulation of adipose tissue development" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1904177 ! regulation of adipose tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060612 ! positively regulates adipose tissue development relationship: RO:0002213 GO:0060612 ! positively regulates adipose tissue development creation_date: 2015-04-29T20:01:13Z [Term] id: GO:1904192 name: regulation of cholangiocyte apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cholangiocyte apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:24498161] synonym: "regulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] is_a: GO:1904035 ! regulation of epithelial cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1902488 ! regulates (processual) cholangiocyte apoptotic process relationship: RO:0002211 GO:1902488 ! regulates (processual) cholangiocyte apoptotic process creation_date: 2015-05-06T15:25:48Z [Term] id: GO:1904193 name: negative regulation of cholangiocyte apoptotic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cholangiocyte apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:24498161] synonym: "down regulation of cholangiocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "down regulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of cholangiocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of cholangiocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] synonym: "negative regulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] is_a: GO:1904036 ! negative regulation of epithelial cell apoptotic process is_a: GO:1904192 ! regulation of cholangiocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1902488 ! negatively regulates cholangiocyte apoptotic process relationship: RO:0002212 GO:1902488 ! negatively regulates cholangiocyte apoptotic process creation_date: 2015-05-06T15:25:55Z [Term] id: GO:1904194 name: positive regulation of cholangiocyte apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cholangiocyte apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:24498161] synonym: "positive regulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of cholangiocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of cholangiocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of cholangiocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] is_a: GO:1904037 ! positive regulation of epithelial cell apoptotic process is_a: GO:1904192 ! regulation of cholangiocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1902488 ! positively regulates cholangiocyte apoptotic process relationship: RO:0002213 GO:1902488 ! positively regulates cholangiocyte apoptotic process creation_date: 2015-05-06T15:26:00Z [Term] id: GO:1904204 name: regulation of skeletal muscle hypertrophy namespace: biological_process def: "Any process that modulates the frequency, rate or extent of skeletal muscle hypertrophy." [GO_REF:0000058, GOC:TermGenie, PMID:23470307] is_a: GO:0014733 ! regulation of skeletal muscle adaptation is_a: GO:0014743 ! regulation of muscle hypertrophy intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0014734 ! regulates (processual) skeletal muscle hypertrophy relationship: RO:0002211 GO:0014734 ! regulates (processual) skeletal muscle hypertrophy creation_date: 2015-05-08T17:38:13Z [Term] id: GO:1904205 name: negative regulation of skeletal muscle hypertrophy namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle hypertrophy." [GO_REF:0000058, GOC:TermGenie, PMID:23470307] synonym: "down regulation of skeletal muscle hypertrophy" EXACT [GOC:TermGenie] synonym: "down-regulation of skeletal muscle hypertrophy" EXACT [GOC:TermGenie] synonym: "downregulation of skeletal muscle hypertrophy" EXACT [GOC:TermGenie] is_a: GO:0014741 ! negative regulation of muscle hypertrophy is_a: GO:0014745 ! negative regulation of muscle adaptation is_a: GO:1904204 ! regulation of skeletal muscle hypertrophy intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0014734 ! negatively regulates skeletal muscle hypertrophy relationship: RO:0002212 GO:0014734 ! negatively regulates skeletal muscle hypertrophy creation_date: 2015-05-08T17:38:19Z [Term] id: GO:1904206 name: positive regulation of skeletal muscle hypertrophy namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of skeletal muscle hypertrophy." [GO_REF:0000058, GOC:TermGenie, PMID:23470307] synonym: "up regulation of skeletal muscle hypertrophy" EXACT [GOC:TermGenie] synonym: "up-regulation of skeletal muscle hypertrophy" EXACT [GOC:TermGenie] synonym: "upregulation of skeletal muscle hypertrophy" EXACT [GOC:TermGenie] is_a: GO:0014742 ! positive regulation of muscle hypertrophy is_a: GO:0014744 ! positive regulation of muscle adaptation is_a: GO:1904204 ! regulation of skeletal muscle hypertrophy intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0014734 ! positively regulates skeletal muscle hypertrophy relationship: RO:0002213 GO:0014734 ! positively regulates skeletal muscle hypertrophy creation_date: 2015-05-08T17:38:25Z [Term] id: GO:1904251 name: regulation of bile acid metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of bile acid metabolic process." [GO_REF:0000058, GOC:bf, GOC:TermGenie] synonym: "regulation of bile acid metabolism" EXACT [GOC:TermGenie] is_a: GO:0019218 ! regulation of steroid metabolic process is_a: GO:0031323 ! regulation of cellular metabolic process is_a: GO:0062012 ! regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0008206 ! regulates (processual) bile acid metabolic process relationship: RO:0002211 GO:0008206 ! regulates (processual) bile acid metabolic process creation_date: 2015-05-20T11:04:28Z [Term] id: GO:1904252 name: negative regulation of bile acid metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of bile acid metabolic process." [GO_REF:0000058, GOC:bf, GOC:TermGenie] synonym: "down regulation of bile acid metabolic process" EXACT [GOC:TermGenie] synonym: "down regulation of bile acid metabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of bile acid metabolic process" EXACT [GOC:TermGenie] synonym: "down-regulation of bile acid metabolism" EXACT [GOC:TermGenie] synonym: "downregulation of bile acid metabolic process" EXACT [GOC:TermGenie] synonym: "downregulation of bile acid metabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of bile acid metabolism" EXACT [GOC:TermGenie] is_a: GO:0031324 ! negative regulation of cellular metabolic process is_a: GO:0045939 ! negative regulation of steroid metabolic process is_a: GO:0062014 ! negative regulation of small molecule metabolic process is_a: GO:1904251 ! regulation of bile acid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0008206 ! negatively regulates bile acid metabolic process relationship: RO:0002212 GO:0008206 ! negatively regulates bile acid metabolic process creation_date: 2015-05-20T11:04:35Z [Term] id: GO:1904253 name: positive regulation of bile acid metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of bile acid metabolic process." [GO_REF:0000058, GOC:bf, GOC:TermGenie] synonym: "positive regulation of bile acid metabolism" EXACT [GOC:TermGenie] synonym: "up regulation of bile acid metabolic process" EXACT [GOC:TermGenie] synonym: "up regulation of bile acid metabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of bile acid metabolic process" EXACT [GOC:TermGenie] synonym: "up-regulation of bile acid metabolism" EXACT [GOC:TermGenie] synonym: "upregulation of bile acid metabolic process" EXACT [GOC:TermGenie] synonym: "upregulation of bile acid metabolism" EXACT [GOC:TermGenie] is_a: GO:0031325 ! positive regulation of cellular metabolic process is_a: GO:0045940 ! positive regulation of steroid metabolic process is_a: GO:0062013 ! positive regulation of small molecule metabolic process is_a: GO:1904251 ! regulation of bile acid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0008206 ! positively regulates bile acid metabolic process relationship: RO:0002213 GO:0008206 ! positively regulates bile acid metabolic process creation_date: 2015-05-20T11:04:40Z [Term] id: GO:1904269 name: cell leading edge cell cortex namespace: cellular_component def: "The cell cortex of the leading edge of a cell." [GO_REF:0000064, GOC:kmv, GOC:TermGenie, PMID:25843030] synonym: "cell cortex of cell leading edge" EXACT [GOC:TermGenie] synonym: "cell cortex of front of cell" EXACT [GOC:TermGenie] synonym: "cell cortex of leading edge of cell" EXACT [GOC:TermGenie] is_a: GO:0099738 ! cell cortex region intersection_of: GO:0099738 ! cell cortex region intersection_of: BFO:0000050 GO:0031252 ! part of cell leading edge relationship: BFO:0000050 GO:0031252 ! part of cell leading edge creation_date: 2015-05-28T19:16:03Z [Term] id: GO:1904304 name: regulation of gastro-intestinal system smooth muscle contraction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of gastro-intestinal system smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:10821044] is_a: GO:0006940 ! regulation of smooth muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0014831 ! regulates (processual) gastro-intestinal system smooth muscle contraction relationship: RO:0002211 GO:0014831 ! regulates (processual) gastro-intestinal system smooth muscle contraction creation_date: 2015-06-09T23:18:42Z [Term] id: GO:1904305 name: negative regulation of gastro-intestinal system smooth muscle contraction namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of gastro-intestinal system smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:10821044] synonym: "down regulation of gastro-intestinal system smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "down-regulation of gastro-intestinal system smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "downregulation of gastro-intestinal system smooth muscle contraction" EXACT [GOC:TermGenie] is_a: GO:0045986 ! negative regulation of smooth muscle contraction is_a: GO:1904304 ! regulation of gastro-intestinal system smooth muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0014831 ! negatively regulates gastro-intestinal system smooth muscle contraction relationship: RO:0002212 GO:0014831 ! negatively regulates gastro-intestinal system smooth muscle contraction creation_date: 2015-06-09T23:18:48Z [Term] id: GO:1904306 name: positive regulation of gastro-intestinal system smooth muscle contraction namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of gastro-intestinal system smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:10821044] synonym: "up regulation of gastro-intestinal system smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "up-regulation of gastro-intestinal system smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "upregulation of gastro-intestinal system smooth muscle contraction" EXACT [GOC:TermGenie] is_a: GO:0045987 ! positive regulation of smooth muscle contraction is_a: GO:1904304 ! regulation of gastro-intestinal system smooth muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0014831 ! positively regulates gastro-intestinal system smooth muscle contraction relationship: RO:0002213 GO:0014831 ! positively regulates gastro-intestinal system smooth muscle contraction creation_date: 2015-06-09T23:18:54Z [Term] id: GO:1904318 name: regulation of smooth muscle contraction involved in micturition namespace: biological_process def: "Any process that modulates the frequency, rate or extent of smooth muscle contraction involved in micturition." [GO_REF:0000058, GOC:TermGenie, PMID:18562635] is_a: GO:0006940 ! regulation of smooth muscle contraction is_a: GO:0044062 ! regulation of excretion is_a: GO:0098801 ! regulation of renal system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060083 ! regulates (processual) smooth muscle contraction involved in micturition relationship: RO:0002211 GO:0060083 ! regulates (processual) smooth muscle contraction involved in micturition creation_date: 2015-06-10T18:46:11Z [Term] id: GO:1904319 name: negative regulation of smooth muscle contraction involved in micturition namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle contraction involved in micturition." [GO_REF:0000058, GOC:TermGenie, PMID:18562635] synonym: "down regulation of smooth muscle contraction involved in micturition" EXACT [GOC:TermGenie] synonym: "down-regulation of smooth muscle contraction involved in micturition" EXACT [GOC:TermGenie] synonym: "downregulation of smooth muscle contraction involved in micturition" EXACT [GOC:TermGenie] is_a: GO:0045986 ! negative regulation of smooth muscle contraction is_a: GO:1904318 ! regulation of smooth muscle contraction involved in micturition intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060083 ! negatively regulates smooth muscle contraction involved in micturition relationship: RO:0002212 GO:0060083 ! negatively regulates smooth muscle contraction involved in micturition creation_date: 2015-06-10T18:46:17Z [Term] id: GO:1904320 name: positive regulation of smooth muscle contraction involved in micturition namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of smooth muscle contraction involved in micturition." [GO_REF:0000058, GOC:TermGenie, PMID:18562635] synonym: "up regulation of smooth muscle contraction involved in micturition" EXACT [GOC:TermGenie] synonym: "up-regulation of smooth muscle contraction involved in micturition" EXACT [GOC:TermGenie] synonym: "upregulation of smooth muscle contraction involved in micturition" EXACT [GOC:TermGenie] is_a: GO:0045987 ! positive regulation of smooth muscle contraction is_a: GO:1904318 ! regulation of smooth muscle contraction involved in micturition intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060083 ! positively regulates smooth muscle contraction involved in micturition relationship: RO:0002213 GO:0060083 ! positively regulates smooth muscle contraction involved in micturition creation_date: 2015-06-10T18:46:23Z [Term] id: GO:1904341 name: regulation of colon smooth muscle contraction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of colon smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:24170253] is_a: GO:1904304 ! regulation of gastro-intestinal system smooth muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1990765 ! regulates (processual) colon smooth muscle contraction relationship: RO:0002211 GO:1990765 ! regulates (processual) colon smooth muscle contraction creation_date: 2015-06-11T21:16:58Z [Term] id: GO:1904342 name: negative regulation of colon smooth muscle contraction namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of colon smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:24170253] synonym: "down regulation of colon smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "down-regulation of colon smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "downregulation of colon smooth muscle contraction" EXACT [GOC:TermGenie] is_a: GO:1904305 ! negative regulation of gastro-intestinal system smooth muscle contraction is_a: GO:1904341 ! regulation of colon smooth muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1990765 ! negatively regulates colon smooth muscle contraction relationship: RO:0002212 GO:1990765 ! negatively regulates colon smooth muscle contraction creation_date: 2015-06-11T21:17:05Z [Term] id: GO:1904343 name: positive regulation of colon smooth muscle contraction namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of colon smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:24170253] synonym: "up regulation of colon smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "up-regulation of colon smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "upregulation of colon smooth muscle contraction" EXACT [GOC:TermGenie] is_a: GO:1904306 ! positive regulation of gastro-intestinal system smooth muscle contraction is_a: GO:1904341 ! regulation of colon smooth muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1990765 ! positively regulates colon smooth muscle contraction relationship: RO:0002213 GO:1990765 ! positively regulates colon smooth muscle contraction creation_date: 2015-06-11T21:17:11Z [Term] id: GO:1904344 name: regulation of gastric mucosal blood circulation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of gastric mucosal blood circulation." [GO_REF:0000058, GOC:TermGenie, PMID:10807413] synonym: "regulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] is_a: GO:1903522 ! regulation of blood circulation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1990768 ! regulates (processual) gastric mucosal blood circulation relationship: RO:0002211 GO:1990768 ! regulates (processual) gastric mucosal blood circulation creation_date: 2015-06-11T21:20:31Z [Term] id: GO:1904345 name: negative regulation of gastric mucosal blood circulation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of gastric mucosal blood circulation." [GO_REF:0000058, GOC:TermGenie, PMID:10807413] synonym: "down regulation of gastric mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "down regulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "down-regulation of gastric mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "down-regulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "downregulation of gastric mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "downregulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "negative regulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] is_a: GO:1903523 ! negative regulation of blood circulation is_a: GO:1904344 ! regulation of gastric mucosal blood circulation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1990768 ! negatively regulates gastric mucosal blood circulation relationship: RO:0002212 GO:1990768 ! negatively regulates gastric mucosal blood circulation creation_date: 2015-06-11T21:20:44Z [Term] id: GO:1904346 name: positive regulation of gastric mucosal blood circulation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of gastric mucosal blood circulation." [GO_REF:0000058, GOC:TermGenie, PMID:10807413] synonym: "positive regulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "up regulation of gastric mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "up regulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "up-regulation of gastric mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "up-regulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "upregulation of gastric mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "upregulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] is_a: GO:1903524 ! positive regulation of blood circulation is_a: GO:1904344 ! regulation of gastric mucosal blood circulation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1990768 ! positively regulates gastric mucosal blood circulation relationship: RO:0002213 GO:1990768 ! positively regulates gastric mucosal blood circulation creation_date: 2015-06-11T21:20:50Z [Term] id: GO:1904347 name: regulation of small intestine smooth muscle contraction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of small intestine smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:11991626] is_a: GO:1904304 ! regulation of gastro-intestinal system smooth muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1990770 ! regulates (processual) small intestine smooth muscle contraction relationship: RO:0002211 GO:1990770 ! regulates (processual) small intestine smooth muscle contraction creation_date: 2015-06-11T21:37:34Z [Term] id: GO:1904348 name: negative regulation of small intestine smooth muscle contraction namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of small intestine smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:11991626] synonym: "down regulation of small intestine smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "down-regulation of small intestine smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "downregulation of small intestine smooth muscle contraction" EXACT [GOC:TermGenie] is_a: GO:1904305 ! negative regulation of gastro-intestinal system smooth muscle contraction is_a: GO:1904347 ! regulation of small intestine smooth muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1990770 ! negatively regulates small intestine smooth muscle contraction relationship: RO:0002212 GO:1990770 ! negatively regulates small intestine smooth muscle contraction creation_date: 2015-06-11T21:37:40Z [Term] id: GO:1904349 name: positive regulation of small intestine smooth muscle contraction namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of small intestine smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:11991626] synonym: "up regulation of small intestine smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "up-regulation of small intestine smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "upregulation of small intestine smooth muscle contraction" EXACT [GOC:TermGenie] is_a: GO:1904306 ! positive regulation of gastro-intestinal system smooth muscle contraction is_a: GO:1904347 ! regulation of small intestine smooth muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1990770 ! positively regulates small intestine smooth muscle contraction relationship: RO:0002213 GO:1990770 ! positively regulates small intestine smooth muscle contraction creation_date: 2015-06-11T21:37:46Z [Term] id: GO:1904350 name: regulation of protein catabolic process in the vacuole namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein catabolic process in the vacuole." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:25635054] is_a: GO:0042176 ! regulation of protein catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007039 ! regulates (processual) protein catabolic process in the vacuole relationship: RO:0002211 GO:0007039 ! regulates (processual) protein catabolic process in the vacuole creation_date: 2015-06-12T09:10:36Z [Term] id: GO:1904351 name: negative regulation of protein catabolic process in the vacuole namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process in the vacuole." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:25635054] synonym: "down regulation of protein catabolic process in the vacuole" EXACT [GOC:TermGenie] synonym: "down-regulation of protein catabolic process in the vacuole" EXACT [GOC:TermGenie] synonym: "downregulation of protein catabolic process in the vacuole" EXACT [GOC:TermGenie] is_a: GO:0042177 ! negative regulation of protein catabolic process is_a: GO:1904350 ! regulation of protein catabolic process in the vacuole intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007039 ! negatively regulates protein catabolic process in the vacuole relationship: RO:0002212 GO:0007039 ! negatively regulates protein catabolic process in the vacuole creation_date: 2015-06-12T09:10:42Z [Term] id: GO:1904352 name: positive regulation of protein catabolic process in the vacuole namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein catabolic process in the vacuole." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:25635054] synonym: "up regulation of protein catabolic process in the vacuole" EXACT [GOC:TermGenie] synonym: "up-regulation of protein catabolic process in the vacuole" EXACT [GOC:TermGenie] synonym: "upregulation of protein catabolic process in the vacuole" EXACT [GOC:TermGenie] is_a: GO:0045732 ! positive regulation of protein catabolic process is_a: GO:1904350 ! regulation of protein catabolic process in the vacuole intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007039 ! positively regulates protein catabolic process in the vacuole relationship: RO:0002213 GO:0007039 ! positively regulates protein catabolic process in the vacuole creation_date: 2015-06-12T09:10:49Z [Term] id: GO:1904375 name: regulation of protein localization to cell periphery namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein localization to cell periphery." [GO_REF:0000058, GOC:TermGenie, PMID:18216290] is_a: GO:0032880 ! regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1990778 ! regulates (processual) protein localization to cell periphery relationship: RO:0002211 GO:1990778 ! regulates (processual) protein localization to cell periphery creation_date: 2015-06-22T22:09:25Z [Term] id: GO:1904376 name: negative regulation of protein localization to cell periphery namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell periphery." [GO_REF:0000058, GOC:TermGenie, PMID:18216290] synonym: "down regulation of protein localization to cell periphery" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to cell periphery" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to cell periphery" EXACT [GOC:TermGenie] is_a: GO:1903828 ! negative regulation of protein localization is_a: GO:1904375 ! regulation of protein localization to cell periphery intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1990778 ! negatively regulates protein localization to cell periphery relationship: RO:0002212 GO:1990778 ! negatively regulates protein localization to cell periphery creation_date: 2015-06-22T22:09:32Z [Term] id: GO:1904377 name: positive regulation of protein localization to cell periphery namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein localization to cell periphery." [GO_REF:0000058, GOC:TermGenie, PMID:18216290] synonym: "up regulation of protein localization to cell periphery" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to cell periphery" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to cell periphery" EXACT [GOC:TermGenie] is_a: GO:1903829 ! positive regulation of protein localization is_a: GO:1904375 ! regulation of protein localization to cell periphery intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1990778 ! positively regulates protein localization to cell periphery relationship: RO:0002213 GO:1990778 ! positively regulates protein localization to cell periphery creation_date: 2015-06-22T22:09:37Z [Term] id: GO:1904396 name: regulation of neuromuscular junction development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of neuromuscular junction development." [GO_REF:0000058, GOC:TermGenie, PMID:7722643] synonym: "regulation of neuromuscular junction organization" EXACT [GOC:TermGenie] is_a: GO:0050807 ! regulation of synapse organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007528 ! regulates (processual) neuromuscular junction development relationship: RO:0002211 GO:0007528 ! regulates (processual) neuromuscular junction development creation_date: 2015-06-23T19:23:42Z [Term] id: GO:1904397 name: negative regulation of neuromuscular junction development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular junction development." [GO_REF:0000058, GOC:TermGenie, PMID:7722643] synonym: "down regulation of neuromuscular junction development" EXACT [GOC:TermGenie] synonym: "down regulation of neuromuscular junction organization" EXACT [GOC:TermGenie] synonym: "down-regulation of neuromuscular junction development" EXACT [GOC:TermGenie] synonym: "down-regulation of neuromuscular junction organization" EXACT [GOC:TermGenie] synonym: "downregulation of neuromuscular junction development" EXACT [GOC:TermGenie] synonym: "downregulation of neuromuscular junction organization" EXACT [GOC:TermGenie] synonym: "negative regulation of neuromuscular junction organization" EXACT [GOC:TermGenie] is_a: GO:1904396 ! regulation of neuromuscular junction development is_a: GO:1905809 ! negative regulation of synapse organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007528 ! negatively regulates neuromuscular junction development relationship: RO:0002212 GO:0007528 ! negatively regulates neuromuscular junction development creation_date: 2015-06-23T19:23:48Z [Term] id: GO:1904398 name: positive regulation of neuromuscular junction development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of neuromuscular junction development." [GO_REF:0000058, GOC:TermGenie, PMID:7722643] synonym: "positive regulation of neuromuscular junction organization" EXACT [GOC:TermGenie] synonym: "up regulation of neuromuscular junction development" EXACT [GOC:TermGenie] synonym: "up regulation of neuromuscular junction organization" EXACT [GOC:TermGenie] synonym: "up-regulation of neuromuscular junction development" EXACT [GOC:TermGenie] synonym: "up-regulation of neuromuscular junction organization" EXACT [GOC:TermGenie] synonym: "upregulation of neuromuscular junction development" EXACT [GOC:TermGenie] synonym: "upregulation of neuromuscular junction organization" EXACT [GOC:TermGenie] is_a: GO:0051130 ! positive regulation of cellular component organization is_a: GO:1904396 ! regulation of neuromuscular junction development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007528 ! positively regulates neuromuscular junction development relationship: RO:0002213 GO:0007528 ! positively regulates neuromuscular junction development creation_date: 2015-06-23T19:23:54Z [Term] id: GO:1904409 name: regulation of secretory granule organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of secretory granule organization." [GO_REF:0000058, GOC:TermGenie, PMID:15039777] synonym: "regulation of secretory granule organisation" EXACT [GOC:TermGenie] is_a: GO:0033043 ! regulation of organelle organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0033363 ! regulates (processual) secretory granule organization relationship: RO:0002211 GO:0033363 ! regulates (processual) secretory granule organization creation_date: 2015-06-25T19:40:42Z [Term] id: GO:1904410 name: negative regulation of secretory granule organization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of secretory granule organization." [GO_REF:0000058, GOC:TermGenie, PMID:15039777] synonym: "down regulation of secretory granule organisation" EXACT [GOC:TermGenie] synonym: "down regulation of secretory granule organization" EXACT [GOC:TermGenie] synonym: "down-regulation of secretory granule organisation" EXACT [GOC:TermGenie] synonym: "down-regulation of secretory granule organization" EXACT [GOC:TermGenie] synonym: "downregulation of secretory granule organisation" EXACT [GOC:TermGenie] synonym: "downregulation of secretory granule organization" EXACT [GOC:TermGenie] synonym: "negative regulation of secretory granule organisation" EXACT [GOC:TermGenie] is_a: GO:0010639 ! negative regulation of organelle organization is_a: GO:1904409 ! regulation of secretory granule organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0033363 ! negatively regulates secretory granule organization relationship: RO:0002212 GO:0033363 ! negatively regulates secretory granule organization creation_date: 2015-06-25T19:40:49Z [Term] id: GO:1904411 name: positive regulation of secretory granule organization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of secretory granule organization." [GO_REF:0000058, GOC:TermGenie, PMID:15039777] synonym: "positive regulation of secretory granule organisation" EXACT [GOC:TermGenie] synonym: "up regulation of secretory granule organisation" EXACT [GOC:TermGenie] synonym: "up regulation of secretory granule organization" EXACT [GOC:TermGenie] synonym: "up-regulation of secretory granule organisation" EXACT [GOC:TermGenie] synonym: "up-regulation of secretory granule organization" EXACT [GOC:TermGenie] synonym: "upregulation of secretory granule organisation" EXACT [GOC:TermGenie] synonym: "upregulation of secretory granule organization" EXACT [GOC:TermGenie] is_a: GO:0010638 ! positive regulation of organelle organization is_a: GO:1904409 ! regulation of secretory granule organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0033363 ! positively regulates secretory granule organization relationship: RO:0002213 GO:0033363 ! positively regulates secretory granule organization creation_date: 2015-06-25T19:40:55Z [Term] id: GO:1904412 name: regulation of cardiac ventricle development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac ventricle development." [GO_REF:0000058, GOC:TermGenie, PMID:19590510] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003231 ! regulates (processual) cardiac ventricle development relationship: RO:0002211 GO:0003231 ! regulates (processual) cardiac ventricle development creation_date: 2015-06-25T19:52:15Z [Term] id: GO:1904413 name: negative regulation of cardiac ventricle development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle development." [GO_REF:0000058, GOC:TermGenie, PMID:19590510] synonym: "down regulation of cardiac ventricle development" EXACT [GOC:TermGenie] synonym: "down-regulation of cardiac ventricle development" EXACT [GOC:TermGenie] synonym: "downregulation of cardiac ventricle development" EXACT [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1904412 ! regulation of cardiac ventricle development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0003231 ! negatively regulates cardiac ventricle development relationship: RO:0002212 GO:0003231 ! negatively regulates cardiac ventricle development creation_date: 2015-06-25T19:52:21Z [Term] id: GO:1904414 name: positive regulation of cardiac ventricle development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cardiac ventricle development." [GO_REF:0000058, GOC:TermGenie, PMID:19590510] synonym: "up regulation of cardiac ventricle development" EXACT [GOC:TermGenie] synonym: "up-regulation of cardiac ventricle development" EXACT [GOC:TermGenie] synonym: "upregulation of cardiac ventricle development" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1904412 ! regulation of cardiac ventricle development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0003231 ! positively regulates cardiac ventricle development relationship: RO:0002213 GO:0003231 ! positively regulates cardiac ventricle development creation_date: 2015-06-25T19:52:27Z [Term] id: GO:1904456 name: negative regulation of neuronal action potential namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of neuronal action potential." [GO_REF:0000058, GOC:TermGenie, PMID:25126967] synonym: "down regulation of neuronal action potential" EXACT [GOC:TermGenie] synonym: "down-regulation of neuronal action potential" EXACT [GOC:TermGenie] synonym: "downregulation of neuronal action potential" EXACT [GOC:TermGenie] is_a: GO:0045759 ! negative regulation of action potential is_a: GO:0051970 ! negative regulation of transmission of nerve impulse is_a: GO:0098908 ! regulation of neuronal action potential intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0019228 ! negatively regulates neuronal action potential relationship: RO:0002212 GO:0019228 ! negatively regulates neuronal action potential creation_date: 2015-07-09T18:02:40Z [Term] id: GO:1904457 name: positive regulation of neuronal action potential namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of neuronal action potential." [GO_REF:0000058, GOC:TermGenie, PMID:25126967] synonym: "up regulation of neuronal action potential" EXACT [GOC:TermGenie] synonym: "up-regulation of neuronal action potential" EXACT [GOC:TermGenie] synonym: "upregulation of neuronal action potential" EXACT [GOC:TermGenie] is_a: GO:0045760 ! positive regulation of action potential is_a: GO:0051971 ! positive regulation of transmission of nerve impulse is_a: GO:0098908 ! regulation of neuronal action potential intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0019228 ! positively regulates neuronal action potential relationship: RO:0002213 GO:0019228 ! positively regulates neuronal action potential creation_date: 2015-07-09T18:02:46Z [Term] id: GO:1904484 name: cloacal gland development namespace: biological_process def: "The process whose specific outcome is the progression of a cloacal gland over time, from its formation to the mature structure." [GO_REF:0000094, GOC:mr, GOC:TermGenie, PMID:18805421] is_a: GO:0048732 ! gland development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0012478 ! results in development of cloacal gland relationship: RO:0002296 UBERON:0012478 ! results in development of cloacal gland creation_date: 2015-07-15T22:14:39Z [Term] id: GO:1904491 name: protein localization to ciliary transition zone namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within a ciliary transition zone." [GO_REF:0000087, GOC:kmv, GOC:TermGenie, PMID:21422230] synonym: "protein localisation in ciliary transition zone" EXACT [GOC:TermGenie] synonym: "protein localisation to ciliary transition zone" EXACT [GOC:TermGenie] synonym: "protein localization in ciliary transition zone" EXACT [GOC:TermGenie] is_a: GO:0061512 ! protein localization to cilium intersection_of: GO:0008104 ! protein localization intersection_of: RO:0002339 GO:0035869 ! has target end location ciliary transition zone relationship: RO:0002339 GO:0035869 ! has target end location ciliary transition zone creation_date: 2015-07-17T20:43:21Z [Term] id: GO:1904587 name: response to glycoprotein namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:14597422] synonym: "response to glycoproteins" EXACT [] is_a: GO:0010033 ! response to organic substance is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:17089 ! has primary input glycoprotein relationship: RO:0004009 CHEBI:17089 ! has primary input glycoprotein creation_date: 2015-08-20T16:46:24Z [Term] id: GO:1904606 name: fat cell apoptotic process namespace: biological_process def: "Any apoptotic process in a fat cell." [GO_REF:0000085, GOC:TermGenie, PMID:17024416] synonym: "adipocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "adipose cell apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000136 ! occurs in adipocyte relationship: BFO:0000066 CL:0000136 ! occurs in adipocyte creation_date: 2015-08-27T18:13:06Z [Term] id: GO:1904649 name: regulation of fat cell apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of fat cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:17024416] synonym: "regulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "regulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1904606 ! regulates (processual) fat cell apoptotic process relationship: RO:0002211 GO:1904606 ! regulates (processual) fat cell apoptotic process creation_date: 2015-08-31T20:59:28Z [Term] id: GO:1904650 name: negative regulation of fat cell apoptotic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of fat cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:17024416] synonym: "down regulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "down regulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down regulation of fat cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of fat cell apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of fat cell apoptotic process" EXACT [GOC:TermGenie] synonym: "negative regulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "negative regulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0043066 ! negative regulation of apoptotic process is_a: GO:1904649 ! regulation of fat cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1904606 ! negatively regulates fat cell apoptotic process relationship: RO:0002212 GO:1904606 ! negatively regulates fat cell apoptotic process creation_date: 2015-08-31T20:59:34Z [Term] id: GO:1904651 name: positive regulation of fat cell apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of fat cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:17024416] synonym: "positive regulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "positive regulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of fat cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of fat cell apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of fat cell apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0043065 ! positive regulation of apoptotic process is_a: GO:1904649 ! regulation of fat cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1904606 ! positively regulates fat cell apoptotic process relationship: RO:0002213 GO:1904606 ! positively regulates fat cell apoptotic process creation_date: 2015-08-31T20:59:40Z [Term] id: GO:1904659 name: glucose transmembrane transport namespace: biological_process def: "The process in which glucose is transported across a membrane." [GO_REF:0000069, GOC:TermGenie, PMID:9090050] is_a: GO:0008645 ! hexose transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002342 GO:0016020 ! results in transport across membrane intersection_of: RO:0004009 CHEBI:17234 ! has primary input glucose relationship: RO:0004009 CHEBI:17234 ! has primary input glucose creation_date: 2015-09-04T17:20:16Z [Term] id: GO:1904671 name: negative regulation of cell differentiation involved in stem cell population maintenance namespace: biological_process def: "Any negative regulation of cell differentiation that is involved in stem cell population maintenance." [GO_REF:0000060, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607] synonym: "down regulation of cell differentiation involved in stem cell population maintenance" EXACT [GOC:TermGenie] synonym: "down-regulation of cell differentiation involved in stem cell population maintenance" EXACT [GOC:TermGenie] synonym: "downregulation of cell differentiation involved in stem cell population maintenance" EXACT [GOC:TermGenie] is_a: GO:0045596 ! negative regulation of cell differentiation intersection_of: GO:0045596 ! negative regulation of cell differentiation intersection_of: BFO:0000050 GO:0019827 ! part of stem cell population maintenance relationship: BFO:0000050 GO:0019827 ! part of stem cell population maintenance creation_date: 2015-09-12T00:46:08Z [Term] id: GO:1904672 name: regulation of somatic stem cell population maintenance namespace: biological_process def: "Any process that modulates the frequency, rate or extent of somatic stem cell population maintenance." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607] is_a: GO:2000036 ! regulation of stem cell population maintenance intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0035019 ! regulates (processual) somatic stem cell population maintenance relationship: RO:0002211 GO:0035019 ! regulates (processual) somatic stem cell population maintenance creation_date: 2015-09-14T08:40:19Z [Term] id: GO:1904673 name: negative regulation of somatic stem cell population maintenance namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of somatic stem cell population maintenance." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607] synonym: "down regulation of somatic stem cell population maintenance" EXACT [GOC:TermGenie] synonym: "down-regulation of somatic stem cell population maintenance" EXACT [GOC:TermGenie] synonym: "downregulation of somatic stem cell population maintenance" EXACT [GOC:TermGenie] is_a: GO:1902455 ! negative regulation of stem cell population maintenance is_a: GO:1904672 ! regulation of somatic stem cell population maintenance intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0035019 ! negatively regulates somatic stem cell population maintenance relationship: RO:0002212 GO:0035019 ! negatively regulates somatic stem cell population maintenance creation_date: 2015-09-14T08:40:25Z [Term] id: GO:1904674 name: positive regulation of somatic stem cell population maintenance namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of somatic stem cell population maintenance." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607] synonym: "up regulation of somatic stem cell population maintenance" EXACT [GOC:TermGenie] synonym: "up-regulation of somatic stem cell population maintenance" EXACT [GOC:TermGenie] synonym: "upregulation of somatic stem cell population maintenance" EXACT [GOC:TermGenie] is_a: GO:1902459 ! positive regulation of stem cell population maintenance is_a: GO:1904672 ! regulation of somatic stem cell population maintenance intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0035019 ! positively regulates somatic stem cell population maintenance relationship: RO:0002213 GO:0035019 ! positively regulates somatic stem cell population maintenance creation_date: 2015-09-14T08:40:32Z [Term] id: GO:1904675 name: regulation of somatic stem cell division namespace: biological_process def: "Any process that modulates the frequency, rate or extent of somatic stem cell division." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607] synonym: "regulation of somatic stem cell renewal" EXACT [GOC:TermGenie] is_a: GO:2000035 ! regulation of stem cell division intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048103 ! regulates (processual) somatic stem cell division relationship: RO:0002211 GO:0048103 ! regulates (processual) somatic stem cell division creation_date: 2015-09-14T08:47:22Z [Term] id: GO:1904676 name: negative regulation of somatic stem cell division namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of somatic stem cell division." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607] synonym: "down regulation of somatic stem cell division" EXACT [GOC:TermGenie] synonym: "down regulation of somatic stem cell renewal" EXACT [GOC:TermGenie] synonym: "down-regulation of somatic stem cell division" EXACT [GOC:TermGenie] synonym: "down-regulation of somatic stem cell renewal" EXACT [GOC:TermGenie] synonym: "downregulation of somatic stem cell division" EXACT [GOC:TermGenie] synonym: "downregulation of somatic stem cell renewal" EXACT [GOC:TermGenie] synonym: "negative regulation of somatic stem cell renewal" EXACT [GOC:TermGenie] is_a: GO:0051782 ! negative regulation of cell division is_a: GO:1904675 ! regulation of somatic stem cell division intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048103 ! negatively regulates somatic stem cell division relationship: RO:0002212 GO:0048103 ! negatively regulates somatic stem cell division creation_date: 2015-09-14T08:47:28Z [Term] id: GO:1904677 name: positive regulation of somatic stem cell division namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of somatic stem cell division." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607] synonym: "positive regulation of somatic stem cell renewal" EXACT [GOC:TermGenie] synonym: "up regulation of somatic stem cell division" EXACT [GOC:TermGenie] synonym: "up regulation of somatic stem cell renewal" EXACT [GOC:TermGenie] synonym: "up-regulation of somatic stem cell division" EXACT [GOC:TermGenie] synonym: "up-regulation of somatic stem cell renewal" EXACT [GOC:TermGenie] synonym: "upregulation of somatic stem cell division" EXACT [GOC:TermGenie] synonym: "upregulation of somatic stem cell renewal" EXACT [GOC:TermGenie] is_a: GO:0051781 ! positive regulation of cell division is_a: GO:1904675 ! regulation of somatic stem cell division intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0048103 ! positively regulates somatic stem cell division relationship: RO:0002213 GO:0048103 ! positively regulates somatic stem cell division creation_date: 2015-09-14T08:47:34Z [Term] id: GO:1904680 name: peptide transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of a peptide from one side of a membrane to the other." [GO_REF:0000070, GOC:TermGenie, GOC:vw] xref: Reactome:R-HSA-1500817 "Glutathione is taken up by the bacterium" is_a: GO:0042887 ! amide transmembrane transporter activity intersection_of: GO:0005215 ! transporter activity intersection_of: RO:0002342 GO:0016020 ! results in transport across membrane intersection_of: RO:0004009 CHEBI:16670 ! has primary input peptide relationship: RO:0004009 CHEBI:16670 ! has primary input peptide creation_date: 2015-09-22T18:50:41Z [Term] id: GO:1904691 name: negative regulation of type B pancreatic cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24055447] synonym: "down regulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie] synonym: "down regulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie] synonym: "down regulation of type B pancreatic cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of type B pancreatic cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of type B pancreatic cell proliferation" EXACT [GOC:TermGenie] synonym: "negative regulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie] synonym: "negative regulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0050680 ! negative regulation of epithelial cell proliferation is_a: GO:0061469 ! regulation of type B pancreatic cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0044342 ! negatively regulates type B pancreatic cell proliferation relationship: RO:0002212 GO:0044342 ! negatively regulates type B pancreatic cell proliferation creation_date: 2015-09-25T15:23:38Z [Term] id: GO:1904692 name: positive regulation of type B pancreatic cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of type B pancreatic cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24055447] synonym: "positive regulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie] synonym: "positive regulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of type B pancreatic cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of type B pancreatic cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of type B pancreatic cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0050679 ! positive regulation of epithelial cell proliferation is_a: GO:0061469 ! regulation of type B pancreatic cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0044342 ! positively regulates type B pancreatic cell proliferation relationship: RO:0002213 GO:0044342 ! positively regulates type B pancreatic cell proliferation creation_date: 2015-09-25T15:23:44Z [Term] id: GO:1904693 name: midbrain morphogenesis namespace: biological_process def: "The developmental process by which a midbrain is generated and organized." [GO_REF:0000083, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:21347250] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001891 ! results in morphogenesis of midbrain relationship: BFO:0000050 GO:0030901 ! part of midbrain development relationship: BFO:0000050 GO:0048854 ! part of brain morphogenesis relationship: RO:0002298 UBERON:0001891 ! results in morphogenesis of midbrain creation_date: 2015-09-29T09:15:28Z [Term] id: GO:1904697 name: regulation of acinar cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of acinar cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:9788538] synonym: "regulation of acinic cell proliferation" EXACT [GOC:TermGenie] synonym: "regulation of acinous cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0050678 ! regulation of epithelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1990863 ! regulates (processual) acinar cell proliferation relationship: RO:0002211 GO:1990863 ! regulates (processual) acinar cell proliferation creation_date: 2015-09-30T15:19:50Z [Term] id: GO:1904698 name: negative regulation of acinar cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of acinar cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:9788538] synonym: "down regulation of acinar cell proliferation" EXACT [GOC:TermGenie] synonym: "down regulation of acinic cell proliferation" EXACT [GOC:TermGenie] synonym: "down regulation of acinous cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of acinar cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of acinic cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of acinous cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of acinar cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of acinic cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of acinous cell proliferation" EXACT [GOC:TermGenie] synonym: "negative regulation of acinic cell proliferation" EXACT [GOC:TermGenie] synonym: "negative regulation of acinous cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0050680 ! negative regulation of epithelial cell proliferation is_a: GO:1904697 ! regulation of acinar cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1990863 ! negatively regulates acinar cell proliferation relationship: RO:0002212 GO:1990863 ! negatively regulates acinar cell proliferation creation_date: 2015-09-30T15:19:57Z [Term] id: GO:1904699 name: positive regulation of acinar cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of acinar cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:9788538] synonym: "positive regulation of acinic cell proliferation" EXACT [GOC:TermGenie] synonym: "positive regulation of acinous cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of acinar cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of acinic cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of acinous cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of acinar cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of acinic cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of acinous cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of acinar cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of acinic cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of acinous cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0050679 ! positive regulation of epithelial cell proliferation is_a: GO:1904697 ! regulation of acinar cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1990863 ! positively regulates acinar cell proliferation relationship: RO:0002213 GO:1990863 ! positively regulates acinar cell proliferation creation_date: 2015-09-30T15:20:03Z [Term] id: GO:1904705 name: regulation of vascular associated smooth muscle cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of vascular smooth muscle cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:23246467] synonym: "regulation of vascular smooth muscle cell proliferation" EXACT [] synonym: "regulation of VSMC proliferation" EXACT [GOC:TermGenie] is_a: GO:0048660 ! regulation of smooth muscle cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1990874 ! regulates (processual) vascular associated smooth muscle cell proliferation relationship: RO:0002211 GO:1990874 ! regulates (processual) vascular associated smooth muscle cell proliferation creation_date: 2015-10-01T16:05:20Z [Term] id: GO:1904706 name: negative regulation of vascular associated smooth muscle cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:23246467] synonym: "down regulation of vascular smooth muscle cell proliferation" EXACT [GOC:TermGenie] synonym: "down regulation of VSMC proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of vascular smooth muscle cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of VSMC proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of vascular smooth muscle cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of VSMC proliferation" EXACT [GOC:TermGenie] synonym: "negative regulation of vascular smooth muscle cell proliferation" EXACT [] synonym: "negative regulation of VSMC proliferation" EXACT [GOC:TermGenie] is_a: GO:0048662 ! negative regulation of smooth muscle cell proliferation is_a: GO:1904705 ! regulation of vascular associated smooth muscle cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1990874 ! negatively regulates vascular associated smooth muscle cell proliferation relationship: RO:0002212 GO:1990874 ! negatively regulates vascular associated smooth muscle cell proliferation creation_date: 2015-10-01T16:05:26Z [Term] id: GO:1904707 name: positive regulation of vascular associated smooth muscle cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:23246467] synonym: "positive regulation of vascular smooth muscle cell proliferation" EXACT [] synonym: "positive regulation of VSMC proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of vascular smooth muscle cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of VSMC proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of vascular smooth muscle cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of VSMC proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of vascular smooth muscle cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of VSMC proliferation" EXACT [GOC:TermGenie] is_a: GO:0048661 ! positive regulation of smooth muscle cell proliferation is_a: GO:1904705 ! regulation of vascular associated smooth muscle cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1990874 ! positively regulates vascular associated smooth muscle cell proliferation relationship: RO:0002213 GO:1990874 ! positively regulates vascular associated smooth muscle cell proliferation creation_date: 2015-10-01T16:05:32Z [Term] id: GO:1904738 name: vascular associated smooth muscle cell migration namespace: biological_process def: "The orderly movement of a vascular associated smooth muscle cell from one site to another." [GO_REF:0000091, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:20693317] synonym: "vascular smooth muscle cell migration" EXACT [] is_a: GO:0014909 ! smooth muscle cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000359 ! results in movement of vascular associated smooth muscle cell relationship: RO:0002565 CL:0000359 ! results in movement of vascular associated smooth muscle cell creation_date: 2015-10-15T09:56:00Z [Term] id: GO:1904746 name: negative regulation of apoptotic process involved in development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in development." [GO_REF:0000058, GOC:TermGenie, PMID:22801495] synonym: "down regulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic process involved in development" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "down regulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "down regulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic process involved in development" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "down-regulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "down-regulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic process involved in development" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "downregulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "downregulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "negative regulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "negative regulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "negative regulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "negative regulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "negative regulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "negative regulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "negative regulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "negative regulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] is_a: GO:0043066 ! negative regulation of apoptotic process is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:1904748 ! regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1902742 ! negatively regulates apoptotic process involved in development relationship: RO:0002212 GO:1902742 ! negatively regulates apoptotic process involved in development creation_date: 2015-10-19T14:12:27Z [Term] id: GO:1904747 name: positive regulation of apoptotic process involved in development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in development." [GO_REF:0000058, GOC:TermGenie, PMID:22801495] synonym: "positive regulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "positive regulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "positive regulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "positive regulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "positive regulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "positive regulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "positive regulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "positive regulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic process involved in development" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "up regulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "up regulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic process involved in development" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "up-regulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "up-regulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic process involved in development" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "upregulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "upregulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] is_a: GO:0043065 ! positive regulation of apoptotic process is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:1904748 ! regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1902742 ! positively regulates apoptotic process involved in development relationship: RO:0002213 GO:1902742 ! positively regulates apoptotic process involved in development creation_date: 2015-10-19T14:12:34Z [Term] id: GO:1904748 name: regulation of apoptotic process involved in development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of apoptotic process involved in development." [GO_REF:0000058, GOC:TermGenie, PMID:22801495] synonym: "regulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "regulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "regulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "regulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "regulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "regulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "regulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "regulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] is_a: GO:0042981 ! regulation of apoptotic process is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1902742 ! regulates (processual) apoptotic process involved in development relationship: RO:0002211 GO:1902742 ! regulates (processual) apoptotic process involved in development creation_date: 2015-10-19T15:02:28Z [Term] id: GO:1904749 name: regulation of protein localization to nucleolus namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein localization to nucleolus." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:24415760] synonym: "regulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] synonym: "regulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] synonym: "regulation of protein localization in nucleolus" EXACT [GOC:TermGenie] is_a: GO:1900180 ! regulation of protein localization to nucleus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1902570 ! regulates (processual) protein localization to nucleolus relationship: RO:0002211 GO:1902570 ! regulates (processual) protein localization to nucleolus creation_date: 2015-10-19T15:16:17Z [Term] id: GO:1904750 name: negative regulation of protein localization to nucleolus namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleolus." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:24415760] synonym: "down regulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] synonym: "down regulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization in nucleolus" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization to nucleolus" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization in nucleolus" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to nucleolus" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization in nucleolus" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to nucleolus" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localization in nucleolus" EXACT [GOC:TermGenie] is_a: GO:1900181 ! negative regulation of protein localization to nucleus is_a: GO:1904749 ! regulation of protein localization to nucleolus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1902570 ! negatively regulates protein localization to nucleolus relationship: RO:0002212 GO:1902570 ! negatively regulates protein localization to nucleolus creation_date: 2015-10-19T15:16:24Z [Term] id: GO:1904751 name: positive regulation of protein localization to nucleolus namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein localization to nucleolus." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:24415760] synonym: "positive regulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localization in nucleolus" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization in nucleolus" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization to nucleolus" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization in nucleolus" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to nucleolus" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization in nucleolus" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to nucleolus" EXACT [GOC:TermGenie] is_a: GO:1900182 ! positive regulation of protein localization to nucleus is_a: GO:1904749 ! regulation of protein localization to nucleolus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1902570 ! positively regulates protein localization to nucleolus relationship: RO:0002213 GO:1902570 ! positively regulates protein localization to nucleolus creation_date: 2015-10-19T15:16:30Z [Term] id: GO:1904752 name: regulation of vascular associated smooth muscle cell migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell migration." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:20693317] synonym: "regulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] is_a: GO:0014910 ! regulation of smooth muscle cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1904738 ! regulates (processual) vascular associated smooth muscle cell migration relationship: RO:0002211 GO:1904738 ! regulates (processual) vascular associated smooth muscle cell migration creation_date: 2015-10-19T15:49:52Z [Term] id: GO:1904753 name: negative regulation of vascular associated smooth muscle cell migration namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell migration." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:20693317] synonym: "down regulation of vascular associated smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "down regulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "down-regulation of vascular associated smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "down-regulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "downregulation of vascular associated smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "downregulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "negative regulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] is_a: GO:0014912 ! negative regulation of smooth muscle cell migration is_a: GO:1904752 ! regulation of vascular associated smooth muscle cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1904738 ! negatively regulates vascular associated smooth muscle cell migration relationship: RO:0002212 GO:1904738 ! negatively regulates vascular associated smooth muscle cell migration creation_date: 2015-10-19T15:49:58Z [Term] id: GO:1904754 name: positive regulation of vascular associated smooth muscle cell migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell migration." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:20693317] synonym: "positive regulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "up regulation of vascular associated smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "up regulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "up-regulation of vascular associated smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "up-regulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "upregulation of vascular associated smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "upregulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] is_a: GO:0014911 ! positive regulation of smooth muscle cell migration is_a: GO:1904752 ! regulation of vascular associated smooth muscle cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1904738 ! positively regulates vascular associated smooth muscle cell migration relationship: RO:0002213 GO:1904738 ! positively regulates vascular associated smooth muscle cell migration creation_date: 2015-10-19T15:50:05Z [Term] id: GO:1904770 name: intramembranous bone morphogenesis namespace: biological_process def: "The developmental process by which an intramembranous bone is generated and organized." [GO_REF:0000083, GOC:TermGenie, PMID:26399686] is_a: GO:0060349 ! bone morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002514 ! results in morphogenesis of intramembranous bone relationship: RO:0002298 UBERON:0002514 ! results in morphogenesis of intramembranous bone creation_date: 2015-10-28T11:46:04Z [Term] id: GO:1904776 name: regulation of protein localization to cell cortex namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein localization to cell cortex." [GO_REF:0000058, GOC:TermGenie, PMID:17115027] synonym: "regulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] is_a: GO:1904375 ! regulation of protein localization to cell periphery intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0072697 ! regulates (processual) protein localization to cell cortex relationship: RO:0002211 GO:0072697 ! regulates (processual) protein localization to cell cortex creation_date: 2015-10-29T16:55:01Z [Term] id: GO:1904777 name: negative regulation of protein localization to cell cortex namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell cortex." [GO_REF:0000058, GOC:TermGenie, PMID:17115027] synonym: "down regulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization to cell cortex" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to cell cortex" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to cell cortex" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] is_a: GO:1904376 ! negative regulation of protein localization to cell periphery is_a: GO:1904776 ! regulation of protein localization to cell cortex intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0072697 ! negatively regulates protein localization to cell cortex relationship: RO:0002212 GO:0072697 ! negatively regulates protein localization to cell cortex creation_date: 2015-10-29T16:55:08Z [Term] id: GO:1904778 name: positive regulation of protein localization to cell cortex namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein localization to cell cortex." [GO_REF:0000058, GOC:TermGenie, PMID:17115027] synonym: "positive regulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization to cell cortex" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to cell cortex" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to cell cortex" EXACT [GOC:TermGenie] is_a: GO:1904377 ! positive regulation of protein localization to cell periphery is_a: GO:1904776 ! regulation of protein localization to cell cortex intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0072697 ! positively regulates protein localization to cell cortex relationship: RO:0002213 GO:0072697 ! positively regulates protein localization to cell cortex creation_date: 2015-10-29T16:55:15Z [Term] id: GO:1904817 name: serous membrane development namespace: biological_process def: "The process whose specific outcome is the progression of a serous membrane over time, from its formation to the mature structure." [GO_REF:0000094, GOC:dph, GOC:TermGenie, PMID:15840053] synonym: "tunica serosa development" EXACT [GOC:TermGenie] synonym: "wall of serous sac development" EXACT [GOC:TermGenie] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000042 ! results in development of serous membrane relationship: RO:0002296 UBERON:0000042 ! results in development of serous membrane creation_date: 2015-11-17T19:00:01Z [Term] id: GO:1904818 name: visceral peritoneum development namespace: biological_process def: "The process whose specific outcome is the progression of a visceral peritoneum over time, from its formation to the mature structure." [GO_REF:0000094, GOC:dph, GOC:TermGenie, PMID:15840053] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001178 ! results in development of visceral peritoneum relationship: BFO:0000050 GO:1904820 ! part of peritoneum development relationship: RO:0002296 UBERON:0001178 ! results in development of visceral peritoneum creation_date: 2015-11-17T19:00:17Z [Term] id: GO:1904819 name: parietal peritoneum development namespace: biological_process def: "The process whose specific outcome is the progression of a parietal peritoneum over time, from its formation to the mature structure." [GO_REF:0000094, GOC:dph, GOC:TermGenie, PMID:15840053] synonym: "peritoneal cavity lining development" EXACT [GOC:TermGenie] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001366 ! results in development of parietal peritoneum relationship: BFO:0000050 GO:1904820 ! part of peritoneum development relationship: RO:0002296 UBERON:0001366 ! results in development of parietal peritoneum creation_date: 2015-11-17T19:00:24Z [Term] id: GO:1904820 name: peritoneum development namespace: biological_process def: "The process whose specific outcome is the progression of a peritoneum over time, from its formation to the mature structure." [GO_REF:0000094, GOC:dph, GOC:TermGenie, PMID:15840053] is_a: GO:1904817 ! serous membrane development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002358 ! results in development of peritoneum relationship: RO:0002296 UBERON:0002358 ! results in development of peritoneum creation_date: 2015-11-18T17:23:51Z [Term] id: GO:1904829 name: regulation of aortic smooth muscle cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of aortic smooth muscle cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22034194] is_a: GO:1905063 ! regulation of vascular associated smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0035887 ! regulates (processual) aortic smooth muscle cell differentiation relationship: RO:0002211 GO:0035887 ! regulates (processual) aortic smooth muscle cell differentiation creation_date: 2015-11-24T10:20:40Z [Term] id: GO:1904830 name: negative regulation of aortic smooth muscle cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of aortic smooth muscle cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22034194] synonym: "down regulation of aortic smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of aortic smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of aortic smooth muscle cell differentiation" EXACT [GOC:TermGenie] is_a: GO:1904829 ! regulation of aortic smooth muscle cell differentiation is_a: GO:1905064 ! negative regulation of vascular associated smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0035887 ! negatively regulates aortic smooth muscle cell differentiation relationship: RO:0002212 GO:0035887 ! negatively regulates aortic smooth muscle cell differentiation creation_date: 2015-11-24T10:20:47Z [Term] id: GO:1904831 name: positive regulation of aortic smooth muscle cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of aortic smooth muscle cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22034194] synonym: "up regulation of aortic smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of aortic smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of aortic smooth muscle cell differentiation" EXACT [GOC:TermGenie] is_a: GO:1904829 ! regulation of aortic smooth muscle cell differentiation is_a: GO:1905065 ! positive regulation of vascular associated smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0035887 ! positively regulates aortic smooth muscle cell differentiation relationship: RO:0002213 GO:0035887 ! positively regulates aortic smooth muscle cell differentiation creation_date: 2015-11-24T10:20:54Z [Term] id: GO:1904888 name: cranial skeletal system development namespace: biological_process def: "The process whose specific outcome is the progression of a cranial skeletal system over time, from its formation to the mature structure. The cranial skeletal system is the skeletal subdivision of the head, and includes the skull (cranium plus mandible), pharyngeal and/or hyoid apparatus." [GO_REF:0000094, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:11262227] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0010323 ! results in development of cranial skeletal system relationship: RO:0002296 UBERON:0010323 ! results in development of cranial skeletal system creation_date: 2016-01-07T13:45:06Z [Term] id: GO:1904933 name: regulation of cell proliferation in midbrain namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell proliferation in midbrain." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:18953410, PMID:24431302] synonym: "regulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] is_a: GO:2000177 ! regulation of neural precursor cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0033278 ! regulates (processual) cell proliferation in midbrain relationship: RO:0002211 GO:0033278 ! regulates (processual) cell proliferation in midbrain creation_date: 2016-02-01T13:16:11Z [Term] id: GO:1904934 name: negative regulation of cell proliferation in midbrain namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in midbrain." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:18953410, PMID:24431302] synonym: "down regulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] synonym: "down regulation of cell proliferation in midbrain" EXACT [GOC:TermGenie] synonym: "down-regulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] synonym: "down-regulation of cell proliferation in midbrain" EXACT [GOC:TermGenie] synonym: "downregulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] synonym: "downregulation of cell proliferation in midbrain" EXACT [GOC:TermGenie] synonym: "negative regulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] is_a: GO:1904933 ! regulation of cell proliferation in midbrain is_a: GO:2000178 ! negative regulation of neural precursor cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0033278 ! negatively regulates cell proliferation in midbrain relationship: RO:0002212 GO:0033278 ! negatively regulates cell proliferation in midbrain creation_date: 2016-02-01T13:16:19Z [Term] id: GO:1904935 name: positive regulation of cell proliferation in midbrain namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell proliferation in midbrain." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24431302] synonym: "positive regulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] synonym: "up regulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] synonym: "up regulation of cell proliferation in midbrain" EXACT [GOC:TermGenie] synonym: "up-regulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] synonym: "up-regulation of cell proliferation in midbrain" EXACT [GOC:TermGenie] synonym: "upregulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] synonym: "upregulation of cell proliferation in midbrain" EXACT [GOC:TermGenie] is_a: GO:1904933 ! regulation of cell proliferation in midbrain is_a: GO:2000179 ! positive regulation of neural precursor cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0033278 ! positively regulates cell proliferation in midbrain relationship: RO:0002213 GO:0033278 ! positively regulates cell proliferation in midbrain creation_date: 2016-02-01T13:16:27Z [Term] id: GO:1904936 name: interneuron migration namespace: biological_process def: "The orderly movement of an interneuron from one site to another." [GO_REF:0000091, GOC:ah, GOC:TermGenie, PMID:18622031] synonym: "inter neuron migration" EXACT [GOC:ah] synonym: "inter-neuron migration" EXACT [GOC:ah] is_a: GO:0001764 ! neuron migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000099 ! results in movement of interneuron relationship: RO:0002565 CL:0000099 ! results in movement of interneuron creation_date: 2016-02-01T14:04:32Z [Term] id: GO:1904937 name: sensory neuron migration namespace: biological_process def: "The orderly movement of a sensory neuron from one site to another." [GO_REF:0000091, GOC:ah, GOC:TermGenie, PMID:18622031] is_a: GO:0001764 ! neuron migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000101 ! results in movement of sensory neuron relationship: RO:0002565 CL:0000101 ! results in movement of sensory neuron creation_date: 2016-02-01T14:15:50Z [Term] id: GO:1904942 name: regulation of cardiac ventricle formation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac ventricle formation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23575307] is_a: GO:1901210 ! regulation of cardiac chamber formation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003211 ! regulates (processual) cardiac ventricle formation relationship: RO:0002211 GO:0003211 ! regulates (processual) cardiac ventricle formation creation_date: 2016-02-02T16:37:16Z [Term] id: GO:1904943 name: negative regulation of cardiac ventricle formation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle formation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23575307] synonym: "down regulation of cardiac ventricle formation" EXACT [GOC:TermGenie] synonym: "down-regulation of cardiac ventricle formation" EXACT [GOC:TermGenie] synonym: "downregulation of cardiac ventricle formation" EXACT [GOC:TermGenie] is_a: GO:1901211 ! negative regulation of cardiac chamber formation is_a: GO:1904413 ! negative regulation of cardiac ventricle development is_a: GO:1904942 ! regulation of cardiac ventricle formation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0003211 ! negatively regulates cardiac ventricle formation relationship: RO:0002212 GO:0003211 ! negatively regulates cardiac ventricle formation creation_date: 2016-02-02T16:37:24Z [Term] id: GO:1904944 name: positive regulation of cardiac ventricle formation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cardiac ventricle formation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23575307] synonym: "up regulation of cardiac ventricle formation" EXACT [GOC:TermGenie] synonym: "up-regulation of cardiac ventricle formation" EXACT [GOC:TermGenie] synonym: "upregulation of cardiac ventricle formation" EXACT [GOC:TermGenie] is_a: GO:1901212 ! positive regulation of cardiac chamber formation is_a: GO:1904942 ! regulation of cardiac ventricle formation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0003211 ! positively regulates cardiac ventricle formation relationship: RO:0002213 GO:0003211 ! positively regulates cardiac ventricle formation creation_date: 2016-02-02T16:37:31Z [Term] id: GO:1904950 name: negative regulation of establishment of protein localization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization." [GO_REF:0000058, GOC:TermGenie, PMID:22761445] synonym: "down regulation of establishment of protein localisation" EXACT [GOC:TermGenie] synonym: "down regulation of establishment of protein localization" EXACT [GOC:TermGenie] synonym: "down regulation of protein positioning" EXACT [GOC:TermGenie] synonym: "down regulation of protein recruitment" EXACT [GOC:TermGenie] synonym: "down-regulation of establishment of protein localisation" EXACT [GOC:TermGenie] synonym: "down-regulation of establishment of protein localization" EXACT [GOC:TermGenie] synonym: "down-regulation of protein positioning" EXACT [GOC:TermGenie] synonym: "down-regulation of protein recruitment" EXACT [GOC:TermGenie] synonym: "downregulation of establishment of protein localisation" EXACT [GOC:TermGenie] synonym: "downregulation of establishment of protein localization" EXACT [GOC:TermGenie] synonym: "downregulation of protein positioning" EXACT [GOC:TermGenie] synonym: "downregulation of protein recruitment" EXACT [GOC:TermGenie] synonym: "negative regulation of establishment of protein localisation" EXACT [GOC:TermGenie] synonym: "negative regulation of protein positioning" EXACT [GOC:TermGenie] synonym: "negative regulation of protein recruitment" EXACT [GOC:TermGenie] is_a: GO:0048519 ! negative regulation of biological process is_a: GO:0070201 ! regulation of establishment of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0045184 ! negatively regulates establishment of protein localization relationship: RO:0002212 GO:0045184 ! negatively regulates establishment of protein localization creation_date: 2016-02-05T09:59:24Z [Term] id: GO:1904951 name: positive regulation of establishment of protein localization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of establishment of protein localization." [GO_REF:0000058, GOC:TermGenie, PMID:22761445] synonym: "positive regulation of establishment of protein localisation" EXACT [GOC:TermGenie] synonym: "positive regulation of protein positioning" EXACT [GOC:TermGenie] synonym: "positive regulation of protein recruitment" EXACT [GOC:TermGenie] synonym: "up regulation of establishment of protein localisation" EXACT [GOC:TermGenie] synonym: "up regulation of establishment of protein localization" EXACT [GOC:TermGenie] synonym: "up regulation of protein positioning" EXACT [GOC:TermGenie] synonym: "up regulation of protein recruitment" EXACT [GOC:TermGenie] synonym: "up-regulation of establishment of protein localisation" EXACT [GOC:TermGenie] synonym: "up-regulation of establishment of protein localization" EXACT [GOC:TermGenie] synonym: "up-regulation of protein positioning" EXACT [GOC:TermGenie] synonym: "up-regulation of protein recruitment" EXACT [GOC:TermGenie] synonym: "upregulation of establishment of protein localisation" EXACT [GOC:TermGenie] synonym: "upregulation of establishment of protein localization" EXACT [GOC:TermGenie] synonym: "upregulation of protein positioning" EXACT [GOC:TermGenie] synonym: "upregulation of protein recruitment" EXACT [GOC:TermGenie] is_a: GO:0048518 ! positive regulation of biological process is_a: GO:0070201 ! regulation of establishment of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0045184 ! positively regulates establishment of protein localization relationship: RO:0002213 GO:0045184 ! positively regulates establishment of protein localization creation_date: 2016-02-05T09:59:32Z [Term] id: GO:1904987 name: regulation of endothelial cell activation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of endothelial cell activation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:24255059] is_a: GO:0050865 ! regulation of cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0042118 ! regulates (processual) endothelial cell activation relationship: RO:0002211 GO:0042118 ! regulates (processual) endothelial cell activation creation_date: 2016-02-29T16:16:09Z [Term] id: GO:1904988 name: negative regulation of endothelial cell activation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell activation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:24255059] synonym: "down regulation of endothelial cell activation" EXACT [GOC:TermGenie] synonym: "down-regulation of endothelial cell activation" EXACT [GOC:TermGenie] synonym: "downregulation of endothelial cell activation" EXACT [GOC:TermGenie] is_a: GO:0050866 ! negative regulation of cell activation is_a: GO:1904987 ! regulation of endothelial cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0042118 ! negatively regulates endothelial cell activation relationship: RO:0002212 GO:0042118 ! negatively regulates endothelial cell activation creation_date: 2016-02-29T16:16:18Z [Term] id: GO:1904989 name: positive regulation of endothelial cell activation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of endothelial cell activation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:24255059] synonym: "up regulation of endothelial cell activation" EXACT [GOC:TermGenie] synonym: "up-regulation of endothelial cell activation" EXACT [GOC:TermGenie] synonym: "upregulation of endothelial cell activation" EXACT [GOC:TermGenie] is_a: GO:0050867 ! positive regulation of cell activation is_a: GO:1904987 ! regulation of endothelial cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0042118 ! positively regulates endothelial cell activation relationship: RO:0002213 GO:0042118 ! positively regulates endothelial cell activation creation_date: 2016-02-29T16:16:25Z [Term] id: GO:1905039 name: carboxylic acid transmembrane transport namespace: biological_process def: "The process in which carboxylic acid is transported across a membrane." [GO_REF:0000069, GOC:TermGenie, PMID:10869563] is_a: GO:0046942 ! carboxylic acid transport is_a: GO:0055085 ! transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002342 GO:0016020 ! results in transport across membrane intersection_of: RO:0004009 CHEBI:29067 ! has primary input carboxylic acid anion creation_date: 2016-03-09T15:33:53Z [Term] id: GO:1905063 name: regulation of vascular associated smooth muscle cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of vascular smooth muscle cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19088079] synonym: "regulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "regulation of VSMC differentiation" EXACT [GOC:TermGenie] is_a: GO:0051150 ! regulation of smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0035886 ! regulates (processual) vascular associated smooth muscle cell differentiation relationship: RO:0002211 GO:0035886 ! regulates (processual) vascular associated smooth muscle cell differentiation creation_date: 2016-03-21T11:14:53Z [Term] id: GO:1905064 name: negative regulation of vascular associated smooth muscle cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19088079] synonym: "down regulation of vascular associated smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of VSMC differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of vascular associated smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of VSMC differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of vascular associated smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of VSMC differentiation" EXACT [GOC:TermGenie] synonym: "negative regulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "negative regulation of VSMC differentiation" EXACT [GOC:TermGenie] is_a: GO:0051151 ! negative regulation of smooth muscle cell differentiation is_a: GO:1905063 ! regulation of vascular associated smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0035886 ! negatively regulates vascular associated smooth muscle cell differentiation relationship: RO:0002212 GO:0035886 ! negatively regulates vascular associated smooth muscle cell differentiation creation_date: 2016-03-21T11:15:03Z [Term] id: GO:1905065 name: positive regulation of vascular associated smooth muscle cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19088079] synonym: "positive regulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "positive regulation of VSMC differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of vascular associated smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of VSMC differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of vascular associated smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of VSMC differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of vascular associated smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of VSMC differentiation" EXACT [GOC:TermGenie] is_a: GO:0051152 ! positive regulation of smooth muscle cell differentiation is_a: GO:1905063 ! regulation of vascular associated smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0035886 ! positively regulates vascular associated smooth muscle cell differentiation relationship: RO:0002213 GO:0035886 ! positively regulates vascular associated smooth muscle cell differentiation creation_date: 2016-03-21T11:15:13Z [Term] id: GO:1905069 name: allantois development namespace: biological_process def: "The process whose specific outcome is the progression of an allantois over time, from its formation to the mature structure." [GO_REF:0000094, GOC:TermGenie, PMID:17440924, PMID:21470579] is_a: GO:1903867 ! extraembryonic membrane development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004340 ! results in development of allantois relationship: RO:0002296 UBERON:0004340 ! results in development of allantois creation_date: 2016-03-21T15:18:21Z [Term] id: GO:1905126 name: regulation of axo-dendritic protein transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of axo-dendritic protein transport." [GO_REF:0000058, GOC:TermGenie, PMID:20694152] is_a: GO:0033157 ! regulation of intracellular protein transport is_a: GO:0060632 ! regulation of microtubule-based movement intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0099640 ! regulates (processual) axo-dendritic protein transport relationship: RO:0002211 GO:0099640 ! regulates (processual) axo-dendritic protein transport creation_date: 2016-04-11T20:38:31Z [Term] id: GO:1905127 name: negative regulation of axo-dendritic protein transport namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of axo-dendritic protein transport." [GO_REF:0000058, GOC:TermGenie, PMID:20694152] synonym: "down regulation of axo-dendritic protein transport" EXACT [GOC:TermGenie] synonym: "down-regulation of axo-dendritic protein transport" EXACT [GOC:TermGenie] synonym: "downregulation of axo-dendritic protein transport" EXACT [GOC:TermGenie] is_a: GO:0090317 ! negative regulation of intracellular protein transport is_a: GO:1905126 ! regulation of axo-dendritic protein transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0099640 ! negatively regulates axo-dendritic protein transport relationship: RO:0002212 GO:0099640 ! negatively regulates axo-dendritic protein transport creation_date: 2016-04-11T20:38:40Z [Term] id: GO:1905128 name: positive regulation of axo-dendritic protein transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of axo-dendritic protein transport." [GO_REF:0000058, GOC:TermGenie, PMID:20694152] synonym: "up regulation of axo-dendritic protein transport" EXACT [GOC:TermGenie] synonym: "up-regulation of axo-dendritic protein transport" EXACT [GOC:TermGenie] synonym: "upregulation of axo-dendritic protein transport" EXACT [GOC:TermGenie] is_a: GO:0090316 ! positive regulation of intracellular protein transport is_a: GO:1905126 ! regulation of axo-dendritic protein transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0099640 ! positively regulates axo-dendritic protein transport relationship: RO:0002213 GO:0099640 ! positively regulates axo-dendritic protein transport creation_date: 2016-04-11T20:38:48Z [Term] id: GO:1905139 name: apical ectodermal ridge formation namespace: biological_process def: "The process that gives rise to the apical ectodermal ridge. This process pertains to the initial formation of a structure from unspecified parts." [GO_REF:0000081, GOC:TermGenie, PMID:18359901, PMID:9323126, PMID:9596583] synonym: "apical epidermal ridge formation" EXACT [GOC:TermGenie] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0004356 ! results in formation of anatomical entity apical ectodermal ridge relationship: BFO:0000050 GO:0035107 ! part of appendage morphogenesis relationship: RO:0002297 UBERON:0004356 ! results in formation of anatomical entity apical ectodermal ridge creation_date: 2016-04-13T11:46:40Z [Term] id: GO:1905140 name: regulation of apical ectodermal ridge formation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of apical ectodermal ridge formation." [GO_REF:0000058, GOC:TermGenie, PMID:18359901] synonym: "regulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1905139 ! regulates (processual) apical ectodermal ridge formation relationship: RO:0002211 GO:1905139 ! regulates (processual) apical ectodermal ridge formation creation_date: 2016-04-13T12:16:40Z [Term] id: GO:1905141 name: negative regulation of apical ectodermal ridge formation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of apical ectodermal ridge formation." [GO_REF:0000058, GOC:TermGenie, PMID:18359901] synonym: "down regulation of apical ectodermal ridge formation" EXACT [GOC:TermGenie] synonym: "down regulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] synonym: "down-regulation of apical ectodermal ridge formation" EXACT [GOC:TermGenie] synonym: "down-regulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] synonym: "downregulation of apical ectodermal ridge formation" EXACT [GOC:TermGenie] synonym: "downregulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] synonym: "negative regulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1905140 ! regulation of apical ectodermal ridge formation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1905139 ! negatively regulates apical ectodermal ridge formation relationship: RO:0002212 GO:1905139 ! negatively regulates apical ectodermal ridge formation creation_date: 2016-04-13T12:16:48Z [Term] id: GO:1905142 name: positive regulation of apical ectodermal ridge formation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of apical ectodermal ridge formation." [GO_REF:0000058, GOC:TermGenie, PMID:18359901] synonym: "positive regulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] synonym: "up regulation of apical ectodermal ridge formation" EXACT [GOC:TermGenie] synonym: "up regulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] synonym: "up-regulation of apical ectodermal ridge formation" EXACT [GOC:TermGenie] synonym: "up-regulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] synonym: "upregulation of apical ectodermal ridge formation" EXACT [GOC:TermGenie] synonym: "upregulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1905140 ! regulation of apical ectodermal ridge formation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1905139 ! positively regulates apical ectodermal ridge formation relationship: RO:0002213 GO:1905139 ! positively regulates apical ectodermal ridge formation creation_date: 2016-04-13T12:16:57Z [Term] id: GO:1905144 name: response to acetylcholine namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:21238497] is_a: GO:0010033 ! response to organic substance is_a: GO:1901698 ! response to nitrogen compound is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:15355 ! has primary input acetylcholine relationship: RO:0004009 CHEBI:15355 ! has primary input acetylcholine creation_date: 2016-04-14T08:54:49Z [Term] id: GO:1905147 name: regulation of smooth muscle hypertrophy namespace: biological_process def: "Any process that modulates the frequency, rate or extent of smooth muscle hypertrophy." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:22161164] is_a: GO:0014743 ! regulation of muscle hypertrophy is_a: GO:0043502 ! regulation of muscle adaptation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0014895 ! regulates (processual) smooth muscle hypertrophy relationship: RO:0002211 GO:0014895 ! regulates (processual) smooth muscle hypertrophy creation_date: 2016-04-15T12:47:07Z [Term] id: GO:1905148 name: negative regulation of smooth muscle hypertrophy namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle hypertrophy." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:22161164] synonym: "down regulation of smooth muscle hypertrophy" EXACT [GOC:TermGenie] synonym: "down-regulation of smooth muscle hypertrophy" EXACT [GOC:TermGenie] synonym: "downregulation of smooth muscle hypertrophy" EXACT [GOC:TermGenie] is_a: GO:0014741 ! negative regulation of muscle hypertrophy is_a: GO:0014745 ! negative regulation of muscle adaptation is_a: GO:1905147 ! regulation of smooth muscle hypertrophy intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0014895 ! negatively regulates smooth muscle hypertrophy relationship: RO:0002212 GO:0014895 ! negatively regulates smooth muscle hypertrophy creation_date: 2016-04-15T12:47:16Z [Term] id: GO:1905149 name: positive regulation of smooth muscle hypertrophy namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of smooth muscle hypertrophy." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:22161164] synonym: "up regulation of smooth muscle hypertrophy" EXACT [GOC:TermGenie] synonym: "up-regulation of smooth muscle hypertrophy" EXACT [GOC:TermGenie] synonym: "upregulation of smooth muscle hypertrophy" EXACT [GOC:TermGenie] is_a: GO:0014742 ! positive regulation of muscle hypertrophy is_a: GO:0014744 ! positive regulation of muscle adaptation is_a: GO:1905147 ! regulation of smooth muscle hypertrophy intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0014895 ! positively regulates smooth muscle hypertrophy relationship: RO:0002213 GO:0014895 ! positively regulates smooth muscle hypertrophy creation_date: 2016-04-15T12:47:24Z [Term] id: GO:1905153 name: regulation of membrane invagination namespace: biological_process def: "Any process that modulates the frequency, rate or extent of membrane invagination." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:26589353] is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0010324 ! regulates (processual) membrane invagination relationship: RO:0002211 GO:0010324 ! regulates (processual) membrane invagination creation_date: 2016-04-18T15:43:54Z [Term] id: GO:1905154 name: negative regulation of membrane invagination namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of membrane invagination." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:26589353] synonym: "down regulation of membrane invagination" EXACT [GOC:TermGenie] synonym: "down-regulation of membrane invagination" EXACT [GOC:TermGenie] synonym: "downregulation of membrane invagination" EXACT [GOC:TermGenie] is_a: GO:0051129 ! negative regulation of cellular component organization is_a: GO:1905153 ! regulation of membrane invagination intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0010324 ! negatively regulates membrane invagination relationship: RO:0002212 GO:0010324 ! negatively regulates membrane invagination creation_date: 2016-04-18T15:44:04Z [Term] id: GO:1905155 name: positive regulation of membrane invagination namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of membrane invagination." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] synonym: "up regulation of membrane invagination" EXACT [GOC:TermGenie] synonym: "up-regulation of membrane invagination" EXACT [GOC:TermGenie] synonym: "upregulation of membrane invagination" EXACT [GOC:TermGenie] is_a: GO:0051130 ! positive regulation of cellular component organization is_a: GO:1905153 ! regulation of membrane invagination intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0010324 ! positively regulates membrane invagination relationship: RO:0002213 GO:0010324 ! positively regulates membrane invagination creation_date: 2016-04-18T15:44:12Z [Term] id: GO:1905207 name: regulation of cardiocyte differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiocyte differentiation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23069713] synonym: "regulation of cardiac cell differentiation" EXACT [GOC:TermGenie] synonym: "regulation of heart cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0035051 ! regulates (processual) cardiocyte differentiation relationship: RO:0002211 GO:0035051 ! regulates (processual) cardiocyte differentiation creation_date: 2016-06-02T07:20:01Z [Term] id: GO:1905208 name: negative regulation of cardiocyte differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiocyte differentiation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23069713] synonym: "down regulation of cardiac cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of cardiocyte differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of heart cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of cardiac cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of cardiocyte differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of heart cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of cardiac cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of cardiocyte differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of heart cell differentiation" EXACT [GOC:TermGenie] synonym: "negative regulation of cardiac cell differentiation" EXACT [GOC:TermGenie] synonym: "negative regulation of heart cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1905207 ! regulation of cardiocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0035051 ! negatively regulates cardiocyte differentiation relationship: RO:0002212 GO:0035051 ! negatively regulates cardiocyte differentiation creation_date: 2016-06-02T07:20:09Z [Term] id: GO:1905209 name: positive regulation of cardiocyte differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cardiocyte differentiation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23069713] synonym: "positive regulation of cardiac cell differentiation" EXACT [GOC:TermGenie] synonym: "positive regulation of heart cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of cardiac cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of cardiocyte differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of heart cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of cardiac cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of cardiocyte differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of heart cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of cardiac cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of cardiocyte differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of heart cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1905207 ! regulation of cardiocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0035051 ! positively regulates cardiocyte differentiation relationship: RO:0002213 GO:0035051 ! positively regulates cardiocyte differentiation creation_date: 2016-06-02T07:20:16Z [Term] id: GO:1905213 name: negative regulation of mitotic chromosome condensation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic chromosome condensation." [GO_REF:0000058, GOC:TermGenie, PMID:23219725] is_a: GO:0010948 ! negative regulation of cell cycle process is_a: GO:1902340 ! negative regulation of chromosome condensation is_a: GO:1903379 ! regulation of mitotic chromosome condensation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007076 ! negatively regulates mitotic chromosome condensation relationship: RO:0002212 GO:0007076 ! negatively regulates mitotic chromosome condensation creation_date: 2016-06-03T08:41:08Z [Term] id: GO:1905223 name: epicardium morphogenesis namespace: biological_process def: "The developmental process by which an epicardium is generated and organized." [GO_REF:0000083, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:18718461] synonym: "heart epicardium morphogenesis" EXACT [GOC:TermGenie] synonym: "visceral serous pericardium of heart morphogenesis" EXACT [GOC:TermGenie] synonym: "visceral serous pericardium proper morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002348 ! results in morphogenesis of epicardium relationship: RO:0002298 UBERON:0002348 ! results in morphogenesis of epicardium creation_date: 2016-06-07T10:02:32Z [Term] id: GO:1905268 name: negative regulation of chromatin organization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of chromatin organization." [GO_REF:0000058, GOC:pr, GOC:TermGenie, GOC:vw, PMID:654321] synonym: "down regulation of chromatin organisation" EXACT [GOC:TermGenie] synonym: "down regulation of chromatin organization" EXACT [GOC:TermGenie] synonym: "down regulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] synonym: "down-regulation of chromatin organisation" EXACT [GOC:TermGenie] synonym: "down-regulation of chromatin organization" EXACT [GOC:TermGenie] synonym: "down-regulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] synonym: "downregulation of chromatin organisation" EXACT [GOC:TermGenie] synonym: "downregulation of chromatin organization" EXACT [GOC:TermGenie] synonym: "downregulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] synonym: "negative regulation of chromatin assembly/disassembly" EXACT [] synonym: "negative regulation of chromatin organisation" EXACT [GOC:TermGenie] synonym: "negative regulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] is_a: GO:0051129 ! negative regulation of cellular component organization is_a: GO:1902275 ! regulation of chromatin organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006325 ! negatively regulates chromatin organization relationship: RO:0002212 GO:0006325 ! negatively regulates chromatin organization creation_date: 2016-06-15T20:14:47Z [Term] id: GO:1905269 name: positive regulation of chromatin organization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of chromatin organization." [GO_REF:0000058, GOC:pr, GOC:TermGenie, GOC:vw, PMID:654321] synonym: "positive regulation of chromatin organisation" EXACT [GOC:TermGenie] synonym: "positive regulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] synonym: "up regulation of chromatin organisation" EXACT [GOC:TermGenie] synonym: "up regulation of chromatin organization" EXACT [GOC:TermGenie] synonym: "up regulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] synonym: "up-regulation of chromatin organisation" EXACT [GOC:TermGenie] synonym: "up-regulation of chromatin organization" EXACT [GOC:TermGenie] synonym: "up-regulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] synonym: "upregulation of chromatin assembly or disassembly" EXACT [] synonym: "upregulation of chromatin organisation" EXACT [GOC:TermGenie] synonym: "upregulation of chromatin organization" EXACT [GOC:TermGenie] synonym: "upregulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] is_a: GO:1902275 ! regulation of chromatin organization is_a: GO:2001252 ! positive regulation of chromosome organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006325 ! positively regulates chromatin organization relationship: RO:0002213 GO:0006325 ! positively regulates chromatin organization creation_date: 2016-06-15T20:14:56Z [Term] id: GO:1905276 name: regulation of epithelial tube formation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of epithelial tube formation." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:25745997] is_a: GO:1905330 ! regulation of morphogenesis of an epithelium is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0072175 ! regulates (processual) epithelial tube formation relationship: RO:0002211 GO:0072175 ! regulates (processual) epithelial tube formation creation_date: 2016-06-20T09:35:41Z [Term] id: GO:1905277 name: negative regulation of epithelial tube formation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of epithelial tube formation." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:25745997] synonym: "down regulation of epithelial tube formation" EXACT [GOC:TermGenie] synonym: "down-regulation of epithelial tube formation" EXACT [GOC:TermGenie] synonym: "downregulation of epithelial tube formation" EXACT [GOC:TermGenie] is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1905276 ! regulation of epithelial tube formation is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0072175 ! negatively regulates epithelial tube formation relationship: RO:0002212 GO:0072175 ! negatively regulates epithelial tube formation creation_date: 2016-06-20T09:35:49Z [Term] id: GO:1905278 name: positive regulation of epithelial tube formation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of epithelial tube formation." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:25745997] synonym: "up regulation of epithelial tube formation" EXACT [GOC:TermGenie] synonym: "up-regulation of epithelial tube formation" EXACT [GOC:TermGenie] synonym: "upregulation of epithelial tube formation" EXACT [GOC:TermGenie] is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1905276 ! regulation of epithelial tube formation is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0072175 ! positively regulates epithelial tube formation relationship: RO:0002213 GO:0072175 ! positively regulates epithelial tube formation creation_date: 2016-06-20T09:35:57Z [Term] id: GO:1905288 name: vascular associated smooth muscle cell apoptotic process namespace: biological_process def: "Any apoptotic process in a vascular associated smooth muscle cell." [GO_REF:0000085, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:26493107] synonym: "vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "VSMC apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0034390 ! smooth muscle cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000359 ! occurs in vascular associated smooth muscle cell relationship: BFO:0000066 CL:0000359 ! occurs in vascular associated smooth muscle cell creation_date: 2016-06-23T13:24:20Z [Term] id: GO:1905292 name: regulation of neural crest cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of neural crest cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:15073157] is_a: GO:2000736 ! regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0014033 ! regulates (processual) neural crest cell differentiation relationship: RO:0002211 GO:0014033 ! regulates (processual) neural crest cell differentiation creation_date: 2016-06-28T15:02:01Z [Term] id: GO:1905293 name: negative regulation of neural crest cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of neural crest cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:15073157] synonym: "down regulation of neural crest cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of neural crest cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of neural crest cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1905292 ! regulation of neural crest cell differentiation is_a: GO:2000737 ! negative regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0014033 ! negatively regulates neural crest cell differentiation relationship: RO:0002212 GO:0014033 ! negatively regulates neural crest cell differentiation creation_date: 2016-06-28T15:02:09Z [Term] id: GO:1905294 name: positive regulation of neural crest cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of neural crest cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:15073157] synonym: "up regulation of neural crest cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of neural crest cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of neural crest cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1905292 ! regulation of neural crest cell differentiation is_a: GO:2000738 ! positive regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0014033 ! positively regulates neural crest cell differentiation relationship: RO:0002213 GO:0014033 ! positively regulates neural crest cell differentiation creation_date: 2016-06-28T15:02:16Z [Term] id: GO:1905298 name: regulation of intestinal epithelial cell development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of intestinal epithelial cell development." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23904268] is_a: GO:0030856 ! regulation of epithelial cell differentiation is_a: GO:0060284 ! regulation of cell development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060576 ! regulates (processual) intestinal epithelial cell development relationship: RO:0002211 GO:0060576 ! regulates (processual) intestinal epithelial cell development creation_date: 2016-06-30T11:40:47Z [Term] id: GO:1905299 name: negative regulation of intestinal epithelial cell development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of intestinal epithelial cell development." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23904268] synonym: "down regulation of intestinal epithelial cell development" EXACT [GOC:TermGenie] synonym: "down-regulation of intestinal epithelial cell development" EXACT [GOC:TermGenie] synonym: "downregulation of intestinal epithelial cell development" EXACT [GOC:TermGenie] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0030857 ! negative regulation of epithelial cell differentiation is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1905298 ! regulation of intestinal epithelial cell development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060576 ! negatively regulates intestinal epithelial cell development relationship: RO:0002212 GO:0060576 ! negatively regulates intestinal epithelial cell development creation_date: 2016-06-30T11:40:55Z [Term] id: GO:1905300 name: positive regulation of intestinal epithelial cell development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of intestinal epithelial cell development." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23904268] synonym: "up regulation of intestinal epithelial cell development" EXACT [GOC:TermGenie] synonym: "up-regulation of intestinal epithelial cell development" EXACT [GOC:TermGenie] synonym: "upregulation of intestinal epithelial cell development" EXACT [GOC:TermGenie] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1905298 ! regulation of intestinal epithelial cell development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060576 ! positively regulates intestinal epithelial cell development relationship: RO:0002213 GO:0060576 ! positively regulates intestinal epithelial cell development creation_date: 2016-06-30T11:41:02Z [Term] id: GO:1905304 name: regulation of cardiac myofibril assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac myofibril assembly." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:16151019] synonym: "regulation of cardiac myofibril development" EXACT [GOC:TermGenie] synonym: "regulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0060284 ! regulation of cell development is_a: GO:0110020 ! regulation of actomyosin structure organization is_a: GO:1902115 ! regulation of organelle assembly is_a: GO:1902903 ! regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0055003 ! regulates (processual) cardiac myofibril assembly relationship: RO:0002211 GO:0055003 ! regulates (processual) cardiac myofibril assembly creation_date: 2016-07-06T10:01:49Z [Term] id: GO:1905305 name: negative regulation of cardiac myofibril assembly namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac myofibril assembly." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:16151019] synonym: "down regulation of cardiac myofibril assembly" EXACT [GOC:TermGenie] synonym: "down regulation of cardiac myofibril development" EXACT [GOC:TermGenie] synonym: "down regulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of cardiac myofibril assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of cardiac myofibril development" EXACT [GOC:TermGenie] synonym: "down-regulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of cardiac myofibril assembly" EXACT [GOC:TermGenie] synonym: "downregulation of cardiac myofibril development" EXACT [GOC:TermGenie] synonym: "downregulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] synonym: "negative regulation of cardiac myofibril development" EXACT [GOC:TermGenie] synonym: "negative regulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0051494 ! negative regulation of cytoskeleton organization is_a: GO:1902116 ! negative regulation of organelle assembly is_a: GO:1902904 ! negative regulation of supramolecular fiber organization is_a: GO:1905304 ! regulation of cardiac myofibril assembly is_a: GO:2000726 ! negative regulation of cardiac muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0055003 ! negatively regulates cardiac myofibril assembly relationship: RO:0002212 GO:0055003 ! negatively regulates cardiac myofibril assembly creation_date: 2016-07-06T10:01:58Z [Term] id: GO:1905306 name: positive regulation of cardiac myofibril assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cardiac myofibril assembly." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:16151019] synonym: "positive regulation of cardiac myofibril development" EXACT [GOC:TermGenie] synonym: "positive regulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of cardiac myofibril assembly" EXACT [GOC:TermGenie] synonym: "up regulation of cardiac myofibril development" EXACT [GOC:TermGenie] synonym: "up regulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of cardiac myofibril assembly" EXACT [GOC:TermGenie] synonym: "up-regulation of cardiac myofibril development" EXACT [GOC:TermGenie] synonym: "up-regulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of cardiac myofibril assembly" EXACT [GOC:TermGenie] synonym: "upregulation of cardiac myofibril development" EXACT [GOC:TermGenie] synonym: "upregulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051495 ! positive regulation of cytoskeleton organization is_a: GO:1902117 ! positive regulation of organelle assembly is_a: GO:1902905 ! positive regulation of supramolecular fiber organization is_a: GO:1905304 ! regulation of cardiac myofibril assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0055003 ! positively regulates cardiac myofibril assembly relationship: RO:0002213 GO:0055003 ! positively regulates cardiac myofibril assembly creation_date: 2016-07-06T10:02:07Z [Term] id: GO:1905310 name: regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:17628518] is_a: GO:0030334 ! regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003253 ! regulates (processual) cardiac neural crest cell migration involved in outflow tract morphogenesis relationship: RO:0002211 GO:0003253 ! regulates (processual) cardiac neural crest cell migration involved in outflow tract morphogenesis creation_date: 2016-07-11T17:34:26Z [Term] id: GO:1905311 name: negative regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:17628518] synonym: "down regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of cardiac neural crest cell migration involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0030336 ! negative regulation of cell migration is_a: GO:1905310 ! regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0003253 ! negatively regulates cardiac neural crest cell migration involved in outflow tract morphogenesis relationship: RO:0002212 GO:0003253 ! negatively regulates cardiac neural crest cell migration involved in outflow tract morphogenesis creation_date: 2016-07-11T17:34:35Z [Term] id: GO:1905312 name: positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:17628518] synonym: "up regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of cardiac neural crest cell migration involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0030335 ! positive regulation of cell migration is_a: GO:1905310 ! regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0003253 ! positively regulates cardiac neural crest cell migration involved in outflow tract morphogenesis relationship: RO:0002213 GO:0003253 ! positively regulates cardiac neural crest cell migration involved in outflow tract morphogenesis creation_date: 2016-07-11T17:34:43Z [Term] id: GO:1905315 name: cell proliferation involved in endocardial cushion morphogenesis namespace: biological_process def: "Any cell proliferation that is involved in endocardial cushion morphogenesis." [GO_REF:0000060, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:20652948] is_a: GO:0061323 ! cell proliferation involved in heart morphogenesis intersection_of: GO:0008283 ! cell population proliferation intersection_of: BFO:0000050 GO:0003203 ! part of endocardial cushion morphogenesis relationship: BFO:0000050 GO:0003203 ! part of endocardial cushion morphogenesis creation_date: 2016-07-12T13:56:36Z [Term] id: GO:1905319 name: mesenchymal stem cell migration namespace: biological_process def: "The orderly movement of a mesenchymal stem cell from one site to another." [GO_REF:0000091, GOC:TermGenie, PMID:24924806, PMID:25181476] is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000134 ! results in movement of mesenchymal stem cell relationship: RO:0002565 CL:0000134 ! results in movement of mesenchymal stem cell creation_date: 2016-07-14T17:13:02Z [Term] id: GO:1905320 name: regulation of mesenchymal stem cell migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mesenchymal stem cell migration." [GO_REF:0000058, GOC:TermGenie, PMID:26846297] is_a: GO:0030334 ! regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1905319 ! regulates (processual) mesenchymal stem cell migration relationship: RO:0002211 GO:1905319 ! regulates (processual) mesenchymal stem cell migration creation_date: 2016-07-15T22:19:14Z [Term] id: GO:1905321 name: negative regulation of mesenchymal stem cell migration namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell migration." [GO_REF:0000058, GOC:TermGenie, PMID:26846297] synonym: "down regulation of mesenchymal stem cell migration" EXACT [GOC:TermGenie] synonym: "down-regulation of mesenchymal stem cell migration" EXACT [GOC:TermGenie] synonym: "downregulation of mesenchymal stem cell migration" EXACT [GOC:TermGenie] is_a: GO:0030336 ! negative regulation of cell migration is_a: GO:1905320 ! regulation of mesenchymal stem cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1905319 ! negatively regulates mesenchymal stem cell migration relationship: RO:0002212 GO:1905319 ! negatively regulates mesenchymal stem cell migration creation_date: 2016-07-15T22:19:22Z [Term] id: GO:1905322 name: positive regulation of mesenchymal stem cell migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell migration." [GO_REF:0000058, GOC:TermGenie, PMID:26846297] synonym: "up regulation of mesenchymal stem cell migration" EXACT [GOC:TermGenie] synonym: "up-regulation of mesenchymal stem cell migration" EXACT [GOC:TermGenie] synonym: "upregulation of mesenchymal stem cell migration" EXACT [GOC:TermGenie] is_a: GO:0030335 ! positive regulation of cell migration is_a: GO:1905320 ! regulation of mesenchymal stem cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1905319 ! positively regulates mesenchymal stem cell migration relationship: RO:0002213 GO:1905319 ! positively regulates mesenchymal stem cell migration creation_date: 2016-07-15T22:19:29Z [Term] id: GO:1905330 name: regulation of morphogenesis of an epithelium namespace: biological_process def: "Any process that modulates the frequency, rate or extent of morphogenesis of an epithelium." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:25745997] synonym: "regulation of epithelium morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002009 ! regulates (processual) morphogenesis of an epithelium relationship: RO:0002211 GO:0002009 ! regulates (processual) morphogenesis of an epithelium creation_date: 2016-07-22T07:13:49Z [Term] id: GO:1905331 name: negative regulation of morphogenesis of an epithelium namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of morphogenesis of an epithelium." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:25745997] synonym: "down regulation of epithelium morphogenesis" EXACT [GOC:TermGenie] synonym: "down regulation of morphogenesis of an epithelium" EXACT [GOC:TermGenie] synonym: "down-regulation of epithelium morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of morphogenesis of an epithelium" EXACT [GOC:TermGenie] synonym: "downregulation of epithelium morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of morphogenesis of an epithelium" EXACT [GOC:TermGenie] synonym: "negative regulation of epithelium morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:1905330 ! regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002009 ! negatively regulates morphogenesis of an epithelium relationship: RO:0002212 GO:0002009 ! negatively regulates morphogenesis of an epithelium creation_date: 2016-07-22T07:13:57Z [Term] id: GO:1905332 name: positive regulation of morphogenesis of an epithelium namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of morphogenesis of an epithelium." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:25745997] synonym: "positive regulation of epithelium morphogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of epithelium morphogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of morphogenesis of an epithelium" EXACT [GOC:TermGenie] synonym: "up-regulation of epithelium morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of morphogenesis of an epithelium" EXACT [GOC:TermGenie] synonym: "upregulation of epithelium morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of morphogenesis of an epithelium" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:1905330 ! regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002009 ! positively regulates morphogenesis of an epithelium relationship: RO:0002213 GO:0002009 ! positively regulates morphogenesis of an epithelium creation_date: 2016-07-22T07:14:05Z [Term] id: GO:1905349 name: ciliary transition zone assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form a ciliary transition zone." [GO_REF:0000079, GOC:cilia, GOC:TermGenie, PMID:21725307, PMID:23644468, PMID:24448408, PMID:26595381, PMID:26982032] synonym: "cilial transition zone assembly" EXACT [GOC:TermGenie] synonym: "cilial transition zone formation" EXACT [GOC:TermGenie] synonym: "ciliary transition zone formation" EXACT [GOC:TermGenie] synonym: "cilium transition zone assembly" EXACT [GOC:TermGenie] synonym: "cilium transition zone formation" EXACT [GOC:TermGenie] is_a: GO:0022607 ! cellular component assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0035869 ! results in assembly of ciliary transition zone relationship: BFO:0000050 GO:0060271 ! part of cilium assembly relationship: RO:0002588 GO:0035869 ! results in assembly of ciliary transition zone creation_date: 2016-08-04T14:49:43Z [Term] id: GO:1905383 name: protein localization to presynapse namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within a presynapse." [GO_REF:0000087, GOC:TermGenie, PMID:24449494] synonym: "protein localisation in presynapse" EXACT [GOC:TermGenie] synonym: "protein localisation to presynapse" EXACT [GOC:TermGenie] synonym: "protein localization in presynapse" EXACT [GOC:TermGenie] synonym: "recruitment of presynaptic proteins" EXACT [PMID:24449494] is_a: GO:0035418 ! protein localization to synapse intersection_of: GO:0008104 ! protein localization intersection_of: RO:0002339 GO:0098793 ! has target end location presynapse relationship: RO:0002339 GO:0098793 ! has target end location presynapse creation_date: 2016-08-18T14:42:59Z [Term] id: GO:1905384 name: regulation of protein localization to presynapse namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein localization to presynapse." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24449494] synonym: "regulation of protein localisation in presynapse" EXACT [GOC:TermGenie] synonym: "regulation of protein localisation to presynapse" EXACT [GOC:TermGenie] synonym: "regulation of protein localization in presynapse" EXACT [GOC:TermGenie] synonym: "regulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] is_a: GO:1902473 ! regulation of protein localization to synapse intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1905383 ! regulates (processual) protein localization to presynapse relationship: RO:0002211 GO:1905383 ! regulates (processual) protein localization to presynapse creation_date: 2016-08-18T14:56:00Z [Term] id: GO:1905385 name: negative regulation of protein localization to presynapse namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to presynapse." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24449494] synonym: "down regulation of protein localisation in presynapse" EXACT [GOC:TermGenie] synonym: "down regulation of protein localisation to presynapse" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization in presynapse" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization to presynapse" EXACT [GOC:TermGenie] synonym: "down regulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation in presynapse" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation to presynapse" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization in presynapse" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to presynapse" EXACT [GOC:TermGenie] synonym: "down-regulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation in presynapse" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation to presynapse" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization in presynapse" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to presynapse" EXACT [GOC:TermGenie] synonym: "downregulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localisation in presynapse" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localisation to presynapse" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localization in presynapse" EXACT [GOC:TermGenie] synonym: "negative regulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] is_a: GO:1903828 ! negative regulation of protein localization is_a: GO:1905384 ! regulation of protein localization to presynapse intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1905383 ! negatively regulates protein localization to presynapse relationship: RO:0002212 GO:1905383 ! negatively regulates protein localization to presynapse creation_date: 2016-08-18T14:56:08Z [Term] id: GO:1905386 name: positive regulation of protein localization to presynapse namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein localization to presynapse." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24449494] synonym: "positive regulation of protein localisation in presynapse" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localisation to presynapse" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localization in presynapse" EXACT [GOC:TermGenie] synonym: "positive regulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation in presynapse" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation to presynapse" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization in presynapse" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization to presynapse" EXACT [GOC:TermGenie] synonym: "up regulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation in presynapse" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation to presynapse" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization in presynapse" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to presynapse" EXACT [GOC:TermGenie] synonym: "up-regulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation in presynapse" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation to presynapse" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization in presynapse" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to presynapse" EXACT [GOC:TermGenie] synonym: "upregulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] is_a: GO:1902474 ! positive regulation of protein localization to synapse is_a: GO:1905384 ! regulation of protein localization to presynapse intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1905383 ! positively regulates protein localization to presynapse relationship: RO:0002213 GO:1905383 ! positively regulates protein localization to presynapse creation_date: 2016-08-18T14:56:21Z [Term] id: GO:1905432 name: regulation of retrograde trans-synaptic signaling by neuropeptide namespace: biological_process def: "Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:19448629] is_a: GO:0099177 ! regulation of trans-synaptic signaling intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0099082 ! regulates (processual) retrograde trans-synaptic signaling by neuropeptide relationship: RO:0002211 GO:0099082 ! regulates (processual) retrograde trans-synaptic signaling by neuropeptide creation_date: 2016-09-14T10:56:47Z [Term] id: GO:1905433 name: negative regulation of retrograde trans-synaptic signaling by neuropeptide namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:19448629] synonym: "down regulation of retrograde trans-synaptic signaling by neuropeptide" EXACT [GOC:TermGenie] synonym: "down-regulation of retrograde trans-synaptic signaling by neuropeptide" EXACT [GOC:TermGenie] synonym: "downregulation of retrograde trans-synaptic signaling by neuropeptide" EXACT [GOC:TermGenie] is_a: GO:0010648 ! negative regulation of cell communication is_a: GO:0023057 ! negative regulation of signaling is_a: GO:1905432 ! regulation of retrograde trans-synaptic signaling by neuropeptide intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0099082 ! negatively regulates retrograde trans-synaptic signaling by neuropeptide relationship: RO:0002212 GO:0099082 ! negatively regulates retrograde trans-synaptic signaling by neuropeptide creation_date: 2016-09-14T10:56:55Z [Term] id: GO:1905434 name: positive regulation of retrograde trans-synaptic signaling by neuropeptide namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:19448629] synonym: "up regulation of retrograde trans-synaptic signaling by neuropeptide" EXACT [GOC:TermGenie] synonym: "up-regulation of retrograde trans-synaptic signaling by neuropeptide" EXACT [GOC:TermGenie] synonym: "upregulation of retrograde trans-synaptic signaling by neuropeptide" EXACT [GOC:TermGenie] is_a: GO:0010647 ! positive regulation of cell communication is_a: GO:0023056 ! positive regulation of signaling is_a: GO:1905432 ! regulation of retrograde trans-synaptic signaling by neuropeptide intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0099082 ! positively regulates retrograde trans-synaptic signaling by neuropeptide relationship: RO:0002213 GO:0099082 ! positively regulates retrograde trans-synaptic signaling by neuropeptide creation_date: 2016-09-14T10:57:02Z [Term] id: GO:1905453 name: regulation of myeloid progenitor cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of myeloid progenitor cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:27010503] is_a: GO:1901532 ! regulation of hematopoietic progenitor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002318 ! regulates (processual) myeloid progenitor cell differentiation relationship: RO:0002211 GO:0002318 ! regulates (processual) myeloid progenitor cell differentiation creation_date: 2016-09-16T12:32:18Z [Term] id: GO:1905454 name: negative regulation of myeloid progenitor cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of myeloid progenitor cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:27010503] synonym: "down regulation of myeloid progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of myeloid progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of myeloid progenitor cell differentiation" EXACT [GOC:TermGenie] is_a: GO:1901533 ! negative regulation of hematopoietic progenitor cell differentiation is_a: GO:1905453 ! regulation of myeloid progenitor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002318 ! negatively regulates myeloid progenitor cell differentiation relationship: RO:0002212 GO:0002318 ! negatively regulates myeloid progenitor cell differentiation creation_date: 2016-09-16T12:32:26Z [Term] id: GO:1905455 name: positive regulation of myeloid progenitor cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of myeloid progenitor cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:27010503] synonym: "up regulation of myeloid progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of myeloid progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of myeloid progenitor cell differentiation" EXACT [GOC:TermGenie] is_a: GO:1901534 ! positive regulation of hematopoietic progenitor cell differentiation is_a: GO:1905453 ! regulation of myeloid progenitor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002318 ! positively regulates myeloid progenitor cell differentiation relationship: RO:0002213 GO:0002318 ! positively regulates myeloid progenitor cell differentiation creation_date: 2016-09-16T12:32:33Z [Term] id: GO:1905456 name: regulation of lymphoid progenitor cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of lymphoid progenitor cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:27010503] is_a: GO:1901532 ! regulation of hematopoietic progenitor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002320 ! regulates (processual) lymphoid progenitor cell differentiation relationship: RO:0002211 GO:0002320 ! regulates (processual) lymphoid progenitor cell differentiation creation_date: 2016-09-16T12:32:40Z [Term] id: GO:1905457 name: negative regulation of lymphoid progenitor cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of lymphoid progenitor cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:27010503] synonym: "down regulation of lymphoid progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of lymphoid progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of lymphoid progenitor cell differentiation" EXACT [GOC:TermGenie] is_a: GO:1901533 ! negative regulation of hematopoietic progenitor cell differentiation is_a: GO:1905456 ! regulation of lymphoid progenitor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002320 ! negatively regulates lymphoid progenitor cell differentiation relationship: RO:0002212 GO:0002320 ! negatively regulates lymphoid progenitor cell differentiation creation_date: 2016-09-16T12:32:48Z [Term] id: GO:1905458 name: positive regulation of lymphoid progenitor cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of lymphoid progenitor cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:27010503] synonym: "up regulation of lymphoid progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of lymphoid progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of lymphoid progenitor cell differentiation" EXACT [GOC:TermGenie] is_a: GO:1901534 ! positive regulation of hematopoietic progenitor cell differentiation is_a: GO:1905456 ! regulation of lymphoid progenitor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002320 ! positively regulates lymphoid progenitor cell differentiation relationship: RO:0002213 GO:0002320 ! positively regulates lymphoid progenitor cell differentiation creation_date: 2016-09-16T12:32:55Z [Term] id: GO:1905459 name: regulation of vascular associated smooth muscle cell apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:26493107] synonym: "regulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "regulation of VSMC apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0034391 ! regulation of smooth muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1905288 ! regulates (processual) vascular associated smooth muscle cell apoptotic process relationship: RO:0002211 GO:1905288 ! regulates (processual) vascular associated smooth muscle cell apoptotic process creation_date: 2016-09-19T11:33:54Z [Term] id: GO:1905460 name: negative regulation of vascular associated smooth muscle cell apoptotic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:26493107] synonym: "down regulation of vascular associated smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down regulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down regulation of VSMC apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of vascular associated smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of VSMC apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of vascular associated smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of VSMC apoptotic process" EXACT [GOC:TermGenie] synonym: "negative regulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "negative regulation of VSMC apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0034392 ! negative regulation of smooth muscle cell apoptotic process is_a: GO:1905459 ! regulation of vascular associated smooth muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1905288 ! negatively regulates vascular associated smooth muscle cell apoptotic process relationship: RO:0002212 GO:1905288 ! negatively regulates vascular associated smooth muscle cell apoptotic process creation_date: 2016-09-19T11:34:03Z [Term] id: GO:1905461 name: positive regulation of vascular associated smooth muscle cell apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:26493107] synonym: "positive regulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "positive regulation of VSMC apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of vascular associated smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of VSMC apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of vascular associated smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of VSMC apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of vascular associated smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of VSMC apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0034393 ! positive regulation of smooth muscle cell apoptotic process is_a: GO:1905459 ! regulation of vascular associated smooth muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1905288 ! positively regulates vascular associated smooth muscle cell apoptotic process relationship: RO:0002213 GO:1905288 ! positively regulates vascular associated smooth muscle cell apoptotic process creation_date: 2016-09-19T11:34:10Z [Term] id: GO:1905475 name: regulation of protein localization to membrane namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein localization to membrane." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:26911690] synonym: "regulation of protein localisation in membrane" EXACT [GOC:TermGenie] synonym: "regulation of protein localization in membrane" EXACT [GOC:TermGenie] is_a: GO:0032880 ! regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0072657 ! regulates (processual) protein localization to membrane relationship: RO:0002211 GO:0072657 ! regulates (processual) protein localization to membrane creation_date: 2016-09-21T16:20:03Z [Term] id: GO:1905476 name: negative regulation of protein localization to membrane namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to membrane." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:26911690] synonym: "down regulation of protein localisation in membrane" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization in membrane" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization to membrane" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation in membrane" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization in membrane" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to membrane" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation in membrane" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization in membrane" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to membrane" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localisation in membrane" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localization in membrane" EXACT [GOC:TermGenie] is_a: GO:1903828 ! negative regulation of protein localization is_a: GO:1905475 ! regulation of protein localization to membrane intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0072657 ! negatively regulates protein localization to membrane relationship: RO:0002212 GO:0072657 ! negatively regulates protein localization to membrane creation_date: 2016-09-21T16:20:10Z [Term] id: GO:1905477 name: positive regulation of protein localization to membrane namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein localization to membrane." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:26911690] synonym: "positive regulation of protein localisation in membrane" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localization in membrane" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation in membrane" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization in membrane" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization to membrane" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation in membrane" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization in membrane" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to membrane" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation in membrane" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization in membrane" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to membrane" EXACT [GOC:TermGenie] is_a: GO:1903829 ! positive regulation of protein localization is_a: GO:1905475 ! regulation of protein localization to membrane intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0072657 ! positively regulates protein localization to membrane relationship: RO:0002213 GO:0072657 ! positively regulates protein localization to membrane creation_date: 2016-09-21T16:20:18Z [Term] id: GO:1905483 name: regulation of motor neuron migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of motor neuron migration." [GO_REF:0000058, GOC:TermGenie, PMID:16516839] is_a: GO:2001222 ! regulation of neuron migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0097475 ! regulates (processual) motor neuron migration relationship: RO:0002211 GO:0097475 ! regulates (processual) motor neuron migration creation_date: 2016-09-23T12:49:54Z [Term] id: GO:1905484 name: negative regulation of motor neuron migration namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron migration." [GO_REF:0000058, GOC:TermGenie, PMID:16516839] synonym: "down regulation of motor neuron migration" EXACT [GOC:TermGenie] synonym: "down-regulation of motor neuron migration" EXACT [GOC:TermGenie] synonym: "downregulation of motor neuron migration" EXACT [GOC:TermGenie] is_a: GO:1905483 ! regulation of motor neuron migration is_a: GO:2001223 ! negative regulation of neuron migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0097475 ! negatively regulates motor neuron migration relationship: RO:0002212 GO:0097475 ! negatively regulates motor neuron migration creation_date: 2016-09-23T12:50:11Z [Term] id: GO:1905485 name: positive regulation of motor neuron migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of motor neuron migration." [GO_REF:0000058, GOC:TermGenie, PMID:16516839] synonym: "up regulation of motor neuron migration" EXACT [GOC:TermGenie] synonym: "up-regulation of motor neuron migration" EXACT [GOC:TermGenie] synonym: "upregulation of motor neuron migration" EXACT [GOC:TermGenie] is_a: GO:1905483 ! regulation of motor neuron migration is_a: GO:2001224 ! positive regulation of neuron migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0097475 ! positively regulates motor neuron migration relationship: RO:0002213 GO:0097475 ! positively regulates motor neuron migration creation_date: 2016-09-23T12:50:19Z [Term] id: GO:1905492 name: positive regulation of branching morphogenesis of a nerve namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of branching morphogenesis of a nerve." [GO_REF:0000058, GOC:TermGenie, PMID:16516839] synonym: "up regulation of branching morphogenesis of a nerve" EXACT [GOC:TermGenie] synonym: "up-regulation of branching morphogenesis of a nerve" EXACT [GOC:TermGenie] synonym: "upregulation of branching morphogenesis of a nerve" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:2000172 ! regulation of branching morphogenesis of a nerve intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0048755 ! positively regulates branching morphogenesis of a nerve relationship: RO:0002213 GO:0048755 ! positively regulates branching morphogenesis of a nerve creation_date: 2016-09-23T14:11:52Z [Term] id: GO:1905503 name: regulation of motile cilium assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of motile cilium assembly." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:25294941] is_a: GO:1902017 ! regulation of cilium assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0044458 ! regulates (processual) motile cilium assembly relationship: RO:0002211 GO:0044458 ! regulates (processual) motile cilium assembly creation_date: 2016-09-27T18:27:47Z [Term] id: GO:1905504 name: negative regulation of motile cilium assembly namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of motile cilium assembly." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:25294941] is_a: GO:1902018 ! negative regulation of cilium assembly is_a: GO:1905503 ! regulation of motile cilium assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0044458 ! negatively regulates motile cilium assembly relationship: RO:0002212 GO:0044458 ! negatively regulates motile cilium assembly creation_date: 2016-09-27T18:27:55Z [Term] id: GO:1905505 name: positive regulation of motile cilium assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of motile cilium assembly." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:25294941] is_a: GO:0045724 ! positive regulation of cilium assembly is_a: GO:1905503 ! regulation of motile cilium assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0044458 ! positively regulates motile cilium assembly relationship: RO:0002213 GO:0044458 ! positively regulates motile cilium assembly creation_date: 2016-09-27T18:28:03Z [Term] id: GO:1905516 name: positive regulation of fertilization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of fertilization." [GO_REF:0000058, GOC:hbye, GOC:TermGenie, PMID:27564576] synonym: "positive regulation of syngamy" EXACT [GOC:TermGenie] synonym: "up regulation of fertilization" EXACT [GOC:TermGenie] synonym: "up regulation of syngamy" EXACT [GOC:TermGenie] synonym: "up-regulation of fertilization" EXACT [GOC:TermGenie] synonym: "up-regulation of syngamy" EXACT [GOC:TermGenie] synonym: "upregulation of fertilization" EXACT [GOC:TermGenie] synonym: "upregulation of syngamy" EXACT [GOC:TermGenie] is_a: GO:0080154 ! regulation of fertilization is_a: GO:2000243 ! positive regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0009566 ! positively regulates fertilization relationship: RO:0002213 GO:0009566 ! positively regulates fertilization creation_date: 2016-09-30T14:32:32Z [Term] id: GO:1905553 name: regulation of blood vessel branching namespace: biological_process def: "Any process that modulates the frequency, rate or extent of blood vessel branching." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23201774] synonym: "regulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0045765 ! regulation of angiogenesis is_a: GO:0060688 ! regulation of morphogenesis of a branching structure is_a: GO:1905330 ! regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001569 ! regulates (processual) branching involved in blood vessel morphogenesis relationship: RO:0002211 GO:0001569 ! regulates (processual) branching involved in blood vessel morphogenesis creation_date: 2016-10-12T14:19:33Z [Term] id: GO:1905554 name: negative regulation of vessel branching namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of blood vessel branching." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23201774] synonym: "down regulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] synonym: "down regulation of patterning of blood vessels" EXACT [GOC:TermGenie] synonym: "down-regulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of patterning of blood vessels" EXACT [GOC:TermGenie] synonym: "downregulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of patterning of blood vessels" EXACT [GOC:TermGenie] synonym: "negative regulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0016525 ! negative regulation of angiogenesis is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium is_a: GO:1905553 ! regulation of blood vessel branching intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001569 ! negatively regulates branching involved in blood vessel morphogenesis relationship: RO:0002212 GO:0001569 ! negatively regulates branching involved in blood vessel morphogenesis creation_date: 2016-10-12T14:19:41Z [Term] id: GO:1905555 name: positive regulation of blood vessel branching namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of blood vessel branching." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23201774] synonym: "positive regulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of patterning of blood vessels" EXACT [GOC:TermGenie] synonym: "up-regulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of patterning of blood vessels" EXACT [GOC:TermGenie] synonym: "upregulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of patterning of blood vessels" EXACT [GOC:TermGenie] is_a: GO:0045766 ! positive regulation of angiogenesis is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium is_a: GO:1905553 ! regulation of blood vessel branching intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001569 ! positively regulates branching involved in blood vessel morphogenesis relationship: RO:0002213 GO:0001569 ! positively regulates branching involved in blood vessel morphogenesis creation_date: 2016-10-12T14:19:49Z [Term] id: GO:1905557 name: regulation of mitotic nuclear envelope disassembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mitotic nuclear envelope disassembly." [GO_REF:0000058, GOC:TermGenie, PMID:18765790] synonym: "regulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] synonym: "regulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] synonym: "regulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] is_a: GO:0010549 ! regulation of membrane disassembly is_a: GO:0010564 ! regulation of cell cycle process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007077 ! regulates (processual) mitotic nuclear membrane disassembly relationship: RO:0002211 GO:0007077 ! regulates (processual) mitotic nuclear membrane disassembly creation_date: 2016-10-14T13:14:57Z [Term] id: GO:1905558 name: negative regulation of mitotic nuclear envelope disassembly namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic nuclear envelope disassembly." [GO_REF:0000058, GOC:TermGenie, PMID:18765790] synonym: "down regulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] synonym: "down regulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] synonym: "down regulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] synonym: "down regulation of mitotic nuclear envelope disassembly" EXACT [GOC:TermGenie] synonym: "down-regulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] synonym: "down-regulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] synonym: "down-regulation of mitotic nuclear envelope disassembly" EXACT [GOC:TermGenie] synonym: "downregulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] synonym: "downregulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] synonym: "downregulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] synonym: "downregulation of mitotic nuclear envelope disassembly" EXACT [GOC:TermGenie] synonym: "negative regulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] synonym: "negative regulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] is_a: GO:0010948 ! negative regulation of cell cycle process is_a: GO:0051129 ! negative regulation of cellular component organization is_a: GO:1905557 ! regulation of mitotic nuclear envelope disassembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007077 ! negatively regulates mitotic nuclear membrane disassembly relationship: RO:0002212 GO:0007077 ! negatively regulates mitotic nuclear membrane disassembly creation_date: 2016-10-14T13:15:08Z [Term] id: GO:1905559 name: positive regulation of mitotic nuclear envelope disassembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mitotic nuclear envelope disassembly." [GO_REF:0000058, GOC:TermGenie, PMID:18765790] synonym: "positive regulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] synonym: "positive regulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] synonym: "up regulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] synonym: "up regulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] synonym: "up regulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] synonym: "up regulation of mitotic nuclear envelope disassembly" EXACT [GOC:TermGenie] synonym: "up-regulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] synonym: "up-regulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] synonym: "up-regulation of mitotic nuclear envelope disassembly" EXACT [GOC:TermGenie] synonym: "upregulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] synonym: "upregulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] synonym: "upregulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] synonym: "upregulation of mitotic nuclear envelope disassembly" EXACT [GOC:TermGenie] is_a: GO:0051130 ! positive regulation of cellular component organization is_a: GO:0090068 ! positive regulation of cell cycle process is_a: GO:1905557 ! regulation of mitotic nuclear envelope disassembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007077 ! positively regulates mitotic nuclear membrane disassembly relationship: RO:0002213 GO:0007077 ! positively regulates mitotic nuclear membrane disassembly creation_date: 2016-10-14T13:15:17Z [Term] id: GO:1905562 name: regulation of vascular endothelial cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of vascular endothelial cell proliferation." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23201774] is_a: GO:0001936 ! regulation of endothelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0101023 ! regulates (processual) vascular endothelial cell proliferation relationship: RO:0002211 GO:0101023 ! regulates (processual) vascular endothelial cell proliferation creation_date: 2016-10-17T09:24:17Z [Term] id: GO:1905563 name: negative regulation of vascular endothelial cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial cell proliferation." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23201774] synonym: "down regulation of vascular endothelial cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of vascular endothelial cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of vascular endothelial cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0001937 ! negative regulation of endothelial cell proliferation is_a: GO:1905562 ! regulation of vascular endothelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0101023 ! negatively regulates vascular endothelial cell proliferation relationship: RO:0002212 GO:0101023 ! negatively regulates vascular endothelial cell proliferation creation_date: 2016-10-17T09:24:26Z [Term] id: GO:1905564 name: positive regulation of vascular endothelial cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of vascular endothelial cell proliferation." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23201774] synonym: "up regulation of vascular endothelial cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of vascular endothelial cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of vascular endothelial cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0001938 ! positive regulation of endothelial cell proliferation is_a: GO:1905562 ! regulation of vascular endothelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0101023 ! positively regulates vascular endothelial cell proliferation relationship: RO:0002213 GO:0101023 ! positively regulates vascular endothelial cell proliferation creation_date: 2016-10-17T09:24:35Z [Term] id: GO:1905606 name: regulation of presynapse assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of presynapse assembly." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:25533483] synonym: "regulation of presynapse biogenesis" EXACT [GOC:TermGenie] synonym: "regulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] is_a: GO:0051963 ! regulation of synapse assembly is_a: GO:0099174 ! regulation of presynapse organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0099054 ! regulates (processual) presynapse assembly relationship: RO:0002211 GO:0099054 ! regulates (processual) presynapse assembly creation_date: 2016-10-27T16:08:13Z [Term] id: GO:1905607 name: negative regulation of presynapse assembly namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of presynapse assembly." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:25533483] synonym: "down regulation of presynapse assembly" EXACT [GOC:TermGenie] synonym: "down regulation of presynapse biogenesis" EXACT [GOC:TermGenie] synonym: "down regulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of presynapse assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of presynapse biogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] synonym: "downregulation of presynapse assembly" EXACT [GOC:TermGenie] synonym: "downregulation of presynapse biogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] synonym: "negative regulation of presynapse biogenesis" EXACT [GOC:TermGenie] synonym: "negative regulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] is_a: GO:0051964 ! negative regulation of synapse assembly is_a: GO:1905606 ! regulation of presynapse assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0099054 ! negatively regulates presynapse assembly relationship: RO:0002212 GO:0099054 ! negatively regulates presynapse assembly creation_date: 2016-10-27T16:08:20Z [Term] id: GO:1905608 name: positive regulation of presynapse assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of presynapse assembly." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:25533483] synonym: "positive regulation of presynapse biogenesis" EXACT [GOC:TermGenie] synonym: "positive regulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] synonym: "up regulation of presynapse assembly" EXACT [GOC:TermGenie] synonym: "up regulation of presynapse biogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] synonym: "up-regulation of presynapse assembly" EXACT [GOC:TermGenie] synonym: "up-regulation of presynapse biogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] synonym: "upregulation of presynapse assembly" EXACT [GOC:TermGenie] synonym: "upregulation of presynapse biogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] is_a: GO:0051130 ! positive regulation of cellular component organization is_a: GO:1905606 ! regulation of presynapse assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0099054 ! positively regulates presynapse assembly relationship: RO:0002213 GO:0099054 ! positively regulates presynapse assembly creation_date: 2016-10-27T16:08:28Z [Term] id: GO:1905627 name: regulation of serotonin biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of serotonin biosynthetic process." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:25642596] synonym: "regulation of serotonin anabolism" EXACT [GOC:TermGenie] synonym: "regulation of serotonin biosynthesis" EXACT [GOC:TermGenie] synonym: "regulation of serotonin formation" EXACT [GOC:TermGenie] synonym: "regulation of serotonin synthesis" EXACT [GOC:TermGenie] is_a: GO:0009889 ! regulation of biosynthetic process is_a: GO:0031323 ! regulation of cellular metabolic process is_a: GO:0051171 ! regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0042427 ! regulates (processual) serotonin biosynthetic process relationship: RO:0002211 GO:0042427 ! regulates (processual) serotonin biosynthetic process creation_date: 2016-10-31T14:26:20Z [Term] id: GO:1905628 name: negative regulation of serotonin biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of serotonin biosynthetic process." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:25642596] synonym: "down regulation of serotonin anabolism" EXACT [GOC:TermGenie] synonym: "down regulation of serotonin biosynthesis" EXACT [GOC:TermGenie] synonym: "down regulation of serotonin biosynthetic process" EXACT [GOC:TermGenie] synonym: "down regulation of serotonin formation" EXACT [GOC:TermGenie] synonym: "down regulation of serotonin synthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of serotonin anabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of serotonin biosynthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of serotonin biosynthetic process" EXACT [GOC:TermGenie] synonym: "down-regulation of serotonin formation" EXACT [GOC:TermGenie] synonym: "down-regulation of serotonin synthesis" EXACT [GOC:TermGenie] synonym: "downregulation of serotonin anabolism" EXACT [GOC:TermGenie] synonym: "downregulation of serotonin biosynthesis" EXACT [GOC:TermGenie] synonym: "downregulation of serotonin biosynthetic process" EXACT [GOC:TermGenie] synonym: "downregulation of serotonin formation" EXACT [GOC:TermGenie] synonym: "downregulation of serotonin synthesis" EXACT [GOC:TermGenie] synonym: "negative regulation of serotonin anabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of serotonin biosynthesis" EXACT [GOC:TermGenie] synonym: "negative regulation of serotonin formation" EXACT [GOC:TermGenie] synonym: "negative regulation of serotonin synthesis" EXACT [GOC:TermGenie] is_a: GO:0009890 ! negative regulation of biosynthetic process is_a: GO:0031324 ! negative regulation of cellular metabolic process is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process is_a: GO:1905627 ! regulation of serotonin biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0042427 ! negatively regulates serotonin biosynthetic process relationship: RO:0002212 GO:0042427 ! negatively regulates serotonin biosynthetic process creation_date: 2016-10-31T14:26:28Z [Term] id: GO:1905629 name: positive regulation of serotonin biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of serotonin biosynthetic process." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:25642596] synonym: "positive regulation of serotonin anabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of serotonin biosynthesis" EXACT [GOC:TermGenie] synonym: "positive regulation of serotonin formation" EXACT [GOC:TermGenie] synonym: "positive regulation of serotonin synthesis" EXACT [GOC:TermGenie] synonym: "up regulation of serotonin anabolism" EXACT [GOC:TermGenie] synonym: "up regulation of serotonin biosynthesis" EXACT [GOC:TermGenie] synonym: "up regulation of serotonin biosynthetic process" EXACT [GOC:TermGenie] synonym: "up regulation of serotonin formation" EXACT [GOC:TermGenie] synonym: "up regulation of serotonin synthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of serotonin anabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of serotonin biosynthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of serotonin biosynthetic process" EXACT [GOC:TermGenie] synonym: "up-regulation of serotonin formation" EXACT [GOC:TermGenie] synonym: "up-regulation of serotonin synthesis" EXACT [GOC:TermGenie] synonym: "upregulation of serotonin anabolism" EXACT [GOC:TermGenie] synonym: "upregulation of serotonin biosynthesis" EXACT [GOC:TermGenie] synonym: "upregulation of serotonin biosynthetic process" EXACT [GOC:TermGenie] synonym: "upregulation of serotonin formation" EXACT [GOC:TermGenie] synonym: "upregulation of serotonin synthesis" EXACT [GOC:TermGenie] is_a: GO:0009891 ! positive regulation of biosynthetic process is_a: GO:0031325 ! positive regulation of cellular metabolic process is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process is_a: GO:1905627 ! regulation of serotonin biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0042427 ! positively regulates serotonin biosynthetic process relationship: RO:0002213 GO:0042427 ! positively regulates serotonin biosynthetic process creation_date: 2016-10-31T14:26:36Z [Term] id: GO:1905634 name: regulation of protein localization to chromatin namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein localization to chromatin." [GO_REF:0000058, GOC:TermGenie, PMID:20889714] synonym: "regulation of protein localisation to chromatin" EXACT [GOC:TermGenie] is_a: GO:0032880 ! regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0071168 ! regulates (processual) protein localization to chromatin relationship: RO:0002211 GO:0071168 ! regulates (processual) protein localization to chromatin creation_date: 2016-11-01T16:33:52Z [Term] id: GO:1905651 name: regulation of artery morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of artery morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:27389411] synonym: "regulation of arterial morphogenesis" EXACT [GOC:TermGenie] synonym: "regulation of arteriogenesis" EXACT [GOC:TermGenie] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048844 ! regulates (processual) artery morphogenesis relationship: RO:0002211 GO:0048844 ! regulates (processual) artery morphogenesis creation_date: 2016-11-09T12:19:37Z [Term] id: GO:1905652 name: negative regulation of artery morphogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of artery morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:27389411] synonym: "down regulation of arterial morphogenesis" EXACT [GOC:TermGenie] synonym: "down regulation of arteriogenesis" EXACT [GOC:TermGenie] synonym: "down regulation of artery morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of arterial morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of arteriogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of artery morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of arterial morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of arteriogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of artery morphogenesis" EXACT [GOC:TermGenie] synonym: "negative regulation of arterial morphogenesis" EXACT [GOC:TermGenie] synonym: "negative regulation of arteriogenesis" EXACT [GOC:TermGenie] is_a: GO:1905651 ! regulation of artery morphogenesis is_a: GO:2000181 ! negative regulation of blood vessel morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048844 ! negatively regulates artery morphogenesis relationship: RO:0002212 GO:0048844 ! negatively regulates artery morphogenesis creation_date: 2016-11-09T12:19:53Z [Term] id: GO:1905653 name: positive regulation of artery morphogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of artery morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:27389411] synonym: "positive regulation of arterial morphogenesis" EXACT [GOC:TermGenie] synonym: "positive regulation of arteriogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of arterial morphogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of arteriogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of artery morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of arterial morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of arteriogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of artery morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of arterial morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of arteriogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of artery morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:1905651 ! regulation of artery morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0048844 ! positively regulates artery morphogenesis relationship: RO:0002213 GO:0048844 ! positively regulates artery morphogenesis creation_date: 2016-11-09T12:20:01Z [Term] id: GO:1905690 name: nucleus disassembly namespace: biological_process def: "The disaggregation of a nucleus into its constituent components." [GO_REF:0000079, GOC:autophagy, GOC:pr, GOC:TermGenie] synonym: "cell nucleus disassembly" EXACT [GOC:TermGenie] is_a: GO:0006997 ! nucleus organization is_a: GO:1903008 ! organelle disassembly intersection_of: GO:0022411 ! cellular component disassembly intersection_of: RO:0002590 GO:0005634 ! results in disassembly of nucleus relationship: RO:0002590 GO:0005634 ! results in disassembly of nucleus creation_date: 2016-11-14T13:38:57Z [Term] id: GO:1905720 name: cytoplasmic microtubule bundle namespace: cellular_component def: "Any microtubule bundle that is part of a cytoplasm." [GO_REF:0000064, GOC:TermGenie, PMID:11007487, PMID:26124291] synonym: "microtubule bundle of cytoplasm" EXACT [GOC:TermGenie] synonym: "microtubule fascicle of cytoplasm" EXACT [GOC:TermGenie] is_a: GO:0097427 ! microtubule bundle intersection_of: GO:0097427 ! microtubule bundle intersection_of: BFO:0000050 GO:0005737 ! part of cytoplasm relationship: BFO:0000050 GO:0005737 ! part of cytoplasm creation_date: 2016-11-24T16:52:02Z [Term] id: GO:1905755 name: protein localization to cytoplasmic microtubule namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within a cytoplasmic microtubule." [GO_REF:0000087, GOC:TermGenie, PMID:15177031] synonym: "protein localisation to cytoplasmic microtubule" EXACT [GOC:TermGenie] is_a: GO:0035372 ! protein localization to microtubule intersection_of: GO:0008104 ! protein localization intersection_of: RO:0002339 GO:0005881 ! has target end location cytoplasmic microtubule relationship: RO:0002339 GO:0005881 ! has target end location cytoplasmic microtubule creation_date: 2016-12-12T15:31:07Z [Term] id: GO:1905770 name: regulation of mesodermal cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mesodermal cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23765923] synonym: "regulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048333 ! regulates (processual) mesodermal cell differentiation relationship: RO:0002211 GO:0048333 ! regulates (processual) mesodermal cell differentiation creation_date: 2016-12-21T12:44:13Z [Term] id: GO:1905771 name: negative regulation of mesodermal cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesodermal cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23765923] synonym: "down regulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of mesodermal cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of mesodermal cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of mesodermal cell differentiation" EXACT [GOC:TermGenie] synonym: "negative regulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:1905770 ! regulation of mesodermal cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048333 ! negatively regulates mesodermal cell differentiation relationship: RO:0002212 GO:0048333 ! negatively regulates mesodermal cell differentiation creation_date: 2016-12-21T12:44:23Z [Term] id: GO:1905772 name: positive regulation of mesodermal cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mesodermal cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23765923] synonym: "positive regulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of mesodermal cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of mesodermal cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of mesodermal cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:1905770 ! regulation of mesodermal cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0048333 ! positively regulates mesodermal cell differentiation relationship: RO:0002213 GO:0048333 ! positively regulates mesodermal cell differentiation creation_date: 2016-12-21T12:44:32Z [Term] id: GO:1905806 name: regulation of synapse pruning namespace: biological_process def: "Any process that modulates the frequency, rate or extent of synapse pruning." [GO_REF:0000058, GOC:TermGenie, PMID:27779093] synonym: "regulation of synapse clearance" EXACT [] synonym: "regulation of synapse elimination" EXACT [] synonym: "regulation of synapse removal" EXACT [] is_a: GO:0050807 ! regulation of synapse organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0098883 ! regulates (processual) synapse pruning relationship: RO:0002211 GO:0098883 ! regulates (processual) synapse pruning creation_date: 2017-01-11T22:03:15Z [Term] id: GO:1905807 name: negative regulation of synapse pruning namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of synapse pruning." [GO_REF:0000058, GOC:TermGenie, PMID:27779093] synonym: "down regulation of synapse disassembly" EXACT [GOC:TermGenie] synonym: "down-regulation of synapse disassembly" EXACT [GOC:TermGenie] synonym: "downregulation of synapse disassembly" EXACT [GOC:TermGenie] is_a: GO:1905806 ! regulation of synapse pruning is_a: GO:1905809 ! negative regulation of synapse organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0098883 ! negatively regulates synapse pruning relationship: RO:0002212 GO:0098883 ! negatively regulates synapse pruning creation_date: 2017-01-11T22:03:24Z [Term] id: GO:1905808 name: positive regulation of synapse pruning namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of synapse pruning." [GO_REF:0000058, GOC:TermGenie, PMID:27779093] synonym: "up regulation of synapse disassembly" EXACT [GOC:TermGenie] synonym: "up-regulation of synapse disassembly" EXACT [GOC:TermGenie] synonym: "upregulation of synapse disassembly" EXACT [GOC:TermGenie] is_a: GO:0051130 ! positive regulation of cellular component organization is_a: GO:1905806 ! regulation of synapse pruning intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0098883 ! positively regulates synapse pruning relationship: RO:0002213 GO:0098883 ! positively regulates synapse pruning creation_date: 2017-01-11T22:03:33Z [Term] id: GO:1905809 name: negative regulation of synapse organization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of synapse organization." [GO_REF:0000058, GOC:TermGenie, PMID:27779093] synonym: "down regulation of synapse development" EXACT [GOC:TermGenie] synonym: "down regulation of synapse organisation" EXACT [GOC:TermGenie] synonym: "down regulation of synapse organization" EXACT [GOC:TermGenie] synonym: "down-regulation of synapse development" EXACT [GOC:TermGenie] synonym: "down-regulation of synapse organisation" EXACT [GOC:TermGenie] synonym: "down-regulation of synapse organization" EXACT [GOC:TermGenie] synonym: "downregulation of synapse development" EXACT [GOC:TermGenie] synonym: "downregulation of synapse organisation" EXACT [GOC:TermGenie] synonym: "downregulation of synapse organization" EXACT [GOC:TermGenie] synonym: "negative regulation of synapse development" EXACT [GOC:TermGenie] synonym: "negative regulation of synapse organisation" EXACT [GOC:TermGenie] is_a: GO:0050807 ! regulation of synapse organization is_a: GO:0051129 ! negative regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0050808 ! negatively regulates synapse organization relationship: RO:0002212 GO:0050808 ! negatively regulates synapse organization creation_date: 2017-01-11T22:03:41Z [Term] id: GO:1905821 name: positive regulation of chromosome condensation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of chromosome condensation." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:17268547] synonym: "positive regulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie] synonym: "positive regulation of nuclear chromosome condensation" EXACT [GOC:TermGenie] synonym: "up regulation of chromosome condensation" EXACT [GOC:TermGenie] synonym: "up regulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie] synonym: "up regulation of nuclear chromosome condensation" EXACT [GOC:TermGenie] synonym: "up-regulation of chromosome condensation" EXACT [GOC:TermGenie] synonym: "up-regulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie] synonym: "up-regulation of nuclear chromosome condensation" EXACT [GOC:TermGenie] synonym: "upregulation of chromosome condensation" EXACT [GOC:TermGenie] synonym: "upregulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie] synonym: "upregulation of nuclear chromosome condensation" EXACT [GOC:TermGenie] is_a: GO:0060623 ! regulation of chromosome condensation is_a: GO:2001252 ! positive regulation of chromosome organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030261 ! positively regulates chromosome condensation relationship: RO:0002213 GO:0030261 ! positively regulates chromosome condensation creation_date: 2017-01-13T14:13:44Z [Term] id: GO:1905833 name: negative regulation of microtubule nucleation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of microtubule nucleation." [GO_REF:0000058, GOC:TermGenie, PMID:27689799] synonym: "down regulation of microtubule nucleation" EXACT [GOC:TermGenie] synonym: "down-regulation of microtubule nucleation" EXACT [GOC:TermGenie] synonym: "downregulation of microtubule nucleation" EXACT [GOC:TermGenie] is_a: GO:0010968 ! regulation of microtubule nucleation is_a: GO:0031115 ! negative regulation of microtubule polymerization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007020 ! negatively regulates microtubule nucleation relationship: RO:0002212 GO:0007020 ! negatively regulates microtubule nucleation creation_date: 2017-01-17T12:00:56Z [Term] id: GO:1905867 name: epididymis development namespace: biological_process def: "The process whose specific outcome is the progression of an epididymis over time, from its formation to the mature structure." [GO_REF:0000094, GOC:TermGenie, PMID:12388089] synonym: "epididymus development" EXACT [GOC:TermGenie] is_a: GO:0035295 ! tube development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001301 ! results in development of epididymis relationship: RO:0002296 UBERON:0001301 ! results in development of epididymis creation_date: 2017-01-27T00:00:33Z [Term] id: GO:1905871 name: regulation of protein localization to cell leading edge namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein localization to cell leading edge." [GO_REF:0000058, GOC:TermGenie, PMID:26324884] synonym: "regulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] synonym: "regulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] synonym: "regulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] is_a: GO:0032880 ! regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1902463 ! regulates (processual) protein localization to cell leading edge relationship: RO:0002211 GO:1902463 ! regulates (processual) protein localization to cell leading edge creation_date: 2017-01-27T19:34:55Z [Term] id: GO:1905872 name: negative regulation of protein localization to cell leading edge namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell leading edge." [GO_REF:0000058, GOC:TermGenie, PMID:26324884] synonym: "down regulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] synonym: "down regulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization to cell leading edge" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to cell leading edge" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to cell leading edge" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] is_a: GO:1903828 ! negative regulation of protein localization is_a: GO:1905871 ! regulation of protein localization to cell leading edge intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1902463 ! negatively regulates protein localization to cell leading edge relationship: RO:0002212 GO:1902463 ! negatively regulates protein localization to cell leading edge creation_date: 2017-01-27T19:35:04Z [Term] id: GO:1905873 name: positive regulation of protein localization to cell leading edge namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein localization to cell leading edge." [GO_REF:0000058, GOC:TermGenie, PMID:26324884] synonym: "positive regulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization to cell leading edge" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to cell leading edge" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to cell leading edge" EXACT [GOC:TermGenie] is_a: GO:1903829 ! positive regulation of protein localization is_a: GO:1905871 ! regulation of protein localization to cell leading edge intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1902463 ! positively regulates protein localization to cell leading edge relationship: RO:0002213 GO:1902463 ! positively regulates protein localization to cell leading edge creation_date: 2017-01-27T19:35:13Z [Term] id: GO:1905879 name: regulation of oogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of oogenesis." [GO_REF:0000058, GOC:TermGenie, PMID:26434723] synonym: "regulation of ovum development" EXACT [GOC:TermGenie] is_a: GO:0051239 ! regulation of multicellular organismal process is_a: GO:0060284 ! regulation of cell development is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048477 ! regulates (processual) oogenesis relationship: RO:0002211 GO:0048477 ! regulates (processual) oogenesis creation_date: 2017-01-31T09:31:05Z [Term] id: GO:1905880 name: negative regulation of oogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of oogenesis." [GO_REF:0000058, GOC:TermGenie, PMID:26434723] synonym: "down regulation of oogenesis" EXACT [GOC:TermGenie] synonym: "down regulation of ovum development" EXACT [GOC:TermGenie] synonym: "down-regulation of oogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of ovum development" EXACT [GOC:TermGenie] synonym: "downregulation of oogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of ovum development" EXACT [GOC:TermGenie] synonym: "negative regulation of ovum development" EXACT [GOC:TermGenie] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1905879 ! regulation of oogenesis is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048477 ! negatively regulates oogenesis relationship: RO:0002212 GO:0048477 ! negatively regulates oogenesis creation_date: 2017-01-31T09:31:15Z [Term] id: GO:1905881 name: positive regulation of oogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of oogenesis." [GO_REF:0000058, GOC:TermGenie, PMID:26434723] synonym: "positive regulation of ovum development" EXACT [GOC:TermGenie] synonym: "up regulation of oogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of ovum development" EXACT [GOC:TermGenie] synonym: "up-regulation of oogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of ovum development" EXACT [GOC:TermGenie] synonym: "upregulation of oogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of ovum development" EXACT [GOC:TermGenie] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1905879 ! regulation of oogenesis is_a: GO:2000243 ! positive regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0048477 ! positively regulates oogenesis relationship: RO:0002213 GO:0048477 ! positively regulates oogenesis creation_date: 2017-01-31T09:31:23Z [Term] id: GO:1905899 name: regulation of smooth muscle tissue development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of smooth muscle tissue development." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:14709716] is_a: GO:1901861 ! regulation of muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048745 ! regulates (processual) smooth muscle tissue development relationship: RO:0002211 GO:0048745 ! regulates (processual) smooth muscle tissue development creation_date: 2017-02-01T14:31:16Z [Term] id: GO:1905900 name: negative regulation of smooth muscle tissue development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle tissue development." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:14709716] synonym: "down regulation of smooth muscle tissue development" EXACT [GOC:TermGenie] synonym: "down-regulation of smooth muscle tissue development" EXACT [GOC:TermGenie] synonym: "downregulation of smooth muscle tissue development" EXACT [GOC:TermGenie] is_a: GO:1901862 ! negative regulation of muscle tissue development is_a: GO:1905899 ! regulation of smooth muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048745 ! negatively regulates smooth muscle tissue development relationship: RO:0002212 GO:0048745 ! negatively regulates smooth muscle tissue development creation_date: 2017-02-01T14:31:24Z [Term] id: GO:1905901 name: positive regulation of smooth muscle tissue development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of smooth muscle tissue development." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:14709716] synonym: "up regulation of smooth muscle tissue development" EXACT [GOC:TermGenie] synonym: "up-regulation of smooth muscle tissue development" EXACT [GOC:TermGenie] synonym: "upregulation of smooth muscle tissue development" EXACT [GOC:TermGenie] is_a: GO:1901863 ! positive regulation of muscle tissue development is_a: GO:1905899 ! regulation of smooth muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0048745 ! positively regulates smooth muscle tissue development relationship: RO:0002213 GO:0048745 ! positively regulates smooth muscle tissue development creation_date: 2017-02-01T14:31:33Z [Term] id: GO:1905902 name: regulation of mesoderm formation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mesoderm formation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23939491] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001707 ! regulates (processual) mesoderm formation relationship: RO:0002211 GO:0001707 ! regulates (processual) mesoderm formation creation_date: 2017-02-03T12:28:20Z [Term] id: GO:1905903 name: negative regulation of mesoderm formation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm formation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23939491] synonym: "down regulation of mesoderm formation" EXACT [GOC:TermGenie] synonym: "down-regulation of mesoderm formation" EXACT [GOC:TermGenie] synonym: "downregulation of mesoderm formation" EXACT [GOC:TermGenie] is_a: GO:1905902 ! regulation of mesoderm formation is_a: GO:2000381 ! negative regulation of mesoderm development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001707 ! negatively regulates mesoderm formation relationship: RO:0002212 GO:0001707 ! negatively regulates mesoderm formation creation_date: 2017-02-03T12:28:29Z [Term] id: GO:1905904 name: positive regulation of mesoderm formation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mesoderm formation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23939491] synonym: "up regulation of mesoderm formation" EXACT [GOC:TermGenie] synonym: "up-regulation of mesoderm formation" EXACT [GOC:TermGenie] synonym: "upregulation of mesoderm formation" EXACT [GOC:TermGenie] is_a: GO:1905902 ! regulation of mesoderm formation is_a: GO:2000382 ! positive regulation of mesoderm development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001707 ! positively regulates mesoderm formation relationship: RO:0002213 GO:0001707 ! positively regulates mesoderm formation creation_date: 2017-02-03T12:28:38Z [Term] id: GO:1905921 name: regulation of acetylcholine biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of acetylcholine biosynthetic process." [GO_REF:0000058, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:20164328] synonym: "regulation of acetylcholine anabolism" EXACT [GOC:TermGenie] synonym: "regulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] synonym: "regulation of acetylcholine formation" EXACT [GOC:TermGenie] synonym: "regulation of acetylcholine synthesis" EXACT [GOC:TermGenie] is_a: GO:0009889 ! regulation of biosynthetic process is_a: GO:0060408 ! regulation of acetylcholine metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0008292 ! regulates (processual) acetylcholine biosynthetic process relationship: RO:0002211 GO:0008292 ! regulates (processual) acetylcholine biosynthetic process creation_date: 2017-02-08T13:08:30Z [Term] id: GO:1905922 name: negative regulation of acetylcholine biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of acetylcholine biosynthetic process." [GO_REF:0000058, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:20164328] synonym: "down regulation of acetylcholine anabolism" EXACT [GOC:TermGenie] synonym: "down regulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] synonym: "down regulation of acetylcholine biosynthetic process" EXACT [GOC:TermGenie] synonym: "down regulation of acetylcholine formation" EXACT [GOC:TermGenie] synonym: "down regulation of acetylcholine synthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of acetylcholine anabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of acetylcholine biosynthetic process" EXACT [GOC:TermGenie] synonym: "down-regulation of acetylcholine formation" EXACT [GOC:TermGenie] synonym: "down-regulation of acetylcholine synthesis" EXACT [GOC:TermGenie] synonym: "downregulation of acetylcholine anabolism" EXACT [GOC:TermGenie] synonym: "downregulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] synonym: "downregulation of acetylcholine biosynthetic process" EXACT [GOC:TermGenie] synonym: "downregulation of acetylcholine formation" EXACT [GOC:TermGenie] synonym: "downregulation of acetylcholine synthesis" EXACT [GOC:TermGenie] synonym: "negative regulation of acetylcholine anabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] synonym: "negative regulation of acetylcholine formation" EXACT [GOC:TermGenie] synonym: "negative regulation of acetylcholine synthesis" EXACT [GOC:TermGenie] is_a: GO:0009890 ! negative regulation of biosynthetic process is_a: GO:0060410 ! negative regulation of acetylcholine metabolic process is_a: GO:1905921 ! regulation of acetylcholine biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0008292 ! negatively regulates acetylcholine biosynthetic process relationship: RO:0002212 GO:0008292 ! negatively regulates acetylcholine biosynthetic process creation_date: 2017-02-08T13:08:39Z [Term] id: GO:1905923 name: positive regulation of acetylcholine biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of acetylcholine biosynthetic process." [GO_REF:0000058, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:20164328] synonym: "positive regulation of acetylcholine anabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] synonym: "positive regulation of acetylcholine formation" EXACT [GOC:TermGenie] synonym: "positive regulation of acetylcholine synthesis" EXACT [GOC:TermGenie] synonym: "up regulation of acetylcholine anabolism" EXACT [GOC:TermGenie] synonym: "up regulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] synonym: "up regulation of acetylcholine biosynthetic process" EXACT [GOC:TermGenie] synonym: "up regulation of acetylcholine formation" EXACT [GOC:TermGenie] synonym: "up regulation of acetylcholine synthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of acetylcholine anabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of acetylcholine biosynthetic process" EXACT [GOC:TermGenie] synonym: "up-regulation of acetylcholine formation" EXACT [GOC:TermGenie] synonym: "up-regulation of acetylcholine synthesis" EXACT [GOC:TermGenie] synonym: "upregulation of acetylcholine anabolism" EXACT [GOC:TermGenie] synonym: "upregulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] synonym: "upregulation of acetylcholine biosynthetic process" EXACT [GOC:TermGenie] synonym: "upregulation of acetylcholine formation" EXACT [GOC:TermGenie] synonym: "upregulation of acetylcholine synthesis" EXACT [GOC:TermGenie] is_a: GO:0009891 ! positive regulation of biosynthetic process is_a: GO:0060409 ! positive regulation of acetylcholine metabolic process is_a: GO:1905921 ! regulation of acetylcholine biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0008292 ! positively regulates acetylcholine biosynthetic process relationship: RO:0002213 GO:0008292 ! positively regulates acetylcholine biosynthetic process creation_date: 2017-02-08T13:08:48Z [Term] id: GO:1905936 name: regulation of germ cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of germ cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:15342467] is_a: GO:0042127 ! regulation of cell population proliferation is_a: GO:0051239 ! regulation of multicellular organismal process is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0036093 ! regulates (processual) germ cell proliferation relationship: RO:0002211 GO:0036093 ! regulates (processual) germ cell proliferation creation_date: 2017-02-09T14:51:31Z [Term] id: GO:1905937 name: negative regulation of germ cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of germ cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:15342467] synonym: "down regulation of germ cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of germ cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of germ cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1905936 ! regulation of germ cell proliferation is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0036093 ! negatively regulates germ cell proliferation relationship: RO:0002212 GO:0036093 ! negatively regulates germ cell proliferation creation_date: 2017-02-09T14:51:41Z [Term] id: GO:1905938 name: positive regulation of germ cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of germ cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:15342467] synonym: "up regulation of germ cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of germ cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of germ cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1905936 ! regulation of germ cell proliferation is_a: GO:2000243 ! positive regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0036093 ! positively regulates germ cell proliferation relationship: RO:0002213 GO:0036093 ! positively regulates germ cell proliferation creation_date: 2017-02-09T14:51:51Z [Term] id: GO:1905939 name: regulation of gonad development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of gonad development." [GO_REF:0000058, GOC:TermGenie, PMID:15342467] synonym: "regulation of gonadogenesis" EXACT [GOC:TermGenie] is_a: GO:0050793 ! regulation of developmental process is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0008406 ! regulates (processual) gonad development relationship: RO:0002211 GO:0008406 ! regulates (processual) gonad development creation_date: 2017-02-09T17:01:50Z [Term] id: GO:1905940 name: negative regulation of gonad development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of gonad development." [GO_REF:0000058, GOC:TermGenie, PMID:15342467] synonym: "down regulation of gonad development" EXACT [GOC:TermGenie] synonym: "down regulation of gonadogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of gonad development" EXACT [GOC:TermGenie] synonym: "down-regulation of gonadogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of gonad development" EXACT [GOC:TermGenie] synonym: "downregulation of gonadogenesis" EXACT [GOC:TermGenie] synonym: "negative regulation of gonadogenesis" EXACT [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1905939 ! regulation of gonad development is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0008406 ! negatively regulates gonad development relationship: RO:0002212 GO:0008406 ! negatively regulates gonad development creation_date: 2017-02-09T17:01:59Z [Term] id: GO:1905941 name: positive regulation of gonad development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of gonad development." [GO_REF:0000058, GOC:TermGenie, PMID:15342467] synonym: "positive regulation of gonadogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of gonad development" EXACT [GOC:TermGenie] synonym: "up regulation of gonadogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of gonad development" EXACT [GOC:TermGenie] synonym: "up-regulation of gonadogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of gonad development" EXACT [GOC:TermGenie] synonym: "upregulation of gonadogenesis" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1905939 ! regulation of gonad development is_a: GO:2000243 ! positive regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0008406 ! positively regulates gonad development relationship: RO:0002213 GO:0008406 ! positively regulates gonad development creation_date: 2017-02-09T17:02:08Z [Term] id: GO:1905952 name: regulation of lipid localization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of lipid localization." [GO_REF:0000058, GOC:TermGenie, PMID:17564681] synonym: "regulation of lipid localisation" EXACT [GOC:TermGenie] is_a: GO:0032879 ! regulation of localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0010876 ! regulates (processual) lipid localization relationship: RO:0002211 GO:0010876 ! regulates (processual) lipid localization creation_date: 2017-02-21T12:12:22Z [Term] id: GO:1905953 name: negative regulation of lipid localization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of lipid localization." [GO_REF:0000058, GOC:TermGenie, PMID:17564681] synonym: "down regulation of lipid localisation" EXACT [GOC:TermGenie] synonym: "down regulation of lipid localization" EXACT [GOC:TermGenie] synonym: "down-regulation of lipid localisation" EXACT [GOC:TermGenie] synonym: "down-regulation of lipid localization" EXACT [GOC:TermGenie] synonym: "downregulation of lipid localisation" EXACT [GOC:TermGenie] synonym: "downregulation of lipid localization" EXACT [GOC:TermGenie] synonym: "negative regulation of lipid localisation" EXACT [GOC:TermGenie] is_a: GO:0048519 ! negative regulation of biological process is_a: GO:1905952 ! regulation of lipid localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0010876 ! negatively regulates lipid localization relationship: RO:0002212 GO:0010876 ! negatively regulates lipid localization creation_date: 2017-02-21T12:12:41Z [Term] id: GO:1905954 name: positive regulation of lipid localization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of lipid localization." [GO_REF:0000058, GOC:TermGenie, PMID:17564681] synonym: "positive regulation of lipid localisation" EXACT [GOC:TermGenie] synonym: "up regulation of lipid localisation" EXACT [GOC:TermGenie] synonym: "up regulation of lipid localization" EXACT [GOC:TermGenie] synonym: "up-regulation of lipid localisation" EXACT [GOC:TermGenie] synonym: "up-regulation of lipid localization" EXACT [GOC:TermGenie] synonym: "upregulation of lipid localisation" EXACT [GOC:TermGenie] synonym: "upregulation of lipid localization" EXACT [GOC:TermGenie] is_a: GO:0048518 ! positive regulation of biological process is_a: GO:1905952 ! regulation of lipid localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0010876 ! positively regulates lipid localization relationship: RO:0002213 GO:0010876 ! positively regulates lipid localization creation_date: 2017-02-21T12:12:49Z [Term] id: GO:1905955 name: negative regulation of endothelial tube morphogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of endothelial tube morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:25961718] synonym: "down regulation of endothelial tube morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of endothelial tube morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of endothelial tube morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1901509 ! regulation of endothelial tube morphogenesis is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0061154 ! negatively regulates endothelial tube morphogenesis relationship: RO:0002212 GO:0061154 ! negatively regulates endothelial tube morphogenesis creation_date: 2017-02-21T15:17:31Z [Term] id: GO:1905956 name: positive regulation of endothelial tube morphogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of endothelial tube morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:25961718] synonym: "up regulation of endothelial tube morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of endothelial tube morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of endothelial tube morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1901509 ! regulation of endothelial tube morphogenesis is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0061154 ! positively regulates endothelial tube morphogenesis relationship: RO:0002213 GO:0061154 ! positively regulates endothelial tube morphogenesis creation_date: 2017-02-21T15:17:39Z [Term] id: GO:1990009 name: retinal cell apoptotic process namespace: biological_process def: "Any apoptotic process in a retinal cell." [GOC:mtg_apoptosis, PMID:15558487, PMID:24664675] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0009004 ! occurs in retinal cell relationship: BFO:0000066 CL:0009004 ! occurs in retinal cell creation_date: 2012-12-12T10:15:08Z [Term] id: GO:1990010 name: compound eye retinal cell apoptotic process namespace: biological_process def: "Any apoptotic process in a compound eye retinal cell." [GOC:mtg_apoptosis, PMID:12021768] is_a: GO:1990009 ! retinal cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0009001 ! occurs in compound eye retinal cell relationship: BFO:0000066 CL:0009001 ! occurs in compound eye retinal cell creation_date: 2012-12-12T10:21:07Z [Term] id: GO:1990182 name: exosomal secretion namespace: biological_process def: "The process whereby a membrane-bounded vesicle is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane." [GOC:hjd, PMID:10572093, PMID:12154376, PMID:16773132, PMID:18617898] synonym: "exosomal secretory pathway" EXACT [PMID:18617898] synonym: "extracellular vesicular exosome secretion" EXACT [GOC:hjd] synonym: "multi-vesicular body fusion with plasma membrane" EXACT [] synonym: "secretion of exosome" EXACT [PMID:18617898] is_a: GO:0006887 ! exocytosis is_a: GO:0051650 ! establishment of vesicle localization intersection_of: GO:0006887 ! exocytosis intersection_of: RO:0004009 GO:0070062 ! has primary input extracellular exosome relationship: BFO:0000050 GO:0097734 ! part of extracellular exosome biogenesis relationship: RO:0004009 GO:0070062 ! has primary input extracellular exosome creation_date: 2013-09-04T21:08:14Z [Term] id: GO:1990234 name: transferase complex namespace: cellular_component def: "A protein complex capable of catalyzing the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor)." [GOC:bhm, PMID:16540464] is_a: GO:1902494 ! catalytic complex intersection_of: GO:1902494 ! catalytic complex intersection_of: RO:0002215 GO:0016740 ! capable of transferase activity relationship: RO:0002215 GO:0016740 ! capable of transferase activity creation_date: 2013-11-12T13:20:12Z [Term] id: GO:1990280 name: RNA localization to chromatin namespace: biological_process def: "A process in which RNA is transported to and maintained in a part of a chromosome that is organized into chromatin." [GOC:dos, GOC:mah, PMID:22582262] synonym: "RNA localisation to chromatin" EXACT [] is_a: GO:0006403 ! RNA localization intersection_of: GO:0006403 ! RNA localization intersection_of: RO:0002339 GO:0000785 ! has target end location chromatin relationship: RO:0002339 GO:0000785 ! has target end location chromatin creation_date: 2014-01-30T15:55:34Z [Term] id: GO:1990351 name: transporter complex namespace: cellular_component def: "A protein complex facilitating transport of molecules (proteins, small molecules, nucleic acids) into, out of or within a cell, or between cells." [GOC:bhm, PMID:15449578] is_a: GO:0032991 ! protein-containing complex intersection_of: GO:0032991 ! protein-containing complex intersection_of: RO:0002215 GO:0005215 ! capable of transporter activity relationship: RO:0002215 GO:0005215 ! capable of transporter activity creation_date: 2014-03-26T14:23:27Z [Term] id: GO:1990375 name: baculum development namespace: biological_process def: "The reproductive developmental process whose specific outcome is the progression of the baculum over time, from its formation to the mature structure." [GOC:sl, PMID:21471296] synonym: "os penis development" EXACT [GOC:sl] synonym: "penile bone development" EXACT [GOC:sl] synonym: "penis bone development" EXACT [GOC:sl] is_a: GO:0048608 ! reproductive structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0006435 ! results in development of os penis relationship: RO:0002296 UBERON:0006435 ! results in development of os penis creation_date: 2014-05-01T23:59:13Z [Term] id: GO:1990502 name: dense core granule maturation namespace: biological_process def: "Steps required to transform a dense core granule generated at the trans-Golgi network into a fully formed and transmissible dense core granule. Dense core granule maturation proceeds through clathrin-mediated membrane remodeling events and is essential for efficient processing of cargo within dense core granules as well as for removing factors that might otherwise interfere with dense core granule trafficking and exocytosis." [GOC:kmv, PMID:22654674] synonym: "dense core vesicle maturation" EXACT [] is_a: GO:0061792 ! secretory granule maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 GO:0031045 ! results in maturation of dense core granule relationship: RO:0002299 GO:0031045 ! results in maturation of dense core granule creation_date: 2014-09-30T20:35:11Z [Term] id: GO:1990705 name: cholangiocyte proliferation namespace: biological_process def: "The multiplication or reproduction of cholangiocytes, resulting in the expansion of the cholangiocyte population. A cholangiocyte is an epithelial cell that is part of the bile duct. Cholangiocytes contribute to bile secretion via net release of bicarbonate and water." [PMID:24434010] synonym: "hepatoblast proliferation" EXACT [] is_a: GO:0050673 ! epithelial cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:1000488 ! acts on population of cholangiocyte relationship: RO:0012003 CL:1000488 ! acts on population of cholangiocyte creation_date: 2015-03-16T23:23:50Z [Term] id: GO:1990748 name: cellular detoxification namespace: biological_process def: "Any process carried out at the cellular level that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance." [GOC:vw] is_a: GO:0009987 ! cellular process is_a: GO:0098754 ! detoxification intersection_of: GO:0098754 ! detoxification intersection_of: BFO:0000066 CL:0000000 ! occurs in cell relationship: BFO:0000050 GO:0097237 ! part of cellular response to toxic substance relationship: BFO:0000066 CL:0000000 ! occurs in cell creation_date: 2015-05-18T16:17:46Z [Term] id: GO:1990765 name: colon smooth muscle contraction namespace: biological_process def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry of the large intestine, exclusive of the rectum. The colon is that part of the large intestine that connects the small intestine to the rectum." [PMID:24170253] is_a: GO:0006939 ! smooth muscle contraction intersection_of: GO:0006939 ! smooth muscle contraction intersection_of: BFO:0000066 UBERON:0001155 ! occurs in colon relationship: BFO:0000050 GO:0014827 ! part of intestine smooth muscle contraction relationship: BFO:0000066 UBERON:0001155 ! occurs in colon relationship: RO:0002160 NCBITaxon:7742 ! only in taxon Vertebrata relationship: RO:0002162 NCBITaxon:7742 {all_only="true"} ! in taxon Vertebrata creation_date: 2015-06-10T18:29:21Z [Term] id: GO:1990768 name: gastric mucosal blood circulation namespace: biological_process def: "The flow of blood through the gastric mucosa of an animal, enabling the transport of nutrients and the removal of waste products." [PMID:10807413] synonym: "stomach mucosal blood circulation" EXACT [] is_a: GO:0008015 ! blood circulation intersection_of: GO:0008015 ! blood circulation intersection_of: BFO:0000066 UBERON:0004786 ! occurs in gastrointestinal system mucosa relationship: BFO:0000066 UBERON:0004786 ! occurs in gastrointestinal system mucosa creation_date: 2015-06-10T20:11:09Z [Term] id: GO:1990770 name: small intestine smooth muscle contraction namespace: biological_process def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry in the intestine between the stomach and the large intestine." [PMID:11991626] is_a: GO:0006939 ! smooth muscle contraction intersection_of: GO:0006939 ! smooth muscle contraction intersection_of: BFO:0000066 UBERON:0002108 ! occurs in small intestine relationship: BFO:0000050 GO:0014827 ! part of intestine smooth muscle contraction relationship: BFO:0000066 UBERON:0002108 ! occurs in small intestine relationship: RO:0002160 NCBITaxon:7742 ! only in taxon Vertebrata relationship: RO:0002162 NCBITaxon:7742 {all_only="true"} ! in taxon Vertebrata creation_date: 2015-06-11T18:02:33Z [Term] id: GO:1990778 name: protein localization to cell periphery namespace: biological_process def: "A process in which a protein is transported to, or maintained in, the cell periphery." [PMID:18216290] is_a: GO:0008104 ! protein localization intersection_of: GO:0008104 ! protein localization intersection_of: RO:0002339 GO:0071944 ! has target end location cell periphery relationship: RO:0002339 GO:0071944 ! has target end location cell periphery creation_date: 2015-06-18T22:37:39Z [Term] id: GO:1990849 name: vacuolar localization namespace: biological_process def: "Any process in which the vacuole is transported to, and/or maintained in, a specific location within the cell." [PMID:26283797] synonym: "maintenance of vacuolar localization" EXACT [] synonym: "maintenance of vacuole localization" EXACT [] synonym: "maintenance of vacuole location" EXACT [] is_a: GO:0051640 ! organelle localization intersection_of: GO:0051179 ! localization intersection_of: RO:0004009 GO:0005773 ! has primary input vacuole relationship: RO:0004009 GO:0005773 ! has primary input vacuole creation_date: 2015-09-10T08:16:02Z [Term] id: GO:1990863 name: acinar cell proliferation namespace: biological_process def: "The multiplication or reproduction of acinar cells, resulting in the expansion of a cell population. An acinar cell is a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini (singular acinus)." [PMID:9788538] synonym: "acinic cell proliferation" EXACT [] synonym: "acinous cell proliferation" EXACT [] is_a: GO:0050673 ! epithelial cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000622 ! acts on population of acinar cell relationship: RO:0012003 CL:0000622 ! acts on population of acinar cell creation_date: 2015-09-25T14:26:09Z [Term] id: GO:1990874 name: vascular associated smooth muscle cell proliferation namespace: biological_process def: "The multiplication or reproduction of vascular smooth muscle cells, resulting in the expansion of a cell population. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels." [PMID:23246467] synonym: "vascular smooth muscle cell proliferation" EXACT [] synonym: "VSMC proliferation" EXACT [] is_a: GO:0048659 ! smooth muscle cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000359 ! acts on population of vascular associated smooth muscle cell relationship: RO:0012003 CL:0000359 ! acts on population of vascular associated smooth muscle cell creation_date: 2015-09-29T16:34:59Z [Term] id: GO:1990904 name: ribonucleoprotein complex namespace: cellular_component def: "A macromolecular complex that contains both RNA and protein molecules." [GOC:krc, GOC:vesicles] synonym: "protein-RNA complex" EXACT [] synonym: "RNA-protein complex" EXACT [] synonym: "RNP" EXACT [] xref: Wikipedia:Ribonucleoprotein is_a: GO:0032991 ! protein-containing complex relationship: BFO:0000051 CHEBI:33697 ! has part ribonucleic acid creation_date: 2015-11-19T12:26:37Z [Term] id: GO:1990917 name: ooplasm namespace: cellular_component def: "The cytoplasm of an ovum." [PMID:19022436] is_a: GO:0005737 ! cytoplasm intersection_of: GO:0005737 ! cytoplasm intersection_of: BFO:0000050 CL:0000025 ! part of egg cell relationship: BFO:0000050 CL:0000025 ! part of egg cell creation_date: 2015-12-10T21:40:16Z [Term] id: GO:2000018 name: regulation of male gonad development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of male gonad development." [GOC:obol, GOC:yaf] synonym: "regulation of testicular development" EXACT [GOC:obol] synonym: "regulation of testis development" EXACT [GOC:obol] is_a: GO:1905939 ! regulation of gonad development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0008584 ! regulates (processual) male gonad development relationship: RO:0002211 GO:0008584 ! regulates (processual) male gonad development creation_date: 2010-07-15T03:29:05Z [Term] id: GO:2000019 name: negative regulation of male gonad development namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of male gonad development." [GOC:obol, GOC:yaf] synonym: "negative regulation of testicular development" EXACT [GOC:obol] synonym: "negative regulation of testis development" EXACT [GOC:obol] is_a: GO:1905940 ! negative regulation of gonad development is_a: GO:2000018 ! regulation of male gonad development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0008584 ! negatively regulates male gonad development relationship: RO:0002212 GO:0008584 ! negatively regulates male gonad development creation_date: 2010-07-15T03:29:10Z [Term] id: GO:2000020 name: positive regulation of male gonad development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of male gonad development." [GOC:obol] synonym: "positive regulation of testicular development" EXACT [GOC:obol] synonym: "positive regulation of testis development" EXACT [GOC:obol] is_a: GO:1905941 ! positive regulation of gonad development is_a: GO:2000018 ! regulation of male gonad development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0008584 ! positively regulates male gonad development relationship: RO:0002213 GO:0008584 ! positively regulates male gonad development creation_date: 2010-07-15T03:29:13Z [Term] id: GO:2000026 name: regulation of multicellular organismal development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of multicellular organismal development." [GOC:obol] is_a: GO:0050793 ! regulation of developmental process is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007275 ! regulates (processual) multicellular organism development relationship: RO:0002211 GO:0007275 ! regulates (processual) multicellular organism development creation_date: 2010-08-05T11:25:59Z [Term] id: GO:2000027 name: regulation of animal organ morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of animal organ morphogenesis." [GOC:obol] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0009887 ! regulates (processual) animal organ morphogenesis relationship: RO:0002211 GO:0009887 ! regulates (processual) animal organ morphogenesis creation_date: 2010-08-05T11:26:27Z [Term] id: GO:2000035 name: regulation of stem cell division namespace: biological_process def: "Any process that modulates the frequency, rate or extent of stem cell division." [GOC:obol] synonym: "regulation of stem cell renewal" EXACT [GOC:obol] is_a: GO:0051302 ! regulation of cell division intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0017145 ! regulates (processual) stem cell division relationship: RO:0002211 GO:0017145 ! regulates (processual) stem cell division creation_date: 2010-08-05T11:34:53Z [Term] id: GO:2000036 name: regulation of stem cell population maintenance namespace: biological_process def: "Any process that modulates the frequency, rate or extent of stem cell population maintenance." [GOC:obol] is_a: GO:0050793 ! regulation of developmental process is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0019827 ! regulates (processual) stem cell population maintenance relationship: RO:0002211 GO:0019827 ! regulates (processual) stem cell population maintenance creation_date: 2010-08-05T11:35:25Z [Term] id: GO:2000061 name: regulation of ureter smooth muscle cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of ureter smooth muscle cell differentiation." [GOC:mtg_kidney_jan10, GOC:obol, GOC:yaf] is_a: GO:0048634 ! regulation of muscle organ development is_a: GO:0051150 ! regulation of smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0072193 ! regulates (processual) ureter smooth muscle cell differentiation relationship: RO:0002211 GO:0072193 ! regulates (processual) ureter smooth muscle cell differentiation creation_date: 2010-08-20T01:44:16Z [Term] id: GO:2000062 name: negative regulation of ureter smooth muscle cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of ureter smooth muscle cell differentiation." [GOC:mtg_kidney_jan10, GOC:obol, GOC:yaf] is_a: GO:0051151 ! negative regulation of smooth muscle cell differentiation is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:2000061 ! regulation of ureter smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0072193 ! negatively regulates ureter smooth muscle cell differentiation relationship: RO:0002212 GO:0072193 ! negatively regulates ureter smooth muscle cell differentiation creation_date: 2010-08-20T01:44:23Z [Term] id: GO:2000063 name: positive regulation of ureter smooth muscle cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of ureter smooth muscle cell differentiation." [GOC:mtg_kidney_jan10, GOC:obol, GOC:yaf] is_a: GO:0051152 ! positive regulation of smooth muscle cell differentiation is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:2000061 ! regulation of ureter smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0072193 ! positively regulates ureter smooth muscle cell differentiation relationship: RO:0002213 GO:0072193 ! positively regulates ureter smooth muscle cell differentiation creation_date: 2010-08-20T01:44:28Z [Term] id: GO:2000068 name: regulation of defense response to insect namespace: biological_process def: "Any process that modulates the frequency, rate or extent of defense response to insect." [GOC:obol] synonym: "regulation of physiological defense response to insect" EXACT [GOC:obol] is_a: GO:0031347 ! regulation of defense response intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002213 ! regulates (processual) defense response to insect relationship: RO:0002211 GO:0002213 ! regulates (processual) defense response to insect creation_date: 2010-08-23T09:30:00Z [Term] id: GO:2000074 name: regulation of type B pancreatic cell development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of pancreatic B cell development." [GOC:obol, GOC:yaf] synonym: "regulation of pancreatic B cell development" EXACT [GOC:mah] synonym: "regulation of pancreatic beta cell development" EXACT [GOC:obol] is_a: GO:0060284 ! regulation of cell development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003323 ! regulates (processual) type B pancreatic cell development relationship: RO:0002211 GO:0003323 ! regulates (processual) type B pancreatic cell development creation_date: 2010-08-27T11:19:37Z [Term] id: GO:2000077 name: negative regulation of type B pancreatic cell development namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic B cell development." [GOC:obol, GOC:yaf] synonym: "negative regulation of pancreatic B cell development" EXACT [GOC:mah] synonym: "negative regulation of pancreatic beta cell development" EXACT [GOC:obol] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:2000074 ! regulation of type B pancreatic cell development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0003323 ! negatively regulates type B pancreatic cell development relationship: RO:0002212 GO:0003323 ! negatively regulates type B pancreatic cell development creation_date: 2010-08-27T11:21:17Z [Term] id: GO:2000078 name: positive regulation of type B pancreatic cell development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of pancreatic B cell development." [GOC:obol, GOC:yaf] synonym: "positive regulation of pancreatic B cell development" EXACT [GOC:mah] synonym: "positive regulation of pancreatic beta cell development" EXACT [GOC:obol] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0030858 ! positive regulation of epithelial cell differentiation is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:2000074 ! regulation of type B pancreatic cell development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0003323 ! positively regulates type B pancreatic cell development relationship: RO:0002213 GO:0003323 ! positively regulates type B pancreatic cell development creation_date: 2010-08-27T11:21:19Z [Term] id: GO:2000084 name: regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis." [GOC:mtg_kidney_jan10] is_a: GO:2000696 ! regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0061261 ! regulates (processual) mesenchymal to epithelial transition involved in mesonephros morphogenesis relationship: RO:0002211 GO:0061261 ! regulates (processual) mesenchymal to epithelial transition involved in mesonephros morphogenesis creation_date: 2010-09-03T06:06:41Z [Term] id: GO:2000085 name: negative regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis." [GOC:mtg_kidney_jan10] is_a: GO:2000084 ! regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis is_a: GO:2000697 ! negative regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0061261 ! negatively regulates mesenchymal to epithelial transition involved in mesonephros morphogenesis relationship: RO:0002212 GO:0061261 ! negatively regulates mesenchymal to epithelial transition involved in mesonephros morphogenesis creation_date: 2010-09-03T06:08:21Z [Term] id: GO:2000086 name: positive regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis." [GOC:mtg_kidney_jan10] is_a: GO:2000084 ! regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis is_a: GO:2000698 ! positive regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0061261 ! positively regulates mesenchymal to epithelial transition involved in mesonephros morphogenesis relationship: RO:0002213 GO:0061261 ! positively regulates mesenchymal to epithelial transition involved in mesonephros morphogenesis creation_date: 2010-09-03T06:08:24Z [Term] id: GO:2000106 name: regulation of leukocyte apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of leukocyte apoptotic process." [GOC:BHF, GOC:mtg_apoptosis] is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0071887 ! regulates (processual) leukocyte apoptotic process relationship: RO:0002211 GO:0071887 ! regulates (processual) leukocyte apoptotic process creation_date: 2010-09-15T01:42:05Z [Term] id: GO:2000107 name: negative regulation of leukocyte apoptotic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte apoptotic process." [GOC:BHF, GOC:mtg_apoptosis] is_a: GO:0043066 ! negative regulation of apoptotic process is_a: GO:2000106 ! regulation of leukocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0071887 ! negatively regulates leukocyte apoptotic process relationship: RO:0002212 GO:0071887 ! negatively regulates leukocyte apoptotic process creation_date: 2010-09-15T01:42:09Z [Term] id: GO:2000108 name: positive regulation of leukocyte apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of leukocyte apoptotic process." [GOC:BHF, GOC:mtg_apoptosis] is_a: GO:0043065 ! positive regulation of apoptotic process is_a: GO:2000106 ! regulation of leukocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0071887 ! positively regulates leukocyte apoptotic process relationship: RO:0002213 GO:0071887 ! positively regulates leukocyte apoptotic process creation_date: 2010-09-15T01:42:12Z [Term] id: GO:2000114 name: regulation of establishment of cell polarity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of establishment of cell polarity." [GOC:dph] synonym: "regulation of cell polarization" EXACT [GOC:obol] is_a: GO:0032878 ! regulation of establishment or maintenance of cell polarity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030010 ! regulates (processual) establishment of cell polarity relationship: RO:0002211 GO:0030010 ! regulates (processual) establishment of cell polarity creation_date: 2010-09-16T01:22:36Z [Term] id: GO:2000136 name: regulation of cell proliferation involved in heart morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell proliferation involved in heart morphogenesis." [GOC:dph] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0061323 ! regulates (processual) cell proliferation involved in heart morphogenesis relationship: RO:0002211 GO:0061323 ! regulates (processual) cell proliferation involved in heart morphogenesis creation_date: 2010-09-29T12:43:53Z [Term] id: GO:2000137 name: negative regulation of cell proliferation involved in heart morphogenesis namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell proliferation involved in heart morphogenesis." [GOC:dph] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:2000136 ! regulation of cell proliferation involved in heart morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0061323 ! negatively regulates cell proliferation involved in heart morphogenesis relationship: RO:0002212 GO:0061323 ! negatively regulates cell proliferation involved in heart morphogenesis creation_date: 2010-09-29T12:43:55Z [Term] id: GO:2000138 name: positive regulation of cell proliferation involved in heart morphogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell proliferation involved in heart morphogenesis." [GOC:dph] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:2000136 ! regulation of cell proliferation involved in heart morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0061323 ! positively regulates cell proliferation involved in heart morphogenesis relationship: RO:0002213 GO:0061323 ! positively regulates cell proliferation involved in heart morphogenesis creation_date: 2010-09-29T12:43:57Z [Term] id: GO:2000145 name: regulation of cell motility namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell motility." [GOC:mah] synonym: "regulation of cell locomotion" EXACT [GOC:obol] synonym: "regulation of movement of a cell" EXACT [GOC:obol] is_a: GO:0040012 ! regulation of locomotion is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048870 ! regulates (processual) cell motility relationship: RO:0002211 GO:0048870 ! regulates (processual) cell motility creation_date: 2010-10-01T09:41:21Z [Term] id: GO:2000146 name: negative regulation of cell motility namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell motility." [GOC:mah] synonym: "negative regulation of cell locomotion" EXACT [GOC:obol] synonym: "negative regulation of movement of a cell" EXACT [GOC:obol] is_a: GO:0040013 ! negative regulation of locomotion is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:2000145 ! regulation of cell motility intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048870 ! negatively regulates cell motility relationship: RO:0002212 GO:0048870 ! negatively regulates cell motility creation_date: 2010-10-01T09:41:26Z [Term] id: GO:2000147 name: positive regulation of cell motility namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell motility." [GOC:mah] synonym: "positive regulation of cell locomotion" EXACT [GOC:obol] synonym: "positive regulation of movement of a cell" EXACT [GOC:obol] is_a: GO:0040017 ! positive regulation of locomotion is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:2000145 ! regulation of cell motility intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0048870 ! positively regulates cell motility relationship: RO:0002213 GO:0048870 ! positively regulates cell motility creation_date: 2010-10-01T09:41:30Z [Term] id: GO:2000155 name: positive regulation of cilium-dependent cell motility namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cilium-dependent cell motility." [GOC:cilia, GOC:jl] is_a: GO:1902019 ! regulation of cilium-dependent cell motility is_a: GO:2000147 ! positive regulation of cell motility intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060285 ! positively regulates cilium-dependent cell motility relationship: RO:0002213 GO:0060285 ! positively regulates cilium-dependent cell motility creation_date: 2010-10-04T12:41:05Z [Term] id: GO:2000172 name: regulation of branching morphogenesis of a nerve namespace: biological_process def: "Any process that modulates the frequency, rate or extent of branching morphogenesis of a nerve." [GOC:BHF] is_a: GO:0060688 ! regulation of morphogenesis of a branching structure intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048755 ! regulates (processual) branching morphogenesis of a nerve relationship: RO:0002211 GO:0048755 ! regulates (processual) branching morphogenesis of a nerve creation_date: 2010-10-07T12:07:54Z [Term] id: GO:2000173 name: negative regulation of branching morphogenesis of a nerve namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of branching morphogenesis of a nerve." [GOC:BHF] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:2000172 ! regulation of branching morphogenesis of a nerve intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048755 ! negatively regulates branching morphogenesis of a nerve relationship: RO:0002212 GO:0048755 ! negatively regulates branching morphogenesis of a nerve creation_date: 2010-10-07T12:07:56Z [Term] id: GO:2000174 name: regulation of pro-T cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of pro-T cell differentiation." [GOC:BHF] synonym: "regulation of pro-T lymphocyte differentiation" EXACT [GOC:obol] is_a: GO:0045580 ! regulation of T cell differentiation is_a: GO:1905456 ! regulation of lymphoid progenitor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002572 ! regulates (processual) pro-T cell differentiation relationship: RO:0002211 GO:0002572 ! regulates (processual) pro-T cell differentiation creation_date: 2010-10-11T10:24:30Z [Term] id: GO:2000175 name: negative regulation of pro-T cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of pro-T cell differentiation." [GOC:BHF] synonym: "negative regulation of pro-T lymphocyte differentiation" EXACT [GOC:obol] is_a: GO:0045581 ! negative regulation of T cell differentiation is_a: GO:1905457 ! negative regulation of lymphoid progenitor cell differentiation is_a: GO:2000174 ! regulation of pro-T cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002572 ! negatively regulates pro-T cell differentiation relationship: RO:0002212 GO:0002572 ! negatively regulates pro-T cell differentiation creation_date: 2010-10-11T10:24:33Z [Term] id: GO:2000176 name: positive regulation of pro-T cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of pro-T cell differentiation." [GOC:BHF] synonym: "positive regulation of pro-T lymphocyte differentiation" EXACT [GOC:obol] is_a: GO:0045582 ! positive regulation of T cell differentiation is_a: GO:1905458 ! positive regulation of lymphoid progenitor cell differentiation is_a: GO:2000174 ! regulation of pro-T cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002572 ! positively regulates pro-T cell differentiation relationship: RO:0002213 GO:0002572 ! positively regulates pro-T cell differentiation creation_date: 2010-10-11T10:24:35Z [Term] id: GO:2000177 name: regulation of neural precursor cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of neural precursor cell proliferation." [GOC:dph, GOC:yaf] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0061351 ! regulates (processual) neural precursor cell proliferation relationship: RO:0002211 GO:0061351 ! regulates (processual) neural precursor cell proliferation creation_date: 2010-10-13T12:40:41Z [Term] id: GO:2000178 name: negative regulation of neural precursor cell proliferation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of neural precursor cell proliferation." [GOC:dph, GOC:yaf] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:2000177 ! regulation of neural precursor cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0061351 ! negatively regulates neural precursor cell proliferation relationship: RO:0002212 GO:0061351 ! negatively regulates neural precursor cell proliferation creation_date: 2010-10-13T12:40:43Z [Term] id: GO:2000179 name: positive regulation of neural precursor cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of neural precursor cell proliferation." [GOC:dph, GOC:yaf] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:2000177 ! regulation of neural precursor cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0061351 ! positively regulates neural precursor cell proliferation relationship: RO:0002213 GO:0061351 ! positively regulates neural precursor cell proliferation creation_date: 2010-10-13T12:40:45Z [Term] id: GO:2000181 name: negative regulation of blood vessel morphogenesis namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis." [GOC:dph, GOC:yaf] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis is_a: GO:1901343 ! negative regulation of vasculature development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048514 ! negatively regulates blood vessel morphogenesis relationship: RO:0002212 GO:0048514 ! negatively regulates blood vessel morphogenesis creation_date: 2010-10-13T12:46:31Z [Term] id: GO:2000185 name: regulation of phosphate transmembrane transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of phosphate transmembrane transport." [GOC:obol] synonym: "regulation of phosphate membrane transport" EXACT [] is_a: GO:0010966 ! regulation of phosphate transport is_a: GO:1903795 ! regulation of inorganic anion transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0035435 ! regulates (processual) phosphate ion transmembrane transport relationship: RO:0002211 GO:0035435 ! regulates (processual) phosphate ion transmembrane transport creation_date: 2010-10-15T11:33:04Z [Term] id: GO:2000186 name: negative regulation of phosphate transmembrane transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of phosphate transmembrane transport." [GOC:obol] synonym: "negative regulation of phosphate membrane transport" EXACT [] is_a: GO:1903796 ! negative regulation of inorganic anion transmembrane transport is_a: GO:2000185 ! regulation of phosphate transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0035435 ! negatively regulates phosphate ion transmembrane transport relationship: RO:0002212 GO:0035435 ! negatively regulates phosphate ion transmembrane transport creation_date: 2010-10-15T11:33:08Z [Term] id: GO:2000187 name: positive regulation of phosphate transmembrane transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of phosphate transmembrane transport." [GOC:obol] synonym: "positive regulation of phosphate membrane transport" EXACT [] is_a: GO:1903797 ! positive regulation of inorganic anion transmembrane transport is_a: GO:2000185 ! regulation of phosphate transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0035435 ! positively regulates phosphate ion transmembrane transport relationship: RO:0002213 GO:0035435 ! positively regulates phosphate ion transmembrane transport creation_date: 2010-10-15T11:33:10Z [Term] id: GO:2000194 name: regulation of female gonad development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of female gonad development." [GOC:obol] synonym: "regulation of ovarian development" EXACT [GOC:obol] synonym: "regulation of ovary development" EXACT [GOC:obol] is_a: GO:1905939 ! regulation of gonad development is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0008585 ! regulates (processual) female gonad development relationship: RO:0002211 GO:0008585 ! regulates (processual) female gonad development creation_date: 2010-10-19T10:45:34Z [Term] id: GO:2000195 name: negative regulation of female gonad development namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of female gonad development." [GOC:obol] synonym: "negative regulation of ovarian development" EXACT [GOC:obol] synonym: "negative regulation of ovary development" EXACT [GOC:obol] is_a: GO:1905940 ! negative regulation of gonad development is_a: GO:2000194 ! regulation of female gonad development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0008585 ! negatively regulates female gonad development relationship: RO:0002212 GO:0008585 ! negatively regulates female gonad development creation_date: 2010-10-19T10:45:38Z [Term] id: GO:2000196 name: positive regulation of female gonad development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of female gonad development." [GOC:obol] synonym: "positive regulation of ovarian development" EXACT [GOC:obol] synonym: "positive regulation of ovary development" EXACT [GOC:obol] is_a: GO:1905941 ! positive regulation of gonad development is_a: GO:2000194 ! regulation of female gonad development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0008585 ! positively regulates female gonad development relationship: RO:0002213 GO:0008585 ! positively regulates female gonad development creation_date: 2010-10-19T10:45:41Z [Term] id: GO:2000226 name: regulation of pancreatic A cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of pancreatic A cell differentiation." [GOC:mah] synonym: "regulation of pancreatic alpha cell differentiation" EXACT [GOC:obol] is_a: GO:0030856 ! regulation of epithelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003310 ! regulates (processual) pancreatic A cell differentiation relationship: RO:0002211 GO:0003310 ! regulates (processual) pancreatic A cell differentiation creation_date: 2010-11-09T03:43:37Z [Term] id: GO:2000227 name: negative regulation of pancreatic A cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic A cell differentiation." [GOC:mah] synonym: "negative regulation of pancreatic alpha cell differentiation" EXACT [GOC:obol] is_a: GO:0030857 ! negative regulation of epithelial cell differentiation is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:2000226 ! regulation of pancreatic A cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0003310 ! negatively regulates pancreatic A cell differentiation relationship: RO:0002212 GO:0003310 ! negatively regulates pancreatic A cell differentiation creation_date: 2010-11-09T03:43:40Z [Term] id: GO:2000228 name: positive regulation of pancreatic A cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of pancreatic A cell differentiation." [GOC:mah] synonym: "positive regulation of pancreatic alpha cell differentiation" EXACT [GOC:obol] is_a: GO:0030858 ! positive regulation of epithelial cell differentiation is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:2000226 ! regulation of pancreatic A cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0003310 ! positively regulates pancreatic A cell differentiation relationship: RO:0002213 GO:0003310 ! positively regulates pancreatic A cell differentiation creation_date: 2010-11-09T03:43:42Z [Term] id: GO:2000241 name: regulation of reproductive process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of reproductive process." [GOC:mah] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0022414 ! regulates (processual) reproductive process relationship: RO:0002211 GO:0022414 ! regulates (processual) reproductive process creation_date: 2010-11-10T02:44:02Z [Term] id: GO:2000242 name: negative regulation of reproductive process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of reproductive process." [GOC:mah] is_a: GO:0048519 ! negative regulation of biological process is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0022414 ! negatively regulates reproductive process relationship: RO:0002212 GO:0022414 ! negatively regulates reproductive process creation_date: 2010-11-10T02:44:05Z [Term] id: GO:2000243 name: positive regulation of reproductive process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of reproductive process." [GOC:mah] is_a: GO:0048518 ! positive regulation of biological process is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0022414 ! positively regulates reproductive process relationship: RO:0002213 GO:0022414 ! positively regulates reproductive process creation_date: 2010-11-10T02:44:08Z [Term] id: GO:2000248 name: negative regulation of establishment or maintenance of neuroblast polarity namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or maintenance of neuroblast polarity." [GOC:obol] synonym: "negative regulation of establishment and/or maintenance of neuroblast cell polarity" EXACT [GOC:obol] is_a: GO:0010454 ! negative regulation of cell fate commitment is_a: GO:0032878 ! regulation of establishment or maintenance of cell polarity is_a: GO:0045769 ! negative regulation of asymmetric cell division intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0045196 ! negatively regulates establishment or maintenance of neuroblast polarity relationship: RO:0002212 GO:0045196 ! negatively regulates establishment or maintenance of neuroblast polarity creation_date: 2010-11-11T11:40:34Z [Term] id: GO:2000254 name: regulation of male germ cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of male germ cell proliferation." [GOC:obol] is_a: GO:1905936 ! regulation of germ cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002176 ! regulates (processual) male germ cell proliferation relationship: RO:0002211 GO:0002176 ! regulates (processual) male germ cell proliferation creation_date: 2010-11-18T09:29:44Z [Term] id: GO:2000255 name: negative regulation of male germ cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of male germ cell proliferation." [GOC:obol] is_a: GO:1905937 ! negative regulation of germ cell proliferation is_a: GO:2000254 ! regulation of male germ cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002176 ! negatively regulates male germ cell proliferation relationship: RO:0002212 GO:0002176 ! negatively regulates male germ cell proliferation creation_date: 2010-11-18T09:29:47Z [Term] id: GO:2000256 name: positive regulation of male germ cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of male germ cell proliferation." [GOC:obol] is_a: GO:1905938 ! positive regulation of germ cell proliferation is_a: GO:2000254 ! regulation of male germ cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002176 ! positively regulates male germ cell proliferation relationship: RO:0002213 GO:0002176 ! positively regulates male germ cell proliferation creation_date: 2010-11-18T09:29:50Z [Term] id: GO:2000269 name: regulation of fibroblast apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of fibroblast apoptotic process." [GOC:mtg_apoptosis, GOC:obol, GOC:yaf] is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0044346 ! regulates (processual) fibroblast apoptotic process relationship: RO:0002211 GO:0044346 ! regulates (processual) fibroblast apoptotic process creation_date: 2010-11-23T01:07:23Z [Term] id: GO:2000270 name: negative regulation of fibroblast apoptotic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast apoptotic process." [GOC:mtg_apoptosis, GOC:obol, GOC:yaf] is_a: GO:0043066 ! negative regulation of apoptotic process is_a: GO:2000269 ! regulation of fibroblast apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0044346 ! negatively regulates fibroblast apoptotic process relationship: RO:0002212 GO:0044346 ! negatively regulates fibroblast apoptotic process creation_date: 2010-11-23T01:07:27Z [Term] id: GO:2000271 name: positive regulation of fibroblast apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of fibroblast apoptotic process." [GOC:mtg_apoptosis, GOC:obol, GOC:yaf] is_a: GO:0043065 ! positive regulation of apoptotic process is_a: GO:2000269 ! regulation of fibroblast apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0044346 ! positively regulates fibroblast apoptotic process relationship: RO:0002213 GO:0044346 ! positively regulates fibroblast apoptotic process creation_date: 2010-11-23T01:07:29Z [Term] id: GO:2000278 name: regulation of DNA biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of DNA biosynthetic process." [GOC:obol] synonym: "regulation of DNA anabolism" EXACT [GOC:obol] synonym: "regulation of DNA biosynthesis" EXACT [GOC:obol] synonym: "regulation of DNA formation" EXACT [GOC:obol] synonym: "regulation of DNA synthesis" EXACT [GOC:obol] is_a: GO:0010556 ! regulation of macromolecule biosynthetic process is_a: GO:0051052 ! regulation of DNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0071897 ! regulates (processual) DNA biosynthetic process relationship: RO:0002211 GO:0071897 ! regulates (processual) DNA biosynthetic process creation_date: 2010-12-08T04:48:15Z [Term] id: GO:2000279 name: negative regulation of DNA biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of DNA biosynthetic process." [GOC:obol] synonym: "negative regulation of DNA anabolism" EXACT [GOC:obol] synonym: "negative regulation of DNA biosynthesis" EXACT [GOC:obol] synonym: "negative regulation of DNA formation" EXACT [GOC:obol] synonym: "negative regulation of DNA synthesis" EXACT [GOC:obol] is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process is_a: GO:0051053 ! negative regulation of DNA metabolic process is_a: GO:2000278 ! regulation of DNA biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0071897 ! negatively regulates DNA biosynthetic process relationship: RO:0002212 GO:0071897 ! negatively regulates DNA biosynthetic process creation_date: 2010-12-08T04:48:20Z [Term] id: GO:2000282 name: regulation of cellular amino acid biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cellular amino acid biosynthetic process." [GOC:obol] synonym: "regulation of amino acid biosynthetic process" EXACT [GOC:obol] synonym: "regulation of cellular amino acid anabolism" EXACT [GOC:obol] synonym: "regulation of cellular amino acid biosynthesis" EXACT [GOC:obol] synonym: "regulation of cellular amino acid formation" EXACT [GOC:obol] synonym: "regulation of cellular amino acid synthesis" EXACT [GOC:obol] is_a: GO:0031326 ! regulation of cellular biosynthetic process is_a: GO:0051171 ! regulation of nitrogen compound metabolic process is_a: GO:0062012 ! regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0008652 ! regulates (processual) amino acid biosynthetic process relationship: RO:0002211 GO:0008652 ! regulates (processual) amino acid biosynthetic process creation_date: 2010-12-10T11:54:19Z [Term] id: GO:2000283 name: negative regulation of amino acid biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of an amino acid biosynthetic process." [GOC:obol] synonym: "negative regulation of amino acid anabolism" EXACT [GOC:obol] synonym: "negative regulation of amino acid biosynthesis" EXACT [GOC:obol] synonym: "negative regulation of amino acid formation" EXACT [GOC:obol] synonym: "negative regulation of amino acid synthesis" EXACT [GOC:obol] synonym: "negative regulation of cellular amino acid biosynthetic process" EXACT [GOC:obol] is_a: GO:0031327 ! negative regulation of cellular biosynthetic process is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process is_a: GO:0062014 ! negative regulation of small molecule metabolic process is_a: GO:2000282 ! regulation of cellular amino acid biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0008652 ! negatively regulates amino acid biosynthetic process relationship: RO:0002212 GO:0008652 ! negatively regulates amino acid biosynthetic process creation_date: 2010-12-10T11:54:23Z [Term] id: GO:2000284 name: positive regulation of amino acid biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cellular amino acid biosynthetic process." [GOC:obol] synonym: "positive regulation of amino acid anabolism" EXACT [GOC:obol] synonym: "positive regulation of amino acid biosynthesis" EXACT [GOC:obol] synonym: "positive regulation of amino acid formation" EXACT [GOC:obol] synonym: "positive regulation of amino acid synthesis" EXACT [GOC:obol] synonym: "positive regulation of cellular amino acid biosynthetic process" EXACT [GOC:obol] is_a: GO:0031328 ! positive regulation of cellular biosynthetic process is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process is_a: GO:0062013 ! positive regulation of small molecule metabolic process is_a: GO:2000282 ! regulation of cellular amino acid biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0008652 ! positively regulates amino acid biosynthetic process relationship: RO:0002213 GO:0008652 ! positively regulates amino acid biosynthetic process creation_date: 2010-12-10T11:54:27Z [Term] id: GO:2000287 name: positive regulation of myotome development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of myotome development." [GOC:BHF] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:2000290 ! regulation of myotome development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0061055 ! positively regulates myotome development relationship: RO:0002213 GO:0061055 ! positively regulates myotome development creation_date: 2010-12-16T05:17:15Z [Term] id: GO:2000288 name: positive regulation of myoblast proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of myoblast proliferation." [GOC:BHF] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:2000291 ! regulation of myoblast proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0051450 ! positively regulates myoblast proliferation relationship: RO:0002213 GO:0051450 ! positively regulates myoblast proliferation creation_date: 2010-12-16T05:20:52Z [Term] id: GO:2000290 name: regulation of myotome development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of myotome development." [GOC:mah] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0061055 ! regulates (processual) myotome development relationship: RO:0002211 GO:0061055 ! regulates (processual) myotome development creation_date: 2010-12-20T10:22:05Z [Term] id: GO:2000291 name: regulation of myoblast proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of myoblast proliferation." [GOC:mah] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0051450 ! regulates (processual) myoblast proliferation relationship: RO:0002211 GO:0051450 ! regulates (processual) myoblast proliferation creation_date: 2010-12-20T10:34:26Z [Term] id: GO:2000292 name: regulation of defecation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of defecation." [GOC:obol] is_a: GO:0044058 ! regulation of digestive system process is_a: GO:0044062 ! regulation of excretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030421 ! regulates (processual) defecation relationship: RO:0002211 GO:0030421 ! regulates (processual) defecation creation_date: 2010-12-21T09:23:08Z [Term] id: GO:2000293 name: negative regulation of defecation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of defecation." [GOC:obol] is_a: GO:0051048 ! negative regulation of secretion is_a: GO:0060457 ! negative regulation of digestive system process is_a: GO:2000292 ! regulation of defecation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030421 ! negatively regulates defecation relationship: RO:0002212 GO:0030421 ! negatively regulates defecation creation_date: 2010-12-21T09:23:13Z [Term] id: GO:2000294 name: positive regulation of defecation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of defecation." [GOC:obol] is_a: GO:0051047 ! positive regulation of secretion is_a: GO:0060456 ! positive regulation of digestive system process is_a: GO:2000292 ! regulation of defecation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030421 ! positively regulates defecation relationship: RO:0002213 GO:0030421 ! positively regulates defecation creation_date: 2010-12-21T09:23:16Z [Term] id: GO:2000351 name: regulation of endothelial cell apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of endothelial cell apoptotic process." [GOC:mah, GOC:mtg_apoptosis] synonym: "regulation of apoptosis of endothelial cells" EXACT [GOC:obol] synonym: "regulation of endothelial cell programmed cell death by apoptosis" EXACT [GOC:obol] synonym: "regulation of killing of endothelial cells" EXACT [GOC:obol] synonym: "regulation of programmed cell death of endothelial cells by apoptosis" EXACT [GOC:obol] synonym: "regulation of programmed cell death, endothelial cells" EXACT [GOC:obol] is_a: GO:1904035 ! regulation of epithelial cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0072577 ! regulates (processual) endothelial cell apoptotic process relationship: RO:0002211 GO:0072577 ! regulates (processual) endothelial cell apoptotic process creation_date: 2011-02-03T10:43:16Z [Term] id: GO:2000352 name: negative regulation of endothelial cell apoptotic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell apoptotic process." [GOC:BHF, GOC:mah, GOC:mtg_apoptosis] synonym: "negative regulation of apoptosis of endothelial cells" EXACT [GOC:obol] synonym: "negative regulation of endothelial cell programmed cell death by apoptosis" EXACT [GOC:obol] synonym: "negative regulation of killing of endothelial cells" EXACT [GOC:obol] synonym: "negative regulation of programmed cell death of endothelial cells by apoptosis" EXACT [GOC:obol] synonym: "negative regulation of programmed cell death, endothelial cells" EXACT [GOC:obol] is_a: GO:1904036 ! negative regulation of epithelial cell apoptotic process is_a: GO:2000351 ! regulation of endothelial cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0072577 ! negatively regulates endothelial cell apoptotic process relationship: RO:0002212 GO:0072577 ! negatively regulates endothelial cell apoptotic process creation_date: 2011-02-03T10:43:20Z [Term] id: GO:2000353 name: positive regulation of endothelial cell apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of endothelial cell apoptotic process." [GOC:BHF, GOC:mah, GOC:mtg_apoptosis] synonym: "positive regulation of apoptosis of endothelial cells" EXACT [GOC:obol] synonym: "positive regulation of endothelial cell programmed cell death by apoptosis" EXACT [GOC:obol] synonym: "positive regulation of killing of endothelial cells" EXACT [GOC:obol] synonym: "positive regulation of programmed cell death of endothelial cells by apoptosis" EXACT [GOC:obol] synonym: "positive regulation of programmed cell death, endothelial cells" EXACT [GOC:obol] is_a: GO:1904037 ! positive regulation of epithelial cell apoptotic process is_a: GO:2000351 ! regulation of endothelial cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0072577 ! positively regulates endothelial cell apoptotic process relationship: RO:0002213 GO:0072577 ! positively regulates endothelial cell apoptotic process creation_date: 2011-02-03T10:43:23Z [Term] id: GO:2000374 name: regulation of oxygen metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of oxygen metabolic process." [GOC:mah] synonym: "regulation of diatomic oxygen metabolic process" EXACT [GOC:obol] synonym: "regulation of oxygen metabolism" EXACT [GOC:obol] is_a: GO:0031323 ! regulation of cellular metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0072592 ! regulates (processual) oxygen metabolic process relationship: RO:0002211 GO:0072592 ! regulates (processual) oxygen metabolic process creation_date: 2011-02-11T02:03:32Z [Term] id: GO:2000375 name: negative regulation of oxygen metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of oxygen metabolic process." [GOC:mah] synonym: "negative regulation of diatomic oxygen metabolic process" EXACT [GOC:obol] synonym: "negative regulation of oxygen metabolism" EXACT [GOC:obol] is_a: GO:0031324 ! negative regulation of cellular metabolic process is_a: GO:2000374 ! regulation of oxygen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0072592 ! negatively regulates oxygen metabolic process relationship: RO:0002212 GO:0072592 ! negatively regulates oxygen metabolic process creation_date: 2011-02-11T02:03:44Z [Term] id: GO:2000376 name: positive regulation of oxygen metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of oxygen metabolic process." [GOC:mah] synonym: "positive regulation of diatomic oxygen metabolic process" EXACT [GOC:obol] synonym: "positive regulation of oxygen metabolism" EXACT [GOC:obol] is_a: GO:0031325 ! positive regulation of cellular metabolic process is_a: GO:2000374 ! regulation of oxygen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0072592 ! positively regulates oxygen metabolic process relationship: RO:0002213 GO:0072592 ! positively regulates oxygen metabolic process creation_date: 2011-02-11T02:03:52Z [Term] id: GO:2000380 name: regulation of mesoderm development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mesoderm development." [GOC:BHF] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007498 ! regulates (processual) mesoderm development relationship: RO:0002211 GO:0007498 ! regulates (processual) mesoderm development creation_date: 2011-02-15T03:09:46Z [Term] id: GO:2000381 name: negative regulation of mesoderm development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm development." [GOC:BHF] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:2000380 ! regulation of mesoderm development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007498 ! negatively regulates mesoderm development relationship: RO:0002212 GO:0007498 ! negatively regulates mesoderm development creation_date: 2011-02-15T03:10:02Z [Term] id: GO:2000382 name: positive regulation of mesoderm development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mesoderm development." [GOC:BHF] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:2000380 ! regulation of mesoderm development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007498 ! positively regulates mesoderm development relationship: RO:0002213 GO:0007498 ! positively regulates mesoderm development creation_date: 2011-02-15T03:10:12Z [Term] id: GO:2000383 name: regulation of ectoderm development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of ectoderm development." [GOC:BHF] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007398 ! regulates (processual) ectoderm development relationship: RO:0002211 GO:0007398 ! regulates (processual) ectoderm development creation_date: 2011-02-15T03:17:10Z [Term] id: GO:2000384 name: negative regulation of ectoderm development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of ectoderm development." [GOC:BHF] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:2000383 ! regulation of ectoderm development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007398 ! negatively regulates ectoderm development relationship: RO:0002212 GO:0007398 ! negatively regulates ectoderm development creation_date: 2011-02-15T03:17:27Z [Term] id: GO:2000385 name: positive regulation of ectoderm development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of ectoderm development." [GOC:BHF] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:2000383 ! regulation of ectoderm development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007398 ! positively regulates ectoderm development relationship: RO:0002213 GO:0007398 ! positively regulates ectoderm development creation_date: 2011-02-15T03:17:39Z [Term] id: GO:2000401 name: regulation of lymphocyte migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of lymphocyte migration." [GOC:mah] is_a: GO:0071675 ! regulation of mononuclear cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0072676 ! regulates (processual) lymphocyte migration relationship: RO:0002211 GO:0072676 ! regulates (processual) lymphocyte migration creation_date: 2011-02-23T10:45:19Z [Term] id: GO:2000402 name: negative regulation of lymphocyte migration namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte migration." [GOC:mah] is_a: GO:0071676 ! negative regulation of mononuclear cell migration is_a: GO:2000401 ! regulation of lymphocyte migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0072676 ! negatively regulates lymphocyte migration relationship: RO:0002212 GO:0072676 ! negatively regulates lymphocyte migration creation_date: 2011-02-23T10:45:47Z [Term] id: GO:2000403 name: positive regulation of lymphocyte migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of lymphocyte migration." [GOC:mah] is_a: GO:0071677 ! positive regulation of mononuclear cell migration is_a: GO:2000401 ! regulation of lymphocyte migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0072676 ! positively regulates lymphocyte migration relationship: RO:0002213 GO:0072676 ! positively regulates lymphocyte migration creation_date: 2011-02-23T10:46:06Z [Term] id: GO:2000404 name: regulation of T cell migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of T cell migration." [GOC:mah] synonym: "regulation of T lymphocyte migration" EXACT [GOC:obol] synonym: "regulation of T-cell migration" EXACT [GOC:obol] synonym: "regulation of T-lymphocyte migration" EXACT [GOC:obol] is_a: GO:2000401 ! regulation of lymphocyte migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0072678 ! regulates (processual) T cell migration relationship: RO:0002211 GO:0072678 ! regulates (processual) T cell migration creation_date: 2011-02-23T10:48:24Z [Term] id: GO:2000405 name: negative regulation of T cell migration namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of T cell migration." [GOC:mah] synonym: "negative regulation of T lymphocyte migration" EXACT [GOC:obol] synonym: "negative regulation of T-cell migration" EXACT [GOC:obol] synonym: "negative regulation of T-lymphocyte migration" EXACT [GOC:obol] is_a: GO:2000402 ! negative regulation of lymphocyte migration is_a: GO:2000404 ! regulation of T cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0072678 ! negatively regulates T cell migration relationship: RO:0002212 GO:0072678 ! negatively regulates T cell migration creation_date: 2011-02-23T10:48:52Z [Term] id: GO:2000406 name: positive regulation of T cell migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of T cell migration." [GOC:mah] synonym: "positive regulation of T lymphocyte migration" EXACT [GOC:obol] synonym: "positive regulation of T-cell migration" EXACT [GOC:obol] synonym: "positive regulation of T-lymphocyte migration" EXACT [GOC:obol] is_a: GO:2000403 ! positive regulation of lymphocyte migration is_a: GO:2000404 ! regulation of T cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0072678 ! positively regulates T cell migration relationship: RO:0002213 GO:0072678 ! positively regulates T cell migration creation_date: 2011-02-23T10:49:12Z [Term] id: GO:2000471 name: regulation of hematopoietic stem cell migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of hematopoietic stem cell migration." [GOC:obol] synonym: "regulation of hemopoietic stem cell migration" EXACT [GOC:obol] is_a: GO:0030334 ! regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0035701 ! regulates (processual) hematopoietic stem cell migration relationship: RO:0002211 GO:0035701 ! regulates (processual) hematopoietic stem cell migration creation_date: 2011-03-09T09:34:08Z [Term] id: GO:2000472 name: negative regulation of hematopoietic stem cell migration namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell migration." [GOC:obol] synonym: "negative regulation of hemopoietic stem cell migration" EXACT [GOC:obol] is_a: GO:0030336 ! negative regulation of cell migration is_a: GO:2000471 ! regulation of hematopoietic stem cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0035701 ! negatively regulates hematopoietic stem cell migration relationship: RO:0002212 GO:0035701 ! negatively regulates hematopoietic stem cell migration creation_date: 2011-03-09T09:34:54Z [Term] id: GO:2000473 name: positive regulation of hematopoietic stem cell migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell migration." [GOC:obol] synonym: "positive regulation of hemopoietic stem cell migration" EXACT [GOC:obol] is_a: GO:0030335 ! positive regulation of cell migration is_a: GO:2000471 ! regulation of hematopoietic stem cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0035701 ! positively regulates hematopoietic stem cell migration relationship: RO:0002213 GO:0035701 ! positively regulates hematopoietic stem cell migration creation_date: 2011-03-09T09:35:25Z [Term] id: GO:2000495 name: regulation of cell proliferation involved in compound eye morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis." [GOC:obol] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0035736 ! regulates (processual) cell proliferation involved in compound eye morphogenesis relationship: RO:0002211 GO:0035736 ! regulates (processual) cell proliferation involved in compound eye morphogenesis creation_date: 2011-03-18T02:18:34Z [Term] id: GO:2000496 name: negative regulation of cell proliferation involved in compound eye morphogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis." [GOC:obol] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:2000495 ! regulation of cell proliferation involved in compound eye morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0035736 ! negatively regulates cell proliferation involved in compound eye morphogenesis relationship: RO:0002212 GO:0035736 ! negatively regulates cell proliferation involved in compound eye morphogenesis creation_date: 2011-03-18T02:19:22Z [Term] id: GO:2000497 name: positive regulation of cell proliferation involved in compound eye morphogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis." [GOC:obol] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:2000495 ! regulation of cell proliferation involved in compound eye morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0035736 ! positively regulates cell proliferation involved in compound eye morphogenesis relationship: RO:0002213 GO:0035736 ! positively regulates cell proliferation involved in compound eye morphogenesis creation_date: 2011-03-18T02:19:54Z [Term] id: GO:2000542 name: negative regulation of gastrulation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of gastrulation." [GOC:obol] is_a: GO:0010470 ! regulation of gastrulation is_a: GO:0045992 ! negative regulation of embryonic development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007369 ! negatively regulates gastrulation relationship: RO:0002212 GO:0007369 ! negatively regulates gastrulation creation_date: 2011-04-01T04:10:08Z [Term] id: GO:2000543 name: positive regulation of gastrulation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of gastrulation." [GOC:obol] is_a: GO:0010470 ! regulation of gastrulation is_a: GO:0040019 ! positive regulation of embryonic development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007369 ! positively regulates gastrulation relationship: RO:0002213 GO:0007369 ! positively regulates gastrulation creation_date: 2011-04-01T04:10:15Z [Term] id: GO:2000547 name: regulation of dendritic cell dendrite assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of dendritic cell dendrite assembly." [GOC:obol] is_a: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0097026 ! regulates (processual) dendritic cell dendrite assembly relationship: RO:0002211 GO:0097026 ! regulates (processual) dendritic cell dendrite assembly creation_date: 2011-04-03T07:21:55Z [Term] id: GO:2000548 name: negative regulation of dendritic cell dendrite assembly namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell dendrite assembly." [GOC:obol] is_a: GO:0120033 ! negative regulation of plasma membrane bounded cell projection assembly is_a: GO:2000547 ! regulation of dendritic cell dendrite assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0097026 ! negatively regulates dendritic cell dendrite assembly relationship: RO:0002212 GO:0097026 ! negatively regulates dendritic cell dendrite assembly creation_date: 2011-04-03T07:22:01Z [Term] id: GO:2000549 name: positive regulation of dendritic cell dendrite assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of dendritic cell dendrite assembly." [GOC:obol] is_a: GO:0120034 ! positive regulation of plasma membrane bounded cell projection assembly is_a: GO:2000547 ! regulation of dendritic cell dendrite assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0097026 ! positively regulates dendritic cell dendrite assembly relationship: RO:0002213 GO:0097026 ! positively regulates dendritic cell dendrite assembly creation_date: 2011-04-03T07:22:06Z [Term] id: GO:2000573 name: positive regulation of DNA biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of DNA biosynthetic process." [GOC:obol] synonym: "positive regulation of DNA anabolism" EXACT [GOC:obol] synonym: "positive regulation of DNA biosynthesis" EXACT [GOC:obol] synonym: "positive regulation of DNA formation" EXACT [GOC:obol] synonym: "positive regulation of DNA synthesis" EXACT [GOC:obol] is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process is_a: GO:0051054 ! positive regulation of DNA metabolic process is_a: GO:2000278 ! regulation of DNA biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0071897 ! positively regulates DNA biosynthetic process relationship: RO:0002213 GO:0071897 ! positively regulates DNA biosynthetic process creation_date: 2011-04-04T10:01:20Z [Term] id: GO:2000606 name: regulation of cell proliferation involved in mesonephros development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell proliferation involved in mesonephros development." [GOC:obol] is_a: GO:1901722 ! regulation of cell proliferation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0061209 ! regulates (processual) cell proliferation involved in mesonephros development relationship: RO:0002211 GO:0061209 ! regulates (processual) cell proliferation involved in mesonephros development creation_date: 2011-04-18T08:42:19Z [Term] id: GO:2000607 name: negative regulation of cell proliferation involved in mesonephros development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in mesonephros development." [GOC:obol] is_a: GO:1901723 ! negative regulation of cell proliferation involved in kidney development is_a: GO:2000606 ! regulation of cell proliferation involved in mesonephros development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0061209 ! negatively regulates cell proliferation involved in mesonephros development relationship: RO:0002212 GO:0061209 ! negatively regulates cell proliferation involved in mesonephros development creation_date: 2011-04-18T08:42:23Z [Term] id: GO:2000608 name: positive regulation of cell proliferation involved in mesonephros development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell proliferation involved in mesonephros development." [GOC:obol] is_a: GO:1901724 ! positive regulation of cell proliferation involved in kidney development is_a: GO:2000606 ! regulation of cell proliferation involved in mesonephros development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0061209 ! positively regulates cell proliferation involved in mesonephros development relationship: RO:0002213 GO:0061209 ! positively regulates cell proliferation involved in mesonephros development creation_date: 2011-04-18T08:42:25Z [Term] id: GO:2000647 name: negative regulation of stem cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of stem cell proliferation." [GOC:dph] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0072091 ! regulation of stem cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0072089 ! negatively regulates stem cell proliferation relationship: RO:0002212 GO:0072089 ! negatively regulates stem cell proliferation creation_date: 2011-04-27T01:04:22Z [Term] id: GO:2000648 name: positive regulation of stem cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of stem cell proliferation." [GOC:dph] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0072091 ! regulation of stem cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0072089 ! positively regulates stem cell proliferation relationship: RO:0002213 GO:0072089 ! positively regulates stem cell proliferation creation_date: 2011-04-27T01:04:25Z [Term] id: GO:2000649 name: regulation of sodium ion transmembrane transporter activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of sodium ion transmembrane transporter activity." [GOC:obol] synonym: "regulation of sodium transporter activity" EXACT [GOC:obol] is_a: GO:0032412 ! regulation of monoatomic ion transmembrane transporter activity is_a: GO:1902305 ! regulation of sodium ion transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0015081 ! regulates (processual) sodium ion transmembrane transporter activity relationship: RO:0002211 GO:0015081 ! regulates (processual) sodium ion transmembrane transporter activity creation_date: 2011-04-28T08:42:53Z [Term] id: GO:2000650 name: negative regulation of sodium ion transmembrane transporter activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transporter activity." [GOC:obol] synonym: "negative regulation of sodium transporter activity" EXACT [GOC:obol] is_a: GO:0032413 ! negative regulation of ion transmembrane transporter activity is_a: GO:1902306 ! negative regulation of sodium ion transmembrane transport is_a: GO:2000649 ! regulation of sodium ion transmembrane transporter activity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0015081 ! negatively regulates sodium ion transmembrane transporter activity relationship: RO:0002212 GO:0015081 ! negatively regulates sodium ion transmembrane transporter activity creation_date: 2011-04-28T08:42:57Z [Term] id: GO:2000651 name: positive regulation of sodium ion transmembrane transporter activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transporter activity." [GOC:obol] synonym: "positive regulation of sodium transporter activity" EXACT [GOC:obol] is_a: GO:0032414 ! positive regulation of ion transmembrane transporter activity is_a: GO:1902307 ! positive regulation of sodium ion transmembrane transport is_a: GO:2000649 ! regulation of sodium ion transmembrane transporter activity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0015081 ! positively regulates sodium ion transmembrane transporter activity relationship: RO:0002213 GO:0015081 ! positively regulates sodium ion transmembrane transporter activity creation_date: 2011-04-28T08:43:00Z [Term] id: GO:2000668 name: regulation of dendritic cell apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of dendritic cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] is_a: GO:2000106 ! regulation of leukocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0097048 ! regulates (processual) dendritic cell apoptotic process relationship: RO:0002211 GO:0097048 ! regulates (processual) dendritic cell apoptotic process creation_date: 2011-05-09T07:34:16Z [Term] id: GO:2000669 name: negative regulation of dendritic cell apoptotic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] is_a: GO:2000107 ! negative regulation of leukocyte apoptotic process is_a: GO:2000668 ! regulation of dendritic cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0097048 ! negatively regulates dendritic cell apoptotic process relationship: RO:0002212 GO:0097048 ! negatively regulates dendritic cell apoptotic process creation_date: 2011-05-09T07:34:21Z [Term] id: GO:2000670 name: positive regulation of dendritic cell apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of dendritic cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] is_a: GO:2000108 ! positive regulation of leukocyte apoptotic process is_a: GO:2000668 ! regulation of dendritic cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0097048 ! positively regulates dendritic cell apoptotic process relationship: RO:0002213 GO:0097048 ! positively regulates dendritic cell apoptotic process creation_date: 2011-05-09T07:34:26Z [Term] id: GO:2000671 name: regulation of motor neuron apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of motor neuron apoptotic process." [GOC:mtg_apoptosis, GOC:obol] synonym: "regulation of motoneuron apoptosis" EXACT [GOC:obol] is_a: GO:0043523 ! regulation of neuron apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0097049 ! regulates (processual) motor neuron apoptotic process relationship: RO:0002211 GO:0097049 ! regulates (processual) motor neuron apoptotic process creation_date: 2011-05-09T10:56:17Z [Term] id: GO:2000672 name: negative regulation of motor neuron apoptotic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron apoptotic process." [GOC:mtg_apoptosis, GOC:obol] synonym: "negative regulation of motoneuron apoptosis" EXACT [GOC:obol] is_a: GO:0043524 ! negative regulation of neuron apoptotic process is_a: GO:2000671 ! regulation of motor neuron apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0097049 ! negatively regulates motor neuron apoptotic process relationship: RO:0002212 GO:0097049 ! negatively regulates motor neuron apoptotic process creation_date: 2011-05-09T10:56:21Z [Term] id: GO:2000673 name: positive regulation of motor neuron apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of motor neuron apoptotic process." [GOC:mtg_apoptosis, GOC:obol] synonym: "positive regulation of motoneuron apoptosis" EXACT [GOC:obol] is_a: GO:0043525 ! positive regulation of neuron apoptotic process is_a: GO:2000671 ! regulation of motor neuron apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0097049 ! positively regulates motor neuron apoptotic process relationship: RO:0002213 GO:0097049 ! positively regulates motor neuron apoptotic process creation_date: 2011-05-09T10:56:24Z [Term] id: GO:2000674 name: regulation of type B pancreatic cell apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of type B pancreatic cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] synonym: "regulation of pancreatic B cell apoptosis" EXACT [GOC:obol] synonym: "regulation of pancreatic beta cell apoptosis" EXACT [GOC:obol] is_a: GO:1904035 ! regulation of epithelial cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0097050 ! regulates (processual) type B pancreatic cell apoptotic process relationship: RO:0002211 GO:0097050 ! regulates (processual) type B pancreatic cell apoptotic process creation_date: 2011-05-09T11:51:09Z [Term] id: GO:2000675 name: negative regulation of type B pancreatic cell apoptotic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] synonym: "negative regulation of pancreatic B cell apoptosis" EXACT [GOC:obol] synonym: "negative regulation of pancreatic beta cell apoptosis" EXACT [GOC:obol] is_a: GO:1904036 ! negative regulation of epithelial cell apoptotic process is_a: GO:2000674 ! regulation of type B pancreatic cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0097050 ! negatively regulates type B pancreatic cell apoptotic process relationship: RO:0002212 GO:0097050 ! negatively regulates type B pancreatic cell apoptotic process creation_date: 2011-05-09T11:51:12Z [Term] id: GO:2000676 name: positive regulation of type B pancreatic cell apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of type B pancreatic cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] synonym: "positive regulation of pancreatic B cell apoptosis" EXACT [GOC:obol] synonym: "positive regulation of pancreatic beta cell apoptosis" EXACT [GOC:obol] is_a: GO:1904037 ! positive regulation of epithelial cell apoptotic process is_a: GO:2000674 ! regulation of type B pancreatic cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0097050 ! positively regulates type B pancreatic cell apoptotic process relationship: RO:0002213 GO:0097050 ! positively regulates type B pancreatic cell apoptotic process creation_date: 2011-05-09T11:51:15Z [Term] id: GO:2000690 name: regulation of cardiac muscle cell myoblast differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac muscle cell myoblast differentiation." [GOC:obol] synonym: "regulation of myocardial precursor cell differentiation" EXACT [GOC:obol] is_a: GO:0045661 ! regulation of myoblast differentiation is_a: GO:0051890 ! regulation of cardioblast differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060379 ! regulates (processual) cardiac muscle cell myoblast differentiation relationship: RO:0002211 GO:0060379 ! regulates (processual) cardiac muscle cell myoblast differentiation creation_date: 2011-05-25T09:08:01Z [Term] id: GO:2000691 name: negative regulation of cardiac muscle cell myoblast differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell myoblast differentiation." [GOC:obol] synonym: "negative regulation of myocardial precursor cell differentiation" EXACT [GOC:obol] is_a: GO:0045662 ! negative regulation of myoblast differentiation is_a: GO:0051892 ! negative regulation of cardioblast differentiation is_a: GO:2000690 ! regulation of cardiac muscle cell myoblast differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060379 ! negatively regulates cardiac muscle cell myoblast differentiation relationship: RO:0002212 GO:0060379 ! negatively regulates cardiac muscle cell myoblast differentiation creation_date: 2011-05-25T09:08:06Z [Term] id: GO:2000696 name: regulation of epithelial cell differentiation involved in kidney development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of epithelial cell differentiation involved in kidney development." [GOC:mtg_kidney_jan10, GOC:yaf] is_a: GO:0030856 ! regulation of epithelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0035850 ! regulates (processual) epithelial cell differentiation involved in kidney development relationship: RO:0002211 GO:0035850 ! regulates (processual) epithelial cell differentiation involved in kidney development creation_date: 2011-05-16T04:23:52Z [Term] id: GO:2000697 name: negative regulation of epithelial cell differentiation involved in kidney development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell differentiation involved in kidney development." [GOC:mtg_kidney_jan10, GOC:yaf] is_a: GO:0030857 ! negative regulation of epithelial cell differentiation is_a: GO:2000696 ! regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0035850 ! negatively regulates epithelial cell differentiation involved in kidney development relationship: RO:0002212 GO:0035850 ! negatively regulates epithelial cell differentiation involved in kidney development creation_date: 2011-05-16T04:23:55Z [Term] id: GO:2000698 name: positive regulation of epithelial cell differentiation involved in kidney development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation involved in kidney development." [GOC:mtg_kidney_jan10, GOC:yaf] is_a: GO:0030858 ! positive regulation of epithelial cell differentiation is_a: GO:2000696 ! regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0035850 ! positively regulates epithelial cell differentiation involved in kidney development relationship: RO:0002213 GO:0035850 ! positively regulates epithelial cell differentiation involved in kidney development creation_date: 2011-05-16T04:23:57Z [Term] id: GO:2000700 name: positive regulation of cardiac muscle cell myoblast differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cardiac muscle cell myoblast differentiation." [GOC:obol] synonym: "positive regulation of myocardial precursor cell differentiation" EXACT [GOC:obol] is_a: GO:0045663 ! positive regulation of myoblast differentiation is_a: GO:0051891 ! positive regulation of cardioblast differentiation is_a: GO:2000690 ! regulation of cardiac muscle cell myoblast differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060379 ! positively regulates cardiac muscle cell myoblast differentiation relationship: RO:0002213 GO:0060379 ! positively regulates cardiac muscle cell myoblast differentiation creation_date: 2011-05-25T09:08:09Z [Term] id: GO:2000725 name: regulation of cardiac muscle cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac muscle cell differentiation." [GOC:BHF] synonym: "regulation of cardiomyocyte differentiation" EXACT [GOC:obol] is_a: GO:0051153 ! regulation of striated muscle cell differentiation is_a: GO:1905207 ! regulation of cardiocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0055007 ! regulates (processual) cardiac muscle cell differentiation relationship: RO:0002211 GO:0055007 ! regulates (processual) cardiac muscle cell differentiation creation_date: 2011-06-08T10:51:06Z [Term] id: GO:2000726 name: negative regulation of cardiac muscle cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell differentiation." [GOC:BHF] synonym: "negative regulation of cardiomyocyte differentiation" EXACT [GOC:obol] is_a: GO:0051154 ! negative regulation of striated muscle cell differentiation is_a: GO:1905208 ! negative regulation of cardiocyte differentiation is_a: GO:2000725 ! regulation of cardiac muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0055007 ! negatively regulates cardiac muscle cell differentiation relationship: RO:0002212 GO:0055007 ! negatively regulates cardiac muscle cell differentiation creation_date: 2011-06-08T10:51:11Z [Term] id: GO:2000727 name: positive regulation of cardiac muscle cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cardiac muscle cell differentiation." [GOC:BHF] synonym: "positive regulation of cardiomyocyte differentiation" EXACT [GOC:obol] is_a: GO:0051155 ! positive regulation of striated muscle cell differentiation is_a: GO:1905209 ! positive regulation of cardiocyte differentiation is_a: GO:2000725 ! regulation of cardiac muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0055007 ! positively regulates cardiac muscle cell differentiation relationship: RO:0002213 GO:0055007 ! positively regulates cardiac muscle cell differentiation creation_date: 2011-06-08T10:51:15Z [Term] id: GO:2000729 name: positive regulation of mesenchymal cell proliferation involved in ureter development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in ureter development." [GOC:obol] is_a: GO:0002053 ! positive regulation of mesenchymal cell proliferation is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0072199 ! regulation of mesenchymal cell proliferation involved in ureter development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0072198 ! positively regulates mesenchymal cell proliferation involved in ureter development relationship: RO:0002213 GO:0072198 ! positively regulates mesenchymal cell proliferation involved in ureter development creation_date: 2011-06-10T02:27:19Z [Term] id: GO:2000736 name: regulation of stem cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of stem cell differentiation." [GOC:obol] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048863 ! regulates (processual) stem cell differentiation relationship: RO:0002211 GO:0048863 ! regulates (processual) stem cell differentiation creation_date: 2011-06-14T02:05:16Z [Term] id: GO:2000737 name: negative regulation of stem cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation." [GOC:obol] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:2000736 ! regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048863 ! negatively regulates stem cell differentiation relationship: RO:0002212 GO:0048863 ! negatively regulates stem cell differentiation creation_date: 2011-06-14T02:05:20Z [Term] id: GO:2000738 name: positive regulation of stem cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of stem cell differentiation." [GOC:obol] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:2000736 ! regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0048863 ! positively regulates stem cell differentiation relationship: RO:0002213 GO:0048863 ! positively regulates stem cell differentiation creation_date: 2011-06-14T02:05:23Z [Term] id: GO:2000768 name: positive regulation of nephron tubule epithelial cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of nephron tubule epithelial cell differentiation." [GOC:obol] is_a: GO:0072182 ! regulation of nephron tubule epithelial cell differentiation is_a: GO:2000698 ! positive regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0072160 ! positively regulates nephron tubule epithelial cell differentiation relationship: RO:0002213 GO:0072160 ! positively regulates nephron tubule epithelial cell differentiation creation_date: 2011-06-22T11:55:06Z [Term] id: GO:2000790 name: regulation of mesenchymal cell proliferation involved in lung development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation involved in lung development." [PMID:21513708] is_a: GO:0010464 ! regulation of mesenchymal cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060916 ! regulates (processual) mesenchymal cell proliferation involved in lung development relationship: RO:0002211 GO:0060916 ! regulates (processual) mesenchymal cell proliferation involved in lung development creation_date: 2011-06-24T01:53:50Z [Term] id: GO:2000791 name: negative regulation of mesenchymal cell proliferation involved in lung development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell proliferation involved in lung development." [PMID:21513708] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:0072201 ! negative regulation of mesenchymal cell proliferation is_a: GO:2000790 ! regulation of mesenchymal cell proliferation involved in lung development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060916 ! negatively regulates mesenchymal cell proliferation involved in lung development relationship: RO:0002212 GO:0060916 ! negatively regulates mesenchymal cell proliferation involved in lung development creation_date: 2011-06-24T01:53:53Z [Term] id: GO:2000792 name: positive regulation of mesenchymal cell proliferation involved in lung development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in lung development." [PMID:21513708] is_a: GO:0002053 ! positive regulation of mesenchymal cell proliferation is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:2000790 ! regulation of mesenchymal cell proliferation involved in lung development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060916 ! positively regulates mesenchymal cell proliferation involved in lung development relationship: RO:0002213 GO:0060916 ! positively regulates mesenchymal cell proliferation involved in lung development creation_date: 2011-06-24T01:53:56Z [Term] id: GO:2000794 name: regulation of epithelial cell proliferation involved in lung morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis." [PMID:21513708] is_a: GO:0050678 ! regulation of epithelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060502 ! regulates (processual) epithelial cell proliferation involved in lung morphogenesis relationship: RO:0002211 GO:0060502 ! regulates (processual) epithelial cell proliferation involved in lung morphogenesis creation_date: 2011-06-25T07:22:38Z [Term] id: GO:2000795 name: negative regulation of epithelial cell proliferation involved in lung morphogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis." [PMID:21513708] is_a: GO:0050680 ! negative regulation of epithelial cell proliferation is_a: GO:2000794 ! regulation of epithelial cell proliferation involved in lung morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060502 ! negatively regulates epithelial cell proliferation involved in lung morphogenesis relationship: RO:0002212 GO:0060502 ! negatively regulates epithelial cell proliferation involved in lung morphogenesis creation_date: 2011-06-25T07:22:42Z [Term] id: GO:2000818 name: negative regulation of myoblast proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of myoblast proliferation." [GOC:obol] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:2000291 ! regulation of myoblast proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0051450 ! negatively regulates myoblast proliferation relationship: RO:0002212 GO:0051450 ! negatively regulates myoblast proliferation creation_date: 2011-07-12T03:06:04Z [Term] id: GO:2000826 name: regulation of heart morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of heart morphogenesis." [GOC:BHF] is_a: GO:2000027 ! regulation of animal organ morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003007 ! regulates (processual) heart morphogenesis relationship: RO:0002211 GO:0003007 ! regulates (processual) heart morphogenesis creation_date: 2011-07-19T10:08:58Z [Term] id: GO:2000831 name: regulation of steroid hormone secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of steroid hormone secretion." [GOC:sl] is_a: GO:0032368 ! regulation of lipid transport is_a: GO:0044060 ! regulation of endocrine process is_a: GO:0046883 ! regulation of hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0035929 ! regulates (processual) steroid hormone secretion relationship: RO:0002211 GO:0035929 ! regulates (processual) steroid hormone secretion creation_date: 2011-07-26T08:38:46Z [Term] id: GO:2000832 name: negative regulation of steroid hormone secretion namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of steroid hormone secretion." [GOC:sl] is_a: GO:0032369 ! negative regulation of lipid transport is_a: GO:0046888 ! negative regulation of hormone secretion is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:2000831 ! regulation of steroid hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0035929 ! negatively regulates steroid hormone secretion relationship: RO:0002212 GO:0035929 ! negatively regulates steroid hormone secretion creation_date: 2011-07-26T08:38:50Z [Term] id: GO:2000833 name: positive regulation of steroid hormone secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of steroid hormone secretion." [GOC:sl] is_a: GO:0032370 ! positive regulation of lipid transport is_a: GO:0046887 ! positive regulation of hormone secretion is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:2000831 ! regulation of steroid hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0035929 ! positively regulates steroid hormone secretion relationship: RO:0002213 GO:0035929 ! positively regulates steroid hormone secretion creation_date: 2011-07-26T08:38:51Z [Term] id: GO:2000834 name: regulation of androgen secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of androgen secretion." [GOC:sl] is_a: GO:2000831 ! regulation of steroid hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0035935 ! regulates (processual) androgen secretion relationship: RO:0002211 GO:0035935 ! regulates (processual) androgen secretion creation_date: 2011-07-26T08:39:45Z [Term] id: GO:2000835 name: negative regulation of androgen secretion namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of androgen secretion." [GOC:sl] is_a: GO:2000832 ! negative regulation of steroid hormone secretion is_a: GO:2000834 ! regulation of androgen secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0035935 ! negatively regulates androgen secretion relationship: RO:0002212 GO:0035935 ! negatively regulates androgen secretion creation_date: 2011-07-26T08:39:48Z [Term] id: GO:2000836 name: positive regulation of androgen secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of androgen secretion." [GOC:sl] is_a: GO:2000833 ! positive regulation of steroid hormone secretion is_a: GO:2000834 ! regulation of androgen secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0035935 ! positively regulates androgen secretion relationship: RO:0002213 GO:0035935 ! positively regulates androgen secretion creation_date: 2011-07-26T08:39:51Z [Term] id: GO:2001012 name: mesenchymal cell differentiation involved in renal system development namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the renal system as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10, GOC:obol, GOC:yaf] is_a: GO:0048762 ! mesenchymal cell differentiation intersection_of: GO:0048762 ! mesenchymal cell differentiation intersection_of: BFO:0000050 GO:0072001 ! part of renal system development relationship: BFO:0000050 GO:0072001 ! part of renal system development creation_date: 2011-08-09T04:05:14Z [Term] id: GO:2001013 name: epithelial cell proliferation involved in renal tubule morphogenesis namespace: biological_process def: "Any epithelial cell proliferation that is involved in renal tubule morphogenesis." [GOC:obol] is_a: GO:0050673 ! epithelial cell proliferation intersection_of: GO:0050673 ! epithelial cell proliferation intersection_of: BFO:0000050 GO:0061333 ! part of renal tubule morphogenesis relationship: BFO:0000050 GO:0061333 ! part of renal tubule morphogenesis creation_date: 2011-08-12T11:37:29Z [Term] id: GO:2001014 name: regulation of skeletal muscle cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of skeletal muscle cell differentiation." [GOC:obol] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0035914 ! regulates (processual) skeletal muscle cell differentiation relationship: RO:0002211 GO:0035914 ! regulates (processual) skeletal muscle cell differentiation creation_date: 2011-08-11T08:54:37Z [Term] id: GO:2001015 name: negative regulation of skeletal muscle cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle cell differentiation." [GOC:obol] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:2001014 ! regulation of skeletal muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0035914 ! negatively regulates skeletal muscle cell differentiation relationship: RO:0002212 GO:0035914 ! negatively regulates skeletal muscle cell differentiation creation_date: 2011-08-11T08:54:41Z [Term] id: GO:2001016 name: positive regulation of skeletal muscle cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of skeletal muscle cell differentiation." [GOC:obol] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:2001014 ! regulation of skeletal muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0035914 ! positively regulates skeletal muscle cell differentiation relationship: RO:0002213 GO:0035914 ! positively regulates skeletal muscle cell differentiation creation_date: 2011-08-11T08:54:44Z [Term] id: GO:2001053 name: regulation of mesenchymal cell apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mesenchymal cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0097152 ! regulates (processual) mesenchymal cell apoptotic process relationship: RO:0002211 GO:0097152 ! regulates (processual) mesenchymal cell apoptotic process creation_date: 2011-09-08T02:49:59Z [Term] id: GO:2001054 name: negative regulation of mesenchymal cell apoptotic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] is_a: GO:0043066 ! negative regulation of apoptotic process is_a: GO:2001053 ! regulation of mesenchymal cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0097152 ! negatively regulates mesenchymal cell apoptotic process relationship: RO:0002212 GO:0097152 ! negatively regulates mesenchymal cell apoptotic process creation_date: 2011-09-08T02:50:05Z [Term] id: GO:2001055 name: positive regulation of mesenchymal cell apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] is_a: GO:0043065 ! positive regulation of apoptotic process is_a: GO:2001053 ! regulation of mesenchymal cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0097152 ! positively regulates mesenchymal cell apoptotic process relationship: RO:0002213 GO:0097152 ! positively regulates mesenchymal cell apoptotic process creation_date: 2011-09-08T02:50:09Z [Term] id: GO:2001141 name: regulation of RNA biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of RNA biosynthetic process." [GOC:dph] synonym: "regulation of RNA anabolism" EXACT [GOC:obol] synonym: "regulation of RNA biosynthesis" EXACT [GOC:obol] synonym: "regulation of RNA formation" EXACT [GOC:obol] synonym: "regulation of RNA synthesis" EXACT [GOC:obol] is_a: GO:0010556 ! regulation of macromolecule biosynthetic process is_a: GO:0051252 ! regulation of RNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0032774 ! regulates (processual) RNA biosynthetic process relationship: RO:0002211 GO:0032774 ! regulates (processual) RNA biosynthetic process creation_date: 2011-10-17T11:36:25Z [Term] id: GO:2001198 name: regulation of dendritic cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of dendritic cell differentiation." [GOC:obol] is_a: GO:1902105 ! regulation of leukocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0097028 ! regulates (processual) dendritic cell differentiation relationship: RO:0002211 GO:0097028 ! regulates (processual) dendritic cell differentiation creation_date: 2011-11-04T02:01:27Z [Term] id: GO:2001199 name: negative regulation of dendritic cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell differentiation." [GOC:obol] is_a: GO:1902106 ! negative regulation of leukocyte differentiation is_a: GO:2001198 ! regulation of dendritic cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0097028 ! negatively regulates dendritic cell differentiation relationship: RO:0002212 GO:0097028 ! negatively regulates dendritic cell differentiation creation_date: 2011-11-04T02:01:33Z [Term] id: GO:2001200 name: positive regulation of dendritic cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of dendritic cell differentiation." [GOC:obol] is_a: GO:1902107 ! positive regulation of leukocyte differentiation is_a: GO:2001198 ! regulation of dendritic cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0097028 ! positively regulates dendritic cell differentiation relationship: RO:0002213 GO:0097028 ! positively regulates dendritic cell differentiation creation_date: 2011-11-04T02:01:36Z [Term] id: GO:2001212 name: regulation of vasculogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of vasculogenesis." [GOC:obol] synonym: "regulation of vascular morphogenesis" EXACT [GOC:obol] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001570 ! regulates (processual) vasculogenesis relationship: RO:0002211 GO:0001570 ! regulates (processual) vasculogenesis creation_date: 2011-11-15T01:22:31Z [Term] id: GO:2001213 name: negative regulation of vasculogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of vasculogenesis." [GOC:obol] synonym: "negative regulation of vascular morphogenesis" EXACT [GOC:obol] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:2001212 ! regulation of vasculogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001570 ! negatively regulates vasculogenesis relationship: RO:0002212 GO:0001570 ! negatively regulates vasculogenesis creation_date: 2011-11-15T01:22:36Z [Term] id: GO:2001214 name: positive regulation of vasculogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of vasculogenesis." [GOC:obol] synonym: "positive regulation of vascular morphogenesis" EXACT [GOC:obol] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:2001212 ! regulation of vasculogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001570 ! positively regulates vasculogenesis relationship: RO:0002213 GO:0001570 ! positively regulates vasculogenesis creation_date: 2011-11-15T01:22:39Z [Term] id: GO:2001222 name: regulation of neuron migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of neuron migration." [GOC:obol] synonym: "regulation of neuron chemotaxis" EXACT [GOC:obol] synonym: "regulation of neuronal migration" EXACT [GOC:obol] is_a: GO:0030334 ! regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001764 ! regulates (processual) neuron migration relationship: RO:0002160 NCBITaxon:33208 ! only in taxon Metazoa relationship: RO:0002162 NCBITaxon:33208 {all_only="true"} ! in taxon Metazoa relationship: RO:0002211 GO:0001764 ! regulates (processual) neuron migration creation_date: 2011-11-17T10:01:38Z [Term] id: GO:2001223 name: negative regulation of neuron migration namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of neuron migration." [GOC:obol] synonym: "negative regulation of neuron chemotaxis" EXACT [GOC:obol] synonym: "negative regulation of neuronal migration" EXACT [GOC:obol] is_a: GO:0030336 ! negative regulation of cell migration is_a: GO:2001222 ! regulation of neuron migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001764 ! negatively regulates neuron migration relationship: RO:0002212 GO:0001764 ! negatively regulates neuron migration creation_date: 2011-11-17T10:01:45Z [Term] id: GO:2001224 name: positive regulation of neuron migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of neuron migration." [GOC:obol] synonym: "positive regulation of neuron chemotaxis" EXACT [GOC:obol] synonym: "positive regulation of neuronal migration" EXACT [GOC:obol] is_a: GO:0030335 ! positive regulation of cell migration is_a: GO:2001222 ! regulation of neuron migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001764 ! positively regulates neuron migration relationship: RO:0002213 GO:0001764 ! positively regulates neuron migration creation_date: 2011-11-17T10:01:49Z [Term] id: GO:2001233 name: regulation of apoptotic signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate or extent of apoptotic signaling pathway." [GOC:mtg_apoptosis] synonym: "regulation of apoptotic signalling pathway" EXACT [GOC:mah] is_a: GO:0009966 ! regulation of signal transduction is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0097190 ! regulates (processual) apoptotic signaling pathway relationship: RO:0002211 GO:0097190 ! regulates (processual) apoptotic signaling pathway creation_date: 2011-11-24T01:20:49Z [Term] id: GO:2001234 name: negative regulation of apoptotic signaling pathway namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic signaling pathway." [GOC:mtg_apoptosis] synonym: "negative regulation of apoptotic signalling pathway" EXACT [GOC:mah] is_a: GO:0009968 ! negative regulation of signal transduction is_a: GO:0043066 ! negative regulation of apoptotic process is_a: GO:2001233 ! regulation of apoptotic signaling pathway intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0097190 ! negatively regulates apoptotic signaling pathway relationship: RO:0002212 GO:0097190 ! negatively regulates apoptotic signaling pathway creation_date: 2011-11-24T01:20:54Z [Term] id: GO:2001235 name: positive regulation of apoptotic signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of apoptotic signaling pathway." [GOC:mtg_apoptosis] synonym: "positive regulation of apoptotic signalling pathway" EXACT [GOC:mah] is_a: GO:0009967 ! positive regulation of signal transduction is_a: GO:0043065 ! positive regulation of apoptotic process is_a: GO:2001233 ! regulation of apoptotic signaling pathway intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0097190 ! positively regulates apoptotic signaling pathway relationship: RO:0002213 GO:0097190 ! positively regulates apoptotic signaling pathway creation_date: 2011-11-24T01:20:58Z [Term] id: GO:2001251 name: negative regulation of chromosome organization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of chromosome organization." [GOC:obol] synonym: "negative regulation of chromosome organisation" EXACT [GOC:obol] is_a: GO:0010639 ! negative regulation of organelle organization is_a: GO:0033044 ! regulation of chromosome organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0051276 ! negatively regulates chromosome organization relationship: RO:0002212 GO:0051276 ! negatively regulates chromosome organization creation_date: 2011-12-02T02:01:20Z [Term] id: GO:2001252 name: positive regulation of chromosome organization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of chromosome organization." [GOC:obol] synonym: "positive regulation of chromosome organisation" EXACT [GOC:obol] is_a: GO:0010638 ! positive regulation of organelle organization is_a: GO:0033044 ! regulation of chromosome organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0051276 ! positively regulates chromosome organization relationship: RO:0002213 GO:0051276 ! positively regulates chromosome organization creation_date: 2011-12-02T02:01:26Z [Term] id: IAO:0000027 name: data item def: "An information content entity that is intended to be a truthful statement about something (modulo, e.g., measurement precision or other systematic errors) and is constructed/acquired by a method which reliably tends to produce (approximately) truthful statements." [] is_a: IAO:0000030 ! information content entity property_value: IAO:0000118 "data" xsd:string [Term] id: IAO:0000028 name: symbol def: "An information content entity that is a mark(s) or character(s) used as a conventional representation of another entity." [] is_a: IAO:0000030 ! information content entity [Term] id: IAO:0000030 name: information content entity def: "A generically dependent continuant that is about some thing." [] is_a: BFO:0000031 ! generically dependent continuant relationship: IAO:0000136 BFO:0000001 ! is about entity [Term] id: IAO:0000078 name: curation status specification def: "The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value." [] is_a: IAO:0000102 ! data about an ontology part [Term] id: IAO:0000102 name: data about an ontology part def: "Data about an ontology part is a data item about a part of an ontology, for example a term" [] is_a: IAO:0000027 ! data item [Term] id: IAO:0000225 name: obsolescence reason specification def: "The reason for which a term has been deprecated. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value." [] is_a: IAO:0000102 ! data about an ontology part [Term] id: IAO:0000409 name: denotator type def: "A denotator type indicates how a term should be interpreted from an ontological perspective." [] is_a: IAO:0000102 ! data about an ontology part [Term] id: IAO:0000577 name: centrally registered identifier symbol def: "A symbol that is part of a CRID and that is sufficient to look up a record from the CRID's registry." [] is_a: IAO:0000028 ! symbol relationship: BFO:0000050 IAO:0000578 ! part of centrally registered identifier property_value: IAO:0000118 "CRID symbol" xsd:string [Term] id: IAO:0000578 name: centrally registered identifier def: "An information content entity that consists of a CRID symbol and additional information about the CRID registry to which it belongs." [] is_a: IAO:0020000 ! identifier relationship: BFO:0000051 IAO:0000577 ! has part centrally registered identifier symbol property_value: IAO:0000118 "CRID" xsd:string [Term] id: IAO:0000579 name: centrally registered identifier registry def: "A code set of CRID records, each consisting of a CRID symbol and additional information which was recorded in the code set through an assigning a centrally registered identifier process." [] is_a: IAO:0020020 ! code set property_value: IAO:0000118 "CRID registry" xsd:string [Term] id: IAO:0020000 name: identifier def: "An information content entity that is the outcome of a dubbing process and is used to refer to one instance of entity shared by a group of people to refer to that individual entity." [] is_a: IAO:0000030 ! information content entity intersection_of: IAO:0000030 ! information content entity intersection_of: IAO:0000219 BFO:0000001 ! denotes entity intersection_of: OBI:0000312 IAO:0020010 ! is_specified_output_of identifier creating process relationship: IAO:0000219 BFO:0000001 ! denotes entity relationship: OBI:0000312 IAO:0020010 ! is_specified_output_of identifier creating process property_value: IAO:0000118 "proper name" xsd:string property_value: x_1.1:creator "Mathias Brochhausen" xsd:string [Term] id: IAO:0020010 name: identifier creating process def: "A planned process that provides a reference to an individual entity shared by a group of subscribers to refer to that individual entity." [] is_a: OBI:0000011 ! planned process intersection_of: OBI:0000011 ! planned process intersection_of: OBI:0000299 IAO:0020000 ! has_specified_output identifier relationship: OBI:0000299 IAO:0020000 ! has_specified_output identifier property_value: IAO:0000118 "dubbing process" xsd:string property_value: IAO:0000118 "naming" xsd:string property_value: x_1.1:creator "Mathias Brochhausen" xsd:string [Term] id: IAO:0020020 name: code set def: "An information content entity that is a collection of other information content entities that has been created to identify or annotate things in a specified domain, and where the intention of its creators is that the collection has a one-to-one correspondence with those things." [] is_a: IAO:0000030 ! information content entity relationship: BFO:0000051 IAO:0020000 ! has part identifier property_value: IAO:0000118 "code map" xsd:string property_value: IAO:0000118 "code system" xsd:string property_value: IAO:0000118 "codeset" xsd:string property_value: IAO:0000118 "coding system" xsd:string property_value: IAO:0000118 "controlled vocabulary" xsd:string property_value: x_1.1:contributor "Alan Ruttenberg" xsd:string property_value: x_1.1:contributor "Clint Dowland" xsd:string property_value: x_1.1:contributor "Matt Diller" xsd:string property_value: x_1.1:contributor "Sarah Bost" xsd:string property_value: x_1.1:contributor "William R. Hogan" xsd:string [Term] id: NBO:0000001 name: body part movement namespace: behavior_ontology def: "A change of place or position of part of an organism that does not involve the entire organism [NBO:SMAC]" [] synonym: "stationary movement" EXACT [] is_a: NBO:0000338 ! kinesthetic behavior property_value: x_1.1:date "2011-04-14T01:03:39Z" xsd:string [Term] id: NBO:0000007 name: mouth movement namespace: behavior_ontology def: "The act of moving any of the tissues and hard structures surrounding the mouth other than teeth, jaws or filter structures [NBO:AC]" [] is_a: NBO:0000001 ! body part movement property_value: x_1.1:date "2011-04-14T01:03:39Z" xsd:string [Term] id: NBO:0000073 name: chewing namespace: behavior_ontology def: "The act of repeated grinding, tearing, and or crushing with teeth or jaws [NBO:SMAC]" [] synonym: "chew" EXACT [] synonym: "gnaw" EXACT [] synonym: "mastication" EXACT [] is_a: NBO:0000747 ! jaw movement property_value: x_1.1:date "2011-04-14T01:20:02Z" xsd:string [Term] id: NBO:0000313 name: behavior process namespace: behavior_ontology def: "\"The action, reaction, or performance of an organism in response to external or internal stimuli.\" [GO:GO\\:0007610]" [] synonym: "behavior" EXACT [] synonym: "behaviour" EXACT [] is_a: GO:0007610 ! behavior property_value: x_1.1:date "2011-04-05T09:53:10Z" xsd:string [Term] id: NBO:0000338 name: kinesthetic behavior namespace: behavior_ontology def: "\"Movement behavior of the body or its parts.\"" [] is_a: NBO:0000313 ! behavior process property_value: x_1.1:date "2011-04-05T02:08:47Z" xsd:string [Term] id: NBO:0000747 name: jaw movement namespace: behavior_ontology is_a: NBO:0000007 ! mouth movement property_value: x_1.1:date "2012-03-17T09:51:17Z" xsd:string [Term] id: NBO:0001786 name: regulation of behavior def: "\"Any process that modulates the frequency, rate or extent of behavior, the specific actions or reactions of an organism in response to external or internal stimuli.\" [GO:0050795]" [] is_a: NBO:0000313 ! behavior process relationship: RO:0002211 NBO:0000313 ! regulates (processual) behavior process [Term] id: NCBITaxon:1 name: root namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:30365038 xref: PMID:32761142 [Term] id: NCBITaxon:10066 name: Muridae namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:15371245 is_a: NCBITaxon:337687 ! Muroidea [Term] id: NCBITaxon:10088 name: Mus namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:39107 ! Murinae disjoint_from: NCBITaxon:10114 ! Rattus [Term] id: NCBITaxon:10090 name: Mus musculus namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:862507 ! Mus [Term] id: NCBITaxon:10114 name: Rattus namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:39107 ! Murinae [Term] id: NCBITaxon:105389 name: Sedentaria namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:6341 ! Polychaeta [Term] id: NCBITaxon:105391 name: Canalipalpata namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:105389 ! Sedentaria [Term] id: NCBITaxon:110814 name: Xenoturbellida namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:1312402 ! Xenacoelomorpha disjoint_from: NCBITaxon:147099 ! Acoelomorpha [Term] id: NCBITaxon:110815 name: Xenoturbella namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:1547233 ! Xenoturbellidae [Term] id: NCBITaxon:117565 name: Myxini namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:1476529 ! Cyclostomata [Term] id: NCBITaxon:117570 name: Teleostomi namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:7776 ! Gnathostomata disjoint_from: NCBITaxon:7777 ! Chondrichthyes [Term] id: NCBITaxon:117571 name: Euteleostomi namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:117570 ! Teleostomi [Term] id: NCBITaxon:119089 name: Chromadorea namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:6231 ! Nematoda [Term] id: NCBITaxon:1206794 name: Ecdysozoa namespace: ncbi_taxonomy namespace: protein xref: GC_ID:1 is_a: NCBITaxon:33317 ! Protostomia disjoint_from: NCBITaxon:2697495 ! Spiralia [Term] id: NCBITaxon:1206795 name: Lophotrochozoa namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:2697495 ! Spiralia [Term] id: NCBITaxon:123365 name: Neoteleostei namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:1489388 ! Euteleosteomorpha [Term] id: NCBITaxon:123366 name: Eurypterygia namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:123365 ! Neoteleostei [Term] id: NCBITaxon:123367 name: Ctenosquamata namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:123366 ! Eurypterygia [Term] id: NCBITaxon:123368 name: Acanthomorphata namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:123367 ! Ctenosquamata [Term] id: NCBITaxon:123369 name: Euacanthomorphacea namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:123368 ! Acanthomorphata [Term] id: NCBITaxon:124129 name: Acipenserinae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:7900 ! Acipenseridae [Term] id: NCBITaxon:124130 name: Acipenserini namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:124129 ! Acipenserinae [Term] id: NCBITaxon:131209 name: Zygnemophyceae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:131221 ! Streptophytina disjoint_from: NCBITaxon:3193 ! Embryophyta [Term] id: NCBITaxon:131221 name: Streptophytina namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:35493 ! Streptophyta [Term] id: NCBITaxon:1312402 name: Xenacoelomorpha namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:33213 ! Bilateria disjoint_from: NCBITaxon:33317 ! Protostomia disjoint_from: NCBITaxon:33511 ! Deuterostomia [Term] id: NCBITaxon:131567 name: cellular organisms namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:1 ! root [Term] id: NCBITaxon:1329799 name: Archelosauria namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:22839753 xref: PMID:25450099 is_a: NCBITaxon:32561 ! Sauria [Term] id: NCBITaxon:1338369 name: Dipnotetrapodomorpha namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:8287 ! Sarcopterygii [Term] id: NCBITaxon:142796 name: Eumycetozoa namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:11062127 xref: PMID:9342353 is_a: NCBITaxon:2605435 ! Evosea [Term] id: NCBITaxon:1437010 name: Boreoeutheria namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:11743200 xref: PMID:11791233 is_a: NCBITaxon:9347 ! Eutheria [Term] id: NCBITaxon:1437180 name: Acrogymnospermae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:58024 ! Spermatophyta disjoint_from: NCBITaxon:3398 ! Magnoliopsida [Term] id: NCBITaxon:1445966 name: Gnetidae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:3372 ! Gnetopsida [Term] id: NCBITaxon:147099 name: Acoelomorpha namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:1312402 ! Xenacoelomorpha [Term] id: NCBITaxon:147537 name: Saccharomycotina namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:716545 ! saccharomyceta [Term] id: NCBITaxon:147554 name: Schizosaccharomycetes namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:451866 ! Taphrinomycotina [Term] id: NCBITaxon:1476529 name: Cyclostomata namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:7742 ! Vertebrata disjoint_from: NCBITaxon:7776 ! Gnathostomata [Term] id: NCBITaxon:1489341 name: Osteoglossocephalai namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:32443 ! Teleostei [Term] id: NCBITaxon:1489388 name: Euteleosteomorpha namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:186625 ! Clupeocephala disjoint_from: NCBITaxon:186634 ! Otomorpha [Term] id: NCBITaxon:1489872 name: Percomorphaceae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:123369 ! Euacanthomorphacea [Term] id: NCBITaxon:1489922 name: Eupercaria namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:1489872 ! Percomorphaceae [Term] id: NCBITaxon:1547233 name: Xenoturbellidae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:110814 ! Xenoturbellida [Term] id: NCBITaxon:186622 name: Acipenseroidei namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:7899 ! Acipenseriformes [Term] id: NCBITaxon:186623 name: Actinopteri namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:7898 ! Actinopterygii [Term] id: NCBITaxon:186625 name: Clupeocephala namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:1489341 ! Osteoglossocephalai [Term] id: NCBITaxon:186626 name: Otophysi namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:32519 ! Ostariophysi [Term] id: NCBITaxon:186627 name: Cypriniphysae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:186626 ! Otophysi [Term] id: NCBITaxon:186634 name: Otomorpha namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:186625 ! Clupeocephala [Term] id: NCBITaxon:1963758 name: Myomorpha namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:9989 ! Rodentia [Term] id: NCBITaxon:197562 name: Pancrustacea namespace: ncbi_taxonomy namespace: protein xref: GC_ID:1 xref: PMID:10874751 xref: PMID:11557979 is_a: NCBITaxon:197563 ! Mandibulata [Term] id: NCBITaxon:197563 name: Mandibulata namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:11557979 xref: PMID:9727836 is_a: NCBITaxon:6656 ! Arthropoda [Term] id: NCBITaxon:2 name: Bacteria namespace: ncbi_taxonomy xref: GC_ID:11 xref: PMID:10425795 xref: PMID:10425796 xref: PMID:10425797 xref: PMID:10490293 xref: PMID:10843050 xref: PMID:10939651 xref: PMID:10939673 xref: PMID:10939677 xref: PMID:11211268 xref: PMID:11321083 xref: PMID:11321113 xref: PMID:11411719 xref: PMID:11540071 xref: PMID:11542017 xref: PMID:11542087 xref: PMID:11760965 xref: PMID:12054223 xref: PMID:2112744 xref: PMID:270744 xref: PMID:32628106 xref: PMID:36748408 xref: PMID:7520741 xref: PMID:8123559 xref: PMID:8186100 xref: PMID:8590690 xref: PMID:9103655 xref: PMID:9336922 is_a: NCBITaxon:131567 ! cellular organisms disjoint_from: NCBITaxon:2157 ! Archaea disjoint_from: NCBITaxon:2759 ! Eukaryota [Term] id: NCBITaxon:2058185 name: Dictyosteliaceae namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:29367151 is_a: NCBITaxon:2058949 ! Dictyosteliales [Term] id: NCBITaxon:2058949 name: Dictyosteliales namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:29367151 is_a: NCBITaxon:33083 ! Dictyostelia [Term] id: NCBITaxon:207598 name: Homininae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:9604 ! Hominidae [Term] id: NCBITaxon:2157 name: Archaea namespace: ncbi_taxonomy xref: GC_ID:11 xref: PMID:10425795 xref: PMID:10425796 xref: PMID:10425797 xref: PMID:10490293 xref: PMID:10843050 xref: PMID:10939651 xref: PMID:10939673 xref: PMID:10939677 xref: PMID:11211268 xref: PMID:11321083 xref: PMID:11321113 xref: PMID:11411719 xref: PMID:11540071 xref: PMID:11541975 xref: PMID:11542064 xref: PMID:11542149 xref: PMID:11760965 xref: PMID:12054223 xref: PMID:2112744 xref: PMID:25527841 xref: PMID:270744 xref: PMID:32628106 xref: PMID:36748408 xref: PMID:8123559 xref: PMID:8590690 xref: PMID:9103655 xref: PMID:9336922 is_a: NCBITaxon:131567 ! cellular organisms disjoint_from: NCBITaxon:2759 ! Eukaryota [Term] id: NCBITaxon:2301116 name: Rhabditina namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:6236 ! Rhabditida [Term] id: NCBITaxon:2301119 name: Rhabditomorpha namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:2301116 ! Rhabditina [Term] id: NCBITaxon:2605435 name: Evosea namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:554915 ! Amoebozoa [Term] id: NCBITaxon:2611352 name: Discoba namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:2759 ! Eukaryota disjoint_from: NCBITaxon:2698737 ! Sar disjoint_from: NCBITaxon:33090 ! Viridiplantae disjoint_from: NCBITaxon:33154 ! Opisthokonta disjoint_from: NCBITaxon:38254 ! Glaucocystophyceae disjoint_from: NCBITaxon:554915 ! Amoebozoa [Term] id: NCBITaxon:262014 name: Xenopus namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:8353 ! Xenopus [Term] id: NCBITaxon:2684882 name: Zygnematophycidae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:131209 ! Zygnemophyceae [Term] id: NCBITaxon:2697495 name: Spiralia namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:33317 ! Protostomia [Term] id: NCBITaxon:2698737 name: Sar namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:2759 ! Eukaryota disjoint_from: NCBITaxon:33090 ! Viridiplantae disjoint_from: NCBITaxon:33154 ! Opisthokonta disjoint_from: NCBITaxon:38254 ! Glaucocystophyceae disjoint_from: NCBITaxon:554915 ! Amoebozoa [Term] id: NCBITaxon:2743709 name: Danionidae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:30727 ! Cyprinoidei [Term] id: NCBITaxon:2743711 name: Danioninae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:2743709 ! Danionidae [Term] id: NCBITaxon:2759 name: Eukaryota namespace: ncbi_taxonomy namespace: protein xref: GC_ID:1 xref: PMID:23020233 xref: PMID:30257078 is_a: COB:0000022 ! organism is_a: NCBITaxon:131567 ! cellular organisms [Term] id: NCBITaxon:30319 name: Pipoidea namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:8342 ! Anura [Term] id: NCBITaxon:30727 name: Cyprinoidei namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:7952 ! Cypriniformes [Term] id: NCBITaxon:31022 name: Tetraodontiformes namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:1489922 ! Eupercaria [Term] id: NCBITaxon:31028 name: Tetraodontoidei namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:31022 ! Tetraodontiformes [Term] id: NCBITaxon:31031 name: Tetraodontidae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:32517 ! Tetradontoidea [Term] id: NCBITaxon:31032 name: Takifugu namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:31031 ! Tetraodontidae [Term] id: NCBITaxon:31033 name: Takifugu rubripes namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:31032 ! Takifugu [Term] id: NCBITaxon:314146 name: Euarchontoglires namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:11214319 xref: PMID:12082125 xref: PMID:12878460 xref: PMID:15522813 is_a: NCBITaxon:1437010 ! Boreoeutheria [Term] id: NCBITaxon:314147 name: Glires namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:11214319 xref: PMID:12082125 xref: PMID:15522813 is_a: NCBITaxon:314146 ! Euarchontoglires disjoint_from: NCBITaxon:9443 ! Primates [Term] id: NCBITaxon:314293 name: Simiiformes namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:376913 ! Haplorrhini [Term] id: NCBITaxon:314295 name: Hominoidea namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:9526 ! Catarrhini [Term] id: NCBITaxon:3176 name: Zygnematales namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:2684882 ! Zygnematophycidae [Term] id: NCBITaxon:3193 name: Embryophyta namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:131221 ! Streptophytina [Term] id: NCBITaxon:32341 name: Sophophora namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:7215 ! Drosophila [Term] id: NCBITaxon:32346 name: melanogaster group namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:32341 ! Sophophora [Term] id: NCBITaxon:32351 name: melanogaster subgroup namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:32346 ! melanogaster group [Term] id: NCBITaxon:32440 name: Chondrostei namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:186623 ! Actinopteri disjoint_from: NCBITaxon:41665 ! Neopterygii [Term] id: NCBITaxon:32443 name: Teleostei namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:41665 ! Neopterygii [Term] id: NCBITaxon:32517 name: Tetradontoidea namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:31028 ! Tetraodontoidei [Term] id: NCBITaxon:32519 name: Ostariophysi namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:186634 ! Otomorpha [Term] id: NCBITaxon:32523 name: Tetrapoda namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:1338369 ! Dipnotetrapodomorpha disjoint_from: NCBITaxon:7878 ! Dipnomorpha [Term] id: NCBITaxon:32524 name: Amniota namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:32523 ! Tetrapoda disjoint_from: NCBITaxon:8292 ! Amphibia [Term] id: NCBITaxon:32525 name: Theria namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:40674 ! Mammalia disjoint_from: NCBITaxon:9254 ! Prototheria [Term] id: NCBITaxon:32561 name: Sauria namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:8457 ! Sauropsida [Term] id: NCBITaxon:33083 name: Dictyostelia namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:11062127 xref: PMID:29367151 xref: PMID:9342353 is_a: NCBITaxon:142796 ! Eumycetozoa [Term] id: NCBITaxon:33090 name: Viridiplantae namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:16248873 xref: PMID:30257078 is_a: NCBITaxon:2759 ! Eukaryota disjoint_from: NCBITaxon:33154 ! Opisthokonta disjoint_from: NCBITaxon:38254 ! Glaucocystophyceae disjoint_from: NCBITaxon:554915 ! Amoebozoa [Term] id: NCBITaxon:3312 name: Coniferophyta namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:1437180 ! Acrogymnospermae disjoint_from: NCBITaxon:3372 ! Gnetopsida [Term] id: NCBITaxon:33154 name: Opisthokonta namespace: ncbi_taxonomy namespace: protein xref: GC_ID:1 is_a: NCBITaxon:2759 ! Eukaryota disjoint_from: NCBITaxon:38254 ! Glaucocystophyceae disjoint_from: NCBITaxon:554915 ! Amoebozoa [Term] id: NCBITaxon:33208 name: Metazoa namespace: ncbi_taxonomy namespace: protein xref: GC_ID:1 is_a: NCBITaxon:33154 ! Opisthokonta disjoint_from: NCBITaxon:4751 ! Fungi [Term] id: NCBITaxon:33213 name: Bilateria namespace: ncbi_taxonomy namespace: protein xref: GC_ID:1 is_a: NCBITaxon:6072 ! Eumetazoa disjoint_from: NCBITaxon:6073 ! Cnidaria [Term] id: NCBITaxon:33317 name: Protostomia namespace: ncbi_taxonomy namespace: protein xref: GC_ID:1 is_a: NCBITaxon:33213 ! Bilateria disjoint_from: NCBITaxon:33511 ! Deuterostomia [Term] id: NCBITaxon:33340 name: Neoptera namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:7496 ! Pterygota [Term] id: NCBITaxon:33392 name: Endopterygota namespace: ncbi_taxonomy namespace: protein xref: GC_ID:1 is_a: NCBITaxon:33340 ! Neoptera [Term] id: NCBITaxon:33511 name: Deuterostomia namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:33213 ! Bilateria [Term] id: NCBITaxon:33630 name: Alveolata namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:2698737 ! Sar [Term] id: NCBITaxon:33682 name: Euglenozoa namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:2611352 ! Discoba [Term] id: NCBITaxon:3372 name: Gnetopsida namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:1437180 ! Acrogymnospermae [Term] id: NCBITaxon:337687 name: Muroidea namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:15019624 xref: PMID:15371245 is_a: NCBITaxon:1963758 ! Myomorpha [Term] id: NCBITaxon:3378 name: Gnetales namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:1445966 ! Gnetidae [Term] id: NCBITaxon:3398 name: Magnoliopsida namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:25249442 is_a: NCBITaxon:58024 ! Spermatophyta [Term] id: NCBITaxon:34346 name: Schizosaccharomycetales namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:147554 ! Schizosaccharomycetes [Term] id: NCBITaxon:35493 name: Streptophyta namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:33090 ! Viridiplantae [Term] id: NCBITaxon:376913 name: Haplorrhini namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:9443 ! Primates [Term] id: NCBITaxon:38254 name: Glaucocystophyceae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:2759 ! Eukaryota disjoint_from: NCBITaxon:554915 ! Amoebozoa [Term] id: NCBITaxon:39107 name: Murinae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:10066 ! Muridae [Term] id: NCBITaxon:40674 name: Mammalia namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:32524 ! Amniota disjoint_from: NCBITaxon:8457 ! Sauropsida [Term] id: NCBITaxon:41324 name: Siboglinidae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:6362 ! Sabellida [Term] id: NCBITaxon:41665 name: Neopterygii namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:186623 ! Actinopteri [Term] id: NCBITaxon:41666 name: Batrachia namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:8292 ! Amphibia [Term] id: NCBITaxon:436486 name: Dinosauria namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:8492 ! Archosauria [Term] id: NCBITaxon:436489 name: Saurischia namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:436486 ! Dinosauria [Term] id: NCBITaxon:436491 name: Theropoda namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:436489 ! Saurischia [Term] id: NCBITaxon:436492 name: Coelurosauria namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:436491 ! Theropoda [Term] id: NCBITaxon:43733 name: Muscomorpha namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:7203 ! Brachycera [Term] id: NCBITaxon:43738 name: Schizophora namespace: ncbi_taxonomy namespace: protein xref: GC_ID:1 is_a: NCBITaxon:480117 ! Cyclorrhapha [Term] id: NCBITaxon:43741 name: Acalyptratae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:43738 ! Schizophora [Term] id: NCBITaxon:43746 name: Ephydroidea namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:43741 ! Acalyptratae [Term] id: NCBITaxon:43845 name: Drosophilinae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:7214 ! Drosophilidae [Term] id: NCBITaxon:451864 name: Dikarya namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:15689432 xref: PMID:16151185 xref: PMID:17010206 xref: PMID:17051209 xref: PMID:17572334 is_a: NCBITaxon:4751 ! Fungi [Term] id: NCBITaxon:451866 name: Taphrinomycotina namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:4890 ! Ascomycota disjoint_from: NCBITaxon:716545 ! saccharomyceta [Term] id: NCBITaxon:46877 name: Drosophilini namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:43845 ! Drosophilinae [Term] id: NCBITaxon:4751 name: Fungi namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:11062127 xref: PMID:12684019 is_a: NCBITaxon:33154 ! Opisthokonta [Term] id: NCBITaxon:480117 name: Cyclorrhapha namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:480118 ! Eremoneura [Term] id: NCBITaxon:480118 name: Eremoneura namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:43733 ! Muscomorpha [Term] id: NCBITaxon:4890 name: Ascomycota namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:17572334 is_a: NCBITaxon:451864 ! Dikarya [Term] id: NCBITaxon:4891 name: Saccharomycetes namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:147537 ! Saccharomycotina [Term] id: NCBITaxon:4892 name: Saccharomycetales namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:4891 ! Saccharomycetes [Term] id: NCBITaxon:4893 name: Saccharomycetaceae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:4892 ! Saccharomycetales [Term] id: NCBITaxon:4894 name: Schizosaccharomycetaceae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:34346 ! Schizosaccharomycetales [Term] id: NCBITaxon:4895 name: Schizosaccharomyces namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:4894 ! Schizosaccharomycetaceae [Term] id: NCBITaxon:4896 name: Schizosaccharomyces pombe namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:4895 ! Schizosaccharomyces [Term] id: NCBITaxon:4930 name: Saccharomyces namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:4893 ! Saccharomycetaceae [Term] id: NCBITaxon:4932 name: Saccharomyces cerevisiae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:4930 ! Saccharomyces [Term] id: NCBITaxon:50557 name: Insecta namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:6960 ! Hexapoda [Term] id: NCBITaxon:554915 name: Amoebozoa namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:23020233 xref: PMID:30257078 is_a: NCBITaxon:2759 ! Eukaryota [Term] id: NCBITaxon:55879 name: Rhabditoidea namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:2301119 ! Rhabditomorpha [Term] id: NCBITaxon:55885 name: Peloderinae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:6243 ! Rhabditidae [Term] id: NCBITaxon:5782 name: Dictyostelium namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:29367151 is_a: NCBITaxon:2058185 ! Dictyosteliaceae [Term] id: NCBITaxon:58023 name: Tracheophyta namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:3193 ! Embryophyta [Term] id: NCBITaxon:58024 name: Spermatophyta namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:78536 ! Euphyllophyta [Term] id: NCBITaxon:6040 name: Porifera namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:33208 ! Metazoa disjoint_from: NCBITaxon:6072 ! Eumetazoa [Term] id: NCBITaxon:6072 name: Eumetazoa namespace: ncbi_taxonomy namespace: protein xref: GC_ID:1 is_a: NCBITaxon:33208 ! Metazoa [Term] id: NCBITaxon:6073 name: Cnidaria namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:6072 ! Eumetazoa [Term] id: NCBITaxon:6157 name: Platyhelminthes namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:1206795 ! Lophotrochozoa disjoint_from: NCBITaxon:6340 ! Annelida [Term] id: NCBITaxon:6231 name: Nematoda namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:1206794 ! Ecdysozoa disjoint_from: NCBITaxon:88770 ! Panarthropoda [Term] id: NCBITaxon:6236 name: Rhabditida namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:119089 ! Chromadorea [Term] id: NCBITaxon:6237 name: Caenorhabditis namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:55885 ! Peloderinae [Term] id: NCBITaxon:6239 name: Caenorhabditis elegans namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:6237 ! Caenorhabditis [Term] id: NCBITaxon:6243 name: Rhabditidae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:55879 ! Rhabditoidea [Term] id: NCBITaxon:6340 name: Annelida namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:1206795 ! Lophotrochozoa [Term] id: NCBITaxon:6341 name: Polychaeta namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:6340 ! Annelida [Term] id: NCBITaxon:6362 name: Sabellida namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:105391 ! Canalipalpata [Term] id: NCBITaxon:6656 name: Arthropoda namespace: ncbi_taxonomy namespace: protein xref: GC_ID:1 is_a: NCBITaxon:88770 ! Panarthropoda [Term] id: NCBITaxon:6960 name: Hexapoda namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:197562 ! Pancrustacea [Term] id: NCBITaxon:7147 name: Diptera namespace: ncbi_taxonomy namespace: protein xref: GC_ID:1 is_a: NCBITaxon:33392 ! Endopterygota [Term] id: NCBITaxon:716545 name: saccharomyceta namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:4890 ! Ascomycota [Term] id: NCBITaxon:7203 name: Brachycera namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:7147 ! Diptera [Term] id: NCBITaxon:7214 name: Drosophilidae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:43746 ! Ephydroidea [Term] id: NCBITaxon:7215 name: Drosophila namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:46877 ! Drosophilini [Term] id: NCBITaxon:7227 name: Drosophila melanogaster namespace: ncbi_taxonomy namespace: protein xref: GC_ID:1 is_a: NCBITaxon:32351 ! melanogaster subgroup [Term] id: NCBITaxon:7496 name: Pterygota namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:85512 ! Dicondylia [Term] id: NCBITaxon:7711 name: Chordata namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:33511 ! Deuterostomia [Term] id: NCBITaxon:7712 name: Tunicata namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:7711 ! Chordata disjoint_from: NCBITaxon:89593 ! Craniata [Term] id: NCBITaxon:7742 name: Vertebrata namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:89593 ! Craniata [Term] id: NCBITaxon:7761 name: Myxiniformes namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:117565 ! Myxini [Term] id: NCBITaxon:7762 name: Myxinidae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:7761 ! Myxiniformes [Term] id: NCBITaxon:7776 name: Gnathostomata namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:7742 ! Vertebrata [Term] id: NCBITaxon:7777 name: Chondrichthyes namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:7776 ! Gnathostomata [Term] id: NCBITaxon:78536 name: Euphyllophyta namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:58023 ! Tracheophyta [Term] id: NCBITaxon:7863 name: Holocephali namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:7777 ! Chondrichthyes [Term] id: NCBITaxon:7864 name: Chimaeriformes namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:7863 ! Holocephali [Term] id: NCBITaxon:7878 name: Dipnomorpha namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:1338369 ! Dipnotetrapodomorpha [Term] id: NCBITaxon:7898 name: Actinopterygii namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:117571 ! Euteleostomi disjoint_from: NCBITaxon:8287 ! Sarcopterygii [Term] id: NCBITaxon:7899 name: Acipenseriformes namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:32440 ! Chondrostei [Term] id: NCBITaxon:7900 name: Acipenseridae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:186622 ! Acipenseroidei [Term] id: NCBITaxon:7901 name: Acipenser namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:124130 ! Acipenserini [Term] id: NCBITaxon:7952 name: Cypriniformes namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:186627 ! Cypriniphysae [Term] id: NCBITaxon:7954 name: Danio namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:2743711 ! Danioninae [Term] id: NCBITaxon:7955 name: Danio rerio namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:7954 ! Danio [Term] id: NCBITaxon:8287 name: Sarcopterygii namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:117571 ! Euteleostomi [Term] id: NCBITaxon:8292 name: Amphibia namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:32523 ! Tetrapoda [Term] id: NCBITaxon:8342 name: Anura namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:41666 ! Batrachia [Term] id: NCBITaxon:8352 name: Pipidae namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:2385174 is_a: NCBITaxon:30319 ! Pipoidea [Term] id: NCBITaxon:8353 name: Xenopus namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:2385174 is_a: NCBITaxon:8360 ! Xenopodinae [Term] id: NCBITaxon:8355 name: Xenopus laevis namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:262014 ! Xenopus [Term] id: NCBITaxon:8360 name: Xenopodinae namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:2385174 is_a: NCBITaxon:8352 ! Pipidae [Term] id: NCBITaxon:8457 name: Sauropsida namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:32524 ! Amniota [Term] id: NCBITaxon:8492 name: Archosauria namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:1329799 ! Archelosauria [Term] id: NCBITaxon:85512 name: Dicondylia namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:50557 ! Insecta [Term] id: NCBITaxon:862507 name: Mus namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:10088 ! Mus [Term] id: NCBITaxon:8782 name: Aves namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:436492 ! Coelurosauria [Term] id: NCBITaxon:8783 name: Palaeognathae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:8782 ! Aves disjoint_from: NCBITaxon:8825 ! Neognathae [Term] id: NCBITaxon:8798 name: Struthioniformes namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:8783 ! Palaeognathae [Term] id: NCBITaxon:8799 name: Struthionidae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:8798 ! Struthioniformes [Term] id: NCBITaxon:8800 name: Struthio namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:8799 ! Struthionidae [Term] id: NCBITaxon:8801 name: Struthio camelus namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:8800 ! Struthio [Term] id: NCBITaxon:8825 name: Neognathae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:8782 ! Aves [Term] id: NCBITaxon:88770 name: Panarthropoda namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:1206794 ! Ecdysozoa [Term] id: NCBITaxon:8929 name: Columbiformes namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:8825 ! Neognathae [Term] id: NCBITaxon:8930 name: Columbidae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:8929 ! Columbiformes [Term] id: NCBITaxon:89593 name: Craniata namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:7711 ! Chordata [Term] id: NCBITaxon:9254 name: Prototheria namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:40674 ! Mammalia [Term] id: NCBITaxon:9255 name: Monotremata namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:9254 ! Prototheria [Term] id: NCBITaxon:9259 name: Tachyglossidae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:9255 ! Monotremata [Term] id: NCBITaxon:9347 name: Eutheria namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:32525 ! Theria [Term] id: NCBITaxon:9443 name: Primates namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:314146 ! Euarchontoglires [Term] id: NCBITaxon:9526 name: Catarrhini namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:314293 ! Simiiformes [Term] id: NCBITaxon:9604 name: Hominidae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:314295 ! Hominoidea [Term] id: NCBITaxon:9605 name: Homo namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:207598 ! Homininae [Term] id: NCBITaxon:9606 name: Homo sapiens namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:9605 ! Homo [Term] id: NCBITaxon:9989 name: Rodentia namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:314147 ! Glires [Term] id: OBI:0000011 name: planned process def: "A process that realizes a plan which is the concretization of a plan specification." [] is_a: BFO:0000015 ! process [Term] id: OBI:0000679 name: average value def: "A data item that is produced as the output of an averaging data transformation and represents the average value of the input data." [] is_a: IAO:0000027 ! data item [Term] id: PATO:0000001 name: quality namespace: quality def: "A dependent entity that inheres in a bearer by virtue of how the bearer is related to other entities" [PATOC:GVG] is_a: BFO:0000020 ! specifically dependent continuant [Term] id: PATO:0000025 name: composition namespace: quality def: "A single physical entity inhering in an bearer by virtue of the bearer's quantities or relative ratios of subparts." [PATOC:GVG] synonym: "composed of" EXACT [] synonym: "compositionality" EXACT [] synonym: "content" EXACT [] synonym: "structure, composition" EXACT [] is_a: PATO:0000141 ! structure [Term] id: PATO:0000039 name: direction namespace: quality def: "A physical quality inhering in a bearer by virtue of the bearer's orientation in space." [thesaurus.maths:thesaurus.maths] is_a: PATO:0001018 ! physical quality [Term] id: PATO:0000040 name: distance namespace: quality def: "A quality that is the extent of space between two entities." [PATOC:GVG] is_a: PATO:0001018 ! physical quality [Term] id: PATO:0000051 name: morphology namespace: quality def: "A quality of a single physical entity inhering in the bearer by virtue of the bearer's size or shape or structure." [PATOC:GVG] is_a: PATO:0001241 ! physical object quality [Term] id: PATO:0000052 name: shape namespace: quality def: "A morphological quality inhering in a bearer by virtue of the bearer's ratios of distances between its features (points, edges, surfaces and also holes etc)." [PATOC:GVG] synonym: "relational shape quality" EXACT [] is_a: PATO:0000051 ! morphology [Term] id: PATO:0000060 name: spatial pattern namespace: quality def: "A spatial quality inhering in a bearer by virtue of the bearer's exhibiting repetition of placement of its parts." [PATOC:GVG] synonym: "distribution" EXACT [] is_a: PATO:0000051 ! morphology [Term] id: PATO:0000068 name: qualitative namespace: quality def: "A quality of an entity that is descriptive or observational, typically not represented numerically." [https://libguides.macalester.edu/c.php?g=527786&p=3608639, https://www.ncbi.nlm.nih.gov/books/NBK470395/] is_a: PATO:0000001 ! quality [Term] id: PATO:0000069 name: deviation (from_normal) namespace: quality def: "A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average." [PATOC:GVG] is_a: PATO:0000068 ! qualitative [Term] id: PATO:0000070 name: amount namespace: quality def: "The number of entities of this type that are part of the whole organism." [PATOC:GVG] synonym: "presence or absence in organism" EXACT [] synonym: "quantitative" EXACT [] is_a: PATO:0103000 ! quantitative relationship: RO:0015012 PATO:0001555 ! has number of [Term] id: PATO:0000117 name: size namespace: quality def: "A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude." [WordNet:WordNet] is_a: PATO:0000051 ! morphology [Term] id: PATO:0000122 name: length namespace: quality def: "A 1-D extent quality which is equal to the distance between two points." [PATOC:GVG] is_a: PATO:0001708 ! 1-D extent [Term] id: PATO:0000133 name: orientation namespace: quality def: "A spatial quality inhering in a bearer by virtue of the bearer's placement which is defined by the angle between the bearer and an axis, or the angle between the bearer and another object." [PATOC:JE] synonym: "angular placement" EXACT [] is_a: PATO:0000140 ! position [Term] id: PATO:0000136 name: closure namespace: quality def: "A morphological quality pertaining to the degree to which an object contains an opening, aperture, orifice or vent." [PATOC:CJM, PATOC:GVG] is_a: PATO:0000051 ! morphology [Term] id: PATO:0000140 name: position namespace: quality def: "A spatial quality inhering in a bearer by virtue of the bearer's spatial location relative to other objects in the vicinity." [PATOC:GVG] synonym: "location" EXACT [] synonym: "placement" EXACT [] synonym: "relational spatial quality" EXACT [] is_a: PATO:0001018 ! physical quality [Term] id: PATO:0000141 name: structure namespace: quality def: "A morphology quality inhering in a bearer by virtue of the bearer's relative position, shape, arrangements and connectivity of an organism's various parts; the pattern underlying its form." [PATOC:GVG] synonym: "relational structural quality" EXACT [] is_a: PATO:0000051 ! morphology [Term] id: PATO:0000150 name: texture namespace: quality def: "A morphologic quality inhering in a bearer by virtue of the bearer's relative size, organization and distribution of its surface elements or the representation or invention of the appearance of its surface; visual and tactile surface characteristics." [PATOC:GVG] is_a: PATO:0000051 ! morphology [Term] id: PATO:0000261 name: maturity namespace: quality def: "A quality of a single physical entity which is held by a bearer when the latter exhibits a state of growth, differentiation, or development." [Merriam-Webster:Merriam-Webster] is_a: PATO:0001995 ! organismal quality [Term] id: PATO:0000365 name: down namespace: quality def: "A directional quality inhering in a bearer by virtue of the bearer's direction from a higher to a lower point." [PATOC:GVG] is_a: PATO:0000039 ! direction [Term] id: PATO:0000374 name: increased distance namespace: quality def: "A distance which is greater relative to the normal or average." [PATOC:GVG] is_a: PATO:0000040 ! distance is_a: PATO:0002305 ! increased object quality intersection_of: PATO:0000040 ! distance intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal [Term] id: PATO:0000375 name: decreased distance namespace: quality def: "A distance which is lesser relative to the normal or average." [PATOC:GVG] is_a: PATO:0000040 ! distance is_a: PATO:0002303 ! decreased object quality intersection_of: PATO:0000040 ! distance intersection_of: RO:0015008 PATO:0000461 ! decreased in magnitude relative to normal [Term] id: PATO:0000402 name: branched namespace: quality def: "A branchiness quality inhering in a bearer by virtue of the bearer's having branches." [WordNet:WordNet] synonym: "ramified" EXACT [] synonym: "ramiform" EXACT [] is_a: PATO:0002009 ! branchiness [Term] id: PATO:0000404 name: coiled namespace: quality def: "A shape quality inhering in a bearer by virtue of the bearer's being curled or wound (especially in concentric rings or spirals)." [WordNet:WordNet] synonym: "spiral" EXACT [] is_a: PATO:0001794 ! coiling [Term] id: PATO:0000407 name: flat namespace: quality def: "A quality inhering in a bearer by virtue of the bearer's having a horizontal surface without a slope, tilt, or curvature." [web:http\://www.merriam-webster.com/] is_a: PATO:0002254 ! flattened [Term] id: PATO:0000411 name: circular namespace: quality def: "A shape quality inhering in a bearer by virtue of the bearer's being such that every part of the surface or the circumference is equidistant from the center." [thefreedictionary.com:thefreedictionary.com] is_a: PATO:0000947 ! elliptic [Term] id: PATO:0000461 name: normal namespace: quality def: "A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average." [PATOC:GVG] is_a: PATO:0000068 ! qualitative [Term] id: PATO:0000467 name: present namespace: quality def: "A quality inhering in a bearer by virtue of the bearer's existence." [PATOC:GVG] is_a: PATO:0000070 ! amount [Term] id: PATO:0000470 name: increased amount namespace: quality def: "An amount which is relatively high." [PATOC:GVG] synonym: "increased number" EXACT [] synonym: "present in greater numbers in organism" EXACT [] synonym: "supernumerary" EXACT [] is_a: PATO:0000467 ! present is_a: PATO:0002300 ! increased quality intersection_of: PATO:0000070 ! amount intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal [Term] id: PATO:0000573 name: increased length namespace: quality def: "A length quality which is relatively large." [PATOC:GVG] synonym: "long" EXACT [] is_a: PATO:0000122 ! length is_a: PATO:0000586 ! increased size intersection_of: PATO:0000122 ! length intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal [Term] id: PATO:0000574 name: decreased length namespace: quality def: "A length quality which is relatively small." [PATOC:GVG] synonym: "short" EXACT [] is_a: PATO:0000122 ! length is_a: PATO:0000587 ! decreased size intersection_of: PATO:0000122 ! length intersection_of: RO:0015008 PATO:0000461 ! decreased in magnitude relative to normal [Term] id: PATO:0000586 name: increased size namespace: quality def: "A size quality which is relatively high." [PATOC:GVG] is_a: PATO:0000117 ! size is_a: PATO:0002305 ! increased object quality intersection_of: PATO:0000117 ! size intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal [Term] id: PATO:0000587 name: decreased size namespace: quality def: "A size quality which is relatively low." [PATOC:GVG] is_a: PATO:0000117 ! size is_a: PATO:0002303 ! decreased object quality intersection_of: PATO:0000117 ! size intersection_of: RO:0015008 PATO:0000461 ! decreased in magnitude relative to normal [Term] id: PATO:0000591 name: increased thickness namespace: quality def: "A thickness which is relatively high." [PATOC:GVG] synonym: "high thickness" EXACT [] synonym: "stout" EXACT [] synonym: "thickened" EXACT [] is_a: PATO:0000586 ! increased size is_a: PATO:0000915 ! thickness intersection_of: PATO:0000915 ! thickness intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal [Term] id: PATO:0000592 name: decreased thickness namespace: quality def: "A thickness which is relatively low." [PATOC:GVG] synonym: "low thickness" EXACT [] is_a: PATO:0000587 ! decreased size is_a: PATO:0000915 ! thickness intersection_of: PATO:0000915 ! thickness intersection_of: RO:0015008 PATO:0000461 ! decreased in magnitude relative to normal [Term] id: PATO:0000599 name: decreased width namespace: quality def: "A width which is relatively small." [PATOC:GVG] is_a: PATO:0000587 ! decreased size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: RO:0015008 PATO:0000461 ! decreased in magnitude relative to normal [Term] id: PATO:0000600 name: increased width namespace: quality def: "A width which is relatively large." [PATOC:GVG] is_a: PATO:0000586 ! increased size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal [Term] id: PATO:0000608 name: closed namespace: quality def: "A morphological quality inhering in a bearer by virtue of the bearer's affording blocked passage or view." [answers.com:answers.com] is_a: PATO:0000136 ! closure [Term] id: PATO:0000915 name: thickness namespace: quality def: "A 1-D extent quality which is equal to the dimension through an object as opposed to its length or width." [WordNet:WordNet] is_a: PATO:0001708 ! 1-D extent [Term] id: PATO:0000921 name: width namespace: quality def: "A 1-D extent quality which is equal to the distance from one side of an object to another side which is opposite." [PATOC:GVG] is_a: PATO:0001708 ! 1-D extent [Term] id: PATO:0000944 name: sharpness namespace: quality def: "A shape quality inhering in a bearer by virtue of the bearer's having a sharp or tapered end or point." [PATOC:GVG] synonym: "apiculate" EXACT [] is_a: PATO:0000052 ! shape [Term] id: PATO:0000947 name: elliptic namespace: quality def: "A spheroid quality inhering in a bearer by virtue of the bearer's being oval with two axes of symmetry, as produced by a conical section." [PATOC:GVG] synonym: "ellipse-shaped" EXACT [] synonym: "ellipsoid" EXACT [] synonym: "elliptical" EXACT [] is_a: PATO:0002318 ! superelliptic [Term] id: PATO:0000957 name: opacity namespace: quality def: "An optical quality which obtains by virtue of the ability of the bearer to absorb visible light." [PATOC:GVG] is_a: PATO:0001300 ! optical quality [Term] id: PATO:0000963 name: opaque namespace: quality def: "A optical quality inhering in a bearer by virtue of the bearer's not being clear; not transmitting or reflecting light or radiant energy." [PATOC:GVG] synonym: "non-transparent" EXACT [] is_a: PATO:0000957 ! opacity [Term] id: PATO:0000964 name: transparent namespace: quality def: "A optical quality inhering in a bearer by virtue of the bearer's lacking opacity." [PATOC:GVG] synonym: "clear" EXACT [] synonym: "hyaline" EXACT [] is_a: PATO:0000957 ! opacity [Term] id: PATO:0000965 name: symmetry namespace: quality def: "A pattern quality of inhering in a bearer by virtue of the correspondence in size, shape, and relative position of the bearer's parts on opposite sides of a dividing line or median plane or about a center or axis." [PATOC:GVG] is_a: PATO:0000060 ! spatial pattern [Term] id: PATO:0000973 name: porosity namespace: quality def: "A structure quality inhering in a bearer by virtue of the bearer's disposition to admit the passage of gas or liquid through pores or interstices." [PATOC:GVG] is_a: PATO:0000141 ! structure [Term] id: PATO:0000984 name: porous namespace: quality def: "A porosity quality inhering in a bearer by virtue of the bearer's being capable of admitting the passage of gas or liquid through pores or interstices." [PATOC:GVG] is_a: PATO:0000973 ! porosity [Term] id: PATO:0000992 name: viscosity namespace: quality def: "A physical quality of a fluid inhering in a bearer by virtue of the bearer's disposition to internal resistance to flow." [PATOC:GVG] is_a: PATO:0001548 ! quality of a liquid [Term] id: PATO:0000998 name: viscous namespace: quality def: "A viscosity quality inhering in a bearer by virtue of the bearer's having viscosity." [PATOC:GVG] is_a: PATO:0000992 ! viscosity [Term] id: PATO:0001018 name: physical quality namespace: quality def: "A quality of a physical entity that exists through action of continuants at the physical level of organisation in relation to other entities." [PATOC:GVG] synonym: "relational physical quality" EXACT [] xref: Wikipedia:Physical_property is_a: PATO:0001241 ! physical object quality [Term] id: PATO:0001031 name: elasticity namespace: quality def: "A physical quality inhering in a bearer by virtue of the bearer's disposition to recover its size and shape after deformation in any way." [merriam-webster:merriam-webster] is_a: PATO:0001018 ! physical quality [Term] id: PATO:0001154 name: elongated namespace: quality def: "A quality inhering in a bearer by virtue of the bearer's length being notably higher than its width." [WordNet:WordNet] is_a: PATO:0000052 ! shape [Term] id: PATO:0001171 name: elastic namespace: quality def: "An elasticity quality inhering in a bearer by virtue of the bearer's ability to recover its size and shape after deformation in any way." [merriam-webster:merriam-webster] is_a: PATO:0001031 ! elasticity [Term] id: PATO:0001185 name: larval namespace: quality def: "A maturity quality inhering in a bearer by virtue of the bearer's indirect development, undergoing metamorphosis." [Wikipedia:http\://en.wikipedia.org/wiki/Larval] is_a: PATO:0000261 ! maturity [Term] id: PATO:0001187 name: pupal namespace: quality def: "A maturity quality inhering in a insect by virtue of the bearer's being in the chrysalis (cocoon) or post larval stage." [WordNet:WordNet] is_a: PATO:0000261 ! maturity [Term] id: PATO:0001190 name: juvenile namespace: quality def: "A maturity quality inhering in a bearer by virtue the bearer's being not fully grown or developed." [thefreedictionary.com:thefreedictionary.com] is_a: PATO:0000261 ! maturity [Term] id: PATO:0001199 name: linear namespace: quality def: "A shape quality inhering in a bearer by virtue of the bearer's being narrow, with the two opposite margins parallel." [ISBN:0881923214] is_a: PATO:0000052 ! shape [Term] id: PATO:0001241 name: physical object quality namespace: quality def: "A quality which inheres in a continuant." [PATOC:GVG] synonym: "monadic quality of a continuant" EXACT [] synonym: "multiply inhering quality of a physical entity" EXACT [] synonym: "quality of a continuant" EXACT [] synonym: "quality of a single physical entity" EXACT [] synonym: "quality of an object" EXACT [] synonym: "quality of continuant" EXACT [] xref: snap:Quality is_a: BFO:0000019 ! quality is_a: PATO:0000001 ! quality [Term] id: PATO:0001300 name: optical quality namespace: quality def: "An EM radiation quality in which the EM radiation is within the fiat range of the spectrum visible deemed to be light." [PATOC:GVG] is_a: PATO:0070060 ! quality of interaction of a substance with electromagnetic radiation [Term] id: PATO:0001355 name: convex namespace: quality def: "A shape quality that obtains by virtue of the bearer having inward facing edges; having a surface or boundary that curves or bulges outward, as the exterior of a sphere." [PATOC:GVG] is_a: PATO:0002005 ! concavity [Term] id: PATO:0001369 name: raised namespace: quality def: "A shape quality inhering in a colony by virtue of the bearer's appearing above the medium surface with terraced edges." [PATOC:GVG] is_a: PATO:0000052 ! shape [Term] id: PATO:0001374 name: ploidy namespace: quality def: "A cellular quality inhering in a bearer by virtue of the bearer's number of homologous sets of chromosomes in the nucleus or primary chromosome-containing compartment of the cell, each set essentially coding for all the biological traits of the organism." [Wikipedia:http\://en.wikipedia.org/wiki/Ploidy] is_a: PATO:0001396 ! cellular quality [Term] id: PATO:0001375 name: haploid namespace: quality def: "A ploidy quality inhering in a bearer by virtue of the bearer's containing a single set of homologous chromosomes." [Wikipedia:http\://en.wikipedia.org/wiki/Haploid] is_a: PATO:0001393 ! euploid [Term] id: PATO:0001377 name: polyploid namespace: quality def: "A ploidy quality inhering in a bearer by virtue of the bearer's containing more than two homologous sets of chromosomes." [Wikipedia:http\://en.wikipedia.org/wiki/Polyploid] is_a: PATO:0001393 ! euploid [Term] id: PATO:0001393 name: euploid namespace: quality def: "A ploidy quality inhering in a bearer by virtue of the bearer's containing an integral multiple of the monoploid number, possibly excluding the sex-determining chromosomes." [Wikipedia:http\://en.wikipedia.org/wiki/Euploid] is_a: PATO:0001374 ! ploidy [Term] id: PATO:0001394 name: diploid namespace: quality def: "A ploidy quality inhering in a bearer by virtue of the bearer's having two copies (homologs) of each chromosome, usually one from the mother and one from the father." [Wikipedia:http\://en.wikipedia.org/wiki/Diploid] is_a: PATO:0001393 ! euploid [Term] id: PATO:0001396 name: cellular quality namespace: quality def: "A monadic quality of continuant that exists at the cellular level of organisation." [PATOC:GVG] is_a: PATO:0070044 ! anatomical structure quality [Term] id: PATO:0001397 name: cellular potency namespace: quality def: "A cellular quality that arises by virtue of whether the bearer's disposition to differentiate into one or more mature cell types." [PATOC:GVG] is_a: PATO:0001396 ! cellular quality [Term] id: PATO:0001400 name: unipotent namespace: quality def: "A cellular potency that is the capacity to produce only one differentiated cell type." [Wikipedia:http\://en.wikipedia.org/wiki/Unipotent] is_a: PATO:0001397 ! cellular potency [Term] id: PATO:0001401 name: oligopotent namespace: quality def: "A cellular potency that is the capacity to form multiple differentiated cell types of a specific lineage and lack self renewing capacity." [PATOC:MAH] is_a: PATO:0001397 ! cellular potency [Term] id: PATO:0001402 name: multipotent namespace: quality def: "A cellular potency that is the capacity to form multiple differentiated cell types." [Wikipedia:http\://en.wikipedia.org/wiki/Multipotent] is_a: PATO:0001397 ! cellular potency [Term] id: PATO:0001404 name: nucleate quality namespace: quality def: "A cellular quality inhering in a bearer by virtue of bearer's number of nuclei." [PATOC:GVG] is_a: PATO:0001396 ! cellular quality [Term] id: PATO:0001405 name: anucleate namespace: quality def: "A nucleate quality inhering in a bearer by virtue of the bearer's having no nucleus." [Biology-online:Biology-online] is_a: PATO:0001404 ! nucleate quality [Term] id: PATO:0001406 name: binucleate namespace: quality def: "A nucleate quality inhering in a bearer by virtue of the bearer's having two nuclei." [Biology-online:Biology-online] is_a: PATO:0001908 ! multinucleate [Term] id: PATO:0001407 name: mononucleate namespace: quality def: "A nucleate quality inhering in a bearer by virtue of the bearer's having one nucleus." [Biology-online:Biology-online] is_a: PATO:0002505 ! nucleated [Term] id: PATO:0001408 name: ciliatedness namespace: quality def: "A cellular quality inhering in a bearer by virtue of the bearer's having thin, tail-like projections extending outwards from the cell body." [Wikipedia:http\://en.wikipedia.org/wiki/Ciliated] is_a: PATO:0001396 ! cellular quality [Term] id: PATO:0001410 name: striated namespace: quality def: "A shape quality inhering in a bearer by virtue of the bearer's being marked by narrow lines or grooves, usually parallel." [Biology-online:Biology-online] is_a: PATO:0000052 ! shape [Term] id: PATO:0001419 name: sharp namespace: quality def: "A shape quality inhering in a bearer by virtue of the bearer's terminating in a point or edge." [PATOC:GVG] is_a: PATO:0000944 ! sharpness [Term] id: PATO:0001475 name: increased position namespace: quality def: "A position which is relatively high." [PATOC:GVG] is_a: PATO:0000140 ! position is_a: PATO:0002305 ! increased object quality intersection_of: PATO:0000140 ! position intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal [Term] id: PATO:0001476 name: decreased position namespace: quality def: "A positional which is relatively low." [PATOC:GVG] is_a: PATO:0000140 ! position is_a: PATO:0002303 ! decreased object quality intersection_of: PATO:0000140 ! position intersection_of: RO:0015008 PATO:0000461 ! decreased in magnitude relative to normal [Term] id: PATO:0001500 name: tapered namespace: quality def: "A shape quality inhering in a bearer by virtue of the bearer's being gradually narrower or thinner toward one end." [WordNet:WordNet] synonym: "taper" EXACT [] is_a: PATO:0001419 ! sharp [Term] id: PATO:0001501 name: immature namespace: quality def: "A quality inhering in a bearer by virtue of the bearer's lacking complete growth, differentiation, or development." [Merriam-Webster:Merriam-Webster] is_a: PATO:0000261 ! maturity [Term] id: PATO:0001543 name: flexibility namespace: quality def: "A physical quality inhering in a bearer by virtue of the bearer's disposition to being turned, bowed, or twisted without breaking." [merriam-webster:merriam-webster] is_a: PATO:0001546 ! quality of a solid [Term] id: PATO:0001546 name: quality of a solid namespace: quality def: "A physical quality inhering in a bearer by virtue of the bearer's exhibiting the physical characteristics of an entity characterized by particles arranged such that their shape and volume are relatively stable." [Chemistry:http\://chemistry.about.com/od/chemistryglossary/a/soliddefinition.htm] synonym: "solidity" EXACT [] is_a: PATO:0002198 ! quality of a substance [Term] id: PATO:0001547 name: quality of a gas namespace: quality def: "A physical quality inhering in a bearer by virtue of the bearer's exhibiting the physical characteristics of an entity consisting of particles that have neither a defined volume nor defined shape." [Chemistry:http\://chemistry.about.com/od/chemistryglossary/a/gasdefinition.htm, PATOC:GVG] synonym: "gaseous" EXACT [] is_a: PATO:0002198 ! quality of a substance [Term] id: PATO:0001548 name: quality of a liquid namespace: quality def: "A physical quality inhering in an entity exhibiting the physical characteristics of an amorphous (non-crystalline) form of matter between a gas and a solid that has a definite volume, but no definite shape." [url:http\://www.chemistry-dictionary.com/definition/liquid.php] synonym: "liquidity" EXACT [] is_a: PATO:0002198 ! quality of a substance [Term] id: PATO:0001555 name: has number of namespace: quality def: "The number of parts of a particular type that the bearer entity has. This is a relational quality, and thus holds between two entities: the bearer of the quality, and the type of parts." [PATOC:CJM] synonym: "extra or missing physical or functional parts" EXACT [] synonym: "has or lacks parts of type" EXACT [] synonym: "mereological quality" EXACT [] synonym: "number of" EXACT [] xref: OBO_REL:has_part is_a: PATO:0000070 ! amount [Term] id: PATO:0001571 name: dilated namespace: quality def: "A size quality inhering in a bearer by virtue of the bearer's being made wider or larger in all dimensions." [WordNet:WordNet] is_a: PATO:0000586 ! increased size [Term] id: PATO:0001573 name: isometrical namespace: quality def: "A symmetry quality inhering in a bearer by virtue of the bearer's having equal dimensions or measurements." [WordNet:WordNet] is_a: PATO:0000965 ! symmetry [Term] id: PATO:0001579 name: contractility namespace: quality def: "A physical quality that is the ability to contract or shrink." [WordNet:WordNet] is_a: PATO:0001018 ! physical quality [Term] id: PATO:0001591 name: curvature namespace: quality def: "A surface shape quality inhering in a bearer by virtue of the bearer's exhibiting a degree of bending." [WordNet:WordNet] is_a: PATO:0000052 ! shape [Term] id: PATO:0001690 name: contractile namespace: quality def: "A contractility quality inhering in a bearer by virtue of the bearer's ability of contracting or being contracted." [PATOC:GVG] is_a: PATO:0001579 ! contractility [Term] id: PATO:0001708 name: 1-D extent namespace: quality def: "A size quality inhering in an bearer by virtue of the bearer's extension in one dimension." [PATOC:GVG] synonym: "1-D size" EXACT [] is_a: PATO:0000117 ! size [Term] id: PATO:0001735 name: liquid configuration namespace: quality def: "A physical quality inhering in a bearer by virtue of the bearer's parts having the arrangement which exhibits characteristics of liquids." [PATOC:GVG] synonym: "liquid" EXACT [] is_a: PATO:0001548 ! quality of a liquid [Term] id: PATO:0001736 name: solid configuration namespace: quality def: "A physical quality inhering in a bearer by virtue of the bearer's parts having the arrangement which exhibits characteristics of solids." [PATOC:GVG] synonym: "solid" EXACT [] is_a: PATO:0001546 ! quality of a solid [Term] id: PATO:0001748 name: invaginated namespace: quality def: "A shape quality in which a portion of the outermost boundary of an entity folds in space such that a portion that was originally convex is now concave." [PATOC:GVG] is_a: PATO:0001857 ! concave [Term] id: PATO:0001794 name: coiling namespace: quality def: "A shape quality inhering in a bearer by virtue of the bearer's being wound in a continuous series of loops." [Online_Dictionary:Online_Dictionary] is_a: PATO:0000052 ! shape [Term] id: PATO:0001795 name: increased coiling namespace: quality def: "A coiling which is relatively high." [PATOC:GVG] synonym: "high coiling" EXACT [] is_a: PATO:0000404 ! coiled is_a: PATO:0002305 ! increased object quality intersection_of: PATO:0000404 ! coiled intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal [Term] id: PATO:0001796 name: decreased coiling namespace: quality def: "A coiling which is relatively low." [PATOC:GVG] synonym: "low coiling" EXACT [] is_a: PATO:0000404 ! coiled is_a: PATO:0002303 ! decreased object quality intersection_of: PATO:0000404 ! coiled intersection_of: RO:0015008 PATO:0000461 ! decreased in magnitude relative to normal [Term] id: PATO:0001847 name: constricted namespace: quality def: "A structural quality inhering in a bearer by virtue of the bearer's being drawn together, compressed or squeezed physically." [WordNet:WordNet] synonym: "stenosis" EXACT [] synonym: "stenotic" EXACT [] synonym: "stricture" EXACT [] is_a: PATO:0000141 ! structure [Term] id: PATO:0001857 name: concave namespace: quality def: "A shape quality in a bearer by virtue of the bearer's curving inward." [WordNet:WordNet] is_a: PATO:0002005 ! concavity [Term] id: PATO:0001873 name: cylindrical namespace: quality def: "A convex 3-D shape quality inhering in a bearer by virtue of the bearer's exhibiting a consistently-sized round cross section." [PATOC:MAH] synonym: "rod-like" EXACT [] synonym: "rod-shaped" EXACT [] is_a: PATO:0002007 ! convex 3-D shape relationship: RO:0015011 PATO:0000411 ! has cross section circular [Term] id: PATO:0001901 name: back namespace: quality def: "A directional quality inhering in a bearer by virtue of the bearer's direction that is similar to the direction of an object to the north when it faces south." [PATOC:GVG] is_a: PATO:0000039 ! direction [Term] id: PATO:0001908 name: multinucleate namespace: quality def: "A nucleate quality inhering in a bearer by virtue of the bearer's having more than one nucleus." [PATOC:GVG] is_a: PATO:0002505 ! nucleated [Term] id: PATO:0001987 name: saccular namespace: quality def: "A structural quality inhering in a bearer by virtue of the bearer's having a three dimensional cavity with a narrow or no opening, and often containing an anatomical substance." [PATOC:MAH] synonym: "sacular" EXACT [] is_a: PATO:0002014 ! structure, cavities [Term] id: PATO:0001992 name: cellularity namespace: quality def: "An organismal quality inhering in a bearer by virtue of the bearer's consisting cells." [PATOC:GVG] is_a: PATO:0001995 ! organismal quality [Term] id: PATO:0001993 name: multicellular namespace: quality def: "A cellularity quality inhering in a bearer by virtue of the bearer's consisting of more than one cell." [PATOC:GVG] is_a: PATO:0001992 ! cellularity [Term] id: PATO:0001995 name: organismal quality namespace: quality def: "A quality that inheres in an entire organism or part of an organism." [PATOC:CJM] is_a: PATO:0001241 ! physical object quality [Term] id: PATO:0001997 name: decreased amount namespace: quality def: "An amount which is relatively low." [PATOC:GVG] synonym: "decreased number" EXACT [] synonym: "present in fewer numbers in organism" EXACT [] is_a: PATO:0000467 ! present is_a: PATO:0002301 ! decreased quality intersection_of: PATO:0000070 ! amount intersection_of: RO:0015008 PATO:0000461 ! decreased in magnitude relative to normal [Term] id: PATO:0002005 name: concavity namespace: quality def: "Surface shape that refers to the inward or outward curvature of the surface." [PATOC:MAH] is_a: PATO:0000052 ! shape [Term] id: PATO:0002006 name: 2-D shape namespace: quality def: "A shape that inheres in a 2 dimensional entity, such as a cross section or projection of a 3 dimensional entity." [PATOC:CJM] is_a: PATO:0000052 ! shape [Term] id: PATO:0002007 name: convex 3-D shape namespace: quality def: "A complete three dimensional shape in which for every line connecting pair of points on the object is within the object. Or: a shape lacking cavities. Contrast: concave." [PATOC:CJM] xref: Image:http\://upload.wikimedia.org/wikipedia/commons/0/06/Convex_polygon_illustration1.png is_a: PATO:0002266 ! 3-D shape relationship: RO:0015011 PATO:0002006 ! has cross section 2-D shape [Term] id: PATO:0002009 name: branchiness namespace: quality def: "A shape quality inhering in a bearer by virtue of the degree to which there are subdivisions or offshoots in a bearer entity." [PATOC:MAH] is_a: PATO:0000052 ! shape [Term] id: PATO:0002014 name: structure, cavities namespace: quality def: "A structural quality that inheres in a bearer by virtue of the bearer's containing hollow areas." [PATOC:GVG] is_a: PATO:0000141 ! structure [Term] id: PATO:0002021 name: conical namespace: quality def: "A convex 3-D shape quality inhering in a bearer by virtue of the bearer's resembling a cone (a 3-D shape with a round cross section that tapers)." [Wikipedia:http\://en.wikipedia.org/wiki/Cone_(geometry)] synonym: "cone-shaped" EXACT [] xref: Image:http\://upload.wikimedia.org/wikipedia/commons/d/d2/Cone_3d.png is_a: PATO:0002007 ! convex 3-D shape [Term] id: PATO:0002039 name: biconcave namespace: quality def: "A concave quality inhering in a bearer by virtue of the bearer's curving inward on both sides or surfaces." [PATOC:GVG] is_a: PATO:0001857 ! concave [Term] id: PATO:0002045 name: dendritic namespace: quality def: "A branched quality inhering in a bearer by virtue of the bearer's having smaller branches arising from larger branches. Resembling a tree in branching structure." [PATOC:cvs] synonym: "dendriform" EXACT [] synonym: "dendroid" EXACT [] synonym: "dendroidal" EXACT [] is_a: PATO:0000402 ! branched creation_date: 2009-02-15T08:11:41Z [Term] id: PATO:0002078 name: hollow namespace: quality def: "A quality inhering in a bearer by virtue of the bearer's having an empty space or cavity within." [url:http\://www.merriam-webster.com/dictionary/hollow] is_a: PATO:0002014 ! structure, cavities creation_date: 2009-09-18T02:19:20Z [Term] id: PATO:0002094 name: basophilic namespace: quality def: "An affinity inhering in an anatomical structure by virtue of the bearer exhibiting a molecular interaction for basic dyes under specific pH conditions." [PATOC:GVG] is_a: PATO:0070045 ! anatomical histological quality creation_date: 2009-10-05T12:05:23Z [Term] id: PATO:0002124 name: laminar namespace: quality def: "A quality inhering in a bearer by virtue of the bearer's processing the form of a thin plate sheet or layer." [PATOC:GVG] is_a: PATO:0000141 ! structure creation_date: 2009-10-06T04:37:14Z [Term] id: PATO:0002198 name: quality of a substance namespace: quality def: "A quality inhering in a bearer by virtue of its constitution." [PATOC:GVG] is_a: PATO:0001018 ! physical quality creation_date: 2010-03-15T04:35:27Z [Term] id: PATO:0002219 name: fan-shaped namespace: quality def: "A quality inhering in a bearer that is shaped in the form of a fan." [thefreedictionary:http\://www.thefreedictionary.com/fan-shaped] synonym: "fan-like" EXACT [] is_a: PATO:0002006 ! 2-D shape creation_date: 2010-07-09T01:43:42Z [Term] id: PATO:0002226 name: subcylindrical namespace: quality def: "A cylindrical shape quality inhering in a bearer by virtue of the bearer's being imperfectly cylindrical or approximately cylindrical." [url:http\://www.thefreedictionary.com/Subcylindrical] is_a: PATO:0001873 ! cylindrical creation_date: 2010-07-13T04:22:30Z [Term] id: PATO:0002228 name: acuminate namespace: quality def: "A tapered shape quality inhering in a bearer by virtue of the bearer's tapering gradually to a sharp point." [url:http\://www.thefreedictionary.com/acuminate] is_a: PATO:0001500 ! tapered creation_date: 2010-07-15T09:03:18Z [Term] id: PATO:0002254 name: flattened namespace: quality def: "A quality inhering in a bearer by virtue of the bearer's surface becoming more extended in a plane." [PATOC:CVS] is_a: PATO:0001591 ! curvature creation_date: 2010-08-16T03:59:34Z [Term] id: PATO:0002255 name: grooved namespace: quality def: "Texture quality inhering in a bearer by virtue of the bearer's being marked with one or more channels." [PATOC:JE] is_a: PATO:0000150 ! texture creation_date: 2010-09-01T10:27:48Z [Term] id: PATO:0002258 name: pointed namespace: quality def: "A shape quality inhering in a bearer by virtue of the bearer's having a point." [PATOC:http\://www.merriam-webster.com/dictionary/pointed] is_a: PATO:0001419 ! sharp creation_date: 2010-09-08T03:15:16Z [Term] id: PATO:0002266 name: 3-D shape namespace: quality def: "A shape that inheres in a 3 dimensional entity." [PATOC:OREGON] is_a: PATO:0000052 ! shape creation_date: 2010-10-05T12:31:16Z [Term] id: PATO:0002287 name: increased elasticity namespace: quality def: "An elasticity which is relatively high." [PATOC:GVG] is_a: PATO:0001171 ! elastic is_a: PATO:0002305 ! increased object quality intersection_of: PATO:0001171 ! elastic intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal creation_date: 2011-03-30T11:50:21Z [Term] id: PATO:0002288 name: decreased elasticity namespace: quality def: "An elasticity which is relatively low." [PATOC:GVG] is_a: PATO:0001171 ! elastic is_a: PATO:0002303 ! decreased object quality intersection_of: PATO:0001171 ! elastic intersection_of: RO:0015008 PATO:0000461 ! decreased in magnitude relative to normal creation_date: 2011-03-30T11:50:39Z [Term] id: PATO:0002299 name: tubular namespace: quality def: "A cylindrical shape that is hollow." [PATOC:GVG] synonym: "tube like" EXACT [] synonym: "tube-shaped" EXACT [] synonym: "tubulate" EXACT [] is_a: PATO:0001873 ! cylindrical is_a: PATO:0002078 ! hollow creation_date: 2011-06-08T06:33:50Z [Term] id: PATO:0002300 name: increased quality namespace: quality def: "A quality that has a value that is increased compared to normal or average." [PATOC:GVG] is_a: PATO:0000069 ! deviation (from_normal) intersection_of: PATO:0000001 ! quality intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal relationship: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal creation_date: 2011-06-16T06:39:43Z [Term] id: PATO:0002301 name: decreased quality namespace: quality def: "A quality that has a value that is decreased compared to normal or average." [PATOC:GVG] is_a: PATO:0000069 ! deviation (from_normal) intersection_of: PATO:0000001 ! quality intersection_of: RO:0015008 PATO:0000461 ! decreased in magnitude relative to normal relationship: RO:0015008 PATO:0000461 ! decreased in magnitude relative to normal creation_date: 2011-06-16T06:40:15Z [Term] id: PATO:0002303 name: decreased object quality namespace: quality def: "A quality of an object that has a value that is decreased compared to normal or average." [PATOC:GVG] is_a: PATO:0001241 ! physical object quality is_a: PATO:0002301 ! decreased quality intersection_of: PATO:0001241 ! physical object quality intersection_of: RO:0015008 PATO:0000461 ! decreased in magnitude relative to normal creation_date: 2011-06-16T06:51:54Z [Term] id: PATO:0002305 name: increased object quality namespace: quality def: "A quality of an object that has a value that is increased compared to normal or average." [PATOC:GVG] is_a: PATO:0001241 ! physical object quality is_a: PATO:0002300 ! increased quality intersection_of: PATO:0001241 ! physical object quality intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal creation_date: 2011-06-16T06:54:01Z [Term] id: PATO:0002309 name: fiber shaped namespace: quality def: "A convex 3-D shape quality inhering in a bearer by virtue of the bearer's exhibiting a by virtue of the bearer's exhibiting a consistently sized and approximately round cross-section along its length, which is many times larger than its diameter." [PATOC:DC] is_a: PATO:0002226 ! subcylindrical creation_date: 2011-09-09T04:50:10Z [Term] id: PATO:0002318 name: superelliptic namespace: quality def: "A shape constituting a transition between a rectangle and a circle; a closed curve, of which the circle and ellipse are special cases, whose parametric equation is x = a.cos2/rt, y = b.cos2/rt" [wiktionary:superellipse] synonym: "Lamé curve" EXACT [] is_a: PATO:0002006 ! 2-D shape creation_date: 2011-10-12T12:45:16Z [Term] id: PATO:0002326 name: angle namespace: quality def: "An orientation inhering in a bearer by virtue of the bearer's placement at an angle." [PATOC:GVG] is_a: PATO:0000133 ! orientation creation_date: 2011-11-23T12:06:09Z [Term] id: PATO:0002327 name: increased angle to namespace: quality def: "An angle which is relatively high." [PATOC:GVG] is_a: PATO:0001475 ! increased position is_a: PATO:0002326 ! angle intersection_of: PATO:0002326 ! angle intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal creation_date: 2011-11-23T12:06:38Z [Term] id: PATO:0002328 name: decreased angle to namespace: quality def: "An angle which is relatively low." [PATOC:GVG] is_a: PATO:0001476 ! decreased position is_a: PATO:0002326 ! angle intersection_of: PATO:0002326 ! angle intersection_of: RO:0015008 PATO:0000461 ! decreased in magnitude relative to normal creation_date: 2011-11-23T12:06:54Z [Term] id: PATO:0002418 name: acidophilic namespace: quality def: "An affinity inhering in an anatomical structure by virtue of the bearer exhibiting a molecular interaction for acidic dyes under specific pH conditions." [PATOC:GVG] synonym: "eosinophilic" EXACT [] is_a: PATO:0070045 ! anatomical histological quality creation_date: 2012-12-17T03:01:19Z [Term] id: PATO:0002422 name: acinar namespace: quality def: "Pertaining to the individual parts making up an aggregate fruit like a many-lobed \"berry,\" such as a raspberry." [wikipedia:https\://en.wikipedia.org/wiki/Acinus] is_a: PATO:0000141 ! structure creation_date: 2012-12-17T03:11:10Z [Term] id: PATO:0002462 name: collagenous namespace: quality def: "A composition quality inhering in an bearer by virtue of the bearer's consisting of collagen." [PATOC:WD] is_a: PATO:0000025 ! composition creation_date: 2013-09-15T11:34:15Z [Term] id: PATO:0002468 name: distensible namespace: quality def: "A structure quality inhering in a bearer by virtue of the bearer's being capable of swelling or stretching." [PATOC:WD] is_a: PATO:0015008 ! distensibility creation_date: 2013-09-15T11:48:26Z [Term] id: PATO:0002478 name: transversely striated namespace: quality def: "A shape quality inhering in a bearer by virtue of the bearer's being marked by narrow lines or grooves, usually parallel, that are oriented transversely relative to the long axis of the bearer." [PATOC:DS] is_a: PATO:0001410 ! striated creation_date: 2013-09-15T12:29:15Z [Term] id: PATO:0002505 name: nucleated namespace: quality def: "A nucleate quality inhering in a bearer by virtue of the bearer's having one or more nucleus." [PATOC:GVG] is_a: PATO:0001404 ! nucleate quality creation_date: 2013-10-21T05:44:34Z [Term] id: PATO:0002539 name: ring shaped namespace: quality def: "A shape quality inhering in a bearer by virtue of the bearer's having a shape like a ring (a circular shape enclosing a space)." [PATOC:WD] synonym: "annular" EXACT [] synonym: "ring-shaped" EXACT [] is_a: PATO:0000947 ! elliptic creation_date: 2014-08-12T12:01:56Z [Term] id: PATO:0010001 name: disconnected namespace: quality def: "A structural quality inhering in the bearer by virtue of the bearer consisting of multiple structures lacking any physical connection to each other." [GOC:dos] is_a: PATO:0000141 ! structure creation_date: 2014-12-12T08:43:17Z [Term] id: PATO:0015006 name: polymeric namespace: quality def: "A quality inhering in a structure by virtue of it consisting of many of repeated, similar or identical subunits, arranged in some orderly array." [GOC:DOS, https://github.com/pato-ontology/pato/issues/78] is_a: PATO:0000141 ! structure [Term] id: PATO:0015008 name: distensibility namespace: quality def: "A quality inhering in a bearer by virtue of the extent to which the bearer is capable of being stretched or swollen." [GOC:CJM] is_a: PATO:0000141 ! structure [Term] id: PATO:0015024 name: increased porosity namespace: quality def: "An increase in porosity." [https://github.com/pato-ontology/pato/issues/110] is_a: PATO:0000973 ! porosity is_a: PATO:0002305 ! increased object quality intersection_of: PATO:0000973 ! porosity intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal [Term] id: PATO:0015025 name: decreased porosity namespace: quality def: "An decrease in porosity." [https://github.com/pato-ontology/pato/issues/110] is_a: PATO:0000973 ! porosity is_a: PATO:0002303 ! decreased object quality intersection_of: PATO:0000973 ! porosity intersection_of: RO:0015008 PATO:0000461 ! decreased in magnitude relative to normal [Term] id: PATO:0040024 name: bilaterally paired namespace: quality def: "The bearer of this quality has_part n=2 of the indicated entity type, where n is unpaired for a comparable organism." [https://orcid.org/0000-0003-3162-7490] is_a: PATO:0000467 ! present [Term] id: PATO:0040072 name: high nuclear/cytoplasmic ratio namespace: quality def: "A quality inhering in a cell by virtue of the cell having a high nuclear/cytoplasmic ratio." [http://lymerick.net/blood-cells.pdf, Wikipedia:NC_ratio&oldid=931936284] synonym: "high N:C ratio" EXACT [] is_a: PATO:0001396 ! cellular quality [Term] id: PATO:0070044 name: anatomical structure quality namespace: quality def: "A quality of continuant that exist at the anatomical level of organisation and anything under it. This includes, but is not limited to, cells , tissues, and components." [] is_a: PATO:0001241 ! physical object quality [Term] id: PATO:0070045 name: anatomical histological quality namespace: quality def: "A quality inhering in an anotomical structure by virtue of its capacity to be stained by specific histological dyes." [] is_a: PATO:0070044 ! anatomical structure quality [Term] id: PATO:0070046 name: neutrophillic namespace: quality def: "An affinity inhering in an anatomical structure by virtue of the bearer exhibiting a molecular interaction that stains and colors, pale-pink, with Wright-Giemsa stain." [GOC:add] is_a: PATO:0070045 ! anatomical histological quality [Term] id: PATO:0070047 name: polychromatophilic namespace: quality def: "An affinity inhering in an anatomical structure by virtue of the bearer exhibiting a molecular interaction for both basic and acid stains under specific pH conditions." [GOC:add] is_a: PATO:0070045 ! anatomical histological quality [Term] id: PATO:0070060 name: quality of interaction of a substance with electromagnetic radiation namespace: quality def: "A quality of a substance on which or through which electromagnetic radiation impinges or traverses with respect to radiation. This substance quality changes the quality of the incident radiation with respect to any of: intensity, direction, scatter and wavelength." [https://orcid.org/0000-0002-5111-7263] is_a: PATO:0002198 ! quality of a substance [Term] id: PATO:0103000 name: quantitative namespace: quality def: "A quality of an entity that can be represented numerically, including anything that can be counted, measured, or given a numerical value." [https://libguides.macalester.edu/c.php?g=527786&p=3608639, https://www.nnlm.gov/guides/data-glossary/quantitative-data] is_a: PATO:0000001 ! quality [Term] id: PR:000000001 name: protein namespace: protein def: "An amino acid chain that is canonically produced de novo by ribosome-mediated translation of a genetically-encoded mRNA, and any derivatives thereof." [PRO:DAN, PRO:WCB] synonym: "natural protein" EXACT [PRO:DAN] is_a: PR:000018263 ! amino acid chain is_a: PR:000050567 ! protein-containing material entity intersection_of: PR:000018263 ! amino acid chain intersection_of: PR:000018263 ! amino acid chain intersection_of: has_gene_template SO:0000704 ! gene intersection_of: has_gene_template SO:0001217 ! protein_coding_gene intersection_of: RO:0002353 GO:0006412 ! output of translation intersection_of: RO:0002353 GO:0006412 ! output of translation relationship: has_gene_template SO:0001217 ! protein_coding_gene relationship: RO:0002353 GO:0006412 ! output of translation [Term] id: PR:000001002 name: CD19 molecule namespace: protein def: "A protein that is a translation product of the human CD19 gene or a 1:1 ortholog thereof. It is composed of an N-terminal extracellular domain containing two Ig-like C2-type (immunoglobulin-like) domains, followed by a single-pass transmembrane segment and a cytoplasmic C-terminal tail. CD19 expression is restricted to members of the B cell lineage. It functions as a co-receptor for B-cell antigen receptor (BCR), regulating signal transduction." [PMID:15778510] synonym: "B-lymphocyte surface antigen B4" EXACT [] synonym: "differentiation antigen CD19" EXACT [] synonym: "T-cell surface antigen Leu-12" EXACT [] xref: IUPHARobj:2764 xref: PIRSF:PIRSF016630 is_a: PR:000000001 ! protein [Term] id: PR:000001003 name: CD34 molecule namespace: protein def: "A protein that is a translation product of the human CD34 gene or a 1:1 ortholog thereof. It is a leukocyte membrane protein expressed specifically by lymphohematopoietic progenitor cells. It contains a single-pass transmembrane domain and that show distinct expression on early hematopoietic precursors and vascular-associated tissue. Acts as a scaffold that presents selectin carbohydrate ligands in a clustered, tissue specific manner to allow for higher avidity interactions between leukocytes and endothelial cells during the inflammatory process. In common with related sialomucins (endoglycan and podocalyxin), the extracellular region is dominated by an N-terminal mucin-like domain, which is densely substituted with sialylated O-linked carbohydrates. The mucin-like region is followed by a cysteine-containing and presumably globular domain. This domain may fold into an immunoglobulin-like structure as the positions of 2 of the cysteines are conserved in the C2 set of the immunoglobulin superfamily. The cytoplasmic domain is around 73-76 residues long and highly conserved." [PMID:16720896, PMID:8983065] synonym: "hematopoietic progenitor cell antigen CD34" EXACT [] xref: PIRSF:PIRSF028749 is_a: PR:000000001 ! protein [Term] id: PR:000001004 name: CD4 molecule namespace: protein def: "A protein that is a translation product of the human CD4 gene or a 1:1 ortholog thereof. CD4 is an accessory protein for MHC class-II antigen/T-cell receptor interaction. It is the primary receptor for HIV-1. CD4 has four immunoglobulin-like domains in its extracellular region that share the same structure, but can differ in sequence." [PMID:15326605] synonym: "T-cell differentiation antigen L3T4" EXACT [] synonym: "T-cell surface antigen T4/Leu-3" EXACT [] synonym: "T-cell surface glycoprotein CD4" EXACT [] xref: PIRSF:PIRSF001977 is_a: PR:000000001 ! protein [Term] id: PR:000001005 name: integrin alpha with A domain namespace: protein def: "An integrin alpha that contains an A domain. A hallmark of this class is the presence of a von Willebrand factor type A domain (Pfam:PF00092) (I-domain) of approximately 200 amino acid residues at the N terminus, which confers divalent cation binding properties. Unlike other integrin alpha proteins, they do not undergo proteolytic cleavage." [PIRSF:PIRSF002497] synonym: "integrin alpha with I domain" EXACT [] xref: PIRSF:PIRSF002497 is_a: PR:000025796 ! integrin alpha [Term] id: PR:000001012 name: integrin alpha-M namespace: protein def: "An integrin alpha with A domain that is a translation product of the human ITGAM gene or a 1:1 ortholog thereof. They constitute subunits of the integrin alpha-M/beta-2 receptor. This receptor is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is also a receptor for fibrinogen, factor X and ICAM1." [UniProtKB:P11215] synonym: "CD11 antigen-like family member B" EXACT [] synonym: "CD11b" EXACT [] synonym: "cell surface glycoprotein MAC-1 subunit alpha" EXACT [] synonym: "CR-3 alpha chain" EXACT [] synonym: "leukocyte adhesion receptor MO1" EXACT [] synonym: "neutrophil adherence receptor" EXACT [] xref: IUPHARobj:2452 is_a: PR:000001005 ! integrin alpha with A domain [Term] id: PR:000001018 name: CD3 subunit with immunoglobulin domain namespace: protein def: "A protein that has a core domain composition consisting of an extracellular N-terminal domain that adopts an immunoglobulin fold, a transmembrane domain, and an intracellular C-terminal domain with a single copy of the Immunoreceptor tyrosine-based activation motif (Pfam:PF02189) (ITAM). It constitutes the invariant subunit of the T cell antigen receptor (TCR). TCR is a surface receptor on T cells responsible for recognizing MHC-restricted antigens and initiating the cellular immune response." [PMID:16473826, PMID:1724736] synonym: "CD3 subunit with Ig-like domain" EXACT [] xref: PIRSF:PIRSF001993 is_a: PR:000000001 ! protein [Term] id: PR:000001020 name: CD3 epsilon namespace: protein def: "A CD3 subunit with immunoglobulin domain that is a translation product of the human CD3E gene or a 1:1 ortholog thereof." [PRO:CNA] synonym: "CD3e" EXACT [] synonym: "T-cell surface antigen T3/Leu-4 epsilon chain" EXACT [] xref: IUPHARobj:2742 is_a: PR:000001018 ! CD3 subunit with immunoglobulin domain [Term] id: PR:000001022 name: neural cell adhesion molecule namespace: protein def: "A protein with a domain composition consisting of a large extracellular domain, including five Ig-like C2-type domains followed by two copies of the Fibronectin type-III domain (Pfam:PF00041), a single-pass transmembrane domain and a short cytoplasmic C-terminal domain." [PRO:CNA] xref: PIRSF:PIRSF002507 is_a: PR:000000001 ! protein [Term] id: PR:000001023 name: neural cell adhesion molecule NCAM namespace: protein def: "A neural cell adhesion molecule that is involved in neuronal development, synaptic plasticity, and regeneration." [PMID:17975827] xref: PIRSF:PIRSF501037 is_a: PR:000001022 ! neural cell adhesion molecule [Term] id: PR:000001024 name: neural cell adhesion molecule 1 namespace: protein def: "A neural cell adhesion molecule NCAM that is a translation product of the human NCAM1 gene or a 1:1 ortholog thereof." [PRO:CNA] synonym: "CD56" EXACT [] synonym: "N-CAM-1" EXACT [] synonym: "NCAM-1" EXACT [] xref: IUPHARobj:2769 is_a: PR:000001023 ! neural cell adhesion molecule NCAM [Term] id: PR:000001083 name: CD2 molecule namespace: protein def: "A protein that is a translation product of the human CD2 gene or a 1:1 ortholog thereof." [PRO:CNA] synonym: "erythrocyte receptor" EXACT [] synonym: "LFA-2" EXACT [] synonym: "LFA-3 receptor" EXACT [] synonym: "ly-37" EXACT [] synonym: "lymphocyte antigen 37" EXACT [] synonym: "rosette receptor" EXACT [] synonym: "T-cell surface antigen CD2" EXACT [] synonym: "T-cell surface antigen T11/Leu-5" EXACT [] synonym: "T-cell surface glycoprotein CD2" EXACT [] xref: IUPHARobj:2600 xref: PIRSF:PIRSF001984 is_a: PR:000000001 ! protein [Term] id: PR:000001084 name: T-cell surface glycoprotein CD8 alpha chain namespace: protein def: "A protein that is a translation product of the human CD8A gene or a 1:1 ortholog thereof. CD8 is a transmembrane that is a co-receptor for MHC class-I antigen/T-cell receptor interaction. The most common form of CD8 is composed of a CD8 alpha and a CD8 beta chain." [PMID:11114424, PRO:CNA, Wikipedia:CD8] synonym: "CD8a" EXACT [] synonym: "T-cell surface glycoprotein Lyt-2" EXACT [] synonym: "T-lymphocyte differentiation antigen T8/Leu-2" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:000001289 name: membrane-spanning 4-domains subfamily A member 1 namespace: protein def: "A protein that is a translation product of the human MS4A1 gene or a 1:1 ortholog thereof." [PRO:WCB] synonym: "B-cell differentiation antigen Ly-44" EXACT [] synonym: "B-cell surface antigen CD20" EXACT [] synonym: "B-lymphocyte antigen CD20" EXACT [] synonym: "B-lymphocyte surface antigen B1" EXACT [] synonym: "Bp35" EXACT [] synonym: "leukocyte surface antigen Leu-16" EXACT [] synonym: "lymphocyte antigen 44" EXACT [] xref: IUPHARobj:2628 xref: PIRSF:PIRSF001995 is_a: PR:000000001 ! protein [Term] id: PR:000001327 name: cadherin namespace: protein def: "A protein that has a core domain structure of signal sequence, propeptide, five Cadherin domains (Pfam:PF00028), a transmembrane region, and a Cadherin cytoplasmic region (Pfam:PF01049). Cadherins function as adhesion molecules that mediate Ca2+-dependent cell-cell adhesion in solid tissues." [PRO:WCB] xref: PIRSF:PIRSF002504 is_a: PR:000000001 ! protein [Term] id: PR:000001444 name: cadherin-5 namespace: protein def: "A cadherin that is a translation product of the human CDH5 gene or a 1:1 ortholog thereof." [PRO:WCB] synonym: "7B4 antigen" EXACT [] synonym: "CD144" EXACT [] synonym: "vascular endothelial cadherin" EXACT [] synonym: "VE-cadherin" EXACT [] is_a: PR:000001327 ! cadherin [Term] id: PR:000001839 name: T-cell surface glycoprotein CD5 namespace: protein def: "A protein that is a translation product of the human CD5 gene or a 1:1 ortholog thereof." [PRO:WCB] synonym: "ly-1" EXACT [] synonym: "lymphocyte antigen 1" EXACT [] synonym: "lymphocyte antigen T1/Leu-1" EXACT [] synonym: "Lyt-1" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:000001869 name: interleukin-7 receptor subunit alpha namespace: protein def: "A protein that is a translation product of the human IL7R gene or a 1:1 ortholog thereof." [PRO:WCB] synonym: "CD127" EXACT [] synonym: "CDw127" EXACT [] synonym: "IL-7 receptor subunit alpha" EXACT [] synonym: "IL-7R subunit alpha" EXACT [] synonym: "IL-7R-alpha" EXACT [] synonym: "IL-7RA" EXACT [] xref: IUPHARobj:1698 xref: PIRSF:PIRSF001960 is_a: PR:000000001 ! protein [Term] id: PR:000001889 name: CD14 molecule namespace: protein def: "A protein that is a translation product of the human CD14 gene or a 1:1 ortholog thereof." [PRO:WCB] synonym: "monocyte differentiation antigen CD14" EXACT [] synonym: "myeloid cell-specific leucine-rich glycoprotein" EXACT [] xref: PIRSF:PIRSF002017 is_a: PR:000000001 ! protein [Term] id: PR:000001945 name: transferrin receptor protein 1 namespace: protein def: "A protein that is a translation product of the human TFRC gene or a 1:1 ortholog thereof." [PRO:WCB] synonym: "CD71" EXACT [] synonym: "T9" EXACT [] synonym: "TfR" EXACT [] synonym: "TfR1" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:000001971 name: vascular endothelial growth factor receptor namespace: protein def: "A protein with core architecture consisting of a signal sequence, followed by 7 Ig-like domains (Pfam:PF00047, Pfam:PF07679, or Pfam:PF07686), a transmembrane region, and a cytoplasmic Protein tyrosine kinase domain." [PRO:WCB] xref: PIRSF:PIRSF038502 is_a: PR:000000001 ! protein [Term] id: PR:000002112 name: vascular endothelial growth factor receptor 2 namespace: protein def: "A vascular endothelial growth factor receptor that is a translation product of the human KDR gene or a 1:1 ortholog thereof." [PRO:WCB] synonym: "CD309" EXACT [] synonym: "fetal liver kinase 1" EXACT [] synonym: "FLK-1" EXACT [] synonym: "kinase insert domain receptor" EXACT [] synonym: "kinase NYK" EXACT [] synonym: "protein-tyrosine kinase receptor flk-1" EXACT [] synonym: "VEGFR-2" EXACT [] xref: IUPHARobj:1813 is_a: PR:000001971 ! vascular endothelial growth factor receptor [Term] id: PR:000002976 name: Ly-6-like protein namespace: protein def: "A protein that is the translation product of any of the LY6 genes (LY6A-LY6I)." [PRO:CNA] xref: PIRSF:PIRSF002021 is_a: PR:000000001 ! protein [Term] id: PR:000002978 name: lymphocyte antigen 6G namespace: protein def: "An Ly-6-like protein that is a translation product of the mouse Ly6g gene or a 1:1 ortholog thereof." [PRO:CNA] synonym: "Ly-6G" EXACT [] synonym: "Ly-6G.1" EXACT [] is_a: PR:000002976 ! Ly-6-like protein [Term] id: PR:000002981 name: lymphocyte antigen 76 (mouse) namespace: protein def: "A protein that is a translation product of the Ly76 gene in mouse." [PMID:10848813, PRO:DAN] synonym: "ter-119" EXACT [] synonym: "ter119" EXACT [] is_a: PR:000029032 ! Mus musculus protein [Term] id: PR:000007499 name: fibroblast growth factor 8 namespace: protein def: "A protein that is a translation product of the human FGF8 gene or a 1:1 ortholog thereof." [PRO:DNx] synonym: "androgen-induced growth factor" EXACT [] synonym: "FGF-8" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:000009054 name: insulin gene translation product namespace: protein def: "An insulin family protein that is a translation product of the human INS gene or a 1:1 ortholog thereof." [PRO:DNx] is_a: PR:000045358 ! insulin family protein [Term] id: PR:000014841 name: sonic hedgehog protein namespace: protein def: "A protein that is a translation product of the human SHH gene or a 1:1 ortholog thereof." [PRO:DNx] synonym: "HHG-1" EXACT [] synonym: "Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains" EXACT [] synonym: "ShhNC" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:000016043 name: T-cell acute lymphocytic leukemia protein 1 namespace: protein def: "A protein that is a translation product of the human TAL1 gene or a 1:1 ortholog thereof." [PRO:DNx] synonym: "bHLHa17" EXACT [] synonym: "class A basic helix-loop-helix protein 17" EXACT [] synonym: "stem cell protein" EXACT [] synonym: "T-cell leukemia/lymphoma protein 5" EXACT [] synonym: "TAL-1" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:000018263 name: amino acid chain namespace: protein def: "A molecule that consists of amino acid residues (unmodified amino-acid residues and/or modified amino-acid residues) linked by peptide bonds or derivatives of such bonds." [PRO:DAN, PRO:JSG] is_a: CHEBI:50047 ! organic amino compound is_a: COB:0000013 ! molecule relationship: has_constituent_monomer CHEBI:33708 ! amino-acid residue relationship: has_constituent_monomer CHEBI:33708 {minCardinality="2"} ! amino-acid residue relationship: RO:0020337 CHEBI:33708 ! has_constituent_monomer amino-acid residue relationship: RO:0020337 CHEBI:33708 {minCardinality="2"} ! has_constituent_monomer amino-acid residue [Term] id: PR:000025796 name: integrin alpha namespace: protein def: "A protein that is composed of a long N-terminal extracellular domain, a transmembrane domain and a short cytoplasmic C-terminal domain. The N-terminal domain contains beta-propeller repeats (interrupted by an A domain in a subset of integrins alpha), while the C-terminal domain contains a GFFxR motif." [PMID:19693543] is_a: PR:000000001 ! protein [Term] id: PR:000029032 name: Mus musculus protein namespace: protein def: "A protein that is encoded in the genome of Mus musculus." [PRO:DAN] is_a: PR:000036194 ! eukaryotic protein intersection_of: PR:000000001 ! protein intersection_of: RO:0002160 NCBITaxon:10090 ! only in taxon Mus musculus relationship: RO:0002160 NCBITaxon:10090 ! only in taxon Mus musculus [Term] id: PR:000029060 name: Drosophila melanogaster protein namespace: protein def: "A protein that is encoded in the genome of Drosophila melanogaster." [PRO:DAN] is_a: PR:000036194 ! eukaryotic protein intersection_of: PR:000000001 ! protein intersection_of: RO:0002160 NCBITaxon:7227 ! only in taxon Drosophila melanogaster relationship: RO:0002160 NCBITaxon:7227 ! only in taxon Drosophila melanogaster [Term] id: PR:000029067 name: Homo sapiens protein namespace: protein def: "A protein that is encoded in the genome of Homo sapiens." [PRO:DAN] is_a: PR:000036194 ! eukaryotic protein intersection_of: PR:000000001 ! protein intersection_of: RO:0002160 NCBITaxon:9606 ! only in taxon Homo sapiens relationship: RO:0002160 NCBITaxon:9606 ! only in taxon Homo sapiens [Term] id: PR:000036194 name: eukaryotic protein namespace: protein def: "A protein that is encoded in the genome of some Eukaryota." [PRO:DAN] synonym: "Eukaryota protein" EXACT [PRO:DAN] is_a: PR:000000001 ! protein intersection_of: PR:000000001 ! protein intersection_of: RO:0002160 NCBITaxon:2759 ! only in taxon Eukaryota relationship: RO:0002160 NCBITaxon:2759 ! only in taxon Eukaryota [Term] id: PR:000045358 name: insulin family protein namespace: protein def: "A protein that is a translation product of a gene that encodes a standalone Insulin (Pfam:PF00049) domain preceded by a signal peptide." [PRO:DAN] is_a: PR:000000001 ! protein [Term] id: PR:000050567 name: protein-containing material entity namespace: protein def: "A material entity that minimally consists of a protein." [PRO:DAN] is_a: BFO:0000040 ! material entity intersection_of: BFO:0000040 ! material entity intersection_of: BFO:0000051 PR:000000001 ! has part protein relationship: BFO:0000051 PR:000000001 ! has part protein [Term] id: PR:P01308 name: insulin gene translation product (human) namespace: protein def: "An insulin gene translation product that is encoded in the genome of human." [PRO:DAN, UniProtKB:P01308] xref: UniProtKB:P01308 is_a: PR:000009054 ! insulin gene translation product is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000009054 ! insulin gene translation product intersection_of: RO:0002160 NCBITaxon:9606 ! only in taxon Homo sapiens [Term] id: PR:P01730 name: T-cell surface glycoprotein CD4 (human) namespace: protein def: "A CD4 molecule that is encoded in the genome of human." [PRO:DNx, UniProtKB:P01730] synonym: "T-cell surface antigen T4/Leu-3 (human)" EXACT [UniProtKB:P01730] xref: UniProtKB:P01730 is_a: PR:000001004 ! CD4 molecule is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000001004 ! CD4 molecule intersection_of: RO:0002160 NCBITaxon:9606 ! only in taxon Homo sapiens [Term] id: PR:P01731 name: T-cell surface glycoprotein CD8 alpha chain (mouse) namespace: protein def: "A T-cell surface glycoprotein CD8 alpha chain that is encoded in the genome of mouse." [OMA:P01731, PRO:DNx] synonym: "CD8a (mouse)" EXACT [UniProtKB:P01731] synonym: "T-cell surface glycoprotein Lyt-2 (mouse)" EXACT [UniProtKB:P01731] xref: UniProtKB:P01731 is_a: PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain intersection_of: RO:0002160 NCBITaxon:10090 ! only in taxon Mus musculus [Term] id: PR:P01732 name: T-cell surface glycoprotein CD8 alpha chain (human) namespace: protein def: "A T-cell surface glycoprotein CD8 alpha chain that is encoded in the genome of human." [PRO:CNA, UniProtKB:P01732] synonym: "CD8a (human)" EXACT [UniProtKB:P01732] synonym: "T-lymphocyte differentiation antigen T8/Leu-2 (human)" EXACT [UniProtKB:P01732] xref: UniProtKB:P01732 is_a: PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain intersection_of: RO:0002160 NCBITaxon:9606 ! only in taxon Homo sapiens [Term] id: PR:P02786 name: transferrin receptor protein 1 (human) namespace: protein def: "A transferrin receptor protein 1 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P02786] synonym: "CD71 (human)" EXACT [UniProtKB:P02786] synonym: "T9 (human)" EXACT [UniProtKB:P02786] synonym: "TfR (human)" EXACT [UniProtKB:P02786] synonym: "TfR1 (human)" EXACT [UniProtKB:P02786] synonym: "Trfr (human)" EXACT [UniProtKB:P02786] xref: Reactome:R-HSA-434196 "PR:P02786 located_in GO:0030659" xref: Reactome:R-HSA-434330 "PR:P02786 located_in GO:0000139" xref: Reactome:R-HSA-8869124 "PR:P02786 located_in GO:0030665" xref: Reactome:R-HSA-8961829 "PR:P02786 located_in GO:0010008" xref: Reactome:R-HSA-917983 "PR:P02786 located_in GO:0005886" xref: UniProtKB:P02786 is_a: PR:000001945 ! transferrin receptor protein 1 is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000001945 ! transferrin receptor protein 1 intersection_of: RO:0002160 NCBITaxon:9606 ! only in taxon Homo sapiens [Term] id: PR:P05555 name: integrin alpha-M (mouse) namespace: protein def: "An integrin alpha-M that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:P05555] synonym: "CD11 antigen-like family member B (mouse)" EXACT [UniProtKB:P05555] synonym: "CD11b (mouse)" EXACT [UniProtKB:P05555] synonym: "cell surface glycoprotein MAC-1 subunit alpha (mouse)" EXACT [UniProtKB:P05555] synonym: "CR-3 alpha chain (mouse)" EXACT [UniProtKB:P05555] synonym: "leukocyte adhesion receptor MO1 (mouse)" EXACT [UniProtKB:P05555] xref: UniProtKB:P05555 is_a: PR:000001012 ! integrin alpha-M is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000001012 ! integrin alpha-M intersection_of: RO:0002160 NCBITaxon:10090 ! only in taxon Mus musculus [Term] id: PR:P06127 name: T-cell surface glycoprotein CD5 (human) namespace: protein def: "A T-cell surface glycoprotein CD5 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P06127] synonym: "lymphocyte antigen T1/Leu-1 (human)" EXACT [UniProtKB:P06127] xref: UniProtKB:P06127 is_a: PR:000001839 ! T-cell surface glycoprotein CD5 is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000001839 ! T-cell surface glycoprotein CD5 intersection_of: RO:0002160 NCBITaxon:9606 ! only in taxon Homo sapiens [Term] id: PR:P06332 name: T-cell surface glycoprotein CD4 (mouse) namespace: protein def: "A CD4 molecule that is encoded in the genome of mouse." [OMA:P06332, PRO:DNx] synonym: "CD4 (mouse)" EXACT [UniProtKB:P06332] synonym: "T-cell differentiation antigen L3T4 (mouse)" EXACT [UniProtKB:P06332] synonym: "T-cell surface antigen T4/Leu-3 (mouse)" EXACT [UniProtKB:P06332] xref: UniProtKB:P06332 is_a: PR:000001004 ! CD4 molecule is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000001004 ! CD4 molecule intersection_of: RO:0002160 NCBITaxon:10090 ! only in taxon Mus musculus [Term] id: PR:P06729 name: T-cell surface antigen CD2 (human) namespace: protein def: "A CD2 molecule that is encoded in the genome of human." [PRO:CNA, UniProtKB:P06729] synonym: "erythrocyte receptor (human)" EXACT [UniProtKB:P06729] synonym: "LFA-2 (human)" EXACT [UniProtKB:P06729] synonym: "LFA-3 receptor (human)" EXACT [UniProtKB:P06729] synonym: "rosette receptor (human)" EXACT [UniProtKB:P06729] synonym: "T-cell surface antigen T11/Leu-5 (human)" EXACT [UniProtKB:P06729] xref: UniProtKB:P06729 is_a: PR:000001083 ! CD2 molecule is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000001083 ! CD2 molecule intersection_of: RO:0002160 NCBITaxon:9606 ! only in taxon Homo sapiens [Term] id: PR:P07766 name: T-cell surface glycoprotein CD3 epsilon chain (human) namespace: protein def: "A CD3 epsilon that is encoded in the genome of human." [PRO:CNA, UniProtKB:P07766] synonym: "CD3e (human)" EXACT [UniProtKB:P07766] synonym: "T-cell surface antigen T3/Leu-4 epsilon chain (human)" EXACT [UniProtKB:P07766] xref: UniProtKB:P07766 is_a: PR:000001020 ! CD3 epsilon is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000001020 ! CD3 epsilon intersection_of: RO:0002160 NCBITaxon:9606 ! only in taxon Homo sapiens [Term] id: PR:P08571 name: monocyte differentiation antigen CD14 (human) namespace: protein def: "A CD14 molecule that is encoded in the genome of human." [PRO:WCB, UniProtKB:P08571] synonym: "myeloid cell-specific leucine-rich glycoprotein (human)" EXACT [UniProtKB:P08571] xref: UniProtKB:P08571 is_a: PR:000001889 ! CD14 molecule is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000001889 ! CD14 molecule intersection_of: RO:0002160 NCBITaxon:9606 ! only in taxon Homo sapiens [Term] id: PR:P08920 name: T-cell surface antigen CD2 (mouse) namespace: protein def: "A CD2 molecule that is encoded in the genome of mouse." [OMA:P08920, PRO:DNx] synonym: "CD2 (mouse)" EXACT [UniProtKB:P08920] synonym: "LFA-2 (mouse)" EXACT [UniProtKB:P08920] synonym: "LFA-3 receptor (mouse)" EXACT [UniProtKB:P08920] synonym: "lymphocyte antigen 37 (mouse)" EXACT [UniProtKB:P08920] synonym: "T-cell surface antigen T11/Leu-5 (mouse)" EXACT [UniProtKB:P08920] xref: UniProtKB:P08920 is_a: PR:000001083 ! CD2 molecule is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000001083 ! CD2 molecule intersection_of: RO:0002160 NCBITaxon:10090 ! only in taxon Mus musculus [Term] id: PR:P10810 name: monocyte differentiation antigen CD14 (mouse) namespace: protein def: "A CD14 molecule that is encoded in the genome of mouse." [OMA:P10810, PRO:WCB] synonym: "CD14 (mouse)" EXACT [UniProtKB:P10810] synonym: "myeloid cell-specific leucine-rich glycoprotein (mouse)" EXACT [UniProtKB:P10810] xref: UniProtKB:P10810 is_a: PR:000001889 ! CD14 molecule is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000001889 ! CD14 molecule intersection_of: RO:0002160 NCBITaxon:10090 ! only in taxon Mus musculus [Term] id: PR:P11215 name: integrin alpha-M (human) namespace: protein def: "An integrin alpha-M that is encoded in the genome of human." [PRO:DNx, UniProtKB:P11215] synonym: "CD11 antigen-like family member B (human)" EXACT [UniProtKB:P11215] synonym: "cell surface glycoprotein MAC-1 subunit alpha (human)" EXACT [UniProtKB:P11215] synonym: "CR-3 alpha chain (human)" EXACT [UniProtKB:P11215] synonym: "leukocyte adhesion receptor MO1 (human)" EXACT [UniProtKB:P11215] synonym: "neutrophil adherence receptor (human)" EXACT [UniProtKB:P11215] xref: UniProtKB:P11215 is_a: PR:000001012 ! integrin alpha-M is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000001012 ! integrin alpha-M intersection_of: RO:0002160 NCBITaxon:9606 ! only in taxon Homo sapiens [Term] id: PR:P11836 name: B-lymphocyte antigen CD20 (human) namespace: protein def: "A membrane-spanning 4-domains subfamily A member 1 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P11836] synonym: "B-lymphocyte surface antigen B1 (human)" EXACT [UniProtKB:P11836] synonym: "Bp35 (human)" EXACT [UniProtKB:P11836] synonym: "leukocyte surface antigen Leu-16 (human)" EXACT [UniProtKB:P11836] synonym: "membrane-spanning 4-domains subfamily A member 1 (human)" EXACT [UniProtKB:P11836] xref: UniProtKB:P11836 is_a: PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 intersection_of: RO:0002160 NCBITaxon:9606 ! only in taxon Homo sapiens [Term] id: PR:P13379 name: T-cell surface glycoprotein CD5 (mouse) namespace: protein def: "A T-cell surface glycoprotein CD5 that is encoded in the genome of mouse." [OMA:P13379, PRO:DNx] synonym: "CD5 (mouse)" EXACT [UniProtKB:P13379] synonym: "lymphocyte antigen 1 (mouse)" EXACT [UniProtKB:P13379] synonym: "Lyt-1 (mouse)" EXACT [UniProtKB:P13379] xref: UniProtKB:P13379 is_a: PR:000001839 ! T-cell surface glycoprotein CD5 is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000001839 ! T-cell surface glycoprotein CD5 intersection_of: RO:0002160 NCBITaxon:10090 ! only in taxon Mus musculus [Term] id: PR:P13591 name: neural cell adhesion molecule 1 (human) namespace: protein def: "A neural cell adhesion molecule 1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P13591] synonym: "CD56 (human)" EXACT [UniProtKB:P13591] synonym: "N-CAM-1 (human)" EXACT [UniProtKB:P13591] synonym: "NCAM-1 (human)" EXACT [UniProtKB:P13591] xref: UniProtKB:P13591 is_a: PR:000001024 ! neural cell adhesion molecule 1 is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000001024 ! neural cell adhesion molecule 1 intersection_of: RO:0002160 NCBITaxon:9606 ! only in taxon Homo sapiens [Term] id: PR:P13595 name: neural cell adhesion molecule 1 (mouse) namespace: protein def: "A neural cell adhesion molecule 1 that is encoded in the genome of mouse." [OMA:P13595, PRO:DNx] synonym: "CD56 (mouse)" EXACT [UniProtKB:P13595] synonym: "N-CAM-1 (mouse)" EXACT [UniProtKB:P13595] synonym: "NCAM-1 (mouse)" EXACT [UniProtKB:P13595] xref: UniProtKB:P13595 is_a: PR:000001024 ! neural cell adhesion molecule 1 is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000001024 ! neural cell adhesion molecule 1 intersection_of: RO:0002160 NCBITaxon:10090 ! only in taxon Mus musculus [Term] id: PR:P15391 name: B-lymphocyte antigen CD19 (human) namespace: protein def: "A CD19 molecule that is encoded in the genome of human." [] synonym: "B-lymphocyte surface antigen B4 (human)" EXACT [UniProtKB:P15391] synonym: "differentiation antigen CD19 (human)" EXACT [UniProtKB:P15391] synonym: "T-cell surface antigen Leu-12 (human)" EXACT [UniProtKB:P15391] xref: UniProtKB:P15391 is_a: PR:000001002 ! CD19 molecule is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000001002 ! CD19 molecule intersection_of: RO:0002160 NCBITaxon:9606 ! only in taxon Homo sapiens [Term] id: PR:P16871 name: interleukin-7 receptor subunit alpha (human) namespace: protein def: "An interleukin-7 receptor subunit alpha that is encoded in the genome of human." [PRO:WCB, UniProtKB:P16871] synonym: "CD127 (human)" EXACT [UniProtKB:P16871] synonym: "CDw127 (human)" EXACT [UniProtKB:P16871] synonym: "IL-7 receptor subunit alpha (human)" EXACT [UniProtKB:P16871] synonym: "IL-7R subunit alpha (human)" EXACT [UniProtKB:P16871] synonym: "IL-7R-alpha (human)" EXACT [UniProtKB:P16871] synonym: "IL-7RA (human)" EXACT [UniProtKB:P16871] xref: UniProtKB:P16871 is_a: PR:000001869 ! interleukin-7 receptor subunit alpha is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000001869 ! interleukin-7 receptor subunit alpha intersection_of: RO:0002160 NCBITaxon:9606 ! only in taxon Homo sapiens [Term] id: PR:P16872 name: interleukin-7 receptor subunit alpha (mouse) namespace: protein def: "An interleukin-7 receptor subunit alpha that is encoded in the genome of mouse." [OMA:P16872, PRO:DNx] synonym: "CD127 (mouse)" EXACT [UniProtKB:P16872] synonym: "IL-7 receptor subunit alpha (mouse)" EXACT [UniProtKB:P16872] synonym: "IL-7R subunit alpha (mouse)" EXACT [UniProtKB:P16872] synonym: "IL-7R-alpha (mouse)" EXACT [UniProtKB:P16872] synonym: "IL-7RA (mouse)" EXACT [UniProtKB:P16872] xref: UniProtKB:P16872 is_a: PR:000001869 ! interleukin-7 receptor subunit alpha is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000001869 ! interleukin-7 receptor subunit alpha intersection_of: RO:0002160 NCBITaxon:10090 ! only in taxon Mus musculus [Term] id: PR:P17542 name: T-cell acute lymphocytic leukemia protein 1 (human) namespace: protein def: "A T-cell acute lymphocytic leukemia protein 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P17542] synonym: "class A basic helix-loop-helix protein 17 (human)" EXACT [UniProtKB:P17542] synonym: "Stem cell protein (human)" EXACT [UniProtKB:P17542] synonym: "T-cell leukemia/lymphoma protein 5 (human)" EXACT [UniProtKB:P17542] synonym: "TAL-1 (human)" EXACT [UniProtKB:P17542] xref: Reactome:R-HSA-8956511 "PR:P17542 located_in GO:0005654" xref: UniProtKB:P17542 is_a: PR:000016043 ! T-cell acute lymphocytic leukemia protein 1 is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000016043 ! T-cell acute lymphocytic leukemia protein 1 intersection_of: RO:0002160 NCBITaxon:9606 ! only in taxon Homo sapiens [Term] id: PR:P19437 name: B-lymphocyte antigen CD20 (mouse) namespace: protein def: "A membrane-spanning 4-domains subfamily A member 1 that is encoded in the genome of mouse." [OMA:P19437, PRO:DNx] synonym: "B-cell differentiation antigen Ly-44 (mouse)" EXACT [UniProtKB:P19437] synonym: "CD20 (mouse)" EXACT [UniProtKB:P19437] synonym: "lymphocyte antigen 44 (mouse)" EXACT [UniProtKB:P19437] synonym: "membrane-spanning 4-domains subfamily A member 1 (mouse)" EXACT [UniProtKB:P19437] xref: UniProtKB:P19437 is_a: PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 intersection_of: RO:0002160 NCBITaxon:10090 ! only in taxon Mus musculus [Term] id: PR:P22091 name: T-cell acute lymphocytic leukemia protein 1 homolog (mouse) namespace: protein def: "A T-cell acute lymphocytic leukemia protein 1 that is encoded in the genome of mouse." [OMA:P22091, PRO:DNx] synonym: "Stem cell protein (mouse)" EXACT [UniProtKB:P22091] synonym: "TAL-1 (mouse)" EXACT [UniProtKB:P22091] xref: UniProtKB:P22091 is_a: PR:000016043 ! T-cell acute lymphocytic leukemia protein 1 is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000016043 ! T-cell acute lymphocytic leukemia protein 1 intersection_of: RO:0002160 NCBITaxon:10090 ! only in taxon Mus musculus [Term] id: PR:P22646 name: T-cell surface glycoprotein CD3 epsilon chain (mouse) namespace: protein def: "A CD3 epsilon that is encoded in the genome of mouse." [OMA:P22646, PRO:DNx] synonym: "CD3e (mouse)" EXACT [UniProtKB:P22646] synonym: "T-cell surface antigen T3/Leu-4 epsilon chain (mouse)" EXACT [UniProtKB:P22646] xref: UniProtKB:P22646 is_a: PR:000001020 ! CD3 epsilon is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000001020 ! CD3 epsilon intersection_of: RO:0002160 NCBITaxon:10090 ! only in taxon Mus musculus [Term] id: PR:P25918 name: B-lymphocyte antigen CD19 (mouse) namespace: protein def: "A CD19 molecule that is encoded in the genome of mouse." [OMA:P25918, PRO:DNx] synonym: "CD19 (mouse)" EXACT [UniProtKB:P25918] synonym: "differentiation antigen CD19 (mouse)" EXACT [UniProtKB:P25918] xref: UniProtKB:P25918 is_a: PR:000001002 ! CD19 molecule is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000001002 ! CD19 molecule intersection_of: RO:0002160 NCBITaxon:10090 ! only in taxon Mus musculus [Term] id: PR:P28906 name: hematopoietic progenitor cell antigen CD34 (human) namespace: protein def: "A CD34 molecule that is encoded in the genome of human." [] xref: UniProtKB:P28906 is_a: PR:000001003 ! CD34 molecule is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000001003 ! CD34 molecule intersection_of: RO:0002160 NCBITaxon:9606 ! only in taxon Homo sapiens [Term] id: PR:P33151 name: cadherin-5 (human) namespace: protein def: "A cadherin-5 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P33151] synonym: "7B4 antigen (human)" EXACT [UniProtKB:P33151] synonym: "CD144 (human)" EXACT [UniProtKB:P33151] synonym: "vascular endothelial cadherin (human)" EXACT [UniProtKB:P33151] synonym: "VE-cadherin (human)" EXACT [UniProtKB:P33151] xref: UniProtKB:P33151 is_a: PR:000001444 ! cadherin-5 is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000001444 ! cadherin-5 intersection_of: RO:0002160 NCBITaxon:9606 ! only in taxon Homo sapiens [Term] id: PR:P35461 name: lymphocyte antigen 6G (mouse) namespace: protein def: "A lymphocyte antigen 6G that is encoded in the genome of mouse." [PRO:CNA, UniProtKB:P35461] synonym: "Ly-6G (mouse)" EXACT [UniProtKB:P35461] synonym: "Ly-6G.1 (mouse)" EXACT [UniProtKB:P35461] xref: UniProtKB:P35461 is_a: PR:000002978 ! lymphocyte antigen 6G is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000002978 ! lymphocyte antigen 6G intersection_of: RO:0002160 NCBITaxon:10090 ! only in taxon Mus musculus [Term] id: PR:P35918 name: vascular endothelial growth factor receptor 2 (mouse) namespace: protein def: "A vascular endothelial growth factor receptor 2 that is encoded in the genome of mouse." [OMA:P35918, PRO:DNx] synonym: "CD309 (mouse)" EXACT [UniProtKB:P35918] synonym: "fetal liver kinase 1 (mouse)" EXACT [UniProtKB:P35918] synonym: "FLK-1 (mouse)" EXACT [UniProtKB:P35918] synonym: "kinase NYK (mouse)" EXACT [UniProtKB:P35918] synonym: "protein-tyrosine kinase receptor flk-1 (mouse)" EXACT [UniProtKB:P35918] synonym: "VEGFR-2 (mouse)" EXACT [UniProtKB:P35918] xref: UniProtKB:P35918 is_a: PR:000002112 ! vascular endothelial growth factor receptor 2 is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000002112 ! vascular endothelial growth factor receptor 2 intersection_of: RO:0002160 NCBITaxon:10090 ! only in taxon Mus musculus [Term] id: PR:P35968 name: vascular endothelial growth factor receptor 2 (human) namespace: protein def: "A vascular endothelial growth factor receptor 2 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P35968] synonym: "CD309 (human)" EXACT [UniProtKB:P35968] synonym: "fetal liver kinase 1 (human)" EXACT [UniProtKB:P35968] synonym: "FLK-1 (human)" EXACT [UniProtKB:P35968] synonym: "kinase insert domain receptor (human)" EXACT [UniProtKB:P35968] synonym: "protein-tyrosine kinase receptor flk-1 (human)" EXACT [UniProtKB:P35968] synonym: "VEGFR-2 (human)" EXACT [UniProtKB:P35968] xref: DTO:03100560 xref: UniProtKB:P35968 is_a: PR:000002112 ! vascular endothelial growth factor receptor 2 is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000002112 ! vascular endothelial growth factor receptor 2 intersection_of: RO:0002160 NCBITaxon:9606 ! only in taxon Homo sapiens [Term] id: PR:P37237 name: fibroblast growth factor 8 (mouse) namespace: protein def: "A fibroblast growth factor 8 that is encoded in the genome of mouse." [OMA:P37237, PRO:DNx] synonym: "AIGF (mouse)" EXACT [UniProtKB:P37237] synonym: "androgen-induced growth factor (mouse)" EXACT [UniProtKB:P37237] synonym: "FGF-8 (mouse)" EXACT [UniProtKB:P37237] xref: UniProtKB:P37237 is_a: PR:000007499 ! fibroblast growth factor 8 is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000007499 ! fibroblast growth factor 8 intersection_of: RO:0002160 NCBITaxon:10090 ! only in taxon Mus musculus [Term] id: PR:P55075 name: fibroblast growth factor 8 (human) namespace: protein def: "A fibroblast growth factor 8 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P55075] synonym: "androgen-induced growth factor (human)" EXACT [UniProtKB:P55075] synonym: "FGF-8 (human)" EXACT [UniProtKB:P55075] xref: UniProtKB:P55075 is_a: PR:000007499 ! fibroblast growth factor 8 is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000007499 ! fibroblast growth factor 8 intersection_of: RO:0002160 NCBITaxon:9606 ! only in taxon Homo sapiens [Term] id: PR:P55284 name: cadherin-5 (mouse) namespace: protein def: "A cadherin-5 that is encoded in the genome of mouse." [OMA:P55284, PRO:DNx] synonym: "CD144 (mouse)" EXACT [UniProtKB:P55284] synonym: "vascular endothelial cadherin (mouse)" EXACT [UniProtKB:P55284] synonym: "VE-cadherin (mouse)" EXACT [UniProtKB:P55284] xref: UniProtKB:P55284 is_a: PR:000001444 ! cadherin-5 is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000001444 ! cadherin-5 intersection_of: RO:0002160 NCBITaxon:10090 ! only in taxon Mus musculus [Term] id: PR:Q15465 name: sonic hedgehog protein (human) namespace: protein def: "A sonic hedgehog protein that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q15465] synonym: "HHG-1 (human)" EXACT [UniProtKB:Q15465] synonym: "Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains (human)" EXACT [UniProtKB:Q15465] synonym: "ShhNC (human)" EXACT [UniProtKB:Q15465] xref: UniProtKB:Q15465 is_a: PR:000014841 ! sonic hedgehog protein is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000014841 ! sonic hedgehog protein intersection_of: RO:0002160 NCBITaxon:9606 ! only in taxon Homo sapiens [Term] id: PR:Q62226 name: sonic hedgehog protein (mouse) namespace: protein def: "A sonic hedgehog protein that is encoded in the genome of mouse." [OMA:Q62226, PRO:DNx] synonym: "HHG-1 (mouse)" EXACT [UniProtKB:Q62226] synonym: "SHH (mouse)" EXACT [UniProtKB:Q62226] synonym: "Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains (mouse)" EXACT [UniProtKB:Q62226] synonym: "ShhNC (mouse)" EXACT [UniProtKB:Q62226] xref: UniProtKB:Q62226 is_a: PR:000014841 ! sonic hedgehog protein is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000014841 ! sonic hedgehog protein intersection_of: RO:0002160 NCBITaxon:10090 ! only in taxon Mus musculus [Term] id: PR:Q62351 name: transferrin receptor protein 1 (mouse) namespace: protein def: "A transferrin receptor protein 1 that is encoded in the genome of mouse." [OMA:Q62351, PRO:DNx] synonym: "CD71 (mouse)" EXACT [UniProtKB:Q62351] synonym: "TfR (mouse)" EXACT [UniProtKB:Q62351] synonym: "TfR1 (mouse)" EXACT [UniProtKB:Q62351] xref: UniProtKB:Q62351 is_a: PR:000001945 ! transferrin receptor protein 1 is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000001945 ! transferrin receptor protein 1 intersection_of: RO:0002160 NCBITaxon:10090 ! only in taxon Mus musculus [Term] id: PR:Q64314 name: hematopoietic progenitor cell antigen CD34 (mouse) namespace: protein def: "A CD34 molecule that is encoded in the genome of mouse." [OMA:Q64314, PRO:DNx] synonym: "CD34 (mouse)" EXACT [UniProtKB:Q64314] xref: UniProtKB:Q64314 is_a: PR:000001003 ! CD34 molecule is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000001003 ! CD34 molecule intersection_of: RO:0002160 NCBITaxon:10090 ! only in taxon Mus musculus [Term] id: PR:Q9V7U0 name: pro-resilin (fruit fly) namespace: protein def: "A protein that is a translation product of the resilin gene in fruit fly." [PRO:DNx, UniProtKB:Q9V7U0] xref: UniProtKB:Q9V7U0 is_a: PR:000029060 ! Drosophila melanogaster protein intersection_of: PR:000000001 ! protein intersection_of: has_gene_template http://flybase.org/reports/FBgn0034157 ! resilin (fruit fly) intersection_of: RO:0002160 NCBITaxon:7227 ! only in taxon Drosophila melanogaster relationship: has_gene_template http://flybase.org/reports/FBgn0034157 ! resilin (fruit fly) [Term] id: RO:0002577 name: system def: "A material entity consisting of multiple components that are causally integrated." [] is_a: BFO:0000040 ! material entity [Term] id: SO:0000110 name: sequence_feature namespace: protein def: "Any extent of continuous biological sequence." [LAMHDI:mb, SO:ke] [Term] id: SO:0000704 name: gene namespace: protein def: "A region (or regions) that includes all of the sequence elements necessary to encode a functional transcript. A gene may include regulatory regions, transcribed regions and/or other functional sequence regions." [SO:immuno_workshop] is_a: SO:0000110 ! sequence_feature [Term] id: SO:0001217 name: protein_coding_gene namespace: protein def: "A gene that codes for an RNA that can be translated into a protein." [] is_a: SO:0000704 ! gene [Term] id: UBERON:0000000 name: processual entity namespace: uberon def: "An occurrent [span:Occurrent] that exists in time by occurring or happening, has temporal parts and always involves and depends on some entity." [span:ProcessualEntity] xref: BFO:0000003 is_a: BFO:0000003 ! occurrent disjoint_from: UBERON:0001062 ! anatomical entity [Term] id: UBERON:0000005 name: chemosensory organ namespace: uberon synonym: "chemosensory sensory organ" EXACT [FBbt:00005157] is_a: UBERON:0000020 ! sense organ intersection_of: UBERON:0000020 ! sense organ intersection_of: RO:0002215 GO:0007606 ! capable of sensory perception of chemical stimulus relationship: BFO:0000050 UBERON:0001016 ! part of nervous system relationship: BFO:0000050 UBERON:0005726 ! part of chemosensory system relationship: RO:0002215 GO:0007606 ! capable of sensory perception of chemical stimulus [Term] id: UBERON:0000006 name: islet of Langerhans namespace: uberon def: "The clusters of hormone-producing cells that are scattered throughout the pancreas." [MA:0000127, MESH:A03.734.414, MP:0005215] synonym: "pancreatic insula" EXACT [] synonym: "pancreatic islet" EXACT [] xref: AAO:0010406 xref: BTO:0000991 xref: CALOHA:TS-0741 xref: EFO:0000856 xref: EMAPA:32927 xref: EV:0100130 xref: FMA:16016 xref: GAID:324 xref: MA:0000127 xref: MAT:0000076 xref: MESH:D007515 xref: MIAA:0000076 xref: NCIT:C12608 xref: UMLS:C0022131 {source="ncithesaurus:Islet_of_Langerhans"} xref: VHOG:0000646 xref: Wikipedia:Islets_of_Langerhans xref: XAO:0000159 is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0034922 ! cell cluster relationship: BFO:0000050 UBERON:0000016 ! part of endocrine pancreas relationship: BFO:0000051 CL:0000168 {source="PMID:16417468"} ! has part insulin secreting cell relationship: BFO:0000051 CL:0000172 {source="PMID:16417468"} ! has part somatostatin secreting cell relationship: BFO:0000051 CL:0000696 {gci_filler="NCBITaxon:117570", gci_relation="BFO:0000050", source="PMID:16417468"} ! has part PP cell relationship: BFO:0000051 CL:0002067 {source="PMID:16417468"} ! has part type A enteroendocrine cell relationship: RO:0002433 UBERON:0000016 ! contributes to morphology of endocrine pancreas property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/9/99/Gray1105.png" xsd:anyURI [Term] id: UBERON:0000009 name: submucosa namespace: uberon def: "A layer of dense irregular connective tissue that lines organs and supports the mucosa, as well as joins the mucosa to the bulk of underlying smooth muscle. [WP,unvetted]." [Wikipedia:Submucosa] synonym: "organ submucosa" EXACT [FMA:85391] synonym: "region of submucosa" EXACT [FMA:85392] synonym: "submucosa of organ" EXACT [FMA:85391] synonym: "submucosa of region of organ" EXACT [FMA:85392] xref: BTO:0002107 xref: FMA:85391 xref: FMA:85392 xref: NCIT:C13167 xref: SCTID:68439008 xref: UMLS:C0225344 {source="ncithesaurus:Submucosa"} xref: Wikipedia:Submucosa is_a: UBERON:0004923 ! organ component layer relationship: BSPO:0001107 UBERON:0000344 ! immediately deep to mucosa relationship: RO:0002160 NCBITaxon:7711 ! only in taxon Chordata relationship: RO:0002473 UBERON:0002384 ! composed primarily of connective tissue property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/4/4e/Ens.png" xsd:anyURI property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/en/thumb/4/4e/Ens.png/200px-Ens.png" xsd:anyURI [Term] id: UBERON:0000010 name: peripheral nervous system namespace: uberon def: "A major division of the nervous system that contains nerves which connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands." [GO:0007422] xref: AAO:0000429 xref: BAMS:PNS xref: BILA:0000081 xref: BIRNLEX:1111 xref: BTO:0001028 xref: CALOHA:TS-0808 xref: EFO:0000891 xref: EHDAA2:0001445 xref: EHDAA:2893 xref: EMAPA:16665 xref: EV:0100335 xref: FMA:9903 xref: GAID:715 xref: MA:0000218 xref: MAT:0000338 xref: MESH:D017933 xref: MIAA:0000338 xref: NCIT:C12465 xref: neuronames:3232 xref: SCTID:362292005 xref: TAO:0000142 xref: UMLS:C0206417 {source="ncithesaurus:Peripheral_Nervous_System", source="BIRNLEX:1111"} xref: UMLS:C1305921 {source="BIRNLEX:1111"} xref: VHOG:0000399 xref: Wikipedia:Peripheral_nervous_system xref: XAO:0000178 xref: ZFA:0000142 is_a: UBERON:0011216 {source="cjm"} ! organ system subdivision relationship: BFO:0000050 UBERON:0001016 ! part of nervous system property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/b/ba/Nervous_system_diagram.png" xsd:anyURI [Term] id: UBERON:0000013 name: sympathetic nervous system namespace: uberon def: "The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter [GO]." [GO:0048485] synonym: "sympathetic nervous system" EXACT [] synonym: "sympathetic part of autonomic division of nervous system" EXACT [] xref: AAO:0010487 xref: BIRNLEX:2516 xref: BTO:0001832 xref: CALOHA:TS-2050 xref: EFO:0000893 xref: EHDAA2:0001971 xref: EHDAA:3769 xref: EMAPA:16985 xref: FMA:9906 xref: GAID:710 xref: MA:0000225 xref: MESH:D013564 xref: MIAA:0000100 xref: NCIT:C12795 xref: SCTID:362484004 xref: TAO:0001576 xref: UMLS:C0039044 {source="BIRNLEX:2516", source="ncithesaurus:Sympathetic_Nervous_System"} xref: UMLS:C1269646 {source="BIRNLEX:2516"} xref: VHOG:0000384 xref: Wikipedia:Sympathetic_nervous_system xref: ZFA:0001576 is_a: UBERON:0011216 {source="cjm"} ! organ system subdivision relationship: BFO:0000050 UBERON:0002410 {source="FMA", source="MA", source="ZFA-modified-from-isa"} ! part of autonomic nervous system relationship: RO:0002433 UBERON:0002410 ! contributes to morphology of autonomic nervous system property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/7/77/Gray838.png" xsd:anyURI [Term] id: UBERON:0000014 name: zone of skin namespace: uberon def: "Any portion of the organ that covers that body and consists of a layer of epidermis and a layer of dermis." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Skin] synonym: "portion of skin" EXACT [] synonym: "region of skin" EXACT [] synonym: "skin" EXACT [MA:0000151] synonym: "skin region" EXACT [] synonym: "skin zone" EXACT [] xref: EHDAA2:0001844 xref: EHDAA:6530 xref: EMAPA:17525 xref: EV:0100152 xref: FMA:86166 xref: GAID:933 xref: MA:0000151 xref: MAT:0000284 xref: MESH:D012867 xref: MIAA:0000284 xref: SCTID:20795001 xref: VHOG:0000860 xref: Wikipedia:Skin is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0010314 ! structure with developmental contribution from neural crest is_a: UBERON:0034944 {source="FMA"} ! zone of organ relationship: BFO:0000050 UBERON:0002097 ! part of skin of body relationship: BFO:0000051 UBERON:0001003 ! has part skin epidermis relationship: BFO:0000051 UBERON:0002067 ! has part dermis property_value: IAO:0000232 "Note the distinction between the entire skin of the body, of which there is only 1 in an organism, and zones of skin, of which there can be many. Examples: skin of knee" xsd:string property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/6/6d/Skin.svg" xsd:anyURI property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/e/e8/HumanSkinDiagram.jpg" xsd:anyURI [Term] id: UBERON:0000015 name: non-material anatomical boundary namespace: uberon def: "A non-material anatomical entity of two dimensions. Anatomical boundaries are contiguous structures." [CARO:0000010] synonym: "anatomical boundary" EXACT [CARO:0000010] xref: AEO:0000192 xref: CARO:0000010 xref: FMA:50705 is_a: UBERON:0000466 {source="CARO"} ! immaterial anatomical entity [Term] id: UBERON:0000016 name: endocrine pancreas namespace: uberon def: "The part of the pancreas that is part of the endocrine system and is made up of islet cells, which produce insulin, glucagon and somatostatin." [GO:GO, http://orcid.org/0000-0002-6601-2165] synonym: "endocrine pancreas" EXACT [] synonym: "pars endocrina pancreatis" EXACT [] xref: BTO:0000650 xref: CALOHA:TS-1302 xref: EFO:0002542 xref: EMAPA:35305 xref: EV:0100129 xref: FMA:16018 xref: MA:0001582 xref: NCIT:C32509 xref: SCTID:361339003 xref: TAO:0001260 xref: VHOG:0000049 xref: Wikipedia:Islets_of_Langerhans xref: ZFA:0001260 is_a: UBERON:0000471 {source="ZFA"} ! compound organ component is_a: UBERON:0004119 ! endoderm-derived structure relationship: BFO:0000050 NCBITaxon:6072 ! part of Eumetazoa relationship: BFO:0000050 UBERON:0000949 {source="AAO", source="FMA", source="XAO"} ! part of endocrine system relationship: BFO:0000050 UBERON:0001264 ! part of pancreas relationship: RO:0002202 UBERON:0003923 ! develops from dorsal pancreatic bud relationship: RO:0002215 GO:0030073 {source="GO"} ! capable of insulin secretion relationship: RO:0002215 GO:0070091 {source="GO"} ! capable of glucagon secretion relationship: RO:0002215 GO:0070253 {source="GO"} ! capable of somatostatin secretion relationship: RO:0002433 UBERON:0001264 ! contributes to morphology of pancreas relationship: RO:0002473 UBERON:0000006 ! composed primarily of islet of Langerhans [Term] id: UBERON:0000017 name: exocrine pancreas namespace: uberon def: "The part of the pancreas that is part of the exocrine system and which produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells [GO]." [GOC:GO, http://orcid.org/0000-0002-6601-2165] synonym: "exocrine pancreas" EXACT [] synonym: "pars exocrina pancreatis" EXACT [] xref: AAO:0010407 xref: BTO:0000434 xref: CALOHA:TS-1241 xref: EMAPA:35328 xref: EV:0100093 xref: FMA:16017 xref: MA:0002415 xref: NCIT:C32546 xref: SCTID:248202004 xref: TAO:0001249 xref: UMLS:C0553695 {source="ncithesaurus:Exocrine_Pancreas"} xref: VHOG:0000048 xref: Wikipedia:Exocrine_component_of_pancreas xref: XAO:0000137 xref: ZFA:0001249 is_a: UBERON:0000409 ! serous gland is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0005177 ! trunk region element relationship: BFO:0000050 UBERON:0001264 ! part of pancreas relationship: BFO:0000051 UBERON:0001263 ! has part pancreatic acinus relationship: BFO:0000051 UBERON:0007329 ! has part pancreatic duct relationship: RO:0002202 UBERON:0003924 ! develops from ventral pancreatic bud relationship: RO:0002216 GO:0007586 ! capable of part of digestion relationship: RO:0002433 UBERON:0001264 ! contributes to morphology of pancreas [Term] id: UBERON:0000018 name: compound eye namespace: uberon def: "A light sensing organ composed of ommatidia." [FB:gg, Wikipedia:Compound_eye] xref: BTO:0001921 xref: HAO:0000217 xref: TGMA:0000024 xref: Wikipedia:Compound_eye is_a: UBERON:0015165 ! multi-unit eye intersection_of: UBERON:0000970 ! eye intersection_of: RO:0002473 UBERON:0000971 ! composed primarily of ommatidium relationship: RO:0002160 NCBITaxon:6656 {source="PMID:21062451"} ! only in taxon Arthropoda relationship: RO:0002473 UBERON:0000971 ! composed primarily of ommatidium [Term] id: UBERON:0000019 name: camera-type eye namespace: uberon def: "An organ of sight that includes the camera-type eyeball and supporting structures such as the lacrimal apparatus, the conjunctiva, the eyelid." [GO:0043010, https://orcid.org/0000-0002-6601-2165] xref: AAO:0010340 xref: BIRNLEX:1169 xref: BTO:0004688 xref: EHDAA2:0000484 xref: EHDAA:936 xref: EMAPA:16198 xref: FMA:54448 xref: MA:0000261 xref: NCIT:C12401 xref: SCTID:181143004 xref: TAO:0000107 xref: UMLS:C0015392 {source="BIRNLEX:1169", source="ncithesaurus:Eye"} xref: UMLS:C1280202 {source="BIRNLEX:1169"} xref: VHOG:0000275 xref: XAO:0000179 xref: ZFA:0000107 is_a: UBERON:0000047 ! simple eye is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0010314 ! structure with developmental contribution from neural crest is_a: UBERON:0015212 ! lateral structure relationship: BFO:0000050 UBERON:0004088 ! part of orbital region relationship: BFO:0000051 UBERON:0000965 ! has part lens of camera-type eye relationship: BFO:0000051 UBERON:0000966 ! has part retina relationship: BSPO:0000126 UBERON:0000033 ! in lateral side of head relationship: RO:0002202 UBERON:0003072 ! develops from optic cup relationship: RO:0002492 UBERON:0000066 ! existence ends during fully formed stage [Term] id: UBERON:0000020 name: sense organ namespace: uberon def: "An organ that is capable of transducing sensory stimulus to the nervous system." [https://github.com/obophenotype/uberon/issues/549, https://orcid.org/0000-0002-6601-2165] synonym: "organ of sense organ system" EXACT [OBOL:accepted] synonym: "organ of sensory organ system" EXACT [OBOL:accepted] synonym: "organ of sensory system" EXACT [OBOL:accepted] synonym: "sense organ system organ" EXACT [OBOL:automatic] synonym: "sensory organ" EXACT [] synonym: "sensory organ system organ" EXACT [OBOL:automatic] synonym: "sensory system organ" EXACT [OBOL:accepted] xref: AEO:0000094 xref: BSA:0000121 xref: BTO:0000202 xref: CALOHA:TS-2043 xref: EHDAA2:0001824 xref: EHDAA:500 xref: EMAPA:35955 xref: GAID:63 xref: HAO:0000930 xref: MA:0000017 xref: MESH:D012679 xref: NCIT:C33224 xref: SCTID:244485009 xref: UMLS:C0935626 {source="ncithesaurus:Organ_of_the_Special_Sense"} xref: VHOG:0001407 xref: WBbt:0006929 is_a: UBERON:0000062 ! organ intersection_of: UBERON:0000062 ! organ intersection_of: RO:0002215 GO:0050906 ! capable of detection of stimulus involved in sensory perception relationship: BFO:0000050 UBERON:0001032 ! part of sensory system relationship: RO:0002215 GO:0050906 ! capable of detection of stimulus involved in sensory perception property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/c/c0/Gray722.png" xsd:anyURI property_value: x_1.1:contributor https://github.com/cmungall [Term] id: UBERON:0000025 name: tube namespace: uberon def: "Any hollow cylindrical anatomical structure containing a lumen through which substances are transported." [http://orcid.org/0000-0002-6601-2165] synonym: "anatomical tube" EXACT [] xref: galen:Tube is_a: UBERON:0004111 ! anatomical conduit intersection_of: UBERON:0004111 ! anatomical conduit intersection_of: RO:0000086 PATO:0002299 ! has quality tubular relationship: BFO:0000051 UBERON:0013522 ! has part subdivision of tube relationship: RO:0000086 PATO:0002299 ! has quality tubular property_value: IAO:0000232 "not every anatomical conduit is a tube - for example, a bone foramen is an opening in the bone, and there is no distinct separate tube structure. Tubes may transport large mixed objects (for example, a bolus of food in the digestive tube) or they may transport the secretions of a single gland (for example, gland ducts)" xsd:string [Term] id: UBERON:0000026 name: appendage namespace: uberon def: "Major subdivision of an organism that protrudes from the body[DOS, CARO]." [CARO:DOS] xref: AEO:0000193 xref: BILA:0000018 xref: BTO:0001492 xref: CARO:0010003 xref: EFO:0000799 xref: EHDAA2:0003193 xref: EMAPA:37283 {source="MA:th"} xref: EV:0100155 xref: HAO:0000144 xref: MAT:0000023 xref: MESH:D005121 xref: MIAA:0000023 xref: NCIT:C61460 xref: UMLS:C0598782 {source="ncithesaurus:Appendage"} xref: VSAO:0000075 xref: Wikipedia:Appendage xref: XAO:0000218 is_a: UBERON:0000475 ! organism subdivision relationship: RO:0002160 NCBITaxon:6072 ! only in taxon Eumetazoa [Term] id: UBERON:0000030 name: lamina propria namespace: uberon def: "A thin layer of loose connective tissue which lies beneath the epithelium and together with the epithelium constitutes the mucosa[WP]. The lamina propria contains capillaries and a central lacteal (lymph vessel) in the small intestine, as well as lymphoid tissue. Lamina propria also contains glands with the ducts opening on to the mucosal epithelium, that secrete mucus and serous secretions." [Wikipedia:Lamina_propria] synonym: "lamina propria mucosa" EXACT [] synonym: "lamina propria mucosae" EXACT [] xref: BTO:0002330 xref: FMA:62517 xref: NCIT:C32918 xref: SCTID:298225002 xref: UMLS:C1179187 {source="ncithesaurus:Lamina_Propria"} xref: Wikipedia:Lamina_propria is_a: UBERON:0004923 ! organ component layer relationship: BFO:0000050 UBERON:0000344 ! part of mucosa relationship: BSPO:0001107 UBERON:0000483 ! immediately deep to epithelium relationship: RO:0002473 UBERON:0011825 ! composed primarily of loose connective tissue property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/f/fb/GI_Organization.svg" xsd:anyURI [Term] id: UBERON:0000031 name: lamina propria of trachea namespace: uberon def: "A lamina propria that is part of a respiratory airway." [OBOL:automatic] synonym: "lamina propria mucosa of trachea" EXACT [OBOL:automatic] synonym: "lamina propria mucosa of windpipe" EXACT [OBOL:automatic] synonym: "lamina propria mucosae of trachea" EXACT [OBOL:automatic] synonym: "lamina propria mucosae of windpipe" EXACT [OBOL:automatic] synonym: "lamina propria of windpipe" EXACT [OBOL:automatic] synonym: "trachea lamina propria" EXACT [] synonym: "trachea lamina propria mucosa" EXACT [OBOL:automatic] synonym: "trachea lamina propria mucosae" EXACT [OBOL:automatic] synonym: "tracheal lamina propria" EXACT [] synonym: "windpipe lamina propria" EXACT [OBOL:automatic] synonym: "windpipe lamina propria mucosa" EXACT [OBOL:automatic] synonym: "windpipe lamina propria mucosae" EXACT [OBOL:automatic] xref: EMAPA:35877 xref: FMA:265157 xref: MA:0001858 xref: NCIT:C49305 xref: UMLS:C1710457 {source="ncithesaurus:Trachea_Lamina_Propria"} is_a: UBERON:0004779 ! respiratory system lamina propria intersection_of: UBERON:0000030 ! lamina propria intersection_of: BFO:0000050 UBERON:0001005 ! part of respiratory airway relationship: BFO:0000050 UBERON:0000379 ! part of tracheal mucosa [Term] id: UBERON:0000033 name: head namespace: uberon def: "The head is the anterior-most division of the body [GO]." [GO:0060322, Wikipedia:Head] synonym: "head (volume)" EXACT [FMA:7154] xref: AAO:0010335 xref: AEO:0000106 xref: BILA:0000115 xref: BIRNLEX:1230 xref: BTO:0000282 xref: CALOHA:TS-0436 xref: EFO:0000964 xref: EHDAA2:0003106 xref: EMAPA:31858 xref: FMA:7154 xref: GAID:61 xref: galen:Head xref: HAO:0000397 xref: MA:0000023 xref: MAT:0000294 xref: MESH:D006257 xref: MIAA:0000294 xref: NCIT:C12419 xref: SCTID:302548004 xref: SPD:0000016 xref: TAO:0001114 xref: TGMA:0000002 xref: UMLS:C0018670 {source="ncithesaurus:Head", source="BIRNLEX:1230"} xref: VHOG:0001644 xref: WBbt:0005739 xref: Wikipedia:Head xref: XAO:0003024 xref: ZFA:0001114 is_a: UBERON:0011676 ! subdivision of organism along main body axis relationship: BFO:0000050 UBERON:0007811 ! part of craniocervical region relationship: RO:0002160 NCBITaxon:33213 ! only in taxon Bilateria relationship: RO:0002551 UBERON:0003129 {gci_filler="NCBITaxon:7776", gci_relation="BFO:0000050"} ! has skeleton skull [Term] id: UBERON:0000042 name: serous membrane namespace: uberon def: "Multi-tissue structure that is comprised of a secretory epithelial layer (mesothelium) and a connective tissue layer." [https://github.com/obophenotype/uberon/issues/86, Wikipedia:Serous_membrane] synonym: "wall of serous sac" EXACT [FMA:9581] xref: FMA:9581 xref: GAID:19 xref: MESH:D012704 xref: NCIT:C13169 xref: SCTID:362878009 xref: TAO:0005425 xref: UMLS:C0036760 {source="ncithesaurus:Serosa"} xref: Wikipedia:Serous_membrane xref: ZFA:0005425 is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000481 ! multi-tissue structure is_a: UBERON:0004120 ! mesoderm-derived structure relationship: BFO:0000050 NCBITaxon:6072 ! part of Eumetazoa relationship: BFO:0000050 UBERON:0000060 ! part of anatomical wall relationship: BFO:0000051 UBERON:0001136 ! has part mesothelium relationship: BFO:0000051 UBERON:0002384 ! has part connective tissue property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/4/4e/Ens.png" xsd:anyURI property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/en/thumb/4/4e/Ens.png/200px-Ens.png" xsd:anyURI property_value: x_1.1:contributor https://github.com/cmungall [Term] id: UBERON:0000043 name: tendon namespace: uberon def: "Dense regular connective tissue that connects muscle to bone[VSAO]." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, VSAO:0000073, Wikipedia:Tendon] xref: AEO:0000091 xref: BTO:0001356 xref: CALOHA:TS-1021 xref: EHDAA2:0003091 xref: EMAPA:35854 xref: EV:0100149 xref: FMA:9721 xref: GAID:276 xref: galen:Tendon xref: MA:0000115 xref: MESH:D013710 xref: NCIT:C13045 xref: SCTID:256667004 xref: UMLS:C0039508 {source="ncithesaurus:Tendon"} xref: VHOG:0001286 xref: VSAO:0000073 xref: Wikipedia:Tendon xref: XAO:0000173 xref: ZFA:0005647 is_a: UBERON:0007846 {source="VSAO"} ! dense regular connective tissue relationship: BFO:0000050 UBERON:0002204 {source="OG"} ! part of musculoskeletal system relationship: BFO:0000051 CL:0000327 {source="AEO"} ! has part extracellular matrix secreting cell relationship: RO:0002160 NCBITaxon:7742 ! only in taxon Vertebrata relationship: RO:0002176 UBERON:0001474 ! connects bone element relationship: RO:0002176 UBERON:0001630 ! connects muscle organ property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/3/3c/Achilles-tendon.jpg" xsd:anyURI [Term] id: UBERON:0000045 name: ganglion namespace: uberon def: "A biological tissue mass, most commonly a mass of nerve cell bodies." [https://github.com/obophenotype/uberon/issues/300, Wikipedia:Ganglion] xref: AAO:0010426 xref: AEO:0000135 xref: BAMS:G xref: BTO:0000497 xref: CALOHA:TS-0397 xref: EFO:0000899 xref: EHDAA2:0003135 xref: EHDAA:2897 xref: EHDAA:4662 xref: EHDAA:5621 xref: EHDAA:918 xref: EMAPA:32846 xref: EV:0100372 xref: FMA:5884 xref: MA:0002406 xref: MAT:0000207 xref: MAT:0000343 xref: MESH:D005724 xref: MIAA:0000207 xref: MIAA:0000343 xref: NCIT:C12719 xref: NLXANAT:100302 xref: TAO:0000190 xref: TGMA:0001016 xref: UMLS:C0017067 {source="ncithesaurus:Ganglion"} xref: VHOG:0000156 xref: WBbt:0005189 xref: Wikipedia:Ganglion xref: XAO:0000209 xref: ZFA:0000190 is_a: UBERON:0000061 {source="https://github.com/obophenotype/uberon/issues/2495#issuecomment-1187364719"} ! anatomical structure relationship: BFO:0000050 UBERON:0001016 ! part of nervous system relationship: RO:0002473 UBERON:0003714 {source="EHDAA2"} ! composed primarily of neural tissue relationship: RO:0002495 UBERON:0003869 {source="Bgee:AN"} ! immediate transformation of presumptive ganglion property_value: x_1.1:contributor https://github.com/cmungall [Term] id: UBERON:0000046 name: stemma namespace: uberon def: "Eye-spots which may be set into a pit to reduce the angles of light that enters and affects the eyespot, to allow the organism to deduce the angle of incoming light." [Wikipedia:Eye#Pit_eyes, Wikipedia:Stemma] synonym: "pit eye" EXACT [Wikipedia:Eye#Pit_eyes] xref: Wikipedia:Stemma is_a: UBERON:0000047 ! simple eye property_value: AISM:0000171 "Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Stemmata are specific lateral eyes (the term “lateral ocelli” is inappropriate) of larvae of most groups of Holometabola. They are replaced by the adult compound eyes during the metamorphosis. The number ranges between seven and one and they are absent in different groups. Structurally, they resemble ommatidia and are suitable to perceive movements, directions and distances.\"" xsd:string [Term] id: UBERON:0000047 name: simple eye namespace: uberon def: "An eye with one concave chamber. Note that 'simple' does not imply a reduced level of complexity or acuity." [Wikipedia:Eye#Simple_eyes] xref: TGMA:0000729 xref: Wikipedia:Eye#Simple_eyes is_a: UBERON:0000970 ! eye [Term] id: UBERON:0000055 name: vessel namespace: uberon def: "A tubular structure that contains, conveys body fluid, such as blood or lymph." [https://orcid.org/0000-0002-6601-2165] is_a: UBERON:0004111 ! anatomical conduit relationship: channel_for UBERON:0006314 ! bodily fluid [Term] id: UBERON:0000056 name: ureter namespace: uberon def: "Muscular duct that propels urine from the kidneys to the urinary bladder, or related organs." [GO:0090189, Wikipedia:Ureter] xref: AAO:0010254 xref: BTO:0001409 xref: CALOHA:TS-1084 xref: EFO:0000930 xref: EHDAA2:0002139 xref: EHDAA:9341 xref: EMAPA:17950 xref: EV:0100097 xref: FMA:9704 xref: GAID:438 xref: galen:Ureter xref: MA:0000378 xref: MAT:0000120 xref: MESH:D014513 xref: MIAA:0000120 xref: NCIT:C12416 xref: SCTID:302511008 xref: UMLS:C0041951 {source="ncithesaurus:Ureter"} xref: VHOG:0000605 xref: Wikipedia:Ureter xref: XAO:0000144 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005179 ! pelvic region element is_a: UBERON:0006555 ! excretory tube is_a: UBERON:0015212 ! lateral structure relationship: BFO:0000050 UBERON:0036295 ! part of renal pelvis/ureter relationship: BSPO:0000126 UBERON:0000468 ! in lateral side of multicellular organism relationship: channel_for UBERON:0001088 ! urine relationship: channels_from UBERON:0001224 ! renal pelvis relationship: channels_into UBERON:0001255 ! urinary bladder relationship: RO:0002202 UBERON:0005081 {source="GO"} ! develops from ureter ureteric bud property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/3/30/Urinary_system.svg" xsd:anyURI [Term] id: UBERON:0000057 name: urethra namespace: uberon def: "The fibromuscular tubular canal through which urine is discharged from the bladder to the exterior via the external urinary meatus; in males, the urethra is joined by the ejaculatory ducts and serves as a passageway for semen during ejaculation, as well as a canal for urine during voiding; in females, the urethra is shorter and emerges above the vaginal opening." [MGI:anna, MP:0000537] xref: BTO:0001426 xref: CALOHA:TS-1132 xref: EFO:0000931 xref: EMAPA:30901 xref: EV:0100099 xref: FMA:19667 xref: GAID:390 xref: galen:Urethra xref: MA:0000379 xref: MAT:0000121 xref: MESH:D014521 xref: MIAA:0000121 xref: NCIT:C12417 xref: SCTID:302513006 xref: UMLS:C0041967 {source="ncithesaurus:Urethra"} xref: VHOG:0001264 xref: Wikipedia:Urethra xref: XAO:0000153 is_a: UBERON:0000062 ! organ is_a: UBERON:0004111 ! anatomical conduit is_a: UBERON:0004120 ! mesoderm-derived structure relationship: BFO:0000050 UBERON:0001556 ! part of lower urinary tract relationship: channel_for UBERON:0001088 ! urine relationship: channels_from UBERON:0001255 ! urinary bladder relationship: RO:0002150 UBERON:0001255 ! continuous with urinary bladder relationship: RO:0002202 UBERON:0000164 ! develops from primitive urogenital sinus relationship: RO:0002202 UBERON:0013241 {source="Wikipedia"} ! develops from embryonic urethral groove relationship: RO:0002216 GO:0060073 ! capable of part of micturition property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/c/cb/Female_anatomy.png" xsd:anyURI [Term] id: UBERON:0000058 name: duct namespace: uberon def: "A tubular structure that transports secreted or excreted substances." [http://orcid.org/0000-0002-6601-2165, http://www.siumed.edu/~dking2/intro/glands.htm#ducts] synonym: "anatomical duct" EXACT [] xref: AAO:0011123 xref: FMA:30320 xref: galen:Duct xref: NCIT:C12948 xref: SCTID:91726008 xref: TAO:0005171 xref: UMLS:C0687028 {source="ncithesaurus:Duct"} xref: Wikipedia:Duct_(anatomy) xref: XAO:0004000 xref: ZFA:0005171 is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000063 ! organ subunit relationship: BFO:0000051 UBERON:0034969 ! has part epithelial layer of duct relationship: RO:0000086 PATO:0002299 ! has quality tubular relationship: RO:0002570 UBERON:0000463 ! conduit for organism substance [Term] id: UBERON:0000059 name: large intestine namespace: uberon def: "A subdivision of the digestive tract that connects the small intestine to the cloaca or anus. Lacks or has few villi[Kardong]." [ISBN:0073040584, Wikipedia:Large_intestine_(anatomy)] xref: AAO:0010396 xref: BTO:0000706 xref: CALOHA:TS-1306 xref: EFO:0000840 xref: EMAPA:19252 xref: EV:0100077 xref: FMA:7201 xref: GAID:306 xref: galen:LargeIntestine xref: MA:0000333 xref: MESH:D007420 xref: MIAA:0000046 xref: NCIT:C12379 xref: SCTID:181254001 xref: UMLS:C0021851 {source="ncithesaurus:Large_Intestine"} xref: VHOG:0000054 xref: Wikipedia:Large_intestine_(anatomy) xref: XAO:0000131 is_a: UBERON:0004921 {source="cjm"} ! subdivision of digestive tract is_a: UBERON:0013765 ! digestive system element relationship: BFO:0000050 UBERON:0000160 ! part of intestine relationship: BFO:0000050 UBERON:0004907 ! part of lower digestive tract relationship: RO:0002160 NCBITaxon:7742 ! only in taxon Vertebrata relationship: RO:0002433 UBERON:0000160 ! contributes to morphology of intestine property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.0/SBU_F_Intestine_Large.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/SBU_F_Intestine_Large.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/SBU_M_Intestine_Large.glb" xsd:anyURI [Term] id: UBERON:0000060 name: anatomical wall namespace: uberon def: "Organ component adjacent to an organ cavity and which consists of a maximal aggregate of organ component layers." [FMA:82482] synonym: "wall of organ" EXACT [FMA:82482] xref: EMAPA:25036 xref: FMA:82482 xref: galen:Wall is_a: UBERON:0000064 ! organ part relationship: BFO:0000051 UBERON:0004923 ! has part organ component layer relationship: RO:0002220 UBERON:0002553 ! adjacent to anatomical cavity [Term] id: UBERON:0000061 name: anatomical structure namespace: uberon def: "Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome." [CARO:0000003] synonym: "biological structure" EXACT [] synonym: "connected biological structure" EXACT [CARO:0000003] xref: AAO:0010825 xref: AEO:0000003 xref: BILA:0000003 xref: CARO:0000003 xref: EHDAA2:0003003 xref: EMAPA:0 xref: FAO:0000001 xref: FMA:305751 xref: FMA:67135 xref: GAID:781 xref: HAO:0000003 xref: http://dbpedia.org/ontology/AnatomicalStructure xref: MA:0003000 xref: MESH:D000825 xref: SCTID:362889002 xref: TAO:0000037 xref: TGMA:0001823 xref: VHOG:0001759 xref: XAO:0003000 xref: ZFA:0000037 is_a: UBERON:0000465 ! material anatomical entity relationship: RO:0002496 UBERON:0000106 {gci_filler="NCBITaxon:33208", gci_relation="RO:0002162"} ! existence starts during or after zygote stage relationship: RO:0002497 UBERON:0000071 ! existence ends during or before death stage [Term] id: UBERON:0000062 name: organ namespace: uberon def: "Anatomical structure that performs a specific function or group of functions [WP]." [Wikipedia:Organ_(anatomy)] xref: BIRNLEX:4 xref: CARO:0020004 xref: EFO:0000634 xref: EMAPA:35949 xref: ENVO:01000162 xref: FMA:67498 xref: MA:0003001 xref: NCIT:C13018 xref: SCTID:272625005 xref: UMLS:C0178784 {source="ncithesaurus:Organ"} xref: WBbt:0003760 xref: Wikipedia:Organ_(anatomy) is_a: UBERON:0010000 ! multicellular anatomical structure disjoint_from: UBERON:0002095 {source="PMID:28192867"} ! mesentery disjoint_from: UBERON:0034921 ! multi organ part structure relationship: BFO:0000050 UBERON:0000467 ! part of anatomical system relationship: RO:0002002 UBERON:0006984 ! has 2D boundary anatomical surface relationship: RO:0002215 GO:0008150 ! capable of biological_process relationship: RO:0002496 UBERON:0000111 {gci_filler="NCBITaxon:6072", gci_relation="RO:0002162"} ! existence starts during or after organogenesis stage [Term] id: UBERON:0000063 name: organ subunit namespace: uberon def: "A part of an organ that constitutes a distinct modular sub-unit. In some cases, the organ may also contain other sub-units of identical or similar types, in other cases this may be a distinct entity." [http://orcid.org/0000-0002-6601-2165] xref: FMA:86140 is_a: UBERON:0000064 ! organ part [Term] id: UBERON:0000064 name: organ part namespace: uberon def: "A multicellular structure that is a part of an organ." [http://orcid.org/0000-0002-6601-2165] synonym: "cardinal organ part" EXACT [FMA:82472] xref: AAO:0011124 xref: BIRNLEX:16 xref: EFO:0000635 xref: FMA:82472 xref: SCTID:113343008 xref: SCTID:91717005 is_a: UBERON:0010000 ! multicellular anatomical structure relationship: BFO:0000050 UBERON:0000062 ! part of organ property_value: IAO:0000232 "currently defined in a very broad sense, may be replaced by more specific classes in the future" xsd:string [Term] id: UBERON:0000065 name: respiratory tract namespace: uberon def: "Anatomical structure that is part of the respiratory system. In mammals consists of upper and lower tracts." [https://orcid.org/0000-0002-6601-2165] xref: EHDAA2:0001606 xref: EHDAA:1568 xref: EHDAA:2219 xref: EMAPA:16737 xref: FMA:265130 xref: SCTID:361110005 xref: VHOG:0000393 is_a: UBERON:0001005 ! respiratory airway is_a: UBERON:0004119 ! endoderm-derived structure relationship: RO:0002202 UBERON:0007026 {source="NCBIBook:NBK10107"} ! develops from presumptive gut relationship: RO:0002202 UBERON:0008947 ! develops from respiratory primordium [Term] id: UBERON:0000066 name: fully formed stage namespace: uberon def: "The stage of development at which the animal is fully formed, including immaturity and maturity. Includes both sexually immature stage, and adult stage." [https://orcid.org/0000-0002-6601-2165] synonym: "fully formed animal stage" EXACT [] synonym: "juvenile-adult stage" EXACT [] xref: BilaDO:0000004 xref: BTO:0001043 xref: EFO:0001272 xref: FBdv:00005369 xref: WBls:0000041 xref: XtroDO:0000084 is_a: UBERON:0000105 ! life cycle stage relationship: BFO:0000050 UBERON:0000092 ! part of post-embryonic stage relationship: BFO:0000062 UBERON:0000111 ! preceded by organogenesis stage relationship: BFO:0000062 UBERON:0004729 {gci_relation="BFO:0000050", gci_filler="NCBITaxon:6239"} ! preceded by nematode larval stage relationship: BFO:0000063 UBERON:0000071 ! precedes death stage [Term] id: UBERON:0000068 name: embryo stage namespace: uberon def: "A life cycle stage that starts with fertilization and ends with the fully formed embryo." [http://orcid.org/0000-0002-6601-2165] synonym: "embryonic stage" EXACT [] xref: BilaDO:0000002 xref: EV:0300001 xref: FBdv:00005289 xref: FMA:72652 xref: HsapDv:0000002 xref: MmusDv:0000002 xref: OGES:000000 xref: OGES:000022 xref: SCTID:296280003 xref: WBls:0000003 xref: WBls:0000092 xref: WBls:0000102 xref: XAO:1000012 is_a: UBERON:0000105 ! life cycle stage disjoint_from: UBERON:0000092 ! post-embryonic stage relationship: BFO:0000063 UBERON:0000066 ! precedes fully formed stage relationship: BFO:0000063 UBERON:0000092 ! precedes post-embryonic stage relationship: RO:0002082 GO:0009790 ! simultaneous with embryo development [Term] id: UBERON:0000069 name: larval stage namespace: uberon def: "A distinct juvenile stage many animals undergo before metamorphosis into adults. Animals with indirect development such as insects, amphibians, or cnidarians typically have a larval phase of their life cycle." [Wikipedia:Larva] synonym: "larva stage" EXACT [] xref: BTO:0000915 xref: BTO:0000954 xref: EFO:0001303 xref: FBdv:00005336 xref: MIAA:0000400 xref: OGES:000008 xref: Wikipedia:Larva xref: ZFS:0000048 is_a: UBERON:0000105 ! life cycle stage relationship: BFO:0000050 UBERON:0000092 ! part of post-embryonic stage relationship: RO:0002082 GO:0002164 ! simultaneous with larval development relationship: RO:0002087 UBERON:0000068 ! immediately preceded by embryo stage property_value: IAO:0000232 "Uberon includes clade-specific subclasses, e.g. nematod larva" xsd:string [Term] id: UBERON:0000070 name: pupal stage namespace: uberon def: "A life cycle stage of holometabolous insects in which the organism is a pupa and starts with the larval-pupal apolysis and ends with pupal-adult apolysis." [https://github.com/obophenotype/uberon/issues/562, Wikipedia:Pupa] synonym: "pupa stage" EXACT [] xref: FBdv:00005349 xref: Wikipedia:Pupa is_a: UBERON:0000105 ! life cycle stage relationship: BFO:0000050 UBERON:0000092 ! part of post-embryonic stage relationship: RO:0002082 GO:0035209 ! simultaneous with pupal development relationship: RO:0002087 UBERON:0000069 ! immediately preceded by larval stage relationship: RO:0002160 NCBITaxon:33392 ! only in taxon Endopterygota property_value: x_1.1:contributor https://github.com/ANiknejad property_value: x_1.1:contributor https://github.com/cmungall property_value: x_1.1:contributor https://github.com/dosumis property_value: x_1.1:contributor https://github.com/fbastian property_value: x_1.1:contributor https://github.com/mmc46 [Term] id: UBERON:0000071 name: death stage namespace: uberon def: "End of the life of an organism." [XAO:0000437] xref: XAO:0000437 xref: XtroDO:0000085 is_a: UBERON:0000105 ! life cycle stage relationship: RO:0002229 UBERON:0000104 ! ends life cycle [Term] id: UBERON:0000072 name: proximo-distal subdivision of respiratory tract namespace: uberon def: "An section of a respiratory tract." [http://orcid.org/0000-0002-6601-2165] xref: EMAPA:16737 xref: FMA:45660 xref: MA:0000434 is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0013522 ! subdivision of tube intersection_of: UBERON:0013522 ! subdivision of tube intersection_of: BFO:0000050 UBERON:0000065 ! part of respiratory tract relationship: BFO:0000050 UBERON:0000065 ! part of respiratory tract [Term] id: UBERON:0000073 name: regional part of nervous system namespace: uberon def: "Any part or collection of parts of the central or peripheral nervous system. Parts may span both CNS and PNS." [BIRNLEX:1157] synonym: "part of nervous system" EXACT [BIRNLEX:1157] xref: BIRNLEX:1157 xref: NCIT:C13040 xref: SCTID:25087005 xref: UMLS:C1518256 {source="ncithesaurus:Nervous_System_Part"} is_a: UBERON:0000481 ! multi-tissue structure intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: BFO:0000050 UBERON:0001016 ! part of nervous system relationship: BFO:0000050 NCBITaxon:6072 ! part of Eumetazoa relationship: BFO:0000050 UBERON:0001016 ! part of nervous system creation_date: 2009-06-18T09:00:04Z [Term] id: UBERON:0000075 name: subdivision of skeletal system namespace: uberon def: "Anatomical cluster consisting of the skeletal elements and articular elements that are part of an individual subdivision of the organism." [https://orcid.org/0000-0002-6601-2165, UBERONREF:0000003] synonym: "skeletal system subdivision" EXACT [FMA:85544] xref: FMA:85544 xref: galen:ComplexSkeletalStructure xref: NCIT:C34076 xref: SCTID:118966000 xref: UMLS:C1519343 {source="ncithesaurus:Skeletal_System_Part"} is_a: UBERON:0011216 {source="cjm"} ! organ system subdivision relationship: BFO:0000050 UBERON:0001434 ! part of skeletal system relationship: RO:0002160 NCBITaxon:7711 ! only in taxon Chordata relationship: RO:0002473 UBERON:0004765 ! composed primarily of skeletal element [Term] id: UBERON:0000076 name: external ectoderm namespace: uberon def: "The surface (external) layer of ectoderm which begins to proliferate shortly after separation from the neuroectoderm." [MGI:anna, MP:0012532] synonym: "surface (external) ectoderm" EXACT [] synonym: "surface ectoderm" EXACT [MP:0012532] xref: EHDAA2:0001968 xref: EHDAA:1494 xref: EHDAA:350 xref: EHDAA:4784 xref: EHDAA:4790 xref: EHDAA:4796 xref: EHDAA:7860 xref: EMAPA:16096 xref: FMA:87656 xref: NCIT:C34309 xref: UMLS:C1515087 {source="ncithesaurus:Surface_Ectoderm"} xref: Wikipedia:External_ectoderm is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium is_a: UBERON:0005291 ! embryonic tissue relationship: BFO:0000050 UBERON:0000924 {source="EHDAA2"} ! part of ectoderm property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/1/1d/Ectoderm.png" xsd:anyURI [Term] id: UBERON:0000077 name: mixed endoderm/mesoderm-derived structure namespace: uberon def: "An anatomical structure that develops from the endoderm and the mesoderm." [https://orcid.org/0000-0002-6601-2165] is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0000061 ! anatomical structure intersection_of: RO:0002202 UBERON:0000925 ! develops from endoderm intersection_of: RO:0002202 UBERON:0000926 ! develops from mesoderm property_value: IAO:0000232 "Grouping term for query purposes. Notes that the developmental relationships are being refined such that most structures should develop in whole from at most one layer, but may have contributions from multiple" xsd:string [Term] id: UBERON:0000078 name: mixed ectoderm/mesoderm/endoderm-derived structure namespace: uberon def: "An anatomical structure that develops from the ectoderm, mesoderm and endoderm." [https://orcid.org/0000-0002-6601-2165] is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0000061 ! anatomical structure intersection_of: RO:0002202 UBERON:0000924 ! develops from ectoderm intersection_of: RO:0002202 UBERON:0000925 ! develops from endoderm intersection_of: RO:0002202 UBERON:0000926 ! develops from mesoderm property_value: IAO:0000232 "Grouping term for query purposes. Notes that the developmental relationships are being refined such that most structures should develop in whole from at most one layer, but may have contributions from multiple" xsd:string [Term] id: UBERON:0000079 name: male reproductive system namespace: uberon def: "The organs associated with producing offspring in the gender that produces spermatozoa." [MP:0001145] synonym: "genitalia of male organism" EXACT [OBOL:automatic] synonym: "male genital system" EXACT [FMA:45664] synonym: "male genitalia" EXACT [] synonym: "male genitals" EXACT [] synonym: "male organism genitalia" EXACT [OBOL:automatic] synonym: "male organism reproductive system" EXACT [OBOL:automatic] synonym: "reproductive system of male organism" EXACT [OBOL:automatic] xref: BTO:0000082 xref: CALOHA:TS-1310 xref: EFO:0000970 xref: EHDAA2:0001054 xref: EHDAA:8136 xref: EMAPA:17968 xref: EV:0100101 xref: FMA:45664 xref: GAID:386 xref: HAO:0000505 xref: MA:0000396 xref: MESH:D005837 xref: NCIT:C12722 xref: SCTID:361340001 xref: TGMA:0000634 xref: UMLS:C0017422 {source="ncithesaurus:Male_Genitalia"} xref: UMLS:C1963704 {source="ncithesaurus:Male_Reproductive_System"} xref: VHOG:0000725 xref: Wikipedia:Male_reproductive_system_(human) xref: XAO:0000155 is_a: UBERON:0000990 ! reproductive system intersection_of: UBERON:0000990 ! reproductive system intersection_of: BFO:0000050 UBERON:0003101 ! part of male organism disjoint_from: UBERON:0000474 ! female reproductive system relationship: BFO:0000050 UBERON:0003101 ! part of male organism property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Prostate.glb" xsd:anyURI [Term] id: UBERON:0000080 name: mesonephros namespace: uberon def: "The second stage of the kidney. It serves as the main excretory organ of aquatic vertebrates and as a temporary embryonic kidney in higher vertebrates. It is composed of the mesonephric duct (also called the Wolffian duct), mesonephric tubules, and associated capillary tufts. A single tubule and its associated capillary tuft is called a mesonephric excretory unit; these units are similar in structure and function to nephrons of the adult kidney. The mesonephros is derived from intermediate mesoderm in the vertebrate embryo." [GO:0001823, Wikipedia:Mesonephros] synonym: "mesonephric kidney" EXACT [XAO:0000141] synonym: "Wolffian body" EXACT [BTO:0001542, GOC:yaf, MESH:A16.254.500, Wikipedia:Mesonephros] xref: AAO:0010384 xref: BTO:0001542 xref: CALOHA:TS-0624 xref: EFO:0000928 xref: EHDAA2:0001130 xref: EHDAA:1581 xref: EHDAA:5903 xref: EMAPA:16744 xref: FMA:72171 xref: GAID:1308 xref: MESH:D001755 xref: NCIT:C26467 xref: SCTID:308799002 xref: TAO:0000529 xref: UMLS:C0025492 {source="ncithesaurus:Mesonephros"} xref: VHOG:0000038 xref: Wikipedia:Mesonephros xref: XAO:0000141 xref: ZFA:0000529 is_a: UBERON:0002113 ! kidney is_a: UBERON:0004120 ! mesoderm-derived structure relationship: RO:0002202 UBERON:0002120 ! develops from pronephros property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/a/ad/Gray986.png" xsd:anyURI [Term] id: UBERON:0000081 name: metanephros namespace: uberon def: "In mammals, the metanephros is the excretory organ of the fetus, which develops into the mature kidney and is formed from the rear portion of the nephrogenic cord. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine[GO]." [GO:0001656, Wikipedia:Metanephros#Metanephros] synonym: "metanephron" EXACT [BTO:0001543] xref: BTO:0001543 xref: EHDAA2:0001137 xref: EHDAA:3089 xref: EHDAA:5911 xref: EMAPA:17373 xref: EMAPA_RETIRED:17207 xref: FMA:72172 xref: NCIT:C34209 xref: SCTID:308797000 xref: UMLS:C0231049 {source="ncithesaurus:Metanephros"} xref: VHOG:0000039 xref: Wikipedia:Metanephros#Metanephros is_a: UBERON:0002113 ! kidney is_a: UBERON:0004120 ! mesoderm-derived structure relationship: RO:0002202 UBERON:0003220 ! develops from metanephric mesenchyme relationship: RO:0002202 UBERON:0005080 {source="GO"} ! develops from metanephric ureteric bud relationship: RO:0002202 UBERON:0005753 ! develops from caudal part of nephrogenic cord relationship: RO:0002285 UBERON:0000080 {source="ISBN:9780878932504"} ! developmentally replaces mesonephros relationship: RO:0002492 UBERON:0000066 ! existence ends during fully formed stage [Term] id: UBERON:0000083 name: mesonephric tubule namespace: uberon def: "A mesonephric tubule is an epithelial tube that is part of the mesonephros[GO]. Genital ridge that is next to the mesonephros[WP]." [Wikipedia:Mesonephric_tubules] xref: AAO:0010389 xref: EHDAA2:0001134 xref: EMAPA:16747 xref: VHOG:0000500 xref: Wikipedia:Mesonephric_tubules xref: XAO:0000148 is_a: UBERON:0003914 ! epithelial tube is_a: UBERON:0005103 ! mesonephric epithelium is_a: UBERON:0006555 ! excretory tube intersection_of: UBERON:0003914 ! epithelial tube intersection_of: BFO:0000050 UBERON:0000080 ! part of mesonephros [Term] id: UBERON:0000084 name: ureteric bud namespace: uberon def: "An epithelial swelling on the Wolffian duct that elongates to invade the adjacent metanephric mesenchyme[MP]." [MP:0010979, PMID:19828308] xref: BTO:0001646 xref: EHDAA2:0002140 xref: EHDAA:3091 xref: EHDAA:5917 xref: EMAPA:17209 xref: NCIT:C34207 xref: SCTID:361528000 xref: UMLS:C1284058 {source="ncithesaurus:Metanephric_Diverticulum"} xref: VHOG:0000541 xref: Wikipedia:Ureteric_bud is_a: UBERON:0000083 ! mesonephric tubule is_a: UBERON:0007499 {source="EHDAA2"} ! epithelial sac is_a: UBERON:0034969 ! epithelial layer of duct relationship: BFO:0000050 UBERON:0003074 ! part of mesonephric duct relationship: RO:0002202 UBERON:0003074 {source="EHDAA2"} ! develops from mesonephric duct relationship: RO:0002256 UBERON:0003220 {source="ISBN:9780878932504"} ! developmentally induced by metanephric mesenchyme [Term] id: UBERON:0000085 name: morula namespace: uberon def: "A spherical embryonic mass of blastomeres formed before the blastula and resulting from cleavage of the fertilized ovum." [MP:0012130] xref: BTO:0001508 xref: EHDAA2:0000005 xref: FMA:292334 xref: GAID:1295 xref: MESH:D009028 xref: NCIT:C34212 xref: SCTID:361474003 xref: UMLS:C0026573 {source="ncithesaurus:Morula"} xref: Wikipedia:Morula is_a: UBERON:0000922 ! embryo relationship: BFO:0000050 UBERON:0004716 {source="EHDAA2"} ! part of conceptus relationship: BFO:0000051 CL:0000353 ! has part blastoderm cell relationship: RO:0002219 UBERON:0000086 ! surrounded by zona pellucida relationship: RO:0002488 UBERON:0000107 ! existence starts during cleavage stage relationship: RO:0002492 UBERON:0000107 ! existence ends during cleavage stage property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/c/c6/Blastulation.png" xsd:anyURI [Term] id: UBERON:0000086 name: zona pellucida namespace: uberon def: "A glycoprotein membrane surrounding the plasma membrane of an oocyte. It is a vital constitutive part of the latter, external but not extraneous to it. The zona pellucida first appears in multilaminar primary oocytes." [Wikipedia:Zona_pellucida] xref: BTO:0003135 xref: EHDAA2:0002220 xref: EHDAA:31 xref: EHDAA:62 xref: EMAPA:16035 xref: FMA:18674 xref: GAID:410 xref: MA:0001715 xref: MESH:D015044 xref: NCIT:C33896 xref: TAO:0001111 xref: UMLS:C0043519 {source="ncithesaurus:Zona_Pellucida"} xref: VHOG:0000720 xref: Wikipedia:Zona_pellucida xref: ZFA:0001111 is_a: UBERON:0005764 ! acellular membrane relationship: BFO:0000050 UBERON:0000992 ! part of ovary relationship: BFO:0000051 CHEBI:17089 ! has part glycoprotein relationship: RO:0002007 CL:0000023 ! bounding layer of oocyte property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/8/81/Gray3.png" xsd:anyURI [Term] id: UBERON:0000087 name: inner cell mass namespace: uberon def: "A mass of cells that develop into the body of the embryo and some extraembryonic tissues." [ISBN:0-683-40008-8, MGI:pvb] xref: EFO:0000547 xref: EHDAA2:0000830 xref: EHDAA:40 xref: EMAPA:16041 xref: FMA:86557 xref: NCIT:C13740 xref: SCTID:361456007 xref: UMLS:C1283994 {source="ncithesaurus:Inner_Cell_Mass"} xref: VHOG:0000742 xref: Wikipedia:Inner_cell_mass is_a: UBERON:0002050 ! embryonic structure relationship: RO:0002202 UBERON:0000358 {source="Wikipedia"} ! develops from blastocyst relationship: RO:0002219 UBERON:0000088 {source="Wikipedia"} ! surrounded by trophoblast property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/7/72/Blastocyst_English.svg" xsd:anyURI [Term] id: UBERON:0000088 name: trophoblast namespace: uberon def: "The mesectodermal cell layer arising from the trophectoderm that erodes the uterine mucosa and contributes to the formation of the placenta." [ISBN:0-683-40008-8, MP:0005031] synonym: "trophoblast layer" EXACT [MP:0005031] xref: BTO:0001079 xref: CALOHA:TS-1070 xref: EV:0100120 xref: FMA:83029 xref: GAID:1152 xref: MESH:D014327 xref: NCIT:C93292 xref: SCTID:362839005 xref: UMLS:C0041178 {source="ncithesaurus:Trophoblast"} xref: Wikipedia:Trophoblast is_a: UBERON:0002050 ! embryonic structure relationship: BFO:0000050 UBERON:0000358 ! part of blastocyst relationship: RO:0002202 UBERON:0004345 {source="MP-def", source="PMID:19829370"} ! develops from trophectoderm relationship: RO:0002473 CL:0000351 ! composed primarily of trophoblast cell property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/7/72/Blastocyst_English.svg" xsd:anyURI [Term] id: UBERON:0000091 name: bilaminar disc namespace: uberon def: "A flattened, almost circular bilaminar plate of cells formed when the inner cell mass (aka embryoblast) forms two epithelial layers, each of a distinct lineage, separated by an extracellular basement membrane: the external (dorsal) layer is called the epiblast and the internal (ventral) layer is called the hypoblast (aka primitive endoderm); together, they compose the bilaminar embryonic disc." [MP:0003886] synonym: "bilaminary embryonic disc" EXACT [] synonym: "bilaminary germ disc" EXACT [ISBN:9780878932504] xref: FMA:293863 xref: NCIT:C34112 xref: UMLS:C1283997 {source="ncithesaurus:Bilaminar_Embryonic_Disc"} xref: Wikipedia:Bilaminar_disc is_a: UBERON:0002050 ! embryonic structure relationship: RO:0002202 UBERON:0000087 {source="Wikipedia"} ! develops from inner cell mass property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/e/e3/Gray21.png" xsd:anyURI [Term] id: UBERON:0000092 name: post-embryonic stage namespace: uberon def: "Stage succeeding embryo, including mature structure." [https://orcid.org/0000-0002-6601-2165] synonym: "postembryonic stage" EXACT [] xref: BilaDO:0000003 xref: OGES:000010 xref: OGES:000014 xref: OGES:000024 xref: WBls:0000022 xref: WBls:0000093 xref: WBls:0000103 is_a: UBERON:0000105 ! life cycle stage relationship: BFO:0000062 UBERON:0000068 ! preceded by embryo stage relationship: RO:0002082 GO:0009791 ! simultaneous with post-embryonic development [Term] id: UBERON:0000094 name: membrane organ namespace: uberon def: "Nonparenchymatous organ that primarily consists of dense connective tissue organized into a sheet which interconnects two or more organs, separates two or more body spaces from one another, or surrounds an organ or body part. Examples: interosseous membrane of forearm, obturator membrane, tympanic membrane, fibrous pericardium, fascia lata, dura mater. [FMA]." [FMA:7145] synonym: "membrane of organ" EXACT [] xref: FMA:7145 is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000062 ! organ relationship: RO:0002473 UBERON:0011823 {source="FMA-def"} ! composed primarily of dense connective tissue creation_date: 2009-07-30T05:19:13Z [Term] id: UBERON:0000095 name: cardiac neural crest namespace: uberon def: "Portion of neural crest that develops from the dorsal neural tube. It overlaps the vagal neural crest and migrates to populate the pharyngeal arches 3, 4 and 6 (producing structures in the head) and to the heart, forming connective tissue that separates the great vessels of the heart. [Wikipedia]." [Wikipedia:Cardiac_neural_crest] xref: TAO:0002173 xref: Wikipedia:Cardiac_neural_crest xref: XAO:0004190 xref: ZFA:0001648 is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0005291 ! embryonic tissue relationship: BFO:0000050 UBERON:0002342 ! part of neural crest relationship: RO:0002131 UBERON:0005428 {source="Wikipedia"} ! overlaps vagal neural crest creation_date: 2009-07-30T07:57:38Z [Term] id: UBERON:0000101 name: lobe of lung namespace: uberon def: "A lung lobe is one of the rounded projections that compose the lung[GO]." [GOC:GO] synonym: "lung lobe" EXACT [] synonym: "pulminory lobe" EXACT [] synonym: "pulmonary lobe" EXACT [FMA:7311] xref: EMAPA:36281 xref: FMA:7311 xref: galen:LobeOfLung xref: MA:0003098 xref: NCIT:C34021 xref: SCTID:245524004 xref: UMLS:C0225752 {source="ncithesaurus:Lung_Lobe"} is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0009912 {source="FMA"} ! anatomical lobe relationship: BFO:0000050 UBERON:0002048 ! part of lung relationship: RO:0002433 UBERON:0002048 ! contributes to morphology of lung [Term] id: UBERON:0000102 name: lung vasculature namespace: uberon def: "The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs[GO]." [GOC:GO] synonym: "lung vascular network" EXACT [OBOL:automatic] synonym: "pulmonary vasculature" EXACT [FMA:73750] synonym: "vascular network of lung" EXACT [OBOL:automatic] synonym: "vasculature of lung" EXACT [OBOL:automatic] xref: FMA:73750 is_a: UBERON:0002201 ! vasculature of trunk is_a: UBERON:0006876 ! vasculature of organ intersection_of: UBERON:0002049 ! vasculature intersection_of: BFO:0000050 UBERON:0002048 ! part of lung relationship: BFO:0000050 UBERON:0002048 ! part of lung [Term] id: UBERON:0000104 name: life cycle namespace: uberon def: "An entire span of an organism's life. In metazoans, commences with the zygote stage and ends with the death of the organism." [https://orcid.org/0000-0002-6601-2165] synonym: "entire life cycle" EXACT [] synonym: "entire lifespan" EXACT [] synonym: "life" EXACT [] synonym: "lifespan" EXACT [] xref: FBdv:00000000 xref: HsapDv:0000001 xref: MmusDv:0000001 xref: ncithesaurus:Life xref: OGES:000011 is_a: UBERON:0000000 ! processual entity relationship: RO:0002224 UBERON:0000106 {gci_filler="NCBITaxon:33208", gci_relation="RO:0002162"} ! starts with zygote stage relationship: RO:0002230 UBERON:0000071 ! ends with death stage [Term] id: UBERON:0000105 name: life cycle stage namespace: uberon def: "A spatiotemporal region encompassing some part of the life cycle of an organism." [https://orcid.org/0000-0002-6601-2165] xref: BILS:0000105 xref: EFO:0000399 xref: FBdv:00007012 xref: FMA:24120 xref: HsapDv:0000000 xref: MESH:D008018 xref: MmusDv:0000000 xref: ncithesaurus:Developmental_Stage xref: OlatDv:0000010 xref: PdumDv:0000090 xref: WBls:0000002 xref: XAO:1000000 xref: ZFS:0000000 xref: ZFS:0100000 is_a: UBERON:0000000 ! processual entity relationship: BFO:0000050 UBERON:0000104 ! part of life cycle [Term] id: UBERON:0000106 name: zygote stage namespace: uberon def: "A stage at which the organism is a single cell produced by means of sexual reproduction." [Wikipedia:Zygote] synonym: "1-cell stage" EXACT [] synonym: "fertilized egg stage" EXACT [BTO:0000854] synonym: "one cell stage" EXACT [] xref: BilaDO:0000005 xref: BILS:0000106 xref: EFO:0001322 xref: EHDAA:27 xref: FBdv:00005288 xref: NCIT:C12601 xref: PdumDv:0000100 xref: VHOG:0000745 xref: Wikipedia:Zygote xref: XAO:1000001 xref: ZFS:0000001 is_a: UBERON:0000105 ! life cycle stage relationship: BFO:0000050 UBERON:0000068 ! part of embryo stage relationship: RO:0002223 UBERON:0000104 ! starts life cycle [Term] id: UBERON:0000107 name: cleavage stage namespace: uberon def: "The first few specialized divisions of an activated animal egg; Stage consisting of division of cells in the early embryo. The zygotes of many species undergo rapid cell cycles with no significant growth, producing a cluster of cells the same size as the original zygote. The different cells derived from cleavage are called blastomeres and form a compact mass called the morula. Cleavage ends with the formation of the blastula." [GO:0040016, Wikipedia:Cleavage_(embryo)] xref: BilaDO:0000006 xref: BILS:0000107 xref: EFO:0001290 xref: FBdv:00000054 xref: MESH:D002970 xref: MmusDv:0000004 xref: OGES:000015 xref: OGES:000020 xref: PdumDv:0000200 xref: Wikipedia:Cleavage_(embryo) xref: XAO:1000004 xref: ZFS:0000046 is_a: UBERON:0000105 ! life cycle stage intersection_of: UBERON:0000105 ! life cycle stage intersection_of: RO:0002082 GO:0040016 ! simultaneous with embryonic cleavage relationship: BFO:0000050 UBERON:0000068 ! part of embryo stage relationship: RO:0002082 GO:0040016 ! simultaneous with embryonic cleavage relationship: RO:0002087 UBERON:0000106 ! immediately preceded by zygote stage [Term] id: UBERON:0000108 name: blastula stage namespace: uberon def: "An early stage of embryonic development in animals. It is produced by cleavage of a fertilized ovum and consists of a spherical layer of around 128 cells surrounding a central fluid-filled cavity called the blastocoel. The blastula follows the morula and precedes the gastrula in the developmental sequence." [Wikipedia:Blastula] xref: BilaDO:0000007 xref: BILS:0000108 xref: EFO:0001282 xref: HsapDv:0000006 xref: MmusDv:0000007 xref: OGES:000003 xref: OGES:000016 xref: OGES:000021 xref: WBls:0000005 xref: Wikipedia:Blastula xref: XAO:1000003 xref: ZFS:0000045 is_a: UBERON:0000105 ! life cycle stage relationship: BFO:0000050 UBERON:0000068 ! part of embryo stage relationship: BFO:0000062 UBERON:0000107 ! preceded by cleavage stage property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/c/c6/Blastulation.png" xsd:anyURI [Term] id: UBERON:0000109 name: gastrula stage namespace: uberon def: "A stage defined by complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm." [GO:0007369] xref: BilaDO:0000008 xref: BILS:0000109 xref: EFO:0001296 xref: FBdv:00005317 xref: HsapDv:0000010 xref: MmusDv:0000013 xref: OGES:000004 xref: OGES:000019 xref: WBls:0000010 xref: XAO:1000005 xref: ZFS:0000047 is_a: UBERON:0000105 ! life cycle stage relationship: BFO:0000050 UBERON:0000068 ! part of embryo stage relationship: BFO:0000062 UBERON:0000108 {source="BILS"} ! preceded by blastula stage relationship: RO:0002082 GO:0007369 ! simultaneous with gastrulation relationship: RO:0002160 NCBITaxon:6072 ! only in taxon Eumetazoa [Term] id: UBERON:0000110 name: neurula stage namespace: uberon def: "Staged defined by the formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system." [GO:0001841] xref: BilaDO:0000009 xref: BILS:0000110 xref: HsapDv:0000012 xref: MmusDv:0000017 xref: XAO:1000006 is_a: UBERON:0000105 ! life cycle stage relationship: BFO:0000050 UBERON:0000068 ! part of embryo stage relationship: BFO:0000062 UBERON:0000109 ! preceded by gastrula stage relationship: RO:0002082 GO:0001841 ! simultaneous with neural tube formation relationship: RO:0002160 NCBITaxon:6072 ! only in taxon Eumetazoa [Term] id: UBERON:0000111 name: organogenesis stage namespace: uberon def: "A stage at which the ectoderm, endoderm, and mesoderm develop into the internal organs of the organism." [Wikipedia:Organogenesis] xref: BilaDO:0000010 xref: BILS:0000111 xref: HsapDv:0000015 xref: MmusDv:0000018 xref: OGES:000005 xref: OGES:000032 xref: Wikipedia:Organogenesis is_a: UBERON:0000105 ! life cycle stage relationship: BFO:0000050 UBERON:0000068 ! part of embryo stage relationship: BFO:0000062 UBERON:0000110 {gci_filler="NCBITaxon:32523", gci_relation="BFO:0000050"} ! preceded by neurula stage relationship: RO:0002082 GO:0048513 ! simultaneous with animal organ development relationship: RO:0002160 NCBITaxon:6072 ! only in taxon Eumetazoa [Term] id: UBERON:0000112 name: sexually immature stage namespace: uberon synonym: "immature stage" EXACT [VHOG:FB] xref: BILS:0000112 xref: BTO:0002168 xref: EFO:0001300 xref: EV:0300051 xref: MmusDv:0000043 xref: OGES:000009 xref: XAO:1000010 xref: XtroDO:0000083 xref: ZFS:0000051 is_a: UBERON:0000105 ! life cycle stage relationship: BFO:0000050 UBERON:0000066 ! part of fully formed stage relationship: BFO:0000062 UBERON:0000069 {gci_relation="BFO:0000050", gci_filler="NCBITaxon:7955", source="ZFS"} ! preceded by larval stage [Term] id: UBERON:0000113 name: post-juvenile adult stage namespace: uberon def: "The stage of being a sexually mature adult animal." [https://orcid.org/0000-0002-6601-2165] xref: BILS:0000113 xref: EV:0300064 xref: EV:0300070 xref: MIAA:0000403 xref: MmusDv:0000110 xref: OGES:000026 xref: OGES:000027 xref: XAO:1000093 xref: ZFS:0000044 is_a: UBERON:0000105 ! life cycle stage relationship: BFO:0000050 UBERON:0000066 ! part of fully formed stage relationship: BFO:0000062 UBERON:0000112 ! preceded by sexually immature stage [Term] id: UBERON:0000114 name: lung connective tissue namespace: uberon def: "The connective tissue located between the respiratory (airway and alveolar) epithelium, the capillary endothelium and pleural mesothelium; it contains basement membrane composed of collagen, elastin, proteoglycans, and fibronectin." [ISBN:0-683-40008-8, MGI:anna, MP:0002276, PMID:14635660] synonym: "connective tissue of lung" EXACT [OBOL:automatic] synonym: "pulmonary interstitium" EXACT [FMA:27533] xref: EMAPA:35521 xref: FMA:27533 xref: MA:0001782 xref: SCTID:201609008 is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure is_a: UBERON:0003580 ! lower respiratory tract connective tissue is_a: UBERON:0003837 ! thoracic segment connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: BFO:0000050 UBERON:0002048 ! part of lung relationship: BFO:0000050 UBERON:0002048 ! part of lung relationship: RO:0002433 UBERON:0002048 ! contributes to morphology of lung relationship: RO:0002494 UBERON:0004883 ! transformation of lung mesenchyme [Term] id: UBERON:0000115 name: lung epithelium namespace: uberon def: "The epithelial layer of the lung." [MP:0006382] synonym: "epithelial tissue of lung" EXACT [OBOL:automatic] synonym: "epithelium of lung" EXACT [OBOL:automatic] synonym: "lung epithelial tissue" EXACT [OBOL:automatic] xref: BTO:0001653 xref: EMAPA:32860 xref: MA:0001783 is_a: UBERON:0004815 ! lower respiratory tract epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: BFO:0000050 UBERON:0002048 ! part of lung relationship: BFO:0000050 UBERON:0002048 ! part of lung relationship: RO:0002202 UBERON:0001041 ! develops from foregut relationship: RO:0002433 UBERON:0002048 ! contributes to morphology of lung [Term] id: UBERON:0000117 name: respiratory tube namespace: uberon def: "A tube in the respiratory system. Examples: bronchus, bronchiole, trachea." [GO:0030323, http://orcid.org/0000-0002-6601-2165] synonym: "segment of tracheobronchial tree" EXACT [FMA:12224] xref: EMAPA:37946 {source="MA:th"} xref: FMA:12224 is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000025 ! tube is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: UBERON:0000025 ! tube intersection_of: BFO:0000050 UBERON:0000065 ! part of respiratory tract relationship: BFO:0000050 UBERON:0000065 ! part of respiratory tract relationship: BFO:0000051 UBERON:0000483 ! has part epithelium [Term] id: UBERON:0000118 name: lung bud namespace: uberon def: "Structure derived from foregut that becomes a lung[GO]." [GO:0060431, Wikipedia:Respiratory_bud] xref: BTO:0001643 xref: EHDAA2:0004089 xref: NCIT:C34260 xref: NCIT:C34282 xref: SCTID:361427007 xref: UMLS:C1514420 {source="ncithesaurus:Primary_Bronchial_Bud"} xref: UMLS:C1514897 {source="ncithesaurus:Respiratory_Diverticulum"} xref: Wikipedia:Respiratory_bud is_a: UBERON:0005153 {source="GO:0060441"} ! epithelial bud is_a: UBERON:0005911 ! endo-epithelium relationship: RO:0002202 UBERON:0005597 ! develops from lung primordium relationship: RO:0002202 UBERON:0008947 {source="EHDAA2"} ! develops from respiratory primordium relationship: RO:0002220 UBERON:0004872 ! adjacent to splanchnic layer of lateral plate mesoderm property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/7/71/Gray948.png" xsd:anyURI [Term] id: UBERON:0000122 name: neuron projection bundle namespace: uberon def: "A fasciculated bundle of neuron projections (GO:0043005), largely or completely lacking synapses." [CARO:0001001, FBbt:00005099, FBC:DOS] synonym: "funiculus" EXACT [] synonym: "nerve fiber bundle" EXACT [FBbt:00005099] synonym: "neural fiber bundle" EXACT [] xref: CARO:0001001 xref: NLX:147821 is_a: UBERON:0005162 ! multi cell part structure relationship: BFO:0000050 UBERON:0001016 ! part of nervous system relationship: BFO:0000051 GO:0043005 ! has part neuron projection [Term] id: UBERON:0000125 name: neural nucleus namespace: uberon def: "A spatially aggregated collection of nerve cell bodies in the CNS, consisting of one or more subpopulations that share cell type, chemical phenotype, and connections, and including nearby cells that share the same cell type, chemical phenotype, and connections. (CUMBO)." [NLX:28443] synonym: "nervous system nucleus" EXACT [] synonym: "neuraxis nucleus" EXACT [FMA:83686] synonym: "neuronal nucleus" EXACT [AEO:0000136] synonym: "nucleus of CNS" EXACT [NLX:28443] xref: AEO:0000136 xref: FMA:83686 xref: NCIT:C13197 xref: NLX:28443 xref: Wikipedia:Nucleus_(neuroanatomy) is_a: UBERON:0011215 ! central nervous system cell part cluster relationship: RO:0002160 NCBITaxon:7711 ! only in taxon Chordata relationship: RO:0002473 UBERON:0002020 ! composed primarily of gray matter [Term] id: UBERON:0000126 name: cranial nerve nucleus namespace: uberon def: "Nucleus that receives projections from or contains neurons that send projections through one of the cranial nerves." [NLX:28532] synonym: "cranial neural nucleus" EXACT [FMA:54501] synonym: "nucleus of cranial nerve" EXACT [] xref: EMAPA:37066 {source="MA:th"} xref: FMA:54501 xref: NLX:28532 xref: SCTID:280160003 xref: Wikipedia:Cranial_nerve_nucleus is_a: UBERON:0002308 ! nucleus of brain intersection_of: UBERON:0002308 ! nucleus of brain intersection_of: extends_fibers_into UBERON:0001785 ! cranial nerve relationship: BFO:0000050 RO:0002577 ! part of system relationship: extends_fibers_into UBERON:0001785 ! cranial nerve property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/3/30/Gray696.png" xsd:anyURI [Term] id: UBERON:0000153 name: anterior region of body namespace: uberon is_a: UBERON:0000475 ! organism subdivision disjoint_from: UBERON:0000154 {source="lexical"} ! posterior region of body relationship: BSPO:0000096 UBERON:0000154 ! anterior to posterior region of body relationship: RO:0002160 NCBITaxon:33213 ! only in taxon Bilateria [Term] id: UBERON:0000154 name: posterior region of body namespace: uberon is_a: UBERON:0000475 ! organism subdivision relationship: RO:0002160 NCBITaxon:33213 ! only in taxon Bilateria [Term] id: UBERON:0000158 name: membranous layer namespace: uberon synonym: "membranous organ component" EXACT [FMA:82500] xref: FMA:30322 xref: FMA:82500 xref: MESH:D008566 xref: NCIT:C12749 is_a: UBERON:0004923 ! organ component layer relationship: RO:0002007 UBERON:0000064 ! bounding layer of organ part [Term] id: UBERON:0000159 name: anal canal namespace: uberon def: "The terminal part of the large intestine, continuous proximally with the rectum and distally terminates with the anus." [Wikipedia:Anal_canal] synonym: "anal canal" EXACT [] synonym: "anal canal viewed anatomically" EXACT [] synonym: "anatomical anal canal" EXACT [] xref: BTO:0001978 xref: CALOHA:TS-2160 xref: EMAPA:18256 xref: FMA:15703 xref: galen:AnalCanal xref: MA:0000330 xref: NCIT:C12375 xref: SCTID:245438008 xref: UMLS:C0227411 {source="ncithesaurus:Anal_Canal"} xref: Wikipedia:Anal_canal is_a: UBERON:0004111 ! anatomical conduit is_a: UBERON:0004121 ! ectoderm-derived structure relationship: BFO:0000050 UBERON:0000059 ! part of large intestine relationship: BFO:0000050 UBERON:0001353 ! part of anal region relationship: channel_for UBERON:0001988 ! feces relationship: RO:0002150 UBERON:0001052 ! continuous with rectum relationship: RO:0002150 UBERON:0001245 ! continuous with anus relationship: RO:0002202 UBERON:0011272 {source="Wikipathways:WP2062"} ! develops from embryonic skin basal layer property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/0/01/Gray1078.png" xsd:anyURI [Term] id: UBERON:0000160 name: intestine namespace: uberon def: "Segment of the alimentary canal extending from the stomach to the anus and, in humans and other mammals, consists of two segments, the small intestine and the large intestine." [GOC:GO, Wikipedia:Intestine] synonym: "bowel" EXACT [] xref: AAO:0000246 xref: ANISEED:1235303 xref: BSA:0000093 xref: BTO:0000648 xref: CALOHA:TS-0490 xref: EFO:0000834 xref: EMAPA:32874 xref: EV:0100071 xref: FMA:7199 xref: GAID:295 xref: galen:Intestine xref: MA:0000328 xref: MA:0001524 xref: MESH:D007422 xref: MIAA:0000043 xref: NCIT:C12736 xref: SCTID:256876008 xref: TAO:0001338 xref: UMLS:C0021853 {source="ncithesaurus:Intestine"} xref: VHOG:0000056 xref: WBbt:0005772 xref: Wikipedia:Intestine xref: XAO:0000129 xref: ZFA:0001338 is_a: UBERON:0004921 {source="cjm"} ! subdivision of digestive tract relationship: BFO:0000050 UBERON:0005409 ! part of alimentary part of gastrointestinal system relationship: RO:0002433 UBERON:0001007 ! contributes to morphology of digestive system [Term] id: UBERON:0000161 name: orifice namespace: uberon def: "Anatomical conduit that connects two adjacent body spaces (or a body space with the space surrounding the organism)[FMA,modified]." [FMA:3724] synonym: "anatomical orifice" EXACT [FMA:3724] xref: FMA:3724 xref: SCTID:91837002 is_a: UBERON:0004111 ! anatomical conduit [Term] id: UBERON:0000162 name: cloaca namespace: uberon def: "Common chamber into which the intestines and excretory system opens. Arises during development in all vertebrates, but in many it becomes subdivided, lost or incorporated into other structures." [ISBN:0073040584, Wikipedia:Cloaca] xref: AAO:0000095 xref: GAID:1206 xref: MESH:D002988 xref: NCIT:C34127 xref: SCTID:362857006 xref: SCTID:370631000 xref: UMLS:C0008987 {source="ncithesaurus:Cloaca"} xref: VHOG:0001186 xref: Wikipedia:Cloaca xref: XAO:0000244 xref: ZFA:0005781 is_a: UBERON:0013522 ! subdivision of tube relationship: BFO:0000050 UBERON:0001555 {source="ZFA"} ! part of digestive tract relationship: BFO:0000050 UBERON:0004122 {source="AAO"} ! part of genitourinary system relationship: RO:0002160 NCBITaxon:7742 ! only in taxon Vertebrata [Term] id: UBERON:0000163 name: embryonic cloaca namespace: uberon def: "Endoderm-lined chamber that develops as pouch-like dilation of the caudal end of the hindgut and receives the allantois ventrally and two mesonephric ducts laterally; caudally it ends blindly at the cloacal membrane formed by the union of proctodeal (anal pit) ectoderm and cloacal endoderm, with no intervening mesoderm[MP]." [MP:0010115, Wikipedia:Cloaca_(embryology)] xref: EHDAA2:0000256 xref: EHDAA:4895 xref: EMAPA:27573 xref: Wikipedia:Cloaca_(embryology) is_a: UBERON:0000162 ! cloaca relationship: BFO:0000050 UBERON:0000922 ! part of embryo relationship: BFO:0000050 UBERON:0001008 {source="EHDAA2"} ! part of renal system relationship: BFO:0000050 UBERON:0012361 {source="EHDAA2"} ! part of internal anal region relationship: RO:0002254 UBERON:0003064 ! has developmental contribution from intermediate mesoderm property_value: IAO:0000232 "this class represents the embryonic form of the cloaca, as found in both mammals and non-mammals." xsd:string [Term] id: UBERON:0000164 name: primitive urogenital sinus namespace: uberon def: "The ventral part of the cloaca remaining after septation of the rectum, which further develops into part of the bladder, part of the prostatic part of the male urethra and the urethra and vestibule in females." [ISBN:0-683-40008-8, MP:0010116] synonym: "fetal UGS" EXACT [PMID:18977204] synonym: "UGS" EXACT [MP:0010116] xref: EHDAA2:0004060 xref: EHDAA:5029 xref: EHDAA:5919 xref: EMAPA:17379 xref: NCIT:C34322 xref: SCTID:50961009 xref: UMLS:C0231057 {source="ncithesaurus:Urogenital_Sinus"} xref: VHOG:0000414 xref: Wikipedia:Definitive_urogenital_sinus is_a: UBERON:0002050 ! embryonic structure relationship: BFO:0000050 UBERON:0000163 {source="MP-def"} ! part of embryonic cloaca relationship: RO:0002160 NCBITaxon:7742 ! only in taxon Vertebrata relationship: RO:0002202 UBERON:0003064 ! develops from intermediate mesoderm relationship: RO:0002433 UBERON:0000163 ! contributes to morphology of embryonic cloaca property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/6/6d/Gray1109.png" xsd:anyURI [Term] id: UBERON:0000165 name: mouth namespace: uberon def: "The proximal portion of the digestive tract, containing the oral cavity and bounded by the oral opening. In vertebrates, this extends to the pharynx and includes gums, lips, tongue and parts of the palate. Typically also includes the teeth, except where these occur elsewhere (e.g. pharyngeal jaws) or protrude from the mouth (tusks)." [https://github.com/obophenotype/uberon/wiki/The-digestive-tract, Wikipedia:Mouth] xref: AAO:0010355 xref: BTO:0001090 xref: BTO:0004698 xref: CALOHA:TS-1315 xref: EFO:0000825 xref: EHDAA2:0001326 xref: EHDAA:542 xref: EMAPA:16262 xref: FMA:49184 xref: GAID:75 xref: galen:Mouth xref: http://purl.obolibrary.org/obo/uberon/images/lamprey_sucker_rosava_3238889218.jpg xref: MA:0000341 xref: MA:0002474 xref: MAT:0000038 xref: MESH:D009055 xref: MIAA:0000038 xref: SCTID:21082005 xref: TADS:0000040 xref: TAO:0000547 xref: TAO:0000590 xref: TGMA:0000131 xref: VHOG:0000280 xref: VHOG:0000812 xref: Wikipedia:Mouth xref: XAO:0003029 xref: ZFA:0000547 xref: ZFA:0000590 is_a: UBERON:0004921 ! subdivision of digestive tract intersection_of: UBERON:0004921 ! subdivision of digestive tract intersection_of: BSPO:0001106 UBERON:0001555 ! proximalmost part of digestive tract relationship: BSPO:0001106 UBERON:0001555 ! proximalmost part of digestive tract relationship: RO:0002160 NCBITaxon:6072 ! only in taxon Eumetazoa relationship: RO:0002202 UBERON:0035804 ! develops from future mouth property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/0/06/Mouth_illustration-Otis_Archives.jpg" xsd:anyURI [Term] id: UBERON:0000166 name: oral opening namespace: uberon def: "The orifice that connects the mouth to the exterior of the body." [https://github.com/obophenotype/uberon/wiki/The-digestive-tract] synonym: "oral fissure" EXACT [FMA:59806] synonym: "oral orifice" EXACT [FMA:59806] xref: FMA:59806 is_a: UBERON:0000161 {source="FMA"} ! orifice relationship: BFO:0000050 UBERON:0000165 ! part of mouth relationship: RO:0002131 UBERON:0001004 {gci_filler="NCBITaxon:32523", gci_relation="BFO:0000050"} ! overlaps respiratory system [Term] id: UBERON:0000167 name: oral cavity namespace: uberon def: "Anatomical cavity at the start of the digestive tract that that is enclosed by the mouth. The boundaries and contents vary depending on the species. In vertebrates, the boundaries are the oral opening, the cheeks, the palate and (if present) the palatoglossal arch - if this is not present then the mouth and pharynx form the oropharyngeal cavity. The buccal cavity contains the teeth, tongue and palate (when present)." [https://github.com/obophenotype/uberon/wiki/The-digestive-tract, https://orcid.org/0000-0002-6601-2165, ISBN:0073040584] synonym: "buccal cavity" EXACT [FMA:20292, ISBN:0073040584] synonym: "cavity of mouth" EXACT [] xref: AAO:0000053 xref: AAO:0000960 xref: BSA:0000107 xref: CALOHA:TS-1315 xref: EFO:0001975 xref: EHDAA2:0001324 xref: EHDAA:6970 xref: EMAPA:17411 xref: EMAPA:18399 xref: EV:0100057 xref: FMA:20292 xref: HAO:0000669 xref: NCIT:C12421 xref: SCTID:181220002 xref: TAO:0001027 xref: TGMA:0000102 xref: UMLS:C0226896 {source="ncithesaurus:Oral_Cavity"} xref: VHOG:0000188 xref: WBbt:0005255 xref: XAO:0000126 xref: ZFA:0001027 is_a: UBERON:0002553 ! anatomical cavity intersection_of: UBERON:0000464 ! anatomical space intersection_of: RO:0002572 UBERON:0000165 ! luminal space of mouth relationship: RO:0002433 UBERON:0000165 ! contributes to morphology of mouth relationship: RO:0002572 UBERON:0000165 ! luminal space of mouth [Term] id: UBERON:0000168 name: proximal-distal subdivision of colon namespace: uberon def: "A section dividing a colon along a proximal-distal axis." [http://orcid.org/0000-0002-6601-2165] xref: FMA:222905 is_a: UBERON:0004921 ! subdivision of digestive tract intersection_of: UBERON:0013522 ! subdivision of tube intersection_of: subdivision_of UBERON:0001155 ! colon relationship: BFO:0000050 UBERON:0001155 ! part of colon relationship: subdivision_of UBERON:0001155 ! colon [Term] id: UBERON:0000170 name: pair of lungs namespace: uberon def: "The pair of anatomical structures comprised of a left lung and right lung." [http://orcid.org/0000-0002-6601-2165] synonym: "lungs" EXACT [] synonym: "lungs pair" EXACT [] synonym: "set of lungs" EXACT [] xref: FMA:68877 is_a: UBERON:0034925 ! anatomical collection intersection_of: UBERON:0034925 ! anatomical collection intersection_of: RO:0002351 UBERON:0002167 ! has member right lung intersection_of: RO:0002351 UBERON:0002168 ! has member left lung relationship: BFO:0000050 UBERON:0001558 {source="FMA-abduced"} ! part of lower respiratory tract relationship: RO:0001025 UBERON:0002224 ! located in thoracic cavity relationship: RO:0002351 UBERON:0002167 ! has member right lung relationship: RO:0002351 UBERON:0002167 {cardinality="1"} ! has member right lung relationship: RO:0002351 UBERON:0002168 ! has member left lung relationship: RO:0002351 UBERON:0002168 {cardinality="1"} ! has member left lung [Term] id: UBERON:0000171 name: respiration organ namespace: uberon def: "Organ that functions in gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms." [GO:0007585] synonym: "apparatus respiratorius organ" EXACT [OBOL:automatic] synonym: "breathing organ" EXACT [] synonym: "organ of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "organ of respiratory system" EXACT [OBOL:automatic] synonym: "respiratory organ" EXACT [] synonym: "respiratory system organ" EXACT [OBOL:automatic] xref: EMAPA:17607 xref: SCTID:272626006 xref: SPD:0000428 xref: TGMA:0001247 is_a: UBERON:0000062 ! organ intersection_of: UBERON:0000062 ! organ intersection_of: RO:0002215 GO:0007585 ! capable of respiratory gaseous exchange by respiratory system relationship: BFO:0000050 UBERON:0001004 ! part of respiratory system relationship: RO:0002215 GO:0007585 ! capable of respiratory gaseous exchange by respiratory system [Term] id: UBERON:0000174 name: excreta namespace: uberon def: "A portion of organism substance that is the product of an excretion process that will be eliminated from the body. An excretion process is elimination by an organism of the waste products that arise as a result of metabolic activity." [GO:0007588, http://orcid.org/0000-0002-6601-2165] synonym: "excreted substance" EXACT [] synonym: "portion of excreted substance" EXACT [FMA:9674] synonym: "waste substance" EXACT [AEO:0000184] xref: AEO:0000184 xref: BTO:0000491 xref: EHDAA2_RETIRED:0003184 xref: ENVO:02000022 xref: FMA:9674 xref: galen:Excretion is_a: UBERON:0000463 ! organism substance intersection_of: UBERON:0000463 ! organism substance intersection_of: RO:0002353 GO:0007588 ! output of excretion relationship: RO:0002353 GO:0007588 ! output of excretion [Term] id: UBERON:0000178 name: blood namespace: uberon def: "A fluid that is composed of blood plasma and erythrocytes." [FMA:9670, http://orcid.org/0000-0002-6601-2165, https://github.com/obophenotype/uberon/issues/9, Wikipedia:Blood] synonym: "portion of blood" EXACT [] synonym: "vertebrate blood" EXACT [] xref: AAO:0000046 xref: BTO:0000089 xref: CALOHA:TS-0079 xref: EFO:0000296 xref: EHDAA2:0000176 xref: EHDAA:418 xref: EMAPA:16332 xref: ENVO:02000027 xref: EV:0100047 xref: FMA:9670 xref: GAID:965 xref: galen:Blood xref: MA:0000059 xref: MESH:D001769 xref: MIAA:0000315 xref: NCIT:C12434 xref: TAO:0000007 xref: UMLS:C0005767 {source="ncithesaurus:Blood"} xref: VHOG:0000224 xref: Wikipedia:Blood xref: XAO:0000124 xref: ZFA:0000007 is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000179 ! haemolymphatic fluid relationship: BFO:0000050 UBERON:0002390 ! part of hematopoietic system relationship: BFO:0000051 CL:0000232 {source="CL:tm"} ! has part erythrocyte relationship: BFO:0000051 UBERON:0001969 ! has part blood plasma relationship: RO:0001025 UBERON:0002049 {source="https://github.com/obophenotype/uberon/issues/1330"} ! located in vasculature relationship: RO:0002495 UBERON:0006596 {source="Bgee:AN"} ! immediate transformation of presumptive blood property_value: IAO:0000232 "This class excludes blood analogues, such as the insect analog of blood. See UBERON:0000179 haemolymphatic fluid." xsd:string property_value: x_1.1:contributor https://github.com/cmungall property_value: x_1.1:contributor https://github.com/tmeehan [Term] id: UBERON:0000179 name: haemolymphatic fluid namespace: uberon def: "Circulating fluid that is part of the hemolymphoid system. Blood, lymph, interstitial fluid or its analogs." [http://orcid.org/0000-0002-6601-2165] xref: CARO:0000081 is_a: UBERON:0006314 ! bodily fluid intersection_of: UBERON:0000463 ! organism substance intersection_of: BFO:0000050 UBERON:0002193 ! part of hemolymphoid system relationship: BFO:0000050 UBERON:0002193 ! part of hemolymphoid system relationship: RO:0002160 NCBITaxon:6072 ! only in taxon Eumetazoa creation_date: 2009-04-08T04:38:19Z [Term] id: UBERON:0000209 name: tetrapod frontal bone namespace: uberon def: "The bone forming the forehead and roof of the eye orbit." [ISBN:0-683-40008-8, MP:0000107, PMID:7914451, Wikipedia:Frontal_bone] xref: AAO:0000206 xref: EMAPA:19016 xref: FMA:52734 xref: GAID:226 xref: MA:0001466 xref: MESH:D005624 xref: NCIT:C32635 xref: SCTID:181793006 xref: UMLS:C0016732 {source="ncithesaurus:Frontal_Bone"} xref: VHOG:0001324 xref: VSAO:0000208 xref: Wikipedia:Frontal_bone is_a: UBERON:0002514 ! intramembranous bone is_a: UBERON:0008907 ! dermal bone is_a: UBERON:0010428 {source="FMA"} ! flat bone is_a: UBERON:0011164 ! neurocranium bone relationship: BFO:0000050 UBERON:0003113 {source="cjm"} ! part of dermatocranium relationship: RO:0002131 UBERON:0001697 ! overlaps orbit of skull relationship: RO:0002170 UBERON:0001677 {gci_filler="NCBITaxon:9606", gci_relation="BFO:0000050", source="FMA"} ! connected to sphenoid bone relationship: RO:0002170 UBERON:0001679 {gci_filler="NCBITaxon:9606", gci_relation="BFO:0000050", source="FMA"} ! connected to ethmoid bone property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/9/97/Gray136.png" xsd:anyURI property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/5/5b/Frontal_bone.png" xsd:anyURI [Term] id: UBERON:0000211 name: ligament namespace: uberon def: "Dense regular connective tissue connecting two or more adjacent skeletal elements or supporting an organ." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, VSAO:0000073] synonym: "ligament organ" EXACT [FMA:21496] xref: CALOHA:TS-2145 xref: EFO:0001966 xref: EMAPA:35493 xref: FMA:21496 xref: FMA:30319 xref: galen:Ligament xref: MA:0000113 xref: MESH:D008022 xref: NCIT:C13046 xref: SCTID:182358004 xref: TAO:0001682 xref: UMLS:C0023685 {source="ncithesaurus:Ligament"} xref: VHOG:0001272 xref: Wikipedia:Ligament xref: XAO:0004031 xref: ZFA:0001675 is_a: UBERON:0000062 ! organ relationship: BFO:0000051 UBERON:0002384 ! has part connective tissue relationship: RO:0002160 NCBITaxon:33213 ! only in taxon Bilateria property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/9/9a/Knee_diagram.svg" xsd:anyURI [Term] id: UBERON:0000219 name: vertebral foramen of atlas namespace: uberon synonym: "vertebral foramen of cervical vertebra 1" EXACT [] xref: FMA:24293 xref: SCTID:281228008 xref: Wikipedia:Atlas_(anatomy)#Vertebral_foramen is_a: UBERON:0001131 ! vertebral foramen is_a: UBERON:0005744 ! bone foramen intersection_of: UBERON:0001131 ! vertebral foramen intersection_of: BFO:0000050 UBERON:0001092 ! part of vertebral bone 1 relationship: BFO:0000050 UBERON:0001092 ! part of vertebral bone 1 [Term] id: UBERON:0000220 name: atlanto-occipital joint namespace: uberon def: "The Atlanto-occipital joint (articulation between the atlas and the occipital bone) consists of a pair of condyloid joints. The atlanto-occipital joint is a synovial joint. The ligaments connecting the bones are: Two Articular capsules; Posterior atlantoöccipital membrane; Anterior atlantoöccipital membrane; Lateral atlantoöccipital." [Wikipedia:Atlanto-occipital_joint] synonym: "articulatio atlanto-occipitalis" EXACT [FMA:24939] synonym: "atlanto occipital joint" EXACT [] synonym: "atlantooccipital joint" EXACT [] synonym: "craniovertebral joint" EXACT [FMA:24939] synonym: "occipito atlantal joint" EXACT [] synonym: "occipito-atlantal joint" EXACT [] xref: FMA:24939 xref: NCIT:C32158 xref: ncithesaurus:Atlanto-occipital_Joint-Atlanto xref: SCTID:361831006 xref: UMLS:C0004169 {source="ncithesaurus:Atlanto-occipital_Joint"} xref: Wikipedia:Atlanto-occipital_joint is_a: UBERON:0002217 ! synovial joint is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0002217 ! synovial joint intersection_of: RO:0002176 UBERON:0001092 ! connects vertebral bone 1 intersection_of: RO:0002176 UBERON:0001676 ! connects occipital bone relationship: BSPO:0000126 UBERON:0006072 {source="FMA-abduced-lr"} ! in lateral side of cervical region of vertebral column relationship: RO:0002176 UBERON:0001092 ! connects vertebral bone 1 relationship: RO:0002176 UBERON:0001676 ! connects occipital bone property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/d/d4/Gray304.png" xsd:anyURI [Term] id: UBERON:0000304 name: tendon sheath namespace: uberon def: "A layer of membrane around a tendon. It has 2 layers: synovial sheath + fibrous tendon sheath." [Wikipedia:Tendon_sheath] synonym: "synovial tendon sheath" EXACT [FMA:45087] xref: BTO:0000051 xref: FMA:45087 xref: FMA:76715 xref: NCIT:C96299 xref: SCTID:361885006 xref: UMLS:C0224856 {source="ncithesaurus:Tendon_Sheath"} xref: Wikipedia:Tendon_sheath is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0004923 ! organ component layer intersection_of: UBERON:0004923 ! organ component layer intersection_of: RO:0002007 UBERON:0000043 ! bounding layer of tendon relationship: BFO:0000051 UBERON:0011233 ! has part synovial membrane of synovial tendon sheath relationship: BFO:0000051 UBERON:0011234 ! has part fibrous membrane of synovial tendon sheath relationship: RO:0002007 UBERON:0000043 ! bounding layer of tendon [Term] id: UBERON:0000307 name: blastula namespace: uberon def: "Organism at the blastula stage - an early stage of embryonic development in animals. It is produced by cleavage of a fertilized ovum and consists of a spherical layer of around 128 cells surrounding a central fluid-filled cavity called the blastocoel. The blastula follows the morula and precedes the gastrula in the developmental sequence." [Wikipedia:Blastula] synonym: "blastula embryo" EXACT [BILA:0000059] xref: BILA:0000059 xref: BTO:0000128 xref: GAID:1294 xref: MESH:D036703 xref: OGEM:000006 xref: Wikipedia:Blastula is_a: UBERON:0000922 ! embryo intersection_of: UBERON:0000468 ! multicellular organism intersection_of: RO:0002491 UBERON:0000108 ! existence starts and ends during blastula stage relationship: RO:0002202 UBERON:0007010 ! develops from cleaving embryo relationship: RO:0002491 UBERON:0000108 ! existence starts and ends during blastula stage property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/c/c6/Blastulation.png" xsd:anyURI [Term] id: UBERON:0000317 name: colonic mucosa namespace: uberon def: "Mucosa that is part of a colon. The mucosa of the colon is lined by a simple columnar epithelium with a thin brush border and numerous goblet cells." [http://orcid.org/0000-0002-6601-2165] synonym: "colon mucosa" EXACT [FMA:14984] synonym: "colon mucous membrane" EXACT [OBOL:automatic] synonym: "colonic mucosa" EXACT [] synonym: "colonic mucous membrane" EXACT [FMA:14984] synonym: "large bowel mucosa" EXACT [OBOL:automatic] synonym: "mucosa of colon" EXACT [FMA:14984] synonym: "mucosa of large bowel" EXACT [OBOL:automatic] xref: BTO:0000271 xref: CALOHA:TS-0164 xref: EFO:0003038 xref: EMAPA:27375 xref: FMA:14984 xref: FMA:85388 xref: MA:0003194 xref: SCTID:362157008 is_a: UBERON:0001207 ! mucosa of large intestine intersection_of: UBERON:0000344 ! mucosa intersection_of: BFO:0000050 UBERON:0001155 ! part of colon relationship: BFO:0000050 UBERON:0001155 ! part of colon [Term] id: UBERON:0000320 name: duodenal mucosa namespace: uberon def: "A mucosa that is part of a duodenum [Automatically generated definition]." [OBOL:automatic] synonym: "doudenal mucosa" EXACT [FMA:14942] synonym: "duodenal mucous membrane" EXACT [FMA:14942] synonym: "mucosa of duodenum" EXACT [OBOL:automatic] synonym: "mucous membrane of duodenum" EXACT [OBOL:automatic] xref: BTO:0000367 xref: CALOHA:TS-0213 xref: EMAPA:27235 xref: FMA:14942 xref: MA:0003207 xref: SCTID:362146003 is_a: UBERON:0001204 ! mucosa of small intestine intersection_of: UBERON:0000344 ! mucosa intersection_of: BFO:0000050 UBERON:0002114 ! part of duodenum relationship: BFO:0000050 UBERON:0002114 ! part of duodenum [Term] id: UBERON:0000323 name: late embryo namespace: uberon def: "An embryo that is at the late embryonic stage; this stage covers late steps of the embryogenesis with a fully formed embryo still developing before birth or egg hatching." [https://orcid.org/0000-0003-3308-6245] xref: BTO:0000449 xref: CALOHA:TS-0360 xref: EFO:0001323 xref: FMA:63919 xref: GAID:552 xref: MESH:D005333 xref: NCIT:C13235 xref: SCTID:83418008 xref: UMLS:C0015965 {source="ncithesaurus:Fetus"} is_a: UBERON:0000922 ! embryo intersection_of: UBERON:0000922 ! embryo intersection_of: RO:0002491 UBERON:0007220 ! existence starts and ends during late embryonic stage relationship: RO:0002491 UBERON:0007220 ! existence starts and ends during late embryonic stage [Term] id: UBERON:0000325 name: gastric gland namespace: uberon def: "The branched tubular glands found in the mucosa of the fundus and body of the stomach which contain parietal cells that secrete hydrochloric acid and zymogenic cells that produce pepsin." [MGI:anna] xref: BTO:0000503 xref: EMAPA:27181 xref: FMA:14919 is_a: UBERON:0002365 {source="cjm"} ! exocrine gland is_a: UBERON:0003294 ! gland of foregut relationship: BFO:0000050 UBERON:0006924 {source="ISBN:0073040584"} ! part of stomach glandular epithelium [Term] id: UBERON:0000326 name: pancreatic juice namespace: uberon def: "Pancreatic juice is slightly alkaline and contains numerous enzymes and inactive enzyme precursors including alpha-amylase, chymotrypsinogen, lipase, procarboxypeptidase, proelastase, prophospholipase A2, ribonuclease, and trypsinogen. Its high concentration of bicarbonate ions helps to neutralize the acid from the stomach." [GO:0030157] xref: BTO:0000504 xref: CALOHA:TS-2235 xref: FMA:62973 xref: GAID:1166 xref: MESH:D010189 is_a: UBERON:0000456 ! secretion of exocrine gland intersection_of: UBERON:0000456 ! secretion of exocrine gland intersection_of: RO:0003001 UBERON:0001264 ! produced by pancreas relationship: RO:0003001 UBERON:0001264 ! produced by pancreas [Term] id: UBERON:0000328 name: gut wall namespace: uberon def: "The wall of the digestive tract. This encompasses all parts of the digestive tract with the exception of the lumen (cavity)." [http://orcid.org/0000-0002-6601-2165] synonym: "digestive tract wall" EXACT [] synonym: "wall of digestive tract" EXACT [] synonym: "wall of gut" EXACT [FMA:45653] xref: BTO:0000547 xref: FMA:45653 is_a: UBERON:0000060 ! anatomical wall intersection_of: UBERON:0000060 ! anatomical wall intersection_of: BFO:0000050 UBERON:0001555 ! part of digestive tract relationship: BFO:0000050 UBERON:0001555 ! part of digestive tract property_value: IAO:0000232 "We model the digestive tract as consisting of two parts: the wall and the lumen." xsd:string [Term] id: UBERON:0000332 name: yellow bone marrow namespace: uberon def: "Bone marrow in which the fat cells predominate in the meshes of the reticular network." [http://medical-dictionary.thefreedictionary.com/Yellow+Marrow] synonym: "yellow marrow" EXACT [BTO:0000635] xref: BTO:0000635 xref: FMA:74596 xref: SCTID:328639002 xref: SCTID:5023006 is_a: UBERON:0002371 ! bone marrow intersection_of: UBERON:0002371 ! bone marrow intersection_of: RO:0002473 CL:0000136 ! composed primarily of adipocyte relationship: BFO:0000050 UBERON:0007195 ! part of stroma of bone marrow relationship: RO:0002473 CL:0000136 ! composed primarily of adipocyte [Term] id: UBERON:0000333 name: intestinal gland namespace: uberon def: "A gland that is part of the intestinal mucosa. Examples include the intestinal crypts, duodenal gland[cjm]." [https://orcid.org/0000-0002-6601-2165] synonym: "bowel mucosa gland" EXACT [OBOL:automatic] synonym: "bowel mucosa of organ gland" EXACT [OBOL:automatic] synonym: "bowel mucous membrane gland" EXACT [OBOL:automatic] synonym: "bowel organ mucosa gland" EXACT [OBOL:automatic] synonym: "gland of bowel mucosa" EXACT [OBOL:automatic] synonym: "gland of bowel mucosa of organ" EXACT [OBOL:automatic] synonym: "gland of bowel mucous membrane" EXACT [OBOL:automatic] synonym: "gland of bowel organ mucosa" EXACT [OBOL:automatic] synonym: "gland of intestinal mucosa" EXACT [OBOL:automatic] synonym: "gland of intestine mucosa" EXACT [OBOL:automatic] synonym: "gland of intestine mucosa of organ" EXACT [OBOL:automatic] synonym: "gland of intestine mucous membrane" EXACT [OBOL:automatic] synonym: "gland of intestine organ mucosa" EXACT [OBOL:automatic] synonym: "gland of mucosa of bowel" EXACT [OBOL:automatic] synonym: "gland of mucosa of intestine" EXACT [OBOL:automatic] synonym: "gland of mucosa of organ of bowel" EXACT [OBOL:automatic] synonym: "gland of mucosa of organ of intestine" EXACT [OBOL:automatic] synonym: "gland of mucous membrane of bowel" EXACT [OBOL:automatic] synonym: "gland of mucous membrane of intestine" EXACT [OBOL:automatic] synonym: "gland of organ mucosa of bowel" EXACT [OBOL:automatic] synonym: "gland of organ mucosa of intestine" EXACT [OBOL:automatic] synonym: "glandula intestinalis" EXACT [FMA:15052] synonym: "intestinal mucosa gland" EXACT [OBOL:automatic] synonym: "intestine mucosa gland" EXACT [OBOL:automatic] synonym: "intestine mucosa of organ gland" EXACT [OBOL:automatic] synonym: "intestine mucous membrane gland" EXACT [OBOL:automatic] synonym: "intestine organ mucosa gland" EXACT [OBOL:automatic] synonym: "mucosa of bowel gland" EXACT [OBOL:automatic] synonym: "mucosa of intestine gland" EXACT [OBOL:automatic] synonym: "mucosa of organ of bowel gland" EXACT [OBOL:automatic] synonym: "mucosa of organ of intestine gland" EXACT [OBOL:automatic] synonym: "mucous membrane of bowel gland" EXACT [OBOL:automatic] synonym: "mucous membrane of intestine gland" EXACT [OBOL:automatic] synonym: "organ mucosa of bowel gland" EXACT [OBOL:automatic] synonym: "organ mucosa of intestine gland" EXACT [OBOL:automatic] xref: BTO:0000640 xref: FMA:15052 xref: SCTID:266297002 is_a: UBERON:0003408 ! gland of digestive tract intersection_of: UBERON:0002530 ! gland intersection_of: BFO:0000050 UBERON:0001242 ! part of intestinal mucosa relationship: BFO:0000050 UBERON:0001242 ! part of intestinal mucosa [Term] id: UBERON:0000344 name: mucosa namespace: uberon def: "A lining of mostly endodermal origin, covered in epithelium, which is involved in absorption and secretion. They line various body cavities that are exposed to the external environment and internal organs. It is at several places continuous with skin: at the nostrils, the lips, the ears, the genital area, and the anus. The sticky, thick fluid secreted by the mucous membranes and gland is termed mucus. The term mucous membrane refers to where they are found in the body and not every mucous membrane secretes mucus[WP]." [Wikipedia:Mucous_membrane] synonym: "mucosa of organ" EXACT [FMA:85355] synonym: "mucosa of organ part" EXACT [FMA:85358] synonym: "mucosal region" EXACT [FMA:85358] synonym: "mucous membrane" EXACT [FMA:85355] synonym: "organ mucosa" EXACT [FMA:85355] xref: AEO:0000199 xref: BTO:0000886 xref: CALOHA:TS-2031 xref: EHDAA2_RETIRED:0003234 xref: EV:0100382 xref: FMA:85355 xref: FMA:85358 xref: GAID:297 xref: galen:Mucosa xref: MESH:D009092 xref: NCIT:C13166 xref: SCTID:361693009 xref: UMLS:C0026724 {source="ncithesaurus:Mucosa"} xref: Wikipedia:Mucous_membrane is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0004923 ! organ component layer relationship: BFO:0000051 UBERON:0000483 ! has part epithelium relationship: BFO:0000051 UBERON:0002384 ! has part connective tissue relationship: RO:0002160 NCBITaxon:7711 ! only in taxon Chordata property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/4/4e/Ens.png" xsd:anyURI property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/en/thumb/4/4e/Ens.png/200px-Ens.png" xsd:anyURI [Term] id: UBERON:0000353 name: parenchyma namespace: uberon def: "Functional part of an organ in the body. This is in contrast to the stroma, which refers to the structural tissue of organs, being exactly, connective tissues." [Wikipedia:Parenchyma] xref: EHDAA:3015 xref: EHDAA:3905 xref: EHDAA:3999 xref: EHDAA:4005 xref: EHDAA:6899 xref: EHDAA:6903 xref: EHDAA:6994 xref: EHDAA:8086 xref: EHDAA:9182 xref: EHDAA:9190 xref: EHDAA:9196 xref: EHDAA:9202 xref: FMA:45732 xref: NCIT:C74601 xref: UMLS:C0933845 {source="ncithesaurus:Parenchyma"} xref: Wikipedia:Parenchyma is_a: UBERON:0000064 ! organ part disjoint_from: UBERON:0003891 ! stroma relationship: RO:0002160 NCBITaxon:6072 ! only in taxon Eumetazoa relationship: RO:0002215 GO:0032501 ! capable of multicellular organismal process [Term] id: UBERON:0000355 name: pharyngeal mucosa namespace: uberon def: "A mucosa that is part of a pharynx [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of organ of pharynx" EXACT [OBOL:automatic] synonym: "mucosa of pharynx" EXACT [OBOL:automatic] synonym: "mucous membrane of pharynx" EXACT [FMA:55031, OBOL:automatic] synonym: "organ mucosa of pharynx" EXACT [OBOL:automatic] synonym: "pharynx mucosa" EXACT [OBOL:automatic] synonym: "pharynx mucosa of organ" EXACT [OBOL:automatic] synonym: "pharynx mucous membrane" EXACT [OBOL:automatic] synonym: "pharynx organ mucosa" EXACT [OBOL:automatic] synonym: "tunica mucosa pharyngis" EXACT [] xref: BTO:0001047 xref: EMAPA:26957 xref: FMA:55031 xref: MA:0003143 xref: SCTID:362121003 is_a: UBERON:0004785 ! respiratory system mucosa intersection_of: UBERON:0000344 ! mucosa intersection_of: BFO:0000050 UBERON:0001042 ! part of chordate pharynx relationship: BFO:0000050 UBERON:0001042 ! part of chordate pharynx [Term] id: UBERON:0000358 name: blastocyst namespace: uberon def: "The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm[GO]." [GO:0001824, Wikipedia:Blastocyst] xref: BTO:0001099 xref: CALOHA:TS-0076 xref: EFO:0000295 xref: EMAPA:36035 xref: EV:0100394 xref: FMA:83041 xref: GAID:1153 xref: MESH:D001755 xref: NCIT:C13739 xref: SCTID:308837009 xref: UMLS:C1281743 {source="ncithesaurus:Blastocyst"} xref: Wikipedia:Blastocyst is_a: UBERON:0002050 ! embryonic structure relationship: BFO:0000050 UBERON:0000307 ! part of blastula relationship: BFO:0000051 UBERON:0000087 ! has part inner cell mass relationship: BFO:0000051 UBERON:0000088 ! has part trophoblast relationship: RO:0002160 NCBITaxon:32525 ! only in taxon Theria relationship: RO:0002202 UBERON:0000085 ! develops from morula relationship: RO:0002491 UBERON:0000108 ! existence starts and ends during blastula stage property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/7/72/Blastocyst_English.svg" xsd:anyURI [Term] id: UBERON:0000361 name: red bone marrow namespace: uberon def: "The red vascular substance consisting of connective tissue and blood vessels, containing primitive blood cells, macrophages, megakaryocytes, and fat cells. Red marrow is found in the cavities of many bones. It manufactures and releases leukocytes and erythrocytes into the bloodstream." [http://medical-dictionary.thefreedictionary.com/red+marrow] synonym: "parenchymal red marrow" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "red marrow" EXACT [BTO:0001160] xref: BTO:0001160 xref: FMA:74595 xref: SCTID:328538003 xref: SCTID:75330005 is_a: UBERON:0002371 ! bone marrow intersection_of: UBERON:0002371 ! bone marrow intersection_of: RO:0002473 CL:0000988 ! composed primarily of hematopoietic cell relationship: BFO:0000050 UBERON:0012429 ! part of hematopoietic tissue relationship: RO:0002473 CL:0000988 ! composed primarily of hematopoietic cell [Term] id: UBERON:0000371 name: syncytiotrophoblast namespace: uberon def: "Extraembryonic cells of trophoblastic shell surrounding embryo, outside the cytotrophoblast layer, involved with implantation of the blastocyst by eroding extracellular matrix surrounding maternal endometrial cells at site of implantation, also contribute to villi. (dark staining, multinucleated)." [http://embryology.med.unsw.edu.au/Notes/placenta5.htm, Wikipedia:Syncytiotrophoblast] synonym: "syncytial trophoblast" EXACT [FMA:83040] synonym: "syntrophoblast layer" EXACT [ISBN:0073040584] xref: BTO:0001335 xref: EHDAA:129 xref: EHDAA:91 xref: EMAPA:16068 xref: FMA:83040 xref: NCIT:C33918 xref: SCTID:256965005 xref: UMLS:C1135936 {source="ncithesaurus:Syncytiotrophoblast"} xref: Wikipedia:Syncytiotrophoblast is_a: UBERON:0002050 {source="FMA"} ! embryonic structure relationship: BFO:0000050 UBERON:0004364 {source="EMAPA"} ! part of ectoplacental cone relationship: RO:0002473 CL:0000525 ! composed primarily of syncytiotrophoblast cell property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/d/df/Gray36.png" xsd:anyURI [Term] id: UBERON:0000377 name: maxillary nerve namespace: uberon def: "The sensory nerve subdivision of the trigeminal nerve that transmits sensory information from the palate, upper teeth and gingiva, the skin between the palpebral fissure and the mouth, and from the nasal cavity and maxillary sinuses." [MP:0009799, Wikipedia:Maxillary_nerve] synonym: "maxillary division [V2]" EXACT [FMA:52724] synonym: "maxillary division [Vb]" EXACT [FMA:52724] synonym: "maxillary division of fifth cranial nerve" EXACT [FMA:52724] synonym: "maxillary division of trigeminal nerve (Vb; V2)" EXACT [FMA:52724] synonym: "maxillary nerve [V2]" EXACT [FMA:52724] synonym: "maxillary nerve [Vb]" EXACT [FMA:52724] synonym: "nervus maxillaris (Vb; V2)" EXACT [FMA:52724] synonym: "ramus maxillaris (ramus V2)" EXACT [AAO:0010670] synonym: "second division of fifth cranial nerve" EXACT [FMA:52724] synonym: "second division of trigeminal nerve" EXACT [FMA:52724] synonym: "trigeminal V nerve maxillary division" EXACT [MA:0001103] xref: AAO:0010670 xref: BTO:0001378 xref: EHDAA2:0002087 xref: EMAPA:17799 xref: FMA:52724 xref: GAID:836 xref: MA:0001103 xref: MESH:D008442 xref: SCTID:280211001 xref: VHOG:0001346 xref: Wikipedia:Maxillary_nerve is_a: UBERON:0011779 ! nerve of head region relationship: RO:0002380 UBERON:0001645 ! branching part of trigeminal nerve property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/a/a9/Gray779.png" xsd:anyURI [Term] id: UBERON:0000379 name: tracheal mucosa namespace: uberon def: "A mucosa that is part of a respiratory airway." [OBOL:automatic] synonym: "mucosa of organ of trachea" EXACT [OBOL:automatic] synonym: "mucosa of organ of windpipe" EXACT [OBOL:automatic] synonym: "mucosa of trachea" EXACT [OBOL:automatic] synonym: "mucosa of windpipe" EXACT [OBOL:automatic] synonym: "mucous membrane of trachea" EXACT [FMA:7471, OBOL:automatic] synonym: "mucous membrane of windpipe" EXACT [OBOL:automatic] synonym: "organ mucosa of trachea" EXACT [OBOL:automatic] synonym: "organ mucosa of windpipe" EXACT [OBOL:automatic] synonym: "trachea mucosa" EXACT [OBOL:automatic] synonym: "trachea mucosa of organ" EXACT [OBOL:automatic] synonym: "trachea mucous membrane" EXACT [OBOL:automatic] synonym: "trachea organ mucosa" EXACT [OBOL:automatic] synonym: "tracheal mucous membrane" EXACT [FMA:7471] synonym: "tunica mucosa (tracheae)" EXACT [FMA:7471] synonym: "windpipe mucosa" EXACT [OBOL:automatic] synonym: "windpipe mucosa of organ" EXACT [OBOL:automatic] synonym: "windpipe mucous membrane" EXACT [OBOL:automatic] synonym: "windpipe organ mucosa" EXACT [OBOL:automatic] xref: BTO:0001390 xref: FMA:7471 xref: SCTID:660006 is_a: UBERON:0004785 ! respiratory system mucosa intersection_of: UBERON:0000344 ! mucosa intersection_of: BFO:0000050 UBERON:0001005 ! part of respiratory airway relationship: BFO:0000050 UBERON:0001005 ! part of respiratory airway [Term] id: UBERON:0000383 name: musculature of body namespace: uberon def: "The subdivision of the musculoskeletal system that consists of all the muscles of the body[VSAO, modified]." [VSAO:0000033] synonym: "muscle system" EXACT [] synonym: "muscle system of body" EXACT [] synonym: "muscular system" EXACT [FMA:72954] synonym: "musculature system" EXACT [BILA:0000088] synonym: "set of all muscles" EXACT [FMA:72954] synonym: "set of muscles of body" EXACT [FMA:72954] synonym: "vertebrate muscular system" EXACT [BTO:0001369] xref: AAO:0000307 xref: BILA:0000088 xref: BTO:0001369 xref: BTO:0001485 xref: EFO:0000801 xref: EMAPA:35578 xref: FMA:72954 xref: MA:0002888 xref: MAT:0000025 xref: MIAA:0000025 xref: VSAO:0000033 xref: XAO:0004042 is_a: UBERON:0011216 ! organ system subdivision intersection_of: UBERON:0011216 ! organ system subdivision intersection_of: RO:0002473 UBERON:0001015 ! composed primarily of musculature relationship: RO:0002160 NCBITaxon:6072 ! only in taxon Eumetazoa relationship: RO:0002215 GO:0003012 ! capable of muscle system process relationship: RO:0002473 UBERON:0001015 ! composed primarily of musculature [Term] id: UBERON:0000389 name: lens cortex namespace: uberon def: "Tissue that surrounds the lens nucleus." [http://www.thefreedictionary.com/lens+cortex] synonym: "cortex of lens" EXACT [FMA:58970] xref: BTO:0001632 xref: CALOHA:TS-0542 xref: FMA:58970 xref: MESH:D007904 xref: SCTID:280626006 is_a: UBERON:0000479 ! tissue is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0000479 ! tissue intersection_of: RO:0002221 UBERON:0000390 ! surrounds lens nucleus relationship: BFO:0000050 UBERON:0000965 ! part of lens of camera-type eye relationship: RO:0002202 UBERON:0005614 ! develops from lens anterior epithelium relationship: RO:0002221 UBERON:0000390 ! surrounds lens nucleus [Term] id: UBERON:0000390 name: lens nucleus namespace: uberon def: "The core of the crystalline lens, surrounded by the cortex." [BTO:0001633] synonym: "nucleus of lens" EXACT [FMA:58971] xref: BTO:0001633 xref: FMA:58971 xref: MESH:D007907 xref: SCTID:280628007 is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0034944 ! zone of organ intersection_of: UBERON:0034944 ! zone of organ intersection_of: RO:0002219 UBERON:0000389 ! surrounded by lens cortex relationship: BFO:0000050 UBERON:0000965 ! part of lens of camera-type eye relationship: RO:0002202 UBERON:0005614 ! develops from lens anterior epithelium relationship: RO:0002219 UBERON:0000389 ! surrounded by lens cortex [Term] id: UBERON:0000397 name: colonic epithelium namespace: uberon def: "An epithelium that is part of a colon [Automatically generated definition]." [OBOL:automatic] synonym: "colon epithelial tissue" EXACT [OBOL:automatic] synonym: "colon epithelium" EXACT [FMA:17302, OBOL:automatic] synonym: "epithelial tissue of colon" EXACT [OBOL:automatic] synonym: "epithelial tissue of large bowel" EXACT [OBOL:automatic] synonym: "epithelium of colon" EXACT [OBOL:automatic] synonym: "epithelium of large bowel" EXACT [OBOL:automatic] synonym: "large bowel epithelial tissue" EXACT [OBOL:automatic] synonym: "large bowel epithelium" EXACT [OBOL:automatic] synonym: "posterior intestine epithelium" EXACT [ZFA:0005128] xref: BTO:0001709 xref: CALOHA:TS-0163 xref: EMAPA:18941 xref: FMA:17302 xref: MA:0003195 xref: SCTID:42978003 xref: TAO:0005128 xref: ZFA:0005128 is_a: UBERON:0001278 ! epithelium of large intestine intersection_of: UBERON:0000483 ! epithelium intersection_of: BFO:0000050 UBERON:0001155 ! part of colon relationship: BFO:0000050 UBERON:0001155 ! part of colon [Term] id: UBERON:0000409 name: serous gland namespace: uberon def: "A gland in which the principal secretory cells are serous secreting cells." [http://orcid.org/0000-0002-6601-2165, http://www.siumed.edu/~dking2/intro/glands.htm] xref: BTO:0001837 xref: EMAPA:37950 {source="MA:th"} xref: FMA:62889 xref: Wikipedia:Serous_gland is_a: UBERON:0002365 ! exocrine gland intersection_of: UBERON:0002365 ! exocrine gland intersection_of: BFO:0000051 CL:0000313 ! has part serous secreting cell relationship: BFO:0000051 UBERON:0013232 ! has part serous acinus relationship: RO:0003000 UBERON:0007794 ! produces secretion of serous gland property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/c/c0/Gray1021.png" xsd:anyURI [Term] id: UBERON:0000414 name: mucous gland namespace: uberon def: "A gland in which the principal secretory cells are mucus secreting cells." [http://orcid.org/0000-0002-6601-2165, http://www.siumed.edu/~dking2/intro/glands.htm] xref: AAO:0010601 xref: BTO:0001979 xref: EMAPA:37913 {source="MA:th"} xref: FMA:62888 xref: Wikipedia:Mucous_gland is_a: UBERON:0002365 ! exocrine gland intersection_of: UBERON:0002365 ! exocrine gland intersection_of: BFO:0000051 CL:0000319 ! has part mucus secreting cell relationship: BFO:0000051 CL:0000319 ! has part mucus secreting cell relationship: RO:0002215 GO:0070254 ! capable of mucus secretion relationship: RO:0003000 UBERON:0000912 ! produces mucus property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/c/c0/Gray1021.png" xsd:anyURI [Term] id: UBERON:0000415 name: artery wall namespace: uberon def: "An anatomical wall that is part of an artery [Automatically generated definition]." [OBOL:automatic] synonym: "arterial wall" EXACT [FMA:14155] synonym: "wall of artery" EXACT [FMA:14155] xref: BTO:0002009 xref: FMA:14155 xref: galen:ArterialWall is_a: UBERON:0035965 ! wall of blood vessel intersection_of: UBERON:0000060 ! anatomical wall intersection_of: BFO:0000050 UBERON:0001637 ! part of artery relationship: BFO:0000050 UBERON:0001637 ! part of artery [Term] id: UBERON:0000440 name: trabecula namespace: uberon def: "A small, often microscopic, tissue element in the form of a small beam, strut or rod, generally having a mechanical function, and usually but not necessarily composed of dense collagenous tissue. On histological section, a trabecula can look like a septum, but in three dimensions they are topologically distinct, with trabeculae being roughly rod or pillar-shaped and septa being sheet-like. Trabeculae are usually composed of dense fibrous tissue, i.e. mainly of collagen, and in most cases provide mechanical strengthening or stiffening to a soft solid organ, such as the spleen. They can be composed of other materials, such as bone or muscle[WP]." [GO:0060343, Wikipedia:Trabecula] xref: BTO:0002501 xref: FMA:85273 xref: Wikipedia:Trabecula is_a: UBERON:0000064 ! organ part relationship: BFO:0000051 UBERON:0002384 ! has part connective tissue relationship: RO:0000086 PATO:0001873 ! has quality cylindrical [Term] id: UBERON:0000442 name: right testicular vein namespace: uberon def: "A vein that drains the left pampiniform plexus and empties into the left renal vein." [Dorlands_Medical_Dictionary:MerckSource] synonym: "right spermatic vein" EXACT [MA:0002220] synonym: "vena testicularis (adrenalis) dextra" EXACT [FMA:14341] xref: BTO:0002679 xref: EMAPA:37383 {source="MA:th"} xref: FMA:14341 xref: MA:0002220 xref: NCIT:C52697 xref: SCTID:53500001 is_a: UBERON:0001144 ! testicular vein intersection_of: UBERON:0001144 ! testicular vein intersection_of: RO:0002179 UBERON:0004534 ! drains right testis relationship: BSPO:0000120 UBERON:0000468 ! in left side of multicellular organism relationship: RO:0002170 UBERON:0001142 ! connected to left renal vein relationship: RO:0002179 UBERON:0004534 ! drains right testis [Term] id: UBERON:0000443 name: left testicular vein namespace: uberon def: "A vein that drains the right pampiniform plexus and empties into the inferior vena cava." [Dorlands_Medical_Dictionary:MerckSource] synonym: "left spermatic vein" EXACT [MA:0002219] xref: BTO:0002680 xref: EMAPA:37167 {source="MA:th"} xref: FMA:14345 xref: MA:0002219 xref: NCIT:C52696 xref: SCTID:90988008 is_a: UBERON:0001144 ! testicular vein intersection_of: UBERON:0001144 ! testicular vein intersection_of: RO:0002179 UBERON:0004533 ! drains left testis relationship: BSPO:0000120 UBERON:0000468 ! in left side of multicellular organism relationship: RO:0002170 UBERON:0001142 ! connected to left renal vein relationship: RO:0002179 UBERON:0004533 ! drains left testis [Term] id: UBERON:0000456 name: secretion of exocrine gland namespace: uberon def: "A portion of organism substance that is produced by exocrine glands." [http://orcid.org/0000-0002-6601-2165] synonym: "bodily secretion" EXACT [MESH:D012634] synonym: "exocrine gland fluid/secretion" EXACT [MA:0002504] synonym: "secreted substance" EXACT [] xref: AEO:0001005 xref: BTO:0002977 xref: BTO:0002979 xref: EMAPA:36535 xref: FMA:9675 xref: galen:Secretion xref: MA:0002504 xref: MESH:D012634 xref: NCIT:C34062 xref: UMLS:C1516992 {source="ncithesaurus:Exocrine_Gland_Fluid_or_Secretion"} is_a: UBERON:0000463 ! organism substance intersection_of: UBERON:0000463 ! organism substance intersection_of: RO:0003001 UBERON:0002365 ! produced by exocrine gland relationship: RO:0003001 UBERON:0002365 ! produced by exocrine gland [Term] id: UBERON:0000459 name: uterine wall namespace: uberon def: "An anatomical wall that is part of a uterus [Automatically generated definition]." [OBOL:automatic] synonym: "anatomical wall of uterus" EXACT [OBOL:automatic] synonym: "uterus anatomical wall" EXACT [OBOL:automatic] synonym: "uterus wall" EXACT [OBOL:automatic] synonym: "wall of uterus" EXACT [OBOL:automatic] xref: BTO:0003083 xref: FMA:17560 xref: SCTID:245485002 is_a: UBERON:0000060 ! anatomical wall is_a: UBERON:0005156 ! reproductive structure intersection_of: UBERON:0000060 ! anatomical wall intersection_of: BFO:0000050 UBERON:0000995 ! part of uterus relationship: BFO:0000050 UBERON:0000995 ! part of uterus [Term] id: UBERON:0000463 name: organism substance namespace: uberon def: "Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body." [http://orcid.org/0000-0001-9114-8737] synonym: "body fluid or substance" EXACT [MA:0002450] synonym: "body substance" EXACT [FMA:9669] synonym: "organism substance" EXACT [CARO:0000004] synonym: "portion of body substance" EXACT [FMA:9669] synonym: "portion of organism substance" EXACT [ZFA:0001487] xref: AAO:0010839 xref: AEO:0000004 xref: BILA:0000004 xref: CALOHA:TS-2101 xref: CARO:0000004 xref: EHDAA2:0003004 xref: EMAPA:35178 xref: FMA:9669 xref: galen:BodySubstance xref: HAO:0000004 xref: MA:0002450 xref: NCIT:C13236 xref: SPD:0000008 xref: TAO:0001487 xref: TGMA:0001824 xref: VHOG:0001726 xref: XAO:0004001 xref: ZFA:0001487 is_a: UBERON:0000465 ! material anatomical entity relationship: BFO:0000050 UBERON:0000468 ! part of multicellular organism relationship: RO:0000086 PATO:0002198 ! has quality quality of a substance [Term] id: UBERON:0000464 name: anatomical space namespace: uberon def: "Non-material anatomical entity of three dimensions, that is generated by morphogenetic or other physiologic processes; is surrounded by one or more anatomical structures; contains one or more organism substances or anatomical structures." [http://orcid.org/0000-0001-9114-8737] synonym: "lumen space" EXACT [] xref: AAO:0010110 xref: AEO:0000005 xref: BILA:0000005 xref: CARO:0000005 xref: EHDAA2:0003005 xref: FMA:5897 xref: HAO:0000005 xref: NCIT:C94478 xref: TAO:0001668 xref: TGMA:0001825 xref: UMLS:C0524461 {source="ncithesaurus:Lumen_Space"} xref: VHOG:0001728 xref: XAO:0003190 xref: ZFA:0001643 is_a: UBERON:0000466 ! immaterial anatomical entity relationship: RO:0002219 UBERON:0000061 ! surrounded by anatomical structure [Term] id: UBERON:0000465 name: material anatomical entity namespace: uberon def: "Anatomical entity that has mass." [http://orcid.org/0000-0001-9114-8737] xref: AAO:0010264 xref: AEO:0000006 xref: BILA:0000006 xref: CARO:0000006 xref: EHDAA2:0003006 xref: FMA:67165 xref: HAO:0000006 xref: TAO:0001836 xref: TGMA:0001826 xref: VHOG:0001721 is_a: BFO:0000040 ! material entity is_a: UBERON:0001062 ! anatomical entity disjoint_from: UBERON:0000466 ! immaterial anatomical entity [Term] id: UBERON:0000466 name: immaterial anatomical entity namespace: uberon def: "Anatomical entity that has no mass." [http://orcid.org/0000-0001-9114-8737] synonym: "immaterial physical anatomical entity" EXACT [FMA:67112] xref: AAO:0010265 xref: AEO:0000007 xref: BILA:0000007 xref: CARO:0000007 xref: EHDAA2:0003007 xref: FMA:67112 xref: HAO:0000007 xref: TAO:0001835 xref: TGMA:0001827 xref: VHOG:0001727 is_a: BFO:0000141 ! immaterial entity is_a: UBERON:0001062 ! anatomical entity [Term] id: UBERON:0000467 name: anatomical system namespace: uberon def: "Multicellular, connected anatomical structure that has multiple organs as parts and whose parts work together to achieve some shared function." [CARO:0000011] synonym: "body system" EXACT [BIRNLEX:14] synonym: "connected anatomical system" EXACT [CARO:0000011] synonym: "organ system" EXACT [] xref: AAO:0000007 xref: AEO:0000011 xref: BILA:0000011 xref: BIRNLEX:14 xref: BSA:0000049 xref: CALOHA:TS-2088 xref: CARO:0000011 xref: EHDAA2:0003011 xref: EHDAA:392 xref: EMAPA:16103 xref: EV:0100000 xref: FMA:7149 xref: galen:AnatomicalSystem xref: HAO:0000011 xref: MA:0000003 xref: NCIT:C12919 xref: SCTID:278195005 xref: TAO:0001439 xref: TGMA:0001831 xref: UMLS:C0460002 {source="ncithesaurus:Organ_System"} xref: VHOG:0001725 xref: WBbt:0005746 xref: WBbt:0005763 xref: Wikipedia:Organ_system xref: XAO:0003002 xref: ZFA:0001439 is_a: UBERON:0000061 ! anatomical structure relationship: BFO:0000050 UBERON:0000468 ! part of multicellular organism relationship: BFO:0000051 UBERON:0000062 ! has part organ relationship: RO:0002496 UBERON:0000111 {gci_filler="NCBITaxon:6072", gci_relation="RO:0002162"} ! existence starts during or after organogenesis stage [Term] id: UBERON:0000468 name: multicellular organism namespace: uberon def: "Anatomical structure that is an individual member of a species and consists of more than one cell." [CARO:0000012, http://orcid.org/0000-0001-9114-8737, Wikipedia:Multi-cellular_organism] synonym: "multi-cellular organism" EXACT [CARO:0000012] xref: AAO:0010026 xref: AEO:0000191 xref: BILA:0000012 xref: BIRNLEX:18 xref: BSA:0000038 xref: BTO:0000042 xref: CARO:0000012 xref: EFO:0002906 xref: EHDAA2:0003103 xref: EHDAA2:0003191 xref: EHDAA:1 xref: EMAPA:25765 xref: EV:0100016 xref: FMA:256135 xref: galen:Organism xref: HAO:0000012 xref: NCIT:C13041 xref: ncithesaurus:Whole_Organism xref: SCTID:243928005 xref: TADS:0000001 xref: TAO:0001094 xref: TGMA:0001832 xref: VHOG:0000671 xref: WBbt:0007833 xref: Wikipedia:Multi-cellular_organism xref: XAO:0003004 xref: ZFA:0001094 is_a: UBERON:0010000 ! multicellular anatomical structure [Term] id: UBERON:0000471 name: compound organ component namespace: uberon def: "Multi-tissue structure that is part of a compound organ." [CARO:0000019, http://orcid.org/0000-0001-9114-8737] xref: AAO:0010017 xref: AEO:0000019 xref: BILA:0000019 xref: CARO:0000019 xref: EHDAA2:0003019 xref: HAO:0000019 xref: TAO:0001489 xref: TGMA:0001835 xref: XAO:0003039 xref: ZFA:0001489 is_a: UBERON:0000481 ! multi-tissue structure relationship: BFO:0000050 UBERON:0003103 ! part of compound organ property_value: IAO:0000232 "this class was introduced for consistency with CARO, however, it has yet to be used in this or other ontologies. It may be retired in the future" xsd:string [Term] id: UBERON:0000473 name: testis namespace: uberon def: "A gonad of a male animal. A gonad produces and releases sperm." [http://orcid.org/0000-0002-6601-2165] synonym: "gonad of male genitalia" EXACT [OBOL:automatic] synonym: "gonad of male reproductive system" EXACT [OBOL:automatic] synonym: "male gonad" EXACT [OBOL:automatic] synonym: "testicle" EXACT [FMA:7210] xref: AAO:0000606 xref: BILA:0000124 xref: BSA:0000085 xref: BTO:0001363 xref: CALOHA:TS-1030 xref: EFO:0000984 xref: EHDAA2:0002007 xref: EHDAA:8146 xref: EMAPA:17972 xref: EV:0100102 xref: FMA:7210 xref: GAID:396 xref: galen:Testis xref: HAO:0001007 xref: MA:0000411 xref: MAT:0000132 xref: MESH:D013737 xref: MIAA:0000132 xref: NCIT:C12412 xref: SCTID:181431007 xref: TAO:0000598 xref: UMLS:C0039597 {source="ncithesaurus:Testis"} xref: VHOG:0000252 xref: WBbt:0006794 xref: Wikipedia:Testis xref: XAO:0000157 xref: ZFA:0000598 is_a: UBERON:0000991 ! gonad is_a: UBERON:0003135 ! male reproductive organ intersection_of: UBERON:0000991 ! gonad intersection_of: BFO:0000050 UBERON:0000079 ! part of male reproductive system disjoint_from: UBERON:0000992 ! ovary disjoint_from: UBERON:0009117 ! indifferent gonad relationship: RO:0002202 UBERON:0009117 ! develops from indifferent gonad property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/c/c3/Gray1144.png" xsd:anyURI [Term] id: UBERON:0000474 name: female reproductive system namespace: uberon def: "The organs and associated structures associated with bearing offspring in a female animal." [http://orcid.org/0000-0002-6601-2165, MP:0001119, Wikipedia:Female_genitalia] synonym: "female organism genitalia" EXACT [OBOL:automatic] synonym: "female organism reproductive system" EXACT [OBOL:automatic] synonym: "genitalia of female organism" EXACT [OBOL:automatic] synonym: "reproductive system of female organism" EXACT [OBOL:automatic] xref: BTO:0000083 xref: CALOHA:TS-1303 xref: EFO:0000969 xref: EHDAA2:0000506 xref: EHDAA:8116 xref: EMAPA:17959 xref: EV:0100110 xref: FMA:45663 xref: GAID:364 xref: HAO:0000324 xref: MA:0000381 xref: MESH:D005836 xref: MIAA:0000028 xref: NCIT:C12402 xref: SCTID:361386004 xref: TGMA:0000635 xref: UMLS:C0700038 {source="ncithesaurus:Female_Reproductive_System"} xref: VHOG:0000726 xref: Wikipedia:Female_genitalia xref: WikipediaCategory:Female_reproductive_system xref: XAO:0000156 is_a: UBERON:0000990 ! reproductive system intersection_of: UBERON:0000990 ! reproductive system intersection_of: BFO:0000050 UBERON:0003100 ! part of female organism relationship: BFO:0000050 UBERON:0003100 ! part of female organism property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/6/68/Scheme_female_reproductive_system-en.svg" xsd:anyURI [Term] id: UBERON:0000475 name: organism subdivision namespace: uberon def: "Anatomical structure which is a subdivision of a whole organism, consisting of components of multiple anatomical systems, largely surrounded by a contiguous region of integument." [CARO:0000032, CARO:DOS, http://orcid.org/0000-0001-9114-8737] synonym: "anatomic region" EXACT [MA:0002433] xref: AAO:0010053 xref: AEO:0000032 xref: BILA:0000032 xref: BIRNLEX:7 xref: CALOHA:TS-2084 xref: CARO:0000032 xref: EFO:0000808 xref: EHDAA2:0003032 xref: EMAPA:36031 xref: FMA:7153 xref: galen:BodyPart xref: HAO:0000032 xref: MA:0002433 xref: MAT:0000293 xref: MESH:D001829 xref: MIAA:0000293 xref: NCIT:C32221 xref: TAO:0001308 xref: TGMA:0001840 xref: UMLS:C0229962 {source="ncithesaurus:Body_Part"} xref: VHOG:0001758 xref: Wikipedia:Body_part xref: XAO:0003013 xref: ZFA:0001308 is_a: UBERON:0010000 {source="CARO"} ! multicellular anatomical structure relationship: BFO:0000050 UBERON:0000468 ! part of multicellular organism relationship: BFO:0000051 UBERON:0000075 {gci_filler="NCBITaxon:7742", gci_relation="BFO:0000050"} ! has part subdivision of skeletal system relationship: BFO:0000051 UBERON:0034929 {gci_filler="NCBITaxon:7742", gci_relation="BFO:0000050"} ! has part external soft tissue zone relationship: RO:0002131 UBERON:0001009 {gci_filler="NCBITaxon:33213", gci_relation="RO:0002162"} ! overlaps circulatory system relationship: RO:0002131 UBERON:0001015 {gci_filler="NCBITaxon:6072", gci_relation="RO:0002162"} ! overlaps musculature relationship: RO:0002131 UBERON:0001016 {gci_filler="NCBITaxon:6072", gci_relation="RO:0002162"} ! overlaps nervous system relationship: RO:0002131 UBERON:0001434 {gci_filler="NCBITaxon:33213", gci_relation="RO:0002162"} ! overlaps skeletal system relationship: RO:0002131 UBERON:0002416 {gci_filler="NCBITaxon:6072", gci_relation="RO:0002162"} ! overlaps integumental system [Term] id: UBERON:0000476 name: acellular anatomical structure namespace: uberon def: "Anatomical structure that consists of cell parts and cell substances and together does not constitute a cell or a tissue." [http://orcid.org/0000-0001-9114-8737] xref: AAO:0010268 xref: AEO:0000040 xref: BILA:0000040 xref: CARO:0000040 xref: EHDAA2:0003040 xref: FMA:63863 xref: HAO:0000040 xref: TAO:0000382 xref: TGMA:0001841 xref: XAO:0003162 xref: ZFA:0000382 is_a: UBERON:0000061 ! anatomical structure disjoint_from: UBERON:0010000 {source="CARO"} ! multicellular anatomical structure [Term] id: UBERON:0000477 name: anatomical cluster namespace: uberon def: "Anatomical group whose component anatomical structures lie in close proximity to each other." [FBbt:00007277] xref: VHOG:0001737 is_a: UBERON:0034923 ! disconnected anatomical group [Term] id: UBERON:0000478 name: extraembryonic structure namespace: uberon def: "A multicellular anatomical structure that is associated with an embryo and derived from the zygote from which it develops, but which does not contribute to the embryo proper or to structures that are part of the same organism after embryogenesis." [CARO:DOS, http://orcid.org/0000-0001-9114-8737, https://cedar.bio.indiana.edu/trac/env/ontologies/ticket/279] synonym: "extra-embryonic structure" EXACT [] xref: AAO:0010020 xref: AEO:0000042 xref: BILA:0000042 xref: CALOHA:TS-2119 xref: CARO:0000042 xref: EHDAA2:0003042 xref: EHDAA:46 xref: FMA:85537 xref: HAO:0000042 xref: NCIT:C34055 xref: SCTID:314908006 xref: TAO:0000020 xref: TGMA:0001843 xref: UMLS:C1282438 {source="ncithesaurus:Extraembryonic_Structure"} xref: VHOG:0000292 xref: XAO:0004005 xref: ZFA:0000020 is_a: UBERON:0005423 ! developing anatomical structure intersection_of: UBERON:0005423 ! developing anatomical structure intersection_of: BFO:0000050 UBERON:0016887 ! part of entire extraembryonic component relationship: BFO:0000050 UBERON:0016887 ! part of entire extraembryonic component relationship: RO:0002491 UBERON:0000068 {gci_filler="NCBITaxon:6072", gci_relation="RO:0002162"} ! existence starts and ends during embryo stage [Term] id: UBERON:0000479 name: tissue namespace: uberon def: "Multicellular anatomical structure that consists of many cells of one or a few types, arranged in an extracellular matrix such that their long-range organisation is at least partly a repetition of their short-range organisation." [CARO:0000043] synonym: "portion of tissue" EXACT [CARO:0000043] synonym: "tissue portion" EXACT [] xref: AAO:0000607 xref: AAO:0010054 xref: AEO:0000043 xref: BILA:0000043 xref: BIRNLEX:19 xref: CALOHA:TS-2090 xref: CARO:0000043 xref: EHDAA2:0003043 xref: EMAPA:35868 xref: FMA:9637 xref: galen:Tissue xref: HAO:0000043 xref: MA:0003002 xref: MESH:D014024 xref: NCIT:C12801 xref: TAO:0001477 xref: TGMA:0001844 xref: UMLS:C0040300 {source="ncithesaurus:Tissue"} xref: VHOG:0001757 xref: WBbt:0005729 xref: XAO:0003040 xref: ZFA:0001477 is_a: UBERON:0010000 {source="CARO"} ! multicellular anatomical structure relationship: BFO:0000050 UBERON:0000468 ! part of multicellular organism relationship: BFO:0000051 GO:0031012 ! has part extracellular matrix [Term] id: UBERON:0000481 name: multi-tissue structure namespace: uberon def: "Anatomical structure that has as its parts two or more portions of tissue of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona-fide boundaries from other distinct structural units of different types." [CARO:0000055, http://orcid.org/0000-0001-9114-8737] xref: AAO:0010048 xref: AEO:0000055 xref: BILA:0000055 xref: CARO:0000055 xref: EHDAA2:0003055 xref: HAO:0000055 xref: TAO:0001488 xref: TGMA:0001847 xref: VHOG:0001762 xref: XAO:0003037 xref: ZFA:0001488 is_a: UBERON:0010000 {source="CARO"} ! multicellular anatomical structure relationship: BFO:0000050 NCBITaxon:6072 {gci_filler="NCBITaxon:6072", gci_relation="RO:0002162"} ! part of Eumetazoa relationship: BFO:0000051 UBERON:0000479 ! has part tissue [Term] id: UBERON:0000483 name: epithelium namespace: uberon def: "Portion of tissue, that consists of one or more layers of epithelial cells connected to each other by cell junctions and which is underlain by a basal lamina. Examples: simple squamous epithelium, glandular cuboidal epithelium, transitional epithelium, myoepithelium[CARO]." [http://orcid.org/0000-0001-9114-8737, Wikipedia:Epithelium] synonym: "epithelial tissue" EXACT [] synonym: "portion of epithelium" EXACT [FMA:9639] xref: AAO:0000144 xref: AAO:0010055 xref: AEO:0000066 xref: BILA:0000066 xref: BTO:0000416 xref: CALOHA:TS-0288 xref: CARO:0000066 xref: EHDAA2:0003066 xref: EMAPA:32738 xref: FMA:9639 xref: GAID:402 xref: HAO:0000066 xref: MA:0003060 xref: MESH:D004848 xref: NCIT:C12710 xref: SCTID:31610004 xref: TAO:0001486 xref: UMLS:C0014609 {source="ncithesaurus:Epithelium"} xref: VHOG:0000387 xref: Wikipedia:Epithelium xref: XAO:0003045 xref: ZFA:0001486 is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000479 ! tissue intersection_of: UBERON:0000479 ! tissue intersection_of: RO:0002473 CL:0000066 ! composed primarily of epithelial cell union_of: UBERON:0000486 ! multilaminar epithelium union_of: UBERON:0000490 ! unilaminar epithelium relationship: BFO:0000051 GO:0005911 ! has part cell-cell junction relationship: BFO:0000051 UBERON:0005769 ! has part basement membrane of epithelium relationship: RO:0002160 NCBITaxon:33208 {source="http://palaeos.com/metazoa/porifera/homoscleromorpha.html"} ! only in taxon Metazoa relationship: RO:0002473 CL:0000066 ! composed primarily of epithelial cell property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/8/8f/Illu_epithelium.jpg" xsd:anyURI [Term] id: UBERON:0000484 name: simple cuboidal epithelium namespace: uberon def: "Unilaminar epithelium that consists of a single layer of cuboidal cells." [http://orcid.org/0000-0001-9114-8737, Wikipedia:Simple_cuboidal_epithelium] synonym: "epithelium simplex cuboideum" EXACT [] xref: AAO:0010064 xref: AEO:0000067 xref: BILA:0000067 xref: CARO:0000067 xref: EHDAA2:0003067 xref: FMA:45566 xref: HAO:0000067 xref: NCIT:C33553 xref: TAO:0001497 xref: UMLS:C0836134 {source="ncithesaurus:Simple_Cuboidal_Epithelium"} xref: Wikipedia:Simple_cuboidal_epithelium xref: XAO:0004009 xref: ZFA:0001497 is_a: UBERON:0000490 ! unilaminar epithelium is_a: UBERON:0010077 ! cuboidal epithelium property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/d/d0/Gray1133.png" xsd:anyURI [Term] id: UBERON:0000485 name: simple columnar epithelium namespace: uberon def: "Unilaminar epithelium, which consists of a single layer of columnar cells. Examples: ciliated columnar epithelium, gastric epithelium, microvillus columnar epithelium.[FMA]." [FMA:FMA, http://orcid.org/0000-0001-9114-8737, Wikipedia:Simple_columnar_epithelium] synonym: "epithelium simplex columnare" EXACT [] synonym: "simple columnar epithelium" EXACT [] xref: AAO:0010063 xref: AEO:0000068 xref: BILA:0000068 xref: CARO:0000068 xref: EHDAA2_RETIRED:0003068 xref: FMA:45567 xref: HAO:0000068 xref: NCIT:C33552 xref: SCTID:32210007 xref: TAO:0001496 xref: UMLS:C0836135 {source="ncithesaurus:Simple_Columnar_Epithelium"} xref: Wikipedia:Simple_columnar_epithelium xref: XAO:0004008 xref: ZFA:0001496 is_a: UBERON:0000490 ! unilaminar epithelium is_a: UBERON:0012274 ! columnar epithelium property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/8/8b/Gray1059.png" xsd:anyURI [Term] id: UBERON:0000486 name: multilaminar epithelium namespace: uberon def: "Epithelium which consists of more than one layer of epithelial cells that may or may not be in contact with a basement membrane. Examples: keratinized stratified squamous epithelium, ciliated stratified columnar epithelium.[FMA]." [FMA:FMA, http://orcid.org/0000-0001-9114-8737, Wikipedia:Stratified_epithelium] synonym: "stratified epithelium" EXACT [] xref: AAO:0010059 xref: AEO:0000069 xref: BILA:0000069 xref: BTO:0002074 xref: CARO:0000069 xref: EHDAA2:0003069 xref: FMA:45562 xref: HAO:0000069 xref: NCIT:C33622 xref: SCTID:309044005 xref: TAO:0001494 xref: UMLS:C0682575 {source="ncithesaurus:Stratified_Epithelium"} xref: Wikipedia:Stratified_epithelium xref: XAO:0004006 xref: ZFA:0001494 is_a: UBERON:0000483 ! epithelium [Term] id: UBERON:0000487 name: simple squamous epithelium namespace: uberon def: "Unilaminar epithelium which consists of a single layer of squamous cells. Examples: pulmonary alveolar epithelium, endothelium.[FMA]." [FMA:45565, http://orcid.org/0000-0001-9114-8737, Wikipedia:Simple_squamous_epithelium] synonym: "epithelium simplex squamosum" EXACT [] xref: AAO:0010066 xref: AEO:0000070 xref: BILA:0000070 xref: BTO:0002073 xref: CARO:0000070 xref: EHDAA2:0003070 xref: FMA:45565 xref: HAO:0000070 xref: NCIT:C13178 xref: TAO:0001498 xref: UMLS:C0836133 {source="ncithesaurus:Simple_Squamous_Epithelium"} xref: Wikipedia:Simple_squamous_epithelium xref: XAO:0004010 xref: ZFA:0001498 is_a: UBERON:0000490 ! unilaminar epithelium is_a: UBERON:0006914 ! squamous epithelium intersection_of: UBERON:0000490 ! unilaminar epithelium intersection_of: BFO:0000051 CL:0000076 ! has part squamous epithelial cell property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/8/8f/Illu_epithelium.jpg" xsd:anyURI [Term] id: UBERON:0000488 name: atypical epithelium namespace: uberon def: "Epithelium that consists of epithelial cells not arranged in one ore more layers." [http://orcid.org/0000-0001-9114-8737] synonym: "heterogenous epithelium" EXACT [] xref: AAO:0010057 xref: AEO:0000071 xref: BILA:0000071 xref: CARO:0000071 xref: EHDAA2:0003071 xref: FMA:61741 xref: HAO:0000071 xref: TAO:0001493 xref: XAO:0004004 xref: ZFA:0001493 is_a: UBERON:0000483 ! epithelium [Term] id: UBERON:0000489 name: cavitated compound organ namespace: uberon def: "Compound organ that contains one or more macroscopic anatomical spaces." [http://orcid.org/0000-0001-9114-8737] synonym: "cavitated organ" EXACT [FMA:55671] xref: AAO:0010016 xref: AEO:0000072 xref: BILA:0000072 xref: CARO:0000072 xref: EHDAA2:0003072 xref: FMA:55671 xref: HAO:0000072 xref: TAO:0001490 xref: TGMA:0001857 xref: VHOG:0001730 xref: XAO:0003165 xref: ZFA:0001490 is_a: UBERON:0003103 ! compound organ intersection_of: UBERON:0003103 ! compound organ intersection_of: BFO:0000051 UBERON:0002553 ! has part anatomical cavity relationship: BFO:0000051 UBERON:0002553 ! has part anatomical cavity property_value: IAO:0000232 "this class was introduced for consistency with CARO, however, it has yet to be used in this or other ontologies. It may be retired in the future" xsd:string [Term] id: UBERON:0000490 name: unilaminar epithelium namespace: uberon def: "Epithelium which consists of a single layer of epithelial cells. Examples: endothelium, mesothelium, glandular squamous epithelium.[FMA]." [FMA:45561, http://orcid.org/0000-0001-9114-8737] synonym: "simple epithelium" EXACT [FMA:45561] xref: AAO:0010062 xref: AEO:0000073 xref: BILA:0000073 xref: BTO:0002073 xref: CARO:0000073 xref: EHDAA2:0003073 xref: FMA:45561 xref: HAO:0000073 xref: NCIT:C33554 xref: SCTID:309043004 xref: TAO:0001495 xref: UMLS:C0682574 {source="ncithesaurus:Simple_Epithelium"} xref: XAO:0004007 xref: ZFA:0001495 is_a: UBERON:0000483 ! epithelium [Term] id: UBERON:0000912 name: mucus namespace: uberon def: "Mucus is a bodily fluid consisting of a slippery secretion of the lining of the mucous membranes in the body. It is a viscous colloid containing antiseptic enzymes (such as lysozyme) and immunoglobulins. Mucus is produced by goblet cells in the mucous membranes that cover the surfaces of the membranes. It is made up of mucins and inorganic salts suspended in water." [Wikipedia:Mucus] xref: CALOHA:TS-2144 xref: ENVO:02000040 xref: FMA:66938 xref: GAID:1164 xref: galen:Mucus xref: MESH:D009093 xref: NCIT:C13259 xref: UMLS:C0026727 {source="ncithesaurus:Mucus"} xref: Wikipedia:Mucus is_a: UBERON:0000456 ! secretion of exocrine gland is_a: UBERON:0006314 ! bodily fluid relationship: BFO:0000051 CHEBI:37395 ! has part mucopolysaccharide relationship: RO:0000086 PATO:0000998 ! has quality viscous relationship: RO:0003001 UBERON:0000344 ! produced by mucosa [Term] id: UBERON:0000915 name: thoracic segment of trunk namespace: uberon def: "Subdivision of trunk that lies between the head and the abdomen." [http://orcid.org/0000-0002-6601-2165] synonym: "thorax" EXACT [MA:0000022] xref: EMAPA:35862 xref: FMA:259209 xref: MA:0000022 xref: SCTID:302551006 xref: Wikipedia:Thorax is_a: UBERON:0009569 {source="FMA"} ! subdivision of trunk is_a: UBERON:0011676 ! subdivision of organism along main body axis intersection_of: UBERON:0011676 ! subdivision of organism along main body axis intersection_of: RO:0002551 UBERON:0014477 ! has skeleton thoracic skeleton relationship: RO:0002551 UBERON:0014477 ! has skeleton thoracic skeleton property_value: IAO:0000232 "note that we use the slightly verbose term 'thoracic segment of trunk' to avoid confusuon with insect thorax. todo - taxonomic constraints. Also, in FMA 'thorax' is a synonym for chest" xsd:string [Term] id: UBERON:0000916 name: abdomen namespace: uberon def: "The subdivision of the vertebrate body between the thorax and pelvis. The ventral part of the abdomen contains the abdominal cavity and visceral organs. The dorsal part includes the abdominal section of the vertebral column." [http://orcid.org/0000-0002-6601-2165] synonym: "abdominopelvic region" EXACT [FMA:9577] synonym: "abdominopelvis" EXACT [FMA:9577] xref: BTO:0000020 xref: CALOHA:TS-0001 xref: EFO:0000968 xref: EMAPA:35102 xref: EV:0100011 xref: FMA:9577 xref: GAID:16 xref: galen:Abdomen xref: MA:0000029 xref: MAT:0000298 xref: MESH:D000005 xref: MIAA:0000298 xref: SCTID:302553009 xref: Wikipedia:Abdomen is_a: UBERON:0009569 ! subdivision of trunk relationship: BFO:0000050 UBERON:0002417 {source="MA"} ! part of abdominal segment of trunk relationship: RO:0002160 NCBITaxon:7742 ! only in taxon Vertebrata [Term] id: UBERON:0000922 name: embryo namespace: uberon def: "Anatomical entity that comprises the organism in the early stages of growth and differentiation that are characterized by cleavage, the laying down of fundamental tissues, and the formation of primitive organs and organ systems. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant." [BTO:0000379, FB:FBrf0039741, FB:FBrf0041814, GO:0009790, Wikipedia:Embryo] synonym: "embryonic organism" EXACT [BILA:0000056] xref: AAO:0011035 xref: AEO:0000169 xref: BILA:0000056 xref: BSA:0000039 xref: BTO:0000379 xref: CALOHA:TS-0229 xref: EFO:0001367 xref: EHDAA2:0000002 xref: EHDAA2_RETIRED:0003236 xref: EHDAA:38 xref: EMAPA:16039 xref: FMA:69068 xref: GAID:963 xref: http://neurolex.org/wiki/Category\:Embryonic_organism xref: MAT:0000226 xref: MESH:D004622 xref: MIAA:0000019 xref: NCIT:C28147 xref: OGEM:000001 xref: SCTID:57991002 xref: UMLS:C0013935 {source="ncithesaurus:Embryo"} xref: VHOG:0001766 xref: Wikipedia:Embryo xref: XAO:0000113 xref: ZFA:0000103 is_a: UBERON:0000468 ! multicellular organism intersection_of: UBERON:0000468 ! multicellular organism intersection_of: RO:0002489 UBERON:0000068 ! existence starts with embryo stage intersection_of: RO:0002493 UBERON:0000068 ! existence ends with embryo stage relationship: RO:0002489 UBERON:0000068 ! existence starts with embryo stage relationship: RO:0002493 UBERON:0000068 ! existence ends with embryo stage property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/2/2d/Wrinkledfrog_embryos.jpg" xsd:anyURI [Term] id: UBERON:0000923 name: germ layer namespace: uberon def: "A layer of cells produced during the process of gastrulation during the early development of the animal embryo, which is distinct from other such layers of cells, as an early step of cell differentiation. The three types of germ layers are the endoderm, ectoderm, and mesoderm." [https://github.com/obophenotype/uberon/issues/203, Wikipedia:Germ_layer] synonym: "germinal layer" EXACT [ncithesaurus:Germinal_Layer] xref: AAO:0000480 xref: BILA:0000035 xref: BTO:0000556 xref: EMAPA:36033 xref: FMA:69069 xref: GAID:1303 xref: MESH:D005855 xref: NCIT:C12950 xref: NCIT:C54105 xref: TAO:0001122 xref: UMLS:C0920502 {source="ncithesaurus:Embryonic_Tissue"} xref: UMLS:C1708239 {source="ncithesaurus:Germinal_Layer"} xref: VHOG:0001223 xref: Wikipedia:Germ_layer xref: XAO:0003011 xref: ZFA:0001122 is_a: UBERON:0010316 ! germ layer / neural crest relationship: RO:0002160 NCBITaxon:6072 ! only in taxon Eumetazoa [Term] id: UBERON:0000924 name: ectoderm namespace: uberon def: "Primary germ layer that is the outer of the embryo's three germ layers and gives rise to epidermis and neural tissue." [Wikipedia:Ectoderm] synonym: "embryonic ectoderm" EXACT [VHOG:0000153] xref: AAO:0000137 xref: BILA:0000036 xref: BTO:0000315 xref: CALOHA:TS-0216 xref: EFO:0000414 xref: EHDAA2:0000428 xref: EMAPA:16069 xref: EV:0100003 xref: FMA:69070 xref: GAID:1304 xref: MAT:0000155 xref: MAT:0000173 xref: MESH:D004475 xref: MIAA:0000173 xref: NCIT:C12703 xref: SCTID:362851007 xref: TAO:0000016 xref: UMLS:C0013574 {source="ncithesaurus:Ectoderm"} xref: VHOG:0000153 xref: Wikipedia:Ectoderm xref: XAO:0000001 xref: ZFA:0000016 is_a: UBERON:0000923 ! germ layer relationship: BFO:0000051 CL:0000221 ! has part ectodermal cell relationship: RO:0002495 UBERON:0006601 {source="Bgee:AN"} ! immediate transformation of presumptive ectoderm property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/1/19/Gray32.png" xsd:anyURI [Term] id: UBERON:0000925 name: endoderm namespace: uberon def: "Primary germ layer that lies remote from the surface of the embryo and gives rise to internal tissues such as gut." [Wikipedia:Endoderm] xref: AAO:0000139 xref: BILA:0000038 xref: BTO:0000800 xref: CALOHA:TS-0273 xref: EFO:0002545 xref: EHDAA2:0000436 xref: EMAPA:16062 xref: EV:0100005 xref: FMA:69071 xref: GAID:1305 xref: MAT:0000175 xref: MESH:D004707 xref: MIAA:0000175 xref: NCIT:C12706 xref: SCTID:362855003 xref: TAO:0000017 xref: UMLS:C0014144 {source="ncithesaurus:Endoderm"} xref: VHOG:0000154 xref: Wikipedia:Endoderm xref: XAO:0000090 xref: ZFA:0000017 is_a: UBERON:0000923 ! germ layer relationship: BFO:0000051 CL:0000223 ! has part endodermal cell relationship: RO:0002495 UBERON:0006595 {source="Bgee:AN"} ! immediate transformation of presumptive endoderm property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/c/c0/Endoderm2.png" xsd:anyURI property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/d/df/Gray10.png" xsd:anyURI [Term] id: UBERON:0000926 name: mesoderm namespace: uberon def: "The middle germ layer of the embryo, between the endoderm and ectoderm." [Wikipedia:Mesoderm] xref: AAO:0000304 xref: BILA:0000037 xref: BTO:0000839 xref: CALOHA:TS-0623 xref: EFO:0001981 xref: EHDAA2:0001128 xref: EHDAA:124 xref: EHDAA:160 xref: EHDAA:183 xref: EMAPA:16083 xref: EV:0100006 xref: FMA:69072 xref: GAID:522 xref: MAT:0000174 xref: MESH:D008648 xref: MIAA:0000174 xref: NCIT:C12750 xref: SCTID:362854004 xref: TAO:0000041 xref: UMLS:C0025485 {source="ncithesaurus:Mesoderm"} xref: VHOG:0000152 xref: Wikipedia:Mesoderm xref: XAO:0000050 xref: ZFA:0000041 is_a: UBERON:0000923 ! germ layer relationship: BFO:0000051 CL:0000222 ! has part mesodermal cell relationship: RO:0002495 UBERON:0006603 {source="Bgee:AN"} ! immediate transformation of presumptive mesoderm property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/e/e8/Mesoderm.png" xsd:anyURI [Term] id: UBERON:0000930 name: stomodeum namespace: uberon def: "Anterior part of the embryonic digestive tract that develops into a mouth. The stomodeum includes as parts an invagination of the ectoderm and the stomodeal cavity." [http://orcid.org/0000-0002-6601-2165, https://github.com/obophenotype/uberon/issues/326, Wikipedia:Stomodeum] synonym: "mouth primordium" EXACT [XAO:0000269] synonym: "primitive oral cavity" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "stomatodeum" EXACT [Wikipedia:Stomodeum] synonym: "stomodaeum" EXACT [] xref: BTO:0004224 xref: EHDAA2:0001929 xref: EMAPA:16263 xref: FMA:295846 xref: NCIT:C34306 xref: TAO:0001290 xref: TGMA:0000135 xref: UMLS:C1514977 {source="ncithesaurus:Stomodeum"} xref: Wikipedia:Stomodeum xref: XAO:0000269 xref: ZFA:0001290 is_a: UBERON:0013522 ! subdivision of tube relationship: BFO:0000050 UBERON:0000924 ! part of ectoderm relationship: BFO:0000050 UBERON:0035804 ! part of future mouth relationship: RO:0002160 NCBITaxon:6072 ! only in taxon Eumetazoa property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/9/93/Gray977.png" xsd:anyURI [Term] id: UBERON:0000931 name: proctodeum namespace: uberon def: "Inward fold on the surface of the embryonic ectoderm that develops into an ectodermal terminal part of the digestive tract." [https://github.com/obophenotype/uberon/issues/685, https://sourceforge.net/p/fbbtdv/tickets/52, ZFA:0000066] synonym: "embryonic proctodaeum" EXACT [] synonym: "proctodaeum" EXACT [] xref: AAO:0011087 xref: EHDAA2:0000121 xref: EMAPA:25038 xref: NCIT:C34278 xref: TAO:0000066 xref: UMLS:C0231054 {source="ncithesaurus:Proctodeum"} xref: VHOG:0000139 xref: Wikipedia:Proctodeum xref: XAO:0001019 xref: ZFA:0000066 is_a: UBERON:0016566 {source="EHDAA2"} ! pit relationship: BFO:0000050 UBERON:0007026 ! part of presumptive gut relationship: RO:0001025 UBERON:0012469 {source="EHDAA2"} ! located in external anal region relationship: RO:0002160 NCBITaxon:6072 ! only in taxon Eumetazoa relationship: RO:0002202 UBERON:0000924 ! develops from ectoderm relationship: RO:0002387 UBERON:0001353 ! has potential to develop into anal region property_value: x_1.1:contributor https://github.com/ANiknejad property_value: x_1.1:contributor https://github.com/cmungall property_value: x_1.1:contributor https://github.com/dosumis property_value: x_1.1:contributor https://github.com/mmc46 [Term] id: UBERON:0000945 name: stomach namespace: uberon def: "An expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ. A stomach is lined, in whole or in part by a glandular epithelium." [https://orcid.org/0000-0002-6601-2165, ISBN:0073040584, Wikipedia:Stomach] xref: AAO:0000579 xref: ANISEED:1235297 xref: BTO:0001307 xref: CALOHA:TS-0980 xref: EFO:0000837 xref: EHDAA2:0001915 xref: EHDAA:2993 xref: EMAPA:17021 xref: EV:0100070 xref: FMA:7148 xref: GAID:293 xref: galen:Stomach xref: MA:0000353 xref: MAT:0000051 xref: MESH:D013270 xref: MIAA:0000051 xref: NCIT:C12391 xref: SCTID:181246003 xref: TAO:0002121 xref: UMLS:C0038351 {source="ncithesaurus:Stomach"} xref: VHOG:0000408 xref: Wikipedia:Stomach xref: XAO:0000128 is_a: UBERON:0004921 {source="cjm"} ! subdivision of digestive tract is_a: UBERON:0010039 {source="cjm"} ! food storage organ relationship: BFO:0000050 UBERON:0001041 ! part of foregut relationship: RO:0002160 NCBITaxon:7776 ! only in taxon Gnathostomata relationship: RO:0002215 GO:0001696 ! capable of gastric acid secretion relationship: RO:0002433 UBERON:0001007 ! contributes to morphology of digestive system property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/e/e0/Stomach_diagram.svg" xsd:anyURI [Term] id: UBERON:0000947 name: aorta namespace: uberon def: "The main trunk of the systemic arterial system that carries blood from the heart to all the organs and other structures of the body, bringing oxygenated blood to all parts of the body in the systemic circulation." [http://orcid.org/0000-0002-6601-2165, ISBN:0-683-40008-8, MESH:A07.231.114.056, MP:0000272, Wikipedia:Aorta] synonym: "trunk of aortic tree" EXACT [] synonym: "trunk of systemic arterial tree" EXACT [] xref: AAO:0010213 xref: BTO:0000135 xref: CALOHA:TS-0046 xref: EFO:0000265 xref: EMAPA:18601 xref: EV:0100027 xref: FMA:3734 xref: GAID:469 xref: galen:Aorta xref: MA:0000062 xref: MAT:0000035 xref: MESH:D001011 xref: MIAA:0000035 xref: NCIT:C12669 xref: SCTID:181298001 xref: UMLS:C0003483 {source="ncithesaurus:Aorta"} xref: VHOG:0001523 xref: Wikipedia:Aorta xref: XAO:0003010 is_a: UBERON:0003509 {source="MA"} ! arterial blood vessel is_a: UBERON:0003519 ! thoracic cavity blood vessel is_a: UBERON:0013768 ! great vessel of heart relationship: BFO:0000050 RO:0002577 ! part of system relationship: BFO:0000050 UBERON:0010191 {source="EHDAA2"} ! part of aortic system relationship: RO:0002170 UBERON:0002084 ! connected to heart left ventricle property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/9/91/Aorta_scheme.jpg" xsd:anyURI [Term] id: UBERON:0000948 name: heart namespace: uberon def: "A myogenic muscular circulatory organ found in the vertebrate cardiovascular system composed of chambers of cardiac muscle. It is the primary circulatory organ." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Heart] synonym: "chambered heart" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "vertebrate heart" EXACT [] xref: AAO:0010210 xref: BILA:0000020 xref: BTO:0000562 xref: CALOHA:TS-0445 xref: EFO:0000815 xref: EHDAA2:0000738 xref: EHDAA:420 xref: EMAPA:16105 xref: EV:0100018 xref: FMA:7088 xref: GAID:174 xref: galen:Heart xref: MA:0000072 xref: MAT:0000036 xref: MESH:D006321 xref: MIAA:0000036 xref: NCIT:C12727 xref: SCTID:302509004 xref: TAO:0000114 xref: UMLS:C0018787 {source="ncithesaurus:Heart"} xref: VHOG:0000276 xref: Wikipedia:Heart xref: XAO:0000064 xref: ZFA:0000114 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005181 ! thoracic segment organ is_a: UBERON:0007100 ! primary circulatory organ is_a: UBERON:0010314 ! structure with developmental contribution from neural crest intersection_of: UBERON:0007100 ! primary circulatory organ intersection_of: BFO:0000051 UBERON:0004151 ! has part cardiac chamber relationship: BFO:0000050 UBERON:0015410 {source="MA"} ! part of heart plus pericardium relationship: BFO:0000051 UBERON:0004151 ! has part cardiac chamber relationship: RO:0002160 NCBITaxon:7742 ! only in taxon Vertebrata relationship: RO:0002202 UBERON:0004141 ! develops from heart tube relationship: RO:0002433 UBERON:0004535 ! contributes to morphology of cardiovascular system property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.0/VH_F_Heart.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Heart.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Heart.glb" xsd:anyURI [Term] id: UBERON:0000949 name: endocrine system namespace: uberon def: "Anatomical system that consists of the glands and parts of glands that produce endocrine secretions and help to integrate and control bodily metabolic activity." [NLM:endocrine+system, Wikipedia:Endocrine_system] synonym: "endocrine glandular system" EXACT [EHDAA2:0002224] synonym: "endocrine system" EXACT [] synonym: "systema endocrinum" EXACT [] xref: AAO:0010279 xref: CALOHA:TS-1301 xref: EFO:0002969 xref: EHDAA2:0002224 xref: EMAPA:35306 xref: EV:0100128 xref: FMA:9668 xref: GAID:439 xref: MA:0000012 xref: MESH:D004703 xref: NCIT:C12705 xref: SCTID:278876000 xref: TAO:0001158 xref: UMLS:C0014136 {source="ncithesaurus:Endocrine_System"} xref: VHOG:0000098 xref: Wikipedia:Endocrine_system xref: XAO:0000158 xref: ZFA:0001158 is_a: UBERON:0015204 ! glandular system disjoint_from: UBERON:0000990 ! reproductive system disjoint_from: UBERON:0001004 ! respiratory system disjoint_from: UBERON:0001007 ! digestive system disjoint_from: UBERON:0001009 ! circulatory system disjoint_from: UBERON:0001016 ! nervous system disjoint_from: UBERON:0001434 ! skeletal system disjoint_from: UBERON:0002204 ! musculoskeletal system disjoint_from: UBERON:0002294 ! biliary system disjoint_from: UBERON:0002330 ! exocrine system disjoint_from: UBERON:0002390 ! hematopoietic system disjoint_from: UBERON:0002405 ! immune system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:8450002 ! excretory system relationship: RO:0002160 NCBITaxon:6072 ! only in taxon Eumetazoa relationship: RO:0002473 UBERON:0002368 ! composed primarily of endocrine gland relationship: RO:0002492 UBERON:0000066 ! existence ends during fully formed stage [Term] id: UBERON:0000955 name: brain namespace: uberon def: "The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals. Some primitive animals such as jellyfish and starfish have a decentralized nervous system without a brain, while sponges lack any nervous system at all. In vertebrates, the brain is located in the head, protected by the skull and close to the primary sensory apparatus of vision, hearing, balance, taste, and smell[WP]." [https://github.com/obophenotype/uberon/issues/300, Wikipedia:Brain] xref: AAO:0010478 xref: ABA:Brain xref: BAMS:Br xref: BAMS:Brain xref: BILA:0000135 xref: BIRNLEX:796 xref: BTO:0000142 xref: CALOHA:TS-0095 xref: DHBA:10155 xref: EFO:0000302 xref: EHDAA2:0000183 xref: EHDAA:2641 xref: EHDAA:6485 xref: EMAPA:16894 xref: EV:0100164 xref: FMA:50801 xref: GAID:571 xref: galen:Brain xref: HBA:4005 xref: MA:0000168 xref: MAT:0000098 xref: MBA:8 xref: MBA:997 xref: MESH:D001921 xref: MIAA:0000098 xref: NCIT:C12439 xref: neuronames:21 {source="BIRNLEX:796"} xref: PBA:3999 xref: SCTID:258335003 xref: TAO:0000008 xref: UMLS:C0006104 {source="ncithesaurus:Brain", source="BIRNLEX:796"} xref: UMLS:C1269537 {source="BIRNLEX:796"} xref: VHOG:0000157 xref: Wikipedia:Brain xref: XAO:0000010 xref: ZFA:0000008 is_a: UBERON:0000062 {source="GO"} ! organ is_a: UBERON:0004121 ! ectoderm-derived structure relationship: BFO:0000050 UBERON:0001017 {source="FMA"} ! part of central nervous system relationship: BSPO:0000123 UBERON:0000468 ! in anterior side of multicellular organism relationship: RO:0002202 UBERON:0001049 {gci_filler="NCBITaxon:7711", gci_relation="BFO:0000050"} ! develops from neural tube relationship: RO:0002215 GO:0050890 {gci_filler="NCBITaxon:9606", gci_relation="BFO:0000050"} ! capable of cognition relationship: RO:0002433 UBERON:0001016 ! contributes to morphology of nervous system relationship: RO:0002473 CL:0002319 ! composed primarily of neural cell relationship: RO:0002492 UBERON:0000066 ! existence ends during fully formed stage relationship: RO:0002495 UBERON:0006238 {source="Bgee:AN"} ! immediate transformation of future brain property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/Allen_F_Brain.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/Allen_M_Brain.glb" xsd:anyURI property_value: x_1.1:contributor https://github.com/cmungall [Term] id: UBERON:0000957 name: lamina namespace: uberon def: "Any thin layer or plate." [Wikipedia:Lamina_of_the_vertebral_arch] synonym: "laminar tissue" EXACT [] xref: Wikipedia:Lamina_of_the_vertebral_arch is_a: UBERON:0000479 ! tissue intersection_of: UBERON:0000479 ! tissue intersection_of: RO:0000086 PATO:0002124 ! has quality laminar relationship: RO:0000086 PATO:0002124 ! has quality laminar property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/8/80/Laminaarcusvertebrae.png" xsd:anyURI [Term] id: UBERON:0000962 name: nerve of cervical vertebra namespace: uberon def: "The cervical nerves are the spinal nerves from the cervical vertebrae. Although there are seven cervical vertebrae (C1-C7), there are eight cervical nerves (C1-C8). All nerves except C8 emerge above their corresponding vertebrae, while the C8 nerve emerges below the C7 vertebra. (In the other portions of the spine, the nerve emerges below the vertebra with the same name. Dorsal (posterior) distribution includes the greater occipital (C2) and third occipital (C3). Ventral (anterior) distribution includes the cervical plexus (C1-C4) and brachial plexus (C5-C8) [WP,unvetted]." [Wikipedia:Cervical_nerves] synonym: "cervical nerve" EXACT [FMA:5859] synonym: "cervical nerve tree" EXACT [] synonym: "cervical spinal nerve" EXACT [] xref: BAMS:cern xref: FMA:5859 xref: NCIT:C32299 xref: neuronames:2351 xref: NLXANAT:20090207 xref: SCTID:360497008 xref: UMLS:C0228815 {source="ncithesaurus:Cervical_Nerve"} xref: Wikipedia:Cervical_nerves is_a: UBERON:0001780 ! spinal nerve intersection_of: UBERON:0001780 ! spinal nerve intersection_of: extends_fibers_into UBERON:0002726 ! cervical spinal cord relationship: extends_fibers_into UBERON:0002726 ! cervical spinal cord property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/e/e6/Gray795.png" xsd:anyURI [Term] id: UBERON:0000963 name: head sensillum namespace: uberon xref: MAT:0000204 xref: MIAA:0000204 is_a: UBERON:0002536 ! arthropod sensillum intersection_of: UBERON:0002536 ! arthropod sensillum intersection_of: BFO:0000050 UBERON:0000033 ! part of head relationship: BFO:0000050 UBERON:0000033 ! part of head [Term] id: UBERON:0000964 name: cornea namespace: uberon def: "The transparent anterior portion of the fibrous coat of the eye that serves as the chief refractory structure." [ISBN:0-683-40008-8, MESH:A09.371.060.217, MP:0001312] synonym: "cornea of camera-type eye" EXACT [GO:0061303] xref: AAO:0010344 xref: BTO:0000286 xref: CALOHA:TS-0171 xref: EFO:0000377 xref: EHDAA2:0000316 xref: EHDAA:10199 xref: EMAPA:17161 xref: EV:0100341 xref: FMA:58238 xref: GAID:892 xref: MA:0000266 xref: MESH:D003315 xref: NCIT:C12342 xref: SCTID:181162001 xref: TAO:0000640 xref: UMLS:C0010031 {source="ncithesaurus:Cornea"} xref: VHOG:0000164 xref: Wikipedia:Cornea xref: XAO:0000180 xref: ZFA:0000640 is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0010000 ! multicellular anatomical structure is_a: UBERON:0010313 ! neural crest-derived structure relationship: BFO:0000050 UBERON:0001801 {source="MA"} ! part of anterior segment of eyeball relationship: BFO:0000050 UBERON:0010409 {source="MA"} ! part of ocular surface region relationship: BFO:0000050 UBERON:0012430 {source="FMA-isa"} ! part of tunica fibrosa of eyeball relationship: BFO:0000051 UBERON:0001772 ! has part corneal epithelium relationship: BFO:0000051 UBERON:0004370 ! has part anterior limiting lamina of cornea relationship: RO:0000086 PATO:0000964 ! has quality transparent relationship: RO:0002150 UBERON:0001773 ! continuous with sclera relationship: RO:0002202 UBERON:0004348 ! develops from optic eminence relationship: RO:0002202 UBERON:0005427 ! develops from corneal primordium relationship: RO:0002256 UBERON:0005426 ! developmentally induced by lens vesicle relationship: RO:0002433 UBERON:0001801 ! contributes to morphology of anterior segment of eyeball property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg" xsd:anyURI [Term] id: UBERON:0000965 name: lens of camera-type eye namespace: uberon def: "A transparent and refractive lens located posterior to the iris. The lens of camera-type eye refracts light to be focused on the retina." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Lens_(anatomy)] synonym: "camera-type eye lens" EXACT [GO:0002088] synonym: "lens crystallina" EXACT [Wikipedia:Lens_(anatomy)] xref: AAO:0010348 xref: BTO:0000723 xref: CALOHA:TS-0545 xref: EHDAA:9057 xref: EMAPA:17838 xref: EV:0100343 xref: FMA:58241 xref: MA:0000275 xref: MAT:0000141 xref: MESH:D007908 xref: MIAA:0000141 xref: NCIT:C12743 xref: RETIRED_EHDAA2:0000975 xref: SCTID:181169005 xref: TAO:0000035 xref: UMLS:C0023317 {source="ncithesaurus:Crystalline_Lens"} xref: VHOG:0000169 xref: Wikipedia:Lens_(anatomy) xref: XAO:0000008 xref: ZFA:0000035 is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0005389 ! transparent eye structure relationship: BFO:0000050 UBERON:0001801 ! part of anterior segment of eyeball relationship: RO:0002202 UBERON:0005426 ! develops from lens vesicle relationship: RO:0002256 UBERON:0003902 ! developmentally induced by retinal neural layer relationship: RO:0002433 UBERON:0001801 ! contributes to morphology of anterior segment of eyeball [Term] id: UBERON:0000966 name: retina namespace: uberon def: "The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates." [Wikipedia:Retina, ZFIN:curator] synonym: "inner layer of eyeball" EXACT [] synonym: "retina of camera-type eye" EXACT [GO:0060041] synonym: "tunica interna of eyeball" EXACT [] xref: AAO:0010352 xref: BAMS:R xref: BIRNLEX:1153 xref: BTO:0001175 xref: CALOHA:TS-0865 xref: EFO:0000832 xref: EHDAA2:0001627 xref: EHDAA:4757 xref: EMAPA:17168 xref: EV:0100348 xref: FMA:58301 xref: GAID:755 xref: MA:0000276 xref: MAT:0000142 xref: MBA:304325711 xref: MESH:D012160 xref: MIAA:0000142 xref: NCIT:C12343 xref: neuronames:1862 xref: NIFSTD_RETIRED:birnlex_1156 xref: SCTID:181171005 xref: TAO:0000152 xref: UMLS:C0035298 {source="BIRNLEX:1153", source="ncithesaurus:Retina"} xref: UMLS:C1278894 {source="BIRNLEX:1153"} xref: VHOG:0000229 xref: Wikipedia:Retina xref: XAO:0000009 xref: ZFA:0000152 is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0005388 ! photoreceptor array relationship: BFO:0000050 UBERON:0001802 ! part of posterior segment of eyeball relationship: BFO:0000050 UBERON:0019207 ! part of chorioretinal region relationship: BFO:0000051 CL:0000573 {source="FMA"} ! has part retinal cone cell relationship: BFO:0000051 CL:0000604 {source="FMA"} ! has part retinal rod cell relationship: BFO:0000051 CL:0000740 {source="FMA"} ! has part retinal ganglion cell relationship: RO:0002202 UBERON:0003072 {source="EHDAA2"} ! develops from optic cup property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/e/ed/Human_eye_cross-sectional_view_grayscale.png" xsd:anyURI [Term] id: UBERON:0000970 name: eye namespace: uberon def: "An organ that detects light." [https://orcid.org/0000-0002-6601-2165] xref: BILA:0000017 xref: BTO:0000439 xref: CALOHA:TS-0309 xref: EFO:0000827 xref: EV:0100336 xref: GAID:69 xref: MAT:0000140 xref: MESH:D005123 xref: MIAA:0000140 xref: Wikipedia:Eye is_a: UBERON:0000020 ! sense organ relationship: BFO:0000050 UBERON:0002104 ! part of visual system relationship: BFO:0000051 CL:0000149 {source="PMID:21062451"} ! has part visual pigment cell relationship: BFO:0000051 CL:0000210 {source="PMID:21062451"} ! has part photoreceptor cell relationship: RO:0002215 GO:0009584 ! capable of detection of visible light property_value: IAO:0000232 "This class encompasses a variety of light-detecting structures from different phyla with no implication of homology, from the compound insect eye to the vertebrate camera-type eye (distinct classes are provided for each)" xsd:string [Term] id: UBERON:0000971 name: ommatidium namespace: uberon def: "The smallest morphological and functional unit of the compound eye that consists of a usually limited and often constant number of rhabdomeric photoreceptor cells, cornea-secreting epithelial cells, and interommatidial pigment cells, and may additionally contain crystalline cone cells." [PMID:21062451] synonym: "omatidium" EXACT [] xref: BTO:0001922 xref: HAO:0000666 xref: MAT:0000143 xref: MIAA:0000143 xref: Wikipedia:Ommatidium is_a: UBERON:0000970 {source="PMID:21062451"} ! eye is_a: UBERON:0002536 ! arthropod sensillum relationship: BFO:0000050 UBERON:0000018 ! part of compound eye [Term] id: UBERON:0000974 name: neck namespace: uberon def: "An organism subdivision that extends from the head to the pectoral girdle, encompassing the cervical vertebral column." [http://orcid.org/0000-0002-6601-2165] xref: AEO:0000108 xref: BTO:0000420 xref: CALOHA:TS-2045 xref: EFO:0000967 xref: EHDAA2:0003108 xref: EMAPA:35587 xref: FMA:7155 xref: GAID:86 xref: galen:Neck xref: MA:0000024 xref: MAT:0000297 xref: MESH:D009333 xref: MIAA:0000297 xref: NCIT:C13063 xref: SCTID:302550007 xref: UMLS:C0027530 {source="ncithesaurus:Neck"} xref: Wikipedia:Neck is_a: UBERON:0000475 ! organism subdivision relationship: anteriorly_connected_to UBERON:0000033 ! head relationship: BFO:0000050 RO:0002577 ! part of system relationship: BFO:0000050 UBERON:0000153 ! part of anterior region of body relationship: posteriorly_connected_to UBERON:0002100 ! trunk property_value: IAO:0000232 "true necks are considered to be present when the pectoral girdle is separate from the skull - Tiktaalik is the earliest known fish to have a true neck." xsd:string property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/9/99/Female_neck.jpg" xsd:anyURI [Term] id: UBERON:0000977 name: pleura namespace: uberon def: "The invaginated serous membrane that surrounds the lungs (the visceral portion) and lines the walls of the pleural cavity (parietal portion)." [https://github.com/obophenotype/uberon/issues/1231, ISBN:0-683-40008-8, MP:0010820, UBERON:cjm, Wikipedia:Pulmonary_pleurae] synonym: "wall of pleural sac" EXACT [] xref: BTO:0001791 xref: CALOHA:TS-2081 xref: EFO:0001980 xref: EMAPA:16775 xref: EV:0100044 xref: FMA:9583 xref: GAID:360 xref: MA:0000433 xref: MESH:D010994 xref: NCIT:C12469 xref: SCTID:181609007 xref: UMLS:C0032225 {source="ncithesaurus:Pleural_Tissue"} xref: VHOG:0000394 xref: Wikipedia:Pleura is_a: UBERON:0000042 ! serous membrane is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure intersection_of: UBERON:0000042 ! serous membrane intersection_of: BFO:0000050 UBERON:0009778 ! part of pleural sac intersection_of: BFO:0000051 UBERON:0002400 ! has part parietal pleura intersection_of: BFO:0000051 UBERON:0002401 ! has part visceral pleura relationship: BFO:0000050 UBERON:0009778 {source="https://github.com/obophenotype/uberon/issues/86"} ! part of pleural sac relationship: BFO:0000051 UBERON:0002400 ! has part parietal pleura relationship: BFO:0000051 UBERON:0002401 ! has part visceral pleura relationship: RO:0000086 PATO:0001748 ! has quality invaginated relationship: RO:0002160 NCBITaxon:32524 ! only in taxon Amniota relationship: RO:0002202 UBERON:0003081 ! develops from lateral plate mesoderm relationship: RO:0002433 UBERON:0001004 ! contributes to morphology of respiratory system property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/a/ab/Gray965.png" xsd:anyURI [Term] id: UBERON:0000982 name: skeletal joint namespace: uberon def: "Anatomical structure that consists of two or more adjacent skeletal structures, which may be interconnected by various types of tissue[VSAO]." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, VSAO:0000101, Wikipedia:Joint] xref: AEO:0000182 xref: BTO:0001686 xref: CALOHA:TS-2023 xref: EFO:0000948 xref: EMAPA:35456 xref: FMA:7490 xref: GAID:102 xref: galen:Joint xref: MA:0000319 xref: MAT:0000188 xref: MESH:D007596 xref: MIAA:0000188 xref: NCIT:C13044 xref: RETIRED_EHDAA2:0003182 xref: SCTID:302536002 xref: TAO:0000367 xref: UMLS:C0022417 {source="ncithesaurus:Joint"} xref: VHOG:0001276 xref: VSAO:0000101 xref: Wikipedia:Joint xref: XAO:0000171 xref: ZFA:0001596 is_a: UBERON:0004905 ! articulation union_of: UBERON:0002217 ! synovial joint union_of: UBERON:0011134 ! nonsynovial joint disjoint_from: UBERON:0001474 ! bone element relationship: RO:0002176 UBERON:0004765 ! connects skeletal element relationship: RO:0002433 UBERON:0001434 ! contributes to morphology of skeletal system [Term] id: UBERON:0000988 name: pons namespace: uberon def: "The part of the central nervous system lying between the medulla oblongata and the midbrain, ventral to the cerebellum." [VHOG:0001176] synonym: "pons of Varolius" EXACT [] synonym: "pons Varolii" EXACT [ncithesaurus:Pons_Varolii] xref: BAMS:PONS xref: BAMS:Pons xref: BIRNLEX:733 xref: BM:Pons xref: BTO:0001101 xref: CALOHA:TS-0813 xref: DHBA:10661 xref: EFO:0001394 xref: EHDAA2:0004394 xref: EMAPA:17563 xref: EV:0100253 xref: FMA:67943 xref: GAID:578 xref: HBA:9131 xref: MA:0000204 xref: MAT:0000115 xref: MBA:771 xref: MESH:D011149 xref: MIAA:0000115 xref: NCIT:C12511 xref: neuronames:547 {source="BIRNLEX:733"} xref: SCTID:279103004 xref: UMLS:C0032639 {source="BIRNLEX:733", source="ncithesaurus:Pons_Varolii"} xref: UMLS:C1280999 {source="BIRNLEX:733"} xref: VHOG:0001176 xref: Wikipedia:Pons is_a: UBERON:0002616 ! regional part of brain relationship: BFO:0000050 UBERON:0001895 {source="neuronames"} ! part of metencephalon relationship: BFO:0000050 UBERON:0002298 ! part of brainstem relationship: RO:0002160 NCBITaxon:7742 ! only in taxon Vertebrata relationship: RO:0002433 UBERON:0001895 ! contributes to morphology of metencephalon relationship: RO:0002433 UBERON:0002298 ! contributes to morphology of brainstem property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/3/36/Gray768.png" xsd:anyURI [Term] id: UBERON:0000989 name: penis namespace: uberon def: "An intromittent organ in certain biologically male organisms. In placental mammals, this also serves as the organ of urination." [http://orcid.org/0000-0002-6601-2165, ISBN:0-683-40008-8, MP:0005187, Wikipedia:Penis] xref: BTO:0000405 xref: CALOHA:TS-0758 xref: EFO:0000987 xref: EHDAA2:0001433 xref: EHDAA:9380 xref: EMAPA:18682 xref: EMAPA_RETIRED:18996 xref: EV:0100107 xref: FMA:9707 xref: GAID:389 xref: galen:Penis xref: MA:0000408 xref: MAT:0000186 xref: MESH:D010413 xref: MIAA:0000186 xref: NCIT:C12409 xref: SCTID:265793009 xref: UMLS:C0030851 {source="ncithesaurus:Penis"} xref: VHOG:0000727 xref: Wikipedia:Penis is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0008811 {source="Wikipedia"} ! intromittent organ relationship: RO:0002202 UBERON:0004876 {source="Wikipedia"} ! develops from urogenital fold relationship: RO:0002202 UBERON:0005876 {source="EHDAA2"} ! develops from undifferentiated genital tubercle property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/8/87/Labelled_flaccid_penis.jpg" xsd:anyURI [Term] id: UBERON:0000990 name: reproductive system namespace: uberon def: "Anatomical system that has as its parts the organs concerned with reproduction." [Wikipedia:Reproductive_system] xref: AAO:0010258 xref: BILA:0000103 xref: BTO:0000081 xref: CALOHA:TS-1318 xref: EFO:0000809 xref: EHDAA2:0001603 xref: EHDAA:5923 xref: EMAPA:17381 xref: EV:0100100 xref: FMA:7160 xref: GAID:363 xref: HAO:0000374 xref: HAO:0000895 xref: MA:0000326 xref: MIAA:0000305 xref: NCIT:C12841 xref: SCTID:278875001 xref: TAO:0000632 xref: UMLS:C1261210 {source="ncithesaurus:Reproductive_System"} xref: VHOG:0000182 xref: WBbt:0005747 xref: Wikipedia:Reproductive_system xref: XAO:0000142 xref: ZFA:0000632 is_a: UBERON:0000467 ! anatomical system intersection_of: UBERON:0000467 ! anatomical system intersection_of: RO:0002216 GO:0000003 ! capable of part of reproduction disjoint_from: UBERON:0001004 ! respiratory system disjoint_from: UBERON:0001007 ! digestive system disjoint_from: UBERON:0001009 ! circulatory system disjoint_from: UBERON:0001016 ! nervous system disjoint_from: UBERON:0001434 ! skeletal system disjoint_from: UBERON:0002204 ! musculoskeletal system disjoint_from: UBERON:0002294 ! biliary system disjoint_from: UBERON:0002330 ! exocrine system disjoint_from: UBERON:0002390 ! hematopoietic system disjoint_from: UBERON:0002405 ! immune system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:8450002 ! excretory system relationship: BFO:0000051 UBERON:0000991 ! has part gonad relationship: RO:0002216 GO:0000003 ! capable of part of reproduction relationship: RO:0002492 UBERON:0000066 ! existence ends during fully formed stage property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/5/52/Penis.svg" xsd:anyURI [Term] id: UBERON:0000991 name: gonad namespace: uberon def: "Reproductive organ that produces and releases eggs (ovary) or sperm (testis)." [ISBN:0140512888, Wikipedia:Gonad, ZFA:0000413, ZFIN:curator] synonym: "gonada" EXACT [] xref: AAO:0000213 xref: BILA:0000123 xref: BSA:0000079 xref: BTO:0000534 xref: EMAPA:17383 xref: FMA:18250 xref: GAID:368 xref: HAO:0000379 xref: MA:0002420 xref: MESH:D006066 xref: NCIT:C12725 xref: SCTID:304623008 xref: TAO:0000413 xref: UMLS:C0018067 {source="ncithesaurus:Gonad"} xref: VHOG:0000397 xref: WBbt:0005175 xref: Wikipedia:Gonad xref: XAO:0003146 xref: ZFA:0000413 is_a: UBERON:0003133 ! reproductive organ intersection_of: UBERON:0003133 ! reproductive organ intersection_of: BFO:0000051 CL:0000586 ! has part germ cell relationship: BFO:0000051 CL:0000586 ! has part germ cell relationship: BFO:0000067 GO:0007276 ! contains process gamete generation relationship: RO:0002202 UBERON:0005564 ! develops from gonad primordium [Term] id: UBERON:0000992 name: ovary namespace: uberon def: "The gonad of a female organism which contains germ cells." [ISBN:0-683-40008-8, MP:0001126, Wikipedia:Ovary] synonym: "animal ovary" EXACT [EFO:0000973] synonym: "female gonad" EXACT [] synonym: "female organism genitalia gonad" EXACT [OBOL:automatic] synonym: "female organism genitalia gonada" EXACT [OBOL:automatic] synonym: "female organism reproductive system gonad" EXACT [OBOL:automatic] synonym: "female organism reproductive system gonada" EXACT [OBOL:automatic] synonym: "female reproductive system gonad" EXACT [OBOL:automatic] synonym: "female reproductive system gonada" EXACT [OBOL:automatic] synonym: "genitalia of female organism gonad" EXACT [OBOL:automatic] synonym: "genitalia of female organism gonada" EXACT [OBOL:automatic] synonym: "gonad of female organism genitalia" EXACT [OBOL:automatic] synonym: "gonad of female organism reproductive system" EXACT [OBOL:automatic] synonym: "gonad of female reproductive system" EXACT [OBOL:automatic] synonym: "gonad of genitalia of female organism" EXACT [OBOL:automatic] synonym: "gonad of reproductive system of female organism" EXACT [OBOL:automatic] synonym: "gonada of female organism genitalia" EXACT [OBOL:automatic] synonym: "gonada of female organism reproductive system" EXACT [OBOL:automatic] synonym: "gonada of female reproductive system" EXACT [OBOL:automatic] synonym: "gonada of genitalia of female organism" EXACT [OBOL:automatic] synonym: "gonada of reproductive system of female organism" EXACT [OBOL:automatic] synonym: "reproductive system of female organism gonad" EXACT [OBOL:automatic] synonym: "reproductive system of female organism gonada" EXACT [OBOL:automatic] xref: AAO:0000371 xref: BILA:0000125 xref: BSA:0000080 xref: BTO:0000975 xref: CALOHA:TS-0730 xref: EFO:0000973 xref: EHDAA2:0001360 xref: EHDAA:8124 xref: EMAPA:17962 xref: EV:0100111 xref: FMA:7209 xref: GAID:367 xref: MA:0000384 xref: MESH:D010053 xref: MIAA:0000125 xref: NCIT:C12404 xref: SCTID:181464007 xref: TAO:0000403 xref: UMLS:C0029939 {source="ncithesaurus:Ovary"} xref: VHOG:0000251 xref: Wikipedia:Ovary xref: XAO:0000258 xref: ZFA:0000403 is_a: UBERON:0000991 ! gonad is_a: UBERON:0003134 ! female reproductive organ intersection_of: UBERON:0000991 ! gonad intersection_of: BFO:0000050 UBERON:0000474 ! part of female reproductive system disjoint_from: UBERON:0009117 ! indifferent gonad relationship: BSPO:0000126 UBERON:0003975 {gci_filler="NCBITaxon:40674", gci_relation="BFO:0000050", source="FMA-abduced-lr"} ! in lateral side of internal female genitalia relationship: RO:0002160 NCBITaxon:33208 ! only in taxon Metazoa relationship: RO:0002202 UBERON:0009117 ! develops from indifferent gonad property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/d/d4/Gray589.png" xsd:anyURI property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/c/cb/Female_anatomy.png" xsd:anyURI [Term] id: UBERON:0000993 name: oviduct namespace: uberon def: "A tube or collection of tubes in an animal from the ovaries to the outside of the body." [http://orcid.org/0000-0002-6601-2165] synonym: "ovarian duct" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "ovarian tube" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "uterine tube" EXACT [] xref: AAO:0010533 xref: BSA:0000083 xref: BTO:0000980 xref: EFO:0000974 xref: EMAPA:18984 xref: GAID:366 xref: MAT:0000126 xref: MESH:D010057 xref: MIAA:0000126 xref: NCIT:C77957 xref: TAO:0000560 xref: UMLS:C0029954 {source="ncithesaurus:Oviduct"} xref: VHOG:0001136 xref: Wikipedia:Oviduct xref: XAO:0003052 xref: ZFA:0000560 is_a: UBERON:0000025 ! tube is_a: UBERON:0005156 ! reproductive structure relationship: BFO:0000050 UBERON:0000474 ! part of female reproductive system relationship: RO:0002160 NCBITaxon:6072 ! only in taxon Eumetazoa relationship: RO:0002176 UBERON:0000992 ! connects ovary relationship: RO:0002176 UBERON:0013514 ! connects space surrounding organism property_value: IAO:0000232 "sometimes oviduct is used interchangeably with follaopian tube. Here they are different - the oviduct connects the gonad to the outside in a variety of animals. The mammal-class fallopian tube is derived from the mullerian duct and connects the gonads/infubdibulum to the uterus" xsd:string [Term] id: UBERON:0000995 name: uterus namespace: uberon def: "The female muscular organ of gestation in which the developing embryo or fetus is nourished until birth." [MGI:csmith, MP:0001120] xref: BTO:0001424 xref: CALOHA:TS-1102 xref: EFO:0000975 xref: EMAPA:29915 xref: EV:0100113 xref: FMA:17558 xref: GAID:172 xref: galen:Uterus xref: MA:0000389 xref: MAT:0000127 xref: MESH:D014599 xref: MIAA:0000127 xref: NCIT:C12405 xref: SCTID:181452004 xref: UMLS:C0042149 {source="ncithesaurus:Uterus"} xref: VHOG:0001137 xref: Wikipedia:Uterus is_a: UBERON:0013515 {source="cjm"} ! subdivision of oviduct relationship: BFO:0000050 UBERON:0004175 ! part of internal genitalia relationship: RO:0002160 NCBITaxon:32525 ! only in taxon Theria relationship: RO:0002495 UBERON:0005795 ! immediate transformation of embryonic uterus property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/6/6a/Female_reproductive_system_lateral_nolabel.png" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Uterus.glb" xsd:anyURI property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/c/cb/Female_anatomy.png" xsd:anyURI [Term] id: UBERON:0000997 name: mammalian vulva namespace: uberon def: "External genital organs of the female mammal[WP]." [Wikipedia:Vulva] synonym: "mammalian vulva" EXACT [] synonym: "puboperineal region" EXACT [FMA:20462] synonym: "vulva" EXACT [MA:0000395] xref: BTO:0003101 xref: CALOHA:TS-1168 xref: EFO:0000978 xref: EMAPA:36631 xref: EV:0100118 xref: FMA:20462 xref: GAID:383 xref: galen:Vulva xref: MA:0000395 xref: MAT:0000169 xref: MESH:D014844 xref: MIAA:0000169 xref: NCIT:C12408 xref: SCTID:265796001 xref: UMLS:C0042993 {source="ncithesaurus:Vulva"} xref: VHOG:0001458 xref: Wikipedia:Vulva is_a: UBERON:0000062 ! organ is_a: UBERON:0005156 ! reproductive structure relationship: BFO:0000050 UBERON:0005056 ! part of external female genitalia relationship: RO:0002160 NCBITaxon:40674 ! only in taxon Mammalia property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/d/da/Female_unshaved_genitalia.jpg" xsd:anyURI [Term] id: UBERON:0000998 name: seminal vesicle namespace: uberon def: "Either of a pair of glandular pouches that lie one on either side of the male reproductive tract posterolateral to the urinary bladder and in the human male secrete a sugar- and protein-containing fluid into the ejaculatory duct." [BTO:0001234, Wikipedia:Seminal_vesicle] xref: AAO:0010788 xref: BTO:0001234 xref: CALOHA:TS-0919 xref: EFO:0000986 xref: EMAPA:19180 xref: EV:0100106 xref: FMA:19386 xref: GAID:394 xref: MA:0000410 xref: MAT:0000171 xref: MESH:D012669 xref: MIAA:0000171 xref: NCIT:C12787 xref: SCTID:181434004 xref: UMLS:C0036628 {source="ncithesaurus:Seminal_Vesicle"} xref: VHOG:0001379 xref: Wikipedia:Seminal_vesicle is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0006868 ! seminal fluid secreting gland relationship: BFO:0000050 UBERON:0000473 ! part of testis relationship: RO:0002202 UBERON:0000080 ! develops from mesonephros relationship: RO:0002433 UBERON:0004054 ! contributes to morphology of internal male genitalia relationship: RO:0003000 UBERON:0010143 ! produces seminal vesicle fluid property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/d/d1/Male_anatomy_en.svg" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Prostate.glb" xsd:anyURI [Term] id: UBERON:0000999 name: ejaculatory duct namespace: uberon def: "The Ejaculatory ducts (ductus ejaculatorii) are paired structures in male anatomy, about 2 cm in length. Each ejaculatory duct is formed by the union of the vas deferens with the duct of the seminal vesicle. They pass through the prostate, and empty into the urethra at the Colliculus seminalis. During ejaculation, semen passes through the ducts and exits the body via the penis[WP,unvetted]." [Wikipedia:Ejaculatory_duct] synonym: "ductus ejaculatorius" EXACT [BTO:0001580] xref: BTO:0001580 xref: CALOHA:TS-0211 xref: EFO:0000985 xref: EMAPA:19088 xref: FMA:19325 xref: GAID:388 xref: MA:0003247 xref: MAT:0000170 xref: MESH:D004543 xref: MIAA:0000170 xref: NCIT:C32493 xref: SCTID:279665005 xref: UMLS:C0013747 {source="ncithesaurus:Ejaculatory_Duct"} xref: Wikipedia:Ejaculatory_duct is_a: UBERON:0000025 ! tube is_a: UBERON:0005904 ! duct of male reproductive system is_a: UBERON:0015212 ! lateral structure relationship: BSPO:0000126 UBERON:0000079 ! in lateral side of male reproductive system relationship: channel_for UBERON:0001968 ! semen relationship: channel_for UBERON:0010143 ! seminal vesicle fluid relationship: channels_from UBERON:0000998 ! seminal vesicle relationship: channels_from UBERON:0001000 ! vas deferens relationship: channels_into UBERON:0000057 ! urethra relationship: RO:0002160 NCBITaxon:7742 ! only in taxon Vertebrata relationship: RO:0002216 GO:0042713 ! capable of part of sperm ejaculation property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Prostate.glb" xsd:anyURI property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/3/35/Male_anatomy.png" xsd:anyURI [Term] id: UBERON:0001000 name: vas deferens namespace: uberon def: "A secretory duct that transports sperm from the testis. In mammals this is a continuation of the epididymis and ends in the prostatic urethra where it terminates to form ejaculatory duct." [http://orcid.org/0000-0002-6601-2165, ISBN:0-683-40008-8, MGI:pvb, MP:0002769, Wikipedia:Vas_deferens] synonym: "deferent duct" EXACT [] synonym: "ductus deferens" EXACT [Wikipedia:Vas_deferens] synonym: "vas deferen" EXACT [] xref: BTO:0001427 xref: CALOHA:TS-1105 xref: EFO:0000981 xref: EMAPA:18681 xref: EV:0100105 xref: FMA:19234 xref: GAID:404 xref: galen:VasDeferens xref: MA:0000413 xref: MESH:D014649 xref: MIAA:0000129 xref: NCIT:C12813 xref: SCTID:245467009 xref: UMLS:C0042360 {source="ncithesaurus:Vas_Deferens"} xref: VHOG:0001135 xref: Wikipedia:Vas_deferens is_a: UBERON:0000025 ! tube is_a: UBERON:0005904 ! duct of male reproductive system relationship: BFO:0000050 UBERON:0005352 {source="FMA"} ! part of spermatic cord relationship: BFO:0000050 UBERON:0006947 ! part of male genital duct relationship: channel_for UBERON:0001968 ! semen relationship: channels_from UBERON:0001301 ! epididymis relationship: channels_into UBERON:0000999 ! ejaculatory duct relationship: RO:0002160 NCBITaxon:32524 ! only in taxon Amniota relationship: RO:0002433 UBERON:0004054 ! contributes to morphology of internal male genitalia property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/d/d1/Male_anatomy_en.svg" xsd:anyURI [Term] id: UBERON:0001001 name: chitin-based cuticle namespace: uberon def: "A cuticular covering that is composed primarily of chitin. The main structural component of arthropod cuticle is a polysaccharide, chitin, composed of N-acetylglucosamine units, together with proteins and lipids[WP]." [https://orcid.org/0000-0002-6601-2165, https://sourceforge.net/tracker/index.php?func=detail&aid=3348965&group_id=36855&atid=440764, Wikipedia:Arthropod_exoskeleton, Wikipedia:Cuticle#Invertebrate_zoology] xref: EFO:0000944 xref: HAO:0000240 xref: MAT:0000150 xref: MIAA:0000150 xref: Wikipedia:Arthropod_exoskeleton is_a: UBERON:0001002 ! cuticle is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0007491 ! chitin-based acellular structure intersection_of: UBERON:0001002 ! cuticle intersection_of: RO:0002473 CHEBI:17029 ! composed primarily of chitin relationship: BFO:0000050 UBERON:0002416 ! part of integumental system relationship: RO:0002160 NCBITaxon:6656 ! only in taxon Arthropoda relationship: RO:0002202 UBERON:0007376 ! develops from outer epithelium [Term] id: UBERON:0001002 name: cuticle namespace: uberon def: "Tough but flexible, non-mineral outer coverings of an organism, or parts of an organism, that provide protection. Cuticles are non-homologous, differing in their origin, structure and chemical composition[WP]." [http://sourceforge.net/tracker/?func=detail&aid=3348965&group_id=36855&atid=440764, Wikipedia:Cuticle] xref: BTO:0001600 xref: Wikipedia:Cuticle is_a: UBERON:0000476 ! acellular anatomical structure relationship: RO:0002160 NCBITaxon:6072 {source="Rieger - Evolution of the Cuticle in the Lower Eumetazoa"} ! only in taxon Eumetazoa [Term] id: UBERON:0001003 name: skin epidermis namespace: uberon def: "The outer epithelial layer of the skin that is superficial to the dermis." [http://orcid.org/0000-0002-6601-2165, ISBN:0073040584] synonym: "vertebrate epidermis" EXACT [] xref: AAO:0000143 xref: BTO:0000404 xref: CALOHA:TS-0283 xref: EFO:0000954 xref: EMAPA:17528 xref: EV:0100153 xref: FMA:70596 xref: GAID:932 xref: MA:0000153 xref: MAT:0000154 xref: MESH:D004817 xref: MIAA:0000154 xref: NCIT:C12708 xref: SCTID:361694003 xref: TAO:0000105 xref: UMLS:C0014520 {source="ncithesaurus:Epidermis"} xref: VHOG:0000077 xref: Wikipedia:Epidermis_(skin) xref: XAO:0000028 xref: ZFA:0000105 is_a: UBERON:0007376 ! outer epithelium is_a: UBERON:3000961 ! external integument structure intersection_of: UBERON:0007376 ! outer epithelium intersection_of: BFO:0000050 UBERON:0002097 ! part of skin of body relationship: BFO:0000050 UBERON:0002097 ! part of skin of body relationship: RO:0002220 UBERON:0002067 ! adjacent to dermis relationship: RO:0002285 UBERON:0003055 ! developmentally replaces periderm [Term] id: UBERON:0001004 name: respiratory system namespace: uberon def: "Functional system which consists of structures involved in respiration." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Respiratory_system] synonym: "apparatus respiratorius" EXACT [] synonym: "respiratory system" EXACT [] xref: AAO:0000541 xref: BTO:0000203 xref: CALOHA:TS-1319 xref: EFO:0000804 xref: EHDAA2:0001604 xref: EHDAA:2203 xref: EMAPA:16727 xref: EV:0100036 xref: FMA:7158 xref: GAID:78 xref: MA:0000327 xref: MAT:0000030 xref: MESH:D012137 xref: MIAA:0000030 xref: NCIT:C12779 xref: SCTID:278197002 xref: TAO:0000272 xref: UMLS:C0035237 {source="ncithesaurus:Respiratory_System"} xref: VHOG:0000202 xref: Wikipedia:Respiratory_system xref: XAO:0000117 xref: ZFA:0000272 is_a: UBERON:0000467 ! anatomical system intersection_of: UBERON:0000467 ! anatomical system intersection_of: RO:0002215 GO:0007585 ! capable of respiratory gaseous exchange by respiratory system disjoint_from: UBERON:0001007 ! digestive system disjoint_from: UBERON:0001009 ! circulatory system disjoint_from: UBERON:0001016 ! nervous system disjoint_from: UBERON:0001434 ! skeletal system disjoint_from: UBERON:0002204 ! musculoskeletal system disjoint_from: UBERON:0002294 ! biliary system disjoint_from: UBERON:0002330 ! exocrine system disjoint_from: UBERON:0002390 ! hematopoietic system disjoint_from: UBERON:0002405 ! immune system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:8450002 ! excretory system relationship: RO:0002160 NCBITaxon:33213 ! only in taxon Bilateria relationship: RO:0002215 GO:0003016 ! capable of respiratory system process relationship: RO:0002215 GO:0007585 ! capable of respiratory gaseous exchange by respiratory system relationship: RO:0002492 UBERON:0000066 ! existence ends during fully formed stage property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/5/5e/Respiratory_system_complete_en.svg" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.0/VH_F_Lung.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Lung.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Lung.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.4/3d-vh-f-lung.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.4/3d-vh-m-lung.glb" xsd:anyURI [Term] id: UBERON:0001005 name: respiratory airway namespace: uberon def: "An airway through which respiratory air passes in organisms." [Wikipedia:Trachea] xref: FMA:265130 xref: SCTID:361380005 xref: Wikipedia:Trachea is_a: UBERON:0003103 ! compound organ is_a: UBERON:0004111 ! anatomical conduit relationship: BFO:0000050 UBERON:0001004 ! part of respiratory system relationship: channel_for UBERON:0034874 ! air in respiratory system property_value: IAO:0000232 "This class generically groups trachea and analagous structures throughout metazoa. Consider renaming, as the term could be taken to mean lumen of tracheal system (e.g. in SNOMED). As a grouping class this is quite vague, as it is not clear where the airway begins and ends" xsd:string [Term] id: UBERON:0001007 name: digestive system namespace: uberon def: "Anatomical system that has as its parts the organs devoted to the ingestion, digestion, and assimilation of food and the discharge of residual wastes." [FB:gg, NLM:alimentary+system, Wikipedia:Digestive_system] xref: AAO:0000129 xref: BILA:0000082 xref: BTO:0000058 xref: CALOHA:TS-1293 xref: EFO:0000793 xref: EV:0100056 xref: FMA:7152 xref: GAID:278 xref: galen:DigestiveSystem xref: MA:0002431 xref: MAT:0000018 xref: MESH:D004064 xref: MIAA:0000018 xref: ncithesaurus:Digestive_System xref: SCTID:278859004 xref: TADS:0000170 xref: TAO:0000339 xref: WBbt:0005748 xref: Wikipedia:Digestive_system xref: XAO:0000125 xref: ZFA:0000339 is_a: UBERON:0000467 ! anatomical system intersection_of: UBERON:0000467 ! anatomical system intersection_of: RO:0002215 GO:0022600 ! capable of digestive system process disjoint_from: UBERON:0001009 ! circulatory system disjoint_from: UBERON:0001016 ! nervous system disjoint_from: UBERON:0001434 ! skeletal system disjoint_from: UBERON:0002204 ! musculoskeletal system disjoint_from: UBERON:0002294 ! biliary system disjoint_from: UBERON:0002330 ! exocrine system disjoint_from: UBERON:0002390 ! hematopoietic system disjoint_from: UBERON:0002405 ! immune system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:8450002 ! excretory system relationship: RO:0002215 GO:0022600 ! capable of digestive system process relationship: RO:0002492 UBERON:0000066 ! existence ends during fully formed stage [Term] id: UBERON:0001008 name: renal system namespace: uberon def: "The renal system in an anatomical system that maintains fluid balance and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products." [DOI:10.1371/journal.pone.0099864, GO:0072001] synonym: "systema urinaria" EXACT [FMA:7159] synonym: "systema urinarium" EXACT [BTO:0003092] synonym: "urinary system" EXACT [] synonym: "urinary tract" EXACT [] xref: AAO:0010257 xref: BILA:0000015 xref: BTO:0001244 xref: BTO:0003092 xref: CALOHA:TS-1323 xref: EFO:0000803 xref: EHDAA2:0001601 xref: EHDAA:5901 xref: EMAPA:17366 xref: EV:0100095 xref: FMA:7159 xref: GAID:391 xref: galen:UrinaryTract xref: MA:0000325 xref: MAT:0000027 xref: MESH:D014551 xref: MIAA:0000027 xref: NCIT:C12413 xref: SCTID:362204003 xref: TADS:0000162 xref: TAO:0000163 xref: UMLS:C1508753 {source="ncithesaurus:Urinary_System"} xref: VHOG:0000723 xref: WBbt:0005736 xref: Wikipedia:Excretory_system xref: XAO:0000143 xref: ZFA:0000163 is_a: UBERON:8450002 ! excretory system intersection_of: UBERON:8450002 ! excretory system intersection_of: RO:0002215 GO:0097254 ! capable of renal tubular secretion relationship: RO:0002160 NCBITaxon:6072 ! only in taxon Eumetazoa relationship: RO:0002215 GO:0097254 ! capable of renal tubular secretion relationship: RO:0002492 UBERON:0000066 ! existence ends during fully formed stage [Term] id: UBERON:0001009 name: circulatory system namespace: uberon def: "Organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis[WP]." [Wikipedia:Circulatory_system] xref: AAO:0000959 xref: CALOHA:TS-2103 xref: VHOG:0001248 xref: Wikipedia:Circulatory_system is_a: UBERON:0000467 ! anatomical system disjoint_from: UBERON:0001016 ! nervous system disjoint_from: UBERON:0001434 ! skeletal system disjoint_from: UBERON:0002204 ! musculoskeletal system disjoint_from: UBERON:0002294 ! biliary system disjoint_from: UBERON:0002330 ! exocrine system disjoint_from: UBERON:0002390 ! hematopoietic system disjoint_from: UBERON:0002405 ! immune system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:8450002 ! excretory system relationship: RO:0002160 NCBITaxon:33213 ! only in taxon Bilateria relationship: RO:0002215 GO:0003013 ! capable of circulatory system process relationship: RO:0002492 UBERON:0000066 ! existence ends during fully formed stage property_value: IAO:0000232 "the cardiovascular system and the lymphatic system are parts of the circulatory system" xsd:string property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/2/29/Circulatory_System_en.svg" xsd:anyURI [Term] id: UBERON:0001013 name: adipose tissue namespace: uberon def: "Portion of connective tissue composed of adipocytes enmeshed in areolar tissue." [http://orcid.org/0000-0002-6601-2165, MESH:A10.165.114, MGI:cwg, MP:0000003, Wikipedia:Adipose_tissue] synonym: "fat" EXACT [MA:0000009] synonym: "fat tissue" EXACT [] synonym: "fatty tissue" EXACT [] xref: AAO:0000001 xref: AEO:000020 xref: BTO:0001487 xref: CALOHA:TS-0013 xref: EFO:0000790 xref: EHDAA2:0003120 xref: EMAPA:35112 xref: EV:0100381 xref: FMA:20110 xref: GAID:920 xref: galen:FattyTissue xref: MA:0000009 xref: MAT:0000015 xref: MESH:D000273 xref: MIAA:0000015 xref: NCIT:C12472 xref: SCTID:55603005 xref: TAO:0002134 xref: UMLS:C0001527 {source="ncithesaurus:Adipose_Tissue"} xref: VHOG:0001284 xref: Wikipedia:Adipose_tissue xref: XAO:0003049 xref: ZFA:0005345 is_a: UBERON:0011822 {source="FMA"} ! dense irregular connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: RO:0002473 CL:0000136 ! composed primarily of adipocyte disjoint_from: UBERON:0003714 ! neural tissue relationship: RO:0002473 CL:0000136 ! composed primarily of adipocyte [Term] id: UBERON:0001015 name: musculature namespace: uberon def: "A subdivision of the muscular system corresponding to a subdisivision of an organism." [https://orcid.org/0000-0002-6601-2165, Wikipedia:Muscular_system] synonym: "muscle group" EXACT [] synonym: "muscles set" EXACT [] synonym: "musculature" EXACT [] synonym: "set of muscles" EXACT [FMA:32558] synonym: "set of skeletal muscles" EXACT [MA:0000165] xref: AAO:0011066 xref: BTO:0000887 xref: EFO:0001949 xref: EMAPA:32715 xref: EMAPA:35577 xref: FMA:32558 xref: MA:0000165 xref: NCIT:C13056 xref: TAO:0000548 xref: UMLS:C0026845 {source="ncithesaurus:Muscle"} xref: VSAO:0005038 xref: WBbt:0005737 xref: Wikipedia:Muscular_system xref: ZFA:0000548 is_a: UBERON:0011216 ! organ system subdivision relationship: BFO:0000050 UBERON:0000383 ! part of musculature of body relationship: RO:0002473 UBERON:0001630 ! composed primarily of muscle organ property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/e/e5/Muscles_anterior_labeled.png" xsd:anyURI [Term] id: UBERON:0001016 name: nervous system namespace: uberon def: "The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior [CUMBO]." [BIRNLEX:844, ISBN:0-14-051288-8, ISBN:3110148986, NLM:nervous+system, WB:rynl, Wikipedia:Nervous_system, ZFIN:curator] synonym: "neurological system" EXACT [GO:0050877] xref: AAO:0000324 xref: BILA:0000079 xref: BIRNLEX:844 xref: BTO:0001484 xref: CALOHA:TS-1313 xref: EFO:0000802 xref: EHDAA2:0001246 xref: EHDAA:826 xref: EMAPA:16469 xref: EV:0100162 xref: FMA:7157 xref: GAID:466 xref: MA:0000016 xref: MAT:0000026 xref: MESH:D009420 xref: MIAA:0000026 xref: NCIT:C12755 xref: neuronames:3236 xref: SCTID:278196006 xref: TAO:0000396 xref: UMLS:C0027763 {source="ncithesaurus:Nervous_System"} xref: VHOG:0000402 xref: WBbt:0005735 xref: Wikipedia:Nervous_system xref: XAO:0000177 xref: ZFA:0000396 is_a: UBERON:0000467 ! anatomical system disjoint_from: UBERON:0001434 ! skeletal system disjoint_from: UBERON:0002204 ! musculoskeletal system disjoint_from: UBERON:0002294 ! biliary system disjoint_from: UBERON:0002330 ! exocrine system disjoint_from: UBERON:0002390 ! hematopoietic system disjoint_from: UBERON:0002405 ! immune system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:8450002 ! excretory system relationship: BFO:0000051 CL:0000540 ! has part neuron relationship: RO:0002160 NCBITaxon:6072 ! only in taxon Eumetazoa relationship: RO:0002215 GO:0050877 ! capable of nervous system process relationship: RO:0002473 CL:0002319 ! composed primarily of neural cell relationship: RO:0002492 UBERON:0000066 ! existence ends during fully formed stage relationship: RO:0002495 UBERON:0016880 {source="Bgee:AN"} ! immediate transformation of future nervous system property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/b/b2/TE-Nervous_system_diagram.svg" xsd:anyURI property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/b/ba/Nervous_system_diagram.png" xsd:anyURI [Term] id: UBERON:0001017 name: central nervous system namespace: uberon def: "The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord." [GO:0021551, http://www.frontiersinzoology.com/content/7/1/29, https://sourceforge.net/p/geneontology/ontology-requests/11422/] xref: AAO:0000090 xref: BAMS:CNS xref: BILA:0000080 xref: BIRNLEX:1099 xref: BTO:0000227 xref: CALOHA:TS-0150 xref: EFO:0000908 xref: EHDAA2:0000225 xref: EHDAA:828 xref: EMAPA:16470 xref: EMAPA:16754 xref: EV:0100163 xref: FMA:55675 xref: GAID:570 xref: MA:0000167 xref: MAT:0000457 xref: MESH:D002490 xref: NCIT:C12438 xref: neuronames:854 xref: SCTID:278199004 xref: TAO:0000012 xref: UMLS:C0927232 {source="ncithesaurus:Central_Nervous_System", source="BIRNLEX:1099"} xref: VHOG:0000293 xref: Wikipedia:Central_nervous_system xref: XAO:0000215 xref: ZFA:0000012 is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0011216 {source="FBbt", source="cjm"} ! organ system subdivision relationship: BFO:0000050 UBERON:0001016 ! part of nervous system relationship: RO:0002160 NCBITaxon:33213 ! only in taxon Bilateria relationship: RO:0002495 UBERON:0016879 {source="Bgee:AN"} ! immediate transformation of future central nervous system [Term] id: UBERON:0001021 name: nerve namespace: uberon def: "An enclosed, cable-like bundle of axons in the peripheral nervous system originating in a nerve root in the central nervous system (or a condensed nervous structure) connecting with peripheral structures." [FBbt:00005105, http://orcid.org/0000-0002-6601-2165] synonym: "peripheral nerve" EXACT [http://orcid.org/0000-0002-6601-2165] xref: AAO:0011070 xref: AEO:0000137 xref: BAMS:n xref: BIRNLEX:1615 xref: BSA:0000098 xref: BTO:0000925 xref: BTO:0001027 xref: CALOHA:TS-0772 xref: EHDAA2:0003137 xref: EHDAA:2851 xref: EHDAA:3776 xref: EHDAA:4657 xref: EMAPA:32808 xref: EMAPA:32815 xref: EV:0100371 xref: FMA:65132 xref: FMA:65239 xref: GAID:747 xref: GAID:758 xref: galen:Nerve xref: MA:0000217 xref: MA:0000228 xref: MESH:D010525 xref: NCIT:C12466 xref: NCIT:C12768 xref: NLX:147826 xref: SCTID:244457007 xref: SCTID:256864008 xref: TAO:0007009 xref: UMLS:C0027740 {source="ncithesaurus:Nerve"} xref: UMLS:C0031119 {source="ncithesaurus:Peripheral_Nerve"} xref: VHOG:0000901 xref: Wikipedia:Nervous_system xref: XAO:0000204 xref: XAO:0003047 xref: ZFA:0007009 is_a: UBERON:0000122 {source="FBbt"} ! neuron projection bundle relationship: BFO:0000050 UBERON:0000010 ! part of peripheral nervous system relationship: RO:0000086 PATO:0002045 ! has quality dendritic relationship: RO:0002254 UBERON:0002342 {gci_filler="NCBITaxon:7742", gci_relation="BFO:0000050", source="https://github.com/obophenotype/uberon/wiki/The-neural-crest"} ! has developmental contribution from neural crest [Term] id: UBERON:0001027 name: sensory nerve namespace: uberon def: "A nerve that transmits from sensory receptors on the surface of the body to the central nervous system." [UBERON:cjm, Wikipedia:Sensory_nerve] xref: AEO:0000201 xref: EHDAA2:0003200 xref: FMA:5868 xref: Wikipedia:Sensory_nerve is_a: UBERON:0001021 ! nerve relationship: BFO:0000051 CL:0000526 {source="AEO"} ! has part afferent neuron [Term] id: UBERON:0001032 name: sensory system namespace: uberon def: "Anatomical system that overlaps the nervous system and is responsible for receiving and processing sensory information." [Wikipedia:Sensory_system] synonym: "sense organ subsystem" EXACT [] synonym: "sense organs" EXACT [FMA:75259] synonym: "sense organs set" EXACT [FMA:75259] synonym: "sensory subsystem" EXACT [] xref: AAO:0000555 xref: BAMS:SEN xref: BILA:0000099 xref: EFO:0000805 xref: EHDAA2:0003094 xref: EMAPA:16192 xref: FMA:75259 xref: MA:0002442 xref: MAT:0000031 xref: MIAA:0000031 xref: NLXANAT:090816 xref: TAO:0000282 xref: VHOG:0001674 xref: Wikipedia:Sensory_system xref: XAO:0003194 xref: ZFA:0000282 is_a: UBERON:0015203 ! non-connected functional system relationship: BFO:0000050 UBERON:0004456 ! part of entire sense organ system relationship: RO:0002131 UBERON:0001016 ! overlaps nervous system relationship: RO:0002216 GO:0007600 ! capable of part of sensory perception property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/c/c0/Gray722.png" xsd:anyURI [Term] id: UBERON:0001040 name: yolk sac namespace: uberon def: "A sac-like expansion of the ventral wall of the intestine, narrowed into a yolk stalk near the body[Hyman's]. Membranous sac attached to an embryo, providing early nourishment in the form of yolk in bony fishes, sharks, reptiles, birds, and primitive mammals. It functions as the developmental circulatory system of the human embryo, before internal circulation begins. In the mouse, the yolk sac is the first site of blood formation, generating primitive macrophages and erythrocytes[WP]." [Wikipedia:Yolk_sac] xref: BTO:0001471 xref: CALOHA:TS-1130 xref: EFO:0003078 xref: EHDAA2:0002212 xref: EHDAA:164 xref: EMAPA:16085 xref: FMA:87180 xref: GAID:1301 xref: MESH:D015017 xref: NCIT:C14128 xref: SCTID:362845002 xref: UMLS:C0043425 {source="ncithesaurus:Yolk_Sac"} xref: VHOG:0000830 xref: Wikipedia:Yolk_sac is_a: UBERON:0005292 ! extraembryonic tissue is_a: UBERON:0005631 ! extraembryonic membrane is_a: UBERON:0007499 {source="EHDAA2"} ! epithelial sac relationship: RO:0002254 UBERON:0000925 {source="ISBN:0073040584"} ! has developmental contribution from endoderm relationship: RO:0002254 UBERON:0004872 {source="ISBN:0073040584"} ! has developmental contribution from splanchnic layer of lateral plate mesoderm property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/1/17/Gray22.png" xsd:anyURI [Term] id: UBERON:0001041 name: foregut namespace: uberon def: "Anterior subdivision of a digestive tract." [http://orcid.org/0000-0002-6601-2165] xref: AAO:0011042 xref: BILA:0000085 xref: BTO:0000507 xref: EHDAA2:0000557 xref: EHDAA:520 xref: EMAPA:16548 xref: FMA:45616 xref: MA:0001526 xref: NCIT:C34180 xref: SCTID:361409009 xref: TGMA:0001014 xref: UMLS:C0231051 {source="ncithesaurus:Foregut"} xref: VHOG:0000285 xref: Wikipedia:Foregut xref: XAO:0000232 is_a: UBERON:0004921 ! subdivision of digestive tract property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/9/9a/Gray27.png" xsd:anyURI [Term] id: UBERON:0001042 name: chordate pharynx namespace: uberon def: "A portion of the respiratory and digestive tracts; its distal limit is the superior part of the esophagus and it connects the nasal and oral cavities with the esophagus and larynx; it contains the valleculae and the pyriform recesses; its upper limits are the nasal cavity and cranial base.[FEED]." [http://www.feedexp.org] xref: AAO:0000967 xref: BTO:0001049 xref: CALOHA:TS-0785 xref: EFO:0000836 xref: EHDAA2:0001458 xref: EHDAA:2947 xref: EMAPA:16706 xref: EV:0100065 xref: FMA:46688 xref: GAID:155 xref: galen:Pharynx xref: MA:0000432 xref: MESH:D010614 xref: NCIT:C12425 xref: SCTID:181211006 xref: TAO:0000056 xref: UMLS:C0031354 {source="ncithesaurus:Pharynx"} xref: VHOG:0000462 xref: Wikipedia:Pharynx xref: XAO:0003227 xref: ZFA:0000056 is_a: UBERON:0006562 ! pharynx relationship: BFO:0000050 UBERON:0001004 ! part of respiratory system relationship: distally_connected_to UBERON:0001043 {gci_filler="NCBITaxon:7742", gci_relation="BFO:0000050"} ! esophagus relationship: RO:0002150 UBERON:0001043 {gci_filler="NCBITaxon:7742", gci_relation="BFO:0000050"} ! continuous with esophagus relationship: RO:0002160 NCBITaxon:7711 ! only in taxon Chordata relationship: RO:0002202 UBERON:0009145 {source="EHDAA2"} ! develops from pharyngeal region of foregut relationship: RO:0002551 UBERON:0008895 {gci_filler="NCBITaxon:89593", gci_relation="BFO:0000050"} ! has skeleton splanchnocranium [Term] id: UBERON:0001043 name: esophagus namespace: uberon def: "Tube that connects the pharynx to the stomach. In mammals, the oesophagus connects the buccal cavity with the stomach. The stratified squamous non-keratinised epithelium lining the buccal cavity is continued through the pharynx down into the oesophagus. The lowest part of the oesophagus (ca. 2 cm) is lined with gastric mucosa and covered by peritoneum. The main body of the oesophagus is lined with small, simple mucous glands. Each gland opens into the lumen by a long duct which pierces the muscularis mucosae (Wilson and Washington, 1989). A sphincter is situated at the point where the oesophagus enters the stomach to prevent gastro-oesophageal reflux, i.e. to prevent acidic gastric contents from reaching stratified epithelia of the oesophagus, where they can cause inflammation and irritation (Wilson and Washington, 1989; Brown et al., 1993)." [http://www.rivm.nl/interspeciesinfo/inter/oesophagus/, Wikipedia:Esophagus] synonym: "gullet" EXACT [] synonym: "oesophagus" EXACT [] xref: AAO:0000145 xref: ANISEED:1235301 xref: BTO:0000959 xref: CALOHA:TS-0700 xref: EFO:0000835 xref: EHDAA2:0001285 xref: EHDAA:2937 xref: EMAPA:16833 xref: EV:0100069 xref: FMA:7131 xref: GAID:291 xref: galen:Esophagus xref: MA:0000352 xref: MAT:0000048 xref: MESH:D004947 xref: MIAA:0000048 xref: NCIT:C12389 xref: SCTID:181245004 xref: TAO:0000204 xref: UMLS:C0014876 {source="ncithesaurus:Esophagus"} xref: VHOG:0000450 xref: Wikipedia:Esophagus xref: XAO:0000127 xref: ZFA:0000204 is_a: UBERON:0004921 ! subdivision of digestive tract is_a: UBERON:0005178 ! thoracic cavity element is_a: UBERON:0013765 ! digestive system element relationship: BFO:0000050 RO:0002577 ! part of system relationship: BFO:0000050 UBERON:0004908 ! part of upper digestive tract relationship: proximally_connected_to UBERON:0001042 ! chordate pharynx relationship: RO:0002202 UBERON:0001041 ! develops from foregut property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/d/d4/Illu01_head_neck.jpg" xsd:anyURI [Term] id: UBERON:0001045 name: midgut namespace: uberon def: "Middle subdivision of a digestive tract[CJM]. In vertebrates: The middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine[GO]." [GO:0007494, Wikipedia:Midgut] xref: BILA:0000086 xref: BTO:0000863 xref: EFO:0001950 xref: EHDAA2:0001185 xref: EHDAA:983 xref: EMAPA:16255 xref: FMA:45617 xref: MA:0001564 xref: NCIT:C34210 xref: SCTID:361410004 xref: TGMA:0001036 xref: UMLS:C0231052 {source="ncithesaurus:Midgut"} xref: VHOG:0000290 xref: Wikipedia:Midgut xref: XAO:0000103 is_a: UBERON:0004921 ! subdivision of digestive tract relationship: BFO:0000050 RO:0002577 ! part of system relationship: proximally_connected_to UBERON:0001041 ! foregut property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/3/3d/Illu_small_intestine.jpg" xsd:anyURI [Term] id: UBERON:0001046 name: hindgut namespace: uberon def: "The caudalmost subdivision of a digestive tract." [http://orcid.org/0000-0002-6601-2165] xref: AAO:0011052 xref: BILA:0000087 xref: BTO:0000510 xref: EHDAA2:0000779 xref: EHDAA:975 xref: EMAPA:16715 xref: FMA:45618 xref: MA:0001527 xref: NCIT:C34188 xref: SCTID:362856002 xref: TGMA:0001020 xref: UMLS:C0231053 {source="ncithesaurus:Hindgut"} xref: VHOG:0000459 xref: Wikipedia:Hindgut xref: XAO:0000104 is_a: UBERON:0004921 ! subdivision of digestive tract relationship: BFO:0000050 RO:0002577 ! part of system relationship: proximally_connected_to UBERON:0001045 ! midgut relationship: RO:0002202 UBERON:0003104 {source="Wikipedia"} ! develops from mesenchyme property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/f/f7/Gray472.png" xsd:anyURI [Term] id: UBERON:0001048 name: primordium namespace: uberon def: "Primordia are populations of contiguous cells that are morphologically distinct and already correspond in extent to a later organ/tissue[FBbt, Hartenstein, V. (2004)]." [BTO:0001886, FB:DJS, FB:FBrf0089570, http://flybase.org/reports/FBrf0178740.html] xref: AEO:0000171 xref: BTO:0001886 xref: EFO:0001652 xref: EHDAA2:0003171 xref: FMA:86589 xref: MAT:0000482 xref: NCIT:C34275 xref: UMLS:C0678727 {source="ncithesaurus:Primordium"} xref: Wikipedia:Primordium xref: XAO:0003043 is_a: UBERON:0005423 {source="EHDAA2"} ! developing anatomical structure relationship: BFO:0000050 UBERON:0000468 ! part of multicellular organism [Term] id: UBERON:0001049 name: neural tube namespace: uberon def: "In the developing vertebrate, the neural tube is the embryo's precursor to the central nervous system, which comprises the brain and spinal cord. The neural groove gradually deepens as the neural folds become elevated, and ultimately the folds meet and coalesce in the middle line and convert the groove into a closed tube, the neural tube or neural canal (which strictly speaking is the center of the neural tube), the ectodermal wall of which forms the rudiment of the nervous system. [WP,unvetted]." [Wikipedia:Neural_tube] xref: AAO:0010617 xref: BTO:0001057 xref: CALOHA:TS-2371 xref: DHBA:10154 xref: EHDAA2:0001254 xref: EHDAA:2869 xref: EHDAA:908 xref: EMAPA:16164 xref: EMAPA:16757 xref: FMA:293882 xref: MAT:0000069 xref: MIAA:0000069 xref: NCIT:C34226 xref: neuronames:1365 xref: SCTID:362852000 xref: TAO:0001135 xref: UMLS:C0231024 {source="ncithesaurus:Neural_Tube"} xref: VHOG:0000307 xref: Wikipedia:Neural_tube xref: XAO:0003204 xref: ZFA:0001135 is_a: UBERON:0003914 {source="EHDAA2"} ! epithelial tube is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0010371 ! ecto-epithelium is_a: UBERON:0016879 ! future central nervous system relationship: RO:0002202 UBERON:0005068 ! develops from neural rod property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png" xsd:anyURI [Term] id: UBERON:0001052 name: rectum namespace: uberon def: "The terminal portion of the intestinal tube, terminating with the anus." [http://orcid.org/0000-0002-6601-2165, ISBN:0-683-40008-8, MP:0000492] synonym: "terminal portion of intestine" EXACT [] xref: AAO:0010401 xref: BTO:0001158 xref: CALOHA:TS-1180 xref: EFO:0000848 xref: EHDAA2:0001592 xref: EHDAA:5836 xref: EMAPA:17896 xref: EV:0100081 xref: FMA:14544 xref: GAID:311 xref: galen:Rectum xref: MA:0000336 xref: MAT:0000050 xref: MESH:D012007 xref: MIAA:0000050 xref: NCIT:C12390 xref: SCTID:181261002 xref: UMLS:C0034896 {source="ncithesaurus:Rectum"} xref: VHOG:0001751 xref: Wikipedia:Rectum xref: XAO:0000238 is_a: UBERON:0004921 ! subdivision of digestive tract relationship: BFO:0000050 UBERON:0006866 ! part of terminal part of digestive tract relationship: BFO:0000050 UBERON:0012361 {source="EHDAA2"} ! part of internal anal region relationship: BSPO:0001108 UBERON:0000059 {source="ISBN:0073040584"} ! distalmost part of large intestine relationship: RO:0002150 UBERON:0001159 ! continuous with sigmoid colon relationship: RO:0002433 UBERON:0000059 ! contributes to morphology of large intestine property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/7/75/Anorectum.gif" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/SBU_F_Intestine_Large.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/SBU_M_Intestine_Large.glb" xsd:anyURI [Term] id: UBERON:0001062 name: anatomical entity namespace: uberon def: "Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species." [FMA:62955, http://orcid.org/0000-0001-9114-8737] xref: AAO:0010841 xref: AEO:0000000 xref: BFO:0000004 xref: BILA:0000000 xref: BIRNLEX:6 xref: CARO:0000000 xref: EHDAA2:0002229 xref: FMA:62955 xref: HAO:0000000 xref: MA:0000001 xref: NCIT:C12219 xref: TAO:0100000 xref: TGMA:0001822 xref: UMLS:C1515976 {source="ncithesaurus:Anatomic_Structure_System_or_Substance"} xref: WBbt:0000100 xref: XAO:0000000 xref: ZFA:0100000 is_a: BFO:0000004 ! independent continuant relationship: BFO:0000050 UBERON:0003942 {gci_relation="RO:0002216", gci_filler="GO:0050975"} ! part of somatosensory system relationship: BFO:0000050 UBERON:0003942 {gci_relation="RO:0002216", gci_filler="GO:0019233"} ! part of somatosensory system [Term] id: UBERON:0001064 name: ventral pancreatic duct namespace: uberon def: "A duct joining the pancreas to the common bile duct to supply pancreatic juices which aid in digestion provided by the exocrine pancreas. The pancreatic duct joins the common bile duct just prior to the ampulla of Vater, after which both ducts perforate the medial side of the second portion of the duodenum at the major duodenal papilla." [Wikipedia:Pancreatic_duct] synonym: "chief pancreatic duct" EXACT [FMA:16003] synonym: "duct of Wirsung" EXACT [Wikipedia:Pancreatic_duct] synonym: "main pancreatic duct" EXACT [MA:0000126] xref: BTO:0002362 xref: EHDAA2:0001396 xref: EHDAA:6905 xref: EMAPA:17510 xref: FMA:16003 xref: GAID:337 xref: MA:0000126 xref: MESH:D010183 xref: NCIT:C12272 xref: RETIRED_EHDAA2:0002177 xref: SCTID:245385001 xref: UMLS:C0030288 {source="ncithesaurus:Pancreatic_Duct"} xref: VHOG:0000256 xref: Wikipedia:Pancreatic_duct is_a: UBERON:0000025 ! tube is_a: UBERON:0007329 {source="FMA"} ! pancreatic duct relationship: channel_for UBERON:0001970 ! bile relationship: channels_into UBERON:0004913 ! hepatopancreatic ampulla relationship: RO:0002150 UBERON:0001174 ! continuous with common bile duct relationship: RO:0002202 UBERON:0003924 {source="EHDAA2"} ! develops from ventral pancreatic bud property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/1/15/Gray1100.png" xsd:anyURI [Term] id: UBERON:0001068 name: skin of back namespace: uberon def: "A zone of skin that is part of a back [Automatically generated definition]." [OBOL:automatic] synonym: "back skin" EXACT [] synonym: "back zone of skin" EXACT [OBOL:automatic] synonym: "skin, dorsal region" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "zone of skin of back" EXACT [OBOL:automatic] xref: EMAPA:36392 xref: FMA:10462 xref: FMA:22985 xref: MA:0000498 xref: SCTID:181492002 is_a: UBERON:0001085 {source="MA"} ! skin of trunk intersection_of: UBERON:0000014 ! zone of skin intersection_of: BFO:0000050 UBERON:0001137 ! part of dorsum relationship: BFO:0000050 UBERON:0011270 {source="MA"} ! part of dorsal trunk [Term] id: UBERON:0001070 name: external carotid artery namespace: uberon def: "A terminal branch of the left or right common carotid artery which supplies oxygenated blood to to the throat, neck glands, tongue, face, mouth, ear, scalp and dura mater of the meninges[MP]." [MGI:anna] synonym: "external carotid" EXACT [AAO:0010218] xref: AAO:0010218 xref: AAO:0010416 xref: BTO:0004696 xref: EFO:0001953 xref: EHDAA2:0000461 xref: EMAPA:18611 xref: FMA:10635 xref: GAID:480 xref: MA:0001929 xref: MESH:D002342 xref: NCIT:C32551 xref: SCTID:362044002 xref: UMLS:C0007275 {source="ncithesaurus:External_Carotid_Artery"} xref: VHOG:0000265 xref: Wikipedia:External_carotid_artery xref: XAO:0000345 is_a: UBERON:0005396 {source="MA"} ! carotid artery segment relationship: RO:0002202 UBERON:0001530 {source="EHDAA2"} ! develops from common carotid artery plus branches relationship: RO:0002380 UBERON:0001530 {source="FMA"} ! branching part of common carotid artery plus branches property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/1/13/External_carotid_a.gif" xsd:anyURI [Term] id: UBERON:0001071 name: superficial cervical artery namespace: uberon def: "It ascends beneath the anterior margin of the trapezius, distributing branches to it, and to the neighboring muscles and lymph glands in the neck, and anastomosing with the superficial branch of the descending branch of the occipital artery." [Wikipedia:Superficial_part_of_transverse_cervical_artery] synonym: "superficial branch of transverse cervical artery" EXACT [Wikipedia:Superficial_part_of_transverse_cervical_artery] xref: EMAPA:37117 {source="MA:th"} xref: FMA:10665 xref: MA:0002052 xref: NCIT:C53005 xref: SCTID:161746006 xref: UMLS:C0226271 {source="ncithesaurus:Superficial_Cervical_Artery"} xref: Wikipedia:Superficial_part_of_transverse_cervical_artery is_a: UBERON:0012320 ! cervical artery intersection_of: UBERON:0012320 ! cervical artery intersection_of: BFO:0000050 UBERON:0035549 ! part of vasculature of integument relationship: BFO:0000050 UBERON:0035549 ! part of vasculature of integument relationship: RO:0002170 UBERON:0012324 ! connected to transverse cervical artery [Term] id: UBERON:0001072 name: posterior vena cava namespace: uberon def: "A vein that carries deoxygenated blood from the lower half of the body into the right atrium of the heart." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Inferior_vena_cava] synonym: "inferior caval vein" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "inferior vena cava" EXACT [Wikipedia:Venae_cavae] synonym: "posterior vena cava" EXACT [Wikipedia:Venae_cavae] xref: AAO:0011083 xref: BTO:0002682 xref: EHDAA2:0000611 xref: EMAPA:18416 xref: FMA:10951 xref: GAID:548 xref: galen:InferiorVenaCava xref: MA:0000480 xref: MESH:D014682 xref: NCIT:C12815 xref: SCTID:181369003 xref: UMLS:C0042458 {source="ncithesaurus:Inferior_Vena_Cava"} xref: VHOG:0001194 xref: Wikipedia:Inferior_vena_cava xref: XAO:0000388 is_a: UBERON:0004087 ! vena cava intersection_of: UBERON:0004087 ! vena cava intersection_of: RO:0002179 UBERON:0000154 ! drains posterior region of body disjoint_from: UBERON:0001585 {source="lexical"} ! anterior vena cava relationship: BFO:0000050 RO:0002577 ! part of system relationship: channels_into UBERON:0002078 {gci_filler="NCBITaxon:40674", gci_relation="BFO:0000050"} ! right cardiac atrium relationship: RO:0002170 UBERON:0002078 ! connected to right cardiac atrium relationship: RO:0002179 UBERON:0000154 ! drains posterior region of body relationship: RO:0002202 UBERON:0005487 {gci_filler="NCBITaxon:40674", gci_relation="BFO:0000050", source="Wikipedia:Vitelline_vein"} ! develops from vitelline vein property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/4/4d/Gray577.png" xsd:anyURI [Term] id: UBERON:0001073 name: ileocecal junction namespace: uberon def: "A point along the course of the gastrointestinal tract where the small intestine (ileum) ends as it opens into the cecal portion of the large intestine; occurs usually within the iliac fossa, demarcated internally as the ileocecal orifice." [http://www.medilexicon.com/medicaldictionary.php?t=46539] synonym: "ileocaecal junction" EXACT [] xref: EMAPA:37601 {source="MA:th"} xref: FMA:11338 xref: MA:0000332 xref: SCTID:264021000 is_a: UBERON:8410024 ! intestinal junction intersection_of: UBERON:0007651 ! anatomical junction intersection_of: RO:0002176 UBERON:0000059 ! connects large intestine intersection_of: RO:0002176 UBERON:0002108 ! connects small intestine relationship: RO:0002160 NCBITaxon:7742 ! only in taxon Vertebrata relationship: RO:0002176 UBERON:0000059 ! connects large intestine relationship: RO:0002176 UBERON:0002108 ! connects small intestine [Term] id: UBERON:0001074 name: pericardial cavity namespace: uberon def: "A potential space between the visceral and parietal layers of the pericardium." [Wikipedia:Pericardium] synonym: "cavity of pericardial sac" EXACT [] synonym: "pericardial space" EXACT [Wikipedia:Pericardial_cavity] xref: BSA:0000091 xref: EHDAA2:0001434 xref: EMAPA:16131 xref: EMAPA:16132 xref: FMA:11350 xref: galen:PericardialSpace xref: MA:0000053 xref: NCIT:C38662 xref: SCTID:362027001 xref: TAO:0002220 xref: UMLS:C0225972 {source="ncithesaurus:Pericardial_Cavity"} xref: VHOG:0000556 xref: Wikipedia:Pericardial_cavity xref: ZFA:0001655 is_a: UBERON:0002323 {source="MA"} ! coelemic cavity lumen is_a: UBERON:0035809 ! serous cavity intersection_of: UBERON:0002553 ! anatomical cavity intersection_of: RO:0002572 UBERON:0002406 ! luminal space of pericardial sac relationship: RO:0001015 UBERON:0002409 ! location of pericardial fluid relationship: RO:0002202 UBERON:0003887 {source="Wikipedia"} ! develops from intraembryonic coelom relationship: RO:0002219 UBERON:0002357 ! surrounded by serous pericardium relationship: RO:0002572 UBERON:0002406 ! luminal space of pericardial sac [Term] id: UBERON:0001081 name: endocardium of ventricle namespace: uberon def: "Endocardium that is part of the cardiac ventricle." [ZFIN:curator] synonym: "cardiac ventricle endocardium" EXACT [OBOL:automatic] synonym: "endocardium of cardiac ventricle" EXACT [OBOL:automatic] synonym: "endocardium of heart ventricle" EXACT [OBOL:automatic] synonym: "endocardium of lower chamber of heart" EXACT [OBOL:automatic] synonym: "endocardium of ventricle of heart" EXACT [OBOL:automatic] synonym: "heart ventricle endocardium" EXACT [OBOL:automatic] synonym: "lower chamber of heart endocardium" EXACT [OBOL:automatic] synonym: "ventricle endocardium" EXACT [] synonym: "ventricle of heart endocardium" EXACT [OBOL:automatic] synonym: "ventricular endocardium" EXACT [] xref: EMAPA:32747 xref: FMA:12148 xref: MA:0000079 xref: SCTID:192172004 xref: TAO:0002247 xref: VHOG:0000607 xref: ZFA:0001615 is_a: UBERON:0000487 ! simple squamous epithelium is_a: UBERON:0002165 ! endocardium is_a: UBERON:0012275 ! meso-epithelium intersection_of: UBERON:0002165 ! endocardium intersection_of: BFO:0000050 UBERON:0002082 ! part of cardiac ventricle relationship: BFO:0000050 UBERON:0004784 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! part of heart ventricle wall relationship: RO:0002433 UBERON:0002082 ! contributes to morphology of cardiac ventricle [Term] id: UBERON:0001082 name: epicardium of ventricle namespace: uberon def: "An epicardial layer that lines a cardiac ventricle." [http://orcid.org/0000-0002-6601-2165] synonym: "cardiac ventricle epicardium" EXACT [OBOL:automatic] synonym: "ventricular epicardium" EXACT [] xref: FMA:12150 xref: TAO:0005058 xref: ZFA:0005058 is_a: UBERON:0002348 ! epicardium intersection_of: UBERON:0002348 ! epicardium intersection_of: BFO:0000050 UBERON:0002082 ! part of cardiac ventricle relationship: BFO:0000050 UBERON:0002082 ! part of cardiac ventricle [Term] id: UBERON:0001083 name: myocardium of ventricle namespace: uberon def: "Muscular layer of the cardiac ventricle composed of a compact myocardial layer surrounding the trabecular layer." [ZFIN:curator] synonym: "ventricle myocardium" EXACT [] synonym: "ventricular myocardium" EXACT [] xref: EFO:0003088 xref: EMAPA:32748 xref: FMA:12151 xref: MA:0000082 xref: SCTID:192084000 xref: TAO:0005061 xref: VHOG:0000604 xref: ZFA:0005061 is_a: UBERON:0002349 ! myocardium intersection_of: UBERON:0002349 ! myocardium intersection_of: BFO:0000050 UBERON:0002082 ! part of cardiac ventricle relationship: BFO:0000050 UBERON:0004784 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! part of heart ventricle wall relationship: RO:0002433 UBERON:0002082 ! contributes to morphology of cardiac ventricle [Term] id: UBERON:0001084 name: skin of head namespace: uberon def: "A zone of skin that is part of a head [Automatically generated definition]." [OBOL:automatic] synonym: "adult head zone of skin" EXACT [OBOL:automatic] synonym: "head skin" EXACT [] synonym: "head zone of skin" EXACT [OBOL:automatic] synonym: "zone of skin of adult head" EXACT [OBOL:automatic] synonym: "zone of skin of head" EXACT [OBOL:automatic] xref: FMA:12166 xref: FMA:24756 xref: MA:0000582 xref: NCIT:C52757 xref: SCTID:181484006 xref: UMLS:C0205029 {source="ncithesaurus:Head_Skin"} is_a: UBERON:0012180 ! head or neck skin intersection_of: UBERON:0000014 ! zone of skin intersection_of: BFO:0000050 UBERON:0000033 ! part of head relationship: BFO:0000050 UBERON:0000033 ! part of head [Term] id: UBERON:0001085 name: skin of trunk namespace: uberon def: "A zone of skin that is part of a trunk [Automatically generated definition]." [OBOL:automatic] synonym: "torso zone of skin" EXACT [OBOL:automatic] synonym: "trunk skin" EXACT [] synonym: "trunk zone of skin" EXACT [OBOL:automatic] synonym: "zone of skin of torso" EXACT [OBOL:automatic] synonym: "zone of skin of trunk" EXACT [OBOL:automatic] xref: EMAPA:37278 {source="MA:th"} xref: FMA:12167 xref: FMA:23093 xref: MA:0000517 xref: NCIT:C12295 xref: SCTID:181489001 xref: UMLS:C0205031 {source="ncithesaurus:Skin_of_the_Trunk"} is_a: UBERON:0000014 ! zone of skin intersection_of: UBERON:0000014 ! zone of skin intersection_of: BFO:0000050 UBERON:0002100 ! part of trunk relationship: BFO:0000050 UBERON:0002100 ! part of trunk [Term] id: UBERON:0001087 name: pleural fluid namespace: uberon def: "Transudate contained in the pleural cavity." [FMA:12273] xref: BTO:0003080 xref: FMA:12273 xref: MA:0002532 xref: MAT:0000500 xref: ncithesaurus:Pleural_Fluid xref: Wikipedia:Pleural_fluid is_a: UBERON:0036244 ! secretion of serous membrane intersection_of: UBERON:0007779 ! transudate intersection_of: RO:0001025 UBERON:0002402 ! located in pleural cavity relationship: RO:0001025 UBERON:0002402 ! located in pleural cavity [Term] id: UBERON:0001088 name: urine namespace: uberon def: "Excretion that is the output of a kidney." [https://github.com/geneontology/go-ontology/issues/11025, Wikipedia:Urine] xref: BTO:0001419 xref: CALOHA:TS-1092 xref: EFO:0001939 xref: EMAPA:36554 xref: ENVO:00002047 xref: FMA:12274 xref: GAID:1189 xref: galen:Urine xref: MA:0002545 xref: MAT:0000058 xref: MESH:D014556 xref: MIAA:0000058 xref: NCIT:C13283 xref: UMLS:C0042036 {source="ncithesaurus:Urine"} xref: Wikipedia:Urine is_a: UBERON:0000174 ! excreta intersection_of: UBERON:0000174 ! excreta intersection_of: RO:0003001 UBERON:0002113 ! produced by kidney relationship: RO:0000086 PATO:0001548 {gci_filler="NCBITaxon:40674", gci_relation="BFO:0000050"} ! has quality quality of a liquid relationship: RO:0003001 UBERON:0002113 ! produced by kidney [Term] id: UBERON:0001090 name: synovial fluid namespace: uberon def: "Joint fluid is a transudate of plasma that is actively secreted by synovial cells." [https://www.ncbi.nlm.nih.gov/books/NBK274/] synonym: "joint fluid" EXACT [https://www.ncbi.nlm.nih.gov/books/NBK274/] xref: BTO:0001339 xref: CALOHA:TS-0996 xref: ENVO:02000039 xref: FMA:12277 xref: GAID:265 xref: galen:SynovialFluid xref: MA:0002544 xref: MESH:D013582 xref: NCIT:C33718 xref: TAO:0005154 xref: UMLS:C0039097 {source="ncithesaurus:Synovial_Fluid"} xref: Wikipedia:Synovial_fluid xref: ZFA:0005154 is_a: UBERON:0007779 ! transudate is_a: UBERON:0007794 {source="FMA"} ! secretion of serous gland intersection_of: UBERON:0007779 ! transudate intersection_of: RO:0003001 CL:0000214 ! produced by synovial cell relationship: BFO:0000051 CHEBI:16336 ! has part hyaluronic acid relationship: RO:0001025 UBERON:0007617 ! located in synovial cavity of joint relationship: RO:0003001 CL:0000214 ! produced by synovial cell [Term] id: UBERON:0001092 name: vertebral bone 1 namespace: uberon def: "The first vertebral bone in the vertebral column." [http://orcid.org/0000-0002-6601-2165] synonym: "atlas" EXACT [] synonym: "atlas (CI)" EXACT [] synonym: "atlas vertebra" EXACT [] synonym: "C1 vertebra" EXACT [] synonym: "cervical atlas" EXACT [MP:0011576] synonym: "first cervical vertebra" EXACT [] synonym: "vertebra 1" EXACT [TAO:0001167] xref: AAO:0000709 xref: EHDAA:10606 xref: EMAPA:19431 xref: FMA:12519 xref: GAID:236 xref: MA:0001421 xref: MESH:D001270 xref: NCIT:C32239 xref: SCTID:181818007 xref: TAO:0001167 xref: UMLS:C0004170 {source="ncithesaurus:C1_Vertebra"} xref: Wikipedia:Atlas_(anatomy) xref: ZFA:0001167 is_a: UBERON:0002412 ! vertebra relationship: anteriorly_connected_to UBERON:0001676 {gci_filler="NCBITaxon:40674", gci_relation="BFO:0000050", source="FMA"} ! occipital bone relationship: BFO:0000050 UBERON:0006072 {gci_filler="NCBITaxon:32523", gci_relation="BFO:0000050"} ! part of cervical region of vertebral column relationship: BSPO:0000096 UBERON:0001093 ! anterior to vertebral bone 2 [Term] id: UBERON:0001093 name: vertebral bone 2 namespace: uberon def: "The second vertebral bone in the vertebral column." [http://orcid.org/0000-0002-6601-2165] synonym: "axis (CII)" EXACT [] synonym: "axis vertebra" EXACT [] synonym: "cervical axis" EXACT [MP:0004608] synonym: "vertebra 2" EXACT [ZFA:0001168] xref: EHDAA:10608 xref: EMAPA:19432 xref: FMA:12520 xref: GAID:237 xref: MA:0001422 xref: MESH:D001368 xref: NCIT:C32240 xref: SCTID:181819004 xref: TAO:0001168 xref: UMLS:C0004457 {source="ncithesaurus:C2_Vertebra"} xref: Wikipedia:Axis_(anatomy) xref: ZFA:0001168 is_a: UBERON:0002412 ! vertebra relationship: anteriorly_connected_to UBERON:0001092 {source="FMA"} ! vertebral bone 1 relationship: BFO:0000050 RO:0002577 ! part of system relationship: BFO:0000050 UBERON:0006072 {gci_filler="NCBITaxon:32523", gci_relation="BFO:0000050"} ! part of cervical region of vertebral column [Term] id: UBERON:0001095 name: caudal vertebra namespace: uberon def: "Any vertebral bone that is part of the caudal region of the vertebral column (tail or coccyx)." [http://orcid.org/0000-0002-6601-2165] synonym: "caudal vertebral bone" EXACT [] synonym: "caudal vertebral bone element" EXACT [] synonym: "coccygeal segment" EXACT [] synonym: "coccygeal vertebra" EXACT [FMA:12527] synonym: "fused tail vertebra" EXACT [https://orcid.org/0000-0002-6601-2165] xref: EMAPA:18374 xref: FMA:12527 xref: galen:CoccygealVertebra xref: MA:0000310 xref: MA:0001420 xref: NCIT:C32334 xref: SCTID:361774004 xref: TAO:0000326 xref: UMLS:C0223616 {source="ncithesaurus:Coccygeal_Vertebra"} xref: Wikipedia:Caudal_vertebra xref: XAO:0003079 xref: ZFA:0000326 is_a: UBERON:0002412 ! vertebra is_a: UBERON:0004247 ! bone of dorsum is_a: UBERON:0018142 ! caudal vertebra endochondral element intersection_of: UBERON:0018142 ! caudal vertebra endochondral element intersection_of: RO:0002473 UBERON:0002481 ! composed primarily of bone tissue [Term] id: UBERON:0001096 name: wall of esophagus namespace: uberon def: "An anatomical wall that is part of a esophagus [Automatically generated definition]." [OBOL:automatic] synonym: "anatomical wall of esophagus" EXACT [OBOL:automatic] synonym: "anatomical wall of gullet" EXACT [OBOL:automatic] synonym: "anatomical wall of oesophagus" EXACT [OBOL:automatic] synonym: "esophageal wall" EXACT [] synonym: "esophagus anatomical wall" EXACT [OBOL:automatic] synonym: "esophagus wall" EXACT [] synonym: "gullet anatomical wall" EXACT [OBOL:automatic] synonym: "gullet wall" EXACT [OBOL:automatic] synonym: "oesophagus anatomical wall" EXACT [OBOL:automatic] synonym: "oesophagus wall" EXACT [OBOL:automatic] synonym: "wall of gullet" EXACT [OBOL:automatic] synonym: "wall of oesophagus" EXACT [OBOL:automatic] xref: EMAPA:35326 xref: FMA:12611 xref: MA:0002691 is_a: UBERON:0000328 ! gut wall intersection_of: UBERON:0000060 ! anatomical wall intersection_of: BFO:0000050 UBERON:0001043 ! part of esophagus relationship: BFO:0000050 UBERON:0001043 ! part of esophagus [Term] id: UBERON:0001103 name: diaphragm namespace: uberon def: "A thin musculomebranous barrier that separates the abdominal and thoracic cavities. Often used for breathing control." [MP:0002279] synonym: "diaphragm muscle" EXACT [BTO:0000341] synonym: "diaphragm of thorax" EXACT [] synonym: "thoracic diaphragm" EXACT [] xref: BTO:0000341 xref: CALOHA:TS-0198 xref: EFO:0000937 xref: EHDAA2:0003495 xref: EMAPA:17701 xref: EV:0100376 xref: FMA:13295 xref: GAID:158 xref: MA:0001904 xref: MAT:0000502 xref: MESH:D003964 xref: NCIT:C12702 xref: SCTID:181614006 xref: UMLS:C0011980 {source="ncithesaurus:Diaphragm"} xref: VHOG:0000713 xref: Wikipedia:Thoracid_diaphragm is_a: UBERON:0003830 ! thoracic segment muscle is_a: UBERON:0003831 ! respiratory system muscle relationship: RO:0002005 UBERON:0001884 ! innervated_by phrenic nerve relationship: RO:0002160 NCBITaxon:40674 {source="PMID:23586979"} ! only in taxon Mammalia relationship: RO:0002495 UBERON:0010084 ! immediate transformation of future diaphragm [Term] id: UBERON:0001113 name: lobe of liver namespace: uberon def: "Traditional gross anatomy divided the liver into four lobes based on surface features. The falciform ligament is visible on the front (anterior side) of the liver. This divides the liver into a left anatomical lobe, and a right anatomical lobe." [Wikipedia:Liver#Lobes] synonym: "hepatic lobe" EXACT [] synonym: "liver lobe" EXACT [] synonym: "lobus hepatis" EXACT [] xref: EMAPA:18306 xref: FMA:13361 xref: MA:0000360 xref: NCIT:C49579 xref: SCTID:245378000 xref: UMLS:C0447541 {source="ncithesaurus:Liver_Lobe"} xref: Wikipedia:Liver#Lobes is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0009912 {source="FMA"} ! anatomical lobe relationship: BFO:0000050 UBERON:0002107 ! part of liver [Term] id: UBERON:0001114 name: right lobe of liver namespace: uberon def: "The right lobe is much larger than the left; the proportion between them being as six to one. It occupies the right hypochondrium, and is separated from the left lobe on its upper surface by the falciform ligament; on its under and posterior surfaces by the left sagittal fossa; and in front by the umbilical notch. It is of a somewhat quadrilateral form, its under and posterior surfaces being marked by three fossæ: the porta and the fossæ for the gall-bladder and inferior vena cava, which separate its left part into two smaller lobes; the quadrate and caudate lobes. [WP,unvetted]." [Wikipedia:Right_lobe_of_liver] synonym: "liver right lobe" EXACT [] synonym: "right liver lobe" EXACT [ZFA:0005173] xref: EHDAA2:0001008 xref: EHDAA:4001 xref: EMAPA:18311 xref: FMA:13362 xref: MA:0000363 xref: NCIT:C33481 xref: SCTID:362182008 xref: TAO:0005173 xref: UMLS:C0227481 {source="ncithesaurus:Right_Lobe_of_the_Liver"} xref: VHOG:0001424 xref: Wikipedia:Right_lobe_of_liver xref: ZFA:0005173 is_a: UBERON:0001113 ! lobe of liver property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/a/a3/Gray1087-liver.png" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Liver.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Liver.glb" xsd:anyURI [Term] id: UBERON:0001115 name: left lobe of liver namespace: uberon def: "The left lobe is smaller and more flattened than the right. It is situated in the epigastric and left hypochondriac regions. Its upper surface is slightly convex and is moulded on to the diaphragm; its under surface presents the gastric impression and omental tuberosity. [WP,unvetted]." [Wikipedia:Left_lobe_of_liver] synonym: "left liver lobe" EXACT [] synonym: "liver left lobe" EXACT [] xref: EHDAA2:0001000 xref: EHDAA:3995 xref: EMAPA:18307 xref: FMA:13363 xref: MA:0000361 xref: NCIT:C32965 xref: SCTID:362183003 xref: TAO:0005172 xref: UMLS:C0227486 {source="ncithesaurus:Left_Lobe_of_the_Liver"} xref: VHOG:0001423 xref: Wikipedia:Left_lobe_of_liver xref: ZFA:0005172 is_a: UBERON:0001113 ! lobe of liver property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/a/a3/Gray1087-liver.png" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Liver.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Liver.glb" xsd:anyURI [Term] id: UBERON:0001130 name: vertebral column namespace: uberon def: "Subdivision of skeletal system that consists of all the vertebra and associated skeletal elements and joints in the body[modified from VSAO]." [https://orcid.org/0000-0002-6601-2165, https://sourceforge.net/tracker/?func=detail&aid=3530322&group_id=76834&atid=2257941, VSAO:0000185] xref: AAO:0000699 xref: AAO:0000734 xref: BTO:0000818 xref: EFO:0001369 xref: EHDA:10119 xref: EMAPA:35919 xref: FMA:13478 xref: GAID:106 xref: galen:SpinalColumn xref: MA:0002416 xref: MESH:D013131 xref: NCIT:C12998 xref: NCIT:C33588 xref: NIF_Subcellular:sao1145756102 xref: SCTID:44300000 xref: TAO:0001559 xref: UMLS:C0037949 {source="ncithesaurus:Vertebral_Column"} xref: UMLS:C1519455 {source="ncithesaurus:Spinal_Cord_Column"} xref: VHOG:0001142 xref: VSAO:0000185 xref: Wikipedia:Vertebral_column xref: XAO:0003074 xref: ZFA:0001559 is_a: UBERON:0000075 ! subdivision of skeletal system intersection_of: UBERON:0000075 ! subdivision of skeletal system intersection_of: RO:0002473 UBERON:0010913 ! composed primarily of vertebral element relationship: BFO:0000050 UBERON:0011138 {source="cjm"} ! part of postcranial axial skeletal system relationship: protects UBERON:0002240 ! spinal cord relationship: RO:0002160 NCBITaxon:7742 ! only in taxon Vertebrata relationship: RO:0002473 UBERON:0010913 ! composed primarily of vertebral element [Term] id: UBERON:0001131 name: vertebral foramen namespace: uberon def: "A foramen within a vertebral element through which the spinal cord runs. It is formed by the anterior segment, and the posterior part, the vertebral arch." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Vertebral_foramen] synonym: "vertebra neural canal" EXACT [] xref: AAO:0000729 xref: EMAPA:37803 {source="MA:th"} xref: FMA:13479 xref: MA:0001454 xref: SCTID:280734009 xref: Wikipedia:Vertebral_foramen is_a: UBERON:0004111 ! anatomical conduit intersection_of: UBERON:0004111 ! anatomical conduit intersection_of: RO:0002570 UBERON:0002240 ! conduit for spinal cord intersection_of: RO:0002571 UBERON:0010913 ! lumen of vertebral element relationship: BFO:0000050 UBERON:0006692 ! part of vertebral canal relationship: RO:0002570 UBERON:0002240 ! conduit for spinal cord relationship: RO:0002571 UBERON:0010913 ! lumen of vertebral element property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/1/10/Foramenvertebrale.png" xsd:anyURI [Term] id: UBERON:0001133 name: cardiac muscle tissue namespace: uberon def: "Muscle tissue composed of cardiac muscle cells, forming the muscles of the heart[ZFA,modified]." [ZFA:0005280] synonym: "cardiac muscle" EXACT [] synonym: "cardiac muscle muscle tissue" EXACT [OBOL:automatic] synonym: "cardiac muscle textus muscularis" EXACT [OBOL:automatic] synonym: "heart muscle muscle tissue" EXACT [OBOL:automatic] synonym: "heart muscle textus muscularis" EXACT [OBOL:automatic] synonym: "heart myocardium muscle tissue" EXACT [OBOL:automatic] synonym: "heart myocardium textus muscularis" EXACT [OBOL:automatic] synonym: "muscle of heart muscle tissue" EXACT [OBOL:automatic] synonym: "muscle of heart textus muscularis" EXACT [OBOL:automatic] synonym: "muscle tissue of cardiac muscle" EXACT [OBOL:automatic] synonym: "muscle tissue of heart muscle" EXACT [OBOL:automatic] synonym: "muscle tissue of heart myocardium" EXACT [OBOL:automatic] synonym: "muscle tissue of muscle of heart" EXACT [OBOL:automatic] synonym: "muscle tissue of myocardium" EXACT [OBOL:automatic] synonym: "myocardium muscle tissue" EXACT [OBOL:automatic] synonym: "myocardium textus muscularis" EXACT [OBOL:automatic] synonym: "textus muscularis of cardiac muscle" EXACT [OBOL:automatic] synonym: "textus muscularis of heart muscle" EXACT [OBOL:automatic] synonym: "textus muscularis of heart myocardium" EXACT [OBOL:automatic] synonym: "textus muscularis of muscle of heart" EXACT [OBOL:automatic] synonym: "textus muscularis of myocardium" EXACT [OBOL:automatic] xref: AAO:0010245 xref: AEO:0000142 xref: BILA:0000134 xref: BTO:0000199 xref: CALOHA:TS-0440 xref: EHDAA2:0003142 xref: EMAPA:32688 xref: FMA:14068 xref: galen:CardiacMuscle xref: galen:CardiacMuscleTissue xref: ncithesaurus:Heart_Muscle xref: TAO:0005280 xref: Wikipedia:Cardiac_muscle xref: ZFA:0005280 is_a: UBERON:8600006 ! visceral striated muscle tissue intersection_of: UBERON:0002036 ! striated muscle tissue intersection_of: BFO:0000051 CL:0000746 ! has part cardiac muscle cell disjoint_from: UBERON:0001134 ! skeletal muscle tissue relationship: BFO:0000050 UBERON:0007100 ! part of primary circulatory organ relationship: RO:0002473 CL:0000746 ! composed primarily of cardiac muscle cell [Term] id: UBERON:0001134 name: skeletal muscle tissue namespace: uberon xref: EMAPA:32716 xref: FMA:14069 xref: MA:0002439 xref: NCIT:C13050 xref: SCTID:426215008 xref: UMLS:C0242692 {source="ncithesaurus:Skeletal_Muscle_Tissue"} xref: Wikipedia:Skeletal_striated_muscle is_a: UBERON:0002036 ! striated muscle tissue intersection_of: UBERON:0002385 ! muscle tissue intersection_of: RO:0002473 CL:0008002 ! composed primarily of skeletal muscle fiber relationship: BFO:0000050 UBERON:0014892 ! part of skeletal muscle organ, vertebrate relationship: RO:0002202 UBERON:0003082 ! develops from myotome relationship: RO:0002473 CL:0008002 ! composed primarily of skeletal muscle fiber property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/c/c0/Skeletal_muscle.jpg" xsd:anyURI property_value: x_1.1:contributor https://github.com/cmungall property_value: x_1.1:contributor https://github.com/dosumis property_value: x_1.1:contributor https://github.com/mellybelly property_value: x_1.1:contributor https://github.com/RDruzinsky [Term] id: UBERON:0001135 name: smooth muscle tissue namespace: uberon def: "Muscle tissue which is unstriated, composed primarily of smooth muscle fibers surrounded by a reticulum of collagen and elastic fibers. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length[GO]." [GO:0006939, Wikipedia:Smooth_muscle_tissue] synonym: "involuntary muscle" EXACT [] synonym: "non-striated muscle" EXACT [] synonym: "smooth muscle" EXACT [] xref: AAO:0010244 xref: AEO:0000141 xref: BTO:0001260 xref: CALOHA:TS-0943 xref: EFO:0000889 xref: EHDAA2:0003141 xref: EMAPA:32717 xref: EV:0100378 xref: FMA:14070 xref: GAID:167 xref: galen:SmoothMuscle xref: galen:SmoothMuscleTissue xref: MA:0000166 xref: MAT:0000303 xref: MESH:D009130 xref: MIAA:0000303 xref: NCIT:C12437 xref: TAO:0005274 xref: UMLS:C1267092 {source="ncithesaurus:Smooth_Muscle_Tissue"} xref: VHOG:0001246 xref: WBbt:0005781 xref: Wikipedia:Smooth_muscle_tissue xref: XAO:0000175 xref: ZFA:0005274 is_a: UBERON:0002385 ! muscle tissue intersection_of: UBERON:0002385 ! muscle tissue intersection_of: BFO:0000051 CL:0000192 ! has part smooth muscle cell disjoint_from: UBERON:0002036 ! striated muscle tissue relationship: BFO:0000051 GO:0071953 ! has part elastic fiber relationship: RO:0002473 CL:0000192 ! composed primarily of smooth muscle cell property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/3/3b/Glatte_Muskelzellen.jpg" xsd:anyURI [Term] id: UBERON:0001136 name: mesothelium namespace: uberon def: "Simple squamous epithelium of mesodermal origin which lines serous membranes. Examples: mesothelium of pleura, mesothelium of peritoneum[FMA]. Wikipedia: The mesothelium is a membrane that forms the lining of several body cavities: the pleura (thoracal cavity), peritoneum (abdominal cavity including the mesentery) and pericardium (heart sac). Mesothelial tissue also surrounds the male internal reproductive organs (the tunica vaginalis testis) and covers the internal reproductive organs of women (the tunica serosa uteri)." [FMA:14074, Wikipedia:Mesothelium] xref: AEO:0000111 xref: BTO:0002422 xref: CALOHA:TS-1183 xref: EHDAA2_RETIRED:0003111 xref: EHDAA:2331 xref: EHDAA:2349 xref: EHDAA:295 xref: EHDAA:6073 xref: EHDAA:640 xref: EHDAA:646 xref: EMAPA:32856 xref: FMA:14074 xref: MA:0000565 xref: NCIT:C33105 xref: SCTID:361918002 xref: UMLS:C0086610 {source="ncithesaurus:Mesothelium"} xref: Wikipedia:Mesothelium is_a: UBERON:0000487 ! simple squamous epithelium is_a: UBERON:0012275 ! meso-epithelium intersection_of: UBERON:0000487 ! simple squamous epithelium intersection_of: BFO:0000050 UBERON:0000042 ! part of serous membrane intersection_of: RO:0002202 UBERON:0000926 ! develops from mesoderm relationship: BFO:0000050 UBERON:0000042 ! part of serous membrane relationship: RO:0002473 CL:0000077 {source="FMA"} ! composed primarily of mesothelial cell property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/2/25/Mesothelium_peritoneal_wash_high_mag.jpg" xsd:anyURI [Term] id: UBERON:0001137 name: dorsum namespace: uberon def: "A major subdivision of an organism that is the entire part of the organism dorsal to a horizontal plane and bounded on one side by the same transverse plane. In vertebrares this includes the vertebral column.." [BSPO:0000063, UBERONREF:0000006, Wikipedia:Dorsum_(anatomy)] synonym: "back" EXACT [FMA:14181] synonym: "back of body proper" EXACT [FMA:14181] synonym: "dorsal part of organism" EXACT [] xref: BTO:0001713 xref: CALOHA:TS-2223 xref: EFO:0001405 xref: FMA:14181 xref: GAID:30 xref: galen:Back xref: MESH:D001415 xref: NCIT:C13062 xref: SCTID:123961009 xref: UMLS:C0004600 {source="ncithesaurus:Back"} xref: Wikipedia:Dorsum_(anatomy) is_a: UBERON:0000475 ! organism subdivision relationship: RO:0002160 NCBITaxon:33213 ! only in taxon Bilateria property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/e/ee/432px-Gray-back.PNG" xsd:anyURI [Term] id: UBERON:0001138 name: superior mesenteric vein namespace: uberon def: "In anatomy, the superior mesenteric vein (SMV) is a blood vessel that drains blood from the small intestine. At its termination behind the neck of the pancreas, the SMV combines with the splenic vein to form the hepatic portal vein. The SMV lies to the right of the similarly named artery, the superior mesenteric artery, which originates from the abdominal aorta. [WP,unvetted]." [Wikipedia:Superior_mesenteric_vein] xref: BTO:0002783 xref: EHDAA2:0001951 xref: EHDAA:5414 xref: EMAPA:18643 xref: FMA:14332 xref: MA:0002179 xref: NCIT:C33687 xref: SCTID:278031001 xref: UMLS:C0226742 {source="ncithesaurus:Superior_Mesenteric_Vein"} xref: VHOG:0000552 xref: Wikipedia:Superior_mesenteric_vein is_a: UBERON:0005617 ! mesenteric vein intersection_of: UBERON:0005617 ! mesenteric vein intersection_of: RO:0002179 UBERON:0002108 ! drains small intestine relationship: BFO:0000050 UBERON:0005806 ! part of portal system relationship: RO:0002170 UBERON:0001639 ! connected to hepatic portal vein relationship: RO:0002179 UBERON:0002108 ! drains small intestine relationship: RO:0002202 UBERON:0005487 {source="Wikipedia:Vitelline_vein"} ! develops from vitelline vein property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/3/33/Gray591.png" xsd:anyURI [Term] id: UBERON:0001139 name: common iliac vein namespace: uberon def: "A vein that drains the pelvis and lower limbs into the inferior vena cava." [MURDOCH:403, Wikipedia:Common_iliac_vein] synonym: "common iliac venous tree" EXACT [] xref: EMAPA:17874 xref: FMA:14333 xref: galen:CommonIliacVein xref: MA:0002143 xref: NCIT:C32359 xref: SCTID:181398004 xref: UMLS:C0226758 {source="ncithesaurus:Common_Iliac_Vein"} xref: Wikipedia:Common_iliac_vein is_a: UBERON:0005610 {source="MA"} ! iliac vein is_a: UBERON:0015212 ! lateral structure relationship: BSPO:0000126 UBERON:0001072 {source="FMA-abduced-lr"} ! in lateral side of posterior vena cava property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/6/65/Iliac_veins.gif" xsd:anyURI [Term] id: UBERON:0001140 name: renal vein namespace: uberon def: "Either of the pair of major vessels which arise from the renal hilus and return blood from the kidneys, suprarenal gland and the ureter to the inferior vena cava." [ISBN:0-683-40008-8, MGI:csmith, MP:0011323] synonym: "kidney vein" EXACT [OBOL:automatic] synonym: "renal venous tree" EXACT [] synonym: "vein of kidney" EXACT [OBOL:automatic] xref: BTO:0002681 xref: EHDAA2:0001602 xref: EHDAA:8722 xref: EMAPA:28376 xref: FMA:14334 xref: GAID:544 xref: galen:RenalVein xref: MA:0002210 xref: MESH:D012082 xref: NCIT:C33462 xref: SCTID:116358006 xref: UMLS:C0035092 {source="ncithesaurus:Renal_Vein"} xref: Wikipedia:Renal_vein is_a: UBERON:0001638 ! vein intersection_of: UBERON:0001638 ! vein intersection_of: RO:0002179 UBERON:0002113 ! drains kidney relationship: BFO:0000050 RO:0002577 ! part of system relationship: RO:0002179 UBERON:0002113 ! drains kidney relationship: RO:0002376 UBERON:0001072 ! tributary of posterior vena cava property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/7/76/Gray1122.png" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI [Term] id: UBERON:0001141 name: right renal vein namespace: uberon def: "A renal vein that drains the right kidney." [http://orcid.org/0000-0002-6601-2165] xref: EMAPA:37381 {source="MA:th"} xref: FMA:14335 xref: MA:0002212 xref: NCIT:C52695 xref: SCTID:116357001 xref: UMLS:C0508000 {source="ncithesaurus:Right_Renal_Vein"} is_a: UBERON:0001140 ! renal vein intersection_of: UBERON:0001140 ! renal vein intersection_of: RO:0002179 UBERON:0004539 ! drains right kidney relationship: RO:0002179 UBERON:0004539 ! drains right kidney property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI [Term] id: UBERON:0001142 name: left renal vein namespace: uberon def: "A renal vein that drains the left kidney." [http://orcid.org/0000-0002-6601-2165] xref: EMAPA:37166 {source="MA:th"} xref: FMA:14336 xref: MA:0002211 xref: NCIT:C52693 xref: SCTID:116356005 xref: UMLS:C0508001 {source="ncithesaurus:Left_Renal_Vein"} is_a: UBERON:0001140 ! renal vein intersection_of: UBERON:0001140 ! renal vein intersection_of: RO:0002179 UBERON:0004538 ! drains left kidney relationship: RO:0002179 UBERON:0004538 ! drains left kidney property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/7/76/Gray1122.png" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI [Term] id: UBERON:0001143 name: hepatic vein namespace: uberon def: "Vein that carries blood away from the liver[ZFA]." [https://sourceforge.net/tracker/?func=detail&aid=3565355&group_id=76834&atid=1205376, Wikipedia:Hepatic_vein, ZFA:0000670] synonym: "liver vein" EXACT [OBOL:automatic] synonym: "vein of liver" EXACT [OBOL:automatic] xref: AAO:0010216 xref: EMAPA:19221 xref: FMA:14337 xref: GAID:534 xref: galen:HepaticVein xref: MA:0003015 xref: MESH:D006503 xref: NCIT:C32736 xref: SCTID:278191001 xref: TAO:0000670 xref: UMLS:C0019155 {source="ncithesaurus:Hepatic_Vein"} xref: Wikipedia:Hepatic_vein xref: XAO:0000387 xref: ZFA:0000670 is_a: UBERON:0013126 ! vein of abdomen is_a: UBERON:0015796 ! liver blood vessel intersection_of: UBERON:0001638 ! vein intersection_of: RO:0002179 UBERON:0002107 ! drains liver disjoint_from: UBERON:0001639 ! hepatic portal vein relationship: BFO:0000050 RO:0002577 ! part of system relationship: BFO:0000050 UBERON:0006877 ! part of vasculature of liver relationship: RO:0002179 UBERON:0002107 ! drains liver relationship: RO:0002202 UBERON:0005487 {gci_filler="NCBITaxon:40674", gci_relation="BFO:0000050", source="Wikipedia:Vitelline_vein"} ! develops from vitelline vein relationship: RO:0002376 UBERON:0001072 {source="FMA-abduced-lr"} ! tributary of posterior vena cava property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/6/61/Gray1121.png" xsd:anyURI [Term] id: UBERON:0001144 name: testicular vein namespace: uberon def: "A vein that carries deoxygenated blood from a single male gonad. It is the male equivalent of the ovarian vein, and is the venous counterpart of the testicular artery. It is a paired vein, with one supplying each testis." [http://orcid.org/0000-0002-6601-2165, https://sourceforge.net/tracker/?func=detail&aid=3220553&group_id=76834&atid=1205376, Wikipedia:Testicular_vein] synonym: "male gonadal vein" EXACT [Wikipedia:Testicular_vein] synonym: "spermatic vein" EXACT [Wikipedia:Testicular_vein] synonym: "testicle vein" EXACT [OBOL:automatic] synonym: "testicular venous tree" EXACT [Wikipedia:Testicular_vein] synonym: "vein of testicle" EXACT [OBOL:automatic] xref: BTO:0002678 xref: EMAPA:18647 xref: FMA:14344 xref: MA:0002218 xref: MA:0002234 xref: NCIT:C53050 xref: SCTID:264496006 xref: UMLS:C0226718 {source="ncithesaurus:Spermatic_Vein"} xref: Wikipedia:Testicular_vein is_a: UBERON:0001638 ! vein is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0001638 ! vein intersection_of: RO:0002179 UBERON:0000473 ! drains testis relationship: BFO:0000050 RO:0002577 ! part of system relationship: BSPO:0000126 UBERON:0000468 ! in lateral side of multicellular organism relationship: RO:0002170 UBERON:0001072 ! connected to posterior vena cava relationship: RO:0002170 UBERON:0001330 ! connected to pampiniform plexus relationship: RO:0002179 UBERON:0000473 ! drains testis relationship: sexually_homologous_to UBERON:0001145 ! ovarian vein property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/1/1b/Gray590.png" xsd:anyURI [Term] id: UBERON:0001145 name: ovarian vein namespace: uberon def: "A vein that carries deoxygenated blood from its corresponding ovary to inferior vena cava or one of its tributaries." [Wikipedia:Ovarian_vein] synonym: "female reproductive system gonad vein" EXACT [OBOL:automatic] synonym: "female reproductive system gonada vein" EXACT [OBOL:automatic] synonym: "gonad of female reproductive system vein" EXACT [OBOL:automatic] synonym: "gonada of female reproductive system vein" EXACT [OBOL:automatic] synonym: "ovary vein" EXACT [OBOL:automatic] synonym: "vein of female reproductive system gonad" EXACT [OBOL:automatic] synonym: "vein of female reproductive system gonada" EXACT [OBOL:automatic] synonym: "vein of gonad of female reproductive system" EXACT [OBOL:automatic] synonym: "vein of gonada of female reproductive system" EXACT [OBOL:automatic] synonym: "vein of ovary" EXACT [OBOL:automatic] xref: EMAPA:18644 xref: FMA:14346 xref: MA:0002186 xref: NCIT:C53058 xref: SCTID:278193003 xref: UMLS:C0226720 {source="ncithesaurus:Ovarian_Vein"} xref: Wikipedia:Ovarian_vein is_a: UBERON:0001638 ! vein is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0001638 ! vein intersection_of: RO:0002179 UBERON:0000992 ! drains ovary relationship: BFO:0000050 RO:0002577 ! part of system relationship: BSPO:0000126 UBERON:0000468 ! in lateral side of multicellular organism relationship: RO:0002179 UBERON:0000992 ! drains ovary property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/c/cf/Ovarschaf.jpg" xsd:anyURI [Term] id: UBERON:0001152 name: cystic duct namespace: uberon def: "The tubular structure that conducts gall bladder contents from the gall bladder to the common bile duct." [ISBN:0-683-40008-8, MP:0009493] xref: EHDAA2:0000333 xref: EHDAA:3045 xref: EMAPA:16841 xref: FMA:14539 xref: GAID:290 xref: galen:CysticDuct xref: MA:0000355 xref: MESH:D003549 xref: NCIT:C32421 xref: SCTID:245398005 xref: TAO:0005166 xref: UMLS:C0010672 {source="ncithesaurus:Cystic_Duct"} xref: VHOG:0000213 xref: Wikipedia:Cystic_duct xref: ZFA:0005166 is_a: UBERON:0003703 {source="FMA"} ! extrahepatic bile duct intersection_of: UBERON:0000058 ! duct intersection_of: RO:0002150 UBERON:0001174 ! continuous with common bile duct intersection_of: RO:0002150 UBERON:0002110 ! continuous with gallbladder disjoint_from: UBERON:0005171 ! hepatic duct relationship: channels_into UBERON:0001174 ! common bile duct relationship: RO:0002150 UBERON:0001174 ! continuous with common bile duct relationship: RO:0002150 UBERON:0002110 ! continuous with gallbladder relationship: RO:0002202 UBERON:0005604 {source="EHDAA2"} ! develops from extrahepatic part of hepatic duct property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/4/48/Illu_liver_gallbladder.jpg" xsd:anyURI property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/5/5d/Digestive_system_showing_bile_duct.png" xsd:anyURI [Term] id: UBERON:0001155 name: colon namespace: uberon def: "A portion of the large intestine before it becomes the rectum. In mammals, the colon is the most part of the large intestine, excluding the vermiform appendix, the rectum and the anal canal." [http://orcid.org/0000-0002-2825-0621, http://orcid.org/0000-0002-6601-2165, Wikipedia:Colon_(anatomy), ZFIN:curator] synonym: "large bowel" EXACT [] xref: AAO:0010400 xref: BTO:0000269 xref: CALOHA:TS-0158 xref: EFO:0000361 xref: EMAPA:18939 xref: EV:0100079 xref: FMA:14543 xref: GAID:309 xref: galen:Colon xref: MA:0000335 xref: MAP:0000001 xref: MAT:0000526 xref: MESH:D003106 xref: NCIT:C12382 xref: SCTID:302508007 xref: TAO:0000706 xref: UMLS:C0009368 {source="ncithesaurus:Colon"} xref: VHOG:0000648 xref: Wikipedia:Colon_(anatomy) xref: XAO:0000243 xref: ZFA:0000706 is_a: UBERON:0004921 ! subdivision of digestive tract relationship: BFO:0000050 UBERON:0000059 {source="FMA"} ! part of large intestine relationship: RO:0002160 NCBITaxon:7742 ! only in taxon Vertebrata relationship: RO:0002433 UBERON:0000059 ! contributes to morphology of large intestine [Term] id: UBERON:0001159 name: sigmoid colon namespace: uberon def: "The part of the large intestine that is closest to the rectum and anus. It forms a loop that averages about 40 cm. in length, and normally lies within the pelvis, but on account of its freedom of movement it is liable to be displaced into the abdominal cavity." [Wikipedia:Sigmoid_colon] xref: BTO:0000645 xref: CALOHA:TS-2044 xref: EFO:0000846 xref: EMAPA:36391 xref: FMA:14548 xref: galen:SigmoidColon xref: MAT:0000314 xref: MESH:D012809 xref: MIAA:0000314 xref: NCIT:C12384 xref: NCIT:C33550 xref: SCTID:362166007 xref: UMLS:C0227391 {source="ncithesaurus:Sigmoid_Colon"} xref: UMLS:C0682612 {source="ncithesaurus:Sigmoid_Flexure"} xref: Wikipedia:Sigmoid_colon is_a: UBERON:0000168 {source="FMA"} ! proximal-distal subdivision of colon relationship: RO:0002150 UBERON:0001052 ! continuous with rectum relationship: RO:0002202 UBERON:0001046 {source="Wikipedia"} ! develops from hindgut property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/3/3b/Dickdarm-Schema.svg" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/SBU_F_Intestine_Large.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/SBU_M_Intestine_Large.glb" xsd:anyURI [Term] id: UBERON:0001161 name: body of stomach namespace: uberon def: "The body of stomach is the part of the stomach that lies between the fundus above and the pyloric antrum below; its boundaries are poorly defined[GO]." [GO:0014845, Wikipedia:Body_of_stomach] synonym: "corpus gastricum (ventriculare)" EXACT [] synonym: "gastric body" EXACT [] synonym: "stomach body" EXACT [] xref: BTO:0000505 xref: EMAPA:35810 xref: FMA:14560 xref: galen:GastricCorpus xref: MA:0002559 xref: NCIT:C12258 xref: SCTID:362140009 xref: UMLS:C0227230 {source="ncithesaurus:Body_of_Stomach"} xref: Wikipedia:Body_of_stomach is_a: UBERON:0009870 {source="FMA"} ! zone of stomach property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/3/31/Gray1046.svg" xsd:anyURI [Term] id: UBERON:0001165 name: pyloric antrum namespace: uberon def: "The area at the bottom of the stomach on the caudal side of the pyloric canal that contains gastrin-producing G cells, which stimulate acid production, and the luminal pH-sensitive population of somatostatin-producing D cells." [ISBN:0-683-40008-8, MP:0010790] synonym: "antrum of stomach" EXACT [] synonym: "stomach pyloric antrum" EXACT [] xref: BTO:0001732 xref: EFO:0002555 xref: EMAPA:17891 xref: FMA:14579 xref: GAID:332 xref: galen:PyloricAntrum xref: MA:0001624 xref: MESH:D011706 xref: NCIT:C12259 xref: SCTID:362142001 xref: UMLS:C0034193 {source="ncithesaurus:Antrum_Pylori"} xref: Wikipedia:Pyloric_antrum is_a: UBERON:0009870 {source="FMA"} ! zone of stomach relationship: BFO:0000050 UBERON:0001166 {source="Wikipedia"} ! part of pylorus relationship: BFO:0000051 CL:0000502 ! has part type D enteroendocrine cell relationship: BFO:0000051 CL:0000508 ! has part type G enteroendocrine cell relationship: RO:0002150 UBERON:0001161 ! continuous with body of stomach relationship: RO:0002433 UBERON:0001166 ! contributes to morphology of pylorus property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/3/31/Gray1046.svg" xsd:anyURI [Term] id: UBERON:0001166 name: pylorus namespace: uberon def: "The stomach tissue region surrounding and controlling the distal outlet of the stomach, which opens into the duodenum." [MGI:csmith, MP:0010785] synonym: "pyloric part of stomach" EXACT [] synonym: "pyloric region" EXACT [] synonym: "stomach pyloric region" EXACT [EHDAA2:0001580] xref: BTO:0001146 xref: EHDAA2:0001580 xref: EHDAA:4860 xref: EMAPA:17631 xref: FMA:14581 xref: GAID:333 xref: galen:Pylorus xref: MA:0002560 xref: MESH:D011708 xref: NCIT:C12260 xref: SCTID:362143006 xref: UMLS:C0034196 {source="ncithesaurus:Pylorus"} xref: VHOG:0000420 xref: Wikipedia:Pylorus is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0009870 ! zone of stomach intersection_of: UBERON:0009870 ! zone of stomach intersection_of: BFO:0000051 UBERON:0001165 ! has part pyloric antrum intersection_of: BFO:0000051 UBERON:0008858 ! has part pyloric canal intersection_of: BFO:0000051 UBERON:0008861 ! has part pyloric gastric gland relationship: BFO:0000051 UBERON:0001165 ! has part pyloric antrum relationship: BFO:0000051 UBERON:0008858 ! has part pyloric canal relationship: BFO:0000051 UBERON:0008861 ! has part pyloric gastric gland relationship: RO:0002433 UBERON:0000945 ! contributes to morphology of stomach property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/3/31/Gray1046.svg" xsd:anyURI [Term] id: UBERON:0001167 name: wall of stomach namespace: uberon def: "The layered structure that makes up the stomach, typiclly consists of a serous coat, a muscular coat, a mucous membrane, and other tissue layers in between." [MGI:csmith, MP:0010783] synonym: "anatomical wall of stomach" EXACT [OBOL:automatic] synonym: "anatomical wall of ventriculus" EXACT [OBOL:automatic] synonym: "gastric wall" EXACT [] synonym: "stomach anatomical wall" EXACT [OBOL:automatic] synonym: "stomach wall" EXACT [] synonym: "ventriculus anatomical wall" EXACT [OBOL:automatic] synonym: "ventriculus wall" EXACT [OBOL:automatic] synonym: "wall of ventriculus" EXACT [OBOL:automatic] xref: EMAPA:35826 xref: FMA:14582 xref: galen:WallOfStomach xref: MA:0002692 xref: SCTID:279995000 is_a: UBERON:0000328 ! gut wall intersection_of: UBERON:0000060 ! anatomical wall intersection_of: BFO:0000050 UBERON:0000945 ! part of stomach relationship: BFO:0000050 UBERON:0000945 ! part of stomach relationship: RO:0002433 UBERON:0000945 ! contributes to morphology of stomach [Term] id: UBERON:0001168 name: wall of small intestine namespace: uberon def: "An anatomical wall that is part of a small intestine [Automatically generated definition]." [OBOL:automatic] synonym: "anatomical wall of small bowel" EXACT [OBOL:automatic] synonym: "anatomical wall of small intestine" EXACT [OBOL:automatic] synonym: "small bowel anatomical wall" EXACT [OBOL:automatic] synonym: "small bowel wall" EXACT [OBOL:automatic] synonym: "small intestinal wall" EXACT [] synonym: "small intestine anatomical wall" EXACT [OBOL:automatic] synonym: "small intestine wall" EXACT [] synonym: "wall of small bowel" EXACT [OBOL:automatic] xref: EMAPA:35785 xref: FMA:14615 xref: MA:0002696 xref: NCIT:C33573 xref: UMLS:C1519375 {source="ncithesaurus:Small_Intestinal_Wall_Tissue"} is_a: UBERON:0001262 ! wall of intestine intersection_of: UBERON:0000060 ! anatomical wall intersection_of: BFO:0000050 UBERON:0002108 ! part of small intestine relationship: BFO:0000050 UBERON:0002108 ! part of small intestine [Term] id: UBERON:0001169 name: wall of large intestine namespace: uberon def: "An anatomical wall that is part of a large intestine [Automatically generated definition]." [OBOL:automatic] synonym: "anatomical wall of large intestine" EXACT [OBOL:automatic] synonym: "large intestinal wall" EXACT [] synonym: "large intestine anatomical wall" EXACT [OBOL:automatic] synonym: "large intestine wall" EXACT [] xref: EMAPA:35470 xref: FMA:14619 xref: MA:0002695 is_a: UBERON:0001262 ! wall of intestine intersection_of: UBERON:0000060 ! anatomical wall intersection_of: BFO:0000050 UBERON:0000059 ! part of large intestine relationship: BFO:0000050 UBERON:0000059 ! part of large intestine [Term] id: UBERON:0001170 name: mesentery of small intestine namespace: uberon def: "The peritoneum responsible for connecting the jejunum and ileum (parts of the small intestine) to the back wall of the abdomen. Between the two sheets of peritoneum are blood vessels, lymph vessels, and nerves. This allows these parts of the small intestine to move relatively freely within the abdominopelvic cavity. The brain, however, cannot map sensation accurately, so sensation is usually referred to the midline, an example of referred pain[WP]." [Wikipedia:Mesentery#Mesentery_.28proper.29] synonym: "mesentery (proper)" EXACT [Wikipedia:Mesentery] synonym: "mesentery proper" EXACT [FMA:14643] synonym: "small intestinal mesentery" EXACT [FMA:14643] synonym: "small intestine mesentery" EXACT [OBOL:automatic] xref: EMAPA:37745 {source="MA:th"} xref: FMA:14643 xref: MA:0001555 xref: SCTID:245456008 xref: Wikipedia:Mesentery#Mesentery_.28proper.29 is_a: UBERON:0001206 ! serosa of small intestine is_a: UBERON:0004854 ! gastrointestinal system mesentery is_a: UBERON:0007826 {source="FMA"} ! peritoneal mesentery intersection_of: UBERON:0002095 ! mesentery intersection_of: BFO:0000050 UBERON:0002108 ! part of small intestine [Term] id: UBERON:0001171 name: portal lobule namespace: uberon def: "The triangular region on the periphery of the liver lobules that contain a bile duct and a terminal branch of the hepatic artery and portal vein, and may also include a lymphatic vessel." [MP:0008992] xref: FMA:14653 xref: MA:0002498 xref: NCIT:C33341 xref: UMLS:C0682620 {source="ncithesaurus:Portal_Lobule"} is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0009911 {source="FMA"} ! lobule relationship: BFO:0000050 UBERON:0001280 {source="MA", source="MP"} ! part of liver parenchyma relationship: RO:0002433 UBERON:0001280 ! contributes to morphology of liver parenchyma [Term] id: UBERON:0001172 name: hepatic acinus namespace: uberon def: "The functional unit of the liver, consisting of a mass of hepatocytes from adjacent liver lobules aligned around the hepatic arterioles and portal venules just as they anastomose into sinusoids." [http://orcid.org/0000-0002-6601-2165, http://www.vivo.colostate.edu/hbooks/pathphys/digestion/liver/histo_acinus.html] synonym: "liver acinus" EXACT [] synonym: "portal acinus" EXACT [] xref: EMAPA:35497 xref: FMA:14654 xref: MA:0002496 xref: NCIT:C32992 xref: SCTID:272214009 xref: UMLS:C0227519 {source="ncithesaurus:Liver_Acinus"} is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0011858 ! acinus of exocrine gland relationship: BFO:0000050 UBERON:0001280 {source="cjm"} ! part of liver parenchyma relationship: RO:0002131 UBERON:0001171 ! overlaps portal lobule relationship: RO:0002131 UBERON:0004647 ! overlaps liver lobule [Term] id: UBERON:0001173 name: biliary tree namespace: uberon def: "A complex network of conduits that begins with the canals of Hering (intralobar bile duct) and progressively merges into a system of interlobular, septal, and major ducts which then coalesce to form the extrahepatic bile ducts, which finally deliver bile to the intestine, and in some species to the gallbladder." [DOI:10.1002/ar.20664] xref: AAO:0011020 xref: EMAPA:35172 xref: FMA:14665 xref: SCTID:181267003 xref: UMLS:C0005423 {source="ncithesaurus:Biliary_Tract"} xref: Wikipedia:Biliary_tract xref: XAO:0000455 is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0013765 ! digestive system element intersection_of: UBERON:0000062 ! organ intersection_of: BFO:0000050 UBERON:0002294 ! part of biliary system intersection_of: RO:0002473 UBERON:0002394 ! composed primarily of bile duct relationship: BFO:0000050 UBERON:0002294 ! part of biliary system relationship: BFO:0000051 UBERON:0001246 ! has part interlobular bile duct relationship: BFO:0000051 UBERON:0001282 ! has part intralobular bile duct relationship: BFO:0000051 UBERON:0003703 ! has part extrahepatic bile duct relationship: RO:0002202 UBERON:0004912 ! develops from biliary bud relationship: RO:0002433 UBERON:0002423 ! contributes to morphology of hepatobiliary system relationship: RO:0002473 UBERON:0002394 ! composed primarily of bile duct [Term] id: UBERON:0001174 name: common bile duct namespace: uberon def: "The part of the biliary tree formed by the union of the cystic duct and the common hepatic duct." [MGI:csmith, MP:0009495] synonym: "ductus choledochus (biliaris)" EXACT [] xref: EHDAA2:0000303 xref: EHDAA:3981 xref: EMAPA:17201 xref: FMA:14667 xref: GAID:282 xref: galen:CommonBileDuct xref: MA:0001631 xref: MESH:D003135 xref: NCIT:C12698 xref: SCTID:362199009 xref: TAO:0005165 xref: UMLS:C0009437 {source="ncithesaurus:Common_Bile_Duct"} xref: VHOG:0000214 xref: Wikipedia:Common_bile_duct xref: ZFA:0005165 is_a: UBERON:0003703 ! extrahepatic bile duct relationship: channels_into UBERON:0001064 ! ventral pancreatic duct relationship: RO:0002150 UBERON:0001152 ! continuous with cystic duct relationship: RO:0002150 UBERON:0001175 ! continuous with common hepatic duct property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/5/5d/Digestive_system_showing_bile_duct.png" xsd:anyURI [Term] id: UBERON:0001175 name: common hepatic duct namespace: uberon def: "Predominantly extrahepatic bile duct which is formed by the junction of the right and left hepatic ducts, which are predominantly intrahepatic, and, in turn, joins the cystic duct to form the common bile duct[GAID]. The common hepatic duct is the duct formed by the convergence of the right hepatic duct (which drains bile from the right functional lobe of the liver) and the left hepatic duct (which drains bile from the left functional lobe of the liver). The common hepatic duct then joins the cystic duct coming from the gallbladder to form the common bile duct[WP]." [Wikipedia:Common_hepatic_duct, ZFIN:curator] xref: EMAPA:19101 xref: FMA:14668 xref: GAID:286 xref: MA:0002660 xref: MESH:D006500 xref: NCIT:C32356 xref: SCTID:245403006 xref: UMLS:C0019149 {source="ncithesaurus:Common_Hepatic_Duct"} xref: VHOG:0000220 xref: Wikipedia:Common_hepatic_duct is_a: UBERON:0003703 {source="FMA"} ! extrahepatic bile duct relationship: BFO:0000050 UBERON:0005604 {source="MA"} ! part of extrahepatic part of hepatic duct relationship: channels_into UBERON:0001174 ! common bile duct relationship: RO:0002150 UBERON:0001176 {source="Wikipedia"} ! continuous with right hepatic duct relationship: RO:0002150 UBERON:0001177 {source="Wikipedia"} ! continuous with left hepatic duct relationship: RO:0002495 UBERON:0010081 ! immediate transformation of future common hepatic duct property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/4/48/Illu_liver_gallbladder.jpg" xsd:anyURI [Term] id: UBERON:0001176 name: right hepatic duct namespace: uberon def: "The duct that drains bile from the right half of the liver and joins the left hepatic duct to form the common hepatic duct." [http://www.medterms.com/script/main/art.asp?articlekey=26034] xref: EHDAA2:0001727 xref: EHDAA:3992 xref: EMAPA:32797 xref: FMA:14669 xref: MA:0001639 xref: NCIT:C33476 xref: SCTID:245401008 xref: UMLS:C0227557 {source="ncithesaurus:Right_Hepatic_Duct"} xref: VHOG:0000217 is_a: UBERON:0003703 ! extrahepatic bile duct intersection_of: UBERON:0003703 ! extrahepatic bile duct intersection_of: RO:0002150 UBERON:0001114 ! continuous with right lobe of liver relationship: BFO:0000050 UBERON:0005171 ! part of hepatic duct relationship: RO:0002150 UBERON:0001114 ! continuous with right lobe of liver [Term] id: UBERON:0001177 name: left hepatic duct namespace: uberon def: "The duct that drains bile from the left half of the liver and joins the right hepatic duct to form the common hepatic duct." [http://www.medterms.com/script/main/art.asp?articlekey=26035] xref: EHDAA2:0000941 xref: EHDAA:3990 xref: EMAPA:32795 xref: FMA:14670 xref: MA:0001638 xref: NCIT:C32960 xref: SCTID:245400009 xref: UMLS:C0227560 {source="ncithesaurus:Left_Hepatic_Duct"} xref: VHOG:0000218 is_a: UBERON:0003703 ! extrahepatic bile duct intersection_of: UBERON:0003703 ! extrahepatic bile duct intersection_of: RO:0002150 UBERON:0001115 ! continuous with left lobe of liver relationship: BFO:0000050 UBERON:0005171 ! part of hepatic duct relationship: RO:0002150 UBERON:0001115 ! continuous with left lobe of liver [Term] id: UBERON:0001178 name: visceral peritoneum namespace: uberon def: "The inner layer of peritoneum that is wrapped around organs located inside the intraperitoneal space." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Peritoneum#Types] synonym: "visceral serous membrane of peritoneum" EXACT [UBERON:cjm] xref: EMAPA:16592 xref: FMA:14703 xref: SCTID:362702003 xref: TAO:0005132 xref: VHOG:0001528 xref: Wikipedia:Visceral_peritoneum xref: ZFA:0005132 is_a: UBERON:0022350 ! visceral serous membrane intersection_of: UBERON:0022350 ! visceral serous membrane intersection_of: BFO:0000050 UBERON:0002358 ! part of peritoneum relationship: BFO:0000050 UBERON:0002358 ! part of peritoneum property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray1040.png" xsd:anyURI [Term] id: UBERON:0001179 name: peritoneal cavity namespace: uberon def: "Anatomical cavity bounded by visceral and parietal peritoneum." [http://orcid.org/0000-0002-6601-2165, https://github.com/obophenotype/uberon/issues/86, Wikipedia:Peritoneal_cavity] xref: BTO:0001782 xref: EHDAA2:0001446 xref: EMAPA:16138 xref: FMA:14704 xref: GAID:24 xref: MA:0000054 xref: MESH:D010529 xref: NCIT:C12769 xref: SCTID:181616008 xref: UMLS:C1704247 {source="ncithesaurus:Peritoneal_Cavity"} xref: VHOG:0000852 xref: Wikipedia:Peritoneal_cavity is_a: UBERON:0035809 ! serous cavity intersection_of: UBERON:0002553 ! anatomical cavity intersection_of: RO:0002220 UBERON:0001178 ! adjacent to visceral peritoneum intersection_of: RO:0002220 UBERON:0001366 ! adjacent to parietal peritoneum intersection_of: RO:0002572 UBERON:0035820 ! luminal space of peritoneal sac relationship: RO:0002202 UBERON:0003887 {source="Wikipedia"} ! develops from intraembryonic coelom relationship: RO:0002220 UBERON:0001178 ! adjacent to visceral peritoneum relationship: RO:0002220 UBERON:0001366 ! adjacent to parietal peritoneum relationship: RO:0002572 UBERON:0035820 ! luminal space of peritoneal sac [Term] id: UBERON:0001184 name: renal artery namespace: uberon def: "One of two laterally paired arteries that supplies the kidneys. These are large arteries that branch from the dorsal aorta in primitive vertebrates." [ISBN:0073040584, Wikipedia:Renal_artery] synonym: "renal arterial tree" EXACT [] xref: AAO:0010223 xref: BTO:0001165 xref: EFO:0002552 xref: EHDAA2:0004100 xref: EHDAA:5321 xref: EHDAA:8594 xref: EMAPA:28373 xref: FMA:14751 xref: GAID:507 xref: galen:RenalArtery xref: MA:0002035 xref: MESH:D012077 xref: NCIT:C12778 xref: RETIRED_EHDAA2:0001600 xref: SCTID:181339005 xref: TAO:0000420 xref: UMLS:C0035065 {source="ncithesaurus:Renal_Artery"} xref: Wikipedia:Renal_artery xref: ZFA:0000420 is_a: UBERON:0012254 ! abdominal aorta artery intersection_of: UBERON:0001637 ! artery intersection_of: RO:0002178 UBERON:0002113 ! supplies kidney relationship: RO:0002178 UBERON:0002113 ! supplies kidney property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/d/da/Gray1120.png" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI [Term] id: UBERON:0001185 name: right renal artery namespace: uberon def: "Renal artery that supplies the right kidney." [https://orcid.org/0000-0002-6601-2165] synonym: "right renal arterial tree" EXACT [] xref: EMAPA:37380 {source="MA:th"} xref: FMA:14752 xref: MA:0002037 xref: NCIT:C52740 xref: SCTID:36800007 xref: UMLS:C0226332 {source="ncithesaurus:Right_Renal_Artery"} is_a: UBERON:0001184 ! renal artery intersection_of: UBERON:0001184 ! renal artery intersection_of: RO:0002178 UBERON:0004539 ! supplies right kidney relationship: RO:0002178 UBERON:0004539 ! supplies right kidney property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/d/da/Gray1120.png" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI [Term] id: UBERON:0001186 name: left renal artery namespace: uberon def: "Renal artery that supplies the left kidney." [https://orcid.org/0000-0002-6601-2165] synonym: "left renal arterial tree" EXACT [] xref: EMAPA:37098 {source="MA:th"} xref: FMA:14753 xref: MA:0002036 xref: NCIT:C52741 xref: SCTID:19215005 xref: UMLS:C0226333 {source="ncithesaurus:Left_Renal_Artery"} is_a: UBERON:0001184 ! renal artery intersection_of: UBERON:0001184 ! renal artery intersection_of: RO:0002178 UBERON:0004538 ! supplies left kidney relationship: RO:0002178 UBERON:0004538 ! supplies left kidney property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI [Term] id: UBERON:0001187 name: testicular artery namespace: uberon def: "One of a pair of arteries that is a branch of the abdominal aorta that supplies blood to a male gonad." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Testicular_artery] synonym: "testicular arterial tree" EXACT [] xref: EMAPA:18621 xref: FMA:14758 xref: MA:0002063 xref: SCTID:244281003 xref: Wikipedia:Testicular_artery is_a: UBERON:0010192 ! genital artery intersection_of: UBERON:0001637 ! artery intersection_of: RO:0002178 UBERON:0000473 ! supplies testis relationship: RO:0002178 UBERON:0000473 ! supplies testis property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/a/af/Gray531.png" xsd:anyURI [Term] id: UBERON:0001188 name: right testicular artery namespace: uberon def: "A testicular artery that supplies a right testicle." [OBOL:automatic] synonym: "right spermatic artery" EXACT [] synonym: "trunk of right testicular arterial tree" EXACT [] xref: EMAPA:37382 {source="MA:th"} xref: FMA:14759 xref: MA:0002042 xref: NCIT:C52738 xref: UMLS:C0734076 {source="ncithesaurus:Right_Spermatic_Artery"} is_a: UBERON:0001187 ! testicular artery is_a: UBERON:0003468 ! ureteric segment of renal artery intersection_of: UBERON:0001187 ! testicular artery intersection_of: RO:0002178 UBERON:0004534 ! supplies right testis relationship: RO:0002178 UBERON:0001222 ! supplies right ureter relationship: RO:0002178 UBERON:0004534 ! supplies right testis [Term] id: UBERON:0001189 name: left testicular artery namespace: uberon def: "A testicular artery that supplies a left testicle." [OBOL:automatic] synonym: "left spermatic artery" EXACT [] synonym: "trunk of left testicular arterial tree" EXACT [] xref: EMAPA:37099 {source="MA:th"} xref: FMA:14760 xref: MA:0002041 xref: NCIT:C52739 xref: UMLS:C0734077 {source="ncithesaurus:Left_Spermatic_Artery"} is_a: UBERON:0001187 ! testicular artery is_a: UBERON:0003468 ! ureteric segment of renal artery intersection_of: UBERON:0001187 ! testicular artery intersection_of: RO:0002178 UBERON:0004533 ! supplies left testis relationship: RO:0002178 UBERON:0001223 ! supplies left ureter relationship: RO:0002178 UBERON:0004533 ! supplies left testis [Term] id: UBERON:0001190 name: ovarian artery namespace: uberon def: "An artery that supplies an ovary." [OBOL:automatic] synonym: "ovarian arterial tree" EXACT [] xref: EMAPA:18620 xref: FMA:14761 xref: MA:0002012 xref: NCIT:C33242 xref: SCTID:244280002 xref: UMLS:C0226411 {source="ncithesaurus:Ovarian_Artery"} xref: Wikipedia:Ovarian_artery is_a: UBERON:0001637 ! artery intersection_of: UBERON:0001637 ! artery intersection_of: RO:0002178 UBERON:0000992 ! supplies ovary relationship: BFO:0000050 RO:0002577 ! part of system relationship: RO:0002170 UBERON:0001516 ! connected to abdominal aorta relationship: RO:0002178 UBERON:0000992 ! supplies ovary property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/a/ae/Gray1170.png" xsd:anyURI [Term] id: UBERON:0001193 name: hepatic artery namespace: uberon def: "An artery that supplies the liver." [https://orcid.org/0000-0002-6601-2165, Wikipedia:Hepatic_artery_proper] xref: BTO:0004307 xref: EMAPA:17859 xref: FMA:14769 xref: GAID:496 xref: galen:HepaticArtery xref: MA:0001963 xref: MESH:D006499 xref: NCIT:C32729 xref: SCTID:76015000 xref: TAO:0005161 xref: UMLS:C0019145 {source="ncithesaurus:Hepatic_Artery"} xref: ZFA:0005161 is_a: UBERON:0001637 ! artery intersection_of: UBERON:0001637 ! artery intersection_of: RO:0002178 UBERON:0002107 ! supplies liver relationship: BFO:0000050 RO:0002577 ! part of system relationship: RO:0002178 UBERON:0002107 ! supplies liver property_value: IAO:0000232 "currently defined in a generic fashion." xsd:string property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/4/4c/Common_and_proper_hepatic_artery.png" xsd:anyURI [Term] id: UBERON:0001194 name: splenic artery namespace: uberon def: "An artery that supplies the spleen." [http://orcid.org/0000-0002-6601-2165] synonym: "lienal artery" EXACT [MA:0001991] xref: EMAPA:19216 xref: FMA:14773 xref: GAID:510 xref: galen:SplenicArtery xref: MA:0001991 xref: MA:0003177 xref: MESH:D013157 xref: NCIT:C33597 xref: SCTID:244266009 xref: UMLS:C0037996 {source="ncithesaurus:Splenic_Artery"} xref: Wikipedia:Splenic_artery is_a: UBERON:0001637 ! artery intersection_of: UBERON:0001637 ! artery intersection_of: RO:0002178 UBERON:0002106 ! supplies spleen disjoint_from: UBERON:0001640 ! celiac artery relationship: BFO:0000050 RO:0002577 ! part of system relationship: RO:0002178 UBERON:0002106 ! supplies spleen relationship: RO:0002252 UBERON:0001640 ! connecting branch of celiac artery property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/a/a2/Gray1188.png" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI [Term] id: UBERON:0001199 name: mucosa of stomach namespace: uberon def: "The mucosal layer that lines the stomach." [http://orcid.org/0000-0002-6601-2165] synonym: "gastric mucosa" EXACT [] synonym: "gastric mucous membrane" EXACT [] synonym: "mucosa of organ of stomach" EXACT [OBOL:automatic] synonym: "mucosa of organ of ventriculus" EXACT [OBOL:automatic] synonym: "mucosa of ventriculus" EXACT [OBOL:automatic] synonym: "mucous membrane of stomach" EXACT [] synonym: "mucous membrane of ventriculus" EXACT [OBOL:automatic] synonym: "organ mucosa of stomach" EXACT [OBOL:automatic] synonym: "organ mucosa of ventriculus" EXACT [OBOL:automatic] synonym: "stomach mucosa" EXACT [] synonym: "stomach mucosa of organ" EXACT [OBOL:automatic] synonym: "stomach mucous membrane" EXACT [OBOL:automatic] synonym: "stomach organ mucosa" EXACT [OBOL:automatic] synonym: "tunica mucosa (gaster)" EXACT [] synonym: "ventriculus mucosa" EXACT [OBOL:automatic] synonym: "ventriculus mucosa of organ" EXACT [OBOL:automatic] synonym: "ventriculus mucous membrane" EXACT [OBOL:automatic] synonym: "ventriculus organ mucosa" EXACT [OBOL:automatic] xref: BTO:0001308 xref: CALOHA:TS-0404 xref: EMAPA:35817 xref: FMA:14907 xref: GAID:321 xref: galen:GastricMucosa xref: MA:0002683 xref: MESH:D005753 xref: NCIT:C32656 xref: SCTID:362131005 xref: UMLS:C0017136 {source="ncithesaurus:Gastric_Mucosa"} xref: Wikipedia:Gastric_mucosa is_a: UBERON:0004786 ! gastrointestinal system mucosa intersection_of: UBERON:0000344 ! mucosa intersection_of: BFO:0000050 UBERON:0000945 ! part of stomach relationship: BFO:0000050 UBERON:0001167 ! part of wall of stomach relationship: RO:0002215 GO:0001696 ! capable of gastric acid secretion relationship: RO:0002433 UBERON:0001167 ! contributes to morphology of wall of stomach property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/1/1c/Normal_gastric_mucosa_intermed_mag.jpg" xsd:anyURI [Term] id: UBERON:0001200 name: submucosa of stomach namespace: uberon def: "The fibrous connective tissue layer beneath the stomach mucosa." [MGI:csmith, MP:0010794] synonym: "gastric submucosa" EXACT [] synonym: "stomach submucosa" EXACT [] synonym: "submucosa of ventriculus" EXACT [OBOL:automatic] synonym: "tela submucosa (gaster)" EXACT [] synonym: "ventriculus submucosa" EXACT [OBOL:automatic] xref: BTO:0002110 xref: EMAPA:35825 xref: FMA:14908 xref: MA:0002685 xref: NCIT:C32663 xref: SCTID:52459002 xref: UMLS:C0227211 {source="ncithesaurus:Gastric_Submucosa"} is_a: UBERON:0018257 ! submucosa of digestive tract intersection_of: UBERON:0000009 ! submucosa intersection_of: BFO:0000050 UBERON:0000945 ! part of stomach relationship: BFO:0000050 UBERON:0001167 ! part of wall of stomach relationship: RO:0002433 UBERON:0001167 ! contributes to morphology of wall of stomach [Term] id: UBERON:0001201 name: serosa of stomach namespace: uberon def: "The outermost layer of the stomach wall, consisting of layers of connective tissue continuous with the peritoneum." [MGI:csmith, MP:0010793] synonym: "anatomical wall of stomach serosa" EXACT [OBOL:automatic] synonym: "anatomical wall of stomach serous membrane" EXACT [OBOL:automatic] synonym: "anatomical wall of ventriculus serosa" EXACT [OBOL:automatic] synonym: "anatomical wall of ventriculus serous membrane" EXACT [OBOL:automatic] synonym: "gastric wall serosa" EXACT [OBOL:automatic] synonym: "gastric wall serous membrane" EXACT [OBOL:automatic] synonym: "serosa of anatomical wall of stomach" EXACT [OBOL:automatic] synonym: "serosa of anatomical wall of ventriculus" EXACT [OBOL:automatic] synonym: "serosa of gastric wall" EXACT [OBOL:automatic] synonym: "serosa of stomach anatomical wall" EXACT [OBOL:automatic] synonym: "serosa of stomach wall" EXACT [OBOL:automatic] synonym: "serosa of ventriculus anatomical wall" EXACT [OBOL:automatic] synonym: "serosa of ventriculus wall" EXACT [OBOL:automatic] synonym: "serosa of wall of stomach" EXACT [OBOL:automatic] synonym: "serosa of wall of ventriculus" EXACT [OBOL:automatic] synonym: "serous coat of stomach" EXACT [] synonym: "serous membrane of anatomical wall of stomach" EXACT [OBOL:automatic] synonym: "serous membrane of anatomical wall of ventriculus" EXACT [OBOL:automatic] synonym: "serous membrane of gastric wall" EXACT [OBOL:automatic] synonym: "serous membrane of stomach anatomical wall" EXACT [OBOL:automatic] synonym: "serous membrane of stomach wall" EXACT [OBOL:automatic] synonym: "serous membrane of ventriculus anatomical wall" EXACT [OBOL:automatic] synonym: "serous membrane of ventriculus wall" EXACT [OBOL:automatic] synonym: "serous membrane of wall of stomach" EXACT [OBOL:automatic] synonym: "serous membrane of wall of ventriculus" EXACT [OBOL:automatic] synonym: "stomach anatomical wall serosa" EXACT [OBOL:automatic] synonym: "stomach anatomical wall serous membrane" EXACT [OBOL:automatic] synonym: "stomach serosa" EXACT [] synonym: "stomach wall serosa" EXACT [OBOL:automatic] synonym: "stomach wall serous membrane" EXACT [OBOL:automatic] synonym: "tunica serosa (gaster)" EXACT [] synonym: "ventriculus anatomical wall serosa" EXACT [OBOL:automatic] synonym: "ventriculus anatomical wall serous membrane" EXACT [OBOL:automatic] synonym: "ventriculus wall serosa" EXACT [OBOL:automatic] synonym: "ventriculus wall serous membrane" EXACT [OBOL:automatic] synonym: "visceral peritoneum of stomach" EXACT [] synonym: "wall of stomach serosa" EXACT [OBOL:automatic] synonym: "wall of stomach serous membrane" EXACT [OBOL:automatic] synonym: "wall of ventriculus serosa" EXACT [OBOL:automatic] synonym: "wall of ventriculus serous membrane" EXACT [OBOL:automatic] xref: EMAPA:35822 xref: FMA:14914 xref: MA:0001626 xref: NCIT:C32662 xref: SCTID:1353004 xref: UMLS:C1517453 {source="ncithesaurus:Gastric_Serosal_Surface"} is_a: UBERON:0004782 ! gastrointestinal system serosa intersection_of: UBERON:0000042 ! serous membrane intersection_of: BFO:0000050 UBERON:0001167 ! part of wall of stomach relationship: BFO:0000050 UBERON:0001167 ! part of wall of stomach relationship: RO:0002433 UBERON:0001167 ! contributes to morphology of wall of stomach [Term] id: UBERON:0001202 name: pyloric sphincter namespace: uberon def: "A strong ring of smooth muscle at the end of the pyloric canal which lets food pass from the stomach to the duodenum. It receives sympathetic innervation from the celiac ganglion[WP]." [https://orcid.org/0000-0002-6601-2165] synonym: "pyloric valve" EXACT [Wikipedia:Pylorus] xref: AAO:0011093 xref: EMAPA:19251 xref: FMA:14916 xref: MA:0002952 xref: NCIT:C33433 xref: SCTID:268073008 xref: UMLS:C0227238 {source="ncithesaurus:Pyloric_Sphincter"} xref: VHOG:0001466 xref: XAO:0000457 is_a: UBERON:0011185 ! gastrointestinal sphincter intersection_of: UBERON:0004590 ! sphincter muscle intersection_of: BFO:0000050 UBERON:0001166 ! part of pylorus relationship: BFO:0000050 UBERON:0001166 ! part of pylorus relationship: RO:0002150 UBERON:0008858 ! continuous with pyloric canal relationship: RO:0002220 UBERON:0002114 ! adjacent to duodenum relationship: RO:0002433 UBERON:0001166 ! contributes to morphology of pylorus [Term] id: UBERON:0001204 name: mucosa of small intestine namespace: uberon def: "A mucosa that is part of a small intestine [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of organ of small bowel" EXACT [OBOL:automatic] synonym: "mucosa of organ of small intestine" EXACT [OBOL:automatic] synonym: "mucosa of small bowel" EXACT [OBOL:automatic] synonym: "mucous membrane of small bowel" EXACT [OBOL:automatic] synonym: "mucous membrane of small intestine" EXACT [] synonym: "organ mucosa of small bowel" EXACT [OBOL:automatic] synonym: "organ mucosa of small intestine" EXACT [OBOL:automatic] synonym: "small bowel mucosa" EXACT [OBOL:automatic] synonym: "small bowel mucosa of organ" EXACT [OBOL:automatic] synonym: "small bowel mucous membrane" EXACT [OBOL:automatic] synonym: "small bowel organ mucosa" EXACT [OBOL:automatic] synonym: "small intestinal mucosa" EXACT [] synonym: "small intestine mucosa" EXACT [] synonym: "small intestine mucosa of organ" EXACT [OBOL:automatic] synonym: "small intestine mucous membrane" EXACT [] synonym: "small intestine organ mucosa" EXACT [OBOL:automatic] synonym: "tunica mucosa (intestinum tenue)" EXACT [] xref: BTO:0001259 xref: CALOHA:TS-0941 xref: EMAPA:35780 xref: FMA:14933 xref: MA:0002686 xref: NCIT:C33568 xref: SCTID:362144000 xref: UMLS:C0227261 {source="ncithesaurus:Small_Intestinal_Mucosa"} is_a: UBERON:0001242 ! intestinal mucosa intersection_of: UBERON:0000344 ! mucosa intersection_of: BFO:0000050 UBERON:0002108 ! part of small intestine relationship: BFO:0000050 UBERON:0001168 ! part of wall of small intestine relationship: BFO:0000050 UBERON:0001242 ! part of intestinal mucosa [Term] id: UBERON:0001205 name: submucosa of small intestine namespace: uberon def: "Submucosal tissue in the small intestines." [Wikipedia:Small_intestinal_submucosa] synonym: "small bowel submucosa" EXACT [OBOL:automatic] synonym: "small intestinal submucosa" EXACT [] synonym: "small intestine submucosa" EXACT [] synonym: "submucosa of small bowel" EXACT [OBOL:automatic] synonym: "tela submucosa (intestinum tenue)" EXACT [] xref: BTO:0002112 xref: EMAPA:37564 {source="MA:th"} xref: FMA:14934 xref: MA:0001562 xref: NCIT:C33572 xref: SCTID:691000 xref: UMLS:C0227268 {source="ncithesaurus:Small_Intestinal_Submucosa"} xref: Wikipedia:Small_intestinal_submucosa is_a: UBERON:0009566 ! intestinal submucosa intersection_of: UBERON:0000009 ! submucosa intersection_of: BFO:0000050 UBERON:0002108 ! part of small intestine relationship: BFO:0000050 UBERON:0001168 ! part of wall of small intestine [Term] id: UBERON:0001206 name: serosa of small intestine namespace: uberon def: "A serous membrane that is part of a small intestine [Automatically generated definition]." [OBOL:automatic] synonym: "serosa of small bowel" EXACT [OBOL:automatic] synonym: "serous coat of small intestine" EXACT [] synonym: "serous membrane of small bowel" EXACT [OBOL:automatic] synonym: "serous membrane of small intestine" EXACT [OBOL:automatic] synonym: "small bowel serosa" EXACT [OBOL:automatic] synonym: "small bowel serous membrane" EXACT [OBOL:automatic] synonym: "small intestinal serosa" EXACT [] synonym: "small intestine serosa" EXACT [] synonym: "small intestine serous membrane" EXACT [OBOL:automatic] synonym: "tunica serosa (intestinum tenue)" EXACT [] synonym: "visceral peritoneum of small intestine" EXACT [] xref: EMAPA:37561 {source="MA:th"} xref: FMA:14938 xref: MA:0001558 xref: SCTID:8266009 is_a: UBERON:0001243 ! serosa of intestine intersection_of: UBERON:0000042 ! serous membrane intersection_of: BFO:0000050 UBERON:0002108 ! part of small intestine relationship: BFO:0000050 UBERON:0001168 ! part of wall of small intestine relationship: BFO:0000050 UBERON:0001243 ! part of serosa of intestine [Term] id: UBERON:0001207 name: mucosa of large intestine namespace: uberon def: "A mucosa that is part of a large intestine [Automatically generated definition]." [OBOL:automatic] synonym: "large intestinal mucosa" EXACT [] synonym: "large intestine mucosa" EXACT [] synonym: "large intestine mucosa of organ" EXACT [OBOL:automatic] synonym: "large intestine mucous membrane" EXACT [OBOL:automatic] synonym: "large intestine organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of organ of large intestine" EXACT [OBOL:automatic] synonym: "mucous membrane of large intestine" EXACT [] synonym: "organ mucosa of large intestine" EXACT [OBOL:automatic] xref: CALOHA:TS-2106 xref: EMAPA:35467 xref: FMA:14969 xref: MA:0002688 xref: NCIT:C32926 xref: UMLS:C0734203 {source="ncithesaurus:Large_Intestinal_Mucosa"} is_a: UBERON:0001242 ! intestinal mucosa intersection_of: UBERON:0000344 ! mucosa intersection_of: BFO:0000050 UBERON:0000059 ! part of large intestine relationship: BFO:0000050 UBERON:0001169 ! part of wall of large intestine relationship: BFO:0000050 UBERON:0001242 ! part of intestinal mucosa [Term] id: UBERON:0001208 name: submucosa of large intestine namespace: uberon def: "A submucosa that is part of a large intestine [Automatically generated definition]." [OBOL:automatic] synonym: "large intestinal submucosa" EXACT [] synonym: "large intestine submucosa" EXACT [] xref: BTO:0002111 xref: EMAPA:37560 {source="MA:th"} xref: FMA:14970 xref: MA:0002690 xref: NCIT:C32930 xref: UMLS:C0734204 {source="ncithesaurus:Large_Intestinal_Submucosa"} is_a: UBERON:0009566 ! intestinal submucosa intersection_of: UBERON:0000009 ! submucosa intersection_of: BFO:0000050 UBERON:0000059 ! part of large intestine relationship: BFO:0000050 UBERON:0001169 ! part of wall of large intestine [Term] id: UBERON:0001209 name: serosa of large intestine namespace: uberon def: "A serous membrane that is part of a large intestine [Automatically generated definition]." [OBOL:automatic] synonym: "large intestinal serosa" EXACT [] synonym: "large intestine serosa" EXACT [] synonym: "large intestine serous membrane" EXACT [OBOL:automatic] synonym: "serous coat of large intestine" EXACT [] synonym: "serous membrane of large intestine" EXACT [OBOL:automatic] synonym: "visceral peritoneum of large intestine" EXACT [] xref: EMAPA:37557 {source="MA:th"} xref: FMA:14975 xref: MA:0001546 xref: NCIT:C32929 xref: UMLS:C1517727 {source="ncithesaurus:Large_Intestinal_Serosal_Surface"} is_a: UBERON:0001243 ! serosa of intestine intersection_of: UBERON:0000042 ! serous membrane intersection_of: BFO:0000050 UBERON:0000059 ! part of large intestine relationship: BFO:0000050 UBERON:0001169 ! part of wall of large intestine relationship: BFO:0000050 UBERON:0001243 ! part of serosa of intestine [Term] id: UBERON:0001212 name: duodenal gland namespace: uberon def: "A compound tubular submucosal gland found in that portion of the duodenum which is above the hepatopancreatic sphincter (Sphincter of Oddi). The main function of these glands is to produce a mucus-rich alkaline secretion (containing bicarbonate)[WP]." [Wikipedia:Brunner's_glands] synonym: "Brunner's gland" EXACT [FMA:15060] synonym: "gland of Brunner" EXACT [FMA:15060] synonym: "submucosal gland of duodenum" EXACT [] xref: BTO:0002376 xref: EMAPA:36522 xref: FMA:15060 xref: GAID:314 xref: MA:0001551 xref: MESH:D002011 xref: NCIT:C13010 xref: SCTID:41298001 xref: UMLS:C0006323 {source="ncithesaurus:Brunner_s_Gland"} xref: Wikipedia:Brunner's_glands is_a: UBERON:0003408 ! gland of digestive tract is_a: UBERON:0011148 ! submucosal gland intersection_of: UBERON:0011148 ! submucosal gland intersection_of: BFO:0000050 UBERON:0002114 ! part of duodenum relationship: BFO:0000050 UBERON:0002114 ! part of duodenum relationship: RO:0001025 UBERON:0003332 {source="FMA, modified"} ! located in submucosa of duodenum relationship: RO:0002160 NCBITaxon:40674 ! only in taxon Mammalia [Term] id: UBERON:0001213 name: intestinal villus namespace: uberon def: "The tiny hair-like projections that protrude from the inside of the small intestine that contain blood vessels that capture digested nutrients that are absorbed through the intestinal wall; the villi increase the absorptive surface area of the small intestine by approximately 30-fold." [MGI:csmith, MGI:rbabiuk, MP:0008108] synonym: "enteric villous" EXACT [HP:0011473] synonym: "enteric villus" EXACT [HP:0011473] synonym: "villus" EXACT [BTO:0003121] synonym: "villus intestinalis (intestinum tenue)" EXACT [FMA:15072] xref: BTO:0003121 xref: EMAPA:35784 xref: FMA:15072 xref: MA:0001563 xref: NCIT:C33874 xref: SCTID:23230007 xref: TAO:0005125 xref: UMLS:C1519988 {source="ncithesaurus:Villus"} xref: Wikipedia:Intestinal_villus xref: ZFA:0005125 is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0004923 {source="FMA"} ! organ component layer relationship: BFO:0000050 UBERON:0001277 {source="ZFA"} ! part of intestinal epithelium relationship: BFO:0000051 UBERON:0001981 ! has part blood vessel relationship: BFO:0000051 UBERON:0012425 ! has part striated border microvillus layer property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/3/38/Small_intestine_low_mag.jpg" xsd:anyURI [Term] id: UBERON:0001215 name: inferior mesenteric vein namespace: uberon def: "A blood vessel that drains blood from the large intestine that usually terminates when reaching the splenic vein, which goes on to form the portal vein with the superior mesenteric vein (SMV). Anatomical variations include the IMV draining into the confluence of the SMV and splenic vein and the IMV draining in the SMV. The IMV lies to the right of the similarly name artery, the inferior mesenteric artery, which originates from the abdominal aorta. [WP,unvetted]." [Wikipedia:Inferior_mesenteric_vein] xref: BTO:0002782 xref: EHDAA2:0000819 xref: EHDAA:8712 xref: EMAPA:18642 xref: FMA:15391 xref: MA:0002178 xref: NCIT:C32782 xref: SCTID:281055007 xref: UMLS:C0226754 {source="ncithesaurus:Inferior_Mesenteric_Vein"} xref: VHOG:0001118 xref: Wikipedia:Inferior_mesenteric_vein is_a: UBERON:0005617 ! mesenteric vein intersection_of: UBERON:0005617 ! mesenteric vein intersection_of: RO:0002179 UBERON:0000059 ! drains large intestine relationship: RO:0002179 UBERON:0000059 ! drains large intestine relationship: RO:0002376 UBERON:0003713 {source="FMA/obol"} ! tributary of splenic vein property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/3/33/Gray591.png" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI [Term] id: UBERON:0001222 name: right ureter namespace: uberon def: "An ureter that is part of a right side of organism [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:37373 {source="MA:th"} xref: FMA:15571 xref: MA:0001685 xref: NCIT:C49327 xref: SCTID:276251000 xref: UMLS:C0227682 {source="ncithesaurus:Right_Ureter"} is_a: UBERON:0000056 ! ureter intersection_of: UBERON:0000056 ! ureter intersection_of: BSPO:0000121 UBERON:0000468 ! in right side of multicellular organism relationship: BSPO:0000121 UBERON:0000468 ! in right side of multicellular organism property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Ureter_R.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Ureter_R.glb" xsd:anyURI [Term] id: UBERON:0001223 name: left ureter namespace: uberon def: "An ureter that is part of a left side of organism [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:37372 {source="MA:th"} xref: FMA:15572 xref: MA:0001684 xref: NCIT:C49324 xref: SCTID:276340002 xref: UMLS:C0227683 {source="ncithesaurus:Left_Ureter"} is_a: UBERON:0000056 ! ureter intersection_of: UBERON:0000056 ! ureter intersection_of: BSPO:0000120 UBERON:0000468 ! in left side of multicellular organism relationship: BSPO:0000120 UBERON:0000468 ! in left side of multicellular organism property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Ureter_L.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Ureter_L.glb" xsd:anyURI [Term] id: UBERON:0001224 name: renal pelvis namespace: uberon def: "A funnel shaped proximal portion of the ureter that is formed by convergence of the major calices [MP]." [MP:0004194] synonym: "kidney pelvis" EXACT [] synonym: "pelvis of ureter" EXACT [] xref: CALOHA:TS-2230 xref: EMAPA:17948 xref: FMA:15575 xref: GAID:426 xref: galen:RenalPelvis xref: MA:0000374 xref: MESH:D007682 xref: NCIT:C12887 xref: SCTID:362221007 xref: UMLS:C0227666 {source="ncithesaurus:Renal_Pelvis"} xref: Wikipedia:Renal_pelvis is_a: UBERON:0000064 ! organ part is_a: UBERON:0004111 ! anatomical conduit disjoint_from: UBERON:0002355 ! pelvic region of trunk relationship: BFO:0000050 UBERON:0002113 {source="MA"} ! part of kidney relationship: BFO:0000050 UBERON:0036295 ! part of renal pelvis/ureter relationship: channel_for UBERON:0001088 ! urine relationship: channels_from UBERON:0002113 ! kidney relationship: channels_into UBERON:0000056 ! ureter relationship: RO:0002150 UBERON:0000056 {source="FMA"} ! continuous with ureter relationship: RO:0002433 UBERON:0000056 ! contributes to morphology of ureter property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/c/c0/Illu_kidney2.jpg" xsd:anyURI [Term] id: UBERON:0001225 name: cortex of kidney namespace: uberon def: "Outer cortical portion of the kidney, between the renal capsule and the renal medulla." [Wikipedia:Renal_cortex] synonym: "kidney cortex" EXACT [] synonym: "renal cortex" EXACT [] xref: BTO:0001166 xref: CALOHA:TS-0503 xref: EMAPA:17952 xref: FMA:15581 xref: GAID:424 xref: galen:CortexOfKidney xref: MA:0000372 xref: MESH:D007672 xref: NCIT:C12739 xref: SCTID:362211004 xref: UMLS:C0022655 {source="ncithesaurus:Renal_Cortex"} xref: Wikipedia:Renal_cortex is_a: UBERON:0001851 ! cortex intersection_of: UBERON:0001851 ! cortex intersection_of: BFO:0000050 UBERON:0002113 ! part of kidney relationship: BFO:0000050 UBERON:0008987 {source="FMA"} ! part of renal parenchyma relationship: RO:0002433 UBERON:0002113 ! contributes to morphology of kidney property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Kidney_L.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Kidney_R.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Kidney_L.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Kidney_R.glb" xsd:anyURI property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/6/69/Illu_kidney.jpg" xsd:anyURI [Term] id: UBERON:0001231 name: nephron tubule namespace: uberon def: "An epithelial tube that is part of the nephron, the functional part of the kidney." [GO:0072078, Wikipedia:Renal_tubule] synonym: "kidney tubule" EXACT [GAID:433] synonym: "tubulus renalis" EXACT [] xref: BTO:0000343 xref: CALOHA:TS-1262 xref: EFO:0003666 xref: EMAPA:27782 xref: EV:0100387 xref: FMA:15627 xref: GAID:433 xref: MA:0000377 xref: MESH:D007684 xref: NCIT:C49274 xref: SCTID:361332007 xref: TAO:0001287 xref: UMLS:C0022674 {source="ncithesaurus:Renal_Tubule"} xref: Wikipedia:Renal_tubule xref: ZFA:0001287 is_a: UBERON:0004211 ! nephron epithelium is_a: UBERON:0009773 {source="GO"} ! renal tubule intersection_of: UBERON:0003914 {source="GO", source="MA", source="ZFA"} ! epithelial tube intersection_of: BFO:0000050 UBERON:0001285 {source="GO", source="MA", source="ZFA"} ! part of nephron relationship: BFO:0000051 CL:0005009 {source="ZFA"} ! has part renal principal cell relationship: RO:0002202 UBERON:0003918 ! develops from kidney mesenchyme relationship: RO:0002433 UBERON:0001285 ! contributes to morphology of nephron [Term] id: UBERON:0001232 name: collecting duct of renal tubule namespace: uberon def: "The collecting duct is a portion of the nephron through which water flows, moving passively down its concentration gradient." [GO:0072044, Wikipedia:Collecting_tubule] synonym: "collecting duct" EXACT [GO:0072044] synonym: "kidney collecting duct" EXACT [] synonym: "renal collecting tubule" EXACT [FMA:15628] synonym: "tubulus renalis colligens" EXACT [] xref: BTO:0000761 xref: CALOHA:TS-0860 xref: EMAPA:28407 xref: EV:0100391 xref: FMA:15628 xref: GAID:434 xref: MA:0000371 xref: MESH:D007685 xref: SCTID:28202009 xref: TAO:0005294 xref: Wikipedia:Collecting_tubule xref: ZFA:0005294 is_a: UBERON:0006555 ! excretory tube relationship: BFO:0000050 UBERON:0001285 ! part of nephron relationship: BFO:0000050 UBERON:0004100 ! part of renal collecting system relationship: RO:0002433 UBERON:0002113 ! contributes to morphology of kidney [Term] id: UBERON:0001238 name: lamina propria of small intestine namespace: uberon def: "Lamina propria that is part_of the small intestine." [GOC:Obol] synonym: "lamina propria mucosa of small bowel" EXACT [OBOL:automatic] synonym: "lamina propria mucosa of small intestine" EXACT [OBOL:automatic] synonym: "lamina propria mucosae of small bowel" EXACT [OBOL:automatic] synonym: "lamina propria mucosae of small intestine" EXACT [] synonym: "lamina propria of mucosa of small intestine" EXACT [] synonym: "lamina propria of small bowel" EXACT [OBOL:automatic] synonym: "small bowel lamina propria" EXACT [OBOL:automatic] synonym: "small bowel lamina propria mucosa" EXACT [OBOL:automatic] synonym: "small bowel lamina propria mucosae" EXACT [OBOL:automatic] synonym: "small intestine lamina propria" EXACT [] synonym: "small intestine lamina propria mucosa" EXACT [OBOL:automatic] synonym: "small intestine lamina propria mucosae" EXACT [OBOL:automatic] xref: EMAPA:35779 xref: FMA:15651 xref: MA:0001554 xref: NCIT:C49297 xref: SCTID:63588008 xref: UMLS:C1711325 {source="ncithesaurus:Small_Intestinal_Lamina_Propria"} is_a: UBERON:0004780 ! gastrointestinal system lamina propria intersection_of: UBERON:0000030 ! lamina propria intersection_of: BFO:0000050 UBERON:0002108 ! part of small intestine relationship: BFO:0000050 UBERON:0001204 ! part of mucosa of small intestine [Term] id: UBERON:0001242 name: intestinal mucosa namespace: uberon def: "Mucosal layer that lines the intestine." [UBERON:cjm] synonym: "bowel mucosa" EXACT [OBOL:automatic] synonym: "bowel mucosa of organ" EXACT [OBOL:automatic] synonym: "bowel mucous membrane" EXACT [OBOL:automatic] synonym: "bowel organ mucosa" EXACT [OBOL:automatic] synonym: "intestine mucosa" EXACT [] synonym: "intestine mucosa of organ" EXACT [OBOL:automatic] synonym: "intestine mucous membrane" EXACT [OBOL:automatic] synonym: "intestine organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of bowel" EXACT [OBOL:automatic] synonym: "mucosa of intestine" EXACT [] synonym: "mucosa of organ of bowel" EXACT [OBOL:automatic] synonym: "mucosa of organ of intestine" EXACT [OBOL:automatic] synonym: "mucous membrane of bowel" EXACT [OBOL:automatic] synonym: "mucous membrane of intestine" EXACT [OBOL:automatic] synonym: "organ mucosa of bowel" EXACT [OBOL:automatic] synonym: "organ mucosa of intestine" EXACT [OBOL:automatic] synonym: "tunica mucosa intestini" EXACT [] xref: BTO:0000642 xref: EMAPA:35440 xref: FMA:15695 xref: GAID:296 xref: MA:0001537 xref: MESH:D007413 xref: NCIT:C49241 xref: SCTID:362080002 xref: UMLS:C0021839 {source="ncithesaurus:Intestinal_Mucosa"} is_a: UBERON:0004786 ! gastrointestinal system mucosa intersection_of: UBERON:0000344 ! mucosa intersection_of: BFO:0000050 UBERON:0000160 ! part of intestine relationship: BFO:0000050 UBERON:0001262 ! part of wall of intestine [Term] id: UBERON:0001243 name: serosa of intestine namespace: uberon def: "A serous membrane that is part of a wall of intestine [Automatically generated definition]." [OBOL:automatic] synonym: "anatomical wall of bowel serosa" EXACT [OBOL:automatic] synonym: "anatomical wall of bowel serous membrane" EXACT [OBOL:automatic] synonym: "anatomical wall of intestine serosa" EXACT [OBOL:automatic] synonym: "anatomical wall of intestine serous membrane" EXACT [OBOL:automatic] synonym: "bowel anatomical wall serosa" EXACT [OBOL:automatic] synonym: "bowel anatomical wall serous membrane" EXACT [OBOL:automatic] synonym: "bowel wall serosa" EXACT [OBOL:automatic] synonym: "bowel wall serous membrane" EXACT [OBOL:automatic] synonym: "intestinal serosa" EXACT [] synonym: "intestinal wall serosa" EXACT [OBOL:automatic] synonym: "intestinal wall serous membrane" EXACT [OBOL:automatic] synonym: "intestine anatomical wall serosa" EXACT [OBOL:automatic] synonym: "intestine anatomical wall serous membrane" EXACT [OBOL:automatic] synonym: "intestine serosa" EXACT [] synonym: "intestine wall serosa" EXACT [OBOL:automatic] synonym: "intestine wall serous membrane" EXACT [OBOL:automatic] synonym: "serosa of anatomical wall of bowel" EXACT [OBOL:automatic] synonym: "serosa of anatomical wall of intestine" EXACT [OBOL:automatic] synonym: "serosa of bowel anatomical wall" EXACT [OBOL:automatic] synonym: "serosa of bowel wall" EXACT [OBOL:automatic] synonym: "serosa of intestinal wall" EXACT [OBOL:automatic] synonym: "serosa of intestine anatomical wall" EXACT [OBOL:automatic] synonym: "serosa of intestine wall" EXACT [OBOL:automatic] synonym: "serosa of wall of bowel" EXACT [OBOL:automatic] synonym: "serosa of wall of intestine" EXACT [OBOL:automatic] synonym: "serous membrane of anatomical wall of bowel" EXACT [OBOL:automatic] synonym: "serous membrane of anatomical wall of intestine" EXACT [OBOL:automatic] synonym: "serous membrane of bowel anatomical wall" EXACT [OBOL:automatic] synonym: "serous membrane of bowel wall" EXACT [OBOL:automatic] synonym: "serous membrane of intestinal wall" EXACT [OBOL:automatic] synonym: "serous membrane of intestine anatomical wall" EXACT [OBOL:automatic] synonym: "serous membrane of intestine wall" EXACT [OBOL:automatic] synonym: "serous membrane of wall of bowel" EXACT [OBOL:automatic] synonym: "serous membrane of wall of intestine" EXACT [OBOL:automatic] synonym: "visceral peritoneum of intestine" EXACT [] synonym: "wall of bowel serosa" EXACT [OBOL:automatic] synonym: "wall of bowel serous membrane" EXACT [OBOL:automatic] synonym: "wall of intestine serosa" EXACT [OBOL:automatic] synonym: "wall of intestine serous membrane" EXACT [OBOL:automatic] xref: EMAPA:37619 {source="MA:th"} xref: FMA:15701 xref: MA:0001538 is_a: UBERON:0004782 ! gastrointestinal system serosa intersection_of: UBERON:0000042 ! serous membrane intersection_of: BFO:0000050 UBERON:0000160 ! part of intestine relationship: BFO:0000050 UBERON:0001262 ! part of wall of intestine [Term] id: UBERON:0001245 name: anus namespace: uberon def: "Orifice at the opposite end of an animal's digestive tract from the mouth. Its function is to expel feces, unwanted semi-solid matter produced during digestion, which, depending on the type of animal, may be one or more of: matter which the animal cannot digest, such as bones; food material after all the nutrients have been extracted, for example cellulose or lignin; ingested matter which would be toxic if it remained in the digestive tract; and dead or excess gut bacteria and other endosymbionts." [Wikipedia:Anus, ZFIN:curator] synonym: "anal opening" EXACT [] synonym: "anal orifice" EXACT [] synonym: "opening of terminal part of digestive tract" EXACT [] xref: BTO:0001680 xref: CALOHA:TS-2005 xref: EV:0100082 xref: FMA:15711 xref: GAID:312 xref: galen:Anus xref: MA:0000331 xref: NCIT:C43362 xref: SCTID:181262009 xref: TADS:0000066 xref: TGMA:0001279 xref: UMLS:C0003461 {source="ncithesaurus:Anus"} xref: WBbt:0005364 xref: Wikipedia:Anus is_a: UBERON:0000161 ! orifice is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0000161 ! orifice intersection_of: BSPO:0001108 UBERON:0001555 ! distalmost part of digestive tract relationship: BSPO:0001108 UBERON:0001555 ! distalmost part of digestive tract relationship: RO:0002202 UBERON:0000931 ! develops from proctodeum property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/6/65/Protovsdeuterostomes.svg" xsd:anyURI property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/7/75/Anorectum.gif" xsd:anyURI [Term] id: UBERON:0001246 name: interlobular bile duct namespace: uberon def: "The canals that carry bile in the liver between the intralobular ducts and the biliary ductules; interlobular bile ducts are part of the interlobular portal triad." [MP:0009500] synonym: "interlobular ductule" EXACT [MP:0009500] xref: FMA:15767 xref: MA:0002668 xref: NCIT:C32827 xref: SCTID:83488001 xref: UMLS:C0227515 {source="ncithesaurus:Interlobular_Bile_Duct"} xref: Wikipedia:Interlobular_bile_ducts is_a: UBERON:0003704 {source="FMA", source="MA-part-of"} ! intrahepatic bile duct relationship: BFO:0000050 UBERON:0001279 {source="FMA", source="MA", source="MP"} ! part of portal triad relationship: RO:0002176 UBERON:0004058 ! connects biliary ductule relationship: RO:0002176 UBERON:0014719 ! connects intralobular duct relationship: RO:0002433 UBERON:0001279 ! contributes to morphology of portal triad [Term] id: UBERON:0001252 name: adventitia of ureter namespace: uberon def: "An adventitia that is part of a ureter." [OBOL:automatic] synonym: "external adventitia of ureter" EXACT [] synonym: "ureter adventitia" EXACT [] synonym: "ureteral adventitia" EXACT [] xref: EMAPA:28114 xref: FMA:15892 xref: MA:0002652 xref: SCTID:392273001 xref: SCTID:47879001 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005742 ! adventitia intersection_of: UBERON:0005742 ! adventitia intersection_of: BFO:0000050 UBERON:0000056 ! part of ureter relationship: BFO:0000050 UBERON:0009916 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! part of wall of ureter [Term] id: UBERON:0001253 name: lamina propria of ureter namespace: uberon def: "A lamina propria that is part of a ureter [Automatically generated definition]." [OBOL:automatic] synonym: "lamina propria mucosa of ureter" EXACT [OBOL:automatic] synonym: "lamina propria mucosae of ureter" EXACT [OBOL:automatic] synonym: "ureter lamina propria" EXACT [] synonym: "ureter lamina propria mucosa" EXACT [OBOL:automatic] synonym: "ureter lamina propria mucosae" EXACT [OBOL:automatic] xref: EMAPA:28841 xref: FMA:15896 xref: MA:0002653 xref: SCTID:2771005 is_a: UBERON:0000030 ! lamina propria is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0000030 ! lamina propria intersection_of: BFO:0000050 UBERON:0000056 ! part of ureter relationship: BFO:0000050 UBERON:0004980 ! part of mucosa of ureter [Term] id: UBERON:0001255 name: urinary bladder namespace: uberon def: "Distensible musculomembranous organ situated in the anterior part of the pelvic cavity in which urine collects before excretion[MP]." [MGI:anna, Wikipedia:Urinary_bladder] xref: AAO:0000623 xref: BTO:0001418 xref: CALOHA:TS-1090 xref: EFO:0000290 xref: EHDAA2:0000174 xref: EHDAA:9328 xref: EMAPA:18321 xref: EV:0100098 xref: FMA:15900 xref: GAID:0000004 xref: galen:UrinaryBladder xref: MA:0000380 xref: MAT:0000122 xref: MESH:D001743 xref: MIAA:0000122 xref: NCIT:C12414 xref: SCTID:302512001 xref: UMLS:C0005682 {source="ncithesaurus:Bladder"} xref: VHOG:0000740 xref: Wikipedia:Urinary_bladder xref: XAO:0000154 is_a: UBERON:0002075 ! viscus is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0018707 {source="BTO"} ! bladder organ relationship: BFO:0000050 UBERON:0001556 {source="FMA"} ! part of lower urinary tract relationship: RO:0002202 UBERON:0000164 ! develops from primitive urogenital sinus property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Urinary_Bladder.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Urinary_Bladder.glb" xsd:anyURI property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/3/30/Urinary_system.svg" xsd:anyURI [Term] id: UBERON:0001256 name: wall of urinary bladder namespace: uberon def: "An anatomical wall that lines the insider of a urinary bladder." [http://orcid.org/0000-0002-6601-2165] synonym: "anatomical wall of bladder" EXACT [OBOL:automatic] synonym: "anatomical wall of urinary bladder" EXACT [OBOL:automatic] synonym: "bladder anatomical wall" EXACT [OBOL:automatic] synonym: "bladder wall" EXACT [OBOL:automatic] synonym: "urinary bladder anatomical wall" EXACT [OBOL:automatic] synonym: "urinary bladder wall" EXACT [] synonym: "wall of bladder" EXACT [OBOL:automatic] xref: BTO:0001462 xref: EMAPA:35175 xref: FMA:15902 xref: MA:0002493 xref: NCIT:C48941 xref: SCTID:362225003 xref: UMLS:C0458421 {source="ncithesaurus:Bladder_Wall"} is_a: UBERON:0000060 ! anatomical wall is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0000060 ! anatomical wall intersection_of: BFO:0000050 UBERON:0001255 ! part of urinary bladder relationship: BFO:0000050 UBERON:0001255 ! part of urinary bladder [Term] id: UBERON:0001259 name: mucosa of urinary bladder namespace: uberon def: "The mucous membrane lining the urinary bladder." [MGI:anna, MP:0011766] synonym: "bladder mucosa" EXACT [] synonym: "bladder mucous membrane" EXACT [OBOL:automatic] synonym: "bladder organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of bladder" EXACT [OBOL:automatic] synonym: "mucous membrane of bladder" EXACT [] synonym: "mucous membrane of urinary bladder" EXACT [] synonym: "tunica mucosa vesicae urinariae" EXACT [MP:MP] synonym: "urinary bladder mucosa" EXACT [] synonym: "urinary bladder mucous membrane" EXACT [OBOL:automatic] xref: EFO:0000293 xref: EMAPA:35897 xref: FMA:15928 xref: galen:MucousMembraneOfUrinaryBladder xref: MA:0001692 xref: NCIT:C32205 xref: SCTID:362224004 xref: UMLS:C0227691 {source="ncithesaurus:Bladder_Mucosa"} is_a: UBERON:0000344 ! mucosa is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0000344 ! mucosa intersection_of: BFO:0000050 UBERON:0001255 ! part of urinary bladder relationship: BFO:0000050 UBERON:0001256 ! part of wall of urinary bladder relationship: RO:0002433 UBERON:0001255 ! contributes to morphology of urinary bladder [Term] id: UBERON:0001260 name: serosa of urinary bladder namespace: uberon def: "A serous membrane that is part of a urinary bladder [Automatically generated definition]." [OBOL:automatic] synonym: "bladder serosa" EXACT [] synonym: "bladder serous membrane" EXACT [OBOL:automatic] synonym: "serosa of bladder" EXACT [] synonym: "serous coat of bladder" EXACT [] synonym: "serous coat of urinary bladder" EXACT [] synonym: "serous membrane of bladder" EXACT [OBOL:automatic] synonym: "serous membrane of urinary bladder" EXACT [OBOL:automatic] synonym: "urinary bladder serosa" EXACT [] synonym: "urinary bladder serous membrane" EXACT [OBOL:automatic] synonym: "visceral peritoneum of urinary bladder" EXACT [] xref: EMAPA:28661 xref: FMA:15932 xref: MA:0001696 xref: SCTID:5868002 is_a: UBERON:0000042 ! serous membrane intersection_of: UBERON:0000042 ! serous membrane intersection_of: BFO:0000050 UBERON:0001255 ! part of urinary bladder relationship: BFO:0000050 UBERON:0001256 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! part of wall of urinary bladder [Term] id: UBERON:0001261 name: lamina propria of urinary bladder namespace: uberon def: "A lamina propria that is part of a urinary bladder [Automatically generated definition]." [OBOL:automatic] synonym: "bladder lamina propria" EXACT [OBOL:automatic] synonym: "bladder lamina propria mucosa" EXACT [OBOL:automatic] synonym: "bladder lamina propria mucosae" EXACT [OBOL:automatic] synonym: "lamina propria mucosa of bladder" EXACT [OBOL:automatic] synonym: "lamina propria mucosa of urinary bladder" EXACT [OBOL:automatic] synonym: "lamina propria mucosae of bladder" EXACT [OBOL:automatic] synonym: "lamina propria mucosae of urinary bladder" EXACT [OBOL:automatic] synonym: "lamina propria of bladder" EXACT [OBOL:automatic] synonym: "urinary bladder lamina propria" EXACT [] synonym: "urinary bladder lamina propria mucosa" EXACT [OBOL:automatic] synonym: "urinary bladder lamina propria mucosae" EXACT [OBOL:automatic] xref: EMAPA:30088 xref: FMA:15935 xref: MA:0001695 xref: NCIT:C48940 xref: UMLS:C1706967 {source="ncithesaurus:Bladder_Lamina_Propria"} is_a: UBERON:0000030 ! lamina propria is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0000030 ! lamina propria intersection_of: BFO:0000050 UBERON:0001255 ! part of urinary bladder relationship: BFO:0000050 UBERON:0001259 ! part of mucosa of urinary bladder [Term] id: UBERON:0001262 name: wall of intestine namespace: uberon def: "An anatomical wall that is part of a intestine [Automatically generated definition]." [OBOL:automatic] synonym: "anatomical wall of bowel" EXACT [OBOL:automatic] synonym: "anatomical wall of intestine" EXACT [OBOL:automatic] synonym: "bowel anatomical wall" EXACT [OBOL:automatic] synonym: "bowel wall" EXACT [OBOL:automatic] synonym: "intestinal wall" EXACT [] synonym: "intestine anatomical wall" EXACT [OBOL:automatic] synonym: "intestine wall" EXACT [] synonym: "wall of bowel" EXACT [OBOL:automatic] xref: BTO:0000647 xref: EMAPA:35444 xref: FMA:15949 xref: MA:0001525 xref: MA:0002693 xref: NCIT:C49478 xref: UMLS:C1708548 {source="ncithesaurus:Intestinal_Wall_Tissue"} is_a: UBERON:0000328 ! gut wall intersection_of: UBERON:0000060 ! anatomical wall intersection_of: BFO:0000050 UBERON:0000160 ! part of intestine relationship: BFO:0000050 UBERON:0000160 ! part of intestine [Term] id: UBERON:0001263 name: pancreatic acinus namespace: uberon def: "The secretory units of the exocrine pancreas, where fluid containing digestive enzymes is produced; consists of a group of secretory cells surrounding a luminal space that connects to the pancreatic duct." [MP:0009145] synonym: "pancreas acinus" EXACT [] xref: EMAPA:35651 xref: FMA:16011 xref: MA:0002417 xref: NCIT:C49268 xref: SCTID:247604006 xref: UMLS:C0227578 {source="ncithesaurus:Pancreatic_Acinus"} is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0013232 ! serous acinus intersection_of: UBERON:0009842 ! glandular acinus intersection_of: BFO:0000050 UBERON:0000017 ! part of exocrine pancreas relationship: BFO:0000050 UBERON:0007324 {source="FMA"} ! part of pancreatic lobule relationship: RO:0002433 UBERON:0000017 ! contributes to morphology of exocrine pancreas relationship: RO:0002473 CL:0002064 ! composed primarily of pancreatic acinar cell [Term] id: UBERON:0001264 name: pancreas namespace: uberon def: "An endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating hormones[GO]." [GO:0031016] xref: AAO:0010112 xref: BTO:0000988 xref: CALOHA:TS-0736 xref: EFO:0000855 xref: EHDAA2:0001367 xref: EHDAA:6893 xref: EMAPA:17503 xref: EV:0100092 xref: FMA:7198 xref: GAID:334 xref: galen:Pancreas xref: MA:0000120 xref: MAT:0000075 xref: MESH:D010179 xref: MIAA:0000075 xref: NCIT:C12393 xref: SCTID:181277001 xref: TAO:0000140 xref: UMLS:C0030274 {source="ncithesaurus:Pancreas"} xref: VHOG:0000050 xref: Wikipedia:Pancreas xref: XAO:0000136 xref: ZFA:0000140 is_a: UBERON:0002075 ! viscus relationship: BFO:0000051 UBERON:0000016 ! has part endocrine pancreas relationship: BFO:0000051 UBERON:0000017 {gci_filler="NCBITaxon:89593", gci_relation="BFO:0000050"} ! has part exocrine pancreas relationship: RO:0002160 NCBITaxon:7742 {source="PMID:16417468"} ! only in taxon Vertebrata relationship: RO:0002254 UBERON:0003924 {source="Wikipedia"} ! has developmental contribution from ventral pancreatic bud property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Pancreas.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Pancreas.glb" xsd:anyURI property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/7/7e/Blausen_0699_PancreasAnatomy2.png" xsd:anyURI [Term] id: UBERON:0001265 name: trabecula of spleen namespace: uberon def: "A trabecula that is part of a spleen." [OBOL:automatic] synonym: "spleen trabeculum" EXACT [] synonym: "splenic trabecula" EXACT [] xref: EMAPA:35808 xref: FMA:16027 xref: MA:0000758 xref: NCIT:C33607 xref: SCTID:61987002 xref: UMLS:C0229688 {source="ncithesaurus:Splenic_Trabecula"} xref: Wikipedia:Trabeculae_of_spleen is_a: UBERON:0000440 ! trabecula is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0000440 ! trabecula intersection_of: BFO:0000050 UBERON:0002106 ! part of spleen relationship: BFO:0000050 UBERON:1000024 {source="FMA"} ! part of parenchyma of spleen [Term] id: UBERON:0001268 name: peritoneal fluid namespace: uberon def: "Transudate contained in the peritoneal cavity." [FMA:16515] xref: BTO:0001031 xref: EMAPA:35683 xref: FMA:16515 xref: MA:0002531 xref: ncithesaurus:Peritoneal_Fluid xref: Wikipedia:Peritoneal_fluid is_a: UBERON:0007779 ! transudate is_a: UBERON:0007794 {source="FMA"} ! secretion of serous gland is_a: UBERON:0036217 ! coelomic fluid intersection_of: UBERON:0007779 ! transudate intersection_of: RO:0001025 UBERON:0001179 ! located in peritoneal cavity relationship: RO:0001025 UBERON:0001179 ! located in peritoneal cavity [Term] id: UBERON:0001271 name: pelvic girdle region namespace: uberon def: "The organism subdivision that includes the pelvic girdle skeleton and associated soft tissue. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc). Examples: There are only two instances in an organism, right and left pelvic girdle regions." [DOI:10.1002/dvdy.22617, FMA:16581, FMA:23217, https://groups.google.com/d/topic/obo-anatomy/h4R4xKmINrw/discussion, https://orcid.org/0000-0002-6601-2165, UBERONREF:0000003] xref: EMAPA:37862 {source="MA:th"} xref: FMA:16581 xref: NCIT:C33291 xref: SCTID:360010001 xref: UMLS:C0684083 {source="ncithesaurus:Pelvic_Girdle"} xref: VSAO:0000304 is_a: UBERON:0007823 ! appendage girdle region is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0007823 ! appendage girdle region intersection_of: BFO:0000050 UBERON:0010709 ! part of pelvic complex disjoint_from: UBERON:0007832 ! pelvic girdle skeleton relationship: BFO:0000050 UBERON:0010709 ! part of pelvic complex relationship: BSPO:0000126 UBERON:0002355 ! in lateral side of pelvic region of trunk relationship: RO:0002551 UBERON:0007832 ! has skeleton pelvic girdle skeleton property_value: IAO:0000232 "this class describes the subdivision of the limb/fin, NOT the skeleton within. See also: skeleton of pectoral girdle (UBERON:0007831). See also comments on obo-anatomy mail list. Note that even though the class includes soft tissue it is more restrictive than 'pelvis' which also includes structures in cavities etc. TODO this needs to be better documented" xsd:string [Term] id: UBERON:0001276 name: epithelium of stomach namespace: uberon def: "The epithelial layer of the stomach ." [MP:0000471] synonym: "epithelial tissue of stomach" EXACT [OBOL:automatic] synonym: "epithelial tissue of ventriculus" EXACT [OBOL:automatic] synonym: "epithelium of ventriculus" EXACT [OBOL:automatic] synonym: "stomach epithelial tissue" EXACT [OBOL:automatic] synonym: "stomach epithelium" EXACT [OBOL:automatic] synonym: "ventriculus epithelial tissue" EXACT [OBOL:automatic] synonym: "ventriculus epithelium" EXACT [OBOL:automatic] xref: BTO:0000500 xref: CALOHA:TS-2068 xref: EHDAA2:0001918 xref: EMAPA:17023 xref: FMA:17091 xref: MA:0001610 xref: SCTID:64977002 xref: VHOG:0001433 is_a: UBERON:0000485 ! simple columnar epithelium is_a: UBERON:0003350 ! epithelium of mucosa is_a: UBERON:0004808 ! gastrointestinal system epithelium is_a: UBERON:0015833 ! foregut epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: BFO:0000050 UBERON:0000945 ! part of stomach relationship: BFO:0000050 UBERON:0001199 ! part of mucosa of stomach relationship: RO:0002433 UBERON:0001199 ! contributes to morphology of mucosa of stomach [Term] id: UBERON:0001277 name: intestinal epithelium namespace: uberon def: "Epithelial layer that lines the intestine." [UBERON:cjm] synonym: "bowel epithelial tissue" EXACT [OBOL:automatic] synonym: "bowel epithelium" EXACT [OBOL:automatic] synonym: "epithelial tissue of bowel" EXACT [OBOL:automatic] synonym: "epithelial tissue of intestine" EXACT [OBOL:automatic] synonym: "epithelium of bowel" EXACT [OBOL:automatic] synonym: "epithelium of intestine" EXACT [OBOL:automatic] synonym: "intestine epithelial tissue" EXACT [OBOL:automatic] xref: BTO:0000781 xref: EMAPA:32873 xref: FMA:17229 xref: MA:0001536 xref: NCIT:C49240 xref: SCTID:266135004 xref: TAO:0005124 xref: UMLS:C0226890 {source="ncithesaurus:Intestinal_Epithelium"} xref: Wikipedia:Intestinal_epithelium xref: ZFA:0005124 is_a: UBERON:0000485 ! simple columnar epithelium is_a: UBERON:0003350 ! epithelium of mucosa is_a: UBERON:0003929 ! digestive tract epithelium is_a: UBERON:0004808 ! gastrointestinal system epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: BFO:0000050 UBERON:0000160 ! part of intestine relationship: BFO:0000050 UBERON:0001242 ! part of intestinal mucosa relationship: RO:0002433 UBERON:0000160 ! contributes to morphology of intestine [Term] id: UBERON:0001278 name: epithelium of large intestine namespace: uberon def: "An epithelium that is part of a large intestine [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of large intestine" EXACT [OBOL:automatic] synonym: "large intestinal epithelium" EXACT [] synonym: "large intestine epithelial tissue" EXACT [OBOL:automatic] synonym: "large intestine epithelium" EXACT [] xref: CALOHA:TS-2105 xref: EMAPA:35466 xref: FMA:17301 xref: MA:0001545 is_a: UBERON:0001277 ! intestinal epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: BFO:0000050 UBERON:0000059 ! part of large intestine relationship: BFO:0000050 UBERON:0001207 ! part of mucosa of large intestine [Term] id: UBERON:0001279 name: portal triad namespace: uberon def: "A multi-organ-part structure that consists of three vessels of the portal lobule including the bile duct, a terminal branch of the hepatic artery and portal vein, and may also include a lymphatic vessel." [http://orcid.org/0000-0002-6601-2165, ISBN:0-683-40008-8, MGI:csmith, MP:0008993] synonym: "trias hepatica" EXACT [] xref: FMA:17523 xref: MA:0002499 xref: NCIT:C33342 xref: SCTID:362192000 xref: UMLS:C0227514 {source="ncithesaurus:Portal_Triad"} xref: Wikipedia:Portal_triad is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0034921 ! multi organ part structure relationship: BFO:0000050 UBERON:0001172 ! part of hepatic acinus relationship: BFO:0000051 UBERON:0001193 ! has part hepatic artery relationship: BFO:0000051 UBERON:0002017 ! has part portal vein relationship: BFO:0000051 UBERON:0003704 ! has part intrahepatic bile duct relationship: RO:0002433 UBERON:0001171 ! contributes to morphology of portal lobule property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/6/62/Portal_triad.JPG" xsd:anyURI [Term] id: UBERON:0001280 name: liver parenchyma namespace: uberon def: "The functional units of the liver including the lobules." [MP:0008986] synonym: "hepatic parenchyma" EXACT [FMA:17540] synonym: "liver parenchyme" EXACT [XAO:0000454] synonym: "parenchyma of liver" EXACT [FMA:17540] xref: AAO:0010405 xref: EHDAA2:0001004 xref: EHDAA:2201 xref: EMAPA:17203 xref: FMA:17540 xref: MA:0000366 xref: NCIT:C32735 xref: SCTID:363535004 xref: UMLS:C0736268 xref: VHOG:0000539 xref: XAO:0000454 is_a: UBERON:0000353 ! parenchyma is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: UBERON:0000353 ! parenchyma intersection_of: BFO:0000050 UBERON:0002107 ! part of liver relationship: BFO:0000050 UBERON:0002107 ! part of liver relationship: RO:0002202 UBERON:0008835 {source="XAO"} ! develops from hepatic diverticulum relationship: RO:0002433 UBERON:0002107 ! contributes to morphology of liver [Term] id: UBERON:0001281 name: hepatic sinusoid namespace: uberon def: "Wide thin-walled blood vessels in the liver. In mammals they have neither veinous or arterial markers." [Wikipedia:Hepatic_sinusoid, ZFIN:curator] synonym: "liver hepatic sinusoids" EXACT [EHDAA2:0000999] synonym: "liver sinusoid" EXACT [] synonym: "liver sinusoidal blood vessel" EXACT [OBOL:automatic] synonym: "sinusoid of liver" EXACT [OBOL:automatic] synonym: "sinusoidal blood vessel of liver" EXACT [OBOL:automatic] synonym: "vas capillare sinusoideum" EXACT [] xref: EHDAA2:0000999 xref: EMAPA:17365 xref: FMA:17543 xref: MA:0000367 xref: NCIT:C32733 xref: SCTID:67435004 xref: TAO:0005091 xref: UMLS:C0227523 {source="ncithesaurus:Hepatic_Sinusoid"} xref: VHOG:0000708 xref: Wikipedia:Hepatic_sinusoid xref: ZFA:0005091 is_a: UBERON:0003909 ! sinusoid is_a: UBERON:0005911 ! endo-epithelium is_a: UBERON:0015796 ! liver blood vessel intersection_of: UBERON:0003909 ! sinusoid intersection_of: BFO:0000050 UBERON:0002107 ! part of liver relationship: BFO:0000050 RO:0002577 ! part of system relationship: BFO:0000050 UBERON:0004647 ! part of liver lobule relationship: BFO:0000050 UBERON:0006877 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! part of vasculature of liver relationship: RO:0002170 UBERON:0006841 ! connected to central vein of liver relationship: RO:0002226 UBERON:0001113 ! develops in lobe of liver relationship: RO:0002433 UBERON:0004647 ! contributes to morphology of liver lobule [Term] id: UBERON:0001282 name: intralobular bile duct namespace: uberon def: "The tubules located between the bile canaliculi and interlobular bile ducts near the outer edge of a classic liver lobule." [MGI:csmith, MP:0009499] synonym: "canal of Herring" EXACT [FMA:17545] synonym: "cholangiole" EXACT [FMA:17545] xref: FMA:17545 xref: MA:0002669 xref: NCIT:C32255 xref: SCTID:227002 xref: SCTID:269922006 xref: UMLS:C0227517 {source="ncithesaurus:Canal_of_Hering"} xref: Wikipedia:Canals_of_Hering is_a: UBERON:0003704 {source="FMA"} ! intrahepatic bile duct is_a: UBERON:0014716 ! interlobular duct relationship: BFO:0000050 UBERON:0001172 {source="FMA"} ! part of hepatic acinus relationship: BFO:0000050 UBERON:0004647 {source="FMA"} ! part of liver lobule relationship: BFO:0000051 CL:0000182 ! has part hepatocyte relationship: BFO:0000051 CL:1000488 ! has part cholangiocyte relationship: RO:0002433 UBERON:0004647 ! contributes to morphology of liver lobule [Term] id: UBERON:0001285 name: nephron namespace: uberon def: "The basic functional unit of the kidney. its chief function is to regulate the concentration of water and soluble substances like sodium salts by filtering the blood, reabsorbing what is needed and excreting the rest as urine. A nephron eliminates wastes from the body, regulates blood volume and blood pressure, controls levels of electrolytes and metabolites, and regulates blood pH. Its functions are vital to life and are regulated by the endocrine system by hormones such as antidiuretic hormone, aldosterone, and parathyroid hormone.[WP]." [PMID:9268568, Wikipedia:Nephron] xref: BTO:0000924 xref: CALOHA:TS-1312 xref: EMAPA:28491 xref: EMAPA:35592 xref: EV:0100384 xref: FMA:17640 xref: GAID:428 xref: MA:0000375 xref: MESH:D009399 xref: NCIT:C13048 xref: SCTID:361337001 xref: TAO:0002153 xref: UMLS:C0027713 {source="ncithesaurus:Nephron"} xref: Wikipedia:Nephron xref: ZFA:0005282 is_a: UBERON:0000064 ! organ part relationship: BFO:0000050 UBERON:0007684 {source="FMA"} ! part of uriniferous tubule relationship: RO:0002433 UBERON:0002113 ! contributes to morphology of kidney relationship: RO:0002495 UBERON:0010532 {source="Bgee:AN"} ! immediate transformation of primitive nephron property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png" xsd:anyURI [Term] id: UBERON:0001295 name: endometrium namespace: uberon def: "The glandular mucous membrane lining of the uterine cavity that is hormonally responsive during the estrous/menstrual cycle and during pregnancy." [MESH:A05.360.319.679.490, MGI:smb, MP:0004896] synonym: "tunica mucosa (endometrium)" EXACT [FMA:17742] synonym: "uterine endometrium" EXACT [BTO:0001422] xref: BTO:0001422 xref: CALOHA:TS-0276 xref: EFO:0000980 xref: EMAPA:29917 xref: EV:0100115 xref: FMA:17742 xref: GAID:377 xref: MA:0000390 xref: MAT:0000319 xref: MESH:D004717 xref: MIAA:0000319 xref: NCIT:C12313 xref: SCTID:278867007 xref: UMLS:C0014180 {source="ncithesaurus:Endometrium"} xref: VHOG:0001285 xref: Wikipedia:Endometrium is_a: UBERON:0019042 ! reproductive system mucosa intersection_of: UBERON:0000344 ! mucosa intersection_of: BFO:0000050 UBERON:0000995 ! part of uterus relationship: BFO:0000050 UBERON:0000459 {source="FMA"} ! part of uterine wall relationship: RO:0002160 NCBITaxon:40674 ! only in taxon Mammalia relationship: RO:0002433 UBERON:0000995 ! contributes to morphology of uterus property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/6/66/Illu_cervix.jpg" xsd:anyURI [Term] id: UBERON:0001297 name: serosa of uterus namespace: uberon def: "Outer serosa layer of the uterus." [Wikipedia:Perimetrium] synonym: "perimetrium" EXACT [Wikipedia:Perimetrium] synonym: "serous coat of uterus" EXACT [Wikipedia:Perimetrium] synonym: "serous membrane of uterus" EXACT [OBOL:automatic] synonym: "tunica serosa (perimetrium)" EXACT [] synonym: "uterine serosa" EXACT [] synonym: "uterus serosa" EXACT [] synonym: "uterus serous membrane" EXACT [OBOL:automatic] synonym: "visceral peritoneum of uterus" EXACT [] xref: EMAPA:37792 {source="MA:th"} xref: FMA:17744 xref: MA:0001729 xref: NCIT:C33298 xref: SCTID:253705006 xref: UMLS:C0227824 {source="ncithesaurus:Perimetrium"} xref: Wikipedia:Perimetrium is_a: UBERON:0000042 ! serous membrane is_a: UBERON:0005156 ! reproductive structure intersection_of: UBERON:0000042 ! serous membrane intersection_of: BFO:0000050 UBERON:0000995 ! part of uterus relationship: BFO:0000050 UBERON:0000459 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! part of uterine wall property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/6/66/Illu_cervix.jpg" xsd:anyURI [Term] id: UBERON:0001299 name: glans penis namespace: uberon def: "The conic expansion of the corpus spongiosum that forms the head of the penis." [MGI:anna, MP:0009102] xref: BTO:0003118 xref: EMAPA:18988 xref: EV:0100108 xref: FMA:18247 xref: GAID:0000012 xref: MA:0002726 xref: NCIT:C12324 xref: SCTID:263378009 xref: UMLS:C0227948 {source="ncithesaurus:Glans_Penis"} xref: VHOG:0001475 xref: Wikipedia:Glans_penis is_a: UBERON:0035651 ! glans intersection_of: UBERON:0035651 ! glans intersection_of: BFO:0000050 UBERON:0000989 ! part of penis relationship: BFO:0000050 UBERON:0000989 ! part of penis relationship: RO:0002433 UBERON:0000989 ! contributes to morphology of penis relationship: RO:0002495 UBERON:0013239 {source="Bgee:AN"} ! immediate transformation of future glans penis relationship: sexually_homologous_to UBERON:0006653 ! glans clitoris property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/1/13/Anteriorglanspenis.jpg" xsd:anyURI property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/3/35/Male_anatomy.png" xsd:anyURI [Term] id: UBERON:0001301 name: epididymis namespace: uberon def: "The elongated structure connected to the posterior surface of the testis that transports, stores, and matures spermatozoa between testis and vas deferens." [MGI:pvb, MP:0002631] xref: BTO:0000408 xref: CALOHA:TS-0285 xref: EFO:0000982 xref: EMAPA:19290 xref: EV:0100103 xref: FMA:18255 xref: GAID:397 xref: galen:Epididymis xref: MA:0000397 xref: MAT:0000130 xref: MESH:D004822 xref: MIAA:0000130 xref: NCIT:C12328 xref: SCTID:181432000 xref: UMLS:C0014533 {source="ncithesaurus:Epididymis"} xref: VHOG:0001265 xref: Wikipedia:Epididymis is_a: UBERON:0000025 ! tube is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005904 ! duct of male reproductive system relationship: BFO:0000050 UBERON:0006947 {source="FMA"} ! part of male genital duct relationship: channel_for CL:0000019 ! sperm relationship: channels_from UBERON:0006946 ! efferent duct relationship: channels_into UBERON:0001000 ! vas deferens relationship: RO:0002160 NCBITaxon:7742 ! only in taxon Vertebrata relationship: RO:0002202 UBERON:0003074 {source="Wikipedia"} ! develops from mesonephric duct relationship: RO:0002433 UBERON:0004054 ! contributes to morphology of internal male genitalia property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/c/c3/Illu_testis_surface.jpg" xsd:anyURI [Term] id: UBERON:0001302 name: right uterine tube namespace: uberon def: "A fallopian tube that is part of a right side of organism [Automatically generated definition]." [OBOL:automatic] synonym: "right fallopian tube" EXACT [] synonym: "right oviduct" EXACT [] xref: EMAPA:37369 {source="MA:th"} xref: FMA:18483 xref: MA:0001717 xref: NCIT:C33475 xref: SCTID:280106006 xref: UMLS:C0227900 {source="ncithesaurus:Right_Fallopian_Tube"} is_a: UBERON:0003889 ! fallopian tube intersection_of: UBERON:0003889 ! fallopian tube intersection_of: BSPO:0000121 UBERON:0000468 ! in right side of multicellular organism relationship: BSPO:0000121 UBERON:0000468 ! in right side of multicellular organism property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Fallopian_Tube_R.glb" xsd:anyURI [Term] id: UBERON:0001303 name: left uterine tube namespace: uberon def: "A fallopian tube that is part of a left side of organism [Automatically generated definition]." [OBOL:automatic] synonym: "left fallopian tube" EXACT [] synonym: "left oviduct" EXACT [] xref: EMAPA:37368 {source="MA:th"} xref: FMA:18484 xref: MA:0001716 xref: NCIT:C32959 xref: SCTID:280107002 xref: UMLS:C0227902 {source="ncithesaurus:Left_Fallopian_Tube"} is_a: UBERON:0003889 ! fallopian tube intersection_of: UBERON:0003889 ! fallopian tube intersection_of: BSPO:0000120 UBERON:0000468 ! in left side of multicellular organism relationship: BSPO:0000120 UBERON:0000468 ! in left side of multicellular organism property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Fallopian_Tube_L.glb" xsd:anyURI [Term] id: UBERON:0001310 name: umbilical artery namespace: uberon def: "The umbilical artery is a paired artery (with one for each half of the body) that is found in the abdominal and pelvic regions. In the fetus, it extends into the umbilical cord. [WP,unvetted]." [https://github.com/obophenotype/uberon/issues/328, Wikipedia:Umbilical_artery] xref: BTO:0000841 xref: CALOHA:TS-1077 xref: EHDAA:1026 xref: EHDAA:410 xref: EMAPA:16331 xref: EMAPA:16372 xref: FMA:18820 xref: GAID:516 xref: MA:0002072 xref: MESH:D014469 xref: NCIT:C33827 xref: RETIRED_EHDAA2:0002106 xref: SCTID:261404000 xref: UMLS:C0041632 {source="ncithesaurus:Umbilical_Artery"} xref: Wikipedia:Umbilical_artery is_a: UBERON:0001637 ! artery is_a: UBERON:0010260 ! umbilical blood vessel property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/e/ee/Gray502.png" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Placenta.glb" xsd:anyURI [Term] id: UBERON:0001312 name: superior vesical artery namespace: uberon def: "An artery that supplies blood to the upper urinary bladder." [http://orcid.org/0000-0002-6601-2165] xref: EMAPA:37123 {source="MA:th"} xref: FMA:18839 xref: MA:0002080 xref: NCIT:C52686 xref: SCTID:113268007 xref: UMLS:C0226376 {source="ncithesaurus:Superior_Vesical_Artery"} xref: Wikipedia:Superior_vesical_artery is_a: UBERON:0003468 ! ureteric segment of renal artery is_a: UBERON:0009027 ! vesical artery intersection_of: UBERON:0009027 ! vesical artery intersection_of: RO:0002178 UBERON:0000056 ! supplies ureter relationship: RO:0002252 UBERON:0001310 ! connecting branch of umbilical artery property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/0/02/Internal_iliac_branches.PNG" xsd:anyURI [Term] id: UBERON:0001317 name: internal iliac vein namespace: uberon def: "A vein that begins near the upper part of the greater sciatic foramen, passes upward behind and slightly medial to the hypogastric artery and, at the brim of the pelvis, joins with the external iliac to form the common iliac vein. [WP,unvetted]." [Wikipedia:Internal_iliac_vein] xref: EHDAA2:0000874 xref: EMAPA:37148 {source="MA:th"} xref: FMA:18884 xref: galen:InternalIliacVein xref: MA:0002139 xref: MA:0002145 xref: NCIT:C32847 xref: SCTID:181399007 xref: UMLS:C0226764 {source="ncithesaurus:Internal_Iliac_Vein"} xref: VHOG:0000749 xref: Wikipedia:Internal_iliac_vein is_a: UBERON:0005610 {source="MA"} ! iliac vein relationship: RO:0002170 UBERON:0001139 ! connected to common iliac vein relationship: RO:0002179 UBERON:0005179 ! drains pelvic region element property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/c/cb/Internaliliacv.png" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI [Term] id: UBERON:0001325 name: muscle of pelvis namespace: uberon def: "Muscle (organ) which is a part of the pelvis. Examples: levator ani,." [FMA:19086] synonym: "muscle organ of pelvis" EXACT [OBOL:automatic] synonym: "pelvic muscle" EXACT [FMA:19086] synonym: "pelvis muscle" EXACT [] synonym: "pelvis muscle organ" EXACT [OBOL:automatic] xref: EMAPA:18184 xref: EMAPA:37481 {source="MA:th"} xref: FMA:19086 xref: MA:0000534 is_a: UBERON:0003833 {source="MA"} ! abdominal segment muscle is_a: UBERON:0005179 ! pelvic region element intersection_of: UBERON:0014892 {source="FMAdef"} ! skeletal muscle organ, vertebrate intersection_of: BFO:0000050 UBERON:0002355 {source="FMAdef"} ! part of pelvic region of trunk [Term] id: UBERON:0001330 name: pampiniform plexus namespace: uberon def: "The pampiniform plexus is a network of many small veins found in the male spermatic cord. It is formed by the union of multiple spermatic veins from the back of the testis and tributaries from the epididymis. The veins of the plexus ascend along the cord in front of the ductus deferens. Below the subcutaneous inguinal ring they unite to form three or four veins, which pass along the inguinal canal, and, entering the abdomen through the abdominal inguinal ring, coalesce to form two veins. These again unite to form a single vein, the testicular vein, which opens on the right side into the inferior vena cava, at an acute angle, and on the left side into the left renal vein, at a right angle. The pampinoform plexus forms the chief mass of the cord. In addition to its function in venous return from the testes, the pampiniform plexus also plays a role in the temperature regulation of the testes. It acts as a heat exchanger, cooling blood in adjacent arteries. An abnormal enlargement of the pampiniform plexus is a medical condition called varicocele. [WP,unvetted]." [Wikipedia:Pampiniform_venous_plexus] synonym: "pampiniform venous plexus" EXACT [] synonym: "plexus of veins of fascia of prostate" EXACT [] synonym: "venous plexus of fascia of prostate" EXACT [] synonym: "venous plexus of fascia of prostate gland" EXACT [] xref: EMAPA:37385 {source="MA:th"} xref: FMA:19607 xref: MA:0001866 xref: SCTID:279661001 xref: Wikipedia:Pampiniform_venous_plexus is_a: UBERON:0001593 ! venous plexus relationship: BFO:0000050 RO:0002577 ! part of system relationship: RO:0001025 UBERON:0005352 ! located in spermatic cord relationship: RO:0002170 UBERON:0000442 ! connected to right testicular vein property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/a/af/Gray1147.png" xsd:anyURI [Term] id: UBERON:0001331 name: skin of penis namespace: uberon def: "A zone of skin that is part of a penis [Automatically generated definition]." [OBOL:automatic] synonym: "penile skin" EXACT [FMA:19638] synonym: "penis skin" EXACT [] synonym: "penis zone of skin" EXACT [OBOL:automatic] synonym: "zone of skin of penis" EXACT [OBOL:automatic] xref: EMAPA:35675 xref: FMA:19638 xref: MA:0002727 xref: SCTID:35900000 is_a: UBERON:0000014 ! zone of skin is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005156 ! reproductive structure intersection_of: UBERON:0000014 ! zone of skin intersection_of: BFO:0000050 UBERON:0000989 ! part of penis relationship: BFO:0000050 UBERON:0000989 ! part of penis relationship: RO:0002150 UBERON:0001085 ! continuous with skin of trunk [Term] id: UBERON:0001333 name: male urethra namespace: uberon def: "A urethra that is part of a male reproductive system." [http://orcid.org/0000-0002-6601-2165] xref: BTO:0004089 xref: EMAPA:18692 xref: FMA:19668 xref: MA:0002640 xref: NCIT:C33050 xref: SCTID:264085007 xref: UMLS:C0458452 {source="ncithesaurus:Male_Urethra"} xref: Wikipedia:Male_urethra is_a: UBERON:0000057 ! urethra intersection_of: UBERON:0000057 ! urethra intersection_of: BFO:0000050 UBERON:0003101 ! part of male organism relationship: BFO:0000050 UBERON:0003101 ! part of male organism property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Urethra.glb" xsd:anyURI property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/c/cb/Female_anatomy.png" xsd:anyURI [Term] id: UBERON:0001334 name: female urethra namespace: uberon def: "A urethra that is part of a female reproductive system." [http://orcid.org/0000-0002-6601-2165] xref: BTO:0004088 xref: EMAPA:28747 xref: FMA:19669 xref: MA:0002637 xref: NCIT:C32591 xref: SCTID:264469008 xref: UMLS:C0458485 {source="ncithesaurus:Female_Urethra"} xref: Wikipedia:Female_urethra is_a: UBERON:0000057 ! urethra intersection_of: UBERON:0000057 ! urethra intersection_of: BFO:0000050 UBERON:0003100 ! part of female organism relationship: BFO:0000050 UBERON:0003100 ! part of female organism property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/c/cb/Female_anatomy.png" xsd:anyURI [Term] id: UBERON:0001338 name: urethral gland namespace: uberon def: "Any of the numerous small mucous-secreting glands located in the wall of the male or female urethra that help protect the epithelium from the corrosive urine." [MP:anna] synonym: "gland of urethra" EXACT [OBOL:automatic] synonym: "urethra gland" EXACT [] synonym: "urethra gland (male or female)" EXACT [] synonym: "urethral mucuous gland" EXACT [] xref: EMAPA:37784 {source="MA:th"} xref: FMA:19683 xref: MA:0001688 xref: SCTID:279477005 is_a: UBERON:0000414 {source="MP"} ! mucous gland is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0002530 ! gland intersection_of: BFO:0000050 UBERON:0000057 ! part of urethra relationship: BFO:0000050 UBERON:0000057 ! part of urethra relationship: RO:0002160 NCBITaxon:40674 ! only in taxon Mammalia relationship: RO:0002433 UBERON:0000057 ! contributes to morphology of urethra [Term] id: UBERON:0001343 name: seminiferous tubule of testis namespace: uberon def: "The tubules in the testes where spermatogenesis occurs." [https://github.com/obophenotype/uberon/issues/1381, ISBN:0-683-40008-8, MGI:csmith, MP:0002216] synonym: "seminiferous cord" EXACT [EMAPA:18685] synonym: "seminiferous tubule" EXACT [] synonym: "testis - seminiferous tubule" EXACT [] synonym: "tubuli seminiferi" EXACT [] xref: AAO:0010399 xref: BTO:0001235 xref: CALOHA:TS-1239 xref: EFO:0001404 xref: EMAPA:18685 xref: EMAPA:31476 xref: EV:0100380 xref: FMA:19825 xref: GAID:400 xref: MA:0000412 xref: MAT:0000503 xref: MESH:D012671 xref: NCIT:C13047 xref: NCIT:C34293 xref: SCTID:279614002 xref: UMLS:C0036630 {source="ncithesaurus:Seminiferous_Tubule"} xref: UMLS:C1519236 {source="ncithesaurus:Seminiferous_Cord"} xref: VHOG:0001363 xref: Wikipedia:Seminiferous_tubule xref: XAO:0003088 is_a: UBERON:0000025 ! tube is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005904 ! duct of male reproductive system relationship: BFO:0000050 UBERON:0000473 ! part of testis relationship: BFO:0000067 GO:0007283 ! contains process spermatogenesis relationship: channel_for CL:0000019 ! sperm relationship: channels_into UBERON:0003959 {gci_filler="NCBITaxon:40674", gci_relation="BFO:0000050"} ! rete testis relationship: RO:0002202 UBERON:0005297 {source="Wikipedia"} ! develops from testis sex cord property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/4/49/Seminiferous_tubule_and_sperm_low_mag.jpg" xsd:anyURI property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/6/6a/Gray1145.png" xsd:anyURI [Term] id: UBERON:0001353 name: anal region namespace: uberon def: "The anus and surrounding regions. Encompasses both internal and external regions, where present." [https://orcid.org/0000-0002-6601-2165] xref: EFO:0000847 xref: EHDAA2:0000122 xref: EHDAA:2931 xref: EMAPA:16831 xref: MA:0000329 xref: MAT:0000042 xref: MIAA:0000042 xref: NCIT:C32069 xref: SCTID:362680001 xref: UMLS:C0230120 {source="ncithesaurus:Anal_Region"} xref: VHOG:0000395 xref: WBbt:0006919 is_a: UBERON:0000475 ! organism subdivision relationship: RO:0002131 UBERON:0006866 ! overlaps terminal part of digestive tract relationship: RO:0002254 UBERON:0000931 ! has developmental contribution from proctodeum property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/f/fb/Gray408.png" xsd:anyURI [Term] id: UBERON:0001366 name: parietal peritoneum namespace: uberon def: "The outer layer of peritoneum that is attached to the abdominal and pelvic walls." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Peritoneum#Types] synonym: "parietal serous membrane of peritoneum" EXACT [UBERON:cjm] xref: AAO:0010816 xref: EMAPA:16591 xref: FMA:21451 xref: SCTID:362700006 xref: TAO:0005131 xref: VHOG:0001527 xref: Wikipedia:Parietal_peritoneum xref: ZFA:0005131 is_a: UBERON:0022351 ! parietal serous membrane intersection_of: UBERON:0022351 ! parietal serous membrane intersection_of: BFO:0000050 UBERON:0002358 ! part of peritoneum relationship: BFO:0000050 RO:0002577 ! part of system relationship: BFO:0000050 UBERON:0002358 ! part of peritoneum relationship: RO:0002371 UBERON:0003697 ! attached to abdominal wall property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray1040.png" xsd:anyURI [Term] id: UBERON:0001415 name: skin of pelvis namespace: uberon def: "A zone of skin that is part of a pelvis [Automatically generated definition]." [OBOL:automatic] synonym: "pelvic skin" EXACT [] synonym: "pelvis skin" EXACT [] synonym: "pelvis zone of skin" EXACT [OBOL:automatic] synonym: "zone of skin of pelvis" EXACT [OBOL:automatic] xref: EMAPA:37282 {source="MA:th"} xref: FMA:22984 xref: MA:0000546 xref: SCTID:181517009 is_a: UBERON:0003836 ! abdominal segment skin intersection_of: UBERON:0000014 ! zone of skin intersection_of: BFO:0000050 UBERON:0002355 ! part of pelvic region of trunk relationship: BFO:0000050 UBERON:0002355 ! part of pelvic region of trunk [Term] id: UBERON:0001416 name: skin of abdomen namespace: uberon def: "A zone of skin that is part of an abdomen [Automatically generated definition]." [OBOL:automatic] synonym: "abdomen skin" EXACT [] synonym: "abdomen zone of skin" EXACT [OBOL:automatic] synonym: "abdominal skin" EXACT [] synonym: "skin of abdomen proper" EXACT [FMA:22988] synonym: "zone of skin of abdomen" EXACT [OBOL:automatic] xref: EFO:0000214 xref: FMA:22988 xref: FMA:23000 xref: MA:0000523 xref: NCIT:C52758 xref: SCTID:361707007 xref: UMLS:C0222166 {source="ncithesaurus:Abdominal_Skin"} is_a: UBERON:0003836 ! abdominal segment skin intersection_of: UBERON:0000014 ! zone of skin intersection_of: BFO:0000050 UBERON:0000916 ! part of abdomen relationship: BFO:0000050 UBERON:0000916 ! part of abdomen [Term] id: UBERON:0001417 name: skin of neck namespace: uberon def: "A zone of skin that is part of a neck [Automatically generated definition]." [OBOL:automatic] synonym: "neck (volume) zone of skin" EXACT [OBOL:automatic] synonym: "neck skin" EXACT [] synonym: "neck zone of skin" EXACT [OBOL:automatic] synonym: "zone of skin of neck" EXACT [OBOL:automatic] synonym: "zone of skin of neck (volume)" EXACT [OBOL:automatic] xref: EMAPA:37277 {source="MA:th"} xref: FMA:23021 xref: FMA:23022 xref: MA:0000590 xref: NCIT:C52756 xref: SCTID:361705004 xref: UMLS:C0205030 {source="ncithesaurus:Neck_Skin"} is_a: UBERON:0000014 ! zone of skin intersection_of: UBERON:0000014 ! zone of skin intersection_of: BFO:0000050 UBERON:0000974 ! part of neck relationship: BFO:0000050 UBERON:0000974 ! part of neck [Term] id: UBERON:0001418 name: skin of thorax namespace: uberon def: "A zone of skin that is part of a thorax [Automatically generated definition]." [OBOL:automatic] synonym: "thoracic skin" EXACT [] synonym: "thorax skin" EXACT [] synonym: "thorax zone of skin" EXACT [OBOL:automatic] synonym: "zone of skin of thorax" EXACT [OBOL:automatic] xref: EMAPA:37765 {source="MA:th"} xref: FMA:23028 xref: FMA:23029 xref: MA:0000564 xref: SCTID:281723000 is_a: UBERON:0001085 ! skin of trunk intersection_of: UBERON:0000014 ! zone of skin intersection_of: BFO:0000050 UBERON:0000915 ! part of thoracic segment of trunk relationship: BFO:0000050 UBERON:0000915 ! part of thoracic segment of trunk [Term] id: UBERON:0001421 name: pectoral girdle region namespace: uberon def: "An organism subdivision that includes the pectoral girdle skeleton and associated soft tissue. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc). Examples: There are only two instances in an organism, right and left pectoral girdle regions." [FMA:23217, https://orcid.org/0000-0002-6601-2165, UBERONREF:0000003] synonym: "girdle - pectoral" EXACT [] xref: EMAPA:37856 {source="MA:th"} xref: FMA:23217 xref: galen:ShoulderGirdle xref: SCTID:229759004 xref: VSAO:0000305 is_a: UBERON:0007823 ! appendage girdle region is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0007823 ! appendage girdle region intersection_of: BFO:0000050 UBERON:0010708 ! part of pectoral complex disjoint_from: UBERON:0007831 ! pectoral girdle skeleton relationship: BFO:0000050 UBERON:0010708 ! part of pectoral complex relationship: BSPO:0000126 UBERON:0000468 ! in lateral side of multicellular organism relationship: RO:0002551 UBERON:0007831 ! has skeleton pectoral girdle skeleton property_value: IAO:0000232 "this class describes the organism subdivision, NOT the skeleton within. See also: skeleton of pectoral girdle (UBERON:0007831)." xsd:string [Term] id: UBERON:0001434 name: skeletal system namespace: uberon def: "Anatomical system that is a multi-element, multi-tissue anatomical cluster that consists of the skeleton and the articular system." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, VSAO:0000027] synonym: "skeleton system" EXACT [] xref: AAO:0000566 xref: BTO:0001486 xref: CALOHA:TS-1320 xref: EFO:0000806 xref: EHDAA2:0003168 xref: EMAPA:35773 xref: FMA:23881 xref: MA:0000018 xref: NCIT:C12788 xref: TAO:0000434 xref: UMLS:C0037253 {source="ncithesaurus:Skeletal_System"} xref: VHOG:0001254 xref: VSAO:0000027 xref: XAO:0003060 xref: ZFA:0000434 is_a: UBERON:0011216 ! organ system subdivision intersection_of: UBERON:0011216 ! organ system subdivision intersection_of: BFO:0000051 UBERON:0004288 ! has part skeleton intersection_of: BFO:0000051 UBERON:0004770 ! has part articular system disjoint_from: UBERON:0001474 ! bone element disjoint_from: UBERON:0002204 ! musculoskeletal system disjoint_from: UBERON:0002294 ! biliary system disjoint_from: UBERON:0002330 ! exocrine system disjoint_from: UBERON:0002390 ! hematopoietic system disjoint_from: UBERON:0002405 ! immune system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:8450002 ! excretory system relationship: BFO:0000050 UBERON:0002204 ! part of musculoskeletal system relationship: BFO:0000051 UBERON:0004288 ! has part skeleton relationship: BFO:0000051 UBERON:0004770 ! has part articular system relationship: RO:0002492 UBERON:0000066 ! existence ends during fully formed stage [Term] id: UBERON:0001444 name: subdivision of head namespace: uberon synonym: "head subdivision" EXACT [] xref: FMA:24218 xref: SCTID:123852005 xref: XAO:0000040 is_a: UBERON:0000475 ! organism subdivision relationship: BFO:0000050 UBERON:0000033 ! part of head [Term] id: UBERON:0001456 name: face namespace: uberon def: "A subdivision of the head that has as parts the layers deep to the surface of the anterior surface, including the mouth, eyes, and nose (when present). In vertebrates, this includes the facial skeleton and structures superficial to the facial skeleton (cheeks, mouth, eyeballs, skin of face, etc)." [http://orcid.org/0000-0002-6601-2165] xref: BTO:0003369 xref: CALOHA:TS-2216 xref: EMAPA:32763 xref: FMA:24728 xref: GAID:64 xref: galen:Face xref: HAO:0000316 xref: MA:0002473 xref: MESH:D005145 xref: NCIT:C13071 xref: SCTID:302549007 xref: UMLS:C0015450 {source="ncithesaurus:Face"} xref: Wikipedia:Face is_a: UBERON:0001444 ! subdivision of head relationship: BFO:0000051 UBERON:0000018 {gci_filler="NCBITaxon:50557", gci_relation="BFO:0000050"} ! has part compound eye relationship: BFO:0000051 UBERON:0000165 ! has part mouth relationship: RO:0002433 UBERON:0000033 ! contributes to morphology of head relationship: RO:0002551 UBERON:0011156 {gci_filler="NCBITaxon:7742", gci_relation="BFO:0000050"} ! has skeleton facial skeleton property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/5/55/Mona_Lisa_headcrop.jpg" xsd:anyURI [Term] id: UBERON:0001458 name: skin of lip namespace: uberon def: "A zone of skin that is part of a lip [Automatically generated definition]." [OBOL:automatic] synonym: "lip skin" EXACT [] synonym: "lip zone of skin" EXACT [OBOL:automatic] synonym: "zone of skin of lip" EXACT [OBOL:automatic] xref: EMAPA:37643 {source="MA:th"} xref: FMA:24764 xref: MA:0001579 xref: NCIT:C12291 xref: SCTID:244092005 xref: UMLS:C0222101 {source="ncithesaurus:Skin_of_the_Lip"} is_a: UBERON:0000014 ! zone of skin intersection_of: UBERON:0000014 ! zone of skin intersection_of: BFO:0000050 UBERON:0001833 ! part of lip relationship: BFO:0000050 UBERON:0001833 ! part of lip [Term] id: UBERON:0001474 name: bone element namespace: uberon def: "Skeletal element that is composed of bone tissue." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, https://github.com/obophenotype/uberon/issues/277, PSPUB:0000170, VSAO:0000057] synonym: "bone organ" EXACT [FMA:5018] xref: AAO:0000047 xref: AEO:0000082 xref: BTO:0000140 xref: CALOHA:TS-0088 xref: EFO:0000298 xref: EHDAA2:0003082 xref: EMAPA:32782 xref: ENVO:00002039 xref: EV:0100140 xref: FMA:30317 xref: FMA:5018 xref: GAID:92 xref: galen:Bone xref: MA:0001459 xref: MAT:0000299 xref: MIAA:0000299 xref: NCIT:C12366 xref: SCTID:90780006 xref: TAO:0001514 xref: UMLS:C0262950 {source="ncithesaurus:Bone"} xref: VHOG:0001190 xref: VSAO:0000057 xref: Wikipedia:Bone xref: XAO:0000169 xref: ZFA:0001514 is_a: UBERON:0004765 ! skeletal element intersection_of: UBERON:0004765 ! skeletal element intersection_of: RO:0002473 UBERON:0002481 ! composed primarily of bone tissue disjoint_from: UBERON:0001630 ! muscle organ disjoint_from: UBERON:0005090 ! muscle structure relationship: RO:0002160 NCBITaxon:7742 ! only in taxon Vertebrata relationship: RO:0002473 UBERON:0002481 {source="VSAO-modified"} ! composed primarily of bone tissue [Term] id: UBERON:0001484 name: articular capsule namespace: uberon def: "An articular capsule (or joint capsule) is an envelope surrounding a synovial joint. [WP,unvetted]." [Wikipedia:Articular_capsule] synonym: "fibrous capsule of joint" EXACT [] synonym: "joint capsule" EXACT [] synonym: "joint fibrous capsule" EXACT [] xref: EMAPA:37621 {source="MA:th"} xref: FMA:34836 xref: GAID:263 xref: galen:JointCapsule xref: MA:0001519 xref: MESH:D017746 xref: NCIT:C32259 xref: NCIT:C84388 xref: SCTID:182238002 xref: UMLS:C0206207 {source="ncithesaurus:Joint_Capsule"} xref: Wikipedia:Articular_capsule is_a: UBERON:0000094 ! membrane organ intersection_of: UBERON:0000094 ! membrane organ intersection_of: BFO:0000051 UBERON:0007616 ! has part layer of synovial tissue intersection_of: RO:0002221 UBERON:0002217 ! surrounds synovial joint relationship: BFO:0000051 UBERON:0007616 ! has part layer of synovial tissue relationship: RO:0002221 UBERON:0002217 ! surrounds synovial joint property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/1/19/Joint.png" xsd:anyURI property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/4/4a/Gray299.png" xsd:anyURI [Term] id: UBERON:0001496 name: ascending aorta namespace: uberon def: "The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta[GO]. A portion of the aorta commencing at the upper part of the base of the left ventricle, on a level with the lower border of the third costal cartilage behind the left half of the sternum; it passes obliquely upward, forward, and to the right, in the direction of the heart's axis, as high as the upper border of the second right costal cartilage, describing a slight curve in its course, and being situated, about 6 cm behind the posterior surface of the sternum. The total length is about 5 cm in length [Wikipedia]." [GO:0035905, Wikipedia:Ascending_aorta] synonym: "ascending thoracic aorta" EXACT [EMAPA:17014] synonym: "pars ascendens aortae" EXACT [] xref: EHDAA2:0000147 xref: EHDAA:9828 xref: EMAPA:17014 xref: FMA:3736 xref: MA:0002570 xref: NCIT:C32150 xref: SCTID:181299009 xref: UMLS:C0003956 {source="ncithesaurus:Ascending_Aorta"} xref: Wikipedia:Ascending_aorta is_a: UBERON:0001515 ! thoracic aorta relationship: BFO:0000050 UBERON:0001515 ! part of thoracic aorta relationship: RO:0002202 UBERON:0005338 {source="EHDAA2"} ! develops from outflow tract aortic component relationship: RO:0002254 UBERON:0002061 ! has developmental contribution from truncus arteriosus relationship: RO:0002254 UBERON:0005432 ! has developmental contribution from aortic sac relationship: RO:0002433 UBERON:0001515 ! contributes to morphology of thoracic aorta property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/e/e6/Gray506.svg" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI [Term] id: UBERON:0001497 name: muscle of pelvic girdle namespace: uberon def: "Any muscle organ that is part of a pelvic girdle [Automatically generated definition]." [OBOL:automatic] synonym: "girdle-pelvic muscle organ" EXACT [OBOL:automatic] synonym: "muscle organ of girdle-pelvic" EXACT [OBOL:automatic] synonym: "muscle organ of pelvic girdle" EXACT [OBOL:automatic] synonym: "muscle organ of pelvic girdle bone" EXACT [OBOL:automatic] synonym: "pelvic girdle muscle" EXACT [] synonym: "pelvic girdle muscle organ" EXACT [OBOL:automatic] synonym: "pelvic girdle skeletal muscle" EXACT [EMAPA:18185] xref: EHDAA:8326 xref: EMAPA:18184 xref: EMAPA:18185 xref: FMA:37367 xref: MA:0000537 xref: RETIRED_EHDAA2:0001430 is_a: UBERON:0001325 ! muscle of pelvis is_a: UBERON:0010890 ! pelvic complex muscle intersection_of: UBERON:0014892 ! skeletal muscle organ, vertebrate intersection_of: BFO:0000050 UBERON:0001271 ! part of pelvic girdle region relationship: BFO:0000050 UBERON:0004470 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! part of musculature of pelvic girdle [Term] id: UBERON:0001508 name: arch of aorta namespace: uberon def: "The convex portion of the aorta between the ascending and descending parts of the aorta; branches from it include the brachiocephalic trunk, the left common carotid artery, and the left subclavian artery; the brachiocephalic trunk further splits to form the right subclavian artery and the right common carotid artery." [ISBN:0-683-40008-8, MP:0004113] xref: BTO:0000157 xref: EFO:0002526 xref: EHDAA2:0000132 xref: EMAPA:17613 xref: FMA:3768 xref: GAID:471 xref: MA:0000475 xref: SCTID:181300001 xref: VHOG:0001196 xref: Wikipedia:Arch_of_aorta is_a: UBERON:0001515 ! thoracic aorta relationship: BFO:0000050 UBERON:0001515 ! part of thoracic aorta relationship: RO:0002170 UBERON:0001496 ! connected to ascending aorta relationship: RO:0002202 UBERON:0003121 ! develops from pharyngeal arch artery 4 relationship: RO:0002254 UBERON:0005432 ! has developmental contribution from aortic sac relationship: RO:0002254 UBERON:0005613 ! has developmental contribution from left dorsal aorta relationship: RO:0002433 UBERON:0001515 ! contributes to morphology of thoracic aorta property_value: IAO:0000232 "Do not confuse with aortic arch" xsd:string property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/e/e6/Gray506.svg" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI [Term] id: UBERON:0001514 name: descending aorta namespace: uberon def: "The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries[GO]. The descending aorta is part of the aorta, the largest artery in the body. The descending aorta is the part of the aorta beginning at the aortic arch that runs down through the chest and abdomen. The descending aorta is divided into two portions, the thoracic and abdominal, in correspondence with the two great cavities of the trunk in which it is situated. Within the abdomen, the descending aorta branches into the two common iliac arteries which serve the legs. [WP,unvetted]." [GO:0035906, Wikipedia:Descending_aorta] synonym: "pars descendens aortae" EXACT [FMA:3784] xref: EMAPA:18606 xref: FMA:3784 xref: MA:0002571 xref: NCIT:C32455 xref: SCTID:261399002 xref: UMLS:C0011666 {source="ncithesaurus:Descending_Aorta"} xref: Wikipedia:Descending_aorta is_a: UBERON:0005800 {source="FMA"} ! section of aorta relationship: RO:0002170 UBERON:0001508 ! connected to arch of aorta relationship: RO:0002202 UBERON:0005805 {source="Wikipedia"} ! develops from dorsal aorta relationship: RO:0002254 UBERON:0005613 ! has developmental contribution from left dorsal aorta relationship: RO:0002254 UBERON:0005622 ! has developmental contribution from right dorsal aorta property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/e/e6/Gray506.svg" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI [Term] id: UBERON:0001515 name: thoracic aorta namespace: uberon def: "The part of the aorta that extends from the origin at the heart to the diaphragm, and from which arises numerous branches that supply oxygenated blood to the chest cage and the organs within the chest." [http://www.medterms.com, MP:0010468] synonym: "thoracic part of aorta" EXACT [] xref: BTO:0000157 xref: EFO:0002525 xref: EMAPA:18603 xref: FMA:3786 xref: GAID:471 xref: galen:ThoracicAorta xref: MA:0002569 xref: MESH:D001013 xref: NCIT:C33766 xref: SCTID:302510009 xref: UMLS:C1522460 {source="ncithesaurus:Thoracic_Aorta"} xref: Wikipedia:Thoracic_aorta is_a: UBERON:0005800 {source="FMA"} ! section of aorta intersection_of: UBERON:0005800 ! section of aorta intersection_of: BFO:0000050 UBERON:0000915 ! part of thoracic segment of trunk relationship: BFO:0000050 UBERON:0000915 ! part of thoracic segment of trunk relationship: RO:0002433 UBERON:0000947 ! contributes to morphology of aorta property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/7/75/Gray530.png" xsd:anyURI [Term] id: UBERON:0001516 name: abdominal aorta namespace: uberon def: "Abdominal part of aorta: the distal part of the descending aorta, which is the continuation of the thoracic part and gives rise to the inferior phrenic, lumbar, median sacral, superior and inferior mesenteric, middle suprarenal, renal, and testicular or ovarian arteries, and celiac trunk[BTO]. The abdominal aorta is the largest artery in the abdominal cavity. As part of the aorta, it is a direct continuation of descending aorta(of the thorax). [WP,unvetted]." [BTO:0002976, Wikipedia:Abdominal_aorta] synonym: "abdominal part of aorta" EXACT [FMA:3789] synonym: "descending abdominal aorta" EXACT [FMA:3789] synonym: "pars abdominalis aortae" EXACT [FMA:3789] xref: BTO:0002976 xref: EFO:0002524 xref: EMAPA:17856 xref: FMA:3789 xref: GAID:470 xref: galen:AbdominalAorta xref: MA:0000474 xref: MESH:D001012 xref: NCIT:C32038 xref: SCTID:244231007 xref: UMLS:C0003484 {source="ncithesaurus:Abdominal_Aorta"} xref: Wikipedia:Abdominal_aorta is_a: UBERON:0005800 ! section of aorta relationship: BFO:0000050 UBERON:0001514 {source="FMA"} ! part of descending aorta relationship: RO:0002131 UBERON:0000916 ! overlaps abdomen relationship: RO:0002170 UBERON:0002345 ! connected to descending thoracic aorta relationship: RO:0002433 UBERON:0001514 ! contributes to morphology of descending aorta property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/a/af/Gray531.png" xsd:anyURI [Term] id: UBERON:0001529 name: brachiocephalic artery namespace: uberon def: "The short first aortic arch branch and divides into the right subclavian artery and the right common carotid artery." [MGI:csmith, MP:0010663] synonym: "brachiocephalic trunk" EXACT [MA:0001922] synonym: "innominate artery" EXACT [Wikipedia:Brachiocephalic_artery] xref: EFO:0002550 xref: EHDAA2:0000835 xref: EMAPA:17615 xref: FMA:3932 xref: GAID:476 xref: galen:BrachioCephalicArtery xref: MA:0001922 xref: MESH:D016122 xref: NCIT:C32814 xref: SCTID:244244002 xref: UMLS:C0006094 {source="ncithesaurus:Innominate_Artery"} xref: Wikipedia:Brachiocephalic_artery is_a: UBERON:0004573 ! systemic artery relationship: BFO:0000050 RO:0002577 ! part of system relationship: BFO:0000050 UBERON:0007204 ! part of brachiocephalic vasculature relationship: channels_from UBERON:0001508 ! arch of aorta relationship: RO:0002170 UBERON:0001508 ! connected to arch of aorta property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/e/e6/Gray506.svg" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI [Term] id: UBERON:0001530 name: common carotid artery plus branches namespace: uberon def: "A bilaterally paired branched artery that originates from the aortic arches and divides into and includes as parts the internal and external carotid arteries[cjm]." [Wikipedia:Common_carotid_artery] synonym: "carotid artery system" EXACT [EHDAA2:0000217] synonym: "trunk of common carotid tree" EXACT [FMA:3939] xref: CALOHA:TS-0116 xref: EHDAA2:0000217 xref: EHDAA:7331 xref: EMAPA:17855 xref: FMA:3939 xref: GAID:479 xref: MA:0001926 xref: MESH:D017536 xref: NCIT:C32352 xref: SCTID:362041005 xref: UMLS:C0162859 {source="ncithesaurus:Common_Carotid_Artery"} xref: VHOG:0000272 xref: Wikipedia:Common_carotid_artery is_a: UBERON:0004573 {source="FMA"} ! systemic artery relationship: BFO:0000050 RO:0002577 ! part of system relationship: RO:0002170 UBERON:0001508 ! connected to arch of aorta relationship: RO:0002202 UBERON:0004363 {source="Wikipedia"} ! develops from pharyngeal arch artery relationship: RO:0002488 UBERON:0000068 ! existence starts during embryo stage property_value: IAO:0000232 "This class represents the adult and developing structures'" xsd:string property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/e/e6/Gray506.svg" xsd:anyURI [Term] id: UBERON:0001533 name: subclavian artery namespace: uberon def: "One of two laterally paired arteries that supplies the pectoral appendages, usually branching from the dorsal aorta." [https://orcid.org/0000-0002-6601-2165, ISBN:0073040584] synonym: "arterial tree of upper limb" EXACT [] synonym: "pectoral artery" EXACT [] synonym: "subclavian arterial tree" EXACT [] xref: AAO:0010232 xref: EHDAA2:0001933 xref: EHDAA:4357 xref: EMAPA:17617 xref: FMA:3951 xref: GAID:511 xref: MA:0002045 xref: MESH:D013348 xref: NCIT:C33643 xref: SCTID:265790007 xref: TAO:0005086 xref: UMLS:C0038530 {source="ncithesaurus:Subclavian_Artery"} xref: Wikipedia:Subclavian_artery xref: XAO:0000365 xref: ZFA:0005086 is_a: UBERON:0004573 ! systemic artery relationship: BFO:0000050 RO:0002577 ! part of system relationship: RO:0002131 UBERON:0000915 ! overlaps thoracic segment of trunk relationship: RO:0002170 UBERON:0001508 ! connected to arch of aorta relationship: RO:0002178 UBERON:0004710 ! supplies pectoral appendage relationship: RO:0002202 UBERON:0002457 {source="EHDAA2"} ! develops from intersomitic artery relationship: RO:0002202 UBERON:0005622 {source="EHDAA2"} ! develops from right dorsal aorta property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/e/e6/Gray506.svg" xsd:anyURI [Term] id: UBERON:0001534 name: right subclavian artery namespace: uberon def: "The subclavian artery that supplies the right pectoral appendage." [http://orcid.org/0000-0002-6601-2165] xref: EHDAA2:0004514 xref: EMAPA:37384 {source="MA:th"} xref: FMA:3953 xref: MA:0002047 xref: NCIT:C33490 xref: SCTID:244246000 xref: UMLS:C0226261 {source="ncithesaurus:Right_Subclavian_Artery"} xref: Wikipedia:Subclavian_artery is_a: UBERON:0001533 ! subclavian artery is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0001533 ! subclavian artery intersection_of: BSPO:0000121 UBERON:0000468 ! in right side of multicellular organism relationship: BSPO:0000121 UBERON:0000468 ! in right side of multicellular organism relationship: RO:0002170 UBERON:0001529 ! connected to brachiocephalic artery relationship: RO:0002380 UBERON:0001529 {gci_filler="NCBITaxon:40674", gci_relation="BFO:0000050", source="FMA"} ! branching part of brachiocephalic artery property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/e/e6/Gray506.svg" xsd:anyURI [Term] id: UBERON:0001555 name: digestive tract namespace: uberon def: "A tube extending from the mouth to the anus." [https://github.com/geneontology/go-ontology/issues/7549, Wikipedia:Talk\:Human_gastrointestinal_tract] synonym: "digestive tube" EXACT [] synonym: "enteric tract" EXACT [ZFA:0000112] xref: AAO:0010023 xref: BILA:0000083 xref: BTO:0000511 xref: BTO:0000545 xref: EHDAA2:0000726 xref: EHDAA:518 xref: EMAPA:16247 xref: FMA:45615 xref: galen:AlimentaryTract xref: MA:0000917 xref: NCIT:C34082 xref: TAO:0000112 xref: TGMA:0001819 xref: UMLS:C0017189 {source="ncithesaurus:Gastrointestinal_Tract"} xref: VHOG:0000309 xref: WBbt:0005743 xref: ZFA:0000112 is_a: UBERON:0000025 ! tube relationship: BFO:0000050 UBERON:0001007 ! part of digestive system relationship: RO:0002160 NCBITaxon:6072 ! only in taxon Eumetazoa relationship: RO:0002176 UBERON:0000165 ! connects mouth relationship: RO:0002495 UBERON:0007026 {source="NCBIBook:NBK10107"} ! immediate transformation of presumptive gut [Term] id: UBERON:0001556 name: lower urinary tract namespace: uberon def: "Subdivision of urinary system which consists of the urinary bladder and the urethra." [FMA:45659] xref: FMA:45659 xref: galen:LowerUrinaryTract xref: MA:0002636 xref: SCTID:181420004 is_a: UBERON:0011216 ! organ system subdivision relationship: BFO:0000050 UBERON:0001008 ! part of renal system relationship: BFO:0000051 UBERON:0000057 ! has part urethra relationship: BFO:0000051 UBERON:0001255 ! has part urinary bladder [Term] id: UBERON:0001558 name: lower respiratory tract namespace: uberon def: "The segment of the respiratory tract that starts proximally with the trachea and includes all distal structures including the lungs[WP,modified]." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Lower_respiratory_tract] synonym: "lower respiratory system" EXACT [] xref: EHDAA2:0001036 xref: EMAPA:16738 xref: FMA:45662 xref: MA:0000435 xref: SCTID:281488008 xref: VHOG:0000382 xref: Wikipedia:Lower_respiratory_tract is_a: UBERON:0000072 ! proximo-distal subdivision of respiratory tract relationship: BFO:0000051 UBERON:0000170 ! has part pair of lungs property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/9/9f/Illu_conducting_passages.svg" xsd:anyURI property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/c/c3/Illu_conducting_passages.jpg" xsd:anyURI [Term] id: UBERON:0001584 name: left subclavian artery namespace: uberon def: "The subclavian artery that supplies the left pectoral appendage." [http://orcid.org/0000-0002-6601-2165] xref: EMAPA:37100 {source="MA:th"} xref: FMA:4694 xref: MA:0002046 xref: NCIT:C32972 xref: SCTID:244245001 xref: UMLS:C0226262 {source="ncithesaurus:Left_Subclavian_Artery"} xref: Wikipedia:Subclavian_artery is_a: UBERON:0001533 ! subclavian artery is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0001533 ! subclavian artery intersection_of: BSPO:0000120 UBERON:0000468 ! in left side of multicellular organism relationship: BSPO:0000120 UBERON:0000468 ! in left side of multicellular organism relationship: channels_from UBERON:0001508 ! arch of aorta property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/e/e6/Gray506.svg" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI [Term] id: UBERON:0001585 name: anterior vena cava namespace: uberon def: "A vein that carries deoxygenated blood from the upper half of the body into the right atrium of the heart." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Superior_vena_cava] synonym: "superior caval vein" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "superior vena cava" EXACT [FMA:4720] xref: BTO:0002683 xref: EHDAA2:0001962 xref: EHDAA:8726 xref: EMAPA:18417 xref: FMA:4720 xref: GAID:549 xref: galen:SuperiorVenaCava xref: MA:0000481 xref: MESH:D014683 xref: NCIT:C12816 xref: SCTID:181368006 xref: UMLS:C0042459 {source="ncithesaurus:Superior_Vena_Cava"} xref: VHOG:0001195 xref: Wikipedia:Superior_vena_cava is_a: UBERON:0004087 ! vena cava intersection_of: UBERON:0004087 ! vena cava intersection_of: RO:0002179 UBERON:0000153 ! drains anterior region of body relationship: BFO:0000050 RO:0002577 ! part of system relationship: RO:0002170 UBERON:0002078 ! connected to right cardiac atrium relationship: RO:0002179 UBERON:0000153 ! drains anterior region of body property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/b/b4/Venenwinkel.png" xsd:anyURI [Term] id: UBERON:0001586 name: internal jugular vein namespace: uberon def: "One of two jugular veins that collect the blood from the brain, the superficial parts of the face, and the neck. [WP,unvetted]." [Wikipedia:Internal_jugular_vein] synonym: "internal jugular" EXACT [EHDAA2:0000877] synonym: "internal jugular venous tree" EXACT [] xref: AAO:0010236 xref: EHDAA2:0000877 xref: EHDAA:5407 xref: EMAPA:17620 xref: FMA:4724 xref: galen:InternalJugularVein xref: MA:0002157 xref: NCIT:C32849 xref: RETIRED_EHDAA2:0000878 xref: SCTID:181372005 xref: UMLS:C0226550 {source="ncithesaurus:Internal_Jugular_Vein"} xref: Wikipedia:Internal_jugular_vein xref: XAO:0000382 is_a: UBERON:0004711 ! jugular vein relationship: RO:0002170 UBERON:0003711 ! connected to brachiocephalic vein relationship: RO:0002179 UBERON:0000955 ! drains brain relationship: RO:0002179 UBERON:0001456 ! drains face property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/e/e9/Gray562.png" xsd:anyURI [Term] id: UBERON:0001593 name: venous plexus namespace: uberon def: "A congregation of multiple veins." [Wikipedia:Venous_plexus] synonym: "venous network" EXACT [] xref: EMAPA:36327 xref: FMA:4767 xref: MA:0000069 xref: SCTID:322151008 xref: Wikipedia:Venous_plexus is_a: UBERON:0004537 ! blood vasculature is_a: UBERON:0005629 ! vascular plexus intersection_of: UBERON:0005629 ! vascular plexus intersection_of: RO:0002473 UBERON:0001638 ! composed primarily of vein relationship: RO:0002473 UBERON:0001638 ! composed primarily of vein property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/b/bd/Gray585.png" xsd:anyURI [Term] id: UBERON:0001605 name: ciliary muscle namespace: uberon def: "The ciliary muscle is a ring of smooth muscle in the middle layer of the eye that controls the eye's accommodation for viewing objects at varying distances and regulates the flow of aqueous humour through Schlemm's canal. [WP,unvetted]." [Wikipedia:Ciliary_muscle] synonym: "musculus ciliarus" EXACT [BTO:0000654] xref: BTO:0000654 xref: EMAPA:35240 xref: FMA:49151 xref: MA:0001269 xref: NCIT:C32315 xref: SCTID:280862009 xref: UMLS:C0559230 {source="ncithesaurus:Ciliary_Muscle"} xref: Wikipedia:Ciliary_muscle is_a: UBERON:0003386 {source="MA"} ! smooth muscle of eye is_a: UBERON:0010314 ! structure with developmental contribution from neural crest is_a: UBERON:0011222 {source="FMA"} ! intra-ocular muscle relationship: BFO:0000050 UBERON:0001775 {source="FMA"} ! part of ciliary body property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/2/28/Gray872.png" xsd:anyURI [Term] id: UBERON:0001606 name: muscle of iris namespace: uberon synonym: "iris muscle" EXACT [] synonym: "iris muscle organ" EXACT [OBOL:automatic] synonym: "muscle organ of iris" EXACT [OBOL:automatic] xref: EMAPA:35448 xref: FMA:49154 xref: MA:0001287 xref: SCTID:280888007 xref: Wikipedia:Iris_muscle is_a: UBERON:0011222 {source="FMA"} ! intra-ocular muscle intersection_of: UBERON:0001630 ! muscle organ intersection_of: BFO:0000050 UBERON:0001769 ! part of iris relationship: BFO:0000050 UBERON:0001769 ! part of iris [Term] id: UBERON:0001607 name: sphincter pupillae namespace: uberon def: "A sphincter muscle that is part of the iris." [Wikipedia:Iris_sphincter_muscle] synonym: "iris sphincter muscle" EXACT [BTO:0000656] synonym: "M. sphincter pupillae" EXACT [] synonym: "musculus sphincter pupillae" EXACT [BTO:0000656] synonym: "sphincter muscle of pupil" EXACT [BTO:0000656] xref: BTO:0000656 xref: EMAPA:35788 xref: FMA:49157 xref: MA:0001289 xref: NCIT:C33586 xref: SCTID:280889004 xref: UMLS:C0229189 {source="ncithesaurus:Sphincter_Pupillae_Muscle"} xref: Wikipedia:Iris_sphincter_muscle is_a: UBERON:0001606 ! muscle of iris is_a: UBERON:0004234 {source="BTO"} ! iris smooth muscle is_a: UBERON:0007521 ! smooth muscle sphincter intersection_of: UBERON:0004590 ! sphincter muscle intersection_of: BFO:0000050 UBERON:0001769 ! part of iris relationship: BFO:0000050 RO:0002577 ! part of system relationship: RO:0002202 UBERON:0002346 {source="ISBN:0781772214"} ! develops from neurectoderm relationship: RO:0002372 UBERON:0001769 ! has muscle origin iris relationship: RO:0002373 UBERON:0001769 ! has muscle insertion iris relationship: RO:0002568 UBERON:0001608 {source="dbpedia"} ! has muscle antagonist dilatator pupillae property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/2/2f/Gray878.png" xsd:anyURI [Term] id: UBERON:0001608 name: dilatator pupillae namespace: uberon def: "A smooth muscle of the eye, running radially in the iris that functions as a dilator. [WP,unvetted]." [Wikipedia:Iris_dilator_muscle] synonym: "dilator muscle of pupil" EXACT [] synonym: "dilator of pupil" EXACT [] synonym: "dilator pupillae" EXACT [] synonym: "dilator pupillae muscle" EXACT [Wikipedia:Iris_dilator_muscle] synonym: "iris dilator muscle" EXACT [BTO:0001371] synonym: "pupillary dilator muscle" EXACT [Wikipedia:Iris_dilator_muscle] synonym: "radial muscle of iris" EXACT [Wikipedia:Iris_dilator_muscle] xref: BTO:0001371 xref: EMAPA:35286 xref: FMA:49158 xref: MA:0001288 xref: NCIT:C32463 xref: SCTID:280890008 xref: UMLS:C0229190 {source="ncithesaurus:Dilator_Pupillae_Muscle"} xref: Wikipedia:Iris_dilator_muscle is_a: UBERON:0004234 {source="BTO"} ! iris smooth muscle relationship: BFO:0000050 RO:0002577 ! part of system relationship: RO:0002202 UBERON:0002346 {source="ISBN:0781772214"} ! develops from neurectoderm relationship: RO:0002372 UBERON:0001769 ! has muscle origin iris relationship: RO:0002373 UBERON:0001769 ! has muscle insertion iris relationship: RO:0002568 UBERON:0001607 {source="dbpedia"} ! has muscle antagonist sphincter pupillae property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/2/2f/Gray878.png" xsd:anyURI [Term] id: UBERON:0001612 name: facial artery namespace: uberon def: "A branch of the external carotid artery that supplies structures of the face. [WP,unvetted]." [Wikipedia:Facial_artery] xref: EMAPA:19213 xref: FMA:49549 xref: MA:0001950 xref: NCIT:C32578 xref: SCTID:181328007 xref: UMLS:C0226109 {source="ncithesaurus:Facial_Artery"} xref: Wikipedia:Facial_artery is_a: UBERON:0035398 ! branch of external carotid artery intersection_of: UBERON:0001637 ! artery intersection_of: RO:0002178 UBERON:0001456 ! supplies face intersection_of: RO:0002252 UBERON:0001070 ! connecting branch of external carotid artery relationship: RO:0002178 UBERON:0001456 ! supplies face property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/7/7b/Gray508.png" xsd:anyURI [Term] id: UBERON:0001616 name: maxillary artery namespace: uberon def: "An artery that supplies deep structures of the face. It comes just out behind the neck of the mandible. [WP,unvetted]." [Wikipedia:Maxillary_artery] xref: EHDAA2:0001069 xref: EHDAA:7357 xref: EMAPA:17311 xref: FMA:49675 xref: GAID:498 xref: MA:0001919 xref: MESH:D008438 xref: NCIT:C34205 xref: SCTID:181326006 xref: UMLS:C0024949 {source="ncithesaurus:Maxillary_Artery"} xref: Wikipedia:Maxillary_artery is_a: UBERON:0001637 ! artery intersection_of: UBERON:0001637 ! artery intersection_of: RO:0002207 UBERON:0003118 ! directly develops from pharyngeal arch artery 1 relationship: BFO:0000050 RO:0002577 ! part of system relationship: RO:0002170 UBERON:0001070 ! connected to external carotid artery relationship: RO:0002207 UBERON:0003118 ! directly develops from pharyngeal arch artery 1 property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/3/39/Gray510.png" xsd:anyURI [Term] id: UBERON:0001630 name: muscle organ namespace: uberon def: "Organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work[GO]." [GO:0007517] xref: AAO:0011066 xref: EMAPA:32715 xref: EMAPA:37474 {source="MA:th"} xref: EV:0100146 xref: FMA:5022 xref: GAID:131 xref: galen:Muscle xref: MA:0000015 xref: SCTID:71616004 xref: TAO:0005145 xref: VHOG:0001245 xref: XAO:0000172 xref: ZFA:0005145 is_a: UBERON:0000062 ! organ is_a: UBERON:0005090 ! muscle structure intersection_of: UBERON:0000062 ! organ intersection_of: RO:0002473 UBERON:0002385 ! composed primarily of muscle tissue relationship: BFO:0000050 UBERON:0001015 ! part of musculature relationship: RO:0002473 UBERON:0002385 ! composed primarily of muscle tissue [Term] id: UBERON:0001637 name: artery namespace: uberon def: "An epithelial tube or tree of tibes that transports blood away from the heart[modified from AEO definition]." [AEO:JB] synonym: "arterial subtree" EXACT [] synonym: "arterial tree organ part" EXACT [] xref: AAO:0010211 xref: AEO:0000208 xref: BTO:0000573 xref: CALOHA:TS-0054 xref: EFO:0000814 xref: EHDAA2:0000143 xref: EHDAA2:0003253 xref: EMAPA:35147 xref: EV:0100026 xref: FMA:50720 xref: GAID:468 xref: galen:Artery xref: MA:0000064 xref: MAT:0000034 xref: MESH:D001158 xref: MIAA:0000034 xref: NCIT:C12372 xref: SCTID:362877004 xref: TAO:0000005 xref: UMLS:C0003842 {source="ncithesaurus:Artery"} xref: VHOG:0001251 xref: Wikipedia:Artery xref: XAO:0000114 xref: ZFA:0000005 is_a: UBERON:0003509 ! arterial blood vessel relationship: channels_from UBERON:0000948 ! heart [Term] id: UBERON:0001638 name: vein namespace: uberon def: "Any of the tubular branching vessels that carry blood from the capillaries toward the heart." [Wikipedia:Vein] synonym: "venous tree organ part" EXACT [] xref: AAO:0010212 xref: AEO:0000209 xref: BTO:0000234 xref: CALOHA:TS-1108 xref: EFO:0000816 xref: EHDAA2:0003254 xref: EMAPA:35906 xref: EV:0100031 xref: FMA:50723 xref: GAID:492 xref: galen:Vein xref: MA:0000067 xref: MAT:0000037 xref: MESH:D014680 xref: MIAA:0000037 xref: NCIT:C12814 xref: SCTID:181367001 xref: TAO:0000082 xref: UMLS:C0042449 {source="ncithesaurus:Vein"} xref: VHOG:0001743 xref: Wikipedia:Vein xref: XAO:0000115 xref: ZFA:0000082 is_a: UBERON:0003920 ! venous blood vessel intersection_of: UBERON:0003920 ! venous blood vessel intersection_of: channel_for UBERON:0013756 ! venous blood relationship: channel_for UBERON:0013756 ! venous blood relationship: channels_from UBERON:0001982 ! capillary property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/c/c2/Venous_system_en.svg" xsd:anyURI [Term] id: UBERON:0001639 name: hepatic portal vein namespace: uberon def: "A portal vein that transports nutrients from the digestive tract to the liver[Kardong]." [http://sourceforge.net/tracker/?func=detail&aid=3091300&group_id=76834&atid=1205376, ISBN:0073040584, Wikipedia:Hepatic_portal_vein] synonym: "hepatic portal tree" EXACT [] synonym: "liver portal vein" EXACT [OBOL:automatic] synonym: "portal vein of liver" EXACT [OBOL:automatic] xref: AAO:0010214 xref: FMA:50735 xref: MA:0002132 xref: TAO:0005090 xref: VHOG:0000642 xref: Wikipedia:Hepatic_portal_vein xref: ZFA:0005090 is_a: UBERON:0002017 {source="MA"} ! portal vein relationship: BFO:0000050 UBERON:0010194 ! part of hepatic portal system relationship: channels_into UBERON:0002107 ! liver relationship: RO:0002131 UBERON:0002107 ! overlaps liver relationship: RO:0002202 UBERON:0005487 {gci_filler="NCBITaxon:40674", gci_relation="BFO:0000050", source="Wikipedia:Vitelline_vein"} ! develops from vitelline vein property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/3/33/Gray591.png" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI [Term] id: UBERON:0001640 name: celiac artery namespace: uberon def: "The first major branch of the abdominal aorta." [Wikipedia:Celiac_artery] synonym: "celiac tree" EXACT [] synonym: "coeliac artery" EXACT [Wikipedia:Celiac_artery] xref: EHDAA2:0004519 xref: EMAPA:35202 xref: FMA:50737 xref: GAID:483 xref: MA:0001931 xref: MESH:D002445 xref: NCIT:C52846 xref: SCTID:181340007 xref: UMLS:C0007569 {source="ncithesaurus:Coeliac_Artery"} xref: Wikipedia:Celiac_artery is_a: UBERON:0012254 ! abdominal aorta artery relationship: indirectly_supplies UBERON:0000160 {source="ISBN:0073040584"} ! intestine relationship: indirectly_supplies UBERON:0000945 {source="ISBN:0073040584"} ! stomach relationship: indirectly_supplies UBERON:0002106 {source="ISBN:0073040584"} ! spleen relationship: indirectly_supplies UBERON:0002107 {source="ISBN:0073040584"} ! liver relationship: RO:0002202 UBERON:0006002 {gci_filler="NCBITaxon:40674", gci_relation="BFO:0000050", source="Wikipedia"} ! develops from vitelline artery property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/6/65/Gray532.png" xsd:anyURI [Term] id: UBERON:0001645 name: trigeminal nerve namespace: uberon def: "Cranial nerve that has three branches - the ophthalmic (supplying the skin of the nose and upper jaw), the maxillary and the mandibular (supplying the lower jaw)." [ISBN:0471209627, Wikipedia:Trigeminal_nerve] synonym: "fifth cranial nerve" EXACT [] synonym: "trigeminal nerve [V]" EXACT [] synonym: "trigeminal nerve tree" EXACT [] synonym: "trigeminal V" EXACT [EHDAA2:0002084] synonym: "trigeminal v nerve" EXACT [] xref: AAO:0010470 xref: BAMS:5n xref: BAMS:nV xref: BAMS:Vn xref: BIRNLEX:869 xref: BM:VN xref: BTO:0001072 xref: EFO:0001402 xref: EHDAA2:0002084 xref: EHDAA:3738 xref: EMAPA:17576 xref: FMA:50866 xref: GAID:726 xref: HBA:9322 xref: MA:0001100 xref: MBA:901 xref: MESH:D014276 xref: MFMO:0000093 xref: NCIT:C12806 xref: neuronames:549 {source="BIRNLEX:869"} xref: SCTID:362459002 xref: TAO:0000697 xref: UMLS:C0040996 {source="ncithesaurus:Trigeminal_Nerve", source="BIRNLEX:869"} xref: VHOG:0000704 xref: Wikipedia:Trigeminal_nerve xref: XAO:0003092 xref: ZFA:0000697 is_a: UBERON:0001785 ! cranial nerve intersection_of: UBERON:0001785 ! cranial nerve intersection_of: extends_fibers_into UBERON:0002925 ! trigeminal nucleus intersection_of: RO:0002134 UBERON:0000165 ! innervates mouth intersection_of: RO:0002134 UBERON:0011648 ! innervates jaw muscle intersection_of: RO:0002134 UBERON:1000021 ! innervates skin of face relationship: extends_fibers_into UBERON:0002925 ! trigeminal nucleus relationship: RO:0002134 UBERON:0000165 ! innervates mouth relationship: RO:0002134 UBERON:0011648 ! innervates jaw muscle relationship: RO:0002134 UBERON:1000021 ! innervates skin of face relationship: RO:0002216 GO:0050964 {gci_filler="NCBITaxon:9255", gci_relation="BFO:0000050", source="PMID:22179203"} ! capable of part of detection of electrical stimulus involved in electroception relationship: RO:0002254 UBERON:0005239 {source="Wikipedia"} ! has developmental contribution from basal plate metencephalon property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/9/99/Gray778_Trigeminal.png" xsd:anyURI [Term] id: UBERON:0001651 name: right pulmonary artery namespace: uberon def: "The pulmonary artery that supplies the right lung." [UBERON:cjm] synonym: "right main pulmonary artery" EXACT [] synonym: "right pulmonary arterial tree" EXACT [] xref: EMAPA:37378 {source="MA:th"} xref: FMA:50872 xref: galen:RightPulmonaryArtery xref: MA:0002500 xref: NCIT:C33489 xref: SCTID:244235003 xref: UMLS:C0923924 {source="ncithesaurus:Right_Pulmonary_Artery"} xref: Wikipedia:Right_pulmonary_artery is_a: UBERON:0001637 ! artery intersection_of: UBERON:0001637 ! artery intersection_of: RO:0002178 UBERON:0002167 ! supplies right lung relationship: BFO:0000050 RO:0002577 ! part of system relationship: RO:0002170 UBERON:0002333 ! connected to pulmonary trunk relationship: RO:0002178 UBERON:0002167 ! supplies right lung property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/f/f6/Gray504.png" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/d/db/Alveoli_diagram.png" xsd:anyURI [Term] id: UBERON:0001652 name: left pulmonary artery namespace: uberon def: "The pulmonary artery that supplies the left lung." [UBERON:cjm] synonym: "left main pulmonary artery" EXACT [] synonym: "left pulmonary arterial tree" EXACT [] xref: EMAPA:37097 {source="MA:th"} xref: FMA:50873 xref: galen:LeftPulmonaryArtery xref: MA:0002032 xref: NCIT:C32971 xref: SCTID:244234004 xref: UMLS:C0923925 {source="ncithesaurus:Left_Pulmonary_Artery"} xref: Wikipedia:Left_pulmonary_artery is_a: UBERON:0001637 ! artery intersection_of: UBERON:0001637 ! artery intersection_of: RO:0002178 UBERON:0002168 ! supplies left lung relationship: BFO:0000050 RO:0002577 ! part of system relationship: RO:0002170 UBERON:0002333 ! connected to pulmonary trunk relationship: RO:0002178 UBERON:0002168 ! supplies left lung property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/f/f6/Gray504.png" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/d/db/Alveoli_diagram.png" xsd:anyURI [Term] id: UBERON:0001653 name: facial vein namespace: uberon def: "The anterior facial vein (facial vein) commences at the side of the root of the nose, and is a direct continuation of the angular vein where it also receives a small nasal branch. It lies behind the facial artery and follows a less tortuous course. It receives blood from the external palatine vein before it either joins the anterior branch of the retromandibular vein to form the common facial vein, or drains directly into the internal jugular vein. [WP,unvetted]." [Wikipedia:Facial_vein] synonym: "face vein" EXACT [OBOL:automatic] synonym: "vein of face" EXACT [OBOL:automatic] xref: AAO:0010513 xref: EMAPA:19220 xref: FMA:50874 xref: MA:0002115 xref: NCIT:C32579 xref: SCTID:181374006 xref: UMLS:C0226532 {source="ncithesaurus:Facial_Vein"} xref: Wikipedia:Facial_vein is_a: UBERON:0003496 ! head blood vessel is_a: UBERON:0009141 ! craniocervical region vein relationship: BFO:0000050 RO:0002577 ! part of system relationship: BFO:0000050 UBERON:0001456 ! part of face relationship: RO:0002376 UBERON:0001586 {source="FMA"} ! tributary of internal jugular vein property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/8/8c/Gray557.png" xsd:anyURI [Term] id: UBERON:0001675 name: trigeminal ganglion namespace: uberon def: "The cranial ganglion that is associated with and extends fibers into the trigeminal nerve." [http://orcid.org/0000-0002-6601-2165, http://www.ncbi.nlm.nih.gov/books/NBK53171, https://github.com/obophenotype/uberon/issues/693] synonym: "5th ganglion" EXACT [ZFA:0000295] synonym: "fifth ganglion" EXACT [ZFA:0000295] synonym: "ganglion of trigeminal complex" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "Gasserian ganglion" EXACT [Wikipedia:Trigeminal_ganglion] synonym: "semilunar ganglion" EXACT [ISBN:0471888893] synonym: "trigeminal V ganglion" EXACT [MA:0001080] xref: AAO:0011107 xref: BAMS:5Gn xref: BAMS:GV xref: BTO:0001231 xref: EFO:0000903 xref: EHDAA2:0002085 xref: EHDAA:2113 xref: EMAPA:16797 xref: FMA:52618 xref: GAID:725 xref: MA:0001080 xref: MAT:0000511 xref: MESH:D012668 xref: NCIT:C62642 xref: neuronames:1402 xref: SCTID:244449009 xref: TAO:0000295 xref: UMLS:C0040995 {source="ncithesaurus:Trigeminal_Ganglion"} xref: VHOG:0000694 xref: Wikipedia:Trigeminal_ganglion xref: XAO:0000427 xref: XAO:0000428 xref: ZFA:0000295 is_a: UBERON:0001714 ! cranial ganglion is_a: UBERON:0001800 {source="ncithesaurus"} ! sensory ganglion is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: UBERON:0001714 ! cranial ganglion intersection_of: extends_fibers_into UBERON:0001645 ! trigeminal nerve relationship: extends_fibers_into UBERON:0001645 ! trigeminal nerve relationship: RO:0002495 UBERON:0006304 {source="Bgee:AN"} ! immediate transformation of future trigeminal ganglion property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/6/69/Gray776.png" xsd:anyURI property_value: x_1.1:contributor https://github.com/ANiknejad property_value: x_1.1:contributor https://github.com/cmungall property_value: x_1.1:contributor https://github.com/mellybelly [Term] id: UBERON:0001676 name: occipital bone namespace: uberon def: "The bone at the lower, posterior part of the skull." [ISBN:0-683-40008-8, MP:0005269] xref: EMAPA:25112 xref: FMA:52735 xref: GAID:227 xref: MA:0001468 xref: MESH:D009777 xref: NCIT:C12757 xref: SCTID:181796003 xref: UMLS:C0028784 {source="ncithesaurus:Occipital_Bone"} xref: Wikipedia:Occipital_bone is_a: UBERON:0010428 {source="FMA"} ! flat bone is_a: UBERON:0011164 ! neurocranium bone relationship: BFO:0000050 UBERON:0005902 {source="FMA"} ! part of occipital region relationship: RO:0002131 UBERON:0002241 ! overlaps chondrocranium relationship: RO:0002131 UBERON:0003113 ! overlaps dermatocranium relationship: RO:0002160 NCBITaxon:117570 {source="WP"} ! only in taxon Teleostomi relationship: RO:0002170 UBERON:0001092 {gci_filler="NCBITaxon:9606", gci_relation="BFO:0000050", source="FMA"} ! connected to vertebral bone 1 relationship: RO:0002170 UBERON:0001677 {gci_filler="NCBITaxon:9606", gci_relation="BFO:0000050", source="FMA"} ! connected to sphenoid bone relationship: RO:0002202 UBERON:0003089 {source="PMID:11523816"} ! develops from sclerotome relationship: RO:0002221 UBERON:0003687 ! surrounds foramen magnum property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/2/27/Gray194.png" xsd:anyURI [Term] id: UBERON:0001677 name: sphenoid bone namespace: uberon def: "An unpaired bone situated at the base of the skull in front of the temporal bone and basilar part of the occipital bone. The sphenoid bone is one of the seven bones that articulate to form the orbit. Its shape somewhat resembles that of a butterfly or bat with its wings extended." [Wikipedia:Sphenoid_bone] synonym: "sphenoid" EXACT [] synonym: "sphenoidal bone" EXACT [] xref: CALOHA:TS-2343 xref: EMAPA:18340 xref: FMA:52736 xref: GAID:230 xref: MA:0001472 xref: MESH:D013100 xref: NCIT:C12790 xref: SCTID:272676008 xref: UMLS:C0037884 {source="ncithesaurus:Sphenoid_Bone"} xref: Wikipedia:Sphenoid_bone is_a: UBERON:0002513 ! endochondral bone is_a: UBERON:0003462 ! facial bone is_a: UBERON:0008193 {source="FMA"} ! pneumatized bone is_a: UBERON:0015060 ! sphenoid endochondral element intersection_of: UBERON:0015060 ! sphenoid endochondral element intersection_of: RO:0002473 UBERON:0002481 ! composed primarily of bone tissue relationship: RO:0002131 UBERON:0002241 ! overlaps chondrocranium relationship: RO:0002131 UBERON:0003113 ! overlaps dermatocranium relationship: RO:0002131 UBERON:0008895 ! overlaps splanchnocranium relationship: RO:0002170 UBERON:0000209 {gci_filler="NCBITaxon:9606", gci_relation="BFO:0000050", source="FMA"} ! connected to tetrapod frontal bone relationship: RO:0002170 UBERON:0001676 {gci_filler="NCBITaxon:9606", gci_relation="BFO:0000050", source="FMA"} ! connected to occipital bone relationship: RO:0002170 UBERON:0001679 {gci_filler="NCBITaxon:9606", gci_relation="BFO:0000050", source="FMA"} ! connected to ethmoid bone relationship: RO:0002170 UBERON:0002396 {gci_filler="NCBITaxon:9606", gci_relation="BFO:0000050", source="FMA"} ! connected to vomer relationship: RO:0002202 UBERON:0009193 {source="cjm"} ! develops from sphenoid cartilage element property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/6/66/Illu_cranial_bones2.jpg" xsd:anyURI [Term] id: UBERON:0001679 name: ethmoid bone namespace: uberon def: "A bone in the skull that separates the nasal cavity from the brain. As such, it is located at the roof of the nose, between the two orbits. The cubical bone is lightweight due to a spongy construction. The ethmoid bone is one of the bones that makes up the orbit of the eye[WP]." [Wikipedia:Ethmoid_bone] synonym: "ethmoid" EXACT [FMA:52740] synonym: "ethmoidal bone" EXACT [MP:0000101] xref: BTO:0004140 xref: EMAPA:19018 xref: FMA:52740 xref: GAID:212 xref: MA:0001483 xref: MESH:D005004 xref: NCIT:C12711 xref: SCTID:272674006 xref: UMLS:C0015027 {source="ncithesaurus:Ethmoid_Bone"} xref: VHOG:0001317 xref: Wikipedia:Ethmoid_bone is_a: UBERON:0002513 {source="ISBN:0073040584"} ! endochondral bone is_a: UBERON:0003462 ! facial bone is_a: UBERON:0011164 ! neurocranium bone relationship: BFO:0000050 UBERON:0002517 ! part of basicranium relationship: BFO:0000050 UBERON:0011241 ! part of ethmoid region relationship: RO:0002170 UBERON:0000209 {gci_filler="NCBITaxon:9606", gci_relation="BFO:0000050", source="FMA"} ! connected to tetrapod frontal bone relationship: RO:0002170 UBERON:0001677 {gci_filler="NCBITaxon:9606", gci_relation="BFO:0000050", source="FMA"} ! connected to sphenoid bone relationship: RO:0002170 UBERON:0002396 {gci_filler="NCBITaxon:9606", gci_relation="BFO:0000050", source="FMA"} ! connected to vomer relationship: RO:0002202 UBERON:0006227 ! develops from ethmoid bone primordium relationship: RO:0002433 UBERON:0011156 ! contributes to morphology of facial skeleton property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/6/66/Illu_cranial_bones2.jpg" xsd:anyURI [Term] id: UBERON:0001697 name: orbit of skull namespace: uberon def: "Subdivision of skeleton that is an anterolateral part of the cranium and structurally supports the eye. Includes bones formed and located in sclerotic layer of eyeball." [http://orcid.org/0000-0002-6601-2165, TAO:0001410, Wikipedia:Orbit_(anatomy)] synonym: "bony orbit" EXACT [] synonym: "eye socket" EXACT [] synonym: "orbit of skull" EXACT [FMA:53074] xref: BTO:0004687 xref: FMA:53074 xref: GAID:223 xref: galen:Orbit xref: MA:0002482 xref: MESH:D009915 xref: NCIT:C12347 xref: TAO:0001410 xref: UMLS:C0029180 {source="ncithesaurus:Orbit"} xref: Wikipedia:Orbit_(anatomy) xref: XAO:0003171 xref: ZFA:0001410 is_a: UBERON:0010313 ! neural crest-derived structure is_a: UBERON:0010912 ! subdivision of skeleton is_a: UBERON:0015212 ! lateral structure relationship: BFO:0000050 UBERON:0004088 ! part of orbital region relationship: BSPO:0000126 UBERON:0011156 {source="FMA-abduced-lr"} ! in lateral side of facial skeleton relationship: RO:0001015 UBERON:0000019 ! location of camera-type eye [Term] id: UBERON:0001703 name: neurocranium namespace: uberon def: "Subdivision of skeletal system that surrounds and protects the brain. Includes the skull base, sensory capsules and the central part of the skull roof." [PMID:11523816, TAO:MAH, Wikipedia:Neuroranium, ZFA:0001580] synonym: "brain box" EXACT [] xref: AAO:0010153 xref: EHDAA2:0000243 xref: EMAPA:17681 xref: FMA:53672 xref: MA:0000317 xref: SCTID:361731002 xref: TAO:0001580 xref: Wikipedia:Neuroranium xref: XAO:0003170 xref: ZFA:0001580 is_a: UBERON:0011158 {source="FMA"} ! primary subdivision of skull relationship: BFO:0000050 UBERON:0003128 ! part of cranium relationship: protects UBERON:0000955 ! brain relationship: RO:0001015 UBERON:0000955 ! location of brain relationship: RO:0002202 UBERON:0004761 ! develops from cartilaginous neurocranium [Term] id: UBERON:0001708 name: jaw skeleton namespace: uberon def: "Subdivision of skeleton which includes upper and lower jaw skeletons." [https://orcid.org/0000-0002-6601-2165, Wikipedia:Jaw] synonym: "jaw" EXACT [MA:0001905] synonym: "jaw cartilage" EXACT [ZFA:0001227] synonym: "mandibular arch skeleton" EXACT [ZFA:0001227] xref: AAO:0000988 xref: BTO:0001749 xref: EMAPA:35455 xref: FMA:54396 xref: GAID:214 xref: galen:Jaw xref: MA:0001905 xref: MESH:D007568 xref: NCIT:C48821 xref: SCTID:181811001 xref: TAO:0001227 xref: UMLS:C0022359 {source="ncithesaurus:Jaw"} xref: Wikipedia:Jaw xref: ZFA:0001227 is_a: UBERON:0010313 ! neural crest-derived structure is_a: UBERON:0010912 ! subdivision of skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: RO:0002576 UBERON:0011595 ! skeleton of jaw region relationship: BFO:0000050 UBERON:0011156 {source="cjm"} ! part of facial skeleton relationship: RO:0002131 UBERON:0008895 ! overlaps splanchnocranium relationship: RO:0002160 NCBITaxon:7776 ! only in taxon Gnathostomata relationship: RO:0002215 NBO:0000073 ! capable of chewing relationship: RO:0002576 UBERON:0011595 ! skeleton of jaw region [Term] id: UBERON:0001709 name: upper jaw region namespace: uberon def: "Subdivision of head that consists of the upper jaw skeletal elements plus associated soft tissue (skin, lips, muscle)[cjm]." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Upper_jaw] synonym: "maxillary part of mouth" EXACT [FMA:59399] xref: AAO:0000620 xref: EHDAA2:0002118 xref: EHDAA2:0004607 xref: EHDAA:8025 xref: EMAPA:17924 xref: FMA:59399 xref: ncithesaurus:Upper_Jaw xref: SCTID:362636001 xref: VHOG:0000454 xref: Wikipedia:Upper_jaw is_a: UBERON:0000475 ! organism subdivision is_a: UBERON:0010314 ! structure with developmental contribution from neural crest intersection_of: UBERON:0000475 ! organism subdivision intersection_of: RO:0002551 UBERON:0003277 ! has skeleton skeleton of upper jaw disjoint_from: UBERON:0001710 ! lower jaw region relationship: BFO:0000050 UBERON:0004089 ! part of midface relationship: BFO:0000050 UBERON:0011595 ! part of jaw region relationship: RO:0002551 UBERON:0003277 ! has skeleton skeleton of upper jaw property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/a/a7/Gray189.png" xsd:anyURI [Term] id: UBERON:0001710 name: lower jaw region namespace: uberon def: "Subdivision of head that consists of the lower jaw skeletal elements plus associated soft tissue (skin, lips, muscle)[cjm]." [Wikipedia:Lower_jaw] synonym: "mandibular part of mouth" EXACT [FMA:59398] xref: AAO:0000272 xref: EFO:0003660 xref: EHDAA2:0001018 xref: EHDAA:7995 xref: EMAPA:17906 xref: FMA:59398 xref: MESH:D008334 xref: ncithesaurus:Lower_Jaw xref: SCTID:362637005 xref: VHOG:0000453 xref: Wikipedia:Lower_jaw is_a: UBERON:0000475 ! organism subdivision is_a: UBERON:0010314 ! structure with developmental contribution from neural crest intersection_of: UBERON:0000475 ! organism subdivision intersection_of: RO:0002551 UBERON:0003278 ! has skeleton skeleton of lower jaw relationship: BFO:0000050 UBERON:0011595 ! part of jaw region relationship: RO:0002202 UBERON:0005867 {source="Wikipedia:Mandibular_prominence"} ! develops from mandibular prominence relationship: RO:0002551 UBERON:0003278 ! has skeleton skeleton of lower jaw property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/6/64/Gray176.png" xsd:anyURI [Term] id: UBERON:0001714 name: cranial ganglion namespace: uberon def: "The groups of nerve cell bodies associated with the twelve cranial nerves." [ISBN:0-683-40008-8, MGI:csmith, MP:0001081, PMID:9362461] synonym: "cranial ganglion" EXACT [] synonym: "cranial ganglion part of peripheral nervous system" EXACT [BIRNLEX:2597] synonym: "cranial ganglion/nerve" EXACT [] synonym: "cranial nerve ganglion" EXACT [] synonym: "cranial neural ganglion" EXACT [] synonym: "cranial neural tree organ ganglion" EXACT [OBOL:automatic] synonym: "ganglion of cranial nerve" EXACT [FMA:54502] synonym: "ganglion of cranial neural tree organ" EXACT [OBOL:automatic] xref: BIRNLEX:2597 xref: BTO:0000106 xref: EFO:0000902 xref: EMAPA:16659 xref: FMA:54502 xref: MA:0000213 xref: MA:0000214 xref: MAT:0000200 xref: MIAA:0000200 xref: SCTID:244448001 xref: TAO:0000013 xref: VHOG:0000076 xref: Wikipedia:Cranial_nerve_ganglion xref: XAO:0000027 xref: ZFA:0000013 is_a: UBERON:0000045 ! ganglion intersection_of: UBERON:0000045 ! ganglion intersection_of: extends_fibers_into UBERON:0034713 ! cranial neuron projection bundle relationship: BFO:0000050 RO:0002577 ! part of system relationship: BFO:0000050 UBERON:0000033 ! part of head relationship: extends_fibers_into UBERON:0034713 ! cranial neuron projection bundle [Term] id: UBERON:0001731 name: cavity of pharynx namespace: uberon def: "An anatomical space that is enclosed by a pharynx." [OBOL:automatic] synonym: "lumen of pharynx" EXACT [] synonym: "pharyngeal cavity" EXACT [] xref: AAO:0010435 xref: BSA:0000113 xref: BTO:0002097 xref: EMAPA:18381 xref: FMA:54935 xref: SCTID:180543003 xref: XAO:0000105 is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: RO:0002572 UBERON:0006562 ! luminal space of pharynx relationship: RO:0002202 UBERON:0001041 {source="XAO"} ! develops from foregut relationship: RO:0002572 UBERON:0006562 ! luminal space of pharynx [Term] id: UBERON:0001766 name: anterior chamber of eyeball namespace: uberon def: "The space in the eye, filled with aqueous humor, and bounded anteriorly by the cornea and a small portion of the sclera and posteriorly by a small portion of the ciliary body, the iris, and part of the crystalline lens." [MESH:A09.371.060.067, MP:0005205] synonym: "anterior chamber" EXACT [HP:0000593, MP:0010709] synonym: "anterior chamber of eye" EXACT [] synonym: "camera anterior" EXACT [] synonym: "eye anterior chamber" EXACT [] xref: BTO:0002084 xref: EHDAA2:0000129 xref: EHDAA:9033 xref: EMAPA:18231 xref: FMA:58078 xref: GAID:889 xref: MA:0000262 xref: MESH:D000867 xref: NCIT:C12667 xref: SCTID:181160009 xref: UMLS:C0003151 {source="ncithesaurus:Anterior_Chamber_of_the_Eye"} xref: VHOG:0001431 xref: Wikipedia:Anterior_chamber_of_eyeball is_a: UBERON:0006311 {source="FMA"} ! chamber of eyeball relationship: BFO:0000050 UBERON:0001801 ! part of anterior segment of eyeball relationship: RO:0002433 UBERON:0001801 ! contributes to morphology of anterior segment of eyeball property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg" xsd:anyURI [Term] id: UBERON:0001768 name: uvea namespace: uberon def: "The pigmented middle of the three concentric layers that make up an eye, consisting of the iris, ciliary body and choroid[WP,edited]." [MP:0005197, Wikipedia:Uvea] synonym: "tunica vasculosa of eyeball" EXACT [FMA:58103] synonym: "uvea" EXACT [FMA:58103] synonym: "uveal tract" EXACT [FMA:58103] xref: CALOHA:TS-2228 xref: EMAPA:35901 xref: FMA:58103 xref: GAID:912 xref: MA:0002480 xref: MESH:D014602 xref: NCIT:C12811 xref: SCTID:280648000 xref: UMLS:C0042160 {source="ncithesaurus:Uvea"} xref: Wikipedia:Uvea is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0004923 {source="FMA"} ! organ component layer is_a: UBERON:0010314 ! structure with developmental contribution from neural crest relationship: BFO:0000050 UBERON:0001801 ! part of anterior segment of eyeball relationship: BFO:0000051 UBERON:0001769 ! has part iris relationship: BFO:0000051 UBERON:0001775 ! has part ciliary body relationship: BFO:0000051 UBERON:0001776 ! has part optic choroid relationship: RO:0002433 UBERON:0000019 ! contributes to morphology of camera-type eye property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/e/eb/Gray869.png" xsd:anyURI [Term] id: UBERON:0001769 name: iris namespace: uberon def: "The adjustable membrane, composed of the stroma and pigmented epithelium, located just in front of the crystalline lens within the eye." [ISBN:0-683-40008-8, MP:0001322] xref: AAO:0010347 xref: BTO:0000653 xref: CALOHA:TS-0491 xref: EFO:0004245 xref: EMAPA:19154 xref: EV:0100345 xref: FMA:58235 xref: GAID:917 xref: MA:0000273 xref: MESH:D007498 xref: NCIT:C12737 xref: SCTID:181164000 xref: TAO:0001238 xref: UMLS:C0022077 {source="ncithesaurus:Iris"} xref: VHOG:0000101 xref: Wikipedia:Iris_(anatomy) xref: XAO:0000185 xref: ZFA:0001238 is_a: UBERON:0000481 ! multi-tissue structure is_a: UBERON:0004121 ! ectoderm-derived structure relationship: BFO:0000050 UBERON:0011892 ! part of anterior uvea relationship: RO:0002202 UBERON:0004128 {source="XAO"} ! develops from optic vesicle relationship: RO:0002433 UBERON:0011892 ! contributes to morphology of anterior uvea [Term] id: UBERON:0001772 name: corneal epithelium namespace: uberon def: "The smooth stratified squamous epithelium that covers the outer surface of the cornea." [MESH:A09.371.060.217.325, MGI:smb, MP:0006000] synonym: "anterior corneal epithelium" EXACT [] synonym: "cornea epithelial tissue" EXACT [OBOL:automatic] synonym: "cornea epithelium" EXACT [OBOL:automatic] synonym: "epithelial tissue of cornea" EXACT [OBOL:automatic] synonym: "epithelium anterius (cornea)" EXACT [] synonym: "epithelium corneæ anterior layer" EXACT [] synonym: "epithelium of cornea" EXACT [] synonym: "external epithelium of cornea" EXACT [] xref: BTO:0000287 xref: CALOHA:TS-0173 xref: EFO:0001917 xref: EHDAA2:0000319 xref: EMAPA:17162 xref: FMA:58263 xref: GAID:895 xref: MA:0001243 xref: MESH:D019573 xref: NCIT:C12928 xref: SCTID:368825001 xref: TAO:0002187 xref: UMLS:C0459875 {source="ncithesaurus:Corneal_Epithelium"} xref: Wikipedia:Corneal_epithelium xref: ZFA:0001683 is_a: UBERON:0000488 {gci_filler="NCBITaxon:9606", gci_relation="BFO:0000050", source="FMA"} ! atypical epithelium is_a: UBERON:0010304 {gci_relation="BFO:0000050", gci_filler="NCBITaxon:7955"} ! non-keratinized stratified squamous epithelium is_a: UBERON:0010313 ! neural crest-derived structure is_a: UBERON:0015808 ! eye epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: RO:0002007 UBERON:0000964 ! bounding layer of cornea relationship: RO:0002007 UBERON:0000964 ! bounding layer of cornea relationship: RO:0002202 UBERON:0000076 {source="ISBN:0781772214"} ! develops from external ectoderm relationship: RO:0002433 UBERON:0000964 ! contributes to morphology of cornea property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/6/66/Gray871.png" xsd:anyURI [Term] id: UBERON:0001773 name: sclera namespace: uberon def: "Opaque fibrous outer layer of the eyeball[ZFA,Kardong,WP]." [Wikipedia:Sclera, ZFIN:ZDB-PUB-050701-15] xref: AAO:0010354 xref: BTO:0001606 xref: EMAPA:19027 xref: EV:0100342 xref: FMA:58269 xref: GAID:911 xref: MA:0000280 xref: MESH:D012590 xref: NCIT:C12784 xref: SCTID:181163006 xref: UMLS:C0036410 {source="ncithesaurus:Sclera"} xref: VHOG:0001274 xref: Wikipedia:Sclera xref: XAO:0000183 xref: ZFA:0005563 is_a: UBERON:0000064 ! organ part is_a: UBERON:0010313 ! neural crest-derived structure relationship: BFO:0000050 UBERON:0012430 {source="FMA"} ! part of tunica fibrosa of eyeball relationship: BFO:0000051 CL:0000347 {source="ZFA"} ! has part scleral cell relationship: RO:0000086 PATO:0000963 ! has quality opaque relationship: RO:0002202 UBERON:0003314 {source="ISBN:0781772214"} ! develops from eye mesenchyme relationship: RO:0002433 UBERON:0000019 ! contributes to morphology of camera-type eye property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg" xsd:anyURI [Term] id: UBERON:0001774 name: skeletal muscle of trunk namespace: uberon def: "A skeletal muscle organ that is part of the trunk region." [http://orcid.org/0000-0002-6601-2165] synonym: "body musculature" EXACT [ZFA:0000473] synonym: "muscle of trunk" EXACT [FMA:58274] synonym: "muscle organ of torso" EXACT [OBOL:automatic] synonym: "muscle organ of trunk" EXACT [OBOL:automatic] synonym: "torso muscle organ" EXACT [OBOL:automatic] synonym: "trunk muscle" EXACT [] synonym: "trunk muscle organ" EXACT [OBOL:automatic] synonym: "trunk musculature" EXACT [] xref: AAO:0000611 xref: EMAPA:35888 xref: FMA:58274 xref: MA:0000514 xref: TAO:0000473 xref: XAO:0003230 xref: ZFA:0000473 is_a: UBERON:0005177 ! trunk region element is_a: UBERON:0014892 ! skeletal muscle organ, vertebrate intersection_of: UBERON:0014892 ! skeletal muscle organ, vertebrate intersection_of: BFO:0000050 UBERON:0002100 ! part of trunk relationship: BFO:0000050 UBERON:0004479 {source="prolog"} ! part of musculature of trunk [Term] id: UBERON:0001775 name: ciliary body namespace: uberon def: "The thickened portion of the vascular tunic, which lies between the choroid and the iris, composed of ciliary muscle and ciliary processes." [ISBN:0-683-40008-8, MP:0005099, Wikipedia:Ciliary_body] synonym: "ocular ciliary body" EXACT [] xref: AAO:0010341 xref: BTO:0000260 xref: CALOHA:TS-0694 xref: EMAPA:19065 xref: EV:0100346 xref: FMA:58295 xref: GAID:916 xref: MA:0000264 xref: MESH:D002924 xref: NCIT:C12345 xref: neuronames:1571 xref: SCTID:263340007 xref: UMLS:C0008779 {source="ncithesaurus:Ciliary_Body"} xref: VHOG:0000102 xref: Wikipedia:Ciliary_body xref: XAO:0000186 is_a: UBERON:0000481 ! multi-tissue structure is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0010314 ! structure with developmental contribution from neural crest relationship: BFO:0000050 UBERON:0011892 ! part of anterior uvea relationship: BFO:0000051 UBERON:0001605 ! has part ciliary muscle relationship: BFO:0000051 UBERON:0010427 ! has part ciliary processes relationship: RO:0002202 UBERON:0002346 {source="ISBN:0781772214"} ! develops from neurectoderm relationship: RO:0002433 UBERON:0011892 ! contributes to morphology of anterior uvea property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg" xsd:anyURI [Term] id: UBERON:0001776 name: optic choroid namespace: uberon def: "Vascular layer containing connective tissue, of the eye lying between the retina and the sclera. The choroid provides oxygen and nourishment to the outer layers of the retina. Along with the ciliary body and iris, the choroid forms the uveal tract[WP]." [Wikipedia:Choroid] synonym: "choroid" EXACT [MA:0000263] synonym: "choroid coat" EXACT [Wikipedia:Choroid] synonym: "choroidea" EXACT [Wikipedia:Choroid] synonym: "eye choroid" EXACT [VHOG:0001568] synonym: "posterior uvea" EXACT [Wikipedia:Uvea#Regions] xref: BTO:0001829 xref: CALOHA:TS-2054 xref: EMAPA:19077 xref: EV:0100347 xref: FMA:58298 xref: GAID:913 xref: MA:0000263 xref: MESH:D002829 xref: NCIT:C12344 xref: SCTID:181172003 xref: TAO:0005229 xref: UMLS:C0008520 {source="ncithesaurus:Choroid"} xref: VHOG:0001568 xref: Wikipedia:Choroid xref: ZFA:0005229 is_a: UBERON:0002203 ! vasculature of eye disjoint_from: UBERON:0011892 {source="lexical"} ! anterior uvea relationship: BFO:0000050 UBERON:0001768 {source="MA"} ! part of uvea relationship: BFO:0000050 UBERON:0019207 ! part of chorioretinal region relationship: RO:0002131 UBERON:0001802 {source="Wikipedia"} ! overlaps posterior segment of eyeball relationship: RO:0002220 UBERON:0000966 ! adjacent to retina relationship: RO:0002220 UBERON:0001773 ! adjacent to sclera relationship: RO:0002220 UBERON:0011892 ! adjacent to anterior uvea relationship: RO:0002433 UBERON:0001768 ! contributes to morphology of uvea property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg" xsd:anyURI [Term] id: UBERON:0001777 name: substantia propria of cornea namespace: uberon def: "The lamellated connective tissue of the cornea between the Bowman and Descemet membranes." [ISBN:0-683-40008-8, MESH:A09.371.060.217.228, MP:0005300] synonym: "corneal stroma" EXACT [MA:0001245] synonym: "stroma of cornea" EXACT [] xref: CALOHA:TS-1138 xref: EFO:0002514 xref: EMAPA:17602 xref: FMA:58306 xref: GAID:893 xref: MA:0001245 xref: MESH:D003319 xref: NCIT:C12699 xref: SCTID:362511000 xref: TAO:0002189 xref: UMLS:C0010040 {source="ncithesaurus:Corneal_Stroma"} xref: Wikipedia:Corneal_stroma xref: ZFA:0001685 is_a: UBERON:0003891 ! stroma is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: UBERON:0003891 ! stroma intersection_of: BFO:0000050 UBERON:0000964 ! part of cornea relationship: BFO:0000050 UBERON:0000964 ! part of cornea relationship: RO:0002202 UBERON:0007213 ! develops from mesenchyme derived from head neural crest relationship: RO:0002220 UBERON:0004367 ! adjacent to Descemet's membrane relationship: RO:0002220 UBERON:0004370 ! adjacent to anterior limiting lamina of cornea relationship: RO:0002433 UBERON:0000964 ! contributes to morphology of cornea property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/6/66/Gray871.png" xsd:anyURI [Term] id: UBERON:0001778 name: ciliary epithelium namespace: uberon def: "A double layer covering the ciliary body that produces aqueous humor." [Wikipedia:Ciliary_body#Ciliary_epithelium] synonym: "ciliary body epithelium" EXACT [FMA:58464] synonym: "epithelium of ciliary body" EXACT [FMA:58464] synonym: "ocular ciliary epithelium" EXACT [] xref: BTO:0001770 xref: CALOHA:TS-0695 xref: EMAPA:35239 xref: FMA:58464 xref: MA:0001238 xref: NCIT:C32314 xref: SCTID:280870004 xref: UMLS:C0459736 {source="ncithesaurus:Ciliary_Epithelium"} xref: Wikipedia:Ciliary_body#Ciliary_epithelium is_a: UBERON:0000488 {source="FMA"} ! atypical epithelium is_a: UBERON:0015808 ! eye epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: BFO:0000050 UBERON:0001775 ! part of ciliary body relationship: BFO:0000050 UBERON:0001775 {source="MA"} ! part of ciliary body relationship: BFO:0000051 GO:0048770 {source="MP"} ! has part pigment granule relationship: RO:0003000 UBERON:0001796 {source="Wikipedia"} ! produces aqueous humor of eyeball [Term] id: UBERON:0001779 name: iris stroma namespace: uberon def: "The delicate vascular connective tissue that lies between the anterior surface of the iris and the pars iridica retinae." [http://www.drugs.com/dict/stroma-of-iris.html, Wikipedia:Iris_stroma] synonym: "iridial stroma" EXACT [] synonym: "stroma of iris" EXACT [] xref: EMAPA:35451 xref: FMA:58526 xref: MA:0002777 xref: SCTID:280882008 xref: Wikipedia:Iris_stroma xref: ZFA:0005569 is_a: UBERON:0003891 ! stroma is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0003891 ! stroma intersection_of: BFO:0000050 UBERON:0001769 ! part of iris relationship: BFO:0000050 UBERON:0001769 ! part of iris relationship: RO:0002433 UBERON:0001769 ! contributes to morphology of iris property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/5/55/Gray883.png" xsd:anyURI [Term] id: UBERON:0001780 name: spinal nerve namespace: uberon def: "The any of the paired peripheral nerves formed by the union of the dorsal and ventral spinal roots from each spinal cord segment[MP,modified]." [MESH:A08.800.800.720, MP:0001077] synonym: "backbone nerve" EXACT [OBOL:automatic] synonym: "nerve of backbone" EXACT [OBOL:automatic] synonym: "nerve of spinal column" EXACT [OBOL:automatic] synonym: "nerve of spine" EXACT [OBOL:automatic] synonym: "nerve of vertebral column" EXACT [OBOL:automatic] synonym: "spinal column nerve" EXACT [OBOL:automatic] synonym: "spinal nerve tree" EXACT [] synonym: "spine nerve" EXACT [OBOL:automatic] synonym: "vertebral column nerve" EXACT [OBOL:automatic] xref: AAO:0011101 xref: BAMS:spin xref: BTO:0000870 xref: EHDAA2:0001898 xref: EMAPA:16989 xref: FMA:5858 xref: GAID:841 xref: MA:0000233 xref: MESH:D013127 xref: NCIT:C12792 xref: neuronames:1228 xref: SCTID:361099009 xref: UMLS:C0037941 {source="ncithesaurus:Spinal_Nerve"} xref: VHOG:0000824 xref: Wikipedia:Spinal_nerve xref: XAO:0003101 is_a: UBERON:0001021 ! nerve intersection_of: UBERON:0001021 ! nerve intersection_of: extends_fibers_into UBERON:0002240 ! spinal cord relationship: BFO:0000050 RO:0002577 ! part of system relationship: extends_fibers_into UBERON:0002240 ! spinal cord property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/d/d2/Spinal_nerve.svg" xsd:anyURI [Term] id: UBERON:0001781 name: layer of retina namespace: uberon def: "Any of the layers that make up the retina[MP]." [MP:0003727] synonym: "retina layer" EXACT [] synonym: "retina neuronal layer" EXACT [MP:0006069] synonym: "retinal layer" EXACT [] synonym: "retinal neuronal layer" EXACT [MP:0006069] xref: AAO:0010353 xref: EMAPA:35742 xref: FMA:58617 xref: MA:0001319 xref: NCIT:C49328 xref: SCTID:280657006 xref: UMLS:C0459649 {source="ncithesaurus:Retina_Layer"} xref: XAO:0000266 is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0022303 ! nervous system cell part layer relationship: BFO:0000050 UBERON:0000966 ! part of retina relationship: RO:0002433 UBERON:0000966 ! contributes to morphology of retina [Term] id: UBERON:0001785 name: cranial nerve namespace: uberon def: "Cranial nerves are nerves that emerge directly from the brain, in contrast to spinal nerves, which emerge from segments of the spinal cord." [Wikipedia:Cranial_nerve] synonym: "cranial neural tree organ" EXACT [] xref: AAO:0000108 xref: BAMS:cran xref: BIRNLEX:1623 xref: BTO:0001104 xref: EHDAA2:0000323 xref: EMAPA:17264 xref: FMA:5865 xref: GAID:802 xref: HBA:9299 xref: MA:0000215 xref: MBA:967 xref: MESH:D003391 xref: NCIT:C12700 xref: neuronames:1227 xref: SCTID:244447006 xref: TAO:0000641 xref: UMLS:C0010268 {source="BIRNLEX:1623", source="ncithesaurus:Cranial_Nerve"} xref: UMLS:C1269897 {source="BIRNLEX:1623"} xref: VHOG:0000279 xref: Wikipedia:Cranial_nerve xref: XAO:0000429 xref: XAO:0003089 xref: ZFA:0000641 is_a: UBERON:0011779 ! nerve of head region is_a: UBERON:0034713 ! cranial neuron projection bundle intersection_of: UBERON:0001021 ! nerve intersection_of: BSPO:0000096 UBERON:0001780 ! anterior to spinal nerve intersection_of: extends_fibers_into UBERON:0000955 ! brain relationship: BSPO:0000096 UBERON:0001780 ! anterior to spinal nerve relationship: RO:0002254 UBERON:0003099 ! has developmental contribution from cranial neural crest property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/1/18/Brain_human_normal_inferior_view_with_labels_en-2.svg" xsd:anyURI property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/8/84/Brain_human_normal_inferior_view_with_labels_en.svg" xsd:anyURI [Term] id: UBERON:0001796 name: aqueous humor of eyeball namespace: uberon def: "A thick watery refractive medium that fills the space between the lens and the cornea[WP]." [Wikipedia:Aqueous_humor] synonym: "aqueous humor" EXACT [] synonym: "aqueous humour" EXACT [EHDAA2:0000139] xref: EHDAA2:0000139 xref: EHDAA:10196 xref: EMAPA:18232 xref: ENVO:02000024 xref: FMA:58819 xref: GAID:890 xref: MA:0001236 xref: MESH:D001082 xref: NCIT:C13190 xref: SCTID:280587006 xref: UMLS:C0003662 {source="ncithesaurus:Aqueous_Humor"} xref: VHOG:0000548 xref: Wikipedia:Aqueous_humor xref: ZFA:0005564 is_a: UBERON:0006312 ! ocular refractive media is_a: UBERON:0006314 ! bodily fluid relationship: BFO:0000050 UBERON:0001766 ! part of anterior chamber of eyeball relationship: RO:0002433 UBERON:0001766 ! contributes to morphology of anterior chamber of eyeball property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg" xsd:anyURI [Term] id: UBERON:0001800 name: sensory ganglion namespace: uberon def: "The clusters of neurons in the somatic peripheral nervous system which contain the cell bodies of sensory nerve axons, interneurons and non-neuronal supporting cells." [MP:0000960] xref: AEO:0001000 xref: BTO:0005630 xref: EMAPA:36596 xref: FMA:5885 xref: MA:0002566 xref: MESH:D017950 xref: NCIT:C13060 xref: UMLS:C0206429 {source="ncithesaurus:Sensory_Ganglion"} is_a: UBERON:0000045 ! ganglion intersection_of: UBERON:0000045 ! ganglion intersection_of: extends_fibers_into UBERON:0001027 ! sensory nerve relationship: BFO:0000050 RO:0002577 ! part of system relationship: extends_fibers_into UBERON:0001027 ! sensory nerve [Term] id: UBERON:0001801 name: anterior segment of eyeball namespace: uberon def: "Any of the parts of the eye that lie in front of, or ventral to, the lens (inclusive)." [ISBN:0-683-40008-8, MESH:A09.371.060, MP:0005193] synonym: "anterior eye segment" EXACT [] synonym: "anterior segment eye" EXACT [ZFA:0005566] synonym: "anterior segment of eye" EXACT [] synonym: "anterior segment of the eye" EXACT [] synonym: "eye anterior segment" EXACT [] synonym: "segmentum anterius (bulbus oculi)" EXACT [] xref: EMAPA:36594 xref: FMA:58865 xref: MA:0002484 xref: MESH:D000869 xref: NCIT:C12668 xref: SCTID:280658001 xref: UMLS:C0003153 {source="ncithesaurus:Anterior_Eye_Segment"} xref: Wikipedia:Anterior_segment_of_eyeball xref: ZFA:0005566 is_a: UBERON:0000063 ! organ subunit is_a: UBERON:0004121 ! ectoderm-derived structure disjoint_from: UBERON:0001802 {source="lexical"} ! posterior segment of eyeball relationship: BSPO:0000123 UBERON:0010230 {source="cjm"} ! in anterior side of eyeball of camera-type eye relationship: RO:0002433 UBERON:0000019 ! contributes to morphology of camera-type eye property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/b/ba/Cataract_in_human_eye.png" xsd:anyURI [Term] id: UBERON:0001802 name: posterior segment of eyeball namespace: uberon def: "Any of the parts of the eye that lie in back of, or dorsal to, the lens (but not inclusive)." [ISBN:0-683-40008-8, MP:0005195] synonym: "eye posterior segment" EXACT [] synonym: "posterior eye segment" EXACT [] synonym: "posterior segment eye" EXACT [ZFA:0005567] synonym: "posterior segment of eye" EXACT [] synonym: "posterior segment of the eye" EXACT [] synonym: "segmentum posterius (bulbus oculi)" EXACT [] xref: EMAPA:36595 xref: FMA:58868 xref: MA:0002485 xref: NCIT:C12906 xref: SCTID:280659009 xref: UMLS:C0278450 {source="ncithesaurus:Posterior_Eye_Segment"} xref: Wikipedia:Posterior_segment_of_eyeball xref: ZFA:0005567 is_a: UBERON:0000063 ! organ subunit is_a: UBERON:0004121 ! ectoderm-derived structure relationship: BSPO:0000122 UBERON:0010230 {source="cjm"} ! in posterior side of eyeball of camera-type eye relationship: RO:0002433 UBERON:0000019 ! contributes to morphology of camera-type eye property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg" xsd:anyURI [Term] id: UBERON:0001803 name: epithelium of lens namespace: uberon def: "A layer of epithelial cells that is part of the eye." [http://orcid.org/0000-0002-6601-2165] synonym: "epithelial tissue of eye lens" EXACT [OBOL:automatic] synonym: "epithelial tissue of lens" EXACT [OBOL:automatic] synonym: "epithelium of eye lens" EXACT [OBOL:automatic] synonym: "eye lens epithelial tissue" EXACT [OBOL:automatic] synonym: "eye lens epithelium" EXACT [OBOL:automatic] synonym: "lens epithelial tissue" EXACT [OBOL:automatic] synonym: "lens epithelium" EXACT [] xref: BTO:0001873 xref: CALOHA:TS-0543 xref: EMAPA:32871 xref: FMA:58871 xref: MA:0001301 xref: SCTID:362523006 xref: TAO:0001326 xref: Wikipedia:Lens_(anatomy)#Lens_Epithelium xref: XAO:0004094 xref: ZFA:0001326 is_a: UBERON:0000484 ! simple cuboidal epithelium is_a: UBERON:0015808 ! eye epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: BFO:0000050 UBERON:0000965 ! part of lens of camera-type eye relationship: BFO:0000050 UBERON:0000965 ! part of lens of camera-type eye relationship: RO:0002433 UBERON:0000965 ! contributes to morphology of lens of camera-type eye property_value: IAO:0000232 "this class is the superclass of the anterior epithelium and equatorial epithlium, although the term 'lens epithelium' may refer specifically to the former" xsd:string [Term] id: UBERON:0001804 name: capsule of lens namespace: uberon def: "The elastic, clear, membrane-like structure, that is outer most layer of the lens." [MGI:smb, MP:0003236, PMID:15483628] synonym: "lens capsule" EXACT [] xref: EHDAA2:0000977 xref: EMAPA:18237 xref: FMA:58881 xref: MA:0001300 xref: NCIT:C32975 xref: SCTID:244500004 xref: UMLS:C0229232 {source="ncithesaurus:Lens_Capsule"} xref: VHOG:0000550 xref: Wikipedia:Lens_(anatomy)#Lens_capsule xref: ZFA:0005574 is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0005764 ! acellular membrane intersection_of: UBERON:0000476 ! acellular anatomical structure intersection_of: RO:0002007 UBERON:0000965 ! bounding layer of lens of camera-type eye relationship: BFO:0000051 CHEBI:35722 ! has part sulfated glycosaminoglycan relationship: BFO:0000051 GO:0005587 ! has part collagen type IV trimer relationship: RO:0000086 PATO:0000964 ! has quality transparent relationship: RO:0002007 UBERON:0000965 ! bounding layer of lens of camera-type eye relationship: RO:0002202 UBERON:0005614 {source="EHDAA2"} ! develops from lens anterior epithelium property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/5/55/Gray883.png" xsd:anyURI [Term] id: UBERON:0001805 name: autonomic ganglion namespace: uberon def: "Ganglion that has dendrites that form a junction between autonomic nerves originating from the central nervous system and autonomic nerves innervating their target organs in the periphery. There are two subtypes, sympathetic ganglion and parasympathetic ganglion." [Wikipedia:Autonomic_ganglion] synonym: "autonomic nervous system ganglion" EXACT [OBOL:automatic] synonym: "ganglion of autonomic nervous system" EXACT [OBOL:automatic] synonym: "ganglion of visceral nervous system" EXACT [OBOL:automatic] synonym: "visceral nervous system ganglion" EXACT [OBOL:automatic] xref: AEO:0001001 xref: CALOHA:TS-2340 xref: EMAPA:17157 xref: EMAPA:18221 xref: FMA:5889 xref: MA:0000220 xref: MESH:D005725 xref: NCIT:C12720 xref: UMLS:C0017068 {source="ncithesaurus:Autonomic_Ganglion"} xref: Wikipedia:Autonomic_ganglion is_a: UBERON:0003338 ! ganglion of peripheral nervous system intersection_of: UBERON:0000045 ! ganglion intersection_of: BFO:0000050 UBERON:0002410 ! part of autonomic nervous system relationship: BFO:0000050 RO:0002577 ! part of system relationship: BFO:0000050 UBERON:0002410 ! part of autonomic nervous system relationship: extends_fibers_into UBERON:0034728 ! autonomic nerve property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/f/f7/Gray839.png" xsd:anyURI [Term] id: UBERON:0001806 name: sympathetic ganglion namespace: uberon def: "A ganglion of the sympathetic nervous system. Examples: paravertebral and the prevertebral ganglia, which include the sympathetic chain ganglia, the superior, middle, and inferior cervical ganglia, and the aorticorenal, celiac, and stellate ganglia." [http://orcid.org/0000-0002-6601-2165, MP:0001008] synonym: "ganglion of sympathetic nervous system" EXACT [OBOL:automatic] synonym: "ganglion of sympathetic part of autonomic division of nervous system" EXACT [OBOL:automatic] synonym: "ganglion sympatheticum" EXACT [] synonym: "sympathetic nervous system ganglion" EXACT [OBOL:automatic] synonym: "sympathetic part of autonomic division of nervous system ganglion" EXACT [OBOL:automatic] xref: AAO:0010773 xref: BTO:0001333 xref: CALOHA:TS-0994 xref: EHDAA2:0001969 xref: EMAPA:17157 xref: FMA:5890 xref: MA:0000226 xref: NCIT:C12467 xref: SCTID:362485003 xref: UMLS:C0017071 {source="ncithesaurus:Sympathetic_Ganglion"} xref: Wikipedia:Sympathetic_ganglion is_a: UBERON:0001805 ! autonomic ganglion is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: UBERON:0000045 ! ganglion intersection_of: BFO:0000050 UBERON:0000013 ! part of sympathetic nervous system relationship: BFO:0000050 UBERON:0000013 ! part of sympathetic nervous system relationship: extends_fibers_into UBERON:0034729 ! sympathetic nerve relationship: RO:0002202 UBERON:0003083 {source="DOI:10.1101/gr.157586.113", source="ISBN:0073040584"} ! develops from trunk neural crest relationship: RO:0002433 UBERON:0000013 ! contributes to morphology of sympathetic nervous system property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/f/f7/Gray839.png" xsd:anyURI [Term] id: UBERON:0001833 name: lip namespace: uberon def: "One of the two fleshy folds which surround the opening of the mouth." [http://www.medterms.com/script/main/art.asp?articlekey=9458, Wikipedia:Lip] xref: BTO:0001647 xref: CALOHA:TS-0558 xref: EMAPA:32839 xref: FMA:59816 xref: GAID:76 xref: galen:Lip xref: MA:0000343 xref: MESH:D008046 xref: NCIT:C12220 xref: SCTID:181221003 xref: TAO:0007006 xref: UMLS:C0023759 {source="ncithesaurus:Lip"} xref: VHOG:0000677 xref: Wikipedia:Lip xref: ZFA:0007006 is_a: UBERON:0003102 {source="ZFA"} ! surface structure relationship: BFO:0000050 UBERON:0000165 {source="BTO", source="FMA-implicit", source="VHOG", source="ZFA"} ! part of mouth relationship: RO:0002221 UBERON:0000166 {source="cjm"} ! surrounds oral opening relationship: RO:0002433 UBERON:0000165 ! contributes to morphology of mouth property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/9/90/Lips.JPG" xsd:anyURI property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/9/99/Mouth.jpg" xsd:anyURI [Term] id: UBERON:0001834 name: upper lip namespace: uberon def: "Lip that covers the upper portion of the mouth.[TAO]." [TAO:0001970, Wikipedia:Upper_lip] synonym: "upper jaw lip" EXACT [https://orcid.org/0000-0002-6601-2165] xref: EMAPA:17925 xref: FMA:59817 xref: MA:0000919 xref: SCTID:245776003 xref: TAO:0001970 xref: VHOG:0001750 xref: Wikipedia:Upper_lip xref: ZFA:0005226 is_a: UBERON:0001833 ! lip intersection_of: UBERON:0001833 ! lip intersection_of: BFO:0000050 UBERON:0001709 ! part of upper jaw region relationship: BFO:0000050 UBERON:0001709 ! part of upper jaw region relationship: RO:0002495 UBERON:0011592 ! immediate transformation of future upper lip property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/d/d4/Illu01_head_neck.jpg" xsd:anyURI [Term] id: UBERON:0001835 name: lower lip namespace: uberon def: "Lip that covers the lower portion of the mouth.[TAO]." [TAO:0002060, Wikipedia:Lower_lip] synonym: "lower jaw lip" EXACT [https://orcid.org/0000-0002-6601-2165] xref: EHDAA2:0001020 xref: EMAPA:17909 xref: FMA:59818 xref: MA:0000921 xref: NCIT:C94572 xref: SCTID:245777007 xref: TAO:0002060 xref: UMLS:C0458583 {source="ncithesaurus:Lower_Lip"} xref: Wikipedia:Lower_lip xref: ZFA:0005225 is_a: UBERON:0001833 ! lip intersection_of: UBERON:0001833 ! lip intersection_of: BFO:0000050 UBERON:0001710 ! part of lower jaw region relationship: BFO:0000050 UBERON:0001710 ! part of lower jaw region relationship: RO:0002202 UBERON:0011596 ! develops from future lower lip property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/9/99/Mouth.jpg" xsd:anyURI [Term] id: UBERON:0001851 name: cortex namespace: uberon def: "Outermost layer of an organ[WP]." [Wikipedia:Cortex_(anatomy)] synonym: "cortex" EXACT [FMA:61109] synonym: "cortex of organ" EXACT [] xref: EFO:0000383 xref: EHDAA:9344 xref: FMA:61109 xref: galen:Cortex xref: Wikipedia:Cortex_(anatomy) is_a: UBERON:0000064 ! organ part relationship: RO:0002007 UBERON:0000062 ! bounding layer of organ [Term] id: UBERON:0001884 name: phrenic nerve namespace: uberon def: "A nerve that arises from the caudal cervical nerves and is primarily the motor nerve of the diaphragm but also sends sensory fibers to the pericardium." [VHOG:0000728] xref: BAMS:phn xref: BTO:0001063 xref: EHDAA:4677 xref: EMAPA:17813 xref: FMA:6191 xref: GAID:848 xref: MA:0001170 xref: MESH:D010791 xref: NCIT:C52813 xref: SCTID:280344009 xref: UMLS:C0031774 {source="ncithesaurus:Phrenic_Nerve"} xref: VHOG:0000728 xref: Wikipedia:Phrenic_nerve is_a: UBERON:0003443 ! thoracic cavity nerve intersection_of: UBERON:0001021 ! nerve intersection_of: RO:0002134 UBERON:0001103 ! innervates diaphragm relationship: RO:0002134 UBERON:0001103 ! innervates diaphragm relationship: RO:0002380 UBERON:0000962 ! branching part of nerve of cervical vertebra property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/3/3c/Gray806.png" xsd:anyURI [Term] id: UBERON:0001891 name: midbrain namespace: uberon def: "The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles)[GO]." [GO:0030901] xref: AAO:0010149 xref: BAMS:MES xref: BIRNLEX:1667 xref: BM:MB xref: BTO:0000138 xref: CALOHA:TS-0630 xref: DHBA:10648 xref: DMBA:16649 xref: EFO:0000919 xref: EHDAA2:0001162 xref: EHDAA:3694 xref: EMAPA:16974 xref: EV:0100242 xref: FMA:61993 xref: HBA:9001 xref: MA:0000207 xref: MAT:0000106 xref: MBA:313 xref: MESH:D008636 xref: MIAA:0000106 xref: NCIT:C12510 xref: neuronames:462 {source="BIRNLEX:1667"} xref: RETIRED_EHDAA2:0001104 xref: SCTID:279099009 xref: TAO:0000128 xref: UMLS:C0025462 {source="BIRNLEX:1667", source="ncithesaurus:Mesencephalon"} xref: VHOG:0000069 xref: Wikipedia:Midbrain xref: XAO:0000014 xref: ZFA:0000128 is_a: UBERON:0002616 ! regional part of brain is_a: UBERON:0010314 ! structure with developmental contribution from neural crest relationship: RO:0002254 UBERON:0003849 ! has developmental contribution from mesencephalic neural crest relationship: RO:0002433 UBERON:0000955 ! contributes to morphology of brain relationship: RO:0002495 UBERON:0009616 {source="Bgee:AN"} ! immediate transformation of presumptive midbrain property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/f/f9/Human_brain_inferior_view_description.JPG" xsd:anyURI [Term] id: UBERON:0001892 name: rhombomere namespace: uberon def: "A segment of the developing hindbrain[ZFA]. In the vertebrate embryo, a rhombomere is a transiently divided segment of the developing neural tube, within the hindbrain region (a neuromere) in the area that will eventually become the rhombencephalon. The rhombomeres appear as a series of slightly constricted swellings in the neural tube, caudal to the cephalic flexure.[WP]." [Wikipedia:Rhombomere, ZFIN:curator] synonym: "hindbrain neuromere" EXACT [] synonym: "rhombomere" EXACT [] xref: DHBA:12664 xref: EFO:0003617 xref: EMAPA:16148 xref: FMA:295666 xref: MAT:0000272 xref: MIAA:0000272 xref: RETIRED_EHDAA2:0000669 xref: TAO:0001064 xref: VHOG:0000672 xref: Wikipedia:Rhombomere xref: XAO:0004079 xref: ZFA:0001064 is_a: UBERON:0004731 ! neuromere intersection_of: UBERON:0004731 ! neuromere intersection_of: BFO:0000050 UBERON:0007277 ! part of presumptive hindbrain relationship: BFO:0000050 UBERON:0007277 ! part of presumptive hindbrain [Term] id: UBERON:0001895 name: metencephalon namespace: uberon def: "Rostral segment of the hindbrain that has as its parts the pons (where present) and the cerebellum[WP,modified]." [https://github.com/obophenotype/uberon/issues/300, Wikipedia:Metencephalon] synonym: "epencephalon-2" EXACT [FMA:62003] xref: BAMS:Met xref: BIRNLEX:965 xref: BTO:0000673 xref: CALOHA:TS-2029 xref: DHBA:10655 xref: EHDAA2:0001149 xref: EHDAA:5498 xref: EMAPA:17071 xref: FMA:62003 xref: GAID:594 xref: HBA:4833 xref: MA:0000197 xref: MESH:D020540 xref: NCIT:C32741 xref: neuronames:543 {source="BIRNLEX:965"} xref: UMLS:C0376353 {source="BIRNLEX:965"} xref: UMLS:C1516904 {source="ncithesaurus:Epencephalon"} xref: VHOG:0000741 xref: Wikipedia:Metencephalon is_a: UBERON:0004733 ! segmental subdivision of hindbrain relationship: RO:0002433 UBERON:0002028 ! contributes to morphology of hindbrain relationship: RO:0002495 UBERON:0010092 ! immediate transformation of future metencephalon property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/5/54/EmbryonicBrain.svg" xsd:anyURI property_value: x_1.1:contributor https://github.com/cmungall [Term] id: UBERON:0001896 name: medulla oblongata namespace: uberon def: "Organ component of neuraxis that has as its parts the medullary reticular formation, inferior olivary complex and cochlear nuclear complex, among other structures[FMA]. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate[GO]." [FMA:62004, GO:0021550, Wikipedia:Bone_marrow_of_ovary_oblongata] xref: AAO:0010486 xref: BAMS:Md xref: BAMS:MY xref: BIRNLEX:957 xref: BM:Me xref: BTO:0000041 xref: CALOHA:TS-0607 xref: DMBA:17352 xref: EFO:0000924 xref: EHDAA2:0001088 xref: EHDAA:7588 xref: EMAPA:17550 xref: EV:0100275 xref: FMA:62004 xref: GAID:590 xref: MA:0000206 xref: MAT:0000111 xref: MAT:0000367 xref: MBA:354 xref: MESH:D008526 xref: MIAA:0000111 xref: NCIT:C12442 xref: neuronames:698 {source="BIRNLEX:957"} xref: SCTID:279104005 xref: TAO:0000545 xref: UMLS:C0025148 {source="ncithesaurus:Medulla_Oblongata", source="BIRNLEX:957"} xref: UMLS:C1269575 {source="BIRNLEX:957"} xref: VHOG:0000181 xref: Wikipedia:Bone_marrow_of_ovary_oblongata xref: XAO:0003100 xref: ZFA:0000545 is_a: UBERON:0000064 ! organ part is_a: UBERON:0004121 ! ectoderm-derived structure relationship: BFO:0000050 UBERON:0002298 ! part of brainstem relationship: BFO:0000050 UBERON:0005290 ! part of myelencephalon relationship: RO:0002215 GO:0002027 ! capable of regulation of heart rate relationship: RO:0002215 GO:0043576 ! capable of regulation of respiratory gaseous exchange relationship: RO:0002215 GO:0044058 ! capable of regulation of digestive system process property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/6/6b/Illu_pituitary_pineal_glands.jpg" xsd:anyURI [Term] id: UBERON:0001902 name: epithelium of small intestine namespace: uberon def: "An epithelium that is part of a small intestine [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of small bowel" EXACT [OBOL:automatic] synonym: "epithelial tissue of small intestine" EXACT [OBOL:automatic] synonym: "epithelium of small bowel" EXACT [OBOL:automatic] synonym: "mid intestine epithelium" EXACT [ZFA:0005127] synonym: "small bowel epithelial tissue" EXACT [OBOL:automatic] synonym: "small bowel epithelium" EXACT [OBOL:automatic] synonym: "small intestinal epithelium" EXACT [] synonym: "small intestine epithelial tissue" EXACT [OBOL:automatic] synonym: "small intestine epithelium" EXACT [] xref: BTO:0001258 xref: CALOHA:TS-2104 xref: EMAPA:35778 xref: FMA:62017 xref: MA:0001553 xref: SCTID:45480009 xref: TAO:0005127 xref: ZFA:0005127 is_a: UBERON:0001277 ! intestinal epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: BFO:0000050 UBERON:0002108 ! part of small intestine relationship: BFO:0000050 UBERON:0001204 ! part of mucosa of small intestine relationship: BFO:0000051 CL:0000164 {source="FMA"} ! has part enteroendocrine cell [Term] id: UBERON:0001915 name: endothelium of capillary namespace: uberon def: "An endothelium that is part of a capillary [Automatically generated definition]." [OBOL:automatic] synonym: "blood capillary endothelium" EXACT [OBOL:automatic] synonym: "capillary endothelium" EXACT [] synonym: "capillary vessel endothelium" EXACT [OBOL:automatic] synonym: "endothelium of blood capillary" EXACT [OBOL:automatic] synonym: "endothelium of capillary vessel" EXACT [OBOL:automatic] xref: BTO:0004954 xref: CALOHA:TS-0112 xref: EMAPA:36292 xref: FMA:62114 xref: MA:0000711 xref: NCIT:C49215 xref: UMLS:C0006904 {source="ncithesaurus:Capillary_Endothelium"} is_a: UBERON:0008339 ! microvascular endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: BFO:0000050 UBERON:0001982 ! part of capillary relationship: BFO:0000050 UBERON:0001982 ! part of capillary [Term] id: UBERON:0001916 name: endothelium of arteriole namespace: uberon def: "An endothelium that is part of an arteriole [Automatically generated definition]." [OBOL:automatic] synonym: "arteriole endothelium" EXACT [] xref: EMAPA:36286 xref: FMA:62115 xref: MA:0000705 xref: NCIT:C49192 xref: UMLS:C1179024 {source="ncithesaurus:Arteriole_Endothelium"} is_a: UBERON:0004700 ! arterial system endothelium is_a: UBERON:0008339 ! microvascular endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: BFO:0000050 UBERON:0001980 ! part of arteriole relationship: BFO:0000050 UBERON:0001980 ! part of arteriole [Term] id: UBERON:0001917 name: endothelium of artery namespace: uberon def: "An endothelium that is part of an artery [Automatically generated definition]." [OBOL:automatic] synonym: "arterial endothelium" EXACT [] synonym: "artery endothelium" EXACT [] xref: AAO:0011013 xref: BTO:0004757 xref: EMAPA:35148 xref: FMA:62116 xref: MA:0000707 xref: NCIT:C49194 xref: UMLS:C1179025 {source="ncithesaurus:Artery_Endothelium"} xref: VHOG:0001215 xref: XAO:0000357 is_a: UBERON:0003915 ! endothelial tube is_a: UBERON:0004638 ! blood vessel endothelium is_a: UBERON:0004700 ! arterial system endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: BFO:0000050 UBERON:0001637 ! part of artery relationship: BFO:0000050 UBERON:0001637 ! part of artery [Term] id: UBERON:0001918 name: endothelium of venule namespace: uberon def: "An endothelium that is part of a venule [Automatically generated definition]." [OBOL:automatic] synonym: "venule endothelium" EXACT [] xref: EMAPA:36290 xref: FMA:62117 xref: MA:0000716 xref: NCIT:C49319 xref: UMLS:C1179026 {source="ncithesaurus:Venule_Endothelium"} is_a: UBERON:0004701 ! venous system endothelium is_a: UBERON:0008339 ! microvascular endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: BFO:0000050 UBERON:0001979 ! part of venule relationship: BFO:0000050 UBERON:0001979 ! part of venule [Term] id: UBERON:0001919 name: endothelium of vein namespace: uberon def: "An endothelium that is part of a vein [Automatically generated definition]." [OBOL:automatic] synonym: "vein endothelium" EXACT [] synonym: "venous endothelium" EXACT [] xref: AAO:0011110 xref: BTO:0004756 xref: EMAPA:36288 xref: FMA:62118 xref: MA:0000712 xref: NCIT:C49317 xref: UMLS:C1179027 {source="ncithesaurus:Vein_Endothelium"} xref: VHOG:0001216 xref: XAO:0000358 is_a: UBERON:0004638 ! blood vessel endothelium is_a: UBERON:0004701 ! venous system endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: BFO:0000050 UBERON:0001638 ! part of vein relationship: BFO:0000050 UBERON:0001638 ! part of vein [Term] id: UBERON:0001943 name: midbrain tegmentum namespace: uberon def: "Ventral part of the midbrain, separated from the hindbrain by the isthmus[ISBN:0471888893]. Subdivision of the midbrain lying anterior to the tectum and posterior to the substantia nigra and cerebral peduncle[FMA] The part of the midbrain extending from the substantia nigra to the cerebral aqueduct in a horizontal section of the midbrain. It forms the floor of the midbrain that surrounds the cerebral aqueduct[WP]." [FMA:FMA, ISBN:0471888893, Wikipedia:Midbrain_tegmentum] synonym: "tegmentum of midbrain" EXACT [] xref: BAMS:MTg xref: BIRNLEX:1200 xref: BTO:0003388 xref: DHBA:12195 xref: EFO:0000921 xref: EHDAA2:0004475 xref: EMAPA:18215 xref: FMA:62393 xref: HBA:9002 xref: MA:0000212 xref: MAT:0000452 xref: neuronames:491 {source="BIRNLEX:1200"} xref: SCTID:362392007 xref: TAO:0000160 xref: UMLS:C0039441 {source="BIRNLEX:1200"} xref: VHOG:0001367 xref: Wikipedia:Midbrain_tegmentum xref: XAO:0004271 xref: ZFA:0000160 is_a: UBERON:0002616 ! regional part of brain relationship: BFO:0000050 UBERON:0001891 ! part of midbrain relationship: BFO:0000050 UBERON:0002298 ! part of brainstem relationship: RO:0002202 UBERON:0010285 {source="ZFA"} ! develops from midbrain basal plate property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/b/b6/Gray712.png" xsd:anyURI [Term] id: UBERON:0001948 name: regional part of spinal cord namespace: uberon def: "A multi-tissue structure that is part of a spinal cord." [OBOL:automatic] xref: BIRNLEX:1496 xref: NCIT:C33969 xref: SCTID:244437008 xref: UMLS:C1268166 {source="ncithesaurus:Spinal_Cord_Part"} is_a: UBERON:0000073 ! regional part of nervous system is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: BFO:0000050 UBERON:0002240 ! part of spinal cord relationship: BFO:0000050 UBERON:0002240 ! part of spinal cord [Term] id: UBERON:0001968 name: semen namespace: uberon def: "Organism substance that is composed of sperm cells suspended in seminal fluid." [http://orcid.org/0000-0002-6601-2165] xref: BTO:0001230 xref: CALOHA:TS-0917 xref: EMAPA:31488 xref: FMA:62966 xref: GAID:1169 xref: MA:0002522 xref: MESH:D012661 xref: NCIT:C13277 xref: NCIT:C13713 xref: UMLS:C1518159 {source="ncithesaurus:Male_Genital_System_Fluid_or_Secretion"} xref: UMLS:C2756969 {source="ncithesaurus:Semen"} xref: Wikipedia:Semen is_a: UBERON:0000463 ! organism substance relationship: BFO:0000051 CL:0000019 ! has part sperm relationship: BFO:0000051 UBERON:0006530 ! has part seminal fluid relationship: RO:0002353 GO:0042713 ! output of sperm ejaculation property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/4/40/Human_semen_in_petri_dish2.jpg" xsd:anyURI [Term] id: UBERON:0001969 name: blood plasma namespace: uberon def: "The liquid component of blood, in which erythrocytes are suspended." [http://orcid.org/0000-0002-6601-2165] synonym: "blood plasm" EXACT [] synonym: "portion of blood plasma" EXACT [] xref: BTO:0000131 xref: CALOHA:TS-0800 xref: EFO:0001905 xref: EMAPA:35690 xref: FMA:62970 xref: GAID:1178 xref: MA:0002501 xref: MAT:0000052 xref: MESH:D010949 xref: MIAA:0000052 xref: NCIT:C13356 xref: UMLS:C0032105 {source="ncithesaurus:Plasma"} xref: Wikipedia:Blood_plasma is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000179 ! haemolymphatic fluid intersection_of: UBERON:0000463 ! organism substance intersection_of: BFO:0000050 UBERON:0000178 ! part of blood intersection_of: BFO:0000051 GO:0005577 ! has part fibrinogen complex intersection_of: RO:0000086 PATO:0001548 ! has quality quality of a liquid intersection_of: RO:0002221 CL:0000232 ! surrounds erythrocyte relationship: BFO:0000050 UBERON:0000178 ! part of blood relationship: BFO:0000051 GO:0005577 ! has part fibrinogen complex relationship: RO:0002221 CL:0000232 ! surrounds erythrocyte [Term] id: UBERON:0001970 name: bile namespace: uberon def: "Vital aqueous secretion of the liver that is formed by hepatocytes and modified down stream by absorptive and secretory properties of the bile duct epithelium." [DOI:10.1002/cphy.c120027, Wikipedia:Bile] xref: BTO:0000121 xref: CALOHA:TS-1172 xref: ENVO:02000023 xref: FMA:62971 xref: GAID:1157 xref: galen:Bile xref: MA:0002513 xref: MESH:D001646 xref: NCIT:C13192 xref: UMLS:C0005388 {source="ncithesaurus:Bile"} xref: Wikipedia:Bile xref: ZFA:0005857 is_a: UBERON:0000456 ! secretion of exocrine gland is_a: UBERON:0006314 ! bodily fluid intersection_of: UBERON:0000456 ! secretion of exocrine gland intersection_of: RO:0003001 UBERON:0002107 ! produced by liver relationship: BFO:0000051 CHEBI:16990 ! has part bilirubin IXalpha relationship: BFO:0000051 CHEBI:22868 ! has part bile salt relationship: BFO:0000051 CHEBI:36277 ! has part bile acid salt relationship: RO:0000086 PATO:0001735 ! has quality liquid configuration relationship: RO:0002216 GO:0007586 ! capable of part of digestion relationship: RO:0003001 UBERON:0002107 ! produced by liver [Term] id: UBERON:0001971 name: gastric juice namespace: uberon synonym: "stomach secretion" EXACT [] xref: BTO:0000501 xref: FMA:62972 xref: GAID:1160 xref: galen:GastricJuice xref: MA:0002519 xref: MESH:D005750 xref: NCIT:C32661 xref: UMLS:C0017133 {source="ncithesaurus:Gastric_Secretion"} xref: Wikipedia:Gastric_juice is_a: UBERON:0000456 ! secretion of exocrine gland intersection_of: UBERON:0000456 ! secretion of exocrine gland intersection_of: RO:0003001 UBERON:0011953 ! produced by stomach glandular region relationship: RO:0003001 UBERON:0011953 ! produced by stomach glandular region [Term] id: UBERON:0001972 name: submucosa of esophagus namespace: uberon def: "A submucosa that is part of a esophagus [Automatically generated definition]." [OBOL:automatic] synonym: "esophageal submucosa" EXACT [] synonym: "esophagus submucosa" EXACT [] synonym: "gullet submucosa" EXACT [OBOL:automatic] synonym: "oesophagus submucosa" EXACT [OBOL:automatic] synonym: "submucosa of esophagus" EXACT [] synonym: "submucosa of gullet" EXACT [OBOL:automatic] synonym: "submucosa of oesophagus" EXACT [OBOL:automatic] synonym: "tela submucosa of esophagus" EXACT [] xref: BTO:0002109 xref: EMAPA:35325 xref: FMA:62997 xref: MA:0002724 xref: SCTID:362128009 is_a: UBERON:0018257 ! submucosa of digestive tract intersection_of: UBERON:0000009 ! submucosa intersection_of: BFO:0000050 UBERON:0001043 ! part of esophagus relationship: BFO:0000050 UBERON:0001096 ! part of wall of esophagus [Term] id: UBERON:0001974 name: lamina propria of esophagus namespace: uberon def: "A lamina propria that is part of a esophagus [Automatically generated definition]." [OBOL:automatic] synonym: "esophagus lamina propria" EXACT [] synonym: "esophagus lamina propria mucosa" EXACT [OBOL:automatic] synonym: "esophagus lamina propria mucosae" EXACT [OBOL:automatic] synonym: "gullet lamina propria" EXACT [OBOL:automatic] synonym: "gullet lamina propria mucosa" EXACT [OBOL:automatic] synonym: "gullet lamina propria mucosae" EXACT [OBOL:automatic] synonym: "lamina propria mucosa of esophagus" EXACT [OBOL:automatic] synonym: "lamina propria mucosa of gullet" EXACT [OBOL:automatic] synonym: "lamina propria mucosa of oesophagus" EXACT [OBOL:automatic] synonym: "lamina propria mucosae of esophagus" EXACT [] synonym: "lamina propria mucosae of gullet" EXACT [OBOL:automatic] synonym: "lamina propria mucosae of oesophagus" EXACT [OBOL:automatic] synonym: "lamina propria of gullet" EXACT [OBOL:automatic] synonym: "lamina propria of oesophagus" EXACT [OBOL:automatic] synonym: "oesophagus lamina propria mucosa" EXACT [OBOL:automatic] synonym: "oesophagus lamina propria mucosae" EXACT [OBOL:automatic] xref: EMAPA:26987 xref: FMA:63050 xref: MA:0001568 xref: NCIT:C49223 xref: UMLS:C1707949 {source="ncithesaurus:Esophageal_Lamina_Propria"} is_a: UBERON:0000030 ! lamina propria intersection_of: UBERON:0000030 ! lamina propria intersection_of: BFO:0000050 UBERON:0001043 ! part of esophagus relationship: BFO:0000050 UBERON:0002469 {source="FMA"} ! part of esophagus mucosa [Term] id: UBERON:0001975 name: serosa of esophagus namespace: uberon def: "A serous membrane that is part of a esophagus [Automatically generated definition]." [OBOL:automatic] synonym: "esophagus serosa" EXACT [] synonym: "esophagus serous membrane" EXACT [OBOL:automatic] synonym: "gullet serosa" EXACT [OBOL:automatic] synonym: "gullet serous membrane" EXACT [OBOL:automatic] synonym: "oesophagus serous membrane" EXACT [OBOL:automatic] synonym: "serosa of abdominal part of esophagus" EXACT [] synonym: "serosa of gullet" EXACT [OBOL:automatic] synonym: "serosa of oesophagus" EXACT [] synonym: "serous coat of oesophagus" EXACT [] synonym: "serous membrane of esophagus" EXACT [OBOL:automatic] synonym: "serous membrane of gullet" EXACT [OBOL:automatic] synonym: "serous membrane of oesophagus" EXACT [OBOL:automatic] xref: EMAPA:35322 xref: FMA:63057 xref: MA:0001571 is_a: UBERON:0000042 ! serous membrane intersection_of: UBERON:0000042 ! serous membrane intersection_of: BFO:0000050 UBERON:0001043 ! part of esophagus relationship: BFO:0000050 UBERON:0001096 ! part of wall of esophagus [Term] id: UBERON:0001976 name: epithelium of esophagus namespace: uberon def: "The epithelial layer that lines the luminal space of the esophagus." [ISBN:0-683-40008-8, MP:0000468] synonym: "epithelial tissue of esophagus" EXACT [OBOL:automatic] synonym: "epithelial tissue of gullet" EXACT [OBOL:automatic] synonym: "epithelial tissue of oesophagus" EXACT [OBOL:automatic] synonym: "epithelium of gullet" EXACT [OBOL:automatic] synonym: "epithelium of oesophagus" EXACT [OBOL:automatic] synonym: "esophageal epithelium" EXACT [] synonym: "esophagus epithelial tissue" EXACT [OBOL:automatic] synonym: "esophagus epithelium" EXACT [] synonym: "gullet epithelial tissue" EXACT [OBOL:automatic] synonym: "gullet epithelium" EXACT [OBOL:automatic] synonym: "oesophagus epithelial tissue" EXACT [OBOL:automatic] xref: BTO:0001578 xref: CALOHA:TS-0698 xref: EFO:0003041 xref: EHDAA2:0001287 xref: EMAPA:16835 xref: FMA:63063 xref: MA:0001565 xref: NCIT:C49221 xref: TAO:0001499 xref: UMLS:C1179544 {source="ncithesaurus:Esophageal_Epithelium"} xref: ZFA:0001499 is_a: UBERON:0003350 ! epithelium of mucosa is_a: UBERON:0003929 ! digestive tract epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: BFO:0000050 UBERON:0001043 ! part of esophagus relationship: BFO:0000050 UBERON:0002469 {source="FMA"} ! part of esophagus mucosa relationship: RO:0002433 UBERON:0001043 ! contributes to morphology of esophagus [Term] id: UBERON:0001978 name: parenchyma of pancreas namespace: uberon synonym: "pancreas parenchyma" EXACT [] synonym: "pancreatic parenchyma" EXACT [] xref: EMAPA:32925 xref: FMA:63120 xref: MA:0000724 xref: SCTID:371401008 xref: VHOG:0001430 is_a: UBERON:0000353 ! parenchyma intersection_of: UBERON:0000353 ! parenchyma intersection_of: BFO:0000050 UBERON:0001264 ! part of pancreas relationship: BFO:0000050 UBERON:0001264 ! part of pancreas [Term] id: UBERON:0001979 name: venule namespace: uberon def: "One of the minute vessels that collect deoxygenated blood from the capillary plexuses returns it to the veins." [MESH:A07.231.432.952, MP:0004125] xref: BTO:0002626 xref: EMAPA:35917 xref: FMA:63130 xref: MA:0000071 xref: MESH:D014699 xref: NCIT:C12818 xref: SCTID:341687009 xref: TAO:0005315 xref: UMLS:C0042520 {source="ncithesaurus:Venule"} xref: VHOG:0001765 xref: Wikipedia:Venule xref: ZFA:0005315 is_a: UBERON:0003920 ! venous blood vessel is_a: UBERON:8410081 ! blood microvessel relationship: RO:0002176 UBERON:0001638 ! connects vein relationship: RO:0002176 UBERON:0001982 ! connects capillary property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/d/da/Illu_capillary.jpg" xsd:anyURI [Term] id: UBERON:0001980 name: arteriole namespace: uberon def: "The smallest division of the artery located between the muscular arteries and the capillaries[GO]." [GO:0014830] xref: AAO:0010253 xref: BTO:0001997 xref: EMAPA:35146 xref: FMA:63182 xref: MA:0000063 xref: MESH:D001160 xref: NCIT:C12672 xref: SCTID:337724002 xref: TAO:0002138 xref: UMLS:C0003847 {source="ncithesaurus:Arteriole"} xref: VHOG:0001763 xref: Wikipedia:Arteriole xref: ZFA:0005255 is_a: UBERON:0003509 {source="MA"} ! arterial blood vessel is_a: UBERON:8410081 ! blood microvessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: RO:0002176 UBERON:0001637 ! connects artery intersection_of: RO:0002176 UBERON:0001982 ! connects capillary relationship: RO:0002176 UBERON:0001637 ! connects artery relationship: RO:0002176 UBERON:0001982 ! connects capillary relationship: RO:0002433 UBERON:0001637 ! contributes to morphology of artery property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/d/da/Illu_capillary.jpg" xsd:anyURI [Term] id: UBERON:0001981 name: blood vessel namespace: uberon def: "A vessel through which blood circulates in the body." [BTO:0001102, Wikipedia:Blood_vessel] synonym: "region of vascular tree organ" EXACT [FMA:50722] synonym: "vascular tree organ region" EXACT [FMA:50722] xref: AAO:0011004 xref: AEO:0000207 xref: BTO:0001102 xref: CALOHA:TS-0080 xref: EFO:0000817 xref: EHDAA2:0003252 xref: EHDAA:240 xref: EMAPA:32743 xref: EMAPA:35993 xref: FMA:50722 xref: FMA:63183 xref: GAID:169 xref: MA:0000060 xref: MAT:0000393 xref: MESH:D001808 xref: NCIT:C12679 xref: NLXANAT:090901 xref: SCTID:361097006 xref: TAO:0002137 xref: UMLS:C0005847 {source="ncithesaurus:Blood_Vessel"} xref: VHOG:0001250 xref: Wikipedia:Blood_vessel xref: XAO:0001011 xref: ZFA:0005314 is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000055 ! vessel is_a: UBERON:0004120 ! mesoderm-derived structure relationship: BFO:0000050 UBERON:0004537 ! part of blood vasculature relationship: BFO:0000051 CL:0000071 {source="AEO"} ! has part blood vessel endothelial cell relationship: BFO:0000051 UBERON:0007500 {source="EHDAA2"} ! has part epithelial tube open at both ends relationship: channel_for UBERON:0000178 ! blood relationship: RO:0000086 PATO:0002045 ! has quality dendritic relationship: RO:0002202 UBERON:0004872 ! develops from splanchnic layer of lateral plate mesoderm relationship: RO:0002202 UBERON:0006965 {source="GO:0072360"} ! develops from vascular cord relationship: RO:0002216 GO:0008015 ! capable of part of blood circulation property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/2/29/Circulatory_System_en.svg" xsd:anyURI [Term] id: UBERON:0001982 name: capillary namespace: uberon def: "Any of the smallest blood vessels connecting arterioles with venules." [https://github.com/obophenotype/uberon/issues/137, ISBN:0073040584, Wikipedia:Capillary] synonym: "blood capillary" EXACT [] synonym: "capillary vessel" EXACT [] xref: AAO:0010252 xref: BTO:0002045 xref: CALOHA:TS-2006 xref: EFO:0001906 xref: EMAPA:35198 xref: EV:0100035 xref: FMA:63194 xref: MA:0000065 xref: MESH:D002196 xref: NCIT:C12685 xref: NLXANAT:090902 xref: TAO:0005250 xref: UMLS:C0935624 {source="ncithesaurus:Capillary"} xref: VHOG:0001253 xref: Wikipedia:Capillary xref: XAO:0000116 xref: ZFA:0005250 is_a: UBERON:8410081 ! blood microvessel intersection_of: UBERON:8410081 ! blood microvessel intersection_of: RO:0002176 UBERON:0001979 ! connects venule intersection_of: RO:0002176 UBERON:0001980 ! connects arteriole relationship: RO:0002176 UBERON:0001979 ! connects venule relationship: RO:0002176 UBERON:0001980 ! connects arteriole property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/2/2f/A_red_blood_cell_in_a_capillary,_pancreatic_tissue_-_TEM.jpg" xsd:anyURI [Term] id: UBERON:0001985 name: corneal endothelium namespace: uberon def: "A monolayer of specialized, flattened, mitochondria-rich cells that lines the posterior surface of the cornea and faces the anterior chamber of the eye[WP]." [Wikipedia:Corneal_endothelium] synonym: "cornea endothelium" EXACT [OBOL:automatic] synonym: "endothelium of cornea" EXACT [OBOL:automatic] xref: CALOHA:TS-0172 xref: EMAPA:35935 xref: FMA:63882 xref: GAID:891 xref: MA:0001242 xref: MESH:D004728 xref: NCIT:C12707 xref: SCTID:368827009 xref: TAO:0002186 xref: UMLS:C0014259 {source="ncithesaurus:Corneal_Endothelium"} xref: Wikipedia:Corneal_endothelium xref: ZFA:0001687 is_a: UBERON:0001986 ! endothelium is_a: UBERON:0010313 ! neural crest-derived structure is_a: UBERON:0015808 ! eye epithelium intersection_of: UBERON:0001986 ! endothelium intersection_of: BFO:0000050 UBERON:0000964 ! part of cornea relationship: BFO:0000050 UBERON:0000964 ! part of cornea relationship: RO:0002220 UBERON:0001766 ! adjacent to anterior chamber of eyeball relationship: RO:0002433 UBERON:0000964 ! contributes to morphology of cornea property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/6/66/Gray871.png" xsd:anyURI [Term] id: UBERON:0001986 name: endothelium namespace: uberon def: "A layer of epithelium that lines the heart, blood vessels (endothelium, vascular), lymph vessels (endothelium, lymphatic), and the serous cavities of the body[MESH]. Simple squamous epithelium which lines blood and lymphatic vessels and the heart[FMA]." [FMA:63916, https://github.com/obophenotype/uberon/issues/225, MESH:A10.272.491] xref: BTO:0000393 xref: CALOHA:TS-0278 xref: EFO:0002548 xref: FMA:63916 xref: GAID:520 xref: galen:Endothelium xref: MESH:D004727 xref: NCIT:C12481 xref: SCTID:27168002 xref: UMLS:C0014257 {source="ncithesaurus:Endothelium"} is_a: UBERON:0000487 {source="FMA-text-def", source="https://github.com/obophenotype/uberon/issues/225"} ! simple squamous epithelium is_a: UBERON:0012275 ! meso-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: RO:0002473 CL:0000115 ! composed primarily of endothelial cell relationship: RO:0002160 NCBITaxon:7742 ! only in taxon Vertebrata relationship: RO:0002473 CL:0000115 ! composed primarily of endothelial cell [Term] id: UBERON:0001987 name: placenta namespace: uberon def: "Organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin[GO]. The fetal portion of the placenta is known as the villous chorion. The maternal portion is known as the decidua basalis. The two portions are held together by anchoring villi that are anchored to the decidua basalis by the cytotrophoblastic shell." [http://www.med.umich.edu/lrc/coursepages/m1/embryology/embryo/06placenta.htm, Wikipedia:Placenta] synonym: "allantoic placenta" EXACT [ISBN:0073040584] synonym: "eutherian placenta" EXACT [] xref: BTO:0001078 xref: CALOHA:TS-0799 xref: EFO:0001407 xref: EMAPA:35689 xref: EV:0100119 xref: FMA:63934 xref: GAID:379 xref: MA:0000386 xref: MAT:0000279 xref: MESH:D010920 xref: MIAA:0000279 xref: NCIT:C13272 xref: SCTID:181455002 xref: UMLS:C0032043 {source="ncithesaurus:Placenta"} xref: VHOG:0001266 xref: Wikipedia:Placenta is_a: UBERON:0000062 ! organ is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005156 ! reproductive structure relationship: BFO:0000050 UBERON:0000474 ! part of female reproductive system relationship: BFO:0000050 UBERON:0016887 ! part of entire extraembryonic component relationship: RO:0002160 NCBITaxon:32525 {source="https://github.com/obophenotype/uberon/issues/1376"} ! only in taxon Theria relationship: RO:0002202 UBERON:0000995 {source="ISBN:0073040584"} ! develops from uterus relationship: RO:0002202 UBERON:0003124 {source="Wikipedia"} ! develops from chorion membrane relationship: RO:0002202 UBERON:0004340 {source="ISBN:0073040584"} ! develops from allantois property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/6/66/Placenta.jpg" xsd:anyURI property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/f/f1/Placenta.svg" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Placenta.glb" xsd:anyURI [Term] id: UBERON:0001988 name: feces namespace: uberon def: "Portion of semisolid bodily waste discharged through the anus[MW,modified]." [http://www.merriam-webster.com/dictionary/feces, Wikipedia:Feces] synonym: "faeces" EXACT [] synonym: "fecal material" EXACT [] synonym: "fecal matter" EXACT [] synonym: "piece of shit" EXACT [PMID:23285307] synonym: "portion of excrement" EXACT [] synonym: "portion of faeces" EXACT [] synonym: "portion of fecal material" EXACT [] synonym: "portion of fecal matter" EXACT [] synonym: "portion of feces" EXACT [] synonym: "stool" EXACT [] xref: BTO:0000440 xref: CALOHA:TS-2345 xref: ENVO:00002003 xref: FMA:64183 xref: GAID:1199 xref: galen:Feces xref: MA:0002509 xref: MAT:0000053 xref: MESH:D005243 xref: MIAA:0000053 xref: NCIT:C13234 xref: UMLS:C0015733 {source="ncithesaurus:Feces"} xref: Wikipedia:Feces is_a: UBERON:0000174 ! excreta intersection_of: UBERON:0000174 ! excreta intersection_of: RO:0002353 GO:0030421 ! output of defecation relationship: RO:0002353 GO:0030421 ! output of defecation [Term] id: UBERON:0002012 name: pulmonary artery namespace: uberon def: "An artery that carries deoxygenated blood from heart to the lungs. They are the only arteries (other than umbilical arteries in the fetus) that carry deoxygenated blood.." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Pulmonary_artery] synonym: "pulmonary arterial tree" EXACT [FMA:66326] synonym: "pulmonary arterial tree organ part" EXACT [FMA:66326] xref: AAO:0010221 xref: BTO:0000778 xref: CALOHA:TS-0839 xref: EFO:0001399 xref: EHDAA2:0001575 xref: EHDAA:4351 xref: EMAPA:17008 xref: FMA:66326 xref: GAID:505 xref: galen:PulmonaryArtery xref: MA:0002031 xref: MESH:D011651 xref: NCIT:C12774 xref: SCTID:181380003 xref: UMLS:C0034052 {source="ncithesaurus:Pulmonary_Artery"} xref: VHOG:0000982 xref: Wikipedia:Pulmonary_artery xref: XAO:0004162 is_a: UBERON:0001637 ! artery is_a: UBERON:0013768 ! great vessel of heart intersection_of: UBERON:0001637 ! artery intersection_of: BFO:0000050 UBERON:0008886 ! part of pulmonary vascular system intersection_of: RO:0002178 UBERON:0002048 ! supplies lung disjoint_from: UBERON:0004573 ! systemic artery relationship: BFO:0000050 RO:0002577 ! part of system relationship: BFO:0000050 UBERON:0008886 ! part of pulmonary vascular system relationship: RO:0002150 UBERON:0002333 ! continuous with pulmonary trunk relationship: RO:0002178 UBERON:0002048 ! supplies lung relationship: RO:0002202 UBERON:0002061 {source="Wikipedia"} ! develops from truncus arteriosus relationship: RO:0002202 UBERON:0003123 {source="EHDAA2", source="XAO"} ! develops from pharyngeal arch artery 6 relationship: RO:0002202 UBERON:0005339 {source="EHDAA2"} ! develops from outflow tract pulmonary component property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/d/db/Alveoli_diagram.png" xsd:anyURI [Term] id: UBERON:0002015 name: kidney capsule namespace: uberon def: "The tough fibrous layer surrounding the kidney which is covered in a thick layer of perirenal adipose tissue that functions to provide some protection from trauma and damage." [MGI:anna, MP:0011383] synonym: "capsule of kidney" EXACT [] synonym: "fibrous capsule of kidney" EXACT [FMA:66610] synonym: "renal capsule" EXACT [GO:0072127] xref: EMAPA:18679 xref: FMA:66610 xref: galen:CapsuleOfKidney xref: MA:0000370 xref: NCIT:C12885 xref: SCTID:243657006 xref: UMLS:C0227637 {source="ncithesaurus:Renal_Capsule"} xref: Wikipedia:Kidney_capsule is_a: UBERON:0003567 ! abdomen connective tissue is_a: UBERON:0011824 ! fibrous connective tissue intersection_of: UBERON:0011824 ! fibrous connective tissue intersection_of: RO:0002007 UBERON:0002113 ! bounding layer of kidney relationship: RO:0002007 UBERON:0002113 ! bounding layer of kidney relationship: RO:0002433 UBERON:0002113 ! contributes to morphology of kidney property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Kidney_L.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Kidney_R.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Kidney_L.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Kidney_R.glb" xsd:anyURI property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/6/69/Illu_kidney.jpg" xsd:anyURI [Term] id: UBERON:0002016 name: pulmonary vein namespace: uberon def: "Pulmonary veins are blood vessels that transport blood from the lungs to the heart[GO]." [GO:0060577] synonym: "pulmonary venous tree organ part" EXACT [] xref: AAO:0010521 xref: BTO:0001799 xref: CALOHA:TS-0840 xref: EHDAA2:0001579 xref: EHDAA:2629 xref: EMAPA:18645 xref: FMA:66643 xref: GAID:543 xref: galen:PulmonaryVein xref: MA:0002206 xref: MESH:D011667 xref: NCIT:C12776 xref: SCTID:430160002 xref: UMLS:C0034090 {source="ncithesaurus:Pulmonary_Vein"} xref: VHOG:0001133 xref: Wikipedia:Pulmonary_vein xref: XAO:0000394 is_a: UBERON:0001638 ! vein is_a: UBERON:0013768 ! great vessel of heart intersection_of: UBERON:0001638 ! vein intersection_of: RO:0002179 UBERON:0002048 ! drains lung relationship: BFO:0000050 RO:0002577 ! part of system relationship: BFO:0000050 UBERON:0008886 ! part of pulmonary vascular system relationship: RO:0002170 UBERON:0002079 ! connected to left cardiac atrium relationship: RO:0002179 UBERON:0002048 ! drains lung relationship: RO:0002202 UBERON:0002061 ! develops from truncus arteriosus property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/d/db/Alveoli_diagram.png" xsd:anyURI [Term] id: UBERON:0002017 name: portal vein namespace: uberon def: "A vein that conducts blood from the digestive organs, spleen, pancreas, and gallbladder to the liver[BTO]." [BTO:0001792] synonym: "portal venous tree organ part" EXACT [FMA:66645] xref: BTO:0001792 xref: CALOHA:TS-0814 xref: EHDAA2:0001485 xref: EHDAA:6510 xref: EMAPA:17349 xref: FMA:66645 xref: GAID:540 xref: galen:PortalVein xref: MA:0002198 xref: MESH:D011169 xref: NCIT:C33343 xref: SCTID:362064007 xref: UMLS:C0032718 {source="ncithesaurus:Portal_Vein"} xref: VHOG:0000656 xref: XAO:0000392 is_a: UBERON:0001638 {source="FMA"} ! vein relationship: BFO:0000050 UBERON:0005806 ! part of portal system property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/3/33/Gray591.png" xsd:anyURI [Term] id: UBERON:0002020 name: gray matter namespace: uberon def: "A nervous system structure composed primarily of nerve cell bodies (somas). May also include dendrites and the initial unmyelinated portion of axons." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Gray_matter] synonym: "gray matter" EXACT [] synonym: "gray matter of neuraxis" EXACT [FMA:67242] synonym: "grey matter" EXACT [] synonym: "grey matter of neuraxis" EXACT [] synonym: "grey substance" EXACT [] synonym: "neuronal grey matter" EXACT [AEO:0001012] xref: AEO:0001012 xref: EHDAA2:0003136 xref: EHDAA2_RETIRED:0004658 xref: EMAPA:37596 {source="MA:th"} xref: FMA:67242 xref: HBA:4006 xref: MA:0001112 xref: NCIT:C32695 xref: neuronames:2869 xref: TAO:0002197 xref: UMLS:C0018220 {source="ncithesaurus:Gray_Matter"} xref: VHOG:0001768 xref: Wikipedia:Gray_matter xref: ZFA:0001681 is_a: UBERON:0011215 ! central nervous system cell part cluster relationship: RO:0002473 GO:0043025 ! composed primarily of neuronal cell body property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/d/d2/Spinal_nerve.svg" xsd:anyURI [Term] id: UBERON:0002028 name: hindbrain namespace: uberon def: "The most posterior of the three principal regions of the brain. In mammals and birds the hindbrain is divided into a rostral metencephalon and a caudal myelencephalon. In zebrafish, with the exception of the cerebellum, the ventral remainder of the metencephalon can be separated only arbitrarily from the more caudal myelencephalic portion of the medulla oblongata (From: Neuroanatomy of the Zebrafish Brain)[ZFA]. Organ component of neuraxis that has as its parts the pons, cerebellum and medulla oblongata[FMA]." [Wikipedia:Rhombencephalon, ZFA:0000029, ZFIN:curator] xref: AAO:0010150 xref: BAMS:HB xref: BIRNLEX:942 xref: BTO:0000672 xref: CALOHA:TS-0457 xref: DHBA:10653 xref: DMBA:16808 xref: EFO:0000923 xref: EHDAA2:0000746 xref: EHDAA:3514 xref: EHDAA:6487 xref: EMAPA:16916 xref: FMA:67687 xref: MA:0000195 xref: MAT:0000107 xref: MBA:1065 xref: MESH:D012249 xref: MIAA:0000107 xref: NCIT:C40336 xref: neuronames:540 {source="BIRNLEX:942"} xref: SCTID:303456008 xref: TAO:0000029 xref: UMLS:C0035507 {source="ncithesaurus:Hind-Brain", source="BIRNLEX:942"} xref: UMLS:C1522180 {source="BIRNLEX:942"} xref: VHOG:0000070 xref: Wikipedia:Rhombencephalon xref: XAO:0000015 xref: ZFA:0000029 is_a: UBERON:0002616 ! regional part of brain relationship: RO:0002131 UBERON:0002298 ! overlaps brainstem relationship: RO:0002160 NCBITaxon:89593 ! only in taxon Craniata relationship: RO:0002433 UBERON:0000955 ! contributes to morphology of brain relationship: RO:0002495 UBERON:0007277 {source="Bgee:AN"} ! immediate transformation of presumptive hindbrain property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/5/54/EmbryonicBrain.svg" xsd:anyURI [Term] id: UBERON:0002029 name: epithelium of gall bladder namespace: uberon def: "The simple columnar epithelial lining of the gall bladder." [MP:0009492] synonym: "epithelial tissue of gall bladder" EXACT [OBOL:automatic] synonym: "epithelial tissue of gallbladder" EXACT [OBOL:automatic] synonym: "epithelium of gallbladder" EXACT [OBOL:automatic] synonym: "gall bladder epithelial tissue" EXACT [OBOL:automatic] synonym: "gall bladder epithelium" EXACT [] synonym: "gallbladder epithelial tissue" EXACT [OBOL:automatic] synonym: "gallbladder epithelium" EXACT [OBOL:automatic] xref: BTO:0001449 xref: CALOHA:TS-1304 xref: EMAPA:35370 xref: FMA:67711 xref: MA:0001632 xref: NCIT:C49227 xref: UMLS:C1180206 {source="ncithesaurus:Gallbladder_Epithelium"} is_a: UBERON:0000485 ! simple columnar epithelium is_a: UBERON:0005911 ! endo-epithelium is_a: UBERON:0034932 ! epithelium of biliary system intersection_of: UBERON:0000483 ! epithelium intersection_of: BFO:0000050 UBERON:0002110 ! part of gallbladder relationship: BFO:0000050 UBERON:0002110 ! part of gallbladder relationship: RO:0002433 UBERON:0002110 ! contributes to morphology of gallbladder [Term] id: UBERON:0002036 name: striated muscle tissue namespace: uberon def: "Muscle tissue that contains fibers that are divided by transverse bands into striations." [CL:0000737, GOC:dph, GOC:mtg_muscle] synonym: "striated muscle" EXACT [] xref: AAO:0010762 xref: AEO:0000140 xref: CALOHA:TS-2047 xref: EHDAA2:0003140 xref: EMAPA:36390 xref: FMA:67905 xref: galen:StriatedMuscle xref: MA:0002438 xref: NCIT:C12436 xref: UMLS:C1331262 {source="ncithesaurus:Striated_Muscle_Tissue"} xref: WBbt:0005779 xref: Wikipedia:Striated_muscle is_a: UBERON:0002385 ! muscle tissue intersection_of: UBERON:0002385 ! muscle tissue intersection_of: RO:0002473 CL:0000737 ! composed primarily of striated muscle cell relationship: RO:0002473 CL:0000737 ! composed primarily of striated muscle cell [Term] id: UBERON:0002040 name: bronchial artery namespace: uberon def: "A systemic artery that supplies the lung with with oxygenated blood." [UBERON:cjm, Wikipedia:Bronchial_artery] synonym: "bronchial arterial tree" EXACT [] xref: EMAPA:18608 xref: FMA:68109 xref: GAID:477 xref: MA:0001923 xref: MESH:D001981 xref: NCIT:C32230 xref: SCTID:244247009 xref: UMLS:C0006257 {source="ncithesaurus:Bronchial_Artery"} xref: Wikipedia:Bronchial_artery is_a: UBERON:0004573 ! systemic artery intersection_of: UBERON:0004573 ! systemic artery intersection_of: BFO:0000050 UBERON:0004571 ! part of systemic arterial system intersection_of: RO:0002178 UBERON:0002048 ! supplies lung relationship: BFO:0000050 RO:0002577 ! part of system relationship: BFO:0000051 UBERON:0004848 ! has part respiratory system arterial endothelium relationship: BFO:0000051 UBERON:0012416 ! has part respiratory system arterial smooth muscle relationship: RO:0002178 UBERON:0002048 ! supplies lung property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/a/a7/Gray1032.png" xsd:anyURI [Term] id: UBERON:0002047 name: pontine raphe nucleus namespace: uberon def: "The pontine raphe nucleus is one of the raphe nuclei. It is located in the pontine tegmentum. [WP,unvetted]." [Wikipedia:Pontine_raphe_nucleus] synonym: "raphe of pons" EXACT [] xref: BAMS:PnR xref: BAMS:RA-PONS xref: BAMS:RPn xref: BIRNLEX:1110 xref: DHBA:12471 xref: DHBA:12475 xref: FMA:68875 xref: HBA:9159 xref: MA:0001022 xref: MBA:238 xref: neuronames:589 {source="BIRNLEX:1110"} xref: UMLS:C0175423 {source="BIRNLEX:1110"} xref: Wikipedia:Pontine_raphe_nucleus is_a: UBERON:0006331 ! brainstem nucleus is_a: UBERON:0009662 ! hindbrain nucleus relationship: BFO:0000050 UBERON:0003023 ! part of pontine tegmentum relationship: BFO:0000050 UBERON:0004684 {source="Wikipedia"} ! part of raphe nuclei [Term] id: UBERON:0002048 name: lung namespace: uberon def: "Respiration organ that develops as an outpocketing of the esophagus." [http://orcid.org/0000-0002-6601-2165] xref: AAO:0000275 xref: AAO:0010567 xref: BTO:0000763 xref: CALOHA:TS-0568 xref: EFO:0000934 xref: EHDAA2:0001042 xref: EHDAA:1554 xref: EHDAA:2205 xref: EMAPA:16728 xref: EV:0100042 xref: FMA:7195 xref: GAID:345 xref: galen:Lung xref: MA:0000415 xref: MAT:0000135 xref: MESH:D008168 xref: MIAA:0000135 xref: NCIT:C12468 xref: SCTID:181216001 xref: UMLS:C0024109 {source="ncithesaurus:Lung"} xref: VHOG:0000310 xref: Wikipedia:Lung xref: XAO:0000119 is_a: UBERON:0000171 ! respiration organ is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0005178 ! thoracic cavity element is_a: UBERON:0015212 ! lateral structure relationship: BSPO:0000126 UBERON:0000170 ! in lateral side of pair of lungs relationship: RO:0002160 NCBITaxon:7776 ! only in taxon Gnathostomata relationship: RO:0002202 UBERON:0000118 ! develops from lung bud relationship: RO:0002219 UBERON:0009778 {gci_filler="NCBITaxon:9606", gci_relation="BFO:0000050", source="FMA"} ! surrounded by pleural sac relationship: RO:0002433 UBERON:0001004 ! contributes to morphology of respiratory system property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.4/3d-vh-f-lung.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.4/3d-vh-m-lung.glb" xsd:anyURI [Term] id: UBERON:0002049 name: vasculature namespace: uberon def: "An interconnected tubular multi-tissue structure contains fluid that is actively transported around the organism[ZFA]. Examples: vasculature of lung, vasculature of face." [ZFA:0005249] synonym: "vascular network" EXACT [FMA:69050] xref: BTO:0003718 xref: FMA:69050 xref: TAO:0005249 xref: ZFA:0005249 is_a: UBERON:0000477 {source="FMA"} ! anatomical cluster relationship: BFO:0000050 UBERON:0007798 ! part of vascular system relationship: BFO:0000051 UBERON:0000179 ! has part haemolymphatic fluid relationship: RO:0002473 UBERON:0000055 ! composed primarily of vessel property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/2/29/Circulatory_System_en.svg" xsd:anyURI [Term] id: UBERON:0002050 name: embryonic structure namespace: uberon def: "Anatomical structure that is part of an embryo." [BTO:0000174, ZFIN:curator] synonym: "developing embryonic structure" EXACT [FBbt:00004208] synonym: "embryonic anatomical structure" EXACT [RETIRED_EHDAA2:0003169] xref: AAO:0000138 xref: BILA:0000034 xref: BTO:0000174 xref: CALOHA:TS-2110 xref: EFO:0000461 xref: FMA:69067 xref: GAID:407 xref: MESH:D004628 xref: NCIT:C13229 xref: RETIRED_EHDAA2:0003169 xref: SCTID:667009 xref: TAO:0001105 xref: UMLS:C0013948 {source="ncithesaurus:Embryonic_Structure"} xref: VSAO:0000178 xref: XAO:0003042 xref: ZFA:0001105 is_a: UBERON:0005423 ! developing anatomical structure intersection_of: UBERON:0005423 ! developing anatomical structure intersection_of: BFO:0000050 UBERON:0000922 ! part of embryo relationship: BFO:0000050 UBERON:0000922 ! part of embryo [Term] id: UBERON:0002057 name: phrenic artery namespace: uberon def: "An artery that supplies the diaphragm." [https://orcid.org/0000-0002-6601-2165] xref: EMAPA:37108 {source="MA:th"} xref: FMA:69330 xref: MA:0002019 xref: NCIT:C33320 xref: UMLS:C1181536 {source="ncithesaurus:Phrenic_Artery"} is_a: UBERON:0004573 ! systemic artery intersection_of: UBERON:0004573 ! systemic artery intersection_of: RO:0002178 UBERON:0001103 ! supplies diaphragm relationship: BFO:0000050 RO:0002577 ! part of system relationship: RO:0002178 UBERON:0001103 ! supplies diaphragm [Term] id: UBERON:0002061 name: truncus arteriosus namespace: uberon def: "The truncus arteriosus and bulbus cordis are divided by the aorticopulmonary septum. The truncus arteriosus gives rise to the ascending aorta and the pulmonary trunk. The bulbus cordis gives rise to the smooth parts (outflow tract) of the left and right ventricles." [Wikipedia:Truncus_arteriosus_(embryology)] xref: EHDAA2:0004143 xref: EMAPA:35887 xref: FMA:70301 xref: GAID:554 xref: MA:0000103 xref: MESH:D014338 xref: NCIT:C34317 xref: SCTID:308828009 xref: UMLS:C1519589 {source="ncithesaurus:Trancus_Arteriosus"} xref: Wikipedia:Truncus_arteriosus_(embryology) is_a: UBERON:0001637 {source="EHDAA2"} ! artery is_a: UBERON:0002050 {source="FMA"} ! embryonic structure is_a: UBERON:0003498 ! heart blood vessel relationship: BFO:0000050 UBERON:0004145 {source="MA"} ! part of outflow tract relationship: BFO:0000050 UBERON:0005498 {source="EHDAA2"} ! part of primitive heart tube relationship: RO:0002202 UBERON:0005432 {source="EHDAA2"} ! develops from aortic sac [Term] id: UBERON:0002062 name: endocardial cushion namespace: uberon def: "The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves[GO]. Swellings of tissue present between the endocardial and myocardial cell layers that will give rise to the interstitial cells of the cardiac valves[ZFA]." [GO:0003197, Wikipedia:Atrioventricular_cushions, ZFIN:curator] synonym: "atrioventricular cushion" EXACT [Wikipedia:Endocardial_cushion] synonym: "AV cushion" EXACT [] synonym: "cardiac cushion" EXACT [PMID:15797462] synonym: "endocardial cushion tissue" EXACT [EHDAA2:0000434] xref: EHDAA2:0000434 xref: EHDAA2:0004028 xref: EHDAA:2586 xref: EMAPA:16696 xref: FMA:70302 xref: MA:0000078 xref: TAO:0001317 xref: VHOG:0000932 xref: Wikipedia:Atrioventricular_cushions xref: XAO:0004189 xref: ZFA:0001317 is_a: UBERON:0002050 ! embryonic structure is_a: UBERON:0005256 ! trunk mesenchyme is_a: UBERON:0009751 ! cardiac mesenchyme is_a: UBERON:0014387 ! mesenchyme derived from neural crest relationship: BFO:0000050 UBERON:0002165 {source="ZFA"} ! part of endocardium property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/c/c7/Gray465.png" xsd:anyURI [Term] id: UBERON:0002063 name: sinus venosus namespace: uberon def: "The sinus venosus is a large cardiac chamber at the inflow tract that receives venous blood from systemic circulation. precedes the atrium on the venous side of the chordate heart." [PMID:20735616, Wikipedia:Sinus_venosus] xref: AAO:0010505 xref: EHDAA2:0001839 xref: EHDAA:480 xref: EMAPA:16237 xref: FMA:70303 xref: NCIT:C34299 xref: NCIT:C34300 xref: TAO:0000154 xref: UMLS:C0225857 {source="ncithesaurus:Sinus_Venarum"} xref: UMLS:C0231084 {source="ncithesaurus:Sinus_Venosus"} xref: VHOG:0000177 xref: Wikipedia:Sinus_venosus xref: ZFA:0000154 is_a: UBERON:0004151 ! cardiac chamber relationship: BFO:0000050 UBERON:0002350 {source="VHOG"} ! part of conducting system of heart relationship: RO:0002495 UBERON:0007278 {source="Bgee:AN"} ! immediate transformation of presumptive sinus venosus property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/c/c7/Gray465.png" xsd:anyURI [Term] id: UBERON:0002067 name: dermis namespace: uberon def: "The dermis is a layer of skin between the epidermis (with which it makes up the skin) and subcutaneous tissues, and is composed of two layers, the papillary and reticular dermis[WP]." [Wikipedia:Dermis, ZFIN:curator] synonym: "vertebrate dermis" EXACT [] xref: AAO:0000128 xref: BTO:0000294 xref: CALOHA:TS-2076 xref: EFO:0000953 xref: EMAPA:17527 xref: EV:0100154 xref: FMA:70323 xref: GAID:1321 xref: MA:0000152 xref: MAT:0000153 xref: MESH:D020405 xref: MIAA:0000153 xref: NCIT:C12701 xref: SCTID:361696001 xref: TAO:0001119 xref: UMLS:C0011646 {source="ncithesaurus:Dermis"} xref: VHOG:0000108 xref: Wikipedia:Dermis xref: XAO:0000217 xref: ZFA:0001119 is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0010314 ! structure with developmental contribution from neural crest is_a: UBERON:0013754 ! integumentary system layer relationship: BFO:0000050 UBERON:0002097 {source="FMA"} ! part of skin of body relationship: BFO:0000051 GO:0071953 ! has part elastic fiber relationship: BFO:0000051 UBERON:0011860 ! has part collection of collagen fibrils relationship: BSPO:0000107 UBERON:0001003 ! deep to skin epidermis relationship: BSPO:0000108 UBERON:0002072 ! superficial to hypodermis relationship: RO:0002473 UBERON:0002384 ! composed primarily of connective tissue relationship: RO:0002495 UBERON:0010083 ! immediate transformation of future dermis property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/2/23/EpidermisPainted.svg" xsd:anyURI [Term] id: UBERON:0002072 name: hypodermis namespace: uberon def: "Lowermost layer of the integumentary system in vertebrates. Types of cells that are found in the hypodermis are fibroblasts, adipose cells, and macrophages. It is derived from the mesoderm, but unlike the dermis, it is not derived from the dermatome region of the mesoderm. The hypodermis is used mainly for fat storage[WP]." [Wikipedia:Hypodermis] synonym: "hypoderm" EXACT [] synonym: "vertebrate hypodermis" EXACT [] xref: BTO:0001314 xref: CALOHA:TS-2366 xref: EMAPA:37505 {source="MA:th"} xref: FMA:70544 xref: NCIT:C33645 xref: TAO:0001136 xref: UMLS:C0278403 {source="ncithesaurus:Subcutis"} xref: Wikipedia:Hypodermis xref: ZFA:0001136 is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0013754 ! integumentary system layer relationship: BFO:0000050 UBERON:0002199 {source="ZFA"} ! part of integument relationship: BSPO:0000107 UBERON:0002067 ! deep to dermis relationship: BSPO:0000108 UBERON:0001015 ! superficial to musculature relationship: RO:0002473 UBERON:0001013 ! composed primarily of adipose tissue relationship: RO:0002473 UBERON:0011825 {source="FMA-modified"} ! composed primarily of loose connective tissue property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/6/6d/Skin.svg" xsd:anyURI [Term] id: UBERON:0002075 name: viscus namespace: uberon def: "An organ that is located within the body cavity (or in its extension, in the scrotum); it consists of organ parts that are embryologically derived from endoderm, splanchnic mesoderm or intermediate mesoderm; together with other organs, the viscus constitutes the respiratory, gastrointestinal, urinary, reproductive and immune systems, or is the central organ of the cardiovascular system. Examples: heart, lung, esophagus, kidney, ovary, spleen." [BTO:0001491, https://github.com/obophenotype/mouse-anatomy-ontology/issues/14, Wikipedia:Viscus] synonym: "visceral organ" EXACT [RETIRED_EHDAA2:0002201] synonym: "visceral organ system" EXACT [MA:0000019] xref: AAO:0010386 xref: BTO:0001491 xref: EHDAA:512 xref: EMAPA:16245 xref: FMA:7085 xref: MA:0000019 xref: MESH:D014781 xref: NCIT:C28287 xref: RETIRED_EHDAA2:0002201 xref: SCTID:118760003 xref: UMLS:C0042779 {source="ncithesaurus:Viscera"} xref: Wikipedia:Viscus xref: XAO:0003034 is_a: UBERON:0005177 ! trunk region element intersection_of: UBERON:0000062 ! organ intersection_of: RO:0001025 UBERON:0002323 ! located in coelemic cavity lumen relationship: RO:0001025 UBERON:0002323 ! located in coelemic cavity lumen [Term] id: UBERON:0002078 name: right cardiac atrium namespace: uberon def: "A cardiac atrium that is in the right side of the heart. It receives deoxygenated blood. In mammals, this comes from the superior and inferior vena cava and the coronary sinus, and pumps it into the right ventricle through the tricuspid valve." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Right_atrium] synonym: "cardiac right atrium" EXACT [] synonym: "heart right atrium" EXACT [MA:0000075] synonym: "right atrium" EXACT [VHOG:0000328] synonym: "right atrium of heart" EXACT [] synonym: "right cardiac atrium" EXACT [] xref: AAO:0010248 xref: BTO:0001703 xref: EHDAA2:0000290 xref: EMAPA:17321 xref: FMA:7096 xref: galen:RightAtrium xref: MA:0000075 xref: NCIT:C12868 xref: SCTID:244383003 xref: UMLS:C0225844 {source="ncithesaurus:Right_Atrium"} xref: VHOG:0000328 xref: Wikipedia:Right_atrium xref: XAO:0003192 is_a: UBERON:0002081 ! cardiac atrium is_a: UBERON:0035554 ! right cardiac chamber intersection_of: UBERON:0002081 ! cardiac atrium intersection_of: BSPO:0000121 UBERON:0000948 ! in right side of heart relationship: BFO:0000050 RO:0002577 ! part of system relationship: RO:0002170 UBERON:0004537 ! connected to blood vasculature property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/2/20/Diagram_of_the_human_heart_%28cropped%29.svg" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Heart.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Heart.glb" xsd:anyURI [Term] id: UBERON:0002079 name: left cardiac atrium namespace: uberon def: "A cardiac atrium that is in the left side of the heart. It receives oxygenated blood from the pulmonary veins, In mammals this is pumped into the left ventricle, via the Mitral valve." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Left_atrium] synonym: "cardiac left atrium" EXACT [] synonym: "heart left atrium" EXACT [MA:0000074] synonym: "left atrium" EXACT [VHOG:0000369] synonym: "left atrium of heart" EXACT [] synonym: "left cardiac atrium" EXACT [] xref: AAO:0010247 xref: BTO:0001702 xref: EHDAA2:0000275 xref: EMAPA:17315 xref: FMA:7097 xref: galen:LeftAtrium xref: MA:0000074 xref: NCIT:C12869 xref: SCTID:244387002 xref: UMLS:C0225860 {source="ncithesaurus:Left_Atrium"} xref: VHOG:0000369 xref: Wikipedia:Left_atrium xref: XAO:0003191 is_a: UBERON:0002081 ! cardiac atrium is_a: UBERON:0035553 ! left cardiac chamber intersection_of: UBERON:0002081 ! cardiac atrium intersection_of: BSPO:0000120 UBERON:0000948 ! in left side of heart relationship: BFO:0000050 RO:0002577 ! part of system relationship: RO:0002170 UBERON:0004537 ! connected to blood vasculature property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/2/20/Diagram_of_the_human_heart_%28cropped%29.svg" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Heart.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Heart.glb" xsd:anyURI [Term] id: UBERON:0002080 name: heart right ventricle namespace: uberon def: "A cardiac ventricle that is in the right side of the heart." [http://orcid.org/0000-0002-6601-2165] synonym: "cardiac right ventricle" EXACT [] synonym: "right ventricle" EXACT [FMA:7098] synonym: "right ventricle of heart" EXACT [] xref: BTO:0001630 xref: CALOHA:TS-0443 xref: EHDAA2:0000196 xref: EMAPA:17340 xref: FMA:7098 xref: galen:RightVentricle xref: MA:0000093 xref: NCIT:C12870 xref: SCTID:244384009 xref: UMLS:C0225883 {source="ncithesaurus:Right_Ventricle"} xref: VHOG:0000717 xref: Wikipedia:Right_ventricle is_a: UBERON:0002082 ! cardiac ventricle is_a: UBERON:0035554 ! right cardiac chamber intersection_of: UBERON:0002082 ! cardiac ventricle intersection_of: BSPO:0000121 UBERON:0000948 ! in right side of heart relationship: BFO:0000050 RO:0002577 ! part of system relationship: RO:0002170 UBERON:0004537 ! connected to blood vasculature relationship: RO:0002202 UBERON:0009889 {source="PMID:17276708"} ! develops from secondary heart field relationship: RO:0002254 UBERON:0004706 {source="cjm"} ! has developmental contribution from bulbus cordis property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/2/20/Diagram_of_the_human_heart_%28cropped%29.svg" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Heart.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Heart.glb" xsd:anyURI [Term] id: UBERON:0002081 name: cardiac atrium namespace: uberon def: "Cardiac chamber in which blood enters the heart." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Heart_atrium] synonym: "atrium" EXACT [ZFA:0000471] synonym: "atrium of heart" EXACT [] synonym: "heart atrium" EXACT [] xref: AAO:0010246 xref: BTO:0000903 xref: CALOHA:TS-0437 xref: EFO:0000277 xref: EHDAA2:0000154 xref: EHDAA:1265 xref: EMAPA:16688 xref: EV:0100019 xref: FMA:7099 xref: GAID:555 xref: galen:Atrium xref: MA:0000073 xref: MAT:0000496 xref: MESH:D006325 xref: NCIT:C12728 xref: SCTID:261405004 xref: TAO:0000471 xref: UMLS:C0018792 {source="ncithesaurus:Cardiac_Atrium"} xref: VHOG:0000175 xref: Wikipedia:Heart_atrium xref: ZFA:0000471 is_a: UBERON:0004151 ! cardiac chamber relationship: RO:0002433 UBERON:0000948 ! contributes to morphology of heart relationship: RO:0002495 UBERON:0010227 ! immediate transformation of future cardiac atrium [Term] id: UBERON:0002082 name: cardiac ventricle namespace: uberon def: "Cardiac chamber through which blood leaves the heart." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Ventricle_(heart)] synonym: "heart ventricle" EXACT [] synonym: "lower chamber of heart" EXACT [] synonym: "ventricle of heart" EXACT [] xref: AAO:0010249 xref: BTO:0000862 xref: CALOHA:TS-0444 xref: EFO:0000317 xref: EHDAA2:0004164 xref: EHDAA:1912 xref: EMAPA:17331 xref: EV:0100020 xref: FMA:7100 xref: GAID:568 xref: galen:Ventricle xref: MA:0000091 xref: MAT:0000497 xref: MESH:D006352 xref: NCIT:C12730 xref: SCTID:277699000 xref: TAO:0000009 xref: UMLS:C0018827 {source="ncithesaurus:Cardiac_Ventricle"} xref: VHOG:0000435 xref: Wikipedia:Ventricle_(heart) xref: XAO:0003193 xref: ZFA:0000009 is_a: UBERON:0004151 ! cardiac chamber relationship: RO:0002433 UBERON:0000948 ! contributes to morphology of heart relationship: RO:0002495 UBERON:0006283 {source="Bgee:AN"} ! immediate transformation of future cardiac ventricle [Term] id: UBERON:0002084 name: heart left ventricle namespace: uberon def: "A cardiac ventricle that is in the left side of the heart." [http://orcid.org/0000-0002-6601-2165] synonym: "cardiac left ventricle" EXACT [] synonym: "left cardiac ventricle" EXACT [] synonym: "left ventricle" EXACT [FMA:7101] synonym: "left ventricle of heart" EXACT [] xref: BTO:0001629 xref: CALOHA:TS-0439 xref: EHDAA2:0002178 xref: EMAPA:17337 xref: FMA:7101 xref: galen:LeftVentricle xref: MA:0000092 xref: NCIT:C12871 xref: SCTID:244385005 xref: UMLS:C0225897 {source="ncithesaurus:Left_Ventricle"} xref: VHOG:0000718 xref: Wikipedia:Left_ventricle is_a: UBERON:0002082 ! cardiac ventricle is_a: UBERON:0035553 ! left cardiac chamber intersection_of: UBERON:0002082 ! cardiac ventricle intersection_of: BSPO:0000120 UBERON:0000948 ! in left side of heart relationship: BFO:0000050 RO:0002577 ! part of system relationship: RO:0002150 UBERON:0000947 ! continuous with aorta relationship: RO:0002170 UBERON:0004537 ! connected to blood vasculature property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/2/20/Diagram_of_the_human_heart_%28cropped%29.svg" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Heart.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Heart.glb" xsd:anyURI [Term] id: UBERON:0002085 name: interatrial septum namespace: uberon def: "A cardiac septum that divides the left and right atria of the heart." [http://orcid.org/0000-0002-6601-2165] synonym: "atrial septum" EXACT [] synonym: "atrium septum" EXACT [] synonym: "interatrial septal wall" EXACT [] xref: EHDAA2:0000838 xref: EHDAA:1896 xref: EMAPA:17011 xref: FMA:7108 xref: galen:InteratrialSeptum xref: MA:0000084 xref: NCIT:C32818 xref: SCTID:362016003 xref: UMLS:C0225836 {source="ncithesaurus:Interatrial_Septum"} xref: VHOG:0000385 xref: Wikipedia:Interatrial_septum is_a: UBERON:0002099 ! cardiac septum intersection_of: UBERON:0002099 ! cardiac septum intersection_of: RO:0002220 UBERON:0002078 ! adjacent to right cardiac atrium intersection_of: RO:0002220 UBERON:0002079 ! adjacent to left cardiac atrium relationship: RO:0002220 UBERON:0002078 ! adjacent to right cardiac atrium relationship: RO:0002220 UBERON:0002079 ! adjacent to left cardiac atrium property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/6/6c/Gray493.png" xsd:anyURI [Term] id: UBERON:0002090 name: postcranial axial skeleton namespace: uberon def: "The postcranial subdivision of skeleton structural components forming the long axis of the vertebrate body; in Danio, consisting of the notochord, vertebrae, ribs, supraneurals, intermuscular bones, and unpaired median fins; in human consists of the bones of the vertebral column, the thoracic cage and the pelvis[ZFA+FMA]." [https://sourceforge.net/tracker/?func=detail&aid=2983975&group_id=76834&atid=974957, https://sourceforge.net/tracker/?func=detail&atid=1205376&aid=2983977&group_id=76834, ZFA:0000317] synonym: "post-cranial axial skeleton" EXACT [] xref: AAO:0000034 xref: EFO:0000942 xref: EHDAA2:0000161 xref: EHDAA:5049 xref: EMAPA:17214 xref: EMAPA:37721 {source="MA:th"} xref: FMA:71221 xref: MA:0002986 xref: MAT:0000148 xref: MIAA:0000148 xref: TAO:0000317 xref: VHOG:0000317 xref: VSAO:0000093 xref: XAO:0003073 xref: ZFA:0000317 is_a: UBERON:0010912 ! subdivision of skeleton relationship: BFO:0000050 UBERON:0005944 ! part of axial skeleton plus cranial skeleton relationship: BFO:0000050 UBERON:0011138 ! part of postcranial axial skeletal system relationship: RO:0002202 UBERON:0003089 ! develops from sclerotome [Term] id: UBERON:0002091 name: appendicular skeleton namespace: uberon def: "Subdivision of skeleton which which consists of all the skeletal elements in in the pectoral and pelvic appendage complexes[cjm]." [https://orcid.org/0000-0002-6601-2165, UBERONREF:0000003, Wikipedia:Appendicular_skeleton] synonym: "appendicular skeleton" EXACT [] synonym: "entire appendicular skeleton" EXACT [https://github.com/obophenotype/uberon/issues/59] xref: AAO:0000747 xref: EFO:0000951 xref: EMAPA:32729 xref: FMA:71222 xref: MA:0000290 xref: MAT:0000278 xref: MIAA:0000278 xref: NCIT:C49477 xref: SCTID:322050006 xref: UMLS:C0222646 {source="ncithesaurus:Appendicular_Skeleton"} xref: VHOG:0001666 xref: VSAO:0000076 xref: Wikipedia:Appendicular_skeleton xref: XAO:0003166 is_a: UBERON:0010912 ! subdivision of skeleton relationship: BFO:0000050 UBERON:0011249 ! part of appendicular skeletal system relationship: RO:0002131 UBERON:0000026 ! overlaps appendage relationship: RO:0002160 NCBITaxon:7776 ! only in taxon Gnathostomata relationship: RO:0002433 UBERON:0001434 ! contributes to morphology of skeletal system property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/7/7c/Appendicular_skeleton_diagram.svg" xsd:anyURI [Term] id: UBERON:0002094 name: interventricular septum namespace: uberon def: "Cardiac septum which separates the right ventricle from the left ventricle.[FMA]." [FMA:7133] synonym: "heart interventricular septum" EXACT [MA:0000085] synonym: "heart ventricular septum" EXACT [MA:0000085] xref: BTO:0002483 xref: EFO:0001956 xref: EHDAA:2603 xref: EMAPA:17333 xref: FMA:7133 xref: galen:InterventricularSeptum xref: MA:0000085 xref: NCIT:C32874 xref: SCTID:362019005 xref: UMLS:C0225870 {source="ncithesaurus:Interventricular_Septum"} xref: VHOG:0000386 xref: Wikipedia:Interventricular_septum is_a: UBERON:0002099 ! cardiac septum intersection_of: UBERON:0002099 ! cardiac septum intersection_of: RO:0002220 UBERON:0002080 ! adjacent to heart right ventricle intersection_of: RO:0002220 UBERON:0002084 ! adjacent to heart left ventricle relationship: RO:0002220 UBERON:0002080 ! adjacent to heart right ventricle relationship: RO:0002220 UBERON:0002084 ! adjacent to heart left ventricle property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/9/96/Gray498.png" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Heart.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Heart.glb" xsd:anyURI [Term] id: UBERON:0002095 name: mesentery namespace: uberon def: "Anatomical organ component composed of a double layer of serous membrane that suspends a viscus from the body wall or connects adjacent viscera and in doing so conveys blood vessels, lymphatics and nerves to and from the viscera. Examples: greater omentum, broad ligament of uterus, sigmoid mesocolon." [FMA:7144, https://github.com/obophenotype/uberon/issues/85, Wikipedia:Mesentery, Wikipedia:Mesentery#Mesentery_.28general.29] synonym: "generic mesentery" EXACT [Wikipedia:Mesentery] synonym: "mesentery (generic)" EXACT [Wikipedia:Mesentery] xref: AAO:0011061 xref: BTO:0001380 xref: EV:0100083 xref: FMA:7144 xref: GAID:21 xref: galen:Mesentery xref: MESH:D008643 xref: NCIT:C33103 xref: SCTID:362707009 xref: UMLS:C0025474 {source="ncithesaurus:Mesentery"} xref: Wikipedia:Mesentery#Mesentery_.28general.29 is_a: UBERON:0000042 ! serous membrane relationship: RO:0002160 NCBITaxon:6072 ! only in taxon Eumetazoa property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/1/19/Gray1038.png" xsd:anyURI property_value: x_1.1:contributor https://github.com/cmungall [Term] id: UBERON:0002097 name: skin of body namespace: uberon def: "The organ covering the body that consists of the dermis and epidermis." [UBERON:cjm] synonym: "entire skin" EXACT [] synonym: "skin organ" EXACT [] xref: BTO:0001253 xref: CALOHA:TS-0934 xref: EFO:0000962 xref: EHDAA2:0001844 xref: EMAPA:17525 xref: FMA:7163 xref: galen:Skin xref: MESH:D012867 xref: MFMO:0000099 xref: NCIT:C12470 xref: SCTID:181469002 xref: UMLS:C1123023 {source="ncithesaurus:Skin"} xref: Wikipedia:Skin xref: XAO:0000023 is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000062 ! organ is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0010314 ! structure with developmental contribution from neural crest relationship: BFO:0000050 UBERON:0002199 ! part of integument relationship: RO:0002202 UBERON:0011272 {source="Wikipathways:WP2062"} ! develops from embryonic skin basal layer relationship: RO:0002473 UBERON:0000014 ! composed primarily of zone of skin property_value: IAO:0000232 "consider 'integumentary system' for invertebrates" xsd:string property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/6/6d/Skin.svg" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.0/VH_F_Skin.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.0/VH_M_Skin.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Skin.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.3/3d-vh-f-skin.glb" xsd:anyURI [Term] id: UBERON:0002099 name: cardiac septum namespace: uberon def: "The thin membranous structure between the two heart atria or the thick muscular structure between the two heart ventricles." [MESH:A07.541.459] synonym: "heart septum" EXACT [] synonym: "septum of heart" EXACT [] xref: EMAPA:35400 xref: FMA:7180 xref: GAID:562 xref: MA:0000083 xref: MESH:D006346 xref: NCIT:C49485 xref: SCTID:362014000 xref: UMLS:C0018819 {source="ncithesaurus:Heart_Septum"} is_a: UBERON:0003037 ! septum is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0003037 ! septum intersection_of: BFO:0000050 UBERON:0000948 ! part of heart relationship: BFO:0000050 UBERON:0000948 ! part of heart relationship: RO:0002220 UBERON:0004151 ! adjacent to cardiac chamber relationship: RO:0002433 UBERON:0000948 ! contributes to morphology of heart [Term] id: UBERON:0002100 name: trunk namespace: uberon def: "Organism subdivision which is the part of the body posterior to the cervical region (or head, when cervical region not present) and anterior to the caudal region. Includes the sacrum when present." [TAO:0001115, UBERONREF:0000006, Wikipedia:Torso] synonym: "thoracolumbar region" EXACT [] synonym: "torso" EXACT [] synonym: "trunk region" EXACT [XAO:0000054] xref: AAO:0010339 xref: BILA:0000116 xref: BTO:0001493 xref: CALOHA:TS-1071 xref: EFO:0000966 xref: EMAPA:31857 xref: FMA:7181 xref: galen:Trunk xref: MA:0000004 xref: MAT:0000296 xref: MIAA:0000296 xref: NCIT:C33816 xref: SCTID:262225004 xref: TAO:0001115 xref: UMLS:C0460005 {source="ncithesaurus:Trunk"} xref: Wikipedia:Torso xref: XAO:0000054 xref: XAO:0003025 xref: ZFA:0001115 is_a: UBERON:0011676 ! subdivision of organism along main body axis relationship: BFO:0000050 UBERON:0013702 ! part of body proper relationship: BFO:0000051 UBERON:0000915 {gci_filler="NCBITaxon:7742", gci_relation="BFO:0000050"} ! has part thoracic segment of trunk relationship: BFO:0000051 UBERON:0000916 {gci_filler="NCBITaxon:7742", gci_relation="BFO:0000050"} ! has part abdomen [Term] id: UBERON:0002104 name: visual system namespace: uberon def: "The sensory system subserving the sense of vision." [NIFSTD:FMAID_7191] synonym: "photosensory system" EXACT [BILA:0000140] synonym: "visual organ system" EXACT [] xref: AAO:0000632 xref: BILA:0000140 xref: EMAPA:36003 xref: FMA:7191 xref: http://uri.neuinfo.org/nif/nifstd/FMAID_7191 xref: MA:0002444 xref: NCIT:C12888 xref: SCTID:281831001 xref: TAO:0001127 xref: UMLS:C0587900 {source="ncithesaurus:Visual_System"} xref: Wikipedia:Visual_system xref: XAO:0003198 xref: ZFA:0001127 is_a: UBERON:0001032 ! sensory system relationship: RO:0002216 GO:0007601 ! capable of part of visual perception [Term] id: UBERON:0002105 name: vestibulo-auditory system namespace: uberon def: "Sensory system responsible for the perception of spatial orientation and auditory stimuli." [ZFA:0001138] synonym: "auditory organ system" EXACT [] synonym: "vestibuloauditory system" EXACT [] xref: AAO:0000631 xref: EMAPA:36002 xref: EMAPA:37985 {source="MA:th"} xref: FMA:78500 xref: TAO:0001138 xref: XAO:0003195 xref: ZFA:0001138 is_a: UBERON:0001032 ! sensory system relationship: RO:0002216 GO:0007605 ! capable of part of sensory perception of sound property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/d/d2/Anatomy_of_the_Human_Ear.svg" xsd:anyURI [Term] id: UBERON:0002106 name: spleen namespace: uberon def: "The organ that functions to filter blood and to store red corpuscles and platelets." [ISBN:0-683-40008-8, MP:0000689] xref: AAO:0010395 xref: BTO:0001281 xref: CALOHA:TS-0956 xref: EFO:0000869 xref: EMAPA:18767 xref: EV:0100055 xref: FMA:7196 xref: GAID:1289 xref: galen:Spleen xref: MA:0000141 xref: MAT:0000085 xref: MESH:D013154 xref: MIAA:0000085 xref: NCIT:C12432 xref: SCTID:181279003 xref: TAO:0000436 xref: UMLS:C0037993 {source="ncithesaurus:Spleen"} xref: VHOG:0000120 xref: Wikipedia:Spleen xref: XAO:0000328 xref: ZFA:0000436 is_a: UBERON:0004177 ! hemopoietic organ is_a: UBERON:0005057 ! immune organ is_a: UBERON:0017672 ! abdominal viscera relationship: RO:0002160 NCBITaxon:7776 {source="multiple sources - true spleen appear in jawed vertebrates"} ! only in taxon Gnathostomata relationship: RO:0002202 UBERON:0006293 ! develops from spleen primordium property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.0/VH_F_Spleen.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Spleen.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Spleen.glb" xsd:anyURI property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/d/d6/Illu_spleen.jpg" xsd:anyURI [Term] id: UBERON:0002107 name: liver namespace: uberon def: "An exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes[GO]." [BTO:0000759, Wikipedia:Liver] xref: AAO:0010111 xref: BTO:0000759 xref: CALOHA:TS-0564 xref: EFO:0000887 xref: EHDAA2:0000997 xref: EHDAA:2197 xref: EMAPA:16846 xref: EV:0100089 xref: FMA:7197 xref: GAID:288 xref: galen:Liver xref: MA:0000358 xref: MAT:0000097 xref: MESH:D008099 xref: MIAA:0000097 xref: NCIT:C12392 xref: SCTID:181268008 xref: TAO:0000123 xref: UMLS:C0023884 {source="ncithesaurus:Liver"} xref: VHOG:0000257 xref: Wikipedia:Liver xref: XAO:0000133 xref: ZFA:0000123 is_a: UBERON:0002365 {source="BTO", source="EHDAA2", source="GO-def"} ! exocrine gland is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0005172 ! abdomen element is_a: UBERON:0006925 ! digestive system gland relationship: BFO:0000050 UBERON:0002423 {source="ZFA"} ! part of hepatobiliary system relationship: BFO:0000051 UBERON:0004647 ! has part liver lobule relationship: RO:0002131 UBERON:0002405 {source="ZFA-weakened"} ! overlaps immune system relationship: RO:0002160 NCBITaxon:7742 ! only in taxon Vertebrata relationship: RO:0002202 UBERON:0004161 {source="EHDAA2"} ! develops from septum transversum relationship: RO:0002202 UBERON:0008836 {source="http://www.stembook.org/node/512"} ! develops from liver bud relationship: RO:0002433 UBERON:0002423 ! contributes to morphology of hepatobiliary system relationship: RO:0003000 UBERON:0001970 ! produces bile relationship: site_of GO:0002384 ! hepatic immune response relationship: site_of GO:0005978 ! glycogen biosynthetic process relationship: site_of GO:0005980 ! glycogen catabolic process property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Liver.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Liver.glb" xsd:anyURI property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/6/64/Leber_Schaf.jpg" xsd:anyURI [Term] id: UBERON:0002108 name: small intestine namespace: uberon def: "Subdivision of digestive tract that connects the stomach to the large intestine and is where much of the digestion and absorption of food takes place (with the exception of ruminants). The mammalian small intestine is long and coiled and can be differentiated histologically into: duodenum, jejunem, ileum[WP,cjm,Kardong]." [ISBN:0073040584, Wikipedia:Small_intestine] synonym: "small bowel" EXACT [] synonym: "small intestine" EXACT [] xref: AAO:0010397 xref: BTO:0000651 xref: CALOHA:TS-0942 xref: EFO:0000841 xref: EMAPA:32834 xref: EV:0100072 xref: FMA:7200 xref: GAID:313 xref: galen:SmallIntestine xref: MA:0000337 xref: MAT:0000047 xref: MESH:D007421 xref: MIAA:0000047 xref: NCIT:C12386 xref: SCTID:181250005 xref: TAO:0001323 xref: UMLS:C0021852 {source="ncithesaurus:Small_Intestine"} xref: VHOG:0000055 xref: Wikipedia:Small_intestine xref: XAO:0000130 xref: ZFA:0001323 is_a: UBERON:0004921 ! subdivision of digestive tract is_a: UBERON:0013765 ! digestive system element relationship: BFO:0000050 UBERON:0000160 ! part of intestine relationship: RO:0002160 NCBITaxon:7742 ! only in taxon Vertebrata relationship: RO:0002433 UBERON:0000160 ! contributes to morphology of intestine property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/8/82/Stomach_colon_rectum_diagram.svg" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Small_Intestine.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Small_Intestine.glb" xsd:anyURI [Term] id: UBERON:0002110 name: gallbladder namespace: uberon def: "An organ that aids digestion and stores bile produced by the liver[WP]." [Wikipedia:Gallbladder] synonym: "cholecyst" EXACT [WikipediaVersioned:Gallbladder&oldid=1092217922] synonym: "gall bladder" EXACT [] xref: AAO:0010114 xref: BTO:0000493 xref: CALOHA:TS-0394 xref: EFO:0000853 xref: EHDAA2:0000699 xref: EHDAA:8062 xref: EMAPA:17202 xref: EV:0100090 xref: FMA:7202 xref: galen:Gallbladder xref: MA:0000356 xref: MAT:0000072 xref: MESH:D005704 xref: MIAA:0000072 xref: NCIT:C12377 xref: SCTID:181269000 xref: TAO:0000208 xref: UMLS:C0016976 {source="ncithesaurus:Gallbladder"} xref: VHOG:0000221 xref: Wikipedia:Gallbladder xref: XAO:0000135 xref: ZFA:0000208 is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0013765 ! digestive system element is_a: UBERON:0017672 ! abdominal viscera is_a: UBERON:0018707 {source="BTO"} ! bladder organ relationship: BFO:0000050 UBERON:0002294 ! part of biliary system relationship: RO:0002202 UBERON:0004912 ! develops from biliary bud relationship: RO:0002202 UBERON:0006242 ! develops from gallbladder primordium relationship: RO:0002433 UBERON:0001173 ! contributes to morphology of biliary tree property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/b/b1/GallbladderAnatomy-en.svg" xsd:anyURI property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/f/f4/Abdomal_organs.svg" xsd:anyURI [Term] id: UBERON:0002111 name: artery smooth muscle tissue namespace: uberon def: "A portion of smooth muscle tissue that is part of an artery [Automatically generated definition]." [OBOL:automatic] synonym: "arterial smooth muscle" EXACT [BTO:0000087] synonym: "artery smooth muscle" EXACT [] synonym: "artery smooth muscle tissue" EXACT [] synonym: "smooth muscle of artery" EXACT [FMA:72024] xref: BTO:0000087 xref: CALOHA:TS-1198 xref: EMAPA:36285 xref: FMA:72024 xref: MA:0000708 xref: NCIT:C49195 xref: UMLS:C1706851 {source="ncithesaurus:Artery_Smooth_Muscle_Tissue"} is_a: UBERON:0004237 ! blood vessel smooth muscle is_a: UBERON:0004695 ! arterial system smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: BFO:0000050 UBERON:0001637 ! part of artery relationship: BFO:0000050 UBERON:0001637 ! part of artery [Term] id: UBERON:0002112 name: smooth muscle of esophagus namespace: uberon def: "A portion of smooth muscle tissue that is part of a esophagus [Automatically generated definition]." [OBOL:automatic] synonym: "esophageal smooth muscle" EXACT [] synonym: "esophagus involuntary muscle" EXACT [OBOL:automatic] synonym: "esophagus non-striated muscle" EXACT [OBOL:automatic] synonym: "esophagus smooth muscle" EXACT [] synonym: "esophagus smooth muscle tissue" EXACT [OBOL:automatic] synonym: "gullet involuntary muscle" EXACT [OBOL:automatic] synonym: "gullet non-striated muscle" EXACT [OBOL:automatic] synonym: "gullet smooth muscle" EXACT [OBOL:automatic] synonym: "gullet smooth muscle tissue" EXACT [OBOL:automatic] synonym: "involuntary muscle of esophagus" EXACT [OBOL:automatic] synonym: "involuntary muscle of gullet" EXACT [OBOL:automatic] synonym: "involuntary muscle of oesophagus" EXACT [OBOL:automatic] synonym: "non-striated muscle of esophagus" EXACT [OBOL:automatic] synonym: "non-striated muscle of gullet" EXACT [OBOL:automatic] synonym: "non-striated muscle of oesophagus" EXACT [OBOL:automatic] synonym: "oesophagus involuntary muscle" EXACT [OBOL:automatic] synonym: "oesophagus non-striated muscle" EXACT [OBOL:automatic] synonym: "oesophagus smooth muscle tissue" EXACT [OBOL:automatic] synonym: "smooth muscle of gullet" EXACT [OBOL:automatic] synonym: "smooth muscle of oesophagus" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of esophagus" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of gullet" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of oesophagus" EXACT [OBOL:automatic] xref: EMAPA:35323 xref: FMA:72025 xref: MA:0001573 is_a: UBERON:0001135 ! smooth muscle tissue intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: BFO:0000050 UBERON:0001043 ! part of esophagus relationship: BFO:0000050 UBERON:0003832 ! part of esophagus muscle relationship: RO:0002433 UBERON:0001043 ! contributes to morphology of esophagus [Term] id: UBERON:0002113 name: kidney namespace: uberon def: "A paired organ of the urinary tract that produces urine and maintains bodily fluid homeostasis, blood pressure, pH levels, red blood cell production and skeleton mineralization." [http://anatomy.uams.edu/anatomyhtml/kidney.html, https://www.kidney.org/kidneydisease/top-5-jobs-kidneys-do, PMID:25140012, PMID:35003210, Wikipedia:Kidney] xref: AAO:0000250 xref: BTO:0000671 xref: CALOHA:TS-0510 xref: EFO:0000929 xref: EMAPA:17373 xref: EV:0100096 xref: FMA:7203 xref: GAID:423 xref: galen:Kidney xref: MA:0000368 xref: MAT:0000119 xref: MESH:D007668 xref: MIAA:0000119 xref: NCIT:C12415 xref: SCTID:181414000 xref: UMLS:C0022646 {source="ncithesaurus:Kidney"} xref: Wikipedia:Kidney xref: XAO:0003267 is_a: UBERON:0000489 ! cavitated compound organ is_a: UBERON:0005172 ! abdomen element is_a: UBERON:0015212 ! lateral structure relationship: BFO:0000050 UBERON:0011143 {source="FMA"} ! part of upper urinary tract relationship: BSPO:0000126 UBERON:0000468 ! in lateral side of multicellular organism relationship: RO:0002160 NCBITaxon:7742 ! only in taxon Vertebrata relationship: RO:0002202 UBERON:0003918 ! develops from kidney mesenchyme relationship: RO:0002202 UBERON:0005095 ! develops from kidney rudiment relationship: RO:0002433 UBERON:0001008 ! contributes to morphology of renal system [Term] id: UBERON:0002114 name: duodenum namespace: uberon def: "The first part of the small intestine. At the junction of the stomach and the duodenum the alimentary canal is inflected. The duodenum first goes anteriorly for a short distance, turns dorsally, and eventually caudally, thus it is a U-shaped structure with two horizontal sections (a ventral and a dorsal one)." [ISBN:0815318960, Wikipedia:Duodenum] xref: AAO:0010402 xref: BTO:0000365 xref: CALOHA:TS-0214 xref: EFO:0000851 xref: EMAPA:18852 xref: EV:0100073 xref: FMA:7206 xref: GAID:284 xref: galen:Duodenum xref: MA:0000338 xref: MAT:0000044 xref: MESH:D004386 xref: MIAA:0000044 xref: NCIT:C12263 xref: SCTID:181247007 xref: UMLS:C0013303 {source="ncithesaurus:Duodenum"} xref: VHOG:0000052 xref: Wikipedia:Duodenum xref: XAO:0000236 is_a: UBERON:0004921 ! subdivision of digestive tract relationship: BSPO:0001106 UBERON:0002108 ! proximalmost part of small intestine relationship: RO:0002150 UBERON:0001166 ! continuous with pylorus relationship: RO:0002433 UBERON:0002108 ! contributes to morphology of small intestine property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/b/b3/Tractus_intestinalis_duodenum.svg" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Small_Intestine.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Small_Intestine.glb" xsd:anyURI [Term] id: UBERON:0002118 name: right ovary namespace: uberon def: "An ovary that is part of a right side of organism [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:37367 {source="MA:th"} xref: FMA:7213 xref: MA:0001705 xref: NCIT:C33487 xref: SCTID:280123002 xref: UMLS:C0227873 {source="ncithesaurus:Right_Ovary"} is_a: UBERON:0000992 ! ovary is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0000992 ! ovary intersection_of: BSPO:0000121 UBERON:0000468 ! in right side of multicellular organism relationship: BSPO:0000121 UBERON:0000468 ! in right side of multicellular organism [Term] id: UBERON:0002119 name: left ovary namespace: uberon def: "An ovary that is part of a left side of organism [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:37366 {source="MA:th"} xref: FMA:7214 xref: MA:0001704 xref: NCIT:C32969 xref: SCTID:280124008 xref: UMLS:C0227874 {source="ncithesaurus:Left_Ovary"} is_a: UBERON:0000992 ! ovary is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0000992 ! ovary intersection_of: BSPO:0000120 UBERON:0000468 ! in left side of multicellular organism relationship: BSPO:0000120 UBERON:0000468 ! in left side of multicellular organism [Term] id: UBERON:0002120 name: pronephros namespace: uberon def: "In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensible for larval life[GO]." [GO:0048793, Wikipedia:Pronephros] synonym: "pronephric kidney" EXACT [XAO:0002000] xref: AAO:0011089 xref: BTO:0001541 xref: EFO:0000927 xref: EHDAA2:0001570 xref: EHDAA:1017 xref: EMAPA:16579 xref: FMA:72170 xref: MAT:0000117 xref: MIAA:0000117 xref: NCIT:C34280 xref: SCTID:308804007 xref: TAO:0000151 xref: UMLS:C0231048 {source="ncithesaurus:Pronephros"} xref: VHOG:0000037 xref: Wikipedia:Pronephros xref: XAO:0002000 xref: ZFA:0000151 is_a: UBERON:0002113 {source="GO"} ! kidney is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005423 ! developing anatomical structure relationship: RO:0001025 UBERON:0003887 {source="OG"} ! located in intraembryonic coelom relationship: RO:0002202 UBERON:0005721 {source="ZFA"} ! develops from pronephric mesoderm relationship: RO:0002202 UBERON:0005754 ! develops from rostral part of nephrogenic cord [Term] id: UBERON:0002128 name: superior olivary complex namespace: uberon def: "A collection of brainstem nuclei that functions in multiple aspects of hearing and is an important component of the ascending and descending auditory pathways of the auditory system." [ISBN:0-19-502694-2, Wikipedia:Superior_olivary_complex] synonym: "superior olivary nuclei" EXACT [FMA:72247] xref: BAMS:SOC xref: BIRNLEX:1307 xref: DHBA:12462 xref: EMAPA:35840 xref: EV:0100263 xref: FMA:72247 xref: HBA:9177 xref: MA:0001026 xref: MBA:398 xref: neuronames:569 {source="BIRNLEX:1307"} xref: UMLS:C0175427 {source="BIRNLEX:1307"} xref: VHOG:0001381 xref: Wikipedia:Superior_olivary_complex is_a: UBERON:0007245 ! nuclear complex of neuraxis is_a: UBERON:0019263 ! gray matter of hindbrain relationship: BFO:0000050 UBERON:0003023 {source="NIFSTD"} ! part of pontine tegmentum relationship: BFO:0000050 UBERON:0016490 ! part of auditory system property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/4/46/Gray713.png" xsd:anyURI [Term] id: UBERON:0002148 name: locus ceruleus namespace: uberon def: "The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic[GO]. Bluish region in the superior angle of the fourth ventricle floor, corresponding to melanin-like pigmented nerve cells which lie lateral to the ponto-mesencephalic central gray (griseum centrale). It is also known as nucleus pigmentosus pontis[GAID]." [GAID:577, GO:0021703, Wikipedia:Locus_ceruleus] synonym: "blue nucleus" EXACT [BIRNLEX:905] synonym: "caerulean nucleus" EXACT [] synonym: "locus caeruleus" EXACT [BIRNLEX:905] synonym: "locus coeruleu" EXACT [] synonym: "locus coeruleus" EXACT [] synonym: "Noradrenergic cell group A6" EXACT [Noradrenergic_cell_group_A6&oldid=981960774] synonym: "nucleus of locus caeruleus" EXACT [] synonym: "nucleus pigmentosus pontis" EXACT [BIRNLEX:905] synonym: "substantia ferruginea" EXACT [BIRNLEX:905] xref: BAMS:CAE xref: BAMS:LC xref: BIRNLEX:905 xref: BM:Pons-LC xref: BTO:0001408 xref: DHBA:12819 xref: DMBA:16972 xref: EFO:0001963 xref: EMAPA:35502 xref: FMA:72478 xref: GAID:577 xref: HBA:9148 xref: MA:0001017 xref: MBA:147 xref: MESH:D008125 xref: NCIT:C97333 xref: neuronames:583 {source="BIRNLEX:905"} xref: SCTID:369016004 xref: TAO:0000539 xref: UMLS:C0023951 {source="ncithesaurus:Locus_Coeruleus", source="BIRNLEX:905"} xref: Wikipedia:Locus_ceruleus xref: ZFA:0000539 is_a: UBERON:0006331 ! brainstem nucleus is_a: UBERON:0009662 ! hindbrain nucleus is_a: UBERON:8440015 ! noradrenergic cell groups relationship: BFO:0000050 UBERON:0003023 ! part of pontine tegmentum relationship: RO:0002215 GO:0048243 ! capable of norepinephrine secretion property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/7/77/Gray709.png" xsd:anyURI [Term] id: UBERON:0002149 name: superior salivatory nucleus namespace: uberon def: "Nucleus containing parasympathetic neurons giving rise to the parasympathetic division of the facial nerve, innervating the salivary glands (Brodal, Neurological Anatomy, 3rd ed., 1981, pg 703)." [BIRNLEX:1131] synonym: "superior salivary nucleus" EXACT [GO:0021753] xref: BAMS:SSN xref: BAMS:SuS xref: BIRNLEX:1131 xref: DHBA:12435 xref: EHDAA2:0004646 xref: EMAPA:37756 {source="MA:th"} xref: FMA:72482 xref: HBA:9194 xref: MA:0001027 xref: MBA:462 xref: neuronames:590 {source="BIRNLEX:1131"} xref: SCTID:369028007 xref: UMLS:C0175447 {source="BIRNLEX:1131"} xref: Wikipedia:Superior_salivatory_nucleus is_a: UBERON:0000126 ! cranial nerve nucleus is_a: UBERON:0004133 ! salivatory nucleus is_a: UBERON:0007635 ! nucleus of medulla oblongata relationship: BFO:0000050 UBERON:0003023 ! part of pontine tegmentum relationship: RO:0002495 UBERON:0010125 ! immediate transformation of future superior salivatory nucleus property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/6/6b/Gray788.png" xsd:anyURI [Term] id: UBERON:0002165 name: endocardium namespace: uberon def: "The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers[GO]." [GO:0003157] synonym: "endocardial lining" EXACT [EMAPA:32686] synonym: "endocardial tissue" EXACT [EMAPA:17868] synonym: "heart endocardium" EXACT [] xref: AAO:0010408 xref: BTO:0000387 xref: CALOHA:TS-2075 xref: EFO:0000821 xref: EHDAA2:0004153 xref: EMAPA:17868 xref: EMAPA:32686 xref: EV:0100021 xref: FMA:7280 xref: GAID:550 xref: galen:Endocardium xref: MA:0000076 xref: MAT:0000455 xref: MESH:D004699 xref: NCIT:C13004 xref: SCTID:362013006 xref: TAO:0001320 xref: UMLS:C0014124 {source="ncithesaurus:Endocardium"} xref: VHOG:0000084 xref: Wikipedia:Endocardium xref: XAO:0000066 xref: ZFA:0001320 is_a: UBERON:0002523 ! tunica intima is_a: UBERON:0005983 ! heart layer relationship: BFO:0000051 UBERON:0005316 ! has part endocardial endothelium relationship: RO:0002495 UBERON:0007280 {source="Bgee:AN"} ! immediate transformation of presumptive endocardium property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/6/6c/Gray493.png" xsd:anyURI [Term] id: UBERON:0002166 name: endocardium of atrium namespace: uberon def: "Endocardium that is part of the atrium." [ZFIN:curator] synonym: "atrial endocardium" EXACT [] synonym: "atrium endocardium" EXACT [] synonym: "atrium of heart endocardium" EXACT [OBOL:automatic] synonym: "Cardiac atria endocardium" EXACT [OBOL:automatic] synonym: "cardiac atrium endocardium" EXACT [OBOL:automatic] synonym: "endocardium of atrium of heart" EXACT [OBOL:automatic] synonym: "endocardium of Cardiac atria" EXACT [OBOL:automatic] synonym: "endocardium of cardiac atrium" EXACT [OBOL:automatic] synonym: "endocardium of heart atrium" EXACT [OBOL:automatic] synonym: "heart atrium endocardium" EXACT [OBOL:automatic] xref: EMAPA:32745 xref: FMA:7284 xref: MA:0000077 xref: SCTID:192001005 xref: TAO:0002169 xref: VHOG:0000606 xref: ZFA:0001614 is_a: UBERON:0002165 ! endocardium intersection_of: UBERON:0002165 ! endocardium intersection_of: BFO:0000050 UBERON:0002081 ! part of cardiac atrium relationship: BFO:0000050 UBERON:0002081 ! part of cardiac atrium relationship: RO:0002433 UBERON:0002081 ! contributes to morphology of cardiac atrium [Term] id: UBERON:0002167 name: right lung namespace: uberon def: "Lung which consists of the right upper lobe, middle lobe and right lower lobe.[FMA]." [FMA:FMA, Wikipedia:Right_lung] xref: EHDAA2:0001730 xref: EHDAA:4969 xref: EMAPA:17661 xref: FMA:7309 xref: MA:0000426 xref: NCIT:C33483 xref: SCTID:361967000 xref: UMLS:C0225706 {source="ncithesaurus:Right_Lung"} xref: VHOG:0000301 xref: Wikipedia:Right_lung is_a: UBERON:0002048 ! lung intersection_of: UBERON:0002048 ! lung intersection_of: BSPO:0000121 UBERON:0000170 ! in right side of pair of lungs relationship: BSPO:0000121 UBERON:0000170 ! in right side of pair of lungs property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/3/32/Gray972.png" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.4/3d-vh-f-lung.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.4/3d-vh-m-lung.glb" xsd:anyURI [Term] id: UBERON:0002168 name: left lung namespace: uberon def: "Lung which consists of the left upper lobe and left lower lobe.[FMA]." [FMA:FMA, Wikipedia:Left_lung] xref: EHDAA2:0000943 xref: EHDAA:4947 xref: EMAPA:17653 xref: FMA:7310 xref: MA:0000425 xref: NCIT:C32967 xref: SCTID:361982005 xref: UMLS:C0225730 {source="ncithesaurus:Left_Lung"} xref: VHOG:0000618 xref: Wikipedia:Left_lung is_a: UBERON:0002048 ! lung intersection_of: UBERON:0002048 ! lung intersection_of: BSPO:0000120 UBERON:0000170 ! in left side of pair of lungs relationship: BSPO:0000120 UBERON:0000170 ! in left side of pair of lungs property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/d/dd/Gray973.png" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.4/3d-vh-f-lung.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.4/3d-vh-m-lung.glb" xsd:anyURI [Term] id: UBERON:0002190 name: subcutaneous adipose tissue namespace: uberon def: "A portion of adipose tissue that is part of the hypodermis, beneath the dermis." [http://orcid.org/0000-0002-6601-2165] synonym: "fatty layer of subcutaneous tissue" EXACT [FMA:74315] synonym: "hypodermis fat layer" EXACT [MP:0011156] synonym: "subcutaneous fat layer" EXACT [MP:0011156] xref: BTO:0004042 xref: EMAPA:35829 xref: FMA:74315 xref: MA:0000473 is_a: UBERON:0001013 ! adipose tissue is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0001013 ! adipose tissue intersection_of: BFO:0000050 UBERON:0002072 ! part of hypodermis relationship: BFO:0000050 UBERON:0002072 ! part of hypodermis relationship: RO:0002433 UBERON:0002072 ! contributes to morphology of hypodermis [Term] id: UBERON:0002193 name: hemolymphoid system namespace: uberon def: "Anatomical cluster consisting of the hematopoietic system and the lymphoid system, or its analogs." [http://orcid.org/0000-0002-6601-2165] synonym: "hematolymphoid system" EXACT [] synonym: "lymphomyeloid complex" EXACT [] xref: CALOHA:TS-2018 xref: EHDAA2:0004615 xref: EMAPA:18765 xref: FMA:74562 xref: MA:0000013 is_a: UBERON:0000467 {source="MA"} ! anatomical system relationship: RO:0002160 NCBITaxon:33213 ! only in taxon Bilateria [Term] id: UBERON:0002199 name: integument namespace: uberon def: "The dermis, epidermis and hypodermis." [Wikipedia:Integument] synonym: "dermis plus epidermis plus hypodermis" EXACT [] synonym: "skin and subcutaneous tissue" EXACT [] synonym: "skin plus hypodermis" EXACT [] synonym: "the integument" EXACT [FMA:74657] xref: AAO:0000239 xref: BTO:0000634 xref: EMAPA:37504 {source="MA:th"} xref: FMA:74657 xref: galen:Integument xref: TAO:0000368 xref: VSAO:0000029 xref: Wikipedia:Integument xref: ZFA:0000368 is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0010314 ! structure with developmental contribution from neural crest is_a: UBERON:0011216 {source="FMA"} ! organ system subdivision relationship: BFO:0000050 UBERON:0002416 {source="FMA"} ! part of integumental system relationship: BFO:0000051 UBERON:0002072 ! has part hypodermis relationship: BFO:0000051 UBERON:0002097 ! has part skin of body relationship: RO:0002007 UBERON:0000468 ! bounding layer of multicellular organism relationship: RO:0002160 NCBITaxon:7711 ! only in taxon Chordata property_value: IAO:0000232 "in FMA intergument = skin+superficial fascia(hypodermis), skin=dermis+epidermis+hair_nail. Note that the definition provided here excludes the more general sense of the term 'integument' used in invertebrates; consider 'integumental system'. Note that the VSAO class appears to include adnexa by its definition." xsd:string [Term] id: UBERON:0002200 name: vasculature of head namespace: uberon def: "Vasculature that is part of a head [Automatically generated definition]." [OBOL:automatic] synonym: "adult head vascular network" EXACT [OBOL:automatic] synonym: "adult head vasculature" EXACT [OBOL:automatic] synonym: "cranial vasculature" EXACT [] synonym: "head vascular network" EXACT [OBOL:automatic] synonym: "vascular network of adult head" EXACT [OBOL:automatic] synonym: "vascular network of head" EXACT [OBOL:automatic] synonym: "vasculature of adult head" EXACT [OBOL:automatic] xref: EFO:0003656 xref: FMA:74710 xref: TAO:0001267 xref: XAO:0004152 xref: ZFA:0001267 is_a: UBERON:0002049 ! vasculature intersection_of: UBERON:0002049 ! vasculature intersection_of: BFO:0000050 UBERON:0000033 ! part of head relationship: BFO:0000050 UBERON:0000033 ! part of head [Term] id: UBERON:0002201 name: vasculature of trunk namespace: uberon def: "A vasculature that is part of a trunk [Automatically generated definition]." [OBOL:automatic] synonym: "torso vascular network" EXACT [OBOL:automatic] synonym: "torso vasculature" EXACT [OBOL:automatic] synonym: "trunk vascular network" EXACT [OBOL:automatic] synonym: "trunk vasculature" EXACT [] synonym: "vascular network of torso" EXACT [OBOL:automatic] synonym: "vascular network of trunk" EXACT [OBOL:automatic] synonym: "vasculature of torso" EXACT [OBOL:automatic] xref: FMA:74712 xref: TAO:0005024 xref: ZFA:0005024 is_a: UBERON:0002049 ! vasculature intersection_of: UBERON:0002049 ! vasculature intersection_of: BFO:0000050 UBERON:0002100 ! part of trunk relationship: BFO:0000050 UBERON:0002100 ! part of trunk [Term] id: UBERON:0002203 name: vasculature of eye namespace: uberon def: "Vasculature that is part of the eye region." [https://sourceforge.net/tracker/?func=detail&aid=3489658&group_id=76834&atid=994726, OBOL:automatic] synonym: "eye vascular network" EXACT [OBOL:automatic] synonym: "ocular blood vessel" EXACT [ZFA:0007057] synonym: "ocular vasculature" EXACT [] synonym: "vascular network of eye" EXACT [OBOL:automatic] xref: FMA:74743 xref: SCTID:123846009 xref: TAO:0007057 xref: ZFA:0007057 is_a: UBERON:0002200 ! vasculature of head is_a: UBERON:0006876 ! vasculature of organ intersection_of: UBERON:0002049 ! vasculature intersection_of: BFO:0000050 UBERON:0000019 ! part of camera-type eye relationship: BFO:0000050 UBERON:0000019 ! part of camera-type eye relationship: RO:0002202 UBERON:0003314 {source="ISBN:0781772214"} ! develops from eye mesenchyme property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI [Term] id: UBERON:0002204 name: musculoskeletal system namespace: uberon def: "Anatomical system that consists of the muscular and skeletal systems." [https://github.com/obophenotype/uberon/issues/77, VSAO:0000031, VSAO:curator] synonym: "musculo-skeletal system" EXACT [] xref: AAO:0010546 xref: CALOHA:TS-1311 xref: EMAPA:32714 xref: EV:0100139 xref: FMA:7482 xref: GAID:98 xref: MA:0002418 xref: MESH:D009141 xref: NCIT:C12754 xref: SCTID:278858007 xref: UMLS:C0026860 {source="ncithesaurus:Musculoskeletal_System"} xref: VHOG:0001275 xref: VSAO:0000031 xref: Wikipedia:Musculoskeletal_system xref: XAO:0000168 is_a: UBERON:0000467 ! anatomical system disjoint_from: UBERON:0002294 ! biliary system disjoint_from: UBERON:0002330 ! exocrine system disjoint_from: UBERON:0002390 ! hematopoietic system disjoint_from: UBERON:0002405 ! immune system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:8450002 ! excretory system relationship: BFO:0000051 UBERON:0000383 ! has part musculature of body relationship: BFO:0000051 UBERON:0001434 ! has part skeletal system relationship: RO:0002216 GO:0040011 ! capable of part of locomotion relationship: RO:0002492 UBERON:0000066 ! existence ends during fully formed stage property_value: x_1.1:contributor https://github.com/cmungall [Term] id: UBERON:0002213 name: cartilaginous joint namespace: uberon def: "Nonsynovial joint in which the articulating bones or cartilages are connected by cartilage. Examples: Spheno-occipital synchondrosis, first sternocostal joint, pubic symphysis.[FMA]." [FMA:FMA, Wikipedia:Cartilaginous_joint] synonym: "articulatio cartilaginea" EXACT [] xref: EMAPA:36581 xref: FMA:7496 xref: MA:0000320 xref: SCTID:58442004 xref: TAO:0005155 xref: Wikipedia:Cartilaginous_joint xref: ZFA:0005155 is_a: UBERON:0011134 {source="FMA"} ! nonsynovial joint intersection_of: UBERON:0011134 ! nonsynovial joint intersection_of: RO:0002473 UBERON:0002418 ! composed primarily of cartilage tissue relationship: RO:0002473 UBERON:0002418 ! composed primarily of cartilage tissue [Term] id: UBERON:0002217 name: synovial joint namespace: uberon def: "Joint in which the articulating bones or cartilages are connected by an articular capsule which encloses a synovial membrane and a synovial cavity. Examples: Temporomandibular joint, knee joint.[FMA]." [FMA:7501, Wikipedia:Synovial_joint] synonym: "articulatio synoviale" EXACT [] synonym: "diarthrosis" EXACT [] synonym: "diarthrosis joint" EXACT [] xref: AEO:0000183 xref: CALOHA:TS-2138 xref: EHDAA2:0003183 xref: FMA:7501 xref: galen:SynovialJoint xref: MA:0000322 xref: NCIT:C32461 xref: SCTID:113234001 xref: TAO:0005153 xref: Wikipedia:Synovial_joint xref: ZFA:0005153 is_a: UBERON:0000982 ! skeletal joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: RO:0002219 UBERON:0001484 ! surrounded by articular capsule disjoint_from: UBERON:0011134 ! nonsynovial joint relationship: RO:0002160 NCBITaxon:7742 ! only in taxon Vertebrata relationship: RO:0002219 UBERON:0001484 ! surrounded by articular capsule [Term] id: UBERON:0002224 name: thoracic cavity namespace: uberon def: "The part of the coelemic cavity lumen that is enclosed by the walls of the thorax." [UBERON:cjm, Wikipedia:Thoracic_cavity] synonym: "cavity of chest" EXACT [] synonym: "cavity of thorax" EXACT [] synonym: "chest cavity" EXACT [] synonym: "pectoral cavity" EXACT [] synonym: "space of thoracic compartment" EXACT [FMA:7565] synonym: "thoracic lumen" EXACT [] xref: EMAPA:36497 xref: FMA:7565 xref: GAID:93 xref: MA:0000032 xref: MESH:D035423 xref: NCIT:C12905 xref: SCTID:243949006 xref: UMLS:C0230139 {source="ncithesaurus:Thoracic_Cavity"} xref: Wikipedia:Thoracic_cavity is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: BFO:0000050 UBERON:0002323 ! part of coelemic cavity lumen intersection_of: RO:0002572 UBERON:0000915 ! luminal space of thoracic segment of trunk relationship: BFO:0000050 UBERON:0002323 ! part of coelemic cavity lumen relationship: RO:0002572 UBERON:0000915 ! luminal space of thoracic segment of trunk property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/c/ce/Gray846.png" xsd:anyURI property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/e/ee/Scheme_body_cavities-en.svg" xsd:anyURI [Term] id: UBERON:0002240 name: spinal cord namespace: uberon def: "Part of the central nervous system located in the vertebral canal continuous with and caudal to the brain; demarcated from brain by plane of foramen magnum. It is composed of an inner core of gray matter in which nerve cells predominate, and an outer layer of white matter in which myelinated nerve fibers predominate, and surrounds the central canal. (CUMBO)." [BIRNLEX:1709] xref: AAO:0010151 xref: BAMS:SP xref: BAMS:Spinal xref: BIRNLEX:1709 xref: BM:SpC xref: BTO:0001279 xref: CALOHA:TS-0953 xref: DHBA:12890 xref: DMBA:17651 xref: EFO:0000110 xref: EHDAA2:0001255 xref: EHDAA:2863 xref: EMAPA:17577 xref: EV:0100316 xref: FMA:7647 xref: GAID:695 xref: MA:0000216 xref: MAT:0000183 xref: MESH:D013116 xref: MIAA:0000183 xref: NCIT:C12464 xref: neuronames:22 {source="BIRNLEX:1709"} xref: SCTID:180959008 xref: TAO:0000075 xref: UMLS:C0037925 {source="ncithesaurus:Spinal_Cord", source="BIRNLEX:1709"} xref: VHOG:0000601 xref: Wikipedia:Spinal_cord xref: XAO:0000020 xref: ZFA:0000075 is_a: UBERON:0000489 ! cavitated compound organ is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0005174 ! dorsal region element is_a: UBERON:0010314 ! structure with developmental contribution from neural crest relationship: BFO:0000050 UBERON:0001017 ! part of central nervous system relationship: BFO:0000051 CL:0005000 {source="ZFA"} ! has part spinal cord interneuron relationship: RO:0002202 UBERON:0003076 ! develops from posterior neural tube relationship: RO:0002254 UBERON:0003853 ! has developmental contribution from spinal cord neural crest relationship: RO:0002495 UBERON:0006241 ! immediate transformation of future spinal cord property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/5/58/Spinal_cord_direv.svg" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Spinal_Cord.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Spinal_Cord.glb" xsd:anyURI [Term] id: UBERON:0002241 name: chondrocranium namespace: uberon def: "Endoskeletal elements that encase the brain, nose, inner ear[cjm]. that part of the neurocranium formed by endochondral ossification and comprising the bones of the base of the skull[TFD]." [http://medical-dictionary.thefreedictionary.com/chondrocranium, Wikipedia:Chondrocranium] xref: AAO:0010169 xref: EHDAA2:0000243 xref: EMAPA:17681 xref: TAO:0001424 xref: VHOG:0000288 xref: Wikipedia:Chondrocranium xref: ZFA:0001424 is_a: UBERON:0011159 ! primary subdivision of cranial skeletal system relationship: RO:0002131 UBERON:0001703 ! overlaps neurocranium [Term] id: UBERON:0002257 name: ventral horn of spinal cord namespace: uberon def: "The ventral grey column of the spinal cord[MP]. The neurons of the ventral region of the mature spinal cord participate in motor output[GO]." [GO:0021517, https://sourceforge.net/tracker/?group_id=36855&atid=440764, MP:0005112, Wikipedia:Anterior_horn_of_spinal_cord] synonym: "anterior gray column of spinal cord" EXACT [FMA:256541] synonym: "anterior gray horn of spinal cord" EXACT [FMA:256541] synonym: "anterior grey column of spinal cord" EXACT [] synonym: "anterior horn" EXACT [BIRNLEX:2668] synonym: "spinal cord anterior horn" EXACT [BIRNLEX:2668] synonym: "spinal cord ventral horn" EXACT [] synonym: "ventral gray column of spinal cord" EXACT [FMA:256541] synonym: "ventral gray matter of spinal cord" EXACT [FMA:256541] synonym: "ventral grey column of spinal cord" EXACT [] synonym: "ventral grey horn" EXACT [BIRNLEX:2668] synonym: "ventral horn spinal cord" EXACT [ZFA:0000702] synonym: "ventral region of spinal cord" EXACT [] synonym: "ventral spinal cord" EXACT [] xref: BAMS:VH xref: BIRNLEX:2668 xref: BTO:0005151 xref: EMAPA:18575 xref: EMAPA:35794 xref: FMA:256541 xref: MA:0001134 xref: NCIT:C33859 xref: neuronames:1751 xref: SCTID:279443000 xref: TAO:0000702 xref: UMLS:C0228569 {source="BIRNLEX:2668"} xref: UMLS:C0228590 {source="ncithesaurus:Ventral_Horn_of_the_Spinal_Cord"} xref: VHOG:0001288 xref: Wikipedia:Anterior_horn_of_spinal_cord xref: ZFA:0000702 is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0016550 ! spinal cord column relationship: BFO:0000051 CL:0000100 ! has part motor neuron relationship: BSPO:0000126 UBERON:0002315 {source="FMA-abduced-lr"} ! in lateral side of gray matter of spinal cord relationship: RO:0002433 UBERON:0002315 ! contributes to morphology of gray matter of spinal cord [Term] id: UBERON:0002275 name: reticular formation namespace: uberon def: "A composite substructure of the brainstem that consists of the midbrain reticular formation, the pontine reticular formation and the medullary reticular formation ( Carpenter-1983 )." [NeuroNames:1223] synonym: "brain stem reticular formation" EXACT [NeuroNames:1223] synonym: "brainstem reticular formation" EXACT [MA:0003185, NeuroNames:1223] synonym: "reticular formation (classical)" EXACT [NeuroNames:1223] synonym: "reticular formation of the brainstem" EXACT [NeuroNames:1223] xref: BAMS:RET xref: EMAPA:35188 xref: FMA:77719 xref: MA:0003185 xref: MESH:D012154 xref: neuronames:1223 xref: NLX:143558 xref: SCTID:361552007 xref: Wikipedia:Reticular_formation is_a: UBERON:0002616 ! regional part of brain relationship: BFO:0000050 UBERON:0002298 ! part of brainstem property_value: IAO:0000232 "this class denotes the generic structure, and not a specific one such as medullary or pontine reticular formation." xsd:string property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/9/9b/Gray701.png" xsd:anyURI [Term] id: UBERON:0002294 name: biliary system namespace: uberon def: "Organ system subdivision that consists of the organs and ducts that are involved in the production and transportation of bile. In most species this is the gallbladder and the bile ducts (biliary tree)." [Wikipedia:Biliary_system] synonym: "biliary apparatus" EXACT [FMA:79646] xref: FMA:79646 xref: GAID:279 xref: MA:0001273 xref: MESH:D001659 xref: NCIT:C12678 xref: SCTID:361354009 xref: Wikipedia:Biliary_system is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0011216 ! organ system subdivision intersection_of: UBERON:0011216 ! organ system subdivision intersection_of: BFO:0000051 UBERON:0001173 ! has part biliary tree intersection_of: RO:0002215 GO:0006699 ! capable of bile acid biosynthetic process intersection_of: RO:0002215 GO:0015721 ! capable of bile acid and bile salt transport disjoint_from: UBERON:0002330 ! exocrine system disjoint_from: UBERON:0002390 ! hematopoietic system disjoint_from: UBERON:0002405 ! immune system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:8450002 ! excretory system relationship: BFO:0000050 UBERON:0002423 ! part of hepatobiliary system relationship: BFO:0000051 UBERON:0001173 ! has part biliary tree relationship: RO:0002215 GO:0006699 ! capable of bile acid biosynthetic process relationship: RO:0002215 GO:0015721 ! capable of bile acid and bile salt transport property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/5/5d/Digestive_system_showing_bile_duct.png" xsd:anyURI [Term] id: UBERON:0002296 name: dorsal mesentery namespace: uberon def: "The mesentery that originates from the dorsal side of the peritoneal cavity[ZFA]." [Wikipedia:Dorsal_mesentery, Wikipedia:Mesentery#Development, ZFIN:curator] xref: EHDAA2:0004560 xref: EHDAA:3019 xref: EHDAA:3033 xref: EHDAA:3921 xref: EHDAA:3934 xref: EHDAA:3957 xref: EHDAA:3971 xref: FMA:79795 xref: SCTID:308823000 xref: TAO:0005130 xref: Wikipedia:Mesentery#Development xref: ZFA:0005130 is_a: UBERON:0006598 ! presumptive structure relationship: BFO:0000050 UBERON:0009664 {source="EHDAA2"} ! part of gut mesentery relationship: RO:0002387 UBERON:0002095 ! has potential to develop into mesentery property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/8/85/Gray985.png" xsd:anyURI [Term] id: UBERON:0002298 name: brainstem namespace: uberon def: "Stalk-like part of the brain that includes amongst its parts the medulla oblongata of the hindbrain and the tegmentum of the midbrain[ZFA,MP,generalized]." [ISBN:0471888893, MP:0005277, Wikipedia:Brainstem, ZFA:0001707] synonym: "brain stem" EXACT [ABA:BS] xref: BAMS:BS xref: BIRNLEX:1565 xref: BTO:0000146 xref: CALOHA:TS-0093 xref: EFO:0001962 xref: EMAPA:32678 xref: EV:0100241 xref: FMA:79876 xref: MA:0000169 xref: MBA:343 xref: MESH:D001933 xref: NCIT:C12441 xref: neuronames:236 {source="BIRNLEX:1565"} xref: SCTID:180925009 xref: TAO:0002156 xref: UMLS:C0006121 {source="BIRNLEX:1565", source="ncithesaurus:Brain_Stem"} xref: VHOG:0001457 xref: Wikipedia:Brainstem xref: ZFA:0001707 is_a: UBERON:0002616 ! regional part of brain relationship: BFO:0000051 UBERON:0001896 ! has part medulla oblongata relationship: BFO:0000051 UBERON:0001943 ! has part midbrain tegmentum relationship: RO:0002150 UBERON:0002240 ! continuous with spinal cord relationship: RO:0002433 UBERON:0000955 ! contributes to morphology of brain property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/b/b7/Gray719.png" xsd:anyURI [Term] id: UBERON:0002302 name: myocardium of atrium namespace: uberon def: "The atrial part of middle layer of the heart, comprised of involuntary muscle." [ISBN:0-683-40008-8, MP:0010493] synonym: "atrial myocardium" EXACT [ZFA:0001374] synonym: "atrium myocardium" EXACT [] xref: EFO:0003087 xref: EMAPA:32746 xref: FMA:83509 xref: MA:0000081 xref: SCTID:191910002 xref: TAO:0001374 xref: VHOG:0000602 xref: ZFA:0001374 is_a: UBERON:0002349 ! myocardium intersection_of: UBERON:0002349 ! myocardium intersection_of: BFO:0000050 UBERON:0002081 ! part of cardiac atrium relationship: BFO:0000050 UBERON:0002081 ! part of cardiac atrium relationship: RO:0002433 UBERON:0002081 ! contributes to morphology of cardiac atrium [Term] id: UBERON:0002308 name: nucleus of brain namespace: uberon def: "A neural nucleus that is part of the brain." [http://orcid.org/0000-0002-6601-2165] synonym: "brain nucleus" EXACT [] xref: EMAPA:35185 xref: FMA:83840 xref: MA:0000811 xref: NCIT:C49346 xref: SCTID:426465002 xref: UMLS:C1706993 {source="ncithesaurus:Brain_Nucleus"} xref: ZFA:0005575 is_a: UBERON:0000125 ! neural nucleus intersection_of: UBERON:0000125 ! neural nucleus intersection_of: BFO:0000050 UBERON:0000955 ! part of brain relationship: BFO:0000050 UBERON:0003528 ! part of brain gray matter [Term] id: UBERON:0002315 name: gray matter of spinal cord namespace: uberon def: "The ridge-shaped grey matter of the spinal cord that extends longitudunally through the center of each half of the spinal cord, and are largely or entirely composed of nerve cell bodies and their dendrites and some supportive tissue." [MP:0008503] synonym: "gray matter of spinal cord" EXACT [OBOL:automatic] synonym: "gray substance of spinal cord" EXACT [FMA:256580] synonym: "grey matter of spinal cord" EXACT [] synonym: "grey substance of spinal cord" EXACT [] synonym: "spinal cord gray matter" EXACT [OBOL:automatic] synonym: "spinal cord grey matter" EXACT [] synonym: "spinal cord grey substance" EXACT [OBOL:automatic] xref: BAMS:Scgrey xref: DHBA:146035048 xref: EMAPA:35792 xref: FMA:256580 xref: MA:0000002 xref: NCIT:C32696 xref: neuronames:2619 xref: NLXANAT:100204 xref: SCTID:279441003 xref: UMLS:C0475853 {source="ncithesaurus:Gray_Matter_of_the_Spinal_Cord"} is_a: UBERON:0002020 ! gray matter intersection_of: UBERON:0002020 ! gray matter intersection_of: BFO:0000050 UBERON:0002240 ! part of spinal cord relationship: BFO:0000050 UBERON:0002240 ! part of spinal cord relationship: RO:0002433 UBERON:0002240 ! contributes to morphology of spinal cord [Term] id: UBERON:0002323 name: coelemic cavity lumen namespace: uberon def: "The cavity within the body of all animals higher than the coelenterates and certain primitive worms, formed by the splitting of the embryonic mesoderm into two layers. In mammals it forms the peritoneal, pleural, and pericardial cavities." [BTO:0001707] synonym: "coelomic cavity" EXACT [EHDAA2:0000267] synonym: "coelomic cavity lumen" EXACT [EHDAA2:0000267] synonym: "main body cavity" EXACT [] synonym: "space of body compartment" EXACT [FMA:85006] xref: AEO:0000186 xref: BTO:0001707 xref: EHDAA2:0000267 xref: FMA:85006 xref: galen:BodyCavity xref: NCIT:C25444 xref: RETIRED_EHDAA2:0003186 xref: SCTID:361348008 xref: TAO:0001438 xref: UMLS:C0333343 {source="ncithesaurus:Cavity"} xref: ZFA:0001438 is_a: UBERON:0002553 ! anatomical cavity relationship: RO:0002494 UBERON:0003886 ! transformation of future coelemic cavity lumen relationship: RO:0002572 UBERON:0011997 ! luminal space of coelom [Term] id: UBERON:0002324 name: muscle of back namespace: uberon def: "Any muscle organ that is part of a back [Automatically generated definition]." [OBOL:automatic] synonym: "back muscle" EXACT [] synonym: "back muscle organ" EXACT [OBOL:automatic] synonym: "muscle organ of back" EXACT [OBOL:automatic] xref: EMAPA:35161 xref: FMA:85216 xref: MA:0000496 is_a: UBERON:0001774 ! skeletal muscle of trunk is_a: UBERON:0005174 ! dorsal region element intersection_of: UBERON:0014892 ! skeletal muscle organ, vertebrate intersection_of: BFO:0000050 UBERON:0001137 ! part of dorsum relationship: BFO:0000050 UBERON:0004469 {source="prolog"} ! part of musculature of back [Term] id: UBERON:0002325 name: epithelium of urethra namespace: uberon def: "The urethra is a renal system organ that carries urine from the bladder to outside the body. The epithelium is the tubular, planar layer of cells through which the urine passes.." [GO:0061071] synonym: "epithelial tissue of urethra" EXACT [OBOL:automatic] synonym: "urethra epithelial tissue" EXACT [OBOL:automatic] synonym: "urethra epithelium" EXACT [] xref: EMAPA:31518 xref: FMA:85275 xref: MA:0001686 xref: NCIT:C49309 xref: UMLS:C1710584 {source="ncithesaurus:Urethra_Epithelium"} is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure is_a: UBERON:0003914 {source="GO"} ! epithelial tube is_a: UBERON:0005911 ! endo-epithelium is_a: UBERON:0006555 ! excretory tube is_a: UBERON:0012275 ! meso-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: BFO:0000050 UBERON:0000057 ! part of urethra relationship: BFO:0000050 UBERON:0000057 ! part of urethra [Term] id: UBERON:0002326 name: lamina propria of urethra namespace: uberon def: "A lamina propria that is part of a urethra [Automatically generated definition]." [OBOL:automatic] synonym: "lamina propria mucosa of urethra" EXACT [OBOL:automatic] synonym: "lamina propria mucosae of urethra" EXACT [OBOL:automatic] synonym: "urethra lamina propria" EXACT [] synonym: "urethra lamina propria mucosa" EXACT [OBOL:automatic] synonym: "urethra lamina propria mucosae" EXACT [OBOL:automatic] xref: EMAPA:37785 {source="MA:th"} xref: FMA:85276 xref: MA:0001689 is_a: UBERON:0000030 ! lamina propria is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0000030 ! lamina propria intersection_of: BFO:0000050 UBERON:0000057 ! part of urethra relationship: BFO:0000050 UBERON:0000057 ! part of urethra [Term] id: UBERON:0002328 name: notochord namespace: uberon def: "A flexible rod-shaped body found in embryos of all chordates. It is composed of cells derived from the mesoderm and defines the primitive axis of the embryo. In some chordates, it persists throughout life as the main axial support of the body, while in most vertebrates it becomes the nucleus pulposus of the intervertebral disc. The notochord is found ventral to the neural tube." [http://tolweb.org/Chordata/2499, https://github.com/obophenotype/uberon/issues/25, https://github.com/obophenotype/uberon/issues/271, ISBN:0815318960, Wikipedia:Notochord] synonym: "embryonic notocord" EXACT [] synonym: "notocord" EXACT [ZFA:0000135] xref: AAO:0000327 xref: BTO:0001768 xref: CALOHA:TS-0690 xref: EHDAA2:0001277 xref: EHDAA:1241 xref: EHDAA:6021 xref: EMAPA:16191 xref: EV:0100002 xref: FMA:85521 xref: GAID:1311 xref: http://evolution.berkeley.edu/evolibrary/images/history/notochords.jpg xref: MAT:0000281 xref: MESH:D009672 xref: NCIT:C12463 xref: SCTID:308820002 xref: TAO:0000135 xref: UMLS:C0028439 {source="ncithesaurus:Notochord"} xref: VHOG:0000199 xref: VSAO:0000032 xref: Wikipedia:Notochord xref: XAO:0000055 xref: ZFA:0000135 is_a: UBERON:0000062 {source="PMID:15890825"} ! organ is_a: UBERON:0000481 {source="VSAO"} ! multi-tissue structure is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0004121 ! ectoderm-derived structure relationship: BFO:0000050 NCBITaxon:6072 ! part of Eumetazoa relationship: BFO:0000050 UBERON:0000922 {gci_filler="NCBITaxon:40674", gci_relation="BFO:0000050"} ! part of embryo relationship: BFO:0000050 UBERON:0011137 ! part of axial skeletal system relationship: BSPO:0000098 UBERON:0001555 ! dorsal to digestive tract relationship: BSPO:0000102 UBERON:0001049 ! ventral to neural tube relationship: RO:0002160 NCBITaxon:7711 {source="http://tolweb.org/Chordata/2499"} ! only in taxon Chordata relationship: RO:0002202 UBERON:0004880 {source="ZFA"} ! develops from chordamesoderm relationship: RO:0002202 UBERON:0006267 {source="EHDAA2"} ! develops from notochordal plate relationship: RO:0002488 UBERON:0000068 ! existence starts during embryo stage relationship: RO:0003000 PR:000014841 ! produces sonic hedgehog protein property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png" xsd:anyURI property_value: x_1.1:contributor https://github.com/cmungall property_value: x_1.1:contributor https://github.com/wdahdul [Term] id: UBERON:0002329 name: somite namespace: uberon def: "Somites are spheres of epithelial cells that form sequentially along the anterior-posterior axis of the embryo through mesenchymal to epithelial transition of the presomitic mesoderm." [DOI:10.1111/j.1439-0426.2012.01987.x, Wikipedia:Somite] xref: AAO:0010569 xref: AEO:0001015 xref: BTO:0001558 xref: EHDAA2:0003436 xref: EHDAA:366 xref: EHDAA:699 xref: EMAPA:31169 xref: FMA:85522 xref: GAID:1306 xref: MAT:0000068 xref: MESH:D019170 xref: MIAA:0000068 xref: NCIT:C34302 xref: TAO:0000155 xref: UMLS:C0376449 {source="ncithesaurus:Somite"} xref: VHOG:0000191 xref: Wikipedia:Somite xref: XAO:0000058 xref: ZFA:0000155 is_a: UBERON:0005423 ! developing anatomical structure is_a: UBERON:0007503 {source="EHDAA2"} ! epithelial vesicle relationship: RO:0002160 NCBITaxon:7711 {source="GOTAX:0000352"} ! only in taxon Chordata relationship: RO:0002202 UBERON:0003059 {source="ZFA"} ! develops from presomitic mesoderm property_value: IAO:0000232 "EDITOR_NOTE currently classified as an epithelial vesicle, consistent with EHDAA2 and https://github.com/obophenotype/uberon/wiki/The-neural-crest. Consider making 'somitic mesoderm' a separate term and correlate with regionalization processes. Consider moving ZFA term to 'trunk somite' as it is part of the trunk" xsd:string property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png" xsd:anyURI [Term] id: UBERON:0002330 name: exocrine system namespace: uberon def: "Anatomical system that consists of the glands and parts of glands that produce exocrine secretions and help to integrate and control bodily metabolic activity. Exocrine glands are glands that secrete their products (hormones) into ducts (duct glands). They are the counterparts to endocrine glands, which secrete their products (hormones) directly into the bloodstream (ductless glands) or release hormones (paracrines) that affect only target cells nearby the release site. [Wikipedia]." [Wikipedia:Exocrine_gland] synonym: "exocrine glandular system" EXACT [EHDAA2:0002225] xref: CALOHA:TS-2057 xref: EHDAA2:0002225 xref: EMAPA:35329 xref: FMA:85539 xref: MA:0002411 xref: NCIT:C12957 xref: UMLS:C1516995 {source="ncithesaurus:Exocrine_System"} xref: Wikipedia:Exocrine_gland xref: WikipediaCategory:Exocrine_system is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000467 ! anatomical system disjoint_from: UBERON:0002390 ! hematopoietic system disjoint_from: UBERON:0002405 ! immune system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:8450002 ! excretory system relationship: RO:0002160 NCBITaxon:6072 ! only in taxon Eumetazoa relationship: RO:0002473 UBERON:0002365 ! composed primarily of exocrine gland relationship: RO:0002492 UBERON:0000066 ! existence ends during fully formed stage [Term] id: UBERON:0002331 name: umbilical cord namespace: uberon def: "The connecting cord from the developing embryo to the placenta." [ISBN:0-683-40008-8, MP:0001725, PMID:9144284, Wikipedia:Umbilical_cord] xref: BTO:0001415 xref: CALOHA:TS-1078 xref: EFO:0001415 xref: EHDAA2:0000312 xref: EHDAA:158 xref: EMAPA:26115 xref: EV:0100127 xref: FMA:85541 xref: GAID:517 xref: MAT:0000280 xref: MESH:D014470 xref: MIAA:0000280 xref: NCIT:C34320 xref: SCTID:280644003 xref: UMLS:C0041633 {source="ncithesaurus:Umbilical_Cord"} xref: Wikipedia:Umbilical_cord is_a: UBERON:0000478 ! extraembryonic structure relationship: RO:0002176 UBERON:0000922 ! connects embryo relationship: RO:0002176 UBERON:0001987 ! connects placenta relationship: RO:0002202 UBERON:0007806 ! develops from connecting stalk property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/f/f3/Umbilicalcord.jpg" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Placenta.glb" xsd:anyURI [Term] id: UBERON:0002333 name: pulmonary trunk namespace: uberon def: "An arterial trunk which is continuous with the heart and branches into the pulmonary arteries." [http://orcid.org/0000-0002-6601-2165] synonym: "pulmonary artery (trunk)" EXACT [] synonym: "trunk of pulmonary arterial tree" EXACT [] xref: EHDAA2:0001576 xref: EHDAA:9831 xref: EMAPA:17015 xref: FMA:8612 xref: galen:PulmonaryTrunk xref: MA:0002033 xref: NCIT:C116918 xref: VHOG:0001134 is_a: UBERON:0001637 {source="MA"} ! artery relationship: BFO:0000050 RO:0002577 ! part of system relationship: BFO:0000050 UBERON:0008886 ! part of pulmonary vascular system relationship: RO:0002150 UBERON:0000948 ! continuous with heart relationship: RO:0002150 UBERON:0002080 {gci_filler="NCBITaxon:40674", gci_relation="BFO:0000050"} ! continuous with heart right ventricle relationship: RO:0002170 UBERON:0002080 ! connected to heart right ventricle property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/d/db/Alveoli_diagram.png" xsd:anyURI [Term] id: UBERON:0002337 name: endometrial stroma namespace: uberon def: "The layer of connective tissue comprised of the endometrial lining of the uterus which fluctuates in thickness throughout the menstrual cycle." [ncithesaurus:Endometrial_Stroma] synonym: "endometrium stroma" EXACT [] synonym: "stroma of endometrium" EXACT [] xref: CALOHA:TS-1266 xref: EMAPA:35310 xref: FMA:86487 xref: MA:0002734 xref: NCIT:C32516 xref: SCTID:254115004 xref: UMLS:C0227849 {source="ncithesaurus:Endometrial_Stroma"} is_a: UBERON:0003891 ! stroma is_a: UBERON:0005156 ! reproductive structure intersection_of: UBERON:0003891 ! stroma intersection_of: BFO:0000050 UBERON:0001295 ! part of endometrium relationship: BFO:0000050 UBERON:0001295 ! part of endometrium [Term] id: UBERON:0002342 name: neural crest namespace: uberon def: "A specialized region of ectoderm found between the neural ectoderm (neural plate) and non-neural ectoderm and composed of highly migratory pluripotent cells that delaminate in early embryonic development from the dorsal neural tube and give rise to an astounding variety of differentiated cell types[MP]." [MP:0009846] xref: AAO:0010578 xref: BTO:0001764 xref: CALOHA:TS-0676 xref: EHDAA2:0004419 xref: EMAPA:32737 xref: FMA:86666 xref: GAID:1310 xref: MAT:0000066 xref: MESH:D009432 xref: MIAA:0000066 xref: NCIT:C34222 xref: neuronames:1366 xref: SCTID:361462002 xref: TAO:0000045 xref: UMLS:C0027789 {source="ncithesaurus:Neural_Crest"} xref: VHOG:0000057 xref: Wikipedia:Neural_crest xref: XAO:0000048 xref: ZFA:0000045 is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0010314 ! structure with developmental contribution from neural crest is_a: UBERON:0010316 ! germ layer / neural crest relationship: BFO:0000050 UBERON:0002346 {source="XAO", source="https://github.com/obophenotype/uberon/wiki/The-neural-crest"} ! part of neurectoderm relationship: RO:0002160 NCBITaxon:89593 ! only in taxon Craniata relationship: RO:0002202 UBERON:0003075 {source="BTO"} ! develops from neural plate relationship: RO:0002202 UBERON:0005062 {source="PMID:11523831"} ! develops from neural fold relationship: RO:0002473 CL:0000333 ! composed primarily of migratory neural crest cell relationship: RO:0002488 UBERON:0000110 {source="PMID:11523831"} ! existence starts during neurula stage property_value: IAO:0000232 "EDITOR_NOTE consider including subclasses for pre- and post- migratory (e.g. sheets/paths/streams)." xsd:string property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray644.png" xsd:anyURI property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png" xsd:anyURI [Term] id: UBERON:0002343 name: abdomen musculature namespace: uberon def: "Set of all muscles in abdomen." [OBOL:automatic] synonym: "abdominal musculature" EXACT [] synonym: "muscle group of abdomen" EXACT [FMA:71294] synonym: "muscles of abdomen" EXACT [FMA:71294] synonym: "musculature of abdomen" EXACT [] synonym: "musculature of abdominal wall" EXACT [FMA:86917] synonym: "set of muscles of abdomen" EXACT [FMA:71294] xref: FMA:71294 xref: FMA:86917 xref: TAO:0001327 xref: ZFA:0001327 is_a: UBERON:0004479 ! musculature of trunk intersection_of: UBERON:0001015 ! musculature intersection_of: BFO:0000050 UBERON:0000916 ! part of abdomen relationship: BFO:0000050 UBERON:0000916 ! part of abdomen property_value: IAO:0000232 "distinction between abdomen muscle and abdomen musculature" xsd:string [Term] id: UBERON:0002345 name: descending thoracic aorta namespace: uberon def: "The part of the aorta that extends from the arch of the aorta to the diaphragm, and from which arises numerous branches that supply oxygenated blood to the chest cage and the organs within the chest." [MP:0009868] xref: EFO:0002527 xref: EMAPA:18605 xref: FMA:87217 xref: MA:0002572 xref: SCTID:181301002 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0013522 ! subdivision of tube relationship: BFO:0000050 UBERON:0001514 ! part of descending aorta relationship: BFO:0000050 UBERON:0001515 ! part of thoracic aorta relationship: RO:0002433 UBERON:0001514 ! contributes to morphology of descending aorta relationship: RO:0002433 UBERON:0001515 ! contributes to morphology of thoracic aorta [Term] id: UBERON:0002346 name: neurectoderm namespace: uberon def: "Embryonic ectoderm that gives rise to nervous tissue." [Wikipedia:Neuroectoderm] synonym: "neural ectoderm" EXACT [] synonym: "neuroectoderm" EXACT [] xref: AAO:0011074 xref: BILA:0000039 xref: CALOHA:TS-1212 xref: EHDAA2:0001248 xref: EHDAA:1498 xref: EHDAA:255 xref: EMAPA:16073 xref: EV:0100004 xref: FMA:87657 xref: MAT:0000176 xref: MIAA:0000176 xref: NCIT:C34228 xref: TAO:0001120 xref: UMLS:C1518271 {source="ncithesaurus:Neuroectoderm"} xref: VHOG:0000150 xref: Wikipedia:Neuroectoderm xref: XAO:0000042 xref: ZFA:0001120 is_a: UBERON:0000923 ! germ layer is_a: UBERON:0004121 ! ectoderm-derived structure relationship: BFO:0000051 CL:0000133 ! has part neurectodermal cell [Term] id: UBERON:0002347 name: thoracic vertebra namespace: uberon def: "A thoracic vertebra endochondral element that is composed primarily of a bone tissue." [OBOL:automatic] synonym: "dorsal vertebra" EXACT [] synonym: "thorax vertebra" EXACT [OBOL:automatic] synonym: "vertebra of thorax" EXACT [OBOL:automatic] synonym: "vertebra thoracica" EXACT [] xref: EMAPA:18011 xref: FMA:9139 xref: GAID:244 xref: MA:0000314 xref: MESH:D013904 xref: NCIT:C12798 xref: SCTID:181821009 xref: UMLS:C0039987 {source="ncithesaurus:Thoracic_Vertebra"} xref: Wikipedia:Thoracic_vertebrae is_a: UBERON:0002412 ! vertebra is_a: UBERON:0003827 ! thoracic segment bone is_a: UBERON:0004247 ! bone of dorsum is_a: UBERON:0015008 ! thoracic vertebra endochondral element intersection_of: UBERON:0015008 ! thoracic vertebra endochondral element intersection_of: RO:0002473 UBERON:0002481 ! composed primarily of bone tissue relationship: RO:0002202 UBERON:0013507 ! develops from thoracic vertebra cartilage element property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/d/d2/Gray90.png" xsd:anyURI [Term] id: UBERON:0002348 name: epicardium namespace: uberon def: "A region of the serous membrane that forms the innermost layer of the pericardium and the outer surface of the heart." [http://orcid.org/0000-0002-6601-2165] synonym: "heart epicardium" EXACT [] synonym: "visceral serous pericardium of heart" EXACT [FMA:9461] synonym: "visceral serous pericardium proper" EXACT [FMA:9461] xref: AAO:0010409 xref: EHDAA2:0002202 xref: FMA:9461 xref: galen:Epicardium xref: NCIT:C13164 xref: TAO:0005057 xref: UMLS:C0225968 {source="ncithesaurus:Epicardium"} xref: VHOG:0000119 xref: Wikipedia:Epicardium xref: XAO:0000316 xref: ZFA:0005057 is_a: UBERON:0000481 ! multi-tissue structure is_a: UBERON:0004120 ! mesoderm-derived structure relationship: BFO:0000050 UBERON:0000948 {source="multiple"} ! part of heart relationship: BFO:0000050 UBERON:0002425 {source="FMA-inferred"} ! part of visceral serous pericardium relationship: RO:0002202 UBERON:0004160 ! develops from proepicardium relationship: RO:0002371 UBERON:0002349 {source="FMA"} ! attached to myocardium [Term] id: UBERON:0002349 name: myocardium namespace: uberon def: "The middle layer of the heart, comprised mainly of striated cardiac muscle fibers." [ISBN:0-683-40008-8, MP:0005329] synonym: "heart myocardium" EXACT [] synonym: "muscle of heart" EXACT [FMA:9462] xref: AAO:0010410 xref: BSA:0000089 xref: BTO:0000901 xref: CALOHA:TS-0440 xref: EFO:0000819 xref: EHDAA2:0004150 xref: EMAPA:32688 xref: EV:0100022 xref: FMA:9462 xref: GAID:173 xref: galen:Myocardium xref: MA:0000164 xref: MAT:0000453 xref: MESH:D009206 xref: NCIT:C12371 xref: RETIRED_EHDAA2:0001220 xref: SCTID:362012001 xref: TAO:0001319 xref: UMLS:C0027061 {source="ncithesaurus:Myocardium"} xref: VHOG:0000083 xref: Wikipedia:Myocardium xref: XAO:0000065 xref: ZFA:0001319 is_a: UBERON:0005983 ! heart layer is_a: UBERON:0018260 ! layer of muscle tissue intersection_of: UBERON:0005983 ! heart layer intersection_of: RO:0002473 UBERON:0001133 ! composed primarily of cardiac muscle tissue relationship: BFO:0000050 UBERON:0000383 ! part of musculature of body relationship: BFO:0000051 UBERON:0002350 ! has part conducting system of heart relationship: RO:0002473 UBERON:0001133 ! composed primarily of cardiac muscle tissue property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/6/6e/Glanzstreifen.jpg" xsd:anyURI [Term] id: UBERON:0002350 name: conducting system of heart namespace: uberon def: "The cardiac conduction system consists of specialized cardiomyocytes that regulate the frequency of heart beat[GO]." [GO:0003161] synonym: "cardiac conducting system" EXACT [VHOG:0001271] synonym: "cardiac conduction system" EXACT [] synonym: "cardiac impulse conducting system" EXACT [GO:0003161] synonym: "cardionector" EXACT [] synonym: "heart conduction system" EXACT [GO:0003161] synonym: "impulse conducting system" EXACT [MA:0000094] xref: EFO:0003909 xref: EHDAA2:0004185 xref: EMAPA:35428 xref: EV:0100025 xref: FMA:9476 xref: MA:0000094 xref: MESH:D006329 xref: SCTID:281489000 xref: TAO:0005063 xref: VHOG:0001271 xref: ZFA:0005063 is_a: UBERON:0004493 ! cardiac muscle tissue of myocardium is_a: UBERON:0010131 {source="FMA"} ! conducting tissue of heart relationship: BFO:0000051 CL:0002068 {source="FMA"} ! has part Purkinje myocyte relationship: BFO:0000051 CL:0002073 {source="FMA"} ! has part transitional myocyte relationship: BFO:0000051 CL:0002074 {source="FMA"} ! has part myocardial endocrine cell relationship: BFO:0000051 CL:1000409 {source="FMA"} ! has part myocyte of sinoatrial node relationship: BFO:0000051 CL:1000410 {source="FMA"} ! has part myocyte of atrioventricular node relationship: RO:0002433 UBERON:0000948 ! contributes to morphology of heart [Term] id: UBERON:0002351 name: sinoatrial node namespace: uberon def: "The part of the cardiac conduction system that controls the timing of heart muscle contraction. It relays electrical signals to the AV node[GO]. Subdivision of conducting system of heart at the junction of the right atrium and the superior vena cava, around the sinoatrial nodal branch of right coronary artery and is continuous with the internodal tract[FMA]." [GO:0003163, Wikipedia:Sinoatrial_node] synonym: "cardiac pacemaker" EXACT [FMA:9477] synonym: "Koch's node" EXACT [FMA:9477] synonym: "node of Keith-Flack" EXACT [FMA:9477] synonym: "SA nodal muscle tissue" EXACT [FMA:9477] synonym: "SA node" EXACT [FMA:9477] synonym: "sinoatrial node" EXACT [FMA:9477] synonym: "sinu-atrial node" EXACT [FMA:9477] synonym: "sinuatrial nodal muscle tissue" EXACT [FMA:9477] synonym: "sinuatrial node" EXACT [FMA:9477] synonym: "sinus node" EXACT [FMA:9477] synonym: "sinus node of Keith and Flack" EXACT [FMA:9477] xref: BTO:0004358 xref: EHDAA2:0004184 xref: EMAPA:35772 xref: FMA:9477 xref: GAID:561 xref: MA:0000097 xref: MESH:D012849 xref: NCIT:C33555 xref: SCTID:277687007 xref: TAO:0005069 xref: UMLS:C0037189 {source="ncithesaurus:Sinoatrial_Node"} xref: Wikipedia:Sinoatrial_node xref: ZFA:0005069 is_a: UBERON:0003379 ! cardiac muscle of right atrium is_a: UBERON:0010131 {source="cjm"} ! conducting tissue of heart relationship: BFO:0000050 UBERON:0002350 {source="ZFA"} ! part of conducting system of heart relationship: RO:0002215 GO:0002027 ! capable of regulation of heart rate relationship: RO:0002216 GO:0060048 ! capable of part of cardiac muscle contraction relationship: RO:0002433 UBERON:0002350 ! contributes to morphology of conducting system of heart property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/d/d2/Sinoatrial_node_low_mag.jpg" xsd:anyURI property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/d/de/Sinoatrial_node_2_low_mag.jpg" xsd:anyURI [Term] id: UBERON:0002352 name: atrioventricular node namespace: uberon def: "An area of conducting tissue between the atria and the ventricles of the heart that conducts the normal electrical impulse from the atria to the ventricles." [UBERON:cjm, Wikipedia:Atrioventricular_node] synonym: "Aschoff-Tawara node" EXACT [FMA:9478] synonym: "atrioventricular nodal muscle tissue" EXACT [FMA:9478] synonym: "AV nodal muscle tissue" EXACT [FMA:9478] synonym: "AV node" EXACT [FMA:9478, MA:0000095] synonym: "node of Tawara" EXACT [FMA:9478] xref: BTO:0005689 xref: EFO:0000276 xref: EHDAA2:0004183 xref: EMAPA:35153 xref: FMA:9478 xref: GAID:558 xref: MA:0000095 xref: MAT:0000498 xref: MESH:D001283 xref: NCIT:C32161 xref: SCTID:277688002 xref: TAO:0005070 xref: UMLS:C0004247 {source="ncithesaurus:Atrioventricular_Node"} xref: VHOG:0001474 xref: Wikipedia:Atrioventricular_node xref: ZFA:0005070 is_a: UBERON:0004491 ! cardiac muscle tissue of interatrial septum is_a: UBERON:0004493 ! cardiac muscle tissue of myocardium is_a: UBERON:0010131 {source="cjm"} ! conducting tissue of heart relationship: BFO:0000050 RO:0002577 ! part of system relationship: BFO:0000050 UBERON:0002350 ! part of conducting system of heart relationship: RO:0002170 UBERON:0002085 ! connected to interatrial septum relationship: RO:0002170 UBERON:0005979 ! connected to crista terminalis relationship: RO:0002433 UBERON:0002350 ! contributes to morphology of conducting system of heart property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/5/50/ConductionsystemoftheheartwithouttheHeart.png" xsd:anyURI property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/9/92/Gray501.png" xsd:anyURI [Term] id: UBERON:0002354 name: cardiac Purkinje fiber namespace: uberon def: "The cardiac Purkinje fiber is part of the cardiac conduction system that receives signals from the bundle of His and innervates the ventricular cardiac muscle." [GO:0003165] synonym: "cardiac Purkinje fiber" EXACT [BTO:0001735, GO:0003165] synonym: "Purkinje fiber" EXACT [FMA:9492, MA:0000096] synonym: "subendocardial branch" EXACT [Wikipedia:Purkinje_fiber] xref: BTO:0001735 xref: EMAPA:35718 xref: FMA:9492 xref: GAID:560 xref: MA:0000096 xref: MESH:D011690 xref: NCIT:C33430 xref: UMLS:C0034144 {source="ncithesaurus:Purkinje_Fiber"} xref: Wikipedia:Purkinje_fiber is_a: UBERON:0010131 {source="FMA"} ! conducting tissue of heart is_a: UBERON:0018649 ! cardiac muscle tissue of ventricle relationship: BFO:0000050 UBERON:8000009 {source="https://github.com/obophenotype/uberon/issues/1785", source="https://orcid.org/0000-0001-5208-3432", source="https://orcid.org/0000-0002-9791-0064"} ! part of Purkinje fiber network relationship: BFO:0000051 CL:0002068 {source="FMA"} ! has part Purkinje myocyte relationship: RO:0002433 UBERON:0002350 ! contributes to morphology of conducting system of heart property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/9/96/Gray498.png" xsd:anyURI [Term] id: UBERON:0002355 name: pelvic region of trunk namespace: uberon def: "The lower segment of the trunk, inferioposterior to the abdomen proper, in the transition area between the trunk and the lower limbs." [http://orcid.org/0000-0002-6601-2165, https://github.com/obophenotype/uberon/issues/720, Wikipedia:Pelvis] synonym: "lesser pelvis" EXACT [FMA:9578] synonym: "pelvic region" EXACT [] synonym: "pelvis" EXACT [FMA:9578, MA:0000030] synonym: "pelvis region" EXACT [] synonym: "true pelvis" EXACT [FMA:9578] xref: BTO:0001006 xref: CALOHA:TS-2227 xref: EFO:0002805 xref: EMAPA:35931 xref: EV:0100012 xref: FMA:9578 xref: GAID:87 xref: galen:Pelvis xref: MA:0000030 xref: MESH:D010388 xref: NCIT:C12767 xref: SCTID:229765004 xref: UMLS:C0030797 {source="ncithesaurus:Pelvis"} xref: Wikipedia:Pelvis is_a: UBERON:0000475 ! organism subdivision relationship: BFO:0000050 UBERON:0002417 ! part of abdominal segment of trunk relationship: BFO:0000051 UBERON:0007832 ! has part pelvic girdle skeleton [Term] id: UBERON:0002357 name: serous pericardium namespace: uberon def: "Serous membrane which is divided into parietal and visceral serous pericardium." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Serous_pericardium] synonym: "serous portion of pericardium" EXACT [FMA:9582] xref: EMAPA:19030 xref: FMA:9582 xref: MA:0002739 xref: SCTID:243954002 xref: Wikipedia:Serous_pericardium is_a: UBERON:0000042 ! serous membrane relationship: BFO:0000050 RO:0002577 ! part of system relationship: BFO:0000050 UBERON:0002406 {source="FMA"} ! part of pericardial sac relationship: BFO:0000051 UBERON:0002408 ! has part parietal serous pericardium relationship: BFO:0000051 UBERON:0002425 ! has part visceral serous pericardium relationship: RO:0002371 UBERON:0002359 {source="FMA"} ! attached to fibrous pericardium [Term] id: UBERON:0002358 name: peritoneum namespace: uberon def: "A serous membrane that lines the peritoneal cavity[VHOG,modified]." [VHOG:0001257] xref: AAO:0010814 xref: BTO:0001472 xref: CALOHA:TS-2072 xref: EV:0100087 xref: FMA:9584 xref: GAID:18 xref: galen:Peritoneum xref: MA:0000449 xref: MESH:D010537 xref: NCIT:C12770 xref: TAO:0005120 xref: UMLS:C0031153 {source="ncithesaurus:Peritoneum"} xref: VHOG:0001257 xref: Wikipedia:Peritoneum xref: XAO:0000139 xref: ZFA:0005120 is_a: UBERON:0000042 ! serous membrane intersection_of: UBERON:0000042 ! serous membrane intersection_of: BFO:0000050 UBERON:0035820 ! part of peritoneal sac relationship: BFO:0000050 UBERON:0003697 {source="MP"} ! part of abdominal wall relationship: BFO:0000050 UBERON:0035820 ! part of peritoneal sac property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray1040.png" xsd:anyURI [Term] id: UBERON:0002359 name: fibrous pericardium namespace: uberon def: "Membrane organ which is attached to the pericardial sac proper and the central tendon of diaphragm and is continuous with the pretracheal fascia.[FMA]." [FMA:9586] synonym: "fibrous portion of pericardium" EXACT [] xref: EMAPA:19029 xref: FMA:9586 xref: MA:0002738 xref: SCTID:243953008 xref: Wikipedia:Fibrous_pericardium is_a: UBERON:0000094 {source="FMA"} ! membrane organ is_a: UBERON:0005181 ! thoracic segment organ relationship: BFO:0000050 UBERON:0002407 {source="FMA"} ! part of pericardium relationship: RO:0002150 UBERON:0002408 ! continuous with parietal serous pericardium relationship: RO:0002473 UBERON:0006815 {source="WP"} ! composed primarily of areolar connective tissue [Term] id: UBERON:0002365 name: exocrine gland namespace: uberon def: "A gland that secretes products (excluding hormones and other chemical messengers) into ducts (duct glands) which lead directly into the external environment[WP]. Typical exocrine glands include sweat glands, salivary glands, mammary glands, stomach, liver, pancreas." [Wikipedia:Exocrine_gland] synonym: "ducted gland" EXACT [AEO:0000097] xref: AEO:0000097 xref: BTO:0000765 xref: CALOHA:TS-2012 xref: EHDAA2:0003097 xref: EMAPA:35327 xref: FMA:9596 xref: GAID:34 xref: MA:0002564 xref: MESH:D005088 xref: NCIT:C12712 xref: SCTID:115976003 xref: UMLS:C0015282 {source="ncithesaurus:Exocrine_Gland"} xref: Wikipedia:Exocrine_gland is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0002530 ! gland intersection_of: UBERON:0002530 ! gland intersection_of: BFO:0000050 UBERON:0002330 ! part of exocrine system relationship: BFO:0000050 UBERON:0002330 ! part of exocrine system relationship: BFO:0000051 UBERON:0000058 ! has part duct [Term] id: UBERON:0002368 name: endocrine gland namespace: uberon def: "Endocrine glands are glands of the endocrine system that secrete their products directly into the circulatory system rather than through a duct.[WP, modified]." [Wikipedia:Endocrine_gland] synonym: "ductless gland" EXACT [AEO:0000098] synonym: "glandula endocrina" EXACT [] xref: AEO:0000098 xref: BTO:0001488 xref: CALOHA:TS-1300 xref: EHDAA2:0003098 xref: EMAPA:35999 xref: FMA:9602 xref: GAID:335 xref: MA:0002563 xref: MESH:D004702 xref: NCIT:C12704 xref: SCTID:40818001 xref: UMLS:C0014133 {source="ncithesaurus:Endocrine_Gland"} xref: Wikipedia:Endocrine_gland is_a: UBERON:0002530 ! gland intersection_of: UBERON:0002530 ! gland intersection_of: BFO:0000050 UBERON:0000949 ! part of endocrine system relationship: BFO:0000050 UBERON:0000949 ! part of endocrine system relationship: RO:0002215 GO:0046879 ! capable of hormone secretion property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/d/da/Illu_endocrine_system.png" xsd:anyURI [Term] id: UBERON:0002371 name: bone marrow namespace: uberon def: "The soft tissue that fills the cavities of bones." [MGI:cwg, MP:0002397] xref: AAO:0011007 xref: BTO:0000141 xref: BTO:0000829 xref: CALOHA:TS-0087 xref: EFO:0000868 xref: EMAPA:32760 xref: EV:0100046 xref: FMA:9608 xref: GAID:1287 xref: galen:BoneMarrow xref: MA:0000134 xref: MAT:0000084 xref: MESH:D001853 xref: MIAA:0000084 xref: NCIT:C12431 xref: SCTID:421320006 xref: UMLS:C0005953 {source="ncithesaurus:Bone_Marrow"} xref: VHOG:0001218 xref: Wikipedia:Bone_marrow xref: XAO:0000123 is_a: UBERON:0000479 ! tissue is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0000479 ! tissue intersection_of: BFO:0000050 UBERON:0001474 ! part of bone element intersection_of: BFO:0000051 UBERON:0012429 ! has part hematopoietic tissue relationship: BFO:0000050 UBERON:0001474 ! part of bone element relationship: BFO:0000050 UBERON:0002390 {source="FMA", source="MA"} ! part of hematopoietic system relationship: BFO:0000050 UBERON:0002405 ! part of immune system relationship: BFO:0000051 CL:0002092 ! has part bone marrow cell relationship: BFO:0000051 UBERON:0012429 ! has part hematopoietic tissue property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/7/74/Gray72-en.svg" xsd:anyURI [Term] id: UBERON:0002376 name: cranial muscle namespace: uberon def: "Any skeletal muscle that is part of the head region." [http://orcid.org/0000-0002-6601-2165] synonym: "cephalic muscle" EXACT [ZFA:0001652] synonym: "cephalic musculature" EXACT [] synonym: "head muscle" EXACT [MA:0000578] synonym: "head muscle organ" EXACT [OBOL:automatic] synonym: "muscle of head" EXACT [FMA:9616] synonym: "muscle organ of adult head" EXACT [OBOL:automatic] synonym: "muscle organ of head" EXACT [OBOL:automatic] synonym: "musculus caput" EXACT [] xref: AAO:0000107 xref: BTO:0000021 xref: EFO:0003524 xref: EHDAA2:0000322 xref: EMAPA:18172 xref: FMA:9616 xref: MA:0000578 xref: SCTID:244718003 xref: ZFA:0001652 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0010959 ! craniocervical muscle intersection_of: UBERON:0014892 ! skeletal muscle organ, vertebrate intersection_of: BFO:0000050 UBERON:0000033 ! part of head intersection_of: RO:0002371 UBERON:0003129 ! attached to skull relationship: BFO:0000050 UBERON:0004461 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! part of skeletal musculature of head relationship: RO:0002202 UBERON:0006904 {source="EHDAA2-abduced"} ! develops from head mesenchyme from mesoderm relationship: RO:0002254 UBERON:0002342 {gci_filler="NCBITaxon:7742", gci_relation="BFO:0000050", source="https://github.com/obophenotype/uberon/wiki/The-neural-crest"} ! has developmental contribution from neural crest relationship: RO:0002371 UBERON:0003129 ! attached to skull [Term] id: UBERON:0002377 name: muscle of neck namespace: uberon def: "Any muscle that is part of the cervical (neck) region." [http://orcid.org/0000-0002-6601-2165] synonym: "muscle organ of neck" EXACT [OBOL:automatic] synonym: "muscle organ of neck (volume)" EXACT [OBOL:automatic] synonym: "neck (volume) muscle organ" EXACT [OBOL:automatic] synonym: "neck muscle" EXACT [] synonym: "neck muscle organ" EXACT [OBOL:automatic] xref: EMAPA:36050 xref: FMA:9617 xref: GAID:149 xref: MA:0000587 xref: MESH:D009334 xref: NCIT:C33163 xref: UMLS:C0027532 {source="ncithesaurus:Neck_Muscle"} is_a: UBERON:0010959 ! craniocervical muscle intersection_of: UBERON:0014892 ! skeletal muscle organ, vertebrate intersection_of: BFO:0000050 UBERON:0000974 ! part of neck relationship: BFO:0000050 UBERON:0004465 {source="prolog"} ! part of musculature of neck [Term] id: UBERON:0002378 name: muscle of abdomen namespace: uberon def: "Muscle (organ) which is a part of the abdomen. Examples: external oblique, rectus abdominis." [Wikipedia:Abdominal_muscle] synonym: "abdomen muscle" EXACT [] synonym: "abdomen muscle organ" EXACT [OBOL:automatic] synonym: "abdominal muscle" EXACT [] synonym: "abdominal wall muscle" EXACT [] synonym: "muscle organ of abdomen" EXACT [OBOL:automatic] xref: BTO:0001261 xref: EMAPA:35103 xref: FMA:9620 xref: GAID:89 xref: MA:0000520 xref: MESH:D000009 xref: NCIT:C32040 xref: SCTID:361352008 xref: UMLS:C0000739 {source="ncithesaurus:Abdominal_Muscle"} xref: Wikipedia:Abdominal_muscle is_a: UBERON:0003833 ! abdominal segment muscle is_a: UBERON:0005172 ! abdomen element intersection_of: UBERON:0014892 ! skeletal muscle organ, vertebrate intersection_of: BFO:0000050 UBERON:0000916 ! part of abdomen relationship: BFO:0000050 UBERON:0002343 {source="prolog"} ! part of abdomen musculature relationship: BFO:0000050 UBERON:0003697 ! part of abdominal wall [Term] id: UBERON:0002384 name: connective tissue namespace: uberon def: "Tissue with cells that deposit non-polarized extracellular matrix including connective tissue fibers and ground substance." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, https://github.com/obophenotype/uberon/issues/23, PSPUB:0000170, VSAO:0000017] synonym: "portion of connective tissue" EXACT [FMA:9640] synonym: "textus connectivus" EXACT [] xref: AAO:0000098 xref: BTO:0000421 xref: CALOHA:TS-2009 xref: EFO:0000952 xref: EMAPA:35251 xref: FMA:9640 xref: GAID:100 xref: galen:ConnectiveTissue xref: MA:0000011 xref: MAT:0000301 xref: MESH:D003238 xref: MIAA:0000301 xref: NCIT:C12374 xref: SCTID:361919005 xref: TAO:0001641 xref: UMLS:C0009780 {source="ncithesaurus:Connective_Tissue"} xref: VSAO:0000017 xref: XAO:0001017 xref: ZFA:0001632 is_a: UBERON:0000479 ! tissue relationship: RO:0002160 NCBITaxon:6072 ! only in taxon Eumetazoa property_value: x_1.1:contributor https://github.com/cmungall property_value: x_1.1:contributor https://github.com/wdahdul [Term] id: UBERON:0002385 name: muscle tissue namespace: uberon def: "Muscle tissue is a contractile tissue made up of actin and myosin fibers[GO]." [GO:0060537, https://sourceforge.net/tracker/index.php?func=detail&aid=2801266&group_id=36855&atid=440764, Wikipedia:Muscle_tissue] synonym: "portion of muscle tissue" EXACT [FMA:9641] synonym: "textus muscularis" EXACT [] xref: AAO:0000306 xref: AEO:0000122 xref: CALOHA:TS-0642 xref: EHDAA2:0003122 xref: EMAPA:32715 xref: FMA:9641 xref: galen:MuscleTissue xref: MA:0002437 xref: MESH:D009132 xref: NCIT:C12435 xref: SCTID:91727004 xref: UMLS:C2328219 {source="ncithesaurus:Muscle_Tissue"} xref: Wikipedia:Muscle_tissue is_a: UBERON:0000479 ! tissue is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0000479 ! tissue intersection_of: RO:0002473 CL:0000187 ! composed primarily of muscle cell disjoint_from: UBERON:0003714 ! neural tissue relationship: BFO:0000050 UBERON:0001015 ! part of musculature relationship: RO:0002160 NCBITaxon:6072 ! only in taxon Eumetazoa relationship: RO:0002215 GO:0006936 ! capable of muscle contraction relationship: RO:0002473 CL:0000187 ! composed primarily of muscle cell [Term] id: UBERON:0002390 name: hematopoietic system namespace: uberon def: "Anatomical system that is involved in the production of hematopoietic cells." [Wikipedia:Haematopoiesis] synonym: "haematological system" EXACT [] synonym: "haemopoietic system" EXACT [] synonym: "organa haemopoietica" EXACT [] xref: AAO:0011002 xref: BTO:0000570 xref: CALOHA:TS-0449 xref: EFO:0000798 xref: EMAPA:35402 xref: EV:0100045 xref: FMA:9667 xref: GAID:1008 xref: MA:0002434 xref: MAT:0000022 xref: MESH:D006413 xref: MIAA:0000022 xref: NCIT:C12909 xref: SCTID:362587009 xref: TAO:0005023 xref: UMLS:C0018957 {source="ncithesaurus:Hematopoietic_System"} xref: VHOG:0001624 xref: Wikipedia:Haematopoiesis xref: XAO:0000122 xref: ZFA:0005023 is_a: UBERON:0000467 ! anatomical system is_a: UBERON:0004120 ! mesoderm-derived structure disjoint_from: UBERON:0002405 ! immune system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:8450002 ! excretory system relationship: BFO:0000050 UBERON:0002193 {source="FMA"} ! part of hemolymphoid system relationship: RO:0002160 NCBITaxon:7711 ! only in taxon Chordata relationship: RO:0002202 UBERON:0003061 ! develops from blood island [Term] id: UBERON:0002394 name: bile duct namespace: uberon def: "Any of the ducts that form the biliary tree, carrying bile from the liver to the small intestine." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Bile_duct] xref: AAO:0011019 xref: BTO:0000122 xref: CALOHA:TS-0075 xref: EHDAA2:0000741 xref: EMAPA:35171 xref: EV:0100091 xref: FMA:9706 xref: GAID:280 xref: MA:0000354 xref: MESH:D001652 xref: NCIT:C12376 xref: SCTID:276157007 xref: TAO:0001100 xref: UMLS:C0005400 {source="ncithesaurus:Bile_Duct"} xref: VHOG:0000212 xref: Wikipedia:Bile_duct xref: XAO:0000134 xref: ZFA:0001100 is_a: UBERON:0000025 ! tube is_a: UBERON:0003928 ! digestive system duct is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: UBERON:0000058 ! duct intersection_of: BFO:0000050 UBERON:0001173 ! part of biliary tree relationship: BFO:0000050 UBERON:0001173 {source="EMAPA", source="MA"} ! part of biliary tree relationship: channel_for UBERON:0001970 ! bile relationship: RO:0002202 UBERON:0008835 {source="XAO"} ! develops from hepatic diverticulum relationship: RO:0002433 UBERON:0001173 ! contributes to morphology of biliary tree property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/5/5d/Digestive_system_showing_bile_duct.png" xsd:anyURI [Term] id: UBERON:0002396 name: vomer namespace: uberon def: "The triangular flat bone of the nasal septum." [ISBN:0-683-40008-8, MP:0000098] synonym: "vomer bone" EXACT [] xref: AAO:0000633 xref: FMA:9710 xref: MA:0001496 xref: NCIT:C33888 xref: SCTID:272678009 xref: TAO:0000308 xref: UMLS:C0242403 {source="ncithesaurus:Vomer"} xref: Wikipedia:Vomer xref: ZFA:0000308 is_a: UBERON:0008001 {source="FMA"} ! irregular bone is_a: UBERON:0011597 ! bone of upper jaw is_a: UBERON:0012071 ! palate bone relationship: BFO:0000050 UBERON:0011085 ! part of palatoquadrate arch relationship: RO:0002170 UBERON:0001677 {gci_filler="NCBITaxon:9606", gci_relation="BFO:0000050", source="FMA"} ! connected to sphenoid bone relationship: RO:0002170 UBERON:0001679 {gci_filler="NCBITaxon:9606", gci_relation="BFO:0000050", source="FMA"} ! connected to ethmoid bone relationship: RO:0002433 UBERON:0011156 ! contributes to morphology of facial skeleton property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/7/77/Illu_facial_bones.jpg" xsd:anyURI [Term] id: UBERON:0002400 name: parietal pleura namespace: uberon def: "The outer serous membrane of the pulmonary pleural." [UBERON:cjm, Wikipedia:Pulmonary_pleurae] xref: EMAPA:16776 xref: FMA:9733 xref: MA:0002488 xref: NCIT:C33273 xref: SCTID:361998003 xref: UMLS:C0225777 {source="ncithesaurus:Parietal_Pleura"} xref: VHOG:0001495 xref: Wikipedia:Parietal_pleura is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure is_a: UBERON:0004923 ! organ component layer intersection_of: UBERON:0004923 ! organ component layer intersection_of: BFO:0000050 UBERON:0000977 ! part of pleura intersection_of: RO:0002220 UBERON:0002224 ! adjacent to thoracic cavity relationship: BFO:0000050 UBERON:0000977 ! part of pleura relationship: RO:0002005 UBERON:0003727 ! innervated_by intercostal nerve relationship: RO:0002220 UBERON:0002224 ! adjacent to thoracic cavity relationship: RO:0002433 UBERON:0000977 ! contributes to morphology of pleura [Term] id: UBERON:0002401 name: visceral pleura namespace: uberon def: "The inner serous membrane of the pulmonary pleural. The visceral pleura lines the lungs." [UBERON:cjm, Wikipedia:Pulmonary_pleurae] synonym: "pleura visceralis (pulmonalis)" EXACT [] synonym: "pulmonary visceral pleura" EXACT [] xref: EHDAA2:0002205 xref: EMAPA:16777 xref: FMA:9734 xref: MA:0002489 xref: NCIT:C33881 xref: SCTID:361997008 xref: UMLS:C0225776 {source="ncithesaurus:Visceral_Pleura"} xref: VHOG:0001496 is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure is_a: UBERON:0022350 ! visceral serous membrane intersection_of: UBERON:0004923 ! organ component layer intersection_of: BFO:0000050 UBERON:0000977 ! part of pleura intersection_of: RO:0002220 UBERON:0002048 ! adjacent to lung relationship: BFO:0000050 RO:0002577 ! part of system relationship: BFO:0000050 UBERON:0000977 ! part of pleura relationship: BFO:0000050 UBERON:0002048 {source="FMA"} ! part of lung relationship: RO:0002220 UBERON:0002048 ! adjacent to lung relationship: RO:0002371 UBERON:0008946 ! attached to lung parenchyma relationship: RO:0002433 UBERON:0000977 ! contributes to morphology of pleura [Term] id: UBERON:0002402 name: pleural cavity namespace: uberon def: "The fluid-filled cavity that lies between the visceral and parietal pleurae." [https://github.com/obophenotype/uberon/issues/86, Wikipedia:Pleural_cavity] xref: BTO:0004422 xref: EHDAA2:0001475 xref: EMAPA:16773 xref: EMAPA:16774 xref: FMA:9740 xref: GAID:95 xref: MA:0000055 xref: MESH:D035422 xref: NCIT:C12840 xref: SCTID:361999006 xref: UMLS:C0178802 {source="ncithesaurus:Pleural_Cavity"} xref: VHOG:0000581 xref: Wikipedia:Pleural_cavity is_a: UBERON:0035809 ! serous cavity intersection_of: UBERON:0002553 ! anatomical cavity intersection_of: RO:0002572 UBERON:0009778 ! luminal space of pleural sac relationship: RO:0002202 UBERON:0003887 {source="Wikipedia"} ! develops from intraembryonic coelom relationship: RO:0002220 UBERON:0002400 ! adjacent to parietal pleura relationship: RO:0002220 UBERON:0002401 ! adjacent to visceral pleura relationship: RO:0002572 UBERON:0009778 ! luminal space of pleural sac property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/a/ab/Gray965.png" xsd:anyURI [Term] id: UBERON:0002405 name: immune system namespace: uberon def: "Anatomical system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymphoid tissue, lymphocytes including the B cells and T cells, and antibodies." [Wikipedia:Immune_system] xref: AAO:0011003 xref: BILA:0000104 xref: BTO:0005810 xref: FMA:9825 xref: GAID:328 xref: MA:0002711 xref: MESH:D007107 xref: NCIT:C12735 xref: SCTID:362590003 xref: TAO:0001159 xref: UMLS:C0020962 {source="ncithesaurus:Immune_System"} xref: VHOG:0001247 xref: Wikipedia:Immune_system xref: XAO:0003152 xref: ZFA:0001159 is_a: UBERON:0015203 ! non-connected functional system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:8450002 ! excretory system relationship: protects UBERON:0000468 ! multicellular organism relationship: RO:0002215 GO:0002376 ! capable of immune system process relationship: RO:0002492 UBERON:0000066 ! existence ends during fully formed stage [Term] id: UBERON:0002406 name: pericardial sac namespace: uberon def: "A double-walled sac containing the heart and the roots of the great vessels." [https://github.com/obophenotype/uberon/issues/86, Wikipedia:Pericardium] xref: FMA:9868 xref: RETIRED_EHDAA2:0001443 xref: SCTID:361326002 xref: TAO:0000054 is_a: UBERON:0005181 ! thoracic segment organ is_a: UBERON:0005906 ! serous sac intersection_of: UBERON:0005906 ! serous sac intersection_of: BFO:0000051 UBERON:0001074 ! has part pericardial cavity intersection_of: BFO:0000051 UBERON:0002357 ! has part serous pericardium relationship: BFO:0000050 UBERON:0002407 ! part of pericardium relationship: BFO:0000051 UBERON:0001074 ! has part pericardial cavity relationship: BFO:0000051 UBERON:0002357 ! has part serous pericardium relationship: RO:0002219 UBERON:0002359 {source="FMA"} ! surrounded by fibrous pericardium property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/7/7e/Gray489.png" xsd:anyURI [Term] id: UBERON:0002407 name: pericardium namespace: uberon def: "The combination of pericardial sac (a double-walled sac containing the heart and the roots of the great vessels) plus fibrous pericardium." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Pericardium] xref: AAO:0010817 xref: BSA:0000090 xref: BTO:0000717 xref: CALOHA:TS-0761 xref: EFO:0000820 xref: EHDAA:5376 xref: EMAPA:16133 xref: EV:0100023 xref: FMA:9869 xref: GAID:569 xref: galen:Pericardium xref: MA:0000099 xref: MAT:0000454 xref: MESH:D010496 xref: NCIT:C13005 xref: RETIRED_EHDAA2:0001443 xref: SCTID:181295003 xref: TAO:0000054 xref: UMLS:C0031050 {source="ncithesaurus:Pericardium"} xref: VHOG:0001280 xref: Wikipedia:Pericardium xref: XAO:0004182 xref: ZFA:0000054 is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000481 ! multi-tissue structure relationship: BFO:0000050 NCBITaxon:6072 ! part of Eumetazoa relationship: BFO:0000050 UBERON:0015410 {source="MA"} ! part of heart plus pericardium relationship: BFO:0000051 UBERON:0002359 ! has part fibrous pericardium relationship: BFO:0000051 UBERON:0002406 ! has part pericardial sac relationship: RO:0002221 UBERON:0002349 ! surrounds myocardium property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/7/7e/Gray489.png" xsd:anyURI [Term] id: UBERON:0002408 name: parietal serous pericardium namespace: uberon def: "Parietal serous membrane which is part of the pericardium and forms the outer layer of the pericardial sac." [http://orcid.org/0000-0002-6601-2165] synonym: "lamina parietalis (pericardii serosum)" EXACT [] synonym: "parietal layer of serous pericardium" EXACT [] synonym: "parietal pericardium" EXACT [VHOG:0000537] xref: EHDAA:3422 xref: EHDAA:5378 xref: EMAPA:19031 xref: FMA:9870 xref: MA:0000483 xref: NCIT:C94500 xref: SCTID:243956000 xref: UMLS:C0225969 {source="ncithesaurus:Parietal_Pericardium"} xref: VHOG:0000537 xref: Wikipedia:Parietal_pericardium is_a: UBERON:0022351 ! parietal serous membrane intersection_of: UBERON:0022351 ! parietal serous membrane intersection_of: BFO:0000050 UBERON:0002357 ! part of serous pericardium relationship: BFO:0000050 UBERON:0002357 ! part of serous pericardium relationship: RO:0002371 UBERON:0006670 {gci_filler="NCBITaxon:40674", gci_relation="BFO:0000050", source="FMA"} ! attached to central tendon of diaphragm property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/7/7e/Gray489.png" xsd:anyURI [Term] id: UBERON:0002409 name: pericardial fluid namespace: uberon def: "Transudate contained in the pericardial cavity.[FMA]." [FMA:9887, Wikipedia:Pericardial_fluid] xref: BTO:0001016 xref: FMA:9887 xref: MA:0002530 xref: Wikipedia:Pericardial_fluid is_a: UBERON:0007794 {source="FMA"} ! secretion of serous gland is_a: UBERON:0036217 ! coelomic fluid intersection_of: UBERON:0000463 ! organism substance intersection_of: RO:0003001 UBERON:0002425 ! produced by visceral serous pericardium relationship: RO:0001025 UBERON:0001074 ! located in pericardial cavity relationship: RO:0003001 UBERON:0002425 ! produced by visceral serous pericardium [Term] id: UBERON:0002410 name: autonomic nervous system namespace: uberon def: "The autonomic nervous system is composed of neurons that are not under conscious control, and is comprised of two antagonistic components, the sympathetic and parasympathetic nervous systems. The autonomic nervous system regulates key functions including the activity of the cardiac (heart) muscle, smooth muscles (e.g. of the gut), and glands[GO]." [GO:0048483] synonym: "autonomic division of peripheral nervous system" EXACT [FMA:65553] synonym: "autonomic part of peripheral nervous system" EXACT [FMA:65553] synonym: "divisio autonomica systematis nervosi peripherici" EXACT [FMA:TA] synonym: "pars autonomica systematis nervosi peripherici" EXACT [FMA:TA] synonym: "peripheral autonomic nervous system" EXACT [FMA:65553] synonym: "visceral nervous system" EXACT [] xref: AAO:0000033 xref: BIRNLEX:1123 xref: BTO:0002507 xref: CALOHA:TS-2001 xref: EHDA:10095 xref: EHDAA2:0000158 xref: EHDAA:3767 xref: EMAPA:16984 xref: FMA:65553 xref: GAID:706 xref: MA:0000219 xref: MESH:D001341 xref: NCIT:C12673 xref: neuronames:2054 xref: SCTID:362481007 xref: TAO:0001574 xref: UMLS:C0004388 {source="ncithesaurus:Autonomic_Nervous_System", source="BIRNLEX:1123"} xref: UMLS:C1305381 {source="BIRNLEX:1123"} xref: VHOG:0000396 xref: Wikipedia:Autonomic_nervous_system xref: ZFA:0001574 is_a: UBERON:0011216 {source="cjm"} ! organ system subdivision relationship: BFO:0000050 UBERON:0000010 {source="EMAPA", source="MA", source="NIFSTD", source="ZFA-modified-from-isa"} ! part of peripheral nervous system relationship: RO:0002160 NCBITaxon:7742 ! only in taxon Vertebrata relationship: RO:0002433 UBERON:0001016 ! contributes to morphology of nervous system property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/f/f7/Gray839.png" xsd:anyURI [Term] id: UBERON:0002411 name: clitoris namespace: uberon def: "The small, erectile body located at the anterior end of the vulva." [ISBN:0-683-40008-8, MP:0003127] xref: BTO:0002020 xref: EHDAA2:0000255 xref: EHDAA:9360 xref: EMAPA:30819 xref: FMA:9909 xref: GAID:385 xref: galen:Clitoris xref: MA:0000382 xref: MESH:D002987 xref: NCIT:C12308 xref: SCTID:181442003 xref: UMLS:C0008984 {source="ncithesaurus:Clitoris"} xref: VHOG:0000700 xref: Wikipedia:Clitoris is_a: UBERON:0000062 {source="Wikipedia"} ! organ is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005156 ! reproductive structure relationship: BFO:0000050 UBERON:0000997 {source="MA"} ! part of mammalian vulva relationship: RO:0002160 NCBITaxon:40674 {source="Wikipedia"} ! only in taxon Mammalia relationship: RO:0002202 UBERON:0005876 {source="EHDAA2", source="Wikipedia"} ! develops from undifferentiated genital tubercle relationship: RO:0002433 UBERON:0005056 ! contributes to morphology of external female genitalia property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/c/cf/Clitoris_anatomy_labeled-en.svg" xsd:anyURI [Term] id: UBERON:0002412 name: vertebra namespace: uberon def: "The ossified form of a vertebral element, a skeletal element that forms around the notochord and is part of the vertebral column." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, http://orcid.org/0000-0002-6601-2165, VSAO:0000184] synonym: "vertebra bone" EXACT [] xref: AAO:0000691 xref: CALOHA:TS-2352 xref: EFO:0001371 xref: EMAPA:32740 xref: FMA:9914 xref: galen:Vertebra xref: MA:0000309 xref: NCIT:C12933 xref: SCTID:181817002 xref: TAO:0001189 xref: UMLS:C0549207 {source="ncithesaurus:Vertebra"} xref: Wikipedia:Vertebra xref: XAO:0004019 xref: ZFA:0001189 is_a: UBERON:0002513 ! endochondral bone is_a: UBERON:0008001 {source="FMA"} ! irregular bone is_a: UBERON:0010913 ! vertebral element intersection_of: UBERON:0010913 ! vertebral element intersection_of: RO:0002473 UBERON:0002481 ! composed primarily of bone tissue relationship: BFO:0000050 UBERON:0001130 ! part of vertebral column relationship: RO:0002202 UBERON:0011094 ! develops from vertebra cartilage element [Term] id: UBERON:0002413 name: cervical vertebra namespace: uberon def: "A vertebra that is located in the cervical region of the vertebral column." [http://orcid.org/0000-0002-6601-2165] xref: EMAPA:17674 xref: FMA:9915 xref: GAID:235 xref: galen:CervicalVertebra xref: MA:0000311 xref: MESH:D002574 xref: NCIT:C12693 xref: SCTID:181820005 xref: Wikipedia:Cervical_vertebrae xref: XAO:0003076 is_a: UBERON:0003458 ! neck bone is_a: UBERON:0004247 ! bone of dorsum is_a: UBERON:0004451 ! trunk or cervical vertebra is_a: UBERON:0015007 ! cervical vertebra endochondral element intersection_of: UBERON:0015007 ! cervical vertebra endochondral element intersection_of: RO:0002473 UBERON:0002481 ! composed primarily of bone tissue relationship: RO:0002202 UBERON:0013505 ! develops from cervical vertebra cartilage element property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/f/f8/Illu_vertebral_column.jpg" xsd:anyURI [Term] id: UBERON:0002415 name: tail namespace: uberon def: "An external caudal extension of the body. In chordates, the tail is post-anal, in other animals the anus ends in the tail." [AEO:0000109, Wikipedia:Tail] synonym: "caudal subdivision" EXACT [https://orcid.org/0000-0002-6601-2165] xref: AEO:0000109 xref: BILA:0000117 xref: BTO:0001348 xref: EFO:0000963 xref: EHDAA:9198 xref: GAID:1245 xref: MAT:0000094 xref: MESH:D013623 xref: MIAA:0000094 xref: WBbt:0005741 xref: Wikipedia:Tail is_a: UBERON:0011676 ! subdivision of organism along main body axis relationship: BFO:0000050 UBERON:0000154 ! part of posterior region of body relationship: RO:0002160 NCBITaxon:33213 ! only in taxon Bilateria [Term] id: UBERON:0002416 name: integumental system namespace: uberon def: "Connected anatomical system that forms a barrier between an animal and its environment. In vertebrates, the integumental system consists of the epidermis, dermis plus associated glands and adnexa such as hair and scales. In invertebrates, the integumental system may include cuticle." [CARO:0002001, http://orcid.org/0000-0002-6601-2165, https://github.com/obophenotype/uberon/issues/29] synonym: "integumentary system" EXACT [FMA:72979] xref: AEO:0000154 xref: BILA:0000118 xref: CALOHA:TS-1299 xref: CARO:0002001 xref: EFO:0000807 xref: EHDAA2:0000836 xref: EHDAA2_RETIRED:0003154 xref: EHDAA:6520 xref: EMAPA:17524 xref: EV:0100151 xref: FMA:72979 xref: galen:Surface xref: HAO:0000421 xref: MA:0000014 xref: MAT:0000033 xref: MESH:D034582 xref: MIAA:0000033 xref: NCIT:C12907 xref: SCTID:361692004 xref: TADS:0000108 xref: UMLS:C0037267 {source="ncithesaurus:Integumentary_System"} xref: VHOG:0000403 xref: Wikipedia:Integumentary_system xref: XAO:0000176 is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000467 ! anatomical system disjoint_from: UBERON:0002423 ! hepatobiliary system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:8450002 ! excretory system relationship: BFO:0000051 UBERON:0007376 ! has part outer epithelium relationship: RO:0002007 UBERON:0000468 ! bounding layer of multicellular organism relationship: RO:0002219 UBERON:0013514 ! surrounded by space surrounding organism relationship: RO:0002492 UBERON:0000066 ! existence ends during fully formed stage property_value: x_1.1:contributor https://github.com/cmungall property_value: x_1.1:contributor https://github.com/tfhayamizu [Term] id: UBERON:0002417 name: abdominal segment of trunk namespace: uberon def: "The abdominal segment of the torso." [Wikipedia:Lumbar] xref: EMAPA:35104 xref: FMA:259211 xref: MA:0000021 xref: SCTID:362875007 xref: Wikipedia:Lumbar is_a: UBERON:0009569 {source="FMA"} ! subdivision of trunk is_a: UBERON:0011676 ! subdivision of organism along main body axis [Term] id: UBERON:0002418 name: cartilage tissue namespace: uberon def: "Skeletal tissue that is avascular, rich in glycosaminoglycans (GAGs) and typically includes chondrocytes within isolated lacunae. Cartilage tissue is deposited by chondroblasts." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, https://github.com/obophenotype/uberon/issues/37, https://sourceforge.net/p/obo/vertebrate-skeletal-anatomy-vsao-term-requests/5, PSPUB:0000170, VSAO:0000040] synonym: "cartilage tissue" EXACT [FMA:37377] synonym: "cartilaginous tissue" EXACT [] synonym: "chondrogenic tissue" EXACT [VSAO:0000040] xref: AAO:0000060 xref: AEO:0000087 xref: BTO:0000206 xref: EFO:0000949 xref: EHDAA2:0003087 xref: EMAPA:32730 xref: EV:0100141 xref: FMA:37377 xref: GAID:99 xref: galen:Cartilage xref: MA:0000104 xref: MAT:0000189 xref: MESH:D002356 xref: MIAA:0000189 xref: NCIT:C12373 xref: NCIT:C32268 xref: SCTID:309312004 xref: TAO:0001501 xref: UMLS:C0007301 {source="ncithesaurus:Cartilage"} xref: VHOG:0001207 xref: VSAO:0000040 xref: Wikipedia:Cartilage xref: XAO:0000170 xref: ZFA:0005622 is_a: UBERON:0004755 ! skeletal tissue disjoint_from: UBERON:0002481 {source="https://github.com/obophenotype/uberon/issues/117"} ! bone tissue relationship: BFO:0000051 CHEBI:18085 ! has part glycosaminoglycan relationship: BFO:0000051 CL:0000138 ! has part chondrocyte relationship: RO:0002160 NCBITaxon:33213 ! only in taxon Bilateria relationship: RO:0002433 UBERON:0001434 ! contributes to morphology of skeletal system property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/e/ee/Hypertrophic_Zone_of_Epiphyseal_Plate.jpg" xsd:anyURI property_value: x_1.1:contributor https://github.com/cmungall property_value: x_1.1:contributor https://github.com/mellybelly [Term] id: UBERON:0002419 name: skin gland namespace: uberon def: "A gland that is part of a skin of body [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:35774 xref: FMA:71878 xref: MA:0000146 xref: SCTID:110485007 is_a: UBERON:0003297 ! gland of integumental system is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0006003 ! integumentary adnexa intersection_of: UBERON:0002530 ! gland intersection_of: BFO:0000050 UBERON:0002097 ! part of skin of body relationship: BFO:0000050 UBERON:0002097 ! part of skin of body [Term] id: UBERON:0002423 name: hepatobiliary system namespace: uberon def: "The part of the digestive system that contains the liver and the biliary system." [http://orcid.org/0000-0002-6601-2165] synonym: "hepaticobiliary system" EXACT [GO:0061008] synonym: "liver and biliary system" EXACT [] xref: AAO:0011056 xref: CALOHA:TS-1308 xref: EFO:0000800 xref: EHDAA2:0000998 xref: EHDAA:2189 xref: EMAPA:16840 xref: EV:0100088 xref: MA:0000324 xref: MAT:0000024 xref: MIAA:0000024 xref: NCIT:C43612 xref: TAO:0000036 xref: UMLS:C1711359 {source="ncithesaurus:Hepatobiliary_System"} xref: VHOG:0000294 xref: Wikipedia:Hepatobiliary_system xref: XAO:0000132 xref: ZFA:0000036 is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0011216 ! organ system subdivision disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:8450002 ! excretory system relationship: BFO:0000050 UBERON:0001007 ! part of digestive system relationship: BFO:0000051 UBERON:0002107 ! has part liver relationship: BFO:0000051 UBERON:0002294 ! has part biliary system relationship: RO:0002160 NCBITaxon:7742 ! only in taxon Vertebrata relationship: RO:0002215 GO:0061007 ! capable of hepaticobiliary system process relationship: RO:0002492 UBERON:0000066 ! existence ends during fully formed stage [Term] id: UBERON:0002424 name: oral epithelium namespace: uberon def: "An epithelium that is part of the mouth and lines the oral cavity, typically stratified squamous, and may be para-, ortho- or non- keratinized. Primary barrier between oral environment and deeper tissues." [https://orcid.org/0000-0002-6601-2165] synonym: "epithelium of mucosa of mouth" EXACT [FMA:265152] synonym: "epithelium of oral mucosa" EXACT [FMA:265152] xref: AAO:0010357 xref: BTO:0001775 xref: CALOHA:TS-0715 xref: EHDAA2:0001325 xref: EHDAA:2187 xref: EMAPA:16839 xref: EMAPA:26942 xref: FMA:265152 xref: MA:0000344 xref: NCIT:C49595 xref: TAO:0000816 xref: UMLS:C1709332 {source="ncithesaurus:Oral_Cavity_Epithelium"} xref: VHOG:0000187 xref: XAO:0003201 xref: ZFA:0000816 is_a: UBERON:0003350 ! epithelium of mucosa is_a: UBERON:0003929 ! digestive tract epithelium is_a: UBERON:0006915 {gci_filler="NCBITaxon:9606", gci_relation="BFO:0000050", source="FMA"} ! stratified squamous epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: BFO:0000050 UBERON:0003729 ! part of mouth mucosa relationship: BFO:0000050 UBERON:0003729 ! part of mouth mucosa relationship: RO:0002220 UBERON:0000167 {source="AAO-modified"} ! adjacent to oral cavity [Term] id: UBERON:0002425 name: visceral serous pericardium namespace: uberon def: "Visceral serous membrane which is continuous with the parietal serous pericardium and is attached to the myocardium[FMA]." [Wikipedia:Visceral_pericardium] synonym: "serous visceral pericardium" EXACT [] synonym: "visceral lamina of serous pericardium" EXACT [] synonym: "visceral layer of serous pericardium" EXACT [] synonym: "visceral pericardium" EXACT [VHOG:0000538] xref: EMAPA:16589 xref: EMAPA:19032 xref: FMA:84882 xref: MA:0000484 xref: SCTID:243955001 xref: VHOG:0000538 xref: Wikipedia:Visceral_pericardium is_a: UBERON:0022350 ! visceral serous membrane intersection_of: UBERON:0022350 ! visceral serous membrane intersection_of: BFO:0000050 UBERON:0002357 ! part of serous pericardium relationship: BFO:0000050 UBERON:0002357 ! part of serous pericardium relationship: BFO:0000051 UBERON:0002348 {source="cjm"} ! has part epicardium relationship: RO:0002371 UBERON:0002349 {source="FMA"} ! attached to myocardium relationship: RO:0002433 UBERON:0002407 ! contributes to morphology of pericardium [Term] id: UBERON:0002443 name: choroidal blood vessel namespace: uberon def: "A blood vessel that is part of a choroid [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of choroid" EXACT [OBOL:automatic] synonym: "blood vessel of choroid coat" EXACT [OBOL:automatic] synonym: "blood vessel of choroidea" EXACT [OBOL:automatic] synonym: "blood vessel of posterior uvea" EXACT [OBOL:automatic] synonym: "choroid blood vessel" EXACT [OBOL:automatic] synonym: "choroid blood vessels" EXACT [] synonym: "choroid blood vessels set" EXACT [] synonym: "choroid coat blood vessel" EXACT [OBOL:automatic] synonym: "choroidea blood vessel" EXACT [OBOL:automatic] synonym: "posterior uvea blood vessel" EXACT [OBOL:automatic] xref: EMAPA:17828 xref: FMA:76550 xref: MA:0001237 is_a: UBERON:0003496 ! head blood vessel is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: UBERON:0001981 ! blood vessel intersection_of: BFO:0000050 UBERON:0001776 ! part of optic choroid relationship: BFO:0000050 UBERON:0001776 ! part of optic choroid [Term] id: UBERON:0002450 name: decidua namespace: uberon def: "The maternal uterine-derived portion of the placenta." [MP:0004256, PMID:11433360] synonym: "decidous membrane" EXACT [FMA:85538] xref: BTO:0001360 xref: CALOHA:TS-0193 xref: EMAPA:35269 xref: FMA:85538 xref: GAID:378 xref: MA:0001722 xref: MAT:0000290 xref: MESH:D003656 xref: MIAA:0000290 xref: NCIT:C32425 xref: SCTID:362842004 xref: UMLS:C0011106 {source="ncithesaurus:Decidua"} xref: Wikipedia:Decidua is_a: UBERON:0000478 {source="FMA"} ! extraembryonic structure relationship: BFO:0000050 UBERON:0001987 ! part of placenta relationship: RO:0002202 UBERON:0000459 ! develops from uterine wall relationship: RO:0002433 UBERON:0001987 ! contributes to morphology of placenta property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/f/fa/Gray33.png" xsd:anyURI [Term] id: UBERON:0002451 name: endometrial gland namespace: uberon def: "The mucous secreting gland associated with the mucuous membrane lining the uterus." [Wikipedia:Uterine_glands] synonym: "endometrial gland" EXACT [BTO:0003433] synonym: "endometrial mucuous gland" EXACT [] synonym: "endometrium gland" EXACT [] synonym: "uterine gland" EXACT [] xref: BTO:0003433 xref: BTO:0004518 xref: EMAPA:29919 xref: MA:0001726 xref: NCIT:C33842 xref: SCTID:361377009 xref: UMLS:C1183035 {source="ncithesaurus:Uterine_Gland"} xref: Wikipedia:Uterine_glands is_a: UBERON:0000414 {source="MP"} ! mucous gland is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005179 ! pelvic region element is_a: UBERON:0005398 ! female reproductive gland intersection_of: UBERON:0002530 ! gland intersection_of: BFO:0000050 UBERON:0001295 ! part of endometrium relationship: BFO:0000050 UBERON:0012276 ! part of endometrium glandular epithelium relationship: RO:0000086 PATO:0002299 {source="Wikipedia:Tubular_gland"} ! has quality tubular property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/2/28/Gray1169.png" xsd:anyURI [Term] id: UBERON:0002457 name: intersomitic artery namespace: uberon def: "The small branching sprouts of the dorsal aorta that grow across the medial surface of the somite, turn right angles to grow over that surface and then fuse with other sprouts and form the vertebral arteries adjacent to the neural tube; the intersomitic arteries supply the body wall and persist in the adult as the posterior intercostal, subcostal and the lumbar arteries." [MP:0010662] synonym: "intersegmental artery" EXACT [ZFA:0001061] xref: EHDAA2:0000882 xref: EHDAA:4340 xref: EMAPA:17616 xref: MA:0001985 xref: SCTID:360401001 xref: TAO:0001061 xref: VHOG:0000225 xref: XAO:0004165 xref: ZFA:0001061 is_a: UBERON:0001637 ! artery is_a: UBERON:0014907 ! intersomitic vessel [Term] id: UBERON:0002458 name: spinal artery namespace: uberon def: "Arteries that supply the spinal cord." [https://orcid.org/0000-0002-6601-2165, Wikipedia:Spinal_artery] xref: EHDAA2:0001890 xref: EHDAA:4355 xref: EMAPA:18241 xref: MA:0002043 xref: NCIT:C33587 xref: SCTID:244228006 xref: TAO:0000682 xref: UMLS:C0447043 {source="ncithesaurus:Spinal_Artery"} xref: Wikipedia:Spinal_artery xref: ZFA:0000682 is_a: UBERON:0004573 ! systemic artery intersection_of: UBERON:0001637 ! artery intersection_of: RO:0002178 UBERON:0002240 ! supplies spinal cord relationship: BFO:0000050 RO:0002577 ! part of system relationship: RO:0002178 UBERON:0002240 ! supplies spinal cord [Term] id: UBERON:0002460 name: vesical vein namespace: uberon def: "A tributary of the iliac vein that drains the urinary bladder." [UBERON:cjm, Wikipedia:Vesical_veins] synonym: "vesical veins set" EXACT [] xref: EMAPA:37205 {source="MA:th"} xref: MA:0002263 xref: SCTID:12683000 xref: Wikipedia:Vesical_veins is_a: UBERON:0001638 ! vein intersection_of: UBERON:0001638 ! vein intersection_of: RO:0002179 UBERON:0001255 ! drains urinary bladder relationship: BFO:0000050 RO:0002577 ! part of system relationship: RO:0002179 UBERON:0001255 ! drains urinary bladder relationship: RO:0002376 UBERON:0001317 ! tributary of internal iliac vein property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/b/bd/Gray585.png" xsd:anyURI [Term] id: UBERON:0002466 name: intestine secretion namespace: uberon def: "Clear to pale yellow watery secretions from the glands lining the small intestine walls. Secretion is stimulated by the mechanical pressure of partly digested food in the intestine." [Wikipedia:Succus_entericus] synonym: "intestinal secretion" EXACT [FMA:62974] synonym: "succus entericus" EXACT [Wikipedia:Succus_entericus] xref: BTO:0000644 xref: FMA:62974 xref: GAID:1162 xref: MA:0002515 xref: MESH:D007419 xref: NCIT:C32875 xref: UMLS:C0021849 {source="ncithesaurus:Intestinal_Secretion"} xref: Wikipedia:Succus_entericus is_a: UBERON:0000456 ! secretion of exocrine gland intersection_of: UBERON:0000456 ! secretion of exocrine gland intersection_of: RO:0003001 UBERON:0000160 ! produced by intestine relationship: RO:0003001 UBERON:0000160 ! produced by intestine [Term] id: UBERON:0002469 name: esophagus mucosa namespace: uberon def: "A mucosa that is part of a esophagus [Automatically generated definition]." [OBOL:automatic] synonym: "esophageal mucosa" EXACT [] synonym: "esophageal mucous membrane" EXACT [] synonym: "esophagus mucosa" EXACT [FMA:62996] synonym: "esophagus mucous membrane" EXACT [OBOL:automatic] synonym: "mucosa of esophagus" EXACT [OBOL:automatic] synonym: "mucosa of oesophagus" EXACT [OBOL:automatic] synonym: "mucous membrane of esophagus" EXACT [] synonym: "mucous membrane of oesophagus" EXACT [FMA:62996] synonym: "oesophageal mucosa" EXACT [FMA:62996] synonym: "oesophagus mucosa" EXACT [] synonym: "oesophagus mucous membrane" EXACT [OBOL:automatic] synonym: "tunica mucosa esophagi" EXACT [] synonym: "tunica mucosa oesophagi" EXACT [] xref: BTO:0002859 xref: EMAPA:26981 xref: FMA:62996 xref: MA:0002680 xref: NCIT:C32538 xref: SCTID:362127004 xref: UMLS:C0227176 {source="ncithesaurus:Esophageal_Mucosa"} is_a: UBERON:0000344 ! mucosa intersection_of: UBERON:0000344 ! mucosa intersection_of: BFO:0000050 UBERON:0001043 ! part of esophagus relationship: BFO:0000050 UBERON:0001096 ! part of wall of esophagus [Term] id: UBERON:0002481 name: bone tissue namespace: uberon def: "Skeletal tissue with a collagen-rich extracellular matrix vascularized, mineralized with hydroxyapatite and typically including osteocytes located in lacunae that communicate with one another by cell processes (in canaliculi). Bone is deposited by osteoblasts." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, PSPUB:0000170, VSAO:0000047] synonym: "calcium tissue" EXACT [] synonym: "osseous tissue" EXACT [] synonym: "osteogenic tissue" EXACT [VSAO:curator] xref: CALOHA:TS-2011 xref: EMAPA:35179 xref: FMA:224804 xref: galen:BoneTissue xref: MA:0002780 xref: MESH:D001842 xref: NCIT:C13076 xref: UMLS:C0391978 {source="ncithesaurus:Bone_Tissue"} xref: VSAO:0000047 xref: Wikipedia:Bone_tissue xref: XAO:0004040 xref: ZFA:0005621 is_a: UBERON:0004755 {source="VSAO"} ! skeletal tissue disjoint_from: UBERON:0005090 ! muscle structure relationship: BFO:0000050 UBERON:0001474 ! part of bone element relationship: RO:0002160 NCBITaxon:7742 ! only in taxon Vertebrata [Term] id: UBERON:0002506 name: iris epithelium namespace: uberon def: "An epithelium that is part of a iris [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of iris" EXACT [OBOL:automatic] synonym: "epithelium of iris" EXACT [OBOL:automatic] synonym: "epithelium pigmentosum (iris)" EXACT [FMA:58517] synonym: "iris epithelial tissue" EXACT [OBOL:automatic] synonym: "iris epithelium" EXACT [FMA:58517] synonym: "pigmented epithelium of iris" EXACT [FMA:58517] xref: EMAPA:35447 xref: FMA:58517 xref: MA:0002826 is_a: UBERON:0000488 {source="FMA"} ! atypical epithelium is_a: UBERON:0015808 ! eye epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: BFO:0000050 UBERON:0001769 ! part of iris relationship: BFO:0000050 UBERON:0001769 {source="MA"} ! part of iris relationship: BFO:0000051 GO:0048770 {source="MP"} ! has part pigment granule relationship: RO:0002433 UBERON:0001769 ! contributes to morphology of iris [Term] id: UBERON:0002511 name: trabecula carnea namespace: uberon def: "The supporting bundles of muscular fibers lining the walls of the ventricles of the heart." [MGI:monikat, MP:0004067] synonym: "ventricle trabecula carnea" EXACT [MA:0002831] xref: EMAPA:18626 xref: FMA:7269 xref: MA:0002831 xref: SCTID:118755002 xref: Wikipedia:Trabeculae_carneae is_a: UBERON:0000440 ! trabecula is_a: UBERON:0004120 ! mesoderm-derived structure relationship: BFO:0000050 UBERON:0002082 {source="WP"} ! part of cardiac ventricle relationship: RO:0002473 UBERON:0001133 ! composed primarily of cardiac muscle tissue [Term] id: UBERON:0002513 name: endochondral bone namespace: uberon def: "Replacement bone that forms within cartilage." [GO:0001958, GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, https://github.com/obophenotype/uberon/issues/54, VSAO:0000145] synonym: "ossified chondrogenic bone" EXACT [VSAO:0000145] xref: AAO:0010776 xref: AEO:0000083 xref: BTO:0002157 xref: EHDAA2:0003083 xref: FMA:24321 xref: TAO:0001591 xref: VSAO:0000145 xref: XAO:0004018 xref: ZFA:0001591 is_a: UBERON:0001474 ! bone element is_a: UBERON:0010363 {source="VSAO"} ! endochondral element intersection_of: UBERON:0001474 ! bone element intersection_of: RO:0002202 UBERON:0005863 ! develops from cartilaginous condensation relationship: RO:0002202 UBERON:0007844 {source="VSAO"} ! develops from cartilage element relationship: RO:0002285 UBERON:0002418 ! developmentally replaces cartilage tissue property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/e/ee/Hypertrophic_Zone_of_Epiphyseal_Plate.jpg" xsd:anyURI property_value: x_1.1:contributor https://github.com/cmungall property_value: x_1.1:contributor https://github.com/mellybelly property_value: x_1.1:contributor https://github.com/wdahdul [Term] id: UBERON:0002514 name: intramembranous bone namespace: uberon def: "Bone tissue forms directly within mesenchyme, and does not replace other tissues[TAO]. Intramembranous ossification is the formation of bone in which osteoblasts secrete a collagen-proteoglycan matrix that binds calcium salts and becomes calcified[GO]. Intramembranous ossification is the way flat bones and the shell of a turtle are formed[GO]. Unlike endochondral ossification, cartilage is not present during intramembranous ossification[WP]." [GO:0001957, https://github.com/obophenotype/uberon/issues/267, Wikipedia:Intramembranous_ossification] xref: EMAPA:36615 xref: TAO:0001644 xref: Wikipedia:Intramembranous_ossification xref: ZFA:0001635 is_a: UBERON:0001474 {source="VSAO"} ! bone element relationship: RO:0002202 UBERON:0003104 ! develops from mesenchyme relationship: RO:0002353 GO:0001957 ! output of intramembranous ossification [Term] id: UBERON:0002517 name: basicranium namespace: uberon def: "The base of skull is the most inferior area of the skull, composed of the endocranium and lower parts of the skull roof." [Wikipedia:Base_of_skull] synonym: "base of cranium" EXACT [] synonym: "base of skull" EXACT [FMA:52801] synonym: "cranial base" EXACT [FMA:52801, MA:0002840] xref: FMA:52801 xref: MA:0002840 xref: MESH:D019291 xref: MFMO:0000044 xref: NCIT:C12493 xref: SCTID:181890004 xref: UMLS:C0149543 {source="ncithesaurus:Base_of_the_Skull"} xref: Wikipedia:Base_of_skull is_a: UBERON:0000075 ! subdivision of skeletal system relationship: BFO:0000050 UBERON:0001703 ! part of neurocranium relationship: BFO:0000050 UBERON:0002241 ! part of chondrocranium relationship: RO:0002433 UBERON:0003128 ! contributes to morphology of cranium property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/8/81/Gray193.png" xsd:anyURI [Term] id: UBERON:0002521 name: elastic tissue namespace: uberon def: "Connective tissue composed of elastic fibers." [http://orcid.org/0000-0002-6601-2165] synonym: "elastic connective tissue" EXACT [] xref: FMA:20113 xref: GAID:926 xref: MA:0002853 xref: MESH:D004547 xref: NCIT:C32495 xref: SCTID:27197004 xref: Wikipedia:Elastic_fiber is_a: UBERON:0002384 ! connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: RO:0002473 GO:0071953 ! composed primarily of elastic fiber relationship: RO:0000086 PATO:0001171 ! has quality elastic relationship: RO:0002473 GO:0071953 ! composed primarily of elastic fiber property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/c/cb/Gray377.png" xsd:anyURI [Term] id: UBERON:0002522 name: tunica media namespace: uberon def: "The middle layer of an artery or vein. [WP,unvetted]." [Wikipedia:Tunica_media] xref: BTO:0002011 xref: EMAPA:36298 xref: FMA:55590 xref: GAID:170 xref: MA:0002855 xref: MESH:D017540 xref: NCIT:C33821 xref: SCTID:61695000 xref: UMLS:C0162867 {source="ncithesaurus:Tunica_Media"} xref: Wikipedia:Tunica_media is_a: UBERON:0004797 {source="MA"} ! blood vessel layer relationship: BFO:0000051 UBERON:0002521 {source="cjm"} ! has part elastic tissue relationship: BFO:0000051 UBERON:0004237 {source="cjm"} ! has part blood vessel smooth muscle relationship: RO:0002219 UBERON:0005734 ! surrounded by tunica adventitia of blood vessel property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/3/32/Illu_artery.jpg" xsd:anyURI [Term] id: UBERON:0002523 name: tunica intima namespace: uberon def: "The innermost layer of a blood vessel which is a lining of endothelial cells facing the lumen[Kardong]." [ISBN:0073040584, NCIT:C33820, Wikipedia:Tunica_intima] xref: BTO:0002012 xref: EMAPA:36297 xref: FMA:55589 xref: GAID:523 xref: MA:0002861 xref: MESH:D017539 xref: NCIT:C33820 xref: SCTID:8361002 xref: SCTID:87483006 xref: UMLS:C0162864 {source="ncithesaurus:Tunica_Intima"} xref: Wikipedia:Tunica_intima is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0004923 {source="FMA"} ! organ component layer relationship: BFO:0000051 UBERON:0001986 ! has part endothelium relationship: RO:0002219 UBERON:0002522 ! surrounded by tunica media relationship: RO:0002220 UBERON:0010161 {source="ISBN:0073040584"} ! adjacent to lumen of blood vessel property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/3/32/Illu_artery.jpg" xsd:anyURI [Term] id: UBERON:0002530 name: gland namespace: uberon def: "An organ that functions as a secretory or excretory organ." [MGI:csmith, MP:0002163] synonym: "glandular organ" EXACT [http://orcid.org/0000-0002-6601-2165] xref: AAO:0000212 xref: AEO:0000096 xref: BTO:0000522 xref: EFO:0000797 xref: EHDAA2:0003096 xref: EHDAA:2161 xref: EHDAA:4475 xref: EHDAA:6522 xref: EMAPA:18425 xref: FMA:7146 xref: FMA:86294 xref: galen:Gland xref: HAO:0000375 xref: MA:0003038 xref: MAT:0000021 xref: MIAA:0000021 xref: NCIT:C13319 xref: SCTID:134358001 xref: UMLS:C1285092 {source="ncithesaurus:Gland"} xref: Wikipedia:Gland xref: WikipediaCategory:Glands is_a: UBERON:0000062 ! organ relationship: RO:0002160 NCBITaxon:6072 ! only in taxon Eumetazoa relationship: RO:0002215 GO:0046903 ! capable of secretion relationship: RO:0003000 UBERON:0000463 ! produces organism substance property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/a/a1/Gray1026.png" xsd:anyURI [Term] id: UBERON:0002532 name: epiblast (generic) namespace: uberon def: "In amniote animal embryology, the epiblast is a tissue type derived either from the inner cell mass in mammals or the blastodisc in birds and reptiles. It lies above the hypoblast. In mammalian embryogenesis, the columnar cells of the epiblast are adjacent to the trophoblast, while the cuboidal cells of the hypoblast are closer to the blastocoele. The epiblast, whilst referred to as the primary ectoderm, differentiates to form all three layers of the trilaminar germ disc in a process called gastrulation[WP]. The outer of the two layers of the blastoderm that form during gastrulation, corresponding to primitive ectoderm during gastrulation and to the definitive ectoderm after gastrulation[ZFA]." [Wikipedia:Epiblast, ZFIN:curator] synonym: "epiblast" EXACT [VHOG:0000243] xref: BTO:0004593 xref: FMA:296704 xref: MAT:0000067 xref: MIAA:0000067 xref: VHOG:0000243 xref: Wikipedia:Epiblast is_a: UBERON:0002050 ! embryonic structure relationship: BFO:0000051 CL:0000352 ! has part epiblast cell property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/e/e3/Gray21.png" xsd:anyURI [Term] id: UBERON:0002533 name: post-anal tail bud namespace: uberon def: "The rapidly proliferating mass of cells at the caudal extremity of the embryo; remnant of the primitive node." [BTO:0001445] synonym: "tail bud" EXACT [ZFA:0000077] synonym: "tailbud" EXACT [] xref: AAO:0011104 xref: BTO:0001445 xref: EFO:0002748 xref: EHDAA2:0001976 xref: EHDAA:1595 xref: EMAPA:16580 xref: MAT:0000070 xref: MIAA:0000070 xref: TAO:0000077 xref: VHOG:0000201 xref: XAO:0000107 xref: ZFA:0000077 is_a: UBERON:0002050 ! embryonic structure relationship: RO:0002160 NCBITaxon:7742 ! only in taxon Vertebrata [Term] id: UBERON:0002536 name: arthropod sensillum namespace: uberon def: "Sense organ embedded in the integument and consisting of one or a cluster of sensory neurons and associated sensory structures, support cells and glial cells forming a single organised unit with a largely bona-fide boundary.[FBbt]." [FBbt:00007152, Wikipedia:Sensillum] synonym: "sensillum" EXACT [FBbt:00007152, HAO:0000933] xref: BTO:0001237 xref: EFO:0000939 xref: HAO:0000933 xref: MAT:0000163 xref: MIAA:0000163 xref: TGMA:0000540 xref: Wikipedia:Sensillum is_a: UBERON:0000020 ! sense organ relationship: BFO:0000050 UBERON:0001016 ! part of nervous system relationship: RO:0002160 NCBITaxon:6656 ! only in taxon Arthropoda [Term] id: UBERON:0002537 name: hermaphrodite gonad namespace: uberon def: "A gonad with both testicular and ovarian aspects[WP]." [Wikipedia:Ovotestis] synonym: "hermaphrodite genitalia" EXACT [GO:0040035] xref: BTO:0000981 xref: EFO:0000971 xref: MAT:0000165 xref: MIAA:0000165 xref: WBbt:0005178 xref: Wikipedia:Ovotestis is_a: UBERON:0000991 ! gonad intersection_of: UBERON:0000991 ! gonad intersection_of: RO:0002215 GO:0007283 ! capable of spermatogenesis intersection_of: RO:0002215 GO:0048477 ! capable of oogenesis relationship: BFO:0000050 UBERON:0007197 ! part of hermaphroditic organism relationship: RO:0002215 GO:0007283 ! capable of spermatogenesis relationship: RO:0002215 GO:0048477 ! capable of oogenesis [Term] id: UBERON:0002539 name: pharyngeal arch namespace: uberon def: "One of a series of paired bulges that develop along the lateral walls of the foregut. The pharyngeal arches have developmental contributions from endoderm, mesoderm, and neural crest cells and are separated by anterior lateral endoderm out-pockets known as pharyngeal pouches." [http://orcid.org/0000-0002-6601-2165, PMID:16313389, ZFA:yb] xref: AAO:0010359 xref: BTO:0001785 xref: EFO:0000959 xref: EHDAA:571 xref: EMAPA:16117 xref: FMA:293015 xref: GAID:1292 xref: MAT:0000242 xref: MESH:D001934 xref: MIAA:0000242 xref: NCIT:C34249 xref: SCTID:308766004 xref: TAO:0001306 xref: UMLS:C0080322 {source="ncithesaurus:Pharyngeal_Arch"} xref: VHOG:0000155 xref: Wikipedia:Pharyngeal_arch xref: XAO:0000096 xref: ZFA:0001306 is_a: UBERON:0000481 ! multi-tissue structure is_a: UBERON:0010188 {source="EHDAA2"} ! protuberance is_a: UBERON:0010314 ! structure with developmental contribution from neural crest relationship: BFO:0000050 NCBITaxon:6072 ! part of Eumetazoa relationship: BFO:0000050 UBERON:0008814 ! part of pharyngeal arch system relationship: BFO:0000050 UBERON:0008816 {source="PMID:16313389"} ! part of embryonic head relationship: RO:0002160 NCBITaxon:7711 {source="http://tolweb.org/Chordata/2499"} ! only in taxon Chordata relationship: RO:0002256 UBERON:0007690 {source="PMID:16313389"} ! developmentally induced by early pharyngeal endoderm property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/8/8b/Gray41.png" xsd:anyURI [Term] id: UBERON:0002546 name: cranial placode namespace: uberon def: "Ectodermal placode that develops in the head into a part of the sensory nervous system. With a few exceptions (lens, adenohypophyseal), cranial placodes are neurogenic." [http://www.ncbi.nlm.nih.gov/books/NBK53175/, https://github.com/obophenotype/uberon/issues/135, https://github.com/seger/aao/issues/4, https://orcid.org/0000-0002-6601-2165, https://sourceforge.net/p/obo/xenopus-anatomy-xao-term-requests/11/] synonym: "ectodermal cranial placode" EXACT [UBERON:cjm] xref: AAO:0010466 xref: EFO:0001650 xref: FMA:293966 xref: MAT:0000369 xref: MIAA:0000369 xref: XAO:0000305 is_a: UBERON:0005085 {source="cjm"} ! ectodermal placode relationship: BFO:0000050 UBERON:0000033 ! part of head relationship: RO:0002160 NCBITaxon:7711 {source="PMID:11523831", source="PMID:22512454"} ! only in taxon Chordata [Term] id: UBERON:0002548 name: larva namespace: uberon def: "A distinct juvenile form many animals undergo before metamorphosis into adults. Animals with indirect development such as insects, amphibians, or cnidarians typically have a larval phase of their life cycle." [Wikipedia:Larva] synonym: "larval organism" EXACT [TAO:0002048] xref: AEO:0000126 xref: BTO:0000707 xref: FBbt_00001727 xref: HAO:0000459 xref: TAO:0002048 xref: Wikipedia:Larva is_a: UBERON:0000468 ! multicellular organism intersection_of: UBERON:0000468 ! multicellular organism intersection_of: RO:0002491 UBERON:0000069 ! existence starts and ends during larval stage relationship: RO:0000086 PATO:0001185 ! has quality larval relationship: RO:0002491 UBERON:0000069 ! existence starts and ends during larval stage [Term] id: UBERON:0002553 name: anatomical cavity namespace: uberon def: "Anatomical space which contains portions of one or more body substances and is bounded by the internal surface of one maximally connected anatomical structure. Examples: cranial cavity, pharyngeal recess space, nasal cavity, tooth socket, cavity of serous sac, lumen of stomach, lumen of artery, fornix of vagina." [FMA:67552] xref: BIRNLEX:1011 xref: EMAPA:37442 {source="MA:th"} xref: FMA:67552 xref: galen:Cavity xref: MA:0002447 xref: NCIT:C34007 is_a: UBERON:0000464 ! anatomical space relationship: RO:0001015 UBERON:0000463 ! location of organism substance [Term] id: UBERON:0002558 name: organ cavity namespace: uberon synonym: "cavity of organ" EXACT [FMA:12237] xref: BIRNLEX:1019 xref: FMA:12237 xref: SCTID:362606005 is_a: UBERON:0002553 ! anatomical cavity [Term] id: UBERON:0002561 name: lumen of central nervous system namespace: uberon def: "The cavity that is enclosed by the central nervous system. In vertebrates this is the cavity that includes as parts ventricular cavities and the central canal of the spinal cord that develops from the lumen of the neura tube." [https://orcid.org/0000-0002-6601-2165] synonym: "cavity of neuraxis" EXACT [FMA:75007] synonym: "cavity of ventricular system of neuraxis" EXACT [FMA:75007] synonym: "neuraxis cavity" EXACT [FMA:75007] synonym: "neuraxis lumen" EXACT [] xref: BIRNLEX:1029 xref: FMA:75007 is_a: UBERON:0002558 ! organ cavity intersection_of: UBERON:0002558 ! organ cavity intersection_of: RO:0002572 UBERON:0001017 ! luminal space of central nervous system relationship: RO:0002202 UBERON:0003842 {gci_filler="NCBITaxon:7742", gci_relation="BFO:0000050", source="cjm"} ! develops from neural tube lumen relationship: RO:0002572 UBERON:0001017 ! luminal space of central nervous system [Term] id: UBERON:0002616 name: regional part of brain namespace: uberon def: "Anatomical divisons of the brain according to one or more criteria, e.g. cytoarchitectural, gross anatomy. Parts may be contiguous in 3D or not, e.g., basal ganglia." [BIRNLEX:1167] synonym: "anatomical structure of brain" EXACT [OBOL:automatic] synonym: "biological structure of brain" EXACT [OBOL:automatic] synonym: "brain anatomical structure" EXACT [OBOL:automatic] synonym: "brain biological structure" EXACT [OBOL:automatic] synonym: "brain part" EXACT [] synonym: "neuraxis segment" EXACT [FMA:55676] synonym: "neuroanatomical region" EXACT [] synonym: "segment of brain" EXACT [BIRNLEX:1167] xref: BIRNLEX:1167 xref: FMA:55676 xref: NCIT:C13031 xref: SCTID:384763002 xref: UMLS:C0445620 {source="ncithesaurus:Brain_Part"} is_a: UBERON:0000073 ! regional part of nervous system is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: BFO:0000050 UBERON:0000955 ! part of brain relationship: BFO:0000050 UBERON:0000955 ! part of brain relationship: RO:0002473 UBERON:0003714 ! composed primarily of neural tissue [Term] id: UBERON:0002726 name: cervical spinal cord namespace: uberon def: "A spinal cord segment that adjacent_to a cervical region." [OBOL:automatic] synonym: "cervical segment of spinal cord" EXACT [FMA:71166] synonym: "cervical segments of spinal cord [1-8]" EXACT [FMA:71166] synonym: "cervical spinal cord" EXACT [FMA:71166] xref: BIRNLEX:1499 xref: FMA:71166 xref: MA:0003081 xref: NCIT:C12892 xref: neuronames:1654 xref: SCTID:180960003 xref: UMLS:C0581619 {source="BIRNLEX:1499", source="ncithesaurus:Cervical_Spinal_Cord"} xref: UMLS:C1278837 {source="BIRNLEX:1499"} is_a: UBERON:0005844 ! spinal cord segment intersection_of: UBERON:0005844 ! spinal cord segment intersection_of: RO:0002220 UBERON:0005434 ! adjacent to cervical region relationship: RO:0002160 NCBITaxon:8287 ! only in taxon Sarcopterygii relationship: RO:0002220 UBERON:0005434 ! adjacent to cervical region [Term] id: UBERON:0002925 name: trigeminal nucleus namespace: uberon def: "A nucleus of brain that is part of a trigeminal nuclear complex." [OBOL:automatic] synonym: "nucleus of trigeminal nuclear complex" EXACT [FMA:71247] synonym: "trigeminal nuclear complex nucleus" EXACT [FMA:71247] synonym: "trigeminal nucleus" EXACT [FMA:71248] synonym: "trigeminal V nucleus" EXACT [MA:0001028] xref: BM:V xref: BTO:0001074 xref: CALOHA:TS-2077 xref: EMAPA:35883 xref: EV:0100271 xref: FMA:71247 xref: GAID:604 xref: http://uri.neuinfo.org/nif/nifstd/nifext_11 xref: MA:0001028 xref: MESH:D014278 xref: NCIT:C12807 xref: SCTID:280164007 xref: UMLS:C0040999 {source="ncithesaurus:Trigeminal_Nucleus"} xref: VHOG:0001353 is_a: UBERON:0000126 ! cranial nerve nucleus intersection_of: UBERON:0002308 ! nucleus of brain intersection_of: BFO:0000050 UBERON:0007641 ! part of trigeminal nuclear complex relationship: BFO:0000050 UBERON:0007641 ! part of trigeminal nuclear complex relationship: extends_fibers_into UBERON:0001645 ! trigeminal nerve [Term] id: UBERON:0003023 name: pontine tegmentum namespace: uberon def: "Dorsal portion of the pons, containing cranial nervee nuclei, ascending and descending tracts and reticular nuclei. It is continuous with the reticular formation of the medulla (Carpenter, A Core Text of Neuroanatomy, 3rd ed, 1985, pg 133)." [BIRNLEX:923] synonym: "dorsal pons" EXACT [] synonym: "dorsal portion of pons" EXACT [FMA:71108] synonym: "tegmental portion of pons" EXACT [FMA:71108] synonym: "tegmentum of pons" EXACT [FMA:71108] xref: BAMS:PTg xref: BIRNLEX:923 xref: DHBA:12416 xref: FMA:71108 xref: HBA:9135 xref: neuronames:557 {source="BIRNLEX:923"} xref: SCTID:362401009 xref: UMLS:C0228426 {source="BIRNLEX:923"} xref: Wikipedia:Pontine_tegmentum is_a: UBERON:0000064 ! organ part is_a: UBERON:0004121 ! ectoderm-derived structure relationship: BFO:0000050 UBERON:0000988 ! part of pons relationship: BFO:0000051 UBERON:0002047 ! has part pontine raphe nucleus relationship: BFO:0000051 UBERON:0002128 ! has part superior olivary complex relationship: BFO:0000051 UBERON:0002148 ! has part locus ceruleus relationship: BFO:0000051 UBERON:0002149 ! has part superior salivatory nucleus property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/Allen_F_Brain.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/Allen_M_Brain.glb" xsd:anyURI property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/9/9c/Brainstem_Abducens.png" xsd:anyURI [Term] id: UBERON:0003037 name: septum namespace: uberon def: "A wall, dividing a cavity or structure into smaller ones[WP]." [Wikipedia:Septum] xref: AAO:0011127 xref: FMA:86461 xref: Wikipedia:Septum is_a: UBERON:0000061 ! anatomical structure relationship: RO:0001025 UBERON:0002553 ! located in anatomical cavity [Term] id: UBERON:0003038 name: thoracic spinal cord namespace: uberon def: "The thoracic nerves are the spinal nerves emerging from the thoracic vertebrae. [WP,unvetted]." [Wikipedia:Thoracic_spinal_cord] synonym: "thoracic region of spinal cord" EXACT [FMA:71167] synonym: "thoracic segment of spinal cord" EXACT [FMA:71167] synonym: "thoracic segments of spinal cord [1-12]" EXACT [FMA:71167] synonym: "thoracic spinal cord" EXACT [FMA:71167] xref: BIRNLEX:966 xref: FMA:71167 xref: MA:0003082 xref: NCIT:C12894 xref: neuronames:1718 xref: SCTID:278750009 xref: UMLS:C0581620 {source="ncithesaurus:Thoracic_Spinal_Cord", source="BIRNLEX:966"} xref: Wikipedia:Thoracic_spinal_cord is_a: UBERON:0005844 ! spinal cord segment intersection_of: UBERON:0005844 ! spinal cord segment intersection_of: BFO:0000050 UBERON:0000915 ! part of thoracic segment of trunk relationship: BFO:0000050 UBERON:0008231 ! part of dorsal thoracic segment of trunk property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/6/68/Gray820.png" xsd:anyURI [Term] id: UBERON:0003052 name: midbrain-hindbrain boundary namespace: uberon def: "The part of the brain that is the morphological boundary between the midbrain and hindbrain and that is the location of an organizing center which patterns the midbrain and hindbrain primordia of the neural plate." [GO:0021555] synonym: "MHB" EXACT [] synonym: "mid-hindbrain boundary" EXACT [] synonym: "mid-hindbrain junction" EXACT [] synonym: "midbrain hindbrain boundary" EXACT [] xref: AAO:0011064 xref: DMBA:16810 xref: EHDAA2:0004395 xref: EHDAA:5789 xref: EMAPA:32857 xref: NCIT:C93172 xref: neuronames:2076 xref: TAO:0000042 xref: VHOG:0000649 xref: XAO:0000016 xref: ZFA:0000042 is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0007651 ! anatomical junction intersection_of: UBERON:0007651 ! anatomical junction intersection_of: RO:0002131 UBERON:0001891 ! overlaps midbrain intersection_of: RO:0002131 UBERON:0002028 ! overlaps hindbrain relationship: BFO:0000050 UBERON:0000955 {source="ZFA"} ! part of brain relationship: RO:0002131 UBERON:0001891 ! overlaps midbrain relationship: RO:0002131 UBERON:0002028 ! overlaps hindbrain relationship: RO:0002495 UBERON:0009615 {source="ZFA"} ! immediate transformation of midbrain hindbrain boundary neural plate [Term] id: UBERON:0003055 name: periderm namespace: uberon def: "A temporary epithelium that derives from the outer layer of the ectdoerm and is shed once the inner layer differentiates to form a true epidermis." [ISBN:9780878932504] synonym: "skin periderm" EXACT [EHDAA2:0001846] xref: EHDAA2:0001846 xref: EHDAA:6538 xref: FMA:295662 xref: NCIT:C34247 xref: TAO:0001185 xref: UMLS:C1518973 {source="ncithesaurus:Periderm"} xref: VHOG:0001680 xref: XAO:0000029 xref: ZFA:0001185 is_a: UBERON:0000487 {source="EHDAA2"} ! simple squamous epithelium is_a: UBERON:0010371 ! ecto-epithelium relationship: BFO:0000050 UBERON:0002199 {source="EHDAA2"} ! part of integument relationship: RO:0002202 UBERON:0007383 {source="ZFA"} ! develops from enveloping layer of ectoderm [Term] id: UBERON:0003056 name: pre-chordal neural plate namespace: uberon def: "The portion of neural plate anterior to the mid-hindbrain junction." [XB:curator] xref: AAO:0011084 xref: TAO:0007016 xref: VHOG:0001200 xref: XAO:0000045 xref: ZFA:0007016 is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0005291 ! embryonic tissue relationship: BFO:0000050 UBERON:0003075 ! part of neural plate relationship: BSPO:0000096 UBERON:0009615 ! anterior to midbrain hindbrain boundary neural plate [Term] id: UBERON:0003057 name: chordal neural plate namespace: uberon def: "The portion of neural plate posterior to the mid-hindbrain junction." [XB:curator] xref: TAO:0007017 xref: VHOG:0001201 xref: XAO:0000046 xref: ZFA:0007017 is_a: UBERON:0002050 ! embryonic structure relationship: BFO:0000050 UBERON:0003075 ! part of neural plate relationship: BSPO:0000099 UBERON:0009615 ! posterior to midbrain hindbrain boundary neural plate [Term] id: UBERON:0003059 name: presomitic mesoderm namespace: uberon def: "Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form." [ZFIN:curator] synonym: "segmental plate" EXACT [] synonym: "unsegmented paraxial mesoderm" EXACT [https://orcid.org/0000-0002-6601-2165] xref: AAO:0011086 xref: EFO:0001982 xref: EMAPA:16189 xref: EMAPA:16752 xref: TAO:0000279 xref: VHOG:0000559 xref: XAO:0000057 xref: ZFA:0000279 is_a: UBERON:0006598 ! presumptive structure intersection_of: UBERON:0005423 ! developing anatomical structure intersection_of: RO:0002387 UBERON:0002329 ! has potential to develop into somite intersection_of: RO:0002495 UBERON:0007282 ! immediate transformation of presumptive segmental plate relationship: BFO:0000050 UBERON:0003077 ! part of paraxial mesoderm relationship: RO:0002387 UBERON:0002329 ! has potential to develop into somite relationship: RO:0002495 UBERON:0007282 {source="Bgee:AN"} ! immediate transformation of presumptive segmental plate [Term] id: UBERON:0003060 name: pronephric duct namespace: uberon def: "In mammals, the pronephric duct is the predecessor of the Wolffian duct[WP]." [Wikipedia:Pronephric_duct] xref: AAO:0011088 xref: NCIT:C34279 xref: SCTID:361406002 xref: TAO:0000150 xref: UMLS:C1283945 {source="ncithesaurus:Pronephric_Duct"} xref: VHOG:0000082 xref: Wikipedia:Pronephric_duct xref: XAO:0000063 xref: ZFA:0000150 is_a: UBERON:0009201 {source="GO"} ! nephric duct is_a: UBERON:0012275 ! meso-epithelium relationship: BFO:0000050 UBERON:0002120 ! part of pronephros relationship: RO:0002202 UBERON:0003064 {source="Wikipedia"} ! develops from intermediate mesoderm relationship: RO:0002202 UBERON:0005721 {source="XAO"} ! develops from pronephric mesoderm [Term] id: UBERON:0003061 name: blood island namespace: uberon def: "Blood islands are structures in the developing embryo which lead to many different parts of the circulatory system. They primarily derive from plexuses formed from angioblasts. Within them, vacuoles appear through liquefaction of the central part of the syncytium into plasma. The lumen of the blood vessels thus formed is probably intracellular. The flattened cells at the periphery form the endothelium. The nucleated red blood corpuscles develop either from small masses of the original angioblast left attached to the inner wall of the lumen or directly from the flat endothelial cells. In either case the syncytial mass thus formed projects from and is attached to the wall of the vessel. Such a mass is known as a blood island and hemoglobin gradually accumulates within it. Later the cells on the surface round up, giving the mass a mulberry-like appearance. Then the red blood cells break loose and are carried away in the plasma. Such free blood cells continue to divide. Blood islands have been seen in the area vasculosa in the omphalomesenteric vein and arteries, and in the dorsal aorta[WP, unvetted]." [Wikipedia:Blood_island_of_umbilical_vesicle] xref: AAO:0011006 xref: EFO:0003489 xref: EHDAA:207 xref: NCIT:C34113 xref: TAO:0000094 xref: TE:E5.11.2.0.0.0.4 xref: UMLS:C1511224 {source="ncithesaurus:Blood_Island"} xref: VHOG:0000085 xref: Wikipedia:Blood_island_of_umbilical_vesicle xref: XAO:0000067 xref: ZFA:0000094 is_a: UBERON:0006598 ! presumptive structure relationship: RO:0002202 UBERON:0003081 ! develops from lateral plate mesoderm relationship: RO:0002387 UBERON:0002390 ! has potential to develop into hematopoietic system [Term] id: UBERON:0003063 name: prechordal plate namespace: uberon def: "A horseshoe-shaped thickening of the endoderm at the cranial (rostral) end of the primitive streak formed by the involution of Spemann's organizer cells which, together with the notochord, induces the formation of the neural plate from the overlying ectodermal cells and contributes mesodermal type cells to the surrounding tissue." [ISBN:0838580343, MP:0004387] xref: AAO:0011085 xref: EHDAA2:0001493 xref: EHDAA:181 xref: FMA:295532 xref: TAO:0000060 xref: VHOG:0000086 xref: Wikipedia:Prechordal_plate xref: XAO:0000079 xref: ZFA:0000060 is_a: UBERON:0002050 ! embryonic structure relationship: BFO:0000050 UBERON:0003068 {source="ZFA"} ! part of axial mesoderm relationship: RO:0002494 UBERON:0034878 ! transformation of prechordal mesoderm [Term] id: UBERON:0003064 name: intermediate mesoderm namespace: uberon def: "The intermediate mesoderm is located between the lateral mesoderm and the paraxial mesoderm. It develops into the kidney and gonads." [GOC:curators, Wikipedia:Intermediate_mesoderm] xref: AAO:0010575 xref: EMAPA:16056 xref: EMAPA:16178 xref: FMA:293147 xref: NCIT:C34193 xref: SCTID:361476001 xref: TAO:0001206 xref: UMLS:C1284010 {source="ncithesaurus:Intermediate_Mesoderm"} xref: VHOG:0000087 xref: Wikipedia:Intermediate_mesoderm xref: XAO:0000085 xref: ZFA:0001206 is_a: UBERON:0002050 ! embryonic structure relationship: BFO:0000050 UBERON:0000926 {source="AAO"} ! part of mesoderm relationship: BFO:0000050 UBERON:0005256 {source="EMAPA"} ! part of trunk mesenchyme relationship: RO:0002202 UBERON:0000926 {source="XAO"} ! develops from mesoderm relationship: RO:0002220 UBERON:0003077 ! adjacent to paraxial mesoderm relationship: RO:0002220 UBERON:0003081 ! adjacent to lateral plate mesoderm property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png" xsd:anyURI [Term] id: UBERON:0003067 name: dorsolateral placode namespace: uberon def: "Lateral neurogenic placodes positioned dorsal of the epibranchial placodes." [ZFIN:curator] xref: TAO:0001310 xref: VHOG:0000103 xref: XAO:0000187 xref: ZFA:0001310 is_a: UBERON:0009955 {source="NCBIBook:NBK53175"} ! neurogenic placode relationship: BSPO:0000098 UBERON:0003078 ! dorsal to epibranchial placode [Term] id: UBERON:0003068 name: axial mesoderm namespace: uberon def: "The axial mesoderm includes the prechordal mesoderm and the chordamesoderm. It gives rise to the prechordal plate and to the notochord." [GO:0048318, Wikipedia:Chordamesoderm] xref: AAO:0011017 xref: EFO:0003647 xref: TAO:0001204 xref: VHOG:0000107 xref: Wikipedia:Chordamesoderm xref: XAO:0000205 xref: ZFA:0001204 is_a: UBERON:0002050 ! embryonic structure relationship: BFO:0000050 UBERON:0000926 ! part of mesoderm relationship: RO:0002160 NCBITaxon:7711 ! only in taxon Chordata relationship: RO:0002202 UBERON:0000926 ! develops from mesoderm property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png" xsd:anyURI [Term] id: UBERON:0003070 name: trigeminal placode complex namespace: uberon def: "A neurogenic placode that arises at the level of the midbrain-hindbrain boundary and develops into a trigeminal ganglion." [http://orcid.org/0000-0002-6601-2165, https://github.com/obophenotype/uberon/issues/693, PMID:22512454] synonym: "trigeminal placode" EXACT [EHDAA2:0004209, VHOG:0000109, XAO:0000225, ZFA:0000162] synonym: "trigeminal V placode" EXACT [] xref: EFO:0003433 xref: EHDAA2:0004209 xref: TAO:0000162 xref: VHOG:0000109 xref: XAO:0000225 xref: ZFA:0000162 is_a: UBERON:0003067 {source="ISBN:0471888893"} ! dorsolateral placode relationship: RO:0002385 UBERON:0003942 ! has potential to developmentally contribute to somatosensory system property_value: x_1.1:contributor https://github.com/ANiknejad property_value: x_1.1:contributor https://github.com/cmungall property_value: x_1.1:contributor https://github.com/mellybelly [Term] id: UBERON:0003071 name: eye primordium namespace: uberon def: "Portion of tissue that is part of the anterior neural keel and will form the optic vesicle[ZFA]. A paired ectodermal placode that becomes invaginated to form the embryonic lens vesicles." [GO:0046619, ZFA:0000570] synonym: "eye placode" EXACT [OBOL:automatic] synonym: "occular primordium" EXACT [] synonym: "ocular primordium" EXACT [] synonym: "optic placode" EXACT [GO:0046619] synonym: "optic placode of camera-type eye" EXACT [GO:0046619, https://orcid.org/0000-0002-6601-2165] synonym: "optic primordium" EXACT [] xref: AAO:0011038 xref: EFO:0003541 xref: EHDAA2:0004431 xref: TAO:0000570 xref: XAO:0000227 xref: XAO:0004090 xref: ZFA:0000570 is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium is_a: UBERON:0001048 ! primordium is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0006598 ! presumptive structure is_a: UBERON:0010371 ! ecto-epithelium intersection_of: UBERON:0001048 ! primordium intersection_of: RO:0002387 UBERON:0000019 ! has potential to develop into camera-type eye relationship: BFO:0000050 UBERON:0003056 {source="PMID:16496288", source="XAO"} ! part of pre-chordal neural plate relationship: RO:0002202 UBERON:0003056 ! develops from pre-chordal neural plate relationship: RO:0002387 UBERON:0000019 ! has potential to develop into camera-type eye [Term] id: UBERON:0003072 name: optic cup namespace: uberon def: "Multi-tissue structure that is comprised of neural and non-neural epithelial layers which will form the retina and retinal pigmented epithelium of the mature eye[ZFA]. double walled structured formed by expansion and invagination of the distal end of the optic vesicle that develops into the pigmented and sensory layers of the retina while the mouth of the optic cup eventually forms the pupil of the eye[MP]." [MP:0004269, Wikipedia:Optic_cup_(embryology), ZFA:0001202] xref: BTO:0005351 xref: EHDAA2:0001303 xref: EHDAA:2912 xref: EMAPA:16674 xref: NCIT:C34233 xref: SCTID:308789007 xref: TAO:0001202 xref: UMLS:C0231109 {source="ncithesaurus:Optic_Cup"} xref: VHOG:0000167 xref: ZFA:0001202 is_a: UBERON:0000481 ! multi-tissue structure is_a: UBERON:0004121 ! ectoderm-derived structure relationship: BFO:0000050 NCBITaxon:6072 ! part of Eumetazoa relationship: BFO:0000050 UBERON:0010312 {source="ZFA"} ! part of immature eye relationship: RO:0002202 UBERON:0004128 {source="ZFA"} ! develops from optic vesicle relationship: RO:0002256 UBERON:0003073 ! developmentally induced by lens placode [Term] id: UBERON:0003073 name: lens placode namespace: uberon def: "A thickened portion of ectoderm which serves as the precursor to the lens. SOX2 and Pou2f1 are involved in its development[WP]." [Wikipedia:Lens_placode, ZFIN:curator] xref: AAO:0011055 xref: EFO:0003494 xref: EHDAA2:0000982 xref: EHDAA:2908 xref: EMAPA:16672 xref: FMA:296767 xref: NCIT:C34202 xref: TAO:0000122 xref: UMLS:C1517770 {source="ncithesaurus:Lens_Placodes"} xref: VHOG:0000166 xref: Wikipedia:Lens_placode xref: XAO:0000240 xref: ZFA:0000122 is_a: UBERON:0002546 ! cranial placode is_a: UBERON:0006598 ! presumptive structure is_a: UBERON:0010312 ! immature eye is_a: UBERON:0011814 {source="NCBIBook:NBK53175"} ! non-neurogenic ectodermal placode intersection_of: UBERON:0005085 ! ectodermal placode intersection_of: RO:0002387 UBERON:0000965 ! has potential to develop into lens of camera-type eye relationship: BFO:0000050 UBERON:0010312 {source="ZFA"} ! part of immature eye relationship: RO:0002256 UBERON:0004128 ! developmentally induced by optic vesicle relationship: RO:0002387 UBERON:0000965 ! has potential to develop into lens of camera-type eye property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/2/2f/Gray864.png" xsd:anyURI [Term] id: UBERON:0003074 name: mesonephric duct namespace: uberon def: "Paired organ that connects the primitive kidney Wolffian body (or mesonephros) to the cloaca and serves as the anlage for certain male reproductive organs. the Wolffian duct is what remains of the pronephric duct after the atrophy of the pronephros[WP]. In Zebrafish: Duct of the adult kidney (mesonephros), present bilaterally ventral to the somites and leading to the cloacal chamber[ZFA]." [https://github.com/obophenotype/uberon/issues/28, Wikipedia:Mesonephric_duct, ZFIN:curator] synonym: "Wolffian duct" EXACT [GOC:yaf, Wikipedia:Wolffian_duct, ZFA:0000546] xref: AAO:0000637 xref: EHDAA2:0001243 xref: EHDAA:1590 xref: EMAPA:16577 xref: GAID:1315 xref: MESH:D014928 xref: NCIT:C26469 xref: SCTID:308800003 xref: TAO:0000546 xref: UMLS:C0043204 {source="ncithesaurus:Mesonephric_Duct"} xref: VHOG:0000082 xref: Wikipedia:Mesonephric_duct xref: XAO:0000242 xref: ZFA:0000546 is_a: UBERON:0000083 ! mesonephric tubule is_a: UBERON:0009201 {source="GO"} ! nephric duct relationship: RO:0002202 UBERON:0003060 ! develops from pronephric duct relationship: RO:0002202 UBERON:0005792 {source="EHDAA2"} ! develops from nephric ridge property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/6/6d/Gray1109.png" xsd:anyURI property_value: x_1.1:contributor https://github.com/cmungall property_value: x_1.1:contributor https://github.com/rfoulger [Term] id: UBERON:0003075 name: neural plate namespace: uberon def: "A region of embryonic ectodermal cells that lie directly above the notochord. During neurulation, they change shape and produce an infolding of the neural plate (the neural fold) that then seals to form the neural tube[XAO]. The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium[ZFA]." [ISBN:0815318960, OMD:neural+plate, Wikipedia:Neural_plate, ZFIN:curator] xref: AAO:0011072 xref: BTO:0001765 xref: DHBA:10153 xref: DMBA:15565 xref: EHDAA:346 xref: EHDAA:902 xref: EMAPA:35593 xref: FMA:293879 xref: NCIT:C34225 xref: neuronames:1362 xref: RETIRED_EHDAA2:0001252 xref: TAO:0000132 xref: UMLS:C0920623 {source="ncithesaurus:Neural_Plate"} xref: VHOG:0000068 xref: Wikipedia:Neural_plate xref: XAO:0000249 xref: ZFA:0000132 is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0010371 ! ecto-epithelium is_a: UBERON:0016879 ! future central nervous system relationship: RO:0002160 NCBITaxon:7711 {source="GOTAX:0000352"} ! only in taxon Chordata relationship: RO:0002256 UBERON:0002328 {source="Wikipedia"} ! developmentally induced by notochord relationship: RO:0002495 UBERON:0007284 {source="Bgee:AN"} ! immediate transformation of presumptive neural plate property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png" xsd:anyURI [Term] id: UBERON:0003076 name: posterior neural tube namespace: uberon xref: AAO:0011082 xref: TAO:0007037 xref: VHOG:0001383 xref: XAO:0000250 xref: ZFA:0007037 is_a: UBERON:0002050 ! embryonic structure disjoint_from: UBERON:0003080 {source="lexical"} ! anterior neural tube relationship: BFO:0000050 UBERON:0001049 ! part of neural tube relationship: RO:0002202 UBERON:0003057 ! develops from chordal neural plate [Term] id: UBERON:0003077 name: paraxial mesoderm namespace: uberon def: "The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube[GO]." [GO:0048339, https://github.com/obophenotype/uberon/issues/30] synonym: "paraxial mesenchyme" EXACT [https://github.com/obophenotype/uberon/issues/30, https://github.com/obophenotype/uberon/wiki/The-neural-crest, ZFA:0000255] synonym: "somitic mesoderm" EXACT [ISBN:9780878932504] xref: AAO:0010568 xref: EFO:0003515 xref: EMAPA:16183 xref: EMAPA:16751 xref: FMA:293145 xref: NCIT:C34244 xref: SCTID:361475002 xref: TAO:0000255 xref: UMLS:C1284009 {source="ncithesaurus:Paraxial_Mesoderm"} xref: VHOG:0000114 xref: Wikipedia:Paraxial_mesoderm xref: XAO:0000259 xref: ZFA:0000255 is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue is_a: UBERON:0015212 ! lateral structure relationship: BSPO:0000126 UBERON:0000922 ! in lateral side of embryo relationship: RO:0002488 UBERON:0000109 ! existence starts during gastrula stage relationship: RO:0002495 UBERON:0007285 {source="Bgee:AN"} ! immediate transformation of presumptive paraxial mesoderm property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png" xsd:anyURI [Term] id: UBERON:0003078 name: epibranchial placode namespace: uberon def: "Focal thickenings of the embryonic ectoderm that form immediately dorsal and caudal of the clefts between the pharyngeal arches and that produce the neuroblasts that migrate and condense to form the distal cranial ganglia." [VHOG:0000117] xref: AAO:0011036 xref: EFO:0003455 xref: FMA:293968 xref: TAO:0001294 xref: VHOG:0000117 xref: XAO:0000284 xref: ZFA:0001294 is_a: UBERON:0009955 {source="NCBIBook:NBK53175", source="ZFA"} ! neurogenic placode relationship: BFO:0000050 UBERON:0000010 {source="ZFA"} ! part of peripheral nervous system relationship: RO:0002202 UBERON:0000076 {source="EHDAA2-abduced"} ! develops from external ectoderm relationship: RO:0002385 UBERON:0002410 ! has potential to developmentally contribute to autonomic nervous system [Term] id: UBERON:0003080 name: anterior neural tube namespace: uberon xref: AAO:0011012 xref: TAO:0007038 xref: VHOG:0001384 xref: XAO:0000307 xref: ZFA:0007038 is_a: UBERON:0002050 ! embryonic structure relationship: BFO:0000050 UBERON:0001049 ! part of neural tube relationship: RO:0002202 UBERON:0003056 ! develops from pre-chordal neural plate [Term] id: UBERON:0003081 name: lateral plate mesoderm namespace: uberon def: "Portion of the middle of the three primary germ layers of the embryo that resides on the periphery of the embryo, is continuous with the extra-embryonic mesoderm, splits into two layers enclosing the intra-embryonic coelom, and gives rise to body wall structures[MP]." [MP:0010117, Wikipedia:Lateral_plate_mesoderm] synonym: "lateral mesoderm" EXACT [GO:0048368] xref: AAO:0010574 xref: EHDAA2:0000919 xref: EHDAA:379 xref: EMAPA:16179 xref: FMA:293149 xref: NCIT:C34199 xref: SCTID:361477005 xref: TAO:0000121 xref: UMLS:C1517749 {source="ncithesaurus:Lateral_Mesoderm"} xref: VHOG:0000118 xref: Wikipedia:Lateral_plate_mesoderm xref: XAO:0000311 xref: ZFA:0000121 is_a: UBERON:0002050 ! embryonic structure is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue relationship: BFO:0000050 UBERON:0000926 {source="EHDAA2", source="VHOG"} ! part of mesoderm relationship: RO:0002160 NCBITaxon:33213 ! only in taxon Bilateria relationship: RO:0002221 UBERON:0003887 ! surrounds intraembryonic coelom property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png" xsd:anyURI [Term] id: UBERON:0003082 name: myotome namespace: uberon def: "A transitional population of migrating mesenchymal cells that derive from somites and that will become muscle cells." [AEO:0001018] xref: AAO:0011067 xref: AEO:0001018 xref: BTO:0000742 xref: EHDAA2_RETIRED:0003431 xref: EHDAA:1721 xref: EHDAA:1727 xref: EHDAA:1733 xref: EHDAA:1739 xref: EMAPA:32841 xref: FMA:295658 xref: NCIT:C34214 xref: SCTID:344535001 xref: TAO:0001056 xref: UMLS:C1513802 {source="ncithesaurus:Myotome_Region"} xref: VHOG:0001244 xref: Wikipedia:Myotome xref: XAO:0000315 xref: ZFA:0001056 is_a: UBERON:0017650 {source="AEO"} ! developing mesenchymal structure relationship: RO:0002202 UBERON:0004290 {source="EHDAA2-abduced"} ! develops from dermomyotome relationship: RO:0002433 UBERON:0001630 ! contributes to morphology of muscle organ property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/9/96/Gray65.png" xsd:anyURI [Term] id: UBERON:0003083 name: trunk neural crest namespace: uberon def: "Trunk portion of the neural crest. The trunk neural crest lies between the vagal and sacral neural crest and gives rise to two groups of cells. One group migrates dorsolateral and populates the skin, forming pigment cells and the other migrates ventrolateral through the anterior sclerotome to become the epinephrine-producing cells of the adrenal gland and the neurons of the sympathetic nervous system. Some cells remain in the sclerotome to form the dorsal root ganglia [Wikipedia]." [ISBN:0815318960, Wikipedia:Trunk_neural_crest] xref: AAO:0010582 xref: EFO:0003605 xref: EHDAA2:0001901 xref: TAO:0001024 xref: VHOG:0000062 xref: Wikipedia:Trunk_neural_crest xref: XAO:0000319 xref: ZFA:0001024 is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0010314 ! structure with developmental contribution from neural crest relationship: BFO:0000050 UBERON:0002342 ! part of neural crest relationship: BFO:0000051 CL:0000011 {source="ZFA"} ! has part migratory trunk neural crest cell [Term] id: UBERON:0003084 name: heart primordium namespace: uberon def: "Bilateral groups of cells consisting of three rows: one row of endocardial precursors medially and two rows of myocardical precursors laterally. The two populations fuse at the midline to form the heart rudiment or cone." [ZFIN:curator] xref: AAO:0011044 xref: BTO:0001887 xref: NCIT:C34276 xref: TAO:0000028 xref: UMLS:C1514450 {source="ncithesaurus:Primordium_of_the_Heart"} xref: XAO:0000336 xref: ZFA:0000028 is_a: UBERON:0001048 {source="Obol"} ! primordium relationship: BFO:0000050 UBERON:0004535 {source="ZFA"} ! part of cardiovascular system relationship: RO:0002202 UBERON:0003081 {source="ZFA"} ! develops from lateral plate mesoderm relationship: RO:0002202 UBERON:0004140 ! develops from primary heart field relationship: RO:0002202 UBERON:0007005 {source="XAO"} ! develops from cardiogenic splanchnic mesoderm [Term] id: UBERON:0003086 name: caudal artery namespace: uberon def: "Extension of the dorsal aorta in the tail." [Wikipedia:Caudal_artery, ZFIN:curator] xref: AAO:0011023 xref: EFO:0003472 xref: TAO:0000011 xref: VHOG:0000123 xref: Wikipedia:Caudal_artery xref: XAO:0000364 xref: ZFA:0000011 is_a: UBERON:0001637 ! artery is_a: UBERON:0003524 ! tail blood vessel intersection_of: UBERON:0001637 ! artery intersection_of: BFO:0000050 UBERON:0007812 ! part of post-anal tail intersection_of: RO:0002252 UBERON:0005805 ! connecting branch of dorsal aorta relationship: BFO:0000050 RO:0002577 ! part of system relationship: BFO:0000050 UBERON:2001073 ! part of axial vasculature relationship: RO:0002252 UBERON:0005805 ! connecting branch of dorsal aorta [Term] id: UBERON:0003089 name: sclerotome namespace: uberon def: "Ventral somitic compartment that is a precursor of the axial skeleton[XAO]. Sclerotomes eventually differentiate into the vertebrae and most of the skull. The caudal (posterior) half of one sclerotome fuses with the rostral (anterior) half of the adjacent one to form each vertebra. From their initial location within the somite, the sclerotome cells migrate medially towards the notochord. These cells meet the sclerotome cells from the other side to form the vertebral body. From this vertebral body, sclerotome cells move dorsally and surround the developing spinal cord, forming the vertebral arch[WP]." [https://github.com/obophenotype/uberon/issues/316, Wikipedia:Sclerotome, XB:curator] xref: AAO:0010571 xref: AEO:0000212 xref: EHDAA2:0003439 xref: EMAPA:31159 xref: FMA:295652 xref: NCIT:C34287 xref: TAO:0001080 xref: UMLS:C0183176 {source="ncithesaurus:Sclerotome"} xref: VHOG:0000680 xref: Wikipedia:Sclerotome xref: XAO:0000397 xref: ZFA:0001080 is_a: UBERON:0005856 {source="EHDAA2"} ! developing mesenchymal condensation is_a: UBERON:0007530 {source="EHDAA2"} ! migrating mesenchyme population relationship: RO:0002160 NCBITaxon:7742 {source="VHOG:0000680"} ! only in taxon Vertebrata relationship: RO:0002202 UBERON:0002329 {source="ZFA"} ! develops from somite property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/9/96/Gray65.png" xsd:anyURI [Term] id: UBERON:0003099 name: cranial neural crest namespace: uberon def: "Neural crest cells (NCCs) originating in the anterior part of the developing embryo and residing between the mid-diencephalon and the forming hindbrain; cranial NCCs migrate dorsolaterally to form the craniofacial mesenchyme that differentiates into various craniofacial cartilages and bones, cranial neurons, glia, and connective tissues of the face; these cells enter the pharyngeal pouches and arches where they give rise to thymic cells, bones of the middle ear and jaw (mandible), and the odontoblasts of the tooth primordia; like their counterparts in the trunk, cranial NCCs also contribute to the developing peripheral nervous system, along with the pigmented cell (i.e. melanocyte) lineage." [MGI:anna] synonym: "cephalic neural crest" EXACT [EMAPA:16091] synonym: "cranial NCC population" EXACT [] synonym: "head NCC population" EXACT [] xref: AAO:0010580 xref: EFO:0003645 xref: EHDAA2:0004420 xref: EMAPA:16091 xref: TAO:0001194 xref: VHOG:0000063 xref: Wikipedia:Cranial_neural_crest xref: XAO:0001001 xref: ZFA:0001194 is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0010314 ! structure with developmental contribution from neural crest relationship: BFO:0000050 UBERON:0002342 ! part of neural crest relationship: BFO:0000051 CL:0000008 ! has part migratory cranial neural crest cell [Term] id: UBERON:0003100 name: female organism namespace: uberon def: "Gonochoristic organism that can produce female gametes." [CARO:0000028] xref: AAO:0010030 xref: BILA:0000028 xref: CARO:0000028 xref: FMA:67812 xref: HAO:0000028 xref: SCTID:362608006 xref: TAO:0000303 xref: TGMA:0001839 xref: XAO:0003005 xref: ZFA:0000303 is_a: UBERON:0000468 ! multicellular organism disjoint_from: UBERON:0003101 ! male organism [Term] id: UBERON:0003101 name: male organism namespace: uberon def: "Gonochoristic organism that can produce male gametes." [CARO:0000027] xref: AAO:0010033 xref: BILA:0000027 xref: CARO:0000027 xref: FMA:67811 xref: HAO:0000027 xref: SCTID:362609003 xref: TAO:0000242 xref: TGMA:0001838 xref: WBbt:0007850 xref: XAO:0003006 xref: ZFA:0000242 is_a: UBERON:0000468 ! multicellular organism [Term] id: UBERON:0003102 name: surface structure namespace: uberon def: "Anatomical structure that overlaps the outer epithelial layer and is adjacent to the space surrounding the organism." [http://orcid.org/0000-0002-6601-2165, https://github.com/obophenotype/uberon/issues/24] synonym: "anatomical surface feature" EXACT [EHDAA2:0003010] xref: AAO:0010337 xref: AEO_RETIRED:0000010 xref: EHDAA2_RETIRED:0003010 xref: galen:SurfaceRegion xref: TAO:0000292 xref: VSAO:0000001 xref: Wikipedia:Surface_structure xref: XAO:0003028 xref: ZFA:0000292 is_a: UBERON:0000061 ! anatomical structure relationship: RO:0002220 UBERON:0013514 ! adjacent to space surrounding organism property_value: x_1.1:contributor https://github.com/cmungall property_value: x_1.1:contributor https://github.com/wdahdul [Term] id: UBERON:0003103 name: compound organ namespace: uberon def: "Anatomical structure that has as its parts two or more multi-tissue structures of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona fide boundaries from other distinct anatomical structures of different types." [CARO:0000024] xref: AAO:0010015 xref: AEO:0000024 xref: BILA:0000024 xref: CARO:0000024 xref: EHDAA2:0003024 xref: HAO:0000024 xref: TADS:0000598 xref: TAO:0000496 xref: TGMA:0001837 xref: VHOG:0001723 xref: XAO:0003041 xref: ZFA:0000496 is_a: UBERON:0000062 ! organ property_value: IAO:0000232 "this class was introduced for consistency with CARO. However, in this ontology we typically classify organs directly under 'organ' rather than subdividing into compound and simple organs" xsd:string [Term] id: UBERON:0003104 name: mesenchyme namespace: uberon def: "Portion of tissue composed of mesenchymal cells (motile cells that develop from epthelia via an epithelial to mesenchymal transition) and surrounding extracellular material. Mesenchyme has different embryological origins in different metazoan taxa - in many invertebrates it derives in whole or part from ectoderm. In vertebrates it derives largely from mesoderm, and sometimes the terms are used interchangeably, e.g. lateral plate mesoderm/mesenchyme." [https://archive.org/details/invertebratesnde00brus/page/n240/mode/2up, https://en.wikipedia.org/wiki/Mesenchyme, https://github.com/obophenotype/uberon/issues/1641] synonym: "mesenchymal tissue" EXACT [] synonym: "mesenchyme tissue" EXACT [] synonym: "portion of mesenchymal tissue" EXACT [] synonym: "portion of mesenchyme tissue" EXACT [] xref: AAO:0010427 xref: AEO:0000145 xref: BTO:0001393 xref: CALOHA:TS-0620 xref: EHDAA2:0003145 xref: EV:0100007 xref: NCIT:C13301 xref: TAO:0000393 xref: UMLS:C0162415 {source="ncithesaurus:Mesenchyme"} xref: VHOG:0000170 xref: Wikipedia:Mesenchyme xref: XAO:0003046 xref: ZFA:0000393 is_a: UBERON:0000479 ! tissue intersection_of: UBERON:0000479 ! tissue intersection_of: RO:0002473 CL:0008019 ! composed primarily of mesenchymal cell relationship: RO:0002160 NCBITaxon:6072 ! only in taxon Eumetazoa relationship: RO:0002254 UBERON:0000926 {gci_filler="NCBITaxon:7711", gci_relation="BFO:0000050"} ! has developmental contribution from mesoderm relationship: RO:0002328 GO:0032502 ! functionally related to developmental process relationship: RO:0002473 CL:0008019 ! composed primarily of mesenchymal cell property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/f/f4/Mesenchymal_Stem_Cell.jpg" xsd:anyURI [Term] id: UBERON:0003112 name: olfactory region namespace: uberon def: "Anatomical cluster that is located in the anterior region of the cranium and provides structural support for the olfactory organ." [TAO:0000351] xref: AAO:0010206 xref: EFO:0003525 xref: NCIT:C98765 xref: TAO:0000351 xref: XAO:0003172 xref: ZFA:0000351 is_a: UBERON:0034921 ! multi organ part structure relationship: BFO:0000050 UBERON:0001703 ! part of neurocranium relationship: BFO:0000050 UBERON:0002241 ! part of chondrocranium [Term] id: UBERON:0003113 name: dermatocranium namespace: uberon def: "Subdivision of skeleton that includes all dermal bones in the cranial skeleton[ZFA,modified]." [Wikipedia:Skull_roof, ZFA:0000863] synonym: "dendrocranium" EXACT [TAO:0000863] synonym: "exocranium" EXACT [UBERONREF:0000007] xref: AAO:0010154 xref: TAO:0000863 xref: VHOG:0001665 xref: Wikipedia:Skull_roof xref: XAO:0003169 xref: ZFA:0000863 is_a: UBERON:0011159 ! primary subdivision of cranial skeletal system relationship: BFO:0000050 UBERON:0010364 ! part of dermal skeleton relationship: RO:0002160 NCBITaxon:7742 ! only in taxon Vertebrata [Term] id: UBERON:0003115 name: pharyngeal arch 4 namespace: uberon def: "Contributes to development of the cartilage of the larynx, laryngeal, pharyngeal, and soft palate muscles, superior parathyroid gland, and C-cells of the thymus." [MP:0006340] synonym: "4th pharyngeal arch" EXACT [] synonym: "4th visceral arch" EXACT [] synonym: "fourth pharyngeal arch" EXACT [] synonym: "visceral arch 4" EXACT [] xref: AAO:0010366 xref: EHDAA2:0000086 xref: EHDAA:1663 xref: EMAPA:16760 xref: FMA:293035 xref: SCTID:308770007 xref: TAO:0001599 xref: VHOG:0000299 xref: XAO:0000449 xref: ZFA:0001607 is_a: UBERON:0002539 ! pharyngeal arch [Term] id: UBERON:0003117 name: pharyngeal arch 6 namespace: uberon def: "The 6th pharyngeal arch. contributes to the development of the sternocleidomastoid and trapezius muscles." [MP:0006347] synonym: "6th arch" EXACT [EHDAA2:0004075] synonym: "gill arch 4" EXACT [ZFA:0001609] synonym: "sixth branchial arch" EXACT [] synonym: "visceral arch 6" EXACT [ZFA:0001609] xref: AAO:0010368 xref: EHDAA2:0004075 xref: EMAPA:32766 xref: FMA:293047 xref: SCTID:308772004 xref: TAO:0001601 xref: VHOG:0001205 xref: XAO:0000453 xref: ZFA:0001609 is_a: UBERON:0002539 ! pharyngeal arch [Term] id: UBERON:0003118 name: pharyngeal arch artery 1 namespace: uberon def: "The vessels formed within the first pair of branchial arches in embryogenesis." [MP:0010355] synonym: "1st arch artery" EXACT [EMAPA:16685] synonym: "AA1" EXACT [ZFA:0005005] synonym: "aortic arch 1" EXACT [ZFA:0005005] synonym: "first aortic arch" EXACT [XAO:0000342] synonym: "first branchial arch artery" EXACT [] synonym: "mandibular aortic arch" EXACT [ZFA:0005005] xref: AAO:0010415 xref: EHDAA2:0000007 xref: EMAPA:16202 xref: EMAPA:16685 xref: SCTID:308774003 xref: TAO:0005005 xref: VHOG:0000149 xref: XAO:0000342 xref: ZFA:0005005 is_a: UBERON:0004363 ! pharyngeal arch artery intersection_of: UBERON:0004363 ! pharyngeal arch artery intersection_of: BFO:0000050 UBERON:0004362 ! part of pharyngeal arch 1 relationship: BFO:0000050 UBERON:0004362 ! part of pharyngeal arch 1 relationship: RO:0002433 UBERON:0004362 ! contributes to morphology of pharyngeal arch 1 [Term] id: UBERON:0003121 name: pharyngeal arch artery 4 namespace: uberon def: "The vessels formed within the fourth pair of branchial arches in embryogenesis." [MP:0006354] synonym: "4th arch artery" EXACT [EHDAA2:0000087] synonym: "AA4" EXACT [ZFA:0005008] synonym: "aortic arch 4" EXACT [ZFA:0005008] synonym: "fourth aortic arch" EXACT [XAO:0000355] synonym: "fourth branchial arch artery" EXACT [] xref: AAO:0010420 xref: EHDAA2:0000087 xref: EMAPA:17004 xref: SCTID:308777005 xref: TAO:0005008 xref: Wikipedia:Aortic_arches#Arch_4 xref: XAO:0000355 xref: ZFA:0005008 is_a: UBERON:0004363 ! pharyngeal arch artery intersection_of: UBERON:0004363 ! pharyngeal arch artery intersection_of: BFO:0000050 UBERON:0003115 ! part of pharyngeal arch 4 relationship: BFO:0000050 UBERON:0003115 ! part of pharyngeal arch 4 [Term] id: UBERON:0003123 name: pharyngeal arch artery 6 namespace: uberon def: "The vessels formed within the sixth pair of branchial arches in embryogenesis." [MP:0006355] synonym: "6th arch artery" EXACT [EMAPA:17005] synonym: "AA6" EXACT [ZFA:0005016] synonym: "aortic arch 6" EXACT [ZFA:0005016] synonym: "sixth aortic arch" EXACT [XAO:0000353] synonym: "sixth branchial arch artery" EXACT [] xref: AAO:0010422 xref: EHDAA2:0000102 xref: EMAPA:17005 xref: SCTID:308779008 xref: TAO:0005016 xref: VHOG:0000144 xref: Wikipedia:Aortic_arches#Arch_6 xref: XAO:0000353 xref: ZFA:0005016 is_a: UBERON:0004363 ! pharyngeal arch artery intersection_of: UBERON:0004363 ! pharyngeal arch artery intersection_of: BFO:0000050 UBERON:0003117 ! part of pharyngeal arch 6 relationship: BFO:0000050 UBERON:0003117 ! part of pharyngeal arch 6 [Term] id: UBERON:0003124 name: chorion membrane namespace: uberon def: "The outermost extraembryonic membrane of amniotes." [http://orcid.org/0000-0002-6601-2165, https://github.com/geneontology/go-ontology/issues/22603, MESH:A10.615.284.473, MP:0002836] synonym: "chorion" EXACT [] synonym: "chorion (vertebrates)" EXACT [] synonym: "embryonic chorion" EXACT [] synonym: "fetal chorion" EXACT [] synonym: "uterine chorion" EXACT [http://orcid.org/0000-0002-6601-2165, ZFIN:curator] xref: BTO:0000252 xref: CALOHA:TS-0144 xref: EFO:0002780 xref: EHDAA2:0000245 xref: EHDAA:150 xref: EMAPA:16112 xref: EV:0100121 xref: FMA:80224 xref: GAID:1299 xref: MESH:D002823 xref: NCIT:C34122 xref: NCIT:C34124 xref: UMLS:C0008503 {source="ncithesaurus:Chorion"} xref: UMLS:C1516505 {source="ncithesaurus:Chorionic_Sac"} xref: VHOG:0000200 xref: Wikipedia:Chorion is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005631 ! extraembryonic membrane relationship: BFO:0000051 UBERON:0003265 ! has part chorionic mesenchyme relationship: BFO:0000051 UBERON:0003374 ! has part chorionic ectoderm relationship: RO:0002160 NCBITaxon:32524 {source="Hymans"} ! only in taxon Amniota relationship: RO:0002202 UBERON:0005971 {source="ISBN:0073040584"} ! develops from amniotic fold relationship: RO:0002220 UBERON:0000922 ! adjacent to embryo property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/5/51/Gray24.png" xsd:anyURI [Term] id: UBERON:0003128 name: cranium namespace: uberon def: "Upper portion of the skull that excludes the mandible (when present in the organism)." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Cranium_(anatomy)] synonym: "bones of cranium" EXACT [FMA:71325] synonym: "set of bones of cranium" EXACT [FMA:71325] synonym: "skull minus mandible" EXACT [] synonym: "upper part of skull" EXACT [] xref: BTO:0001328 xref: EFO:0000831 xref: EHDAA:6029 xref: EMAPA:17680 xref: FMA:71325 xref: MA:0000316 xref: MAT:0000340 xref: MIAA:0000340 xref: SCTID:181889008 xref: VHOG:0000334 xref: Wikipedia:Cranium_(anatomy) is_a: UBERON:0000075 {source="FMA-inferred"} ! subdivision of skeletal system [Term] id: UBERON:0003129 name: skull namespace: uberon def: "Anatomical structure that is part of the head consisting entirely of cranium and mandible[WP]." [http://sourceforge.net/tracker/?func=detail&aid=2962656&group_id=76834&atid=1205376, PMID:11523816, Wikipedia:Skull] xref: BTO:0001295 xref: CALOHA:TS-2344 xref: EHDAA2:0000325 xref: EMAPA:17680 xref: FMA:46565 xref: GAID:82 xref: galen:Skull xref: MESH:D012886 xref: NCIT:C12789 xref: SCTID:110530005 xref: UMLS:C0037303 {source="ncithesaurus:Skull"} xref: Wikipedia:Skull xref: WikipediaCategory:Skull is_a: UBERON:0000075 {source="FMA"} ! subdivision of skeletal system is_a: UBERON:0010314 ! structure with developmental contribution from neural crest relationship: BFO:0000050 UBERON:0000033 ! part of head relationship: BFO:0000050 UBERON:0010323 ! part of cranial skeletal system relationship: BFO:0000051 UBERON:0003128 ! has part cranium relationship: BFO:0000051 UBERON:0003278 ! has part skeleton of lower jaw relationship: RO:0002160 NCBITaxon:89593 ! only in taxon Craniata [Term] id: UBERON:0003133 name: reproductive organ namespace: uberon def: "An organ involved in reproduction." [UBERON:xp] synonym: "genital organ" EXACT [] synonym: "reproductive system organ" EXACT [] synonym: "sex organ" EXACT [] xref: EMAPA:17381 xref: EMAPA:37731 {source="MA:th"} xref: MA:0001752 xref: MESH:D005835 xref: NCIT:C25177 xref: SCTID:128181006 xref: TGMA:0000591 xref: UMLS:C0017420 {source="ncithesaurus:Genitalia"} xref: WBbt:0008422 is_a: UBERON:0000062 ! organ is_a: UBERON:0005156 ! reproductive structure intersection_of: UBERON:0000062 ! organ intersection_of: RO:0002216 GO:0000003 ! capable of part of reproduction relationship: RO:0002216 GO:0000003 ! capable of part of reproduction [Term] id: UBERON:0003134 name: female reproductive organ namespace: uberon def: "A female organ involved in reproduction." [UBERON:xp] synonym: "female organism reproductive organ" EXACT [OBOL:automatic] synonym: "female organism reproductive structure" EXACT [OBOL:automatic] synonym: "female organism reproductive system organ" EXACT [OBOL:automatic] synonym: "female organism sex organ" EXACT [OBOL:automatic] synonym: "female reproductive gland/organ" EXACT [MA:0000544] synonym: "female reproductive system organ" EXACT [] synonym: "female sex organ" EXACT [] synonym: "reproductive organ of female organism" EXACT [OBOL:automatic] synonym: "reproductive structure of female organism" EXACT [OBOL:automatic] synonym: "reproductive system organ of female organism" EXACT [OBOL:automatic] synonym: "sex organ of female organism" EXACT [OBOL:automatic] xref: EMAPA:28540 xref: MA:0000544 is_a: UBERON:0003133 ! reproductive organ intersection_of: UBERON:0003133 ! reproductive organ intersection_of: BFO:0000050 UBERON:0003100 ! part of female organism relationship: BFO:0000050 UBERON:0000474 ! part of female reproductive system [Term] id: UBERON:0003135 name: male reproductive organ namespace: uberon def: "A male organ involved in reproduction." [UBERON:xp] synonym: "male organism reproductive organ" EXACT [OBOL:automatic] synonym: "male organism reproductive structure" EXACT [OBOL:automatic] synonym: "male organism reproductive system organ" EXACT [OBOL:automatic] synonym: "male organism sex organ" EXACT [OBOL:automatic] synonym: "male reproductive gland/organ" EXACT [MA:0000545] synonym: "male reproductive system organ" EXACT [] synonym: "male sex organ" EXACT [] synonym: "reproductive organ of male organism" EXACT [OBOL:automatic] synonym: "reproductive structure of male organism" EXACT [OBOL:automatic] synonym: "reproductive system organ of male organism" EXACT [OBOL:automatic] synonym: "sex organ of male organism" EXACT [OBOL:automatic] xref: MA:0000545 xref: WBbt:0008423 is_a: UBERON:0003133 ! reproductive organ intersection_of: UBERON:0003133 ! reproductive organ intersection_of: BFO:0000050 UBERON:0003101 ! part of male organism relationship: BFO:0000050 UBERON:0000079 ! part of male reproductive system [Term] id: UBERON:0003142 name: prepupa namespace: uberon def: "An organism at the prepupal stage. The prepupal stage is a life stage interposed between the larval and the pupal stages in insects that undergo a complete metamorphosis. The start of the pre-pupal stage is marked by pupariation, and the end is marked by pupation." [GO:0035210] xref: BTO:0001110 xref: HAO:0000812 is_a: UBERON:0000468 ! multicellular organism relationship: RO:0002160 NCBITaxon:50557 ! only in taxon Insecta relationship: RO:0002495 UBERON:0002548 ! immediate transformation of larva [Term] id: UBERON:0003143 name: pupa namespace: uberon def: "An organism at the pupal stage. A life cycle stage of holometabolous insects in which the organism is a pupa and starts with the larval-pupal apolysis and ends with pupal-adult apolysis." [https://github.com/obophenotype/uberon/issues/562, Wikipedia:Pupa] xref: BTO:0001143 xref: EFO:0002684 xref: HAO:0000886 xref: Wikipedia:Pupa is_a: UBERON:0000468 ! multicellular organism intersection_of: UBERON:0000468 ! multicellular organism intersection_of: RO:0002491 UBERON:0000070 ! existence starts and ends during pupal stage relationship: RO:0000086 PATO:0001187 ! has quality pupal relationship: RO:0002160 NCBITaxon:33392 ! only in taxon Endopterygota relationship: RO:0002491 UBERON:0000070 ! existence starts and ends during pupal stage relationship: RO:0002495 UBERON:0003142 {gci_filler="NCBITaxon:7227", gci_relation="BFO:0000050"} ! immediate transformation of prepupa property_value: x_1.1:contributor https://github.com/ANiknejad property_value: x_1.1:contributor https://github.com/cmungall property_value: x_1.1:contributor https://github.com/dosumis property_value: x_1.1:contributor https://github.com/fbastian property_value: x_1.1:contributor https://github.com/mmc46 [Term] id: UBERON:0003218 name: ovary septum namespace: uberon def: "Septum that divides the ovary, the basal portion of a carpel or group of fused carpels, that encloses the ovule(s)[GO]." [GO:0080126] is_a: UBERON:0003037 ! septum intersection_of: UBERON:0003037 ! septum intersection_of: BFO:0000050 UBERON:0000992 ! part of ovary relationship: BFO:0000050 UBERON:0000992 ! part of ovary [Term] id: UBERON:0003220 name: metanephric mesenchyme namespace: uberon def: "One of the two embryological structures that give rise to the kidney (the other is the ureteric bud). The metanephric blastema mostly develops into nephrons, but can also form parts of the collecting duct system.[WP]. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros[GO]." [GO:0072075, Wikipedia:Metanephric_blastema] synonym: "metanephric blastema" EXACT [Wikipedia:Metanephric_blastema] synonym: "metanephric mesoderm" EXACT [Wikipedia:Metanephric_blastema] synonym: "metanephrogenic mesenchyme" EXACT [EHDAA:5021] synonym: "metanephros associated mesenchyme" EXACT [RETIRED_EHDAA2:0001139] xref: EHDAA2:0004062 xref: EHDAA:4041 xref: EHDAA:5021 xref: EHDAA:5915 xref: EMAPA:17375 xref: SCTID:361529008 xref: VHOG:0000540 xref: Wikipedia:Metanephric_blastema is_a: UBERON:0003918 ! kidney mesenchyme is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0006598 ! presumptive structure intersection_of: UBERON:0003104 ! mesenchyme intersection_of: RO:0002387 UBERON:0000081 ! has potential to develop into metanephros relationship: RO:0002202 UBERON:0003074 ! develops from mesonephric duct relationship: RO:0002256 UBERON:0000084 {source="ISBN:9780878932504"} ! developmentally induced by ureteric bud relationship: RO:0002387 UBERON:0000081 ! has potential to develop into metanephros [Term] id: UBERON:0003224 name: chorion syncytiotrophoblast namespace: uberon def: "An extraembryonic structure that develops_from a syncytiotrophoblast and is part of a chorion." [OBOL:automatic] xref: EHDAA2:0001973 xref: EHDAA:156 is_a: UBERON:0000478 ! extraembryonic structure intersection_of: UBERON:0000478 ! extraembryonic structure intersection_of: BFO:0000050 UBERON:0003124 ! part of chorion membrane intersection_of: RO:0002202 UBERON:0000371 ! develops from syncytiotrophoblast relationship: BFO:0000050 UBERON:0003124 {source="EHDAA2"} ! part of chorion membrane relationship: RO:0002202 UBERON:0000371 ! develops from syncytiotrophoblast [Term] id: UBERON:0003235 name: epithelium of upper jaw namespace: uberon def: "An epithelium that is part of a upper jaw [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of palatoquadrate arch" EXACT [OBOL:automatic] synonym: "epithelial tissue of upper jaw" EXACT [OBOL:automatic] synonym: "epithelium of palatoquadrate arch" EXACT [OBOL:automatic] synonym: "palatoquadrate arch epithelial tissue" EXACT [OBOL:automatic] synonym: "palatoquadrate arch epithelium" EXACT [OBOL:automatic] synonym: "upper jaw epithelial tissue" EXACT [OBOL:automatic] synonym: "upper jaw epithelium" EXACT [OBOL:automatic] xref: EHDAA2:0002119 xref: EHDAA:8027 xref: EMAPA:17943 xref: EMAPA:18971 is_a: UBERON:0035037 ! jaw epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: BFO:0000050 UBERON:0001709 ! part of upper jaw region relationship: BFO:0000050 UBERON:0001709 ! part of upper jaw region [Term] id: UBERON:0003236 name: epithelium of lower jaw namespace: uberon def: "An epithelium that is part of a lower jaw [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of lower jaw" EXACT [OBOL:automatic] synonym: "epithelial tissue of ventral mandibular arch" EXACT [OBOL:automatic] synonym: "epithelium of ventral mandibular arch" EXACT [OBOL:automatic] synonym: "lower jaw epithelial tissue" EXACT [OBOL:automatic] synonym: "lower jaw epithelium" EXACT [OBOL:automatic] synonym: "ventral mandibular arch epithelial tissue" EXACT [OBOL:automatic] synonym: "ventral mandibular arch epithelium" EXACT [OBOL:automatic] xref: EHDAA2:0001019 xref: EHDAA:7999 xref: EMAPA:35516 xref: VHOG:0000802 is_a: UBERON:0035037 ! jaw epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: BFO:0000050 UBERON:0001710 ! part of lower jaw region relationship: BFO:0000050 UBERON:0001710 ! part of lower jaw region [Term] id: UBERON:0003257 name: yolk sac endoderm namespace: uberon def: "The portion of the yolk sac that is derived from endoderm and lines the yolk sac." [UBERON:cjm] xref: EHDAA2:0002215 xref: EHDAA:166 xref: EMAPA:16086 xref: VHOG:0000626 is_a: UBERON:0000478 {source="EHDAA2"} ! extraembryonic structure is_a: UBERON:0005292 ! extraembryonic tissue is_a: UBERON:0005911 ! endo-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: RO:0002007 UBERON:0001040 ! bounding layer of yolk sac intersection_of: RO:0002202 UBERON:0000925 ! develops from endoderm relationship: RO:0002007 UBERON:0001040 ! bounding layer of yolk sac [Term] id: UBERON:0003258 name: endoderm of foregut namespace: uberon def: "An endoderm that is part of a foregut [Automatically generated definition]." [OBOL:automatic] synonym: "foregut endoderm" EXACT [OBOL:automatic] xref: EHDAA2:0004568 xref: EHDAA:524 is_a: UBERON:0000490 ! unilaminar epithelium is_a: UBERON:0005911 ! endo-epithelium is_a: UBERON:0015833 ! foregut epithelium intersection_of: UBERON:0000490 ! unilaminar epithelium intersection_of: BFO:0000050 UBERON:0001041 ! part of foregut intersection_of: RO:0002202 UBERON:0000925 ! develops from endoderm [Term] id: UBERON:0003259 name: endoderm of midgut namespace: uberon def: "An endoderm that is part of a midgut [Automatically generated definition]." [OBOL:automatic] synonym: "midgut endoderm" EXACT [OBOL:automatic] xref: EHDAA:987 xref: EMAPA:16257 xref: RETIRED_EHDAA2:0001194 xref: VHOG:0001080 is_a: UBERON:0000490 ! unilaminar epithelium is_a: UBERON:0003352 ! epithelium of midgut is_a: UBERON:0005911 ! endo-epithelium intersection_of: UBERON:0000490 ! unilaminar epithelium intersection_of: BFO:0000050 UBERON:0001045 ! part of midgut intersection_of: RO:0002202 UBERON:0000925 ! develops from endoderm [Term] id: UBERON:0003260 name: endoderm of hindgut namespace: uberon def: "An endoderm that is part of a hindgut [Automatically generated definition]." [OBOL:automatic] synonym: "hindgut endoderm" EXACT [OBOL:automatic] xref: EHDAA:979 xref: RETIRED_EHDAA2:0000781 is_a: UBERON:0000490 ! unilaminar epithelium is_a: UBERON:0003353 ! epithelium of hindgut is_a: UBERON:0005911 ! endo-epithelium intersection_of: UBERON:0000490 ! unilaminar epithelium intersection_of: BFO:0000050 UBERON:0001046 ! part of hindgut intersection_of: RO:0002202 UBERON:0000925 ! develops from endoderm [Term] id: UBERON:0003265 name: chorionic mesenchyme namespace: uberon def: "A mesenchyme that is part of a chorion." [OBOL:automatic] synonym: "chorion mesenchyme" EXACT [OBOL:automatic] synonym: "chorion mesoderm" EXACT [RETIRED_EHDAA2:0000247] synonym: "chorionic mesenchyme" EXACT [EHDAA2:0003245] synonym: "mesenchyme of chorion" EXACT [] synonym: "mesenchyme of chorion (vertebrates)" EXACT [OBOL:automatic] xref: EHDAA2:0003245 xref: EHDAA:154 xref: EMAPA:16114 xref: EMAPA:16266 xref: RETIRED_EHDAA2:0000247 xref: VHOG:0000620 is_a: UBERON:0000478 {source="EHDAA2"} ! extraembryonic structure is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue is_a: UBERON:0010333 ! extraembryonic membrane mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: BFO:0000050 UBERON:0003124 ! part of chorion membrane relationship: BFO:0000050 UBERON:0003124 ! part of chorion membrane relationship: RO:0002202 UBERON:0004871 {source="ISBN:0073040584"} ! develops from somatic layer of lateral plate mesoderm [Term] id: UBERON:0003269 name: skeletal muscle tissue of eye namespace: uberon def: "A portion of skeletal muscle tissue that is part of a eye [Automatically generated definition]." [OBOL:automatic] synonym: "eye skeletal muscle" EXACT [OBOL:automatic] synonym: "eye skeletal muscle tissue" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue of eye" EXACT [OBOL:automatic] xref: EHDAA2:0000486 xref: EHDAA:2923 xref: EMAPA:17844 is_a: UBERON:0001134 ! skeletal muscle tissue is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: BFO:0000050 UBERON:0000019 ! part of camera-type eye relationship: BFO:0000050 UBERON:0000019 ! part of camera-type eye [Term] id: UBERON:0003277 name: skeleton of upper jaw namespace: uberon def: "A subdivision of the skeleton that corresponds to the upper part of the mouth. The lower jaw skeleton includes the following elements, when present: upper jaw teeth, the maxilla and other lower jaw bones." [http://orcid.org/0000-0002-6601-2165] synonym: "upper jaw skeleton" EXACT [] xref: AAO:0000622 xref: EHDAA2:0002128 xref: EHDAA:8041 xref: EMAPA:17927 xref: FMA:54397 xref: MA:0001908 xref: VHOG:0000429 xref: XAO:0003087 is_a: UBERON:0010313 ! neural crest-derived structure is_a: UBERON:0010912 ! subdivision of skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: RO:0002576 UBERON:0001709 ! skeleton of upper jaw region relationship: BFO:0000050 UBERON:0001708 ! part of jaw skeleton relationship: RO:0002576 UBERON:0001709 ! skeleton of upper jaw region [Term] id: UBERON:0003278 name: skeleton of lower jaw namespace: uberon def: "A subdivision of the skeleton that corresponds to the lower part of the mouth. The lower jaw skeleton includes the following elements, when present: lower jaw teeth, the mandible and other lower jaw bones, and Meckel's cartilage." [http://orcid.org/0000-0002-6601-2165] synonym: "lower jaw skeleton" EXACT [AAO:0000274] xref: AAO:0000274 xref: EHDAA2:0004606 xref: EHDAA:8005 xref: EMAPA:17906 xref: EMAPA:17910 xref: FMA:54398 xref: MA:0001906 xref: TAO:0001273 xref: VHOG:0000428 xref: XAO:0003084 xref: ZFA:0001273 is_a: UBERON:0010313 ! neural crest-derived structure is_a: UBERON:0010912 ! subdivision of skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: RO:0002576 UBERON:0001710 ! skeleton of lower jaw region relationship: BFO:0000050 UBERON:0001708 ! part of jaw skeleton relationship: RO:0002131 UBERON:0008895 {source="VHOG-modified"} ! overlaps splanchnocranium relationship: RO:0002576 UBERON:0001710 ! skeleton of lower jaw region [Term] id: UBERON:0003281 name: mesentery of stomach namespace: uberon def: "The portion of the primitive mesentery that encloses the stomach; from its dorsal sheet, the greater omentum develops, and from its ventral sheet, the lesser omentum." [http://medical-dictionary.thefreedictionary.com/mesogastrium] synonym: "mesentery of ventriculus" EXACT [OBOL:automatic] synonym: "mesogaster" EXACT [http://medical-dictionary.thefreedictionary.com/mesogastrium] synonym: "mesogastium" EXACT [MA:0001617] synonym: "mesogastrium" EXACT [http://www.vivo.colostate.edu/hbooks/pathphys/misc_topics/peritoneum.html] synonym: "stomach mesentery" EXACT [Obol:obol] synonym: "ventriculus mesentery" EXACT [OBOL:automatic] xref: EHDAA2:0001922 xref: EHDAA:2999 xref: EMAPA:17024 xref: MA:0001617 xref: SCTID:261623000 xref: VHOG:0000358 is_a: UBERON:0004854 {source="MA"} ! gastrointestinal system mesentery intersection_of: UBERON:0002095 ! mesentery intersection_of: BFO:0000050 UBERON:0000945 ! part of stomach relationship: BFO:0000050 UBERON:0000945 {source="MA"} ! part of stomach relationship: RO:0002433 UBERON:0000945 ! contributes to morphology of stomach [Term] id: UBERON:0003282 name: mesentery of heart namespace: uberon def: "A mesentery that surrounds the heart." [MA:th] synonym: "heart mesentery" EXACT [OBOL:automatic] xref: EHDAA:432 xref: EMAPA:16212 xref: RETIRED_EHDAA2:0000739 xref: VHOG:0000353 is_a: UBERON:0002095 ! mesentery intersection_of: UBERON:0002095 ! mesentery intersection_of: BFO:0000050 UBERON:0000948 ! part of heart relationship: BFO:0000050 UBERON:0000948 ! part of heart [Term] id: UBERON:0003283 name: mesentery of oesophagus namespace: uberon def: "A mesentery that is part of a esophagus [Automatically generated definition]." [OBOL:automatic] synonym: "esophagus mesentery" EXACT [MA:0001569] synonym: "gullet mesentery" EXACT [OBOL:automatic] synonym: "mesentery of esophagus" EXACT [OBOL:automatic] synonym: "mesentery of gullet" EXACT [OBOL:automatic] synonym: "meso-esophagus" EXACT [] synonym: "oesophagus mesentery" EXACT [VHOG:0000415] xref: EHDAA2:0001288 xref: EHDAA:2943 xref: EMAPA:16836 xref: MA:0001569 xref: VHOG:0000415 is_a: UBERON:0001975 ! serosa of esophagus is_a: UBERON:0002095 ! mesentery intersection_of: UBERON:0002095 ! mesentery intersection_of: BFO:0000050 UBERON:0001043 ! part of esophagus [Term] id: UBERON:0003284 name: mesentery of midgut namespace: uberon def: "A mesentery that is part of a midgut [Automatically generated definition]." [OBOL:automatic] synonym: "midgut mesentery" EXACT [OBOL:automatic] xref: EHDAA2:0001202 xref: EHDAA:3031 xref: EMAPA:16721 xref: EMAPA:17039 xref: EMAPA:17197 xref: VHOG:0000413 is_a: UBERON:0002095 ! mesentery intersection_of: UBERON:0002095 ! mesentery intersection_of: BFO:0000050 UBERON:0001045 ! part of midgut relationship: BFO:0000050 UBERON:0001045 ! part of midgut [Term] id: UBERON:0003294 name: gland of foregut namespace: uberon def: "A gland that is part of a foregut [Automatically generated definition]." [OBOL:automatic] synonym: "foregut gland" EXACT [OBOL:automatic] xref: EHDAA2:0000567 xref: EHDAA:950 xref: EMAPA:16557 xref: VHOG:0000650 is_a: UBERON:0003408 ! gland of digestive tract intersection_of: UBERON:0002530 ! gland intersection_of: BFO:0000050 UBERON:0001041 ! part of foregut relationship: BFO:0000050 UBERON:0001041 ! part of foregut [Term] id: UBERON:0003295 name: pharyngeal gland namespace: uberon def: "Racemose mucous glands beneath the mucous membrane of the pharynx." [http://www.biology-online.org/dictionary/] synonym: "pharynx gland" EXACT [EHDAA2:0001461] xref: BTO:0004849 xref: EHDAA2:0001461 xref: EHDAA:2967 xref: FMA:55075 is_a: UBERON:0003408 ! gland of digestive tract is_a: UBERON:0036225 ! respiratory system gland intersection_of: UBERON:0002530 ! gland intersection_of: BFO:0000050 UBERON:0001042 ! part of chordate pharynx relationship: BFO:0000050 UBERON:0001042 {source="BTO"} ! part of chordate pharynx [Term] id: UBERON:0003297 name: gland of integumental system namespace: uberon def: "A gland that is part of a integumental system [Automatically generated definition]." [OBOL:automatic] synonym: "integumental gland" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "integumental system gland" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "integumentary gland" EXACT [http://orcid.org/0000-0002-6601-2165] xref: EHDAA2:0000837 xref: EHDAA:6522 xref: EMAPA:17758 xref: MA:0000144 xref: VHOG:0000654 is_a: UBERON:0002530 ! gland intersection_of: UBERON:0002530 ! gland intersection_of: BFO:0000050 UBERON:0002416 ! part of integumental system relationship: BFO:0000050 UBERON:0002416 ! part of integumental system [Term] id: UBERON:0003304 name: mesoderm blood island namespace: uberon def: "A blood island that is part of a mesoderm." [OBOL:automatic] xref: EHDAA2:0003241 xref: EHDAA:170 xref: EMAPA:16115 is_a: UBERON:0003061 ! blood island is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0007503 {source="EHDAA2"} ! epithelial vesicle is_a: UBERON:0012275 ! meso-epithelium intersection_of: UBERON:0003061 ! blood island intersection_of: BFO:0000050 UBERON:0000926 ! part of mesoderm relationship: BFO:0000050 UBERON:0000926 ! part of mesoderm relationship: BFO:0000050 UBERON:0007798 {source="EHDAA2"} ! part of vascular system [Term] id: UBERON:0003312 name: mesenchyme of testis namespace: uberon def: "Mesenchyme that is part of a developing testis [Automatically generated definition]." [OBOL:automatic] synonym: "testis mesenchyme" EXACT [OBOL:automatic] xref: EHDAA2:0002010 xref: EHDAA:8150 xref: EMAPA:35858 xref: VHOG:0001442 is_a: UBERON:0003855 ! gonad mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: BFO:0000050 UBERON:0000473 ! part of testis relationship: BFO:0000050 UBERON:0000473 ! part of testis [Term] id: UBERON:0003314 name: eye mesenchyme namespace: uberon def: "Mesenchyme that is part of a developing camera-type eye." [OBOL:automatic] synonym: "mesenchyme of eye" EXACT [OBOL:automatic] xref: EHDAA2:0000485 xref: EHDAA:2910 xref: EMAPA:16673 xref: VHOG:0001084 is_a: UBERON:0007213 ! mesenchyme derived from head neural crest is_a: UBERON:0009891 ! facial mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: BFO:0000050 UBERON:0000019 ! part of camera-type eye relationship: BFO:0000050 UBERON:0000019 ! part of camera-type eye relationship: RO:0002202 UBERON:0009920 {source="EHDAA2"} ! develops from optic neural crest [Term] id: UBERON:0003315 name: mesenchyme of ovary namespace: uberon def: "Mesenchyme that is part of a developing ovary [Automatically generated definition]." [OBOL:automatic] synonym: "female reproductive system gonad mesenchyme" EXACT [OBOL:automatic] synonym: "female reproductive system gonada mesenchyme" EXACT [OBOL:automatic] synonym: "gonad of female reproductive system mesenchyme" EXACT [OBOL:automatic] synonym: "gonada of female reproductive system mesenchyme" EXACT [OBOL:automatic] synonym: "mesenchyme of female reproductive system gonad" EXACT [OBOL:automatic] synonym: "mesenchyme of female reproductive system gonada" EXACT [OBOL:automatic] synonym: "mesenchyme of gonad of female reproductive system" EXACT [OBOL:automatic] synonym: "mesenchyme of gonada of female reproductive system" EXACT [OBOL:automatic] synonym: "ovary mesenchyme" EXACT [OBOL:automatic] xref: EHDAA2:0001362 xref: EHDAA:8128 xref: VHOG:0001441 is_a: UBERON:0003855 ! gonad mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: BFO:0000050 UBERON:0000992 ! part of ovary relationship: BFO:0000050 UBERON:0000992 ! part of ovary [Term] id: UBERON:0003316 name: mesenchyme of yolk sac namespace: uberon def: "The portion of the yolk sac that is derived from mesoderm and consists of mesenchyme." [UBERON:cjm] synonym: "yolk sac mesenchyme" EXACT [OBOL:automatic] xref: EHDAA2:0002216 xref: EHDAA:168 xref: EHDAA:205 xref: EMAPA:16087 xref: EMAPA:16267 xref: VHOG:0000503 xref: VHOG:0000617 is_a: UBERON:0010333 ! extraembryonic membrane mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: BFO:0000050 UBERON:0001040 ! part of yolk sac relationship: BFO:0000050 UBERON:0001040 ! part of yolk sac [Term] id: UBERON:0003323 name: mesenchyme of upper jaw namespace: uberon def: "Mesenchyme that is part of a developing upper jaw [Automatically generated definition]." [OBOL:automatic] synonym: "mesenchyme of palatoquadrate arch" EXACT [OBOL:automatic] synonym: "palatoquadrate arch mesenchyme" EXACT [OBOL:automatic] synonym: "upper jaw mesenchyme" EXACT [OBOL:automatic] xref: EHDAA2:0002124 xref: EHDAA:8031 xref: EMAPA:17929 xref: VHOG:0001099 is_a: UBERON:0009891 ! facial mesenchyme is_a: UBERON:0034995 ! jaw mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: BFO:0000050 UBERON:0001709 ! part of upper jaw region relationship: BFO:0000050 UBERON:0001709 ! part of upper jaw region relationship: RO:0002202 UBERON:0009526 {source="EHDAA2"} ! develops from maxillary process mesenchyme [Term] id: UBERON:0003324 name: mesenchyme of lower jaw namespace: uberon def: "Mesenchyme that is part of a developing lower jaw [Automatically generated definition]." [OBOL:automatic] synonym: "lower jaw mesenchyme" EXACT [OBOL:automatic] synonym: "mesenchyme of ventral mandibular arch" EXACT [OBOL:automatic] synonym: "ventral mandibular arch mesenchyme" EXACT [OBOL:automatic] xref: EHDAA2:0001024 xref: EHDAA:8003 xref: EMAPA:17916 xref: VHOG:0001069 is_a: UBERON:0034995 ! jaw mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: BFO:0000050 UBERON:0001710 ! part of lower jaw region relationship: BFO:0000050 UBERON:0001710 ! part of lower jaw region relationship: RO:0002202 UBERON:0006905 {source="EHDAA2"} ! develops from mandibular process mesenchyme [Term] id: UBERON:0003329 name: submucosa of anal canal namespace: uberon def: "A submucosa that is part of an anal canal [Automatically generated definition]." [OBOL:automatic] synonym: "anal canal submucosa" EXACT [OBOL:automatic] synonym: "anal canal viewed anatomically submucosa" EXACT [OBOL:automatic] synonym: "anal region submucosa" EXACT [OBOL:automatic] synonym: "anatomical anal canal submucosa" EXACT [OBOL:automatic] synonym: "submucosa of anal canal viewed anatomically" EXACT [OBOL:automatic] synonym: "submucosa of anal region" EXACT [OBOL:automatic] synonym: "submucosa of anatomical anal canal" EXACT [OBOL:automatic] xref: EMAPA:27217 xref: EMAPA:27227 xref: EMAPA:27535 xref: FMA:85399 xref: SCTID:7892006 is_a: UBERON:0001208 ! submucosa of large intestine is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0000009 ! submucosa intersection_of: BFO:0000050 UBERON:0000159 ! part of anal canal relationship: BFO:0000050 UBERON:0000159 ! part of anal canal [Term] id: UBERON:0003330 name: submucosa of rectum namespace: uberon def: "The submucous layer of the wall of the rectum." [BTO:0002114] synonym: "rectal submucosa" EXACT [FMA:15034] synonym: "rectum submucosa" EXACT [OBOL:automatic] xref: BTO:0002114 xref: EMAPA:27083 xref: FMA:15034 xref: SCTID:71683001 is_a: UBERON:0001208 ! submucosa of large intestine intersection_of: UBERON:0000009 ! submucosa intersection_of: BFO:0000050 UBERON:0001052 ! part of rectum relationship: BFO:0000050 UBERON:0001052 ! part of rectum [Term] id: UBERON:0003331 name: submucosa of colon namespace: uberon def: "A submucosa that is part of a colon [Automatically generated definition]." [OBOL:automatic] synonym: "colon submucosa" EXACT [OBOL:automatic] synonym: "colonic submucosa" EXACT [FMA:14985] synonym: "large bowel submucosa" EXACT [OBOL:automatic] synonym: "submucosa of large bowel" EXACT [OBOL:automatic] xref: EMAPA:27379 xref: FMA:14985 xref: MA:0003200 xref: SCTID:61647009 is_a: UBERON:0001208 ! submucosa of large intestine intersection_of: UBERON:0000009 ! submucosa intersection_of: BFO:0000050 UBERON:0001155 ! part of colon relationship: BFO:0000050 UBERON:0001155 ! part of colon [Term] id: UBERON:0003332 name: submucosa of duodenum namespace: uberon def: "A submucosa that is part of a duodenum [Automatically generated definition]." [OBOL:automatic] synonym: "doudenal submucosa" EXACT [FMA:14943] synonym: "duodenal submucosa" EXACT [FMA:14943] synonym: "duodenum submucosa" EXACT [OBOL:automatic] xref: EMAPA:27027 xref: EMAPA:27097 xref: EMAPA:27239 xref: FMA:14943 xref: MA:0003213 xref: SCTID:76519004 is_a: UBERON:0001205 ! submucosa of small intestine intersection_of: UBERON:0000009 ! submucosa intersection_of: BFO:0000050 UBERON:0002114 ! part of duodenum relationship: BFO:0000050 UBERON:0002114 ! part of duodenum [Term] id: UBERON:0003334 name: serosa of rectum namespace: uberon def: "A serous membrane that is part of a rectum [Automatically generated definition]." [OBOL:automatic] synonym: "rectal serosa" EXACT [FMA:15039] synonym: "rectum serosa" EXACT [OBOL:automatic] synonym: "rectum serous membrane" EXACT [OBOL:automatic] synonym: "serous membrane of rectum" EXACT [OBOL:automatic] synonym: "visceral peritoneum of rectum" EXACT [FMA:15039] xref: EMAPA:27087 xref: FMA:15039 is_a: UBERON:0001209 ! serosa of large intestine intersection_of: UBERON:0000042 ! serous membrane intersection_of: BFO:0000050 UBERON:0001052 ! part of rectum relationship: BFO:0000050 UBERON:0001052 ! part of rectum [Term] id: UBERON:0003335 name: serosa of colon namespace: uberon def: "A serous membrane that is part of a colon [Automatically generated definition]." [OBOL:automatic] synonym: "colon serosa" EXACT [OBOL:automatic] synonym: "colon serous membrane" EXACT [OBOL:automatic] synonym: "colonic serosa" EXACT [FMA:14990] synonym: "large bowel serosa" EXACT [OBOL:automatic] synonym: "large bowel serous membrane" EXACT [OBOL:automatic] synonym: "serosa of large bowel" EXACT [OBOL:automatic] synonym: "serous membrane of colon" EXACT [OBOL:automatic] synonym: "serous membrane of large bowel" EXACT [OBOL:automatic] synonym: "visceral peritoneum of colon" EXACT [FMA:14990] xref: EMAPA:27387 xref: FMA:14990 xref: MA:0003199 xref: SCTID:90132000 is_a: UBERON:0001209 ! serosa of large intestine intersection_of: UBERON:0000042 ! serous membrane intersection_of: BFO:0000050 UBERON:0001155 ! part of colon relationship: BFO:0000050 UBERON:0001155 ! part of colon [Term] id: UBERON:0003336 name: serosa of duodenum namespace: uberon def: "A serous membrane that is part of a duodenum [Automatically generated definition]." [OBOL:automatic] synonym: "doudenal serosa" EXACT [FMA:14948] synonym: "duodenal serosa" EXACT [FMA:14948] synonym: "duodenum serosa" EXACT [OBOL:automatic] synonym: "duodenum serous membrane" EXACT [OBOL:automatic] synonym: "serous membrane of duodenum" EXACT [OBOL:automatic] synonym: "visceral peritoneum of duodenum" EXACT [FMA:14948] xref: EMAPA:27247 xref: FMA:14948 xref: MA:0003212 xref: SCTID:1236009 is_a: UBERON:0001206 ! serosa of small intestine intersection_of: UBERON:0000042 ! serous membrane intersection_of: BFO:0000050 UBERON:0002114 ! part of duodenum relationship: BFO:0000050 UBERON:0002114 ! part of duodenum [Term] id: UBERON:0003338 name: ganglion of peripheral nervous system namespace: uberon def: "A spatially aggregated collection of nerve cell bodies in the PNS, consisting of one or more subpopulations that share cell type, chemical phenotype, and connections. (CUMBO)." [BIRNLEX:2548] synonym: "peripheral nervous system ganglion" EXACT [OBOL:automatic] xref: BIRNLEX:2548 xref: BTO:0001123 xref: EMAPA:32814 xref: MA:0001161 is_a: UBERON:0000045 ! ganglion intersection_of: UBERON:0000045 ! ganglion intersection_of: BFO:0000050 UBERON:0000010 ! part of peripheral nervous system relationship: BFO:0000050 UBERON:0000010 ! part of peripheral nervous system [Term] id: UBERON:0003339 name: ganglion of central nervous system namespace: uberon def: "A ganglion that is part of a central nervous system [Automatically generated definition]." [OBOL:automatic] synonym: "central nervous system ganglion" EXACT [OBOL:automatic] synonym: "ganglion of neuraxis" EXACT [OBOL:automatic] synonym: "neuraxis ganglion" EXACT [OBOL:automatic] xref: EHDAA2:0000227 xref: EMAPA:16658 xref: FMA:83843 is_a: UBERON:0000045 ! ganglion is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0000045 ! ganglion intersection_of: BFO:0000050 UBERON:0001017 ! part of central nervous system relationship: BFO:0000050 UBERON:0001017 ! part of central nervous system [Term] id: UBERON:0003342 name: mucosa of anal canal namespace: uberon def: "A mucosa that is part of an anal canal [Automatically generated definition]." [OBOL:automatic] synonym: "anal canal mucosa" EXACT [OBOL:automatic] synonym: "anal canal mucosa of organ" EXACT [OBOL:automatic] synonym: "anal canal mucous membrane" EXACT [OBOL:automatic] synonym: "anal canal organ mucosa" EXACT [OBOL:automatic] synonym: "anal canal viewed anatomically mucosa" EXACT [OBOL:automatic] synonym: "anal canal viewed anatomically mucosa of organ" EXACT [OBOL:automatic] synonym: "anal canal viewed anatomically mucous membrane" EXACT [OBOL:automatic] synonym: "anal canal viewed anatomically organ mucosa" EXACT [OBOL:automatic] synonym: "anal mucosa" EXACT [FMA:74654] synonym: "anal mucous membrane" EXACT [FMA:74654] synonym: "anal region mucosa" EXACT [OBOL:automatic] synonym: "anal region mucosa of organ" EXACT [OBOL:automatic] synonym: "anal region mucous membrane" EXACT [OBOL:automatic] synonym: "anal region organ mucosa" EXACT [OBOL:automatic] synonym: "anatomical anal canal mucosa" EXACT [OBOL:automatic] synonym: "anatomical anal canal mucosa of organ" EXACT [OBOL:automatic] synonym: "anatomical anal canal mucous membrane" EXACT [OBOL:automatic] synonym: "anatomical anal canal organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of anal canal viewed anatomically" EXACT [OBOL:automatic] synonym: "mucosa of anal region" EXACT [OBOL:automatic] synonym: "mucosa of anatomical anal canal" EXACT [OBOL:automatic] synonym: "mucosa of organ of anal canal" EXACT [OBOL:automatic] synonym: "mucosa of organ of anal canal viewed anatomically" EXACT [OBOL:automatic] synonym: "mucosa of organ of anal region" EXACT [OBOL:automatic] synonym: "mucosa of organ of anatomical anal canal" EXACT [OBOL:automatic] synonym: "mucous membrane of anal canal" EXACT [OBOL:automatic] synonym: "mucous membrane of anal canal viewed anatomically" EXACT [OBOL:automatic] synonym: "mucous membrane of anal region" EXACT [OBOL:automatic] synonym: "mucous membrane of anatomical anal canal" EXACT [OBOL:automatic] synonym: "organ mucosa of anal canal" EXACT [OBOL:automatic] synonym: "organ mucosa of anal canal viewed anatomically" EXACT [OBOL:automatic] synonym: "organ mucosa of anal region" EXACT [OBOL:automatic] synonym: "organ mucosa of anatomical anal canal" EXACT [OBOL:automatic] xref: EMAPA:27531 xref: FMA:74654 xref: NCIT:C60784 xref: SCTID:362170004 xref: UMLS:C0227414 {source="ncithesaurus:Anal_Mucosa"} is_a: UBERON:0001207 ! mucosa of large intestine is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0000344 ! mucosa intersection_of: BFO:0000050 UBERON:0000159 ! part of anal canal relationship: BFO:0000050 UBERON:0000159 ! part of anal canal [Term] id: UBERON:0003343 name: mucosa of oral region namespace: uberon def: "A mucosa that is part of a oral opening [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of oral opening" EXACT [OBOL:automatic] synonym: "mucosa of oral part of face" EXACT [OBOL:automatic] synonym: "mucosa of organ of oral opening" EXACT [OBOL:automatic] synonym: "mucosa of organ of oral part of face" EXACT [OBOL:automatic] synonym: "mucosa of organ of oral region" EXACT [OBOL:automatic] synonym: "mucosa of organ of subdivision of mouth" EXACT [OBOL:automatic] synonym: "mucosa of subdivision of mouth" EXACT [OBOL:automatic] synonym: "mucous membrane of oral opening" EXACT [OBOL:automatic] synonym: "mucous membrane of oral part of face" EXACT [OBOL:automatic] synonym: "mucous membrane of oral region" EXACT [OBOL:automatic] synonym: "mucous membrane of subdivision of mouth" EXACT [OBOL:automatic] synonym: "oral opening mucosa" EXACT [OBOL:automatic] synonym: "oral opening mucosa of organ" EXACT [OBOL:automatic] synonym: "oral opening mucous membrane" EXACT [OBOL:automatic] synonym: "oral opening organ mucosa" EXACT [OBOL:automatic] synonym: "oral part of face mucosa" EXACT [OBOL:automatic] synonym: "oral part of face mucosa of organ" EXACT [OBOL:automatic] synonym: "oral part of face mucous membrane" EXACT [OBOL:automatic] synonym: "oral part of face organ mucosa" EXACT [OBOL:automatic] synonym: "oral region mucosa" EXACT [OBOL:automatic] synonym: "oral region mucosa of organ" EXACT [OBOL:automatic] synonym: "oral region mucous membrane" EXACT [OBOL:automatic] synonym: "oral region organ mucosa" EXACT [OBOL:automatic] synonym: "organ mucosa of oral opening" EXACT [OBOL:automatic] synonym: "organ mucosa of oral part of face" EXACT [OBOL:automatic] synonym: "organ mucosa of oral region" EXACT [OBOL:automatic] synonym: "organ mucosa of subdivision of mouth" EXACT [OBOL:automatic] synonym: "subdivision of mouth mucosa" EXACT [OBOL:automatic] synonym: "subdivision of mouth mucosa of organ" EXACT [OBOL:automatic] synonym: "subdivision of mouth mucous membrane" EXACT [OBOL:automatic] synonym: "subdivision of mouth organ mucosa" EXACT [OBOL:automatic] xref: EMAPA:26937 xref: SCTID:362083000 is_a: UBERON:0003729 ! mouth mucosa intersection_of: UBERON:0000344 ! mucosa intersection_of: BFO:0000050 UBERON:0000166 ! part of oral opening relationship: BFO:0000050 UBERON:0000166 ! part of oral opening [Term] id: UBERON:0003346 name: mucosa of rectum namespace: uberon def: "A mucosa that is part of a rectum [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of organ of rectum" EXACT [OBOL:automatic] synonym: "mucous membrane of rectum" EXACT [OBOL:automatic] synonym: "organ mucosa of rectum" EXACT [OBOL:automatic] synonym: "rectal mucosa" EXACT [FMA:15033] synonym: "rectal mucous membrane" EXACT [FMA:15033] synonym: "rectum mucosa" EXACT [OBOL:automatic] synonym: "rectum mucosa of organ" EXACT [OBOL:automatic] synonym: "rectum mucous membrane" EXACT [OBOL:automatic] synonym: "rectum organ mucosa" EXACT [OBOL:automatic] xref: CALOHA:TS-2107 xref: EMAPA:27081 xref: FMA:15033 xref: MA:0003218 xref: SCTID:362167003 is_a: UBERON:0001207 ! mucosa of large intestine intersection_of: UBERON:0000344 ! mucosa intersection_of: BFO:0000050 UBERON:0001052 ! part of rectum relationship: BFO:0000050 UBERON:0001052 ! part of rectum [Term] id: UBERON:0003350 name: epithelium of mucosa namespace: uberon def: "A layer of epithelial cells on the surface of the mucosa." [BTO:0003752] xref: BTO:0003752 is_a: UBERON:0000483 ! epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: BFO:0000050 UBERON:0000344 ! part of mucosa relationship: BFO:0000050 UBERON:0000344 ! part of mucosa [Term] id: UBERON:0003351 name: pharyngeal epithelium namespace: uberon def: "An epithelium that is part of a pharynx [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of pharynx" EXACT [OBOL:automatic] synonym: "epithelium of pharynx" EXACT [OBOL:automatic] synonym: "pharynx epithelial tissue" EXACT [OBOL:automatic] synonym: "pharynx epithelium" EXACT [OBOL:automatic] xref: BSA:0000112 xref: BTO:0005240 xref: EMAPA:16708 xref: MA:0002725 xref: RETIRED_EHDAA2:0001460 xref: TAO:0001174 xref: XAO:0003202 xref: ZFA:0001174 is_a: UBERON:0000490 {gci_relation="BFO:0000050", gci_filler="NCBITaxon:7955", source="ZFA"} ! unilaminar epithelium is_a: UBERON:0003929 ! digestive tract epithelium is_a: UBERON:0004807 ! respiratory system epithelium is_a: UBERON:0005911 ! endo-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: BFO:0000050 UBERON:0001042 ! part of chordate pharynx relationship: BFO:0000050 UBERON:0001042 {source="ZFA"} ! part of chordate pharynx relationship: RO:0002202 UBERON:0007690 {source="ZFA"} ! develops from early pharyngeal endoderm [Term] id: UBERON:0003352 name: epithelium of midgut namespace: uberon def: "An epithelium that is part of a midgut." [OBOL:automatic] synonym: "epithelial tissue of midgut" EXACT [OBOL:automatic] synonym: "midgut epithelial tissue" EXACT [OBOL:automatic] synonym: "midgut epithelium" EXACT [BTO:0005053, OBOL:automatic] xref: BTO:0005053 xref: EHDAA2:0001195 xref: EMAPA:16569 xref: MA:0003205 is_a: UBERON:0003929 ! digestive tract epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: BFO:0000050 UBERON:0001045 ! part of midgut relationship: BFO:0000050 UBERON:0001045 {source="BTO"} ! part of midgut [Term] id: UBERON:0003353 name: epithelium of hindgut namespace: uberon def: "An epithelium that is part of a hindgut [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of hindgut" EXACT [OBOL:automatic] synonym: "hindgut epithelial tissue" EXACT [OBOL:automatic] synonym: "hindgut epithelium" EXACT [OBOL:automatic] xref: EHDAA2:0000782 xref: EMAPA:16717 xref: MA:0003206 is_a: UBERON:0003929 ! digestive tract epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: BFO:0000050 UBERON:0001046 ! part of hindgut relationship: BFO:0000050 UBERON:0001046 ! part of hindgut [Term] id: UBERON:0003354 name: epithelium of rectum namespace: uberon def: "An epithelium that is part of a rectum [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of rectum" EXACT [OBOL:automatic] synonym: "rectal epithelium" EXACT [FMA:17510] synonym: "rectum epithelial tissue" EXACT [OBOL:automatic] synonym: "rectum epithelium" EXACT [OBOL:automatic] xref: CALOHA:TS-2066 xref: EHDAA2:0001594 xref: EMAPA:17898 xref: FMA:17510 xref: MA:0003219 xref: VHOG:0001037 is_a: UBERON:0001278 ! epithelium of large intestine is_a: UBERON:0016885 ! epithelium of terminal part of digestive tract intersection_of: UBERON:0000483 ! epithelium intersection_of: BFO:0000050 UBERON:0001052 ! part of rectum relationship: BFO:0000050 UBERON:0001052 ! part of rectum [Term] id: UBERON:0003364 name: epithelium of right lung namespace: uberon def: "An epithelium that is part of a right lung [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of right lung" EXACT [OBOL:automatic] synonym: "right lung epithelial tissue" EXACT [OBOL:automatic] synonym: "right lung epithelium" EXACT [OBOL:automatic] xref: EMAPA:17663 xref: MA:0003132 is_a: UBERON:0000115 ! lung epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: BFO:0000050 UBERON:0002167 ! part of right lung relationship: BFO:0000050 UBERON:0002167 ! part of right lung [Term] id: UBERON:0003365 name: epithelium of left lung namespace: uberon def: "An epithelium that is part of a left lung [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of left lung" EXACT [OBOL:automatic] synonym: "left lung epithelial tissue" EXACT [OBOL:automatic] synonym: "left lung epithelium" EXACT [OBOL:automatic] xref: EMAPA:17655 xref: MA:0003131 is_a: UBERON:0000115 ! lung epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: BFO:0000050 UBERON:0002168 ! part of left lung relationship: BFO:0000050 UBERON:0002168 ! part of left lung [Term] id: UBERON:0003371 name: pelvic appendage bud ectoderm namespace: uberon def: "An unilaminar epithelium that surrounds a pelvic appendage bud." [OBOL:automatic] synonym: "hindlimb ectoderm" EXACT [VHOG:0001048] xref: EHDAA2:0001034 xref: EMAPA:16780 xref: VHOG:0001048 is_a: UBERON:0000490 ! unilaminar epithelium is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0010371 ! ecto-epithelium intersection_of: UBERON:0000490 ! unilaminar epithelium intersection_of: RO:0002007 UBERON:0005420 ! bounding layer of pelvic appendage bud relationship: BFO:0000050 UBERON:0000076 {source="EHDAA2"} ! part of external ectoderm relationship: RO:0002007 UBERON:0005420 ! bounding layer of pelvic appendage bud relationship: RO:0002202 UBERON:0000076 {source="EHDAA2"} ! develops from external ectoderm [Term] id: UBERON:0003372 name: pectoral appendage bud ectoderm namespace: uberon def: "An unilaminar epithelium that surrounds a pectoral appendage bud." [OBOL:automatic] xref: EHDAA2:0002134 xref: EMAPA:16407 xref: VHOG:0001047 is_a: UBERON:0000490 ! unilaminar epithelium is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0010371 ! ecto-epithelium intersection_of: UBERON:0000490 ! unilaminar epithelium intersection_of: RO:0002007 UBERON:0005419 ! bounding layer of pectoral appendage bud relationship: BFO:0000050 UBERON:0000076 {source="EHDAA2"} ! part of external ectoderm relationship: RO:0002007 UBERON:0005419 ! bounding layer of pectoral appendage bud relationship: RO:0002202 UBERON:0000076 {source="EHDAA2"} ! develops from external ectoderm [Term] id: UBERON:0003374 name: chorionic ectoderm namespace: uberon def: "An extraembryonic structure that develops_from a ectoderm and is part of a chorion." [OBOL:automatic] synonym: "chorion ectoderm" EXACT [OBOL:automatic] xref: BTO:0005145 xref: EMAPA:16113 is_a: UBERON:0000478 ! extraembryonic structure intersection_of: UBERON:0000478 ! extraembryonic structure intersection_of: BFO:0000050 UBERON:0003124 ! part of chorion membrane intersection_of: RO:0002202 UBERON:0000924 ! develops from ectoderm relationship: BFO:0000050 UBERON:0003124 ! part of chorion membrane relationship: RO:0002202 UBERON:0000924 {source="ISBN:0073040584"} ! develops from ectoderm [Term] id: UBERON:0003379 name: cardiac muscle of right atrium namespace: uberon def: "A portion of cardiac muscle tissue that is part of a right atrium [Automatically generated definition]." [OBOL:automatic] synonym: "cardiac muscle of cardiac right atrium" EXACT [OBOL:automatic] synonym: "cardiac muscle of heart right atrium" EXACT [OBOL:automatic] synonym: "cardiac muscle tissue of heart right atrium" EXACT [OBOL:automatic] synonym: "cardiac muscle tissue of right atrium" EXACT [OBOL:automatic] synonym: "cardiac muscle tissue of right atrium of heart" EXACT [OBOL:automatic] synonym: "myocardium of right atrium" EXACT [] synonym: "right atrium heart muscle" EXACT [EHDAA2:0004155] synonym: "right atrium myocardium" EXACT [VHOG:0001227] synonym: "textus muscularis of myocardium of right atrium" EXACT [OBOL:automatic] synonym: "textus muscularis of myocardium of right atrium of heart" EXACT [OBOL:automatic] synonym: "textus muscularis of myocardium of right cardiac atrium" EXACT [OBOL:automatic] xref: EHDAA2:0004155 xref: EMAPA:17326 xref: FMA:7282 xref: SCTID:362018002 xref: VHOG:0001227 is_a: UBERON:0004490 ! cardiac muscle tissue of atrium intersection_of: UBERON:0001133 ! cardiac muscle tissue intersection_of: BFO:0000050 UBERON:0002078 ! part of right cardiac atrium relationship: BFO:0000050 UBERON:0002078 ! part of right cardiac atrium [Term] id: UBERON:0003380 name: cardiac muscle of left atrium namespace: uberon def: "A portion of cardiac muscle tissue that is part of a left atrium [Automatically generated definition]." [OBOL:automatic] synonym: "cardiac left atrium cardiac muscle" EXACT [OBOL:automatic] synonym: "cardiac left atrium cardiac muscle tissue" EXACT [OBOL:automatic] synonym: "cardiac muscle of cardiac left atrium" EXACT [OBOL:automatic] synonym: "cardiac muscle of heart left atrium" EXACT [OBOL:automatic] synonym: "cardiac muscle of left atrium of heart" EXACT [OBOL:automatic] synonym: "left atrium heart muscle" EXACT [EHDAA2:0004154] synonym: "left atrium myocardium" EXACT [VHOG:0001225] synonym: "myocardium of left atrium" EXACT [] synonym: "textus muscularis of myocardium of cardiac left atrium" EXACT [OBOL:automatic] synonym: "textus muscularis of myocardium of heart left atrium" EXACT [OBOL:automatic] synonym: "textus muscularis of myocardium of left atrium" EXACT [OBOL:automatic] synonym: "textus muscularis of myocardium of left atrium of heart" EXACT [OBOL:automatic] synonym: "textus muscularis of myocardium of left cardiac atrium" EXACT [OBOL:automatic] xref: EHDAA2:0004154 xref: EMAPA:17320 xref: FMA:7285 xref: SCTID:189936008 xref: VHOG:0001225 is_a: UBERON:0004490 ! cardiac muscle tissue of atrium intersection_of: UBERON:0001133 ! cardiac muscle tissue intersection_of: BFO:0000050 UBERON:0002079 ! part of left cardiac atrium relationship: BFO:0000050 UBERON:0002079 ! part of left cardiac atrium [Term] id: UBERON:0003381 name: cardiac muscle of right ventricle namespace: uberon def: "A portion of cardiac muscle tissue that is part of a right ventricle [Automatically generated definition]." [OBOL:automatic] synonym: "cardiac muscle tissue of right ventricle" EXACT [FMA:83452] synonym: "right ventricular cardiac muscle tissue" EXACT [GO:0003221] xref: EMAPA:17342 xref: FMA:83452 xref: VHOG:0001236 is_a: UBERON:0018649 ! cardiac muscle tissue of ventricle intersection_of: UBERON:0001133 ! cardiac muscle tissue intersection_of: BFO:0000050 UBERON:0002080 ! part of heart right ventricle relationship: BFO:0000050 UBERON:0002080 ! part of heart right ventricle [Term] id: UBERON:0003382 name: cardiac muscle of left ventricle namespace: uberon def: "A portion of cardiac muscle tissue that is part of a left ventricle [Automatically generated definition]." [OBOL:automatic] synonym: "cardiac muscle tissue of left ventricle" EXACT [FMA:83453] synonym: "left ventricular cardiac muscle tissue" EXACT [GO:0003220] xref: EMAPA:17339 xref: FMA:83453 xref: VHOG:0001234 is_a: UBERON:0018649 ! cardiac muscle tissue of ventricle intersection_of: UBERON:0001133 ! cardiac muscle tissue intersection_of: BFO:0000050 UBERON:0002084 ! part of heart left ventricle relationship: BFO:0000050 UBERON:0002084 ! part of heart left ventricle [Term] id: UBERON:0003383 name: cardiac muscle tissue of interventricular septum namespace: uberon def: "A portion of cardiac muscle tissue that is part of an interventricular septum [Automatically generated definition]." [OBOL:automatic] synonym: "cardiac muscle of interventricular septum" EXACT [] synonym: "cardiac muscle tissue of interventricular septum" EXACT [FMA:84084] synonym: "interventricular septum cardiac muscle" EXACT [VHOG:0000999] synonym: "interventricular septum heart muscle" EXACT [EHDAA2:0004158] synonym: "interventricular septum myocardium" EXACT [VHOG:0000999] xref: EHDAA2:0004158 xref: EMAPA:17335 xref: FMA:84084 xref: VHOG:0000999 is_a: UBERON:0004492 ! cardiac muscle tissue of cardiac septum is_a: UBERON:0004667 ! interventricular septum muscular part intersection_of: UBERON:0001133 ! cardiac muscle tissue intersection_of: BFO:0000050 UBERON:0002094 ! part of interventricular septum [Term] id: UBERON:0003384 name: skeletal muscle tissue of pharynx namespace: uberon def: "A portion of skeletal muscle tissue that is part of a pharynx [Automatically generated definition]." [OBOL:automatic] synonym: "pharynx skeletal muscle" EXACT [OBOL:automatic] synonym: "pharynx skeletal muscle tissue" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue of pharynx" EXACT [OBOL:automatic] xref: EMAPA:18963 is_a: UBERON:0004830 ! respiratory system skeletal muscle intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: BFO:0000050 UBERON:0001042 ! part of chordate pharynx relationship: BFO:0000050 UBERON:0001042 ! part of chordate pharynx [Term] id: UBERON:0003386 name: smooth muscle of eye namespace: uberon def: "Any of the striated muscles that move the eye and include: superior rectus, inferior rectus, medial rectus, lateral rectus, superior oblique, inferior oblique, retractor bulbi." [MGI:cwg, MP:0005247] synonym: "ocular smooth muscle" EXACT [MA:0001268] xref: EMAPA:18807 xref: MA:0001268 is_a: UBERON:0001135 ! smooth muscle tissue is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: BFO:0000050 UBERON:0000019 ! part of camera-type eye relationship: BFO:0000050 UBERON:0000019 ! part of camera-type eye relationship: RO:0002433 UBERON:0001015 ! contributes to morphology of musculature [Term] id: UBERON:0003388 name: mesothelium of pericardial cavity namespace: uberon def: "A mesothelium that is part of a pericardium [Automatically generated definition]." [OBOL:automatic] synonym: "cavity of pericardial sac meso-epithelium" EXACT [OBOL:automatic] synonym: "cavity of pericardial sac mesothelium" EXACT [OBOL:automatic] synonym: "meso-epithelium of cavity of pericardial sac" EXACT [OBOL:automatic] synonym: "meso-epithelium of pericardial cavity" EXACT [OBOL:automatic] synonym: "mesothelium of cavity of pericardial sac" EXACT [OBOL:automatic] synonym: "pericardial cavity meso-epithelium" EXACT [OBOL:automatic] synonym: "pericardial cavity mesothelium" EXACT [OBOL:automatic] xref: RETIRED_EHDAA2:0001436 is_a: UBERON:0001136 ! mesothelium intersection_of: UBERON:0001136 ! mesothelium intersection_of: BFO:0000050 UBERON:0002407 ! part of pericardium relationship: BFO:0000050 UBERON:0002407 ! part of pericardium [Term] id: UBERON:0003389 name: mesothelium of diaphragm namespace: uberon def: "A mesothelium that is part of a diaphragm [Automatically generated definition]." [OBOL:automatic] synonym: "diaphragm meso-epithelium" EXACT [OBOL:automatic] synonym: "diaphragm mesothelium" EXACT [OBOL:automatic] synonym: "meso-epithelium of diaphragm" EXACT [OBOL:automatic] synonym: "meso-epithelium of thoracic diaphragm" EXACT [OBOL:automatic] synonym: "mesothelium of thoracic diaphragm" EXACT [OBOL:automatic] synonym: "thoracic diaphragm meso-epithelium" EXACT [OBOL:automatic] synonym: "thoracic diaphragm mesothelium" EXACT [OBOL:automatic] xref: EMAPA:18429 is_a: UBERON:0001136 ! mesothelium is_a: UBERON:0004807 ! respiratory system epithelium intersection_of: UBERON:0001136 ! mesothelium intersection_of: BFO:0000050 UBERON:0001103 ! part of diaphragm relationship: BFO:0000050 UBERON:0001103 ! part of diaphragm [Term] id: UBERON:0003390 name: mesothelium of pleural cavity namespace: uberon def: "A mesothelium that is part of a pleural cavity [Automatically generated definition]." [OBOL:automatic] synonym: "meso-epithelium of pleural cavity" EXACT [OBOL:automatic] synonym: "mesothelium of pleura" EXACT [FMA:18148] synonym: "pleural cavity meso-epithelium" EXACT [OBOL:automatic] synonym: "pleural cavity mesothelium" EXACT [OBOL:automatic] synonym: "pleural mesothelium" EXACT [EMAPA:16775] xref: BTO:0003155 xref: EHDAA2:0001476 xref: EMAPA:16775 xref: FMA:18148 is_a: UBERON:0001136 ! mesothelium intersection_of: UBERON:0001136 ! mesothelium intersection_of: RO:0001025 UBERON:0002402 ! located in pleural cavity relationship: RO:0001025 UBERON:0002402 ! located in pleural cavity [Term] id: UBERON:0003393 name: mesentery of urinary system namespace: uberon def: "A mesentery that is part of a urinary system [Automatically generated definition]." [OBOL:automatic] synonym: "excretory system mesentery" EXACT [OBOL:automatic] synonym: "mesentery of excretory system" EXACT [OBOL:automatic] synonym: "mesentery of renal system" EXACT [OBOL:automatic] synonym: "mesentery of systema urinaria" EXACT [OBOL:automatic] synonym: "renal system mesentery" EXACT [OBOL:automatic] synonym: "systema urinaria mesentery" EXACT [OBOL:automatic] synonym: "urinary system mesentery" EXACT [OBOL:automatic] xref: EMAPA:17367 xref: MA:0003233 is_a: UBERON:0002095 ! mesentery intersection_of: UBERON:0002095 ! mesentery intersection_of: BFO:0000050 UBERON:0001008 ! part of renal system relationship: BFO:0000050 UBERON:0001008 ! part of renal system [Term] id: UBERON:0003394 name: mesentery of hindgut namespace: uberon def: "A mesentery that is part of a hindgut [Automatically generated definition]." [OBOL:automatic] synonym: "hindgut mesentery" EXACT [OBOL:automatic] xref: EMAPA:16718 is_a: UBERON:0002095 ! mesentery intersection_of: UBERON:0002095 ! mesentery intersection_of: BFO:0000050 UBERON:0001046 ! part of hindgut relationship: BFO:0000050 UBERON:0001046 ! part of hindgut [Term] id: UBERON:0003395 name: mesentery of rectum namespace: uberon def: "A mesentery that is part of a rectum [Automatically generated definition]." [OBOL:automatic] synonym: "rectum mesentery" EXACT [OBOL:automatic] xref: EMAPA:18664 is_a: UBERON:0003334 ! serosa of rectum is_a: UBERON:0004854 ! gastrointestinal system mesentery intersection_of: UBERON:0002095 ! mesentery intersection_of: BFO:0000050 UBERON:0001052 ! part of rectum [Term] id: UBERON:0003396 name: mesentery of colon namespace: uberon def: "A mesentery that is part of a colon [Automatically generated definition]." [OBOL:automatic] synonym: "colon mesentery" EXACT [OBOL:automatic] synonym: "large bowel mesentery" EXACT [OBOL:automatic] synonym: "large intestinal mesentery" EXACT [FMA:14645] synonym: "mesentery of large bowel" EXACT [OBOL:automatic] synonym: "mesentery of large intestine" EXACT [FMA:14645] synonym: "mesocolon" EXACT [https://github.com/obophenotype/uberon/issues/1473] xref: EMAPA:18942 xref: FMA:14645 xref: SCTID:245457004 is_a: UBERON:0003335 ! serosa of colon is_a: UBERON:0004854 ! gastrointestinal system mesentery is_a: UBERON:0007826 {source="FMA"} ! peritoneal mesentery intersection_of: UBERON:0002095 ! mesentery intersection_of: BFO:0000050 UBERON:0001155 ! part of colon [Term] id: UBERON:0003397 name: mesentery of duodenum namespace: uberon def: "A mesentery that is part of a duodenum [Automatically generated definition]." [OBOL:automatic] synonym: "duodenum mesentery" EXACT [OBOL:automatic] xref: EMAPA:19081 is_a: UBERON:0001170 ! mesentery of small intestine is_a: UBERON:0003336 ! serosa of duodenum intersection_of: UBERON:0002095 ! mesentery intersection_of: BFO:0000050 UBERON:0002114 ! part of duodenum [Term] id: UBERON:0003406 name: cartilage of respiratory system namespace: uberon def: "A cartilage element that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "apparatus respiratorius cartilage" EXACT [OBOL:automatic] synonym: "cartilage of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "respiratory system cartilage" EXACT [OBOL:automatic] xref: EMAPA:18694 xref: MA:0001818 is_a: UBERON:0007844 ! cartilage element intersection_of: UBERON:0007844 ! cartilage element intersection_of: BFO:0000050 UBERON:0001004 ! part of respiratory system relationship: BFO:0000050 UBERON:0001004 ! part of respiratory system [Term] id: UBERON:0003408 name: gland of digestive tract namespace: uberon def: "A gland that is part of a digestive tract [Automatically generated definition]." [OBOL:automatic] synonym: "digestive tract gland" EXACT [OBOL:automatic] synonym: "gland of digestive tract" EXACT [OBOL:automatic] synonym: "gland of lower gastrointestinal tract" EXACT [OBOL:automatic] synonym: "gut gland" EXACT [MA:0003202] synonym: "lower gastrointestinal tract gland" EXACT [OBOL:automatic] xref: EMAPA:18815 xref: MA:0003202 is_a: UBERON:0002530 ! gland is_a: UBERON:0013765 ! digestive system element intersection_of: UBERON:0002530 ! gland intersection_of: BFO:0000050 UBERON:0001555 ! part of digestive tract relationship: BFO:0000050 UBERON:0001555 ! part of digestive tract [Term] id: UBERON:0003412 name: pelvic appendage bud mesenchyme namespace: uberon def: "Mesenchyme that is part of a pelvic appendage bud." [OBOL:automatic] synonym: "leg mesenchyme" EXACT [OBOL:automatic] synonym: "lower limb bud mesenchyme" EXACT [EHDAA2:0001035] xref: EHDAA2:0001035 xref: EMAPA:16781 xref: TAO:0001386 xref: ZFA:0001386 is_a: UBERON:0010329 ! paired limb/fin bud mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: BFO:0000050 UBERON:0005420 ! part of pelvic appendage bud relationship: BFO:0000050 UBERON:0005420 ! part of pelvic appendage bud relationship: RO:0002202 UBERON:0005730 ! develops from pelvic appendage field [Term] id: UBERON:0003413 name: pectoral appendage bud mesenchyme namespace: uberon def: "Mesenchyme that is part of a pectoral appendage bud." [OBOL:automatic] xref: EHDAA2:0002135 xref: EHDAA:1703 xref: EMAPA:16408 xref: TAO:0000789 xref: ZFA:0000789 is_a: UBERON:0010329 ! paired limb/fin bud mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: BFO:0000050 UBERON:0005419 ! part of pectoral appendage bud relationship: BFO:0000050 UBERON:0005419 ! part of pectoral appendage bud relationship: RO:0002202 UBERON:0005729 ! develops from pectoral appendage field [Term] id: UBERON:0003422 name: mesenchyme of umbilical cord namespace: uberon def: "A gelatinous substance within the umbilical cord, largely made up of mucopolysaccharides (hyaluronic acid and chondroitin sulfate). It also contains some fibroblasts and macrophages. It is derived from Extra Embryonic Mesoderm[WP]." [Wikipedia:Wharton's_jelly] synonym: "umbilical cord mesenchyme" EXACT [OBOL:automatic] synonym: "Wharton's jelly" EXACT [EMAPA:26127] xref: EMAPA:26127 xref: EMAPA:35925 xref: SCTID:368069009 xref: Wikipedia:Wharton's_jelly is_a: UBERON:0003104 ! mesenchyme is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005292 ! extraembryonic tissue intersection_of: UBERON:0003104 ! mesenchyme intersection_of: BFO:0000050 UBERON:0002331 ! part of umbilical cord relationship: BFO:0000050 UBERON:0002331 ! part of umbilical cord relationship: BFO:0000051 CHEBI:37395 {source="Wikipedia"} ! has part mucopolysaccharide [Term] id: UBERON:0003426 name: dermis adipose tissue namespace: uberon def: "An adipose tissue that is part of a dermis [Automatically generated definition]." [OBOL:automatic] synonym: "adipose tissue of dermis" EXACT [OBOL:automatic] synonym: "dermis fat tissue" EXACT [OBOL:automatic] synonym: "dermis fatty tissue" EXACT [OBOL:automatic] synonym: "fat tissue of dermis" EXACT [OBOL:automatic] synonym: "fatty tissue of dermis" EXACT [OBOL:automatic] xref: MA:0000798 is_a: UBERON:0001013 ! adipose tissue is_a: UBERON:0003585 ! dermis connective tissue intersection_of: UBERON:0001013 ! adipose tissue intersection_of: BFO:0000050 UBERON:0002067 ! part of dermis [Term] id: UBERON:0003429 name: abdomen nerve namespace: uberon def: "A nerve that is part of an abdomen [Automatically generated definition]." [OBOL:automatic] synonym: "nerve of abdomen" EXACT [OBOL:automatic] xref: MA:0000521 is_a: UBERON:0003825 ! nerve of abdominal segment intersection_of: UBERON:0001021 ! nerve intersection_of: BFO:0000050 UBERON:0000916 ! part of abdomen relationship: BFO:0000050 UBERON:0000916 ! part of abdomen [Term] id: UBERON:0003430 name: neck nerve namespace: uberon def: "A nerve that is part of a neck [Automatically generated definition]." [OBOL:automatic] synonym: "neck (volume) nerve" EXACT [OBOL:automatic] synonym: "nerve of neck" EXACT [OBOL:automatic] synonym: "nerve of neck (volume)" EXACT [OBOL:automatic] xref: EMAPA:37263 {source="MA:th"} xref: MA:0000588 is_a: UBERON:0001021 ! nerve intersection_of: UBERON:0001021 ! nerve intersection_of: BFO:0000050 UBERON:0000974 ! part of neck relationship: BFO:0000050 UBERON:0000974 ! part of neck [Term] id: UBERON:0003438 name: iris nerve namespace: uberon def: "Any nerve that innervates the iris." [UBERON:cjm] synonym: "nerve of iris" EXACT [OBOL:automatic] xref: EMAPA:35449 xref: MA:0001291 is_a: UBERON:0001021 ! nerve intersection_of: UBERON:0001021 ! nerve intersection_of: RO:0002134 UBERON:0001769 ! innervates iris relationship: RO:0002134 UBERON:0001769 ! innervates iris [Term] id: UBERON:0003439 name: nerve of trunk region namespace: uberon def: "A nerve that is part of the trunk region of the body (not to be confused with a nerve trunk)." [http://orcid.org/0000-0002-6601-2165] synonym: "nerve of torso" EXACT [OBOL:automatic] synonym: "nerve of trunk" EXACT [OBOL:automatic] synonym: "torso nerve" EXACT [OBOL:automatic] xref: EMAPA:37264 {source="MA:th"} xref: MA:0000515 is_a: UBERON:0001021 ! nerve intersection_of: UBERON:0001021 ! nerve intersection_of: BFO:0000050 UBERON:0002100 ! part of trunk relationship: BFO:0000050 UBERON:0002100 ! part of trunk [Term] id: UBERON:0003443 name: thoracic cavity nerve namespace: uberon def: "A nerve that is located in a thoracic cavity [Automatically generated definition]." [OBOL:automatic] synonym: "cavity of chest nerve" EXACT [OBOL:automatic] synonym: "cavity of thorax nerve" EXACT [OBOL:automatic] synonym: "chest cavity nerve" EXACT [OBOL:automatic] synonym: "nerve of cavity of chest" EXACT [OBOL:automatic] synonym: "nerve of cavity of thorax" EXACT [OBOL:automatic] synonym: "nerve of chest cavity" EXACT [OBOL:automatic] synonym: "nerve of pectoral cavity" EXACT [OBOL:automatic] synonym: "nerve of thoracic cavity" EXACT [OBOL:automatic] synonym: "pectoral cavity nerve" EXACT [OBOL:automatic] xref: EMAPA:37267 {source="MA:th"} xref: MA:0000556 is_a: UBERON:0001021 ! nerve intersection_of: UBERON:0001021 ! nerve intersection_of: RO:0001025 UBERON:0002224 ! located in thoracic cavity relationship: RO:0001025 UBERON:0002224 ! located in thoracic cavity [Term] id: UBERON:0003444 name: pelvis nerve namespace: uberon def: "A nerve that is part of a pelvis [Automatically generated definition]." [OBOL:automatic] synonym: "nerve of pelvis" EXACT [OBOL:automatic] xref: EMAPA:37269 {source="MA:th"} xref: MA:0000542 is_a: UBERON:0003825 ! nerve of abdominal segment intersection_of: UBERON:0001021 ! nerve intersection_of: BFO:0000050 UBERON:0002355 ! part of pelvic region of trunk relationship: BFO:0000050 UBERON:0002355 ! part of pelvic region of trunk [Term] id: UBERON:0003452 name: trabecula carnea cardiac muscle tissue namespace: uberon def: "A portion of cardiac muscle tissue that is part of a trabecula carnea [Automatically generated definition]." [OBOL:automatic] synonym: "cardiac muscle muscle tissue of trabecula carnea" EXACT [OBOL:automatic] synonym: "cardiac muscle of trabecula carnea" EXACT [OBOL:automatic] synonym: "cardiac muscle textus muscularis of trabecula carnea" EXACT [OBOL:automatic] synonym: "cardiac muscle tissue of trabecula carnea" EXACT [OBOL:automatic] synonym: "heart muscle muscle tissue of trabecula carnea" EXACT [OBOL:automatic] synonym: "heart muscle textus muscularis of trabecula carnea" EXACT [OBOL:automatic] synonym: "heart myocardium muscle tissue of trabecula carnea" EXACT [OBOL:automatic] synonym: "heart myocardium textus muscularis of trabecula carnea" EXACT [OBOL:automatic] synonym: "muscle of heart muscle tissue of trabecula carnea" EXACT [OBOL:automatic] synonym: "muscle of heart textus muscularis of trabecula carnea" EXACT [OBOL:automatic] synonym: "muscle tissue of cardiac muscle of trabecula carnea" EXACT [OBOL:automatic] synonym: "muscle tissue of heart muscle of trabecula carnea" EXACT [OBOL:automatic] synonym: "muscle tissue of heart myocardium of trabecula carnea" EXACT [OBOL:automatic] synonym: "muscle tissue of muscle of heart of trabecula carnea" EXACT [OBOL:automatic] synonym: "muscle tissue of myocardium of trabecula carnea" EXACT [OBOL:automatic] synonym: "myocardium muscle tissue of trabecula carnea" EXACT [OBOL:automatic] synonym: "myocardium textus muscularis of trabecula carnea" EXACT [OBOL:automatic] synonym: "textus muscularis of cardiac muscle of trabecula carnea" EXACT [OBOL:automatic] synonym: "textus muscularis of heart muscle of trabecula carnea" EXACT [OBOL:automatic] synonym: "textus muscularis of heart myocardium of trabecula carnea" EXACT [OBOL:automatic] synonym: "textus muscularis of muscle of heart of trabecula carnea" EXACT [OBOL:automatic] synonym: "textus muscularis of myocardium of trabecula carnea" EXACT [OBOL:automatic] synonym: "trabecula carnea cardiac muscle" EXACT [OBOL:automatic] synonym: "trabecula carnea cardiac muscle muscle tissue" EXACT [OBOL:automatic] synonym: "trabecula carnea cardiac muscle textus muscularis" EXACT [OBOL:automatic] synonym: "trabecula carnea heart muscle muscle tissue" EXACT [OBOL:automatic] synonym: "trabecula carnea heart muscle textus muscularis" EXACT [OBOL:automatic] synonym: "trabecula carnea heart myocardium muscle tissue" EXACT [OBOL:automatic] synonym: "trabecula carnea heart myocardium textus muscularis" EXACT [OBOL:automatic] synonym: "trabecula carnea muscle of heart muscle tissue" EXACT [OBOL:automatic] synonym: "trabecula carnea muscle of heart textus muscularis" EXACT [OBOL:automatic] synonym: "trabecula carnea muscle tissue of cardiac muscle" EXACT [OBOL:automatic] synonym: "trabecula carnea muscle tissue of heart muscle" EXACT [OBOL:automatic] synonym: "trabecula carnea muscle tissue of heart myocardium" EXACT [OBOL:automatic] synonym: "trabecula carnea muscle tissue of muscle of heart" EXACT [OBOL:automatic] synonym: "trabecula carnea muscle tissue of myocardium" EXACT [OBOL:automatic] synonym: "trabecula carnea myocardium muscle tissue" EXACT [OBOL:automatic] synonym: "trabecula carnea myocardium textus muscularis" EXACT [OBOL:automatic] synonym: "trabecula carnea textus muscularis of cardiac muscle" EXACT [OBOL:automatic] synonym: "trabecula carnea textus muscularis of heart muscle" EXACT [OBOL:automatic] synonym: "trabecula carnea textus muscularis of heart myocardium" EXACT [OBOL:automatic] synonym: "trabecula carnea textus muscularis of muscle of heart" EXACT [OBOL:automatic] synonym: "trabecula carnea textus muscularis of myocardium" EXACT [OBOL:automatic] xref: EMAPA:36573 xref: FMA:84428 xref: MA:0002833 is_a: UBERON:0018649 ! cardiac muscle tissue of ventricle intersection_of: UBERON:0001133 ! cardiac muscle tissue intersection_of: BFO:0000050 UBERON:0002511 ! part of trabecula carnea relationship: BFO:0000050 UBERON:0002511 ! part of trabecula carnea [Term] id: UBERON:0003457 name: head bone namespace: uberon def: "A bone that is part of a head [Automatically generated definition]." [OBOL:automatic] synonym: "adult head bone" EXACT [OBOL:automatic] synonym: "adult head bone organ" EXACT [OBOL:automatic] synonym: "bone of adult head" EXACT [OBOL:automatic] synonym: "bone of head" EXACT [OBOL:automatic] synonym: "bone organ of adult head" EXACT [OBOL:automatic] synonym: "bone organ of head" EXACT [OBOL:automatic] synonym: "head bone organ" EXACT [OBOL:automatic] xref: EMAPA:35996 xref: MA:0000576 xref: SCTID:118646007 is_a: UBERON:0007914 ! bone of craniocervical region intersection_of: UBERON:0001474 ! bone element intersection_of: BFO:0000050 UBERON:0000033 ! part of head relationship: BFO:0000050 UBERON:0000033 ! part of head [Term] id: UBERON:0003458 name: neck bone namespace: uberon def: "A bone that is part of a neck [Automatically generated definition]." [OBOL:automatic] synonym: "bone of neck" EXACT [OBOL:automatic] synonym: "bone of neck (volume)" EXACT [OBOL:automatic] synonym: "bone organ of neck" EXACT [OBOL:automatic] synonym: "bone organ of neck (volume)" EXACT [OBOL:automatic] synonym: "neck (volume) bone" EXACT [OBOL:automatic] synonym: "neck (volume) bone organ" EXACT [OBOL:automatic] synonym: "neck bone organ" EXACT [OBOL:automatic] xref: EMAPA:37246 {source="MA:th"} xref: MA:0000584 is_a: UBERON:0001474 ! bone element intersection_of: UBERON:0001474 ! bone element intersection_of: BFO:0000050 UBERON:0000974 ! part of neck relationship: BFO:0000050 UBERON:0000974 ! part of neck [Term] id: UBERON:0003462 name: facial bone namespace: uberon def: "A bone that is part of a facial skeleton [Automatically generated definition]." [OBOL:automatic] synonym: "bone of facial skeleton" EXACT [OBOL:automatic] synonym: "facial bone" EXACT [EMAPA:19019] synonym: "facial skeleton bone" EXACT [OBOL:automatic] xref: EMAPA:19019 xref: EMAPA:35924 xref: MA:0001482 xref: MA:0003159 xref: NCIT:C63706 xref: SCTID:181799005 xref: UMLS:C0015455 {source="ncithesaurus:Facial_Bone"} is_a: UBERON:0003457 ! head bone is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: UBERON:0001474 ! bone element intersection_of: BFO:0000050 UBERON:0011156 ! part of facial skeleton relationship: BFO:0000050 UBERON:0011156 {source="MA"} ! part of facial skeleton [Term] id: UBERON:0003463 name: trunk bone namespace: uberon def: "A bone that is part of a trunk [Automatically generated definition]." [OBOL:automatic] synonym: "bone of torso" EXACT [OBOL:automatic] synonym: "bone of trunk" EXACT [OBOL:automatic] synonym: "bone organ of torso" EXACT [OBOL:automatic] synonym: "bone organ of trunk" EXACT [OBOL:automatic] synonym: "torso bone" EXACT [OBOL:automatic] synonym: "torso bone organ" EXACT [OBOL:automatic] synonym: "trunk bone organ" EXACT [OBOL:automatic] xref: EMAPA:36583 xref: MA:0000512 xref: SCTID:427358002 is_a: UBERON:0001474 ! bone element is_a: UBERON:0005177 ! trunk region element intersection_of: UBERON:0001474 ! bone element intersection_of: BFO:0000050 UBERON:0002100 ! part of trunk [Term] id: UBERON:0003468 name: ureteric segment of renal artery namespace: uberon def: "The ureteral branches of renal artery are small branches which supply the ureter." [Wikipedia:Ureteral_branches_of_renal_artery] xref: EMAPA:37676 {source="MA:th"} xref: FMA:70491 xref: MA:0002074 xref: SCTID:65376008 xref: Wikipedia:Ureteral_branches_of_renal_artery is_a: UBERON:0004573 ! systemic artery intersection_of: UBERON:0001637 ! artery intersection_of: RO:0002178 UBERON:0000056 ! supplies ureter relationship: BFO:0000050 UBERON:0001184 {source="FMA"} ! part of renal artery relationship: RO:0002178 UBERON:0000056 ! supplies ureter relationship: RO:0002252 UBERON:0001184 {source="FMA"} ! connecting branch of renal artery [Term] id: UBERON:0003469 name: respiratory system artery namespace: uberon def: "An artery that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:37569 {source="MA:th"} xref: MA:0001804 is_a: UBERON:0001637 ! artery is_a: UBERON:0003643 ! respiratory system arterial blood vessel intersection_of: UBERON:0001637 ! artery intersection_of: BFO:0000050 UBERON:0001004 ! part of respiratory system [Term] id: UBERON:0003470 name: artery of upper lip namespace: uberon def: "The superior labial artery (superior labial branch of facial artery) is larger and more tortuous than the inferior labial artery. It follows a similar course along the edge of the upper lip, lying between the mucous membrane and the Orbicularis oris, and anastomoses with the artery of the opposite side. It supplies the upper lip, and gives off in its course two or three vessels which ascend to the nose; a septal branch ramifies on the nasal septum as far as the point of the nose, and an alar branch supplies the ala of the nose." [Wikipedia:Superior_labial_artery] synonym: "superior labial artery" EXACT [FMA:49570] synonym: "superior labial branch of facial artery" EXACT [FMA:49570] xref: EMAPA:37430 {source="MA:th"} xref: FMA:49570 xref: MA:0001917 xref: SCTID:145137009 xref: Wikipedia:Superior_labial_artery is_a: UBERON:0003496 ! head blood vessel is_a: UBERON:0009657 ! artery of lip intersection_of: UBERON:0001637 ! artery intersection_of: RO:0002178 UBERON:0001834 ! supplies upper lip relationship: RO:0002178 UBERON:0001834 ! supplies upper lip relationship: RO:0002252 UBERON:0001612 {source="FMA"} ! connecting branch of facial artery [Term] id: UBERON:0003471 name: artery of lower lip namespace: uberon def: "The inferior labial artery (inferior labial branch of facial artery) arises near the angle of the mouth; it passes upward and forward beneath the Triangularis and, penetrating the Orbicularis oris, runs in a tortuous course along the edge of the lower lip between this muscle and the mucous membrane. It supplies the labial glands, the mucous membrane, and the muscles of the lower lip; and anastomoses with the artery of the opposite side, and with the mental branch of the inferior alveolar artery." [Wikipedia:Inferior_labial_artery] synonym: "inferior labial artery" EXACT [FMA:49567] synonym: "inferior labial branch of facial artery" EXACT [FMA:49567] synonym: "ramus labialis inferior (arteria facialis)" EXACT [FMA:TA] xref: EMAPA:37429 {source="MA:th"} xref: FMA:49567 xref: MA:0001916 xref: SCTID:145036002 xref: Wikipedia:Inferior_labial_artery is_a: UBERON:0003496 ! head blood vessel is_a: UBERON:0009657 ! artery of lip intersection_of: UBERON:0001637 ! artery intersection_of: RO:0002178 UBERON:0001835 ! supplies lower lip relationship: RO:0002178 UBERON:0001835 ! supplies lower lip relationship: RO:0002252 UBERON:0001612 {source="FMA"} ! connecting branch of facial artery [Term] id: UBERON:0003473 name: thoracic cavity artery namespace: uberon def: "An artery that is part of a thoracic cavity[cjm]." [https://sourceforge.net/tracker/index.php?func=detail&aid=3317815&group_id=76834&atid=1205376] xref: EMAPA:37241 {source="MA:th"} xref: MA:0001902 xref: MESH:D013895 is_a: UBERON:0001637 ! artery is_a: UBERON:0003519 ! thoracic cavity blood vessel intersection_of: UBERON:0001637 ! artery intersection_of: RO:0001025 UBERON:0002224 ! located in thoracic cavity [Term] id: UBERON:0003475 name: ureteric vein namespace: uberon def: "A vein that is part of a ureter [Automatically generated definition]." [OBOL:automatic] synonym: "ureter vein" EXACT [OBOL:automatic] synonym: "vein of ureter" EXACT [OBOL:automatic] xref: EMAPA:37679 {source="MA:th"} xref: MA:0002250 is_a: UBERON:0001638 ! vein is_a: UBERON:0003520 ! pelvis blood vessel intersection_of: UBERON:0001638 ! vein intersection_of: BFO:0000050 UBERON:0000056 ! part of ureter relationship: BFO:0000050 UBERON:0000056 ! part of ureter [Term] id: UBERON:0003476 name: respiratory system venous blood vessel namespace: uberon def: "A vein that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "apparatus respiratorius vein" EXACT [OBOL:automatic] synonym: "respiratory system vein" EXACT [OBOL:automatic] synonym: "vein of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "vein of respiratory system" EXACT [OBOL:automatic] xref: EMAPA:37584 {source="MA:th"} xref: MA:0001809 xref: MA:0001810 is_a: UBERON:0001638 ! vein intersection_of: UBERON:0001638 ! vein intersection_of: RO:0002179 UBERON:0001004 ! drains respiratory system relationship: BFO:0000050 RO:0002577 ! part of system relationship: RO:0002179 UBERON:0001004 ! drains respiratory system [Term] id: UBERON:0003477 name: vein of upper lip namespace: uberon def: "The inferior labial vein is the vein receiving blood from the upper lip." [Wikipedia:Superior_labial_vein] synonym: "superior labial vein" EXACT [FMA:52538] synonym: "upper lip vein" EXACT [OBOL:automatic] xref: EMAPA:37204 {source="MA:th"} xref: FMA:52538 xref: MA:0002255 xref: SCTID:422755007 xref: Wikipedia:Superior_labial_vein is_a: UBERON:0013136 ! vein of lip intersection_of: UBERON:0001638 ! vein intersection_of: RO:0002179 UBERON:0001834 ! drains upper lip relationship: RO:0002179 UBERON:0001834 ! drains upper lip [Term] id: UBERON:0003478 name: vein of lower lip namespace: uberon def: "The inferior labial vein is the vein receiving blood from the lower lip." [Wikipedia:Inferior_labial_vein] synonym: "inferior labial vein" EXACT [FMA:52541] synonym: "lower lip vein" EXACT [OBOL:automatic] xref: EMAPA:37202 {source="MA:th"} xref: FMA:52541 xref: MA:0002253 xref: SCTID:422955002 xref: Wikipedia:Inferior_labial_vein is_a: UBERON:0013136 ! vein of lip intersection_of: UBERON:0001638 ! vein intersection_of: RO:0002179 UBERON:0001835 ! drains lower lip relationship: RO:0002179 UBERON:0001835 ! drains lower lip property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/8/8c/Gray557.png" xsd:anyURI [Term] id: UBERON:0003479 name: thoracic cavity vein namespace: uberon def: "A vein that is part of a thoracic cavity [Automatically generated definition]." [OBOL:automatic] synonym: "cavity of chest vein" EXACT [OBOL:automatic] synonym: "cavity of thorax vein" EXACT [OBOL:automatic] synonym: "chest cavity vein" EXACT [OBOL:automatic] synonym: "pectoral cavity vein" EXACT [OBOL:automatic] synonym: "vein of cavity of chest" EXACT [OBOL:automatic] synonym: "vein of cavity of thorax" EXACT [OBOL:automatic] synonym: "vein of chest cavity" EXACT [OBOL:automatic] synonym: "vein of pectoral cavity" EXACT [OBOL:automatic] synonym: "vein of thoracic cavity" EXACT [OBOL:automatic] xref: EMAPA:37242 {source="MA:th"} xref: MA:0001903 is_a: UBERON:0001638 ! vein is_a: UBERON:0003519 ! thoracic cavity blood vessel intersection_of: UBERON:0001638 ! vein intersection_of: RO:0001025 UBERON:0002224 ! located in thoracic cavity [Term] id: UBERON:0003480 name: vein of clitoris namespace: uberon def: "A vein that is part of a clitoris [Automatically generated definition]." [OBOL:automatic] synonym: "clitoris vein" EXACT [OBOL:automatic] xref: EMAPA:37201 {source="MA:th"} xref: MA:0002252 xref: SCTID:360819004 is_a: UBERON:0001638 ! vein is_a: UBERON:0005156 ! reproductive structure intersection_of: UBERON:0001638 ! vein intersection_of: BFO:0000050 UBERON:0002411 ! part of clitoris relationship: BFO:0000050 UBERON:0002411 ! part of clitoris [Term] id: UBERON:0003481 name: tail vein namespace: uberon def: "A vein that is part of a tail [Automatically generated definition]." [OBOL:automatic, Wikipedia:Tail_vein] synonym: "post-vent region vein" EXACT [OBOL:automatic] synonym: "vein of post-vent region" EXACT [OBOL:automatic] synonym: "vein of tail" EXACT [OBOL:automatic] xref: AAO:0011105 xref: EMAPA:37761 {source="MA:th"} xref: MA:0002233 xref: Wikipedia:Tail_vein xref: XAO:0000393 is_a: UBERON:0001638 ! vein is_a: UBERON:0003524 ! tail blood vessel intersection_of: UBERON:0001638 ! vein intersection_of: BFO:0000050 UBERON:0007812 ! part of post-anal tail [Term] id: UBERON:0003489 name: respiratory system capillary endothelium namespace: uberon def: "An endothelium of capillary that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "apparatus respiratorius blood capillary endothelium" EXACT [OBOL:automatic] synonym: "apparatus respiratorius capillary endothelium" EXACT [OBOL:automatic] synonym: "apparatus respiratorius capillary vessel endothelium" EXACT [OBOL:automatic] synonym: "apparatus respiratorius endothelium of blood capillary" EXACT [OBOL:automatic] synonym: "apparatus respiratorius endothelium of capillary" EXACT [OBOL:automatic] synonym: "apparatus respiratorius endothelium of capillary vessel" EXACT [OBOL:automatic] synonym: "blood capillary endothelium of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "blood capillary endothelium of respiratory system" EXACT [OBOL:automatic] synonym: "capillary endothelium of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "capillary endothelium of respiratory system" EXACT [OBOL:automatic] synonym: "capillary vessel endothelium of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "capillary vessel endothelium of respiratory system" EXACT [OBOL:automatic] synonym: "endothelium of blood capillary of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "endothelium of blood capillary of respiratory system" EXACT [OBOL:automatic] synonym: "endothelium of capillary of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "endothelium of capillary of respiratory system" EXACT [OBOL:automatic] synonym: "endothelium of capillary vessel of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "endothelium of capillary vessel of respiratory system" EXACT [OBOL:automatic] synonym: "respiratory system blood capillary endothelium" EXACT [OBOL:automatic] synonym: "respiratory system capillary vessel endothelium" EXACT [OBOL:automatic] synonym: "respiratory system endothelium of blood capillary" EXACT [OBOL:automatic] synonym: "respiratory system endothelium of capillary" EXACT [OBOL:automatic] synonym: "respiratory system endothelium of capillary vessel" EXACT [OBOL:automatic] xref: EMAPA:37575 {source="MA:th"} xref: MA:0001808 is_a: UBERON:0001915 ! endothelium of capillary is_a: UBERON:0004702 ! respiratory system blood vessel endothelium intersection_of: UBERON:0001915 ! endothelium of capillary intersection_of: BFO:0000050 UBERON:0001004 ! part of respiratory system relationship: BFO:0000050 UBERON:0003526 ! part of respiratory system capillary [Term] id: UBERON:0003494 name: respiratory system venule namespace: uberon def: "A venule that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "apparatus respiratorius venule" EXACT [OBOL:automatic] synonym: "venule of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "venule of respiratory system" EXACT [OBOL:automatic] xref: EMAPA:37587 {source="MA:th"} xref: MA:0001813 is_a: UBERON:0001979 ! venule is_a: UBERON:0003504 ! respiratory system blood vessel intersection_of: UBERON:0001979 ! venule intersection_of: BFO:0000050 UBERON:0001004 ! part of respiratory system [Term] id: UBERON:0003495 name: respiratory system arteriole namespace: uberon def: "An arteriole that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:37568 {source="MA:th"} xref: MA:0001803 is_a: UBERON:0001980 ! arteriole is_a: UBERON:0003643 ! respiratory system arterial blood vessel intersection_of: UBERON:0001980 ! arteriole intersection_of: BFO:0000050 UBERON:0001004 ! part of respiratory system relationship: BFO:0000050 UBERON:0003469 ! part of respiratory system artery [Term] id: UBERON:0003496 name: head blood vessel namespace: uberon def: "A blood vessel that is part of a head [Automatically generated definition]." [OBOL:automatic] synonym: "adult head blood vessel" EXACT [OBOL:automatic] synonym: "blood vessel of adult head" EXACT [OBOL:automatic] synonym: "blood vessel of head" EXACT [OBOL:automatic] xref: EMAPA:36610 xref: MA:0000575 xref: SCTID:127865000 is_a: UBERON:0001981 ! blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: BFO:0000050 UBERON:0000033 ! part of head relationship: BFO:0000050 UBERON:0011362 ! part of cranial blood vasculature [Term] id: UBERON:0003497 name: abdomen blood vessel namespace: uberon def: "A blood vessel that is part of an abdomen [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of abdomen" EXACT [OBOL:automatic] xref: MA:0000518 is_a: UBERON:0003835 ! abdominal segment blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: BFO:0000050 UBERON:0000916 ! part of abdomen relationship: BFO:0000050 UBERON:0000916 ! part of abdomen [Term] id: UBERON:0003498 name: heart blood vessel namespace: uberon def: "A blood vessel that is part of a heart [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of heart" EXACT [OBOL:automatic] xref: EMAPA:35397 xref: MA:0002483 is_a: UBERON:0003834 ! thoracic segment blood vessel is_a: UBERON:0005985 ! coronary vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: BFO:0000050 UBERON:0000948 ! part of heart relationship: BFO:0000050 UBERON:0018674 ! part of heart vasculature [Term] id: UBERON:0003499 name: brain blood vessel namespace: uberon def: "A blood vessel that is part of a brain [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of brain" EXACT [OBOL:automatic] xref: EMAPA:35182 xref: MA:0002769 is_a: UBERON:0001981 ! blood vessel is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0001981 ! blood vessel intersection_of: BFO:0000050 UBERON:0000955 ! part of brain relationship: BFO:0000050 UBERON:0008998 ! part of vasculature of brain [Term] id: UBERON:0003500 name: corneal blood vessel namespace: uberon def: "A blood vessel that is part of a cornea [Automatically generated definition]." [https://orcid.org/0000-0002-6601-2165, https://sourceforge.net/tracker/index.php?func=detail&aid=3564332&group_id=36855&atid=440764] synonym: "blood vessel of cornea" EXACT [OBOL:automatic] synonym: "cornea blood vessel" EXACT [OBOL:automatic] xref: EMAPA:36611 xref: MA:0001241 is_a: UBERON:0003496 ! head blood vessel is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: UBERON:0001981 ! blood vessel intersection_of: BFO:0000050 UBERON:0000964 ! part of cornea relationship: BFO:0000050 UBERON:0000964 ! part of cornea [Term] id: UBERON:0003501 name: retina blood vessel namespace: uberon def: "A blood vessel that is part of a retina [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of inner layer of eyeball" EXACT [OBOL:automatic] synonym: "blood vessel of retina" EXACT [OBOL:automatic] synonym: "blood vessel of tunica interna of eyeball" EXACT [OBOL:automatic] synonym: "inner layer of eyeball blood vessel" EXACT [OBOL:automatic] synonym: "retinal blood vessel" EXACT [OBOL:automatic] synonym: "tunica interna of eyeball blood vessel" EXACT [OBOL:automatic] xref: EMAPA:36520 xref: GAID:509 xref: MA:0001317 xref: MESH:D012171 xref: SCTID:280692003 xref: XAO:0004153 is_a: UBERON:0003496 ! head blood vessel is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: UBERON:0001981 ! blood vessel intersection_of: BFO:0000050 UBERON:0000966 ! part of retina relationship: BFO:0000050 UBERON:0004864 ! part of vasculature of retina relationship: RO:0002433 UBERON:0000966 ! contributes to morphology of retina [Term] id: UBERON:0003502 name: neck blood vessel namespace: uberon def: "A blood vessel that is part of a neck [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of neck" EXACT [OBOL:automatic] synonym: "blood vessel of neck (volume)" EXACT [OBOL:automatic] synonym: "neck (volume) blood vessel" EXACT [OBOL:automatic] xref: EMAPA:37236 {source="MA:th"} xref: MA:0000583 is_a: UBERON:0001981 ! blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: BFO:0000050 UBERON:0000974 ! part of neck relationship: BFO:0000050 UBERON:0000974 ! part of neck [Term] id: UBERON:0003504 name: respiratory system blood vessel namespace: uberon def: "A blood vessel that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "apparatus respiratorius blood vessel" EXACT [OBOL:automatic] synonym: "blood vessel of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "blood vessel of respiratory system" EXACT [OBOL:automatic] xref: EMAPA:35731 xref: EMAPA:35995 xref: MA:0001799 is_a: UBERON:0001981 ! blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: BFO:0000050 UBERON:0001004 ! part of respiratory system relationship: BFO:0000050 UBERON:0001004 ! part of respiratory system [Term] id: UBERON:0003509 name: arterial blood vessel namespace: uberon def: "A blood vessel that is part of the arterial system. Includes artery, arteriole and aorta." [https://orcid.org/0000-0002-6601-2165] xref: EMAPA:35144 xref: MA:0000061 is_a: UBERON:0001981 ! blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: BFO:0000050 UBERON:0004572 ! part of arterial system relationship: BFO:0000050 UBERON:0004572 ! part of arterial system [Term] id: UBERON:0003511 name: iris blood vessel namespace: uberon def: "A blood vessel that is part of a iris [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of iris" EXACT [OBOL:automatic] xref: EMAPA:37387 {source="MA:th"} xref: MA:0001290 xref: ZFA:0005568 is_a: UBERON:0003496 ! head blood vessel is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: UBERON:0001981 ! blood vessel intersection_of: BFO:0000050 UBERON:0001769 ! part of iris relationship: BFO:0000050 UBERON:0004118 ! part of vasculature of iris [Term] id: UBERON:0003512 name: lung blood vessel namespace: uberon def: "A blood vessel that is part of a lung [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of lung" EXACT [OBOL:automatic] xref: EMAPA:32867 xref: MA:0002457 is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure is_a: UBERON:0003504 ! respiratory system blood vessel is_a: UBERON:0003834 ! thoracic segment blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: BFO:0000050 UBERON:0002048 ! part of lung relationship: BFO:0000050 UBERON:0002048 ! part of lung relationship: RO:0002433 UBERON:0002048 ! contributes to morphology of lung [Term] id: UBERON:0003513 name: trunk blood vessel namespace: uberon def: "A blood vessel that is part of a trunk [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of torso" EXACT [OBOL:automatic] synonym: "blood vessel of trunk" EXACT [OBOL:automatic] synonym: "torso blood vessel" EXACT [OBOL:automatic] xref: EMAPA:37237 {source="MA:th"} xref: MA:0000511 is_a: UBERON:0001981 ! blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: BFO:0000050 UBERON:0002100 ! part of trunk relationship: BFO:0000050 UBERON:0002100 ! part of trunk [Term] id: UBERON:0003517 name: kidney blood vessel namespace: uberon def: "A blood vessel that is part of a kidney [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of kidney" EXACT [OBOL:automatic] synonym: "renal blood vessel" EXACT [OBOL:automatic] xref: EMAPA:28457 xref: MA:0001682 xref: TAO:0005306 xref: ZFA:0005306 is_a: UBERON:0003497 ! abdomen blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: BFO:0000050 UBERON:0002113 ! part of kidney relationship: BFO:0000050 UBERON:0006544 ! part of kidney vasculature [Term] id: UBERON:0003519 name: thoracic cavity blood vessel namespace: uberon def: "A blood vessel that is part of a thoracic cavity [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of cavity of chest" EXACT [OBOL:automatic] synonym: "blood vessel of cavity of thorax" EXACT [OBOL:automatic] synonym: "blood vessel of chest cavity" EXACT [OBOL:automatic] synonym: "blood vessel of pectoral cavity" EXACT [OBOL:automatic] synonym: "blood vessel of thoracic cavity" EXACT [OBOL:automatic] synonym: "cavity of chest blood vessel" EXACT [OBOL:automatic] synonym: "cavity of thorax blood vessel" EXACT [OBOL:automatic] synonym: "chest cavity blood vessel" EXACT [OBOL:automatic] synonym: "pectoral cavity blood vessel" EXACT [OBOL:automatic] xref: EMAPA:37240 {source="MA:th"} xref: MA:0000554 is_a: UBERON:0001981 ! blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: RO:0001025 UBERON:0002224 ! located in thoracic cavity relationship: RO:0001025 UBERON:0002224 ! located in thoracic cavity [Term] id: UBERON:0003520 name: pelvis blood vessel namespace: uberon def: "A blood vessel that is part of a pelvis [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of pelvis" EXACT [OBOL:automatic] xref: EMAPA:37244 {source="MA:th"} xref: MA:0000531 is_a: UBERON:0003835 ! abdominal segment blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: BFO:0000050 UBERON:0002355 ! part of pelvic region of trunk relationship: BFO:0000050 UBERON:0002355 ! part of pelvic region of trunk [Term] id: UBERON:0003524 name: tail blood vessel namespace: uberon def: "A blood vessel that is part of a tail [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of post-vent region" EXACT [OBOL:automatic] synonym: "blood vessel of tail" EXACT [OBOL:automatic] synonym: "post-vent region blood vessel" EXACT [OBOL:automatic] xref: EMAPA:35848 xref: MA:0000695 is_a: UBERON:0001981 ! blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: BFO:0000050 UBERON:0007812 ! part of post-anal tail relationship: BFO:0000050 UBERON:0007812 ! part of post-anal tail [Term] id: UBERON:0003526 name: respiratory system capillary namespace: uberon def: "A capillary that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "apparatus respiratorius blood capillary" EXACT [OBOL:automatic] synonym: "apparatus respiratorius capillary" EXACT [OBOL:automatic] synonym: "apparatus respiratorius capillary vessel" EXACT [OBOL:automatic] synonym: "blood capillary of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "blood capillary of respiratory system" EXACT [OBOL:automatic] synonym: "capillary of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "capillary of respiratory system" EXACT [OBOL:automatic] synonym: "capillary vessel of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "capillary vessel of respiratory system" EXACT [OBOL:automatic] synonym: "respiratory system blood capillary" EXACT [OBOL:automatic] synonym: "respiratory system capillary vessel" EXACT [OBOL:automatic] xref: EMAPA:37574 {source="MA:th"} xref: MA:0001807 is_a: UBERON:0001982 ! capillary is_a: UBERON:0003504 ! respiratory system blood vessel intersection_of: UBERON:0001982 ! capillary intersection_of: BFO:0000050 UBERON:0001004 ! part of respiratory system [Term] id: UBERON:0003527 name: kidney capillary namespace: uberon def: "A capillary that is part of a kidney [Automatically generated definition]." [OBOL:automatic] synonym: "blood capillary of kidney" EXACT [OBOL:automatic] synonym: "capillary of kidney" EXACT [OBOL:automatic] synonym: "capillary vessel of kidney" EXACT [OBOL:automatic] synonym: "kidney blood capillary" EXACT [OBOL:automatic] synonym: "kidney capillary vessel" EXACT [OBOL:automatic] synonym: "renal capillary" EXACT [OBOL:automatic] xref: EMAPA:31443 xref: MA:0002586 xref: SCTID:275409003 is_a: UBERON:0001982 ! capillary is_a: UBERON:0003517 ! kidney blood vessel intersection_of: UBERON:0001982 ! capillary intersection_of: BFO:0000050 UBERON:0002113 ! part of kidney [Term] id: UBERON:0003528 name: brain gray matter namespace: uberon def: "A gray matter that is part of a brain [Automatically generated definition]." [OBOL:automatic] synonym: "brain grey matter" EXACT [MA:0000810] synonym: "brain grey substance" EXACT [OBOL:automatic] synonym: "gray matter of brain" EXACT [OBOL:automatic] synonym: "grey matter of brain" EXACT [OBOL:automatic] synonym: "grey substance of brain" EXACT [OBOL:automatic] xref: EMAPA:35184 xref: MA:0000810 xref: NCIT:C49333 xref: UMLS:C1707348 {source="ncithesaurus:Cerebral_Gray_Matter"} is_a: UBERON:0002020 ! gray matter intersection_of: UBERON:0002020 ! gray matter intersection_of: BFO:0000050 UBERON:0000955 ! part of brain relationship: BFO:0000050 UBERON:0000955 ! part of brain [Term] id: UBERON:0003534 name: tail skin namespace: uberon def: "A zone of skin that is part of a tail [Automatically generated definition]." [OBOL:automatic] synonym: "post-vent region skin" EXACT [OBOL:automatic] synonym: "skin of post-vent region" EXACT [OBOL:automatic] synonym: "skin of tail" EXACT [OBOL:automatic] xref: EMAPA:36502 xref: MA:0000700 xref: SCTID:67214004 is_a: UBERON:0000014 ! zone of skin intersection_of: UBERON:0000014 ! zone of skin intersection_of: BFO:0000050 UBERON:0007812 ! part of post-anal tail relationship: BFO:0000050 UBERON:0007812 ! part of post-anal tail [Term] id: UBERON:0003566 name: head connective tissue namespace: uberon def: "A portion of connective tissue that is part of a head [Automatically generated definition]." [OBOL:automatic] synonym: "adult head connective tissue" EXACT [OBOL:automatic] synonym: "adult head portion of connective tissue" EXACT [OBOL:automatic] synonym: "adult head textus connectivus" EXACT [OBOL:automatic] synonym: "connective tissue of adult head" EXACT [OBOL:automatic] synonym: "connective tissue of head" EXACT [OBOL:automatic] synonym: "head portion of connective tissue" EXACT [OBOL:automatic] synonym: "head textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of adult head" EXACT [OBOL:automatic] synonym: "portion of connective tissue of head" EXACT [OBOL:automatic] synonym: "textus connectivus of adult head" EXACT [OBOL:automatic] synonym: "textus connectivus of head" EXACT [OBOL:automatic] xref: EMAPA:16098 xref: MA:0000577 is_a: UBERON:0002384 ! connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: BFO:0000050 UBERON:0000033 ! part of head relationship: BFO:0000050 UBERON:0000033 ! part of head relationship: RO:0002494 UBERON:0005253 ! transformation of head mesenchyme [Term] id: UBERON:0003567 name: abdomen connective tissue namespace: uberon def: "A portion of connective tissue that is part of an abdomen [Automatically generated definition]." [OBOL:automatic] synonym: "abdomen portion of connective tissue" EXACT [OBOL:automatic] synonym: "abdomen textus connectivus" EXACT [OBOL:automatic] synonym: "connective tissue of abdomen" EXACT [OBOL:automatic] synonym: "portion of connective tissue of abdomen" EXACT [OBOL:automatic] synonym: "textus connectivus of abdomen" EXACT [OBOL:automatic] xref: MA:0000519 is_a: UBERON:0003838 ! abdominal segment connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: BFO:0000050 UBERON:0000916 ! part of abdomen relationship: BFO:0000050 UBERON:0000916 ! part of abdomen [Term] id: UBERON:0003568 name: neck connective tissue namespace: uberon def: "A portion of connective tissue that is part of a neck [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of neck" EXACT [OBOL:automatic] synonym: "connective tissue of neck (volume)" EXACT [OBOL:automatic] synonym: "neck (volume) connective tissue" EXACT [OBOL:automatic] synonym: "neck (volume) portion of connective tissue" EXACT [OBOL:automatic] synonym: "neck (volume) textus connectivus" EXACT [OBOL:automatic] synonym: "neck portion of connective tissue" EXACT [OBOL:automatic] synonym: "neck textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of neck" EXACT [OBOL:automatic] synonym: "portion of connective tissue of neck (volume)" EXACT [OBOL:automatic] synonym: "textus connectivus of neck" EXACT [OBOL:automatic] synonym: "textus connectivus of neck (volume)" EXACT [OBOL:automatic] xref: EMAPA:37250 {source="MA:th"} xref: MA:0000585 is_a: UBERON:0002384 ! connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: BFO:0000050 UBERON:0000974 ! part of neck relationship: BFO:0000050 UBERON:0000974 ! part of neck [Term] id: UBERON:0003570 name: respiratory system connective tissue namespace: uberon def: "A portion of connective tissue that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "apparatus respiratorius connective tissue" EXACT [OBOL:automatic] synonym: "apparatus respiratorius portion of connective tissue" EXACT [OBOL:automatic] synonym: "apparatus respiratorius textus connectivus" EXACT [OBOL:automatic] synonym: "connective tissue of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "connective tissue of respiratory system" EXACT [OBOL:automatic] synonym: "portion of connective tissue of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "portion of connective tissue of respiratory system" EXACT [OBOL:automatic] synonym: "respiratory system portion of connective tissue" EXACT [OBOL:automatic] synonym: "respiratory system textus connectivus" EXACT [OBOL:automatic] synonym: "textus connectivus of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "textus connectivus of respiratory system" EXACT [OBOL:automatic] xref: EMAPA:35968 xref: EMAPA:35977 xref: MA:0001814 is_a: UBERON:0002384 ! connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: BFO:0000050 UBERON:0001004 ! part of respiratory system relationship: BFO:0000050 UBERON:0001004 ! part of respiratory system [Term] id: UBERON:0003580 name: lower respiratory tract connective tissue namespace: uberon def: "A portion of connective tissue that is part of a lower respiratory tract [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of lower respiratory tract" EXACT [OBOL:automatic] synonym: "lower respiratory tract portion of connective tissue" EXACT [OBOL:automatic] synonym: "lower respiratory tract textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of lower respiratory tract" EXACT [OBOL:automatic] synonym: "textus connectivus of lower respiratory tract" EXACT [OBOL:automatic] xref: EMAPA:37548 {source="MA:th"} xref: MA:0002409 is_a: UBERON:0003570 ! respiratory system connective tissue is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: UBERON:0002384 ! connective tissue intersection_of: BFO:0000050 UBERON:0001558 ! part of lower respiratory tract relationship: BFO:0000050 UBERON:0001558 ! part of lower respiratory tract [Term] id: UBERON:0003585 name: dermis connective tissue namespace: uberon def: "A portion of connective tissue that is part of a dermis [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of dermis" EXACT [OBOL:automatic] synonym: "dermis portion of connective tissue" EXACT [OBOL:automatic] synonym: "dermis textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of dermis" EXACT [OBOL:automatic] synonym: "textus connectivus of dermis" EXACT [OBOL:automatic] xref: EMAPA:36509 xref: MA:0000799 is_a: UBERON:0002384 ! connective tissue is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: UBERON:0002384 ! connective tissue intersection_of: BFO:0000050 UBERON:0002067 ! part of dermis relationship: BFO:0000050 UBERON:0002067 ! part of dermis relationship: RO:0002202 UBERON:0004016 ! develops from dermatome [Term] id: UBERON:0003586 name: trunk connective tissue namespace: uberon def: "A portion of connective tissue that is part of a trunk [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of torso" EXACT [OBOL:automatic] synonym: "connective tissue of trunk" EXACT [OBOL:automatic] synonym: "portion of connective tissue of torso" EXACT [OBOL:automatic] synonym: "portion of connective tissue of trunk" EXACT [OBOL:automatic] synonym: "textus connectivus of torso" EXACT [OBOL:automatic] synonym: "textus connectivus of trunk" EXACT [OBOL:automatic] synonym: "torso connective tissue" EXACT [OBOL:automatic] synonym: "torso portion of connective tissue" EXACT [OBOL:automatic] synonym: "torso textus connectivus" EXACT [OBOL:automatic] synonym: "trunk portion of connective tissue" EXACT [OBOL:automatic] synonym: "trunk textus connectivus" EXACT [OBOL:automatic] xref: EMAPA:37252 {source="MA:th"} xref: MA:0000513 is_a: UBERON:0002384 ! connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: BFO:0000050 UBERON:0002100 ! part of trunk relationship: BFO:0000050 UBERON:0002100 ! part of trunk [Term] id: UBERON:0003593 name: thoracic cavity connective tissue namespace: uberon def: "A portion of connective tissue that is part of a thoracic cavity [Automatically generated definition]." [OBOL:automatic] synonym: "cavity of chest connective tissue" EXACT [OBOL:automatic] synonym: "cavity of chest portion of connective tissue" EXACT [OBOL:automatic] synonym: "cavity of chest textus connectivus" EXACT [OBOL:automatic] synonym: "cavity of thorax connective tissue" EXACT [OBOL:automatic] synonym: "cavity of thorax portion of connective tissue" EXACT [OBOL:automatic] synonym: "cavity of thorax textus connectivus" EXACT [OBOL:automatic] synonym: "chest cavity connective tissue" EXACT [OBOL:automatic] synonym: "chest cavity portion of connective tissue" EXACT [OBOL:automatic] synonym: "chest cavity textus connectivus" EXACT [OBOL:automatic] synonym: "connective tissue of cavity of chest" EXACT [OBOL:automatic] synonym: "connective tissue of cavity of thorax" EXACT [OBOL:automatic] synonym: "connective tissue of chest cavity" EXACT [OBOL:automatic] synonym: "connective tissue of pectoral cavity" EXACT [OBOL:automatic] synonym: "connective tissue of thoracic cavity" EXACT [OBOL:automatic] synonym: "pectoral cavity connective tissue" EXACT [OBOL:automatic] synonym: "pectoral cavity portion of connective tissue" EXACT [OBOL:automatic] synonym: "pectoral cavity textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of cavity of chest" EXACT [OBOL:automatic] synonym: "portion of connective tissue of cavity of thorax" EXACT [OBOL:automatic] synonym: "portion of connective tissue of chest cavity" EXACT [OBOL:automatic] synonym: "portion of connective tissue of pectoral cavity" EXACT [OBOL:automatic] synonym: "portion of connective tissue of thoracic cavity" EXACT [OBOL:automatic] synonym: "textus connectivus of cavity of chest" EXACT [OBOL:automatic] synonym: "textus connectivus of cavity of thorax" EXACT [OBOL:automatic] synonym: "textus connectivus of chest cavity" EXACT [OBOL:automatic] synonym: "textus connectivus of pectoral cavity" EXACT [OBOL:automatic] synonym: "textus connectivus of thoracic cavity" EXACT [OBOL:automatic] synonym: "thoracic cavity portion of connective tissue" EXACT [OBOL:automatic] synonym: "thoracic cavity textus connectivus" EXACT [OBOL:automatic] xref: EMAPA:37255 {source="MA:th"} xref: MA:0000555 is_a: UBERON:0002384 ! connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: RO:0001025 UBERON:0002224 ! located in thoracic cavity relationship: RO:0001025 UBERON:0002224 ! located in thoracic cavity [Term] id: UBERON:0003594 name: pelvis connective tissue namespace: uberon def: "A portion of connective tissue that is part of a pelvis [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of pelvis" EXACT [OBOL:automatic] synonym: "pelvis portion of connective tissue" EXACT [OBOL:automatic] synonym: "pelvis textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of pelvis" EXACT [OBOL:automatic] synonym: "textus connectivus of pelvis" EXACT [OBOL:automatic] xref: EMAPA:37257 {source="MA:th"} xref: MA:0000533 is_a: UBERON:0003838 ! abdominal segment connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: BFO:0000050 UBERON:0002355 ! part of pelvic region of trunk relationship: BFO:0000050 UBERON:0002355 ! part of pelvic region of trunk [Term] id: UBERON:0003599 name: tail connective tissue namespace: uberon def: "A portion of connective tissue that is part of a tail [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of post-vent region" EXACT [OBOL:automatic] synonym: "connective tissue of tail" EXACT [OBOL:automatic] synonym: "portion of connective tissue of post-vent region" EXACT [OBOL:automatic] synonym: "portion of connective tissue of tail" EXACT [OBOL:automatic] synonym: "post-vent region connective tissue" EXACT [OBOL:automatic] synonym: "post-vent region portion of connective tissue" EXACT [OBOL:automatic] synonym: "post-vent region textus connectivus" EXACT [OBOL:automatic] synonym: "tail portion of connective tissue" EXACT [OBOL:automatic] synonym: "tail textus connectivus" EXACT [OBOL:automatic] synonym: "textus connectivus of post-vent region" EXACT [OBOL:automatic] synonym: "textus connectivus of tail" EXACT [OBOL:automatic] xref: EMAPA:16749 xref: MA:0000697 is_a: UBERON:0002384 ! connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: BFO:0000050 UBERON:0007812 ! part of post-anal tail relationship: BFO:0000050 UBERON:0007812 ! part of post-anal tail [Term] id: UBERON:0003601 name: neck cartilage namespace: uberon def: "A cartilage that is part of a neck [Automatically generated definition]." [OBOL:automatic] synonym: "cartilage of neck" EXACT [OBOL:automatic] synonym: "cartilage of neck (volume)" EXACT [OBOL:automatic] synonym: "neck (volume) cartilage" EXACT [OBOL:automatic] xref: EMAPA:37251 {source="MA:th"} xref: MA:0000586 is_a: UBERON:0007844 ! cartilage element intersection_of: UBERON:0007844 ! cartilage element intersection_of: BFO:0000050 UBERON:0000974 ! part of neck relationship: BFO:0000050 UBERON:0000974 ! part of neck [Term] id: UBERON:0003603 name: lower respiratory tract cartilage namespace: uberon def: "A cartilage that is part of a lower respiratory tract [Automatically generated definition]." [OBOL:automatic] synonym: "cartilage of lower respiratory tract" EXACT [OBOL:automatic] xref: EMAPA:37547 {source="MA:th"} xref: MA:0001819 xref: NCIT:C49256 xref: UMLS:C1708759 {source="ncithesaurus:Lower_Respiratory_Tract_Cartilage"} is_a: UBERON:0003406 ! cartilage of respiratory system is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: UBERON:0007844 ! cartilage element intersection_of: BFO:0000050 UBERON:0001558 ! part of lower respiratory tract relationship: BFO:0000050 UBERON:0001558 ! part of lower respiratory tract [Term] id: UBERON:0003605 name: eye skin gland namespace: uberon def: "A skin gland that is part of a camera-type eye [Automatically generated definition]." [OBOL:automatic] synonym: "camera-type eye skin gland" EXACT [OBOL:automatic] synonym: "camera-type eye skin glands" EXACT [OBOL:automatic] synonym: "camera-type eye skin glands set" EXACT [OBOL:automatic] synonym: "skin gland of camera-type eye" EXACT [OBOL:automatic] synonym: "skin gland of vertebrate eye" EXACT [OBOL:automatic] synonym: "skin glands of camera-type eye" EXACT [OBOL:automatic] synonym: "skin glands of vertebrate eye" EXACT [OBOL:automatic] synonym: "skin glands set of camera-type eye" EXACT [OBOL:automatic] synonym: "skin glands set of vertebrate eye" EXACT [OBOL:automatic] synonym: "vertebrate eye skin gland" EXACT [OBOL:automatic] synonym: "vertebrate eye skin glands" EXACT [OBOL:automatic] synonym: "vertebrate eye skin glands set" EXACT [OBOL:automatic] xref: EMAPA:37530 {source="MA:th"} xref: MA:0002451 is_a: UBERON:0002419 ! skin gland is_a: UBERON:0004859 ! eye gland is_a: UBERON:0015152 ! gland of ocular region intersection_of: UBERON:0002419 ! skin gland intersection_of: BFO:0000050 UBERON:0000019 ! part of camera-type eye relationship: BFO:0000050 UBERON:0000019 ! part of camera-type eye [Term] id: UBERON:0003609 name: aorta elastic tissue namespace: uberon def: "The dense connective tissue which contains predominantly elastic fibers and is found in the tunica media of the aorta wall." [MP:0009862] synonym: "adult aorta elastic connective tissue" EXACT [OBOL:automatic] synonym: "adult aorta elastic tissue" EXACT [OBOL:automatic] synonym: "adult aorta textus connectivus elasticus" EXACT [OBOL:automatic] synonym: "aorta elastic connective tissue" EXACT [OBOL:automatic] synonym: "aorta elastic lamina" EXACT [MP:0009862] synonym: "aorta textus connectivus elasticus" EXACT [OBOL:automatic] synonym: "dorsal aorta elastic connective tissue" EXACT [OBOL:automatic] synonym: "dorsal aorta elastic tissue" EXACT [OBOL:automatic] synonym: "dorsal aorta textus connectivus elasticus" EXACT [OBOL:automatic] synonym: "elastic connective tissue of adult aorta" EXACT [OBOL:automatic] synonym: "elastic connective tissue of aorta" EXACT [OBOL:automatic] synonym: "elastic connective tissue of dorsal aorta" EXACT [OBOL:automatic] synonym: "elastic connective tissue of trunk of aortic tree" EXACT [OBOL:automatic] synonym: "elastic tissue of adult aorta" EXACT [OBOL:automatic] synonym: "elastic tissue of aorta" EXACT [OBOL:automatic] synonym: "elastic tissue of dorsal aorta" EXACT [OBOL:automatic] synonym: "elastic tissue of trunk of aortic tree" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of adult aorta" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of aorta" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of dorsal aorta" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of trunk of aortic tree" EXACT [OBOL:automatic] synonym: "trunk of aortic tree elastic connective tissue" EXACT [OBOL:automatic] synonym: "trunk of aortic tree elastic tissue" EXACT [OBOL:automatic] synonym: "trunk of aortic tree textus connectivus elasticus" EXACT [OBOL:automatic] xref: MA:0002859 is_a: UBERON:0003614 ! blood vessel elastic tissue intersection_of: UBERON:0002521 ! elastic tissue intersection_of: BFO:0000050 UBERON:0000947 ! part of aorta relationship: BFO:0000050 UBERON:0000947 ! part of aorta [Term] id: UBERON:0003610 name: heart elastic tissue namespace: uberon def: "The type of heart connective tissue found in the endocardial layer that consists mainly of elastic fibers." [MP:0009863] synonym: "cardiac elastic tissue" EXACT [MP:0009863] synonym: "elastic connective tissue of heart" EXACT [OBOL:automatic] synonym: "elastic tissue of heart" EXACT [OBOL:automatic] synonym: "heart elastic connective tissue" EXACT [OBOL:automatic] synonym: "heart textus connectivus elasticus" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of heart" EXACT [OBOL:automatic] xref: MA:0002858 is_a: UBERON:0003613 ! cardiovascular system elastic tissue is_a: UBERON:0003837 ! thoracic segment connective tissue is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0002521 ! elastic tissue intersection_of: BFO:0000050 UBERON:0000948 ! part of heart relationship: BFO:0000050 UBERON:0000948 ! part of heart [Term] id: UBERON:0003611 name: respiratory system elastic tissue namespace: uberon def: "An elastic tissue that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "apparatus respiratorius elastic connective tissue" EXACT [OBOL:automatic] synonym: "apparatus respiratorius elastic tissue" EXACT [OBOL:automatic] synonym: "apparatus respiratorius textus connectivus elasticus" EXACT [OBOL:automatic] synonym: "elastic connective tissue of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "elastic connective tissue of respiratory system" EXACT [OBOL:automatic] synonym: "elastic tissue of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "elastic tissue of respiratory system" EXACT [OBOL:automatic] synonym: "respiratory system elastic connective tissue" EXACT [OBOL:automatic] synonym: "respiratory system textus connectivus elasticus" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of respiratory system" EXACT [OBOL:automatic] xref: EMAPA:37579 {source="MA:th"} xref: MA:0001820 is_a: UBERON:0002521 ! elastic tissue is_a: UBERON:0003570 ! respiratory system connective tissue intersection_of: UBERON:0002521 ! elastic tissue intersection_of: BFO:0000050 UBERON:0001004 ! part of respiratory system relationship: BFO:0000050 UBERON:0004777 ! part of respiratory system submucosa [Term] id: UBERON:0003613 name: cardiovascular system elastic tissue namespace: uberon def: "An elastic tissue that is part of a circulatory system [Automatically generated definition]." [OBOL:automatic] synonym: "cardiovascular system elastic connective tissue" EXACT [OBOL:automatic] synonym: "cardiovascular system textus connectivus elasticus" EXACT [OBOL:automatic] synonym: "circulatory system elastic connective tissue" EXACT [OBOL:automatic] synonym: "circulatory system elastic tissue" EXACT [OBOL:automatic] synonym: "circulatory system textus connectivus elasticus" EXACT [OBOL:automatic] synonym: "elastic connective tissue of cardiovascular system" EXACT [OBOL:automatic] synonym: "elastic connective tissue of circulatory system" EXACT [OBOL:automatic] synonym: "elastic tissue of cardiovascular system" EXACT [OBOL:automatic] synonym: "elastic tissue of circulatory system" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of cardiovascular system" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of circulatory system" EXACT [OBOL:automatic] xref: MA:0002857 is_a: UBERON:0002521 ! elastic tissue intersection_of: UBERON:0002521 ! elastic tissue intersection_of: BFO:0000050 UBERON:0001009 ! part of circulatory system relationship: BFO:0000050 UBERON:0004535 ! part of cardiovascular system [Term] id: UBERON:0003614 name: blood vessel elastic tissue namespace: uberon def: "Elastic tissue layer that lines a blood vessel layer." [http://orcid.org/0000-0002-6601-2165, https://sourceforge.net/p/obo/mammalian-phenotype-requests/2026/] synonym: "blood vessel elastic connective tissue" EXACT [OBOL:automatic] synonym: "blood vessel textus connectivus elasticus" EXACT [OBOL:automatic] synonym: "elastic connective tissue of blood vessel" EXACT [OBOL:automatic] synonym: "elastic tissue of blood vessel" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of blood vessel" EXACT [OBOL:automatic] synonym: "vascular elastic lamina" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "vascular elastic tissue" EXACT [MP:0006083] xref: EMAPA:36300 xref: MA:0002856 is_a: UBERON:0003613 ! cardiovascular system elastic tissue is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0002521 ! elastic tissue intersection_of: BFO:0000050 UBERON:0001981 ! part of blood vessel relationship: BFO:0000050 UBERON:0001981 ! part of blood vessel [Term] id: UBERON:0003615 name: lung elastic tissue namespace: uberon def: "Elastic tissue that is part of a lung [Automatically generated definition]." [OBOL:automatic] synonym: "elastic connective tissue of lung" EXACT [OBOL:automatic] synonym: "elastic tissue of lung" EXACT [OBOL:automatic] synonym: "lung elastic connective tissue" EXACT [OBOL:automatic] synonym: "lung textus connectivus elasticus" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of lung" EXACT [OBOL:automatic] xref: MA:0002860 is_a: UBERON:0000114 ! lung connective tissue is_a: UBERON:0003611 ! respiratory system elastic tissue intersection_of: UBERON:0002521 ! elastic tissue intersection_of: BFO:0000050 UBERON:0002048 ! part of lung [Term] id: UBERON:0003618 name: aorta tunica media namespace: uberon def: "The middle layer of the aorta wall, containing the smooth muscle layer and elastic fibers." [MP:0009873] synonym: "adult aorta tunica media" EXACT [OBOL:automatic] synonym: "dorsal aorta tunica media" EXACT [OBOL:automatic] synonym: "trunk of aortic tree tunica media" EXACT [OBOL:automatic] synonym: "tunica media of adult aorta" EXACT [OBOL:automatic] synonym: "tunica media of aorta" EXACT [OBOL:automatic] synonym: "tunica media of dorsal aorta" EXACT [OBOL:automatic] synonym: "tunica media of trunk of aortic tree" EXACT [OBOL:automatic] xref: EMAPA:35138 xref: FMA:74433 xref: MA:0002903 xref: SCTID:48467007 is_a: UBERON:0002522 ! tunica media intersection_of: UBERON:0002522 ! tunica media intersection_of: BFO:0000050 UBERON:0000947 ! part of aorta relationship: BFO:0000050 UBERON:0004663 ! part of aorta wall relationship: RO:0002433 UBERON:0004663 ! contributes to morphology of aorta wall [Term] id: UBERON:0003619 name: aorta tunica intima namespace: uberon def: "The innermost layer of the aorta, containing the endothelium and an inner elastic membrane." [MP:0009872] synonym: "adult aorta tunica intima" EXACT [OBOL:automatic] synonym: "dorsal aorta tunica intima" EXACT [OBOL:automatic] synonym: "trunk of aortic tree tunica intima" EXACT [OBOL:automatic] synonym: "tunica intima of adult aorta" EXACT [OBOL:automatic] synonym: "tunica intima of aorta" EXACT [OBOL:automatic] synonym: "tunica intima of dorsal aorta" EXACT [OBOL:automatic] synonym: "tunica intima of trunk of aortic tree" EXACT [OBOL:automatic] xref: BTO:0005553 xref: EMAPA:35137 xref: FMA:74419 xref: MA:0002904 xref: SCTID:362031007 is_a: UBERON:0002523 ! tunica intima is_a: UBERON:0004797 ! blood vessel layer intersection_of: UBERON:0002523 ! tunica intima intersection_of: BFO:0000050 UBERON:0000947 ! part of aorta relationship: BFO:0000050 UBERON:0004663 ! part of aorta wall relationship: RO:0002433 UBERON:0004663 ! contributes to morphology of aorta wall [Term] id: UBERON:0003643 name: respiratory system arterial blood vessel namespace: uberon def: "An arterial blood vessel that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:37565 {source="MA:th"} xref: MA:0001800 is_a: UBERON:0003504 ! respiratory system blood vessel is_a: UBERON:0003509 ! arterial blood vessel intersection_of: UBERON:0003509 ! arterial blood vessel intersection_of: BFO:0000050 UBERON:0001004 ! part of respiratory system [Term] id: UBERON:0003644 name: kidney arterial blood vessel namespace: uberon def: "An arterial blood vessel that is part of a kidney [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:31436 xref: MA:0002578 is_a: UBERON:0003509 ! arterial blood vessel is_a: UBERON:0003517 ! kidney blood vessel intersection_of: UBERON:0003509 ! arterial blood vessel intersection_of: BFO:0000050 UBERON:0002113 ! part of kidney [Term] id: UBERON:0003665 name: post-anal tail muscle namespace: uberon def: "A muscle organ that attaches to a tail vertebra [Automatically generated definition]." [OBOL:automatic] synonym: "caudal muscle" EXACT [] synonym: "muscle organ of post-vent region" EXACT [OBOL:automatic] synonym: "muscle organ of tail" EXACT [OBOL:automatic] synonym: "post-vent region muscle organ" EXACT [OBOL:automatic] synonym: "tail muscle" EXACT [MA:0000699] synonym: "tail muscle organ" EXACT [OBOL:automatic] xref: AAO:0000081 xref: BTO:0001905 xref: EMAPA:37759 {source="MA:th"} xref: MA:0000699 xref: SCTID:113230005 is_a: UBERON:0004518 ! muscle of vertebral column intersection_of: UBERON:0014892 ! skeletal muscle organ, vertebrate intersection_of: RO:0002371 UBERON:0001095 ! attached to caudal vertebra relationship: RO:0002131 UBERON:0007812 ! overlaps post-anal tail relationship: RO:0002371 UBERON:0001095 ! attached to caudal vertebra [Term] id: UBERON:0003684 name: abdominal cavity namespace: uberon def: "The part of the ventral body cavity that is within the abdomen proper (excluding the pelvic cavity)." [UBERON:cjm] synonym: "cavity of abdominal compartment" EXACT [FMA:12266] synonym: "cavity of compartment of abdomen" EXACT [FMA:12266] synonym: "space of abdominal compartment" EXACT [FMA:12266] xref: EFO:0000213 xref: EMAPA:36505 xref: FMA:12266 xref: GAID:17 xref: galen:AbdominalCavity xref: MA:0003057 xref: MESH:D034841 xref: NCIT:C12664 xref: SCTID:361294009 xref: UMLS:C0230168 {source="ncithesaurus:Abdominal_Cavity"} xref: Wikipedia:Abdominal_cavity is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: BFO:0000050 UBERON:0002323 ! part of coelemic cavity lumen intersection_of: RO:0002572 UBERON:0000916 ! luminal space of abdomen relationship: BFO:0000050 UBERON:0035819 ! part of abdominopelvic cavity relationship: RO:0002572 UBERON:0000916 ! luminal space of abdomen property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/e/ee/Scheme_body_cavities-en.svg" xsd:anyURI [Term] id: UBERON:0003687 name: foramen magnum namespace: uberon def: "In anatomy, in the occipital bone, the foramen magnum is one of the several oval or circular apertures in the base of the skull, through which the medulla oblongata (an extension of the spinal cord) enters and exits the skull vault. Apart from the transmission of the medulla oblongata and its membranes, the foramen magnum transmits the Spinal Accessory nerve, vertebral arteries, the anterior and posterior spinal arteries, the membrana tectoria and alar ligaments. [WP,unvetted]." [Wikipedia:Foramen_magnum] xref: AAO:0010826 xref: EMAPA:37868 {source="MA:th"} xref: FMA:75306 xref: GAID:228 xref: MESH:D005539 xref: NCIT:C12495 xref: SCTID:244679008 xref: TAO:0002045 xref: UMLS:C0016519 {source="ncithesaurus:Foramen_Magnum"} xref: Wikipedia:Foramen_magnum xref: ZFA:0005387 is_a: UBERON:0013685 ! foramen of skull intersection_of: UBERON:0013685 ! foramen of skull intersection_of: RO:0002570 UBERON:0001896 ! conduit for medulla oblongata relationship: RO:0001025 UBERON:0001676 ! located in occipital bone relationship: RO:0002570 UBERON:0001896 ! conduit for medulla oblongata property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/3/39/Gray130.png" xsd:anyURI [Term] id: UBERON:0003694 name: atlanto-axial joint namespace: uberon def: "The Atlanto-axial joint is of a complicated nature, comprising no fewer than four distinct joints. There is a pivot articulation between the odontoid process of the axis and the ring formed by the anterior arch and the transverse ligament of the atlas." [Wikipedia:Atlanto-axial_joint] synonym: "atlanto axial joint" EXACT [GAID:250] synonym: "atlantoaxial joint" EXACT [GAID:250] xref: FMA:25524 xref: GAID:250 xref: MESH:D001268 xref: NCIT:C32157 xref: SCTID:361832004 xref: UMLS:C0004168 {source="ncithesaurus:Atlanto-axial_Joint"} xref: Wikipedia:Atlanto-axial_joint is_a: UBERON:0000982 ! skeletal joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: RO:0002176 UBERON:0001092 ! connects vertebral bone 1 intersection_of: RO:0002176 UBERON:0001093 ! connects vertebral bone 2 relationship: BFO:0000050 UBERON:0011138 ! part of postcranial axial skeletal system relationship: RO:0002176 UBERON:0001092 ! connects vertebral bone 1 relationship: RO:0002176 UBERON:0001093 ! connects vertebral bone 2 property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/d/d4/Gray304.png" xsd:anyURI [Term] id: UBERON:0003697 name: abdominal wall namespace: uberon def: "The tissues that surround the organs that are present within the abdominal cavity. The abdominal wall tissue is composed of layers of fat, parietal peritoneum, fascia, and muscles." [ncithesaurus:Abdominal_Wall] synonym: "paries abdominalis" EXACT [Wikipedia:Abdominal_wall] synonym: "wall of abdomen" EXACT [FMA:259054] synonym: "wall of abdomen proper" EXACT [FMA:10429] xref: EMAPA:37064 {source="MA:th"} xref: FMA:10429 xref: FMA:259054 xref: GAID:26 xref: MESH:D034861 xref: NCIT:C77608 xref: SCTID:181613000 xref: UMLS:C0836916 {source="ncithesaurus:Abdominal_Wall"} xref: Wikipedia:Abdominal_wall is_a: UBERON:0000060 ! anatomical wall intersection_of: UBERON:0000060 ! anatomical wall intersection_of: BFO:0000050 UBERON:0000916 ! part of abdomen relationship: BFO:0000050 UBERON:0000916 ! part of abdomen property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/e/ee/Scheme_body_cavities-en.svg" xsd:anyURI [Term] id: UBERON:0003703 name: extrahepatic bile duct namespace: uberon def: "Passages external to the liver for the conveyance of bile. These include the common bile duct and the common hepatic duct." [MESH:A03.159.183.079] xref: FMA:14678 xref: GAID:281 xref: MA:0002659 xref: MESH:D017734 xref: NCIT:C32573 xref: SCTID:276158002 xref: UMLS:C0206187 {source="ncithesaurus:Extrahepatic_Bile_Duct"} is_a: UBERON:0002394 ! bile duct [Term] id: UBERON:0003704 name: intrahepatic bile duct namespace: uberon def: "Passages within the liver for the conveyance of bile. Includes right and left hepatic ducts even though these may join outside the liver to form the common hepatic duct." [MESH:A03.159.183.158] synonym: "bile duct intrahepatic part" EXACT [MA:0001630] xref: FMA:15766 xref: GAID:287 xref: MA:0001630 xref: MESH:D001653 xref: NCIT:C12677 xref: SCTID:362193005 xref: TAO:0005169 xref: UMLS:C0005401 {source="ncithesaurus:Intrahepatic_Bile_Duct"} xref: ZFA:0005169 is_a: UBERON:0002394 {source="FMA"} ! bile duct intersection_of: UBERON:0002394 ! bile duct intersection_of: BFO:0000050 UBERON:0002107 ! part of liver relationship: BFO:0000050 UBERON:0002107 {source="MA"} ! part of liver relationship: RO:0002433 UBERON:0002107 ! contributes to morphology of liver [Term] id: UBERON:0003711 name: brachiocephalic vein namespace: uberon def: "The left and right brachiocephalic veins in the upper chest are formed by the union of each corresponding internal jugular vein and subclavian vein. This is at the level of the sternoclavicular joint. These great vessels merge to form the superior vena cava. The brachiocephalic veins are the major veins returning blood to the superior vena cava." [Wikipedia:Brachiocephalic_vein] synonym: "brachiocephalic venous tree" EXACT [FMA:4723] synonym: "innominate vein" EXACT [FMA:4723] xref: EHDAA2:0000182 xref: EHDAA:9868 xref: FMA:4723 xref: GAID:529 xref: galen:BrachiocephalicVein xref: MESH:D016121 xref: NCIT:C32816 xref: SCTID:181371003 xref: UMLS:C0006095 {source="ncithesaurus:Innominate_Vein"} xref: Wikipedia:Brachiocephalic_vein is_a: UBERON:0001638 ! vein relationship: BFO:0000050 RO:0002577 ! part of system relationship: BFO:0000050 UBERON:0007204 ! part of brachiocephalic vasculature relationship: RO:0002170 UBERON:0001585 ! connected to anterior vena cava property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/9/9e/Gray1174.png" xsd:anyURI [Term] id: UBERON:0003713 name: splenic vein namespace: uberon def: "A vein arising from the splenic trabecular vein in the hilum of the spleen that drains into the portal vein." [ncithesaurus:Splenic_Vein] xref: EMAPA:37226 {source="MA:th"} xref: FMA:14331 xref: GAID:541 xref: galen:SplenicVein xref: MA:0002164 xref: MESH:D013162 xref: NCIT:C33608 xref: SCTID:278029005 xref: UMLS:C0038001 {source="ncithesaurus:Splenic_Vein"} xref: Wikipedia:Splenic_vein is_a: UBERON:0001638 ! vein relationship: BFO:0000050 RO:0002577 ! part of system relationship: RO:0002170 UBERON:0001639 ! connected to hepatic portal vein property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/5/5b/Gray1189.png" xsd:anyURI property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/e/e4/Bilebladder.png" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI [Term] id: UBERON:0003714 name: neural tissue namespace: uberon def: "Portion of tissue in the nervous system which consists of neurons and glial cells, and may also contain parts of the vasculature." [FMA:9642] synonym: "nerve tissue" EXACT [FMA:9642] synonym: "nervous tissue" EXACT [FMA:9642] synonym: "portion of neural tissue" EXACT [FMA:9642] xref: AAO:0000325 xref: AEO:0000123 xref: EHDAA2:0003123 xref: FMA:9642 xref: GAID:609 xref: MESH:D009417 xref: NCIT:C13052 xref: SCTID:91728009 xref: UMLS:C0027757 {source="ncithesaurus:Nervous_Tissue"} is_a: UBERON:0000479 ! tissue intersection_of: UBERON:0000479 ! tissue intersection_of: BFO:0000051 CL:0000125 ! has part glial cell intersection_of: BFO:0000051 CL:0000540 ! has part neuron disjoint_from: UBERON:0004755 ! skeletal tissue relationship: BFO:0000050 UBERON:0001016 ! part of nervous system relationship: BFO:0000051 CL:0000125 ! has part glial cell relationship: BFO:0000051 CL:0000540 ! has part neuron [Term] id: UBERON:0003715 name: splanchnic nerve namespace: uberon def: "The major nerves supplying sympathetic innervation to the abdomen, including the greater, lesser, and lowest (or smallest) splanchnic nerves that are formed by preganglionic fibers from the spinal cord which pass through the paravertebral ganglia and then to the celiac ganglia and plexuses and the lumbar splanchnic nerves carry fibers which pass through the lumbar paravertebral ganglia to the mesenteric and hypogastric ganglia." [MP:0008318] xref: BAMS:spn xref: EMAPA:37959 {source="MA:th"} xref: FMA:5883 xref: GAID:800 xref: MESH:D013153 xref: SCTID:264198001 xref: Wikipedia:Splanchnic_nerves is_a: UBERON:0034729 ! sympathetic nerve intersection_of: UBERON:0001021 ! nerve intersection_of: RO:0002134 UBERON:0000916 ! innervates abdomen relationship: RO:0002134 UBERON:0000916 ! innervates abdomen relationship: RO:0002433 UBERON:0000013 ! contributes to morphology of sympathetic nervous system [Term] id: UBERON:0003726 name: thoracic nerve namespace: uberon def: "The twelve spinal nerves on each side of the thorax. They include eleven INTERCOSTAL NERVES and one subcostal nerve. Both sensory and motor, they supply the muscles and skin of the thoracic and abdominal walls." [MESH:A08.800.800.720.800] synonym: "thoracic spinal nerve" EXACT [FMA:5860] xref: FMA:5860 xref: GAID:857 xref: MESH:D013900 xref: neuronames:1725 xref: SCTID:360498003 xref: Wikipedia:Thoracic_nerves is_a: UBERON:0001780 ! spinal nerve intersection_of: UBERON:0001780 ! spinal nerve intersection_of: extends_fibers_into UBERON:0003038 ! thoracic spinal cord relationship: extends_fibers_into UBERON:0003038 ! thoracic spinal cord [Term] id: UBERON:0003727 name: intercostal nerve namespace: uberon def: "The intercostal nerves are the anterior divisions (rami anteriores; ventral divisions) of the thoracic spinal nerves from T1 to T11. Each nerve is connected with the adjoining ganglion of the sympathetic trunk by a gray and a white ramus communicans. The intercostal nerves are distributed chiefly to the thoracic pleura and abdominal peritoneum and differ from the anterior divisions of the other spinal nerves in that each pursues an independent course without plexus formation. The first two nerves supply fibers to the upper limb in addition to their thoracic branches; the next four are limited in their distribution to the parietes of the thorax; the lower five supply the parietes of the thorax and abdomen. The 7th intercostal nerve terminates at the xyphoid process, at the lower end of the sternum. The 10th intercostal nerve terminates at the umbilicus. The twelfth thoracic is distributed to the abdominal wall and groin. [WP,unvetted]." [Wikipedia:Intercostal_nerves] synonym: "anterior ramus of thoracic nerve" EXACT [FMA:6028] synonym: "anterior ramus of thoracic spinal nerve" EXACT [FMA:6028] synonym: "ramus anterior, nervus thoracicus" EXACT [FMA:6028] synonym: "thoracic anterior ramus" EXACT [FMA:6028] synonym: "ventral ramus of thoracic spinal nerve" EXACT [FMA:6028] xref: EMAPA:18227 xref: FMA:6028 xref: GAID:858 xref: MESH:D007367 xref: NCIT:C32825 xref: SCTID:279568001 xref: UMLS:C1285089 {source="ncithesaurus:Intercostal_Nerve"} xref: Wikipedia:Intercostal_nerves is_a: UBERON:0001780 ! spinal nerve property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/b/b1/Gray819.png" xsd:anyURI [Term] id: UBERON:0003728 name: mediastinum namespace: uberon def: "The central part of the thoracic cavity enclosed by the left and right pleurae." [UBERON:cjm, Wikipedia:Mediastinum] synonym: "mediastinal part of chest" EXACT [FMA:9826] xref: CALOHA:TS-2338 xref: EFO:0003057 xref: EMAPA:36001 xref: FMA:9826 xref: GAID:94 xref: MA:0003075 xref: MESH:D008482 xref: NCIT:C12748 xref: SCTID:181217005 xref: UMLS:C0025066 {source="ncithesaurus:Mediastinum"} xref: Wikipedia:Mediastinum is_a: UBERON:0002553 ! anatomical cavity relationship: BFO:0000050 UBERON:0002224 ! part of thoracic cavity relationship: RO:0002219 UBERON:0035431 {source="FMA"} ! surrounded by mediastinal pleura property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/a/ab/Mediastinum.png" xsd:anyURI [Term] id: UBERON:0003729 name: mouth mucosa namespace: uberon def: "A mucous membrane that lines the mouth." [http://orcid.org/0000-0002-6601-2165] synonym: "mouth mucosa" EXACT [FMA:59660] synonym: "mouth mucous membrane" EXACT [OBOL:accepted] synonym: "mouth organ mucosa" EXACT [OBOL:accepted] synonym: "mucosa of mouth" EXACT [OBOL:accepted] synonym: "mucous membrane of mouth" EXACT [FMA:59660] synonym: "oral mucous membrane" EXACT [] synonym: "oral part of viscerocranial mucosa" EXACT [FMA:59660] xref: BTO:0002860 xref: CALOHA:TS-0716 xref: EMAPA:26937 xref: FMA:59660 xref: GAID:951 xref: MA:0002794 xref: MESH:D009061 xref: NCIT:C77637 xref: UMLS:C0026639 {source="ncithesaurus:Oral_Mucosa"} xref: Wikipedia:Oral_mucosa is_a: UBERON:0000344 ! mucosa intersection_of: UBERON:0000344 ! mucosa intersection_of: BFO:0000050 UBERON:0000165 ! part of mouth relationship: RO:0002007 UBERON:0000165 ! bounding layer of mouth relationship: RO:0002150 UBERON:0000355 ! continuous with pharyngeal mucosa relationship: RO:0002150 UBERON:0001458 ! continuous with skin of lip relationship: RO:0002433 UBERON:0001007 ! contributes to morphology of digestive system property_value: IAO:0000232 "this is defined as any mucous membrane of the mouth - including palate, lips, uvula, etc. ncit split mouth/oral mucosa into lip and buccal. In future we may split into masticatory/keratinized (gingiva + hard palate) vs lining/non-keratinized (lips, cheeks, floor of mouth, soft palate). FMA distinguishes between mucosa of mouth and region of mouth (the latter including the buccal mucosa)" xsd:string [Term] id: UBERON:0003824 name: nerve of thoracic segment namespace: uberon def: "A nerve that is part of a thorax [Automatically generated definition]." [OBOL:automatic] synonym: "nerve of thorax" EXACT [OBOL:automatic] synonym: "thoracic segment nerve" EXACT [MA:0000562] synonym: "thorax nerve" EXACT [OBOL:automatic] xref: EMAPA:37265 {source="MA:th"} xref: MA:0000562 xref: MESH:D013900 xref: SCTID:359876006 is_a: UBERON:0003439 ! nerve of trunk region intersection_of: UBERON:0001021 ! nerve intersection_of: BFO:0000050 UBERON:0000915 ! part of thoracic segment of trunk relationship: BFO:0000050 UBERON:0000915 ! part of thoracic segment of trunk [Term] id: UBERON:0003825 name: nerve of abdominal segment namespace: uberon def: "A nerve that is part of an abdominal segment of trunk [Automatically generated definition]." [OBOL:automatic] synonym: "abdominal segment nerve" EXACT [MA:0000528] xref: EMAPA:37061 {source="MA:th"} xref: MA:0000528 is_a: UBERON:0003439 ! nerve of trunk region intersection_of: UBERON:0001021 ! nerve intersection_of: BFO:0000050 UBERON:0002417 ! part of abdominal segment of trunk relationship: BFO:0000050 UBERON:0002417 ! part of abdominal segment of trunk [Term] id: UBERON:0003827 name: thoracic segment bone namespace: uberon def: "A bone that is part of a thorax [Automatically generated definition]." [OBOL:automatic] synonym: "bone of thorax" EXACT [OBOL:automatic] synonym: "bone organ of thorax" EXACT [OBOL:automatic] synonym: "thorax bone" EXACT [OBOL:automatic] synonym: "thorax bone organ" EXACT [OBOL:automatic] xref: EMAPA:37247 {source="MA:th"} xref: MA:0000559 xref: SCTID:426649006 is_a: UBERON:0003463 ! trunk bone is_a: UBERON:0005181 ! thoracic segment organ intersection_of: UBERON:0001474 ! bone element intersection_of: BFO:0000050 UBERON:0000915 ! part of thoracic segment of trunk [Term] id: UBERON:0003828 name: abdominal segment bone namespace: uberon def: "A bone that is part of an abdominal segment of trunk [Automatically generated definition]." [OBOL:automatic] synonym: "abdominal segment of trunk bone" EXACT [OBOL:automatic] synonym: "abdominal segment of trunk bone organ" EXACT [OBOL:automatic] synonym: "bone of abdominal segment of trunk" EXACT [OBOL:automatic] synonym: "bone organ of abdominal segment of trunk" EXACT [OBOL:automatic] xref: EMAPA:37058 {source="MA:th"} xref: MA:0000525 is_a: UBERON:0003463 ! trunk bone is_a: UBERON:0005173 ! abdominal segment element intersection_of: UBERON:0001474 ! bone element intersection_of: BFO:0000050 UBERON:0002417 ! part of abdominal segment of trunk [Term] id: UBERON:0003829 name: urethra muscle tissue namespace: uberon def: "Any muscle tissue that is part of the urethra." [UBERON:cjm] xref: EMAPA:37787 {source="MA:th"} xref: MA:0002649 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005090 ! muscle structure intersection_of: UBERON:0005090 ! muscle structure intersection_of: BFO:0000050 UBERON:0000057 ! part of urethra relationship: BFO:0000050 UBERON:0000057 ! part of urethra [Term] id: UBERON:0003830 name: thoracic segment muscle namespace: uberon def: "Any muscle organ that is part of a thorax [Automatically generated definition]." [OBOL:automatic] synonym: "muscle organ of thorax" EXACT [OBOL:automatic] synonym: "thorax muscle organ" EXACT [OBOL:automatic] xref: MA:0000561 is_a: UBERON:0001774 ! skeletal muscle of trunk is_a: UBERON:0005181 ! thoracic segment organ intersection_of: UBERON:0014892 ! skeletal muscle organ, vertebrate intersection_of: BFO:0000050 UBERON:0000915 ! part of thoracic segment of trunk relationship: BFO:0000050 UBERON:0004464 {source="prolog"} ! part of musculature of thorax [Term] id: UBERON:0003831 name: respiratory system muscle namespace: uberon def: "Any muscle organ that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "apparatus respiratorius muscle organ" EXACT [OBOL:automatic] synonym: "muscle organ of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "muscle organ of respiratory system" EXACT [OBOL:automatic] synonym: "respiratory system muscle organ" EXACT [OBOL:automatic] xref: EMAPA:35733 xref: MA:0001828 is_a: UBERON:0001630 ! muscle organ intersection_of: UBERON:0001630 ! muscle organ intersection_of: BFO:0000050 UBERON:0001004 ! part of respiratory system relationship: BFO:0000050 UBERON:0001004 ! part of respiratory system [Term] id: UBERON:0003832 name: esophagus muscle namespace: uberon def: "Any muscle organ that is part of a esophagus [Automatically generated definition]." [OBOL:automatic] synonym: "esophageal muscle" EXACT [] synonym: "esophagus muscle organ" EXACT [OBOL:automatic] synonym: "gullet muscle organ" EXACT [OBOL:automatic] synonym: "muscle organ of esophagus" EXACT [OBOL:automatic] synonym: "muscle organ of gullet" EXACT [OBOL:automatic] synonym: "muscle organ of oesophagus" EXACT [OBOL:automatic] synonym: "oesophagus muscle organ" EXACT [OBOL:automatic] xref: EMAPA:26983 xref: MA:0002682 xref: SCTID:360961009 is_a: UBERON:0001630 ! muscle organ is_a: UBERON:0005181 ! thoracic segment organ is_a: UBERON:0013765 ! digestive system element intersection_of: UBERON:0001630 ! muscle organ intersection_of: BFO:0000050 UBERON:0001043 ! part of esophagus relationship: BFO:0000050 UBERON:0001096 {source="MA"} ! part of wall of esophagus [Term] id: UBERON:0003833 name: abdominal segment muscle namespace: uberon def: "A muscle organ that is part of an abdominal segment of trunk [Automatically generated definition]." [OBOL:automatic] synonym: "abdominal segment of trunk muscle organ" EXACT [OBOL:automatic] synonym: "muscle organ of abdominal segment of trunk" EXACT [OBOL:automatic] xref: EMAPA:37060 {source="MA:th"} xref: MA:0000527 is_a: UBERON:0001774 ! skeletal muscle of trunk is_a: UBERON:0005173 ! abdominal segment element intersection_of: UBERON:0014892 ! skeletal muscle organ, vertebrate intersection_of: BFO:0000050 UBERON:0002417 ! part of abdominal segment of trunk [Term] id: UBERON:0003834 name: thoracic segment blood vessel namespace: uberon def: "A blood vessel that is part of a thorax [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of thorax" EXACT [OBOL:automatic] synonym: "thorax blood vessel" EXACT [OBOL:automatic] xref: EMAPA:37238 {source="MA:th"} xref: MA:0000558 is_a: UBERON:0003513 ! trunk blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: BFO:0000050 UBERON:0000915 ! part of thoracic segment of trunk relationship: BFO:0000050 UBERON:0000915 ! part of thoracic segment of trunk [Term] id: UBERON:0003835 name: abdominal segment blood vessel namespace: uberon def: "A blood vessel that is part of an abdominal segment of trunk [Automatically generated definition]." [OBOL:automatic] synonym: "abdominal segment of trunk blood vessel" EXACT [OBOL:automatic] synonym: "blood vessel of abdominal segment of trunk" EXACT [OBOL:automatic] xref: EMAPA:37057 {source="MA:th"} xref: MA:0000524 is_a: UBERON:0003513 ! trunk blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: BFO:0000050 UBERON:0002417 ! part of abdominal segment of trunk relationship: BFO:0000050 UBERON:0002417 ! part of abdominal segment of trunk [Term] id: UBERON:0003836 name: abdominal segment skin namespace: uberon def: "A skin of body that is part of an abdominal segment of trunk [Automatically generated definition]." [OBOL:automatic] synonym: "abdominal segment of trunk skin" EXACT [OBOL:automatic] synonym: "skin of abdominal segment of trunk" EXACT [OBOL:automatic] xref: EMAPA:37063 {source="MA:th"} xref: FMA:264898 xref: MA:0000530 is_a: UBERON:0001085 ! skin of trunk intersection_of: UBERON:0000014 ! zone of skin intersection_of: BFO:0000050 UBERON:0002417 ! part of abdominal segment of trunk relationship: BFO:0000050 UBERON:0002417 ! part of abdominal segment of trunk [Term] id: UBERON:0003837 name: thoracic segment connective tissue namespace: uberon def: "A portion of connective tissue that is part of a thorax [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of thorax" EXACT [OBOL:automatic] synonym: "portion of connective tissue of thorax" EXACT [OBOL:automatic] synonym: "textus connectivus of thorax" EXACT [OBOL:automatic] synonym: "thorax connective tissue" EXACT [OBOL:automatic] synonym: "thorax portion of connective tissue" EXACT [OBOL:automatic] synonym: "thorax textus connectivus" EXACT [OBOL:automatic] xref: EMAPA:37253 {source="MA:th"} xref: MA:0000560 is_a: UBERON:0003586 ! trunk connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: BFO:0000050 UBERON:0000915 ! part of thoracic segment of trunk relationship: BFO:0000050 UBERON:0000915 ! part of thoracic segment of trunk [Term] id: UBERON:0003838 name: abdominal segment connective tissue namespace: uberon def: "A portion of connective tissue that is part of an abdominal segment of trunk [Automatically generated definition]." [OBOL:automatic] synonym: "abdominal segment of trunk connective tissue" EXACT [OBOL:automatic] synonym: "abdominal segment of trunk portion of connective tissue" EXACT [OBOL:automatic] synonym: "abdominal segment of trunk textus connectivus" EXACT [OBOL:automatic] synonym: "connective tissue of abdominal segment of trunk" EXACT [OBOL:automatic] synonym: "portion of connective tissue of abdominal segment of trunk" EXACT [OBOL:automatic] synonym: "textus connectivus of abdominal segment of trunk" EXACT [OBOL:automatic] xref: EMAPA:37059 {source="MA:th"} xref: MA:0000526 is_a: UBERON:0003586 ! trunk connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: BFO:0000050 UBERON:0002417 ! part of abdominal segment of trunk relationship: BFO:0000050 UBERON:0002417 ! part of abdominal segment of trunk [Term] id: UBERON:0003842 name: neural tube lumen namespace: uberon def: "An anatomical space that surrounded_by a neural tube." [OBOL:automatic] synonym: "cavity of neural tube" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "lumen of neural tube" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "neural tube neural lumen" EXACT [EHDAA2:0001269] xref: AAO:0011073 xref: EHDAA2:0001269 xref: EHDAA:2889 xref: EHDAA:914 xref: EMAPA:16167 xref: VHOG:0001119 xref: XAO:0000252 is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: RO:0002572 UBERON:0001049 ! luminal space of neural tube relationship: RO:0002572 UBERON:0001049 ! luminal space of neural tube [Term] id: UBERON:0003848 name: gonadal vein namespace: uberon def: "In medicine, gonadal vein refers to the blood vessel that carrying blood away from the gonad (testis, ovary) toward the heart. Females : ovarian vein Males : testicular vein [WP,unvetted]." [Wikipedia:Gonadal_vein] synonym: "gonad vein" EXACT [OBOL:automatic] synonym: "gonada vein" EXACT [OBOL:automatic] synonym: "vein of gonad" EXACT [OBOL:automatic] synonym: "vein of gonada" EXACT [OBOL:automatic] xref: EHDAA2:0000719 xref: EHDAA:8703 xref: SCTID:278192008 xref: VHOG:0001340 xref: Wikipedia:Gonadal_vein is_a: UBERON:0001638 ! vein intersection_of: UBERON:0001638 ! vein intersection_of: RO:0002371 UBERON:0000991 ! attached to gonad relationship: BFO:0000050 RO:0002577 ! part of system relationship: RO:0002371 UBERON:0000991 ! attached to gonad property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/d/da/Gray1120.png" xsd:anyURI [Term] id: UBERON:0003849 name: mesencephalic neural crest namespace: uberon def: "A neural crest that has_potential_to_developmentally_contribute_to a midbrain." [OBOL:automatic] synonym: "mesencephalic neural crest" EXACT [ZFA:0000935] synonym: "neural crest midbrain" EXACT [ZFA:0000935] xref: EFO:0003591 xref: EHDAA2:0001101 xref: EHDAA:360 xref: TAO:0000935 xref: VHOG:0000796 xref: ZFA:0000935 is_a: UBERON:0002342 ! neural crest is_a: UBERON:0003099 {source="ZFA"} ! cranial neural crest intersection_of: UBERON:0002342 ! neural crest intersection_of: RO:0002385 UBERON:0001891 ! has potential to developmentally contribute to midbrain relationship: RO:0002385 UBERON:0001891 ! has potential to developmentally contribute to midbrain [Term] id: UBERON:0003852 name: rhombencephalon neural crest namespace: uberon def: "A neural crest that has_potential_to_developmentally_contribute_to a hindbrain." [OBOL:automatic] synonym: "neural crest hindbrain" EXACT [ZFA:0007063] synonym: "rhombencephalic neural crest" EXACT [ZFA:0007063] xref: EHDAA2:0001628 xref: EHDAA:362 xref: EMAPA:35747 xref: TAO:0007063 xref: VHOG:0001210 xref: ZFA:0007063 is_a: UBERON:0002342 ! neural crest is_a: UBERON:0003099 {source="ZFA"} ! cranial neural crest intersection_of: UBERON:0002342 ! neural crest intersection_of: RO:0002385 UBERON:0002028 ! has potential to developmentally contribute to hindbrain relationship: RO:0002385 UBERON:0002028 ! has potential to developmentally contribute to hindbrain [Term] id: UBERON:0003853 name: spinal cord neural crest namespace: uberon def: "A neural crest that has_potential_to_developmentally_contribute_to a spinal cord." [OBOL:automatic] synonym: "neural crest spinal cord" EXACT [VHOG:0001006] xref: EHDAA:696 xref: EMAPA:16163 xref: EMAPA:16881 xref: VHOG:0001006 is_a: UBERON:0002342 ! neural crest intersection_of: UBERON:0002342 ! neural crest intersection_of: RO:0002385 UBERON:0002240 ! has potential to developmentally contribute to spinal cord relationship: RO:0002385 UBERON:0002240 ! has potential to developmentally contribute to spinal cord [Term] id: UBERON:0003854 name: spinal cord neural plate namespace: uberon def: "A neural plate that develops_from a future spinal cord." [OBOL:automatic] synonym: "neural plate of spinal cord" EXACT [OBOL:automatic] xref: FMA:312957 xref: TAO:0007021 xref: VHOG:0000439 xref: ZFA:0007021 is_a: UBERON:0003075 ! neural plate intersection_of: UBERON:0003075 ! neural plate intersection_of: RO:0002202 UBERON:0006241 ! develops from future spinal cord relationship: RO:0002202 UBERON:0006241 {source="ZFA"} ! develops from future spinal cord [Term] id: UBERON:0003855 name: gonad mesenchyme namespace: uberon def: "Mesenchyme that is part of a developing gonad [Automatically generated definition]." [OBOL:automatic] synonym: "gonada mesenchyme" EXACT [OBOL:automatic] synonym: "mesenchyme of gonad" EXACT [OBOL:automatic] synonym: "mesenchyme of gonada" EXACT [OBOL:automatic] xref: EHDAA:5012 xref: EMAPA:16858 xref: EMAPA:17385 xref: VHOG:0001090 is_a: UBERON:0003104 ! mesenchyme is_a: UBERON:0005156 ! reproductive structure intersection_of: UBERON:0003104 ! mesenchyme intersection_of: BFO:0000050 UBERON:0000991 ! part of gonad relationship: BFO:0000050 UBERON:0000991 ! part of gonad [Term] id: UBERON:0003869 name: presumptive ganglion namespace: uberon def: "A presumptive structure that has the potential to develop into a ganglion." [OBOL:automatic] is_a: UBERON:0006598 ! presumptive structure intersection_of: UBERON:0006598 ! presumptive structure intersection_of: RO:0002387 UBERON:0000045 ! has potential to develop into ganglion relationship: RO:0002387 UBERON:0000045 ! has potential to develop into ganglion [Term] id: UBERON:0003885 name: mesometrium namespace: uberon def: "A mesentery that is part of a uterus [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:35562 xref: FMA:19816 xref: MA:0002931 xref: SCTID:250172001 xref: Wikipedia:Mesometrium is_a: UBERON:0001297 ! serosa of uterus is_a: UBERON:0002095 ! mesentery intersection_of: UBERON:0002095 ! mesentery intersection_of: BFO:0000050 UBERON:0000995 ! part of uterus relationship: BFO:0000050 UBERON:0012332 ! part of broad ligament of uterus [Term] id: UBERON:0003886 name: future coelemic cavity lumen namespace: uberon def: "An anatomical cavity that has the potential to develop into a coelemic cavity lumen." [OBOL:automatic] synonym: "future coelomic cavity lumen" EXACT [] is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: RO:0002387 UBERON:0002323 ! has potential to develop into coelemic cavity lumen relationship: BFO:0000050 UBERON:0000926 ! part of mesoderm relationship: RO:0002387 UBERON:0002323 ! has potential to develop into coelemic cavity lumen relationship: RO:0002488 UBERON:0000109 ! existence starts during gastrula stage relationship: RO:0002492 UBERON:0000111 ! existence ends during organogenesis stage [Term] id: UBERON:0003887 name: intraembryonic coelom namespace: uberon def: "The part of the coelom in the embryo between the somatopleuric and splanchnopleuric mesoderm; the principal body cavities of the trunk (thoracic, abdominal, and pelvic) arise from this embryonic part of the coelom." [MGI:anna, MP:0012187] synonym: "somatic coelom" EXACT [Wikipedia:Intraembryonic_coelom] xref: EHDAA:251 xref: EMAPA:16088 xref: NCIT:C34195 xref: UMLS:C1512940 {source="ncithesaurus:Intraembryonic_Coelom"} xref: VHOG:0000316 xref: Wikipedia:Intraembryonic_coelom is_a: UBERON:0002050 ! embryonic structure relationship: BFO:0000050 UBERON:0011997 ! part of coelom relationship: RO:0002202 UBERON:0003081 {source="Wikipedia"} ! develops from lateral plate mesoderm [Term] id: UBERON:0003889 name: fallopian tube namespace: uberon def: "Initial section of the oviduct through which the ova pass from the ovary to the uterus." [http://orcid.org/0000-0002-6601-2165, MGI:smb, MP:0003574] synonym: "mammalian oviduct" EXACT [https://sourceforge.net/p/geneontology/ontology-requests/8397/] synonym: "uterine tube (sensu Mammalia)" EXACT [] xref: CALOHA:TS-0732 xref: EHDAA2:0000504 xref: EMAPA:18984 xref: EMAPA:35660 xref: EV:0100112 xref: FMA:18245 xref: GAID:365 xref: galen:FallopianTube xref: MA:0000385 xref: MESH:D005187 xref: NCIT:C12403 xref: SCTID:181463001 xref: UMLS:C0015560 {source="ncithesaurus:Fallopian_Tube"} xref: Wikipedia:Fallopian_tube is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0013515 ! subdivision of oviduct is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0013515 ! subdivision of oviduct intersection_of: BFO:0000050 UBERON:0000993 ! part of oviduct intersection_of: RO:0002202 UBERON:0003890 ! develops from Mullerian duct relationship: BFO:0000050 UBERON:0002355 ! part of pelvic region of trunk relationship: BSPO:0000126 UBERON:0003975 {source="FMA-abduced-lr"} ! in lateral side of internal female genitalia relationship: RO:0002160 NCBITaxon:40674 ! only in taxon Mammalia relationship: RO:0002176 UBERON:0000995 ! connects uterus relationship: RO:0002176 UBERON:0003984 ! connects uterine tube infundibulum relationship: RO:0002202 UBERON:0003890 ! develops from Mullerian duct property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/6/68/Scheme_female_reproductive_system-en.svg" xsd:anyURI [Term] id: UBERON:0003890 name: Mullerian duct namespace: uberon def: "Paired ducts of the embryo that run down the lateral sides of the urogenital ridge and terminate at the mullerian eminence in the primitive urogenital sinus. In the female, they will develop to form the fallopian tubes, uterus, and the upper portion of the vagina; in the male, they are lost. These ducts are made of tissue of mesodermal origin[WP]. develops either by lengthwise splitting of the archinephric duct (in chondrichthyans and some amphibians) or by a elongated invagination of the coelomic epithelium (other vertebrates) In males, the oviducts regress. The cranial end of the oviduct maintains an opening into the coelom (which primitively may have been the anteriormost coelomic funnels connecting the nephrocoel with the coelom). This opening is the ostium tubae[USM]." [GO:0061205, http://www.usm.maine.edu/bio/courses/bio205/bio205_26_sex.html, Wikipedia:Paramesonephric_duct] synonym: "ductus paramesonephricus" EXACT [] synonym: "Muellerian duct" EXACT [] synonym: "Müllerian duct" EXACT [] synonym: "paramesonephric duct" EXACT [EMAPA:27665] xref: AAO:0010141 xref: EHDAA2:0004048 xref: EMAPA:27665 xref: GAID:1309 xref: MESH:D009095 xref: NCIT:C13260 xref: RETIRED_EHDAA2:0001399 xref: SCTID:308802006 xref: UMLS:C0026732 {source="ncithesaurus:Mullerian_Duct"} xref: VHOG:0001199 xref: Wikipedia:Paramesonephric_duct xref: XAO:0000330 is_a: UBERON:0000025 ! tube is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0015212 ! lateral structure relationship: BSPO:0000126 UBERON:0000922 ! in lateral side of embryo relationship: RO:0002202 UBERON:0003064 {source="Wikipedia"} ! develops from intermediate mesoderm property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/6/6d/Gray1109.png" xsd:anyURI [Term] id: UBERON:0003891 name: stroma namespace: uberon def: "Connective, non-functional supportive framework of a biological cell, tissue, or organ. Contrast with parenchyma." [http://orcid.org/0000-0002-6601-2165] xref: FMA:81494 xref: NCIT:C67387 xref: UMLS:C0927195 {source="ncithesaurus:Stroma_Connective_Tissue"} is_a: UBERON:0000064 ! organ part relationship: RO:0002160 NCBITaxon:6072 ! only in taxon Eumetazoa relationship: RO:0002473 UBERON:0002384 ! composed primarily of connective tissue [Term] id: UBERON:0003894 name: liver primordium namespace: uberon def: "A small endodermal thickening in the foregut adjacent to the transverse septum. Invaginates forming the hepatic diverticulum." [ISBN:3211492755] synonym: "embryological hepatic plate" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "primordium of the liver" EXACT [ncithesaurus:Primordium_of_the_Liver] xref: AAO:0011058 xref: BTO:0003391 xref: EFO:0002577 xref: EFO:0003428 xref: EHDAA2:0000744 xref: EHDAA:973 xref: EMAPA:16847 xref: NCIT:C34277 xref: TAO:0000124 xref: UMLS:C0734013 {source="ncithesaurus:Hepatic_Cord"} xref: UMLS:C1514451 {source="ncithesaurus:Primordium_of_the_Liver"} xref: XAO:0003266 xref: ZFA:0000124 is_a: UBERON:0000485 {source="EHDAA2"} ! simple columnar epithelium is_a: UBERON:0001048 {source="XAO"} ! primordium is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0006598 ! presumptive structure is_a: UBERON:0009497 ! epithelium of foregut-midgut junction intersection_of: UBERON:0001048 ! primordium intersection_of: RO:0002387 UBERON:0002107 ! has potential to develop into liver relationship: BFO:0000050 UBERON:0009550 {source="EHDAA2"} ! part of endoderm of foregut-midgut junction relationship: RO:0002202 UBERON:0001041 ! develops from foregut relationship: RO:0002387 UBERON:0002107 ! has potential to develop into liver [Term] id: UBERON:0003897 name: axial muscle namespace: uberon def: "One of the skeletal muscles of the head and neck, spine, and ribs." [HP:0003327] xref: EHDAA:5982 xref: EMAPA:18167 xref: MA:0003153 xref: RETIRED_EHDAA2:0000160 xref: TAO:0001954 is_a: UBERON:0014892 ! skeletal muscle organ, vertebrate intersection_of: UBERON:0014892 ! skeletal muscle organ, vertebrate intersection_of: BFO:0000050 UBERON:0013701 ! part of main body axis intersection_of: RO:0002177 UBERON:0005944 ! attached to part of axial skeleton plus cranial skeleton relationship: BFO:0000050 UBERON:0013700 ! part of axial musculature relationship: RO:0002177 UBERON:0005944 ! attached to part of axial skeleton plus cranial skeleton [Term] id: UBERON:0003898 name: skeletal muscle tissue of trunk namespace: uberon def: "A portion of skeletal muscle tissue in the trunk." [http://orcid.org/0000-0002-6601-2165] synonym: "skeletal muscle of torso" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue of torso" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue of trunk" EXACT [OBOL:automatic] synonym: "torso skeletal muscle" EXACT [OBOL:automatic] synonym: "torso skeletal muscle tissue" EXACT [OBOL:automatic] synonym: "trunk skeletal muscle" EXACT [OBOL:automatic] synonym: "trunk skeletal muscle tissue" EXACT [OBOL:automatic] xref: SCTID:244848007 is_a: UBERON:0001134 ! skeletal muscle tissue intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: BFO:0000050 UBERON:0002100 ! part of trunk relationship: BFO:0000050 UBERON:0004479 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! part of musculature of trunk relationship: BFO:0000050 UBERON:0013700 ! part of axial musculature [Term] id: UBERON:0003902 name: retinal neural layer namespace: uberon def: "The part of the retina that contains neurons and photoreceptor cells[GO]." [GO:0003407] synonym: "neural layer of retina" EXACT [FMA:58628] synonym: "neural retina" EXACT [XAO:0003216, ZFA:0000046] synonym: "neuroretina" EXACT [ZFA:0000046] synonym: "stratum nervosum (retina)" EXACT [FMA:58628] xref: AAO:0011095 xref: BTO:0000929 xref: CALOHA:TS-0685 xref: EHDAA2:0001253 xref: EHDAA:4763 xref: EMAPA:17171 xref: EMAPA:18590 xref: FMA:58628 xref: MA:0000277 xref: NCIT:C33166 xref: TAO:0000046 xref: UMLS:C1518263 {source="ncithesaurus:Neural_Retina"} xref: VHOG:0000535 xref: XAO:0003216 xref: ZFA:0000046 is_a: UBERON:0001781 ! layer of retina intersection_of: UBERON:0001781 ! layer of retina intersection_of: RO:0002495 UBERON:0005425 ! immediate transformation of presumptive neural retina relationship: BFO:0000051 CL:0000210 ! has part photoreceptor cell relationship: RO:0002256 UBERON:0005426 ! developmentally induced by lens vesicle relationship: RO:0002495 UBERON:0005425 {source="Bgee:AN"} ! immediate transformation of presumptive neural retina [Term] id: UBERON:0003909 name: sinusoid namespace: uberon def: "Small blood vessel similar to a capillary but with a fenestrated endothelium. Sinusoids are found in the liver, lymphoid tissue, endocrine organs, and hematopoietic organs such as the bone marrow and the spleen. Sinusoids found within terminal villi of the placenta are not comparable to these; they possess a continuous endothelium and complete basal lamina[WP]." [Wikipedia:Sinusoid_(blood_vessel)] synonym: "sinusoidal blood vessel" EXACT [] synonym: "sinusoidal blood vessel endothelium" EXACT [ZFA:0005261] xref: FMA:63131 xref: SCTID:340163004 xref: TAO:0005261 xref: Wikipedia:Sinusoid_(blood_vessel) xref: ZFA:0005261 is_a: UBERON:2005260 {source="Wikipedia", source="ZFA"} ! fenestrated capillary [Term] id: UBERON:0003914 name: epithelial tube namespace: uberon def: "Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system." [GO:0060562, PMID:12526790] synonym: "epithelial or endothelial tube" EXACT [] xref: AEO:0000114 xref: EHDAA2:0003114 is_a: UBERON:0000025 ! tube is_a: UBERON:0000483 ! epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: RO:0000086 PATO:0002299 ! has quality tubular property_value: IAO:0000232 "contrast with a multi-tissue tube, which has as parts both epithelium, connective tissue, possibly muscle layers" xsd:string [Term] id: UBERON:0003915 name: endothelial tube namespace: uberon def: "Any endothelium that has the quality of being cylindrical [Automatically generated definition]." [OBOL:automatic] is_a: UBERON:0001986 ! endothelium is_a: UBERON:0003914 ! epithelial tube intersection_of: UBERON:0001986 ! endothelium intersection_of: RO:0000086 PATO:0002299 ! has quality tubular [Term] id: UBERON:0003918 name: kidney mesenchyme namespace: uberon def: "Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney[GO]." [GO:0072074] synonym: "mesenchyme of kidney" EXACT [] is_a: UBERON:0003104 ! mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: RO:0002387 UBERON:0002113 ! has potential to develop into kidney relationship: RO:0002387 UBERON:0002113 ! has potential to develop into kidney [Term] id: UBERON:0003920 name: venous blood vessel namespace: uberon def: "A blood vessel that carries blood from the capillaries toward the heart." [http://www.thefreedictionary.com/venous+blood+vessel] synonym: "segment of venous tree organ" EXACT [FMA:86188] synonym: "venous tree organ segment" EXACT [FMA:86188] xref: EMAPA:35932 xref: FMA:86188 xref: MA:0000066 is_a: UBERON:0001981 ! blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: BFO:0000050 UBERON:0004582 ! part of venous system relationship: BFO:0000050 UBERON:0004582 ! part of venous system [Term] id: UBERON:0003921 name: pancreas primordium namespace: uberon def: "Embryonic structure that develops into pancreatic bud." [Wikipedia:Pancreas#Embryological_development] synonym: "pancreatic primordium" EXACT [] xref: EFO:0002579 xref: EFO:0003434 xref: EHDAA2:0001382 xref: EHDAA:2163 xref: EMAPA:17066 xref: FMA:79792 xref: TAO:0000254 xref: XAO:0001101 xref: ZFA:0000254 is_a: UBERON:0001048 ! primordium is_a: UBERON:0006598 ! presumptive structure intersection_of: UBERON:0001048 ! primordium intersection_of: RO:0002387 UBERON:0001264 ! has potential to develop into pancreas relationship: BFO:0000050 UBERON:0007026 ! part of presumptive gut relationship: RO:0002202 UBERON:0000925 {source="Wikipedia"} ! develops from endoderm relationship: RO:0002387 UBERON:0001264 ! has potential to develop into pancreas property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/d/db/Gray982.png" xsd:anyURI [Term] id: UBERON:0003922 name: pancreatic epithelial bud namespace: uberon def: "The embryonic pancreas develops from two separate anlagen in the foregut epithelium, one dorsal and two ventral pancreatic buds[PMID]." [PMID:16417468, Wikipedia:Pancreatic_bud] synonym: "pancreatic bud" EXACT [ZFA:0001390] xref: EFO:0003470 xref: EMAPA:35645 xref: NCIT:C34242 xref: SCTID:360398004 xref: TAO:0001390 xref: UMLS:C1283285 {source="ncithesaurus:Pancreatic_Bud"} xref: Wikipedia:Pancreatic_bud xref: ZFA:0001390 is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0005911 ! endo-epithelium is_a: UBERON:0007499 {source="EHDAA2"} ! epithelial sac relationship: BFO:0000050 UBERON:0003921 {source="EHDAA2"} ! part of pancreas primordium relationship: RO:0002202 UBERON:0001041 {source="Wikipedia:Pancreas#Embryological_development"} ! develops from foregut relationship: RO:0002202 UBERON:0001555 ! develops from digestive tract relationship: RO:0002202 UBERON:0002114 ! develops from duodenum relationship: RO:0002202 UBERON:0009497 {source="EHDAA2-inferred"} ! develops from epithelium of foregut-midgut junction property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/4/49/Suckale08FBS_fig1_pancreas_development.jpeg" xsd:anyURI property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/d/db/Gray982.png" xsd:anyURI [Term] id: UBERON:0003923 name: dorsal pancreatic bud namespace: uberon def: "Pancreatic bud that gives rise to the accessory pancreatic duct." [Wikipedia:Pancreatic_bud] synonym: "pancreas dorsal primordium duct bud" EXACT [EHDAA2:0001385] synonym: "pancreas primordium dorsal bud" EXACT [] synonym: "primary pancreatic bud" EXACT [XAO:0000467] xref: AAO:0011031 xref: EFO:0003465 xref: EHDAA2:0001385 xref: EMAPA:17067 xref: SCTID:361435005 xref: TAO:0001370 xref: VHOG:0001428 xref: Wikipedia:Pancreatic_bud xref: XAO:0000467 xref: ZFA:0001370 is_a: UBERON:0003922 ! pancreatic epithelial bud relationship: BFO:0000050 UBERON:0010375 {source="EHDAA2"} ! part of pancreas dorsal primordium relationship: RO:0002202 UBERON:0001045 {source="XAO"} ! develops from midgut relationship: RO:0002256 UBERON:0002328 {gci_filler="NCBITaxon:10088", gci_relation="BFO:0000050", source="PMID:16417468"} ! developmentally induced by notochord relationship: RO:0002256 UBERON:0005805 {gci_filler="NCBITaxon:10088", gci_relation="BFO:0000050", source="PMID:16417468"} ! developmentally induced by dorsal aorta property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/d/db/Gray982.png" xsd:anyURI [Term] id: UBERON:0003924 name: ventral pancreatic bud namespace: uberon def: "Pancreatic bud that gives rise to the major pancreatic duct." [Wikipedia:Pancreatic_bud] synonym: "pancreas primordium ventral bud" EXACT [] synonym: "pancreas ventral primordium duct bud" EXACT [EHDAA2:0001389] xref: AAO:0011111 xref: EFO:0003464 xref: EHDAA2:0001389 xref: EMAPA:17256 xref: SCTID:361437002 xref: TAO:0001369 xref: VHOG:0001429 xref: Wikipedia:Pancreatic_bud xref: XAO:0001103 xref: ZFA:0001369 is_a: UBERON:0003922 ! pancreatic epithelial bud relationship: BFO:0000050 UBERON:0010376 {source="EHDAA2"} ! part of pancreas ventral primordium relationship: RO:0002202 UBERON:0008835 {source="PMID:16417468", source="WP"} ! develops from hepatic diverticulum property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/d/db/Gray982.png" xsd:anyURI [Term] id: UBERON:0003928 name: digestive system duct namespace: uberon def: "A duct that is part of a digestive system [Automatically generated definition]." [OBOL:automatic] synonym: "duct of digestive system" EXACT [OBOL:automatic] synonym: "duct of gastrointestinal system" EXACT [OBOL:automatic] synonym: "gastrointestinal system duct" EXACT [OBOL:automatic] xref: TAO:0005162 xref: ZFA:0005162 is_a: UBERON:0000058 ! duct intersection_of: UBERON:0000058 ! duct intersection_of: BFO:0000050 UBERON:0001007 ! part of digestive system relationship: BFO:0000050 UBERON:0001007 ! part of digestive system [Term] id: UBERON:0003929 name: digestive tract epithelium namespace: uberon def: "An epithelium that lines the lumen of the digestive tract." [http://orcid.org/0000-0002-6601-2165] synonym: "digestive tract epithelial tissue" EXACT [OBOL:automatic] synonym: "epithelial tissue of digestive tract" EXACT [OBOL:automatic] synonym: "epithelial tissue of gut" EXACT [OBOL:automatic] synonym: "epithelium of digestive tract" EXACT [OBOL:automatic] synonym: "epithelium of gut" EXACT [OBOL:automatic] synonym: "gut epithelial tissue" EXACT [OBOL:automatic] synonym: "gut epithelium" EXACT [EHDAA2:0004567, MA:0003201, ZFA:0005123] xref: BTO:0000956 xref: EHDAA2:0004567 xref: EMAPA:32928 xref: MA:0003201 xref: NCIT:C12963 xref: TAO:0005123 xref: UMLS:C0836205 {source="ncithesaurus:Gut_Epithelium"} xref: XAO:0003200 xref: ZFA:0005123 is_a: UBERON:0000483 ! epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: BFO:0000050 UBERON:0001555 ! part of digestive tract relationship: BFO:0000050 UBERON:0001555 ! part of digestive tract [Term] id: UBERON:0003932 name: cartilage element of chondrocranium namespace: uberon def: "A cartilage element of chondrocranium. Example: neurocranial trabecula." [https://orcid.org/0000-0002-6601-2165] synonym: "cartilage of chondrocranium" EXACT [OBOL:accepted] synonym: "cartilaginous element of chondrocranium" EXACT [OBOL:accepted] synonym: "chondrocranium cartilage" EXACT [ZFA:0001461] synonym: "neurocranium cartilage" EXACT [ZFA:0001461] xref: EFO:0003690 xref: TAO:0001461 xref: ZFA:0001461 is_a: UBERON:0003933 ! cranial cartilage intersection_of: UBERON:0007844 ! cartilage element intersection_of: BFO:0000050 UBERON:0002241 ! part of chondrocranium relationship: BFO:0000050 UBERON:0002241 ! part of chondrocranium [Term] id: UBERON:0003933 name: cranial cartilage namespace: uberon def: "A cartilage element that is part of the cranial skeleton." [https://orcid.org/0000-0002-6601-2165, ZFA:0001458] synonym: "cartilage of cranium" EXACT [OBOL:automatic] synonym: "cranium cartilage" EXACT [OBOL:automatic] xref: TAO:0001458 xref: ZFA:0001458 is_a: UBERON:0007844 ! cartilage element intersection_of: UBERON:0007844 ! cartilage element intersection_of: BFO:0000050 UBERON:0010323 ! part of cranial skeletal system relationship: BFO:0000050 UBERON:0010323 ! part of cranial skeletal system [Term] id: UBERON:0003937 name: reproductive gland namespace: uberon def: "Any of the organized aggregations of cells that function as secretory or excretory organs and are associated with reproduction." [MP:0000653] synonym: "genitalia gland" EXACT [OBOL:automatic] synonym: "gland of genitalia" EXACT [MP:0000653] synonym: "gland of reproductive system" EXACT [OBOL:automatic] synonym: "reproductive gland" EXACT [MA:0001751] synonym: "reproductive system gland" EXACT [OBOL:automatic] synonym: "sex gland" EXACT [MP:0000653] xref: MA:0001751 is_a: UBERON:0002530 ! gland is_a: UBERON:0005156 ! reproductive structure intersection_of: UBERON:0002530 ! gland intersection_of: BFO:0000050 UBERON:0000990 ! part of reproductive system [Term] id: UBERON:0003942 name: somatosensory system namespace: uberon def: "The sensory system for the sense of touch and pain." [NLXANAT:090818] synonym: "somatic sensory system" EXACT [] synonym: "system for detection of somatic senses" EXACT [] xref: EMAPA:37954 {source="MA:th"} xref: neuronames:2887 xref: NLXANAT:090818 xref: Wikipedia:Somatosensory_system is_a: UBERON:0001032 ! sensory system relationship: RO:0002216 GO:0019233 ! capable of part of sensory perception of pain relationship: RO:0002216 GO:0050975 ! capable of part of sensory perception of touch [Term] id: UBERON:0003946 name: placenta labyrinth namespace: uberon def: "The placental layers where embryonic blood vessels are surrounded by trophoblast cells and maternal blood." [MP:0001716] synonym: "labyrinthine layer" EXACT [GO:0060713] synonym: "labyrinthine layer of placenta" EXACT [GO:0060713] synonym: "placental labyrinth" EXACT [] is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005156 ! reproductive structure relationship: BFO:0000050 UBERON:0001987 ! part of placenta relationship: RO:0002433 UBERON:0001987 ! contributes to morphology of placenta [Term] id: UBERON:0003952 name: anterior stroma of cornea namespace: uberon def: "The anterior segment of the lamellated connective tissue layer of the cornea." [MP:0003093] synonym: "cornea anterior stroma" EXACT [MP:0003093] xref: EMAPA:37414 {source="MA:th"} is_a: UBERON:0003566 ! head connective tissue is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: UBERON:0002384 ! connective tissue intersection_of: BSPO:0000123 UBERON:0001777 ! in anterior side of substantia propria of cornea disjoint_from: UBERON:0003953 {source="lexical"} ! posterior stroma of cornea relationship: BSPO:0000123 UBERON:0001777 ! in anterior side of substantia propria of cornea relationship: RO:0002433 UBERON:0001777 ! contributes to morphology of substantia propria of cornea [Term] id: UBERON:0003953 name: posterior stroma of cornea namespace: uberon def: "The posterior segment of the lamellated connective tissue layer of the cornea." [MP:0003094] synonym: "cornea posterior stroma" EXACT [MP:0003094] xref: EMAPA:37415 {source="MA:th"} is_a: UBERON:0003566 ! head connective tissue is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: UBERON:0002384 ! connective tissue intersection_of: BSPO:0000122 UBERON:0001777 ! in posterior side of substantia propria of cornea relationship: BSPO:0000122 UBERON:0001777 ! in posterior side of substantia propria of cornea relationship: RO:0002433 UBERON:0001777 ! contributes to morphology of substantia propria of cornea [Term] id: UBERON:0003959 name: rete testis namespace: uberon def: "An anastomosing network of delicate tubules located in the hilum of the testicle (mediastinum testis) that carries sperm from the seminiferous tubules to the vasa efferentia[WP]." [MP:0006416, Wikipedia:Rete_testis] synonym: "Haller's rete" EXACT [FMA:19834] xref: EMAPA:18332 xref: FMA:19834 xref: GAID:399 xref: MA:0003013 xref: MESH:D012152 xref: NCIT:C33467 xref: SCTID:279617009 xref: UMLS:C0035278 {source="ncithesaurus:Rete_Testis"} xref: Wikipedia:Rete_testis is_a: UBERON:0004111 ! anatomical conduit is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005156 ! reproductive structure relationship: BFO:0000050 UBERON:0005051 ! part of mediastinum testis relationship: channel_for CL:0000019 ! sperm relationship: channels_from UBERON:0001343 ! seminiferous tubule of testis relationship: channels_into UBERON:0006946 ! efferent duct relationship: RO:0002202 UBERON:0005297 {source="Wikipedia"} ! develops from testis sex cord property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/b/b5/Hodenschema.svg" xsd:anyURI [Term] id: UBERON:0003967 name: cutaneous elastic tissue namespace: uberon def: "The slender connective tissue fiber in the extracellular matrix of skin tissue that is composed of microfibrils and amorphous elastin and is characterized by great elasticity." [MP:0008418] xref: EMAPA:37841 {source="MA:th"} is_a: UBERON:0002521 ! elastic tissue is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0002521 ! elastic tissue intersection_of: BFO:0000050 UBERON:0000014 ! part of zone of skin relationship: BFO:0000050 UBERON:0000014 ! part of zone of skin relationship: RO:0002433 UBERON:0000014 ! contributes to morphology of zone of skin [Term] id: UBERON:0003970 name: placental labyrinth vasculature namespace: uberon def: "Blood vessels of the layer of the placenta where embryonic and maternal blood vessels interdigitate." [MP:0008803] synonym: "placental labyrinth vascular network" EXACT [] synonym: "vasculature of placenta labyrinth" EXACT [] is_a: UBERON:0006876 ! vasculature of organ intersection_of: UBERON:0002049 ! vasculature intersection_of: BFO:0000050 UBERON:0003946 ! part of placenta labyrinth relationship: BFO:0000050 UBERON:0003946 ! part of placenta labyrinth [Term] id: UBERON:0003975 name: internal female genitalia namespace: uberon def: "The internal feminine genital organs, including the ovaries, uterine tubes, uterus, uterine cervix, and vagina." [MP:0009209] synonym: "female internal genitalia" EXACT [FMA:45654] synonym: "internal female genital organ" EXACT [BTO:0003099] synonym: "internal genitalia of female reproductive system" EXACT [OBOL:automatic] xref: BTO:0003099 xref: FMA:45654 xref: SCTID:303518005 is_a: UBERON:0003134 ! female reproductive organ is_a: UBERON:0004175 ! internal genitalia intersection_of: UBERON:0004175 ! internal genitalia intersection_of: BFO:0000050 UBERON:0000474 ! part of female reproductive system [Term] id: UBERON:0003978 name: valve namespace: uberon synonym: "anatomical valve" EXACT [FMA:67611] xref: EHDAA2:0004046 xref: EHDAA:1892 xref: EHDAA:4406 xref: FMA:67611 xref: galen:Valve is_a: UBERON:0000064 ! organ part relationship: RO:0002215 GO:0065008 ! capable of regulation of biological quality property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Heart.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Heart.glb" xsd:anyURI [Term] id: UBERON:0003983 name: conus arteriosus namespace: uberon def: "A conical pouch formed from the upper and left angle of the right ventricle in the chordate heart, from which the pulmonary artery arises[WP]. the anteriosuperior, smooth-walled portion of the cavity of the right ventricle, beginning at the supraventricular crest and terminates in the pulmonary trunk[MP]." [MP:0009464, Wikipedia:Conus_arteriosus] xref: AAO:0010250 xref: Wikipedia:Conus_arteriosus is_a: UBERON:0004151 ! cardiac chamber relationship: BFO:0000050 UBERON:0002080 ! part of heart right ventricle property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/4/46/Gray492.png" xsd:anyURI [Term] id: UBERON:0003984 name: uterine tube infundibulum namespace: uberon def: "The funnel-like expansion of the abdominal extremity of the uterine tube[MP]." [MP:0009466, Wikipedia:Infundibulum_of_uterine_tube] synonym: "infundibulum of oviduct" EXACT [FMA:18307] synonym: "infundibulum of uterine tube" EXACT [FMA:18307] xref: EMAPA:29897 xref: FMA:18307 xref: SCTID:362262001 xref: Wikipedia:Infundibulum_of_uterine_tube is_a: UBERON:0013515 {source="FMA"} ! subdivision of oviduct relationship: BFO:0000050 UBERON:0003889 {gci_filler="NCBITaxon:40674", gci_relation="BFO:0000050", source="FMA"} ! part of fallopian tube relationship: RO:0002160 NCBITaxon:7742 ! only in taxon Vertebrata property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/6/66/Illu_cervix.jpg" xsd:anyURI [Term] id: UBERON:0004015 name: embryonic-extraembryonic boundary namespace: uberon def: "The connection between the embryo proper and extraembryonic tissues." [MP:0003890] is_a: UBERON:0000015 ! non-material anatomical boundary intersection_of: UBERON:0000015 ! non-material anatomical boundary intersection_of: RO:0002220 UBERON:0000478 ! adjacent to extraembryonic structure intersection_of: RO:0002220 UBERON:0002050 ! adjacent to embryonic structure relationship: RO:0002220 UBERON:0000478 ! adjacent to extraembryonic structure relationship: RO:0002220 UBERON:0002050 ! adjacent to embryonic structure [Term] id: UBERON:0004016 name: dermatome namespace: uberon def: "A transitional population of migrating mesenchymal cells that derive from somites and that will become dermal cells." [AEO:0001017, AEO:JB] synonym: "cutis plate" EXACT [Wikipedia:Cutis_plate] synonym: "dermatomal mesenchyme" EXACT [Wikipedia:Cutis_plate] xref: AAO:0011028 xref: AEO:0001017 xref: EHDAA2_RETIRED:0003428 xref: EHDAA:1719 xref: EHDAA:1725 xref: EHDAA:1731 xref: EHDAA:1737 xref: EMAPA:32838 xref: FMA:295656 xref: NCIT:C61572 xref: UMLS:C0180383 {source="ncithesaurus:Dermatome"} xref: Wikipedia:Dermatome_(embryology) xref: XAO:0000220 is_a: UBERON:0017650 {source="AEO"} ! developing mesenchymal structure relationship: RO:0002202 UBERON:0004290 {source="EHDAA2-abduced"} ! develops from dermomyotome property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/f/f3/Gray64.png" xsd:anyURI [Term] id: UBERON:0004022 name: germinal neuroepithelium namespace: uberon def: "The single layer of epithelial cells that lines the early neural tube and develops into the nervous system and into the neural crest cells." [http://www.ncbi.nlm.nih.gov/books/NBK10047, MP:0004261] synonym: "germinal neuroepithelial layer" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "germinal neuroepithelium" EXACT [NCBIBook:NBK10047] synonym: "original neural tube" EXACT [NCBIBook:NBK10047] is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0010371 ! ecto-epithelium is_a: UBERON:0034706 {source="NCBIBook:NBK10047"} ! proliferating neuroepithelium disjoint_from: UBERON:0006934 ! sensory epithelium relationship: RO:0002007 UBERON:0001049 ! bounding layer of neural tube relationship: RO:0002220 UBERON:0003842 ! adjacent to neural tube lumen [Term] id: UBERON:0004027 name: chorionic plate namespace: uberon def: "That portion of the chorionic wall in the region of its uterine attachment, which gives rise to chorionic villi; it consists of the mesoderm that lines the chorionic vesicle and, on the maternal side, of the trophoblast that lines the intervillous spaces; in the last half of gestation, the mesodermal connective tissue is largely replaced by fibrinoid material, and the amnionic membrane is adherent to the fetal side of the plate." [http://www.medilexicon.com/medicaldictionary.php?t=69523, MP:0004560] xref: BTO:0002879 xref: EMAPA:31872 xref: NCIT:C34123 xref: SCTID:256391000 xref: UMLS:C0230972 {source="ncithesaurus:Chorionic_Plate"} is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005156 ! reproductive structure is_a: UBERON:0005292 ! extraembryonic tissue relationship: BFO:0000050 UBERON:0003124 ! part of chorion membrane relationship: BFO:0000050 UBERON:8600038 ! part of placental disc relationship: RO:0002433 UBERON:0003124 ! contributes to morphology of chorion membrane property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Placenta.glb" xsd:anyURI [Term] id: UBERON:0004053 name: external male genitalia namespace: uberon def: "The external masculine genital organs, including the penis and scrotum." [MP:0009199] synonym: "external male genital organ" EXACT [BTO:0003097] synonym: "male external genitalia" EXACT [FMA:45642] xref: BTO:0003097 xref: EMAPA:30977 xref: FMA:45642 xref: galen:MaleExternalGenitalia xref: SCTID:362264000 is_a: UBERON:0003135 ! male reproductive organ is_a: UBERON:0004176 ! external genitalia intersection_of: UBERON:0004176 ! external genitalia intersection_of: BFO:0000050 UBERON:0000079 ! part of male reproductive system disjoint_from: UBERON:0005056 ! external female genitalia disjoint_from: UBERON:0009196 ! indifferent external genitalia relationship: RO:0002433 UBERON:0000079 ! contributes to morphology of male reproductive system [Term] id: UBERON:0004054 name: internal male genitalia namespace: uberon def: "The internal masculine genital organs, including the testes, epididymides, deferent ducts, seminal vesicles, prostate, ejaculatory ducts, and bulbourethral glands." [MP:0009205] synonym: "internal male genital organ" EXACT [BTO:0003096] synonym: "male internal genitalia" EXACT [FMA:45655] xref: BTO:0003096 xref: FMA:45655 xref: SCTID:310536002 is_a: UBERON:0003135 ! male reproductive organ is_a: UBERON:0004175 ! internal genitalia intersection_of: UBERON:0004175 ! internal genitalia intersection_of: BFO:0000050 UBERON:0000079 ! part of male reproductive system relationship: RO:0002433 UBERON:0000079 ! contributes to morphology of male reproductive system [Term] id: UBERON:0004058 name: biliary ductule namespace: uberon def: "One of the fine terminal elements of the bile duct system, leaving the portal canal, and pursuing a course at the periphery of a lobule of the liver[BTO]. the excretory ducts of the liver that connect the interlobular ductules to the right or left hepatic duct[MP]." [BTO:0002840, MP:0009494] synonym: "bile ductule" EXACT [BTO:0002840] synonym: "biliary ductule" EXACT [http://www.mondofacto.com/facts/dictionary?ductuli+biliferi] synonym: "ductuli biliferi" EXACT [http://www.mondofacto.com/facts/dictionary?ductuli+biliferi] xref: BTO:0002840 xref: EMAPA:37440 {source="MA:th"} xref: TAO:0005164 xref: ZFA:0005164 is_a: UBERON:0000025 ! tube is_a: UBERON:0004119 ! endoderm-derived structure relationship: BFO:0000050 UBERON:0002107 ! part of liver relationship: BFO:0000050 UBERON:0002394 {source="BTO"} ! part of bile duct relationship: RO:0002220 UBERON:0001175 ! adjacent to common hepatic duct [Term] id: UBERON:0004060 name: neural tube ventricular layer namespace: uberon def: "The layer of undifferentiated, proliferating cells that line the neural tube lumen that is the immediate transformation of the germinal neuroepithelium." [http://www.ncbi.nlm.nih.gov/books/NBK10047, MP:0009689] synonym: "neural tube ependymal layer" EXACT [NCBIBook:NBK10047] synonym: "neural tube ventricular germinal zone" EXACT [NCBIBook:NBK10047] synonym: "neural tube ventricular zone" EXACT [MP:0009689] xref: EMAPA:17152 xref: EMAPA:35362 xref: EMAPA_RETIRED:16783 xref: MA:0003193 is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0010371 ! ecto-epithelium is_a: UBERON:0034706 {source="NCBIBook:NBK10047"} ! proliferating neuroepithelium relationship: BFO:0000050 UBERON:0001049 ! part of neural tube relationship: RO:0002220 UBERON:0003842 ! adjacent to neural tube lumen relationship: RO:0002495 UBERON:0004022 {source="NCBIBook:NBK10047"} ! immediate transformation of germinal neuroepithelium [Term] id: UBERON:0004061 name: neural tube mantle layer namespace: uberon def: "The layer of glia and differentiating neurons that forms as a second layer around the germinal neuroepithium; as this develops it comes to lie between the ventricular and marginal layers and includes the basal and alar plates. Develops into neurons and glia forming a gray matter layer." [http://www.ncbi.nlm.nih.gov/books/NBK10047, MP:0009690] synonym: "neural tube intermediate zone" EXACT [http://www.ncbi.nlm.nih.gov/books/NBK10047, MP:0009690] xref: EMAPA:17148 xref: EMAPA:35360 xref: neuronames:1367 is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0010371 ! ecto-epithelium is_a: UBERON:0034707 {source="NCBIBook:NBK10047"} ! differentiating neuroepithelium relationship: BFO:0000050 UBERON:0001049 ! part of neural tube relationship: RO:0002202 UBERON:0004022 ! develops from germinal neuroepithelium relationship: RO:0002220 UBERON:0004060 ! adjacent to neural tube ventricular layer relationship: RO:0002220 UBERON:0004062 ! adjacent to neural tube marginal layer [Term] id: UBERON:0004062 name: neural tube marginal layer namespace: uberon def: "The outermost layer of the neural tube that consists of axons from the developing mantle layer and will form the white matter." [http://www.ncbi.nlm.nih.gov/books/NBK10047, MP:0009691] synonym: "neural tube marginal zone" EXACT [MP:0009691] xref: EMAPA:17151 xref: neuronames:1368 is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0005162 ! multi cell part structure relationship: BFO:0000050 UBERON:0001049 ! part of neural tube relationship: RO:0002202 UBERON:0004061 ! develops from neural tube mantle layer relationship: RO:0002220 UBERON:0004061 ! adjacent to neural tube mantle layer [Term] id: UBERON:0004064 name: neural tube basal plate namespace: uberon def: "The region of the mantle layer of the neural tube that lies ventral to the sulcus limitans and contains primarily motor neurons and interneurons." [http://www.ncbi.nlm.nih.gov/books/NBK10047, MP:0009693, Wikipedia:Basal_plate_(neural_tube)] synonym: "basal plate" EXACT [] synonym: "basal plate of neural tube" EXACT [Wikipedia:Basal_plate_(neural_tube)] xref: AAO:0010561 xref: EFO:0001904 xref: NCIT:C34111 xref: neuronames:1372 xref: UMLS:C1511061 {source="ncithesaurus:Basal_Plate"} xref: Wikipedia:Basal_plate_(neural_tube) is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0005291 ! embryonic tissue relationship: BFO:0000050 UBERON:0004061 ! part of neural tube mantle layer relationship: BFO:0000051 CL:0000100 ! has part motor neuron relationship: BSPO:0000102 UBERON:0005478 ! ventral to sulcus limitans of neural tube relationship: RO:0002256 UBERON:0002328 ! developmentally induced by notochord relationship: RO:0002433 UBERON:0004061 ! contributes to morphology of neural tube mantle layer [Term] id: UBERON:0004066 name: frontonasal prominence namespace: uberon def: "The unpaired embryonic prominence that is formed by the tissues surrounding the forebrain vesicle and develops into the forehead and bridge of the nose/snout." [MP:0009901] synonym: "embryonic frontonasal prominence" EXACT [http://orcid.org/0000-0002-6601-2165] xref: EHDAA2:0000578 xref: EHDAA:4778 xref: EMAPA:16681 xref: FMA:293101 xref: NCIT:C34182 xref: SCTID:361486000 xref: UMLS:C1517321 {source="ncithesaurus:Frontonasal_Prominence"} xref: VHOG:0001319 xref: Wikipedia:Frontonasal_prominence is_a: UBERON:0009292 ! embryonic nasal process relationship: BSPO:0005001 UBERON:0000033 ! intersects midsagittal plane of head property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/9/98/Gray44.png" xsd:anyURI [Term] id: UBERON:0004068 name: medial nasal prominence namespace: uberon def: "The central area of the two limbs of a horseshoe-shaped mesenchymal swelling that lie medial to the olfactory placode or pit in the future nasal region of the embryo; it joins with the ipsilateral maxillary prominence in the formation of half of the upper jaw, and the nasal tip and philtrum of the upper lip develop from it." [MP:0009903, Wikipedia:Medial_nasal_prominence] synonym: "medial nasal process" EXACT [EHDAA2:0001076] synonym: "medial-nasal process" EXACT [EMAPA:16808] xref: EHDAA2:0001076 xref: EHDAA:4792 xref: EMAPA:16808 xref: FMA:295858 xref: SCTID:308877001 xref: VHOG:0000804 xref: Wikipedia:Medial_nasal_prominence is_a: UBERON:0009292 ! embryonic nasal process relationship: BFO:0000050 UBERON:0004066 {source="EHDAA2"} ! part of frontonasal prominence relationship: BSPO:0000126 UBERON:0008816 ! in lateral side of embryonic head relationship: RO:0002202 UBERON:0004066 {source="Wikipedia"} ! develops from frontonasal prominence property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/8/85/Gray45.png" xsd:anyURI [Term] id: UBERON:0004087 name: vena cava namespace: uberon def: "Any of the veins that carries deoxygenated blood from a part of the body into the right atrium of the heart." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Venae_cavae] xref: AAO:0010215 xref: BTO:0001438 xref: EMAPA:18415 xref: FMA:321896 xref: GAID:547 xref: MA:0000068 xref: MESH:D014684 xref: NCIT:C12817 xref: SCTID:244405007 xref: UMLS:C0042460 {source="ncithesaurus:Vena_Cava"} xref: Wikipedia:Venae_cavae is_a: UBERON:0003479 ! thoracic cavity vein is_a: UBERON:0013768 ! great vessel of heart property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/3/35/Relations_of_the_aorta,_trachea,_esophagus_and_other_heart_structures.png" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI property_value: x_0.1:depiction "https://upload.wikimedia.org/wikipedia/commons/7/7c/Heart_numlabels.png" xsd:anyURI [Term] id: UBERON:0004088 name: orbital region namespace: uberon def: "The subdivision of the face that includes the eye (eyeball plus adnexa such as eyelids) and the orbit of the skull and associated parts of the face such as the eyebrows, if present." [http://orcid.org/0000-0002-6601-2165] synonym: "content of orbital part of eye" EXACT [FMA:260119] synonym: "eye region" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "orbital part of face" EXACT [http://orcid.org/0000-0002-6601-2165] xref: FMA:260119 is_a: UBERON:0001444 ! subdivision of head relationship: BFO:0000050 UBERON:0001456 ! part of face [Term] id: UBERON:0004089 name: midface namespace: uberon def: "The middle of the face including the nose and its associated bony structures[MW]." [HP:0000309, http://www.merriam-webster.com/medical/midface] xref: EMAPA:32806 xref: FMA:285406 xref: MA:0001910 is_a: UBERON:0001444 ! subdivision of head relationship: BFO:0000050 UBERON:0001456 ! part of face relationship: RO:0002160 NCBITaxon:89593 ! only in taxon Craniata relationship: RO:0002433 UBERON:0001456 ! contributes to morphology of face [Term] id: UBERON:0004100 name: renal collecting system namespace: uberon def: "The collecting duct system of the kidney consists of a series of tubules and ducts that connect the nephrons to the ureter. It participates in electrolyte and fluid balance through reabsorption and excretion, processes regulated by the hormones aldosterone and antidiuretic hormone." [HP:0004742, Wikipedia:Collecting_duct_system] synonym: "collecting duct system" EXACT [Wikipedia:Collecting_duct_system] synonym: "kidney collecting duct system" EXACT [Wikipedia:Collecting_duct_system] xref: FMA:265239 xref: SCTID:279371005 xref: Wikipedia:Collecting_duct_system is_a: UBERON:0000467 ! anatomical system relationship: BFO:0000050 UBERON:0002113 ! part of kidney property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png" xsd:anyURI [Term] id: UBERON:0004111 name: anatomical conduit namespace: uberon def: "Any tube, opening or passage that connects two distinct anatomical spaces." [http://orcid.org/0000-0002-6601-2165] xref: AEO:0000080 xref: EHDAA2:0003080 xref: FMA:242873 xref: SCTID:346902003 xref: Wikipedia:Foramen is_a: UBERON:0010000 ! multicellular anatomical structure intersection_of: UBERON:0010000 ! multicellular anatomical structure intersection_of: BFO:0000051 UBERON:0013686 ! has part anatomical conduit space intersection_of: RO:0002570 UBERON:0000061 ! conduit for anatomical structure relationship: BFO:0000051 UBERON:0013686 ! has part anatomical conduit space relationship: RO:0002176 UBERON:0000464 {cardinality="2"} ! connects anatomical space relationship: RO:0002176 UBERON:0000464 ! connects anatomical space relationship: RO:0002570 UBERON:0000061 ! conduit for anatomical structure [Term] id: UBERON:0004118 name: vasculature of iris namespace: uberon def: "A vasculature that is part of a iris [Automatically generated definition]." [OBOL:automatic] synonym: "iris blood vessels" EXACT [ZFA:0005568] synonym: "iris vascular network" EXACT [OBOL:automatic] synonym: "iris vasculature" EXACT [] synonym: "vascular network of iris" EXACT [OBOL:automatic] xref: ZFA:0005568 is_a: UBERON:0002203 ! vasculature of eye intersection_of: UBERON:0002049 ! vasculature intersection_of: BFO:0000050 UBERON:0001769 ! part of iris relationship: BFO:0000050 UBERON:0001769 ! part of iris [Term] id: UBERON:0004119 name: endoderm-derived structure namespace: uberon def: "An anatomical structure that develops (entirely or partially) from the endoderm." [https://orcid.org/0000-0002-6601-2165] is_a: UBERON:0000061 ! anatomical structure intersection_of: UBERON:0000061 ! anatomical structure intersection_of: RO:0002202 UBERON:0000925 ! develops from endoderm relationship: RO:0002202 UBERON:0000925 ! develops from endoderm property_value: IAO:0000232 "Grouping term for query purposes" xsd:string [Term] id: UBERON:0004120 name: mesoderm-derived structure namespace: uberon def: "An anatomical structure that develops (entirely or partially) from the mesoderm." [https://orcid.org/0000-0002-6601-2165] synonym: "mesodermal derivative" EXACT [FBbt:00025998] is_a: UBERON:0000061 ! anatomical structure intersection_of: UBERON:0000061 ! anatomical structure intersection_of: RO:0002202 UBERON:0000926 ! develops from mesoderm relationship: RO:0002202 UBERON:0000926 ! develops from mesoderm property_value: IAO:0000232 "Grouping term for query purposes" xsd:string [Term] id: UBERON:0004121 name: ectoderm-derived structure namespace: uberon def: "An anatomical structure that develops (entirely or partially) from the ectoderm." [https://orcid.org/0000-0002-6601-2165] synonym: "ectodermal deriviative" EXACT [FBbt:00025990] is_a: UBERON:0000061 ! anatomical structure intersection_of: UBERON:0000061 ! anatomical structure intersection_of: RO:0002202 UBERON:0000924 ! develops from ectoderm relationship: RO:0002202 UBERON:0000924 ! develops from ectoderm property_value: IAO:0000232 "Grouping term for query purposes" xsd:string [Term] id: UBERON:0004122 name: genitourinary system namespace: uberon def: "Anatomical system that has as its parts the organs concerned with the production and excretion of urine and those concerned with reproduction." [VHOG:0000286] synonym: "urogenital system" EXACT [] xref: AAO:0000624 xref: BILA:0000122 xref: BTO:0003091 xref: EFO:0003864 xref: EHDAA:1013 xref: EMAPA:16367 xref: EV:0100094 xref: FMA:280610 xref: GAID:362 xref: galen:GenitoUrinarySystem xref: MESH:D014566 xref: NCIT:C12810 xref: SCTID:278861008 xref: UMLS:C0042066 {source="ncithesaurus:Genitourinary_System"} xref: VHOG:0000286 xref: XAO:0000140 is_a: UBERON:0000467 ! anatomical system intersection_of: UBERON:0000467 ! anatomical system intersection_of: BFO:0000051 UBERON:0000990 ! has part reproductive system intersection_of: BFO:0000051 UBERON:0001008 ! has part renal system relationship: BFO:0000051 UBERON:0000990 ! has part reproductive system relationship: BFO:0000051 UBERON:0001008 ! has part renal system relationship: RO:0002202 UBERON:0003064 {gci_filler="NCBITaxon:7742", gci_relation="BFO:0000050", source="AAO", source="https://github.com/geneontology/go-ontology/issues/16143"} ! develops from intermediate mesoderm relationship: RO:0002492 UBERON:0000066 ! existence ends during fully formed stage [Term] id: UBERON:0004123 name: myocardial layer namespace: uberon def: "Any of the layers of the myocardium. Example: compact layer, trabecular layer." [http://orcid.org/0000-0002-6601-2165] synonym: "layer of myocardium" EXACT [] synonym: "myocardium layer" EXACT [] xref: EMAPA:37475 {source="MA:th"} xref: MA:0000080 is_a: UBERON:0005983 ! heart layer intersection_of: UBERON:0004923 ! organ component layer intersection_of: layer_part_of UBERON:0002349 ! myocardium relationship: layer_part_of UBERON:0002349 ! myocardium [Term] id: UBERON:0004124 name: myocardium trabecular layer namespace: uberon def: "The layer of the myocardium composed of projections of contractile myocytes. The trabecular layer is bounded internally by the endocardium. In zebrafish, unlike the trabeculations of higher vertebrates, both atrial and ventricular trabeculae have more strut-like character, and are more uniform without apparent regional differences[ZFA]." [ZFA:0005059] synonym: "myocardial trabecular layer" EXACT [] synonym: "trabecular layer" EXACT [ZFA:0005059] xref: EFO:0003706 xref: MA:0002866 xref: TAO:0005059 xref: ZFA:0005059 is_a: UBERON:0004123 ! myocardial layer intersection_of: UBERON:0004123 ! myocardial layer intersection_of: RO:0002220 UBERON:0002165 ! adjacent to endocardium intersection_of: RO:0002473 GO:0036194 ! composed primarily of muscle cell projection relationship: RO:0002220 UBERON:0002165 ! adjacent to endocardium relationship: RO:0002473 GO:0036194 ! composed primarily of muscle cell projection [Term] id: UBERON:0004126 name: trabecular layer of ventricle namespace: uberon def: "A myocardium trabecular layer that is part of a cardiac ventricle." [OBOL:automatic] synonym: "myocardium of region of ventricle" EXACT [FMA:83511] synonym: "trabecular cardiac ventricle muscle" EXACT [GO:0003222] synonym: "ventricular trabecular myocardium" EXACT [GO:0003222] xref: FMA:83511 xref: TAO:0005060 xref: ZFA:0005060 is_a: UBERON:0004124 ! myocardium trabecular layer intersection_of: UBERON:0004124 ! myocardium trabecular layer intersection_of: BFO:0000050 UBERON:0002082 ! part of cardiac ventricle relationship: BFO:0000050 UBERON:0001083 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! part of myocardium of ventricle [Term] id: UBERON:0004128 name: optic vesicle namespace: uberon def: "The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup[GO]. Portion of tissue that is comprised of neuroepitheium which has pinched off from the anterior neural keel and will form the optic cup[ZFA]." [GO:0003404, Wikipedia:Optic_vesicles] xref: AAO:0011039 xref: EHDAA2:0001320 xref: EMAPA:16540 xref: FMA:293357 xref: NCIT:C34236 xref: SCTID:362864008 xref: TAO:0000050 xref: UMLS:C0231106 {source="ncithesaurus:Optic_Vesicle"} xref: VHOG:0000165 xref: Wikipedia:Optic_vesicles xref: XAO:0000228 xref: ZFA:0000050 is_a: UBERON:0000479 ! tissue is_a: UBERON:0004121 ! ectoderm-derived structure relationship: BFO:0000050 UBERON:0010312 {source="ZFA"} ! part of immature eye relationship: RO:0002202 UBERON:0002346 {source="GO-def"} ! develops from neurectoderm relationship: RO:0002202 UBERON:0003071 {source="ZFA"} ! develops from eye primordium relationship: RO:0002256 UBERON:0004880 ! developmentally induced by chordamesoderm property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/e/e0/Gray863.png" xsd:anyURI [Term] id: UBERON:0004133 name: salivatory nucleus namespace: uberon def: "Missing definition for term UBERON:0004133. Please replace it using linked reference." [GO:0021751] synonym: "salivary nucleus" EXACT [GO:0021751] is_a: UBERON:0006331 ! brainstem nucleus is_a: UBERON:0009662 ! hindbrain nucleus relationship: BFO:0000050 UBERON:0000988 ! part of pons [Term] id: UBERON:0004139 name: cardiogenic plate namespace: uberon def: "The first recognizable structure derived from the heart field." [GO:0003142] synonym: "myocardial plate" EXACT [EHDAA2:0000215] xref: EHDAA2:0000215 xref: EMAPA:16106 xref: VHOG:0000975 is_a: UBERON:0002050 ! embryonic structure relationship: RO:0002202 UBERON:0003084 ! develops from heart primordium [Term] id: UBERON:0004140 name: primary heart field namespace: uberon def: "A specific region of the lateral mesoderm that will form the primary beating heart tube. In mammals the primary heart field gives rise to the left ventricle." [GO:0003138, GOC:mtg_heart, GOC:rl] synonym: "first heart field" EXACT [XAO:0004185] synonym: "primary heart field" EXACT [PMID:17276708, XAO:0004185] xref: XAO:0004185 is_a: UBERON:0002050 ! embryonic structure is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0007688 ! anlage relationship: BFO:0000050 UBERON:0003081 {source="GO:0003128"} ! part of lateral plate mesoderm relationship: BFO:0000050 UBERON:0036146 {source="https://orcid.org/0000-0003-3308-6245"} ! part of cardiopharyngeal field [Term] id: UBERON:0004141 name: heart tube namespace: uberon def: "An epithelial tube that will give rise to the mature heart." [GO:0003143, GOC:mtg_heart] synonym: "embryonic heart tube" EXACT [GO:0003143] synonym: "endocardial heart tube" EXACT [MP:0012700] synonym: "endocardial tube" EXACT [XAO:0000337] xref: AAO:0010411 xref: EFO:0003526 xref: EMAPA:32685 xref: NCIT:C34161 xref: TAO:0000360 xref: XAO:0000337 xref: ZFA:0000360 is_a: UBERON:0003914 ! epithelial tube is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0012275 ! meso-epithelium relationship: RO:0002495 UBERON:0005498 {source="ZFA-modified"} ! immediate transformation of primitive heart tube [Term] id: UBERON:0004142 name: outflow tract septum namespace: uberon def: "The outflow tract septum is a partition in the outflow tract." [GO:0003148] xref: XAO:0004141 is_a: UBERON:0002099 ! cardiac septum intersection_of: UBERON:0002099 ! cardiac septum intersection_of: BFO:0000050 UBERON:0004145 ! part of outflow tract relationship: BFO:0000050 UBERON:0004145 ! part of outflow tract [Term] id: UBERON:0004145 name: outflow tract namespace: uberon def: "The outflow tract is the portion of the heart through which blood flows into the arteries." [GO:0003151] synonym: "cardiac outflow tract" EXACT [PMID:20735616] synonym: "heart outflow tract" EXACT [] xref: EHDAA2:0001351 xref: EHDAA:464 xref: EHDAA:798 xref: EMAPA:16346 xref: MA:0000100 xref: VHOG:0000670 xref: XAO:0004139 is_a: UBERON:0004111 ! anatomical conduit is_a: UBERON:0004120 ! mesoderm-derived structure relationship: BFO:0000050 UBERON:0000948 ! part of heart relationship: channel_for UBERON:0000178 ! blood relationship: channels_from UBERON:0000948 ! heart relationship: channels_into UBERON:0001637 ! artery [Term] id: UBERON:0004146 name: His-Purkinje system namespace: uberon def: "The His-Purkinje system receives signals from the AV node and is composed of the fibers that regulate cardiac muscle contraction in the ventricles." [GO:0003164, https://github.com/geneontology/go-ontology/issues/12451] synonym: "His-Purkinji network" EXACT [] synonym: "VCS" EXACT [] synonym: "ventricular conduction system" EXACT [] is_a: UBERON:0010131 {source="cjm"} ! conducting tissue of heart is_a: UBERON:0018649 ! cardiac muscle tissue of ventricle relationship: BFO:0000050 UBERON:0002350 {source="GO"} ! part of conducting system of heart relationship: RO:0002160 NCBITaxon:32523 {source="PMID:12626327", source="PMID:21234997", source="github:michaelerice"} ! only in taxon Tetrapoda [Term] id: UBERON:0004148 name: cardiac vein namespace: uberon def: "Vein of heart that drains the myocardium." [http://orcid.org/0000-0002-6601-2165] synonym: "cardiac vein" EXACT [FMA:12846] synonym: "coronary vein" EXACT [ZFA:0005814] synonym: "heart vein" EXACT [OBOL:automatic] synonym: "vein of heart" EXACT [OBOL:automatic] xref: EHDAA2:0004507 xref: EMAPA:37137 {source="MA:th"} xref: FMA:12846 xref: galen:CoronaryVein xref: NCIT:C12878 xref: NCIT:C12882 xref: SCTID:277726009 xref: UMLS:C0226654 {source="ncithesaurus:Cardiac_Vein"} xref: UMLS:C0226737 {source="ncithesaurus:Coronary_Vein"} xref: Wikipedia:Coronary_circulation xref: ZFA:0005814 is_a: UBERON:0003498 ! heart blood vessel is_a: UBERON:0005194 ! thoracic vein is_a: UBERON:0013140 {source="FMA"} ! systemic vein intersection_of: UBERON:0001638 ! vein intersection_of: BFO:0000050 UBERON:0000948 ! part of heart intersection_of: RO:0002179 UBERON:0002349 ! drains myocardium relationship: BFO:0000050 RO:0002577 ! part of system relationship: RO:0002179 UBERON:0002349 ! drains myocardium property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI property_value: x_0.1:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI [Term] id: UBERON:0004151 name: cardiac chamber namespace: uberon def: "A cardiac chamber surrounds an enclosed cavity within the heart." [GO:0003205] synonym: "chamber of heart" EXACT [] synonym: "heart chamber" EXACT [] xref: FMA:7095 xref: SCTID:276456008 is_a: UBERON:0000064 ! organ part is_a: UBERON:0004120 ! mesoderm-derived structure relationship: BFO:0000050 UBERON:0000948 ! part of heart [Term] id: UBERON:0004160 name: proepicardium namespace: uberon def: "An embryonic group of progenitor cells that forms from an outpouching of the septum transversum near the venous pole of the heart and gives rise to the epicardium." [GO:0003342, http://en.wiktionary.org/wiki/proepicardium] synonym: "proepicardial cluster" EXACT [ZFA:0005808] synonym: "proepicardial organ" EXACT [ZFIN:ZDB-PUB-080218-16] xref: EMAPA:36025 xref: ZFA:0005808 is_a: UBERON:0003104 ! mesenchyme relationship: BFO:0000050 UBERON:0004161 ! part of septum transversum relationship: BFO:0000050 UBERON:0004535 {source="ZFA"} ! part of cardiovascular system [Term] id: UBERON:0004161 name: septum transversum namespace: uberon def: "A thick plate of mesodermal tissue that occupies the space between the thoracic cavity and yolk stalk in the early embryo, forming a transverse partition partially separating the coelomic cavity into thoracic and abdominal portions. It gives rise to the central tendon of the diaphragm[VHOG]." [VHOG:0000019, Wikipedia:Septum_transversum] synonym: "transverse septum" EXACT [https://orcid.org/0000-0002-6601-2165] xref: EHDAA2:0001829 xref: EHDAA:736 xref: EMAPA:16318 xref: FMA:295593 xref: NCIT:C34296 xref: SCTID:308819008 xref: UMLS:C0231004 {source="ncithesaurus:Septum_Transversum"} xref: VHOG:0000019 xref: Wikipedia:Septum_transversum is_a: UBERON:0003104 ! mesenchyme relationship: BFO:0000050 UBERON:0002100 ! part of trunk relationship: RO:0001025 UBERON:0002323 ! located in coelemic cavity lumen [Term] id: UBERON:0004175 name: internal genitalia namespace: uberon def: "The internal genitalia are the internal sex organs such as the uterine tube, the uterus and the vagina in female mammals, and the testis, seminal vesicle, ejaculatory duct and prostate in male mammals." [GO:0035260] synonym: "internal genitalia" EXACT [] synonym: "internal genitals" EXACT [] xref: FMA:45652 is_a: UBERON:0003133 ! reproductive organ [Term] id: UBERON:0004176 name: external genitalia namespace: uberon def: "The external genitalia are the outer sex organs, such as the penis or vulva in mammals." [GO:0035261] synonym: "external genitalia" EXACT [] xref: FMA:45643 xref: SCTID:362207005 is_a: UBERON:0003133 ! reproductive organ [Term] id: UBERON:0004177 name: hemopoietic organ namespace: uberon def: "Organ that is part of the hematopoietic system." [GOC:Obol] synonym: "haematological system organ" EXACT [OBOL:automatic] synonym: "haemopoietic system organ" EXACT [OBOL:automatic] synonym: "hematopoeitic organ" EXACT [] synonym: "hematopoietic system organ" EXACT [OBOL:automatic] synonym: "organ of haematological system" EXACT [OBOL:automatic] synonym: "organ of haemopoietic system" EXACT [OBOL:automatic] synonym: "organ of hematopoietic system" EXACT [OBOL:automatic] synonym: "organ of organa haemopoietica" EXACT [OBOL:automatic] synonym: "organa haemopoietica organ" EXACT [OBOL:automatic] xref: BTO:0004605 xref: EMAPA:37665 {source="MA:th"} xref: FMA:7143 xref: MA:0000747 xref: SCTID:361338006 is_a: UBERON:0000062 ! organ is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0000062 ! organ intersection_of: BFO:0000050 UBERON:0002390 ! part of hematopoietic system relationship: BFO:0000050 UBERON:0002390 ! part of hematopoietic system [Term] id: UBERON:0004178 name: aorta smooth muscle tissue namespace: uberon def: "The nonstriated, involuntary muscle tissue located in the wall of the aorta." [MGI:csmith, MP:0009865] synonym: "aorta non-striated muscle" EXACT [OBOL:automatic] synonym: "aorta smooth muscle" EXACT [OBOL:automatic] synonym: "aortic smooth muscle" EXACT [BTO:0001685] xref: BTO:0001685 xref: CALOHA:TS-0048 xref: EFO:0002775 xref: EMAPA:35135 xref: MA:0000702 xref: NCIT:C49191 xref: UMLS:C1706825 {source="ncithesaurus:Aorta_Smooth_Muscle_Tissue"} is_a: UBERON:0004237 ! blood vessel smooth muscle is_a: UBERON:0004695 ! arterial system smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: BFO:0000050 UBERON:0000947 ! part of aorta relationship: BFO:0000050 UBERON:0000947 ! part of aorta [Term] id: UBERON:0004183 name: placental labyrinth blood vessel namespace: uberon def: "The embryonic vessels grow through the layer to come in close contact with the maternal blood supply." [GO:0060716] synonym: "blood vessel of labyrinthine layer" EXACT [OBOL:automatic] synonym: "blood vessel of labyrinthine layer of placenta" EXACT [OBOL:automatic] synonym: "blood vessel of placenta labyrinth" EXACT [OBOL:automatic] synonym: "labyrinthine layer blood vessel" EXACT [GO:0060716] synonym: "labyrinthine layer of placenta blood vessel" EXACT [OBOL:automatic] synonym: "placenta labyrinth blood vessel" EXACT [OBOL:automatic] is_a: UBERON:0022358 ! placenta blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: BFO:0000050 UBERON:0003946 ! part of placenta labyrinth relationship: BFO:0000050 UBERON:0003970 ! part of placental labyrinth vasculature [Term] id: UBERON:0004185 name: endodermal part of digestive tract namespace: uberon def: "A portions of the gut that is derived from endoderm." [GO:0061031] synonym: "endodermal gut" EXACT [] synonym: "gut endoderm" EXACT [EMAPA:32930] xref: EMAPA:32930 is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0004921 ! subdivision of digestive tract intersection_of: UBERON:0004921 ! subdivision of digestive tract intersection_of: BFO:0000050 UBERON:0001555 ! part of digestive tract intersection_of: RO:0002202 UBERON:0000925 ! develops from endoderm [Term] id: UBERON:0004203 name: cortical collecting duct namespace: uberon def: "The cortical collecting duct is the portion of the collecting duct that resides in the renal cortex." [GO:0072059] synonym: "kidney cortex collecting duct" EXACT [MA:0002600] xref: BTO:0002643 xref: EMAPA:28130 xref: MA:0002600 is_a: UBERON:0013522 ! subdivision of tube intersection_of: UBERON:0013522 ! subdivision of tube intersection_of: BFO:0000050 UBERON:0001225 ! part of cortex of kidney intersection_of: BFO:0000050 UBERON:0001232 ! part of collecting duct of renal tubule relationship: BFO:0000050 UBERON:0001225 ! part of cortex of kidney relationship: BFO:0000050 UBERON:0001232 ! part of collecting duct of renal tubule [Term] id: UBERON:0004208 name: nephrogenic mesenchyme namespace: uberon def: "Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron." [GO:0072076] synonym: "mesenchyme of nephron" EXACT [OBOL:automatic] synonym: "nephron mesenchyme" EXACT [OBOL:automatic] is_a: UBERON:0003104 ! mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: RO:0002387 UBERON:0001285 ! has potential to develop into nephron relationship: RO:0002387 UBERON:0001285 ! has potential to develop into nephron [Term] id: UBERON:0004209 name: renal vesicle namespace: uberon def: "The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells." [GO:0072077] synonym: "stage I nephron" EXACT [http://www.gudmap.org/Organ_Summaries/Metanephros/Renal_vesicle.html, ZFA:0005586] is_a: UBERON:0007503 {source="EHDAA2"} ! epithelial vesicle relationship: BFO:0000050 UBERON:0010536 ! part of nephron progenitor relationship: RO:0002202 UBERON:0004208 ! develops from nephrogenic mesenchyme relationship: RO:0002256 UBERON:0000084 ! developmentally induced by ureteric bud relationship: RO:0002387 UBERON:0004211 ! has potential to develop into nephron epithelium [Term] id: UBERON:0004211 name: nephron epithelium namespace: uberon def: "The nephron epithelium is a tissue that covers the surface of a nephron." [GO:0072088] synonym: "epithelial tissue of nephron" EXACT [OBOL:automatic] synonym: "epithelium of nephron" EXACT [OBOL:automatic] synonym: "nephron epithelial tissue" EXACT [OBOL:automatic] is_a: UBERON:0004819 ! kidney epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: BFO:0000050 UBERON:0001285 ! part of nephron relationship: BFO:0000050 UBERON:0001285 ! part of nephron [Term] id: UBERON:0004215 name: back nerve namespace: uberon def: "A nerve that is part of a back [Automatically generated definition]." [OBOL:automatic] synonym: "nerve of back" EXACT [OBOL:automatic] xref: EMAPA:37268 {source="MA:th"} xref: MA:0000497 is_a: UBERON:0001021 ! nerve intersection_of: UBERON:0001021 ! nerve intersection_of: BFO:0000050 UBERON:0001137 ! part of dorsum relationship: BFO:0000050 UBERON:0001137 ! part of dorsum [Term] id: UBERON:0004219 name: urethra smooth muscle layer namespace: uberon def: "A portion of smooth muscle tissue that is part of a urethra [Automatically generated definition]." [OBOL:automatic] synonym: "muscle layer of urethra" EXACT [FMA:76909] synonym: "muscular coat of urethra" EXACT [FMA:76909] synonym: "muscular layer of urethra" EXACT [FMA:76909] synonym: "smooth muscle of urethra" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of urethra" EXACT [OBOL:automatic] synonym: "urethra smooth muscle tissue" EXACT [OBOL:automatic] xref: EMAPA:36630 xref: FMA:76909 xref: MA:0001691 is_a: UBERON:0001135 ! smooth muscle tissue intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: BFO:0000050 UBERON:0000057 ! part of urethra relationship: BFO:0000050 UBERON:0000057 ! part of urethra [Term] id: UBERON:0004220 name: large intestine smooth muscle namespace: uberon def: "A portion of smooth muscle tissue that is part of a large intestine [Automatically generated definition]." [OBOL:automatic] synonym: "involuntary muscle of large intestine" EXACT [OBOL:automatic] synonym: "large intestine involuntary muscle" EXACT [OBOL:automatic] synonym: "large intestine non-striated muscle" EXACT [OBOL:automatic] synonym: "large intestine smooth muscle tissue" EXACT [OBOL:automatic] synonym: "non-striated muscle of large intestine" EXACT [OBOL:automatic] synonym: "smooth muscle of large intestine" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of large intestine" EXACT [OBOL:automatic] xref: EMAPA:35469 xref: MA:0001547 is_a: UBERON:0004221 ! intestine smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: BFO:0000050 UBERON:0000059 ! part of large intestine relationship: BFO:0000050 UBERON:0001169 {source="MA"} ! part of wall of large intestine relationship: RO:0002131 UBERON:0011198 ! overlaps muscle layer of large intestine [Term] id: UBERON:0004221 name: intestine smooth muscle namespace: uberon def: "A portion of smooth muscle tissue that is part of a intestine [Automatically generated definition]." [OBOL:automatic] synonym: "bowel involuntary muscle" EXACT [OBOL:automatic] synonym: "bowel non-striated muscle" EXACT [OBOL:automatic] synonym: "bowel smooth muscle" EXACT [OBOL:automatic] synonym: "bowel smooth muscle tissue" EXACT [OBOL:automatic] synonym: "intestine involuntary muscle" EXACT [OBOL:automatic] synonym: "intestine non-striated muscle" EXACT [OBOL:automatic] synonym: "intestine smooth muscle tissue" EXACT [OBOL:automatic] synonym: "involuntary muscle of bowel" EXACT [OBOL:automatic] synonym: "involuntary muscle of intestine" EXACT [OBOL:automatic] synonym: "non-striated muscle of bowel" EXACT [OBOL:automatic] synonym: "non-striated muscle of intestine" EXACT [OBOL:automatic] synonym: "smooth muscle of bowel" EXACT [OBOL:automatic] synonym: "smooth muscle of intestine" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of bowel" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of intestine" EXACT [OBOL:automatic] xref: BTO:0000643 xref: EMAPA:35441 xref: EMAPA:35443 xref: MA:0001539 xref: NCIT:C49243 xref: UMLS:C1708547 {source="ncithesaurus:Intestinal_Smooth_Muscle_Tissue"} is_a: UBERON:0004226 ! gastrointestinal system smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: BFO:0000050 UBERON:0000160 ! part of intestine relationship: BFO:0000050 UBERON:0001262 ! part of wall of intestine relationship: RO:0002131 UBERON:0012367 ! overlaps muscle layer of intestine relationship: RO:0002433 UBERON:0000160 ! contributes to morphology of intestine [Term] id: UBERON:0004222 name: stomach smooth muscle namespace: uberon def: "A portion of smooth muscle tissue that is part of a stomach [Automatically generated definition]." [OBOL:automatic] synonym: "involuntary muscle of stomach" EXACT [OBOL:automatic] synonym: "involuntary muscle of ventriculus" EXACT [OBOL:automatic] synonym: "non-striated muscle of stomach" EXACT [OBOL:automatic] synonym: "non-striated muscle of ventriculus" EXACT [OBOL:automatic] synonym: "smooth muscle of stomach" EXACT [OBOL:automatic] synonym: "smooth muscle of ventriculus" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of stomach" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of ventriculus" EXACT [OBOL:automatic] synonym: "stomach involuntary muscle" EXACT [OBOL:automatic] synonym: "stomach non-striated muscle" EXACT [OBOL:automatic] synonym: "stomach smooth muscle tissue" EXACT [OBOL:automatic] synonym: "ventriculus involuntary muscle" EXACT [OBOL:automatic] synonym: "ventriculus non-striated muscle" EXACT [OBOL:automatic] synonym: "ventriculus smooth muscle" EXACT [OBOL:automatic] synonym: "ventriculus smooth muscle tissue" EXACT [OBOL:automatic] xref: BTO:0001818 xref: EMAPA:35823 xref: MA:0001627 is_a: UBERON:0004226 ! gastrointestinal system smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: BFO:0000050 UBERON:0000945 ! part of stomach relationship: BFO:0000050 UBERON:0001167 ! part of wall of stomach [Term] id: UBERON:0004224 name: muscular coat of vas deferens namespace: uberon def: "A muscular coat that is part of a vas deferens [Automatically generated definition]." [OBOL:automatic] synonym: "muscle layer of deferent duct" EXACT [FMA:19239] synonym: "muscle layer of ductus deferens" EXACT [FMA:19239] synonym: "muscle layer of vas deferens" EXACT [FMA:19239] synonym: "muscular coat of ductus deferens" EXACT [FMA:19239] synonym: "muscular layer of ductus deferens" EXACT [FMA:19239] synonym: "muscularis of vas deferens" EXACT [FMA:19239] synonym: "tunica muscularis (ductus deferens)" EXACT [FMA:19239] xref: EMAPA:29270 xref: FMA:19239 xref: MA:0001750 xref: SCTID:299705008 is_a: UBERON:0005156 ! reproductive structure is_a: UBERON:0006660 ! muscular coat is_a: UBERON:0034933 ! layer of smooth muscle tissue intersection_of: UBERON:0006660 ! muscular coat intersection_of: BFO:0000050 UBERON:0001000 ! part of vas deferens relationship: BFO:0000050 UBERON:0001000 ! part of vas deferens [Term] id: UBERON:0004225 name: respiratory system smooth muscle namespace: uberon def: "A portion of smooth muscle tissue that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "respiratory smooth muscle" EXACT [BTO:0001660] synonym: "smooth muscle of respiratory system" EXACT [OBOL:automatic] xref: BTO:0001660 xref: EMAPA:35734 xref: MA:0001830 is_a: UBERON:0001135 ! smooth muscle tissue intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: BFO:0000050 UBERON:0001004 ! part of respiratory system relationship: BFO:0000050 UBERON:0001004 ! part of respiratory system [Term] id: UBERON:0004226 name: gastrointestinal system smooth muscle namespace: uberon def: "A portion of smooth muscle tissue that is part of a digestive system [Automatically generated definition]." [OBOL:automatic] synonym: "smooth muscle tissue of gastrointestinal system" EXACT [OBOL:automatic] xref: EMAPA:35117 xref: MA:0001523 is_a: UBERON:0001135 ! smooth muscle tissue intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: BFO:0000050 UBERON:0005409 ! part of alimentary part of gastrointestinal system relationship: BFO:0000050 UBERON:0005409 ! part of alimentary part of gastrointestinal system [Term] id: UBERON:0004227 name: kidney pelvis smooth muscle namespace: uberon def: "The smooth muscle tissue surrounding the urothelium of the kidney pelvis." [MGI:csmith, MP:0011335] synonym: "kidney pelvis smooth muscle" EXACT [EMAPA:28120] synonym: "renal pelvis smooth muscle" EXACT [EMAPA:28120] synonym: "smooth muscle tissue of renal pelvis" EXACT [FMA:262022] xref: EMAPA:28120 xref: FMA:262022 xref: MA:0002631 is_a: UBERON:0001135 ! smooth muscle tissue intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: BFO:0000050 UBERON:0001224 ! part of renal pelvis relationship: BFO:0000050 UBERON:0001224 ! part of renal pelvis relationship: RO:0002433 UBERON:0001224 ! contributes to morphology of renal pelvis [Term] id: UBERON:0004228 name: urinary bladder smooth muscle namespace: uberon def: "A portion of smooth muscle tissue that is part of a urinary bladder [Automatically generated definition]." [OBOL:automatic] synonym: "bladder involuntary muscle" EXACT [OBOL:automatic] synonym: "bladder non-striated muscle" EXACT [OBOL:automatic] synonym: "bladder smooth muscle" EXACT [OBOL:automatic] synonym: "bladder smooth muscle tissue" EXACT [OBOL:automatic] synonym: "involuntary muscle of bladder" EXACT [OBOL:automatic] synonym: "involuntary muscle of urinary bladder" EXACT [OBOL:automatic] synonym: "non-striated muscle of bladder" EXACT [OBOL:automatic] synonym: "non-striated muscle of urinary bladder" EXACT [OBOL:automatic] synonym: "smooth muscle of bladder" EXACT [OBOL:automatic] synonym: "smooth muscle of urinary bladder" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of bladder" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of urinary bladder" EXACT [OBOL:automatic] synonym: "urinary bladder involuntary muscle" EXACT [OBOL:automatic] synonym: "urinary bladder muscle" EXACT [MA:0001697] synonym: "urinary bladder non-striated muscle" EXACT [OBOL:automatic] synonym: "urinary bladder smooth muscle tissue" EXACT [OBOL:automatic] xref: BTO:0001849 xref: CALOHA:TS-1087 xref: EMAPA:37791 {source="MA:th"} xref: MA:0001697 is_a: UBERON:0001135 ! smooth muscle tissue intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: BFO:0000050 UBERON:0001255 ! part of urinary bladder relationship: BFO:0000050 UBERON:0001255 ! part of urinary bladder [Term] id: UBERON:0004231 name: anal region smooth muscle namespace: uberon def: "A portion of smooth muscle tissue that is part of an anal region [Automatically generated definition]." [OBOL:automatic] synonym: "anal part of perineum involuntary muscle" EXACT [OBOL:automatic] synonym: "anal part of perineum non-striated muscle" EXACT [OBOL:automatic] synonym: "anal part of perineum smooth muscle" EXACT [OBOL:automatic] synonym: "anal part of perineum smooth muscle tissue" EXACT [OBOL:automatic] synonym: "anal region involuntary muscle" EXACT [OBOL:automatic] synonym: "anal region non-striated muscle" EXACT [OBOL:automatic] synonym: "anal region smooth muscle tissue" EXACT [OBOL:automatic] synonym: "anal triangle involuntary muscle" EXACT [OBOL:automatic] synonym: "anal triangle non-striated muscle" EXACT [OBOL:automatic] synonym: "anal triangle smooth muscle" EXACT [OBOL:automatic] synonym: "anal triangle smooth muscle tissue" EXACT [OBOL:automatic] synonym: "involuntary muscle of anal part of perineum" EXACT [OBOL:automatic] synonym: "involuntary muscle of anal region" EXACT [OBOL:automatic] synonym: "involuntary muscle of anal triangle" EXACT [OBOL:automatic] synonym: "non-striated muscle of anal part of perineum" EXACT [OBOL:automatic] synonym: "non-striated muscle of anal region" EXACT [OBOL:automatic] synonym: "non-striated muscle of anal triangle" EXACT [OBOL:automatic] synonym: "smooth muscle of anal part of perineum" EXACT [OBOL:automatic] synonym: "smooth muscle of anal region" EXACT [OBOL:automatic] synonym: "smooth muscle of anal triangle" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of anal part of perineum" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of anal region" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of anal triangle" EXACT [OBOL:automatic] xref: EMAPA:37394 {source="MA:th"} xref: MA:0001532 is_a: UBERON:0001135 ! smooth muscle tissue intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: BFO:0000050 UBERON:0001353 ! part of anal region relationship: BFO:0000050 UBERON:0001353 ! part of anal region [Term] id: UBERON:0004233 name: lower respiratory tract smooth muscle namespace: uberon def: "A portion of smooth muscle tissue that is part of a lower respiratory tract [Automatically generated definition]." [OBOL:automatic] synonym: "involuntary muscle of lower respiratory tract" EXACT [OBOL:automatic] synonym: "lower respiratory tract involuntary muscle" EXACT [OBOL:automatic] synonym: "lower respiratory tract non-striated muscle" EXACT [OBOL:automatic] synonym: "lower respiratory tract smooth muscle tissue" EXACT [OBOL:automatic] synonym: "non-striated muscle of lower respiratory tract" EXACT [OBOL:automatic] synonym: "smooth muscle of lower respiratory tract" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of lower respiratory tract" EXACT [OBOL:automatic] xref: EMAPA:35520 xref: MA:0002410 is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure is_a: UBERON:0004225 ! respiratory system smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: BFO:0000050 UBERON:0001558 ! part of lower respiratory tract relationship: BFO:0000050 UBERON:0001558 ! part of lower respiratory tract [Term] id: UBERON:0004234 name: iris smooth muscle namespace: uberon def: "A portion of smooth muscle tissue that is part of a iris [Automatically generated definition]." [OBOL:automatic] synonym: "involuntary muscle of iris" EXACT [OBOL:automatic] synonym: "iridial smooth muscle" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "iris involuntary muscle" EXACT [OBOL:automatic] synonym: "iris non-striated muscle" EXACT [OBOL:automatic] synonym: "iris smooth muscle tissue" EXACT [OBOL:automatic] synonym: "non-striated muscle of iris" EXACT [OBOL:automatic] synonym: "smooth muscle of iris" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of iris" EXACT [OBOL:automatic] xref: BTO:0000655 xref: EMAPA:35448 xref: FMA:312338 xref: MA:0001270 is_a: UBERON:0003386 {source="MA"} ! smooth muscle of eye intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: BFO:0000050 UBERON:0001769 ! part of iris relationship: BFO:0000050 UBERON:0001606 ! part of muscle of iris [Term] id: UBERON:0004236 name: arteriole smooth muscle namespace: uberon def: "A portion of smooth muscle tissue that is part of an arteriole [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:36287 xref: FMA:312251 xref: MA:0000706 is_a: UBERON:0004237 ! blood vessel smooth muscle is_a: UBERON:0004695 ! arterial system smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: BFO:0000050 UBERON:0001980 ! part of arteriole relationship: BFO:0000050 UBERON:0001980 ! part of arteriole [Term] id: UBERON:0004237 name: blood vessel smooth muscle namespace: uberon def: "Smooth muscle found within, and composing the majority of the wall of blood vessels." [Wikipedia:Vascular_smooth_muscle] synonym: "blood vessel involuntary muscle" EXACT [OBOL:automatic] synonym: "blood vessel non-striated muscle" EXACT [OBOL:automatic] synonym: "blood vessel smooth muscle tissue" EXACT [OBOL:automatic] synonym: "involuntary muscle of blood vessel" EXACT [OBOL:automatic] synonym: "non-striated muscle of blood vessel" EXACT [OBOL:automatic] synonym: "smooth muscle of blood vessel" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of blood vessel" EXACT [OBOL:automatic] synonym: "vascular smooth muscle" EXACT [ZFA:0005321] synonym: "vascular smooth muscle tissue" EXACT [] xref: BTO:0001431 xref: CALOHA:TS-1107 xref: EMAPA:35177 xref: MA:0000710 xref: MESH:D009131 xref: NCIT:C33853 xref: TAO:0005321 xref: UMLS:C1519956 {source="ncithesaurus:Vascular_Smooth_Muscle_Tissue"} xref: Wikipedia:Vascular_smooth_muscle xref: ZFA:0005321 is_a: UBERON:0001135 ! smooth muscle tissue intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: BFO:0000050 UBERON:0001981 ! part of blood vessel relationship: BFO:0000050 UBERON:0001981 ! part of blood vessel [Term] id: UBERON:0004238 name: spleen smooth muscle namespace: uberon def: "A portion of smooth muscle tissue that is part of a spleen [Automatically generated definition]." [OBOL:automatic] synonym: "involuntary muscle of spleen" EXACT [OBOL:automatic] synonym: "non-striated muscle of spleen" EXACT [OBOL:automatic] synonym: "smooth muscle of spleen" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of spleen" EXACT [OBOL:automatic] synonym: "spleen involuntary muscle" EXACT [OBOL:automatic] synonym: "spleen non-striated muscle" EXACT [OBOL:automatic] synonym: "spleen smooth muscle tissue" EXACT [OBOL:automatic] xref: EMAPA:35807 xref: MA:0000757 is_a: UBERON:0001135 ! smooth muscle tissue intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: BFO:0000050 UBERON:0002106 ! part of spleen relationship: BFO:0000050 UBERON:0002106 ! part of spleen [Term] id: UBERON:0004239 name: small intestine smooth muscle namespace: uberon def: "A portion of smooth muscle tissue that is part of a small intestine [Automatically generated definition]." [OBOL:automatic] synonym: "involuntary muscle of small bowel" EXACT [OBOL:automatic] synonym: "involuntary muscle of small intestine" EXACT [OBOL:automatic] synonym: "non-striated muscle of small bowel" EXACT [OBOL:automatic] synonym: "non-striated muscle of small intestine" EXACT [OBOL:automatic] synonym: "small bowel involuntary muscle" EXACT [OBOL:automatic] synonym: "small bowel non-striated muscle" EXACT [OBOL:automatic] synonym: "small bowel smooth muscle" EXACT [OBOL:automatic] synonym: "small bowel smooth muscle tissue" EXACT [OBOL:automatic] synonym: "small intestine involuntary muscle" EXACT [OBOL:automatic] synonym: "small intestine non-striated muscle" EXACT [OBOL:automatic] synonym: "small intestine smooth muscle tissue" EXACT [OBOL:automatic] synonym: "smooth muscle of small bowel" EXACT [OBOL:automatic] synonym: "smooth muscle of small intestine" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of small bowel" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of small intestine" EXACT [OBOL:automatic] xref: EMAPA:35783 xref: MA:0001559 is_a: UBERON:0004221 ! intestine smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: BFO:0000050 UBERON:0002108 ! part of small intestine relationship: BFO:0000050 UBERON:0001168 ! part of wall of small intestine relationship: RO:0002131 UBERON:0011201 ! overlaps muscle layer of small intestine [Term] id: UBERON:0004240 name: gallbladder smooth muscle namespace: uberon def: "A portion of smooth muscle tissue that is part of a gallbladder [Automatically generated definition]." [OBOL:automatic] synonym: "gall bladder involuntary muscle" EXACT [OBOL:automatic] synonym: "gall bladder non-striated muscle" EXACT [OBOL:automatic] synonym: "gall bladder smooth muscle" EXACT [OBOL:automatic] synonym: "gall bladder smooth muscle tissue" EXACT [OBOL:automatic] synonym: "gallbladder involuntary muscle" EXACT [OBOL:automatic] synonym: "gallbladder non-striated muscle" EXACT [OBOL:automatic] synonym: "gallbladder smooth muscle tissue" EXACT [] synonym: "involuntary muscle of gall bladder" EXACT [OBOL:automatic] synonym: "involuntary muscle of gallbladder" EXACT [OBOL:automatic] synonym: "non-striated muscle of gall bladder" EXACT [OBOL:automatic] synonym: "non-striated muscle of gallbladder" EXACT [OBOL:automatic] synonym: "smooth muscle of gall bladder" EXACT [OBOL:automatic] synonym: "smooth muscle of gallbladder" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of gall bladder" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of gallbladder" EXACT [OBOL:automatic] xref: EMAPA:35373 xref: MA:0001635 xref: NCIT:C49483 xref: UMLS:C1708179 {source="ncithesaurus:Gallbladder_Smooth_Muscle_Tissue"} is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure is_a: UBERON:0001135 ! smooth muscle tissue intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: BFO:0000050 UBERON:0002110 ! part of gallbladder relationship: BFO:0000050 UBERON:0002110 ! part of gallbladder [Term] id: UBERON:0004245 name: oviduct smooth muscle namespace: uberon def: "A portion of smooth muscle tissue that is part of a fallopian tube [Automatically generated definition]." [OBOL:automatic] synonym: "fallopian tube involuntary muscle" EXACT [OBOL:automatic] synonym: "fallopian tube non-striated muscle" EXACT [OBOL:automatic] synonym: "fallopian tube smooth muscle" EXACT [OBOL:automatic] synonym: "fallopian tube smooth muscle tissue" EXACT [OBOL:automatic] synonym: "involuntary muscle of fallopian tube" EXACT [OBOL:automatic] synonym: "non-striated muscle of fallopian tube" EXACT [OBOL:automatic] synonym: "smooth muscle of fallopian tube" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of fallopian tube" EXACT [OBOL:automatic] xref: EMAPA:29046 xref: MA:0001721 is_a: UBERON:0001135 ! smooth muscle tissue is_a: UBERON:0005156 ! reproductive structure intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: BFO:0000050 UBERON:0003889 ! part of fallopian tube relationship: BFO:0000050 UBERON:0003889 ! part of fallopian tube [Term] id: UBERON:0004246 name: outflow tract smooth muscle namespace: uberon def: "A portion of smooth muscle tissue that is part of a outflow tract [Automatically generated definition]." [OBOL:automatic] synonym: "involuntary muscle of outflow tract" EXACT [OBOL:automatic] synonym: "non-striated muscle of outflow tract" EXACT [OBOL:automatic] synonym: "outflow tract involuntary muscle" EXACT [OBOL:automatic] synonym: "outflow tract non-striated muscle" EXACT [OBOL:automatic] synonym: "outflow tract smooth muscle tissue" EXACT [OBOL:automatic] synonym: "smooth muscle of outflow tract" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of outflow tract" EXACT [OBOL:automatic] xref: EMAPA:37708 {source="MA:th"} xref: MA:0000492 is_a: UBERON:0001135 ! smooth muscle tissue intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: BFO:0000050 UBERON:0004145 ! part of outflow tract relationship: BFO:0000050 UBERON:0004145 ! part of outflow tract [Term] id: UBERON:0004247 name: bone of dorsum namespace: uberon def: "A bone that is part of the dorsal region of an animal." [http://orcid.org/0000-0002-6601-2165] xref: EMAPA:37248 {source="MA:th"} xref: MA:0000494 is_a: UBERON:0001474 ! bone element is_a: UBERON:0005174 ! dorsal region element intersection_of: UBERON:0001474 ! bone element intersection_of: BFO:0000050 UBERON:0001137 ! part of dorsum property_value: IAO:0000232 "this class may be obsoleted. See: https://github.com/obophenotype/mouse-anatomy-ontology/issues/93" xsd:string [Term] id: UBERON:0004253 name: skin muscle namespace: uberon def: "Any muscle organ that is part of a skin of body [Automatically generated definition]." [OBOL:automatic] synonym: "integumental system muscle" EXACT [MA:0003139] synonym: "muscle of integumental system" EXACT [EMAPA:18187] synonym: "muscle organ of skin" EXACT [OBOL:automatic] synonym: "skin muscle organ" EXACT [OBOL:automatic] xref: EMAPA:18187 xref: EMAPA:35776 xref: MA:0002710 xref: MA:0003139 is_a: UBERON:0001630 ! muscle organ intersection_of: UBERON:0001630 ! muscle organ intersection_of: BFO:0000050 UBERON:0002416 ! part of integumental system relationship: BFO:0000050 UBERON:0002416 ! part of integumental system relationship: RO:0001025 UBERON:0002097 ! located in skin of body [Term] id: UBERON:0004258 name: back blood vessel namespace: uberon def: "A blood vessel that is part of a back [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of back" EXACT [OBOL:automatic] xref: EMAPA:37243 {source="MA:th"} xref: MA:0000493 is_a: UBERON:0001981 ! blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: BFO:0000050 UBERON:0001137 ! part of dorsum relationship: BFO:0000050 UBERON:0001137 ! part of dorsum [Term] id: UBERON:0004265 name: outflow tract myocardium namespace: uberon def: "A myocardium that is part of a outflow tract [Automatically generated definition]." [OBOL:automatic] synonym: "cardiac muscle of outflow tract" EXACT [OBOL:automatic] synonym: "heart muscle of outflow tract" EXACT [OBOL:automatic] synonym: "heart myocardium of outflow tract" EXACT [OBOL:automatic] synonym: "muscle of heart of outflow tract" EXACT [OBOL:automatic] synonym: "myocardium of outflow tract" EXACT [OBOL:automatic] synonym: "outflow tract cardiac muscle" EXACT [OBOL:automatic] synonym: "outflow tract heart muscle" EXACT [OBOL:automatic] synonym: "outflow tract heart myocardium" EXACT [OBOL:automatic] synonym: "outflow tract muscle of heart" EXACT [OBOL:automatic] xref: EHDAA2:0001358 xref: EMAPA:35623 xref: MA:0000489 xref: VHOG:0000603 is_a: UBERON:0002349 ! myocardium intersection_of: UBERON:0002349 ! myocardium intersection_of: BFO:0000050 UBERON:0004145 ! part of outflow tract relationship: BFO:0000050 UBERON:0004145 ! part of outflow tract [Term] id: UBERON:0004267 name: back connective tissue namespace: uberon def: "A portion of connective tissue that is part of a back [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:37256 {source="MA:th"} xref: MA:0000495 is_a: UBERON:0002384 ! connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: BFO:0000050 UBERON:0001137 ! part of dorsum relationship: BFO:0000050 UBERON:0001137 ! part of dorsum [Term] id: UBERON:0004271 name: outflow tract pericardium namespace: uberon def: "A pericardium that is part of a outflow tract [Automatically generated definition]." [OBOL:automatic] synonym: "pericardium of outflow tract" EXACT [OBOL:automatic] xref: EMAPA:37707 {source="MA:th"} xref: MA:0000491 is_a: UBERON:0002407 ! pericardium is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0002407 ! pericardium intersection_of: BFO:0000050 UBERON:0004145 ! part of outflow tract relationship: BFO:0000050 UBERON:0004145 ! part of outflow tract [Term] id: UBERON:0004277 name: eye muscle namespace: uberon def: "A muscle that is part of the eye region." [OBOL:automatic] xref: AAO:0000156 xref: EMAPA:35335 xref: MA:0000271 is_a: UBERON:0001630 ! muscle organ is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0001630 ! muscle organ intersection_of: BFO:0000050 UBERON:0000019 ! part of camera-type eye relationship: BFO:0000050 UBERON:0000019 {source="MA"} ! part of camera-type eye relationship: RO:0002433 UBERON:0000019 ! contributes to morphology of camera-type eye [Term] id: UBERON:0004288 name: skeleton namespace: uberon def: "Anatomical cluster that consists of all the skeletal elements (eg., bone, cartilage, and teeth) of the body." [VSAO:0000026] synonym: "set of all bones" EXACT [] synonym: "set of bones of body" EXACT [] xref: AEO:0000168 xref: EHDAA2:0001843 xref: EHDAA:5047 xref: EMAPA:17213 xref: FMA:23875 xref: GAID:177 xref: galen:Skeleton xref: MA:0003006 xref: MAT:0000032 xref: MESH:D012863 xref: MIAA:0000032 xref: SCTID:361378004 xref: VSAO:0000026 xref: Wikipedia:Skeleton xref: XAO:0004053 is_a: UBERON:0034925 ! anatomical collection disjoint_from: UBERON:0004770 ! articular system relationship: BFO:0000050 UBERON:0001434 ! part of skeletal system relationship: RO:0002351 UBERON:0004765 ! has member skeletal element [Term] id: UBERON:0004290 name: dermomyotome namespace: uberon def: "The bilaminar epithelium formed from the myotome and dermatome." [AEO:0000214] xref: AAO:0010572 xref: AEO:0000214 xref: EHDAA2:0003259 xref: EMAPA:31109 xref: FMA:295654 xref: NCIT:C34140 xref: TAO:0001513 xref: UMLS:C1511786 {source="ncithesaurus:Dermomyotome"} xref: VHOG:0000676 xref: ZFA:0001513 is_a: UBERON:0000486 {source="AEO"} ! multilaminar epithelium is_a: UBERON:0016888 {source="AEO"} ! transitional anatomical structure relationship: BFO:0000051 CL:0000075 ! has part columnar/cuboidal epithelial cell relationship: RO:0002202 UBERON:0002329 {source="EHDAA2", source="ZFA"} ! develops from somite [Term] id: UBERON:0004291 name: heart rudiment namespace: uberon def: "A cone-like structure that is formed when myocardial progenitor cells of the heart field fuse at the midline. The heart rudiment is the first structure of the heart tube." [GO:0003313] synonym: "heart cone" EXACT [GO:0003313] synonym: "rudimentary heart" EXACT [ZFA:0000115] xref: TAO:0000115 xref: ZFA:0000115 is_a: UBERON:0012275 ! meso-epithelium relationship: RO:0002202 UBERON:0004139 ! develops from cardiogenic plate [Term] id: UBERON:0004292 name: cardiac skeleton namespace: uberon def: "Dense connective tissue that separates the atria from the ventricles and provides physical support for the heart." [GO:0003204, Wikipedia:Cardiac_skeleton] synonym: "cardiac fibrous skeleton" EXACT [EMAPA:36645] synonym: "fibrous skeleton of heart" EXACT [] synonym: "heart fibrous skeleton" EXACT [GO:0003204] synonym: "skeleton of heart" EXACT [FMA:9496] xref: EMAPA:36645 xref: FMA:9496 xref: Wikipedia:Cardiac_skeleton is_a: UBERON:0003837 ! thoracic segment connective tissue is_a: UBERON:0004120 ! mesoderm-derived structure relationship: BFO:0000050 UBERON:0000948 ! part of heart relationship: RO:0002220 UBERON:0002081 ! adjacent to cardiac atrium relationship: RO:0002220 UBERON:0002082 ! adjacent to cardiac ventricle property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/5/50/Gray495.png" xsd:anyURI [Term] id: UBERON:0004297 name: respiratory system blood vessel smooth muscle namespace: uberon def: "A blood vessel smooth muscle that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "smooth muscle tissue of blood vessel of respiratory system" EXACT [OBOL:automatic] xref: EMAPA:37573 {source="MA:th"} xref: MA:0001806 is_a: UBERON:0004225 ! respiratory system smooth muscle is_a: UBERON:0004237 ! blood vessel smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: BFO:0000050 UBERON:0003504 ! part of respiratory system blood vessel relationship: BFO:0000050 UBERON:0003504 ! part of respiratory system blood vessel [Term] id: UBERON:0004340 name: allantois namespace: uberon def: "A membranous sac that develops from the posterior part of the alimentary canal in the embryos of mammals, birds, and reptiles, and it is important in the formation of the umbilical cord and placenta in mammals[VHOG]." [VHOG:0000738, Wikipedia:Allantois] xref: BTO:0000474 xref: EHDAA2:0001504 xref: EMAPA:16107 xref: EMAPA_RETIRED:16084 xref: MESH:D000482 xref: NCIT:C34101 xref: RETIRED_EHDAA2:0000114 xref: SCTID:308825007 xref: UMLS:C0002084 {source="ncithesaurus:Allantois"} xref: VHOG:0000738 xref: Wikipedia:Allantois is_a: UBERON:0005631 ! extraembryonic membrane relationship: RO:0002131 UBERON:0001008 {source="EHDAA2-modified"} ! overlaps renal system relationship: RO:0002160 NCBITaxon:32524 {source="Hymans"} ! only in taxon Amniota relationship: RO:0002202 UBERON:0000162 {source="Hymans"} ! develops from cloaca relationship: RO:0002254 UBERON:0000925 ! has developmental contribution from endoderm relationship: RO:0002254 UBERON:0004872 {source="ISBN:0073040584"} ! has developmental contribution from splanchnic layer of lateral plate mesoderm property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/a/a5/Gray25.png" xsd:anyURI [Term] id: UBERON:0004341 name: primitive streak namespace: uberon def: "The primitive streak is a structure that forms during the early stages of avian, reptilian and mammalian embryonic development[WP]. the midline ridge of the embryonic epiblast that later develops into mesoderm and endoderm[MP]." [MP:0002231, Wikipedia:Primitive_streak] synonym: "primitive streak - blastopore - germ ring" EXACT [VHOG:0001202] xref: EHDAA2:0001525 xref: EHDAA:185 xref: EMAPA:16072 xref: FMA:293110 xref: NCIT:C28402 xref: SCTID:361438007 xref: UMLS:C0033153 {source="ncithesaurus:Primitive_Streak"} xref: VHOG:0001202 xref: Wikipedia:Primitive_streak is_a: UBERON:0000485 {source="EHDAA2"} ! simple columnar epithelium is_a: UBERON:0005291 ! embryonic tissue relationship: RO:0002202 UBERON:0008780 {gci_filler="NCBITaxon:40674", gci_relation="BFO:0000050", source="ISBN:9780878932504"} ! develops from inner cell mass derived epiblast relationship: RO:0002387 UBERON:0000925 ! has potential to develop into endoderm relationship: RO:0002387 UBERON:0000926 ! has potential to develop into mesoderm property_value: x_0.1:depiction "http://upload.wikimedia.org/wikipedia/commons/f/f4/Gray13.png" xsd:anyURI [Term] id: UBERON:0004345 name: trophectoderm namespace: uberon def: "Outermost layer of cells in the blastodermic vesicle, which will develop into the trophoblast layer and then contact the endometrium and take part in establishing the embryo's means of nutrition." [MP:0005028] xref: BTO:0001840 xref: EHDAA2:0002091 xref: EHDAA:56 xref: EMAPA:16046 xref: VHOG:0000979 is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium is_a: UBERON:0005292 ! extraembryonic tissue relationship: BFO:0000050 UBERON:0005631 {source="EHDAA2"} ! part of extraembryonic membrane relationship: BFO:0000051 CL:1000274 ! has part trophectodermal cell relationship: RO:0002202 UBERON:0000085 {source="EHDAA2"} ! develops from morula [Term] id: UBERON:0004348 name: optic eminence namespace: uberon def: "The embryonic structure that gives rise to the corneal ectoderm." [MP:0006305] xref: EHDAA:938 xref: EMAPA:16322 xref: RETIRED_EHDAA2:0001308 xref: VHOG:0001296 is_a: UBERON:0006598 ! presumptive structure relationship: RO:0002387 UBERON:0000964 ! has potential to develop into cornea [Term] id: UBERON:0004356 name: apical ectodermal ridge namespace: uberon def: "Multilayered ectodermal region at the distal tip of a limb or fin bud necessary for the proper development of the underlying mesenchyme[MP,modified]. Along with the zone of polarizing activity, it is a crucial organizing region during limb development[WP]." [MP:0001676, Wikipedia:Apical_ectodermal_ridge] synonym: "apical epidermal ridge" EXACT [XAO:0004121] xref: AAO: