format-version: 1.2 data-version: releases/2025-03-18 subsetdef: 1_STAR "" subsetdef: 2_STAR "" subsetdef: 3_STAR "" subsetdef: abnormal_slim "" subsetdef: absent_slim "" subsetdef: added_for_HCA "" subsetdef: AISM:0000171 "" subsetdef: attribute_slim "" subsetdef: blood_and_immune_upper_slim "" subsetdef: cell_quality "" subsetdef: cellxgene_subset "" subsetdef: common_anatomy "" subsetdef: cumbo "" subsetdef: developmental_classification "" subsetdef: disposition_slim "" subsetdef: early_development "" subsetdef: efo_slim "" subsetdef: emapa_ehdaa2 "" subsetdef: eye_upper_slim "" subsetdef: functional_classification "" subsetdef: general_cell_types_upper_slim "" subsetdef: gocheck_do_not_annotate "" subsetdef: gocheck_do_not_manually_annotate "" subsetdef: goslim_agr "" subsetdef: goslim_candida "" subsetdef: goslim_chembl "" subsetdef: goslim_drosophila "" subsetdef: goslim_flybase_ribbon "" subsetdef: goslim_generic "" subsetdef: goslim_metagenomics "" subsetdef: goslim_mouse "" subsetdef: goslim_pir "" subsetdef: goslim_plant "" subsetdef: goslim_pombe "" subsetdef: goslim_prokaryote "" subsetdef: goslim_synapse "" subsetdef: goslim_yeast "" subsetdef: grouping_class "" subsetdef: homology_grouping "" subsetdef: hpo_slim "" subsetdef: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension "" subsetdef: http://purl.obolibrary.org/obo/valid_for_go_gp2term "" subsetdef: http://purl.obolibrary.org/obo/valid_for_go_ontology "" subsetdef: http://purl.obolibrary.org/obo/valid_for_gocam "" subsetdef: human_reference_atlas "" subsetdef: human_subset "" subsetdef: inconsistent_with_fma "" subsetdef: kidney_upper_slim "" subsetdef: location_grouping "" subsetdef: major_organ "" subsetdef: mouse_subset "" subsetdef: mpath_slim "" subsetdef: non_informative "" subsetdef: organ_slim "" subsetdef: pheno_slim "" subsetdef: phenotype_rcn "" subsetdef: relational_slim "" subsetdef: ro-eco "" subsetdef: RO:0002259 "" subsetdef: scalar_slim "" subsetdef: uberon_slim "" subsetdef: ubprop:upper_level "" subsetdef: unverified_taxonomic_grouping "" subsetdef: upper_level "" subsetdef: value_slim "" subsetdef: vertebrate_core "" synonymtypedef: blast_name "" synonymtypedef: DEPRECATED "" synonymtypedef: equivalent_name "" synonymtypedef: genbank_common_name "" synonymtypedef: Gene-based "" synonymtypedef: human "" synonymtypedef: HUMAN_PREFERRED "" synonymtypedef: in_part "" synonymtypedef: INCONSISTENT "" synonymtypedef: INN "" synonymtypedef: IUPAC_NAME "" synonymtypedef: OMO:0003000 "" synonymtypedef: OMO:0003002 "" synonymtypedef: OMO:0003003 "" synonymtypedef: OMO:0003004 "" synonymtypedef: OMO:0003011 "" synonymtypedef: PENDING_REVIEW "" synonymtypedef: PRO-short-label "" synonymtypedef: scientific_name "" synonymtypedef: SENSU "" synonymtypedef: syngo_official_label "" synonymtypedef: synonym "" synonymtypedef: systematic_synonym "" synonymtypedef: vertebrate "" idspace: cito http://purl.org/spar/cito/ idspace: doap http://usefulinc.com/ns/doap# idspace: obo1 http://www.geneontology.org/formats/oboInOwl#http://purl.obolibrary.org/obo/ idspace: oboI http://www.geneontology.org/formats/oboInOwl# idspace: oboInOwl ttp://www.geneontology.org/formats/oboInOwl# idspace: protege http://protege.stanford.edu/plugins/owl/protege# idspace: skos http://www.w3.org/2004/02/skos/core# idspace: sssom https://w3id.org/sssom/ idspace: swrl http://www.w3.org/2003/11/swrl# idspace: swrla http://swrl.stanford.edu/ontologies/3.3/swrla.owl# idspace: swrlb http://www.w3.org/2003/11/swrlb# idspace: term http://purl.org/dc/terms/ idspace: terms http://www.geneontology.org/formats/oboInOwl#http://purl.org/dc/terms/ idspace: vocab https://w3id.org/semapv/vocab/ idspace: x_0.1 http://xmlns.com/foaf/0.1/ idspace: x_1.1 http://purl.org/dc/elements/1.1/ ontology: aism property_value: dc-description "The ontology for the Anatomy of the Insect SkeletoMuscular system (AISM) contains terms used to describe the cuticle - as a single anatomical structure - and the skeletal muscle system, to be used in insect biodiversity research." xsd:string property_value: dc-title "Ontology for the Anatomy of the Insect SkeletoMuscular system" xsd:string property_value: dcterms-license https://creativecommons.org/licenses/by/4.0/ property_value: has_ontology_root_term "http://purl.obolibrary.org/obo/AISM_0000174" xsd:string property_value: has_ontology_root_term "http://purl.obolibrary.org/obo/PATO_0000001" xsd:string property_value: has_ontology_root_term "http://purl.obolibrary.org/obo/UBERON_0001062" xsd:string property_value: owl:versionInfo "2025-03-18" xsd:string property_value: x_1.1:contributor "Giulio Montanaro (gmontanaro) https://orcid.org/0000-0003-0836-1364" xsd:string property_value: x_1.1:contributor "István Mikó (imiko) https://orcid.org/0000-0003-2938-9075" xsd:string property_value: x_1.1:contributor "Jennifer C. Girón (jgiron) https://orcid.org/0000-0002-0851-6883" xsd:string property_value: x_1.1:contributor "Luis A. González Montaña (lagonzalezmo) https://orcid.org/0000-0002-9136-9932" xsd:string property_value: x_1.1:contributor "Sergei Tarasov (starasov) https://orcid.org/0000-0001-5237-2330" xsd:string [Term] id: AISM:0000000 name: cuticular internal depression def: "The projection of the inner surface of the cuticle." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-05-19"} is_a: AISM:0000174 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect region of cuticle relationship: has_characteristic PATO:0001857 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! concave relationship: part_of BSPO:0000061 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! proximal side [Term] id: AISM:0000001 name: resilin {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} def: "Resilin is an elastomeric protein found in many insects and other arthropods. It provides soft rubber-elasticity to mechanically active organs and tissue.\nhttps://en.wikipedia.org/wiki/Resilin" [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} is_a: PR:000000001 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} ! protein property_value: curator_notes "This is a generalized term to refer to this protein as the only option available now is pro-resilin (fruit fly) [http://purl.obolibrary.org/obo/PR_Q9V7U0]" xsd:string {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} [Term] id: AISM:0000002 name: insect articulation def: "The region of cuticle that is composed two articular surfaces that are adjacent to each other." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-10-27"} is_a: AISM:0000174 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect region of cuticle property_value: curator_notes "Articulations are 'anatomical clusters', collections of not direclty connected (continuous) sclerite surfaces that are adjacent to another sclerite. The cranio-mandibular articulation is the articular surface of the cranium and the adjacent articular surface of the mandible. The articular surfaces are sometimes located on the same sclerite." xsd:string {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} [Term] id: AISM:0000003 name: insect sclerite {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Sclerite: distinctly sclerotized region of the integument, with thick layer of exocuticle.\"", IAO:0000232="Modified 2023-01-09: specifying insect sclerite.\njgiron https://orcid.org/0000-0002-0851-6883"} def: "The region of the insect cuticle that is less flexible than the neighboring conjunctiva(e) (conjunctiva(e) that the sclerite is continuous with." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-10-27"} xref: http://flybase.org/cgi-bin/fbcvq.html?query=FBbt\:00004475 "sclerite" xref: http://purl.obolibrary.org/obo/HAO_0000909 "sclerite" {def="The area of the cuticle that is less flexible than adjacent conjunctivae."} xref: http://purl.obolibrary.org/obo/UBERON_6004475 "insect sclerite" is_a: AISM:0000174 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect region of cuticle property_value: IAO:0000118 "esclerito" xsd:string {creation_date="2023-01-09"} [Term] id: AISM:0000004 name: conjunctiva def: "The region of the insect cuticle that is more flexible than the neighboring sclerite(s) [sclerite(s) that the conjunctiva is continuous with]." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-10-27"} synonym: "membrane" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Membrane: very flexible, unsclerotized area of the integument.\""} xref: http://purl.obolibrary.org/obo/HAO_0000221 "conjunctiva" {def="The area of the cuticle that is more flexible than adjacent sclerites."} is_a: AISM:0000174 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect region of cuticle relationship: continuous_with AISM:0000003 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite property_value: curator_notes "Conjunctivae are more flexible and usually less thick than sclerties of the cuticle allowing the sclerites to move relative to each other.\nMicro-CT based methods cannot be used to accurately differentiate slcerites from conjunctiuvae. CLSM (the excitation wavelengths of sclerites and conjunctivae are different in response of 488 nm emission vawelength), histological sections or simple dissections need to be applied to define relative flexibility of the insect cuticle.\n\nIf a conjunctiva entirelly encircles a sclerite, then the 'encircles' and 'encircled by' object properties are used to link the sclerite and the conjunctiva even in cases in which the encircled sclerites or conjunctivae are part of an evagination allowing to model spatial relationship between appendage segments: the pedicel is encircled by the scapal-pedicellar conjunctiva, which is encircled by the scape or the the coxa encircles the coxo-femoral conjunctiuva that encircels the femur." xsd:string {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} [Term] id: AISM:0000005 name: cuticular depression def: "The region of the cuticle that corresponds to a concave surface." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-10-27"} is_a: BFO:0000004 ! independent continuant relationship: has_characteristic PATO:0001857 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! concave relationship: in_distal_side_of AISM:0000174 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect region of cuticle property_value: curator_notes "External cuticular depression. The surface of the cuticle in insects is the entire surface of an organism, and it is composed of flat, concave and convex regions. Concavities sometimes correspons with invaginations of the cuticle and the underlaying sinlge layer epidermis, somtimes correspond to a decreased cuticular thickness." xsd:string {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} [Term] id: AISM:0000006 name: cuticular invagination def: "The region of cuticle that corresponds with an invagination of the single layer epidermis (epidermal fold). The cuticular invagination sometimes corresponds to a cuticular depression (concavity on the surface of the cuticle)." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-10-27"} is_a: AISM:0000174 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect region of cuticle relationship: RO:0002008 AISM:0000000 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coincident with cuticular internal depression relationship: RO:0002008 AISM:0000005 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coincident with cuticular depression [Term] id: AISM:0000007 name: elastic cuticle {creation_date="2020-10-27"} def: "The region of cuticle with higher content of resilin." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect region of cuticle is_a: PR:000050567 ! protein-containing material entity relationship: composed_primarily_of AISM:0000001 {IAO:0000232="Modified 2024-02-14: updated to 'composed primarily of' and linked to resilin\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! resilin [Term] id: AISM:0000008 name: cuticular protrusion def: "The region of the cuticle that corresponds to a convex surface." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-10-27"} is_a: AISM:0000174 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect region of cuticle relationship: has_characteristic PATO:0001355 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! convex relationship: part_of BSPO:0000062 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! distal side property_value: curator_notes "The surface of the cuticle in insects is the entire surface of an organism, and it is composed of flat, concave and convex regions. Convexities sometimes correspons with evaginations of the cuticle and the underlaying sinlge layer epidermis and sometimes correspond to an increased cuticular thickness.\"" xsd:string {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} [Term] id: AISM:0000009 name: cuticular fossa {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} def: "The cuticular depression that is adjacent to a cuticular condyle." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} is_a: AISM:0000005 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} ! cuticular depression relationship: adjacent_to AISM:0000010 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} ! cuticular condyle [Term] id: AISM:0000010 name: cuticular condyle {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} def: "The cuticular protrusion that is part of an insect sclerite and adjacent to an articular surface." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} is_a: AISM:0000008 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} ! cuticular protrusion relationship: adjacent_to AISM:0000167 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} ! articular surface relationship: part_of AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} ! insect sclerite [Term] id: AISM:0000013 name: evaginated {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-10-27"} def: "A part or structure that is produced by evagination." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"} is_a: PATO:0001355 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! convex [Term] id: AISM:0000014 name: insect cranio-mandibular articulation {IAO:0000232="Modified 2023-02-05: specified insect.\njgiron https://orcid.org/0000-0002-0851-6883"} def: "The articulation between the mandible and the cranium." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-10-27"} is_a: AISM:0000002 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect articulation [Term] id: AISM:0000015 name: cranio-cardinal articulation def: "The articulation between the cardo and the cranium." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-10-27"} is_a: AISM:0000002 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect articulation [Term] id: AISM:0000016 name: cranio-antennal articulation def: "The articulation between the scapus and the cranium." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-10-27"} is_a: AISM:0000002 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect articulation [Term] id: AISM:0000017 name: insect head-cervical articulation {IAO:0000232="Modified 2023-02-05: specified insect.\njgiron https://orcid.org/0000-0002-0851-6883"} def: "The articulation between the head and the neck." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-10-27"} is_a: AISM:0000002 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect articulation [Term] id: AISM:0000018 name: cardo {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043\n\n\"Cardo: basal element of maxilla, articulating with head capsule; usually moved by one cranial muscle and one tentorial muscle.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The sclerite of the insect maxilla that is attached to the head capsule by the oral foraminal conjunctiva and to the cuticle of stipes by the stipito-cardinal conjunctiva." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000003 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite relationship: adjacent_to AISM:0000019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! head capsule relationship: adjacent_to AISM:0000111 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! stipes relationship: continuous_with AISM:0000099 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! oral foraminal conjunctiva relationship: continuous_with AISM:0000110 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cardo-stipital conjunctiva relationship: part_of AISM:0000044 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect maxilla property_value: IAO:0000589 "cuticle of cardo" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000019 name: head capsule {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"The head capsule is almost always a rigid, well sclerotized structural unit, equipped with a defined set of appendages. It is reinforced by strengthening ridges and the endoskeletal tentorium\""} def: "The sclerite of the insect head that is attached to the neck membrane and the oral foraminal conjunctiva, bears the eye cuticle and surrounds the brain" [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} synonym: "cephalic capsule" EXACT [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} synonym: "insect cranium" EXACT [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000003 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite relationship: AISM:0000078 AISM:0000099 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircles oral foraminal conjunctiva relationship: continuous_with AISM:0000098 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! neck membrane relationship: has_part AISM:0000088 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! eye cuticle relationship: part_of AISM:0000107 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect head relationship: surrounds UBERON:0000955 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! brain [Term] id: AISM:0000020 name: dorsal second axillary sclerite def: "The axillary sclerite that is on the dorsal region of the basal wing conjunctiva and lateral to the first axillary sclerite." [] {creation_date="2021-04-10", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004161 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! axillary sclerite relationship: AISM:0000011 AISM:0000022 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! lateral_to first axillary sclerite [Term] id: AISM:0000021 name: abdominal tergite I def: "Is the abdominal tergite of the preabdomen that is attached to the posterior margin of the tergum by the metanoto-abdominal tergite I conjunctiva." [] {IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0004057 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite relationship: anteriorly_connected_to AISM:0004082 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metanoto-abdominal tergite I conjunctiva relationship: part_of AISM:0004055 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! preabdomen [Term] id: AISM:0000022 name: first axillary sclerite def: "The axillary sclerite that is part of the dorsal region of the basal wing conjunctiva and is anterior to the third axillary sclerite." [] {creation_date="2021-04-10", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004161 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! axillary sclerite relationship: anterior_to AISM:0004223 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! third axillary sclerite [Term] id: AISM:0000023 name: galea {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Galea: outer endite lobe of maxilla, usually semimembranous and equipped with sensilla (mainly chemoreceptors).\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the appendage of the insect maxilla that is attached to the stipes by the stipito-galeal conjunctiva." [] {term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000029 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect appendage relationship: adjacent_to AISM:0000111 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! stipes relationship: continuous_with AISM:0004011 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! stipito-galeal conjunctiva relationship: part_of AISM:0000044 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect maxilla property_value: IAO:0000589 "cuticle of galea" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000024 name: labial palpus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Labial palp: tactile appendage of the labium.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the paired appendage of the labium that is attached to the palpiger by the palpigero-palpal conjunctiva." [] {term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000029 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect appendage relationship: adjacent_to AISM:0004006 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! palpiger relationship: AISM:0000079 AISM:0004017 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by palpigero-palpal conjunctiva relationship: has_characteristic PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired relationship: part_of AISM:0000087 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labium property_value: IAO:0000589 "cuticle of labial palpus" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000026 name: lacinia {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Lacinia: inner endite lobe of maxilla, usually firmly connected or fused with stipes; usually sclerotized, with mesally curved apex and articulated spines arranged along mesal edge.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the appendage of the insect maxilla that is attached to the cuticle of stipes by the stipito-lacinial conjunctiva." [] {term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000029 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect appendage relationship: adjacent_to AISM:0000111 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! stipes relationship: continuous_with AISM:0004009 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! stipito-lacinial conjunctiva relationship: part_of AISM:0000044 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect maxilla property_value: IAO:0000589 "cuticle of lacinia" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000027 name: cuticular evagination def: "The region of cuticle that corresponds with an evagination of the cuticle and the single layer epidermis (epidermal fold). The cuticular evagination usually corresponds to a cuticular protrusion (convexity on the surface of the cuticle)." [] {creation_date="2020-11-11", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000008 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular protrusion intersection_of: AISM:0000008 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! cuticular protrusion intersection_of: has_characteristic AISM:0000013 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! evaginated intersection_of: RO:0002008 UBERON:0005157 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! coincident with epithelial fold relationship: has_characteristic AISM:0000013 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! evaginated relationship: RO:0002008 UBERON:0005157 {creation_date="imiko https://orcid.org/0000-0003-2938-9075"} ! coincident with epithelial fold [Term] id: AISM:0000028 name: solid cuticular protrusion {creation_date="2020-11-11"} def: "The cuticular protrusion that does not correspond to an evagination." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"} is_a: AISM:0000008 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular protrusion [Term] id: AISM:0000029 name: insect appendage {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"any part, piece, or organ attached by a joint to the body or to any other main structure\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The evagination of the cuticle that is musculated (connected to the body via muscles)." [] {creation_date="2020-11-11", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000128 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! multicellular cuticular evagination intersection_of: AISM:0000128 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! multicellular cuticular evagination intersection_of: continuous_with UBERON:0014895 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! somatic muscle relationship: continuous_with UBERON:0014895 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! somatic muscle property_value: IAO:0000589 "cuticle of insect appendage" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000031 name: insect leg {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the paired appendage of the insect thorax that is composed of coxa, trochanter, femur, tibia, tarsus, and pretarsus." [] {term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0000029 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect appendage relationship: has_characteristic PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired relationship: has_part AISM:0000047 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pretarsus relationship: has_part AISM:0000075 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tibia relationship: has_part AISM:0000076 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! femur relationship: has_part AISM:0000077 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! coxa relationship: has_part AISM:0004168 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! trochanter relationship: has_part AISM:0004169 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tarsus relationship: part_of AISM:0000108 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect thorax property_value: IAO:0000589 "cuticle of insect leg" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000032 name: antenna {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043\n\n\"Antenna: head appendage of segment 2, innervated by deutocerebrum; in Insecta composed of scapus, pedicellus and flagellum; primarily multisegmented and filiform.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the appendage of the head capsule that is connected by the antenniferal-scapal conjunctiva to the cuticle of the scapus, which is connected by the scapal-pedicellar conjunctiva to the cuticle of the pedicellus; the cuticle of the pedicellus is connected by the pedicellar-first flagellomeral conjunctiva to the cuticle of the first flagellomere; the cuticle of the first flagellomere is connected by interflagellomeral conjunctiva to the next cuticle of flagellomere. Further cuticle of flagellomeres are connected to each other by interflagellomeral conjunctiva." [] {term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000029 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect appendage relationship: AISM:0000079 AISM:0004007 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by antenniferal-scapal conjunctiva relationship: has_characteristic PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired relationship: has_part AISM:0000113 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! scapus relationship: has_part AISM:0000114 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! scapal-pedicellar conjunctiva relationship: has_part AISM:0000115 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pedicellus relationship: has_part AISM:0000117 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! flagellomere 1 relationship: has_part AISM:0000118 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pedicellar-first flagellomeral conjunctiva relationship: has_part AISM:0004008 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! interflagellomeral conjunctiva relationship: part_of UBERON:6003007 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect adult head property_value: IAO:0000589 "cuticle of antenna" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000033 name: insect wing {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"in adult insects or subimago of Ephemeroptera, paired mambranous appendages, supported by veins, located on the mesothorax or metathorax, functioning in flight\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the flat, paired appendage on the dorso-lateral region of the pterothorax." [] {term:modified="2021-12-08", creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000029 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect appendage relationship: has_characteristic PATO:0000407 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! flat relationship: has_characteristic PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired property_value: IAO:0000589 "cuticle of insect wing" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000034 name: fore leg {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the paired appendage of the prothorax that is anterior to the cuticle of a mid leg and composed of cuticle of procoxa, cuticle of protrochanter, cuticle of profemur, cuticle of protibia, cuticle of protarsus, and cuticle of propretarsus." [] {creation_date="2021-04-03", term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000031 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect leg relationship: anterior_to AISM:0000035 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mid leg relationship: has_part AISM:0000066 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! procoxa relationship: has_part AISM:0000067 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! protibia relationship: has_part AISM:0000070 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! profemur relationship: has_part AISM:0004171 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! protrochanter relationship: has_part AISM:0004190 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! protarsus relationship: has_part AISM:0004194 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! propretarsus relationship: part_of AISM:0004125 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prothorax property_value: IAO:0000589 "cuticle of fore leg" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000035 name: mid leg {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the paired appendage of the mesothorax that is posterior to the cuticle of a fore leg, anterior to the cuticle of a hind leg, and composed of cuticle of mesocoxa, cuticle of mesotrochanter, cuticle of mesofemur, cuticle of mesotibia, cuticle of mesotarsus, and cuticle of mesopretarsus." [] {creation_date="2021-04-03", term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000031 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect leg relationship: anterior_to AISM:0000036 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! hind leg relationship: has_part AISM:0000064 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesocoxa relationship: has_part AISM:0000068 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesotibia relationship: has_part AISM:0000071 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesofemur relationship: has_part AISM:0004172 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesotrochanter relationship: has_part AISM:0004189 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesotarsus relationship: has_part AISM:0004195 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesopretarsus relationship: part_of AISM:0004126 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesothorax relationship: posterior_to AISM:0000034 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! fore leg property_value: IAO:0000589 "cuticle of mid leg" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000036 name: hind leg {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the paired appendage of the metathorax that is posterior to the cuticle of a mid leg and composed of cuticle of metacoxa, cuticle of metatrochanter, cuticle of metafemur, cuticle of metatibia, cuticle of metatarsus, and cuticle of metapretarsus." [] {creation_date="2021-04-03", term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000031 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect leg relationship: has_part AISM:0000065 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metacoxa relationship: has_part AISM:0000069 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metatibia relationship: has_part AISM:0000072 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metafemur relationship: has_part AISM:0004173 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metatrochanter relationship: has_part AISM:0004188 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metatarsus relationship: has_part AISM:0004196 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metapretarsus relationship: part_of AISM:0004127 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metathorax relationship: posterior_to AISM:0000035 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mid leg property_value: IAO:0000589 "cuticle of hind leg" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000037 name: fore wing {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the paired insect wing that is continuous with the mesonotum." [] {term:modified="2021-12-08", creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000033 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect wing relationship: continuous_with AISM:0000052 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! mesonotum property_value: IAO:0000589 "cuticle of fore wing" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000038 name: hind wing {IAO:0000232="2021-12-08Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the paired insect wing that is continuous with the metanotum." [] {term:modified="2021-12-08", creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000033 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect wing relationship: continuous_with AISM:0000169 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! metanotum property_value: IAO:0000589 "cuticle of hind wing" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000039 name: cuticular seta {creation_date="2020-11-11", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Seta (=macrotrichium): articulated hair with socket, formed by trichogen cell.\"", term:modified="2021-12-10"} def: "The unicellular cuticular evagination that constitutes a sclerite with its base surrounded by socket membrane." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000003 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite is_a: AISM:0000127 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! unicellular cuticular evagination relationship: AISM:0000079 AISM:0000102 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by ring conjunctiva [Term] id: AISM:0000040 name: cuticular spur {source="https://doi.org/10.1016/0020-7322(79)90013-8", AISM:0000171="Richards AG, Richards PA (1979) The cuticular protuberances of insects. International Journal of Insect Morphology and Embryology 8: 143–157. \n\n\"Multicellular protuberances without differentiation of specialized cells\"", term:modified="2021-12-10"} def: "The multicellular evagination of the cuticle that corresponds to an epithelial fold, composed of some sclerite that is encricled by a conjunctiva (moveable)." [] {creation_date="2020-11-11", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000003 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite is_a: AISM:0000128 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! multicellular cuticular evagination relationship: AISM:0000079 AISM:0000102 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by ring conjunctiva property_value: curator_notes "The difference between an appendage and a spur is the lack of muscles attached to the spur, otherwise, the mandible would be also a spur. Spines are multicellular evaginations that are not encircled by conjunctivae. Moveable beetle horns are spurs while not moveable beetle horns are spines." xsd:string {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-11-11"} [Term] id: AISM:0000041 name: cuticular scale {term:modified="2021-12-10"} def: "The seta that is flat." [] {creation_date="2020-11-11", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000039 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular seta relationship: has_characteristic PATO:0002254 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! flattened [Term] id: AISM:0000042 name: labrum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Labrum: unpaired upper lip, connected with distal edge of clypeus.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the mouthpart and appendage that is attached to the clypeus by the clypeo-labral conjunctiva and to the proximal margin of the epipharynx." [] {term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000165 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! mouthpart relationship: adjacent_to AISM:0004019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! clypeus relationship: continuous_with AISM:0004018 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! clypeo-labral conjunctiva property_value: IAO:0000589 "cuticle of labrum" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000043 name: insect mandible {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043\n\n\"The mandibles are the paired appendages of the 4th head segment and receive their innervation from the anterior part of the suboesophageal ganglion [...] They are primarily a compact, undivided and strongly sclerotized element without appendages.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the mouthpart and sclerite between the cuticle of the labrum and the cuticle of the insect maxilla that is attached to the head capsule by the oral foraminal conjunctiva and the cranio-mandibular muscle." [] {term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000003 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite is_a: AISM:0000165 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! mouthpart relationship: adjacent_to AISM:0000019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! head capsule relationship: anterior_to AISM:0000044 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect maxilla relationship: continuous_with AISM:0000082 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cranio-mandibular muscle relationship: continuous_with AISM:0000099 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! oral foraminal conjunctiva relationship: has_characteristic PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired relationship: posterior_to AISM:0000042 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labrum property_value: IAO:0000589 "cuticle of insect mandible" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000044 name: insect maxilla {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043\n\n\"Maxilla: head appendage of segment 5, innervated by maxillary nerve originating from intermediate part of suboesophageal complex; primarily composed of cardo, stipes, endite lobes (lacinia, galea) and maxillary palp.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the mouthpart appendage of the head capsule, between the cuticle of the insect mandible and the cuticle of the labium, composed of cuticle of cardo, which is attached to the cuticle of stipes by the cardo-stipital conjunctiva; the cuticle of stipes, which is attached to the cuticle of galea by the stipito-galeal conjunctiva, to the cuticle of lacinia by the stipito-lacinial conjunctiva, and to the cuticle of palpifer by the stipito-palpiferal conjunctiva; the cuticle of palpifer is attached to the cuticle of maxillary palpus by the palpifero-palpal conjunctiva." [] {term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000165 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! mouthpart relationship: adjacent_to AISM:0000019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! head capsule relationship: anterior_to AISM:0000087 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labium relationship: has_characteristic PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired relationship: has_part AISM:0000018 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cardo relationship: has_part AISM:0000023 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! galea relationship: has_part AISM:0000026 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! lacinia relationship: has_part AISM:0000051 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! maxillary palpus relationship: has_part AISM:0000110 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cardo-stipital conjunctiva relationship: has_part AISM:0000111 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! stipes relationship: has_part AISM:0004001 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! palpifer relationship: has_part AISM:0004009 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! stipito-lacinial conjunctiva relationship: has_part AISM:0004010 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! stipito-palpiferal conjunctiva relationship: has_part AISM:0004011 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! stipito-galeal conjunctiva relationship: has_part AISM:0004012 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! palpifero-palpal conjunctiva relationship: posterior_to AISM:0000043 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect mandible property_value: IAO:0000589 "cuticle of insect maxilla" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000045 name: mesothoracic-metathoracic conjunctiva def: "The conjunctiva of the insect thorax that connects the mesothorax and the metathorax." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: continuous_with AISM:0004126 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! mesothorax relationship: continuous_with AISM:0004127 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! metathorax relationship: part_of AISM:0000108 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect thorax [Term] id: AISM:0000046 name: prothoracic-mesothoracic conjunctiva def: "The conjunctiva of the insect thorax joining the prothorax and the mesothorax." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2020-03-18"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: continuous_with AISM:0004125 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prothorax relationship: continuous_with AISM:0004126 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesothorax relationship: part_of AISM:0000108 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect thorax [Term] id: AISM:0000047 name: pretarsus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Pretarsus: apical element of leg bearing ungues; distinct and cylindrical in entognathous hexapods, strongly reduced in Insecta.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the appendage of the insect leg that is attached to the cuticle of tarsus by the tarso-pretarsal conjunctiva." [] {term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0000029 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect appendage relationship: continuous_with AISM:0004187 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tarso-pretarsal conjunctiva relationship: part_of AISM:0000031 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect leg property_value: IAO:0000589 "cuticle of pretarsus" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000048 name: ligula {AISM:0000171="Snodgrass RE (1993) Principles of Insect Morphology. Cornell University Press, 768 pp.\n\nhttps://www.jstor.org/stable/10.7591/j.ctv1nhm1j\n\n\"Ligula - The terminal lobes of the labium collectively, or a terminal part of the labium formed by the union of the lobes.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the appendage of the cuticle of labium composed of the cuticle of glossa and cuticle of paraglossa jointly." [] {term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000029 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect appendage relationship: has_part AISM:0000049 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! glossa relationship: has_part AISM:0000050 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! paraglossa relationship: part_of AISM:0000087 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! labium property_value: IAO:0000589 "cuticle of ligula" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000049 name: glossa {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Glossa: paired inner endite lobes of the prementum.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the appendage of the labium, and part of the ligula, that is attached to the prementum by the premental-glossal conjunctiva." [] {term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000029 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect appendage relationship: adjacent_to AISM:0000057 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prementum relationship: continuous_with AISM:0004016 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! premental-glossal conjunctiva relationship: part_of AISM:0000048 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! ligula property_value: IAO:0000589 "cuticle of glossa" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000050 name: paraglossa {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Paraglossa: paired outer endite lobes of the prementum (labium).\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the paired appendage of the labium, and part of the ligula, that is attached to the cuticle of prementum by the premental-paraglossal conjunctiva." [] {term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000029 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect appendage relationship: adjacent_to AISM:0000057 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prementum relationship: continuous_with AISM:0004015 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! premental-paraglossal conjunctiva relationship: part_of AISM:0000048 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! ligula property_value: IAO:0000589 "cuticle of paraglossa" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000051 name: maxillary palpus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043\n\n\"Palp: tactile appendage of maxilla\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the appendage of the insect maxilla that is attached to the cuticle of palpifer by the palpifero-palpal conjunctiva." [] {term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000029 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect appendage relationship: adjacent_to AISM:0000019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! head capsule relationship: adjacent_to AISM:0004001 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! palpifer relationship: AISM:0000079 AISM:0004012 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by palpifero-palpal conjunctiva relationship: has_characteristic PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired relationship: has_part AISM:0002036 {creation_date="2023-04-13"} ! maxillary palpomere relationship: part_of AISM:0000044 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect maxilla property_value: IAO:0000589 "cuticle of maxillary palpus" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000052 name: mesonotum def: "The notum or sclerite on the dorsal region of the mesothorax that is posterior to the pronotum, connected via the mesonoto-mesopleural conjuntiva to the dorsal margin of the mesopleuron, that is not adjacent to the mesocoxa, but attached to it by the mesocoxal muscle." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000003 {x_1.1:contributor="jcgiron"} ! insect sclerite is_a: AISM:0004128 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! notum is_a: UBERON:0000061 ! anatomical structure relationship: attaches_to AISM:0000085 {x_1.1:contributor="jcgiron"} ! mesocoxal muscle relationship: continuous_with AISM:0004219 {x_1.1:contributor="jcgiron"} ! mesonoto-mesopleural conjuntiva relationship: posterior_to AISM:0000059 {x_1.1:contributor="jcgiron"} ! pronotum [Term] id: AISM:0000053 name: mesopectus {creation_date="2020-11-11"} def: "The sclerite that is continuous with the basal mesocoxal conjunctiva and the basal wing conjunctiva and contains the mesofurca." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"} is_a: AISM:0000003 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite relationship: continuous_with AISM:0000103 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! basal mesocoxal conjunctiva relationship: continuous_with AISM:0004203 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! basal wing conjunctiva relationship: has_part AISM:0000141 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! mesofurca [Term] id: AISM:0000054 name: mesotrochantin {creation_date="2020-11-11"} def: "The trochantin that is located on the ventro-lateral region of the mesothorax and is attached to a mesocoxa and surrounded by the basal mesocoxal conjunctiva." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004135 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! trochantin relationship: adjacent_to AISM:0000064 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesocoxa relationship: AISM:0000079 AISM:0000103 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by basal mesocoxal conjunctiva [Term] id: AISM:0000055 name: protrochantin {creation_date="2020-11-11"} def: "The trochantin that is located on the ventro-lateral region of the prothorax and is attached to a procoxa and surrounded by the basal procoxal conjunctiva." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004135 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! trochantin relationship: adjacent_to AISM:0000066 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! procoxa relationship: AISM:0000079 AISM:0000106 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by basal procoxal conjunctiva [Term] id: AISM:0000056 name: metatrochantin {creation_date="2020-11-11"} def: "The trochantin that is located on the ventro-lateral region of the metathorax and is attached to a metacoxa and surrounded by the basal metacoxal conjunctiva." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004135 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! trochantin relationship: adjacent_to AISM:0000065 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metacoxa relationship: AISM:0000079 AISM:0000104 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by basal metacoxal conjunctiva [Term] id: AISM:0000057 name: prementum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Prementum: distal main element of labium, bearing the endite lobes (glossa and paraglossa) and the labial palp.\""} def: "The sclerite of the labium that is connected to the mentum by the mental-premental conjunctiva, to the palpiger by the premental-palpigeral conjunctiva, to the paraglossa by the premental-paraglossal conjunctiva, and to the glossa by the premental-glossal conjunctiva." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000003 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite relationship: adjacent_to AISM:0000049 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! glossa relationship: adjacent_to AISM:0000050 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! paraglossa relationship: adjacent_to AISM:0004004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect mentum relationship: adjacent_to AISM:0004006 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! palpiger relationship: continuous_with AISM:0004002 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mental-premental conjunctiva relationship: continuous_with AISM:0004014 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! premental-palpigeral conjunctiva relationship: continuous_with AISM:0004015 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! premental-paraglossal conjunctiva relationship: continuous_with AISM:0004016 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! premental-glossal conjunctiva relationship: part_of AISM:0000087 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labium [Term] id: AISM:0000058 name: prepectus {creation_date="2020-11-11"} def: "The sclerite that is posterior to the pronotum and receives the site of attachment of the dilutor muscle of the first thoracic spiracle." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"} is_a: AISM:0000003 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite is_a: UBERON:0000061 ! anatomical structure [Term] id: AISM:0000059 name: pronotum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Pronotum: prothoracic tergum.\""} def: "The notum or sclerite on the dorsal region of the prothorax that is attached to cranial muscles, procoxal muscles, contiuous posterioirly with the neck membrane and with pronoto-propleural conjunctiva and not adjacent (not touching) to the procoxa." [] {term:modified="2022-03-09", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-03-18"} is_a: AISM:0000003 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite is_a: AISM:0004128 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! notum is_a: UBERON:0000061 ! anatomical structure relationship: anteriorly_connected_to AISM:0000098 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! neck membrane relationship: attaches_to AISM:0000080 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect cranial muscle relationship: attaches_to AISM:0000145 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! procoxal muscle relationship: continuous_with AISM:0004220 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! pronoto-propleural conjunctiva [Term] id: AISM:0000060 name: labial palpomere {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the mere that is part of the labial palpus." [] {term:modified="2021-12-08", creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000073 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mere relationship: part_of AISM:0000024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labial palpus property_value: IAO:0000589 "cuticle of labial palpomere" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000061 name: prosternum def: "The sclerite on the ventral region of the prothorax that bears the profurca and is attached to the propleuro-prosternal conjunctiva." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0004130 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! sternum relationship: continuous_with AISM:0004202 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! propleuro-prosternal conjunctiva relationship: has_part AISM:0000143 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! profurca [Term] id: AISM:0000062 name: ring sclerite def: "The sclerite that is cylindrical and encircles and is encircled by conjunctiva." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"} is_a: AISM:0000003 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite relationship: AISM:0000078 AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircles conjunctiva relationship: AISM:0000079 AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by conjunctiva relationship: has_characteristic PATO:0001873 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cylindrical [Term] id: AISM:0000063 name: appendage segment {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The ring sclerite that is part of an appendage and is attached to muscle." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"} is_a: AISM:0000062 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! ring sclerite relationship: continuous_with UBERON:0014895 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! somatic muscle relationship: part_of AISM:0000029 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect appendage property_value: IAO:0000589 "cuticle of appendage segment" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000064 name: mesocoxa {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of the mid leg that is attached to the latero-ventral region of the mesothorax by the basal mesocoxal conjunctiva." [] {term:modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0000077 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coxa relationship: AISM:0000079 AISM:0000103 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by basal mesocoxal conjunctiva relationship: part_of AISM:0000035 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mid leg property_value: IAO:0000589 "cuticle of mesocoxa" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000065 name: metacoxa {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of the hind leg that is attached to the latero-ventral region of the metathorax by the basal metacoxal conjunctiva." [] {term:modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0000077 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coxa relationship: AISM:0000079 AISM:0000104 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by basal metacoxal conjunctiva relationship: part_of AISM:0000036 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! hind leg property_value: IAO:0000589 "cuticle of metacoxa" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000066 name: procoxa {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of the fore leg that is attached to the latero-ventral region of the prothorax by the basal procoxal conjunctiva." [] {term:modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0000077 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coxa relationship: AISM:0000079 AISM:0000106 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by basal procoxal conjunctiva relationship: part_of AISM:0000034 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! fore leg property_value: IAO:0000589 "cuticle of procoxa" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000067 name: protibia {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of a fore leg attached to the distal margin of the profemur by the profemoro-protibial conjunctiva." [] {creation_date="2021-04-03", term:modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000075 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tibia relationship: AISM:0000079 AISM:0004179 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by profemoro-protibial conjunctiva relationship: part_of AISM:0000034 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! fore leg property_value: IAO:0000589 "cuticle of protibia" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000068 name: mesotibia {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of a mid leg attached to the distal margin of the mesofemur by the mesofemoro-mesotibial conjunctiva." [] {creation_date="2021-04-03", term:modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000075 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tibia relationship: AISM:0000079 AISM:0004180 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by mesofemoro-mesotibial conjunctiva relationship: part_of AISM:0000035 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mid leg property_value: IAO:0000589 "cuticle of mesotibia" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000069 name: metatibia {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of a hind leg attached to the distal margin of the metafemur by the metafemoro-metatibial conjunctiva." [] {creation_date="2021-04-03", term:modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000075 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tibia relationship: AISM:0000079 AISM:0004181 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by metafemoro-metatibial conjunctiva relationship: part_of AISM:0000036 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! hind leg property_value: IAO:0000589 "cuticle of metatibia" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000070 name: profemur {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of a fore leg attached to the distal margin of the protrochanter by the protrochantero-profemoral conjunctiva." [] {term:modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0000076 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! femur relationship: AISM:0000079 AISM:0000123 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by procoxal-protrochanteral conjunctiva relationship: part_of AISM:0000034 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! fore leg property_value: IAO:0000589 "cuticle of profemur" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000071 name: mesofemur {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of a mid leg attached to the distal margin of the mesotrochanter by the mesotrochantero-mesofemoral conjunctiva." [] {term:modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0000076 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! femur relationship: AISM:0000079 AISM:0000124 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by mesocoxal-mesotrochanteral conjunctiva relationship: part_of AISM:0000035 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mid leg property_value: IAO:0000589 "cuticle of mesofemur" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000072 name: metafemur {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of a hind leg attached to the distal margin of the metatrochanter by the metatrochantero-metafemoral conjunctiva." [] {term:modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0000076 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! femur relationship: AISM:0000079 AISM:0000125 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by metacoxal-metatrochanteral conjunctiva relationship: part_of AISM:0000036 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! hind leg property_value: IAO:0000589 "cuticle of metafemur" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000073 name: mere {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The ring sclerite that is part of an appendage and is not attached to somatic muscle." [] {term:modified="2021-12-08", creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000062 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! ring sclerite relationship: part_of AISM:0000029 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect appendage property_value: IAO:0000589 "cuticle of mere" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000074 name: tarsomere {AISM:0000171="\"Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Tarsomere: subelement of tarsus in Insecta; number often taxon-specific, sometimes differing on legs of different segments (diagnostic value: tarsal formula).\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the mere that is part of the tarsus." [] {term:modified="2021-12-08", creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000073 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! mere relationship: part_of AISM:0004169 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tarsus property_value: IAO:0000589 "cuticle of tarsomere" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000075 name: tibia {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Tibia: 4th element of leg; usually cylindrical and equipped with paired terminal spurs, often with rows of spines.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of a leg attached to the distal margin of the femur by the femoro-tibial conjunctiva." [] {creation_date="2021-04-03", term:modified="2021-12-08", comment="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000063 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! appendage segment relationship: AISM:0000079 AISM:0004178 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by femoro-tibial conjunctiva relationship: has_characteristic PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired relationship: part_of AISM:0000031 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect leg property_value: IAO:0000589 "cuticle of tibia" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000076 name: femur {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Femur: 3rd element of leg, often largest part.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of a leg attached to the distal margin of the trochanter by the trochantero-femoral conjunctiva." [] {term:modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0000063 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! appendage segment relationship: AISM:0000079 AISM:0004174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by trochantero-femoral conjunctiva relationship: has_characteristic PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired relationship: part_of AISM:0000031 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect leg property_value: IAO:0000589 "cuticle of femur" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000077 name: coxa {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Coxa: basal element of leg; articulated with pleural, sternal and usually also trochantinal elements of thoracic segment.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of the leg that is attached to the latero-ventral region of the insect thorax by the basal coxal conjunctiva." [] {term:modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0000063 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! appendage segment relationship: AISM:0000079 AISM:0000173 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by basal coxal conjunctiva relationship: has_characteristic PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired relationship: part_of AISM:0000031 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect leg property_value: IAO:0000589 "cuticle of coxa" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000080 name: insect cranial muscle def: "The somatic muscle that is attached to the head capsule." [] {creation_date="2021-04-04", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: UBERON:0014895 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932", term:modified="2021-12-13"} ! somatic muscle relationship: attaches_to AISM:0000019 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! head capsule [Term] id: AISM:0000081 name: cranio-antennal muscle def: "The somatic muscle that is attached to the head capsule and the antenna." [] {creation_date="2021-04-04", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932", term:modified="2021-12-13"} is_a: AISM:0000080 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranial muscle relationship: attaches_to AISM:0000032 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! antenna [Term] id: AISM:0000082 name: cranio-mandibular muscle def: "The somatic muscle that is attached to the head capsule and the insect mandible." [] {creation_date="2021-04-04", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932", term:modified="2021-12-13"} is_a: AISM:0000080 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect cranial muscle relationship: attaches_to AISM:0000043 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect mandible [Term] id: AISM:0000083 name: cranio-labial muscle def: "The somatic muscle that is attached to the head capsule and the labium." [] {creation_date="2021-04-04", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000080 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranial muscle relationship: attaches_to AISM:0000087 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! labium [Term] id: AISM:0000084 name: cranio-labral muscle def: "The somatic muscle that is attached to the head capsule and the labrum." [] {creation_date="2021-04-04", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932", term:modified="2021-12-13"} is_a: AISM:0000080 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranial muscle relationship: attaches_to AISM:0000042 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! labrum [Term] id: AISM:0000085 name: mesocoxal muscle {creation_date="2020-11-11"} def: "The coxal muscle of the mesocoxa." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000086 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coxal muscle relationship: attaches_to AISM:0000064 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! mesocoxa [Term] id: AISM:0000086 name: coxal muscle def: "The somatic muscle that inserts in the coxa." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21", term:modified="2021-12-13"} is_a: AISM:0002064 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect leg muscle relationship: attaches_to AISM:0000077 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coxa property_value: curator_notes "All of the coxal muscles, except the second sternal-metacoxal muscle, are attached to the thorax." xsd:string {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} [Term] id: AISM:0000087 name: labium {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"The labium or lower lip forms the posterior (orthognathous head) or ventral (prognathous head) closure of the preoral space and of the salivarium. It is homologous to the maxilla (2nd maxilla) of crustaceans, but its proximal\nparts form a structural unit without a recognizable median line or suture.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the mouthpart appendage composed of the cuticle of submentum, which is attached by the submental-mental conjunctiva to the cuticle of mentum, which is attached by the mental-premental conjunctiva to the cuticle of prementum, which is attached to the cuticle of palpiger by the premental-palpigeral conjunctiva, the cuticle of paraglossa by the premental-paraglossal conjunctiva, and the cuticle of glossa by the premental-glossal conjunctiva; the cuticle of palpiger is attached by the palpigero-palpal conjunctiva to the cuticle of labial palpus." [] {term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000165 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! mouthpart relationship: has_part AISM:0000024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labial palpus relationship: has_part AISM:0000048 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! ligula relationship: has_part AISM:0000057 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prementum relationship: has_part AISM:0004002 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mental-premental conjunctiva relationship: has_part AISM:0004004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect mentum relationship: has_part AISM:0004005 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! submentum relationship: has_part AISM:0004006 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! palpiger relationship: has_part AISM:0004013 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! submental-mental conjunctiva relationship: has_part AISM:0004014 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! premental-palpigeral conjunctiva relationship: has_part AISM:0004015 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! premental-paraglossal conjunctiva relationship: has_part AISM:0004016 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! premental-glossal conjunctiva relationship: has_part AISM:0004017 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! palpigero-palpal conjunctiva property_value: IAO:0000589 "cuticle of labium" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000088 name: eye cuticle {creation_date="2020-11-11"} def: "The elastic cuticle of the head capsule that is transparent and covers the eye." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000007 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! elastic cuticle relationship: has_characteristic PATO:0000964 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! transparent relationship: part_of AISM:0000019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! head capsule [Term] id: AISM:0000089 name: insect ligament {creation_date="2020-11-11", IAO:0000232="Modified 2023-01-09 to specify insect ligament.\njgiron https://orcid.org/0000-0002-0851-6883"} def: "The resilin rich region that connects two sclerites." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"} is_a: AISM:0000007 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! elastic cuticle relationship: continuous_with AISM:0000003 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite relationship: part_of AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva [Term] id: AISM:0000090 name: cuticular tendon {AISM:0000171="Klass K-D (2001) The female abdomen of the viviparous earwig Hemimerus vosseleri (Insecta: Dermaptera: Hemimeridae), with a discussion of the postgenital abdomen of Insecta. Zoological Journal of the Linnean Society 131: 251–307. \n\nhttps://doi.org/10.1111/j.1096-3642.2001.tb02239.x \n\n\"tendon is used herein to designate membranous internal cuticular projections\""} def: "The apodeme of elastic cuticle that is continuous with somatic muscle." [] {x_1.1:contributor="2022-06-22", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000007 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! elastic cuticle is_a: AISM:0000188 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! apodeme relationship: continuous_with UBERON:0014895 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! somatic muscle property_value: curator_notes "The usually cylindircal evagination of the cuticle that is resilin rich and is continuous with somatic muscles." xsd:string {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-11-11"} [Term] id: AISM:0000091 name: insect trachea {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Trachea: tube-shaped elements of the tracheal system.\"", IAO:0000232="Modified 2023-01-09 to specify insect trachea.\njgiron https://orcid.org/0000-0002-0851-6883"} def: "The branching invagination of elastic cuticle that is cylindrical and contains taenidia." [] {creation_date="2020-11-11", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000007 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! elastic cuticle is_a: AISM:0000136 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! branching cuticular invagination relationship: has_characteristic PATO:0001873 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cylindrical relationship: has_part AISM:0000140 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! taenidium [Term] id: AISM:0000093 name: hypopharynx {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Hypopharynx: median unpaired lobe between mouthparts and epipharynx; anterior (dorsal) surface continuous with anterior pharynx.\""} def: "The conjunctiva of the insect head that is attached to the salivarium and to the oral foraminal conjunctiva." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: continuous_with AISM:0000099 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! oral foraminal conjunctiva relationship: continuous_with AISM:0000159 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! salivarium relationship: part_of AISM:0000107 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect head [Term] id: AISM:0000094 name: mesopleuro-metapleural conjunctiva def: "The conjunctiva of the insect thorax that joins the mesopleuron and the metapleuron." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: continuous_with AISM:0000119 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metapleuron relationship: continuous_with AISM:0004186 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesopleuron relationship: part_of AISM:0000108 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect thorax [Term] id: AISM:0000095 name: metasterno-metacoxal conjunctiva def: "The conjunctiva of the mesothorax that joins the metasternum and the metacoxa." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: continuous_with AISM:0000065 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metacoxa relationship: continuous_with AISM:0004232 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metasternum relationship: part_of AISM:0004127 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metathorax [Term] id: AISM:0000096 name: prosternal-procoxal conjunctiva def: "The conjunctiva of the prothorax that joins the prosternum and the procoxa." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: continuous_with AISM:0000061 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prosternum relationship: continuous_with AISM:0000066 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! procoxa relationship: part_of AISM:0004125 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prothorax [Term] id: AISM:0000097 name: metapleuro-metacoxal conjunctiva def: "The conjunctiva of the metathorax that joins the metapleuron and the metacoxa." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: continuous_with AISM:0000065 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metacoxa relationship: continuous_with AISM:0000119 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metapleuron relationship: part_of AISM:0004127 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metathorax [Term] id: AISM:0000098 name: neck membrane def: "The conjuctiva that is continuous with the posterior margin of the head capsule and with the anterior margin of the prothorax, and bears cervical sclerites." [] {creation_date="2020-11-11", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", term:modified="2022-06-27"} synonym: "cervical membrane" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Cervical membrane: membrane connecting the head and prothorax.\""} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: AISM:0000078 AISM:0004141 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles cervical sclerite [Term] id: AISM:0000099 name: oral foraminal conjunctiva def: "The conjunctiva of the insect head that connects the head capsule and the mouthparts." [] {creation_date="2021-04-03", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: adjacent_to AISM:0000019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! head capsule relationship: adjacent_to AISM:0000165 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mouthpart relationship: part_of AISM:0000107 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect head [Term] id: AISM:0000100 name: pronoto-mesonotal conjunctiva def: "The conjunctiva of the insect thorax that joins the pronotum and the mesonotum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: continuous_with AISM:0000052 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesonotum relationship: continuous_with AISM:0000059 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pronotum relationship: part_of AISM:0000108 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect thorax [Term] id: AISM:0000101 name: pronoto-mesopectal conjunctiva def: "The conjunctiva that is attached to the pronotum and the mesopectus." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: continuous_with AISM:0000053 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesopectus relationship: continuous_with AISM:0000059 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pronotum [Term] id: AISM:0000102 name: ring conjunctiva def: "The conjunctiva that encircles a ring sclerite." [] {creation_date="2021-04-03", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: AISM:0000078 AISM:0000062 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircles ring sclerite [Term] id: AISM:0000103 name: basal mesocoxal conjunctiva def: "The conjunctiva that encircles the mesocoxa and connects it to the ventral and lateral regions of the mesothorax." [] {creation_date="2020-11-11", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000173 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! basal coxal conjunctiva relationship: continuous_with AISM:0004126 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesothorax [Term] id: AISM:0000104 name: basal metacoxal conjunctiva def: "The conjunctiva that encircles the metacoxa and connects it to the ventral and lateral regions of the metathorax." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0000173 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! basal coxal conjunctiva relationship: continuous_with AISM:0004127 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metathorax [Term] id: AISM:0000105 name: epipharynx {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Epipharynx: semimembranous or membranous posterior wall of labrum and roof of cibarium.\""} def: "The conjunctiva of the insect head that is connected to the oral foraminal conjunctiva and to the distal margin of the labrum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: continuous_with AISM:0000099 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! oral foraminal conjunctiva relationship: part_of AISM:0000107 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect head [Term] id: AISM:0000106 name: basal procoxal conjunctiva def: "The conjunctiva that encircles the procoxa and connects it to the ventral and lateral regions of the prothorax." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0000173 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! basal coxal conjunctiva relationship: continuous_with AISM:0004125 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prothorax [Term] id: AISM:0000107 name: insect head {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"The head is a compact and complex tagma with a concentration of a broad array of structures und functions. It is equipped with sense organs such as the highly complex compound eyes and the antennae, an elaborate set of mouthparts, and a complex muscle apparatus. It also contains central elements of the nervous system, the anterior part of the digestive tract including the cibarium (preoral cavity) and the salivarium, and also neurohaemal organs.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticular region that is anterior (distal) to the neck membrane (encircled by the neck membrane) and contains the head capsule, the antenna, the eyes, mouthparts and surrounds the brain." [] {creation_date="2020-11-11", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000174 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect region of cuticle is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:6007289 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect tagmatic subdivision of integument intersection_of: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! insect region of cuticle intersection_of: UBERON:6007289 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! insect tagmatic subdivision of integument intersection_of: anterior_to AISM:0000098 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! neck membrane intersection_of: has_part AISM:0000019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! head capsule relationship: AISM:0000079 AISM:0000098 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by neck membrane relationship: anterior_to AISM:0000098 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! neck membrane relationship: has_part AISM:0000019 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! head capsule relationship: has_part AISM:0000032 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! antenna relationship: has_part AISM:0000093 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! hypopharynx relationship: has_part AISM:0000099 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! oral foraminal conjunctiva relationship: has_part AISM:0000105 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! epipharynx relationship: has_part AISM:0000112 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cranio-antennal conjunctiva relationship: has_part AISM:0000165 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mouthpart relationship: surrounds UBERON:0000955 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! brain property_value: IAO:0000589 "cuticle of insect head" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000108 name: insect thorax {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The region of cuticle that is connected to some muscles of the fore and hind legs and is posterior to the neck membrane and aterior to the first abdominal spiracle." [] {creation_date="2020-11-11", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000174 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect region of cuticle is_a: UBERON:6007289 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect tagmatic subdivision of integument intersection_of: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! insect region of cuticle intersection_of: UBERON:6007289 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! insect tagmatic subdivision of integument intersection_of: anterior_to AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! insect abdomen intersection_of: posterior_to AISM:0000098 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! neck membrane relationship: anterior_to AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen relationship: has_part AISM:0000085 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! mesocoxal muscle relationship: has_part AISM:0000145 ! procoxal muscle relationship: has_part AISM:0004125 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prothorax relationship: has_part AISM:0004126 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesothorax relationship: has_part AISM:0004127 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metathorax relationship: posterior_to AISM:0000098 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! neck membrane property_value: curator_notes "The hind leg muscles sometimes attach to the second abdominal sternite. The abdominal sopiracles are different in their structure from tghe thoracic spiracles as they are opened and closed by two articulating sclerites that are moved by two sets of muscles whereas the thoracic spiracles are closed by only one occlusor muscle and opened by the flexibility of the distal tracheal region. The border between the thorax and the abdomen is sometimes marked by the anterior first abdmonial tergal conjunctiva. In Hymenoptera, the border between the abdomen and the thorax cannot be defined as the anterior first abdmonial tergal conjunctiva is absent, the sclerite that receives muscles from the metacoxa also contains the first abdominal spiracle." xsd:string {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-11-11"} property_value: IAO:0000589 "cuticle of insect thorax" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000109 name: insect abdomen {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The region of the cuticle that is an insect tagmatic subdivision of the integument, posterior to the thorax." [] {creation_date="2020-11-11", IAO:0000232="Modified 2024-01-25: added 'insect tagmatic subdivision of integument'.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000174 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect region of cuticle is_a: UBERON:6007289 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect tagmatic subdivision of integument intersection_of: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! insect region of cuticle intersection_of: UBERON:6007289 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! insect tagmatic subdivision of integument intersection_of: posterior_to AISM:0000108 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! insect thorax relationship: depiction https://ndownloader.figshare.com/files/6014256/preview/6014256/preview.jpg relationship: has_part AISM:0004055 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! preabdomen relationship: has_part AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postabdomen relationship: posterior_to AISM:0000108 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect thorax property_value: curator_notes "The thorax is defined based on local properties (e.g. attachment sites of coxal muscles) and therefore we can reference this class for the definition of the abdomen." xsd:string {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-11-11"} property_value: IAO:0000589 "cuticle of insect abdomen" xsd:string {comment="2023-04-13"} [Term] id: AISM:0000110 name: cardo-stipital conjunctiva def: "The conjunctiva of the insect maxilla that connects the cardo and the stipes." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: continuous_with AISM:0000018 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cardo relationship: continuous_with AISM:0000111 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! stipes relationship: part_of AISM:0000044 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect maxilla [Term] id: AISM:0000111 name: stipes {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Stipes: second element of maxilla, connected with cardo by a hinge; bearing endite lobes (galea and lacinia) and maxillary palp.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the sclerite of the insect maxilla that is attached to the cuticle of cardo by the cardo-stipital conjunctiva, attached to the cuticle of lacinia by the stipito-lacinial conjunctiva, attached to the cuticle of palpifer by the stipito-palpiferal conjunctiva, and attached to the cuticle of galea by the stipito-galeal conjunctiva." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000003 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite relationship: adjacent_to AISM:0000018 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cardo relationship: adjacent_to AISM:0000023 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! galea relationship: adjacent_to AISM:0000026 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! lacinia relationship: adjacent_to AISM:0004001 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! palpifer relationship: continuous_with AISM:0000110 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cardo-stipital conjunctiva relationship: continuous_with AISM:0004009 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! stipito-lacinial conjunctiva relationship: continuous_with AISM:0004010 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! stipito-palpiferal conjunctiva relationship: continuous_with AISM:0004011 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! stipito-galeal conjunctiva relationship: part_of AISM:0000044 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect maxilla property_value: IAO:0000589 "cuticle of stipes" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000112 name: cranio-antennal conjunctiva def: "The conjunctiva that encircles the base of the antenna (scape) and is encircled by the head capsule as the antennal foramen." [] {creation_date="2020-11-11", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: AISM:0000078 AISM:0000113 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircles scapus relationship: AISM:0000079 AISM:0000019 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by head capsule relationship: continuous_with AISM:0000019 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! head capsule [Term] id: AISM:0000113 name: scapus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\nScapus: basal element of antenna, with two muscles attached to the pedicellus.", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of the antenna that is connected to the head capsule and the antennifer by the basal antennal conjunctiva." [] {term:modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} synonym: "antennomere 1" EXACT [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000063 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! appendage segment is_a: AISM:0004266 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! antennomere relationship: adjacent_to AISM:0000019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! head capsule relationship: adjacent_to AISM:0000190 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! antennifer relationship: continuous_with AISM:0000112 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cranio-antennal conjunctiva property_value: IAO:0000589 "cuticle of scapus" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000114 name: scapal-pedicellar conjunctiva def: "The conjunctiva of the antenna that connects the scapus and the pedicellus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000102 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! ring conjunctiva relationship: AISM:0000078 AISM:0000115 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles pedicellus relationship: AISM:0000079 AISM:0000113 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by scapus relationship: part_of AISM:0000032 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! antenna [Term] id: AISM:0000115 name: pedicellus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Pedicellus: second antennal segment in Insecta; contains Johnston’s organ and lacks intrinsic muscles.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of the antenna that is attached to the scapus by the scapal-pedicellar conjunctiva." [] {term:modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} synonym: "antennomere 2" EXACT [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000063 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! appendage segment is_a: AISM:0004266 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! antennomere relationship: AISM:0000079 AISM:0000114 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by scapal-pedicellar conjunctiva property_value: IAO:0000589 "cuticle of pedicellus" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000116 name: flagellomere {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the mere that is part of the antenna." [] {term:modified="2021-12-08", creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004266 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! antennomere relationship: distal_to AISM:0000115 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! pedicellus property_value: curator_notes "Given the high number of flagellomeres occurring in some taxa, Arabic numerals are used instead of Roman numerals for practicality reasons." xsd:string {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} property_value: IAO:0000589 "cuticle of flagellomere" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000117 name: flagellomere 1 {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Flagellomere: segment of the flagellum.\"", IAO:0000232="Modified 2023-05-05: \"first\" replaced with \"1\"\ngmontanaro https://orcid.org/0000-0003-0836-1364", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the first flagellomere of the antenna, attached to the pedicel by the pedicel-first flagellomere conjunctiva." [] {term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} synonym: "antennomere 3" EXACT [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000116 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! flagellomere relationship: AISM:0000079 AISM:0000118 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by pedicellar-first flagellomeral conjunctiva property_value: IAO:0000589 "cuticle of first flagellomere" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000118 name: pedicellar-first flagellomeral conjunctiva def: "The conjunctiva of the antenna that connects the pedicellus and the first flagellomere." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: AISM:0000078 AISM:0000117 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircles flagellomere 1 relationship: AISM:0000079 AISM:0000115 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by pedicellus relationship: part_of AISM:0000032 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! antenna [Term] id: AISM:0000119 name: metapleuron def: "The region of the cuticle on the lateral region of the metathorax that is attached to the metanotum and the metasternum, and is attached to the metacoxa by the metacoxal muscle and the basal metacoxal conjunctiva." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004129 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! pleuron relationship: adjacent_to AISM:0000169 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metanotum relationship: adjacent_to AISM:0004232 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metasternum relationship: continuous_with AISM:0000104 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! basal metacoxal conjunctiva relationship: continuous_with AISM:0000146 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metacoxal muscle [Term] id: AISM:0000120 name: propleuro-procoxal conjunctiva def: "The conjunctiva of the prothorax that joins the propleuron and the procoxa." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: continuous_with AISM:0000066 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! procoxa relationship: continuous_with AISM:0004142 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! propleuron relationship: part_of AISM:0004125 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prothorax [Term] id: AISM:0000121 name: mesosternum def: "The sclerite on the ventral region of the mesothorax that bears the mesofurca and is attached to the mesopleuro-mesosternal conjunctiva." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0004130 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! sternum relationship: continuous_with AISM:0004231 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesopleuro-mesosternal conjunctiva relationship: has_part AISM:0000141 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesofurca [Term] id: AISM:0000123 name: procoxal-protrochanteral conjunctiva def: "The conjunctiva of the fore leg joining the distal margin of a procoxa and the proximal margin of a protrochanter." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0004170 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! coxal-trochanteral conjunctiva relationship: part_of AISM:0000034 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! fore leg [Term] id: AISM:0000124 name: mesocoxal-mesotrochanteral conjunctiva def: "The conjunctiva of the mid leg joining the distal margin of a mesocoxa and the proximal margin of a mesotrochanter." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0004170 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coxal-trochanteral conjunctiva relationship: part_of AISM:0000035 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mid leg [Term] id: AISM:0000125 name: metacoxal-metatrochanteral conjunctiva def: "The conjunctiva of the hind leg joining the distal margin of a metacoxa and the proximal margin of a metatrochanter." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0004170 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! coxal-trochanteral conjunctiva relationship: part_of AISM:0000036 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! hind leg [Term] id: AISM:0000126 name: socket membrane {creation_date="2020-11-11"} def: "The conjunctiva that corresponds to one epithelial cell and surrounds a sclerotized unicellular cuticular evagination." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: RO:0002008 CL:0000066 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coincident with epithelial cell property_value: curator_notes "Should coincide with 'exactly one' epithelial cell, but that violates OWL specs." xsd:string {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-26"} [Term] id: AISM:0000127 name: unicellular cuticular evagination def: "The cuticular evagination that corresponds to the evagination on the membrane of a single cell and not to the evagination of a cell layer." [] {creation_date="2020-11-11", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000027 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular evagination relationship: RO:0002008 CL:0000066 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coincident with epithelial cell property_value: curator_notes "Should coincide with 'exactly one' epithelial cell, but that violates OWL specs." xsd:string {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-26"} [Term] id: AISM:0000128 name: multicellular cuticular evagination {creation_date="2020-11-11"} def: "The region of cuticle that corresponds to the evagination of the single layer epithelium." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"} is_a: AISM:0000027 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular evagination [Term] id: AISM:0000130 name: uniporous sensillum {IAO:0000232="Modified 2023-01-11: moved under cuticular sensilla; added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883"} def: "The seta that has one opening distally." [] {creation_date="2020-11-11", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0004304 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular sensilla relationship: has_part AISM:0000039 {IAO:0000232="Modified 2023-01-11: added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular seta relationship: has_part AISM:0000177 {IAO:0000232="Modified 2023-01-11: added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! pore canal property_value: curator_notes "Should coincide with 'exactly one' pore canal, but that violates OWL specs." xsd:string {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-23"} [Term] id: AISM:0000131 name: multiporous sensillum {creation_date="2020-11-11", IAO:0000232="Modified 2023-01-11: moved under cuticular sensilla; added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Ando, T., Sekine, S., Inagaki, S., Misaki, K., Badel, L., Moriya, H., Sami, M.M., Itakura, Y., Chihara, T., Kazama, H. and Yonemura, S., 2019. Nanopore formation in the cuticle of an insect olfactory sensillum. Current Biology, 29(9), pp.1512-1520.\nhttps://www.sciencedirect.com/science/article/pii/S0960982219303410#fig4"} def: "The seta that has multiple cuticular pores (openings of class III exocrine glands)." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"} is_a: AISM:0004304 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular sensilla relationship: has_characteristic PATO:0000984 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! porous relationship: has_part AISM:0000039 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! cuticular seta [Term] id: AISM:0000132 name: placoid sensillum {creation_date="2020-11-11"} def: "The multiporous plate that is elongated." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"} is_a: AISM:0000133 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! multiporous plate relationship: has_characteristic PATO:0001154 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! elongated [Term] id: AISM:0000133 name: multiporous plate {creation_date="2020-11-11"} def: "The multiporous sensillum that is flat." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"} is_a: AISM:0000131 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! multiporous sensillum relationship: has_characteristic PATO:0000407 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! flat [Term] id: AISM:0000134 name: cuticular exocrine gland duct {creation_date="2020-11-11", term:modified="2021-12-10"} def: "The branching cuticular invagination that corresponds to the invagination of the membrane of a single cell and does not contain taenidia." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"} is_a: AISM:0000136 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! branching cuticular invagination relationship: RO:0002008 CL:0000066 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coincident with epithelial cell property_value: curator_notes "Should coincide with 'exactly one' epithelial cell, but that violates OWL specs." xsd:string {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-26"} [Term] id: AISM:0000135 name: insect spiracle {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Spiracle: external opening of the tracheal system.\"", term:modified="2023-01-09", IAO:0000232="Modified 2023-01-09: specifying insect spiracle.\njgiron https://orcid.org/0000-0002-0851-6883"} def: "The region of the cuticle that is continuous to the proximal region of a trachea and can be closed by muscles." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"} is_a: AISM:0000174 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect region of cuticle is_a: UBERON:0000061 ! anatomical structure relationship: attaches_to UBERON:0014895 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! somatic muscle [Term] id: AISM:0000136 name: branching cuticular invagination def: "The cuticular ivagination that ramifies into umerous branches." [] {creation_date="2020-11-11", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000006 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular invagination relationship: has_characteristic PATO:0000402 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! branched property_value: curator_notes "Branching cuticular invaginations porvide important models for branchig morphogenesis." xsd:string {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-11-11"} [Term] id: AISM:0000137 name: malphigian tube {creation_date="2020-11-11"} def: "The branching cuticular invagination that is located between the mid and hindgut." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"} xref: http://purl.obolibrary.org/obo/UBERON_0001054 is_a: AISM:0000136 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! branching cuticular invagination [Term] id: AISM:0000138 name: cuticular apophysis {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Apophysis: hollow cuticular invagination.\"", term:modified="2021-12-10"} def: "The cuticular invagination that is hollow." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"} is_a: AISM:0000006 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular invagination is_a: AISM:0000188 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! apodeme relationship: RO:0002008 AISM:0000193 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coincident with cuticular pit property_value: curator_notes "The apophysis in HAO refers to an ivagination of the cuticle that is cylindrical as opposed to a ridge that is elongate. Beutel et al. 2014 differentiate apodemes from apophyses in that apodemes are solid and apophyses are hollow." xsd:string {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-11-11"} [Term] id: AISM:0000140 name: taenidium {creation_date="2020-11-11", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Taenidium: spiral-shaped strengthening ridge of the tracheae.\""} def: "The coiled ridge in the wall of the trachea." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"} is_a: AISM:0000158 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular ridge relationship: has_characteristic PATO:0000404 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coiled [Term] id: AISM:0000141 name: mesofurca def: "The furca of the mesothorax that is attached to the mesocoxa via muscle." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000144 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! furca relationship: part_of AISM:0004126 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesothorax [Term] id: AISM:0000142 name: metafurca def: "The furca of the metathorax that is attached to the metacoxa via muscle." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000144 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! furca relationship: part_of AISM:0004127 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metathorax [Term] id: AISM:0000143 name: profurca def: "The furca of the prothorax that is attached to the procoxa via muscle." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000144 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! furca relationship: part_of AISM:0004125 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prothorax [Term] id: AISM:0000144 name: furca {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Furca (=sternal apophysis, endosternite): endoskeletal element (entapophysis) of furcasternum; paired furcal arms often connected with pleural ridge by short muscle.\""} def: "The apophysis that is located ventromedially on the thorax and is connected to the coxa via muscles." [] {creation_date="2020-11-11", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} synonym: "endosternite" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Furca (=sternal apophysis, endosternite): endoskeletal element (entapophysis) of furcasternum; paired furcal arms often connected with pleural ridge by short muscle.\""} is_a: AISM:0000136 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! branching cuticular invagination is_a: AISM:0000138 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular apophysis is_a: UBERON:0000061 ! anatomical structure relationship: part_of AISM:0000108 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect thorax relationship: part_of BSPO:0000112 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! ventro-medial region [Term] id: AISM:0000145 name: procoxal muscle {creation_date="2020-11-11"} def: "The coxal muscle of the procoxa." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000086 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coxal muscle relationship: attaches_to AISM:0000066 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! procoxa [Term] id: AISM:0000146 name: metacoxal muscle {creation_date="2020-11-11"} def: "The coxal muscle of the metacoxa." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000086 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coxal muscle relationship: attaches_to AISM:0000065 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! metacoxa [Term] id: AISM:0000147 name: femoral muscle def: "The somatic muscle that inserts in the femur." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", term:modified="2021-12-13"} is_a: AISM:0002064 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect leg muscle relationship: attaches_to AISM:0000076 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! femur [Term] id: AISM:0000148 name: tibial muscle def: "The somatic muscle that inserts in the tibia." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", term:modified="2021-12-13"} is_a: AISM:0002064 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect leg muscle relationship: attaches_to AISM:0000075 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! tibia [Term] id: AISM:0000149 name: pretarsal muscle def: "The somatic muscle that inserts in the pretarsus." [] {creation_date="2020-11-11", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", term:modified="2021-12-13"} is_a: AISM:0002064 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect leg muscle relationship: attaches_to AISM:0000047 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! pretarsus property_value: curator_notes "There are usually two muscle bands of the pretarsal muscle, one is arising from the femur, the other from the tibia. The muscle usually inserts on a resilin rich basal sclerite of the pretarsus, the unguitractor plate." xsd:string {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-11-11"} [Term] id: AISM:0000150 name: profemoral muscle def: "The somatic muscle that inserts in the profemur." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", term:modified="2021-12-13"} is_a: AISM:0000147 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! femoral muscle relationship: attaches_to AISM:0000070 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! profemur [Term] id: AISM:0000151 name: mesofemoral muscle def: "The somatic muscle that inserts in the mesofemur." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", term:modified="2021-12-13"} is_a: AISM:0000147 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! femoral muscle relationship: attaches_to AISM:0000071 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! mesofemur [Term] id: AISM:0000152 name: metafemoral muscle def: "The somatic muscle that inserts in the metafemur." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", term:modified="2021-12-13"} is_a: AISM:0000147 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! femoral muscle relationship: attaches_to AISM:0000072 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! metafemur [Term] id: AISM:0000153 name: protibial muscle def: "The somatic muscle that inserts in the protibia." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", term:modified="2021-12-13"} is_a: AISM:0000148 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! tibial muscle relationship: attaches_to AISM:0000067 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! protibia [Term] id: AISM:0000154 name: mesotibial muscle def: "The somatic muscle that inserts in the mesotibia." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", term:modified="2021-12-13"} is_a: AISM:0000148 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! tibial muscle relationship: attaches_to AISM:0000068 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! mesotibia [Term] id: AISM:0000155 name: metatibial muscle def: "The somatic muscle that inserts in the metatibia." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", term:modified="2021-12-13"} is_a: AISM:0000148 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! tibial muscle relationship: attaches_to AISM:0000069 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! metatibia [Term] id: AISM:0000156 name: cuticular fovea {term:modified="2021-12-10"} def: "The cuticular depression that is circular." [] {creation_date="2020-11-11", IAO:0000232="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000005 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular depression relationship: has_characteristic PATO:0000411 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! circular [Term] id: AISM:0000157 name: cuticular groove {term:modified="2021-12-10", IAO:0000232="former 'impression'\nimiko https://orcid.org/0000-0003-2938-9075"} def: "The cuticular depression that is elongated and coincides with the distal side of an insect sclerite." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", IAO:0000232="Modified 2024-01-25: to reflect subclass of definiton\njgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000005 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular depression relationship: has_characteristic PATO:0001154 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! elongated property_value: curator_notes "The cuticular depression (concavity on the surface of the cuticle) that does not correspond to a cuticular invagination (epithelial fold). The cuticule is less thick at the site of a cuticular impression." xsd:string {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-11-11"} [Term] id: AISM:0000158 name: cuticular ridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Ridge: cuticular strengthening ridge.\"\n\"They are not lines of fusion or molting lines.\"(p. 12)", term:modified="2021-12-10"} def: "The invagination on a sclerite that is elongated." [] {creation_date="2020-11-11", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000000 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular internal depression relationship: has_characteristic PATO:0001154 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! elongated relationship: part_of AISM:0000003 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite [Term] id: AISM:0000159 name: salivarium {def="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Salivarium: posterior part of preoral space between hypopharynx and labium, with opening of salivary ducts.\""} def: "The conjunctiva in the head capsule that forms a pouch between the hypopharynx and the labium and bears the exocrine gland duct." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva is_a: AISM:0000160 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular pouch relationship: continuous_with AISM:0000087 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! labium relationship: continuous_with AISM:0000093 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! hypopharynx relationship: continuous_with AISM:0000134 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular exocrine gland duct relationship: part_of AISM:0000019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! head capsule [Term] id: AISM:0000160 name: cuticular pouch {term:modified="2021-12-10"} def: "The invagination of the cuticle that is largely membranous." [] {creation_date="2020-11-12", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000006 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular invagination relationship: has_part AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva [Term] id: AISM:0000161 name: discrimenal lamella def: "The ridge that is in the sagittal line of the ventro-medial region of the thorax." [] {creation_date="2020-11-12", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000158 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular ridge relationship: RO:0002008 BSPO:0000417 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coincident with sagittal plane [Term] id: AISM:0000162 name: cuticular sulcus {term:modified="2021-12-10"} def: "The cuticular depression (concavity on cuticle surface) that corresponds with a cuticular ridge (an elongate cuticular invagination)." [] {creation_date="2020-11-12", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", term:modified="2021-12-10"} is_a: AISM:0000157 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular groove relationship: RO:0002008 AISM:0000158 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coincident with cuticular ridge [Term] id: AISM:0000163 name: discrimen {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Discrimen: longitudinal ridge medially dividing the sternum\""} def: "The longitudinal (parallel to antero-posterior axis) sulcus that corresponds to the discrimenal lamella." [] {creation_date="2020-11-12", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000162 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular sulcus relationship: continuous_with AISM:0000161 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! discrimenal lamella relationship: parallel_to BSPO:0000013 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anterior-posterior axis [Term] id: AISM:0000165 name: mouthpart {creation_date="2020-11-17", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the appendage of the insect head that is encircled by the oral foraminal conjunctiva." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21", term:modified="2021-12-10"} is_a: AISM:0000029 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect appendage relationship: AISM:0000079 AISM:0000099 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by oral foraminal conjunctiva relationship: part_of AISM:0000107 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect head property_value: IAO:0000589 "cuticle of mouthpart" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000166 name: propleuro-procoxal articulation def: "The insect articulation between the propleuron and the procoxa." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000002 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect articulation [Term] id: AISM:0000167 name: articular surface def: "The region of cuticle where two sclerites meet." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect region of cuticle relationship: adjacent_to AISM:0000003 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite [Term] id: AISM:0000168 name: salivary sclerite def: "The sclerite of the salivarium." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000003 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite relationship: part_of AISM:0000159 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! salivarium [Term] id: AISM:0000169 name: metanotum def: "The notum or sclerite on the dorsal region of the metathorax that is posterior to the mesonotum, connected via the metanoto-metapleural conjuntiva to the dorsal margin of the metapleuron, that is not adjacent to the metacoxa, but attached to it by the metacoxal muscle." [] {x_1.1:contributor="jcgiron", creation_date="2021-04-21"} is_a: AISM:0000003 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite is_a: AISM:0004128 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! notum is_a: UBERON:0000061 ! anatomical structure relationship: attaches_to AISM:0000146 {x_1.1:contributor="jcgiron"} ! metacoxal muscle relationship: continuous_with AISM:0004221 {x_1.1:contributor="jcgiron"} ! metanoto-metapleural conjunctiva relationship: posterior_to AISM:0000052 {x_1.1:contributor="jcgiron"} ! mesonotum [Term] id: AISM:0000170 name: metapectus def: "The sclerite that is continuous with the basal metacoxal conjunctiva and the basal wing conjunctiva and contains the metafurca." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"} is_a: AISM:0000003 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite relationship: continuous_with AISM:0000104 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! basal metacoxal conjunctiva relationship: continuous_with AISM:0004203 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! basal wing conjunctiva relationship: has_part AISM:0000142 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! metafurca [Term] id: AISM:0000172 name: intertarsomeral conjunctiva def: "The conjunctiva is encircled by a tarsomere that encircles another tarsomere." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0000102 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! ring conjunctiva relationship: AISM:0000078 AISM:0000074 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles tarsomere relationship: AISM:0000079 AISM:0000074 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by tarsomere relationship: continuous_with AISM:0000074 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tarsomere [Term] id: AISM:0000173 name: basal coxal conjunctiva def: "The conjunctiva that encircles the coxa and connects it to the ventral and lateral thoracic regions." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-11-17"} is_a: AISM:0000102 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! ring conjunctiva relationship: part_of AISM:0000108 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect thorax property_value: curator_notes "These conjunctivae can be used as stable reference points in insects that poseess legs, and can be used to define sclerites on the lateral side of the thorax." xsd:string {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-11-17"} [Term] id: AISM:0000174 name: insect region of cuticle {IAO:0000232="Modified 2023-04-13: added insect to specify.\njgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect region of integument that is part of the chitin-based cuticle." [] {creation_date="2020-11-23", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: BFO:0000004 ! independent continuant relationship: part_of UBERON:0001001 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! chitin-based cuticle relationship: part_of UBERON:6007284 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect region of integument property_value: curator_notes "The AISM focuses on anatomical structures that are part of the insect (chitinous) cuticle. These structures are acellular regions of the integument. Regions of the insect cuticle with different mechanical properties (i.e. increased and descresed flexinility, thickness, and elasticity) are continuous with each other (e.g. sclerites are continuous with conjunctivae or resilin rich regions are continuous with regions with less resilin content)." xsd:string {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-11-23"} [Term] id: AISM:0000177 name: pore canal {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Pore canals: thin perforations of the cuticle.\""} def: "The orifice that is contained by the cuticle and connects the inside of the insect with the outside, is tubular, and whose diameter is smaller than 100 nm." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-02-04"} is_a: UBERON:0000161 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! orifice relationship: AISM:0000079 UBERON:0001002 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by cuticle relationship: has_characteristic PATO:0001873 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cylindrical relationship: RO:0002008 CL:0000066 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coincident with epithelial cell property_value: curator_notes "Should coincide with 'exactly one' epithelial cell, but that violates OWL specs." xsd:string {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-26"} [Term] id: AISM:0000178 name: acantha {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Acanthae: hairs without sockets, one per hypodermal cell.\""} def: "The solid cuticular protrusion that coincides with only one epidermal cell (smaller than the diameter of the epidermal cell)." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-02-04"} is_a: AISM:0000028 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! solid cuticular protrusion relationship: part_of AISM:0000003 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite relationship: RO:0002008 CL:0000362 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coincident with epidermal cell property_value: curator_notes "Should coincide with 'exactly one' epithelial cell, but that violates OWL specs." xsd:string {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-26"} [Term] id: AISM:0000180 name: tergal carina {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2025-03-16"} def: "The cuticular carina on a tergite (or notum)." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2025-03-16"} is_a: AISM:0000501 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2025-03-16"} ! cuticular carina relationship: part_of AISM:0004128 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2025-03-16"} ! notum [Term] id: AISM:0000181 name: tibial spur {creation_date="2025-03-17", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The cuticular spur that is continuous with the distal margin of the tibia." [] {creation_date="2025-03-17", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000040 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2025-03-17"} ! cuticular spur [Term] id: AISM:0000185 name: sensillum chaeticum {IAO:0000232="Modified 2023-01-11: moved under cuticular sensilla; added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Sensillum chaeticum: shorter than sensillum trichodeum, thick-walled.\""} def: "The hairlike seta that is short and thick walled." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-02-08"} is_a: AISM:0004304 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular sensilla relationship: has_characteristic PATO:0002228 {IAO:0000232="Modified 2023-01-11: added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! acuminate relationship: has_part AISM:0000039 {IAO:0000232="Modified 2023-01-11: added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular seta [Term] id: AISM:0000186 name: sensillum trichodeum {IAO:0000232="Modified 2023-01-11: moved under cuticular sensilla; added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Sensillum trichodeum: hair-like sensilla, seta associated with sensory cell.\""} def: "The cuticular seta that is elongated and acuminate." [] {creation_date="2022-06-20", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004304 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular sensilla relationship: has_characteristic PATO:0001154 {IAO:0000232="Modified 2023-01-11: added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! elongated relationship: has_characteristic PATO:0002228 {IAO:0000232="Modified 2023-01-11: added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! acuminate relationship: has_part AISM:0000039 {IAO:0000232="Modified 2023-01-11: added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular seta relationship: has_part AISM:0000039 {IAO:0000232="Modified 2023-01-11: added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular seta property_value: curator_notes "Hairlike seta that is long." xsd:string {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-02-08"} [Term] id: AISM:0000187 name: sensillum coeloconicum {IAO:0000232="Modified 2023-01-11: moved under cuticular sensilla; added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Sensillum coeloconicum: sensillum with modified seta in a cavity, with narrowed external opening of surrounding cuticle.\""} def: "Seta that is located in the middle of a depression with narrowed external opening." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-02-08"} is_a: AISM:0004304 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular sensilla [Term] id: AISM:0000188 name: apodeme {AISM:0000171="Klass K-D (2001) The female abdomen of the viviparous earwig Hemimerus vosseleri (Insecta: Dermaptera: Hemimeridae), with a discussion of the postgenital abdomen of Insecta. Zoological Journal of the Linnean Society 131: 251–307. \n\nhttps://doi.org/10.1111/j.1096-3642.2001.tb02239.x \n\n\"tendon is used herein to designate sclerotized internal cuticular projections\"", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043\n\n\"Apodeme: solid cuticular invagination serving as muscle insertion area.\""} def: "The solid cuticular invagination of a sclerite." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000000 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular internal depression relationship: has_characteristic PATO:0001873 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cylindrical relationship: part_of AISM:0000003 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite [Term] id: AISM:0000189 name: sensillum basiconicum {IAO:0000232="Modified 2023-01-11: moved under cuticular sensilla; added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Sensillum basiconicum: sensillum with rounded, conical seta.\""} def: "The seta that is conical." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004304 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular sensilla relationship: has_characteristic PATO:0002021 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conical relationship: has_part AISM:0000039 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! cuticular seta [Term] id: AISM:0000190 name: antennifer {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Antennifer: small cephalic process articulating with the antenna.\""} def: "The cuticular protrusion of the head capsule thag is continuous with the antenniferal-scapal conjunctiva and adjacent to the cuticle of the scapus" [] {creation_date="2022-06-20", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000008 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular protrusion relationship: adjacent_to AISM:0000113 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! scapus relationship: continuous_with AISM:0004007 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! antenniferal-scapal conjunctiva relationship: part_of AISM:0000019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! head capsule property_value: curator_notes "The cuticular protrusion (process, protuberace) that bears the cranial articular surface of the cranio-antennal articulation." xsd:string {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-02-08"} [Term] id: AISM:0000191 name: tentorium {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Tentorium: cephalic endoskeleton, usually composed of paired anterior, posterior and dorsal tentorial arms and a transverse tentorial bridge (corpotentorium).\""} def: "The solid, paired, branching cuticular invagination of the head capsule that is attached to the antenna and the mouthparts via muscles." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000136 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! branching cuticular invagination is_a: AISM:0000188 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! apodeme is_a: UBERON:0000061 ! anatomical structure relationship: has_characteristic PATO:0040024 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! bilaterally paired relationship: part_of AISM:0000019 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! head capsule property_value: curator_notes "The paired apophysis that connects the posterior (ventral in prognathous head) and anterior (dorsal in prognathous head) walls of the head capsule and serves as site of isertion of atennal and mouthpart muscles." xsd:string {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-02-11"} [Term] id: AISM:0000192 name: tentorio-antennal muscle def: "The insect cranial muscle that is attached to the tentorium and to the antenna." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000080 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect cranial muscle relationship: attaches_to AISM:0000032 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! antenna relationship: attaches_to AISM:0000191 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tentorium [Term] id: AISM:0000193 name: cuticular pit {term:modified="2021-12-10"} def: "The cuticular depression that corresponds to an apophysis." [] {creation_date="2021-02-12", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000156 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular fovea relationship: has_characteristic PATO:0002078 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! hollow relationship: RO:0002008 AISM:0000138 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coincident with cuticular apophysis [Term] id: AISM:0000194 name: anterior tentorial pit {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Anterior tentorial pit (or groove): externally visible invagination area and origin of anterior tentorial arm; adjacent with dorsolateral clypeal margin.\""} def: "The tentorial pit that correspods to the anterior (dorsal in prognathous head) end of the tentorium." [] {creation_date="2021-02-12", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000196 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! tentorial pit relationship: adjacent_to AISM:0004038 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anterior tentorial arm [Term] id: AISM:0000195 name: posterior tentorial pit {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Posterior tentorial pit (or groove): externally visible invagination of posterior part of head capsule and origin of posterior tentorial arm; adjacent with foramen occipitale or gula.\""} def: "The tentorial pit that correspods to the posterior (ventral in prognathous head) end of the tentorium." [] {creation_date="2021-02-12", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000196 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! tentorial pit relationship: continuous_with AISM:0004037 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! posterior tentorial arm [Term] id: AISM:0000196 name: tentorial pit def: "The cuticular pit that correspods to the tentorium." [] {creation_date="2021-02-12", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", term:modified="2021-12-10"} is_a: AISM:0000193 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular pit [Term] id: AISM:0000197 name: arthropod foramen def: "The foramen encircled by insect region of cuticle." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: UBERON:0000161 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! orifice relationship: AISM:0000079 AISM:0000174 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by insect region of cuticle [Term] id: AISM:0000198 name: antennal foramen def: "The arthropod foramen of the head capsule with the antennifer and surrounds the scapus via the antenniferal-scapal conjunctiva." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} synonym: "antennal socket" EXACT [] synonym: "torulus" EXACT [] {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"antennal socket = torulus = basal socket of antenna\""} is_a: AISM:0000197 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! arthropod foramen relationship: AISM:0000079 AISM:0000019 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by head capsule relationship: AISM:0000079 AISM:0004007 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by antenniferal-scapal conjunctiva [Term] id: AISM:0000199 name: tibial carina {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-03-16"} def: "The cuticular carina that is part of the tibia and parallel to the proximal-distal axis." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2025-03-16"} is_a: AISM:0000501 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2025-03-16"} ! cuticular carina relationship: parallel_to BSPO:0000015 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2025-03-16"} ! proximal-distal axis relationship: part_of AISM:0000075 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2025-03-16"} ! tibia [Term] id: AISM:0000200 name: gonocoxa IX {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The paired sclerite of the postabdomen that is attached to the abdominal tergite IX by the abdominal tergite IX-gonocoxa IX conjunctiva and is articulated with abdominal tergite IX." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-03-19"} synonym: "second coxopodite" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Coxopodite (=valvifer, gonocoxa, gonocoxite): short basal piece of ovipositor elements of female genital segments VIII and IX.\""} synonym: "second gonocoxite" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Coxopodite (=valvifer, gonocoxa, gonocoxite): short basal piece of ovipositor elements of female genital segments VIII and IX.\""} synonym: "second valvifer" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Coxopodite (=valvifer, gonocoxa, gonocoxite): short basal piece of ovipositor elements of female genital segments VIII and IX.\""} is_a: AISM:0004301 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! gonocoxite relationship: continuous_with AISM:0000201 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite IX-gonocoxa IX conjunctiva property_value: IAO:0000589 "cuticle of gonocoxa IX" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0000201 name: abdominal tergite IX-gonocoxa IX conjunctiva def: "The conjunctiva of the postabdomen that connects the abdominal tergite IX and the gonocoxa IX." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-03-19"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: continuous_with AISM:0000200 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! gonocoxa IX relationship: continuous_with AISM:0004117 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite IX relationship: part_of AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postabdomen [Term] id: AISM:0000301 name: protarsomere {creation_date="2023-05-04", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The tarsomere that is part of the protarsus." [] {creation_date="2023-05-04", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000074 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! tarsomere relationship: part_of AISM:0004190 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! protarsus [Term] id: AISM:0000302 name: protarsomere 1 {creation_date="2023-05-04", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The protarsomere distal to the protibia and encircled by the protibio-protarsal conjunctiva." [] {creation_date="2023-05-04", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000301 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! protarsomere relationship: AISM:0000079 AISM:0004183 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! encircled by protibio-protarsal conjunctiva relationship: distal_to AISM:0000067 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! protibia [Term] id: AISM:0000303 name: protarsomere 2 {creation_date="2023-05-04", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The protarsomere that is distal to the protarsomere 1 and is encircled by the protarsomere 1-protarsomere 2 conjunctiva." [] {creation_date="2023-05-04", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000301 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! protarsomere relationship: AISM:0000079 AISM:0000319 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! encircled by protarsomere 1-protarsomere 2 conjunctiva relationship: distal_to AISM:0000302 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! protarsomere 1 [Term] id: AISM:0000304 name: protarsomere 3 {creation_date="2023-05-04", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The protarsomere that is distal to the protarsomere 2 and is encircled by the protarsomere 2-protarsomere 3 conjunctiva." [] {creation_date="2023-05-04", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000301 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! protarsomere relationship: AISM:0000079 AISM:0000320 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! encircled by protarsomere 2-protarsomere 3 conjunctiva relationship: distal_to AISM:0000303 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! protarsomere 2 [Term] id: AISM:0000305 name: protarsomere 4 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The protarsomere that is distal to the protarsomere 3 and is encircled by the protarsomere 3-protarsomere 4 conjunctiva." [] {creation_date="2023-05-04", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000301 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! protarsomere relationship: AISM:0000079 AISM:0000321 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! encircled by protarsomere 3-protarsomere 4 conjunctiva relationship: distal_to AISM:0000304 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! protarsomere 3 [Term] id: AISM:0000306 name: protarsomere 5 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The protarsomere that is distal to the protarsomere 4 and is encircled by the protarsomere 4-protarsomere 5 conjunctiva." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000301 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! protarsomere relationship: AISM:0000079 AISM:0000322 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! encircled by protarsomere 4-protarsomere 5 conjunctiva relationship: distal_to AISM:0000305 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! protarsomere 4 [Term] id: AISM:0000307 name: mesotarsomere {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The tarsomere that is part of the mesotarsus." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000074 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! tarsomere relationship: part_of AISM:0004189 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsus [Term] id: AISM:0000308 name: mesotarsomere 1 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The mesotarsomere that is distal to the mesotibia and is encircled by the mesotibio-mesotarsal conjunctiva." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000307 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsomere relationship: AISM:0000079 AISM:0004184 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by mesotibio-mesotarsal conjunctiva relationship: distal_to AISM:0000068 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotibia [Term] id: AISM:0000309 name: mesotarsomere 2 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The mesotarsomere that is distal to the mesotarsomere 1 and is encircled by the mesotarsomere 1-mesotarsomere 2 conjunctiva." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000307 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsomere relationship: AISM:0000079 AISM:0000323 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by mesotarsomere 1-mesotarsomere 2 conjunctiva relationship: distal_to AISM:0000308 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsomere 1 [Term] id: AISM:0000310 name: mesotarsomere 3 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The mesotarsomere that is distal to the mesotarsomere 2 and is encircled by the mesotarsomere 2-mesotarsomere 3 conjunctiva." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000307 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsomere relationship: AISM:0000079 AISM:0000324 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by mesotarsomere 2-mesotarsomere 3 conjunctiva relationship: distal_to AISM:0000309 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsomere 2 [Term] id: AISM:0000311 name: mesotarsomere 4 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The mesotarsomere that is distal to the mesotarsomere 3 and is encircled by the mesotarsomere 3-mesotarsomere 4 conjunctiva." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000307 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsomere relationship: AISM:0000079 AISM:0000325 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by mesotarsomere 3-mesotarsomere 4 conjunctiva relationship: distal_to AISM:0000310 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsomere 3 [Term] id: AISM:0000312 name: mesotarsomere 5 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The mesotarsomere that is distal to the mesotarsomere 4 and is encircled by the mesotarsomere 4-mesotarsomere 5 conjunctiva." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000307 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsomere relationship: AISM:0000079 AISM:0000326 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by mesotarsomere 4-mesotarsomere 5 conjunctiva relationship: distal_to AISM:0000311 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsomere 4 [Term] id: AISM:0000313 name: metatarsomere {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The tarsomere that is part of the metatarsus." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000074 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! tarsomere relationship: part_of AISM:0004188 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsus [Term] id: AISM:0000314 name: metatarsomere 1 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The metatarsomere that is distal to the metatibia and is encircled by the metatibio-metatarsal conjunctiva." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000313 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsomere relationship: AISM:0000079 AISM:0004185 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by metatibio-metatarsal conjunctiva relationship: distal_to AISM:0000069 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatibia [Term] id: AISM:0000315 name: metatarsomere 2 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The metatarsomere that is distal to the metatarsomere 1 and is encircled by the metatarsomere 1-metatarsomere 2 conjunctiva." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000313 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsomere relationship: AISM:0000079 AISM:0000327 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by metatarsomere 1-metatarsomere 2 conjunctiva relationship: distal_to AISM:0000314 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsomere 1 [Term] id: AISM:0000316 name: metatarsomere 3 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The metatarsomere that is distal to the metatarsomere 2 and is encircled by the metatarsomere 2-metatarsomere 3 conjunctiva." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000313 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsomere relationship: AISM:0000079 AISM:0000328 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by metatarsomere 2-metatarsomere 3 conjunctiva relationship: distal_to AISM:0000315 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsomere 2 [Term] id: AISM:0000317 name: metatarsomere 4 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The metatarsomere that is distal to the metatarsomere 3 and is encircled by the metatarsomere 3-metatarsomere 4 conjunctiva." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000313 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsomere relationship: AISM:0000079 AISM:0000329 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by metatarsomere 3-metatarsomere 4 conjunctiva relationship: distal_to AISM:0000316 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsomere 3 [Term] id: AISM:0000318 name: metatarsomere 5 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The metatarsomere that is distal to the metatarsomere 4 and is encircled by the metatarsomere 4-metatarsomere 5 conjunctiva." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000313 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsomere relationship: AISM:0000079 AISM:0000330 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by metatarsomere 4-metatarsomere 5 conjunctiva relationship: distal_to AISM:0000317 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsomere 4 [Term] id: AISM:0000319 name: protarsomere 1-protarsomere 2 conjunctiva {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The conjunctiva that is part of the protarsus, is encircled by protarsomere 2 and encircles protarsomere 2." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva relationship: AISM:0000078 AISM:0000303 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles protarsomere 2 relationship: AISM:0000079 AISM:0000302 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by protarsomere 1 relationship: part_of AISM:0004190 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! protarsus [Term] id: AISM:0000320 name: protarsomere 2-protarsomere 3 conjunctiva {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The conjunctiva that is part of the protarsus, is encircled by protarsomere 2 and encircles protarsomere 3." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva relationship: AISM:0000078 AISM:0000304 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles protarsomere 3 relationship: AISM:0000079 AISM:0000303 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by protarsomere 2 relationship: part_of AISM:0004190 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! protarsus [Term] id: AISM:0000321 name: protarsomere 3-protarsomere 4 conjunctiva {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The conjunctiva that is part of the protarsus, is encircled by protarsomere 3 and encircles protarsomere 4." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva relationship: AISM:0000078 AISM:0000305 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles protarsomere 4 relationship: AISM:0000079 AISM:0000304 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by protarsomere 3 relationship: part_of AISM:0004190 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! protarsus [Term] id: AISM:0000322 name: protarsomere 4-protarsomere 5 conjunctiva {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The conjunctiva that is part of the protarsus, is encircled by protarsomere 4 and encircles protarsomere 5." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva relationship: AISM:0000078 AISM:0000306 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles protarsomere 5 relationship: AISM:0000079 AISM:0000305 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by protarsomere 4 relationship: part_of AISM:0004190 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! protarsus [Term] id: AISM:0000323 name: mesotarsomere 1-mesotarsomere 2 conjunctiva {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The conjunctiva that is part of the mesotarsus, is encircled by mesotarsomere 1 and encircles mesotarsomere 2." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva relationship: AISM:0000078 AISM:0000309 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles mesotarsomere 2 relationship: AISM:0000079 AISM:0000308 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by mesotarsomere 1 relationship: part_of AISM:0004189 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsus [Term] id: AISM:0000324 name: mesotarsomere 2-mesotarsomere 3 conjunctiva {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The conjunctiva that is part of the mesotarsus, is encircled by mesotarsomere 2 and encircles mesotarsomere 3." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva relationship: AISM:0000078 AISM:0000310 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles mesotarsomere 3 relationship: AISM:0000079 AISM:0000309 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by mesotarsomere 2 relationship: part_of AISM:0004189 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsus [Term] id: AISM:0000325 name: mesotarsomere 3-mesotarsomere 4 conjunctiva {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The conjunctiva that is part of the mesotarsus, is encircled by mesotarsomere 3 and encircles mesotarsomere 4." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva relationship: AISM:0000078 AISM:0000311 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles mesotarsomere 4 relationship: AISM:0000079 AISM:0000310 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by mesotarsomere 3 relationship: part_of AISM:0004189 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsus [Term] id: AISM:0000326 name: mesotarsomere 4-mesotarsomere 5 conjunctiva {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The conjunctiva that is part of the mesotarsus, is encircled by mesotarsomere 4 and encircles mesotarsomere 5." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva relationship: AISM:0000078 AISM:0000312 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles mesotarsomere 5 relationship: AISM:0000079 AISM:0000311 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by mesotarsomere 4 relationship: part_of AISM:0004189 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsus [Term] id: AISM:0000327 name: metatarsomere 1-metatarsomere 2 conjunctiva {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The conjunctiva that is part of the metatarsus, is encircled by metatarsomere 1 and encircles metatarsomere 2." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva relationship: AISM:0000078 AISM:0000315 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles metatarsomere 2 relationship: AISM:0000079 AISM:0000314 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by metatarsomere 1 relationship: part_of AISM:0004188 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsus [Term] id: AISM:0000328 name: metatarsomere 2-metatarsomere 3 conjunctiva {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The conjunctiva that is part of the metatarsus, is encircled by metatarsomere 2 and encircles metatarsomere 3." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva relationship: AISM:0000078 AISM:0000316 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles metatarsomere 3 relationship: AISM:0000079 AISM:0000315 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by metatarsomere 2 relationship: part_of AISM:0004188 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsus [Term] id: AISM:0000329 name: metatarsomere 3-metatarsomere 4 conjunctiva {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The conjunctiva that is part of the metatarsus, is encircled by metatarsomere 3 and encircles metatarsomere 4." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva relationship: AISM:0000078 AISM:0000317 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles metatarsomere 4 relationship: AISM:0000079 AISM:0000316 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by metatarsomere 3 relationship: part_of AISM:0004188 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsus [Term] id: AISM:0000330 name: metatarsomere 4-metatarsomere 5 conjunctiva {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The conjunctiva that is part of the metatarsus, is encircled by metatarsomere 4 and encircles metatarsomere 5." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva relationship: AISM:0000078 AISM:0000318 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles metatarsomere 5 relationship: AISM:0000079 AISM:0000317 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by metatarsomere 4 relationship: part_of AISM:0004188 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsus [Term] id: AISM:0000331 name: protarsus with 5 protarsomeres {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The protarsus with protarsomeres 1-5." [] {term:modified="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0004190 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! protarsus relationship: has_part AISM:0000302 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! protarsomere 1 relationship: has_part AISM:0000303 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! protarsomere 2 relationship: has_part AISM:0000304 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! protarsomere 3 relationship: has_part AISM:0000305 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! protarsomere 4 relationship: has_part AISM:0000306 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! protarsomere 5 [Term] id: AISM:0000332 name: mesotarsus with 5 mesotarsomeres {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The mesotarsus that is composed by mesotarsomeres 1-5." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0004189 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsus relationship: has_part AISM:0000308 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsomere 1 relationship: has_part AISM:0000309 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsomere 2 relationship: has_part AISM:0000310 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsomere 3 relationship: has_part AISM:0000311 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsomere 4 relationship: has_part AISM:0000312 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsomere 5 [Term] id: AISM:0000333 name: metatarsus with 5 metatarsomeres {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The metatarsus that is composed by metatarsomeres 1-5." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0004188 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsus relationship: has_part AISM:0000314 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsomere 1 relationship: has_part AISM:0000315 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsomere 2 relationship: has_part AISM:0000316 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsomere 3 relationship: has_part AISM:0000317 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsomere 4 relationship: has_part AISM:0000318 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsomere 5 [Term] id: AISM:0000334 name: flagellomere 2 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The cuticle of the flagellomere that is distal to the flagellomere 1 and is encircled by the flagellomere 1-flagellomere 2 conjunctiva." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} synonym: "antennomere 4" EXACT [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000116 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere relationship: AISM:0000079 AISM:0000344 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 1-flagellomere 2 conjunctiva relationship: distal_to AISM:0000117 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 1 [Term] id: AISM:0000335 name: flagellomere 3 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The cuticle of the flagellomere that is distal to the flagellomere 2 and is encircled by the flagellomere 2-flagellomere 3 conjunctiva." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} synonym: "antennomere 5" EXACT [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000116 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere relationship: AISM:0000079 AISM:0000343 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 2-flagellomere 3 conjunctiva relationship: distal_to AISM:0000334 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 2 [Term] id: AISM:0000336 name: flagellomere 4 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The cuticle of the flagellomere that is distal to the flagellomere 3 and is encircled by the flagellomere 3-flagellomere 4 conjunctiva." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} synonym: "antennomere 6" EXACT [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000116 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere relationship: AISM:0000079 AISM:0000345 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 3-flagellomere 4 conjunctiva relationship: distal_to AISM:0000335 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 3 [Term] id: AISM:0000337 name: flagellomere 5 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The cuticle of the flagellomere that is distal to the flagellomere 4 and is encircled by the flagellomere 4-flagellomere 5 conjunctiva." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} synonym: "antennomere 7" EXACT [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000116 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere relationship: AISM:0000079 AISM:0000346 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 4-flagellomere 5 conjunctiva relationship: distal_to AISM:0000336 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 4 [Term] id: AISM:0000338 name: flagellomere 6 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The cuticle of the flagellomere that is distal to the flagellomere 5 and is encircled by the flagellomere 5-flagellomere 6 conjunctiva." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} synonym: "antennomere 8" EXACT [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000116 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere relationship: AISM:0000079 AISM:0000347 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 5-flagellomere 6 conjunctiva relationship: distal_to AISM:0000337 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 5 [Term] id: AISM:0000339 name: flagellomere 7 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The cuticle of the flagellomere that is distal to the flagellomere 6 and is encircled by the flagellomere 6-flagellomere 7 conjunctiva." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} synonym: "antennomere 9" EXACT [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000116 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere relationship: AISM:0000079 AISM:0000348 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 6-flagellomere 7 conjunctiva relationship: distal_to AISM:0000338 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 6 [Term] id: AISM:0000340 name: flagellomere 8 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The cuticle of the flagellomere that is distal to the flagellomere 7 and is encircled by the flagellomere 7-flagellomere 8 conjunctiva." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} synonym: "antennomere 10" EXACT [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000116 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere relationship: AISM:0000079 AISM:0000349 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 7-flagellomere 8 conjunctiva relationship: distal_to AISM:0000339 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 7 [Term] id: AISM:0000341 name: flagellomere 9 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The cuticle of the flagellomere that is distal to the flagellomere 8 and is encircled by the flagellomere 8-flagellomere 9 conjunctiva." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} synonym: "antennomere 11" EXACT [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000116 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere relationship: AISM:0000079 AISM:0000350 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 8-flagellomere 9 conjunctiva relationship: distal_to AISM:0000340 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 8 [Term] id: AISM:0000342 name: flagellomere 10 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The cuticle of the flagellomere that is distal to flagellomere 9 and is encircled by the flagellomere 9-flagellomere 10 conjunctiva." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} synonym: "antennomere 12" EXACT [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000116 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere relationship: AISM:0000079 AISM:0000351 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 9-flagellomere 10 conjunctiva relationship: distal_to AISM:0000341 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 9 [Term] id: AISM:0000343 name: flagellomere 2-flagellomere 3 conjunctiva {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The conjunctiva that is part of the antenna, is encircled by the flagellomere 2 and encircles the flagellomere 3." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva relationship: AISM:0000078 AISM:0000335 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles flagellomere 3 relationship: AISM:0000079 AISM:0000334 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 2 relationship: part_of AISM:0000032 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! antenna [Term] id: AISM:0000344 name: flagellomere 1-flagellomere 2 conjunctiva {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The conjunctiva that is part of the antenna, is encircled by the flagellomere 1 and encircles the flagellomere 2." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva relationship: AISM:0000078 AISM:0000334 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles flagellomere 2 relationship: AISM:0000079 AISM:0000117 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 1 relationship: part_of AISM:0000032 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! antenna [Term] id: AISM:0000345 name: flagellomere 3-flagellomere 4 conjunctiva {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The conjunctiva that is part of the antenna, is encircled by the flagellomere 3 and encircles the flagellomere 4." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva relationship: AISM:0000078 AISM:0000336 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles flagellomere 4 relationship: AISM:0000079 AISM:0000335 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 3 relationship: part_of AISM:0000032 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! antenna [Term] id: AISM:0000346 name: flagellomere 4-flagellomere 5 conjunctiva {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The conjunctiva that is part of the antenna, is encircled by the flagellomere 4 and encircles the flagellomere 5." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva relationship: AISM:0000078 AISM:0000337 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles flagellomere 5 relationship: AISM:0000079 AISM:0000336 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 4 relationship: part_of AISM:0000032 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! antenna [Term] id: AISM:0000347 name: flagellomere 5-flagellomere 6 conjunctiva {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The conjunctiva that is part of the antenna, is encircled by the flagellomere 5 and encircles the flagellomere 6." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva relationship: AISM:0000078 AISM:0000338 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles flagellomere 6 relationship: AISM:0000079 AISM:0000337 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 5 relationship: part_of AISM:0000032 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! antenna [Term] id: AISM:0000348 name: flagellomere 6-flagellomere 7 conjunctiva {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The conjunctiva that is part of the antenna, is encircled by the flagellomere 6 and encircles the flagellomere 7." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva relationship: AISM:0000078 AISM:0000339 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles flagellomere 7 relationship: AISM:0000079 AISM:0000338 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 6 relationship: part_of AISM:0000032 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! antenna [Term] id: AISM:0000349 name: flagellomere 7-flagellomere 8 conjunctiva {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The conjunctiva that is part of the antenna, is encircled by the flagellomere 7 and encircles the flagellomere 8." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva relationship: AISM:0000078 AISM:0000340 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles flagellomere 8 relationship: AISM:0000079 AISM:0000339 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 7 relationship: part_of AISM:0000032 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! antenna [Term] id: AISM:0000350 name: flagellomere 8-flagellomere 9 conjunctiva {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The conjunctiva that is part of the antenna, is encircled by the flagellomere 8 and encircles the flagellomere 9." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva relationship: AISM:0000078 AISM:0000341 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles flagellomere 9 relationship: AISM:0000079 AISM:0000340 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 8 relationship: part_of AISM:0000032 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! antenna [Term] id: AISM:0000351 name: flagellomere 9-flagellomere 10 conjunctiva {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The conjunctiva that is part of the antenna, is encircled by the flagellomere 9 and encircles the flagellomere 10." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva relationship: AISM:0000078 AISM:0000342 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles flagellomere 10 relationship: AISM:0000079 AISM:0000341 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 9 relationship: part_of AISM:0000032 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! antenna [Term] id: AISM:0000352 name: microreticulate {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "A structural quality inhering in a bearer by virtue of the bearer's having its surface covered with microscopic cuticular grooves forming a network." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000353 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} ! reticulate relationship: has_part AISM:0000157 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} ! cuticular groove [Term] id: AISM:0000353 name: reticulate {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "A structural quality inhering in a bearer by virtue of the bearer's presenting on its surface a network of raised and interconnected wrinkles." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: PATO:0000150 {IAO:0000232="Modified 2024-02-14: moved as subclass of texture\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! texture [Term] id: AISM:0000354 name: isodiametrically microreticulate {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "A structural quality inhering in a bearer by virtue of the bearer's being microreticulate and having meshes of isometric diameter." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000352 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} ! microreticulate is_a: PATO:0001573 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} ! isometrical [Term] id: AISM:0000355 name: abdomen with 7 sternites {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The insect abdomen that has abdominal sternites 1-7 and does not have abdominal sternite 8." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000109 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! insect abdomen relationship: has_part AISM:0004100 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! abdominal sternite I relationship: has_part AISM:0004104 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! abdominal sternite II relationship: has_part AISM:0004105 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! abdominal sternite III relationship: has_part AISM:0004106 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! abdominal sternite IV relationship: has_part AISM:0004107 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! abdominal sternite V relationship: has_part AISM:0004108 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! abdominal sternite VI relationship: has_part AISM:0004109 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! abdominal sternite VII [Term] id: AISM:0000356 name: abdomen with 8 sternites {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The insect abdomen that has abdominal sternites 1-8 and does not have abdominal sternite 9." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000109 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! insect abdomen relationship: has_part AISM:0004100 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! abdominal sternite I relationship: has_part AISM:0004104 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! abdominal sternite II relationship: has_part AISM:0004105 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! abdominal sternite III relationship: has_part AISM:0004106 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! abdominal sternite IV relationship: has_part AISM:0004107 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! abdominal sternite V relationship: has_part AISM:0004108 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! abdominal sternite VI relationship: has_part AISM:0004109 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! abdominal sternite VII relationship: has_part AISM:0004110 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! abdominal sternite VIII [Term] id: AISM:0000357 name: antenna with 8 antennomeres {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The antenna that has scapus, pedicellus, and flagellomeres 1-6, and does not have flagellomere 7." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000032 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! antenna relationship: has_part AISM:0000334 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 2 relationship: has_part AISM:0000335 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 3 relationship: has_part AISM:0000336 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 4 relationship: has_part AISM:0000337 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 5 relationship: has_part AISM:0000338 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 6 [Term] id: AISM:0000358 name: antenna with 9 antennomeres {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} def: "The antenna that has scapus, pedicellus, and flagellomeres 1-7, and does not have flagellomere 8." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} is_a: AISM:0000032 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! antenna relationship: has_part AISM:0000334 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 2 relationship: has_part AISM:0000335 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 3 relationship: has_part AISM:0000336 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 4 relationship: has_part AISM:0000337 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 5 relationship: has_part AISM:0000338 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 6 relationship: has_part AISM:0000339 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 7 [Term] id: AISM:0000359 name: clypeal tooth {creation_date="2022-10-30", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The cuticular protrusion on the anterior margin of the clypeus." [] {term:modified="18-11-2023", creation_date="2023-03-28", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000407 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", term:modified="18-11-2023", creation_date="2023-03-28"} ! cuticular tooth [Term] id: AISM:0000360 name: medial clypeal tooth {creation_date="2022-10-30", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The clypeal tooth that is not bilaterally paired and located in the medial region." [] {creation_date="2022-10-30", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000359 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2022-10-30"} ! clypeal tooth relationship: located_in BSPO:0000083 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"} ! medial region [Term] id: AISM:0000361 name: lateral clypeal tooth {creation_date="2022-10-30", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The clypeal tooth that is bilaterally paired and located in the lateral region." [] {creation_date="2022-10-30", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000359 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2022-10-30"} ! clypeal tooth relationship: has_characteristic PATO:0040024 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2022-10-30"} ! bilaterally paired relationship: located_in BSPO:0000082 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"} ! lateral region [Term] id: AISM:0000362 name: lateral clypeal tooth 1 {creation_date="2022-10-30", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The lateral clypeal tooth that is lateral to the medial region." [] {creation_date="2022-10-30", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000361 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2022-10-30"} ! lateral clypeal tooth relationship: AISM:0000011 BSPO:0000083 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"} ! lateral_to medial region [Term] id: AISM:0000363 name: lateral clypeal tooth 2 {creation_date="2022-10-30", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The lateral clypeal tooth that is lateral to the lateral clypeal tooth 1." [] {creation_date="2022-10-30", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000361 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2022-10-30"} ! lateral clypeal tooth relationship: AISM:0000011 AISM:0000362 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"} ! lateral_to lateral clypeal tooth 1 [Term] id: AISM:0000364 name: lateral clypeal tooth 3 {creation_date="2022-10-30", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The lateral clypeal tooth that is lateral to the lateral clypeal tooth 2." [] {creation_date="2022-10-30", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000361 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2022-10-30"} ! lateral clypeal tooth relationship: AISM:0000011 AISM:0000363 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"} ! lateral_to lateral clypeal tooth 2 [Term] id: AISM:0000365 name: tibial cuticular tooth {creation_date="2022-10-14", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The cuticular protrusion of the cuticle of tibia." [] {term:modified="18-11-2023", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"} is_a: AISM:0000407 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", term:modified="18-11-2023", creation_date="2023-03-28"} ! cuticular tooth relationship: part_of AISM:0000075 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"} ! tibia [Term] id: AISM:0000366 name: protibial cuticular tooth {creation_date="2022-10-14", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The cuticular protrusion of the cuticle of protibia." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"} is_a: AISM:0000365 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"} ! tibial cuticular tooth relationship: part_of AISM:0000067 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"} ! protibia [Term] id: AISM:0000367 name: dorsal protibial cuticular tooth {creation_date="2022-10-14", IAO:0000232="Modified and moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The protibial cuticular tooth on the posterior margin." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", term:modified="2023-05-03", creation_date="2023-03-28", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000366 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"} ! protibial cuticular tooth [Term] id: AISM:0000368 name: dorsal protibial cuticular tooth 1 {term:modified="2023-05-03", creation_date="2022-10-14", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The dorsal protibial cuticular tooth that is proximal to the distal margin of the tibia." [] {creation_date="2023-03-30", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", term:modified="2023-05-03", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000367 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"} ! dorsal protibial cuticular tooth [Term] id: AISM:0000369 name: dorsal protibial cuticular tooth 2 {term:modified="2023-05-03", creation_date="2022-10-14", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The dorsal protibial cuticular tooth that is proximal to the dorsal protibial cuticular tooth 1." [] {creation_date="2023-03-30", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", term:modified="2023-05-03", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000367 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"} ! dorsal protibial cuticular tooth relationship: proximal_to AISM:0000368 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-30"} ! dorsal protibial cuticular tooth 1 [Term] id: AISM:0000370 name: dorsal protibial cuticular tooth 3 {term:modified="2023-05-03", creation_date="2022-10-14", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The dorsal protibial cuticular tooth that is proximal to the dorsal protibial cuticular tooth 2." [] {creation_date="2023-03-30", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", term:modified="2023-05-03", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000367 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"} ! dorsal protibial cuticular tooth relationship: proximal_to AISM:0000369 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-30"} ! dorsal protibial cuticular tooth 2 [Term] id: AISM:0000371 name: dorsal protibial cuticular tooth 4 {term:modified="2023-05-03", creation_date="2022-10-14", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The dorsal protibial cuticular tooth that is proximal to the dorsal protibial cuticular tooth 3." [] {creation_date="2023-03-30", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", term:modified="2023-05-03", comment="", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000367 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"} ! dorsal protibial cuticular tooth relationship: proximal_to AISM:0000370 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-30"} ! dorsal protibial cuticular tooth 3 [Term] id: AISM:0000372 name: left paramere {IAO:0000232="Modified 2023-04-15: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-04-04"} def: "The cuticle of the paramere that is located in the left side of the body." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-04-04"} property_value: IAO:0000589 "cuticle of left paramere" xsd:string {creation_date="2023-04-15"} [Term] id: AISM:0000373 name: right paramere {IAO:0000232="Modified 2023-04-15: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-04-04"} def: "The cuticle of the paramere that is located in the right side of the body." [] {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-04-04"} property_value: IAO:0000589 "cuticle of right paramere" xsd:string {creation_date="2023-04-15"} [Term] id: AISM:0000374 name: tibial margin {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2025-03-16"} def: "The anatomical margin that is part of the tibia." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2025-03-16"} is_a: BSPO:0000678 ! distal margin [Term] id: AISM:0000375 name: anterior groove of tergite VIII {creation_date="2023-06-04", IAO:0000232="Modified and moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The cuticular groove that is parallel and distal to the proximal carina of tergite VIII." [] {creation_date="2023-06-04", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000157 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-06-04"} ! cuticular groove relationship: distal_to AISM:0000377 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-06-04"} ! proximal carina of tergite VIII relationship: parallel_to AISM:0000377 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-06-04"} ! proximal carina of tergite VIII [Term] id: AISM:0000376 name: interpunctural distance {creation_date="2023-06-04", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The distance between two cuticular punctures." [] {creation_date="2023-06-04", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} property_value: curator_notes "Edited by jgiron https://orcid.org/0000-0002-0851-6883 \n2024-05-11\nTo make it a distance as opposed to an anatomical space and change 'adjacent to' for 'characteristic of'\nMatching existing definitions e.g. http://purl.obolibrary.org/obo/AGRO_00000318\n\nFormer definition based on suggestions at https://github.com/obophenotype/uberon/issues/3188" xsd:string {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} [Term] id: AISM:0000377 name: proximal carina of tergite VIII {creation_date="2023-06-04", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The cuticular carina that is located on the proximal margin of the 8th tergite and is parallel to the left-right body axis." [] {creation_date="2023-06-04", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} synonym: "pygidium basal ridge" EXACT [] {creation_date="2023-06-04", AISM:0000171="Tarasov, S. I., & Solodovnikov, A. Y. (2011). Phylogenetic analyses reveal reliable morphological markers to classify mega‐diversity in Onthophagini dung beetles (Coleoptera: Scarabaeidae: Scarabaeinae). Cladistics, 27(5), 490-528. https://doi.org/10.1111/j.1096-0031.2011.00351.x\n \nPage 526, character 30", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000180 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-06-04"} ! tergal carina relationship: parallel_to BSPO:0000017 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-06-04"} ! left-right axis property_value: curator_notes "In Scarabaeinae, this carina (when present) is located in the proximalmost margin of the surface of the 8th tergite (pygidium) that is not covered by elytra." xsd:string {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-06-04"} [Term] id: AISM:0000378 name: granulate cuticular puncture {creation_date="2023-06-04", AISM:0000171="Orbigny, H. d’ (1913) [1913-1914]. Synopsis des Onthophagides d’Afrique. Annales de la Société entomologique de France, 82 : 1-742.\nhttps://www.biodiversitylibrary.org/page/8239919\n\n\"la ponctuation peut être râpeuse ou granuleuse, c'est-à-dire composée de points dont le bord antérieur s'élève en une aspérité irrégulière, ou en un granule arrondi qui ordinaireauent échancre plus ou moins ce bord antérieur\" p. 4", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The cuticular puncture that has a cuticular granule on its anterior margin." [] {creation_date="2023-06-04", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000524 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-06-04"} ! cuticular puncture [Term] id: AISM:0000379 name: ocellate cuticular puncture {creation_date="2023-06-04", AISM:0000171="Orbigny, H. d’ (1913) [1913-1914]. Synopsis des Onthophagides d’Afrique. Annales de la Société entomologique de France, 82 : 1-742.\n\nhttps://www.biodiversitylibrary.org/page/8239919\n\n\"... soit grands et à fond plat, ou ocellés, c'est-à-dire grands et à fond convexe, ou ombiliqués, c'est-à-dire grands, peu profonds et ayant dans l'intérieur un petit point plus profond\" p. 4", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The cuticular puncture that is flattened." [] {creation_date="2023-06-04", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} [Term] id: AISM:0000380 name: posterior carina of tergite VIII {creation_date="2023-06-04", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The cuticular carina that is located along the posterior margin of abdominal tergite VIII." [] {creation_date="2023-06-04", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} synonym: "ribordo del margine ventrale del pigidio" EXACT [] {creation_date="2023-06-04", AISM:0000171="Marchisio, R., & Zunino, M. E. (2012). Il genere Copris Müller. Tassonomia, filogenesi e note di zoogeografia (Vol. 2, pp. 1-176). world biodiversity association onlus.\n\nPage 26", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000180 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-06-04"} ! tergal carina [Term] id: AISM:0000381 name: head margin at genoclypeal sulcus {creation_date="2023-06-04", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The anatomical margin that is part of the anterior margin of the gena and of the lateral region of the posterior margin of the clypeus." [] {creation_date="2023-06-04", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: BSPO:0000006 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-06-04"} ! anatomical margin property_value: curator_notes "Corresponds with the region of the clypeal margin next to the distal end of the genoclypeal sulcus." xsd:string {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-06-04"} [Term] id: AISM:0000382 name: carina of vertex {IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-04-06", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The cuticular carina that is part of the vertex and parallel to the left-right body axis." [] {creation_date="2023-04-06", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} relationship: parallel_to BSPO:0000017 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-06-04"} ! left-right axis [Term] id: AISM:0000383 name: clypeal carina {IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-04-06", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The cuticular carina that is part of the clypeus and is parallel to the left-right body axis." [] {creation_date="2023-04-06", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} relationship: parallel_to BSPO:0000017 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-06-04"} ! left-right axis [Term] id: AISM:0000384 name: row of punctures {creation_date="2023-05-03", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "An anatomical row composed by cuticular punctures." [] {creation_date="2023-05-03", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: UBERON:0034926 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-03"} ! anatomical row relationship: has_part AISM:0000524 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-03"} ! cuticular puncture [Term] id: AISM:0000385 name: clypeal margin {creation_date="2023-05-03", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The anatomical margin of the anterior region of clypeus." [] {creation_date="2023-05-03", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} [Term] id: AISM:0000386 name: genal margin {creation_date="2023-05-03", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The anatomical margin of the lateral region of the gena." [] {creation_date="2023-05-03", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} [Term] id: AISM:0000387 name: ventral conjunctiva of paramere {AISM:0000171="Rossini, M., Grebennikov, V., Merrien, T., Miraldo, A., Viljanen, H., & Tarasov, S. (2022). Paleogene forest fragmentation and out‐of‐Africa dispersal explain radiation of the Paleotropical dung beetle tribe Epactoidini trib. nov.(Coleoptera: Scarabaeinae). Systematic Entomology, 47(4), 655-667.\nhttps://doi.org/10.1111/syen.12564\n\nFigure 2d", creation_date="2023-05-04", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The ventral region of the cuticle of paramere that has decreased thickness." [] {creation_date="2023-05-04", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} relationship: has_characteristic PATO:0000592 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! decreased thickness [Term] id: AISM:0000388 name: left ventral conjunctiva of paramere {creation_date="2023-05-08", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The ventral conjunctiva of the left paramere." [] {creation_date="2023-05-08", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000387 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! ventral conjunctiva of paramere relationship: part_of AISM:0000372 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! left paramere [Term] id: AISM:0000389 name: right ventral conjunctiva of paramere {creation_date="2023-05-04", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The ventral conjunctiva of the right paramere." [] {creation_date="2023-05-04", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000387 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! ventral conjunctiva of paramere relationship: part_of AISM:0000373 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! right paramere [Term] id: AISM:0000390 name: protibial apex adjacent to protibio-protarsal articulation {creation_date="2023-05-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The region of the cuticle part of the distal posterior region of protibia and adjacent to the protibio-protarsal articulation." [] {creation_date="2023-05-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000174 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-10"} ! insect region of cuticle relationship: adjacent_to AISM:0000391 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-10"} ! insect protibio-protarsal articulation [Term] id: AISM:0000391 name: insect protibio-protarsal articulation {creation_date="2023-05-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The articulation between the protibia and the protarsus." [] {creation_date="2023-05-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000002 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-10"} ! insect articulation [Term] id: AISM:0000392 name: parameres {creation_date="2023-05-30", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The region of the insect cuticle that has left and right parameres." [] {creation_date="2023-05-30", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000174 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! insect region of cuticle relationship: has_part AISM:0000372 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! left paramere relationship: has_part AISM:0000373 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! right paramere property_value: curator_notes "This term has been created to indicate simultaneously left and right parameres, in order to be able to use on it the qualities \"symmetrical\" and \"asymmetrical\", which are not applicable to single parameres." xsd:string {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} [Term] id: AISM:0000393 name: maxillary palpus with 4 palpomeres {creation_date="2023-05-30", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The maxillary palpus that has maxillary palpomeres I to IV but not maxillary palpomere V." [] {creation_date="2023-05-30", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000051 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! maxillary palpus relationship: has_part AISM:0002037 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! maxillary palpomere I relationship: has_part AISM:0002038 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! maxillary palpomere II relationship: has_part AISM:0002039 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! maxillary palpomere III relationship: has_part AISM:0002040 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! maxillary palpomere IV [Term] id: AISM:0000394 name: labial palpomere I {creation_date="2023-05-30", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The labial palpomere that is adjacent to the distal margin of the palpiger." [] {creation_date="2023-05-30", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000060 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! labial palpomere relationship: AISM:0000079 AISM:0004017 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! encircled by palpigero-palpal conjunctiva [Term] id: AISM:0000395 name: labial palpomere II {creation_date="2023-05-30", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The labial palpomere that is adjacent to the distal margin of the labial palpomere I." [] {creation_date="2023-05-30", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000060 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! labial palpomere [Term] id: AISM:0000396 name: labial palpomere III {creation_date="2023-05-30", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The labial palpomere that is adjacent to the distal margin of the labial palpomere II." [] {creation_date="2023-05-30", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000060 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! labial palpomere [Term] id: AISM:0000397 name: labial palpus with 3 palpomeres {creation_date="2023-05-30", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The labial palpus that has labial palpomeres I to III." [] {creation_date="2023-05-30", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000024 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! labial palpus relationship: has_part AISM:0000394 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! labial palpomere I relationship: has_part AISM:0000395 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! labial palpomere II relationship: has_part AISM:0000396 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! labial palpomere III [Term] id: AISM:0000405 name: antero-distal margin {creation_date="2023-11-17", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The anatomical margin that overlaps with the distal side and the anterior side." [] {creation_date="2023-11-17", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: BSPO:0000671 ! anterior margin is_a: BSPO:0000678 ! distal margin [Term] id: AISM:0000406 name: postero-distal margin {creation_date="2023-11-17", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The anatomical margin that overlaps with the distal side and the posterior side." [] {creation_date="2023-11-17", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: BSPO:0000672 ! posterior margin is_a: BSPO:0000678 ! distal margin [Term] id: AISM:0000407 name: cuticular tooth {creation_date="2023-11-18", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The cuticular protrusion that is located on an anatomical margin." [] {creation_date="2023-11-18", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} [Term] id: AISM:0000408 name: setigerous cuticular puncture {creation_date="2023-12-03", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The cuticular puncture that encircles a cuticular seta." [] {creation_date="2023-12-03", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} [Term] id: AISM:0000409 name: granulate setigerous cuticular puncture {creation_date="2023-12-03", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The setigerous cuticular puncture that has a cuticular granule on its anterior margin." [] {creation_date="2023-12-03", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000408 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-12-03"} ! setigerous cuticular puncture [Term] id: AISM:0000410 name: ocellate setigerous cuticular puncture {creation_date="2023-12-03", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The setigerous cuticular puncture that is flattened." [] {creation_date="2023-12-03", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} [Term] id: AISM:0000411 name: simple setigerous cuticular puncture {creation_date="2023-12-03", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The setigerous cuticular puncture that is flattened and does not have a cuticular granule." [] {creation_date="2023-12-03", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000408 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-12-03"} ! setigerous cuticular puncture [Term] id: AISM:0000412 name: cuticle with setigerous punctures {creation_date="2023-12-03", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The region of the insect cuticle that is covered by a collection of setigerous cuticular punctures." [] {creation_date="2023-12-03", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000174 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-12-03"} ! insect region of cuticle relationship: has_member AISM:0000408 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-12-03"} ! setigerous cuticular puncture relationship: has_part UBERON:0034925 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-12-03"} ! anatomical collection [Term] id: AISM:0000413 name: distal region of tergite VIII {creation_date="2025-02-21", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The region of the cuticle of tergite VIII that is posterior to the posterior carina of tergite VIII and anterior to the tergite's distal margin." [] {creation_date="2025-02-21", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000174 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-21"} ! insect region of cuticle relationship: part_of AISM:0004097 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-21"} ! abdominal tergite VIII relationship: posterior_to AISM:0000380 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-21"} ! posterior carina of tergite VIII [Term] id: AISM:0000414 name: clypeal margin between clypeal teeth 1 and 2 {creation_date="2025-02-21", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The bilaterally paired anatomical margin part of the anterior region of the clypeal margin that is lateral to lateral clypeal teeth 1 and medial to latera clypeal tooth 2." [] {creation_date="2025-02-21", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000385 ! clypeal margin relationship: AISM:0000011 AISM:0000362 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-21"} ! lateral_to lateral clypeal tooth 1 relationship: AISM:0000012 AISM:0000363 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-21"} ! medial_to lateral clypeal tooth 2 relationship: has_quality PATO:0040024 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-21"} ! bilaterally paired [Term] id: AISM:0000415 name: clypeal margin between clypeal teeth 1 {creation_date="2025-02-21", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The not bilaterally paired anatomical margin part of the of the anterior region of the clypeal margin that is adjacent to lateral clypeal tooth 1 but not adjacent to the medial clypeal tooth." [] {creation_date="2025-02-21", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000385 ! clypeal margin relationship: adjacent_to AISM:0000362 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-21"} ! lateral clypeal tooth 1 [Term] id: AISM:0000416 name: clypeal margin between clypeal tooth 1 and medial clypeal tooth {creation_date="2025-02-21", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The bilaterally paired anatomical margin part of the anterior region of the clypeal margin that is lateral to lateral clypeal tooth 1 and medial to latera clypeal tooth 2." [] {creation_date="2025-02-21", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000385 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-21"} ! clypeal margin relationship: AISM:0000011 AISM:0000362 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-21"} ! lateral_to lateral clypeal tooth 1 relationship: AISM:0000012 AISM:0000363 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-21"} ! medial_to lateral clypeal tooth 2 relationship: has_quality PATO:0040024 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-21"} ! bilaterally paired [Term] id: AISM:0000417 name: dorsal protibial margin between protibial teeth 1 and 2 {creation_date="2025-02-21", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The anatomical margin part of the dorsal protibial margin that is proximal to dorsal protibial cuticular tooth 1 and distal to dorsal protibial cuticular tooth 2." [] {creation_date="2025-02-21", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000374 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-21"} ! tibial margin relationship: distal_to AISM:0000369 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-21"} ! dorsal protibial cuticular tooth 2 relationship: proximal_to AISM:0000368 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-21"} ! dorsal protibial cuticular tooth 1 [Term] id: AISM:0000418 name: dorsal protibial margin between protibial teeth 2 and 3 {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The anatomical margin part of the dorsal protibial margin that is proximal to dorsal protibial cuticular tooth 2 and distal to dorsal protibial cuticular tooth 3." [] {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000374 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! tibial margin relationship: distal_to AISM:0000370 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! dorsal protibial cuticular tooth 3 relationship: proximal_to AISM:0000369 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! dorsal protibial cuticular tooth 2 [Term] id: AISM:0000419 name: dorsal protibial margin between protibial teeth 3 and 4 {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The anatomical margin part of the dorsal protibial margin that is proximal to dorsal protibial cuticular tooth 3 and distal to dorsal protibial cuticular tooth 4." [] {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000374 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! tibial margin relationship: distal_to AISM:0000371 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! dorsal protibial cuticular tooth 4 relationship: proximal_to AISM:0000370 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! dorsal protibial cuticular tooth 3 [Term] id: AISM:0000420 name: dorsal protibial margin proximal to protibial tooth 4 {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The anatomical margin part of the dorsal protibial margin that is proximal to dorsal protibial cuticular tooth 4 and distal to the profemoro-protibial conjunctiva." [] {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000374 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! tibial margin relationship: distal_to AISM:0004179 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! profemoro-protibial conjunctiva relationship: proximal_to AISM:0000371 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! dorsal protibial cuticular tooth 4 [Term] id: AISM:0000421 name: dorsal protibial margin between protibial spur and protibial tooth 1 {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The anatomical margin part of the dorsal protibial margin that is proximal to the protibial spur and distal to the dorsal protibial cuticular tooth 1." [] {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000374 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! tibial margin relationship: distal_to AISM:0000368 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! dorsal protibial cuticular tooth 1 relationship: proximal_to AISM:0000371 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! dorsal protibial cuticular tooth 4 [Term] id: AISM:0000422 name: protibial spur {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The cuticular spur that is encircled by the protibio-protarsal spur conjunctiva." [] {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000181 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! tibial spur relationship: AISM:0000079 AISM:0000423 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! encircled by protibio-protibial spur conjunctiva [Term] id: AISM:0000423 name: protibio-protibial spur conjunctiva {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The conjunctiva that enricles the protibial spur and is encircled by the protibia." [] {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! conjunctiva relationship: AISM:0000078 AISM:0000422 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! encircles protibial spur relationship: AISM:0000079 AISM:0000067 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! encircled by protibia [Term] id: AISM:0000424 name: mesotibial carina {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The tibial carina that is part of the mesotibia." [] {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000199 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! tibial carina relationship: part_of AISM:0000068 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! mesotibia [Term] id: AISM:0000425 name: metatibial carina {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The tibial carina that is part of the metatibia." [] {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000199 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! tibial carina relationship: part_of AISM:0000069 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! metatibia [Term] id: AISM:0000426 name: mesotibial posteroventral carina {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The mesotibial carina that is located in the postero-ventral region of the mesotibia." [] {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000424 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! mesotibial carina [Term] id: AISM:0000427 name: mesotibial anteroventral carina {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The mesotibial carina that is located in the antero-ventral region of the mesotibia." [] {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000424 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! mesotibial carina [Term] id: AISM:0000428 name: mesotibial anterodorsal carina {creation_date="2025-03-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The mesotibial carina that is located in the antero-dorsal region of the mesotibia." [] {creation_date="2025-03-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000424 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-10"} ! mesotibial carina [Term] id: AISM:0000429 name: mesotibial posterodorsal carina {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The mesotibial carina that is located in the postero-dorsal region of the mesotibia." [] {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000424 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! mesotibial carina [Term] id: AISM:0000430 name: metatibial posteroventral carina {creation_date="2025-03-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The mesotibial carina that is located in the antero-dorsal region of the mesotibia." [] {creation_date="2025-03-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000425 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-10"} ! metatibial carina [Term] id: AISM:0000431 name: metatibial anteroventral carina {creation_date="2025-03-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The metatibial carina that is located in the postero-ventral region of the metatibia." [] {creation_date="2025-03-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000425 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-10"} ! metatibial carina [Term] id: AISM:0000432 name: metatibial anterodorsal carina {creation_date="2025-03-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The metatibial carina that is located in the antero-dorsal region of the metatibia." [] {creation_date="2025-03-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000425 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-10"} ! metatibial carina [Term] id: AISM:0000433 name: metatibial posterodorsal carina {creation_date="2025-03-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The metatibial carina that is located in the postero-dorsal region of the metatibia." [] {creation_date="2025-03-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000425 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-10"} ! metatibial carina [Term] id: AISM:0000434 name: mesotibial spur {creation_date="2025-03-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The cuticular spur encircled by the mesotibio-mesotibial spur conjunctiva." [] {creation_date="2025-03-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000181 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-10"} ! tibial spur relationship: AISM:0000079 AISM:0000436 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-10"} ! encircled by mesotibio-mesotibial spur conjunctiva [Term] id: AISM:0000435 name: metatibial spur {creation_date="2025-03-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The cuticular spur encircled by the metatibio-metatibial spur conjunctiva." [] {creation_date="2025-03-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000181 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-10"} ! tibial spur relationship: AISM:0000079 AISM:0000437 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-10"} ! encircled by metatibio-metatibial spur conjunctiva [Term] id: AISM:0000436 name: mesotibio-mesotibial spur conjunctiva {creation_date="2025-03-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The conjunctiva that enricles the mesotibial spur and is encircled by the mesotibia." [] {creation_date="2025-02-27", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! conjunctiva relationship: AISM:0000078 AISM:0000434 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! encircles mesotibial spur relationship: AISM:0000079 AISM:0000068 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-02-27"} ! encircled by mesotibia [Term] id: AISM:0000437 name: metatibio-metatibial spur conjunctiva {creation_date="2025-03-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The conjunctiva that enricles the metatibial spur and is encircled by the metatibia." [] {creation_date="2025-03-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000004 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-10"} ! conjunctiva relationship: AISM:0000078 AISM:0000435 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-10"} ! encircles metatibial spur relationship: AISM:0000079 AISM:0000069 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-10"} ! encircled by metatibia [Term] id: AISM:0000438 name: line connecting anterior margins of eyes {creation_date="2025-03-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The anatomical line parallel to the left-right body axis that is adjacent to the anterior margins of the eyes." [] {creation_date="2025-03-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} relationship: parallel_to BSPO:0000017 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-10"} ! left-right axis [Term] id: AISM:0000439 name: line connecting posterior margins of eyes {creation_date="2025-03-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The anatomical line parallel to the left-right body axis that is adjacent to the posterior margins of the eyes." [] {creation_date="2025-03-10", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} relationship: parallel_to BSPO:0000017 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-10"} ! left-right axis [Term] id: AISM:0000440 name: protarsus with 4 protarsomeres {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The protarsus with protarsomeres 1-4, without protarsomere 5." [] {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0004190 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-11"} ! protarsus relationship: has_part AISM:0000302 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-11"} ! protarsomere 1 relationship: has_part AISM:0000303 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-11"} ! protarsomere 2 relationship: has_part AISM:0000304 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-11"} ! protarsomere 3 relationship: has_part AISM:0000305 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-11"} ! protarsomere 4 [Term] id: AISM:0000441 name: protibial carina {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The tibial carina that is part of the protibia." [] {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000199 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-11"} ! tibial carina relationship: part_of AISM:0000067 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-11"} ! protibia [Term] id: AISM:0000442 name: protibial anteroventral carina {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The protibial carina that is located in the antero-ventral region of the protibia." [] {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000441 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-11"} ! protibial carina [Term] id: AISM:0000443 name: protibial posteroventral carina {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The protibial carina that is located in the postero-ventral region of the protibia." [] {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000441 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-11"} ! protibial carina [Term] id: AISM:0000444 name: dorsal protibial margin proximal to protibial tooth 3 {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The anatomical margin part of the dorsal protibial margin that is proximal to dorsal protibial cuticular tooth 3 and distal to the profemoro-protibial conjunctiva." [] {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000374 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-11"} ! tibial margin relationship: distal_to AISM:0004179 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-11"} ! profemoro-protibial conjunctiva relationship: proximal_to AISM:0000370 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-11"} ! dorsal protibial cuticular tooth 3 [Term] id: AISM:0000445 name: line adjacent to mesotarsomeres 2-4 of mesotarsus with 5 mesotarsomeres {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The anatomical line parallel to the proximal-distal axis that is adjacent to: 1) the proximal margin of mesotarsomere 2 of mesotarsus with 5 mesotarsomeres; and 2) the distal margin of mesotarsomere 4 of mesotarsus with 5 mesotarsomeres." [] {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} relationship: BSPO:0001102 BSPO:0000015 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-11"} ! parallel to proximal-distal axis [Term] id: AISM:0000446 name: dorsal mesotibial spur {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The mesotibial spur that is located on the dorsal side of the tibial distal margin and is dorsal to the ventral protibial spur." [] {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} [Term] id: AISM:0000447 name: ventral mesotibial spur {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The mesotibial spur that is located on the ventral side of the tibial distal margin and is ventral to the dorsal protibial spur." [] {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} [Term] id: AISM:0000448 name: line adjacent to mesotarsomeres 2-5 of mesotarsus with 5 mesotarsomeres {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The anatomical line parallel to the proximal-distal axis that is adjacent to: 1) the proximal margin of mesotarsomere 2 of mesotarsus with 5 mesotarsomeres; and 2) the distal margin of mesotarsomere 5 of mesotarsus with 5 mesotarsomeres." [] {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} relationship: BSPO:0001102 BSPO:0000015 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-11"} ! parallel to proximal-distal axis [Term] id: AISM:0000449 name: line connecting medial margin of eyes {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The anatomical line parallel to the left-right body axis that is adjacent to the medial margins of the eyes." [] {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} relationship: parallel_to BSPO:0000017 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-11"} ! left-right axis [Term] id: AISM:0000450 name: membranous dorsodistal region of paramere {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} def: "The dorsodistal region of the cuticle of the paramere which has decreased thickness." [] {creation_date="2025-03-11", x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} is_a: AISM:0000174 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-11"} ! insect region of cuticle relationship: has_characteristic PATO:0000592 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2025-03-11"} ! decreased thickness [Term] id: AISM:0000501 name: cuticular carina {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"an elevated ridge or keel, not necessarily high or acute\"", term:modified="2021-12-10"} def: "The protrusion on a sclerite that is linear." [] {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330", creation_date="2021-05-06"} is_a: AISM:0000008 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! cuticular protrusion relationship: has_characteristic PATO:0001199 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! linear relationship: part_of AISM:0000003 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! insect sclerite [Term] id: AISM:0000523 name: dorsal postabdomen def: "Dorsal part of postabdomen." [] {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330", creation_date="2021-05-31"} is_a: AISM:0004057 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! abdominal tergite relationship: part_of AISM:0004056 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! postabdomen [Term] id: AISM:0000524 name: cuticular puncture {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"a small impression on the cuticle\"", term:modified="2021-12-10"} def: "The cuticular fovea that is small." [] {term:modified="2021-12-10", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-07-21"} is_a: AISM:0000156 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! cuticular fovea relationship: has_characteristic PATO:0000587 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! decreased size [Term] id: AISM:0000525 name: cuticular granule {term:modified="2021-12-10", AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"a little grain or a minute grainlike elevation\"."} def: "The cuticular protrusion of a sclerite that is small and convex." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-07-21"} is_a: AISM:0000008 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! cuticular protrusion relationship: has_characteristic PATO:0000587 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! decreased size relationship: part_of AISM:0000003 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! insect sclerite [Term] id: AISM:0000526 name: cuticular tubercle {term:modified="2021-12-10", AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"a small knoblike or rounded protuberance\""} def: "The cuticular protrusion of a sclerite that is rounded (circular)." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-07-21"} is_a: AISM:0000008 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! cuticular protrusion relationship: has_characteristic PATO:0000411 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! circular relationship: part_of AISM:0000003 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! insect sclerite [Term] id: AISM:0000527 name: cuticular spine {AISM:0000171="Richards AG, Richards PA (1979) The cuticular protuberances of insects. International Journal of Insect Morphology and Embryology 8: 143–157. \n\n\"Multicellular protuberances without differentiation of specialized cells [...] evaginations, non-movable\"", source="https://doi.org/10.1016/0020-7322(79)90013-8", term:modified="2021-12-10"} def: "The cuticular protrusion of a sclerite that is pointed and narrow." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-07-21"} is_a: AISM:0000008 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! cuticular protrusion relationship: has_characteristic PATO:0000599 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-06-20"} ! decreased width relationship: has_characteristic PATO:0002258 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! pointed relationship: part_of AISM:0000003 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! insect sclerite [Term] id: AISM:0000528 name: granulated cuticle {term:modified="2021-12-10", AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"covered with or made up of very small grains or granules\""} def: "The region of cuticle that bears an anatomical collection that is composed of granules." [] {term:modified="2021-12-10", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-07-21"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: has_member AISM:0000525 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! cuticular granule relationship: has_part UBERON:0034925 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! anatomical collection [Term] id: AISM:0000529 name: punctate cuticle {term:modified="2021-12-10", AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"set with fine, impressed points or punctures appearing as pin-pricks\""} def: "The region of cuticle that bears an anatomical collection that is composed of punctures." [] {term:modified="20021-12-10", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-07-21"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: has_member AISM:0000524 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! cuticular puncture relationship: has_part UBERON:0034925 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! anatomical collection [Term] id: AISM:0000530 name: setose cuticle {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"furnished or covered with setae or stiff hairs\"", term:modified="2021-12-10"} def: "The region of the cuticle that bears an anatomical collection that is composed of setae." [] {term:modified="2021-12-10", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-07-21"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: has_member AISM:0000039 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! cuticular seta relationship: has_part UBERON:0034925 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! anatomical collection [Term] id: AISM:0000531 name: conjunctival keel def: "The cuticular evagination constituted by conjunctiva that is elongated." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-11-19"} is_a: AISM:0000027 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! cuticular evagination relationship: has_characteristic PATO:0001154 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! elongated relationship: part_of AISM:0000004 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! conjunctiva [Term] id: AISM:0000532 name: conjunctival tubercle def: "The cuticular evagination constituted by conjunctiva that is circular." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-11-19"} is_a: AISM:0000027 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! cuticular evagination relationship: has_characteristic PATO:0000411 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! circular relationship: part_of AISM:0000004 {x_1.1:contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! conjunctiva [Term] id: AISM:0000534 name: conjunctival fold def: "The cuticular depression constituted by conjunctiva that is elongated." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-11-19"} is_a: AISM:0000005 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular depression relationship: has_characteristic PATO:0001154 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! elongated relationship: part_of AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva [Term] id: AISM:0002002 name: anterior tentorio-scapal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Anterior or dorsal tentorial arms\"\n\n\"Insertion: Anterior (ventral) basal margin of the scape\""} def: "The cranio-antennal muscle that is attached to the dorsal tentorial arm and the proximal margin of the scapus." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000081 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-antennal muscle relationship: attaches_to AISM:0004039 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! dorsal tentorial arm [Term] id: AISM:0002003 name: posterior tentorio-scapal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Anterior or dorsal tentorial arms\"\n\n\"Insertion: Posterior (dorsal) basal margin of the scape\""} def: "The cranio-antennal muscle that is attached to the dorsal or anterior tentorial arm and the proximo-dorsal margin of the scapus." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000081 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-antennal muscle [Term] id: AISM:0002004 name: lateral tentorio-scapal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Anterior or dorsal tentorial arms\"\n\n\"Insertion: Lateral basal margin of the scape\""} def: "The cranio-antennal muscle that extends between the dorsal or anterior tentorial arm and the proximo-lateral margin of the scapus." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000081 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-antennal muscle [Term] id: AISM:0002005 name: medial tentorio-scapal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Anterior or dorsal tentorial arms\"\n\n\"Insertion: Mesal basal margin of the scape\""} def: "The cranio-antennal muscle that is attached to the dorsal or anterior tentorial arm and the proximal margin of the scapus." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000081 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-antennal muscle relationship: attaches_to AISM:0004039 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! dorsal tentorial arm [Term] id: AISM:0002006 name: fronto-pedicellar muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Frons\"\n\n\"Insertion: Lateral edge of the pedicel\""} def: "The cranio-antennal muscle that is attached to the frons and the pedicellus." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000081 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-antennal muscle relationship: attaches_to AISM:0000115 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! pedicellus relationship: attaches_to AISM:0004020 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! frons [Term] id: AISM:0002007 name: lateral scapo-pedicellar muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Dorsal or dorsolateral wall of the scape\"\n\n\"Insertion: Lateral or dorsolateral wall of the pedicel\""} def: "The cranio-antennal muscle that is attached to the dorsal or dorsolateral regions of the scapus and the lateral or dorsolateral regions of the pedicellus." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000081 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-antennal muscle [Term] id: AISM:0002008 name: medial scapo-pedicellar muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Mesal or dorsomesal wall of the scape\"\n\n\"Insertion: Mesal, anteriomesal or anterior edge of the pedicel\""} def: "The cranio-antennal muscle that is attached to the scapus and the pedicellus." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000081 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-antennal muscle relationship: attaches_to AISM:0000113 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! scapus relationship: attaches_to AISM:0000115 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! pedicellus [Term] id: AISM:0002009 name: frontolabral muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Mesally on the frons or on the antennal base\"\n\n\"Insertion: Mesally on the outer basal wall of the labrum\""} def: "The cranio-labral muscle that is attached to the frons and the labrum." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000084 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-labral muscle relationship: attaches_to AISM:0004020 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! frons [Term] id: AISM:0002010 name: epistoepipharyngeal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Epistomal sulcus\"\n\n\"Insertion: Basal labral wall\""} def: "The cranio-labral muscle that is attached to the frontoclypeal ridge and the labrum." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000084 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-labral muscle relationship: attaches_to AISM:0004034 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! frontoclypeal ridge [Term] id: AISM:0002011 name: frontoepypharyngeal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Mesally on the frons or on the antennal base,\nusually on the same level as musculus\nfrontolabralis\"\n\n\"Insertion: Basal labral wall or tormae\""} def: "The cranio-labral muscle that is attached to the frons and the tormae." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000084 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-labral muscle relationship: attaches_to AISM:0002012 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! torma relationship: attaches_to AISM:0004020 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! frons [Term] id: AISM:0002012 name: torma {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Tormae: lateral apodemes of labral base\""} def: "The apodeme at either side of the proximal margin of the labrum." [] {creation_date="2021-04-22", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000188 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! apodeme [Term] id: AISM:0002013 name: transversal labral muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Ventral labral wall\"\n\n\"Insertion: Ventral labral wall of the other side\""} def: "The cranio-labral muscle that extends betwen the sides of the labrum." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000084 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-labral muscle [Term] id: AISM:0002014 name: internal cranio-mandibular muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Ventral, posterior, lateral and/or dorsal parts of\nthe head capsule and/or posterior and\nanterior tentorial arms\"\n\n\"Insertion: Tendon that inserts at the median edge of the\nmandible\""} def: "The cranio-mandibular muscle that is attached to the head capsule and the insect mandible." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000082 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-mandibular muscle [Term] id: AISM:0002017 name: posteroexternal cranio-mandibular muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Gena and postgena\"\n\n\"Insertion: Tendon that inserts at the lateral edge of the mandible\""} def: "The cranio-mandibular muscle that extends between the gena and the lateral margin of the insect mandible." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000082 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-mandibular muscle relationship: attaches_to AISM:0004026 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! gena [Term] id: AISM:0002018 name: anteroexternal cranio-mandibular muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Gena, below the compound eye\"\n\n\"Insertion: With a tendon on the mandible, posterior to the anterior articulation complex\""} def: "The cranio-mandibular muscle that is attached to the gena and the insect mandible." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000082 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-mandibular muscle relationship: attaches_to AISM:0004026 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! gena [Term] id: AISM:0002019 name: hypopharyngeal suspensorium {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043\n\n\"Suspensorium (=fulturae, hypopharyngeal arms, oral arms): sclerotized strengthening elements of proximal hypopharynx.\""} def: "The hypopharyngeal sclerite on the proximal region of the hypopharynx." [] {creation_date="2021-04-22", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", term:modified="2022-06-22"} synonym: "fulturae" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043"} synonym: "hypopharyngeal arms" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043"} synonym: "oral arms" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043"} is_a: AISM:0004275 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! hypopharyngeal sclerite [Term] id: AISM:0002021 name: hypopharyngeomandibular muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Small sclerite close to the loral arm\n(Thermobia), scleroticed arm that elongates\nthe loral arm (Neoptera)\"\n\n\"Insertion: Inner side of the lateral wall of the mandible\""} def: "The cranio-mandibular muscle that is attached to the suspensorium and the insect mandible." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000082 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-mandibular muscle relationship: attaches_to AISM:0002019 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! hypopharyngeal suspensorium [Term] id: AISM:0002022 name: superolateral tentorio-mandibular muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Anterior and dorsal tentorial arm\"\n\n\"Insertion: Outer basal edge of the mandibular body, between processus paratentorialis and posterior articulation\""} def: "The cranio-mandibular muscle that is attached to the dorsal tentorial arm and the proximal margin of the insect mandible." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000082 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-mandibular muscle relationship: attaches_to AISM:0004039 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! dorsal tentorial arm [Term] id: AISM:0002023 name: inferolateral tentorio-mandibular muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Anterior tentorial arm\"\n\n\"Insertion: Ventral basal margin of the mandible\""} def: "The cranio-mandibular muscle that extends between the anterior tentorial arm and the proximal-ventral margin of the insect mandible." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000082 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-mandibular muscle relationship: attaches_to AISM:0004038 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! anterior tentorial arm [Term] id: AISM:0002024 name: superomedial tentorio-mandibular muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Anterior and dorsal tentorial arm below musculus tentoriomandibularis externus dorsalis\"\n\n\"Insertion: Upper inner end of the mandible, just below the posterior mandibular condyle\""} def: "The cranio-mandibular muscle that is attached to the anterior tentorial arm and the insect mandible." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000082 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-mandibular muscle relationship: attaches_to AISM:0004038 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! anterior tentorial arm [Term] id: AISM:0002025 name: inferomedial tentorio-mandibular muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Anterior tentorial arm, below musculus tentoriomandibularis lateralis superior\"\n\n\"Insertion: Mediodorsal wall of the mandibular cavity\""} def: "The cranio-mandibular muscle that extends between the anterior tentorial arm and the dorso-medial region of the insect mandible." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000082 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-mandibular muscle relationship: attaches_to AISM:0004038 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! anterior tentorial arm [Term] id: AISM:0002026 name: insect cranio-maxillar muscle def: "The somatic muscle that is attached to the head capsule and the insect maxilla." [] {creation_date="2021-04-04", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932", term:modified="2021-12-13"} is_a: UBERON:0014895 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932", term:modified="2021-12-13"} ! somatic muscle relationship: attaches_to AISM:0000044 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect maxilla [Term] id: AISM:0002027 name: cranio-cardinal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Postgena and gena\"\n\n\"Insertion: Basal cardinal process\""} def: "The insect cranio-maxillar muscle that is attached to the gena and the cardo." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0002026 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranio-maxillar muscle relationship: attaches_to AISM:0000018 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cardo relationship: attaches_to AISM:0004026 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! gena [Term] id: AISM:0002028 name: cranio-lacinial muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Posterior part of the gena\"\n\n\"Insertion: Basal edge of lacinia\""} def: "The insect cranio-maxillar muscle that is attached to the gena and the lacinia." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0002026 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranio-maxillar muscle relationship: attaches_to AISM:0000026 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! lacinia relationship: attaches_to AISM:0004026 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! gena [Term] id: AISM:0002029 name: tentorio-cardinal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Tentorium\"\n\n\"Insertion: Distal part of the cardo, close to the carostipital\nsulcus\""} def: "The insect cranio-maxillar muscle that is attached to the tentorium and the cardo." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0002026 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranio-maxillar muscle relationship: attaches_to AISM:0000018 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cardo relationship: attaches_to AISM:0000191 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! tentorium [Term] id: AISM:0002030 name: anterior tentorio-stipital muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Tentorium\"\n\n\"Insertion: Stipital ridge\""} def: "The insect cranio-maxillar muscle that is attached to the tentorium and the stipital ridge." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0002026 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranio-maxillar muscle relationship: attaches_to AISM:0000191 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! tentorium relationship: attaches_to AISM:0002031 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! stipital ridge [Term] id: AISM:0002031 name: stipital ridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043"} def: "The ridge that is part of the stipes." [] {creation_date="2021-04-22", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000158 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cuticular ridge relationship: part_of AISM:0000111 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! stipes [Term] id: AISM:0002032 name: posterior tentorio-stipital muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Tentorium\"\n\n\"Insertion: Basally on the stipes, close to the stipitocardinal\nsuture\""} def: "The insect cranio-maxillar muscle that is attached to the tentorium and the stipes." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0002026 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranio-maxillar muscle relationship: attaches_to AISM:0000111 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! stipes relationship: attaches_to AISM:0000191 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! tentorium [Term] id: AISM:0002033 name: stipito-lacinial muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Lateral wall of the stipes, basal to the maxillary\npalpus\"\n\n\"Insertion: Basal edge of lacinia, in some cases common\ntendon with 0mx4\""} def: "The insect cranio-maxillar muscle that is attached to the stipes and the lacinia." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0002026 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranio-maxillar muscle relationship: attaches_to AISM:0000026 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! lacinia relationship: attaches_to AISM:0000111 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! stipes [Term] id: AISM:0002034 name: stipito-galeal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Lateral wall of the stipes, basal to the maxillary\npalpus\"\n\n\"Insertion: Basal edge of galea\""} def: "The insect cranio-maxillar muscle that is attached to the stipes and the galea." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0002026 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranio-maxillar muscle relationship: attaches_to AISM:0000023 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! galea relationship: attaches_to AISM:0000111 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! stipes [Term] id: AISM:0002035 name: stipito-palpal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x"} def: "The insect cranio-maxillar muscle that is attached to the stipes and the maxillary palpus." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0002026 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranio-maxillar muscle relationship: attaches_to AISM:0000051 {def="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! maxillary palpus relationship: attaches_to AISM:0000111 {def="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! stipes [Term] id: AISM:0002036 name: maxillary palpomere {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the mere that is part of the maxillary palpus." [] {term:modified="2021-12-08", creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000073 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mere relationship: part_of AISM:0000051 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! maxillary palpus property_value: IAO:0000589 "cuticle of maxillary palpomere" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0002037 name: maxillary palpomere I {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the maxillary palpomere that is attached to the distal margin of the palpiger and to the proximal margin of the maxillary palpomere II." [] {term:modified="2021-12-08", creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0002036 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! maxillary palpomere relationship: AISM:0000079 AISM:0004017 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by palpigero-palpal conjunctiva property_value: IAO:0000589 "cuticle of maxillary palpomere I" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0002038 name: maxillary palpomere II {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the maxillary palpomere that is attached to the distal margin of the maxillary palpomere I." [] {term:modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0002036 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! maxillary palpomere property_value: IAO:0000589 "cuticle of maxillary palpomere II" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0002039 name: maxillary palpomere III {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the maxillary palpomere that is attached to the distal margin of the maxillary palpomere II." [] {term:modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0002036 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! maxillary palpomere property_value: IAO:0000589 "cuticle of maxillary palpomere III" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0002040 name: maxillary palpomere IV {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the maxillary palpomere that is attached to the distal margin of the maxillary palpomere III." [] {term:modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0002036 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! maxillary palpomere property_value: IAO:0000589 "cuticle of maxillary palpomere IV" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0002041 name: maxillary palpomere V {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the maxillary palpomere that is attached to the distal margin of the maxillary palpomere IV." [] {term:modified="2021-12-08", creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0002036 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! maxillary palpomere property_value: IAO:0000589 "cuticle of maxillary palpomere V" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0002042 name: first maxillar palpopalpal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Basal edge of palpomere 1\"\n\n\"Insertion: Basal edge of palpomere 2\""} def: "The insect cranio-maxillar muscle that is attached to the first maxillar palpomere and the second maxillar palpomere." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0002026 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranio-maxillar muscle relationship: attaches_to AISM:0002037 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! maxillary palpomere I relationship: attaches_to AISM:0002038 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! maxillary palpomere II [Term] id: AISM:0002043 name: second maxillar palpopalpal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Mesal edge of palpomere 2\"\n\n\"Insertion: Mesal edge of palpomere 3\""} def: "The insect cranio-maxillar muscle that is attached to the second maxillar palpomere and the third maxillar palpomere." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0002026 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranio-maxillar muscle relationship: attaches_to AISM:0002038 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! maxillary palpomere II relationship: attaches_to AISM:0002039 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! maxillary palpomere III [Term] id: AISM:0002044 name: third maxillar palpopalpal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Basal edge of palpomere 3\"\n\n\"Insertion: Basal edge of palpomere 4\""} def: "The insect cranio-maxillar muscle that is attached to the third maxillar palpomere and the fourth maxillar palpomere." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0002026 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranio-maxillar muscle relationship: attaches_to AISM:0002039 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! maxillary palpomere III relationship: attaches_to AISM:0002040 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! maxillary palpomere IV [Term] id: AISM:0002045 name: fourth maxillar palpopalpal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Mesal edge of palpomere 4\"\n\n\"Insertion: Mesal edge of palpomere 5\""} def: "The insect cranio-maxillar muscle that is attached to the fourth maxillar palpomere and the fifth maxillar palpomere." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0002026 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranio-maxillar muscle relationship: attaches_to AISM:0002040 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! maxillary palpomere IV relationship: attaches_to AISM:0002041 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! maxillary palpomere V [Term] id: AISM:0002047 name: postoccipitoglossal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Postoccipital phragma\"\n\n\"Insertion: glossa\""} def: "The cranio-labial muscle that is attached to the postoccipital phragma and the glossa." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000083 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-labial muscle relationship: attaches_to AISM:0000049 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! glossa relationship: attaches_to AISM:0002049 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! postoccipital phragma [Term] id: AISM:0002048 name: phragma {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043\n\n\"Phragma: large, ridge-shaped internal apodeme.\"\n\n\"Phragma (=antecosta): dorsal thoracic transverse ridge, attachment site of dorsal longitudinal indirect flight muscles.\" (p. 121)"} def: "The internal apodeme that is continuous with the cuticle of the notum and is attached to a dorsal longitudinal muscle." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000188 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! apodeme is_a: UBERON:0000061 ! anatomical structure relationship: attaches_to AISM:0002066 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! dorsal longitudinal thoracic muscle relationship: continuous_with AISM:0004128 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! notum relationship: continuous_with UBERON:0001002 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cuticle [Term] id: AISM:0002049 name: postoccipital phragma {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x"} def: "The phragma that is continuous with the postocciput." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0002048 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! phragma relationship: continuous_with AISM:0004045 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postocciput [Term] id: AISM:0002050 name: postoccipitopremental muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Postoccipital phragma, laterad to musculus\npostoccipitoparaglossalis\"\n\n\"Insertion: Posteriolateral angle of the prementum\""} def: "The cranio-labial muscle that is attached to the postoccipital phragma and the prementum." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000083 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-labial muscle relationship: attaches_to AISM:0000057 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! prementum relationship: attaches_to AISM:0002049 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! postoccipital phragma [Term] id: AISM:0002051 name: tentorio-premental muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Posterior tentorial arms, cranium\"\n\n\"Insertion: Laterobasal edge of prementum\""} def: "The cranio-labial muscle that is attached to the posterior tentorial arm and the prementum." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000083 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-labial muscle relationship: attaches_to AISM:0000057 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! prementum relationship: attaches_to AISM:0004037 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! posterior tentorial arm [Term] id: AISM:0002052 name: tentorio-paraglossal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Posterior tentorial arms, postoccipital ridge or\ncranium\"\n\n\"Insertion: Paraglossa, close to the labial palp\""} def: "The cranio-labial muscle that is attached to the posterior tentorial arm and the paraglossa." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000083 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-labial muscle relationship: attaches_to AISM:0000050 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! paraglossa relationship: attaches_to AISM:0004037 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! posterior tentorial arm [Term] id: AISM:0002053 name: submentopremental muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Mediobasal part of submentum or gula\"\n\n\"Insertion: Mediobasal edge of prementum, close to the gales\""} def: "The cranio-labial muscle that is attached to the submentum and the prementum." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000083 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-labial muscle relationship: attaches_to AISM:0000057 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! prementum relationship: attaches_to AISM:0004005 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! submentum [Term] id: AISM:0002054 name: submentomental muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: submentum\"\n\n\"Insertion: mentum\""} def: "The cranio-labial muscle that is attached to the submentum and the mentum." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000083 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-labial muscle relationship: attaches_to AISM:0004004 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect mentum relationship: attaches_to AISM:0004005 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! submentum [Term] id: AISM:0002055 name: premento-paraglossal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Mesal on the basal edge of the prementum\"\n\n\"Insertion: Dorsobasal edge of paraglossa\""} def: "The cranio-labial muscle that is attached to the prementum and the paraglossa." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000083 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-labial muscle relationship: attaches_to AISM:0000050 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! paraglossa relationship: attaches_to AISM:0000057 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! prementum [Term] id: AISM:0002056 name: premento-glossal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Mesally on the prementum\"\n\n\"Insertion: Mediobasal edge of glossa\""} def: "The cranio-labial muscle that is attached to the prementum and the glossa." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000083 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-labial muscle relationship: attaches_to AISM:0000049 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! glossa relationship: attaches_to AISM:0000057 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! prementum [Term] id: AISM:0002057 name: premento-palpal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: prementum\"\n\n\"Insertion: labial palpus\""} def: "The cranio-labial muscle that is attached to the prementum and the labial palpus." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0000083 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-labial muscle relationship: attaches_to AISM:0000024 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! labial palpus relationship: attaches_to AISM:0000057 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! prementum [Term] id: AISM:0002058 name: cranio-hypopharyngeal muscle def: "The somatic muscle that is attached to the head capsule and the hypopharynx." [] {creation_date="2021-04-04", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932", term:modified="2021-12-13"} is_a: AISM:0000080 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranial muscle relationship: attaches_to AISM:0000093 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! hypopharynx [Term] id: AISM:0002059 name: fronto-oral muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Frons\"\n\n\"Insertion: Oral arms of the suspensorial sclerites\""} def: "The cranio-hypopharyngeal muscle that is attached to the frons and the suspensorium." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0002058 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-hypopharyngeal muscle relationship: attaches_to AISM:0002019 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! hypopharyngeal suspensorium relationship: attaches_to AISM:0004020 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! frons [Term] id: AISM:0002060 name: tentorio-oral muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Anterior tentorial arm, epistomal sulcus or\nfrons close to epistomal sulcus\"\n\n\"Insertion: Oral arms of the suspensorial sclerites, well\nseperated from above\""} def: "The cranio-hypopharyngeal muscle that is attached to the anterior tentorial arm and the suspensorium." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0002058 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-hypopharyngeal muscle relationship: attaches_to AISM:0002019 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! hypopharyngeal suspensorium relationship: attaches_to AISM:0004038 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! anterior tentorial arm [Term] id: AISM:0002061 name: insect cranio-tentorial muscle def: "The somatic muscle that is attached to the head capsule and the tentorium." [] {creation_date="2021-04-04", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932", term:modified="2021-12-13"} is_a: UBERON:0014895 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932", term:modified="2021-12-13"} ! somatic muscle relationship: attaches_to AISM:0000191 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! tentorium [Term] id: AISM:0002062 name: tentorio-frontal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Laterad on the anterior corpotentorium\"\n\n\"Insertion: Frons\""} def: "The insect cranio-antennal muscle that is attached to the tentorial bridge and the frons." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0002061 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranio-tentorial muscle relationship: attaches_to AISM:0004020 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! frons relationship: attaches_to AISM:0004024 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! tentorial bridge [Term] id: AISM:0002063 name: tentorio-tentorial muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Ventrolaterad on the anterior corpotentorium\"\n\n\"Insertion: Mesad on the posterior tentorium\""} def: "The insect cranio-antennal muscle that is attached to the tentorial bridge and the tentorium." [] {creation_date="2021-04-03", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0002061 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranio-tentorial muscle relationship: attaches_to AISM:0004024 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! tentorial bridge [Term] id: AISM:0002064 name: insect leg muscle def: "The somatic muscle that is part of the insect leg." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", term:modified="2021-12-13"} is_a: AISM:0002065 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect thoracic muscle relationship: part_of AISM:0000031 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect leg [Term] id: AISM:0002065 name: insect thoracic muscle def: "The somatic muscle that is part of the insect thorax." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", term:modified="2021-12-13"} is_a: UBERON:0014895 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! somatic muscle relationship: part_of AISM:0000108 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect thorax [Term] id: AISM:0002066 name: dorsal longitudinal thoracic muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003"} def: "The insect thoracic muscle that is not fan-shaped and runs along the dorsal region, parallel to the anterior-posterior axis." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0002065 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect thoracic muscle relationship: parallel_to BSPO:0000013 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! anterior-posterior axis relationship: part_of BSPO:0000079 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! dorsal region [Term] id: AISM:0002067 name: dorso-ventral thoracic muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003"} def: "The insect thoracic muscle that runs parallel to the dorsal-ventral axis." [] {creation_date="2021-04-22", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0002065 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect thoracic muscle relationship: parallel_to BSPO:0000016 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! dorsal-ventral axis [Term] id: AISM:0002068 name: tergo-pleural muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003"} def: "The insect thoracic muscle that extends between the notum (or tergum) and the pleura." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0002065 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect thoracic muscle relationship: attaches_to AISM:0004128 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! notum relationship: continuous_with AISM:0004129 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pleuron [Term] id: AISM:0002069 name: sterno-pleural muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003"} def: "The insect thoracic muscle that extends between the sternum and the pleura." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0002065 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect thoracic muscle relationship: attaches_to AISM:0004129 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pleuron relationship: attaches_to AISM:0004130 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! sternum [Term] id: AISM:0002070 name: ventral-longitudinal muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003"} def: "The insect thoracic muscle that is not fan-shaped and runs along the ventral region, parallel to the anterior-posterior axis." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0002065 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect thoracic muscle relationship: parallel_to BSPO:0000013 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! anterior-posterior axis relationship: part_of BSPO:0000084 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! ventral region [Term] id: AISM:0002071 name: prophragma-occipital muscle {def="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003\n\n\"origin: prophragma\"\n\"insertion: postocciput\""} def: "The dorsal longitudinal thoracic muscle that is attached to the prophragma and the postocciput." [] {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932", creation_date="2021-04-06"} is_a: AISM:0002066 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! dorsal longitudinal thoracic muscle relationship: attaches_to AISM:0002076 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! prophragma relationship: attaches_to AISM:0004045 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! postocciput [Term] id: AISM:0002072 name: pronoto-occipital muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003\n\n\"origin: pronotum\"\n\n\"insertion: postocciput\""} def: "The dorsal longitudinal thoracic muscle that is attached to the pronotum and the postocciput." [] {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932", creation_date="2021-04-06"} is_a: AISM:0002066 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! dorsal longitudinal thoracic muscle relationship: attaches_to AISM:0000059 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! pronotum relationship: attaches_to AISM:0004045 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! postocciput [Term] id: AISM:0002073 name: prophragma-cervical muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003\n\n\"origin: prophragma\"\n\"insertion: cervical sclerite\""} def: "The dorsal longitudinal thoracic muscle that is attached to the prophragma and the cervical sclerite." [] {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932", creation_date="2021-04-06"} is_a: AISM:0002066 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! dorsal longitudinal thoracic muscle relationship: attaches_to AISM:0002076 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! prophragma relationship: attaches_to AISM:0004141 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cervical sclerite [Term] id: AISM:0002074 name: dorsal cervico-occipital muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003\n\n\"origin: cervical sclerite\"\n\n\"insertion: postocciput\""} def: "The dorsal longitudinal thoracic muscle that is attached to the cervical sclerite and the postocciput." [] {creation_date="2021-04-04", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0002066 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! dorsal longitudinal thoracic muscle relationship: attaches_to AISM:0004045 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! postocciput relationship: attaches_to AISM:0004141 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cervical sclerite [Term] id: AISM:0002075 name: pronoto-phragmal muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003\n\n\"origin: pronotum\"\n\"insertion: prophragma\""} def: "The dorsal longitudinal thoracic muscle that is attached to the pronotum and the prophragma." [] {creation_date="2021-04-04", x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} is_a: AISM:0002066 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! dorsal longitudinal thoracic muscle relationship: attaches_to AISM:0000059 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! pronotum relationship: attaches_to AISM:0002076 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! prophragma [Term] id: AISM:0002076 name: prophragma def: "The phragma of the mesonotum that attaches to muscles attached to the pronotum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0002048 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! phragma relationship: part_of AISM:0000052 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! mesonotum [Term] id: AISM:0002078 name: anterior cervico-occipital muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003\n\n\"The dorsoventral muscle that arises from dorsolateral postocciput and inserts on anterior tip of first lateral cervical sclerite.\""} def: "The dorsoventral thoracic muscle of the prothorax that is attached to the anterior margin of a cervical sclerite and the dorso-lateral region of the postocciput." [] {creation_date="2021-04-22", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0002067 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! dorso-ventral thoracic muscle relationship: part_of AISM:0004125 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! prothorax [Term] id: AISM:0002079 name: anterior pronoto-cervical muscle {def="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003\n\n\"The dorsoventral muscle that arises from anterolateral pronotum and inserts on atypically on middle region of anterior propleural sclerite.\""} def: "The dorsoventral thoracic muscle that extends between the antero-lateral region of the pronotum and the medial region of the propleuron." [] {creation_date="2021-04-22", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0002067 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! dorso-ventral thoracic muscle [Term] id: AISM:0002080 name: prophragma-tentorial muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003"} def: "The dorsoventral thoracic muscle that extends between the tentorium and the prophragma." [] {creation_date="2021-04-22", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0002067 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! dorso-ventral thoracic muscle relationship: attaches_to AISM:0000191 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tentorium relationship: attaches_to AISM:0002076 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prophragma [Term] id: AISM:0002081 name: profurca-prophragmal muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003\n\n\"The dorsoventral muscle that arises from posterior face of proximal profurcal arm and inserts on lateral prophragma.\""} def: "The dorsoventral thoracic muscle that extends between the profurca and the lateral region of the prophragma." [] {creation_date="2021-04-22", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0002067 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! dorso-ventral thoracic muscle relationship: attaches_to AISM:0000143 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! profurca [Term] id: AISM:0002082 name: profurca-occipital muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003"} def: "The dorsoventral thoracic muscle that extends between the posterior region (occipital region) of the head capsule and the profurca." [] {creation_date="2021-04-22", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0002067 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! dorso-ventral thoracic muscle relationship: attaches_to AISM:0000143 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! profurca [Term] id: AISM:0002083 name: prophragma-mesophragmal muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003\n\n\"The dorsal longitudinal muscle that arises from median prophragma and inserts on median mesophragma.\""} def: "The dorsal longitudinal thoracic muscle that extends between the medial region of the prophragma and the medial region of the mesophragma." [] {creation_date="2021-04-22", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0002066 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! dorsal longitudinal thoracic muscle [Term] id: AISM:0002084 name: profurca-mesonotal muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003"} def: "The dorsoventral thoracic muscle that extends between the profurca and the mesonotum." [] {creation_date="2021-04-22", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0002067 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! dorso-ventral thoracic muscle relationship: attaches_to AISM:0000052 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesonotum relationship: attaches_to AISM:0000143 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! profurca [Term] id: AISM:0002085 name: insect abdominal muscle def: "The somatic muscle that is part of the insect abdomen." [] {creation_date="2021-04-22", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: UBERON:0014895 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932", term:modified="2021-12-13"} ! somatic muscle relationship: part_of AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen [Term] id: AISM:0002086 name: lateral abdominal muscle {AISM:0000171="Klug, R., & Bradler, S. (2006). The pregenital abdominal musculature in phasmids and its implications for the basal phylogeny of Phasmatodea (Insecta: Polyneoptera). \nOrganisms Diversity & Evolution, 6(3), 171-184.\n\nhttps://doi.org/10.1016/j.ode.2005.08.004"} def: "The insect abdominal muscle that runs along the lateral region, parallel to the dorsal-ventral axis." [] {creation_date="2021-04-22", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0002085 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect abdominal muscle relationship: parallel_to BSPO:0000016 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! dorsal-ventral axis relationship: part_of BSPO:0000082 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! lateral region [Term] id: AISM:0002087 name: ventral longitudinal abdominal muscle {AISM:0000171="Klug, R., & Bradler, S. (2006). The pregenital abdominal musculature in phasmids and its implications for the basal phylogeny of Phasmatodea (Insecta: Polyneoptera). \nOrganisms Diversity & Evolution, 6(3), 171-184.\n\nhttps://doi.org/10.1016/j.ode.2005.08.004"} def: "The insect abdominal muscle that runs along the ventral region, parallel to the anterior-posterior axis." [] {creation_date="2021-04-22", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0002085 {x_1.1:contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect abdominal muscle relationship: parallel_to BSPO:0000013 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anterior-posterior axis relationship: part_of BSPO:0000084 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! ventral region [Term] id: AISM:0002088 name: dorsal longitudinal abdominal muscle {AISM:0000171="Klug, R., & Bradler, S. (2006). The pregenital abdominal musculature in phasmids and its implications for the basal phylogeny of Phasmatodea (Insecta: Polyneoptera). \nOrganisms Diversity & Evolution, 6(3), 171-184.\n\nhttps://doi.org/10.1016/j.ode.2005.08.004"} def: "The insect abdominal muscle that runs along the dorsal region, parallel to the anterior-posterior axis." [] {creation_date="2021-04-22", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0002085 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdominal muscle relationship: parallel_to BSPO:0000013 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anterior-posterior axis relationship: part_of BSPO:0000079 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! dorsal region [Term] id: AISM:0004001 name: palpifer {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043\n\n\"Palpifer: small separate element of stipes, bears the maxillary palp.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The sclerite of the insect maxilla that is attached to the cuticle of stipes by the stipito-palpiferal conjunctiva and to the cuticle of maxillary palpus by the palpifero-palpal conjunctiva." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-17"} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: adjacent_to AISM:0000051 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! maxillary palpus relationship: adjacent_to AISM:0000111 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! stipes relationship: continuous_with AISM:0004010 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! stipito-palpiferal conjunctiva relationship: continuous_with AISM:0004012 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! palpifero-palpal conjunctiva relationship: part_of AISM:0000044 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect maxilla property_value: IAO:0000589 "cuticle of palpifer" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004002 name: mental-premental conjunctiva def: "The conjunctiva of the labium that connects the mentum and the prementum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-17"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: continuous_with AISM:0000057 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prementum relationship: continuous_with AISM:0004004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect mentum relationship: part_of AISM:0000087 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labium [Term] id: AISM:0004003 name: postmentum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Postmentum: posterior main element of labium, posteriorly adjacent with foramen occipitale in hexapods without gula or hypostomal bridge; often separated into two sclerites, the anterior mentum and the posterior submentum.\""} def: "The sclerite of the cuticle of labium that is cmposed of the submentum and the mentum, which are connected by the submental-mental conjunctiva" [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-17"} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: has_part AISM:0004004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect mentum relationship: has_part AISM:0004005 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! submentum relationship: has_part AISM:0004013 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! submental-mental conjunctiva relationship: part_of AISM:0000087 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labium [Term] id: AISM:0004004 name: insect mentum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Mentum: intermediate part of labium, anterior part of postmentum; bears the prementum at its distal edge.\"", IAO:0000232="Modified 2023-01-20: to specify insect mentum.\njgiron https://orcid.org/0000-0002-0851-6883"} def: "The sclerite of the labium that is anterior to the submentum and posterior to the prementum, and attached to the prementum by the mental-premental conjunctiva." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-17"} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: adjacent_to AISM:0000057 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prementum relationship: anterior_to AISM:0004005 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! submentum relationship: continuous_with AISM:0004002 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mental-premental conjunctiva relationship: part_of AISM:0000087 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labium relationship: posterior_to AISM:0000057 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prementum [Term] id: AISM:0004005 name: submentum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Submentum: posterior part of a divided postmentum.\""} def: "The sclerite of the labium that is anteriorly attached to the mentum by the submental-mental conjunctiva." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-17"} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: continuous_with AISM:0004013 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! submental-mental conjunctiva relationship: part_of AISM:0000087 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labium relationship: posterior_to AISM:0004004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect mentum [Term] id: AISM:0004006 name: palpiger {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043\n\n\"Palpiger: small separate element of prementum, bears the labial palp.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The sclerite of the cuticle of labium that is attached to the prementum by the premental-palpigeral conjunctiva and to the cuticle of labial palpus by the palpigero-palpal conjunctiva." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-17"} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: adjacent_to AISM:0000024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labial palpus relationship: adjacent_to AISM:0000057 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prementum relationship: continuous_with AISM:0004014 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! premental-palpigeral conjunctiva relationship: continuous_with AISM:0004017 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! palpigero-palpal conjunctiva relationship: part_of AISM:0000087 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labium property_value: IAO:0000589 "cuticle of palpiger" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004007 name: antenniferal-scapal conjunctiva def: "The conjunctiva of the head capsule that connects the antennifer and the scapus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: AISM:0000078 AISM:0000113 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles scapus relationship: continuous_with AISM:0000190 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! antennifer relationship: part_of AISM:0000112 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cranio-antennal conjunctiva [Term] id: AISM:0004008 name: interflagellomeral conjunctiva def: "Is the conjunctiva of the antenna that connects a flagellomere and other flagellomere." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000102 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! ring conjunctiva relationship: AISM:0000078 AISM:0000116 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles flagellomere relationship: AISM:0000079 AISM:0000116 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by flagellomere relationship: part_of AISM:0000032 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! antenna [Term] id: AISM:0004009 name: stipito-lacinial conjunctiva def: "The conjunctiva of the insect maxilla that connects the stipes and the lacinia." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: continuous_with AISM:0000026 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! lacinia relationship: continuous_with AISM:0000111 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! stipes relationship: part_of AISM:0000044 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect maxilla [Term] id: AISM:0004010 name: stipito-palpiferal conjunctiva def: "The conjunctiva of the insect maxilla that connects the stipes and the palpifer." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: continuous_with AISM:0000111 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! stipes relationship: continuous_with AISM:0004001 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! palpifer relationship: part_of AISM:0000044 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect maxilla [Term] id: AISM:0004011 name: stipito-galeal conjunctiva def: "The conjunctiva of the insect maxilla that connects the stipes and the galea." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: continuous_with AISM:0000023 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! galea relationship: continuous_with AISM:0000111 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! stipes relationship: part_of AISM:0000044 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect maxilla [Term] id: AISM:0004012 name: palpifero-palpal conjunctiva def: "The conjunctiva of the insect maxilla that connects the palpifer and the maxillary palpus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: continuous_with AISM:0000051 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! maxillary palpus relationship: continuous_with AISM:0004001 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! palpifer relationship: part_of AISM:0000044 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect maxilla [Term] id: AISM:0004013 name: submental-mental conjunctiva def: "The conjunctiva of the labium that connects the submentum and the mentum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: continuous_with AISM:0004004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect mentum relationship: continuous_with AISM:0004005 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! submentum relationship: part_of AISM:0000087 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labium [Term] id: AISM:0004014 name: premental-palpigeral conjunctiva def: "The conjunctiva of the labium that connects the prementum and the palpiger." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: continuous_with AISM:0000057 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prementum relationship: continuous_with AISM:0004006 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! palpiger relationship: part_of AISM:0000087 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labium [Term] id: AISM:0004015 name: premental-paraglossal conjunctiva def: "The conjunctiva of the labium that connects the prementum and the paraglossa." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: continuous_with AISM:0000050 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! paraglossa relationship: continuous_with AISM:0000057 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prementum relationship: part_of AISM:0000087 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labium [Term] id: AISM:0004016 name: premental-glossal conjunctiva def: "The conjunctiva of the labium that connects the prementum and the glossa." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: continuous_with AISM:0000049 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! glossa relationship: continuous_with AISM:0000057 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prementum relationship: part_of AISM:0000087 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labium [Term] id: AISM:0004017 name: palpigero-palpal conjunctiva def: "The conjunctiva of the labium that connects the palpiger and the labial palpus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: continuous_with AISM:0000024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labial palpus relationship: continuous_with AISM:0004006 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! palpiger relationship: part_of AISM:0000087 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labium [Term] id: AISM:0004018 name: clypeo-labral conjunctiva def: "The conjunctiva of the insect maxilla that connects the clypeus and the labrum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: continuous_with AISM:0000042 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labrum relationship: continuous_with AISM:0004019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! clypeus [Term] id: AISM:0004019 name: clypeus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Clypeus: anteroventral part of head capsule; primarily separated from frons by transverse frontoclypeal strengthening ridge between anterior tentorial pits; usually bearing the labrum at its distal margin.\""} def: "The region of the head capsule that is anterior to the frons and is attached to the labrum by the clypeo-labral conjunctiva" [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: adjacent_to AISM:0000042 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labrum relationship: anterior_to AISM:0004020 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! frons relationship: continuous_with AISM:0004018 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! clypeo-labral conjunctiva relationship: part_of AISM:0000019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! head capsule [Term] id: AISM:0004020 name: frons {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Frons: frontal part of head capsule, delimited by ecdysial lines (frontal sutures); often triangular and bearing unpaired (median) ocellus.\""} def: "The region of cuticle of the head capsule that is located posterior to the clypeus and delimited by the frontal suture." [] {creation_date="2021-04-03", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: continuous_with AISM:0004029 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! frontal suture relationship: part_of AISM:0000019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! head capsule relationship: posterior_to AISM:0004019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! clypeus [Term] id: AISM:0004021 name: postoccipital ridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Postoccipital ridge: strengthening ridge enclosing the foramen occipitale dorsally and laterally; also serving as muscle attachment area.\""} def: "The ridge along the dorsal and lateral regions of the head capsule that is adjacent to the foramen occipitale." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000158 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular ridge relationship: adjacent_to AISM:0004023 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! foramen occipitale [Term] id: AISM:0004022 name: circumocular ridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Circumocular ridge: internal ridge enclosing compound eye.\""} def: "The ridge of the head capsule surrounding the eye cuticle." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"} is_a: AISM:0000158 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular ridge relationship: AISM:0000078 AISM:0000088 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles eye cuticle relationship: part_of AISM:0000019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! head capsule [Term] id: AISM:0004023 name: foramen occipitale {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Foramen occipitale (=foramen magnum): posterior opening of head capsule; divided by tentorial bridge into alaforamen and neuroforamen.\""} def: "The foramen of the head capsule that connects with the neck membrane and is divided by the tentorial bridge into alaforamen and neuroforamen." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} synonym: "occipital foramen" EXACT [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000197 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! arthropod foramen relationship: adjacent_to AISM:0004024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tentorial bridge relationship: continuous_with AISM:0000019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! head capsule relationship: continuous_with AISM:0000098 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! neck membrane relationship: has_part AISM:0004040 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! alaforamen relationship: has_part AISM:0004041 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! neuroforamen [Term] id: AISM:0004024 name: tentorial bridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Tentorial bridge (=corpotentorium): transverse element connecting posterior tentorial arms, often plate-like.\""} def: "The apophysis of the tentorium originating from each posterior tentorial arm." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} synonym: "corpotentorium" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Tentorial bridge (=corpotentorium): transverse element connecting posterior tentorial arms, often plate-like.\""} is_a: AISM:0000138 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular apophysis relationship: continuous_with AISM:0004037 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! posterior tentorial arm relationship: part_of AISM:0000191 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tentorium [Term] id: AISM:0004025 name: vertex {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Vertex: posterodorsal part of head capsule, usually medially divided by ecdysial line (coronal suture).\""} def: "The dorsal region of the head capsule that surrounds the coronal suture, and is connected laterally to the genae." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: AISM:0000078 AISM:0004030 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles coronal suture [Term] id: AISM:0004026 name: gena {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Gena: lateral region of head capsule; not separated from vertex by a ridge or suture.\""} def: "The lateral region of the head capsule, connected dorsally to the lateral regions of the vertex." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle [Term] id: AISM:0004027 name: subgena {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Subgena: narrow lateral region of head capsule, above external side of mandibular base, usually separated from gena by subgenal ridge.\""} def: "The lateral region of the head capsule that connects dorsally to the ventral side of the gena and ventrally to the mandible." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: adjacent_to AISM:0000043 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect mandible [Term] id: AISM:0004028 name: cuticular suture {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Suture: ecdysial suture, zone of weakness.\"", term:modified="2021-12-10"} def: "The region of the cuticle of the head capsule that coincides with an ecdysial line." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: part_of AISM:0000019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! head capsule relationship: RO:0002008 AISM:0004157 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! coincident with ecdysial line [Term] id: AISM:0004029 name: frontal suture {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Frontal suture: paired ecdysial sutures enclosing frons; anterior parts of epicranial suture.\""} def: "The cuticular suture that surrounds the frons and is connected to the coronal suture." [] {creation_date="2021-04-03", term:modified="2021-12-10", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004028 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular suture relationship: AISM:0000078 AISM:0004020 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles frons relationship: continuous_with AISM:0004030 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! coronal suture relationship: has_characteristic PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired [Term] id: AISM:0004030 name: coronal suture {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Coronal suture: unpaired median ecdysial sutures dividing vertex; anteriorly continuous with frontal sutures.\""} def: "The longitudinal cuticular suture that is on the vertex and is connected to the frontal suture." [] {creation_date="2021-04-03", term:modified="2021-12-10", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004028 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular suture relationship: AISM:0000079 AISM:0004025 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by vertex relationship: continuous_with AISM:0004029 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! frontal suture relationship: parallel_to BSPO:0000013 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anterior-posterior axis [Term] id: AISM:0004031 name: pleurostomal ridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n[Pleurostomal ridge: anterior section of the subgenal ridge above the mandibular base. (p. 14)]"} def: "The ridge of the head capsule comprising the posterior region of the subgenal ridge." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000158 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular ridge [Term] id: AISM:0004032 name: subgenal ridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Subgenal ridge: strengthening ridge separating gena from subgena.\""} def: "The ridge of the head capsule that separates the gena and the subgena." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000158 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular ridge relationship: adjacent_to AISM:0004026 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! gena relationship: adjacent_to AISM:0004027 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! subgena relationship: part_of AISM:0000019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! head capsule [Term] id: AISM:0004033 name: hypostomal bridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Hypostomal bridge: partial closure of foramen occipitale, formed by ventromedially adjacent extensions of lateral head capsule.\"\n[posterior section of the subgenal ridge; p. 14]"} def: "The lateral region of the head capsule that is adjacent to the foramen occipitale" [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: adjacent_to AISM:0004023 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! foramen occipitale relationship: part_of AISM:0000019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! head capsule [Term] id: AISM:0004034 name: frontoclypeal ridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Frontoclypeal (strengthening) ridge (=frontoclypeal “suture”, epistomal “suture”): internal ridge separating clypeus from frons, between anterior tentorial pits.\""} def: "The ridge of the head capsule that separates the clypeus and the frons." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000158 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular ridge relationship: adjacent_to AISM:0004019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! clypeus relationship: adjacent_to AISM:0004020 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! frons relationship: part_of AISM:0000019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! head capsule [Term] id: AISM:0004035 name: gula {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Gula: sclerite partially closing foramen occipitale, formed by sclerotized region of ventral cervical membrane.\""} def: "The sclerite on the ventral region of the head capsule that is limited laterally by the gular ridges, posteriorly by the foramen occipitale and anteriorly by the submentum." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: anterior_to AISM:0004023 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! foramen occipitale relationship: continuous_with AISM:0004036 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! gular ridge relationship: posterior_to AISM:0004005 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! submentum [Term] id: AISM:0004036 name: gular ridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Gular ridges: lateral internal ridges enclosing the gula.\""} def: "Each ridge on the ventral region of the head capsule marking the sides of the gula." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000158 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular ridge [Term] id: AISM:0004037 name: posterior tentorial arm {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Posterior tentorial arm: paired posterior element of tentorium; originates at posterior tentorial pit.\""} def: "The apophysis of the tentorium that originates from each posterior tentorial pit." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000138 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular apophysis relationship: continuous_with AISM:0000195 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! posterior tentorial pit relationship: part_of AISM:0000191 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tentorium [Term] id: AISM:0004038 name: anterior tentorial arm {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043\n\n\"Anterior tentorial arm: paired tentorial element anterior to tentorial bridge; originates at anterior tentorial pit.\""} def: "The apophysis of the tentorium that is connected to an anterior tentorial pit." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000138 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular apophysis relationship: continuous_with AISM:0000194 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anterior tentorial pit relationship: part_of AISM:0000191 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tentorium [Term] id: AISM:0004039 name: dorsal tentorial arm {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Dorsal tentorial arm: paired dorsal element of tentorium, originating at anterior arm or connecting area of anterior and posterior arm; often connected with head capsule by fibrillae.\""} def: "The apophysis of the tentorium that is connected to an anterior tentorial arm." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000138 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular apophysis relationship: continuous_with AISM:0004038 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anterior tentorial arm relationship: part_of AISM:0000191 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tentorium [Term] id: AISM:0004040 name: alaforamen {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043\n\n\"Alaforamen: part of foramen occipitale above tentorial bridge; passage of oesophagus and tracheal stems.\""} def: "The arthropod foramen that is part of the foramen occipitale and is located above the tentorial bridge." [] {creation_date="2021-04-03", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000197 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! arthropod foramen relationship: dorsal_to AISM:0004024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tentorial bridge relationship: part_of AISM:0004023 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! foramen occipitale [Term] id: AISM:0004041 name: neuroforamen {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Neuroforamen: part of foramen occipitale below tentorial bridge; passage of cervical connectives between suboesophageal complex and prothoracic ganglion.\""} def: "The arthropod foramen that is part of the foramen occipitale and located below the tentorial bridge." [] {creation_date="2021-04-03", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000197 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! arthropod foramen relationship: part_of AISM:0004023 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! foramen occipitale relationship: ventral_to AISM:0004024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tentorial bridge [Term] id: AISM:0004042 name: postgena {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Postgena: posterior genal region anterior to postoccipital ridge.\""} def: "The posterior region of the head capsule that is continuous with the posterior region of the gena and is anterior to the postoccipital ridge." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle [Term] id: AISM:0004043 name: postgenal bridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Postgenal bridge: partial closure of foramen occipital formed by postgenal extensions.\""} def: "The region of the head capsule that is continuous with the postgena and adjacent to the foramen occipitale." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: adjacent_to AISM:0004023 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! foramen occipitale relationship: continuous_with AISM:0004042 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postgena relationship: part_of AISM:0000019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! head capsule [Term] id: AISM:0004044 name: circumantennal ridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"The antennal foramen is enclosed by a circumantennal ridge, which often bears a small articulatory process, the antennifer.\""} def: "The ridge of the head capsule that encircles the antennal foramen." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000158 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular ridge relationship: AISM:0000078 AISM:0000198 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles antennal foramen relationship: part_of AISM:0000019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! head capsule [Term] id: AISM:0004045 name: postocciput {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Postocciput: posteriormost head region.\""} def: "The dorsolateral region of the head capsule that is posterior to the postoccipital ridge" [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", term:modified="2022-06-17"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: posterior_to AISM:0004021 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-17"} ! postoccipital ridge [Term] id: AISM:0004046 name: hypostoma {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Hypostoma: posterior part of subgena.\""} def: "The region of the head capsule that comprises the posterior region of the subgena." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle [Term] id: AISM:0004047 name: hypostomal ridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Hypostomal ridge: posterior part of subgenal ridge.\""} def: "The ridge composing the posterior region of the subgenal ridge." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000158 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular ridge [Term] id: AISM:0004048 name: occipital ridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Occipital ridge (=“occipital suture”): ridge on posterior head region; present in some groups, oblique and short or more or less parallel to postocciptal rigde (Orthoptera). No true segmental border.\""} def: "The ridge that runs along the posterior region of the head capsule." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} synonym: "occipital suture" EXACT [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000158 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular ridge is_a: BSPO:0000077 ! proximal region [Term] id: AISM:0004049 name: postclypeus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Postclypeus: sclerotized and pigmented proximal part of clypeus.\""} def: "The region of cuticle comprising the posterior region of the clypeus." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle [Term] id: AISM:0004050 name: anteclypeus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Anteclypeus: transparent distal part of clypeus.\""} def: "The region of the cuticle comprising the anterior region of the clypeus." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle [Term] id: AISM:0004051 name: clypeolabrum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Clypeolabrum: area comprising the fused clypeus and labrum.\""} def: "The region of the cuticle that is composed of the clypeus and the labrum." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: has_part AISM:0000042 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labrum relationship: has_part AISM:0004019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! clypeus [Term] id: AISM:0004052 name: insect compound eye {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Compound eye: paired main light sense organs; almost always composed of numerous ommatidia.\"", IAO:0000232="Modified 2023-01-09: specifying insect compound eye.\njgiron https://orcid.org/0000-0002-0851-6883"} def: "The sense organ of the insect head that is covered by the eye cuticle." [] {creation_date="2021-04-03", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000018 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! compound eye relationship: has_part AISM:0000088 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! eye cuticle relationship: part_of AISM:0000107 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect head [Term] id: AISM:0004053 name: insect ocellus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Ocellus: relatively simple median eye with single cornea lens and always lacking a crystalline cone: three are probably present in the groundplan of Insecta, but reductions occur in many groups.\"", IAO:0000232="Modified 2023-01-09: specifying insect ocellus.\njgiron https://orcid.org/0000-0002-0851-6883"} def: "The sense organ of the insect head that is covered by eye cuticle." [] {creation_date="2021-04-03", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000020 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! sense organ relationship: has_part AISM:0000088 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! eye cuticle relationship: part_of AISM:0000107 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect head [Term] id: AISM:0004054 name: laminatentoria {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"In some groups an accessory bridge is formed by medially fused internally directed processes, the laminatentoria. This feature is sometimes erroneously referred to as “perforated corpotentorium”.\""} def: "Are apophyses of the tentorium originating at each anterior tentorial arm." [] {creation_date="2021-02-24", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000138 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular apophysis relationship: continuous_with AISM:0004038 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anterior tentorial arm relationship: part_of AISM:0000191 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tentorium [Term] id: AISM:0004055 name: preabdomen {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Preabdomen (=pregenital segments): anterior abdominal segments (I–VII).\""} def: "The region of cuticle of the insect abdomen that is posteriorly connected to the postabdomen." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-05"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: part_of AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen relationship: posteriorly_connected_to AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postabdomen [Term] id: AISM:0004056 name: postabdomen {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Postabdomen: posterior segments (VIII–XI) bearing genital appendages.\""} def: "The region of cuticle of the insect abdomen that is anteriorly connected to the preabdomen." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-05"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: anteriorly_connected_to AISM:0004055 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! preabdomen relationship: part_of AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen [Term] id: AISM:0004057 name: abdominal tergite {AISM:0000171="Lawrence J, Ślipiński A (2013) 1 Australian beetles volume 1: morphology, classification and keys. CSIRO Publishing, 520 pp. \n\nhttps://www.publish.csiro.au/book/6466/\n\n\"major plate of the abdominal tergum\""} def: "The sclerite of the insect abdomen that is dorsal and medial." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} synonym: "abdominal tergum" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Tergum: plate-like dorsal sclerite of abdominal segment.\""} is_a: AISM:0000003 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite relationship: part_of AISM:0000109 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect abdomen relationship: part_of BSPO:0000079 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! dorsal region relationship: part_of BSPO:0000083 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! medial region [Term] id: AISM:0004058 name: abdominal sternite def: "The sclerite of the insect abdomen that is ventral and medial." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} synonym: "abdominal sternum" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Sternum: plate-like ventral sclerite of abdominal segment.\""} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: part_of AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen relationship: part_of BSPO:0000083 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! medial region relationship: part_of BSPO:0000084 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! ventral region [Term] id: AISM:0004059 name: pleural membrane {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Pleural membrane: lateral unsclerotized part of abdominal segments, connecting tergum and sternum; usually bearing spiracles I–VIII.\""} def: "The conjunctiva of the insect abdomen that surrounds the spiracles." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: AISM:0000078 AISM:0000135 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles insect spiracle relationship: part_of AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen [Term] id: AISM:0004060 name: epiproct {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Epiproct: unpaired dorsal element (tergum) of segment XI.\""} def: "The sclerite of the postabdomen that is attached to the posterior margin of the abdominal tergite X by the abdominal tergite X-epiproct conjunctiva." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-05"} synonym: "proctiger" EXACT [] {AISM:0000171="Lawrence J, Ślipiński A (2013) 1 Australian beetles volume 1: morphology, classification and keys. CSIRO Publishing, 520 pp. \n\nhttps://www.publish.csiro.au/book/6466/\n\n[not defined]"} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: continuous_with AISM:0004120 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! abdominal tergite X-epiproct conjunctiva relationship: continuous_with AISM:0004197 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect anus relationship: dorsal_to AISM:0004197 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect anus relationship: part_of AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postabdomen [Term] id: AISM:0004061 name: paraproct {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Paraproct: paired lateral element of segment XI.\""} def: "The paired sclerite of the insect abdomen that is attached to the lateral margin of the abdominal tergite X by the abdominal tergite X-paraproct conjunctiva." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-05"} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: adjacent_to AISM:0004197 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect anus relationship: continuous_with AISM:0004167 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite X-paraproct conjunctiva relationship: part_of AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postabdomen [Term] id: AISM:0004062 name: aedeagus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Aedeagus (penis is often used as a synonym): male copulatory organ.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticular evagination of the postabdomen that is distal and attached to the cuticle of parameres by the paramero-aedeagal conjunctiva and is connected to the endophallus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-05"} synonym: "insect penis" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Penis: main element of the male copulatory apparatus.\""} is_a: AISM:0000027 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular evagination relationship: adjacent_to AISM:0004064 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! paramere relationship: continuous_with AISM:0004063 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! endophallus relationship: continuous_with AISM:0004200 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! paramero-aedeagal conjunctiva relationship: distal_to AISM:0004064 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! paramere relationship: part_of AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postabdomen property_value: IAO:0000589 "cuticle of aedeagus" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004063 name: endophallus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Endophallus: membranous extrusible internal part of aedeagus.\""} def: "The cuticular invagination of the postabdomen that is attached distally to the gonopore and basally to the aedeagus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-05"} is_a: AISM:0000006 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular invagination relationship: adjacent_to AISM:0004062 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! aedeagus relationship: adjacent_to AISM:0004075 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! gonopore relationship: distal_to AISM:0004075 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! gonopore relationship: part_of AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postabdomen relationship: proximal_to AISM:0004062 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! aedeagus [Term] id: AISM:0004064 name: paramere {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Parameres: paired lateral parts of aedeagus.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the paired cuticular evagination of the postabdomen that is attached to the cuticle of phallobase by the phallobasal-parameral conjunctiva and to the cuticle of aedeagus by the paramero-aedeagal conjunctiva." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-05"} is_a: AISM:0000027 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular evagination relationship: adjacent_to AISM:0004062 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! aedeagus relationship: continuous_with AISM:0004200 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! paramero-aedeagal conjunctiva relationship: continuous_with AISM:0004201 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! phallobasal-parameral conjunctiva relationship: distal_to AISM:0004065 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! phallobase relationship: has_characteristic PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired relationship: part_of AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postabdomen property_value: IAO:0000589 "cuticle of paramere" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004065 name: phallobase {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Phallobase (=basal piece): part of segment IX bearing copulatory organ.\""} def: "The region of cuticle of the postabdomen that is attached to the abdominal sternite IX by the abdominal sternite IX-phallobase conjunctiva and to the paramere by the phallobasal-parameral conjunctiva." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-05"} synonym: "basal piece" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Phallobase (=basal piece): part of segment IX bearing copulatory organ.\""} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: adjacent_to AISM:0004064 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! paramere relationship: adjacent_to AISM:0004119 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite IX relationship: continuous_with AISM:0004124 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite IX-phallobase conjunctiva relationship: continuous_with AISM:0004201 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! phallobasal-parameral conjunctiva relationship: part_of AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postabdomen [Term] id: AISM:0004066 name: endophallite {AISM:0000171="Génier F (2019) Endophallites: a proposed neologism for naming the sclerotized elements of the insect endophallus (Arthropoda: Insecta). Annales de la Société entomologique de France (N.S.) 55: 482–484. \n\nhttps://doi.org/10.1080/00379271.2019.1685907 \n\n\"endophallite(s) refer to the sclerotized structures of the endophallus whether the structure be circular, flat, folded or spiniform.\""} def: "The region of cuticle of the endophallus that is thicker." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: has_characteristic PATO:0000591 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! increased thickness relationship: part_of AISM:0004063 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! endophallus [Term] id: AISM:0004067 name: bursa copulatrix {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Bursa copulatrix: evagination of the vagina, receives the copulatory organ.\""} def: "The region of the cuticle in the postabdomen that is attached to the genital chamber." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: continuous_with AISM:0004069 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! genital chamber relationship: part_of AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postabdomen [Term] id: AISM:0004068 name: gonocoxa VIII {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Coxopodite (=valvifer, gonocoxa, gonocoxite): short basal piece of ovipositor elements of female genital segments VIII and IX.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The paired sclerite of the postabdomen that is attached to the abdominal sternite VII by the abdominal sternite VII-gonocoxa conjunctiva and is articulated with abdominal tergite IX. It is attached at the base of gonostylus VIII and adjacent to the gonopore." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-05"} synonym: "first coxopodite" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Coxopodite (=valvifer, gonocoxa, gonocoxite): short basal piece of ovipositor elements of female genital segments VIII and IX.\""} synonym: "first gonocoxite" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Coxopodite (=valvifer, gonocoxa, gonocoxite): short basal piece of ovipositor elements of female genital segments VIII and IX.\""} synonym: "first valvifer" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Coxopodite (=valvifer, gonocoxa, gonocoxite): short basal piece of ovipositor elements of female genital segments VIII and IX.\""} is_a: AISM:0004301 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! gonocoxite relationship: adjacent_to AISM:0004075 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! gonopore relationship: continuous_with AISM:0004084 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite VIII-gonocoxa VIII conjunctiva property_value: IAO:0000589 "cuticle of gonocoxa VIII" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004069 name: genital chamber {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Genital chamber: cavity formed by an inflection of the body wall, receiving the common oviduct.\""} def: "The region of cuticle that is connected to the oviduct, the bursa copulatrix and the gonocoxa VIII, and is adjacent to the gonopore." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-05"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: adjacent_to AISM:0004075 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! gonopore relationship: continuous_with AISM:0004067 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bursa copulatrix relationship: continuous_with AISM:0004068 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! gonocoxa VIII relationship: continuous_with AISM:0004083 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect oviduct [Term] id: AISM:0004070 name: gonapophysis {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Gonapophysis (=valves or valvulae 1–3): distal piece of ovipositor elements of female genital segments VIII and IX, inserted on coxopodites, usually elongated.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the appendage of the abdominal sternite VIII that is part of the ovipositor." [] {term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000029 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect appendage relationship: part_of AISM:0004077 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! ovipositor relationship: part_of AISM:0004110 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite VIII property_value: IAO:0000589 "cuticle of gonapophysis" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004071 name: sensillum placodeum {IAO:0000232="Modified 2023-01-11: moved under cuticular sensilla; added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Sensillum placodeum: flat sensillum with strongly modified plate-like seta.\""} def: "The seta that is flattened." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0004304 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular sensilla relationship: has_characteristic PATO:0000407 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! flat relationship: has_part AISM:0000039 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! cuticular seta [Term] id: AISM:0004072 name: trichobothrium {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Trichobothrium: very long and fine sensillum, vibroreceptor.\""} def: "The seta that is elongated." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000039 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular seta relationship: has_characteristic PATO:0001154 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! elongated [Term] id: AISM:0004073 name: paraphyses {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Paraphyses (=titillators): paired appendages of aedeagus.\""} def: "The proximal apodemes of the aedeagus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} synonym: "titillators" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Paraphyses (=titillators): paired appendages of aedeagus.\""} is_a: AISM:0000188 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! apodeme relationship: proximal_to AISM:0004062 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! aedeagus [Term] id: AISM:0004074 name: ductus ejaculatorius {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Ductus ejaculatorius: unpaired ectodermal duct connecting vasa deferentia (i.e. vesiculae seminales) and aedeagus.\""} def: "The region of the cuticle thar is proximally attached to the gonopore." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: adjacent_to AISM:0004075 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! gonopore relationship: proximal_to AISM:0004075 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! gonopore [Term] id: AISM:0004075 name: gonopore {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Gonopore: external opening of the common oviduct.\"", creation_date="2021-03-05"} def: "The orifice in the postabdomen that marks the opening of the reproductive system." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: UBERON:0000161 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! orifice relationship: AISM:0000079 AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by postabdomen [Term] id: AISM:0004076 name: gonostylus VIII {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Gonostyli: appendages of gonocoxae (usually only on coxopodite IX)\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The region of the cuticle of the postabdomen that is paired and connected to the anterior region of the gonocoxa VIII." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-05"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: has_characteristic PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired relationship: part_of AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postabdomen property_value: IAO:0000589 "cuticle of gonostylus VIII" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004077 name: ovipositor {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Ovipositor: paired postabdominal apparatus (segments VIII and IX) primarily used for depositing eggs.\""} def: "The region of cuticle of the postabdomen that is distal to the genital chamber." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: distal_to AISM:0004069 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! genital chamber relationship: part_of AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postabdomen [Term] id: AISM:0004078 name: spermatheca {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Spermatheca (=receptaculum seminis): unpaired or paired evagination of female genital tract; storage of sperm; connected by spermathecal duct (=ductus receptaculi) with vagina or bursa copulatrix.\""} def: "The region of the cuticle that is part of the oviduct and connected to the bursa copulatrix." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: continuous_with AISM:0004067 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bursa copulatrix relationship: part_of AISM:0004083 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect oviduct [Term] id: AISM:0004079 name: spermathecal gland {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Spermathecal gland: provides nourishment for spermatozoa stored in spermatheca.\""} def: "The region of the cuticle that is part of the oviduct and attached to the spermatheca." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: continuous_with AISM:0004078 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! spermatheca relationship: part_of AISM:0004083 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect oviduct [Term] id: AISM:0004080 name: precoxal sulcus def: "The sulcus that coincides with the precoxal ridge." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} synonym: "precoxal suture" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Precoxal suture: suture separating katepisternum and preepisternum.\""} is_a: AISM:0000162 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular sulcus relationship: RO:0002008 AISM:0004162 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! coincident with precoxal ridge [Term] id: AISM:0004081 name: pleural wing process {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Fulcrum (=pleural wing process): anterodorsal apex of the pleural ridge.\""} def: "The cuticular protrusion of the pleuron that is connected lateraly to the notum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} synonym: "fulcrum" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Fulcrum (=pleural wing process): anterodorsal apex of the pleural ridge.\""} is_a: AISM:0000008 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular protrusion relationship: AISM:0000011 AISM:0004128 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! lateral_to notum relationship: part_of AISM:0004129 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pleuron [Term] id: AISM:0004082 name: metanoto-abdominal tergite I conjunctiva def: "The conjunctiva between the insect thorax and the insect abdomen that connects the posterior margin of the metanotum to the anterior margin of the abdominal tergite I." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: continuous_with AISM:0000021 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite I relationship: continuous_with AISM:0000169 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metanotum [Term] id: AISM:0004083 name: insect oviduct {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Oviduct: female genital duct; originating as paired structures from ovarioles, uniting as common (median) oviduct.\""} def: "The region of cuticle that is continuous with the genital chamber." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle is_a: UBERON:0000993 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! oviduct relationship: continuous_with AISM:0004069 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! genital chamber [Term] id: AISM:0004084 name: abdominal sternite VIII-gonocoxa VIII conjunctiva def: "The conjunctiva of the insect abdomen that joins the abdominal sternite VIII and the gonocoxa VIII." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-01-09: correct sternite VII to VIII.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: continuous_with AISM:0004068 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! gonocoxa VIII relationship: continuous_with AISM:0004110 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite VIII relationship: part_of AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen [Term] id: AISM:0004085 name: abdominal tergite II def: "Is the abdominal tergite of the preabdomen that is attached to the posterior margin of the abdominal tergite I by the abdominal tergite I-abdominal tergite II conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004057 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite relationship: anteriorly_connected_to AISM:0004086 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite I-abdominal tergite II conjunctiva relationship: part_of AISM:0004055 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! preabdomen [Term] id: AISM:0004086 name: abdominal tergite I-abdominal tergite II conjunctiva def: "The conjunctiva of the insect abdomen that connects the abdominal tergite I and the abdominal tergite II." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: continuous_with AISM:0000021 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite I relationship: continuous_with AISM:0004085 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite II relationship: part_of AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen [Term] id: AISM:0004087 name: abdominal tergite III def: "Is the abdominal tergite of the preabdomen that is attached to the posterior margin of the abdominal tergite II by the abdominal tergite II-abdominal tergite III conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004057 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite relationship: anteriorly_connected_to AISM:0004088 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite II-abdominal tergite III conjunctiva relationship: part_of AISM:0004055 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! preabdomen [Term] id: AISM:0004088 name: abdominal tergite II-abdominal tergite III conjunctiva def: "The conjunctiva of the insect abdomen that connects the abdominal tergite II and the abdominal tergite III." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: continuous_with AISM:0004085 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite II relationship: continuous_with AISM:0004087 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite III relationship: part_of AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen [Term] id: AISM:0004089 name: abdominal tergite III-abdominal tergite IV conjunctiva def: "The conjunctiva of the insect abdomen that connects the abdominal tergite III and the abdominal tergite IV." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: continuous_with AISM:0004087 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite III relationship: continuous_with AISM:0004090 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite IV relationship: part_of AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen [Term] id: AISM:0004090 name: abdominal tergite IV def: "Is the abdominal tergite of the preabdomen that is attached to the posterior margin of the abdominal tergite III by the abdominal tergite III-abdominal tergite IV conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004057 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite relationship: anteriorly_connected_to AISM:0004089 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite III-abdominal tergite IV conjunctiva relationship: part_of AISM:0004055 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! preabdomen [Term] id: AISM:0004091 name: abdominal tergite V def: "Is the abdominal tergite of the preabdomen that is attached to the posterior margin of the abdominal tergite IV by the abdominal tergite IV-abdominal tergite V conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004057 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite relationship: anteriorly_connected_to AISM:0004092 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite IV-abdominal tergite V conjunctiva relationship: part_of AISM:0004055 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! preabdomen [Term] id: AISM:0004092 name: abdominal tergite IV-abdominal tergite V conjunctiva def: "The conjunctiva of the insect abdomen that connects the abdominal tergite IV and the abdominal tergite V." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: continuous_with AISM:0004090 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite IV relationship: continuous_with AISM:0004091 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite V relationship: part_of AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen [Term] id: AISM:0004093 name: abdominal tergite VI def: "Is the abdominal tergite of the preabdomen that is attached to the posterior margin of the abdominal tergite V by the abdominal tergite V-abdominal tergite VI conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004057 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite relationship: anteriorly_connected_to AISM:0004094 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite V-abdominal tergite VI conjunctiva relationship: part_of AISM:0004055 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! preabdomen [Term] id: AISM:0004094 name: abdominal tergite V-abdominal tergite VI conjunctiva def: "The conjunctiva of the insect abdomen that connects the abdominal tergite V and the abdominal tergite VI." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: continuous_with AISM:0004091 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite V relationship: continuous_with AISM:0004093 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite VI relationship: part_of AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen [Term] id: AISM:0004095 name: abdominal tergite VII def: "Is the abdominal tergite of the preabdomen that is attached to the posterior margin of the abdominal tergite VI by the abdominal tergite VI-abdominal tergite VII conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004057 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite relationship: anteriorly_connected_to AISM:0004096 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite VI-abdominal tergite VII conjunctiva relationship: part_of AISM:0004055 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! preabdomen [Term] id: AISM:0004096 name: abdominal tergite VI-abdominal tergite VII conjunctiva def: "The conjunctiva of the insect abdomen that connects the abdominal tergite VI and the abdominal tergite VII." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: continuous_with AISM:0004093 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite VI relationship: continuous_with AISM:0004095 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite VII relationship: part_of AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen [Term] id: AISM:0004097 name: abdominal tergite VIII def: "Is the abdominal tergite of the postabdomen that is attached to the posterior margin of the abdominal tergite VII by the abdominal tergite VII-abdominal tergite VIII conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004057 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite relationship: anteriorly_connected_to AISM:0004098 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite VII-abdominal tergite VIII conjunctiva relationship: part_of AISM:0000523 ! dorsal postabdomen [Term] id: AISM:0004098 name: abdominal tergite VII-abdominal tergite VIII conjunctiva def: "The conjunctiva of the insect abdomen that connects the abdominal tergite VII and the abdominal tergite VIII." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: continuous_with AISM:0004095 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite VII relationship: continuous_with AISM:0004097 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite VIII relationship: part_of AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen [Term] id: AISM:0004099 name: laterotergite {AISM:0000171="Lawrence J, Ślipiński A (2013) 1 Australian beetles volume 1: morphology, classification and keys. CSIRO Publishing, 520 pp. \n\nhttps://www.publish.csiro.au/book/6466/\n\nadditional pair of sclerites flanking each tergite"} name: laterotergite {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Laterotergite: separate lateral portion of abdominal tergum (only few groups).\""} def: "The sclerite of the insect thorax or the insect abdomen that is on the lateral region of the notum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} synonym: "paranota" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Paranota (=laterotergites): dorsolateral tergal duplicatures.\""} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: part_of AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen [Term] id: AISM:0004100 name: abdominal sternite I def: "The abdominal sternite of the preabdomen that is attached to the posterior margin of the metasternum by the metasterno-abdominal sternite I conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004058 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite relationship: anteriorly_connected_to AISM:0004102 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metasterno-abdominal sternite I conjunctiva relationship: part_of AISM:0004055 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! preabdomen [Term] id: AISM:0004101 name: metapleuro-metasternal conjunctiva def: "The conjunctiva of the metathorax that joins the metapleura and the metasternum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: continuous_with AISM:0000119 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metapleuron relationship: continuous_with AISM:0004232 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metasternum relationship: part_of AISM:0004127 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metathorax [Term] id: AISM:0004102 name: metasterno-abdominal sternite I conjunctiva def: "The conjunctiva between the insect thorax and the insect abdomen that connects the posterior margin of the metasterum to the anterior margin of the abdominal sternite I." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: continuous_with AISM:0004100 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite I relationship: continuous_with AISM:0004101 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metapleuro-metasternal conjunctiva [Term] id: AISM:0004103 name: abdominal sternite I-abdominal sternite II conjunctiva def: "The conjunctiva of the insect abdomen that connects the abdominal sternite I and the abdominal sternite II." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: continuous_with AISM:0004100 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite I relationship: continuous_with AISM:0004104 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite II relationship: part_of AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen [Term] id: AISM:0004104 name: abdominal sternite II def: "The abdominal tergite of the preabdomen that is attached to the posterior margin of the abdominal sternite I by the abdominal sternite I-abdominal sternite II conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004058 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite relationship: anteriorly_connected_to AISM:0004103 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite I-abdominal sternite II conjunctiva relationship: part_of AISM:0004055 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! preabdomen [Term] id: AISM:0004105 name: abdominal sternite III def: "The abdominal sternite of the preabdomen that is attached to the posterior margin of the abdominal sternite II by the abdominal sternite II-abdominal sternite III conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004058 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite relationship: anteriorly_connected_to AISM:0004111 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite II-abdominal sternite III conjunctiva relationship: part_of AISM:0004055 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! preabdomen [Term] id: AISM:0004106 name: abdominal sternite IV def: "The abdominal sternite of the preabdomen that is attached to the posterior margin of the abdominal sternite III by the abdominal sternite III-abdominal sternite IV conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004058 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite relationship: anteriorly_connected_to AISM:0004112 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite III-abdominal sternite IV conjunctiva relationship: part_of AISM:0004055 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! preabdomen [Term] id: AISM:0004107 name: abdominal sternite V def: "The abdominal sternite of the preabdomen that is attached to the posterior margin of the abdominal sternite IV by the abdominal sternite IV-abdominal sternite V conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004058 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite relationship: anteriorly_connected_to AISM:0004113 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite IV-abdominal sternite V conjunctiva relationship: part_of AISM:0004055 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! preabdomen [Term] id: AISM:0004108 name: abdominal sternite VI def: "The abdominal sternite of the preabdomen that is attached to the posterior margin of the abdominal sternite V by the abdominal sternite V-abdominal sternite VI conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004058 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite relationship: anteriorly_connected_to AISM:0004114 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite V-abdominal sternite VI conjunctiva relationship: part_of AISM:0004055 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! preabdomen [Term] id: AISM:0004109 name: abdominal sternite VII def: "The abdominal sternite of the preabdomen that is attached to the posterior margin of the abdominal sternite VI by the abdominal sternite VI-abdominal sternite VII conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004058 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite relationship: anteriorly_connected_to AISM:0004115 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite VI-abdominal sternite VII conjunctiva relationship: part_of AISM:0004055 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! preabdomen [Term] id: AISM:0004110 name: abdominal sternite VIII def: "The abdominal sternite of the postabdomen that is attached to the posterior margin of the abdominal sternite VII by the abdominal sternite VII-abdominal sternite VIII conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004058 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite relationship: part_of AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postabdomen relationship: posteriorly_connected_to AISM:0004123 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite VIII-abdominal sternite IX conjunctiva [Term] id: AISM:0004111 name: abdominal sternite II-abdominal sternite III conjunctiva def: "The conjunctiva of the insect abdomen that connects the abdominal sternite II and the abdominal sternite III." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: continuous_with AISM:0004104 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite II relationship: continuous_with AISM:0004105 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite III relationship: part_of AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen [Term] id: AISM:0004112 name: abdominal sternite III-abdominal sternite IV conjunctiva def: "The conjunctiva of the insect abdomen that connects the abdominal sternite III and the abdominal sternite IV." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: continuous_with AISM:0004105 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite III relationship: continuous_with AISM:0004106 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite IV relationship: part_of AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen [Term] id: AISM:0004113 name: abdominal sternite IV-abdominal sternite V conjunctiva def: "The conjunctiva of the insect abdomen that connects the abdominal sternite IV and the abdominal sternite V." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: continuous_with AISM:0004106 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite IV relationship: continuous_with AISM:0004107 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite V relationship: part_of AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen [Term] id: AISM:0004114 name: abdominal sternite V-abdominal sternite VI conjunctiva def: "The conjunctiva of the insect abdomen that connects the abdominal sternite V and the abdominal sternite VI." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: continuous_with AISM:0004107 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite V relationship: continuous_with AISM:0004108 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite VI relationship: part_of AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen [Term] id: AISM:0004115 name: abdominal sternite VI-abdominal sternite VII conjunctiva def: "The conjunctiva of the insect abdomen that connects the abdominal sternite VI and the abdominal sternite VII." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: continuous_with AISM:0004108 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite VI relationship: continuous_with AISM:0004109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite VII relationship: part_of AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen [Term] id: AISM:0004116 name: abdominal sternite VII-abdominal sternite VIII conjunctiva def: "The conjunctiva of the insect abdomen that connects the abdominal sternite VII and the abdominal sternite VIII." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: continuous_with AISM:0004109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite VII relationship: continuous_with AISM:0004110 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite VIII relationship: part_of AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen [Term] id: AISM:0004117 name: abdominal tergite IX def: "Is the abdominal tergite of the postabdomen that is attached to the posterior margin of the abdominal tergite VIII by the abdominal tergite VIII-abdominal tergite IX conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004057 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite relationship: anteriorly_connected_to AISM:0004121 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite VIII-abdominal tergite IX conjunctiva relationship: part_of AISM:0000523 ! dorsal postabdomen [Term] id: AISM:0004118 name: abdominal tergite X def: "Is the abdominal tergite of the postabdomen that is attached to the posterior margin of the abdominal tergite IX by the abdominal tergite IX-abdominal tergite X conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004057 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite relationship: anteriorly_connected_to AISM:0004122 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite IX-abdominal tergite X conjunctiva relationship: part_of AISM:0000523 ! dorsal postabdomen [Term] id: AISM:0004119 name: abdominal sternite IX def: "The abdominal sternite of the postabdomen that is attached to the posterior margin of the abdominal sternite VIII by the abdominal sternite VIII-abdominal sternite IX conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004058 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite relationship: anteriorly_connected_to AISM:0004116 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite VII-abdominal sternite VIII conjunctiva relationship: part_of AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postabdomen [Term] id: AISM:0004120 name: abdominal tergite X-epiproct conjunctiva def: "The conjunctiva of the postabdomen that joins the abdominal tergite X and the epiproct." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: continuous_with AISM:0004060 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! epiproct relationship: continuous_with AISM:0004118 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite X relationship: part_of AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postabdomen [Term] id: AISM:0004121 name: abdominal tergite VIII-abdominal tergite IX conjunctiva def: "The conjunctiva of the insect abdomen that connects the abdominal tergite VIII and the abdominal tergite IX." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: continuous_with AISM:0004097 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite VIII relationship: continuous_with AISM:0004117 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite IX relationship: part_of AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen [Term] id: AISM:0004122 name: abdominal tergite IX-abdominal tergite X conjunctiva def: "The conjunctiva of the insect abdomen that connects the abdominal tergite IX and the abdominal tergite X." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: continuous_with AISM:0004117 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite IX relationship: continuous_with AISM:0004118 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite X relationship: part_of AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen [Term] id: AISM:0004123 name: abdominal sternite VIII-abdominal sternite IX conjunctiva def: "The conjunctiva of the insect abdomen that connects the abdominal sternite VIII and the abdominal sternite IX." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: continuous_with AISM:0004110 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite VIII relationship: continuous_with AISM:0004119 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite IX relationship: part_of AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen [Term] id: AISM:0004124 name: abdominal sternite IX-phallobase conjunctiva def: "The conjunctiva of the insect abdomen that connects the abdominal sternite IX and the abdominal sternite X." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: continuous_with AISM:0004065 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! phallobase relationship: continuous_with AISM:0004119 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite IX relationship: part_of AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen [Term] id: AISM:0004125 name: prothorax {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Prothorax: 1st thoracic segment, always completely wingless in extant hexapods.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The region of the cuticle of the insect thorax that is anteriorly connected to the head by the neck membrane, posteriorly connected to the mesothorax by the prothorax-mesothorax conjunctiva, and contains the pronotum, the propeluron, the prosternum and one pair of legs." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: anteriorly_connected_to AISM:0000098 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! neck membrane relationship: has_part AISM:0000034 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! fore leg relationship: has_part AISM:0000059 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pronotum relationship: has_part AISM:0000060 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labial palpomere relationship: has_part AISM:0000061 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prosternum relationship: part_of AISM:0000108 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect thorax relationship: posteriorly_connected_to AISM:0000046 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prothoracic-mesothoracic conjunctiva property_value: IAO:0000589 "cuticle of prothorax" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004126 name: mesothorax {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Mesothorax: 2nd thoracic segment, anterior segment of pterothorax; bearing forewings (groundplan of Pterygota).\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The region of the cuticle of the pterothorax that bears mid legs and fore wings." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: has_part AISM:0000035 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mid leg relationship: has_part AISM:0000037 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! fore wing relationship: part_of AISM:0004166 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pterothorax property_value: IAO:0000589 "cuticle of mesothorax" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004127 name: metathorax {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Metathorax: 3rd thoracic segment, posterior segment of pterothorax; bearing hindwings (groundplan of Pterygota).\"", term:modified="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The region of the cuticle of the pterothorax that bears the hind legs and the hind wings." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: has_part AISM:0000036 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! hind leg relationship: has_part AISM:0000038 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! hind wing relationship: part_of AISM:0004166 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pterothorax property_value: IAO:0000589 "cuticle of metathorax" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004128 name: notum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Notum: larger anterior part of tergum, composed of presutum, scutum and scutellum.\""} def: "The dorsal region of the cuticle of the insect thorax that is attached to the dorsal margin of the pleuron." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} synonym: "tergum" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Tergum: dorsal wall of a thoracic (or abdominal) segment.\""} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle [Term] id: AISM:0004129 name: pleuron {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Pleuron: lateral wall of thoracic segments, almost always divided by pleural ridge into anterior episternum and posterior epimeron.\""} def: "The region of cuticle on the lateral region of the insect thorax that is attached to the notum and the sternum and is attached to the coxae by skeletal muscle tissue and the basal coxal conjunctiva." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle is_a: UBERON:0000061 ! anatomical structure relationship: adjacent_to AISM:0004128 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! notum relationship: adjacent_to AISM:0004130 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! sternum relationship: continuous_with AISM:0000173 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! basal coxal conjunctiva [Term] id: AISM:0004130 name: sternum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Sternum: ventral wall of thoracic (or abdominal) segment, usually divided into presternum, basisternum, furcasternum and spinasternum in unspecialized hexapods; largely or completely invaginated in Holometabola (cryptosterny).\""} def: "The ventral region of the cuticle of the insect thorax that is attached to the ventral margin of the pleuron." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle [Term] id: AISM:0004131 name: pleurite {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Pleurite: sclerotized element of pleuron.\""} def: "The sclerite that is part of the pleuron." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: part_of AISM:0004129 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pleuron [Term] id: AISM:0004132 name: pleural ridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Pleural ridge: internal ridge, corresponding to externally visible pleural “suture”; separates episternum and epimeron; anterodorsally forming the pleural wing process and posteroventrally the pleuro-coxal joint.\""} def: "The ridge between the epimeron and the episternum in either the mesothorax or the metathorax." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000158 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular ridge relationship: continuous_with AISM:0004133 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! episternum relationship: continuous_with AISM:0004134 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! epimeron [Term] id: AISM:0004133 name: episternum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Episternum: part of pleuron anterior to pleural ridge.\""} def: "The sclerite of the insect thorax that is part of the pleuron and anterior to the pleural ridge and attached to the anterior margin of the epimeron." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: anterior_to AISM:0004132 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pleural ridge relationship: has_characteristic PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired relationship: part_of AISM:0004129 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pleuron [Term] id: AISM:0004134 name: epimeron {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Epimeron: part of pleuron posterior to pleural ridge.\""} def: "The sclerite of the insect thorax that is part of the pleuron and posterior to the pleural ridge and attached to the posterior margin of the episternum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: has_characteristic PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired relationship: part_of AISM:0004129 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pleuron relationship: posterior_to AISM:0004132 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pleural ridge [Term] id: AISM:0004135 name: trochantin {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Trochantin: small triangular or sickle-shaped ventral pleural sclerite; anteriorly articulating with coxa (trochantino-coxal joint).\""} def: "The sclerite that is located on the ventro-lateral region of the insect thorax and is attached to a coxa." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: adjacent_to AISM:0000077 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! coxa relationship: AISM:0000079 AISM:0000173 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by basal coxal conjunctiva [Term] id: AISM:0004136 name: presternum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Presternum: anteriormost part of sternum.\""} def: "The part of the sternum that is attached to the anterior margin of the basisternum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0004130 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! sternum [Term] id: AISM:0004137 name: basisternum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Basisternum: main part of sternum, between presternum and furcasternum.\""} def: "The part of the sternum that is attached to the posterior margin of the presternum and to the anterior margin of the furcasternum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0004130 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! sternum [Term] id: AISM:0004138 name: furcasternum {x_1.1:contributor="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Furcasternum (=sternellum): sternal element posterior to basisternum, area of origin of furca.\""} def: "The part of the sternum that is attached to the posterior margin of the basisternum and to the anterior margin of the spinasternum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} synonym: "sternellum" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Furcasternum (=sternellum): sternal element posterior to basisternum, area of origin of furca.\""} is_a: AISM:0004130 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! sternum [Term] id: AISM:0004139 name: spinasternum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Spinasternum: small posterior sternal element, determining the posterior segmental border; area of origin of spina.\""} def: "The part of the sternum that is attached to the posterior margin of the furcasternum and to the anterior margin of the poststernite." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0004130 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! sternum [Term] id: AISM:0004140 name: poststernite {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Poststernite: posteriormost sternal element.\""} def: "The part of the sternum that is attached to the posterior margin of the spinasternum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0004130 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! sternum [Term] id: AISM:0004141 name: cervical sclerite {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Cervical sclerite: articulatory sclerite embedded in the cervical membrane.\""} def: "The sclerite that is surrounded by the neck membrane." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: AISM:0000079 AISM:0000098 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by neck membrane [Term] id: AISM:0004142 name: propleuron def: "The region of the cuticle on the lateral region of the prothorax that is attached to the pronotum and the prosternum, and is attached to the procoxa by the procoxal muscle and the basal procoxal conjunctiva." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004129 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pleuron relationship: adjacent_to AISM:0000059 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pronotum relationship: adjacent_to AISM:0000061 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prosternum relationship: continuous_with AISM:0000106 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! basal procoxal conjunctiva relationship: continuous_with AISM:0000145 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! procoxal muscle [Term] id: AISM:0004143 name: postnotum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Postnotum: smaller posterior part of tergum, forming internal intersegmental phragma; attachment area for dorsal indirect flight muscles.\""} def: "The sclerite of the notum that is attached to the posterior margin of the scutellum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: part_of AISM:0004128 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! notum [Term] id: AISM:0004144 name: prescutum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Prescutum: anteriormost part of notum.\""} def: "The sclerite of the notum that is attached to the anterior margin of the scutum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: part_of AISM:0004128 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! notum [Term] id: AISM:0004145 name: scutum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Scutum: large anterior part of notum.\""} def: "The sclerite of the notum that is attached to the posterior margin of the prescutum and to the anterior margin of the scutellum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: part_of AISM:0004128 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! notum [Term] id: AISM:0004146 name: scutellum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Scutellum: smaller posterior part of notum.\""} def: "The sclerite of the notum that is attached to the posterior margin of the scutum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: part_of AISM:0004128 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! notum [Term] id: AISM:0004147 name: alinotum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Alinotum: part of the notum connected with the wing base.\""} def: "The sclerite that is on the lateral region of the notum and is adjacent to the wing." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: adjacent_to AISM:0000033 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing [Term] id: AISM:0004148 name: prealar sclerite {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Prealare (=prealar sclerite): small attachment area of short direct flight muscles.\""} def: "The sclerite of the pterothorax that is attached to some muscle." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} synonym: "prealare" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Prealare (=prealar sclerite): small attachment area of short direct flight muscles.\""} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: continuous_with UBERON:0014895 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! somatic muscle relationship: part_of AISM:0004166 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pterothorax [Term] id: AISM:0004149 name: prealar bridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Prealar bridge: prescutal process, bent downwards and linked with episternum.\""} def: "The region of cuticle of the dorso-lateral region of the pterothorax that is surrounded by the noto-pleural conjunctiva and articulated with the episternum." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: adjacent_to AISM:0004133 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! episternum relationship: continuous_with AISM:0004222 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! noto-pleural conjunctiva [Term] id: AISM:0004150 name: postalar bridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Postalar bridge: lateral postnotal margin bent downwards and connected with the epimeron.\""} def: "The region of cuticle of the dorso-lateral region of the pterothorax that is surrounded by the noto-pleural conjunctiva and articulated with the epimeron." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: adjacent_to AISM:0004134 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! epimeron relationship: continuous_with AISM:0004222 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! noto-pleural conjunctiva [Term] id: AISM:0004151 name: epipleurite {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Epipleurites: basalare and subalare.\""} def: "The sclerite of the insect thorax that is surrounded by the noto-pleural conjunctiva and is adjacent to the wing." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: adjacent_to AISM:0000033 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing relationship: AISM:0000079 AISM:0004080 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by precoxal sulcus relationship: part_of AISM:0000108 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect thorax [Term] id: AISM:0004152 name: basalare {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Basalare: sclerite associated with wing base, more or less distinctly separated from anepisternum; usually with internal muscle disc; attachment site of direct flight muscles.\""} def: "The epipleurite that is adjacent to the anepisternum, is attached to the pleuron via muscle, is surrounded by the noto-pleural conjunctiva, and is anterior to the first axillary sclerite." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0004151 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! epipleurite is_a: UBERON:0000061 ! anatomical structure relationship: adjacent_to AISM:0004154 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anepisternum relationship: AISM:0000079 AISM:0004222 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by noto-pleural conjunctiva relationship: anterior_to AISM:0000022 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! first axillary sclerite [Term] id: AISM:0004153 name: subalare {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Subalare: sclerite associated with wing base, usually embedded in membrane between tergum and pleuron; attachment site of direct flight muscles.\""} def: "The epipleurite that is adjacent to the notum, is attached to the coxa via muscle, is surrounded by the noto-pleural conjunctiva, and is posterior to the first axillary sclerite." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0004151 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! epipleurite is_a: UBERON:0000061 ! anatomical structure relationship: adjacent_to AISM:0004128 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! notum relationship: AISM:0000079 AISM:0004222 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by noto-pleural conjunctiva relationship: posterior_to AISM:0000022 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! first axillary sclerite [Term] id: AISM:0004154 name: anepisternum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Anepisternum: dorsal part of episternum, ventrally delimited by anapleural suture.\""} def: "The dorsal region of the episternum that is dorsal to the anapleural sulcus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: dorsal_to AISM:0004156 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anapleural sulcus relationship: has_characteristic PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired [Term] id: AISM:0004155 name: preepisternum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Preepisternum: anterior part of ventral episternal region; delimited from katepisternum by precoxal suture; largest part of ventrite in Holometabola.\""} def: "The region of cuticle on the antero-ventral region of the episternum that is anterior to the anapleural sulcus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: anterior_to AISM:0004156 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anapleural sulcus [Term] id: AISM:0004156 name: anapleural sulcus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Anapleural suture (=paracoxal suture): suture horizontally delimiting dorsal and ventral parts of episternum and (partially) epimeron; sometimes anteriorly widened and membranous (=anapleural cleft).\""} def: "The sulcus of the pleuron delimiting the dorsal region of the preepisternum and the ventral region of the anepisternum." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} synonym: "anapleural cleft" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Anapleural suture (=paracoxal suture): suture horizontally delimiting dorsal and ventral parts of episternum and (partially) epimeron; sometimes anteriorly widened and membranous (=anapleural cleft).\""} synonym: "paracoxal suture" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Anapleural suture (=paracoxal suture): suture horizontally delimiting dorsal and ventral parts of episternum and (partially) epimeron; sometimes anteriorly widened and membranous (=anapleural cleft).\""} is_a: AISM:0000162 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular sulcus relationship: part_of AISM:0004129 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pleuron [Term] id: AISM:0004157 name: ecdysial line def: "The anatomical line of weakness of the cuticle that allows molting and coincides with a suture." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} synonym: "molting line" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Molting lines (frontal and coronal sutures [=epicranial lines or sutures])\""} is_a: CARO:0000008 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anatomical line relationship: RO:0002008 AISM:0004028 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! coincident with cuticular suture [Term] id: AISM:0004158 name: katepisternum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Katepisternum: posterior part of ventral episternal region; separated from preepisternum by precoxal suture.\""} def: "The region of cuticle on the postero-ventral region of the episternum that is posterior to the anapleural sulcus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: posterior_to AISM:0004156 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anapleural sulcus [Term] id: AISM:0004159 name: anepimeron {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Anepimeron: dorsal part of epimeron (present as separate element in some groups).\""} def: "The region of the cuticle on the dorsal region of the epimeron." [] {creation_date="2021-04-10", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: has_characteristic PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired [Term] id: AISM:0004160 name: katepimeron {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Katepimeron: ventral part of epimeron (present as separate element in some groups).\""} def: "The region of cuticle on the ventral region of the epimeron." [] {creation_date="2021-04-10", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle [Term] id: AISM:0004161 name: axillary sclerite {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Axillary sclerites (=axillaria, pteralia): small sclerites of wing base (usually 3); articulating with notal wing processes.\""} def: "The sclerite that is surrounded by the basal wing conjunctiva." [] {creation_date="2021-04-10", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} synonym: "pteralia" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Pteralia: small sclerites of wing base (axillary sclerites + plates).\""} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: AISM:0000079 AISM:0004203 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by basal wing conjunctiva relationship: part_of AISM:0004258 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! axillary region of the insect wing [Term] id: AISM:0004162 name: precoxal ridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Precoxal ridge: mediolaterally directed ridge in front of coxa, corresponding with externally visible precoxal suture.\""} def: "The ridge that is anterior to a coxa, demarcated by the anapleural sulcus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0000158 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular ridge relationship: anterior_to AISM:0000077 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! coxa relationship: continuous_with AISM:0004156 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anapleural sulcus [Term] id: AISM:0004163 name: spina {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Spina: smaller posterior endoskeletal element of thoracic segments, unpaired, arising on spinasternum.\""} def: "The sclerite attached to the spinasternum." [] {creation_date="2021-04-10", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: continuous_with AISM:0004139 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! spinasternum [Term] id: AISM:0004165 name: cercus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Cerci: tactile appendages of segment XI, primarily multisegmented and tactile bearing setae.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The bilaterally paired region of the cuticle of the postabdomen located between the epiproct and the paraproct" [] {creation_date="2021-04-10", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle intersection_of: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! insect region of cuticle intersection_of: adjacent_to AISM:0004060 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! epiproct intersection_of: has_characteristic PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! bilaterally paired intersection_of: part_of AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! postabdomen relationship: adjacent_to AISM:0004060 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! epiproct relationship: adjacent_to AISM:0004061 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! paraproct relationship: has_characteristic PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired relationship: part_of AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postabdomen property_value: IAO:0000589 "cuticle of cercus" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004166 name: pterothorax {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Pterothorax: 2nd and 3nd thoracic segments; bearing wings (groundplan of Pterygota), meso- and metathorax.\""} def: "The region of cuticle of the insect thorax that contains the mesothorax and the metathorax and bears the mid legs, the hind legs and the wings." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: has_part AISM:0004126 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesothorax relationship: has_part AISM:0004127 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metathorax relationship: part_of AISM:0000108 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect thorax [Term] id: AISM:0004167 name: abdominal tergite X-paraproct conjunctiva def: "The conjunctiva of the postabdomen that joins the abdominal tergite X and each paraproct." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: continuous_with AISM:0004061 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! paraproct relationship: continuous_with AISM:0004118 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite X relationship: part_of AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postabdomen [Term] id: AISM:0004168 name: trochanter {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Trochanter: 2nd element of leg, usually small and triangular.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of a leg attached to the distal margin of the coxa by the coxal-trochanteral conjunctiva and to the proximal margin of the femur by the trochantero-femoral conjunctiva." [] {term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0000063 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! appendage segment relationship: AISM:0000078 AISM:0004174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles trochantero-femoral conjunctiva relationship: AISM:0000079 AISM:0004170 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by coxal-trochanteral conjunctiva relationship: has_characteristic PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired relationship: part_of AISM:0000031 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect leg property_value: IAO:0000589 "cuticle of trochanter" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004169 name: tarsus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Tarsus: 5th part of leg; undivided in entognathous orders, composed of 3–5 tarsomeres in most groups of Insecta.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of the leg that is composed of tarsomeres connected to each other by intertarsomeral conjunctiva. The first tarsomere is connected to the distal margin of the tibia by the tibio-tarsal conjunctiva." [] {term:modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0000063 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! appendage segment relationship: AISM:0000079 AISM:0004182 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by tibio-tarsal conjunctiva relationship: has_characteristic PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired relationship: has_part AISM:0000074 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tarsomere relationship: part_of AISM:0000031 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect leg property_value: IAO:0000589 "cuticle of tarsus" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004170 name: coxal-trochanteral conjunctiva def: "The conjunctiva of the leg joining the distal margin of a coxa and the proximal margin of a femur." [] {creation_date="2021-03-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000102 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! ring conjunctiva relationship: AISM:0000078 AISM:0004168 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles trochanter relationship: part_of AISM:0000031 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect leg [Term] id: AISM:0004171 name: protrochanter {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of a fore leg attached to the distal margin of the procoxa by the procoxal-protrochanteral conjunctiva and to the proximal margin of the profemur by the protrochantero-profemoral conjunctiva." [] {term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0004168 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! trochanter relationship: AISM:0000078 AISM:0004175 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles protrochantero-profemoral conjunctiva relationship: AISM:0000079 AISM:0000123 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by procoxal-protrochanteral conjunctiva relationship: part_of AISM:0000034 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! fore leg property_value: IAO:0000589 "cuticle of protrochanter" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004172 name: mesotrochanter {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of a mid leg attached to the distal margin of the mesocoxa by the mesocoxal-mesotrochanteral conjunctiva and to the proximal margin of the mesofemur by the mesotrochantero-mesofemoral conjunctiva." [] {term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0004168 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! trochanter relationship: AISM:0000078 AISM:0004176 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles mesotrochantero-mesofemoral conjunctiva relationship: AISM:0000079 AISM:0000124 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by mesocoxal-mesotrochanteral conjunctiva relationship: part_of AISM:0000035 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mid leg property_value: IAO:0000589 "cuticle of mesotrochanter" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004173 name: metatrochanter {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of a hind leg attached to the distal margin of the metacoxa by the metacoxal-metatrochanteral conjunctiva and to the proximal margin of the metafemur by the metatrochantero-metafemoral conjunctiva." [] {term:modified="2021-12-08", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0004168 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! trochanter relationship: AISM:0000078 AISM:0004177 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles metatrochantero-metafemoral conjunctiva relationship: AISM:0000079 AISM:0000125 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by metacoxal-metatrochanteral conjunctiva relationship: part_of AISM:0000036 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! hind leg property_value: IAO:0000589 "cuticle of metatrochanter" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004174 name: trochantero-femoral conjunctiva def: "The conjunctiva that encircles the femur by joining the distal margin of the trochanter and the proximal margin of the femur." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"} is_a: AISM:0000102 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! ring conjunctiva relationship: AISM:0000078 AISM:0000076 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles femur relationship: part_of AISM:0000031 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect leg [Term] id: AISM:0004175 name: protrochantero-profemoral conjunctiva def: "The conjunctiva that encircles the profemur by joining the distal margin of the protrochanter and the proximal margin of the profemur." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0004174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! trochantero-femoral conjunctiva relationship: AISM:0000078 AISM:0000070 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles profemur relationship: part_of AISM:0000034 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! fore leg [Term] id: AISM:0004176 name: mesotrochantero-mesofemoral conjunctiva def: "The conjunctiva that encircles the mesofemur by joining the distal margin of the mesotrochanter and the proximal margin of the mesofemur." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0004174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! trochantero-femoral conjunctiva relationship: AISM:0000078 AISM:0000071 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles mesofemur relationship: part_of AISM:0000035 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mid leg [Term] id: AISM:0004177 name: metatrochantero-metafemoral conjunctiva def: "The conjunctiva that encircles the metafemur by joining the distal margin of the metatrochanter and the proximal margin of the metafemur." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0004174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! trochantero-femoral conjunctiva relationship: AISM:0000078 AISM:0000072 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles metafemur relationship: part_of AISM:0000036 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! hind leg [Term] id: AISM:0004178 name: femoro-tibial conjunctiva def: "The conjunctiva that encircles the tibia by joining the distal margin of the femur and the proximal margin of the tibia." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0000102 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! ring conjunctiva relationship: AISM:0000078 AISM:0000075 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles tibia relationship: AISM:0000079 AISM:0000076 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by femur relationship: part_of AISM:0000031 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect leg [Term] id: AISM:0004179 name: profemoro-protibial conjunctiva def: "The conjunctiva that encircles the protibia by joining the distal margin of the profemur and the proximal margin of the protibia." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0004178 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! femoro-tibial conjunctiva relationship: AISM:0000078 AISM:0000067 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles protibia relationship: AISM:0000079 AISM:0000070 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by profemur relationship: part_of AISM:0000034 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! fore leg [Term] id: AISM:0004180 name: mesofemoro-mesotibial conjunctiva def: "The conjunctiva that encircles the mesotibia by joining the distal margin of the mesofemur and the proximal margin of the mesotibia." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0004178 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! femoro-tibial conjunctiva relationship: AISM:0000078 AISM:0000068 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles mesotibia relationship: AISM:0000079 AISM:0000071 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by mesofemur relationship: part_of AISM:0000035 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mid leg [Term] id: AISM:0004181 name: metafemoro-metatibial conjunctiva def: "The conjunctiva that encircles the metatibia by joining the distal margin of the metafemur and the proximal margin of the metatibia." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0004178 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! femoro-tibial conjunctiva relationship: AISM:0000078 AISM:0000069 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles metatibia relationship: AISM:0000079 AISM:0000072 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by metafemur relationship: part_of AISM:0000036 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! hind leg [Term] id: AISM:0004182 name: tibio-tarsal conjunctiva def: "The conjunctiva that encircles the tarsus by joining the distal margin of the tibia and the proximal margin of the tarsus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0000102 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! ring conjunctiva relationship: AISM:0000078 AISM:0004169 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles tarsus relationship: AISM:0000079 AISM:0000075 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by tibia relationship: part_of AISM:0000031 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect leg [Term] id: AISM:0004183 name: protibio-protarsal conjunctiva def: "The conjunctiva that encircles the protarsus by joining the distal margin of the protibia and the proximal margin of the protarsus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0004182 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tibio-tarsal conjunctiva relationship: AISM:0000078 AISM:0004190 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles protarsus relationship: AISM:0000079 AISM:0000067 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by protibia relationship: part_of AISM:0000034 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! fore leg [Term] id: AISM:0004184 name: mesotibio-mesotarsal conjunctiva def: "The conjunctiva that encircles the mesotarsus by joining the distal margin of the mesotibia and the proximal margin of the mesotarsus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0004182 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tibio-tarsal conjunctiva [Term] id: AISM:0004185 name: metatibio-metatarsal conjunctiva def: "The conjunctiva that encircles the metatarsus by joining the distal margin of the metatibia and the proximal margin of the metatarsus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0004182 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tibio-tarsal conjunctiva relationship: AISM:0000078 AISM:0004188 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles metatarsus relationship: AISM:0000079 AISM:0000069 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by metatibia relationship: part_of AISM:0000036 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! hind leg [Term] id: AISM:0004186 name: mesopleuron def: "The region of the cuticle on the lateral region of the mesothorax that is attached to the mesonotum and the mesosternum, and is attached to the mesocoxa by the mesocoxal muscle and the basal mesocoxal conjunctiva." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004129 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pleuron relationship: adjacent_to AISM:0000052 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesonotum relationship: adjacent_to AISM:0000121 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesosternum relationship: continuous_with AISM:0000085 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesocoxal muscle relationship: continuous_with AISM:0000103 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! basal mesocoxal conjunctiva [Term] id: AISM:0004187 name: tarso-pretarsal conjunctiva def: "The conjunctiva that encircles the pretarsus by joining the distal margin of the distalmost tarsomere and the proximal margin of the pretarsus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0000102 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! ring conjunctiva relationship: AISM:0000078 AISM:0000047 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles pretarsus relationship: AISM:0000079 AISM:0004169 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by tarsus relationship: part_of AISM:0000031 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect leg [Term] id: AISM:0004188 name: metatarsus {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of the leg that is composed of metatarsomeres connected to each other by intertarsomeral conjunctiva. The first metatarsomere is connected to the distal margin of the metatibia by the metatibio-metatarsal conjunctiva." [] {term:modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0004169 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tarsus relationship: AISM:0000079 AISM:0004185 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by metatibio-metatarsal conjunctiva relationship: part_of AISM:0000036 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! hind leg property_value: IAO:0000589 "cuticle of metatarsus" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004189 name: mesotarsus {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of the mid leg that is composed of mesotarsomeres connected to each other by intertarsomeral conjunctiva. The first mesotarsomere is connected to the distal margin of the mesotibia by the mesotibio-mesotarsal conjunctiva." [] {term:modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0004169 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tarsus relationship: AISM:0000079 AISM:0004184 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by mesotibio-mesotarsal conjunctiva property_value: IAO:0000589 "cuticle of mesotarsus" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004190 name: protarsus {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the segment of the leg that is composed of protarsomeres connected to each other by intertarsomeral conjunctiva. The first protarsomere is connected to the distal margin of the protibia by the protibio-protarsal conjunctiva." [] {term:modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0004169 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tarsus relationship: AISM:0000079 AISM:0004183 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by protibio-protarsal conjunctiva relationship: part_of AISM:0000034 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! fore leg property_value: IAO:0000589 "cuticle of protarsus" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004191 name: protarso-propretarsal conjunctiva def: "The conjunctiva that encircles the propretarsus by joining the distal margin of the distalmost protarsomere and the proximal margin of the propretarsus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0004187 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tarso-pretarsal conjunctiva relationship: AISM:0000078 AISM:0004194 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles propretarsus relationship: AISM:0000079 AISM:0004190 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by protarsus [Term] id: AISM:0004192 name: mesotarso-mesopretarsal conjunctiva def: "The conjunctiva that encircles the mesopretarsus by joining the distal margin of the distalmost mesotarsomere and the proximal margin of the mesopretarsus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0004187 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tarso-pretarsal conjunctiva relationship: AISM:0000078 AISM:0004195 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles mesopretarsus relationship: AISM:0000079 AISM:0004189 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by mesotarsus [Term] id: AISM:0004193 name: metatarso-metapretarsal conjunctiva def: "The conjunctiva that encircles the metapretarsus by joining the distal margin of the distalmost metatarsomere and the proximal margin of the metapretarsus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0004187 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tarso-pretarsal conjunctiva relationship: AISM:0000078 AISM:0004196 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles metapretarsus relationship: AISM:0000079 AISM:0004188 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by metatarsus [Term] id: AISM:0004194 name: propretarsus {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the appendage of the fore leg that is attached to the protarsus by the protarso-propretarsal conjunctiva." [] {term:modified="2021-12-10", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0000047 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pretarsus relationship: continuous_with AISM:0004191 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! protarso-propretarsal conjunctiva relationship: part_of AISM:0000034 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! fore leg property_value: IAO:0000589 "cuticle of propretarsus" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004195 name: mesopretarsus {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the appendage of the mid leg that is attached to the mesotarsus by the mesotarso-mesopretarsal conjunctiva." [] {term:modified="2021-12-10", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0000047 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pretarsus relationship: continuous_with AISM:0004192 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesotarso-mesopretarsal conjunctiva relationship: part_of AISM:0000035 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mid leg property_value: IAO:0000589 "cuticle of mesopretarsus" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004196 name: metapretarsus {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the appendage of the hind leg that is attached to the metatarsus by the metatarso-metapretarsal conjunctiva." [] {term:modified="2021-12-10", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0000047 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pretarsus relationship: continuous_with AISM:0004193 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metatarso-metapretarsal conjunctiva relationship: part_of AISM:0000036 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! hind leg property_value: IAO:0000589 "cuticle of metapretarsus" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004197 name: insect anus def: "The orifice on the postabdomen at the posterior margin of the digestive tract, connected to the epiproct and paraprocti." [] {creation_date="2021-04-10", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: UBERON:0000161 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! orifice relationship: adjacent_to AISM:0004060 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! epiproct relationship: adjacent_to AISM:0004061 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! paraproct relationship: AISM:0000079 AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by postabdomen [Term] id: AISM:0004198 name: gonostylus IX {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The region of the cuticle of the postabdomen that is paired and connected to the anterior region of the gonocoxa IX." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: has_characteristic PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired relationship: part_of AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postabdomen property_value: IAO:0000589 "cuticle of gonostylus IX" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004199 name: cercomere {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of the mere that is part of the cercus." [] {term:modified="2021-12-08", creation_date="2021-08-04", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000073 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mere relationship: part_of AISM:0004165 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cercus property_value: IAO:0000589 "cuticle of cercomere" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004200 name: paramero-aedeagal conjunctiva def: "The conjunctiva of the postabdomen that joins the parameres and the aedeagus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: continuous_with AISM:0004062 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! aedeagus relationship: continuous_with AISM:0004064 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! paramere relationship: part_of AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postabdomen [Term] id: AISM:0004201 name: phallobasal-parameral conjunctiva def: "The conjunctiva of the postabdomen that joins the phallobase and the parameres." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: continuous_with AISM:0004064 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! paramere relationship: continuous_with AISM:0004065 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! phallobase relationship: part_of AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postabdomen [Term] id: AISM:0004202 name: propleuro-prosternal conjunctiva def: "The conjunctiva of the prothorax that joins the propleura and the prosternum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: continuous_with AISM:0000061 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prosternum relationship: continuous_with AISM:0004142 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! propleuron relationship: part_of AISM:0004125 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prothorax [Term] id: AISM:0004203 name: basal wing conjunctiva def: "The conjunctiva of the pterothorax that surrounds the wing." [] {creation_date="2021-04-10", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: AISM:0000078 AISM:0000033 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircles insect wing relationship: part_of AISM:0004166 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pterothorax [Term] id: AISM:0004204 name: tergo-trochantinal muscle def: "The insect thoracic muscle that attaches to the notum and to the trochantin." [] {creation_date="2021-04-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0002065 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect thoracic muscle relationship: attaches_to AISM:0004128 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! notum relationship: attaches_to AISM:0004135 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! trochantin property_value: curator_notes "For muscular terminology, tergum has been traditionally used instead of notum, even though \"notum\" is the prererred term to refer to the dorsal region of the cuticle of the insect thorax that is attached to the dorsal margin of the pleuron." xsd:string {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} [Term] id: AISM:0004205 name: pronoto-protrochantinal muscle def: "The tergo-trochantinal muscle that is attached to the pronotum and the protrochantin." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0004204 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tergo-trochantinal muscle relationship: attaches_to AISM:0000055 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! protrochantin relationship: attaches_to AISM:0000059 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pronotum [Term] id: AISM:0004206 name: mesonoto-mesotrochantinal muscle def: "The tergo-trochantinal muscle that is attached to the mesonotum and the mesotrochantin." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0004204 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! tergo-trochantinal muscle relationship: attaches_to AISM:0000052 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesonotum relationship: attaches_to AISM:0000054 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesotrochantin [Term] id: AISM:0004207 name: metanoto-metatrochantinal muscle def: "The tergo-trochantinal muscle that is attached to the metanotum and the metatrochantin." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0004204 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tergo-trochantinal muscle relationship: attaches_to AISM:0000056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metatrochantin relationship: attaches_to AISM:0000169 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metanotum [Term] id: AISM:0004208 name: tergo-tergal muscle def: "The insect thoracic muscle that extends between two nota (or terga)." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0002065 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect thoracic muscle relationship: attaches_to AISM:0004128 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! notum [Term] id: AISM:0004209 name: pronoto-mesonotal muscle def: "The insect thoracic muscle that extends between the pronotum and the mesonotum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0004208 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! tergo-tergal muscle relationship: attaches_to AISM:0000052 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesonotum relationship: attaches_to AISM:0000059 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pronotum [Term] id: AISM:0004210 name: mesonoto-metanotal muscle def: "The insect thoracic muscle that extends between the mesonotum and the metanotum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0004208 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! tergo-tergal muscle relationship: attaches_to AISM:0000052 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesonotum relationship: attaches_to AISM:0000169 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metanotum [Term] id: AISM:0004211 name: tergo-coxal muscle def: "The insect thoracic muscle that extends between the notum (or tergum) and the coxa." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0002065 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect thoracic muscle relationship: attaches_to AISM:0000077 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! coxa relationship: attaches_to AISM:0004128 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! notum [Term] id: AISM:0004212 name: tergo-trochanteral muscle def: "The insect thoracic muscle that extends between the notum (or tergum) and the trochanter." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0002065 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect thoracic muscle relationship: attaches_to AISM:0004128 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! notum relationship: attaches_to AISM:0004168 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! trochanter [Term] id: AISM:0004213 name: pleuro-coxal muscle def: "The insect thoracic muscle that attaches to the pleuron and to a coxa." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0002065 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect thoracic muscle relationship: attaches_to AISM:0000077 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! coxa relationship: attaches_to AISM:0004129 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pleuron [Term] id: AISM:0004214 name: furco-coxal muscle def: "The insect thoracic muscle that is attached to a furca and to a coxa." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-08"} is_a: AISM:0002065 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect thoracic muscle relationship: attaches_to AISM:0000077 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! coxa relationship: attaches_to AISM:0000144 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! furca [Term] id: AISM:0004215 name: furco-trochanteral muscle def: "The insect thoracic muscle that is attached to a furca and to a trochanter." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-08"} is_a: AISM:0002065 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect thoracic muscle relationship: attaches_to AISM:0000144 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! furca relationship: attaches_to AISM:0004168 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! trochanter [Term] id: AISM:0004216 name: interfurcal muscle def: "The insect thoracic muscle that extends between two furcae." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0002065 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect thoracic muscle relationship: attaches_to AISM:0000144 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! furca [Term] id: AISM:0004217 name: profurco-mesofurcal muscle def: "The insect thoracic muscle that extends between the profurca and the mesofurca." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0004216 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! interfurcal muscle relationship: attaches_to AISM:0000141 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesofurca relationship: attaches_to AISM:0000143 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! profurca [Term] id: AISM:0004218 name: mesofurco-metafurcal muscle def: "The insect thoracic muscle that extends between the mesofurca and the metafurca." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0004216 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! interfurcal muscle relationship: attaches_to AISM:0000141 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesofurca relationship: attaches_to AISM:0000142 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metafurca [Term] id: AISM:0004219 name: mesonoto-mesopleural conjuntiva def: "The noto-pleural conjunctiva that joins the mesonotum and the mesopleuron." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0004222 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! noto-pleural conjunctiva relationship: continuous_with AISM:0000052 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesonotum relationship: continuous_with AISM:0004186 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesopleuron [Term] id: AISM:0004220 name: pronoto-propleural conjunctiva def: "The noto-pleural conjunctiva that joins the pronotum and the propleuron." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0004222 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! noto-pleural conjunctiva relationship: continuous_with AISM:0000059 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pronotum relationship: continuous_with AISM:0004142 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! propleuron [Term] id: AISM:0004221 name: metanoto-metapleural conjunctiva def: "The noto-pleural conjunctiva that joins the metanotum and the metapleuron." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0004222 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! noto-pleural conjunctiva relationship: continuous_with AISM:0000119 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metapleuron relationship: continuous_with AISM:0000169 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metanotum [Term] id: AISM:0004222 name: noto-pleural conjunctiva def: "The conjunctiva of the insect thorax that joins the notum and the pleuron." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: continuous_with AISM:0004128 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! notum relationship: continuous_with AISM:0004129 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pleuron relationship: part_of AISM:0000108 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect thorax [Term] id: AISM:0004223 name: third axillary sclerite def: "The axillary sclerite that is connected via muscle to the mesopleuron and is posterior to the first axillary sclerite." [] {creation_date="2021-04-10", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004161 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! axillary sclerite relationship: posterior_to AISM:0000022 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! first axillary sclerite [Term] id: AISM:0004224 name: ventral second axillary sclerite def: "The axillary sclerite that is on the ventral region of the basal wing conjunctiva." [] {creation_date="2021-04-10", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004161 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! axillary sclerite [Term] id: AISM:0004225 name: mesophragma def: "The phragma of the metanotum that attaches to muscles attached to the mesonotum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0002048 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! phragma relationship: part_of AISM:0000169 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metanotum [Term] id: AISM:0004226 name: mesophragmo-abdominal tergite I muscle def: "The insect thoracic muscle that extends between the mesophragma and the abdominal tergite I." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0004208 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! tergo-tergal muscle relationship: attaches_to AISM:0000021 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite I relationship: attaches_to AISM:0004225 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesophragma [Term] id: AISM:0004227 name: metafurco-abdominal sternite muscle def: "The insect thoracic muscle that extends between the metafurca and an abdominal sternite." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0002065 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect thoracic muscle relationship: attaches_to AISM:0000142 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! metafurca relationship: attaches_to AISM:0004058 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! abdominal sternite [Term] id: AISM:0004228 name: metaphragma def: "The phragma of the abdominal tergite I that attaches to muscles attached to the metanotum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0002048 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! phragma relationship: part_of AISM:0000021 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite I [Term] id: AISM:0004229 name: mesonoto-metanotal conjunctiva def: "The conjunctiva of the insect thorax that joins the mesonotum and the metanotum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: continuous_with AISM:0000052 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesonotum relationship: continuous_with AISM:0000169 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metanotum relationship: part_of AISM:0000108 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect thorax [Term] id: AISM:0004230 name: mesopleuro-mesocoxal conjunctiva def: "The conjunctiva of the mesothorax that joins the mesopleuron and the mesocoxa." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: continuous_with AISM:0000064 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesocoxa relationship: continuous_with AISM:0004186 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesopleuron relationship: part_of AISM:0004126 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesothorax [Term] id: AISM:0004231 name: mesopleuro-mesosternal conjunctiva def: "The conjunctiva of the mesothorax that joins the mesopleura and the mesosternum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0000004 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva relationship: continuous_with AISM:0000061 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prosternum relationship: continuous_with AISM:0004186 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesopleuron relationship: part_of AISM:0004125 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prothorax [Term] id: AISM:0004232 name: metasternum def: "The sclerite on the ventral region of the metathorax that bears the metafurca and is attached to the metapleuro-metasternal conjunctiva." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0004130 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! sternum relationship: continuous_with AISM:0004101 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metapleuro-metasternal conjunctiva relationship: has_part AISM:0000142 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metafurca [Term] id: AISM:0004233 name: mesosterno-mesocoxal conjunctiva def: "The conjunctiva of the mesothorax that joins the mesosternum and the mesocoxa." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva relationship: continuous_with AISM:0000064 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesocoxa relationship: continuous_with AISM:0000121 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesosternum relationship: part_of AISM:0004126 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesothorax [Term] id: AISM:0004234 name: circular pouch {creation_date="2021-07-21"} def: "The pouch that is circular." [] {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-07-21"} is_a: AISM:0000160 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular pouch relationship: has_characteristic PATO:0000411 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! circular [Term] id: AISM:0004235 name: ectodermal gland {AISM:0000171="Snodgrass RE (1993) Principles of Insect Morphology. Cornell University Press, 768 pp.\n\nhttps://www.jstor.org/stable/10.7591/j.ctv1nhm1j\n\n\"cells or groups of cells with highly specialized secretory functions, producing a great variety of substances which are discharged at the exterior or into invaginations of the body wall\""} def: "The region of cuticle that is continuous with glandular epithelial cells." [] {creation_date="2021-08-17", x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: continuous_with CL:0000150 {x_1.1:contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! glandular epithelial cell [Term] id: AISM:0004236 name: unicellular ectodermal gland {AISM:0000171="Snodgrass RE (1993) Principles of Insect Morphology. Cornell University Press, 768 pp.\n\nhttps://www.jstor.org/stable/10.7591/j.ctv1nhm1j\n\n\"one-celled gland usually larger than the cells surrounding it; discharges its products directly through the covering cuticula. [...] In many glands a minute cuticular ductule extends from the exterior into the body of each cell, allowing the secretion to pass out through an extremely thin layer of cuticula.\""} def: "The ectodermal gland that is composed of one cell" [] {creation_date="2021-08-16", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004235 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! ectodermal gland relationship: has_part CL:0000000 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cell [Term] id: AISM:0004237 name: cuticular lobe {term:modified="2021-12-08", AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"a rounded projection or protuberance\""} def: "The cuticular evagination that is largely membranous." [] {creation_date="2021-06-14", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000128 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-06-14"} ! multicellular cuticular evagination relationship: has_part AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-06-14"} ! conjunctiva [Term] id: AISM:0004238 name: multicellular ectodermal gland {AISM:0000171="Snodgrass RE (1993) Principles of Insect Morphology. Cornell University Press, 768 pp.\n\nhttps://www.jstor.org/stable/10.7591/j.ctv1nhm1j\n\n\"many-celled glands may be a group of cells situated at the surface of the body, but most of them are invaginations of the body wall.\""} def: "The ectodermal gland that is composed of multiple cells." [] {creation_date="2021-08-16", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004235 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! ectodermal gland [Term] id: AISM:0004239 name: occiput {AISM:0000171="Snodgrass RE (1993) Principles of Insect Morphology. Cornell University Press, 768 pp.\n\nhttps://www.jstor.org/stable/10.7591/j.ctv1nhm1j\n\n\"dorsal part of the posterior surface of the head between the occipital and the postoccipital sutures\""} def: "The region of cuticle on the posterodorsal region of the head capsule that is posterior to the occipital ridge and anterior to the postoccipital ridge." [] {creation_date="2021-08-16", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: anterior_to AISM:0004021 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postoccipital ridge relationship: posterior_to AISM:0004048 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! occipital ridge [Term] id: AISM:0004240 name: epicranial suture {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Y-shaped ecdysial sutures dividing vertex and frons, composed of\ncoronal suture and paired frontal sutures.\""} def: "The cuticular suture composed of both the coronal suture and paired frontal sutures." [] {creation_date="2021-08-16", term:modified="2021-12-10", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004028 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular suture relationship: has_part AISM:0004029 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! frontal suture relationship: has_part AISM:0004030 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! coronal suture [Term] id: AISM:0004241 name: temple {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"the part of the head above and behind the compound eyes\""} def: "The region of cuticle that is behind the compound eye." [] {creation_date="2021-08-16", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: posterior_to AISM:0004052 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect compound eye [Term] id: AISM:0004242 name: insect wing region {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"the principal areas of the wings differentiated in the wing-flexing insects (Neoptera), and often separated by distinct lines of folding, including the wing base, remigium, clavus, and jugum.\""} def: "The region of cuticle of the insect wing that has wing veins, folds, and conjunctiva." [] {creation_date="2021-09-07", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: has_part AISM:0004243 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing vein relationship: has_part AISM:0004244 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing fold [Term] id: AISM:0004243 name: insect wing vein {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"sclerotized, tubular structure supporting the membrane of the wings\""} def: "The region of cuticle of the insect wing that is less flexible than the wing conjunctiva." [] {creation_date="2021-09-07", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: part_of AISM:0000033 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing [Term] id: AISM:0004244 name: insect wing fold {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"line along which wings fold at rest\""} def: "The region of cuticle of the insect wing that is more flexible than the wing conjunctiva." [] {creation_date="2021-09-07", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle relationship: part_of AISM:0000033 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing [Term] id: AISM:0004245 name: anal field of the insect wing {IAO:0000232="Modified 2023-01-21: specifying insect wing field.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Anal field (=vannus): posterior part of wings, usually enlarged in Polyneoptera.\""} def: "The posterior region of the insect wing." [] {creation_date="2021-09-07", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} synonym: "vannus" EXACT [] is_a: AISM:0004242 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing region relationship: posterior_to AISM:0004311 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cubital field of the insect wing [Term] id: AISM:0004246 name: anal vein of the insect wing {IAO:0000232="Modified 2023-01-09: specifying insect wing vein.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Anal veins: longitudinal veins of the anal field proximally articulated with 3rd axillary sclerite; usually unbranched and arranged like a fan.\""} def: "The insect wing vein of the anal field that is posterior to the anal fold or the postcubitus and anterior to the jugal fold or the jugal veins." [] {creation_date="2021-09-07", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004243 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing vein relationship: RO:0001018 AISM:0004245 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! obsolete contained in anal field of the insect wing [Term] id: AISM:0004247 name: costal vein of the insect wing {IAO:0000232="Modified 2023-01-09: specifying insect wing vein.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Costa: main longitudinal vein along anterior wing margin, articulated with humeral plate.\""} def: "The insect wing vein of the costal field that is anterior to the subcosta." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004243 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing vein relationship: anterior_to AISM:0004257 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! subcostal vein of the insect wing relationship: RO:0001018 AISM:0004248 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! obsolete contained in costal field of the insect wing [Term] id: AISM:0004248 name: costal field of the insect wing {IAO:0000232="Modified 2023-01-21: specifying insect wing field.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Costal field (=remigium): anterior part of wing; usually largest region.\""} def: "The anterior region of the insect wing." [] {creation_date="2021-09-07", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} synonym: "remigium" EXACT [] is_a: AISM:0004242 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing region is_a: BSPO:0000078 ! distal region [Term] id: AISM:0004249 name: cubital vein of the insect wing {IAO:0000232="Modified 2023-01-09: specifying insect wing vein.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Cubitus: 5th main longitudinal vein.\""} def: "The insect wing vein that is posterior to the media and anterior to the postcubitus." [] {creation_date="2021-09-07", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004243 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing vein relationship: anterior_to AISM:0004255 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postcubital vein of the insect wing relationship: posterior_to AISM:0004252 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! medial vein of the insect wing [Term] id: AISM:0004250 name: jugal field of the insect wing {IAO:0000232="Modified 2023-01-21: specifying insect wing field.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Jugal field: small wing region posteriorly adjacent with anal field.\""} def: "The insect wing region that is posterior to the jugal fold." [] {creation_date="2021-09-07", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004242 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing region relationship: posterior_to AISM:0004253 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! jugal fold of the insect wing [Term] id: AISM:0004251 name: jugal vein of the insect wing {IAO:0000232="Modified 2023-01-09: specifying insect wing vein.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Jugal veins: veins of the jugal field.\""} def: "The insect wing vein in the jugal field, posterior to the jugal fold or to the anal veins." [] {creation_date="2021-09-07", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004243 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing vein relationship: RO:0001018 AISM:0004250 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! obsolete contained in jugal field of the insect wing [Term] id: AISM:0004252 name: medial vein of the insect wing {IAO:0000232="Modified 2023-01-09: specifying insect wing vein.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Media: 4th main longitudinal vein.\""} def: "The insect wing vein that is posterior to some radius and anterior to some cubitus." [] {creation_date="2021-09-07", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004243 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing vein relationship: anterior_to AISM:0004249 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cubital vein of the insect wing relationship: posterior_to AISM:0004256 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! radial vein of the insect wing [Term] id: AISM:0004253 name: jugal fold of the insect wing {IAO:0000232="Modified 2023-01-21: specifying insect wing fold.\njgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect wing fold that separates the anal field and the jugal field." [] {creation_date="2021-09-07", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} synonym: "plica jugalis" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Plica jugalis: separates the anal and jugal fields.\""} is_a: AISM:0004244 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing fold [Term] id: AISM:0004254 name: anal fold of the insect wing {IAO:0000232="Modified 2023-01-21: specifying insect wing fold.\njgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect wing fold that is posterior to the postcubitus and separates the costal field and the anal field." [] {creation_date="2021-09-07", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} synonym: "claval furrow" EXACT [] {AISM:0000171="Chapman RF (2012) The Insects: Structure and Function. Fifth Edition. Cambridge University Press. 959 pp. \n\nhttps://doi.org/10.1017/CBO9781139035460\n\n\"longitudinal flexion line which runs close to the CuP. This furrow allows the posterior part of the wing to flap up and down with respect to the rest of the wing.\""} synonym: "plica vannalis" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Plica vannalis: separates the costal and anal fields.\""} is_a: AISM:0004244 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing fold relationship: posterior_to AISM:0004255 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postcubital vein of the insect wing [Term] id: AISM:0004255 name: postcubital vein of the insect wing {IAO:0000232="Modified 2023-01-09: specifying insect wing vein.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Postcubitus: posteriormost longitudinal vein of the remigium.\""} def: "The insect wing vein that is posterior to the cubitus and anterior to the anal fold or the anal vein." [] {creation_date="2021-09-07", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004243 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing vein relationship: posterior_to AISM:0004249 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cubital vein of the insect wing [Term] id: AISM:0004256 name: radial vein of the insect wing {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Radius: 3rd main longitudinal vein.\"", IAO:0000232="Modified 2023-01-09: specifying insect wing vein.\njgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect wing vein that is posterior to the subcosta and anterior to the media." [] {creation_date="2021-09-07", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004243 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing vein relationship: anterior_to AISM:0004252 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! medial vein of the insect wing relationship: posterior_to AISM:0004257 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! subcostal vein of the insect wing [Term] id: AISM:0004257 name: subcostal vein of the insect wing {IAO:0000232="Modified 2023-01-09: specifying insect wing vein.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Subcosta: 2nd main longitudinal vein, following costal vein.\""} def: "The insect wing vein that is posterior to the costa and anterior to the radius." [] {creation_date="2021-09-07", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004243 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing vein relationship: anterior_to AISM:0004256 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! radial vein of the insect wing relationship: posterior_to AISM:0004247 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! costal vein of the insect wing [Term] id: AISM:0004258 name: axillary region of the insect wing {IAO:0000232="Modified 2023-01-21: specifying insect wing region.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Snodgrass RE (1993) Principles of Insect Morphology. Cornell University Press, 768 pp.\n\nhttps://www.jstor.org/stable/10.7591/j.ctv1nhm1j\n\n\"The region of the wing base containing the axillary sclerites\""} def: "The proximal region of the insect wing." [] {creation_date="2021-09-07", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004242 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing region is_a: BSPO:0000078 ! distal region [Term] id: AISM:0004259 name: basal fold of the insect wing {comment="Modified 2023-01-21: specifying insect wing fold.\njgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect wing fold that is distal to the axillary region." [] {creation_date="2021-09-07", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} synonym: "plica basalis" EXACT [] {AISM:0000171="Snodgrass RE (1993) Principles of Insect Morphology. Cornell University Press, 768 pp.\n\nhttps://www.jstor.org/stable/10.7591/j.ctv1nhm1j\n\n\"Plica basalis (bf).The basal fold of the wing, or line of flection between the base of the mediocubital fold and the axillary region, forming a prominent convex fold in the flexed wing extending between the median plates from the articulation of radius with the second axillary to the articulation of the vannal veins with the third axillary.\""} is_a: AISM:0004244 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing fold relationship: distal_to AISM:0004258 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! axillary region of the insect wing [Term] id: AISM:0004260 name: pretarsal claw {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Ungues: pretarsal claws; unpaired in Collembola and Protura, usually paired in Diplura and Insecta.\""} def: "The sclerite that is part of the pretarsus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-11-19"} synonym: "ungues" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Ungues: pretarsal claws; unpaired in Collembola and Protura, usually paired in Diplura and Insecta.\""} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: part_of AISM:0000047 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pretarsus [Term] id: AISM:0004261 name: empodium {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Empodium: a median process between the claws and pulvilli (if present). It arises from the distal end of the unguitractor plate, is spine-shaped or lobe-like and is sometimes similar in form to the pulvilli (“empodial pulvillus”).\" p. 43.", AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"a spine- or lobelike process of the unguitractor\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticular protrusion that is part of the pretarsus, ventral to the tarsal claws and medial to the pulvilli (if present)." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-11-19", IAO:0000232="Modified 2023-01-11: added medial to pulvilli.\njgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000008 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular protrusion relationship: AISM:0000012 AISM:0004308 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! medial_to pulvillus relationship: part_of AISM:0000047 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pretarsus relationship: ventral_to AISM:0004260 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pretarsal claw property_value: IAO:0000589 "cuticle of empodium" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004262 name: frontoclypeal sulcus def: "The sulcus that coincides with the frontoclypeal ridge and separated the frons from the clypeus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-11-19"} synonym: "epistomal sulcus" EXACT [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} synonym: "epistomal suture" EXACT [] {AISM:0000171="Lawrence J, Ślipiński A (2013) Adult morphology. In: Australian beetles volume 1: morphology, classification and keys. CSIRO Publishing, 30–63. \n\nhttps://www.publish.csiro.au/book/6466/\n\n[adjusted] the 'suture' separating the clypeus from the frons, representing the internal invagination of the epistomal ridge."} synonym: "frontoclypeal suture" EXACT [] {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"the suture between the frons and the clypeus\""} is_a: AISM:0000162 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular sulcus relationship: adjacent_to AISM:0004019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! clypeus relationship: adjacent_to AISM:0004020 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! frons relationship: RO:0002008 AISM:0004034 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! coincident with frontoclypeal ridge [Term] id: AISM:0004263 name: cibarium {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Anterior part of preoral space between epipharynx and hypopharynx.\"", creation_date="2021-12-15"} def: "The conjunctiva that is part of the head capsule and is continuous with the epipharynx and the hypopharynx." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-12-15"} is_a: AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-12-15"} ! conjunctiva relationship: continuous_with AISM:0000093 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-12-15"} ! hypopharynx relationship: continuous_with AISM:0000105 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-12-15"} ! epipharynx relationship: part_of AISM:0000019 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-12-15"} ! head capsule [Term] id: AISM:0004264 name: epistoma {creation_date="2022-02-21", AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"the oral margin or sclerite directly behind the labrum\""} def: "The region of cuticle that is posterior to the cuticle of the labrum." [] {creation_date="2022-02-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-02-21"} ! insect region of cuticle relationship: posterior_to AISM:0000042 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-02-21"} ! labrum [Term] id: AISM:0004265 name: subgenal sulcus {creation_date="2022-02-21", AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"the lateral submarginal groove of the cranium just above the bases of the gnathal appendages, extending between the anterior tentorial pit and the posterior tentorial pit\""} def: "The cuticular sulcus that is adjacent to the subgena and coincides with the subgenal ridge." [] {creation_date="2022-02-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} synonym: "subgenal suture" EXACT [] is_a: AISM:0000162 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-02-21"} ! cuticular sulcus relationship: adjacent_to AISM:0004027 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-02-21"} ! subgena relationship: RO:0002008 AISM:0004032 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-02-21"} ! coincident with subgenal ridge [Term] id: AISM:0004266 name: antennomere {creation_date="2022-06-20", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticle of a mere that is part of the cuticle of the antenna." [] {creation_date="2022-06-20", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000073 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-20"} ! mere relationship: part_of AISM:0000032 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-20"} ! antenna property_value: curator_notes "Given the high number of antennomeres occurring in some taxa, Arabic numerals are used instead of Roman numerals for practicality reasons." xsd:string {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} property_value: IAO:0000589 "cuticle of antennomere" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004267 name: postoccipital sulcus {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n[as postoccipital suture] \"posterior submarginal groove having the posterior tentorial pits in its lower end, separatig the postocciput from the rest of the cranium\"", creation_date="2022-06-17"} def: "The cuticular sulcus that coincides with the postoccipital ridge and is posterior to the occiput and anterior to the postocciput." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-17"} synonym: "postoccipital suture" EXACT [] {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"posterior submarginal groove having the posterior tentorial pits in its lower end, separatig the postocciput from the rest of the cranium\""} is_a: AISM:0000162 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-17"} ! cuticular sulcus relationship: anterior_to AISM:0004045 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-17"} ! postocciput relationship: posterior_to AISM:0004239 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-17"} ! occiput relationship: RO:0002008 AISM:0004021 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-17"} ! coincident with postoccipital ridge [Term] id: AISM:0004268 name: gular sulcus {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n[as gular suture] \"the line or division between the gula and the genae\""} def: "The cuticular sulcus that coincides with the gular ridge, separating the gula fron the gena" [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-17"} synonym: "gular suture" EXACT [] {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"the line or division between the gula and the genae\""} is_a: AISM:0000162 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-17"} ! cuticular sulcus relationship: adjacent_to AISM:0004026 {x_1.1:contributor="2022-06-17", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! gena relationship: adjacent_to AISM:0004035 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-17"} ! gula relationship: RO:0002008 AISM:0004036 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-17"} ! coincident with gular ridge [Term] id: AISM:0004269 name: mandibular incisor lobe {creation_date="2022-06-20", AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"toothed distal lobe of mandible\""} def: "The region of the cuticle that is distal and medial on the cuticle of the insect mandible." [] {creation_date="2022-06-20", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-20"} ! insect region of cuticle [Term] id: AISM:0004270 name: mandibular molar lobe {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"the ridged or roughened grinding surface of the mandible\"", creation_date="2022-06-20"} def: "The region of the cuticle that is proximal and medial on the cuticle of the insect mandible." [] {creation_date="2022-06-20", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} synonym: "mola" EXACT [] {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\nmola = molar lobe = \"the ridged or roughened grinding surface of the mandible\""} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-20"} ! insect region of cuticle is_a: BSPO:0000078 ! distal region [Term] id: AISM:0004271 name: prostheca {creation_date="2022-06-20", AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"mandibular region set with hair\""} def: "The cuticular lobe of the cuticle of the insect mandible between the mandibular molar lobe and the mandibular incisor lobe." [] {creation_date="2022-06-20", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} synonym: "lacinia mobilis" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"An articulated mesal appendage, the lacinia mobilis or prostheca, occurs in several groups. It can be sclerotized or largely membranous and is often equipped with microtrichia.\""} is_a: AISM:0004237 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-20"} ! cuticular lobe relationship: anterior_to AISM:0004270 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-20"} ! mandibular molar lobe relationship: part_of AISM:0000043 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-20"} ! insect mandible relationship: posterior_to AISM:0004269 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-20"} ! mandibular incisor lobe [Term] id: AISM:0004272 name: basistipes {creation_date="2022-06-23", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Basistipes: basolateral part of stipes.\""} def: "The region of cuticle on the lateral region of the cuticle of stipes, adjacent to the distal margin of the cuticle of the cardo, to the proximal margin of the cuticle of the palpifer, and adjacent to the proximal margin of the mediostipes." [] {creation_date="2022-06-23", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-23"} ! insect region of cuticle is_a: BSPO:0000078 ! distal region [Term] id: AISM:0004273 name: mediostipes {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Mediostipes: mesal part of stipes.\""} def: "The region of cuticle on the medial region of the cuticle of stipes, adjacent to the distal margin of the cuticle of the basistipes, and to the proximal margin of the cuticle of the galea and the lacinia." [] {creation_date="2022-06-23", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-23"} ! insect region of cuticle is_a: BSPO:0000078 ! distal region [Term] id: AISM:0004274 name: maxillary gland {AISM:0000171="Snodgrass RE (1993) Principles of Insect Morphology. Cornell University Press, 768 pp.\n\nhttps://www.jstor.org/stable/10.7591/j.ctv1nhm1j\n\n\"Glands present in some insects opening mesally at the bases of the maxillae\""} def: "The ectodermal gland continuous with the proximal region of the cuticle of the cardo." [] {creation_date="2022-06-23", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004235 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-23"} ! ectodermal gland [Term] id: AISM:0004275 name: hypopharyngeal sclerite def: "The sclerite that is continuous with the hypopharynx." [] {creation_date="2022-06-27", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-27"} ! insect sclerite relationship: continuous_with AISM:0000093 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-27"} ! hypopharynx [Term] id: AISM:0004276 name: thoracic foramen {creation_date="2022-06-27"} def: "The arthropod foramen that is part of the cuticle of the insect thorax." [] {creation_date="2022-06-27", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000197 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-27"} ! arthropod foramen relationship: part_of AISM:0000108 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-27"} ! insect thorax [Term] id: AISM:0004277 name: anterior prothoracic foramen {creation_date="2022-06-27"} def: "The thoracic foramen that is at the anterior margin of the cuticle of the prothorax." [] {creation_date="2022-06-27", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004276 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-27"} ! thoracic foramen [Term] id: AISM:0004278 name: posterior prothoracic foramen {creation_date="2022-06-27"} def: "The thoracic foramen that is at the posterior margin of the cuticle of the prothorax." [] {creation_date="2022-06-27", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004276 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-27"} ! thoracic foramen [Term] id: AISM:0004279 name: anterior mesothoracic foramen {creation_date="2022-06-27"} def: "The thoracic foramen that is at the anterior margin of the cuticle of the mesothorax." [] {creation_date="2022-06-27", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004276 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-27"} ! thoracic foramen [Term] id: AISM:0004280 name: posterior mesothoracic foramen {creation_date="2022-06-27"} def: "The thoracic foramen that is at the posterior margin of the cuticle of the mesothorax." [] {creation_date="2022-06-27", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004276 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-27"} ! thoracic foramen [Term] id: AISM:0004281 name: posterior metathoracic foramen {creation_date="2022-06-27"} def: "The thoracic foramen that is at the posterior margin of the cuticle of the metathorax." [] {creation_date="2022-06-27", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004276 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-27"} ! thoracic foramen [Term] id: AISM:0004282 name: anterior metathoracic foramen {creation_date="2022-06-27"} def: "The thoracic foramen that is at the anterior margin of the cuticle of the metathorax." [] {creation_date="2022-06-27", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004276 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-27"} ! thoracic foramen [Term] id: AISM:0004283 name: insect body segment {creation_date="2023-01-09", AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"segment, subdivision of the body between areas of flexibility associated with muscle attachments\"", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect region of integument that is continuous with conjunctiva and attached to somatic muscle." [] {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} xref: http://flybase.org/cgi-bin/fbcvq.html?query=FBbt\:00000003 "segment" {def="One of the repeated divisions of the whole organism."} xref: http://purl.obolibrary.org/obo/HAO_0000929 "segment" {def="An anatomical structure that is metameric and is connected to other metameric subdivisions by muscles and is delimited by its sclerites."} is_a: UBERON:6007284 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect region of integument relationship: attaches_to UBERON:0014895 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! somatic muscle relationship: continuous_with AISM:0000004 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! conjunctiva [Term] id: AISM:0004284 name: insect appendage segment {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"segment, subdivision of an appendage between areas of flexibility associated with muscle attachments\""} def: "The insect region of integument that has a ring sclerirte, continuous with ring conjunctiva, and attached to somatic muscle." [] {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: UBERON:6007284 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect region of integument relationship: attaches_to UBERON:0014895 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! somatic muscle relationship: continuous_with AISM:0000102 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! ring conjunctiva relationship: has_part AISM:0000062 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! ring sclerite [Term] id: AISM:0004285 name: insect cephalic segment {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect body segment that is part of the insect head." [] {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} xref: https://flybase.org/cgi-bin/cvreport.pl?cvterm=FBbt\:00000006 "head segment" {def="Any segment (FBbt:00000003) that is part of some head (FBbt:00000004)."} is_a: AISM:0004283 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect body segment is_a: PR:000050567 ! protein-containing material entity relationship: has_part AISM:0000107 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect head [Term] id: AISM:0004286 name: insect thoracic segment {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect body segment that is part of the insect thorax." [] {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} xref: http://flybase.org/cgi-bin/cvreport.pl?cvterm=FBbt\:00000016 "thoracic segment" {def="Any segment (FBbt:00000003) that is part of some thorax (FBbt:00000015)."} is_a: AISM:0004283 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect body segment relationship: has_part AISM:0000108 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect thorax [Term] id: AISM:0004287 name: insect abdominal segment {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect body segment that is part of the insect abdomen." [] {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} xref: http://flybase.org/cgi-bin/cvreport.pl?cvterm=FBbt\:00000021 "abdominal segment" {def="Metameric subdivision of the abdomen."} is_a: AISM:0004283 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect body segment relationship: has_part AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdomen [Term] id: AISM:0004288 name: insect abdominal segment I {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect body segment that is part of the insect abdomen and is posterior to the insect metathoracic segment." [] {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} xref: http://flybase.org/cgi-bin/cvreport.pl?cvterm=FBbt\:00000022 "abdominal segment 1" {def="Most anterior segment of the abdomen."} is_a: AISM:0004287 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment relationship: has_part AISM:0000021 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! abdominal tergite I relationship: has_part AISM:0004100 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! abdominal sternite I relationship: posterior_to AISM:0004300 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect metathoracic segment [Term] id: AISM:0004289 name: insect abdominal segment II {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect abdominal segment that is posterior to the insect abdominal segment I and composed of abdominal tergite II and abdominal sternite II." [] {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} xref: http://flybase.org/cgi-bin/cvreport.pl?cvterm=FBbt\:00000023 "abdominal segment 2" {def="Second most anterior segment of the abdomen."} is_a: AISM:0004287 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment relationship: has_part AISM:0004085 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! abdominal tergite II relationship: has_part AISM:0004104 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! abdominal sternite II relationship: posterior_to AISM:0004288 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment I [Term] id: AISM:0004290 name: insect abdominal segment III {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect abdominal segment that is posterior to the insect abdominal segment II and composed of abdominal tergite III and abdominal sternite III." [] {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} xref: http://flybase.org/cgi-bin/cvreport.pl?cvterm=FBbt\:00000024 "abdominal segment 3" {def="Third most anterior segment of the abdomen."} is_a: AISM:0004287 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment relationship: has_part AISM:0004087 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! abdominal tergite III relationship: has_part AISM:0004105 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! abdominal sternite III relationship: posterior_to AISM:0004289 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment II [Term] id: AISM:0004291 name: insect abdominal segment IV {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect abdominal segment that is posterior to the insect abdominal segment III and composed of abdominal tergite IV and abdominal sternite IV." [] {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} xref: http://flybase.org/cgi-bin/cvreport.pl?cvterm=FBbt\:00000025 "abdominal segment 4" {def="Fourth most anterior segment of the abdomen."} is_a: AISM:0004287 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment relationship: has_part AISM:0004090 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! abdominal tergite IV relationship: has_part AISM:0004106 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! abdominal sternite IV relationship: posterior_to AISM:0004290 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment III [Term] id: AISM:0004292 name: insect abdominal segment V {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect abdominal segment that is posterior to the insect abdominal segment IV and composed of abdominal tergite V and abdominal sternite V." [] {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} xref: http://flybase.org/cgi-bin/cvreport.pl?cvterm=FBbt\:00000026 "abdominal segment 5" {def="Fifth most anterior segment of the abdomen."} is_a: AISM:0004287 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment relationship: has_part AISM:0004091 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! abdominal tergite V relationship: has_part AISM:0004107 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! abdominal sternite V relationship: posterior_to AISM:0004291 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment IV [Term] id: AISM:0004293 name: insect abdominal segment VI {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect abdominal segment that is posterior to the insect abdominal segment V and composed of abdominal tergite VI and abdominal sternite VI." [] {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} xref: http://flybase.org/cgi-bin/cvreport.pl?cvterm=FBbt\:00000027 "abdominal segment 6" {def="Sixth most anterior segment of the abdomen."} is_a: AISM:0004287 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment relationship: has_part AISM:0004093 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! abdominal tergite VI relationship: has_part AISM:0004108 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! abdominal sternite VI relationship: posterior_to AISM:0004292 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment V [Term] id: AISM:0004294 name: insect abdominal segment VII {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect abdominal segment that is posterior to the insect abdominal segment VI and composed of abdominal tergite VII and abdominal sternite VII." [] {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} xref: http://flybase.org/cgi-bin/cvreport.pl?cvterm=FBbt\:00000028 "abdominal segment 7" {def="Seventh most anterior segment of the abdomen."} is_a: AISM:0004287 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment relationship: has_part AISM:0004095 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! abdominal tergite VII relationship: has_part AISM:0004109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! abdominal sternite VII relationship: posterior_to AISM:0004293 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment VI [Term] id: AISM:0004295 name: insect abdominal segment VIII {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect abdominal segment that is posterior to the insect abdominal segment VII and composed of abdominal tergite VIII and abdominal sternite VIII." [] {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} xref: http://flybase.org/cgi-bin/cvreport.pl?cvterm=FBbt\:00000029 "abdominal segment 8" {def="Eigth most anterior segment of the abdomen."} is_a: AISM:0004287 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment relationship: has_part AISM:0004097 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! abdominal tergite VIII relationship: has_part AISM:0004110 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! abdominal sternite VIII relationship: posterior_to AISM:0004294 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment VII [Term] id: AISM:0004296 name: insect abdominal segment IX {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect abdominal segment that is posterior to the insect abdominal segment VIII and composed of abdominal tergite IX and abdominal sternite IX." [] {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} xref: http://flybase.org/cgi-bin/cvreport.pl?cvterm=FBbt\:00000030 "abdominal segment 9" {def="Ninth most anterior segment of the abdomen."} is_a: AISM:0004287 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment relationship: has_part AISM:0004117 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! abdominal tergite IX relationship: has_part AISM:0004119 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! abdominal sternite IX relationship: posterior_to AISM:0004295 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment VIII [Term] id: AISM:0004297 name: insect abdominal segment X {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect abdominal segment that is posterior to the insect abdominal segment IX and composed of abdominal tergite X and abdominal sternite X." [] {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} xref: http://flybase.org/cgi-bin/cvreport.pl?cvterm=FBbt\:00000031 "abdominal segment 10" {def="Tenth most anterior segment of the abdomen."} is_a: AISM:0004287 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment relationship: posterior_to AISM:0004296 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment IX [Term] id: AISM:0004298 name: insect prothoracic segment {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect body segment that corresponds to the prothorax and is posterior to the insect cephalic segment." [] {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004286 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect thoracic segment relationship: posterior_to AISM:0004285 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect cephalic segment [Term] id: AISM:0004299 name: insect mesothoracic segment {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect body segment that corresponds to the mesothorax and is posterior to the insect prothoracic segment." [] {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004286 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect thoracic segment relationship: posterior_to AISM:0004298 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect prothoracic segment [Term] id: AISM:0004300 name: insect metathoracic segment {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The insect body segment that corresponds to the metathorax and is posterior to the insect mesothoracic segment." [] {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004286 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect thoracic segment relationship: posterior_to AISM:0004299 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect mesothoracic segment [Term] id: AISM:0004301 name: gonocoxite {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Coxopodite (=valvifer, gonocoxa, gonocoxite): short basal piece of ovipositor elements of female genital segments VIII and IX.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The bilaterally paired insect sclerite of the postabdomen, attached to either the abdominal tergite VIII or IX." [] {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} synonym: "coxopodite" EXACT [] {creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Coxopodite (=valvifer, gonocoxa, gonocoxite): short basal piece of ovipositor elements of female genital segments VIII and IX.\""} is_a: AISM:0000003 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite relationship: has_characteristic PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired relationship: part_of AISM:0004056 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postabdomen property_value: IAO:0000589 "cuticle of gonocoxite" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004302 name: insect mouth {AISM:0000171="Snodgrass RE (1993) Principles of Insect Morphology. Cornell University Press, 768 pp.\n\nhttps://www.jstor.org/stable/10.7591/j.ctv1nhm1j\n\n\"Mouth. The external opening of the stomodaeum, situated in the ventral wall of the head between the labrum and the hypopharynx.\"", creation_date="2023-01-09", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The mouth that is surrounded by insect mandibles, labium, and labrum and is anterior to the hypopharynx." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883 2023-03-30", creation_date="2024-01-25"} synonym: "preoral cavity" EXACT [] {creation_date="2023-01-09", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"The preoral cavity is the space enclosed between the labrum and labium and the paired mandibles and maxillae\"", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: UBERON:0000165 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! mouth relationship: anterior_to AISM:0000093 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! hypopharynx relationship: surrounded_by AISM:0000042 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! labrum relationship: surrounded_by AISM:0000043 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect mandible relationship: surrounded_by AISM:0000087 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! labium [Term] id: AISM:0004303 name: insect gland opening def: "The orifice that is continuous with an ectodermal gland." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883 2023-03-30", creation_date="2024-01-25"} is_a: UBERON:0000161 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! orifice relationship: continuous_with AISM:0004235 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! ectodermal gland [Term] id: AISM:0004304 name: cuticular sensilla {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Sensilla are the basal functional and structural units of cuticular mechanoreceptors and chemoreceptors. They include the cuticular component (e.g., the cuticle of a seta), the sensory neuron (or neurons), the associated sheath cells with the cavities they enclose and the structures they produce\" p. 5.", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} def: "The region of cuticle that is attached to arthropod sensillum." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-10-11"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! insect region of cuticle is_a: UBERON:0000061 ! anatomical structure relationship: attaches_to UBERON:0002536 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! arthropod sensillum [Term] id: AISM:0004305 name: sensilla ampullacea {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Modified type of cuticular sensilla sunk below the external cuticular surface\"", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} def: "The cuticular sensilla that is dilated." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883 2023-03-30", creation_date="2024-01-25"} xref: http://purl.obolibrary.org/obo/HAO_0001098 "basiconic capitate peg sensillum" {def="Mushroom-shaped sensory structure on the flagellum, particularly the\nclava; sometimes called the sensilla ampullacea."} is_a: AISM:0004304 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! cuticular sensilla relationship: has_characteristic PATO:0001571 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! dilated [Term] id: AISM:0004306 name: stridulatory file {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} def: "The region of the cuticle that bears an anatomical collection composed of cuticular carinae." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} is_a: AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! insect region of cuticle relationship: has_member AISM:0000501 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! cuticular carina relationship: has_part UBERON:0034925 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! anatomical collection [Term] id: AISM:0004307 name: pretarsal seta {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} def: "The cuticular seta that is adjacent to the cuticle of the pretarsus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} is_a: AISM:0000039 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! cuticular seta relationship: adjacent_to AISM:0000047 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! pretarsus [Term] id: AISM:0004308 name: pulvillus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Pulvilli: smooth or hairy paired lateral membranous lobes below the claws\". p. 44.", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The cuticular protrusion that is part of the pretarsus, ventral to the tarsal claws." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-11-19"} is_a: AISM:0000008 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular protrusion relationship: has_characteristic PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired relationship: part_of AISM:0000047 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pretarsus relationship: ventral_to AISM:0004260 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pretarsal claw property_value: IAO:0000589 "cuticle of pulvillus" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004309 name: arolium {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Arolium: the median hollow lobe of the pretarsus. It can be completely membranous or partly sclerotized.\" p. 42.\n\"unpaired, between the claws\" p. 40.", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"} def: "The medial cuticular protrusion of the pretarsus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} property_value: IAO:0000589 "cuticle of arolium" xsd:string {creation_date="2023-04-13"} [Term] id: AISM:0004310 name: radial field of the insect wing def: "The region of the insect wing that is posterior to the costal field of the insect wing." [] {creation_date="2023-01-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004242 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-21"} ! insect wing region relationship: posterior_to AISM:0004248 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-21"} ! costal field of the insect wing [Term] id: AISM:0004311 name: cubital field of the insect wing def: "The region of the insect wing that is posterior to the medial field of the insect wing." [] {creation_date="2023-01-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004242 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-21"} ! insect wing region relationship: posterior_to AISM:0004312 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-21"} ! medial field of the insect wing [Term] id: AISM:0004312 name: medial field of the insect wing def: "The region of the insect wing that is posterior to the radial field of the insect wing." [] {creation_date="2023-01-21", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0004242 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-21"} ! insect wing region relationship: posterior_to AISM:0004310 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-21"} ! radial field of the insect wing [Term] id: AISM:0004313 name: tracheal gill {AISM:0000171="http://insecta.bio.spbu.ru/z/antidictionary/tergalii&gills.htm\n\n\"Paraspiracular tracheal gill. Paired abdominal appendage, whose trachea arises either directly from the spiracular trachea of the same abdominal segment, or from the nearest point of tracheae branching\"", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-02-05"} def: "The bilaterally paired cuticular protrusion that contains insect tracheae." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-02-05"} is_a: AISM:0000008 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-02-05"} ! cuticular protrusion relationship: has_characteristic PATO:0040024 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-02-05"} ! bilaterally paired relationship: has_part AISM:0000091 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-02-05"} ! insect trachea [Term] id: AISM:0004314 name: insect thoracic spiracle {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-02-05"} def: "The insect spiracle that is part of the insect thorax." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-02-05"} is_a: AISM:0000135 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-02-05"} ! insect spiracle relationship: part_of AISM:0000108 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-02-05"} ! insect thorax [Term] id: AISM:0004315 name: insect abdominal insect spiracle {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-02-05"} def: "The insect spiracle that is part of the insect abdomen." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-02-05"} is_a: AISM:0000135 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-02-05"} ! insect spiracle relationship: part_of AISM:0000109 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-02-05"} ! insect abdomen [Term] id: AISM:0004316 name: insect external male genitalia {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-01-12"} def: "The external male genitalia with insect cuticle and composed of phallobase, phallobasal-parameral conjunctiva, paramere (or parameres), paramero-aedeagal conjunctiva, aedeagus, and endophallus." [] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", x_1.1:creator="2024-01-12"} is_a: UBERON:0004053 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-01-12"} ! external male genitalia relationship: has_component AISM:0000174 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-01-12"} ! insect region of cuticle relationship: has_part AISM:0004062 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-01-12"} ! aedeagus relationship: has_part AISM:0004063 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-01-12"} ! endophallus relationship: has_part AISM:0004065 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-01-12"} ! phallobase relationship: has_part AISM:0004200 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-01-12"} ! paramero-aedeagal conjunctiva relationship: has_part AISM:0004201 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-01-12"} ! phallobasal-parameral conjunctiva [Term] id: AISM:0004317 name: deflexed {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} def: "A quality inhering in a bearer by virtue of the bearer's surface becoming bent or curving downward or backward." [Oxford Languages through Google.] {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} is_a: PATO:0001591 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} ! curvature [Term] id: AISM:0004318 name: antenna with 10 antennomeres {creation_date="2024-06-20", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The antenna that has scapus, pedicellus, and flagellomeres 1-8, and does not have flagellomere 9." [] {creation_date="2024-06-20", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000032 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! antenna relationship: has_part AISM:0000334 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 2 relationship: has_part AISM:0000335 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 3 relationship: has_part AISM:0000336 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 4 relationship: has_part AISM:0000337 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 5 relationship: has_part AISM:0000338 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 6 relationship: has_part AISM:0000339 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 7 relationship: has_part AISM:0000340 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-06-20"} ! flagellomere 8 [Term] id: AISM:0004319 name: antenna with 11 antennomeres {creation_date="2024-06-20", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The antenna that has scapus, pedicellus, and flagellomeres 1-9." [] {creation_date="2024-06-20", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000032 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! antenna relationship: has_part AISM:0000334 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 2 relationship: has_part AISM:0000335 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 3 relationship: has_part AISM:0000336 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 4 relationship: has_part AISM:0000337 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 5 relationship: has_part AISM:0000338 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 6 relationship: has_part AISM:0000339 {x_1.1:contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 7 relationship: has_part AISM:0000340 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-06-20"} ! flagellomere 8 [Term] id: AISM:0004320 name: empodial seta {creation_date="2024-06-20", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} def: "The cuticular seta that is adjacent to the cuticle of the empodium." [] {creation_date="2024-06-20", x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883"} is_a: AISM:0000039 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-06-20"} ! cuticular seta relationship: adjacent_to AISM:0004261 {x_1.1:contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-06-20"} ! empodium [Term] id: BFO:0000001 name: entity property_value: BFO:0000179 "entity" xsd:string property_value: BFO:0000180 "Entity" xsd:string property_value: editor_note "BFO 2 Reference: In all areas of empirical inquiry we encounter general terms of two sorts. First are general terms which refer to universals or types:animaltuberculosissurgical procedurediseaseSecond, are general terms used to refer to groups of entities which instantiate a given universal but do not correspond to the extension of any subuniversal of that universal because there is nothing intrinsic to the entities in question by virtue of which they – and only they – are counted as belonging to the given group. Examples are: animal purchased by the Emperortuberculosis diagnosed on a Wednesdaysurgical procedure performed on a patient from Stockholmperson identified as candidate for clinical trial #2056-555person who is signatory of Form 656-PPVpainting by Leonardo da VinciSuch terms, which represent what are called ‘specializations’ in [81" xsd:string property_value: editor_note "Entity doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example Werner Ceusters 'portions of reality' include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, 'How to track absolutely everything' at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/0000004", comment="per discussion with Barry Smith", seeAlso="http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf"} property_value: IAO:0000112 "Julius Caesar" xsd:string property_value: IAO:0000112 "the Second World War" xsd:string property_value: IAO:0000112 "Verdi’s Requiem" xsd:string property_value: IAO:0000112 "your body mass index" xsd:string property_value: IAO:0000600 "An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/001-001"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000002 name: continuant def: "An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts." [] is_a: BFO:0000001 ! entity disjoint_from: BFO:0000003 ! occurrent relationship: part_of BFO:0000002 {all_only="true"} ! continuant property_value: BFO:0000179 "continuant" xsd:string property_value: BFO:0000180 "Continuant" xsd:string property_value: editor_note "BFO 2 Reference: Continuant entities are entities which can be sliced to yield parts only along the spatial dimension, yielding for example the parts of your table which we call its legs, its top, its nails. ‘My desk stretches from the window to the door. It has spatial parts, and can be sliced (in space) in two. With respect to time, however, a thing is a continuant.’ [60, p. 240" xsd:string property_value: editor_note "Continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster's other portions of reality, questions are raised as to whether universals are continuants" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/0000007"} property_value: IAO:0000600 "A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/008-002"} property_value: IAO:0000601 "if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/126-001"} property_value: IAO:0000601 "if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/009-002"} property_value: IAO:0000601 "if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/011-002"} property_value: IAO:0000602 "(forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/009-002"} property_value: IAO:0000602 "(forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/126-001"} property_value: IAO:0000602 "(forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/008-002"} property_value: IAO:0000602 "(forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/011-002"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000003 name: occurrent def: "An entity that has temporal parts and that happens, unfolds or develops through time." [] is_a: BFO:0000001 ! entity relationship: part_of BFO:0000003 {all_only="true"} ! occurrent property_value: BFO:0000179 "occurrent" xsd:string property_value: BFO:0000180 "Occurrent" xsd:string property_value: editor_note "BFO 2 Reference: every occurrent that is not a temporal or spatiotemporal region is s-dependent on some independent continuant that is not a spatial region" xsd:string property_value: editor_note "BFO 2 Reference: s-dependence obtains between every process and its participants in the sense that, as a matter of necessity, this process could not have existed unless these or those participants existed also. A process may have a succession of participants at different phases of its unfolding. Thus there may be different players on the field at different times during the course of a football game; but the process which is the entire game s-depends_on all of these players nonetheless. Some temporal parts of this process will s-depend_on on only some of the players." xsd:string property_value: editor_note "Occurrent doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the sum of a process and the process boundary of another process." xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/0000006", comment="per discussion with Barry Smith"} property_value: editor_note "Simons uses different terminology for relations of occurrents to regions: Denote the spatio-temporal location of a given occurrent e by 'spn[e]' and call this region its span. We may say an occurrent is at its span, in any larger region, and covers any smaller region. Now suppose we have fixed a frame of reference so that we can speak not merely of spatio-temporal but also of spatial regions (places) and temporal regions (times). The spread of an occurrent, (relative to a frame of reference) is the space it exactly occupies, and its spell is likewise the time it exactly occupies. We write 'spr[e]' and `spl[e]' respectively for the spread and spell of e, omitting mention of the frame." xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/0000012"} property_value: IAO:0000589 "processual entity (BFO)" xsd:string property_value: IAO:0000600 "An occurrent is an entity that unfolds itself in time or it is the instantaneous boundary of such an entity (for example a beginning or an ending) or it is a temporal or spatiotemporal region which such an entity occupies_temporal_region or occupies_spatiotemporal_region. (axiom label in BFO2 Reference: [077-002])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/077-002"} property_value: IAO:0000601 "b is an occurrent entity iff b is an entity that has temporal parts. (axiom label in BFO2 Reference: [079-001])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/079-001"} property_value: IAO:0000601 "Every occurrent occupies_spatiotemporal_region some spatiotemporal region. (axiom label in BFO2 Reference: [108-001])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/108-001"} property_value: IAO:0000602 "(forall (x) (if (Occurrent x) (exists (r) (and (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion x r))))) // axiom label in BFO2 CLIF: [108-001] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/108-001"} property_value: IAO:0000602 "(forall (x) (iff (Occurrent x) (and (Entity x) (exists (y) (temporalPartOf y x))))) // axiom label in BFO2 CLIF: [079-001] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/079-001"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000004 name: independent continuant def: "A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything." [] def: "b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])" [] {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/017-002"} comment: A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything. is_a: BFO:0000002 ! continuant disjoint_from: BFO:0000020 ! specifically dependent continuant disjoint_from: BFO:0000031 ! generically dependent continuant relationship: part_of BFO:0000004 {all_only="true"} ! independent continuant property_value: BFO:0000179 "ic" xsd:string property_value: BFO:0000180 "IndependentContinuant" xsd:string property_value: IAO:0000112 "a chair" xsd:string property_value: IAO:0000112 "a heart" xsd:string property_value: IAO:0000112 "a leg" xsd:string property_value: IAO:0000112 "a molecule" xsd:string property_value: IAO:0000112 "a spatial region" xsd:string property_value: IAO:0000112 "an atom" xsd:string property_value: IAO:0000112 "an orchestra." xsd:string property_value: IAO:0000112 "an organism" xsd:string property_value: IAO:0000112 "the bottom right portion of a human torso" xsd:string property_value: IAO:0000112 "the interior of your mouth" xsd:string property_value: IAO:0000589 "anatomical entity (BFO)" xsd:string property_value: IAO:0000601 "For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/134-001"} property_value: IAO:0000601 "For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/018-002"} property_value: IAO:0000602 "(forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/018-002"} property_value: IAO:0000602 "(forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/134-001"} property_value: IAO:0000602 "(iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/017-002"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000006 name: spatial region is_a: BFO:0000141 ! immaterial entity property_value: BFO:0000179 "s-region" xsd:string property_value: BFO:0000180 "SpatialRegion" xsd:string property_value: editor_note "BFO 2 Reference: Spatial regions do not participate in processes." xsd:string property_value: editor_note "Spatial region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the union of a spatial point and a spatial line that doesn't overlap the point, or two spatial lines that intersect at a single point. In both cases the resultant spatial region is neither 0-dimensional, 1-dimensional, 2-dimensional, or 3-dimensional." xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/0000002", comment="per discussion with Barry Smith"} property_value: IAO:0000600 "A spatial region is a continuant entity that is a continuant_part_of spaceR as defined relative to some frame R. (axiom label in BFO2 Reference: [035-001])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/035-001"} property_value: IAO:0000601 "All continuant parts of spatial regions are spatial regions. (axiom label in BFO2 Reference: [036-001])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/036-001"} property_value: IAO:0000602 "(forall (x y t) (if (and (SpatialRegion x) (continuantPartOfAt y x t)) (SpatialRegion y))) // axiom label in BFO2 CLIF: [036-001] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/036-001"} property_value: IAO:0000602 "(forall (x) (if (SpatialRegion x) (Continuant x))) // axiom label in BFO2 CLIF: [035-001] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/035-001"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000009 name: two-dimensional spatial region is_a: BFO:0000006 ! spatial region property_value: BFO:0000179 "2d-s-region" xsd:string property_value: BFO:0000180 "TwoDimensionalSpatialRegion" xsd:string property_value: IAO:0000112 "an infinitely thin plane in space." xsd:string property_value: IAO:0000112 "the surface of a sphere-shaped part of space" xsd:string property_value: IAO:0000600 "A two-dimensional spatial region is a spatial region that is of two dimensions. (axiom label in BFO2 Reference: [039-001])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/039-001"} property_value: IAO:0000602 "(forall (x) (if (TwoDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [039-001] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/039-001"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000015 name: process def: "An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t." [] def: "p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])" [] {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/083-003"} comment: An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. is_a: BFO:0000003 ! occurrent property_value: BFO:0000179 "process" xsd:string property_value: BFO:0000180 "Process" xsd:string property_value: editor_note "BFO 2 Reference: The realm of occurrents is less pervasively marked by the presence of natural units than is the case in the realm of independent continuants. Thus there is here no counterpart of ‘object’. In BFO 1.0 ‘process’ served as such a counterpart. In BFO 2.0 ‘process’ is, rather, the occurrent counterpart of ‘material entity’. Those natural – as contrasted with engineered, which here means: deliberately executed – units which do exist in the realm of occurrents are typically either parasitic on the existence of natural units on the continuant side, or they are fiat in nature. Thus we can count lives; we can count football games; we can count chemical reactions performed in experiments or in chemical manufacturing. We cannot count the processes taking place, for instance, in an episode of insect mating behavior.Even where natural units are identifiable, for example cycles in a cyclical process such as the beating of a heart or an organism’s sleep/wake cycle, the processes in question form a sequence with no discontinuities (temporal gaps) of the sort that we find for instance where billiard balls or zebrafish or planets are separated by clear spatial gaps. Lives of organisms are process units, but they too unfold in a continuous series from other, prior processes such as fertilization, and they unfold in turn in continuous series of post-life processes such as post-mortem decay. Clear examples of boundaries of processes are almost always of the fiat sort (midnight, a time of death as declared in an operating theater or on a death certificate, the initiation of a state of war)" xsd:string property_value: IAO:0000112 "a process of cell-division, \\ a beating of the heart" xsd:string property_value: IAO:0000112 "a process of meiosis" xsd:string property_value: IAO:0000112 "a process of sleeping" xsd:string property_value: IAO:0000112 "the course of a disease" xsd:string property_value: IAO:0000112 "the flight of a bird" xsd:string property_value: IAO:0000112 "the life of an organism" xsd:string property_value: IAO:0000112 "your process of aging." xsd:string property_value: IAO:0000602 "(iff (Process a) (and (Occurrent a) (exists (b) (properTemporalPartOf b a)) (exists (c t) (and (MaterialEntity c) (specificallyDependsOnAt a c t))))) // axiom label in BFO2 CLIF: [083-003] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/083-003"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000016 name: disposition is_a: BFO:0000017 ! realizable entity disjoint_from: BFO:0000023 ! role property_value: BFO:0000179 "disposition" xsd:string property_value: BFO:0000180 "Disposition" xsd:string property_value: editor_note "BFO 2 Reference: Dispositions exist along a strength continuum. Weaker forms of disposition are realized in only a fraction of triggering cases. These forms occur in a significant number of cases of a similar type." xsd:string property_value: IAO:0000112 "an atom of element X has the disposition to decay to an atom of element Y" xsd:string property_value: IAO:0000112 "certain people have a predisposition to colon cancer" xsd:string property_value: IAO:0000112 "children are innately disposed to categorize objects in certain ways." xsd:string property_value: IAO:0000112 "the cell wall is disposed to filter chemicals in endocytosis and exocytosis" xsd:string property_value: IAO:0000600 "b is a disposition means: b is a realizable entity & b’s bearer is some material entity & b is such that if it ceases to exist, then its bearer is physically changed, & b’s realization occurs when and because this bearer is in some special physical circumstances, & this realization occurs in virtue of the bearer’s physical make-up. (axiom label in BFO2 Reference: [062-002])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/062-002"} property_value: IAO:0000601 "If b is a realizable entity then for all t at which b exists, b s-depends_on some material entity at t. (axiom label in BFO2 Reference: [063-002])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/063-002"} property_value: IAO:0000602 "(forall (x t) (if (and (RealizableEntity x) (existsAt x t)) (exists (y) (and (MaterialEntity y) (specificallyDepends x y t))))) // axiom label in BFO2 CLIF: [063-002] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/063-002"} property_value: IAO:0000602 "(forall (x) (if (Disposition x) (and (RealizableEntity x) (exists (y) (and (MaterialEntity y) (bearerOfAt x y t)))))) // axiom label in BFO2 CLIF: [062-002] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/062-002"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000017 name: realizable entity def: "A specifically dependent continuant that inheres in continuant entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances." [] is_a: BFO:0000020 ! specifically dependent continuant disjoint_from: BFO:0000019 ! quality relationship: part_of BFO:0000017 {all_only="true"} ! realizable entity property_value: BFO:0000179 "realizable" xsd:string property_value: BFO:0000180 "RealizableEntity" xsd:string property_value: IAO:0000112 "the disposition of this piece of metal to conduct electricity." xsd:string property_value: IAO:0000112 "the disposition of your blood to coagulate" xsd:string property_value: IAO:0000112 "the function of your reproductive organs" xsd:string property_value: IAO:0000112 "the role of being a doctor" xsd:string property_value: IAO:0000112 "the role of this boundary to delineate where Utah and Colorado meet" xsd:string property_value: IAO:0000600 "To say that b is a realizable entity is to say that b is a specifically dependent continuant that inheres in some independent continuant which is not a spatial region and is of a type instances of which are realized in processes of a correlated type. (axiom label in BFO2 Reference: [058-002])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/058-002"} property_value: IAO:0000601 "All realizable dependent continuants have independent continuants that are not spatial regions as their bearers. (axiom label in BFO2 Reference: [060-002])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/060-002"} property_value: IAO:0000602 "(forall (x t) (if (RealizableEntity x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (bearerOfAt y x t))))) // axiom label in BFO2 CLIF: [060-002] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/060-002"} property_value: IAO:0000602 "(forall (x) (if (RealizableEntity x) (and (SpecificallyDependentContinuant x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (inheresIn x y)))))) // axiom label in BFO2 CLIF: [058-002] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/058-002"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000019 name: quality namespace: bfo is_a: BFO:0000020 ! specifically dependent continuant relationship: part_of BFO:0000019 {all_only="true"} ! quality property_value: BFO:0000179 "quality" xsd:string property_value: BFO:0000180 "Quality" xsd:string property_value: IAO:0000112 "the ambient temperature of this portion of air" xsd:string property_value: IAO:0000112 "the color of a tomato" xsd:string property_value: IAO:0000112 "the length of the circumference of your waist" xsd:string property_value: IAO:0000112 "the mass of this piece of gold." xsd:string property_value: IAO:0000112 "the shape of your nose" xsd:string property_value: IAO:0000112 "the shape of your nostril" xsd:string property_value: IAO:0000600 "a quality is a specifically dependent continuant that, in contrast to roles and dispositions, does not require any further process in order to be realized. (axiom label in BFO2 Reference: [055-001])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/055-001"} property_value: IAO:0000601 "If an entity is a quality at any time that it exists, then it is a quality at every time that it exists. (axiom label in BFO2 Reference: [105-001])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/105-001"} property_value: IAO:0000602 "(forall (x) (if (exists (t) (and (existsAt x t) (Quality x))) (forall (t_1) (if (existsAt x t_1) (Quality x))))) // axiom label in BFO2 CLIF: [105-001] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/105-001"} property_value: IAO:0000602 "(forall (x) (if (Quality x) (SpecificallyDependentContinuant x))) // axiom label in BFO2 CLIF: [055-001] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/055-001"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000020 name: specifically dependent continuant def: "A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same." [] def: "b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003])" [] {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/050-003"} comment: A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same. is_a: BFO:0000002 ! continuant disjoint_from: BFO:0000031 ! generically dependent continuant relationship: part_of BFO:0000020 {all_only="true"} ! specifically dependent continuant property_value: BFO:0000179 "sdc" xsd:string property_value: BFO:0000180 "SpecificallyDependentContinuant" xsd:string property_value: editor_note "Specifically dependent continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. We're not sure what else will develop here, but for example there are questions such as what are promises, obligation, etc." xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/0000005", comment="per discussion with Barry Smith"} property_value: IAO:0000112 "of one-sided specifically dependent continuants: the mass of this tomato" xsd:string property_value: IAO:0000112 "of relational dependent continuants (multiple bearers): John’s love for Mary, the ownership relation between John and this statue, the relation of authority between John and his subordinates." xsd:string property_value: IAO:0000112 "Reciprocal specifically dependent continuants: the function of this key to open this lock and the mutually dependent disposition of this lock: to be opened by this key" xsd:string property_value: IAO:0000112 "the disposition of this fish to decay" xsd:string property_value: IAO:0000112 "the function of this heart: to pump blood" xsd:string property_value: IAO:0000112 "the mutual dependence of proton donors and acceptors in chemical reactions [79" xsd:string property_value: IAO:0000112 "the mutual dependence of the role predator and the role prey as played by two organisms in a given interaction" xsd:string property_value: IAO:0000112 "the pink color of a medium rare piece of grilled filet mignon at its center" xsd:string property_value: IAO:0000112 "the role of being a doctor" xsd:string property_value: IAO:0000112 "the shape of this hole." xsd:string property_value: IAO:0000112 "the smell of this portion of mozzarella" xsd:string property_value: IAO:0000602 "(iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/050-003"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000023 name: role def: "A realizable entity the manifestation of which brings about some result or end that is not essential to a continuant in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant in some kinds of natural, social or institutional contexts." [] is_a: BFO:0000017 ! realizable entity property_value: BFO:0000179 "role" xsd:string property_value: BFO:0000180 "Role" xsd:string property_value: editor_note "BFO 2 Reference: One major family of examples of non-rigid universals involves roles, and ontologies developed for corresponding administrative purposes may consist entirely of representatives of entities of this sort. Thus ‘professor’, defined as follows,b instance_of professor at t =Def. there is some c, c instance_of professor role & c inheres_in b at t.denotes a non-rigid universal and so also do ‘nurse’, ‘student’, ‘colonel’, ‘taxpayer’, and so forth. (These terms are all, in the jargon of philosophy, phase sortals.) By using role terms in definitions, we can create a BFO conformant treatment of such entities drawing on the fact that, while an instance of professor may be simultaneously an instance of trade union member, no instance of the type professor role is also (at any time) an instance of the type trade union member role (any more than any instance of the type color is at any time an instance of the type length).If an ontology of employment positions should be defined in terms of roles following the above pattern, this enables the ontology to do justice to the fact that individuals instantiate the corresponding universals – professor, sergeant, nurse – only during certain phases in their lives." xsd:string property_value: IAO:0000112 "John’s role of husband to Mary is dependent on Mary’s role of wife to John, and both are dependent on the object aggregate comprising John and Mary as member parts joined together through the relational quality of being married." xsd:string property_value: IAO:0000112 "the priest role" xsd:string property_value: IAO:0000112 "the role of a boundary to demarcate two neighboring administrative territories" xsd:string property_value: IAO:0000112 "the role of a building in serving as a military target" xsd:string property_value: IAO:0000112 "the role of a stone in marking a property boundary" xsd:string property_value: IAO:0000112 "the role of subject in a clinical trial" xsd:string property_value: IAO:0000112 "the student role" xsd:string property_value: IAO:0000600 "b is a role means: b is a realizable entity & b exists because there is some single bearer that is in some special physical, social, or institutional set of circumstances in which this bearer does not have to be& b is not such that, if it ceases to exist, then the physical make-up of the bearer is thereby changed. (axiom label in BFO2 Reference: [061-001])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/061-001"} property_value: IAO:0000602 "(forall (x) (if (Role x) (RealizableEntity x))) // axiom label in BFO2 CLIF: [061-001] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/061-001"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000030 name: object namespace: bfo is_a: BFO:0000040 ! material entity [Term] id: BFO:0000031 name: generically dependent continuant def: "b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001])" [] {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/074-001"} comment: A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time. is_a: BFO:0000002 ! continuant relationship: part_of BFO:0000031 {all_only="true"} ! generically dependent continuant property_value: BFO:0000179 "gdc" xsd:string property_value: BFO:0000180 "GenericallyDependentContinuant" xsd:string property_value: IAO:0000112 "The entries in your database are patterns instantiated as quality instances in your hard drive. The database itself is an aggregate of such patterns. When you create the database you create a particular instance of the generically dependent continuant type database. Each entry in the database is an instance of the generically dependent continuant type IAO: information content entity." xsd:string property_value: IAO:0000112 "the pdf file on your laptop, the pdf file that is a copy thereof on my laptop" xsd:string property_value: IAO:0000112 "the sequence of this protein molecule; the sequence that is a copy thereof in that protein molecule." xsd:string property_value: IAO:0000602 "(iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/074-001"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000034 name: function is_a: BFO:0000016 ! disposition property_value: BFO:0000179 "function" xsd:string property_value: BFO:0000180 "Function" xsd:string property_value: editor_note "BFO 2 Reference: In the past, we have distinguished two varieties of function, artifactual function and biological function. These are not asserted subtypes of BFO:function however, since the same function – for example: to pump, to transport – can exist both in artifacts and in biological entities. The asserted subtypes of function that would be needed in order to yield a separate monoheirarchy are not artifactual function, biological function, etc., but rather transporting function, pumping function, etc." xsd:string property_value: IAO:0000112 "the function of a hammer to drive in nails" xsd:string property_value: IAO:0000112 "the function of a heart pacemaker to regulate the beating of a heart through electricity" xsd:string property_value: IAO:0000112 "the function of amylase in saliva to break down starch into sugar" xsd:string property_value: IAO:0000600 "A function is a disposition that exists in virtue of the bearer’s physical make-up and this physical make-up is something the bearer possesses because it came into being, either through evolution (in the case of natural biological entities) or through intentional design (in the case of artifacts), in order to realize processes of a certain sort. (axiom label in BFO2 Reference: [064-001])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/064-001"} property_value: IAO:0000602 "(forall (x) (if (Function x) (Disposition x))) // axiom label in BFO2 CLIF: [064-001] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/064-001"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000040 name: material entity namespace: bfo def: "An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time." [] is_a: BFO:0000004 ! independent continuant disjoint_from: BFO:0000141 ! immaterial entity property_value: BFO:0000179 "material" xsd:string property_value: BFO:0000180 "MaterialEntity" xsd:string property_value: editor_note "BFO 2 Reference: Material entities (continuants) can preserve their identity even while gaining and losing material parts. Continuants are contrasted with occurrents, which unfold themselves in successive temporal parts or phases [60" xsd:string property_value: editor_note "BFO 2 Reference: Object, Fiat Object Part and Object Aggregate are not intended to be exhaustive of Material Entity. Users are invited to propose new subcategories of Material Entity." xsd:string property_value: editor_note "BFO 2 Reference: ‘Matter’ is intended to encompass both mass and energy (we will address the ontological treatment of portions of energy in a later version of BFO). A portion of matter is anything that includes elementary particles among its proper or improper parts: quarks and leptons, including electrons, as the smallest particles thus far discovered; baryons (including protons and neutrons) at a higher level of granularity; atoms and molecules at still higher levels, forming the cells, organs, organisms and other material entities studied by biologists, the portions of rock studied by geologists, the fossils studied by paleontologists, and so on.Material entities are three-dimensional entities (entities extended in three spatial dimensions), as contrasted with the processes in which they participate, which are four-dimensional entities (entities extended also along the dimension of time).According to the FMA, material entities may have immaterial entities as parts – including the entities identified below as sites; for example the interior (or ‘lumen’) of your small intestine is a part of your body. BFO 2.0 embodies a decision to follow the FMA here." xsd:string property_value: editor_note "Elucidation: An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time." xsd:string property_value: IAO:0000112 "a flame" xsd:string property_value: IAO:0000112 "a forest fire" xsd:string property_value: IAO:0000112 "a human being" xsd:string property_value: IAO:0000112 "a hurricane" xsd:string property_value: IAO:0000112 "a photon" xsd:string property_value: IAO:0000112 "a puff of smoke" xsd:string property_value: IAO:0000112 "a sea wave" xsd:string property_value: IAO:0000112 "a tornado" xsd:string property_value: IAO:0000112 "an aggregate of human beings." xsd:string property_value: IAO:0000112 "an energy wave" xsd:string property_value: IAO:0000112 "an epidemic" xsd:string property_value: IAO:0000112 "the undetached arm of a human being" xsd:string property_value: IAO:0000600 "A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/019-002"} property_value: IAO:0000601 "every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/021-002"} property_value: IAO:0000601 "Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/020-002"} property_value: IAO:0000602 "(forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/021-002"} property_value: IAO:0000602 "(forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/020-002"} property_value: IAO:0000602 "(forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/019-002"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000141 name: immaterial entity is_a: BFO:0000004 ! independent continuant property_value: BFO:0000179 "immaterial" xsd:string property_value: BFO:0000180 "ImmaterialEntity" xsd:string property_value: editor_note "BFO 2 Reference: Immaterial entities are divided into two subgroups:boundaries and sites, which bound, or are demarcated in relation, to material entities, and which can thus change location, shape and size and as their material hosts move or change shape or size (for example: your nasal passage; the hold of a ship; the boundary of Wales (which moves with the rotation of the Earth) [38, 7, 10" xsd:string property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BSPO:0000000 name: left side namespace: spatial def: "The side of an organism that is left of the sagittal plane." [BSPO:cjm] synonym: "left" EXACT [] is_a: BSPO:0000054 ! anatomical side relationship: left_of BSPO:0000007 ! right side relationship: starts_axis BSPO:0000017 ! left-right axis [Term] id: BSPO:0000001 name: upper side namespace: spatial comment: Consider merging with superior side. synonym: "upper" EXACT [] is_a: BSPO:0000054 ! anatomical side relationship: starts_axis BSPO:0000011 ! upper-lower axis [Term] id: BSPO:0000002 name: lower side namespace: spatial comment: Consider merging with inferior side. synonym: "lower" EXACT [] is_a: BSPO:0000054 ! anatomical side relationship: finishes_axis BSPO:0000011 ! upper-lower axis [Term] id: BSPO:0000005 name: anatomical surface namespace: spatial def: "A 2D surface of an anatomical continuant." [BSPO:cjm] comment: to be merged into CARO synonym: "surface" EXACT [] xref: FMA:24137 is_a: CARO:0000010 ! anatomical boundary [Term] id: BSPO:0000006 name: anatomical margin namespace: spatial def: "Fiat anatomical region extending a short distance from the boundary of an object inwards." [BSPO:cjm] synonym: "edge" EXACT [] synonym: "margin" EXACT [] is_a: BSPO:0000070 ! anatomical region [Term] id: BSPO:0000007 name: right side namespace: spatial def: "The side of an organism that is right of the sagittal plane." [BSPO:cjm, BSPO:wd] synonym: "right" EXACT [] is_a: BSPO:0000054 ! anatomical side relationship: finishes_axis BSPO:0000017 ! left-right axis [Term] id: BSPO:0000010 name: anatomical axis namespace: spatial def: "A straight line through space, intersecting an anatomical entity." [BSPO:cjm] comment: Axis directions are defined in terms of axes. xref: http://upload.wikimedia.org/wikipedia/commons/3/34/Anatomical_Directions_and_Axes.JPG is_a: CARO:0000008 ! anatomical line relationship: passes_through CARO:0000000 ! anatomical entity [Term] id: BSPO:0000011 name: upper-lower axis namespace: spatial def: "An anatomical axis determined by gravity." [BSPO:cjm] synonym: "superior-inferior axis" RELATED [] is_a: BSPO:0000010 ! anatomical axis [Term] id: BSPO:0000013 name: anterior-posterior axis namespace: spatial def: "An axis that extends through an organism from head end to opposite end of body or tail." [BSPO:cjm] comment: In sponges, AP is used to indicate the direction of movement [in larval stage] (as it is in other metazoans that move, e.g., the basal bilaterians). [PM] synonym: "A-P axis" EXACT [] synonym: "anteroposterior axis" EXACT [] synonym: "AP axis" EXACT [] synonym: "cephalocaudal axis" NARROW [http://en.wikipedia.org/wiki/Anatomical_terms_of_location] synonym: "craniocaudal axis" NARROW vertebrate [] synonym: "longitudinal axis" RELATED [] synonym: "rostral/caudal" NARROW vertebrate [] synonym: "rostrocaudal axis" NARROW vertebrate [] is_a: BSPO:0000010 ! anatomical axis intersection_of: BSPO:0000010 ! anatomical axis intersection_of: orthogonal_to BSPO:0000018 ! transverse plane relationship: approximately_perpendicular_to BSPO:0000016 ! dorsal-ventral axis relationship: orthogonal_to BSPO:0000018 ! transverse plane [Term] id: BSPO:0000015 name: proximal-distal axis namespace: spatial def: "An axis that extends from the point of attachment of a structure (proximal) to the point furthest away from the plane of attachment (distal)." [BSPO:curators, http://en.wikipedia.org/wiki/Anatomical_terms_of_location] comment: In some communities, proximal and distal are used when specifying the position of parts of elements that are contained within the body, such as gill arches or vertebral spines. In these cases, use of the classes medial-lateral axis or medial-external axis are more appropriate. synonym: "proximal/distal" EXACT [] synonym: "proximodistal" EXACT [] is_a: BSPO:0000010 ! anatomical axis [Term] id: BSPO:0000016 name: dorsal-ventral axis namespace: spatial def: "An axis that is approximately perpendicular to the anterior-posterior axis and that extends through the horizontal plane of the body." [BSPO:curators] synonym: "anterior-posterior axis" NARROW human [] synonym: "D-V axis" EXACT [] synonym: "dorsoventral axis" EXACT [] synonym: "DV axis" EXACT [] is_a: BSPO:0000010 ! anatomical axis intersection_of: BSPO:0000010 ! anatomical axis intersection_of: orthogonal_to BSPO:0000019 ! horizontal plane relationship: orthogonal_to BSPO:0000019 ! horizontal plane [Term] id: BSPO:0000017 name: left-right axis namespace: spatial def: "An axis that bisects an organism from left to right sides of body, through a sagittal plane." [BSPO:cjm] synonym: "dextro-sinister axis" EXACT [] synonym: "L-R axis" EXACT [] synonym: "left to right axis" EXACT [] synonym: "LR axis" EXACT [] synonym: "R-L axis" EXACT [] synonym: "right to left axis" EXACT [] synonym: "right-left axis" EXACT [] synonym: "RL axis" EXACT [] is_a: BSPO:0000010 ! anatomical axis intersection_of: BSPO:0000010 ! anatomical axis intersection_of: orthogonal_to BSPO:0000417 ! sagittal plane relationship: orthogonal_to BSPO:0000417 ! sagittal plane [Term] id: BSPO:0000018 name: transverse plane namespace: spatial def: "Anatomical plane that divides body into anterior and posterior parts." [BSPO:mah] synonym: "axial plane" EXACT [] synonym: "axial section" EXACT [] synonym: "cross-section" RELATED [] synonym: "transverse section" EXACT [] xref: FMA:12247 is_a: BSPO:0000400 ! anatomical plane [Term] id: BSPO:0000019 name: horizontal plane namespace: spatial def: "Anatomical plane that divides bilateral body into dorsal and ventral parts." [BSPO:mah] synonym: "coronal section" RELATED [] synonym: "frontal plane" EXACT [] synonym: "frontal section" RELATED [] synonym: "horizontal anatomical plane" EXACT [FMA:52810] synonym: "horizontal section" EXACT [] xref: FMA:52810 is_a: BSPO:0000400 ! anatomical plane [Term] id: BSPO:0000026 name: antero-dorsal region namespace: spatial def: "Anatomical region that overlaps the anterior and dorsal regions of a body or body part." [BSPO:wd] synonym: "anterodorsal region " EXACT [] is_a: BSPO:0000071 ! anterior region is_a: BSPO:0000079 ! dorsal region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000055 ! anterior side intersection_of: overlaps BSPO:0000063 ! dorsal side created_by: Melissa Haendel creation_date: 2009-06-15T01:01:38Z [Term] id: BSPO:0000027 name: antero-ventral region namespace: spatial def: "Anatomical region that overlaps the anterior and ventral regions of a body or body part." [BSPO:wd] synonym: "anteroventral region " EXACT [] is_a: BSPO:0000071 ! anterior region is_a: BSPO:0000084 ! ventral region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000055 ! anterior side intersection_of: overlaps BSPO:0000068 ! ventral side created_by: Melissa Haendel creation_date: 2009-06-15T01:04:59Z [Term] id: BSPO:0000028 name: postero-lateral region namespace: spatial def: "Anatomical region that overlaps the posterior and lateral regions of the body or body part." [BSPO:wd] synonym: "posterolateral region" EXACT [] is_a: BSPO:0000072 ! posterior region is_a: BSPO:0000082 ! lateral region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000056 ! posterior side intersection_of: overlaps BSPO:0000066 ! lateral side created_by: Melissa Haendel creation_date: 2009-06-15T01:06:01Z [Term] id: BSPO:0000029 name: antero-lateral region namespace: spatial def: "Anatomical region that overlaps the anterior and lateral regions of a body or body part." [BSPO:wd] synonym: "anterolateral region" EXACT [] is_a: BSPO:0000071 ! anterior region is_a: BSPO:0000082 ! lateral region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000055 ! anterior side intersection_of: overlaps BSPO:0000066 ! lateral side created_by: Melissa Haendel creation_date: 2009-06-15T01:07:18Z [Term] id: BSPO:0000030 name: postero-dorsal region namespace: spatial def: "Anatomical region that overlaps the posterior and dorsal regions of the body or body part." [BSPO:wd] synonym: "posterodorsal region" EXACT [] is_a: BSPO:0000072 ! posterior region is_a: BSPO:0000079 ! dorsal region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000056 ! posterior side intersection_of: overlaps BSPO:0000063 ! dorsal side created_by: Melissa Haendel creation_date: 2009-06-15T01:08:13Z [Term] id: BSPO:0000031 name: upper region namespace: spatial is_a: BSPO:0000070 ! anatomical region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000001 ! upper side relationship: overlaps BSPO:0000001 ! upper side [Term] id: BSPO:0000032 name: lower region namespace: spatial is_a: BSPO:0000070 ! anatomical region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000002 ! lower side relationship: overlaps BSPO:0000002 ! lower side [Term] id: BSPO:0000035 name: postero-ventral region namespace: spatial def: "Anatomical region that overlaps the posterior and ventral regions of a body or body part." [BSPO:wd] synonym: "posteroventral region" EXACT [] is_a: BSPO:0000072 ! posterior region is_a: BSPO:0000084 ! ventral region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000056 ! posterior side intersection_of: overlaps BSPO:0000068 ! ventral side created_by: Melissa Haendel creation_date: 2009-06-15T01:08:38Z [Term] id: BSPO:0000042 name: antero-medial margin namespace: spatial def: "Anatomical margin that is located on the antero-medial region of the body or body part." [BSPO:wd] synonym: "anteromedial margin" EXACT [] is_a: BSPO:0000050 ! antero-medial region is_a: BSPO:0000671 ! anterior margin is_a: BSPO:0000683 ! medial margin intersection_of: BSPO:0000006 ! anatomical margin intersection_of: overlaps BSPO:0000055 ! anterior side intersection_of: overlaps BSPO:0000067 ! medial side created_by: Melissa Haendel creation_date: 2009-09-10T08:49:57Z [Term] id: BSPO:0000045 name: antero-lateral margin namespace: spatial def: "Anatomical margin that is located on the antero-lateral region of the body or body part." [BSPO:wd] synonym: "anterolateral margin" EXACT [] is_a: BSPO:0000029 ! antero-lateral region is_a: BSPO:0000671 ! anterior margin is_a: BSPO:0000682 ! lateral margin intersection_of: BSPO:0000006 ! anatomical margin intersection_of: overlaps BSPO:0000055 ! anterior side intersection_of: overlaps BSPO:0000066 ! lateral side created_by: Melissa Haendel creation_date: 2009-09-10T08:50:37Z [Term] id: BSPO:0000046 name: postero-medial margin namespace: spatial def: "Anatomical margin that is located on the postero-medial region of the body or body part." [BSPO:wd] synonym: "posteromedial margin" EXACT [] is_a: BSPO:0000064 ! postero-medial region is_a: BSPO:0000672 ! posterior margin is_a: BSPO:0000683 ! medial margin intersection_of: BSPO:0000006 ! anatomical margin intersection_of: overlaps BSPO:0000056 ! posterior side intersection_of: overlaps BSPO:0000067 ! medial side created_by: Melissa Haendel creation_date: 2009-09-10T08:51:07Z [Term] id: BSPO:0000047 name: postero-lateral margin namespace: spatial def: "Anatomical margin that is located on the postero-lateral region of the body or body part." [BSPO:wd] synonym: "posterolateral margin" EXACT [] is_a: BSPO:0000028 ! postero-lateral region is_a: BSPO:0000672 ! posterior margin is_a: BSPO:0000682 ! lateral margin intersection_of: BSPO:0000006 ! anatomical margin intersection_of: overlaps BSPO:0000056 ! posterior side intersection_of: overlaps BSPO:0000066 ! lateral side created_by: Melissa Haendel creation_date: 2009-09-10T08:51:42Z [Term] id: BSPO:0000048 name: dorso-medial margin namespace: spatial def: "Anatomical margin that is located on the dorso-medial region of the body or body part." [BSPO:wd] synonym: "dorso-medial margin" EXACT [] is_a: BSPO:0000069 ! dorso-medial region is_a: BSPO:0000679 ! dorsal margin is_a: BSPO:0000683 ! medial margin intersection_of: BSPO:0000006 ! anatomical margin intersection_of: overlaps BSPO:0000063 ! dorsal side intersection_of: overlaps BSPO:0000067 ! medial side created_by: Melissa Haendel creation_date: 2009-09-10T08:52:04Z [Term] id: BSPO:0000049 name: ventro-medial margin namespace: spatial def: "Anatomical margin that is located on the ventro-medial region of the body or body part." [BSPO:wd] synonym: "ventromedial margin" EXACT [] is_a: BSPO:0000112 ! ventro-medial region is_a: BSPO:0000683 ! medial margin is_a: BSPO:0000684 ! ventral margin intersection_of: BSPO:0000006 ! anatomical margin intersection_of: overlaps BSPO:0000067 ! medial side intersection_of: overlaps BSPO:0000068 ! ventral side created_by: Melissa Haendel creation_date: 2009-09-10T08:52:48Z [Term] id: BSPO:0000050 name: antero-medial region namespace: spatial def: "Anatomical region that overlaps the anterior and medial regions of the body or body part." [BSPO:wd] synonym: "anteromedial region" EXACT [] is_a: BSPO:0000071 ! anterior region is_a: BSPO:0000083 ! medial region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000055 ! anterior side intersection_of: overlaps BSPO:0000067 ! medial side created_by: Melissa Haendel creation_date: 2009-09-10T08:55:32Z [Term] id: BSPO:0000054 name: anatomical side namespace: spatial def: "An anatomical region bounded by a plane perpendicular to an axis through the middle." [BSPO:cjm] xref: FBql:00005841 is_a: BSPO:0000070 ! anatomical region [Term] id: BSPO:0000055 name: anterior side namespace: spatial def: "An anatomical region that is the entire part of an anatomical structure anterior to a transverse plane and bounded on one side by the same transverse plane." [BSPO:RW] synonym: "anterior" EXACT [] synonym: "rostral" EXACT [] xref: FBcv:0000053 xref: FBql:00005848 is_a: BSPO:0000054 ! anatomical side relationship: anterior_to BSPO:0000056 ! posterior side relationship: opposite_to BSPO:0000056 ! posterior side relationship: starts_axis BSPO:0000013 ! anterior-posterior axis [Term] id: BSPO:0000056 name: posterior side namespace: spatial def: "An anatomical region that is the entire part of an anatomical structure posterior to a transverse plane and bounded on one side by the same transverse plane." [BSPO:RW, BSPO:wd] synonym: "caudal" NARROW vertebrate [] synonym: "posterior" EXACT [] xref: FBcv:0000065 xref: FBql:00005849 is_a: BSPO:0000054 ! anatomical side relationship: finishes_axis BSPO:0000013 ! anterior-posterior axis relationship: posterior_to BSPO:0000055 ! anterior side [Term] id: BSPO:0000061 name: proximal side namespace: spatial synonym: "proximal" EXACT [] xref: FBcv:0000066 xref: FBql:00005852 is_a: BSPO:0000054 ! anatomical side relationship: opposite_to BSPO:0000062 ! distal side relationship: starts_axis BSPO:0000015 ! proximal-distal axis [Term] id: BSPO:0000062 name: distal side namespace: spatial def: "Anatomical side that is distally located on an organism or structure." [BSPO:wd] synonym: "distal" EXACT [] xref: FBcv:0000058 xref: FBql:00005853 is_a: BSPO:0000054 ! anatomical side relationship: distal_to BSPO:0000061 ! proximal side relationship: finishes_axis BSPO:0000015 ! proximal-distal axis [Term] id: BSPO:0000063 name: dorsal side namespace: spatial def: "An anatomical region that is the entire part of an anatomical structure dorsal to a horizontal plane and bounded on one side by the same transverse plane." [BSPO:wd] synonym: "dorsal" EXACT [] xref: FBcv:0000059 xref: FBql:00005842 is_a: BSPO:0000054 ! anatomical side relationship: dorsal_to BSPO:0000066 ! lateral side relationship: opposite_to BSPO:0000068 ! ventral side relationship: starts_axis BSPO:0000016 ! dorsal-ventral axis [Term] id: BSPO:0000064 name: postero-medial region namespace: spatial def: "Anatomical region that overlaps the posterior and medial regions of the body or body part." [BSPO:wd] synonym: "posteromedial region" EXACT [] is_a: BSPO:0000072 ! posterior region is_a: BSPO:0000083 ! medial region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000056 ! posterior side intersection_of: overlaps BSPO:0000067 ! medial side created_by: Melissa Haendel creation_date: 2009-09-10T08:56:39Z [Term] id: BSPO:0000066 name: lateral side namespace: spatial synonym: "lateral" EXACT [] xref: FBcv:0000063 xref: FBql:00005844 is_a: BSPO:0000054 ! anatomical side [Term] id: BSPO:0000067 name: medial side namespace: spatial comment: a point in the centre of the organism (where the left-right axis intersects the midsagittal plane) synonym: "medial" EXACT [] xref: FBcv:0000064 xref: FBql:00005847 is_a: BSPO:0000054 ! anatomical side [Term] id: BSPO:0000068 name: ventral side namespace: spatial def: "An anatomical region that is the entire part of an anatomical structure ventral to a horizontal plane and bounded on one side by the same horizontal plane." [BSPO:RW, BSPO:wd] synonym: "ventral" EXACT [] xref: FBcv:0000070 xref: FBql:00005843 is_a: BSPO:0000054 ! anatomical side relationship: finishes_axis BSPO:0000016 ! dorsal-ventral axis [Term] id: BSPO:0000069 name: dorso-medial region namespace: spatial def: "Anatomical region that overlaps the dorsal and medial regions of the body or body part." [BSPO:wd] synonym: "dorsomedial region" EXACT [] is_a: BSPO:0000079 ! dorsal region is_a: BSPO:0000083 ! medial region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000063 ! dorsal side intersection_of: overlaps BSPO:0000067 ! medial side created_by: Melissa Haendel creation_date: 2009-09-10T08:57:22Z [Term] id: BSPO:0000070 name: anatomical region namespace: spatial def: "A 3D region in space without well-defined compartmental boundaries; for example, the dorsal region of an ectoderm." [BSPO:cjm] comment: to be merged into CARO xref: FBql:00005841 is_a: CARO:0000003 ! connected anatomical structure [Term] id: BSPO:0000071 name: anterior region namespace: spatial def: "Anatomical region anteriorly located on the body or body part." [BSPO:wd] xref: FBql:00005848 is_a: BSPO:0000070 ! anatomical region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000055 ! anterior side relationship: overlaps BSPO:0000055 ! anterior side [Term] id: BSPO:0000072 name: posterior region namespace: spatial def: "Anatomical region posteriorly located on the body or body part." [BSPO:wd] xref: FBql:00005849 is_a: BSPO:0000070 ! anatomical region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000056 ! posterior side relationship: overlaps BSPO:0000056 ! posterior side [Term] id: BSPO:0000077 name: proximal region namespace: spatial def: "Anatomical region proximally located on the body or body part." [BSPO:wd] xref: FBql:00005852 is_a: BSPO:0000070 ! anatomical region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000061 ! proximal side relationship: overlaps BSPO:0000061 ! proximal side [Term] id: BSPO:0000078 name: distal region namespace: spatial def: "Anatomical region distally located on the body or body part." [BSPO:wd] xref: FBql:00005853 is_a: BSPO:0000070 ! anatomical region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000062 ! distal side relationship: overlaps BSPO:0000062 ! distal side [Term] id: BSPO:0000079 name: dorsal region namespace: spatial def: "Anatomical region dorsally located on the body or body part." [BSPO:wd] xref: FBql:00005842 is_a: BSPO:0000070 ! anatomical region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000063 ! dorsal side relationship: overlaps BSPO:0000063 ! dorsal side [Term] id: BSPO:0000080 name: dorso-lateral region namespace: spatial def: "Anatomical region that overlaps the dorsal and lateral regions of a body or body part." [BSPO:wd] synonym: "dorsolateral region" EXACT [] xref: FBql:00005845 is_a: BSPO:0000079 ! dorsal region is_a: BSPO:0000082 ! lateral region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000063 ! dorsal side intersection_of: overlaps BSPO:0000066 ! lateral side [Term] id: BSPO:0000082 name: lateral region namespace: spatial def: "Anatomical region laterally located on the body or body part." [BSPO:wd] xref: FBql:00005844 is_a: BSPO:0000070 ! anatomical region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000066 ! lateral side relationship: overlaps BSPO:0000066 ! lateral side [Term] id: BSPO:0000083 name: medial region namespace: spatial def: "Anatomical region medially located on the body or body part." [BSPO:wd] xref: FBql:00005847 is_a: BSPO:0000070 ! anatomical region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000067 ! medial side relationship: overlaps BSPO:0000067 ! medial side [Term] id: BSPO:0000084 name: ventral region namespace: spatial def: "Anatomical region ventrally located on the body or body part." [BSPO:wd] xref: FBql:00005843 is_a: BSPO:0000070 ! anatomical region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000068 ! ventral side relationship: overlaps BSPO:0000068 ! ventral side [Term] id: BSPO:0000085 name: ventro-lateral region namespace: spatial def: "Anatomical region that overlaps the ventral and lateral regions of a body or body part." [BSPO:wd] comment: This is an example of a composition of two axis positions. synonym: "ventrolateral region" EXACT [] xref: FBql:00005846 is_a: BSPO:0000082 ! lateral region is_a: BSPO:0000084 ! ventral region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000066 ! lateral side intersection_of: overlaps BSPO:0000068 ! ventral side [Term] id: BSPO:0000112 name: ventro-medial region namespace: spatial def: "The region corresponding to the ventral region of the entity, towards the midline." [BSPO:wd] synonym: "medioventral region" EXACT [] synonym: "ventromedial region" EXACT [] is_a: BSPO:0000083 ! medial region is_a: BSPO:0000084 ! ventral region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000067 ! medial side intersection_of: overlaps BSPO:0000068 ! ventral side created_by: Melissa Haendel creation_date: 2009-09-10T08:57:54Z [Term] id: BSPO:0000371 name: anterior surface namespace: spatial def: "Anatomical surface that is located on the anterior side of the body or body part." [BSPO:wd] xref: FBql:00005848 is_a: BSPO:0000005 ! anatomical surface intersection_of: BSPO:0000005 ! anatomical surface intersection_of: surface_of BSPO:0000055 ! anterior side relationship: surface_of BSPO:0000055 ! anterior side [Term] id: BSPO:0000372 name: posterior surface namespace: spatial def: "Anatomical surface that is located on the posterior side of the body or body part." [BSPO:wd] xref: FBql:00005849 is_a: BSPO:0000005 ! anatomical surface intersection_of: BSPO:0000005 ! anatomical surface intersection_of: surface_of BSPO:0000056 ! posterior side relationship: surface_of BSPO:0000056 ! posterior side [Term] id: BSPO:0000377 name: internal side name: proximal surface namespace: spatial def: "Anatomical surface that is located on the proximal side of the body or body part." [BSPO:wd] xref: FBql:00005852 is_a: BSPO:0000005 ! anatomical surface intersection_of: BSPO:0000005 ! anatomical surface intersection_of: surface_of BSPO:0000061 ! proximal side relationship: opposite_to BSPO:0000378 ! distal surface relationship: surface_of BSPO:0000061 ! proximal side [Term] id: BSPO:0000378 name: distal surface name: external side namespace: spatial def: "Anatomical surface that is located on the distal side of the body or body part." [BSPO:wd] xref: FBql:00005853 is_a: BSPO:0000005 ! anatomical surface intersection_of: BSPO:0000005 ! anatomical surface intersection_of: surface_of BSPO:0000062 ! distal side relationship: opposite_to BSPO:0000377 ! internal side relationship: surface_of BSPO:0000062 ! distal side [Term] id: BSPO:0000379 name: dorsal surface namespace: spatial def: "Anatomical surface that located on the dorsal side of the body or body part." [BSPO:wd] xref: FBql:00005842 is_a: BSPO:0000005 ! anatomical surface intersection_of: BSPO:0000005 ! anatomical surface intersection_of: surface_of BSPO:0000063 ! dorsal side relationship: surface_of BSPO:0000063 ! dorsal side [Term] id: BSPO:0000382 name: lateral surface namespace: spatial def: "Anatomical surface that located on the lateral side of the body or body part." [BSPO:wd] xref: FBql:00005844 is_a: BSPO:0000005 ! anatomical surface intersection_of: BSPO:0000005 ! anatomical surface intersection_of: surface_of BSPO:0000066 ! lateral side relationship: surface_of BSPO:0000066 ! lateral side [Term] id: BSPO:0000383 name: medial surface namespace: spatial def: "Anatomical surface that located on the medial side of the body or body part." [BSPO:wd] xref: FBql:00005847 is_a: BSPO:0000005 ! anatomical surface intersection_of: BSPO:0000005 ! anatomical surface intersection_of: surface_of BSPO:0000067 ! medial side relationship: surface_of BSPO:0000067 ! medial side [Term] id: BSPO:0000384 name: ventral surface namespace: spatial def: "Anatomical surface that is located on the ventral side of the body or body part." [BSPO:wd] xref: FBql:00005843 is_a: BSPO:0000005 ! anatomical surface intersection_of: BSPO:0000005 ! anatomical surface intersection_of: surface_of BSPO:0000068 ! ventral side relationship: surface_of BSPO:0000068 ! ventral side [Term] id: BSPO:0000400 name: anatomical plane namespace: spatial def: "A flat 2D plane intersecting an anatomical continuant, dividing it into two adjacent portions." [BSPO:cjm] comment: These anatomical sections are applicable to most bilaterally symmetrical animals, but bipedal animals such as humans have more complex usage of these terms. For example, in post-embryonic humans a coronal plane is vertical and a transverse plane is horizontal, but for embryos and quadrupeds a coronal plane is horizontal and a transverse plane is vertical. synonym: "anatomical cross-section" EXACT [] synonym: "anatomical section" EXACT [] synonym: "cross-section" RELATED [] synonym: "plane" EXACT [] synonym: "section" EXACT [] xref: FMA:242982 is_a: CARO:0000010 ! anatomical boundary [Term] id: BSPO:0000417 name: sagittal plane namespace: spatial def: "Anatomical plane that divides a bilateral body into left and right parts, not necessarily of even size." [BSPO:cjm, BSPO:DOS, BSPO:mah] synonym: "left/right plane" EXACT [] synonym: "median plane" EXACT [] synonym: "sagittal section" EXACT [] xref: FMA:11361 is_a: BSPO:0000010 ! anatomical axis is_a: BSPO:0000400 ! anatomical plane intersection_of: BSPO:0000400 ! anatomical plane intersection_of: BSPO:0001102 BSPO:0000013 ! parallel to anterior-posterior axis intersection_of: BSPO:0001102 BSPO:0000016 ! parallel to dorsal-ventral axis intersection_of: orthogonal_to BSPO:0000017 ! left-right axis relationship: BSPO:0001102 BSPO:0000013 ! parallel to anterior-posterior axis relationship: BSPO:0001102 BSPO:0000016 ! parallel to dorsal-ventral axis relationship: orthogonal_to BSPO:0000017 ! left-right axis [Term] id: BSPO:0000671 name: anterior margin namespace: spatial def: "Anatomical margin that is located on the anterior side of a body or body part." [BSPO:wd] is_a: BSPO:0000006 ! anatomical margin is_a: BSPO:0000071 ! anterior region intersection_of: BSPO:0000006 ! anatomical margin intersection_of: overlaps BSPO:0000055 ! anterior side [Term] id: BSPO:0000672 name: posterior margin namespace: spatial def: "Anatomical margin that is located on the posterior side of the body or body part." [BSPO:wd] is_a: BSPO:0000006 ! anatomical margin is_a: BSPO:0000072 ! posterior region intersection_of: BSPO:0000006 ! anatomical margin intersection_of: overlaps BSPO:0000056 ! posterior side [Term] id: BSPO:0000677 name: proximal margin namespace: spatial def: "Anatomical margin that is located on the proximal region of the body or body part." [BSPO:wd] is_a: BSPO:0000006 ! anatomical margin is_a: BSPO:0000077 ! proximal region intersection_of: BSPO:0000006 ! anatomical margin intersection_of: overlaps BSPO:0000061 ! proximal side [Term] id: BSPO:0000678 name: distal margin namespace: spatial def: "Anatomical margin that is located on the distal side of the body or body part." [BSPO:wd] is_a: BSPO:0000006 ! anatomical margin is_a: BSPO:0000078 ! distal region intersection_of: BSPO:0000006 ! anatomical margin intersection_of: overlaps BSPO:0000062 ! distal side [Term] id: BSPO:0000679 name: dorsal margin namespace: spatial def: "Anatomical margin that is located on the dorsal side of body or body part." [BSPO:wd] is_a: BSPO:0000006 ! anatomical margin is_a: BSPO:0000079 ! dorsal region intersection_of: BSPO:0000006 ! anatomical margin intersection_of: overlaps BSPO:0000063 ! dorsal side [Term] id: BSPO:0000680 name: dorso-lateral margin namespace: spatial def: "Anatomical margin that is located on the dorso-lateral region of the body or body part." [BSPO:wd] synonym: "dorsolateral margin" EXACT [] is_a: BSPO:0000080 ! dorso-lateral region is_a: BSPO:0000679 ! dorsal margin is_a: BSPO:0000682 ! lateral margin intersection_of: BSPO:0000006 ! anatomical margin intersection_of: overlaps BSPO:0000063 ! dorsal side intersection_of: overlaps BSPO:0000066 ! lateral side [Term] id: BSPO:0000682 name: lateral margin namespace: spatial def: "Anatomical margin that is located on the lateral side of the body or body part." [BSPO:wd] is_a: BSPO:0000006 ! anatomical margin is_a: BSPO:0000082 ! lateral region intersection_of: BSPO:0000006 ! anatomical margin intersection_of: overlaps BSPO:0000066 ! lateral side [Term] id: BSPO:0000683 name: medial margin namespace: spatial def: "Anatomical margin that is located on the medial side of the body or body part." [BSPO:wd] is_a: BSPO:0000006 ! anatomical margin is_a: BSPO:0000083 ! medial region intersection_of: BSPO:0000006 ! anatomical margin intersection_of: overlaps BSPO:0000067 ! medial side [Term] id: BSPO:0000684 name: ventral margin namespace: spatial def: "Anatomical margin that is located on the ventral side of the body or body part." [BSPO:wd] is_a: BSPO:0000006 ! anatomical margin is_a: BSPO:0000084 ! ventral region intersection_of: BSPO:0000006 ! anatomical margin intersection_of: overlaps BSPO:0000068 ! ventral side [Term] id: BSPO:0000685 name: ventro-lateral margin namespace: spatial def: "Anatomical margin that is located on the ventro-lateral region of the body or body part." [BSPO:wd] comment: This is an example of a composition of two axis positions synonym: "ventrolateral margin" EXACT [] is_a: BSPO:0000085 ! ventro-lateral region is_a: BSPO:0000682 ! lateral margin is_a: BSPO:0000684 ! ventral margin intersection_of: BSPO:0000006 ! anatomical margin intersection_of: overlaps BSPO:0000066 ! lateral side intersection_of: overlaps BSPO:0000068 ! ventral side [Term] id: BSPO:0000686 name: antero-dorsal margin namespace: spatial def: "Anatomical margin that is located on the antero-dorso region of the body or body part." [BSPO:wd] synonym: "anterodorsal margin" EXACT [] is_a: BSPO:0000026 ! antero-dorsal region is_a: BSPO:0000671 ! anterior margin is_a: BSPO:0000679 ! dorsal margin intersection_of: BSPO:0000006 ! anatomical margin intersection_of: overlaps BSPO:0000055 ! anterior side intersection_of: overlaps BSPO:0000063 ! dorsal side [Term] id: BSPO:0000687 name: postero-dorsal margin namespace: spatial def: "Anatomical margin that is located on the postero-dorsal region of the body or body part." [BSPO:wd] synonym: "posterodorsal margin" EXACT [] is_a: BSPO:0000030 ! postero-dorsal region is_a: BSPO:0000672 ! posterior margin is_a: BSPO:0000679 ! dorsal margin intersection_of: BSPO:0000006 ! anatomical margin intersection_of: overlaps BSPO:0000056 ! posterior side intersection_of: overlaps BSPO:0000063 ! dorsal side [Term] id: BSPO:0000688 name: antero-ventral margin namespace: spatial def: "Anatomical margin that is located on the antero-ventral region of the body or body part." [BSPO:wd] synonym: "anteroventral margin" EXACT [] is_a: BSPO:0000027 ! antero-ventral region is_a: BSPO:0000671 ! anterior margin is_a: BSPO:0000684 ! ventral margin intersection_of: BSPO:0000006 ! anatomical margin intersection_of: overlaps BSPO:0000055 ! anterior side intersection_of: overlaps BSPO:0000068 ! ventral side [Term] id: BSPO:0000689 name: postero-ventral margin namespace: spatial def: "Anatomical margin that is located on the postero-ventral region of the body or body part." [BSPO:wd] synonym: "posteroventral margin" EXACT [] is_a: BSPO:0000035 ! postero-ventral region is_a: BSPO:0000672 ! posterior margin is_a: BSPO:0000684 ! ventral margin intersection_of: BSPO:0000006 ! anatomical margin intersection_of: overlaps BSPO:0000056 ! posterior side intersection_of: overlaps BSPO:0000068 ! ventral side [Term] id: CARO:0000000 name: anatomical entity namespace: spatial def: "A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex. Or, a substance produced by a cellular organism with granularity above the level of a protein complex." [CAROC:Brownsville2014] def: "Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species." [CARO:MAH] comment: Following BFO, material anatomical entities may have immaterial parts (the lumen of your stomach is part of your stomach). The granularity limit follows the limits set by the Gene Ontology on the granularity limit for GO:cellular_component. Note that substances produced by an organism (sweat, feaces, urine) do not need to be part of an organism to qualify as an anatomical structure. is_a: BFO:0000004 ! independent continuant [Term] id: CARO:0000003 name: anatomical structure name: connected anatomical structure namespace: spatial def: "Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome." [CC:DOS] comment: Note that the definition does not say 'generated exclusively by the co-ordinated expression of the organism's own genome', so this is still valid for cases where normal morphogenesis requires the actions of a facultative symbiont, or some looser dependency such as the a requirement for the presence of gut flora for normal gut development. is_a: CARO:0000006 ! material anatomical entity [Term] id: CARO:0000006 name: material anatomical entity namespace: spatial def: "An anatomical entity that has mass." [CC:DOS] is_a: CARO:0000000 ! anatomical entity disjoint_from: CARO:0000007 ! immaterial anatomical entity [Term] id: CARO:0000007 name: immaterial anatomical entity namespace: spatial def: "An anatomical entity that has no mass." [CC:DOS] def: "Anatomical entity that has no mass." [] is_a: BFO:0000141 ! immaterial entity is_a: CARO:0000000 ! anatomical entity [Term] id: CARO:0000008 name: anatomical line namespace: spatial def: "A one dimensional, immaterial anatomical entity." [CC:DOS] is_a: CARO:0000007 ! immaterial anatomical entity [Term] id: CARO:0000010 name: anatomical boundary namespace: spatial def: "A non-material anatomical entity of two dimensions. Anatomical boundaries are contiguous structures." [CC:DOS] is_a: CARO:0000007 ! immaterial anatomical entity [Term] id: CHEBI:10545 name: electron namespace: chebi_ontology def: "Elementary particle not affected by the strong force having a spin 1/2, a negative elementary charge and a rest mass of 0.000548579903(13) u, or 0.51099906(15) MeV." [] subset: 3_STAR synonym: "beta" RELATED [IUPAC] synonym: "beta(-)" RELATED [ChEBI] synonym: "beta-particle" RELATED [IUPAC] synonym: "e" RELATED [IUPAC] synonym: "e(-)" RELATED [UniProt] synonym: "e-" RELATED [KEGG_COMPOUND] synonym: "electron" EXACT [KEGG_COMPOUND] synonym: "electron" EXACT IUPAC_NAME [IUPAC] synonym: "electron" EXACT [ChEBI] synonym: "Elektron" RELATED [ChEBI] synonym: "negatron" RELATED [IUPAC] xref: KEGG:C05359 xref: PMID:21614077 {source="Europe PMC"} xref: Wikipedia:Electron is_a: CHEBI:36338 ! lepton property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "0.000548579903" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "0.0" xsd:string [Term] id: CHEBI:131927 name: dicarboxylic acids and O-substituted derivatives namespace: chebi_ontology def: "A class of carbonyl compound encompassing dicarboxylic acids and any derivatives obtained by substitution of either one or both of the carboxy hydrogens." [] subset: 3_STAR synonym: "dicarboxylic acids and derivatives" RELATED [ChEBI] is_a: CHEBI:36586 ! carbonyl compound [Term] id: CHEBI:132153 name: hyaluronate namespace: chebi_ontology def: "A carbohydrate acid derivative anion obtained by deprotonation of the carboxy groups of hyaluronic acid; major species at pH 7.3." [] subset: 3_STAR synonym: "hyaluronan" RELATED [UniProt] synonym: "hyaluronate polyanion" RELATED [ChEBI] is_a: CHEBI:61469 ! polyanionic polymer is_a: CHEBI:63551 ! carbohydrate acid derivative anion relationship: is_conjugate_base_of CHEBI:16336 ! hyaluronic acid property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "(C14H20NO11)n.H2O" xsd:string [Term] id: CHEBI:136889 name: 5beta steroid namespace: chebi_ontology def: "Any steroid that has beta-configuration at position 5." [] subset: 3_STAR synonym: "5beta steroids" RELATED [ChEBI] synonym: "5beta-steroid" RELATED [ChEBI] synonym: "5beta-steroids" RELATED [ChEBI] is_a: CHEBI:35341 ! steroid [Term] id: CHEBI:138103 name: inorganic acid namespace: chebi_ontology def: "A Bronsted acid derived from one or more inorganic compounds. Inorganic acids (also known as mineral acids) form hydrons and conjugate base ions when dissolved in water." [] subset: 3_STAR synonym: "inorganic acids" RELATED [ChEBI] synonym: "mineral acid" RELATED [ChEBI] synonym: "mineral acids" RELATED [ChEBI] xref: Wikipedia:Mineral_acid is_a: CHEBI:39141 ! Bronsted acid [Term] id: CHEBI:138366 name: bile acids namespace: chebi_ontology def: "Any member of a group of hydroxy steroids occuring in bile, where they are present as the sodium salts of their amides with glycine or taurine. In mammals bile acids almost invariably have 5beta-configuration, while in lower vertebrates, some bile acids, known as allo-bile acids, have 5alpha-configuration." [] subset: 3_STAR is_a: CHEBI:25384 ! monocarboxylic acid is_a: CHEBI:35350 ! hydroxy steroid is_a: CHEBI:36078 ! cholanoid [Term] id: CHEBI:138675 name: gas molecular entity namespace: chebi_ontology def: "Any main group molecular entity that is gaseous at standard temperature and pressure (STP; 0degreeC and 100 kPa)." [] subset: 3_STAR synonym: "gas molecular entities" RELATED [ChEBI] synonym: "gaseous molecular entities" RELATED [ChEBI] synonym: "gaseous molecular entity" RELATED [ChEBI] xref: Wikipedia:https\://en.wikipedia.org/wiki/Gas is_a: CHEBI:33579 ! main group molecular entity [Term] id: CHEBI:13941 name: carbamate namespace: chebi_ontology subset: 3_STAR synonym: "Carbamat" RELATED [ChEBI] synonym: "carbamate" EXACT [UniProt] synonym: "carbamate" EXACT IUPAC_NAME [IUPAC] synonym: "carbamate ion" RELATED [ChemIDplus] synonym: "carbamic acid, ion(1-)" RELATED [ChemIDplus] synonym: "Karbamat" RELATED [ChEBI] xref: Beilstein:3903503 {source="Beilstein"} xref: CAS:302-11-4 {source="ChemIDplus"} xref: Gmelin:239604 {source="Gmelin"} is_a: CHEBI:37022 ! amino-acid anion relationship: is_conjugate_base_of CHEBI:28616 ! carbamic acid property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CH2NO2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/CH3NO2/c2-1(3)4/h2H2,(H,3,4)/p-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "KXDHJXZQYSOELW-UHFFFAOYSA-M" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "60.03212" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "60.00910" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "NC([O-])=O" xsd:string [Term] id: CHEBI:142163 name: 24G7 epitope namespace: chebi_ontology def: "An antigenic epitope recognized by an anti-bilirubin monoclonal antibody designated 24G7. A substructure of bilirubin IXalpha, it is the region containing the oxo group at C-1, the methyl group at C-2, C-(4, 5, 6, 9), and N-21 and -22." [] subset: 3_STAR is_a: CHEBI:24433 ! group relationship: has_role CHEBI:53000 ! epitope property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C7H6N2O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "134.136" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "134.04801" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "C(=CC(NC(=*)*)=*)(NC(C(C)=*)=O)*" xsd:string [Term] id: CHEBI:15339 name: acceptor namespace: chebi_ontology alt_id: CHEBI:13699 alt_id: CHEBI:2377 def: "A molecular entity that can accept an electron, a pair of electrons, an atom or a group from another molecular entity." [] subset: 3_STAR synonym: "A" RELATED [KEGG_COMPOUND] synonym: "accepteur" RELATED [ChEBI] synonym: "Acceptor" EXACT [KEGG_COMPOUND] synonym: "Akzeptor" RELATED [ChEBI] synonym: "Hydrogen-acceptor" RELATED [KEGG_COMPOUND] synonym: "Oxidized donor" RELATED [KEGG_COMPOUND] xref: KEGG:C00028 xref: KEGG:C16722 is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:15355 name: acetylcholine namespace: chebi_ontology alt_id: CHEBI:12686 alt_id: CHEBI:13715 alt_id: CHEBI:22197 alt_id: CHEBI:2416 alt_id: CHEBI:40559 def: "Actylcholine is an ester of acetic acid and choline, which acts as a neurotransmitter." [] subset: 3_STAR synonym: "2-acetyloxy-N,N,N-trimethylethanaminium" EXACT IUPAC_NAME [IUPAC] synonym: "ACETYLCHOLINE" EXACT [PDBeChem] synonym: "Acetylcholine" EXACT [KEGG_COMPOUND] synonym: "acetylcholine" EXACT [UniProt] synonym: "ACh" RELATED [ChemIDplus] synonym: "Azetylcholin" RELATED [ChEBI] synonym: "choline acetate" RELATED [ChemIDplus] synonym: "O-Acetylcholine" RELATED [KEGG_COMPOUND] xref: Beilstein:1764436 {source="ChemIDplus"} xref: CAS:51-84-3 {source="KEGG COMPOUND"} xref: CAS:51-84-3 {source="ChemIDplus"} xref: Drug_Central:65 {source="DrugCentral"} xref: DrugBank:DB03128 xref: Gmelin:326108 {source="Gmelin"} xref: KEGG:C01996 xref: LINCS:LSM-5888 xref: PDBeChem:ACH xref: PMID:14764638 {source="Europe PMC"} xref: PMID:15014918 {source="Europe PMC"} xref: PMID:15231705 {source="Europe PMC"} xref: PMID:15361288 {source="Europe PMC"} xref: PMID:18050502 {source="Europe PMC"} xref: PMID:18407448 {source="Europe PMC"} xref: PMID:19255787 {source="Europe PMC"} xref: PMID:20963497 {source="Europe PMC"} xref: PMID:21130809 {source="Europe PMC"} xref: PMID:21246223 {source="Europe PMC"} xref: PMID:21545631 {source="Europe PMC"} xref: PMID:21601579 {source="Europe PMC"} xref: Wikipedia:Acetylcholine is_a: CHEBI:35287 ! acylcholine is_a: CHEBI:47622 ! acetate ester relationship: has_role CHEBI:24621 ! hormone relationship: has_role CHEBI:25512 ! neurotransmitter relationship: has_role CHEBI:35620 ! vasodilator agent relationship: has_role CHEBI:38325 ! muscarinic agonist relationship: has_role CHEBI:75771 ! mouse metabolite relationship: has_role CHEBI:77746 ! human metabolite property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C7H16NO2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C7H16NO2/c1-7(9)10-6-5-8(2,3)4/h5-6H2,1-4H3/q+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "OIPILFWXSMYKGL-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "146.20748" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "146.11756" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CC(=O)OCC[N+](C)(C)C" xsd:string [Term] id: CHEBI:15366 name: acetic acid namespace: chebi_ontology alt_id: CHEBI:22169 alt_id: CHEBI:2387 alt_id: CHEBI:40486 def: "A simple monocarboxylic acid containing two carbons." [] subset: 3_STAR synonym: "ACETIC ACID" EXACT [PDBeChem] synonym: "Acetic acid" EXACT [KEGG_COMPOUND] synonym: "acetic acid" EXACT IUPAC_NAME [IUPAC] synonym: "acide acetique" RELATED [ChemIDplus] synonym: "AcOH" RELATED [ChEBI] synonym: "CH3-COOH" RELATED [IUPAC] synonym: "CH3CO2H" RELATED [ChEBI] synonym: "E 260" RELATED [ChEBI] synonym: "E-260" RELATED [ChEBI] synonym: "E260" RELATED [ChEBI] synonym: "Essigsaeure" RELATED [ChEBI] synonym: "Ethanoic acid" RELATED [KEGG_COMPOUND] synonym: "ethoic acid" RELATED [ChEBI] synonym: "Ethylic acid" RELATED [ChemIDplus] synonym: "HOAc" RELATED [ChEBI] synonym: "INS No. 260" RELATED [ChEBI] synonym: "MeCO2H" RELATED [ChEBI] synonym: "MeCOOH" RELATED [ChEBI] synonym: "Methanecarboxylic acid" RELATED [ChemIDplus] xref: Beilstein:506007 {source="Beilstein"} xref: CAS:64-19-7 {source="ChemIDplus"} xref: CAS:64-19-7 {source="NIST Chemistry WebBook"} xref: CAS:64-19-7 {source="KEGG COMPOUND"} xref: Drug_Central:4211 {source="DrugCentral"} xref: Gmelin:1380 {source="Gmelin"} xref: HMDB:HMDB0000042 xref: KEGG:C00033 xref: KEGG:D00010 xref: KNApSAcK:C00001176 xref: LIPID_MAPS_instance:LMFA01010002 {source="LIPID MAPS"} xref: MetaCyc:ACET xref: PDBeChem:ACT xref: PDBeChem:ACY xref: PMID:12005138 {source="Europe PMC"} xref: PMID:15107950 {source="Europe PMC"} xref: PMID:16630552 {source="Europe PMC"} xref: PMID:16774200 {source="Europe PMC"} xref: PMID:17190852 {source="Europe PMC"} xref: PMID:19416101 {source="Europe PMC"} xref: PMID:19469536 {source="Europe PMC"} xref: PMID:22153255 {source="Europe PMC"} xref: PMID:22173419 {source="Europe PMC"} xref: PPDB:1333 xref: Reaxys:506007 {source="Reaxys"} xref: Wikipedia:Acetic_acid is_a: CHEBI:25384 ! monocarboxylic acid relationship: has_role CHEBI:48356 ! protic solvent relationship: has_role CHEBI:64049 ! food acidity regulator relationship: has_role CHEBI:65256 ! antimicrobial food preservative relationship: has_role CHEBI:83056 ! Daphnia magna metabolite relationship: is_conjugate_acid_of CHEBI:30089 ! acetate property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H4O2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QTBSBXVTEAMEQO-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "60.05200" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "60.02113" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CC(O)=O" xsd:string [Term] id: CHEBI:15379 name: dioxygen namespace: chebi_ontology alt_id: CHEBI:10745 alt_id: CHEBI:13416 alt_id: CHEBI:23833 alt_id: CHEBI:25366 alt_id: CHEBI:30491 alt_id: CHEBI:44742 alt_id: CHEBI:7860 subset: 3_STAR synonym: "[OO]" RELATED [MolBase] synonym: "dioxygen" EXACT IUPAC_NAME [IUPAC] synonym: "dioxygene" RELATED [ChEBI] synonym: "Disauerstoff" RELATED [ChEBI] synonym: "E 948" RELATED [ChEBI] synonym: "E-948" RELATED [ChEBI] synonym: "E948" RELATED [ChEBI] synonym: "molecular oxygen" RELATED [ChEBI] synonym: "O2" RELATED [UniProt] synonym: "O2" RELATED [IUPAC] synonym: "O2" RELATED [KEGG_COMPOUND] synonym: "Oxygen" RELATED [KEGG_COMPOUND] synonym: "OXYGEN MOLECULE" RELATED [PDBeChem] xref: CAS:7782-44-7 {source="NIST Chemistry WebBook"} xref: CAS:7782-44-7 {source="ChemIDplus"} xref: CAS:7782-44-7 {source="KEGG COMPOUND"} xref: Gmelin:485 {source="Gmelin"} xref: HMDB:HMDB0001377 xref: KEGG:C00007 xref: KEGG:D00003 xref: MetaCyc:OXYGEN-MOLECULE xref: MolBase:750 xref: PDBeChem:OXY xref: PMID:10906528 {source="Europe PMC"} xref: PMID:16977326 {source="Europe PMC"} xref: PMID:18210929 {source="Europe PMC"} xref: PMID:18638417 {source="Europe PMC"} xref: PMID:19840863 {source="Europe PMC"} xref: PMID:7710549 {source="Europe PMC"} xref: PMID:9463773 {source="Europe PMC"} xref: Wikipedia:Oxygen is_a: CHEBI:138675 ! gas molecular entity is_a: CHEBI:25362 ! elemental molecule is_a: CHEBI:33263 ! diatomic oxygen relationship: has_role CHEBI:27027 ! micronutrient relationship: has_role CHEBI:33893 ! reagent relationship: has_role CHEBI:35472 ! anti-inflammatory drug relationship: has_role CHEBI:63248 ! oxidising agent relationship: has_role CHEBI:75772 ! Saccharomyces cerevisiae metabolite relationship: has_role CHEBI:77746 ! human metabolite relationship: has_role CHEBI:77974 ! food packaging gas relationship: is_conjugate_base_of CHEBI:29793 ! hydridodioxygen(1+) property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "O2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/O2/c1-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "MYMOFIZGZYHOMD-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "31.998" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "31.98983" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "O=O" xsd:string [Term] id: CHEBI:15693 name: aldose namespace: chebi_ontology alt_id: CHEBI:13755 alt_id: CHEBI:22305 alt_id: CHEBI:2561 def: "Aldehydic parent sugars (polyhydroxy aldehydes H[CH(OH)]nC(=O)H, n >= 2) and their intramolecular hemiacetals." [] subset: 3_STAR synonym: "Aldose" EXACT [KEGG_COMPOUND] synonym: "aldoses" RELATED [ChEBI] synonym: "an aldose" RELATED [UniProt] xref: KEGG:C01370 xref: Wikipedia:Aldose is_a: CHEBI:35381 ! monosaccharide property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H4O2(CH2O)n" xsd:string [Term] id: CHEBI:15841 name: polypeptide namespace: chebi_ontology alt_id: CHEBI:14860 alt_id: CHEBI:8314 def: "A peptide containing ten or more amino acid residues." [] subset: 3_STAR synonym: "polipeptido" RELATED [ChEBI] synonym: "Polypeptid" RELATED [ChEBI] synonym: "Polypeptide" EXACT [KEGG_COMPOUND] synonym: "polypeptides" EXACT IUPAC_NAME [IUPAC] xref: KEGG:C00403 is_a: CHEBI:16670 ! peptide is_a: CHEBI:33839 ! macromolecule property_value: http://purl.obolibrary.org/obo/chebi/formula "C4H6N2O3R2(C2H2NOR)n" xsd:string [Term] id: CHEBI:15986 name: polynucleotide namespace: chebi_ontology alt_id: CHEBI:13672 alt_id: CHEBI:14859 alt_id: CHEBI:8312 def: "A nucleobase-containing molecular entity with a polymeric structure comprised of a linear sequence of 13 or more nucleotide residues." [] subset: 3_STAR synonym: "Polynucleotide" EXACT [KEGG_COMPOUND] synonym: "polynucleotides" RELATED [ChEBI] xref: KEGG:C00419 is_a: CHEBI:33695 ! information biomacromolecule is_a: CHEBI:61120 ! nucleobase-containing molecular entity relationship: has_part CHEBI:50319 ! nucleotide residue property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "(C5H8O6PR)n.C10H17O10PR2" xsd:string [Term] id: CHEBI:16134 name: ammonia namespace: chebi_ontology alt_id: CHEBI:13405 alt_id: CHEBI:13406 alt_id: CHEBI:13407 alt_id: CHEBI:13771 alt_id: CHEBI:22533 alt_id: CHEBI:44269 alt_id: CHEBI:44284 alt_id: CHEBI:44404 alt_id: CHEBI:7434 def: "An azane that consists of a single nitrogen atom covelently bonded to three hydrogen atoms." [] subset: 3_STAR synonym: "[NH3]" RELATED [MolBase] synonym: "AMMONIA" EXACT [PDBeChem] synonym: "Ammonia" EXACT [KEGG_COMPOUND] synonym: "ammonia" EXACT IUPAC_NAME [IUPAC] synonym: "ammoniac" RELATED [ChEBI] synonym: "Ammoniak" RELATED [ChemIDplus] synonym: "amoniaco" RELATED [ChEBI] synonym: "azane" EXACT IUPAC_NAME [IUPAC] synonym: "NH3" RELATED [KEGG_COMPOUND] synonym: "NH3" RELATED [UniProt] synonym: "NH3" RELATED [IUPAC] synonym: "R-717" RELATED [ChEBI] synonym: "spirit of hartshorn" RELATED [ChemIDplus] xref: Beilstein:3587154 {source="Beilstein"} xref: CAS:7664-41-7 {source="ChemIDplus"} xref: CAS:7664-41-7 {source="NIST Chemistry WebBook"} xref: CAS:7664-41-7 {source="KEGG COMPOUND"} xref: Drug_Central:4625 {source="DrugCentral"} xref: Gmelin:79 {source="Gmelin"} xref: HMDB:HMDB0000051 xref: KEGG:C00014 xref: KEGG:D02916 xref: KNApSAcK:C00007267 xref: MetaCyc:AMMONIA xref: MolBase:930 xref: PDBeChem:NH3 xref: PMID:110589 {source="Europe PMC"} xref: PMID:11139349 {source="Europe PMC"} xref: PMID:11540049 {source="Europe PMC"} xref: PMID:11746427 {source="Europe PMC"} xref: PMID:11783653 {source="Europe PMC"} xref: PMID:13753780 {source="Europe PMC"} xref: PMID:14663195 {source="Europe PMC"} xref: PMID:15092448 {source="Europe PMC"} xref: PMID:15094021 {source="Europe PMC"} xref: PMID:15554424 {source="Europe PMC"} xref: PMID:15969015 {source="Europe PMC"} xref: PMID:16008360 {source="Europe PMC"} xref: PMID:16050680 {source="Europe PMC"} xref: PMID:16348008 {source="Europe PMC"} xref: PMID:16349403 {source="Europe PMC"} xref: PMID:16614889 {source="Europe PMC"} xref: PMID:16664306 {source="Europe PMC"} xref: PMID:16842901 {source="Europe PMC"} xref: PMID:17025297 {source="Europe PMC"} xref: PMID:17439666 {source="Europe PMC"} xref: PMID:17569513 {source="Europe PMC"} xref: PMID:17737668 {source="Europe PMC"} xref: PMID:18670398 {source="Europe PMC"} xref: PMID:22002069 {source="Europe PMC"} xref: PMID:22081570 {source="Europe PMC"} xref: PMID:22088435 {source="Europe PMC"} xref: PMID:22100291 {source="Europe PMC"} xref: PMID:22130175 {source="Europe PMC"} xref: PMID:22150211 {source="Europe PMC"} xref: PMID:22240068 {source="Europe PMC"} xref: PMID:22290316 {source="Europe PMC"} xref: PMID:22342082 {source="Europe PMC"} xref: PMID:22385337 {source="Europe PMC"} xref: PMID:22443779 {source="Europe PMC"} xref: PMID:22560242 {source="Europe PMC"} xref: Reaxys:3587154 {source="Reaxys"} xref: Wikipedia:Ammonia is_a: CHEBI:138675 ! gas molecular entity is_a: CHEBI:35107 ! azane is_a: CHEBI:37176 ! mononuclear parent hydride relationship: has_role CHEBI:50910 ! neurotoxin relationship: has_role CHEBI:59740 ! nucleophilic reagent relationship: has_role CHEBI:75771 ! mouse metabolite relationship: has_role CHEBI:77941 ! EC 3.5.1.4 (amidase) inhibitor relationship: has_role CHEBI:78433 ! refrigerant relationship: is_conjugate_acid_of CHEBI:29337 ! azanide relationship: is_conjugate_base_of CHEBI:28938 ! ammonium property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "H3N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H3N/h1H3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QGZKDVFQNNGYKY-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "17.03056" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "17.02655" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]N([H])[H]" xsd:string [Term] id: CHEBI:16189 name: sulfate namespace: chebi_ontology alt_id: CHEBI:15135 alt_id: CHEBI:45687 alt_id: CHEBI:9335 def: "A sulfur oxoanion obtained by deprotonation of both OH groups of sulfuric acid." [] subset: 3_STAR synonym: "[SO4](2-)" RELATED [IUPAC] synonym: "SO4(2-)" RELATED [IUPAC] synonym: "Sulfate" EXACT [KEGG_COMPOUND] synonym: "sulfate" EXACT [UniProt] synonym: "sulfate" EXACT IUPAC_NAME [IUPAC] synonym: "Sulfate anion(2-)" RELATED [HMDB] synonym: "Sulfate dianion" RELATED [HMDB] synonym: "SULFATE ION" RELATED [PDBeChem] synonym: "Sulfate(2-)" RELATED [HMDB] synonym: "Sulfuric acid ion(2-)" RELATED [HMDB] synonym: "sulphate" RELATED [ChEBI] synonym: "sulphate ion" RELATED [ChEBI] synonym: "tetraoxidosulfate(2-)" EXACT IUPAC_NAME [IUPAC] synonym: "tetraoxosulfate(2-)" EXACT IUPAC_NAME [IUPAC] synonym: "tetraoxosulfate(VI)" EXACT IUPAC_NAME [IUPAC] xref: Beilstein:3648446 {source="Beilstein"} xref: CAS:14808-79-8 {source="ChemIDplus"} xref: CAS:14808-79-8 {source="NIST Chemistry WebBook"} xref: Gmelin:2120 {source="Gmelin"} xref: HMDB:HMDB0001448 xref: KEGG:C00059 xref: KEGG:D05963 xref: MetaCyc:SULFATE xref: PDBeChem:SO4 xref: PMID:11200094 {source="Europe PMC"} xref: PMID:11452993 {source="Europe PMC"} xref: PMID:11581495 {source="Europe PMC"} xref: PMID:11798107 {source="Europe PMC"} xref: PMID:12166931 {source="Europe PMC"} xref: PMID:12668033 {source="Europe PMC"} xref: PMID:14597181 {source="Europe PMC"} xref: PMID:15093386 {source="Europe PMC"} xref: PMID:15984785 {source="Europe PMC"} xref: PMID:16186560 {source="Europe PMC"} xref: PMID:16345535 {source="Europe PMC"} xref: PMID:16347366 {source="Europe PMC"} xref: PMID:16348007 {source="Europe PMC"} xref: PMID:16483812 {source="Europe PMC"} xref: PMID:16534979 {source="Europe PMC"} xref: PMID:16656509 {source="Europe PMC"} xref: PMID:16742508 {source="Europe PMC"} xref: PMID:16742518 {source="Europe PMC"} xref: PMID:17120760 {source="Europe PMC"} xref: PMID:17420092 {source="Europe PMC"} xref: PMID:17439666 {source="Europe PMC"} xref: PMID:17709180 {source="Europe PMC"} xref: PMID:18398178 {source="Europe PMC"} xref: PMID:18815700 {source="Europe PMC"} xref: PMID:18846414 {source="Europe PMC"} xref: PMID:19047345 {source="Europe PMC"} xref: PMID:19244483 {source="Europe PMC"} xref: PMID:19544990 {source="Europe PMC"} xref: PMID:19628332 {source="Europe PMC"} xref: PMID:19812358 {source="Europe PMC"} xref: PMID:30398859 {source="Europe PMC"} xref: Reaxys:3648446 {source="Reaxys"} xref: Wikipedia:Sulfate is_a: CHEBI:33482 ! sulfur oxoanion is_a: CHEBI:48154 ! sulfur oxide is_a: CHEBI:79388 ! divalent inorganic anion relationship: has_role CHEBI:23357 ! cofactor relationship: has_role CHEBI:75772 ! Saccharomyces cerevisiae metabolite relationship: has_role CHEBI:77746 ! human metabolite relationship: is_conjugate_base_of CHEBI:45696 ! hydrogensulfate property_value: http://purl.obolibrary.org/obo/chebi/charge "-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "O4S" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QAOWNCQODCNURD-UHFFFAOYSA-L" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "96.06360" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "95.95283" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]S([O-])(=O)=O" xsd:string [Term] id: CHEBI:16336 name: hyaluronic acid namespace: chebi_ontology alt_id: CHEBI:14412 alt_id: CHEBI:24622 alt_id: CHEBI:24623 alt_id: CHEBI:5772 def: "A mucopolysaccharide composed of N-acetylglucosamine and glucuronic acid subunits. It is found in the connective tissues of vertebrates. A principal constituent of the extracellular matrix (ECM), it mediates the growth and metastasis of tumour cells." [] subset: 3_STAR synonym: "[beta-D-glucopyranuronosyl-(1->3)-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1->4)]n" RELATED [ChEBI] synonym: "[beta-N-Acetyl-D-glucosaminyl(1,4)beta-D-glucuronosyl(1,3)]n" RELATED [KEGG_COMPOUND] synonym: "acide hyaluronique" RELATED [ChEBI] synonym: "acido hialuronico" RELATED [ChEBI] synonym: "hyaluronan" RELATED [ChEBI] synonym: "Hyaluronic acid" EXACT [KEGG_COMPOUND] synonym: "Hyaluronsaeure" RELATED [ChEBI] xref: Beilstein:8538277 {source="Beilstein"} xref: CAS:9004-61-9 {source="KEGG COMPOUND"} xref: CAS:9004-61-9 {source="ChemIDplus"} xref: HMDB:HMDB0010366 xref: KEGG:C00518 xref: KEGG:D08043 xref: KEGG:G10505 xref: PMID:11122186 {source="Europe PMC"} xref: PMID:18056362 {source="Europe PMC"} xref: PMID:18290544 {source="Europe PMC"} xref: Reaxys:8187837 {source="Reaxys"} xref: Wikipedia:Hyaluronan is_a: CHEBI:37395 ! mucopolysaccharide is_a: CHEBI:72813 ! exopolysaccharide relationship: has_role CHEBI:77746 ! human metabolite relationship: is_conjugate_acid_of CHEBI:132153 ! hyaluronate property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "(C14H21NO12)n" xsd:string [Term] id: CHEBI:16541 name: protein polypeptide chain namespace: chebi_ontology alt_id: CHEBI:8526 def: "A naturally occurring polypeptide synthesized at the ribosome." [] subset: 3_STAR synonym: "a protein" RELATED [UniProt] synonym: "polypeptide chain" RELATED [ChEBI] synonym: "Protein" RELATED [KEGG_COMPOUND] synonym: "protein polypeptide chains" RELATED [ChEBI] xref: KEGG:C00017 is_a: CHEBI:15841 ! polypeptide relationship: has_part CHEBI:33700 ! proteinogenic amino-acid residue [Term] id: CHEBI:16646 name: carbohydrate namespace: chebi_ontology alt_id: CHEBI:15131 alt_id: CHEBI:23008 alt_id: CHEBI:9318 def: "Any member of the class of organooxygen compounds that is a polyhydroxy-aldehyde or -ketone or a lactol resulting from their intramolecular condensation (monosaccharides); substances derived from these by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom; and polymeric products arising by intermolecular acetal formation between two or more such molecules (disaccharides, polysaccharides and oligosaccharides). Carbohydrates contain only carbon, hydrogen and oxygen atoms; prior to any oxidation or reduction, most have the empirical formula Cm(H2O)n. Compounds obtained from carbohydrates by substitution, etc., are known as carbohydrate derivatives and may contain other elements. Cyclitols are generally not regarded as carbohydrates." [] subset: 3_STAR synonym: "a carbohydrate" RELATED [UniProt] synonym: "carbohidrato" RELATED [IUPAC] synonym: "carbohidratos" RELATED [IUPAC] synonym: "carbohydrate" EXACT IUPAC_NAME [IUPAC] synonym: "carbohydrates" EXACT IUPAC_NAME [IUPAC] synonym: "glucide" RELATED [ChEBI] synonym: "glucides" RELATED [ChEBI] synonym: "glucido" RELATED [ChEBI] synonym: "glucidos" RELATED [ChEBI] synonym: "hydrates de carbone" RELATED [ChEBI] synonym: "Kohlenhydrat" RELATED [ChEBI] synonym: "Kohlenhydrate" RELATED [ChEBI] synonym: "saccharide" RELATED [IUPAC] synonym: "saccharides" RELATED [IUPAC] synonym: "saccharidum" RELATED [ChEBI] xref: Wikipedia:Carbohydrate is_a: CHEBI:78616 ! carbohydrates and carbohydrate derivatives [Term] id: CHEBI:16670 name: peptide namespace: chebi_ontology alt_id: CHEBI:14753 alt_id: CHEBI:25906 alt_id: CHEBI:7990 def: "Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from alpha-amino acids, but it includes those derived from any amino carboxylic acid. X = OH, OR, NH2, NHR, etc." [] subset: 3_STAR synonym: "Peptid" RELATED [ChEBI] synonym: "Peptide" EXACT [KEGG_COMPOUND] synonym: "peptides" EXACT IUPAC_NAME [IUPAC] synonym: "peptido" RELATED [ChEBI] synonym: "peptidos" RELATED [ChEBI] xref: KEGG:C00012 is_a: CHEBI:37622 ! carboxamide is_a: CHEBI:50047 ! organic amino compound relationship: has_part CHEBI:33708 ! amino-acid residue relationship: is_tautomer_of CHEBI:60466 ! peptide zwitterion property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "(C2H2NOR)nC2H3NOR" xsd:string [Term] id: CHEBI:166902 name: noradrenaline(1+) namespace: chebi_ontology subset: 2_STAR synonym: "noradrenaline" RELATED [UniProt] is_a: CHEBI:25697 ! organic cation is_a: CHEBI:35274 ! ammonium ion derivative relationship: is_conjugate_acid_of CHEBI:33569 ! noradrenaline property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C8H12NO3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/p+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "SFLSHLFXELFNJZ-UHFFFAOYSA-O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "170.187" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "170.08117" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "C1=CC(=CC(=C1O)O)C(C[NH3+])O" xsd:string [Term] id: CHEBI:167559 name: glycan namespace: chebi_ontology def: "Any oligosaccharide, polysaccharide or their derivatives consisting of monosaccharides or monosaccharide derivatives linked by glycosidic bonds. See also http://www.ontobee.org/ontology/GNO?iri=http://purl.obolibrary.org/obo/GNO_00000001." [] subset: 3_STAR synonym: "glycans" RELATED [ChEBI] is_a: CHEBI:78616 ! carbohydrates and carbohydrate derivatives [Term] id: CHEBI:16765 name: tryptamine namespace: chebi_ontology alt_id: CHEBI:15274 alt_id: CHEBI:27161 alt_id: CHEBI:46157 alt_id: CHEBI:9767 def: "An aminoalkylindole consisting of indole having a 2-aminoethyl group at the 3-position." [] subset: 3_STAR synonym: "1H-indole-3-ethanamine" RELATED [NIST_Chemistry_WebBook] synonym: "2-(1H-INDOL-3-YL)ETHANAMINE" RELATED [PDBeChem] synonym: "2-(1H-indol-3-yl)ethanamine" EXACT IUPAC_NAME [IUPAC] synonym: "2-(3-indolyl)ethylamine" RELATED [ChemIDplus] synonym: "3-(2-Aminoethyl)indole" RELATED [KEGG_COMPOUND] synonym: "Tryptamine" EXACT [KEGG_COMPOUND] xref: Beilstein:125513 {source="Beilstein"} xref: CAS:61-54-1 {source="ChemIDplus"} xref: CAS:61-54-1 {source="NIST Chemistry WebBook"} xref: CAS:61-54-1 {source="KEGG COMPOUND"} xref: DrugBank:DB08653 xref: Gmelin:603448 {source="Gmelin"} xref: HMDB:HMDB0000303 xref: KEGG:C00398 xref: KNApSAcK:C00001434 xref: MetaCyc:TRYPTAMINE xref: PDBeChem:TSS xref: PMID:16126914 {source="Europe PMC"} xref: PMID:22770225 {source="Europe PMC"} xref: PMID:24345948 {source="Europe PMC"} xref: PMID:24558969 {source="Europe PMC"} xref: Reaxys:125513 {source="Reaxys"} xref: Wikipedia:Tryptamine is_a: CHEBI:27162 ! tryptamines is_a: CHEBI:38631 ! aminoalkylindole is_a: CHEBI:38958 ! indole alkaloid is_a: CHEBI:64365 ! aralkylamino compound relationship: has_role CHEBI:75771 ! mouse metabolite relationship: has_role CHEBI:76924 ! plant metabolite relationship: has_role CHEBI:77746 ! human metabolite relationship: is_conjugate_base_of CHEBI:57887 ! tryptaminium property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C10H12N2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "APJYDQYYACXCRM-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "160.21570" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "160.10005" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "NCCc1c[nH]c2ccccc12" xsd:string [Term] id: CHEBI:16990 name: bilirubin IXalpha namespace: chebi_ontology alt_id: CHEBI:13898 alt_id: CHEBI:22870 alt_id: CHEBI:3099 def: "A member of the class of biladienes that is a linear tetrapyrrole with the dipyrrole units being of both exovinyl and endovinyl type. A product of heme degradation, it is produced in the reticuloendothelial system by the reduction of biliverdin and transported to the liver as a complex with serum albumin." [] subset: 3_STAR synonym: "1,10,19,22,23,24-hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinylbiline-8,12-dipropionic acid" RELATED [ChemIDplus] synonym: "2,17-diethenyl-1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo-21H-biline-8,12-dipropanoic acid" RELATED [ChemIDplus] synonym: "2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-1,10,19,22,23,24-hexahydro-21H-biline-8,12-dipropanoic acid" RELATED [IUPAC] synonym: "3,18-diethenyl-2,7,13,17-tetramethyl-1,19-dioxo-1,10,19,22,23,24-hexahydro-21H-biline-8,12-dipropanoic acid" EXACT IUPAC_NAME [IUPAC] synonym: "8,12-bis(2-carboxyethyl)-2,7,13,17-tetramethyl-3,18-divinylbiladiene-ac-1,19(21H,24H)-dione" RELATED [JCBN] synonym: "Bilirubin" RELATED [KEGG_COMPOUND] synonym: "bilirubin" EXACT IUPAC_NAME [IUPAC] synonym: "bilirubin(Z,Z)" RELATED [ChEBI] synonym: "bilirubin-IXalpha" RELATED [ChEBI] xref: Beilstein:74376 {source="Beilstein"} xref: CAS:635-65-4 {source="KEGG COMPOUND"} xref: CAS:635-65-4 {source="ChemIDplus"} xref: Gmelin:411033 {source="Gmelin"} xref: HMDB:HMDB0000054 xref: KEGG:C00486 xref: KNApSAcK:C00029828 xref: MetaCyc:BILIRUBIN xref: PDBeChem:BLR xref: PMID:12799017 {source="Europe PMC"} xref: PMID:18442622 {source="Europe PMC"} xref: PMID:23763371 {source="Europe PMC"} xref: PMID:23768684 {source="Europe PMC"} xref: PMID:30224965 {source="Europe PMC"} xref: PMID:8605219 {source="Europe PMC"} xref: PMID:9587403 {source="Europe PMC"} xref: Reaxys:74376 {source="Reaxys"} xref: Wikipedia:Bilirubin is_a: CHEBI:35692 ! dicarboxylic acid is_a: CHEBI:36735 ! biladienes relationship: has_part CHEBI:142163 ! 24G7 epitope relationship: has_role CHEBI:22586 ! antioxidant relationship: has_role CHEBI:75771 ! mouse metabolite relationship: has_role CHEBI:77746 ! human metabolite relationship: is_conjugate_acid_of CHEBI:57977 ! bilirubin(2-) property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C33H36N4O6" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C33H36N4O6/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26/h7-8,13-14,34-35H,1-2,9-12,15H2,3-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41)/b26-13-,27-14-" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "BPYKTIZUTYGOLE-IFADSCNNSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "584.673" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "584.26348" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CC1=C(C=C)\\C(NC1=O)=C\\C1=C(C)C(CCC(O)=O)=C(CC2=C(CCC(O)=O)C(C)=C(N2)\\C=C2/NC(=O)C(C=C)=C2C)N1" xsd:string [Term] id: CHEBI:16991 name: deoxyribonucleic acid namespace: chebi_ontology alt_id: CHEBI:13302 alt_id: CHEBI:21123 alt_id: CHEBI:33698 alt_id: CHEBI:4291 def: "High molecular weight, linear polymers, composed of nucleotides containing deoxyribose and linked by phosphodiester bonds; DNA contain the genetic information of organisms." [] subset: 3_STAR synonym: "(Deoxyribonucleotide)m" RELATED [KEGG_COMPOUND] synonym: "(Deoxyribonucleotide)n" RELATED [KEGG_COMPOUND] synonym: "(Deoxyribonucleotide)n+m" RELATED [KEGG_COMPOUND] synonym: "Deoxyribonucleic acid" EXACT [KEGG_COMPOUND] synonym: "deoxyribonucleic acids" EXACT IUPAC_NAME [IUPAC] synonym: "deoxyribonucleic acids" RELATED [ChEBI] synonym: "Desoxyribonukleinsaeure" RELATED [ChEBI] synonym: "desoxyribose nucleic acid" RELATED [ChemIDplus] synonym: "DNA" RELATED [UniProt] synonym: "DNA" RELATED [KEGG_COMPOUND] synonym: "DNA" RELATED [IUPAC] synonym: "DNAn" RELATED [KEGG_COMPOUND] synonym: "DNAn+1" RELATED [KEGG_COMPOUND] synonym: "DNS" RELATED [ChEBI] synonym: "thymus nucleic acid" RELATED [ChEBI] xref: CAS:9007-49-2 {source="ChemIDplus"} xref: CAS:9007-49-2 {source="KEGG COMPOUND"} xref: KEGG:C00039 is_a: CHEBI:33696 ! nucleic acid relationship: has_part CHEBI:33793 ! canonical deoxyribonucleoside residue relationship: has_part CHEBI:50298 ! canonical deoxyribonucleotide residue relationship: has_role CHEBI:75771 ! mouse metabolite relationship: has_role CHEBI:77746 ! human metabolite [Term] id: CHEBI:17029 name: chitin namespace: chebi_ontology alt_id: CHEBI:13962 alt_id: CHEBI:23099 alt_id: CHEBI:3596 def: "An aminoglycan consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues." [] subset: 3_STAR synonym: "(1->4)-2-acetamido-2-deoxy-beta-D-glucan" EXACT IUPAC_NAME [IUPAC] synonym: "[1,4-(N-Acetyl-beta-D-glucosaminyl)]n" RELATED [KEGG_COMPOUND] synonym: "[4)-beta-D-GlcpNAc(1->]n" RELATED [IUPAC] synonym: "beta-1,4-Poly-N-acetyl-D-glucosamine" RELATED [KEGG_COMPOUND] synonym: "Chitin" EXACT [KEGG_COMPOUND] synonym: "chitin" EXACT [IUPAC] synonym: "chitin" EXACT [UniProt] xref: CAS:1398-61-4 {source="KEGG COMPOUND"} xref: KEGG:C00461 xref: KEGG:G10483 is_a: CHEBI:21638 ! N-acylglucosamine is_a: CHEBI:22506 ! aminoglycan relationship: has_role CHEBI:73336 ! vulnerary relationship: has_role CHEBI:75771 ! mouse metabolite relationship: has_role CHEBI:75772 ! Saccharomyces cerevisiae metabolite relationship: has_role CHEBI:77746 ! human metabolite property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "H2O(C8H13NO5)n" xsd:string [Term] id: CHEBI:17087 name: ketone namespace: chebi_ontology alt_id: CHEBI:13427 alt_id: CHEBI:13646 alt_id: CHEBI:24974 alt_id: CHEBI:6127 alt_id: CHEBI:8742 def: "A compound in which a carbonyl group is bonded to two carbon atoms: R2C=O (neither R may be H)." [] subset: 3_STAR synonym: "a ketone" RELATED [UniProt] synonym: "cetone" RELATED [ChEBI] synonym: "Keton" RELATED [ChEBI] synonym: "Ketone" EXACT [KEGG_COMPOUND] synonym: "ketones" EXACT IUPAC_NAME [IUPAC] synonym: "ketones" RELATED [ChEBI] synonym: "R-CO-R'" RELATED [KEGG_COMPOUND] xref: KEGG:C01450 xref: Wikipedia:Ketone is_a: CHEBI:36586 ! carbonyl compound property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "COR2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "28.010" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "27.99491" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[*]C([*])=O" xsd:string [Term] id: CHEBI:17089 name: glycoprotein namespace: chebi_ontology alt_id: CHEBI:14349 alt_id: CHEBI:5481 alt_id: CHEBI:5493 def: "A compound in which a carbohydrate component is covalently bound to a protein component." [] subset: 3_STAR synonym: "a glycoprotein" RELATED [UniProt] synonym: "glicoproteina" RELATED [ChEBI] synonym: "glicoproteinas" RELATED [ChEBI] synonym: "Glycoprotein" EXACT [KEGG_COMPOUND] synonym: "glycoproteine" RELATED [ChEBI] synonym: "glycoproteines" RELATED [ChEBI] synonym: "glycoproteins" EXACT IUPAC_NAME [IUPAC] synonym: "Glykoprotein" RELATED [ChEBI] synonym: "Glykoproteine" RELATED [ChEBI] xref: KEGG:C00326 is_a: CHEBI:33837 ! conjugated protein is_a: CHEBI:63299 ! carbohydrate derivative [Term] id: CHEBI:17234 name: glucose namespace: chebi_ontology alt_id: CHEBI:14313 alt_id: CHEBI:24277 alt_id: CHEBI:33929 alt_id: CHEBI:5418 def: "An aldohexose used as a source of energy and metabolic intermediate." [] subset: 3_STAR synonym: "DL-glucose" RELATED [ChEBI] synonym: "Glc" RELATED [JCBN] synonym: "gluco-hexose" EXACT IUPAC_NAME [IUPAC] synonym: "Glucose" EXACT [KEGG_COMPOUND] synonym: "glucose" EXACT IUPAC_NAME [IUPAC] synonym: "Glukose" RELATED [ChEBI] xref: CAS:50-99-7 {source="KEGG COMPOUND"} xref: KEGG:C00293 xref: Wikipedia:Glucose is_a: CHEBI:33917 ! aldohexose relationship: has_role CHEBI:78675 ! fundamental metabolite property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C6H12O6" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "180.15588" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "180.06339" xsd:string [Term] id: CHEBI:17544 name: hydrogencarbonate namespace: chebi_ontology alt_id: CHEBI:13363 alt_id: CHEBI:22863 alt_id: CHEBI:40961 alt_id: CHEBI:5589 def: "The carbon oxoanion resulting from the removal of a proton from carbonic acid." [] subset: 3_STAR synonym: "[CO2(OH)](-)" RELATED [IUPAC] synonym: "Acid carbonate" RELATED [KEGG_COMPOUND] synonym: "Bicarbonate" RELATED [KEGG_COMPOUND] synonym: "BICARBONATE ION" RELATED [PDBeChem] synonym: "HCO3(-)" RELATED [IUPAC] synonym: "HCO3-" RELATED [KEGG_COMPOUND] synonym: "hydrogen carbonate" RELATED [PDBeChem] synonym: "hydrogen(trioxidocarbonate)(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "Hydrogencarbonate" EXACT [KEGG_COMPOUND] synonym: "hydrogencarbonate" EXACT [UniProt] synonym: "hydrogencarbonate" EXACT IUPAC_NAME [IUPAC] synonym: "hydrogencarbonate(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "hydrogentrioxocarbonate(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "hydrogentrioxocarbonate(IV)" EXACT IUPAC_NAME [IUPAC] synonym: "hydroxidodioxidocarbonate(1-)" EXACT IUPAC_NAME [IUPAC] xref: Beilstein:3903504 {source="Beilstein"} xref: CAS:71-52-3 {source="ChemIDplus"} xref: Gmelin:49249 {source="Gmelin"} xref: HMDB:HMDB0000595 xref: KEGG:C00288 xref: MetaCyc:HCO3 xref: PDBeChem:BCT xref: PMID:17215880 {source="Europe PMC"} xref: PMID:17505962 {source="Europe PMC"} xref: PMID:18439416 {source="Europe PMC"} xref: PMID:28732801 {source="Europe PMC"} xref: PMID:29150416 {source="Europe PMC"} xref: PMID:29460248 {source="Europe PMC"} xref: PMID:29466234 {source="Europe PMC"} xref: PMID:4208463 {source="Europe PMC"} xref: Wikipedia:Bicarbonate is_a: CHEBI:35604 ! carbon oxoanion relationship: has_role CHEBI:23357 ! cofactor relationship: has_role CHEBI:75771 ! mouse metabolite relationship: has_role CHEBI:75772 ! Saccharomyces cerevisiae metabolite relationship: has_role CHEBI:76971 ! Escherichia coli metabolite relationship: has_role CHEBI:77746 ! human metabolite relationship: is_conjugate_acid_of CHEBI:41609 ! carbonate relationship: is_conjugate_base_of CHEBI:28976 ! carbonic acid property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CHO3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "BVKZGUZCCUSVTD-UHFFFAOYSA-M" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "61.01684" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "60.99312" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "OC([O-])=O" xsd:string [Term] id: CHEBI:17891 name: donor namespace: chebi_ontology alt_id: CHEBI:14202 alt_id: CHEBI:4697 def: "A molecular entity that can transfer (\"donate\") an electron, a pair of electrons, an atom or a group to another molecular entity." [] subset: 3_STAR synonym: "Donator" RELATED [ChEBI] synonym: "donneur" RELATED [ChEBI] synonym: "Donor" EXACT [KEGG_COMPOUND] xref: KEGG:C01351 is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:18059 name: lipid namespace: chebi_ontology alt_id: CHEBI:14517 alt_id: CHEBI:25054 alt_id: CHEBI:6486 def: "'Lipids' is a loosely defined term for substances of biological origin that are soluble in nonpolar solvents. They consist of saponifiable lipids, such as glycerides (fats and oils) and phospholipids, as well as nonsaponifiable lipids, principally steroids." [] subset: 3_STAR synonym: "Lipid" EXACT [KEGG_COMPOUND] synonym: "lipids" EXACT IUPAC_NAME [IUPAC] xref: KEGG:C01356 is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:18085 name: glycosaminoglycan namespace: chebi_ontology alt_id: CHEBI:14361 alt_id: CHEBI:24398 alt_id: CHEBI:5495 def: "Any polysaccharide containing a substantial proportion of aminomonosaccharide residues." [] subset: 3_STAR synonym: "glicosaminoglicano" RELATED [IUPAC] synonym: "Glycosaminoglycan" EXACT [KEGG_COMPOUND] synonym: "glycosaminoglycan" EXACT IUPAC_NAME [IUPAC] synonym: "glycosaminoglycane" RELATED [IUPAC] synonym: "glycosaminoglycans" RELATED [ChEBI] synonym: "Glykosaminoglykan" RELATED [ChEBI] xref: KEGG:C02545 xref: Wikipedia:Glycosaminoglycan is_a: CHEBI:22506 ! aminoglycan [Term] id: CHEBI:18133 name: hexose namespace: chebi_ontology alt_id: CHEBI:14399 alt_id: CHEBI:24590 alt_id: CHEBI:5709 def: "Any six-carbon monosaccharide which in its linear form contains either an aldehyde group at position 1 (aldohexose) or a ketone group at position 2 (ketohexose)." [] subset: 3_STAR synonym: "Hexose" EXACT [KEGG_COMPOUND] synonym: "hexoses" RELATED [ChEBI] synonym: "WURCS=2.0/1,1,0/[axxxxh-1x_1-5_2*NCC/3=O]/1/" RELATED [GlyTouCan] xref: GlyGen:G70994MS xref: GlyTouCan:G70994MS xref: KEGG:C00738 is_a: CHEBI:35381 ! monosaccharide [Term] id: CHEBI:18154 name: polysaccharide namespace: chebi_ontology alt_id: CHEBI:14864 alt_id: CHEBI:26205 alt_id: CHEBI:8322 def: "A biomacromolecule consisting of large numbers of monosaccharide residues linked glycosidically. This term is commonly used only for those containing more than ten monosaccharide residues." [] subset: 3_STAR synonym: "Glycan" RELATED [KEGG_COMPOUND] synonym: "Glycane" RELATED [ChEBI] synonym: "glycans" RELATED [IUPAC] synonym: "Glykan" RELATED [ChEBI] synonym: "Glykane" RELATED [ChEBI] synonym: "polisacarido" RELATED [ChEBI] synonym: "polisacaridos" RELATED [IUPAC] synonym: "Polysaccharide" EXACT [KEGG_COMPOUND] synonym: "polysaccharides" EXACT IUPAC_NAME [IUPAC] xref: KEGG:C00420 is_a: CHEBI:16646 ! carbohydrate is_a: CHEBI:167559 ! glycan is_a: CHEBI:33694 ! biomacromolecule [Term] id: CHEBI:18282 name: nucleobase namespace: chebi_ontology alt_id: CHEBI:13873 alt_id: CHEBI:25598 alt_id: CHEBI:2995 def: "That part of DNA or RNA that may be involved in pairing." [] subset: 3_STAR synonym: "Base" RELATED [KEGG_COMPOUND] synonym: "nucleobases" RELATED [ChEBI] xref: KEGG:C00701 xref: Wikipedia:Nucleobase is_a: CHEBI:38101 ! organonitrogen heterocyclic compound [Term] id: CHEBI:18357 name: (R)-noradrenaline namespace: chebi_ontology alt_id: CHEBI:1 alt_id: CHEBI:14668 alt_id: CHEBI:25592 alt_id: CHEBI:258884 alt_id: CHEBI:43725 def: "The R-enantiomer of noradrenaline." [] subset: 3_STAR synonym: "(-)-arterenol" RELATED [ChemIDplus] synonym: "(-)-noradrenaline" RELATED [IUPHAR] synonym: "(-)-norepinephrine" RELATED [ChemIDplus] synonym: "(R)-(-)-norepinephrine" RELATED [ChemIDplus] synonym: "(R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol" RELATED [ChemIDplus] synonym: "(R)-norepinephrine" RELATED [ChemIDplus] synonym: "4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol" RELATED [KEGG_COMPOUND] synonym: "4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol" EXACT IUPAC_NAME [IUPAC] synonym: "Arterenol" RELATED [KEGG_COMPOUND] synonym: "L-Noradrenaline" RELATED [KEGG_COMPOUND] synonym: "L-NOREPINEPHRINE" RELATED [PDBeChem] synonym: "Noradrenaline" RELATED [KEGG_COMPOUND] synonym: "norepinefrina" RELATED INN [ChEBI] synonym: "Norepinephrine" RELATED [KEGG_COMPOUND] synonym: "norepinephrine" RELATED INN [ChemIDplus] synonym: "norepinephrine" RELATED INN [WHO_MedNet] synonym: "norepinephrinum" RELATED INN [ChEBI] xref: Beilstein:2804840 {source="Beilstein"} xref: Beilstein:4231961 {source="ChemIDplus"} xref: CAS:51-41-2 {source="ChemIDplus"} xref: CAS:51-41-2 {source="KEGG COMPOUND"} xref: Drug_Central:1960 {source="DrugCentral"} xref: DrugBank:DB00368 xref: HMDB:HMDB0000216 xref: KEGG:C00547 xref: KEGG:D00076 xref: KNApSAcK:C00001424 xref: PDBeChem:LNR xref: Reaxys:2804840 {source="Reaxys"} xref: Wikipedia:Norepinephrine is_a: CHEBI:33569 ! noradrenaline relationship: has_role CHEBI:25512 ! neurotransmitter relationship: has_role CHEBI:35524 ! sympathomimetic agent relationship: has_role CHEBI:35569 ! alpha-adrenergic agonist relationship: has_role CHEBI:50514 ! vasoconstrictor agent relationship: has_role CHEBI:75771 ! mouse metabolite relationship: is_conjugate_base_of CHEBI:72587 ! (R)-noradrenaline(1+) relationship: is_enantiomer_of CHEBI:33571 ! (S)-noradrenaline property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C8H11NO3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m0/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "SFLSHLFXELFNJZ-QMMMGPOBSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "169.17780" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "169.07389" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "NC[C@H](O)c1ccc(O)c(O)c1" xsd:string [Term] id: CHEBI:18367 name: phosphate(3-) namespace: chebi_ontology alt_id: CHEBI:14791 alt_id: CHEBI:45024 alt_id: CHEBI:7793 def: "A phosphate ion that is the conjugate base of hydrogenphosphate." [] subset: 3_STAR synonym: "[PO4](3-)" RELATED [IUPAC] synonym: "Orthophosphate" RELATED [KEGG_COMPOUND] synonym: "Phosphate" RELATED [KEGG_COMPOUND] synonym: "phosphate" EXACT IUPAC_NAME [IUPAC] synonym: "PHOSPHATE ION" RELATED [PDBeChem] synonym: "PO4(3-)" RELATED [IUPAC] synonym: "tetraoxidophosphate(3-)" EXACT IUPAC_NAME [IUPAC] synonym: "tetraoxophosphate(3-)" EXACT IUPAC_NAME [IUPAC] synonym: "tetraoxophosphate(V)" EXACT IUPAC_NAME [IUPAC] xref: Beilstein:3903772 {source="Beilstein"} xref: CAS:14265-44-2 {source="KEGG COMPOUND"} xref: CAS:14265-44-2 {source="ChemIDplus"} xref: Gmelin:1997 {source="Gmelin"} xref: KEGG:C00009 xref: PDBeChem:PO4 {source="ChEBI"} xref: Reaxys:3903772 {source="Reaxys"} is_a: CHEBI:35780 ! phosphate ion is_a: CHEBI:79387 ! trivalent inorganic anion relationship: is_conjugate_base_of CHEBI:43474 ! hydrogenphosphate property_value: http://purl.obolibrary.org/obo/chebi/charge "-3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "O4P" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "NBIIXXVUZAFLBC-UHFFFAOYSA-K" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "94.97136" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "94.95507" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]P([O-])([O-])=O" xsd:string [Term] id: CHEBI:20664 name: 5beta-cholane namespace: chebi_ontology subset: 3_STAR synonym: "5beta-cholane" EXACT IUPAC_NAME [IUPAC] xref: Beilstein:2048472 {source="Beilstein"} is_a: CHEBI:35519 ! cholane property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C24H42" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C24H42/c1-5-8-17(2)20-12-13-21-19-11-10-18-9-6-7-15-23(18,3)22(19)14-16-24(20,21)4/h17-22H,5-16H2,1-4H3/t17-,18+,19+,20-,21+,22+,23+,24-/m1/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QSHQKIURKJITMZ-OBUPQJQESA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "330.59028" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "330.32865" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][C@@]12CCCC[C@]1(C)[C@@]1([H])CC[C@]3(C)[C@]([H])(CC[C@@]3([H])[C@]1([H])CC2)[C@H](C)CCC" xsd:string [Term] id: CHEBI:21638 name: N-acylglucosamine namespace: chebi_ontology subset: 3_STAR synonym: "N-acylglucosamine" EXACT [ChEBI] synonym: "N-acylglucosamines" RELATED [ChEBI] is_a: CHEBI:21656 ! N-acyl-hexosamine is_a: CHEBI:24271 ! glucosamines [Term] id: CHEBI:21656 name: N-acyl-hexosamine namespace: chebi_ontology subset: 3_STAR synonym: "N-acyl-hexosamine" EXACT [ChEBI] synonym: "N-acyl-hexosamines" RELATED [ChEBI] is_a: CHEBI:24586 ! hexosamine [Term] id: CHEBI:22221 name: acyl group namespace: chebi_ontology def: "An organic group formed by removing one or more hydroxy groups from an oxoacid that has the general structure RkE(=O)l(OH)m (l =/= 0). Although the term is almost always applied to organic compounds, with carboxylic acid as the oxoacid, acyl groups can in principle be derived from other types of acids such as sulfonic acids or phosphonic acids." [] subset: 3_STAR synonym: "acyl group" EXACT [IUPAC] synonym: "acyl groups" RELATED [ChEBI] synonym: "alkanoyl" EXACT IUPAC_NAME [IUPAC] synonym: "alkanoyl group" RELATED [ChEBI] synonym: "groupe acyle" RELATED [IUPAC] is_a: CHEBI:33247 ! organic group [Term] id: CHEBI:22314 name: alkali metal atom namespace: chebi_ontology subset: 3_STAR synonym: "alkali metal" RELATED [ChEBI] synonym: "alkali metals" EXACT IUPAC_NAME [IUPAC] synonym: "Alkalimetall" RELATED [ChEBI] synonym: "Alkalimetalle" RELATED [ChEBI] synonym: "metal alcalin" RELATED [ChEBI] synonym: "metal alcalino" RELATED [ChEBI] synonym: "metales alcalinos" RELATED [ChEBI] synonym: "metaux alcalins" RELATED [ChEBI] is_a: CHEBI:33318 ! main group element atom is_a: CHEBI:33521 ! metal atom is_a: CHEBI:33559 ! s-block element atom [Term] id: CHEBI:22315 name: alkaloid namespace: chebi_ontology def: "Any of the naturally occurring, basic nitrogen compounds (mostly heterocyclic) occurring mostly in the plant kingdom, but also found in bacteria, fungi, and animals. By extension, certain neutral compounds biogenetically related to basic alkaloids are also classed as alkaloids. Amino acids, peptides, proteins, nucleotides, nucleic acids, amino sugars and antibiotics are not normally regarded as alkaloids. Compounds in which the nitrogen is exocyclic (dopamine, mescaline, serotonin, etc.) are usually classed as amines rather than alkaloids." [] subset: 3_STAR synonym: "alcaloide" RELATED [ChEBI] synonym: "alcaloides" RELATED [ChEBI] synonym: "Alkaloid" EXACT [ChEBI] synonym: "Alkaloide" RELATED [ChEBI] synonym: "alkaloids" EXACT IUPAC_NAME [IUPAC] xref: Wikipedia:Alkaloid is_a: CHEBI:35352 ! organonitrogen compound relationship: has_role CHEBI:25212 ! metabolite [Term] id: CHEBI:22506 name: aminoglycan namespace: chebi_ontology subset: 3_STAR synonym: "aminoglycans" RELATED [ChEBI] is_a: CHEBI:35352 ! organonitrogen compound is_a: CHEBI:65212 ! polysaccharide derivative [Term] id: CHEBI:22563 name: anion namespace: chebi_ontology def: "A monoatomic or polyatomic species having one or more elementary charges of the electron." [] subset: 3_STAR synonym: "Anion" EXACT [ChEBI] synonym: "anion" EXACT IUPAC_NAME [IUPAC] synonym: "anion" EXACT [ChEBI] synonym: "Anionen" RELATED [ChEBI] synonym: "aniones" RELATED [ChEBI] synonym: "anions" RELATED [IUPAC] is_a: CHEBI:24870 ! ion [Term] id: CHEBI:22586 name: antioxidant namespace: chebi_ontology def: "A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides." [] subset: 3_STAR synonym: "antioxidants" RELATED [ChEBI] synonym: "antioxydant" RELATED [ChEBI] synonym: "antoxidant" RELATED [ChEBI] is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:22695 name: base namespace: chebi_ontology def: "A molecular entity having an available pair of electrons capable of forming a covalent bond with a hydron (Bronsted base) or with the vacant orbital of some other molecular entity (Lewis base)." [] subset: 3_STAR synonym: "Base" EXACT [ChEBI] synonym: "base" EXACT [ChEBI] synonym: "base" EXACT IUPAC_NAME [IUPAC] synonym: "Base1" RELATED [KEGG_COMPOUND] synonym: "Base2" RELATED [KEGG_COMPOUND] synonym: "Basen" RELATED [ChEBI] synonym: "bases" RELATED [ChEBI] synonym: "Nucleobase" RELATED [KEGG_COMPOUND] xref: KEGG:C00701 is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:22728 name: benzopyrrole namespace: chebi_ontology subset: 3_STAR synonym: "benzopyrroles" RELATED [ChEBI] is_a: CHEBI:27171 ! organic heterobicyclic compound is_a: CHEBI:38101 ! organonitrogen heterocyclic compound is_a: CHEBI:38180 ! polycyclic heteroarene [Term] id: CHEBI:22868 name: bile salt namespace: chebi_ontology def: "A sodium salt of the conjugate of any bile acid with either glycine or taurine." [] subset: 3_STAR synonym: "Bile acid" RELATED [KEGG_COMPOUND] synonym: "bile salts" RELATED [ChEBI] xref: KEGG:C01558 is_a: CHEBI:36078 ! cholanoid is_a: CHEBI:38700 ! organic sodium salt [Term] id: CHEBI:23004 name: carbamoyl group namespace: chebi_ontology def: "The univalent carboacyl group formed by loss of -OH from the carboxy group of carbamic acid." [] subset: 3_STAR synonym: "-C(O)NH2" RELATED [ChEBI] synonym: "-CONH2" RELATED [IUPAC] synonym: "aminocarbonyl" RELATED [IUPAC] synonym: "carbamoyl" EXACT IUPAC_NAME [IUPAC] synonym: "carbamyl" RELATED [ChEBI] synonym: "carbamyl group" RELATED [ChEBI] synonym: "carboxamide" RELATED [IUPAC] xref: PMID:24168430 {source="Europe PMC"} is_a: CHEBI:27207 ! univalent carboacyl group relationship: is_substituent_group_from CHEBI:28616 ! carbamic acid property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CH2NO" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "44.03272" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "44.01364" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "*C(N)=O" xsd:string [Term] id: CHEBI:23019 name: carbonyl group namespace: chebi_ontology subset: 3_STAR synonym: ">C=O" RELATED [IUPAC] synonym: "carbonyl" EXACT IUPAC_NAME [IUPAC] synonym: "carbonyl group" EXACT [ChEBI] synonym: "carbonyl group" EXACT [UniProt] is_a: CHEBI:51422 ! organodiyl group property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CO" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "28.01010" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "27.99491" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "O=C(*)*" xsd:string [Term] id: CHEBI:23357 name: cofactor namespace: chebi_ontology def: "An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group)." [] subset: 3_STAR synonym: "cofactor" EXACT [IUPAC] synonym: "cofactors" EXACT IUPAC_NAME [IUPAC] xref: Wikipedia:Cofactor_(biochemistry) is_a: CHEBI:52206 ! biochemical role [Term] id: CHEBI:23367 name: molecular entity namespace: chebi_ontology def: "Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity." [fake:2] subset: 3_STAR synonym: "entidad molecular" RELATED [IUPAC] synonym: "entidades moleculares" RELATED [IUPAC] synonym: "entite moleculaire" RELATED [IUPAC] synonym: "molecular entities" RELATED [IUPAC] synonym: "molecular entity" EXACT IUPAC_NAME [IUPAC] synonym: "molekulare Entitaet" RELATED [ChEBI] is_a: CHEBI:24431 ! chemical entity [Term] id: CHEBI:23449 name: cyclic peptide namespace: chebi_ontology subset: 3_STAR synonym: "cyclic peptides" RELATED [ChEBI] synonym: "Cyclopeptid" RELATED [ChEBI] synonym: "peptide cyclique" RELATED [IUPAC] synonym: "peptido ciclico" RELATED [IUPAC] synonym: "Zyklopeptid" RELATED [ChEBI] is_a: CHEBI:16670 ! peptide [Term] id: CHEBI:23888 name: drug namespace: chebi_ontology def: "Any substance which when absorbed into a living organism may modify one or more of its functions. The term is generally accepted for a substance taken for a therapeutic purpose, but is also commonly used for abused substances." [] subset: 3_STAR synonym: "drugs" RELATED [ChEBI] synonym: "medicine" RELATED [ChEBI] is_a: CHEBI:52217 ! pharmaceutical [Term] id: CHEBI:23906 name: monoatomic cation namespace: chebi_ontology subset: 3_STAR synonym: "monoatomic cations" RELATED [ChEBI] is_a: CHEBI:24867 ! monoatomic ion is_a: CHEBI:36916 ! cation [Term] id: CHEBI:23924 name: enzyme inhibitor namespace: chebi_ontology def: "A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction." [] subset: 3_STAR synonym: "enzyme inhibitor" EXACT IUPAC_NAME [IUPAC] synonym: "enzyme inhibitors" RELATED [ChEBI] synonym: "inhibidor enzimatico" RELATED [ChEBI] synonym: "inhibidores enzimaticos" RELATED [ChEBI] synonym: "inhibiteur enzymatique" RELATED [ChEBI] synonym: "inhibiteurs enzymatiques" RELATED [ChEBI] is_a: CHEBI:35222 ! inhibitor is_a: CHEBI:52206 ! biochemical role [Term] id: CHEBI:24271 name: glucosamines namespace: chebi_ontology def: "Any hexosamine that is glucose in which at least one of the hydroxy groups has been replaced by an amino group." [] subset: 3_STAR is_a: CHEBI:24586 ! hexosamine [Term] id: CHEBI:24384 name: glycogens namespace: chebi_ontology subset: 3_STAR is_a: CHEBI:37163 ! glucan [Term] id: CHEBI:24431 name: chemical entity namespace: chebi_ontology def: "A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances." [] subset: 3_STAR synonym: "chemical entity" EXACT [UniProt] is_a: BFO:0000030 ! object [Term] id: CHEBI:24432 name: biological role namespace: chebi_ontology def: "A role played by the molecular entity or part thereof within a biological context." [] subset: 3_STAR synonym: "biological function" RELATED [ChEBI] is_a: CHEBI:50906 ! role [Term] id: CHEBI:24433 name: group namespace: chebi_ontology def: "A defined linked collection of atoms or a single atom within a molecular entity." [] subset: 3_STAR synonym: "group" EXACT IUPAC_NAME [IUPAC] synonym: "groupe" RELATED [IUPAC] synonym: "grupo" RELATED [IUPAC] synonym: "grupos" RELATED [IUPAC] synonym: "Gruppe" RELATED [ChEBI] synonym: "Rest" RELATED [ChEBI] is_a: CHEBI:24431 ! chemical entity relationship: has_part CHEBI:33250 ! atom [Term] id: CHEBI:24532 name: organic heterocyclic compound namespace: chebi_ontology def: "A cyclic compound having as ring members atoms of carbon and at least of one other element." [] subset: 3_STAR synonym: "organic heterocycle" RELATED [ChEBI] synonym: "organic heterocyclic compounds" RELATED [ChEBI] is_a: CHEBI:33285 ! heteroorganic entity is_a: CHEBI:33832 ! organic cyclic compound is_a: CHEBI:5686 ! heterocyclic compound [Term] id: CHEBI:24533 name: heterodetic cyclic peptide namespace: chebi_ontology def: "A heterodetic cyclic peptide is a peptide consisting only of amino-acid residues, but in which the linkages forming the ring are not solely peptide bonds; one or more is an isopeptide, disulfide, ester, or other bond." [] subset: 3_STAR synonym: "heterodetic cyclic peptide" EXACT IUPAC_NAME [IUPAC] synonym: "heterodetic cyclic peptides" RELATED [ChEBI] synonym: "peptide cyclique heterodetique" RELATED [IUPAC] synonym: "peptido ciclico heterodetico" RELATED [IUPAC] is_a: CHEBI:23449 ! cyclic peptide [Term] id: CHEBI:24586 name: hexosamine namespace: chebi_ontology def: "Any 6-carbon amino monosaccharide with at least one alcoholic hydroxy group replaced by an amino group." [] subset: 3_STAR synonym: "hexosamine" EXACT [ChEBI] synonym: "hexosamines" RELATED [ChEBI] is_a: CHEBI:60926 ! amino monosaccharide [Term] id: CHEBI:24621 name: hormone namespace: chebi_ontology def: "Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds." [] subset: 3_STAR synonym: "endocrine" RELATED [ChEBI] synonym: "hormones" RELATED [ChEBI] is_a: CHEBI:33280 ! molecular messenger is_a: CHEBI:48705 ! agonist [Term] id: CHEBI:24651 name: hydroxides namespace: chebi_ontology def: "Hydroxides are chemical compounds containing a hydroxy group or salts containing hydroxide (OH(-))." [] subset: 3_STAR is_a: CHEBI:25806 ! oxygen molecular entity is_a: CHEBI:33608 ! hydrogen molecular entity is_a: CHEBI:37577 ! heteroatomic molecular entity relationship: has_part CHEBI:43176 ! hydroxy group [Term] id: CHEBI:24663 name: hydroxy-5beta-cholanic acid namespace: chebi_ontology def: "Any member of the class of 5beta-cholanic acids carrying at least one hydroxy group at unspecified position." [] subset: 3_STAR synonym: "hydroxy-5beta-cholanic acids" RELATED [ChEBI] is_a: CHEBI:33822 ! organic hydroxy compound is_a: CHEBI:36248 ! 5beta-cholanic acids relationship: has_functional_parent CHEBI:36238 ! 5beta-cholanic acid [Term] id: CHEBI:24828 name: indoles namespace: chebi_ontology def: "Any compound containing an indole skeleton." [] subset: 3_STAR is_a: CHEBI:22728 ! benzopyrrole [Term] id: CHEBI:24833 name: oxoacid namespace: chebi_ontology def: "A compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons)." [] subset: 3_STAR synonym: "oxacids" RELATED [ChEBI] synonym: "oxiacids" RELATED [ChEBI] synonym: "oxo acid" RELATED [ChEBI] synonym: "oxoacid" EXACT IUPAC_NAME [IUPAC] synonym: "oxoacids" EXACT IUPAC_NAME [IUPAC] synonym: "oxy-acids" RELATED [ChEBI] synonym: "oxyacids" RELATED [ChEBI] is_a: CHEBI:24651 ! hydroxides relationship: has_role CHEBI:39141 ! Bronsted acid [Term] id: CHEBI:24834 name: inorganic anion namespace: chebi_ontology subset: 3_STAR synonym: "inorganic anions" RELATED [ChEBI] is_a: CHEBI:22563 ! anion is_a: CHEBI:36914 ! inorganic ion [Term] id: CHEBI:24835 name: inorganic molecular entity namespace: chebi_ontology def: "A molecular entity that contains no carbon." [] subset: 3_STAR synonym: "anorganische Verbindungen" RELATED [ChEBI] synonym: "inorganic compounds" RELATED [ChEBI] synonym: "inorganic entity" RELATED [ChEBI] synonym: "inorganic molecular entities" RELATED [ChEBI] synonym: "inorganics" RELATED [ChEBI] is_a: CHEBI:23367 ! molecular entity [Term] id: CHEBI:24836 name: inorganic oxide namespace: chebi_ontology subset: 3_STAR synonym: "inorganic oxides" RELATED [ChEBI] is_a: CHEBI:24835 ! inorganic molecular entity is_a: CHEBI:25741 ! oxide [Term] id: CHEBI:24866 name: salt namespace: chebi_ontology def: "A salt is an assembly of cations and anions." [] subset: 3_STAR synonym: "ionic compound" RELATED [ChEBI] synonym: "ionic compounds" RELATED [ChEBI] synonym: "sal" RELATED [ChEBI] synonym: "sales" RELATED [ChEBI] synonym: "salt" EXACT IUPAC_NAME [IUPAC] synonym: "salts" RELATED [ChEBI] synonym: "Salz" RELATED [ChEBI] synonym: "Salze" RELATED [ChEBI] synonym: "sel" RELATED [ChEBI] synonym: "sels" RELATED [ChEBI] is_a: CHEBI:37577 ! heteroatomic molecular entity relationship: has_part CHEBI:22563 ! anion relationship: has_part CHEBI:36916 ! cation [Term] id: CHEBI:24867 name: monoatomic ion namespace: chebi_ontology subset: 3_STAR synonym: "monoatomic ions" RELATED [ChEBI] is_a: CHEBI:24870 ! ion is_a: CHEBI:33238 ! monoatomic entity [Term] id: CHEBI:24868 name: organic salt namespace: chebi_ontology subset: 3_STAR synonym: "organic salts" RELATED [ChEBI] synonym: "organisches Salz" RELATED [ChEBI] is_a: CHEBI:24866 ! salt [Term] id: CHEBI:24870 name: ion namespace: chebi_ontology def: "A molecular entity having a net electric charge." [] subset: 3_STAR synonym: "Ion" EXACT [ChEBI] synonym: "ion" EXACT IUPAC_NAME [IUPAC] synonym: "ion" EXACT [ChEBI] synonym: "Ionen" RELATED [ChEBI] synonym: "iones" RELATED [ChEBI] synonym: "ions" RELATED [ChEBI] is_a: CHEBI:23367 ! molecular entity [Term] id: CHEBI:25046 name: linear tetrapyrrole namespace: chebi_ontology subset: 1_STAR is_a: CHEBI:26932 ! tetrapyrrole [Term] id: CHEBI:25212 name: metabolite namespace: chebi_ontology alt_id: CHEBI:26619 alt_id: CHEBI:35220 def: "Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites." [] subset: 3_STAR synonym: "metabolite" EXACT IUPAC_NAME [IUPAC] synonym: "metabolites" RELATED [ChEBI] synonym: "primary metabolites" RELATED [ChEBI] synonym: "secondary metabolites" RELATED [ChEBI] is_a: CHEBI:52206 ! biochemical role [Term] id: CHEBI:25213 name: metal cation namespace: chebi_ontology subset: 3_STAR synonym: "a metal cation" RELATED [UniProt] synonym: "metal cations" RELATED [ChEBI] is_a: CHEBI:23906 ! monoatomic cation is_a: CHEBI:36915 ! inorganic cation [Term] id: CHEBI:25362 name: elemental molecule namespace: chebi_ontology def: "A molecule all atoms of which have the same atomic number." [] subset: 3_STAR synonym: "homoatomic molecule" RELATED [ChEBI] synonym: "homoatomic molecules" RELATED [ChEBI] is_a: CHEBI:25367 ! molecule is_a: CHEBI:33259 ! elemental molecular entity [Term] id: CHEBI:25367 name: molecule namespace: chebi_ontology def: "Any polyatomic entity that is an electrically neutral entity consisting of more than one atom." [] subset: 3_STAR synonym: "molecula" RELATED [IUPAC] synonym: "molecule" EXACT [IUPAC] synonym: "molecules" RELATED [IUPAC] synonym: "Molekuel" RELATED [ChEBI] synonym: "neutral molecular compounds" RELATED [IUPAC] is_a: CHEBI:36357 ! polyatomic entity [Term] id: CHEBI:25375 name: monoamine molecular messenger namespace: chebi_ontology def: "A group of neurotransmitters and neuromodulators that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan." [] subset: 3_STAR synonym: "monamines" RELATED [ChEBI] synonym: "monoamines" RELATED [ChEBI] is_a: CHEBI:63534 ! monoamine relationship: has_role CHEBI:33280 ! molecular messenger [Term] id: CHEBI:25384 name: monocarboxylic acid namespace: chebi_ontology def: "An oxoacid containing a single carboxy group." [] subset: 3_STAR synonym: "monocarboxylic acids" RELATED [ChEBI] is_a: CHEBI:33575 ! carboxylic acid relationship: is_conjugate_acid_of CHEBI:35757 ! monocarboxylic acid anion [Term] id: CHEBI:25414 name: monoatomic monocation namespace: chebi_ontology subset: 3_STAR synonym: "monoatomic monocations" RELATED [ChEBI] synonym: "monovalent inorganic cations" RELATED [ChEBI] is_a: CHEBI:23906 ! monoatomic cation property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "0.00000" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[*+]" xsd:string [Term] id: CHEBI:25512 name: neurotransmitter namespace: chebi_ontology def: "An endogenous compound that is used to transmit information across the synapse between a neuron and another cell." [] subset: 3_STAR synonym: "neurotransmitters" RELATED [ChEBI] xref: Wikipedia:Neurotransmitter is_a: CHEBI:33280 ! molecular messenger [Term] id: CHEBI:25555 name: nitrogen atom namespace: chebi_ontology subset: 3_STAR synonym: "7N" RELATED [IUPAC] synonym: "azote" RELATED [IUPAC] synonym: "N" RELATED [IUPAC] synonym: "nitrogen" EXACT IUPAC_NAME [IUPAC] synonym: "nitrogen" RELATED [ChEBI] synonym: "nitrogeno" RELATED [ChEBI] synonym: "Stickstoff" RELATED [ChEBI] xref: WebElements:N is_a: CHEBI:25585 ! nonmetal atom is_a: CHEBI:33300 ! pnictogen relationship: has_role CHEBI:33937 ! macronutrient property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "14.007" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "14.00307" xsd:string [Term] id: CHEBI:25585 name: nonmetal atom namespace: chebi_ontology subset: 3_STAR synonym: "Nichtmetall" RELATED [ChEBI] synonym: "Nichtmetalle" RELATED [ChEBI] synonym: "no metal" RELATED [ChEBI] synonym: "no metales" RELATED [ChEBI] synonym: "non-metal" RELATED [ChEBI] synonym: "non-metaux" RELATED [ChEBI] synonym: "nonmetal" EXACT IUPAC_NAME [IUPAC] synonym: "nonmetal" RELATED [ChEBI] synonym: "nonmetals" RELATED [ChEBI] is_a: CHEBI:33250 ! atom [Term] id: CHEBI:25696 name: organic anion namespace: chebi_ontology def: "Any organic ion with a net negative charge." [] subset: 3_STAR synonym: "organic anions" RELATED [ChEBI] is_a: CHEBI:22563 ! anion is_a: CHEBI:25699 ! organic ion [Term] id: CHEBI:25697 name: organic cation namespace: chebi_ontology def: "Any organic ion with a net positive charge." [] subset: 3_STAR synonym: "organic cations" RELATED [ChEBI] is_a: CHEBI:25699 ! organic ion is_a: CHEBI:36916 ! cation [Term] id: CHEBI:25699 name: organic ion namespace: chebi_ontology subset: 3_STAR synonym: "organic ions" RELATED [ChEBI] is_a: CHEBI:24870 ! ion is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:25704 name: organic sulfate namespace: chebi_ontology def: "Compounds of the general formula SO3HOR where R is an organyl group" [] subset: 3_STAR synonym: "organic sulfates" RELATED [ChEBI] is_a: CHEBI:26820 ! sulfates relationship: is_conjugate_acid_of CHEBI:58958 ! organosulfate oxoanion [Term] id: CHEBI:25741 name: oxide namespace: chebi_ontology def: "An oxide is a chemical compound of oxygen with other chemical elements." [] subset: 3_STAR synonym: "oxide" EXACT [ChEBI] synonym: "oxides" RELATED [ChEBI] is_a: CHEBI:25806 ! oxygen molecular entity is_a: CHEBI:37577 ! heteroatomic molecular entity [Term] id: CHEBI:25805 name: oxygen atom namespace: chebi_ontology subset: 3_STAR synonym: "8O" RELATED [IUPAC] synonym: "O" RELATED [IUPAC] synonym: "oxigeno" RELATED [ChEBI] synonym: "oxygen" EXACT IUPAC_NAME [IUPAC] synonym: "oxygen" RELATED [ChEBI] synonym: "oxygene" RELATED [ChEBI] synonym: "Sauerstoff" RELATED [ChEBI] xref: KEGG:C00007 xref: WebElements:O is_a: CHEBI:25585 ! nonmetal atom is_a: CHEBI:33303 ! chalcogen relationship: has_role CHEBI:33937 ! macronutrient property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QVGXLLKOCUKJST-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "15.99940" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "15.99491" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O]" xsd:string [Term] id: CHEBI:25806 name: oxygen molecular entity namespace: chebi_ontology subset: 3_STAR synonym: "oxygen molecular entities" RELATED [ChEBI] synonym: "oxygen molecular entity" EXACT [ChEBI] is_a: CHEBI:33304 ! chalcogen molecular entity relationship: has_part CHEBI:25805 ! oxygen atom [Term] id: CHEBI:25905 name: peptide hormone namespace: chebi_ontology def: "Any peptide with hormonal activity in animals, whether endocrine, neuroendocrine, or paracrine." [] subset: 3_STAR synonym: "peptide hormones" RELATED [ChEBI] synonym: "polypeptide hormone" RELATED [ChEBI] is_a: CHEBI:16670 ! peptide relationship: has_role CHEBI:24621 ! hormone [Term] id: CHEBI:26020 name: phosphate namespace: chebi_ontology def: "Salts and esters of phosphoric and oligophosphoric acids and their chalcogen analogues. In inorganic chemistry, the term is also used to describe anionic coordination entities with phosphorus as central atom." [] subset: 3_STAR synonym: "phosphates" EXACT IUPAC_NAME [IUPAC] synonym: "phosphates" RELATED [ChEBI] is_a: CHEBI:26079 ! phosphoric acid derivative [Term] id: CHEBI:26078 name: phosphoric acid namespace: chebi_ontology def: "A phosphorus oxoacid that consists of one oxo and three hydroxy groups joined covalently to a central phosphorus atom." [] subset: 3_STAR synonym: "[PO(OH)3]" RELATED [IUPAC] synonym: "acide phosphorique" RELATED [ChEBI] synonym: "acidum phosphoricum" RELATED [ChEBI] synonym: "H3PO4" RELATED [IUPAC] synonym: "Orthophosphoric acid" RELATED [KEGG_COMPOUND] synonym: "orthophosphoric acid" RELATED [NIST_Chemistry_WebBook] synonym: "Phosphate" RELATED [KEGG_COMPOUND] synonym: "Phosphoric acid" EXACT [KEGG_COMPOUND] synonym: "phosphoric acid" EXACT [IUPAC] synonym: "Phosphorsaeure" RELATED [ChEBI] synonym: "Phosphorsaeureloesungen" RELATED [ChEBI] synonym: "tetraoxophosphoric acid" EXACT IUPAC_NAME [IUPAC] synonym: "trihydrogen tetraoxophosphate(3-)" EXACT IUPAC_NAME [IUPAC] synonym: "trihydroxidooxidophosphorus" EXACT IUPAC_NAME [IUPAC] xref: Beilstein:1921286 {source="Beilstein"} xref: CAS:7664-38-2 {source="NIST Chemistry WebBook"} xref: CAS:7664-38-2 {source="KEGG COMPOUND"} xref: CAS:7664-38-2 {source="ChemIDplus"} xref: Drug_Central:4478 {source="DrugCentral"} xref: Gmelin:2000 {source="Gmelin"} xref: HMDB:HMDB0002142 xref: KEGG:C00009 xref: KEGG:D05467 xref: KNApSAcK:C00007408 xref: PMID:11455380 {source="Europe PMC"} xref: PMID:15630224 {source="Europe PMC"} xref: PMID:17439666 {source="Europe PMC"} xref: PMID:17518491 {source="Europe PMC"} xref: PMID:22282755 {source="Europe PMC"} xref: PMID:22333268 {source="Europe PMC"} xref: PMID:22381614 {source="Europe PMC"} xref: PMID:22401268 {source="Europe PMC"} xref: Reaxys:1921286 {source="Reaxys"} xref: Wikipedia:Phosphoric_Acid is_a: CHEBI:59698 ! phosphoric acids relationship: has_role CHEBI:33287 ! fertilizer relationship: has_role CHEBI:46787 ! solvent relationship: has_role CHEBI:77746 ! human metabolite relationship: has_role CHEBI:84735 ! algal metabolite relationship: is_conjugate_acid_of CHEBI:39745 ! dihydrogenphosphate property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "H3O4P" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "NBIIXXVUZAFLBC-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "97.99520" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "97.97690" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]OP(=O)(O[H])O[H]" xsd:string [Term] id: CHEBI:26079 name: phosphoric acid derivative namespace: chebi_ontology subset: 1_STAR is_a: CHEBI:36359 ! phosphorus oxoacid derivative relationship: has_functional_parent CHEBI:26078 ! phosphoric acid [Term] id: CHEBI:26082 name: phosphorus molecular entity namespace: chebi_ontology subset: 3_STAR synonym: "phosphorus molecular entities" RELATED [ChEBI] is_a: CHEBI:33302 ! pnictogen molecular entity relationship: has_part CHEBI:28659 ! phosphorus atom [Term] id: CHEBI:26708 name: sodium atom namespace: chebi_ontology subset: 3_STAR synonym: "11Na" RELATED [IUPAC] synonym: "Na" RELATED [IUPAC] synonym: "Natrium" RELATED [ChemIDplus] synonym: "natrium" RELATED [IUPAC] synonym: "sodio" RELATED [ChemIDplus] synonym: "sodium" EXACT IUPAC_NAME [IUPAC] synonym: "sodium" RELATED [ChEBI] xref: CAS:7440-23-5 {source="ChemIDplus"} xref: Gmelin:16221 {source="Gmelin"} xref: KEGG:C01330 xref: WebElements:Na is_a: CHEBI:22314 ! alkali metal atom relationship: has_role CHEBI:33937 ! macronutrient relationship: has_role CHEBI:75772 ! Saccharomyces cerevisiae metabolite property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "Na" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/Na" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "KEAYESYHFKHZAL-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "22.98977" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "22.98977" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[Na]" xsd:string [Term] id: CHEBI:26712 name: sodium molecular entity namespace: chebi_ontology subset: 3_STAR synonym: "sodium compounds" RELATED [ChEBI] synonym: "sodium molecular entities" RELATED [ChEBI] is_a: CHEBI:33296 ! alkali metal molecular entity relationship: has_part CHEBI:26708 ! sodium atom [Term] id: CHEBI:26714 name: sodium salt namespace: chebi_ontology def: "Any alkali metal salt having sodium(1+) as the cation." [] subset: 3_STAR synonym: "Natriumsalz" RELATED [ChEBI] synonym: "Natriumsalze" RELATED [ChEBI] synonym: "sodium salts" RELATED [ChEBI] is_a: CHEBI:26712 ! sodium molecular entity is_a: CHEBI:35479 ! alkali metal salt relationship: has_part CHEBI:29101 ! sodium(1+) [Term] id: CHEBI:26764 name: steroid hormone namespace: chebi_ontology def: "Any steroid that acts as hormone." [] subset: 3_STAR synonym: "hormona esteroide" RELATED [ChEBI] synonym: "hormonas esteroideas" RELATED [ChEBI] synonym: "hormone steroide" RELATED [ChEBI] synonym: "hormones steroides" RELATED [ChEBI] synonym: "steroid hormones" RELATED [ChEBI] synonym: "Steroidhormon" RELATED [ChEBI] synonym: "Steroidhormone" RELATED [ChEBI] is_a: CHEBI:35341 ! steroid relationship: has_role CHEBI:24621 ! hormone [Term] id: CHEBI:26819 name: sulfuric ester namespace: chebi_ontology def: "An ester of an alcohol and sulfuric acid." [] subset: 3_STAR synonym: "sulfate ester" RELATED [ChEBI] synonym: "sulfuric acid ester" RELATED [ChEBI] synonym: "sulfuric acid esters" RELATED [ChEBI] is_a: CHEBI:35701 ! ester is_a: CHEBI:37826 ! sulfuric acid derivative property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "O4SR2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "96.06300" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "95.95173" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[*]OS(=O)(=O)O[*]" xsd:string [Term] id: CHEBI:26820 name: sulfates namespace: chebi_ontology def: "Salts and esters of sulfuric acid" [] subset: 3_STAR synonym: "sulfates" EXACT [ChEBI] synonym: "sulfuric acid derivative" RELATED [ChEBI] synonym: "sulphates" RELATED [ChEBI] is_a: CHEBI:37826 ! sulfuric acid derivative [Term] id: CHEBI:26833 name: sulfur atom namespace: chebi_ontology subset: 3_STAR synonym: "16S" RELATED [IUPAC] synonym: "azufre" RELATED [ChEBI] synonym: "Elemental sulfur" RELATED [KEGG_COMPOUND] synonym: "S" RELATED [KEGG_COMPOUND] synonym: "S" RELATED [IUPAC] synonym: "Schwefel" RELATED [ChEBI] synonym: "soufre" RELATED [ChEBI] synonym: "sulfur" EXACT IUPAC_NAME [IUPAC] synonym: "sulfur" RELATED [ChEBI] synonym: "sulfur" RELATED [UniProt] synonym: "sulphur" RELATED [ChEBI] synonym: "theion" RELATED [IUPAC] xref: CAS:7704-34-9 {source="ChemIDplus"} xref: CAS:7704-34-9 {source="NIST Chemistry WebBook"} xref: KEGG:C00087 xref: KEGG:D06527 xref: PPDB:605 xref: WebElements:S is_a: CHEBI:25585 ! nonmetal atom is_a: CHEBI:33303 ! chalcogen relationship: has_role CHEBI:33937 ! macronutrient property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "S" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/S" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "NINIDFKCEFEMDL-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "32.06600" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "31.97207" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[S]" xsd:string [Term] id: CHEBI:26835 name: sulfur molecular entity namespace: chebi_ontology subset: 3_STAR synonym: "sulfur molecular entities" RELATED [ChEBI] synonym: "sulfur molecular entity" EXACT [ChEBI] is_a: CHEBI:33304 ! chalcogen molecular entity relationship: has_part CHEBI:26833 ! sulfur atom [Term] id: CHEBI:26836 name: sulfuric acid namespace: chebi_ontology def: "A sulfur oxoacid that consists of two oxo and two hydroxy groups joined covalently to a central sulfur atom." [] subset: 3_STAR synonym: "[S(OH)2O2]" RELATED [MolBase] synonym: "[SO2(OH)2]" RELATED [IUPAC] synonym: "Acide sulfurique" RELATED [ChemIDplus] synonym: "Acido sulfurico" RELATED [ChemIDplus] synonym: "Acidum sulfuricum" RELATED [ChemIDplus] synonym: "dihydrogen tetraoxosulfate" EXACT IUPAC_NAME [IUPAC] synonym: "dihydroxidodioxidosulfur" EXACT IUPAC_NAME [IUPAC] synonym: "H2SO4" RELATED [IUPAC] synonym: "hydrogen tetraoxosulfate(2-)" EXACT IUPAC_NAME [IUPAC] synonym: "hydrogen tetraoxosulfate(VI)" EXACT IUPAC_NAME [IUPAC] synonym: "Schwefelsaeureloesungen" RELATED [ChemIDplus] synonym: "Sulfuric acid" EXACT [KEGG_COMPOUND] synonym: "sulfuric acid" EXACT IUPAC_NAME [IUPAC] synonym: "sulfuric acid" EXACT [ChEBI] synonym: "sulphuric acid" RELATED [MolBase] synonym: "tetraoxosulfuric acid" EXACT IUPAC_NAME [IUPAC] xref: CAS:7664-93-9 {source="ChemIDplus"} xref: CAS:7664-93-9 {source="KEGG COMPOUND"} xref: CAS:7664-93-9 {source="NIST Chemistry WebBook"} xref: Gmelin:2122 {source="Gmelin"} xref: KEGG:C00059 xref: KEGG:D05963 xref: KNApSAcK:C00007530 xref: MolBase:4 xref: PMID:13568755 {source="Europe PMC"} xref: PMID:16122922 {source="Europe PMC"} xref: PMID:19397353 {source="Europe PMC"} xref: PMID:22047659 {source="Europe PMC"} xref: PMID:22136045 {source="Europe PMC"} xref: PMID:22204399 {source="Europe PMC"} xref: PMID:22267186 {source="Europe PMC"} xref: PMID:22296037 {source="Europe PMC"} xref: PMID:22364556 {source="Europe PMC"} xref: PMID:22435616 {source="Europe PMC"} xref: PPDB:606 xref: Reaxys:2037554 {source="Reaxys"} xref: Wikipedia:Sulfuric_acid is_a: CHEBI:33402 ! sulfur oxoacid relationship: has_role CHEBI:35223 ! catalyst relationship: is_conjugate_acid_of CHEBI:45696 ! hydrogensulfate property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "H2O4S" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QAOWNCQODCNURD-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "98.07948" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "97.96738" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]OS(=O)(=O)O[H]" xsd:string [Term] id: CHEBI:26932 name: tetrapyrrole namespace: chebi_ontology def: "A natural pigment containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next." [] subset: 3_STAR synonym: "a tetrapyrrole" RELATED [UniProt] synonym: "tetrapyrrole" EXACT IUPAC_NAME [IUPAC] synonym: "tetrapyrroles" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:33833 ! heteroarene is_a: CHEBI:38077 ! polypyrrole [Term] id: CHEBI:27027 name: micronutrient namespace: chebi_ontology def: "Any nutrient required in small quantities by organisms throughout their life in order to orchestrate a range of physiological functions." [] subset: 3_STAR synonym: "micronutrients" RELATED [ChEBI] synonym: "trace elements" RELATED [ChEBI] xref: Wikipedia:Micronutrient is_a: CHEBI:33284 ! nutrient [Term] id: CHEBI:27162 name: tryptamines namespace: chebi_ontology def: "Tryptamine and its substitution derivatives." [] subset: 3_STAR is_a: CHEBI:24828 ! indoles [Term] id: CHEBI:27171 name: organic heterobicyclic compound namespace: chebi_ontology subset: 3_STAR synonym: "heterobicyclic compounds" RELATED [ChEBI] synonym: "organic heterobicyclic compounds" RELATED [ChEBI] is_a: CHEBI:33672 ! heterobicyclic compound is_a: CHEBI:38166 ! organic heteropolycyclic compound [Term] id: CHEBI:27207 name: univalent carboacyl group namespace: chebi_ontology def: "A univalent carboacyl group is a group formed by loss of OH from the carboxy group of a carboxylic acid." [] subset: 3_STAR synonym: "univalent acyl group" RELATED [ChEBI] synonym: "univalent carboacyl groups" RELATED [ChEBI] synonym: "univalent carboxylic acyl groups" RELATED [ChEBI] is_a: CHEBI:37838 ! carboacyl group [Term] id: CHEBI:27369 name: zwitterion namespace: chebi_ontology def: "A neutral compound having formal unit electrical charges of opposite sign on non-adjacent atoms. Sometimes referred to as inner salts, dipolar ions (a misnomer)." [] subset: 3_STAR synonym: "compose zwitterionique" RELATED [IUPAC] synonym: "compuestos zwitterionicos" RELATED [IUPAC] synonym: "zwitterion" EXACT IUPAC_NAME [IUPAC] synonym: "zwitteriones" RELATED [IUPAC] synonym: "zwitterionic compounds" RELATED [IUPAC] synonym: "zwitterions" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:51151 ! dipolar compound [Term] id: CHEBI:27594 name: carbon atom namespace: chebi_ontology alt_id: CHEBI:23009 alt_id: CHEBI:3399 subset: 3_STAR synonym: "6C" RELATED [IUPAC] synonym: "C" RELATED [KEGG_COMPOUND] synonym: "C" RELATED [IUPAC] synonym: "Carbon" RELATED [KEGG_COMPOUND] synonym: "carbon" EXACT IUPAC_NAME [IUPAC] synonym: "carbon" RELATED [ChEBI] synonym: "carbone" RELATED [ChEBI] synonym: "carbonium" RELATED [ChEBI] synonym: "carbono" RELATED [ChEBI] synonym: "Kohlenstoff" RELATED [ChEBI] xref: CAS:7440-44-0 {source="ChemIDplus"} xref: CAS:7440-44-0 {source="KEGG COMPOUND"} xref: KEGG:C06265 xref: WebElements:C is_a: CHEBI:25585 ! nonmetal atom is_a: CHEBI:33306 ! carbon group element atom relationship: has_role CHEBI:33937 ! macronutrient property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "OKTJSMMVPCPJKN-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "12.01070" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "12.00000" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[C]" xsd:string [Term] id: CHEBI:28087 name: glycogen namespace: chebi_ontology alt_id: CHEBI:24379 alt_id: CHEBI:5466 def: "A polydisperse, highly branched glucan composed of chains of D-glucopyranose residues in alpha(1->4) glycosidic linkage, joined together by alpha(1->6) glycosidic linkages. A small number of alpha(1->3) glycosidic linkages and some cumulative alpha(1->6) links also may occur. The branches in glycogen typically contain 8 to 12 glucose residues." [] subset: 3_STAR synonym: "animal starch" RELATED [ChemIDplus] synonym: "Glycogen" EXACT [KEGG_COMPOUND] synonym: "liver starch" RELATED [ChemIDplus] synonym: "WURCS=2.0/1,4,3/[a2122h-1a_1-5]/1-1-1-1/a4-b1_b4-c1_b6-d1" RELATED [GlyTouCan] xref: CAS:9005-79-2 {source="KEGG COMPOUND"} xref: CAS:9005-79-2 {source="ChemIDplus"} xref: GlyGen:G99991IU xref: GlyTouCan:G99991IU xref: HMDB:HMDB0000757 xref: KEGG:C00182 xref: MetaCyc:CPD0-971 xref: Wikipedia:Glycogen is_a: CHEBI:24384 ! glycogens relationship: has_role CHEBI:75772 ! Saccharomyces cerevisiae metabolite relationship: has_role CHEBI:76971 ! Escherichia coli metabolite [Term] id: CHEBI:28616 name: carbamic acid namespace: chebi_ontology alt_id: CHEBI:22504 alt_id: CHEBI:23002 alt_id: CHEBI:3386 alt_id: CHEBI:44573 def: "A one-carbon compound that is ammonia in which one of the hydrogens is replaced by a carboxy group. Although carbamic acid derivatives are common, carbamic acid itself has never been synthesised." [] subset: 3_STAR synonym: "Aminoameisensaeure" RELATED [ChEBI] synonym: "Aminoformic acid" RELATED [KEGG_COMPOUND] synonym: "Carbamate" RELATED [KEGG_COMPOUND] synonym: "CARBAMIC ACID" EXACT [PDBeChem] synonym: "Carbamic acid" EXACT [KEGG_COMPOUND] synonym: "carbamic acid" EXACT IUPAC_NAME [IUPAC] synonym: "Carbamidsaeure" RELATED [ChEBI] xref: Beilstein:1734754 {source="Beilstein"} xref: CAS:463-77-4 {source="KEGG COMPOUND"} xref: CAS:463-77-4 {source="ChemIDplus"} xref: DrugBank:DB04261 xref: Gmelin:130345 {source="Gmelin"} xref: KEGG:C01563 xref: PDBeChem:OUT xref: Wikipedia:Carbamic_acid is_a: CHEBI:35352 ! organonitrogen compound is_a: CHEBI:35605 ! carbon oxoacid is_a: CHEBI:64708 ! one-carbon compound relationship: has_role CHEBI:76971 ! Escherichia coli metabolite relationship: is_conjugate_acid_of CHEBI:13941 ! carbamate property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CH3NO2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/CH3NO2/c2-1(3)4/h2H2,(H,3,4)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "KXDHJXZQYSOELW-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "61.04006" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "61.01638" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "NC(O)=O" xsd:string [Term] id: CHEBI:28659 name: phosphorus atom namespace: chebi_ontology alt_id: CHEBI:26080 alt_id: CHEBI:8168 subset: 3_STAR synonym: "15P" RELATED [IUPAC] synonym: "fosforo" RELATED [ChEBI] synonym: "P" RELATED [IUPAC] synonym: "P" RELATED [KEGG_COMPOUND] synonym: "Phosphor" RELATED [ChEBI] synonym: "phosphore" RELATED [ChEBI] synonym: "Phosphorus" RELATED [KEGG_COMPOUND] synonym: "phosphorus" EXACT IUPAC_NAME [IUPAC] synonym: "phosphorus" RELATED [ChEBI] xref: CAS:7723-14-0 {source="ChemIDplus"} xref: CAS:7723-14-0 {source="KEGG COMPOUND"} xref: Gmelin:16235 {source="Gmelin"} xref: KEGG:C06262 xref: WebElements:P is_a: CHEBI:25585 ! nonmetal atom is_a: CHEBI:33300 ! pnictogen relationship: has_role CHEBI:33937 ! macronutrient property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "P" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/P" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "OAICVXFJPJFONN-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "30.97376" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "30.97376" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[P]" xsd:string [Term] id: CHEBI:28790 name: serotonin namespace: chebi_ontology alt_id: CHEBI:1420 alt_id: CHEBI:26652 alt_id: CHEBI:49894 def: "A primary amino compound that is the 5-hydroxy derivative of tryptamine." [] subset: 3_STAR synonym: "3-(2-Aminoethyl)-1H-indol-5-ol" RELATED [KEGG_COMPOUND] synonym: "3-(2-aminoethyl)-1H-indol-5-ol" EXACT IUPAC_NAME [IUPAC] synonym: "5-HT" RELATED [IUPHAR] synonym: "5-Hydroxytryptamine" RELATED [KEGG_COMPOUND] synonym: "Enteramine" RELATED [KEGG_COMPOUND] synonym: "SEROTONIN" EXACT [PDBeChem] synonym: "Serotonin" EXACT [KEGG_COMPOUND] synonym: "serotonine" RELATED [ChEBI] synonym: "thrombocytin" RELATED [ChemIDplus] synonym: "thrombotonin" RELATED [ChemIDplus] xref: Beilstein:143524 {source="Beilstein"} xref: CAS:50-67-9 {source="KEGG COMPOUND"} xref: CAS:50-67-9 {source="ChemIDplus"} xref: Gmelin:1861995 {source="Gmelin"} xref: HMDB:HMDB0000259 xref: KEGG:C00780 xref: KNApSAcK:C00001429 xref: LINCS:LSM-6589 xref: MetaCyc:SEROTONIN xref: PDBeChem:SRO xref: PMID:18593914 {source="Europe PMC"} xref: PMID:22770225 {source="Europe PMC"} xref: PMID:24136337 {source="Europe PMC"} xref: Reaxys:143524 {source="Reaxys"} xref: Wikipedia:Serotonin is_a: CHEBI:25375 ! monoamine molecular messenger is_a: CHEBI:27162 ! tryptamines is_a: CHEBI:33853 ! phenols is_a: CHEBI:50994 ! primary amino compound is_a: CHEBI:84729 ! hydroxyindoles relationship: has_functional_parent CHEBI:16765 ! tryptamine relationship: has_role CHEBI:25512 ! neurotransmitter relationship: has_role CHEBI:75771 ! mouse metabolite relationship: has_role CHEBI:77746 ! human metabolite relationship: is_conjugate_base_of CHEBI:350546 ! serotonin(1+) property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C10H12N2O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QZAYGJVTTNCVMB-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "176.215" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "176.09496" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "C1=CC(=CC=2C(=CNC12)CCN)O" xsd:string [Term] id: CHEBI:28938 name: ammonium namespace: chebi_ontology alt_id: CHEBI:22534 alt_id: CHEBI:49783 alt_id: CHEBI:7435 def: "An onium cation obtained by protonation of ammonia." [] subset: 3_STAR synonym: "[NH4](+)" RELATED [MolBase] synonym: "ammonium" EXACT IUPAC_NAME [IUPAC] synonym: "ammonium" EXACT [ChEBI] synonym: "ammonium cation" RELATED [ChemIDplus] synonym: "ammonium ion" RELATED [PDBeChem] synonym: "Ammonium(1+)" RELATED [ChemIDplus] synonym: "azanium" EXACT IUPAC_NAME [IUPAC] synonym: "NH4(+)" RELATED [UniProt] synonym: "NH4(+)" RELATED [IUPAC] synonym: "NH4+" RELATED [KEGG_COMPOUND] xref: CAS:14798-03-9 {source="NIST Chemistry WebBook"} xref: CAS:14798-03-9 {source="ChemIDplus"} xref: Gmelin:84 {source="Gmelin"} xref: KEGG:C01342 xref: MetaCyc:AMMONIUM xref: MolBase:929 xref: PDBeChem:NH4 xref: PMID:11319011 {source="Europe PMC"} xref: PMID:11341317 {source="Europe PMC"} xref: PMID:12096804 {source="Europe PMC"} xref: PMID:14512268 {source="Europe PMC"} xref: PMID:14879753 {source="Europe PMC"} xref: PMID:16345391 {source="Europe PMC"} xref: PMID:16903292 {source="Europe PMC"} xref: PMID:17392693 {source="Europe PMC"} xref: PMID:18515490 {source="Europe PMC"} xref: PMID:19199063 {source="Europe PMC"} xref: PMID:19596600 {source="Europe PMC"} xref: PMID:19682559 {source="Europe PMC"} xref: PMID:19716251 {source="Europe PMC"} xref: PMID:21993530 {source="Europe PMC"} xref: PMID:22265469 {source="Europe PMC"} xref: PMID:22524020 {source="Europe PMC"} xref: PMID:22562341 {source="Europe PMC"} xref: PMID:22631217 {source="Europe PMC"} xref: Reaxys:16093784 {source="Reaxys"} xref: Wikipedia:Ammonium is_a: CHEBI:35106 ! nitrogen hydride is_a: CHEBI:50313 ! onium cation is_a: CHEBI:60242 ! monovalent inorganic cation relationship: has_role CHEBI:23357 ! cofactor relationship: has_role CHEBI:75772 ! Saccharomyces cerevisiae metabolite relationship: has_role CHEBI:76971 ! Escherichia coli metabolite relationship: has_role CHEBI:77746 ! human metabolite relationship: is_conjugate_acid_of CHEBI:16134 ! ammonia property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "H4N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H3N/h1H3/p+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QGZKDVFQNNGYKY-UHFFFAOYSA-O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "18.03850" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "18.03383" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][N+]([H])([H])[H]" xsd:string [Term] id: CHEBI:28963 name: amino sugar namespace: chebi_ontology alt_id: CHEBI:22481 alt_id: CHEBI:22530 alt_id: CHEBI:2662 def: "Any sugar having one or more alcoholic hydroxy groups replaced by substituted or unsubstituted amino groups." [] subset: 3_STAR synonym: "amino sugars" RELATED [ChEBI] synonym: "aminosugar" RELATED [ChEBI] synonym: "Aminosugars" RELATED [KEGG_COMPOUND] xref: KEGG:C05383 xref: PMID:18424273 {source="Europe PMC"} xref: PMID:9056391 {source="Europe PMC"} is_a: CHEBI:63299 ! carbohydrate derivative [Term] id: CHEBI:28965 name: dicarboxylic acid dianion namespace: chebi_ontology alt_id: CHEBI:13632 alt_id: CHEBI:23688 alt_id: CHEBI:23689 alt_id: CHEBI:38711 def: "A carboxylic acid dianion obtained by deprotonation of both carboxy groups of any dicarboxylic acid." [] subset: 3_STAR synonym: "a dicarboxylate" RELATED [UniProt] synonym: "dicarboxylate" RELATED [ChEBI] synonym: "dicarboxylates" RELATED [ChEBI] synonym: "dicarboxylic acid dianion" EXACT [ChEBI] synonym: "dicarboxylic acid dianions" RELATED [ChEBI] is_a: CHEBI:35693 ! dicarboxylic acid anion is_a: CHEBI:38716 ! carboxylic acid dianion property_value: http://purl.obolibrary.org/obo/chebi/charge "-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C2O4R" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "88.019" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "87.97966" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]C(=O)[*]C([O-])=O" xsd:string [Term] id: CHEBI:28976 name: carbonic acid namespace: chebi_ontology alt_id: CHEBI:13351 alt_id: CHEBI:23017 alt_id: CHEBI:23744 alt_id: CHEBI:3401 subset: 3_STAR synonym: "[CO(OH)2]" RELATED [IUPAC] synonym: "Carbonic acid" EXACT [KEGG_COMPOUND] synonym: "carbonic acid" EXACT IUPAC_NAME [IUPAC] synonym: "Dihydrogen carbonate" RELATED [KEGG_COMPOUND] synonym: "dihydroxidooxidocarbon" EXACT IUPAC_NAME [IUPAC] synonym: "H2CO3" RELATED [KEGG_COMPOUND] synonym: "H2CO3" RELATED [IUPAC] synonym: "Koehlensaeure" RELATED [ChEBI] xref: CAS:463-79-6 {source="ChemIDplus"} xref: CAS:463-79-6 {source="KEGG COMPOUND"} xref: Gmelin:25554 {source="Gmelin"} xref: KEGG:C01353 xref: PDBeChem:CO3 is_a: CHEBI:35605 ! carbon oxoacid is_a: CHEBI:36961 ! chalcocarbonic acid relationship: has_role CHEBI:75771 ! mouse metabolite relationship: is_conjugate_acid_of CHEBI:17544 ! hydrogencarbonate property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CH2O3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "BVKZGUZCCUSVTD-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "62.02478" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "62.00039" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "OC(O)=O" xsd:string [Term] id: CHEBI:29067 name: carboxylic acid anion namespace: chebi_ontology alt_id: CHEBI:13626 alt_id: CHEBI:13945 alt_id: CHEBI:23026 alt_id: CHEBI:58657 def: "The conjugate base formed when the carboxy group of a carboxylic acid is deprotonated." [] subset: 3_STAR synonym: "a carboxylate" RELATED [UniProt] synonym: "carboxylic acid anions" RELATED [ChEBI] synonym: "carboxylic anions" RELATED [ChEBI] is_a: CHEBI:25696 ! organic anion is_a: CHEBI:35406 ! oxoanion relationship: is_conjugate_base_of CHEBI:33575 ! carboxylic acid property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CO2R" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "44.00950" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "43.98983" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]C([*])=O" xsd:string [Term] id: CHEBI:29101 name: sodium(1+) namespace: chebi_ontology alt_id: CHEBI:26717 alt_id: CHEBI:49766 alt_id: CHEBI:9175 def: "A monoatomic monocation obtained from sodium." [] subset: 3_STAR synonym: "Na(+)" RELATED [UniProt] synonym: "Na(+)" RELATED [IUPAC] synonym: "Na+" RELATED [KEGG_COMPOUND] synonym: "sodium cation" EXACT IUPAC_NAME [IUPAC] synonym: "SODIUM ION" RELATED [PDBeChem] synonym: "sodium(1+)" EXACT IUPAC_NAME [IUPAC] synonym: "sodium(1+) ion" EXACT IUPAC_NAME [IUPAC] synonym: "sodium(I) cation" EXACT IUPAC_NAME [IUPAC] xref: CAS:17341-25-2 {source="ChemIDplus"} xref: CAS:17341-25-2 {source="NIST Chemistry WebBook"} xref: Gmelin:15196 {source="Gmelin"} xref: KEGG:C01330 xref: PDBeChem:NA is_a: CHEBI:25414 ! monoatomic monocation is_a: CHEBI:33504 ! alkali metal cation is_a: CHEBI:37246 ! elemental sodium is_a: CHEBI:60242 ! monovalent inorganic cation relationship: has_role CHEBI:23357 ! cofactor relationship: has_role CHEBI:77746 ! human metabolite property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "Na" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/Na/q+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "FKNQFGJONOIPTF-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "22.98977" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "22.98922" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[Na+]" xsd:string [Term] id: CHEBI:29337 name: azanide namespace: chebi_ontology subset: 3_STAR synonym: "amide" EXACT IUPAC_NAME [IUPAC] synonym: "azanide" EXACT IUPAC_NAME [IUPAC] synonym: "dihydridonitrate(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "NH2(-)" RELATED [IUPAC] is_a: CHEBI:35106 ! nitrogen hydride is_a: CHEBI:79389 ! monovalent inorganic anion relationship: is_conjugate_acid_of CHEBI:29340 ! hydridonitrate(2-) relationship: is_conjugate_base_of CHEBI:16134 ! ammonia property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "H2N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H2N/h1H2/q-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "HYGWNUKOUCZBND-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "16.02262" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "16.01927" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][N-][H]" xsd:string [Term] id: CHEBI:29340 name: hydridonitrate(2-) namespace: chebi_ontology def: "A divalent inorganic anion resulting from the removal of two protons from ammonia." [] subset: 3_STAR synonym: "azanediide" EXACT IUPAC_NAME [IUPAC] synonym: "hydridonitrate(2-)" EXACT IUPAC_NAME [IUPAC] synonym: "imide" RELATED [IUPAC] synonym: "NH(2-)" RELATED [IUPAC] is_a: CHEBI:35106 ! nitrogen hydride is_a: CHEBI:79388 ! divalent inorganic anion relationship: is_conjugate_base_of CHEBI:29337 ! azanide property_value: http://purl.obolibrary.org/obo/chebi/charge "-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "HN" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/HN/h1H/q-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "DZQYTNGKSBCIOE-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "15.01468" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "15.01200" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[N--][H]" xsd:string [Term] id: CHEBI:29793 name: hydridodioxygen(1+) namespace: chebi_ontology subset: 3_STAR synonym: "[HO2](+)" RELATED [ChEBI] synonym: "dioxidenium" EXACT IUPAC_NAME [IUPAC] synonym: "HO2(+)" RELATED [IUPAC] synonym: "HOO(+)" RELATED [ChEBI] synonym: "hydridodioxygen(1+)" EXACT IUPAC_NAME [IUPAC] xref: Gmelin:508 {source="Gmelin"} is_a: CHEBI:33693 ! oxygen hydride relationship: is_conjugate_acid_of CHEBI:15379 ! dioxygen property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "HO2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/O2/c1-2/p+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "MYMOFIZGZYHOMD-UHFFFAOYSA-O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "33.00674" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "32.99711" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][O+]=O" xsd:string [Term] id: CHEBI:30089 name: acetate namespace: chebi_ontology alt_id: CHEBI:13704 alt_id: CHEBI:22165 alt_id: CHEBI:40480 def: "A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of acetic acid." [] subset: 3_STAR synonym: "acetate" EXACT [UniProt] synonym: "acetate" EXACT IUPAC_NAME [IUPAC] synonym: "ACETATE ION" RELATED [PDBeChem] synonym: "acetic acid, ion(1-)" RELATED [ChemIDplus] synonym: "Azetat" RELATED [ChEBI] synonym: "CH3-COO(-)" RELATED [IUPAC] synonym: "Ethanoat" RELATED [ChEBI] synonym: "ethanoate" RELATED [ChEBI] synonym: "MeCO2 anion" RELATED [NIST_Chemistry_WebBook] xref: Beilstein:1901470 {source="Beilstein"} xref: CAS:71-50-1 {source="ChemIDplus"} xref: CAS:71-50-1 {source="NIST Chemistry WebBook"} xref: DrugBank:DB03166 xref: Gmelin:1379 {source="Gmelin"} xref: KEGG:C00033 xref: MetaCyc:ACET xref: PDBeChem:ACT xref: PMID:17190852 {source="Europe PMC"} xref: PMID:22211106 {source="Europe PMC"} xref: PMID:22371380 {source="Europe PMC"} xref: Reaxys:1901470 {source="Reaxys"} xref: UM-BBD_compID:c0050 {source="UM-BBD"} xref: Wikipedia:Acetate is_a: CHEBI:35757 ! monocarboxylic acid anion relationship: has_role CHEBI:75772 ! Saccharomyces cerevisiae metabolite relationship: has_role CHEBI:77746 ! human metabolite relationship: is_conjugate_base_of CHEBI:15366 ! acetic acid property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H3O2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)/p-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QTBSBXVTEAMEQO-UHFFFAOYSA-M" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "59.04402" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "59.01385" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CC([O-])=O" xsd:string [Term] id: CHEBI:30212 name: photon namespace: chebi_ontology alt_id: CHEBI:10581 alt_id: CHEBI:14383 def: "Particle of zero charge, zero rest mass, spin quantum number 1, energy hnu and momentum hnu/c (h is the Planck constant, nu the frequency of radiation and c the speed of light), carrier of electromagnetic force." [] subset: 3_STAR synonym: "foton" RELATED [ChEBI] synonym: "gamma" RELATED [IUPAC] synonym: "hnu" RELATED [IUPAC] synonym: "hnu" RELATED [UniProt] synonym: "Lichtquant" RELATED [ChEBI] synonym: "Light" RELATED [KEGG_COMPOUND] synonym: "light quantum" RELATED [ChEBI] synonym: "photon" EXACT IUPAC_NAME [IUPAC] xref: KEGG:C00205 is_a: CHEBI:36341 ! boson property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "0.0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "0.0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "*" xsd:string [Term] id: CHEBI:3098 name: bile acid namespace: chebi_ontology def: "Any member of a group of hydroxy-5beta-cholanic acids occuring in bile, where they are present as the sodium salts of their amides with glycine or taurine. In mammals bile acids almost invariably have 5beta-configuration." [] subset: 3_STAR synonym: "5beta-bile acid" RELATED [ChEBI] synonym: "5beta-bile acids" RELATED [ChEBI] synonym: "Bile acid" EXACT [KEGG_COMPOUND] synonym: "bile acids" RELATED [ChEBI] synonym: "Bile salt" RELATED [KEGG_COMPOUND] synonym: "Gallensaeure" RELATED [ChEBI] synonym: "Gallensaeuren" RELATED [ChEBI] xref: KEGG:C01558 is_a: CHEBI:138366 ! bile acids is_a: CHEBI:24663 ! hydroxy-5beta-cholanic acid [Term] id: CHEBI:32952 name: amine namespace: chebi_ontology alt_id: CHEBI:13814 alt_id: CHEBI:22474 alt_id: CHEBI:2641 def: "A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups." [] subset: 3_STAR synonym: "Amin" RELATED [ChEBI] synonym: "Amine" EXACT [KEGG_COMPOUND] synonym: "amines" EXACT IUPAC_NAME [IUPAC] synonym: "Substituted amine" RELATED [KEGG_COMPOUND] xref: KEGG:C00706 is_a: CHEBI:50047 ! organic amino compound [Term] id: CHEBI:32988 name: amide namespace: chebi_ontology alt_id: CHEBI:22473 alt_id: CHEBI:2633 def: "An amide is a derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group." [] subset: 3_STAR synonym: "Amide" EXACT [KEGG_COMPOUND] synonym: "amides" EXACT IUPAC_NAME [IUPAC] xref: KEGG:C00241 is_a: CHEBI:51143 ! nitrogen molecular entity [Term] id: CHEBI:33232 name: application namespace: chebi_ontology def: "Intended use of the molecular entity or part thereof by humans." [] subset: 3_STAR is_a: CHEBI:50906 ! role [Term] id: CHEBI:33233 name: fundamental particle namespace: chebi_ontology def: "A particle not known to have substructure." [] subset: 3_STAR synonym: "elementary particle" EXACT IUPAC_NAME [IUPAC] synonym: "elementary particles" RELATED [ChEBI] is_a: CHEBI:36342 ! subatomic particle [Term] id: CHEBI:33238 name: monoatomic entity namespace: chebi_ontology def: "A monoatomic entity is a molecular entity consisting of a single atom." [] subset: 3_STAR synonym: "atomic entity" RELATED [ChEBI] synonym: "monoatomic entities" RELATED [ChEBI] is_a: CHEBI:33259 ! elemental molecular entity [Term] id: CHEBI:33241 name: oxoacid derivative namespace: chebi_ontology subset: 3_STAR synonym: "oxoacid derivatives" RELATED [ChEBI] is_a: CHEBI:37577 ! heteroatomic molecular entity relationship: has_functional_parent CHEBI:24833 ! oxoacid [Term] id: CHEBI:33242 name: inorganic hydride namespace: chebi_ontology subset: 3_STAR synonym: "inorganic hydrides" RELATED [ChEBI] is_a: CHEBI:24835 ! inorganic molecular entity is_a: CHEBI:33692 ! hydrides [Term] id: CHEBI:33245 name: organic fundamental parent namespace: chebi_ontology def: "An organic fundamental parent is a structure used as a basis for substitutive names in organic nomenclature, containing, in addition to one or more hydrogen atoms, a single atom of an element, a number of atoms (alike or different) linked together to form an unbranched chain, a monocyclic or polycyclic ring system, or a ring assembly or ring/chain system." [] subset: 3_STAR synonym: "organic fundamental parents" RELATED [ChEBI] synonym: "organic parent hydrides" RELATED [ChEBI] is_a: CHEBI:37175 ! organic hydride is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:33246 name: inorganic group namespace: chebi_ontology def: "Any substituent group which does not contain carbon." [] subset: 3_STAR synonym: "inorganic groups" RELATED [ChEBI] is_a: CHEBI:24433 ! group [Term] id: CHEBI:33247 name: organic group namespace: chebi_ontology def: "Any substituent group or skeleton containing carbon." [] subset: 3_STAR synonym: "organic groups" RELATED [ChEBI] is_a: CHEBI:23367 ! molecular entity is_a: CHEBI:24433 ! group relationship: is_substituent_group_from CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:33249 name: organyl group namespace: chebi_ontology def: "Any organic substituent group, regardless of functional type, having one free valence at a carbon atom." [] subset: 3_STAR synonym: "groupe organyle" RELATED [IUPAC] synonym: "grupo organilo" RELATED [IUPAC] synonym: "grupos organilo" RELATED [IUPAC] synonym: "organyl group" EXACT IUPAC_NAME [IUPAC] synonym: "organyl groups" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:51447 ! organic univalent group [Term] id: CHEBI:33250 name: atom namespace: chebi_ontology alt_id: CHEBI:22671 alt_id: CHEBI:23907 def: "A chemical entity constituting the smallest component of an element having the chemical properties of the element." [] subset: 3_STAR synonym: "atom" EXACT IUPAC_NAME [IUPAC] synonym: "atome" RELATED [IUPAC] synonym: "atomo" RELATED [IUPAC] synonym: "atoms" RELATED [ChEBI] synonym: "atomus" RELATED [ChEBI] synonym: "element" RELATED [ChEBI] synonym: "elements" RELATED [ChEBI] is_a: CHEBI:24431 ! chemical entity relationship: has_part CHEBI:10545 ! electron relationship: has_part CHEBI:33252 ! atomic nucleus [Term] id: CHEBI:33252 name: atomic nucleus namespace: chebi_ontology def: "A nucleus is the positively charged central portion of an atom, excluding the orbital electrons." [] subset: 3_STAR synonym: "Atomkern" RELATED [ChEBI] synonym: "Kern" RELATED [ChEBI] synonym: "noyau" RELATED [IUPAC] synonym: "noyau atomique" RELATED [ChEBI] synonym: "nuclei" RELATED [ChEBI] synonym: "nucleo" RELATED [IUPAC] synonym: "nucleo atomico" RELATED [ChEBI] synonym: "nucleus" EXACT IUPAC_NAME [IUPAC] synonym: "nucleus atomi" RELATED [ChEBI] is_a: CHEBI:36347 ! nuclear particle relationship: has_part CHEBI:33253 ! nucleon [Term] id: CHEBI:33253 name: nucleon namespace: chebi_ontology def: "Heavy nuclear particle: proton or neutron." [] subset: 3_STAR synonym: "nucleon" EXACT [IUPAC] synonym: "nucleon" EXACT IUPAC_NAME [IUPAC] synonym: "nucleons" RELATED [ChEBI] synonym: "Nukleon" RELATED [ChEBI] synonym: "Nukleonen" RELATED [ChEBI] is_a: CHEBI:36339 ! baryon is_a: CHEBI:36347 ! nuclear particle [Term] id: CHEBI:33256 name: primary amide namespace: chebi_ontology def: "A derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group." [] subset: 3_STAR synonym: "primary amide" EXACT [IUPAC] synonym: "primary amides" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:32988 ! amide [Term] id: CHEBI:33259 name: elemental molecular entity namespace: chebi_ontology def: "A molecular entity all atoms of which have the same atomic number." [] subset: 3_STAR synonym: "homoatomic entity" RELATED [ChEBI] synonym: "homoatomic molecular entities" RELATED [ChEBI] synonym: "homoatomic molecular entity" RELATED [ChEBI] is_a: CHEBI:23367 ! molecular entity [Term] id: CHEBI:33262 name: elemental oxygen namespace: chebi_ontology subset: 3_STAR is_a: CHEBI:24835 ! inorganic molecular entity is_a: CHEBI:25806 ! oxygen molecular entity is_a: CHEBI:33259 ! elemental molecular entity [Term] id: CHEBI:33263 name: diatomic oxygen namespace: chebi_ontology subset: 3_STAR is_a: CHEBI:33262 ! elemental oxygen property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "O2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "31.999" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "31.98983" xsd:string [Term] id: CHEBI:33273 name: polyatomic anion namespace: chebi_ontology def: "An anion consisting of more than one atom." [] subset: 3_STAR synonym: "polyatomic anions" RELATED [ChEBI] is_a: CHEBI:22563 ! anion is_a: CHEBI:36358 ! polyatomic ion [Term] id: CHEBI:33280 name: molecular messenger namespace: chebi_ontology subset: 3_STAR synonym: "chemical messenger" RELATED [ChEBI] is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:33281 name: antimicrobial agent namespace: chebi_ontology alt_id: CHEBI:22582 def: "A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans." [] subset: 3_STAR synonym: "antibiotic" RELATED [ChEBI] synonym: "antibiotics" RELATED [ChEBI] synonym: "Antibiotika" RELATED [ChEBI] synonym: "Antibiotikum" RELATED [ChEBI] synonym: "antibiotique" RELATED [IUPAC] synonym: "antimicrobial" RELATED [ChEBI] synonym: "antimicrobial agents" RELATED [ChEBI] synonym: "antimicrobials" RELATED [ChEBI] synonym: "microbicide" RELATED [ChEBI] synonym: "microbicides" RELATED [ChEBI] xref: PMID:12964249 {source="Europe PMC"} xref: PMID:22117953 {source="Europe PMC"} xref: PMID:22439833 {source="Europe PMC"} xref: PMID:22849268 {source="Europe PMC"} xref: PMID:22849276 {source="Europe PMC"} xref: PMID:22958833 {source="Europe PMC"} is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:33284 name: nutrient namespace: chebi_ontology def: "A nutrient is a food component that an organism uses to survive and grow." [] subset: 3_STAR synonym: "nutrients" RELATED [ChEBI] is_a: CHEBI:78295 ! food component [Term] id: CHEBI:33285 name: heteroorganic entity namespace: chebi_ontology def: "A heteroorganic entity is an organic molecular entity in which carbon atoms or organic groups are bonded directly to one or more heteroatoms." [] subset: 3_STAR synonym: "heteroorganic entities" RELATED [ChEBI] synonym: "organoelement compounds" RELATED [ChEBI] is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:33286 name: agrochemical namespace: chebi_ontology def: "An agrochemical is a substance that is used in agriculture or horticulture." [] subset: 3_STAR synonym: "agrichemical" RELATED [ChEBI] synonym: "agrichemicals" RELATED [ChEBI] synonym: "agricultural chemicals" RELATED [ChEBI] synonym: "agrochemicals" RELATED [ChEBI] xref: Wikipedia:Agrochemical is_a: CHEBI:33232 ! application [Term] id: CHEBI:33287 name: fertilizer namespace: chebi_ontology def: "A fertilizer is any substance that is added to soil or water to assist the growth of plants." [] subset: 3_STAR synonym: "fertiliser" RELATED [ChEBI] synonym: "fertilizers" RELATED [ChEBI] is_a: CHEBI:33286 ! agrochemical [Term] id: CHEBI:33296 name: alkali metal molecular entity namespace: chebi_ontology def: "A molecular entity containing one or more atoms of an alkali metal." [] subset: 3_STAR synonym: "alkali metal molecular entities" RELATED [ChEBI] is_a: CHEBI:33674 ! s-block molecular entity relationship: has_part CHEBI:22314 ! alkali metal atom [Term] id: CHEBI:33300 name: pnictogen namespace: chebi_ontology def: "Any p-block element atom that is in group 15 of the periodic table: nitrogen, phosphorus, arsenic, antimony and bismuth." [] subset: 3_STAR synonym: "group 15 elements" RELATED [ChEBI] synonym: "group V elements" RELATED [ChEBI] synonym: "nitrogenoideos" RELATED [ChEBI] synonym: "nitrogenoides" RELATED [ChEBI] synonym: "pnictogene" RELATED [ChEBI] synonym: "pnictogenes" RELATED [ChEBI] synonym: "pnictogens" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:33560 ! p-block element atom [Term] id: CHEBI:33302 name: pnictogen molecular entity namespace: chebi_ontology def: "A p-block molecular entity containing any pnictogen." [] subset: 3_STAR synonym: "pnictogen molecular entities" RELATED [ChEBI] synonym: "pnictogen molecular entity" EXACT [ChEBI] is_a: CHEBI:33675 ! p-block molecular entity relationship: has_part CHEBI:33300 ! pnictogen [Term] id: CHEBI:33303 name: chalcogen namespace: chebi_ontology def: "Any p-block element belonging to the group 16 family of the periodic table." [] subset: 3_STAR synonym: "anfigeno" RELATED [ChEBI] synonym: "anfigenos" RELATED [ChEBI] synonym: "calcogeno" RELATED [ChEBI] synonym: "calcogenos" RELATED [ChEBI] synonym: "chalcogen" EXACT IUPAC_NAME [IUPAC] synonym: "chalcogene" RELATED [ChEBI] synonym: "chalcogenes" RELATED [ChEBI] synonym: "chalcogens" EXACT IUPAC_NAME [IUPAC] synonym: "Chalkogen" RELATED [ChEBI] synonym: "Chalkogene" RELATED [ChEBI] synonym: "group 16 elements" RELATED [ChEBI] synonym: "group VI elements" RELATED [ChEBI] xref: PMID:17084588 {source="Europe PMC"} is_a: CHEBI:33560 ! p-block element atom [Term] id: CHEBI:33304 name: chalcogen molecular entity namespace: chebi_ontology def: "Any p-block molecular entity containing a chalcogen." [] subset: 3_STAR synonym: "chalcogen compounds" RELATED [ChEBI] synonym: "chalcogen molecular entities" RELATED [ChEBI] synonym: "chalcogen molecular entity" EXACT [ChEBI] is_a: CHEBI:33675 ! p-block molecular entity relationship: has_part CHEBI:33303 ! chalcogen [Term] id: CHEBI:33306 name: carbon group element atom namespace: chebi_ontology subset: 3_STAR synonym: "carbon group element" RELATED [ChEBI] synonym: "carbon group elements" RELATED [ChEBI] synonym: "carbonoides" RELATED [ChEBI] synonym: "cristallogene" RELATED [ChEBI] synonym: "cristallogenes" RELATED [ChEBI] synonym: "group 14 elements" EXACT IUPAC_NAME [IUPAC] synonym: "group IV elements" RELATED [ChEBI] is_a: CHEBI:33560 ! p-block element atom [Term] id: CHEBI:33308 name: carboxylic ester namespace: chebi_ontology alt_id: CHEBI:13204 alt_id: CHEBI:23028 alt_id: CHEBI:3408 def: "An ester of a carboxylic acid, R(1)C(=O)OR(2), where R(1) = H or organyl and R(2) = organyl." [] subset: 3_STAR synonym: "a carboxylic ester" RELATED [UniProt] synonym: "carboxylic acid esters" RELATED [ChEBI] synonym: "Carboxylic ester" EXACT [KEGG_COMPOUND] synonym: "carboxylic esters" EXACT IUPAC_NAME [IUPAC] xref: KEGG:C02391 xref: Wikipedia:Ester is_a: CHEBI:35701 ! ester is_a: CHEBI:36586 ! carbonyl compound property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CO2R2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "44.010" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "43.98983" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[*]C(=O)O[*]" xsd:string [Term] id: CHEBI:33318 name: main group element atom namespace: chebi_ontology def: "An atom belonging to one of the main groups (found in the s- and p- blocks) of the periodic table." [] subset: 3_STAR synonym: "Hauptgruppenelement" RELATED [ChEBI] synonym: "Hauptgruppenelemente" RELATED [ChEBI] synonym: "main group element" RELATED [ChEBI] synonym: "main group elements" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:33250 ! atom [Term] id: CHEBI:33402 name: sulfur oxoacid namespace: chebi_ontology subset: 3_STAR synonym: "oxoacids of sulfur" RELATED [ChEBI] synonym: "sulfur oxoacids" RELATED [ChEBI] is_a: CHEBI:26835 ! sulfur molecular entity is_a: CHEBI:33484 ! chalcogen oxoacid [Term] id: CHEBI:33408 name: pnictogen oxoacid namespace: chebi_ontology subset: 3_STAR synonym: "pnictogen oxoacids" RELATED [ChEBI] is_a: CHEBI:24833 ! oxoacid is_a: CHEBI:33302 ! pnictogen molecular entity relationship: has_role CHEBI:138103 ! inorganic acid [Term] id: CHEBI:33424 name: sulfur oxoacid derivative namespace: chebi_ontology subset: 3_STAR synonym: "sulfur oxoacid derivative" EXACT [ChEBI] synonym: "sulfur oxoacid derivatives" RELATED [ChEBI] is_a: CHEBI:26835 ! sulfur molecular entity is_a: CHEBI:33241 ! oxoacid derivative [Term] id: CHEBI:33457 name: phosphorus oxoacid namespace: chebi_ontology def: "A pnictogen oxoacid which contains phosphorus and oxygen, at least one hydrogen atom bound to oxygen, and forms an ion by the loss of one or more protons." [] subset: 3_STAR synonym: "oxoacids of phosphorus" RELATED [ChEBI] synonym: "Oxosaeure des Phosphors" RELATED [ChEBI] synonym: "phosphorus oxoacid" EXACT [ChEBI] synonym: "phosphorus oxoacids" RELATED [ChEBI] is_a: CHEBI:33408 ! pnictogen oxoacid is_a: CHEBI:36360 ! phosphorus oxoacids and derivatives [Term] id: CHEBI:33459 name: pnictogen oxoanion namespace: chebi_ontology subset: 3_STAR synonym: "pnictogen oxoanion" EXACT [ChEBI] synonym: "pnictogen oxoanions" RELATED [ChEBI] is_a: CHEBI:33302 ! pnictogen molecular entity is_a: CHEBI:35406 ! oxoanion [Term] id: CHEBI:33461 name: phosphorus oxoanion namespace: chebi_ontology subset: 3_STAR synonym: "oxoanions of phosphorus" RELATED [ChEBI] synonym: "phosphorus oxoanion" EXACT [ChEBI] synonym: "phosphorus oxoanions" RELATED [ChEBI] is_a: CHEBI:24834 ! inorganic anion is_a: CHEBI:26082 ! phosphorus molecular entity is_a: CHEBI:33459 ! pnictogen oxoanion [Term] id: CHEBI:33482 name: sulfur oxoanion namespace: chebi_ontology subset: 3_STAR synonym: "oxoanions of sulfur" RELATED [ChEBI] synonym: "sulfur oxoanion" EXACT [ChEBI] synonym: "sulfur oxoanions" RELATED [ChEBI] is_a: CHEBI:26835 ! sulfur molecular entity is_a: CHEBI:33485 ! chalcogen oxoanion [Term] id: CHEBI:33484 name: chalcogen oxoacid namespace: chebi_ontology subset: 3_STAR synonym: "chalcogen oxoacid" EXACT [ChEBI] synonym: "chalcogen oxoacids" RELATED [ChEBI] is_a: CHEBI:24833 ! oxoacid relationship: has_role CHEBI:138103 ! inorganic acid [Term] id: CHEBI:33485 name: chalcogen oxoanion namespace: chebi_ontology subset: 3_STAR synonym: "chalcogen oxoanion" EXACT [ChEBI] synonym: "chalcogen oxoanions" RELATED [ChEBI] is_a: CHEBI:35406 ! oxoanion [Term] id: CHEBI:33504 name: alkali metal cation namespace: chebi_ontology subset: 3_STAR synonym: "alkali metal cations" RELATED [ChEBI] is_a: CHEBI:25213 ! metal cation [Term] id: CHEBI:33521 name: metal atom namespace: chebi_ontology alt_id: CHEBI:25217 alt_id: CHEBI:6788 def: "An atom of an element that exhibits typical metallic properties, being typically shiny, with high electrical and thermal conductivity." [] subset: 3_STAR synonym: "elemental metal" RELATED [ChEBI] synonym: "elemental metals" RELATED [ChEBI] synonym: "metal element" RELATED [ChEBI] synonym: "metal elements" RELATED [ChEBI] synonym: "metals" RELATED [ChEBI] xref: KEGG:C00050 xref: PMID:21784043 {source="Europe PMC"} xref: Wikipedia:Metal is_a: CHEBI:33250 ! atom [Term] id: CHEBI:33558 name: alpha-amino-acid anion namespace: chebi_ontology def: "An amino-acid anion obtained by deprotonation of any alpha-amino acid." [] subset: 3_STAR synonym: "alpha-amino acid anions" RELATED [ChEBI] synonym: "alpha-amino-acid anion" EXACT [ChEBI] synonym: "alpha-amino-acid anions" RELATED [ChEBI] is_a: CHEBI:37022 ! amino-acid anion relationship: is_conjugate_base_of CHEBI:33704 ! alpha-amino acid [Term] id: CHEBI:33559 name: s-block element atom namespace: chebi_ontology subset: 3_STAR synonym: "s-block element" RELATED [ChEBI] synonym: "s-block elements" RELATED [ChEBI] is_a: CHEBI:33250 ! atom [Term] id: CHEBI:33560 name: p-block element atom namespace: chebi_ontology def: "Any main group element atom belonging to the p-block of the periodic table." [] subset: 3_STAR synonym: "p-block element" RELATED [ChEBI] synonym: "p-block elements" RELATED [ChEBI] is_a: CHEBI:33318 ! main group element atom [Term] id: CHEBI:33566 name: catechols namespace: chebi_ontology alt_id: CHEBI:134187 alt_id: CHEBI:13628 alt_id: CHEBI:18862 def: "Any compound containing an o-diphenol component." [] subset: 3_STAR synonym: "1,2-benzenediols" RELATED [ChEBI] synonym: "a catechol" RELATED [UniProt] synonym: "benzene-1,2-diols" RELATED [ChEBI] xref: KEGG:C15571 is_a: CHEBI:33570 ! benzenediols property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C6H2O2R4" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "106.079" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "106.00548" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "OC1=C(O)C(*)=C(*)C(*)=C1*" xsd:string [Term] id: CHEBI:33567 name: catecholamine namespace: chebi_ontology alt_id: CHEBI:23056 alt_id: CHEBI:3468 def: "4-(2-Aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution." [] subset: 3_STAR synonym: "Catecholamine" EXACT [KEGG_COMPOUND] synonym: "catecholamines" EXACT IUPAC_NAME [IUPAC] synonym: "catecholamines" RELATED [ChEBI] xref: KEGG:C02012 is_a: CHEBI:25375 ! monoamine molecular messenger is_a: CHEBI:33566 ! catechols property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C8H9NO2R2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "151.163" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "151.06333" xsd:string [Term] id: CHEBI:33569 name: noradrenaline namespace: chebi_ontology def: "A catecholamine in which C-1 of the aminoethyl side-chain is hydroxy-substituted." [] subset: 3_STAR synonym: "4-(2-amino-1-hydroxyethyl)benzene-1,2-diol" EXACT IUPAC_NAME [IUPAC] synonym: "noradrenalina" RELATED [ChEBI] synonym: "norepinephrine" RELATED [ChEBI] xref: Beilstein:2210994 {source="Beilstein"} xref: CAS:138-65-8 {source="NIST Chemistry WebBook"} xref: CAS:138-65-8 {source="ChemIDplus"} xref: Gmelin:863925 {source="Gmelin"} xref: LINCS:LSM-5181 is_a: CHEBI:33567 ! catecholamine relationship: has_role CHEBI:76967 ! human xenobiotic metabolite relationship: is_conjugate_base_of CHEBI:166902 ! noradrenaline(1+) property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C8H11NO3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "SFLSHLFXELFNJZ-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "169.17788" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "169.07389" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "NCC(O)c1ccc(O)c(O)c1" xsd:string [Term] id: CHEBI:33570 name: benzenediols namespace: chebi_ontology alt_id: CHEBI:22705 alt_id: CHEBI:22711 subset: 3_STAR is_a: CHEBI:33853 ! phenols [Term] id: CHEBI:33571 name: (S)-noradrenaline namespace: chebi_ontology def: "The S-enantiomer of noradrenaline." [] subset: 3_STAR synonym: "4-[(1S)-2-amino-1-hydroxyethyl]benzene-1,2-diol" EXACT IUPAC_NAME [IUPAC] xref: Beilstein:2937999 {source="Beilstein"} xref: LINCS:LSM-37072 xref: Reaxys:2937999 {source="Reaxys"} is_a: CHEBI:33569 ! noradrenaline relationship: is_enantiomer_of CHEBI:18357 ! (R)-noradrenaline property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C8H11NO3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m1/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "SFLSHLFXELFNJZ-MRVPVSSYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "169.17788" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "169.07389" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "NC[C@@H](O)c1ccc(O)c(O)c1" xsd:string [Term] id: CHEBI:33575 name: carboxylic acid namespace: chebi_ontology alt_id: CHEBI:13428 alt_id: CHEBI:13627 alt_id: CHEBI:23027 def: "A carbon oxoacid acid carrying at least one -C(=O)OH group and having the structure RC(=O)OH, where R is any any monovalent functional group. Carboxylic acids are the most common type of organic acid." [] subset: 3_STAR synonym: "acide carboxylique" RELATED [IUPAC] synonym: "acides carboxyliques" RELATED [IUPAC] synonym: "acido carboxilico" RELATED [IUPAC] synonym: "acidos carboxilicos" RELATED [IUPAC] synonym: "Carbonsaeure" RELATED [ChEBI] synonym: "Carbonsaeuren" RELATED [ChEBI] synonym: "carboxylic acid" EXACT IUPAC_NAME [IUPAC] synonym: "carboxylic acids" EXACT IUPAC_NAME [IUPAC] synonym: "Karbonsaeure" RELATED [ChEBI] synonym: "RC(=O)OH" RELATED [IUPAC] xref: PMID:17147560 {source="Europe PMC"} xref: PMID:18433345 {source="Europe PMC"} xref: Wikipedia:Carboxylic_acid is_a: CHEBI:35605 ! carbon oxoacid is_a: CHEBI:36586 ! carbonyl compound is_a: CHEBI:64709 ! organic acid relationship: has_part CHEBI:46883 ! carboxy group relationship: is_conjugate_acid_of CHEBI:29067 ! carboxylic acid anion property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CHO2R" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "45.01740" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "44.99765" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "OC([*])=O" xsd:string [Term] id: CHEBI:33579 name: main group molecular entity namespace: chebi_ontology def: "A molecular entity containing one or more atoms from any of groups 1, 2, 13, 14, 15, 16, 17, and 18 of the periodic table." [] subset: 3_STAR synonym: "main group compounds" RELATED [ChEBI] synonym: "main group molecular entities" RELATED [ChEBI] is_a: CHEBI:23367 ! molecular entity relationship: has_part CHEBI:33318 ! main group element atom [Term] id: CHEBI:33582 name: carbon group molecular entity namespace: chebi_ontology subset: 3_STAR synonym: "carbon group molecular entities" RELATED [ChEBI] synonym: "carbon group molecular entity" EXACT [ChEBI] is_a: CHEBI:33675 ! p-block molecular entity relationship: has_part CHEBI:33306 ! carbon group element atom [Term] id: CHEBI:33595 name: cyclic compound namespace: chebi_ontology def: "Any molecule that consists of a series of atoms joined together to form a ring." [] subset: 3_STAR synonym: "cyclic compounds" RELATED [ChEBI] xref: Wikipedia:Cyclic_compound is_a: CHEBI:25367 ! molecule [Term] id: CHEBI:33608 name: hydrogen molecular entity namespace: chebi_ontology subset: 3_STAR synonym: "hydrogen compounds" RELATED [ChEBI] synonym: "hydrogen molecular entities" RELATED [ChEBI] is_a: CHEBI:33674 ! s-block molecular entity relationship: has_part CHEBI:49637 ! hydrogen atom [Term] id: CHEBI:33635 name: polycyclic compound namespace: chebi_ontology subset: 3_STAR synonym: "polycyclic compounds" RELATED [ChEBI] is_a: CHEBI:33595 ! cyclic compound [Term] id: CHEBI:33636 name: bicyclic compound namespace: chebi_ontology def: "A molecule that features two fused rings." [] subset: 3_STAR synonym: "bicyclic compounds" RELATED [ChEBI] is_a: CHEBI:33595 ! cyclic compound [Term] id: CHEBI:33655 name: aromatic compound namespace: chebi_ontology def: "A cyclically conjugated molecular entity with a stability (due to delocalization) significantly greater than that of a hypothetical localized structure (e.g. Kekule structure) is said to possess aromatic character." [] subset: 3_STAR synonym: "aromatic compounds" EXACT IUPAC_NAME [IUPAC] synonym: "aromatic molecular entity" EXACT IUPAC_NAME [IUPAC] synonym: "aromatics" RELATED [ChEBI] synonym: "aromatische Verbindungen" RELATED [ChEBI] is_a: CHEBI:33595 ! cyclic compound [Term] id: CHEBI:33659 name: organic aromatic compound namespace: chebi_ontology subset: 3_STAR synonym: "organic aromatic compounds" RELATED [ChEBI] is_a: CHEBI:33655 ! aromatic compound is_a: CHEBI:33832 ! organic cyclic compound [Term] id: CHEBI:33671 name: heteropolycyclic compound namespace: chebi_ontology def: "A polycyclic compound in which at least one of the rings contains at least one non-carbon atom." [] subset: 3_STAR synonym: "heteropolycyclic compounds" EXACT IUPAC_NAME [IUPAC] synonym: "polyheterocyclic compounds" RELATED [ChEBI] is_a: CHEBI:33635 ! polycyclic compound is_a: CHEBI:5686 ! heterocyclic compound [Term] id: CHEBI:33672 name: heterobicyclic compound namespace: chebi_ontology def: "A bicyclic compound in which at least one of the rings contains at least one skeletal heteroatom." [] subset: 3_STAR synonym: "heterobicyclic compounds" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:33636 ! bicyclic compound is_a: CHEBI:5686 ! heterocyclic compound [Term] id: CHEBI:33674 name: s-block molecular entity namespace: chebi_ontology def: "An s-block molecular entity is a molecular entity containing one or more atoms of an s-block element." [] subset: 3_STAR synonym: "s-block compounds" RELATED [ChEBI] synonym: "s-block molecular entities" RELATED [ChEBI] synonym: "s-block molecular entity" EXACT [ChEBI] is_a: CHEBI:33579 ! main group molecular entity relationship: has_part CHEBI:33559 ! s-block element atom [Term] id: CHEBI:33675 name: p-block molecular entity namespace: chebi_ontology def: "A main group molecular entity that contains one or more atoms of a p-block element." [] subset: 3_STAR synonym: "p-block compounds" RELATED [ChEBI] synonym: "p-block molecular entities" RELATED [ChEBI] synonym: "p-block molecular entitiy" RELATED [ChEBI] is_a: CHEBI:33579 ! main group molecular entity relationship: has_part CHEBI:33560 ! p-block element atom [Term] id: CHEBI:33692 name: hydrides namespace: chebi_ontology def: "Hydrides are chemical compounds of hydrogen with other chemical elements." [] subset: 3_STAR is_a: CHEBI:33608 ! hydrogen molecular entity is_a: CHEBI:37577 ! heteroatomic molecular entity [Term] id: CHEBI:33693 name: oxygen hydride namespace: chebi_ontology subset: 3_STAR synonym: "hydrides of oxygen" RELATED [ChEBI] synonym: "oxygen hydride" EXACT [ChEBI] synonym: "oxygen hydrides" RELATED [ChEBI] is_a: CHEBI:36902 ! chalcogen hydride [Term] id: CHEBI:33694 name: biomacromolecule namespace: chebi_ontology def: "A macromolecule formed by a living organism." [] subset: 3_STAR synonym: "biomacromolecules" RELATED [ChEBI] synonym: "biopolymer" EXACT IUPAC_NAME [IUPAC] synonym: "Biopolymere" RELATED [ChEBI] synonym: "biopolymers" RELATED [ChEBI] is_a: CHEBI:33839 ! macromolecule is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:33695 name: information biomacromolecule namespace: chebi_ontology subset: 3_STAR synonym: "genetically encoded biomacromolecules" RELATED [ChEBI] synonym: "genetically encoded biopolymers" RELATED [ChEBI] synonym: "information biomacromolecules" RELATED [ChEBI] synonym: "information biopolymers" RELATED [ChEBI] synonym: "information macromolecule" RELATED [ChEBI] synonym: "information macromolecules" RELATED [ChEBI] is_a: CHEBI:33694 ! biomacromolecule [Term] id: CHEBI:33696 name: nucleic acid namespace: chebi_ontology def: "A macromolecule made up of nucleotide units and hydrolysable into certain pyrimidine or purine bases (usually adenine, cytosine, guanine, thymine, uracil), D-ribose or 2-deoxy-D-ribose and phosphoric acid." [] subset: 3_STAR synonym: "acide nucleique" RELATED [ChEBI] synonym: "acides nucleiques" RELATED [ChEBI] synonym: "acido nucleico" RELATED [ChEBI] synonym: "acidos nucleicos" RELATED [ChEBI] synonym: "NA" RELATED [ChEBI] synonym: "nucleic acids" EXACT IUPAC_NAME [IUPAC] synonym: "Nukleinsaeure" RELATED [ChEBI] synonym: "Nukleinsaeuren" RELATED [ChEBI] is_a: CHEBI:15986 ! polynucleotide relationship: has_part CHEBI:33791 ! canonical nucleoside residue relationship: has_part CHEBI:50297 ! canonical nucleotide residue [Term] id: CHEBI:33697 name: ribonucleic acid namespace: chebi_ontology def: "High molecular weight, linear polymers, composed of nucleotides containing ribose and linked by phosphodiester bonds; RNA is central to the synthesis of proteins." [] subset: 3_STAR synonym: "pentosenucleic acids" RELATED [ChemIDplus] synonym: "ribonucleic acid" EXACT [IUPAC] synonym: "ribonucleic acids" EXACT IUPAC_NAME [IUPAC] synonym: "ribonucleic acids" RELATED [ChEBI] synonym: "Ribonukleinsaeure" RELATED [ChEBI] synonym: "ribose nucleic acid" RELATED [ChEBI] synonym: "RNA" RELATED [UniProt] synonym: "RNA" RELATED [IUPAC] synonym: "RNS" RELATED [ChEBI] synonym: "yeast nucleic acid" RELATED [ChEBI] xref: CAS:63231-63-0 {source="ChemIDplus"} is_a: CHEBI:33696 ! nucleic acid relationship: has_part CHEBI:33792 ! canonical ribonucleoside residue relationship: has_part CHEBI:50299 ! canonical ribonucleotide residue [Term] id: CHEBI:33700 name: proteinogenic amino-acid residue namespace: chebi_ontology subset: 3_STAR synonym: "canonical amino-acid residue" RELATED [ChEBI] synonym: "canonical amino-acid residues" RELATED [ChEBI] synonym: "common amino acid residues" RELATED [ChEBI] synonym: "proteinogenic amino-acid residues" RELATED [ChEBI] synonym: "standard amino acid residues" RELATED [ChEBI] synonym: "standard amino-acid residues" RELATED [ChEBI] is_a: CHEBI:33710 ! alpha-amino-acid residue [Term] id: CHEBI:33702 name: polyatomic cation namespace: chebi_ontology def: "A cation consisting of more than one atom." [] subset: 3_STAR synonym: "polyatomic cations" RELATED [ChEBI] is_a: CHEBI:36358 ! polyatomic ion is_a: CHEBI:36916 ! cation [Term] id: CHEBI:33704 name: alpha-amino acid namespace: chebi_ontology alt_id: CHEBI:10208 alt_id: CHEBI:13779 alt_id: CHEBI:22442 alt_id: CHEBI:2642 def: "An amino acid in which the amino group is located on the carbon atom at the position alpha to the carboxy group." [] subset: 3_STAR synonym: "alpha-amino acid" EXACT IUPAC_NAME [IUPAC] synonym: "alpha-amino acids" RELATED [JCBN] synonym: "alpha-amino acids" RELATED [ChEBI] synonym: "alpha-amino carboxylic acids" RELATED [IUPAC] synonym: "Amino acid" RELATED [KEGG_COMPOUND] synonym: "Amino acids" RELATED [KEGG_COMPOUND] xref: KEGG:C00045 xref: KEGG:C05167 is_a: CHEBI:33709 ! amino acid relationship: is_conjugate_acid_of CHEBI:33558 ! alpha-amino-acid anion relationship: is_tautomer_of CHEBI:78608 ! alpha-amino acid zwitterion property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H4NO2R" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "74.05870" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "74.02420" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "NC([*])C(O)=O" xsd:string [Term] id: CHEBI:33708 name: amino-acid residue namespace: chebi_ontology def: "When two or more amino acids combine to form a peptide, the elements of water are removed, and what remains of each amino acid is called an amino-acid residue." [Dummy:dummy] subset: 3_STAR synonym: "amino acid residue" EXACT [] synonym: "amino acid residue" RELATED [ChEBI] synonym: "amino-acid residue" EXACT IUPAC_NAME [IUPAC] synonym: "amino-acid residues" RELATED [JCBN] synonym: "protein residue" NARROW [PRO:DAN] is_a: CHEBI:33247 ! organic group relationship: is_substituent_group_from CHEBI:33709 ! amino acid [Term] id: CHEBI:33709 name: amino acid namespace: chebi_ontology alt_id: CHEBI:13815 alt_id: CHEBI:22477 def: "A carboxylic acid containing one or more amino groups." [] subset: 3_STAR synonym: "amino acids" RELATED [ChEBI] synonym: "Aminocarbonsaeure" RELATED [ChEBI] synonym: "Aminokarbonsaeure" RELATED [ChEBI] synonym: "Aminosaeure" RELATED [ChEBI] xref: Wikipedia:Amino_acid is_a: CHEBI:33575 ! carboxylic acid is_a: CHEBI:50047 ! organic amino compound relationship: is_conjugate_acid_of CHEBI:37022 ! amino-acid anion [Term] id: CHEBI:33710 name: alpha-amino-acid residue namespace: chebi_ontology subset: 3_STAR synonym: "alpha-amino-acid residues" RELATED [ChEBI] is_a: CHEBI:33708 ! amino-acid residue relationship: is_substituent_group_from CHEBI:33704 ! alpha-amino acid [Term] id: CHEBI:33720 name: carbohydrate acid namespace: chebi_ontology subset: 3_STAR synonym: "carbohydrate acid" EXACT [ChEBI] synonym: "carbohydrate acids" RELATED [ChEBI] is_a: CHEBI:16646 ! carbohydrate is_a: CHEBI:33575 ! carboxylic acid relationship: is_conjugate_acid_of CHEBI:33721 ! carbohydrate acid anion [Term] id: CHEBI:33721 name: carbohydrate acid anion namespace: chebi_ontology subset: 3_STAR synonym: "carbohydrate acid anion" EXACT [ChEBI] synonym: "carbohydrate acid anions" RELATED [ChEBI] is_a: CHEBI:29067 ! carboxylic acid anion relationship: is_conjugate_base_of CHEBI:33720 ! carbohydrate acid [Term] id: CHEBI:33791 name: canonical nucleoside residue namespace: chebi_ontology subset: 3_STAR synonym: "canonical nucleoside residues" RELATED [ChEBI] synonym: "common nucleoside residues" RELATED [CBN] synonym: "nucleoside residue" RELATED [CBN] synonym: "standard nucleoside residues" RELATED [ChEBI] is_a: CHEBI:50320 ! nucleoside residue [Term] id: CHEBI:33792 name: canonical ribonucleoside residue namespace: chebi_ontology subset: 3_STAR synonym: "canonical ribonucleoside residues" RELATED [ChEBI] synonym: "common ribonucleoside residue" RELATED [CBN] synonym: "common ribonucleoside residues" RELATED [CBN] synonym: "N" RELATED [CBN] synonym: "Nuc" RELATED [CBN] synonym: "standard ribonucleoside residues" RELATED [ChEBI] is_a: CHEBI:33791 ! canonical nucleoside residue [Term] id: CHEBI:33793 name: canonical deoxyribonucleoside residue namespace: chebi_ontology subset: 3_STAR synonym: "canonical deoxyribonucleoside residues" RELATED [ChEBI] synonym: "common 2'-deoxyribonucleoside residue" RELATED [CBN] synonym: "common 2'-deoxyribonucleoside residues" RELATED [CBN] synonym: "dN" RELATED [CBN] synonym: "dNuc" RELATED [CBN] synonym: "standard deoxyribonucleoside residues" RELATED [ChEBI] is_a: CHEBI:33791 ! canonical nucleoside residue [Term] id: CHEBI:33822 name: organic hydroxy compound namespace: chebi_ontology alt_id: CHEBI:64710 def: "An organic compound having at least one hydroxy group attached to a carbon atom." [] subset: 3_STAR synonym: "hydroxy compounds" EXACT IUPAC_NAME [IUPAC] synonym: "organic alcohol" RELATED [ChEBI] synonym: "organic hydroxy compounds" RELATED [ChEBI] is_a: CHEBI:24651 ! hydroxides is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:33832 name: organic cyclic compound namespace: chebi_ontology def: "Any organic molecule that consists of atoms connected in the form of a ring." [] subset: 3_STAR synonym: "organic cyclic compounds" RELATED [ChEBI] is_a: CHEBI:33595 ! cyclic compound is_a: CHEBI:72695 ! organic molecule [Term] id: CHEBI:33833 name: heteroarene namespace: chebi_ontology def: "A heterocyclic compound formally derived from an arene by replacement of one or more methine (-C=) and/or vinylene (-CH=CH-) groups by trivalent or divalent heteroatoms, respectively, in such a way as to maintain the continuous pi-electron system characteristic of aromatic systems and a number of out-of-plane pi-electrons corresponding to the Hueckel rule (4n+2)." [] subset: 3_STAR synonym: "hetarenes" RELATED [IUPAC] synonym: "heteroarenes" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:24532 ! organic heterocyclic compound is_a: CHEBI:33659 ! organic aromatic compound [Term] id: CHEBI:33837 name: conjugated protein namespace: chebi_ontology def: "Conjugated protein is a protein that contains a non-peptide component, usually in stoichiometric proportion." [] subset: 3_STAR synonym: "complex protein" RELATED [COMe] synonym: "conjugated proteins" EXACT IUPAC_NAME [IUPAC] xref: COMe:PRX000001 is_a: CHEBI:36080 ! protein [Term] id: CHEBI:33839 name: macromolecule namespace: chebi_ontology def: "A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [] subset: 3_STAR synonym: "macromolecule" EXACT IUPAC_NAME [IUPAC] synonym: "macromolecules" RELATED [ChEBI] synonym: "polymer" RELATED [ChEBI] synonym: "polymer molecule" RELATED [IUPAC] synonym: "polymers" RELATED [ChEBI] xref: Wikipedia:Macromolecule is_a: CHEBI:36357 ! polyatomic entity [Term] id: CHEBI:33853 name: phenols namespace: chebi_ontology alt_id: CHEBI:13664 alt_id: CHEBI:13825 alt_id: CHEBI:25969 alt_id: CHEBI:2857 def: "Organic aromatic compounds having one or more hydroxy groups attached to a benzene or other arene ring." [] subset: 3_STAR synonym: "a phenol" RELATED [UniProt] synonym: "arenols" RELATED [IUPAC] synonym: "Aryl alcohol" RELATED [KEGG_COMPOUND] synonym: "phenols" EXACT IUPAC_NAME [IUPAC] xref: KEGG:C15584 xref: MetaCyc:Phenols xref: Wikipedia:Phenols is_a: CHEBI:33659 ! organic aromatic compound is_a: CHEBI:33822 ! organic hydroxy compound property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C6HOR5" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "89.072" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "89.00274" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "C1(=C(C(=C(C(=C1*)*)*)*)*)O" xsd:string [Term] id: CHEBI:33893 name: reagent namespace: chebi_ontology def: "A substance used in a chemical reaction to detect, measure, examine, or produce other substances." [] subset: 3_STAR synonym: "reactif" RELATED [IUPAC] synonym: "reactivo" RELATED [IUPAC] synonym: "reagent" EXACT IUPAC_NAME [IUPAC] synonym: "reagents" RELATED [ChEBI] is_a: CHEBI:33232 ! application [Term] id: CHEBI:33917 name: aldohexose namespace: chebi_ontology alt_id: CHEBI:2558 def: "A hexose with a (potential) aldehyde group at one end." [] subset: 3_STAR synonym: "aldohexose" EXACT [ChEBI] synonym: "aldohexoses" RELATED [ChEBI] is_a: CHEBI:15693 ! aldose is_a: CHEBI:18133 ! hexose [Term] id: CHEBI:33937 name: macronutrient namespace: chebi_ontology def: "Any nutrient required in large quantities by organisms throughout their life in order to orchestrate a range of physiological functions. Macronutrients are usually chemical elements (carbon, hydrogen, nitrogen, oxygen, phosphorus and sulfur) that humans consume in the largest quantities. Calcium, sodium, magnesium and potassium are sometimes included as macronutrients because they are required in relatively large quantities compared with other vitamins and minerals." [] subset: 3_STAR synonym: "macronutrients" RELATED [ChEBI] is_a: CHEBI:33284 ! nutrient [Term] id: CHEBI:350546 name: serotonin(1+) namespace: chebi_ontology def: "An ammonium ion that is the conjugate acid of serotonin; major species at pH 7.3." [] subset: 3_STAR synonym: "2-(5-hydroxy-1H-indol-3-yl)ethanaminium" EXACT IUPAC_NAME [IUPAC] synonym: "serotonin" RELATED [UniProt] synonym: "serotonin cation" RELATED [ChEBI] is_a: CHEBI:35274 ! ammonium ion derivative relationship: has_role CHEBI:77746 ! human metabolite relationship: is_conjugate_acid_of CHEBI:28790 ! serotonin property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C10H13N2O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2/p+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QZAYGJVTTNCVMB-UHFFFAOYSA-O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "177.22250" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "177.10224" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[NH3+]CCc1c[nH]c2ccc(O)cc12" xsd:string [Term] id: CHEBI:35106 name: nitrogen hydride namespace: chebi_ontology subset: 3_STAR synonym: "nitrogen hydrides" RELATED [ChEBI] is_a: CHEBI:35881 ! pnictogen hydride is_a: CHEBI:51143 ! nitrogen molecular entity [Term] id: CHEBI:35107 name: azane namespace: chebi_ontology def: "Saturated acyclic nitrogen hydrides having the general formula NnHn+2." [] subset: 3_STAR synonym: "azanes" RELATED [ChEBI] is_a: CHEBI:35106 ! nitrogen hydride [Term] id: CHEBI:35222 name: inhibitor namespace: chebi_ontology def: "A substance that diminishes the rate of a chemical reaction." [] subset: 3_STAR synonym: "inhibidor" RELATED [ChEBI] synonym: "inhibiteur" RELATED [ChEBI] synonym: "inhibitor" EXACT IUPAC_NAME [IUPAC] synonym: "inhibitors" RELATED [ChEBI] is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:35223 name: catalyst namespace: chebi_ontology def: "A substance that increases the rate of a reaction without modifying the overall standard Gibbs energy change in the reaction." [] subset: 3_STAR synonym: "catalizador" RELATED [ChEBI] synonym: "catalyseur" RELATED [ChEBI] synonym: "catalyst" EXACT IUPAC_NAME [IUPAC] synonym: "Katalysator" RELATED [ChEBI] is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:35238 name: amino acid zwitterion namespace: chebi_ontology def: "The zwitterionic form of an amino acid having a negatively charged carboxyl group and a positively charged amino group." [] subset: 3_STAR synonym: "amino acid zwitterion" EXACT [ChEBI] is_a: CHEBI:27369 ! zwitterion [Term] id: CHEBI:35267 name: quaternary ammonium ion namespace: chebi_ontology alt_id: CHEBI:26470 alt_id: CHEBI:8693 def: "A derivative of ammonium, NH4(+), in which all four of the hydrogens bonded to nitrogen have been replaced with univalent (usually organyl) groups." [] subset: 3_STAR synonym: "a quaternary ammonium" RELATED [UniProt] synonym: "Quaternary amine" RELATED [KEGG_COMPOUND] synonym: "quaternary ammonium ion" EXACT IUPAC_NAME [IUPAC] synonym: "quaternary ammonium ions" RELATED [ChEBI] xref: KEGG:C06703 is_a: CHEBI:25697 ! organic cation is_a: CHEBI:35274 ! ammonium ion derivative property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "NR4" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "14.00670" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "14.00307" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[*][N+]([*])([*])[*]" xsd:string [Term] id: CHEBI:35274 name: ammonium ion derivative namespace: chebi_ontology def: "A derivative of ammonium, NH4(+), in which one (or more) of the hydrogens bonded to the nitrogen have been replaced with univalent organyl groups. The substituting carbon of the organyl group must not itself be directly attached to a heteroatom (thereby excluding protonated amides, hemiaminals, etc)." [] subset: 3_STAR synonym: "ammonium ion derivatives" RELATED [ChEBI] synonym: "azanium ion derivative" RELATED [ChEBI] synonym: "azanium ion derivatives" RELATED [ChEBI] is_a: CHEBI:33702 ! polyatomic cation is_a: CHEBI:51143 ! nitrogen molecular entity relationship: has_parent_hydride CHEBI:28938 ! ammonium [Term] id: CHEBI:35287 name: acylcholine namespace: chebi_ontology alt_id: CHEBI:13245 alt_id: CHEBI:22227 alt_id: CHEBI:2463 def: "A choline ester formed from choline and a carboxylic acid." [] subset: 3_STAR synonym: "acylcholines" RELATED [ChEBI] synonym: "an acylcholine" RELATED [UniProt] xref: KEGG:C01777 is_a: CHEBI:35267 ! quaternary ammonium ion property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C6H13NO2R" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "131.17290" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "131.09463" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "C[N+](C)(C)CCOC([*])=O" xsd:string [Term] id: CHEBI:35341 name: steroid namespace: chebi_ontology alt_id: CHEBI:13687 alt_id: CHEBI:26768 alt_id: CHEBI:9263 def: "Any of naturally occurring compounds and synthetic analogues, based on the cyclopenta[a]phenanthrene carbon skeleton, partially or completely hydrogenated; there are usually methyl groups at C-10 and C-13, and often an alkyl group at C-17. By extension, one or more bond scissions, ring expansions and/or ring contractions of the skeleton may have occurred. Natural steroids are derived biogenetically from squalene which is a triterpene." [] subset: 3_STAR synonym: "a steroid" RELATED [UniProt] synonym: "Steroid" EXACT [KEGG_COMPOUND] synonym: "steroids" EXACT IUPAC_NAME [IUPAC] xref: KEGG:C00377 xref: MetaCyc:Steroids is_a: CHEBI:18059 ! lipid is_a: CHEBI:51958 ! organic polycyclic compound property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C19H31R" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "259.450" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "259.24258" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "C12C(C3C(C(CC3)*)(C)CC1)CCC4C2(CCCC4)C" xsd:string [Term] id: CHEBI:35350 name: hydroxy steroid namespace: chebi_ontology alt_id: CHEBI:24748 alt_id: CHEBI:5814 subset: 3_STAR synonym: "hydroxy steroids" RELATED [ChEBI] synonym: "Hydroxysteroid" RELATED [KEGG_COMPOUND] synonym: "hydroxysteroids" RELATED [ChEBI] xref: KEGG:C02159 is_a: CHEBI:33822 ! organic hydroxy compound is_a: CHEBI:35341 ! steroid [Term] id: CHEBI:35352 name: organonitrogen compound namespace: chebi_ontology def: "Any heteroorganic entity containing at least one carbon-nitrogen bond." [] subset: 3_STAR synonym: "organonitrogen compounds" EXACT IUPAC_NAME [IUPAC] synonym: "organonitrogens" RELATED [ChEBI] is_a: CHEBI:33285 ! heteroorganic entity is_a: CHEBI:51143 ! nitrogen molecular entity [Term] id: CHEBI:35381 name: monosaccharide namespace: chebi_ontology alt_id: CHEBI:25407 alt_id: CHEBI:6984 def: "Parent monosaccharides are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H-[CHOH]n-C(=O)[CHOH]m-H with three or more carbon atoms. The generic term 'monosaccharide' (as opposed to oligosaccharide or polysaccharide) denotes a single unit, without glycosidic connection to other such units. It includes aldoses, dialdoses, aldoketoses, ketoses and diketoses, as well as deoxy sugars, provided that the parent compound has a (potential) carbonyl group." [] subset: 3_STAR synonym: "monosacarido" RELATED [ChEBI] synonym: "monosacaridos" RELATED [IUPAC] synonym: "Monosaccharid" RELATED [ChEBI] synonym: "Monosaccharide" EXACT [KEGG_COMPOUND] synonym: "monosaccharides" EXACT IUPAC_NAME [IUPAC] synonym: "Monosacharid" RELATED [ChEBI] xref: KEGG:C06698 is_a: CHEBI:16646 ! carbohydrate [Term] id: CHEBI:35406 name: oxoanion namespace: chebi_ontology alt_id: CHEBI:33274 alt_id: CHEBI:33436 def: "An oxoanion is an anion derived from an oxoacid by loss of hydron(s) bound to oxygen." [] subset: 3_STAR synonym: "oxoacid anions" RELATED [ChEBI] synonym: "oxoanion" EXACT [ChEBI] synonym: "oxoanions" RELATED [ChEBI] is_a: CHEBI:25741 ! oxide is_a: CHEBI:33273 ! polyatomic anion [Term] id: CHEBI:35472 name: anti-inflammatory drug namespace: chebi_ontology def: "A substance that reduces or suppresses inflammation." [] subset: 3_STAR synonym: "anti-inflammatory drugs" RELATED [ChEBI] synonym: "antiinflammatory agent" RELATED [ChEBI] synonym: "antiinflammatory drug" RELATED [ChEBI] synonym: "antiinflammatory drugs" RELATED [ChEBI] is_a: CHEBI:23888 ! drug is_a: CHEBI:67079 ! anti-inflammatory agent [Term] id: CHEBI:35479 name: alkali metal salt namespace: chebi_ontology subset: 3_STAR synonym: "alkali metal salts" RELATED [ChEBI] is_a: CHEBI:24866 ! salt is_a: CHEBI:33296 ! alkali metal molecular entity [Term] id: CHEBI:35507 name: natural product fundamental parent namespace: chebi_ontology subset: 3_STAR synonym: "natural product fundamental parents" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:33245 ! organic fundamental parent [Term] id: CHEBI:35508 name: steroid fundamental parent namespace: chebi_ontology subset: 3_STAR synonym: "steroid fundamental parents" RELATED [ChEBI] is_a: CHEBI:35341 ! steroid is_a: CHEBI:35507 ! natural product fundamental parent [Term] id: CHEBI:35519 name: cholane namespace: chebi_ontology subset: 3_STAR synonym: "cholane" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:35508 ! steroid fundamental parent property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C24H42" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C24H42/c1-5-8-17(2)20-12-13-21-19-11-10-18-9-6-7-15-23(18,3)22(19)14-16-24(20,21)4/h17-22H,5-16H2,1-4H3/t17-,18?,19+,20-,21+,22+,23+,24-/m1/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QSHQKIURKJITMZ-BRPMRXRMSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "330.59028" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "330.32865" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][C@@]1(CC[C@@]2([H])[C@]3([H])CCC4CCCC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCC" xsd:string [Term] id: CHEBI:35524 name: sympathomimetic agent namespace: chebi_ontology def: "A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters." [] subset: 3_STAR synonym: "sympathomimetic" RELATED [ChEBI] synonym: "sympathomimetics" RELATED [ChEBI] is_a: CHEBI:37962 ! adrenergic agent [Term] id: CHEBI:35554 name: cardiovascular drug namespace: chebi_ontology def: "A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume." [] subset: 3_STAR synonym: "cardiovascular agent" RELATED [ChEBI] synonym: "cardiovascular drugs" RELATED [ChEBI] is_a: CHEBI:23888 ! drug [Term] id: CHEBI:35569 name: alpha-adrenergic agonist namespace: chebi_ontology def: "An agent that selectively binds to and activates alpha-adrenergic receptors." [] subset: 3_STAR synonym: "alpha-adrenergic agonists" RELATED [ChEBI] synonym: "alpha-adrenergic receptor agonist" RELATED [ChEBI] synonym: "alpha-adrenoceptor agonists" RELATED [IUPHAR] is_a: CHEBI:37886 ! adrenergic agonist is_a: CHEBI:48539 ! alpha-adrenergic drug [Term] id: CHEBI:35604 name: carbon oxoanion namespace: chebi_ontology def: "A negative ion consisting solely of carbon and oxygen atoms, and therefore having the general formula CxOy(n-) for some integers x, y and n." [] subset: 3_STAR synonym: "carbon oxoanion" EXACT [ChEBI] synonym: "carbon oxoanions" RELATED [ChEBI] synonym: "oxocarbon anion" RELATED [ChEBI] synonym: "oxocarbon anions" RELATED [ChEBI] is_a: CHEBI:25696 ! organic anion is_a: CHEBI:35406 ! oxoanion is_a: CHEBI:36963 ! organooxygen compound [Term] id: CHEBI:35605 name: carbon oxoacid namespace: chebi_ontology subset: 3_STAR synonym: "carbon oxoacids" RELATED [ChEBI] synonym: "oxoacids of carbon" RELATED [ChEBI] is_a: CHEBI:24833 ! oxoacid is_a: CHEBI:36963 ! organooxygen compound [Term] id: CHEBI:35620 name: vasodilator agent namespace: chebi_ontology def: "A drug used to cause dilation of the blood vessels." [] subset: 3_STAR synonym: "vasodilator" RELATED [ChEBI] synonym: "vasodilator agents" RELATED [ChEBI] is_a: CHEBI:35554 ! cardiovascular drug [Term] id: CHEBI:35692 name: dicarboxylic acid namespace: chebi_ontology alt_id: CHEBI:23692 alt_id: CHEBI:36172 alt_id: CHEBI:4501 def: "Any carboxylic acid containing two carboxy groups." [] subset: 3_STAR synonym: "Dicarboxylic acid" EXACT [KEGG_COMPOUND] synonym: "dicarboxylic acids" RELATED [ChEBI] xref: KEGG:C02028 is_a: CHEBI:131927 ! dicarboxylic acids and O-substituted derivatives is_a: CHEBI:33575 ! carboxylic acid relationship: is_conjugate_acid_of CHEBI:35693 ! dicarboxylic acid anion [Term] id: CHEBI:35693 name: dicarboxylic acid anion namespace: chebi_ontology subset: 3_STAR synonym: "dicarboxylic acid anion" EXACT [ChEBI] synonym: "dicarboxylic acid anions" RELATED [ChEBI] is_a: CHEBI:29067 ! carboxylic acid anion relationship: is_conjugate_base_of CHEBI:35692 ! dicarboxylic acid [Term] id: CHEBI:35701 name: ester namespace: chebi_ontology alt_id: CHEBI:23960 alt_id: CHEBI:4859 def: "A compound formally derived from an oxoacid RkE(=O)l(OH)m (l > 0) and an alcohol, phenol, heteroarenol, or enol by linking with formal loss of water from an acidic hydroxy group of the former and a hydroxy group of the latter." [] subset: 3_STAR synonym: "Ester" EXACT [KEGG_COMPOUND] synonym: "esters" RELATED [ChEBI] xref: KEGG:C00287 xref: Wikipedia:Ester is_a: CHEBI:36963 ! organooxygen compound [Term] id: CHEBI:35722 name: sulfated glycosaminoglycan namespace: chebi_ontology subset: 3_STAR synonym: "glycosaminoglycan sulfate" RELATED [ChEBI] synonym: "glycosaminoglycan sulfates" RELATED [ChEBI] synonym: "sulfated glycosaminoglycans" RELATED [ChEBI] is_a: CHEBI:18085 ! glycosaminoglycan is_a: CHEBI:35724 ! carbohydrate sulfate [Term] id: CHEBI:35724 name: carbohydrate sulfate namespace: chebi_ontology subset: 3_STAR synonym: "carbohydrate sulfates" RELATED [ChEBI] synonym: "carbohydrate sulphates" RELATED [ChEBI] is_a: CHEBI:25704 ! organic sulfate is_a: CHEBI:26819 ! sulfuric ester is_a: CHEBI:63299 ! carbohydrate derivative [Term] id: CHEBI:35757 name: monocarboxylic acid anion namespace: chebi_ontology alt_id: CHEBI:13657 alt_id: CHEBI:25382 alt_id: CHEBI:3407 def: "A carboxylic acid anion formed when the carboxy group of a monocarboxylic acid is deprotonated." [] subset: 3_STAR synonym: "a monocarboxylate" RELATED [UniProt] synonym: "Carboxylate" RELATED [KEGG_COMPOUND] synonym: "Monocarboxylate" RELATED [KEGG_COMPOUND] synonym: "monocarboxylates" RELATED [ChEBI] synonym: "monocarboxylic acid anions" RELATED [ChEBI] xref: KEGG:C00060 is_a: CHEBI:29067 ! carboxylic acid anion relationship: is_conjugate_base_of CHEBI:25384 ! monocarboxylic acid property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CO2R" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "44.01000" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "43.98983" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]C([*])=O" xsd:string [Term] id: CHEBI:35780 name: phosphate ion namespace: chebi_ontology def: "A phosphorus oxoanion that is the conjugate base of phosphoric acid." [] subset: 3_STAR synonym: "phosphate" RELATED [ChEBI] synonym: "phosphate ions" RELATED [ChEBI] synonym: "Pi" RELATED [ChEBI] is_a: CHEBI:33461 ! phosphorus oxoanion relationship: has_role CHEBI:77746 ! human metabolite relationship: is_conjugate_base_of CHEBI:26078 ! phosphoric acid [Term] id: CHEBI:35881 name: pnictogen hydride namespace: chebi_ontology subset: 3_STAR synonym: "pnictogen hydride" EXACT [ChEBI] synonym: "pnictogen hydrides" RELATED [ChEBI] is_a: CHEBI:33242 ! inorganic hydride is_a: CHEBI:33302 ! pnictogen molecular entity [Term] id: CHEBI:35942 name: neurotransmitter agent namespace: chebi_ontology def: "A substance used for its pharmacological action on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function." [] subset: 3_STAR synonym: "neurotransmitter agents" RELATED [ChEBI] is_a: CHEBI:23888 ! drug is_a: CHEBI:52210 ! pharmacological role [Term] id: CHEBI:36078 name: cholanoid namespace: chebi_ontology alt_id: CHEBI:22867 alt_id: CHEBI:50419 subset: 3_STAR synonym: "bile acids and derivatives" RELATED [LIPID_MAPS] synonym: "cholanoids" RELATED [ChEBI] xref: LIPID_MAPS_class:LMST04 {source="LIPID MAPS"} is_a: CHEBI:35341 ! steroid relationship: has_parent_hydride CHEBI:35519 ! cholane [Term] id: CHEBI:36080 name: protein namespace: chebi_ontology alt_id: CHEBI:13677 alt_id: CHEBI:14911 def: "A biological macromolecule minimally consisting of one polypeptide chain synthesized at the ribosome." [] subset: 3_STAR synonym: "proteins" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:33695 ! information biomacromolecule relationship: has_part CHEBI:16541 ! protein polypeptide chain [Term] id: CHEBI:36235 name: bile acid anion namespace: chebi_ontology subset: 3_STAR synonym: "bile acid anions" RELATED [ChEBI] is_a: CHEBI:35757 ! monocarboxylic acid anion is_a: CHEBI:50160 ! steroid acid anion [Term] id: CHEBI:36237 name: cholanic acid namespace: chebi_ontology def: "A steroid acid that consists of cholane having a carboxy group in place of the methyl group at position 24." [] subset: 3_STAR synonym: "cholan-24-oic acid" EXACT IUPAC_NAME [IUPAC] xref: CAS:25312-65-6 {source="ChemIDplus"} xref: Patent:JP2008069152 xref: Reaxys:13246008 {source="Reaxys"} is_a: CHEBI:36278 ! cholanic acids property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C24H40O2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C24H40O2/c1-16(7-12-22(25)26)19-10-11-20-18-9-8-17-6-4-5-14-23(17,2)21(18)13-15-24(19,20)3/h16-21H,4-15H2,1-3H3,(H,25,26)/t16-,17?,18+,19-,20+,21+,23+,24-/m1/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "RPKLZQLYODPWTM-KBMWBBLPSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "360.57320" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "360.30283" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][C@@]1(CC[C@@]2([H])[C@]3([H])CCC4CCCC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCC(O)=O" xsd:string [Term] id: CHEBI:36238 name: 5beta-cholanic acid namespace: chebi_ontology subset: 3_STAR synonym: "(5beta)-cholan-24-oic acid" RELATED [ChemIDplus] synonym: "(5beta,17beta)-gamma-methylandrostane-17-butanoic acid" RELATED [ChemIDplus] synonym: "5beta-cholan-24-oic acid" EXACT IUPAC_NAME [IUPAC] synonym: "5beta-cholanic acid" EXACT [ChemIDplus] synonym: "5beta-cholanoic acid" RELATED [ChemIDplus] synonym: "ursocholanic acid" RELATED [ChemIDplus] xref: Beilstein:3214794 {source="Beilstein"} xref: CAS:546-18-9 {source="ChemIDplus"} xref: LIPID_MAPS_instance:LMST04010441 {source="LIPID MAPS"} is_a: CHEBI:36237 ! cholanic acid is_a: CHEBI:36248 ! 5beta-cholanic acids property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C24H40O2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C24H40O2/c1-16(7-12-22(25)26)19-10-11-20-18-9-8-17-6-4-5-14-23(17,2)21(18)13-15-24(19,20)3/h16-21H,4-15H2,1-3H3,(H,25,26)/t16-,17+,18+,19-,20+,21+,23+,24-/m1/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "RPKLZQLYODPWTM-LVVAJZGHSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "360.57320" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "360.30283" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][C@@]12CCCC[C@]1(C)[C@@]1([H])CC[C@]3(C)[C@]([H])(CC[C@@]3([H])[C@]1([H])CC2)[C@H](C)CCC(O)=O" xsd:string [Term] id: CHEBI:36248 name: 5beta-cholanic acids namespace: chebi_ontology def: "Members of the class of cholanic acids based on a 5beta-cholane skeleton." [] subset: 3_STAR is_a: CHEBI:136889 ! 5beta steroid is_a: CHEBI:36278 ! cholanic acids relationship: has_parent_hydride CHEBI:20664 ! 5beta-cholane [Term] id: CHEBI:36277 name: bile acid salt namespace: chebi_ontology def: "A salt of a bile acid." [] subset: 3_STAR synonym: "bile acid salts" RELATED [ChEBI] is_a: CHEBI:24868 ! organic salt is_a: CHEBI:36078 ! cholanoid [Term] id: CHEBI:36278 name: cholanic acids namespace: chebi_ontology alt_id: CHEBI:23166 alt_id: CHEBI:23211 subset: 1_STAR is_a: CHEBI:36078 ! cholanoid is_a: CHEBI:47891 ! steroid acid [Term] id: CHEBI:36338 name: lepton namespace: chebi_ontology def: "Lepton is a fermion that does not experience the strong force (strong interaction). The term is derived from the Greek lambdaepsilonpitauomicronsigma (small, thin)." [] subset: 3_STAR synonym: "leptons" RELATED [ChEBI] is_a: CHEBI:33233 ! fundamental particle is_a: CHEBI:36340 ! fermion [Term] id: CHEBI:36339 name: baryon namespace: chebi_ontology def: "Baryon is a fermion that does experience the strong force (strong interaction). The term is derived from the Greek betaalpharhoupsilonsigma (heavy)." [] subset: 3_STAR synonym: "baryons" RELATED [ChEBI] is_a: CHEBI:36340 ! fermion is_a: CHEBI:36344 ! hadron [Term] id: CHEBI:36340 name: fermion namespace: chebi_ontology def: "Particle of half-integer spin quantum number following Fermi-Dirac statistics. Fermions are named after Enrico Fermi." [] subset: 3_STAR synonym: "fermion" EXACT IUPAC_NAME [IUPAC] synonym: "fermions" RELATED [ChEBI] is_a: CHEBI:36342 ! subatomic particle [Term] id: CHEBI:36341 name: boson namespace: chebi_ontology def: "Particle of integer spin quantum number following Bose-Einstein statistics. Bosons are named after Satyendra Nath Bose." [] subset: 3_STAR synonym: "boson" EXACT IUPAC_NAME [IUPAC] synonym: "bosons" RELATED [ChEBI] is_a: CHEBI:36342 ! subatomic particle [Term] id: CHEBI:36342 name: subatomic particle namespace: chebi_ontology def: "A particle smaller than an atom." [] subset: 3_STAR synonym: "subatomic particles" RELATED [ChEBI] xref: Wikipedia:Subatomic_particle [Term] id: CHEBI:36343 name: composite particle namespace: chebi_ontology def: "A subatomic particle known to have substructure (i.e. consisting of smaller particles)." [] subset: 3_STAR synonym: "composite particles" RELATED [ChEBI] is_a: CHEBI:36342 ! subatomic particle [Term] id: CHEBI:36344 name: hadron namespace: chebi_ontology def: "Hadron is a subatomic particle which experiences the strong force." [] subset: 3_STAR synonym: "hadrons" RELATED [ChEBI] is_a: CHEBI:36343 ! composite particle [Term] id: CHEBI:36347 name: nuclear particle namespace: chebi_ontology def: "A nucleus or any of its constituents in any of their energy states." [] subset: 3_STAR synonym: "nuclear particle" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:36342 ! subatomic particle [Term] id: CHEBI:36357 name: polyatomic entity namespace: chebi_ontology def: "Any molecular entity consisting of more than one atom." [] subset: 3_STAR synonym: "polyatomic entities" RELATED [ChEBI] is_a: CHEBI:23367 ! molecular entity relationship: has_part CHEBI:24433 ! group [Term] id: CHEBI:36358 name: polyatomic ion namespace: chebi_ontology def: "An ion consisting of more than one atom." [] subset: 3_STAR synonym: "polyatomic ions" RELATED [ChEBI] is_a: CHEBI:24870 ! ion is_a: CHEBI:36357 ! polyatomic entity [Term] id: CHEBI:36359 name: phosphorus oxoacid derivative namespace: chebi_ontology subset: 3_STAR synonym: "phosphorus oxoacid derivative" EXACT [ChEBI] is_a: CHEBI:33241 ! oxoacid derivative is_a: CHEBI:36360 ! phosphorus oxoacids and derivatives relationship: has_functional_parent CHEBI:33457 ! phosphorus oxoacid [Term] id: CHEBI:36360 name: phosphorus oxoacids and derivatives namespace: chebi_ontology subset: 1_STAR is_a: CHEBI:26082 ! phosphorus molecular entity [Term] id: CHEBI:36586 name: carbonyl compound namespace: chebi_ontology def: "Any compound containing the carbonyl group, C=O. The term is commonly used in the restricted sense of aldehydes and ketones, although it actually includes carboxylic acids and derivatives." [] subset: 3_STAR synonym: "carbonyl compounds" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:36587 ! organic oxo compound is_a: CHEBI:36963 ! organooxygen compound relationship: has_part CHEBI:23019 ! carbonyl group [Term] id: CHEBI:36587 name: organic oxo compound namespace: chebi_ontology def: "Organic compounds containing an oxygen atom, =O, doubly bonded to carbon or another element." [] subset: 3_STAR synonym: "organic oxo compounds" RELATED [ChEBI] synonym: "oxo compounds" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:72695 ! organic molecule relationship: has_part CHEBI:46629 ! oxo group [Term] id: CHEBI:36735 name: biladienes namespace: chebi_ontology def: "Compounds based on a biladiene skeleton." [] subset: 3_STAR is_a: CHEBI:25046 ! linear tetrapyrrole [Term] id: CHEBI:36902 name: chalcogen hydride namespace: chebi_ontology subset: 3_STAR synonym: "chalcogen hydride" EXACT [ChEBI] synonym: "chalcogen hydrides" RELATED [ChEBI] is_a: CHEBI:33242 ! inorganic hydride is_a: CHEBI:33304 ! chalcogen molecular entity [Term] id: CHEBI:36914 name: inorganic ion namespace: chebi_ontology subset: 3_STAR synonym: "inorganic ions" RELATED [ChEBI] is_a: CHEBI:24835 ! inorganic molecular entity is_a: CHEBI:24870 ! ion [Term] id: CHEBI:36915 name: inorganic cation namespace: chebi_ontology subset: 3_STAR synonym: "inorganic cations" RELATED [ChEBI] is_a: CHEBI:36914 ! inorganic ion is_a: CHEBI:36916 ! cation [Term] id: CHEBI:36916 name: cation namespace: chebi_ontology alt_id: CHEBI:23058 alt_id: CHEBI:3473 def: "A monoatomic or polyatomic species having one or more elementary charges of the proton." [] subset: 3_STAR synonym: "Cation" EXACT [KEGG_COMPOUND] synonym: "cation" EXACT IUPAC_NAME [IUPAC] synonym: "cation" EXACT [ChEBI] synonym: "cationes" RELATED [ChEBI] synonym: "cations" RELATED [ChEBI] synonym: "Kation" RELATED [ChEBI] synonym: "Kationen" RELATED [ChEBI] xref: KEGG:C01373 is_a: CHEBI:24870 ! ion [Term] id: CHEBI:36961 name: chalcocarbonic acid namespace: chebi_ontology subset: 3_STAR synonym: "chalcocarbonic acid" EXACT [ChEBI] synonym: "chalcocarbonic acids" EXACT IUPAC_NAME [IUPAC] synonym: "chalcocarbonic acids" RELATED [ChEBI] is_a: CHEBI:36962 ! organochalcogen compound [Term] id: CHEBI:36962 name: organochalcogen compound namespace: chebi_ontology def: "An organochalcogen compound is a compound containing at least one carbon-chalcogen bond." [] subset: 3_STAR synonym: "organochalcogen compound" EXACT [ChEBI] synonym: "organochalcogen compounds" RELATED [ChEBI] is_a: CHEBI:33285 ! heteroorganic entity is_a: CHEBI:33304 ! chalcogen molecular entity [Term] id: CHEBI:36963 name: organooxygen compound namespace: chebi_ontology def: "An organochalcogen compound containing at least one carbon-oxygen bond." [] subset: 3_STAR synonym: "organooxygen compound" EXACT [ChEBI] synonym: "organooxygen compounds" RELATED [ChEBI] xref: PMID:17586126 {source="Europe PMC"} is_a: CHEBI:25806 ! oxygen molecular entity is_a: CHEBI:36962 ! organochalcogen compound [Term] id: CHEBI:37022 name: amino-acid anion namespace: chebi_ontology subset: 3_STAR synonym: "amino acid anions" RELATED [ChEBI] synonym: "amino-acid anion" EXACT [ChEBI] synonym: "amino-acid anions" RELATED [ChEBI] is_a: CHEBI:29067 ! carboxylic acid anion is_a: CHEBI:35352 ! organonitrogen compound relationship: is_conjugate_base_of CHEBI:33709 ! amino acid [Term] id: CHEBI:37163 name: glucan namespace: chebi_ontology alt_id: CHEBI:24255 alt_id: CHEBI:5392 def: "A polysaccharide composed of glucose residues." [] subset: 3_STAR synonym: "Glucan" EXACT [KEGG_COMPOUND] synonym: "glucan" EXACT IUPAC_NAME [IUPAC] synonym: "glucans" RELATED [ChEBI] xref: CAS:9037-91-6 {source="ChemIDplus"} xref: KEGG:C01379 is_a: CHEBI:37164 ! homopolysaccharide property_value: http://purl.obolibrary.org/obo/chebi/formula "C12H22O11(C6H10O5)n" xsd:string [Term] id: CHEBI:37164 name: homopolysaccharide namespace: chebi_ontology def: "Glycans composed of a single type of monosaccharide residue. They are named by replacing the ending '-ose' of the sugar by '-an'." [] subset: 3_STAR synonym: "homoglycan" RELATED [IUPAC] synonym: "homopolysaccharide" EXACT IUPAC_NAME [IUPAC] synonym: "homopolysaccharides" RELATED [ChEBI] is_a: CHEBI:18154 ! polysaccharide [Term] id: CHEBI:37175 name: organic hydride namespace: chebi_ontology subset: 3_STAR synonym: "organic hydrides" RELATED [ChEBI] is_a: CHEBI:33692 ! hydrides [Term] id: CHEBI:37176 name: mononuclear parent hydride namespace: chebi_ontology subset: 3_STAR synonym: "mononuclear hydride" RELATED [ChEBI] synonym: "mononuclear hydrides" RELATED [IUPAC] synonym: "mononuclear parent hydrides" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:33692 ! hydrides [Term] id: CHEBI:37246 name: elemental sodium namespace: chebi_ontology subset: 3_STAR is_a: CHEBI:26712 ! sodium molecular entity [Term] id: CHEBI:37395 name: mucopolysaccharide namespace: chebi_ontology alt_id: CHEBI:25425 alt_id: CHEBI:7011 def: "Any of the group of polysaccharides composed of alternating units from uronic acids and glycosamines, and commonly partially esterified with sulfuric acid." [] subset: 3_STAR synonym: "mucopolisacarido" RELATED [ChEBI] synonym: "mucopolisacaridos" RELATED [IUPAC] synonym: "Mucopolysaccharid" RELATED [ChEBI] synonym: "Mucopolysaccharide" EXACT [KEGG_COMPOUND] synonym: "mucopolysaccharides" EXACT IUPAC_NAME [IUPAC] synonym: "Mukopolysaccharid" RELATED [ChEBI] xref: KEGG:C05114 is_a: CHEBI:18085 ! glycosaminoglycan [Term] id: CHEBI:37527 name: acid namespace: chebi_ontology alt_id: CHEBI:13800 alt_id: CHEBI:13801 alt_id: CHEBI:22209 alt_id: CHEBI:2426 def: "An acid is a molecular entity capable of donating a hydron (Bronsted acid) or capable of forming a covalent bond with an electron pair (Lewis acid)." [] subset: 3_STAR synonym: "Acid" EXACT [KEGG_COMPOUND] synonym: "acid" EXACT IUPAC_NAME [IUPAC] synonym: "acide" RELATED [IUPAC] synonym: "acido" RELATED [ChEBI] synonym: "acids" RELATED [ChEBI] synonym: "Saeure" RELATED [ChEBI] synonym: "Saeuren" RELATED [ChEBI] xref: KEGG:C00174 is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:37577 name: heteroatomic molecular entity namespace: chebi_ontology def: "A molecular entity consisting of two or more chemical elements." [] subset: 3_STAR synonym: "chemical compound" RELATED [ChEBI] synonym: "heteroatomic molecular entities" RELATED [ChEBI] is_a: CHEBI:36357 ! polyatomic entity [Term] id: CHEBI:37622 name: carboxamide namespace: chebi_ontology alt_id: CHEBI:35354 alt_id: CHEBI:35355 def: "An amide of a carboxylic acid, having the structure RC(=O)NR2. The term is used as a suffix in systematic name formation to denote the -C(=O)NH2 group including its carbon atom." [] subset: 3_STAR synonym: "carboxamides" EXACT IUPAC_NAME [IUPAC] synonym: "carboxamides" RELATED [ChEBI] synonym: "primary carboxamide" RELATED [ChEBI] is_a: CHEBI:33256 ! primary amide is_a: CHEBI:35352 ! organonitrogen compound is_a: CHEBI:36963 ! organooxygen compound relationship: has_part CHEBI:23004 ! carbamoyl group property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CNOR3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "42.01680" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "41.99799" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[*]C(=O)N([*])[*]" xsd:string [Term] id: CHEBI:37826 name: sulfuric acid derivative namespace: chebi_ontology subset: 3_STAR synonym: "sulfuric acid derivative" EXACT [ChEBI] synonym: "sulfuric acid derivatives" RELATED [ChEBI] is_a: CHEBI:33424 ! sulfur oxoacid derivative relationship: has_functional_parent CHEBI:26836 ! sulfuric acid [Term] id: CHEBI:37838 name: carboacyl group namespace: chebi_ontology def: "A carboacyl group is a group formed by loss of at least one OH from the carboxy group of a carboxylic acid." [] subset: 3_STAR synonym: "carboacyl groups" EXACT IUPAC_NAME [IUPAC] synonym: "carboxylic acyl group" EXACT IUPAC_NAME [IUPAC] synonym: "carboxylic acyl groups" RELATED [IUPAC] is_a: CHEBI:22221 ! acyl group relationship: is_substituent_group_from CHEBI:33575 ! carboxylic acid [Term] id: CHEBI:37886 name: adrenergic agonist namespace: chebi_ontology def: "An agent that selectively binds to and activates adrenergic receptors." [] subset: 3_STAR synonym: "adrenergic agonists" RELATED [ChEBI] synonym: "adrenergic receptor agonist" RELATED [ChEBI] synonym: "adrenoceptor agonists" RELATED [IUPHAR] synonym: "adrenomimetic" RELATED [ChEBI] synonym: "adrenomimetics" RELATED [ChEBI] is_a: CHEBI:37962 ! adrenergic agent [Term] id: CHEBI:37962 name: adrenergic agent namespace: chebi_ontology def: "Any agent that acts on an adrenergic receptor or affects the life cycle of an adrenergic transmitter." [] subset: 3_STAR synonym: "adrenergic agents" RELATED [ChEBI] synonym: "adrenergic drug" RELATED [ChEBI] synonym: "adrenergic drugs" RELATED [ChEBI] synonym: "adrenergic neuron agents" RELATED [ChEBI] synonym: "adrenergics" RELATED [ChEBI] is_a: CHEBI:35942 ! neurotransmitter agent [Term] id: CHEBI:38077 name: polypyrrole namespace: chebi_ontology def: "A compound composed of two or more pyrrole units." [] subset: 3_STAR synonym: "poly(pyrrole)s" RELATED [ChEBI] synonym: "polypyrroles" RELATED [ChEBI] synonym: "PPys" RELATED [ChEBI] xref: Beilstein:8538310 {source="Beilstein"} is_a: CHEBI:38101 ! organonitrogen heterocyclic compound [Term] id: CHEBI:38101 name: organonitrogen heterocyclic compound namespace: chebi_ontology def: "Any organonitrogen compound containing a cyclic component with nitrogen and at least one other element as ring member atoms." [] subset: 3_STAR synonym: "heterocyclic organonitrogen compounds" RELATED [ChEBI] synonym: "organonitrogen heterocyclic compounds" RELATED [ChEBI] is_a: CHEBI:24532 ! organic heterocyclic compound is_a: CHEBI:35352 ! organonitrogen compound [Term] id: CHEBI:38166 name: organic heteropolycyclic compound namespace: chebi_ontology alt_id: CHEBI:25429 alt_id: CHEBI:38075 subset: 3_STAR synonym: "organic heteropolycyclic compounds" RELATED [ChEBI] is_a: CHEBI:24532 ! organic heterocyclic compound is_a: CHEBI:33671 ! heteropolycyclic compound [Term] id: CHEBI:38180 name: polycyclic heteroarene namespace: chebi_ontology subset: 3_STAR synonym: "polycyclic heteroarenes" RELATED [ChEBI] is_a: CHEBI:33833 ! heteroarene [Term] id: CHEBI:38323 name: cholinergic drug namespace: chebi_ontology def: "Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons." [] subset: 3_STAR synonym: "cholinergic agent" RELATED [ChEBI] synonym: "cholinergic drugs" RELATED [ChEBI] synonym: "cholinomimetic" RELATED [ChEBI] is_a: CHEBI:35942 ! neurotransmitter agent [Term] id: CHEBI:38324 name: cholinergic agonist namespace: chebi_ontology def: "Any drug that binds to and activates cholinergic receptors." [] subset: 3_STAR synonym: "acetylcholine agonist" RELATED [ChEBI] synonym: "acetylcholine agonists" RELATED [ChEBI] synonym: "acetylcholine receptor agonist" RELATED [IUPHAR] synonym: "cholinergic agonists" RELATED [ChEBI] synonym: "cholinomimetic" RELATED [ChEBI] synonym: "cholinomimetics" RELATED [ChEBI] is_a: CHEBI:38323 ! cholinergic drug [Term] id: CHEBI:38325 name: muscarinic agonist namespace: chebi_ontology def: "Any drug that binds to and activates a muscarinic cholinergic receptor." [] subset: 3_STAR synonym: "muscarinic acetylcholine receptor agonist" RELATED [ChEBI] synonym: "muscarinic agonists" RELATED [ChEBI] synonym: "muscarinic cholinergic agonist" RELATED [ChEBI] synonym: "muscarinic cholinergic agonists" RELATED [ChEBI] is_a: CHEBI:38324 ! cholinergic agonist [Term] id: CHEBI:38631 name: aminoalkylindole namespace: chebi_ontology alt_id: CHEBI:22503 alt_id: CHEBI:24792 subset: 3_STAR synonym: "aminoalkylindoles" RELATED [ChEBI] is_a: CHEBI:24828 ! indoles [Term] id: CHEBI:38700 name: organic sodium salt namespace: chebi_ontology subset: 3_STAR synonym: "organic sodium salt" EXACT [ChEBI] synonym: "organic sodium salts" RELATED [ChEBI] is_a: CHEBI:24868 ! organic salt is_a: CHEBI:26714 ! sodium salt [Term] id: CHEBI:38716 name: carboxylic acid dianion namespace: chebi_ontology def: "Any dianion containing at least one carboxy group." [] subset: 3_STAR synonym: "carboxylic acid dianion" EXACT [ChEBI] synonym: "carboxylic acid dianions" RELATED [ChEBI] is_a: CHEBI:29067 ! carboxylic acid anion [Term] id: CHEBI:38958 name: indole alkaloid namespace: chebi_ontology alt_id: CHEBI:24795 alt_id: CHEBI:5901 def: "An alkaloid containing an indole skeleton." [] subset: 3_STAR synonym: "Indole alkaloid" EXACT [KEGG_COMPOUND] synonym: "indole alkaloids" RELATED [ChEBI] xref: KEGG:C06073 xref: Wikipedia:Indole_alkaloid is_a: CHEBI:22315 ! alkaloid relationship: has_part CHEBI:73398 ! indole skeleton [Term] id: CHEBI:39141 name: Bronsted acid namespace: chebi_ontology def: "A molecular entity capable of donating a hydron to an acceptor (Bronsted base)." [] subset: 3_STAR synonym: "acide de Bronsted" RELATED [IUPAC] synonym: "Bronsted acid" EXACT IUPAC_NAME [IUPAC] synonym: "Bronsted-Saeure" RELATED [ChEBI] synonym: "donneur d'hydron" RELATED [IUPAC] synonym: "hydron donor" RELATED [IUPAC] is_a: CHEBI:17891 ! donor is_a: CHEBI:37527 ! acid [Term] id: CHEBI:39142 name: Bronsted base namespace: chebi_ontology def: "A molecular entity capable of accepting a hydron from a donor (Bronsted acid)." [] subset: 3_STAR synonym: "accepteur d'hydron" RELATED [IUPAC] synonym: "base de Bronsted" RELATED [IUPAC] synonym: "Bronsted base" EXACT IUPAC_NAME [IUPAC] synonym: "Bronsted-Base" RELATED [ChEBI] synonym: "hydron acceptor" RELATED [IUPAC] is_a: CHEBI:15339 ! acceptor is_a: CHEBI:22695 ! base [Term] id: CHEBI:39144 name: Lewis base namespace: chebi_ontology def: "A molecular entity able to provide a pair of electrons and thus capable of forming a covalent bond with an electron-pair acceptor (Lewis acid), thereby producing a Lewis adduct." [] subset: 3_STAR synonym: "base de Lewis" RELATED [IUPAC] synonym: "donneur d'une paire d'electrons" RELATED [ChEBI] synonym: "electron donor" RELATED [ChEBI] synonym: "Lewis base" EXACT IUPAC_NAME [IUPAC] synonym: "Lewis-Base" RELATED [ChEBI] is_a: CHEBI:17891 ! donor is_a: CHEBI:22695 ! base [Term] id: CHEBI:39745 name: dihydrogenphosphate namespace: chebi_ontology alt_id: CHEBI:29137 alt_id: CHEBI:39739 def: "A monovalent inorganic anion that consists of phosphoric acid in which one of the three OH groups has been deprotonated." [] subset: 3_STAR synonym: "[PO2(OH)2](-)" RELATED [IUPAC] synonym: "dihydrogen(tetraoxidophosphate)(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "dihydrogenphosphate" EXACT IUPAC_NAME [IUPAC] synonym: "DIHYDROGENPHOSPHATE ION" RELATED [PDBeChem] synonym: "dihydrogentetraoxophosphate(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "dihydrogentetraoxophosphate(V)" EXACT IUPAC_NAME [IUPAC] synonym: "dihydroxidodioxidophosphate(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "H2PO4(-)" RELATED [IUPAC] xref: DrugBank:DB02831 xref: Gmelin:1999 {source="Gmelin"} xref: PDBeChem:2HP is_a: CHEBI:35780 ! phosphate ion is_a: CHEBI:79389 ! monovalent inorganic anion relationship: is_conjugate_acid_of CHEBI:43474 ! hydrogenphosphate property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "H2O4P" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "NBIIXXVUZAFLBC-UHFFFAOYSA-M" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "96.98724" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "96.96962" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]OP([O-])(=O)O[H]" xsd:string [Term] id: CHEBI:41609 name: carbonate namespace: chebi_ontology alt_id: CHEBI:29201 alt_id: CHEBI:41605 subset: 3_STAR synonym: "[CO3](2-)" RELATED [IUPAC] synonym: "carbonate" EXACT [IUPAC] synonym: "CARBONATE ION" RELATED [PDBeChem] synonym: "CO3(2-)" RELATED [ChEBI] synonym: "Karbonat" RELATED [ChEBI] synonym: "trioxidocarbonate(2-)" EXACT IUPAC_NAME [IUPAC] xref: Beilstein:3600898 {source="Beilstein"} xref: CAS:3812-32-6 {source="ChemIDplus"} xref: Gmelin:1559 {source="Gmelin"} xref: PDBeChem:CO3 is_a: CHEBI:35604 ! carbon oxoanion relationship: is_conjugate_base_of CHEBI:17544 ! hydrogencarbonate property_value: http://purl.obolibrary.org/obo/chebi/charge "-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CO3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "BVKZGUZCCUSVTD-UHFFFAOYSA-L" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "60.00890" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "59.98584" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]C([O-])=O" xsd:string [Term] id: CHEBI:43176 name: hydroxy group namespace: chebi_ontology alt_id: CHEBI:24706 alt_id: CHEBI:43171 subset: 3_STAR synonym: "-OH" RELATED [IUPAC] synonym: "hydroxy" EXACT IUPAC_NAME [IUPAC] synonym: "HYDROXY GROUP" EXACT [PDBeChem] synonym: "hydroxy group" EXACT [UniProt] synonym: "hydroxyl" RELATED [ChEBI] synonym: "hydroxyl group" RELATED [ChEBI] xref: PDBeChem:OH is_a: CHEBI:33246 ! inorganic group property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "HO" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "17.00734" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "17.00274" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "*O[H]" xsd:string [Term] id: CHEBI:43474 name: hydrogenphosphate namespace: chebi_ontology alt_id: CHEBI:29139 alt_id: CHEBI:43470 def: "A phosphate ion that is the conjugate base of dihydrogenphosphate." [] subset: 3_STAR synonym: "[P(OH)O3](2-)" RELATED [MolBase] synonym: "[PO3(OH)](2-)" RELATED [IUPAC] synonym: "HPO4(2-)" RELATED [IUPAC] synonym: "hydrogen phosphate" RELATED [ChEBI] synonym: "hydrogen(tetraoxidophosphate)(2-)" EXACT IUPAC_NAME [IUPAC] synonym: "hydrogenphosphate" EXACT IUPAC_NAME [IUPAC] synonym: "HYDROGENPHOSPHATE ION" RELATED [PDBeChem] synonym: "hydrogentetraoxophosphate(2-)" EXACT IUPAC_NAME [IUPAC] synonym: "hydrogentetraoxophosphate(V)" EXACT IUPAC_NAME [IUPAC] synonym: "hydroxidotrioxidophosphate(2-)" EXACT IUPAC_NAME [IUPAC] synonym: "INORGANIC PHOSPHATE GROUP" RELATED [PDBeChem] synonym: "phosphate" RELATED [UniProt] xref: Gmelin:1998 {source="Gmelin"} xref: MolBase:1628 xref: PDBeChem:PI xref: PDBeChem:PO4 is_a: CHEBI:35780 ! phosphate ion is_a: CHEBI:79388 ! divalent inorganic anion relationship: has_role CHEBI:23357 ! cofactor relationship: has_role CHEBI:75772 ! Saccharomyces cerevisiae metabolite relationship: is_conjugate_acid_of CHEBI:18367 ! phosphate(3-) relationship: is_conjugate_base_of CHEBI:39745 ! dihydrogenphosphate property_value: http://purl.obolibrary.org/obo/chebi/charge "-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "HO4P" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "NBIIXXVUZAFLBC-UHFFFAOYSA-L" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "95.97930" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "95.96234" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "OP([O-])([O-])=O" xsd:string [Term] id: CHEBI:45696 name: hydrogensulfate namespace: chebi_ontology alt_id: CHEBI:29199 alt_id: CHEBI:45693 subset: 3_STAR synonym: "[SO3(OH)](-)" RELATED [IUPAC] synonym: "HSO4(-)" RELATED [IUPAC] synonym: "HYDROGEN SULFATE" RELATED [PDBeChem] synonym: "hydrogen(tetraoxidosulfate)(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "hydrogensulfate" EXACT [IUPAC] synonym: "hydrogensulfate(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "hydrogentetraoxosulfate(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "hydrogentetraoxosulfate(VI)" EXACT IUPAC_NAME [IUPAC] synonym: "hydroxidotrioxidosulfate(1-)" EXACT IUPAC_NAME [IUPAC] xref: Gmelin:2121 {source="Gmelin"} is_a: CHEBI:33482 ! sulfur oxoanion relationship: is_conjugate_acid_of CHEBI:16189 ! sulfate relationship: is_conjugate_base_of CHEBI:26836 ! sulfuric acid property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "HO4S" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QAOWNCQODCNURD-UHFFFAOYSA-M" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "97.07154" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "96.96010" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]OS([O-])(=O)=O" xsd:string [Term] id: CHEBI:46629 name: oxo group namespace: chebi_ontology alt_id: CHEBI:29353 alt_id: CHEBI:44607 subset: 3_STAR synonym: "=O" RELATED [IUPAC] synonym: "oxo" EXACT IUPAC_NAME [IUPAC] synonym: "OXO GROUP" EXACT [PDBeChem] xref: PDBeChem:O is_a: CHEBI:33246 ! inorganic group property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "15.99940" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "15.99491" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "O=*" xsd:string [Term] id: CHEBI:46787 name: solvent namespace: chebi_ontology def: "A liquid that can dissolve other substances (solutes) without any change in their chemical composition." [] subset: 3_STAR synonym: "Loesungsmittel" RELATED [ChEBI] synonym: "solvant" RELATED [ChEBI] synonym: "solvents" RELATED [ChEBI] xref: Wikipedia:Solvent is_a: CHEBI:33232 ! application is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:46883 name: carboxy group namespace: chebi_ontology alt_id: CHEBI:23025 alt_id: CHEBI:41420 subset: 3_STAR synonym: "-C(O)OH" RELATED [IUPAC] synonym: "-CO2H" RELATED [ChEBI] synonym: "-COOH" RELATED [IUPAC] synonym: "carboxy" EXACT IUPAC_NAME [IUPAC] synonym: "CARBOXY GROUP" EXACT [PDBeChem] synonym: "carboxyl group" RELATED [ChEBI] xref: PDBeChem:FMT is_a: CHEBI:33249 ! organyl group property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CHO2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "45.01744" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "44.99765" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "*C(=O)O" xsd:string [Term] id: CHEBI:47622 name: acetate ester namespace: chebi_ontology alt_id: CHEBI:13244 alt_id: CHEBI:13799 alt_id: CHEBI:22189 alt_id: CHEBI:2406 def: "Any carboxylic ester where the carboxylic acid component is acetic acid." [] subset: 3_STAR synonym: "acetate" RELATED [ChEBI] synonym: "acetate esters" RELATED [ChEBI] synonym: "acetates" RELATED [ChEBI] synonym: "Acetic ester" RELATED [KEGG_COMPOUND] synonym: "Acetyl ester" RELATED [KEGG_COMPOUND] synonym: "acetyl esters" RELATED [ChEBI] synonym: "an acetyl ester" RELATED [UniProt] xref: KEGG:C01883 xref: Wikipedia:Acetate#Esters is_a: CHEBI:33308 ! carboxylic ester relationship: has_functional_parent CHEBI:15366 ! acetic acid property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H3O2R" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "59.04400" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "59.01330" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CC(=O)O[*]" xsd:string [Term] id: CHEBI:47891 name: steroid acid namespace: chebi_ontology def: "Any steroid substituted by at least one carboxy group." [] subset: 3_STAR synonym: "steroid acids" RELATED [ChEBI] is_a: CHEBI:35341 ! steroid is_a: CHEBI:64709 ! organic acid relationship: is_conjugate_acid_of CHEBI:50160 ! steroid acid anion [Term] id: CHEBI:48154 name: sulfur oxide namespace: chebi_ontology subset: 3_STAR synonym: "oxides of sulfur" RELATED [ChEBI] synonym: "Schwefeloxide" RELATED [ChEBI] synonym: "sulfur oxides" RELATED [ChEBI] is_a: CHEBI:24836 ! inorganic oxide is_a: CHEBI:26835 ! sulfur molecular entity [Term] id: CHEBI:48354 name: polar solvent namespace: chebi_ontology def: "A solvent that is composed of polar molecules. Polar solvents can dissolve ionic compounds or ionisable covalent compounds." [] subset: 3_STAR synonym: "polar solvent" EXACT IUPAC_NAME [IUPAC] synonym: "polar solvents" RELATED [ChEBI] is_a: CHEBI:46787 ! solvent [Term] id: CHEBI:48356 name: protic solvent namespace: chebi_ontology def: "A polar solvent that is capable of acting as a hydron (proton) donor." [] subset: 3_STAR synonym: "protogenic solvent" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:39141 ! Bronsted acid is_a: CHEBI:48354 ! polar solvent [Term] id: CHEBI:48539 name: alpha-adrenergic drug namespace: chebi_ontology def: "Any drug that acts on an alpha-adrenergic receptor." [] subset: 3_STAR synonym: "alpha-adrenergic drugs" RELATED [ChEBI] is_a: CHEBI:37962 ! adrenergic agent [Term] id: CHEBI:48705 name: agonist namespace: chebi_ontology def: "Substance which binds to cell receptors normally responding to naturally occurring substances and which produces a response of its own." [] subset: 3_STAR synonym: "agonist" EXACT IUPAC_NAME [IUPAC] synonym: "agonista" RELATED [ChEBI] synonym: "agoniste" RELATED [ChEBI] synonym: "agonists" RELATED [ChEBI] is_a: CHEBI:52210 ! pharmacological role [Term] id: CHEBI:49637 name: hydrogen atom namespace: chebi_ontology alt_id: CHEBI:24634 alt_id: CHEBI:49636 subset: 3_STAR synonym: "1H" RELATED [IUPAC] synonym: "H" RELATED [IUPAC] synonym: "hidrogeno" RELATED [ChEBI] synonym: "hydrogen" EXACT IUPAC_NAME [IUPAC] synonym: "hydrogen" RELATED [ChEBI] synonym: "hydrogene" RELATED [ChEBI] synonym: "Wasserstoff" RELATED [ChEBI] xref: WebElements:H is_a: CHEBI:24835 ! inorganic molecular entity is_a: CHEBI:25585 ! nonmetal atom is_a: CHEBI:33559 ! s-block element atom relationship: has_role CHEBI:33937 ! macronutrient property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "H" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "YZCKVEUIGOORGS-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "1.00794" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "1.00783" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]" xsd:string [Term] id: CHEBI:50047 name: organic amino compound namespace: chebi_ontology def: "A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by organyl groups." [] subset: 3_STAR synonym: "organic amino compounds" RELATED [ChEBI] is_a: CHEBI:35352 ! organonitrogen compound relationship: has_parent_hydride CHEBI:16134 ! ammonia relationship: has_role CHEBI:39142 ! Bronsted base [Term] id: CHEBI:50160 name: steroid acid anion namespace: chebi_ontology def: "Any anion formed by loss of a proton from a steroid acid." [] subset: 3_STAR synonym: "steroid acid anions" RELATED [ChEBI] is_a: CHEBI:29067 ! carboxylic acid anion relationship: is_conjugate_base_of CHEBI:47891 ! steroid acid [Term] id: CHEBI:50297 name: canonical nucleotide residue namespace: chebi_ontology subset: 3_STAR synonym: "canonical nucleotide residues" RELATED [ChEBI] is_a: CHEBI:50319 ! nucleotide residue [Term] id: CHEBI:50298 name: canonical deoxyribonucleotide residue namespace: chebi_ontology subset: 3_STAR synonym: "canonical deoxyribonucleotide residues" RELATED [ChEBI] is_a: CHEBI:50297 ! canonical nucleotide residue [Term] id: CHEBI:50299 name: canonical ribonucleotide residue namespace: chebi_ontology subset: 3_STAR synonym: "canonical ribonucleotide residues" RELATED [ChEBI] is_a: CHEBI:50297 ! canonical nucleotide residue [Term] id: CHEBI:50312 name: onium compound namespace: chebi_ontology subset: 1_STAR is_a: CHEBI:37577 ! heteroatomic molecular entity [Term] id: CHEBI:50313 name: onium cation namespace: chebi_ontology def: "Mononuclear cations derived by addition of a hydron to a mononuclear parent hydride of the pnictogen, chalcogen and halogen families." [] subset: 3_STAR synonym: "onium cations" EXACT IUPAC_NAME [IUPAC] synonym: "onium cations" RELATED [ChEBI] synonym: "onium ion" RELATED [ChEBI] synonym: "onium ions" RELATED [ChEBI] is_a: CHEBI:50312 ! onium compound [Term] id: CHEBI:50319 name: nucleotide residue namespace: chebi_ontology subset: 3_STAR synonym: "nucleotide residues" RELATED [ChEBI] is_a: CHEBI:33247 ! organic group [Term] id: CHEBI:50320 name: nucleoside residue namespace: chebi_ontology subset: 3_STAR synonym: "nucleoside residues" RELATED [ChEBI] is_a: CHEBI:33247 ! organic group [Term] id: CHEBI:50514 name: vasoconstrictor agent namespace: chebi_ontology def: "Drug used to cause constriction of the blood vessels." [] subset: 3_STAR is_a: CHEBI:35554 ! cardiovascular drug [Term] id: CHEBI:50860 name: organic molecular entity namespace: chebi_ontology alt_id: CHEBI:25700 alt_id: CHEBI:33244 def: "Any molecular entity that contains carbon." [] subset: 3_STAR synonym: "organic compounds" RELATED [ChEBI] synonym: "organic entity" RELATED [ChEBI] synonym: "organic molecular entities" RELATED [ChEBI] is_a: CHEBI:33582 ! carbon group molecular entity relationship: has_part CHEBI:27594 ! carbon atom [Term] id: CHEBI:50906 name: role namespace: chebi_ontology def: "A role is particular behaviour which a material entity may exhibit." [] subset: 3_STAR is_a: PATO:0000001 ! quality [Term] id: CHEBI:50910 name: neurotoxin namespace: chebi_ontology alt_id: CHEBI:50911 def: "A poison that interferes with the functions of the nervous system." [] subset: 3_STAR synonym: "agente neurotoxico" RELATED [ChEBI] synonym: "nerve poison" RELATED [ChEBI] synonym: "nerve poisons" RELATED [ChEBI] synonym: "neurotoxic agent" RELATED [ChEBI] synonym: "neurotoxic agents" RELATED [ChEBI] synonym: "neurotoxicant" RELATED [ChEBI] synonym: "neurotoxins" RELATED [ChEBI] xref: Wikipedia:Neurotoxin is_a: CHEBI:52209 ! aetiopathogenetic role is_a: CHEBI:64909 ! poison [Term] id: CHEBI:50994 name: primary amino compound namespace: chebi_ontology def: "A compound formally derived from ammonia by replacing one hydrogen atom by an organyl group." [] subset: 3_STAR synonym: "primary amino compounds" RELATED [ChEBI] is_a: CHEBI:50047 ! organic amino compound relationship: is_conjugate_base_of CHEBI:65296 ! primary ammonium ion [Term] id: CHEBI:51086 name: chemical role namespace: chebi_ontology def: "A role played by the molecular entity or part thereof within a chemical context." [] subset: 3_STAR is_a: CHEBI:50906 ! role [Term] id: CHEBI:51143 name: nitrogen molecular entity namespace: chebi_ontology alt_id: CHEBI:25556 alt_id: CHEBI:7594 subset: 3_STAR synonym: "nitrogen compounds" RELATED [ChEBI] synonym: "nitrogen molecular entities" RELATED [ChEBI] synonym: "Nitrogenous compounds" RELATED [KEGG_COMPOUND] xref: KEGG:C06061 is_a: CHEBI:33302 ! pnictogen molecular entity relationship: has_part CHEBI:25555 ! nitrogen atom [Term] id: CHEBI:51151 name: dipolar compound namespace: chebi_ontology def: "An organic molecule that is electrically neutral carrying a positive and a negative charge in one of its major canonical descriptions. In most dipolar compounds the charges are delocalized; however the term is also applied to species where this is not the case." [] subset: 3_STAR synonym: "dipolar compounds" RELATED [ChEBI] is_a: CHEBI:72695 ! organic molecule [Term] id: CHEBI:51422 name: organodiyl group namespace: chebi_ontology def: "Any organic substituent group, regardless of functional type, having two free valences at carbon atom(s)." [] subset: 3_STAR synonym: "organodiyl groups" RELATED [ChEBI] is_a: CHEBI:51446 ! organic divalent group [Term] id: CHEBI:51446 name: organic divalent group namespace: chebi_ontology subset: 1_STAR is_a: CHEBI:33247 ! organic group [Term] id: CHEBI:51447 name: organic univalent group namespace: chebi_ontology subset: 1_STAR is_a: CHEBI:33247 ! organic group [Term] id: CHEBI:51958 name: organic polycyclic compound namespace: chebi_ontology subset: 3_STAR synonym: "organic polycyclic compounds" RELATED [ChEBI] is_a: CHEBI:33635 ! polycyclic compound is_a: CHEBI:33832 ! organic cyclic compound [Term] id: CHEBI:52206 name: biochemical role namespace: chebi_ontology def: "A biological role played by the molecular entity or part thereof within a biochemical context." [] subset: 3_STAR is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:52209 name: aetiopathogenetic role namespace: chebi_ontology def: "A role played by the molecular entity or part thereof which causes the development of a pathological process." [] subset: 3_STAR synonym: "etiopathogenetic agent" RELATED [ChEBI] synonym: "etiopathogenetic role" RELATED [ChEBI] is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:52210 name: pharmacological role namespace: chebi_ontology def: "A biological role which describes how a drug interacts within a biological system and how the interactions affect its medicinal properties." [] subset: 3_STAR is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:52211 name: physiological role namespace: chebi_ontology subset: 1_STAR is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:52217 name: pharmaceutical namespace: chebi_ontology alt_id: CHEBI:33293 alt_id: CHEBI:33294 def: "Any substance introduced into a living organism with therapeutic or diagnostic purpose." [] subset: 3_STAR synonym: "farmaco" RELATED [ChEBI] synonym: "medicament" RELATED [ChEBI] synonym: "pharmaceuticals" RELATED [ChEBI] is_a: CHEBI:33232 ! application [Term] id: CHEBI:52845 name: cyclic organic group namespace: chebi_ontology def: "An organic group that consists of a closed ring. It may be a substituent or a skeleton." [] subset: 3_STAR synonym: "cyclic organic groups" RELATED [ChEBI] is_a: CHEBI:33247 ! organic group [Term] id: CHEBI:53000 name: epitope namespace: chebi_ontology def: "The biological role played by a material entity when bound by a receptor of the adaptive immune system. Specific site on an antigen to which an antibody binds." [] subset: 3_STAR synonym: "antigenic determinant" RELATED [ChEBI] synonym: "epitope function" RELATED [ChEBI] synonym: "epitope role" RELATED [ChEBI] is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:53309 name: polyanionic macromolecule namespace: chebi_ontology def: "A polymer carrying multiple negative charges." [] subset: 3_STAR synonym: "polyanion" RELATED [ChEBI] synonym: "polyanions" RELATED [SUBMITTER] is_a: CHEBI:53368 ! ionic macromolecule [Term] id: CHEBI:53368 name: ionic macromolecule namespace: chebi_ontology def: "A macromolecule containing ionic groups." [] subset: 3_STAR synonym: "ionic polymer" RELATED [ChEBI] synonym: "polyionic macromolecule" RELATED [ChEBI] is_a: CHEBI:33839 ! macromolecule [Term] id: CHEBI:5391 name: glucagon namespace: chebi_ontology def: "A 29-amino acid peptide hormone consisting of His, Ser, Gln, Gly, Thr, Phe, Thr, Ser, Asp, Tyr, Ser, Lys, Tyr, Leu, Asp, Ser, Arg, Arg, Ala, Gln, Asp, Phe, Val, Gln, Trp, Leu, Met, Asn and Thr residues joined in sequence." [] subset: 3_STAR synonym: "Glucagon" EXACT [KEGG_COMPOUND] synonym: "glucagon" RELATED INN [ChemIDplus] synonym: "Glucagone" RELATED [ChemIDplus] synonym: "glucagonum" RELATED INN [ChemIDplus] synonym: "His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr" RELATED [ChEBI] synonym: "His-ser-glu(nh2)-gly-thr-phe-thr-ser-asp-tyr-ser-lys-tyr-leu-asp-ser-arg-arg-ala-glu(NH2)-asp-phe-val-glu(NH2)-trp-leu-met-asp(NH2)-thr" RELATED [ChemIDplus] synonym: "HSQGTFTSDYSKYLDSRRAQDFVQWLMNT" RELATED [ChEBI] synonym: "L-histidyl-L-seryl-L-glutaminylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-alpha-aspartyl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-glutaminyl-L-alpha-aspartyl-L-phenylalanyl-L-valyl-L-glutaminyl-L-tryptophyl-L-leucyl-L-methionyl-L-asparaginyl-L-threonine" EXACT IUPAC_NAME [IUPAC] xref: CAS:16941-32-5 {source="ChemIDplus"} xref: CAS:9007-92-5 {source="KEGG COMPOUND"} xref: CAS:9007-92-5 {source="ChemIDplus"} xref: Drug_Central:2994 {source="DrugCentral"} xref: DrugBank:DB00040 xref: KEGG:C01501 xref: KEGG:D00116 xref: PMID:21940356 {source="Europe PMC"} xref: PMID:22014161 {source="Europe PMC"} xref: PMID:22154917 {source="Europe PMC"} xref: PMID:22166985 {source="Europe PMC"} xref: PMID:22167521 {source="Europe PMC"} xref: PMID:22214853 {source="Europe PMC"} xref: PMID:22227186 {source="Europe PMC"} xref: PMID:22286080 {source="Europe PMC"} xref: PMID:22294753 {source="Europe PMC"} xref: PMID:22318544 {source="Europe PMC"} xref: PMID:22334714 {source="Europe PMC"} xref: PMID:22399501 {source="Europe PMC"} xref: PMID:22438981 {source="Europe PMC"} xref: PMID:22454291 {source="Europe PMC"} xref: Reaxys:13191924 {source="Reaxys"} xref: Wikipedia:Glucagon is_a: CHEBI:25905 ! peptide hormone property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C153H225N43O49S" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C153H225N43O49S/c1-72(2)52-97(133(226)176-96(47-51-246-11)132(225)184-104(60-115(159)209)143(236)196-123(78(10)203)151(244)245)179-137(230)103(58-83-64-167-89-29-19-18-28-87(83)89)183-131(224)95(43-46-114(158)208)177-148(241)120(74(5)6)194-141(234)101(54-79-24-14-12-15-25-79)182-138(231)105(61-117(211)212)185-130(223)94(42-45-113(157)207)171-124(217)75(7)170-127(220)91(31-22-49-165-152(160)161)172-128(221)92(32-23-50-166-153(162)163)174-146(239)110(69-199)191-140(233)107(63-119(215)216)186-134(227)98(53-73(3)4)178-135(228)99(56-81-33-37-85(204)38-34-81)180-129(222)90(30-20-21-48-154)173-145(238)109(68-198)190-136(229)100(57-82-35-39-86(205)40-36-82)181-139(232)106(62-118(213)214)187-147(240)111(70-200)192-150(243)122(77(9)202)195-142(235)102(55-80-26-16-13-17-27-80)188-149(242)121(76(8)201)193-116(210)66-168-126(219)93(41-44-112(156)206)175-144(237)108(67-197)189-125(218)88(155)59-84-65-164-71-169-84/h12-19,24-29,33-40,64-65,71-78,88,90-111,120-123,167,197-205H,20-23,30-32,41-63,66-70,154-155H2,1-11H3,(H2,156,206)(H2,157,207)(H2,158,208)(H2,159,209)(H,164,169)(H,168,219)(H,170,220)(H,171,217)(H,172,221)(H,173,238)(H,174,239)(H,175,237)(H,176,226)(H,177,241)(H,178,228)(H,179,230)(H,180,222)(H,181,232)(H,182,231)(H,183,224)(H,184,225)(H,185,223)(H,186,227)(H,187,240)(H,188,242)(H,189,218)(H,190,229)(H,191,233)(H,192,243)(H,193,210)(H,194,234)(H,195,235)(H,196,236)(H,211,212)(H,213,214)(H,215,216)(H,244,245)(H4,160,161,165)(H4,162,163,166)/t75-,76+,77+,78+,88-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,120-,121-,122-,123-/m0/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "MASNOZXLGMXCHN-ZLPAWPGGSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "3482.74700" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "3480.61570" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(O)=O" xsd:string [Term] id: CHEBI:5686 name: heterocyclic compound namespace: chebi_ontology def: "A cyclic compound having as ring members atoms of at least two different elements." [] subset: 3_STAR synonym: "compuesto heterociclico" RELATED [IUPAC] synonym: "compuestos heterociclicos" RELATED [IUPAC] synonym: "heterocycle" RELATED [ChEBI] synonym: "Heterocyclic compound" EXACT [KEGG_COMPOUND] synonym: "heterocyclic compounds" RELATED [ChEBI] is_a: CHEBI:33595 ! cyclic compound [Term] id: CHEBI:57887 name: tryptaminium namespace: chebi_ontology def: "An ammonium ion that is the conjugate acid of tryptamine arising from protonation of the primary amino group; major species at pH 7.3." [] subset: 3_STAR synonym: "2-(1H-indol-3-yl)ethanaminium" EXACT IUPAC_NAME [IUPAC] synonym: "tryptamine" RELATED [UniProt] synonym: "tryptaminium cation" RELATED [ChEBI] synonym: "tryptaminium(1+)" RELATED [ChEBI] xref: Gmelin:533978 {source="Gmelin"} is_a: CHEBI:65296 ! primary ammonium ion relationship: has_role CHEBI:75771 ! mouse metabolite relationship: has_role CHEBI:76924 ! plant metabolite relationship: has_role CHEBI:77746 ! human metabolite relationship: is_conjugate_acid_of CHEBI:16765 ! tryptamine property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C10H13N2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2/p+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "APJYDQYYACXCRM-UHFFFAOYSA-O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "161.22310" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "161.10732" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[NH3+]CCc1c[nH]c2ccccc12" xsd:string [Term] id: CHEBI:57977 name: bilirubin(2-) namespace: chebi_ontology def: "A dicarboxylic acid dianion obtained by deprotonation of the two carboxy groups of bilirubin; major species at pH 7.3." [] subset: 3_STAR synonym: "2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-1,10,19,22,23,24-hexahydro-21H-biline-8,12-dipropanoate" RELATED [ChEBI] synonym: "bilirubin dianion" RELATED [ChEBI] synonym: "bilirubin IXalpha" RELATED [UniProt] xref: Beilstein:4083310 {source="Beilstein"} is_a: CHEBI:28965 ! dicarboxylic acid dianion is_a: CHEBI:59252 ! linear tetrapyrrole anion relationship: has_role CHEBI:77746 ! human metabolite relationship: is_conjugate_base_of CHEBI:16990 ! bilirubin IXalpha property_value: http://purl.obolibrary.org/obo/chebi/charge "-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C33H34N4O6" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C33H36N4O6/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26/h7-8,13-14,34-35H,1-2,9-12,15H2,3-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41)/p-2/b26-13-,27-14-" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "BPYKTIZUTYGOLE-IFADSCNNSA-L" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "582.64630" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "582.24893" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CC1=C(C=C)\\C(NC1=O)=C\\c1[nH]c(Cc2[nH]c(\\C=C3NC(=O)C(C=C)=C/3C)c(C)c2CCC([O-])=O)c(CCC([O-])=O)c1C" xsd:string [Term] id: CHEBI:58958 name: organosulfate oxoanion namespace: chebi_ontology def: "An organic anion of general formula RS(=O)2O(-) where R is an organyl group." [] subset: 3_STAR synonym: "organosulfate oxoanions" RELATED [ChEBI] is_a: CHEBI:25696 ! organic anion is_a: CHEBI:33482 ! sulfur oxoanion relationship: has_functional_parent CHEBI:16189 ! sulfate relationship: is_conjugate_base_of CHEBI:25704 ! organic sulfate property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "O4SR" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "96.06300" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "95.95173" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]S(=O)(=O)O[*]" xsd:string [Term] id: CHEBI:59252 name: linear tetrapyrrole anion namespace: chebi_ontology def: "An organic anion arising from deprotonation of a acyclic tetrapyrrole compound." [] subset: 3_STAR synonym: "acyclic tetrapyrrole anion" RELATED [ChEBI] synonym: "acyclic tetrapyrrole anions" RELATED [ChEBI] synonym: "linear tetrapyrrole anions" RELATED [ChEBI] is_a: CHEBI:25696 ! organic anion [Term] id: CHEBI:59698 name: phosphoric acids namespace: chebi_ontology def: "Compounds containing one or more phosphoric acid units." [] subset: 3_STAR is_a: CHEBI:33457 ! phosphorus oxoacid [Term] id: CHEBI:59740 name: nucleophilic reagent namespace: chebi_ontology def: "A reagent that forms a bond to its reaction partner (the electrophile) by donating both bonding electrons." [] subset: 3_STAR synonym: "nucleophile" RELATED [ChEBI] synonym: "nucleophiles" RELATED [ChEBI] synonym: "nucleophilic reagents" RELATED [ChEBI] is_a: CHEBI:33893 ! reagent is_a: CHEBI:39144 ! Lewis base [Term] id: CHEBI:59999 name: chemical substance namespace: chebi_ontology def: "A chemical substance is a portion of matter of constant composition, composed of molecular entities of the same type or of different types." [] subset: 3_STAR synonym: "Chemische Substanz" RELATED [ChEBI] is_a: CHEBI:24431 ! chemical entity [Term] id: CHEBI:60004 name: mixture namespace: chebi_ontology def: "A mixture is a chemical substance composed of multiple molecules, at least two of which are of a different kind." [] subset: 3_STAR synonym: "Mischung" RELATED [ChEBI] is_a: CHEBI:59999 ! chemical substance [Term] id: CHEBI:60027 name: polymer namespace: chebi_ontology def: "A polymer is a mixture, which is composed of macromolecules of different kinds and which may be differentiated by composition, length, degree of branching etc.." [] subset: 3_STAR synonym: "Kunststoff" RELATED [ChEBI] synonym: "Polymer" EXACT [ChEBI] xref: Wikipedia:Polymer is_a: CHEBI:60004 ! mixture relationship: has_part CHEBI:33839 ! macromolecule [Term] id: CHEBI:60164 name: ionic polymer namespace: chebi_ontology def: "An ionic polymer is a polymer, composed of ionic macromolecules." [] subset: 3_STAR synonym: "polyionic polymer" RELATED [ChEBI] is_a: CHEBI:60027 ! polymer relationship: has_part CHEBI:53368 ! ionic macromolecule [Term] id: CHEBI:60242 name: monovalent inorganic cation namespace: chebi_ontology def: "An atom or small molecule with a positive charge that does not contain carbon in covalent linkage, with a valency of one." [] subset: 3_STAR synonym: "a monovalent cation" RELATED [UniProt] is_a: CHEBI:36915 ! inorganic cation [Term] id: CHEBI:60466 name: peptide zwitterion namespace: chebi_ontology def: "Zwitterionic form of any peptide where, in general, the amino terminus is positively charged and the carboxy terminus is negatively charged." [] subset: 3_STAR synonym: "a peptide" RELATED [UniProt] synonym: "peptide zwitterions" RELATED [ChEBI] is_a: CHEBI:27369 ! zwitterion relationship: is_tautomer_of CHEBI:16670 ! peptide property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H4NO2R(C2H2NOR)n" xsd:string [Term] id: CHEBI:60926 name: amino monosaccharide namespace: chebi_ontology def: "Any amino sugar that is a monosaccharide in which one alcoholic hydroxy group is replaced by an amino group." [] subset: 3_STAR synonym: "amino monosaccharides" RELATED [ChEBI] is_a: CHEBI:28963 ! amino sugar [Term] id: CHEBI:61120 name: nucleobase-containing molecular entity namespace: chebi_ontology def: "Any compound that has a nucleobase as a part." [] subset: 3_STAR synonym: "nucleobase-containing compound" RELATED [SUBMITTER] synonym: "nucleobase-containing compounds" RELATED [ChEBI] synonym: "nucleobase-containing molecular entities" RELATED [ChEBI] is_a: CHEBI:33833 ! heteroarene is_a: CHEBI:51143 ! nitrogen molecular entity relationship: has_functional_parent CHEBI:18282 ! nucleobase [Term] id: CHEBI:61469 name: polyanionic polymer namespace: chebi_ontology def: "A polymer, composed of polyanion macromolecules." [] subset: 3_STAR synonym: "polyanion" RELATED [ChEBI] synonym: "polyanions" RELATED [ChEBI] is_a: CHEBI:60164 ! ionic polymer relationship: has_part CHEBI:53309 ! polyanionic macromolecule [Term] id: CHEBI:63248 name: oxidising agent namespace: chebi_ontology def: "A substance that removes electrons from another reactant in a redox reaction." [] subset: 3_STAR synonym: "oxidant" RELATED [ChEBI] synonym: "oxidants" RELATED [ChEBI] synonym: "oxidiser" RELATED [ChEBI] synonym: "oxidisers" RELATED [ChEBI] synonym: "oxidising agents" RELATED [ChEBI] synonym: "oxidizer" RELATED [ChEBI] synonym: "oxidizers" RELATED [ChEBI] synonym: "oxidizing agent" RELATED [ChEBI] synonym: "oxidizing agents" RELATED [ChEBI] is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:63299 name: carbohydrate derivative namespace: chebi_ontology def: "Any organooxygen compound derived from a carbohydrate by replacement of one or more hydroxy group(s) by an amino group, a thiol group or similar heteroatomic groups. The term also includes derivatives of these compounds." [] subset: 3_STAR synonym: "carbohydrate derivatives" RELATED [ChEBI] synonym: "derivatised carbohydrate" RELATED [ChEBI] synonym: "derivatised carbohydrates" RELATED [ChEBI] synonym: "derivatized carbohydrate" RELATED [ChEBI] synonym: "derivatized carbohydrates" RELATED [ChEBI] is_a: CHEBI:78616 ! carbohydrates and carbohydrate derivatives relationship: has_functional_parent CHEBI:16646 ! carbohydrate [Term] id: CHEBI:63436 name: carbohydrate acid derivative namespace: chebi_ontology def: "A carbohydrate derivative that is formally obtained from a carbohydrate acid." [] subset: 3_STAR synonym: "carbohydrate acid derivatives" RELATED [ChEBI] is_a: CHEBI:63299 ! carbohydrate derivative relationship: has_functional_parent CHEBI:33720 ! carbohydrate acid relationship: is_conjugate_acid_of CHEBI:63551 ! carbohydrate acid derivative anion [Term] id: CHEBI:63534 name: monoamine namespace: chebi_ontology def: "An aralylamino compound which contains one amino group connected to an aromatic ring by a two-carbon chain. Monoamines are derived from aromatic amino acids like phenylalanine, tyrosine, tryptophan, and the thyroid hormones by the action of aromatic amino acid decarboxylase enzymes." [] subset: 3_STAR synonym: "monoamines" RELATED [ChEBI] synonym: "naturally occurring monoamine" RELATED [ChEBI] synonym: "naturally occurring monoamines" RELATED [ChEBI] xref: PMID:21822758 {source="Europe PMC"} xref: PMID:21993877 {source="Europe PMC"} xref: PMID:22005599 {source="Europe PMC"} xref: PMID:22082101 {source="Europe PMC"} xref: PMID:22153577 {source="Europe PMC"} xref: PMID:22213370 {source="Europe PMC"} xref: PMID:22218931 {source="Europe PMC"} xref: PMID:22342987 {source="Europe PMC"} xref: PMID:22371656 {source="Europe PMC"} is_a: CHEBI:64365 ! aralkylamino compound [Term] id: CHEBI:63551 name: carbohydrate acid derivative anion namespace: chebi_ontology def: "A carboxylic acid anion resulting from the deprotonation of the carboxy group of a carbohydrate acid derivative." [] subset: 3_STAR synonym: "carbohydrate acid anion derivative" RELATED [ChEBI] synonym: "carbohydrate acid anion derivatives" RELATED [ChEBI] synonym: "carbohydrate acid derivative anions" RELATED [ChEBI] is_a: CHEBI:29067 ! carboxylic acid anion relationship: has_functional_parent CHEBI:33721 ! carbohydrate acid anion relationship: is_conjugate_base_of CHEBI:63436 ! carbohydrate acid derivative [Term] id: CHEBI:64047 name: food additive namespace: chebi_ontology def: "Any substance which is added to food to preserve or enhance its flavour and/or appearance." [] subset: 3_STAR synonym: "food additives" RELATED [ChEBI] xref: Wikipedia:Food_additive is_a: CHEBI:33232 ! application is_a: CHEBI:78295 ! food component [Term] id: CHEBI:64049 name: food acidity regulator namespace: chebi_ontology def: "A food additive that is used to change or otherwise control the acidity or alkalinity of foods. They may be acids, bases, neutralising agents or buffering agents." [] subset: 3_STAR synonym: "acidity regulator" RELATED [ChEBI] synonym: "acidity regulators" RELATED [ChEBI] synonym: "food acidity regulators" RELATED [ChEBI] synonym: "pH control agent" RELATED [ChEBI] synonym: "pH control agents" RELATED [ChEBI] xref: Wikipedia:Acidity_regulator is_a: CHEBI:64047 ! food additive [Term] id: CHEBI:64365 name: aralkylamino compound namespace: chebi_ontology def: "An organic amino compound in which an aminoalkyl group is linked to an arene." [] subset: 3_STAR synonym: "aralkylamino compounds" RELATED [ChEBI] is_a: CHEBI:50047 ! organic amino compound [Term] id: CHEBI:64628 name: somatostatin namespace: chebi_ontology def: "A fourteen-membered heterodetic cyclic peptide comprising the sequence Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys cyclised by a disulfide bridge between the two Cys residues at positions 3 and 14." [] subset: 3_STAR synonym: "Ala-Gly-cyclo-[Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys]" RELATED [ChEBI] synonym: "L-alanyl-N-[(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-13,25,28-tribenzyl-4-carboxy-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacontan-37-yl]glycinamide" EXACT IUPAC_NAME [IUPAC] synonym: "L-alanylglycyl-L-cysteinyl-L-lysyl-L-asparaginyl-L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-cysteine cyclic (3-14) disulfide" RELATED [ChemIDplus] synonym: "somatostatin" RELATED INN [KEGG_DRUG] synonym: "Somatostatin-1" RELATED [KEGG_COMPOUND] synonym: "Somatostatin-14" RELATED [KEGG_COMPOUND] synonym: "somatostatina" RELATED INN [ChemIDplus] synonym: "somatostatine" RELATED INN [ChemIDplus] synonym: "somatostatinum" RELATED INN [ChemIDplus] synonym: "Synthetic growth hormone release-inhibiting hormone" RELATED [ChemIDplus] xref: CAS:38916-34-6 {source="KEGG DRUG"} xref: CAS:38916-34-6 {source="ChemIDplus"} xref: Drug_Central:2997 {source="DrugCentral"} xref: HMDB:HMDB0013072 xref: KEGG:C16022 xref: KEGG:D07431 xref: LINCS:LSM-5326 xref: PMID:21922516 {source="Europe PMC"} xref: PMID:22129035 {source="Europe PMC"} xref: PMID:22147011 {source="Europe PMC"} xref: PMID:22251942 {source="Europe PMC"} xref: PMID:22483686 {source="Europe PMC"} xref: PMID:22509294 {source="Europe PMC"} xref: Reaxys:10148626 {source="Reaxys"} xref: Wikipedia:Somatostatin is_a: CHEBI:24533 ! heterodetic cyclic peptide is_a: CHEBI:25905 ! peptide hormone property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C76H104N18O19S2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C76H104N18O19S2/c1-41(79)64(100)82-37-61(99)83-58-39-114-115-40-59(76(112)113)92-72(108)57(38-95)91-75(111)63(43(3)97)94-71(107)54(33-46-23-11-6-12-24-46)90-74(110)62(42(2)96)93-66(102)51(28-16-18-30-78)84-69(105)55(34-47-36-81-49-26-14-13-25-48(47)49)88-68(104)53(32-45-21-9-5-10-22-45)86-67(103)52(31-44-19-7-4-8-20-44)87-70(106)56(35-60(80)98)89-65(101)50(85-73(58)109)27-15-17-29-77/h4-14,19-26,36,41-43,50-59,62-63,81,95-97H,15-18,27-35,37-40,77-79H2,1-3H3,(H2,80,98)(H,82,100)(H,83,99)(H,84,105)(H,85,109)(H,86,103)(H,87,106)(H,88,104)(H,89,101)(H,90,110)(H,91,111)(H,92,108)(H,93,102)(H,94,107)(H,112,113)/t41-,42+,43+,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-,63-/m0/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "NHXLMOGPVYXJNR-ATOGVRKGSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "1637.87800" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "1636.71666" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)[C@@H](C)O)C(O)=O)NC(=O)CNC(=O)[C@H](C)N" xsd:string [Term] id: CHEBI:64708 name: one-carbon compound namespace: chebi_ontology def: "An organic molecular entity containing a single carbon atom (C1)." [] subset: 3_STAR synonym: "one-carbon compounds" RELATED [ChEBI] is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:64709 name: organic acid namespace: chebi_ontology def: "Any organic molecular entity that is acidic and contains carbon in covalent linkage." [] subset: 3_STAR synonym: "organic acids" RELATED [ChEBI] is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:64909 name: poison namespace: chebi_ontology def: "Any substance that causes disturbance to organisms by chemical reaction or other activity on the molecular scale, when a sufficient quantity is absorbed by the organism." [] subset: 3_STAR synonym: "poisonous agent" RELATED [ChEBI] synonym: "poisonous agents" RELATED [ChEBI] synonym: "poisonous substance" RELATED [ChEBI] synonym: "poisonous substances" RELATED [ChEBI] synonym: "poisons" RELATED [ChEBI] synonym: "toxic agent" RELATED [ChEBI] synonym: "toxic agents" RELATED [ChEBI] synonym: "toxic substance" RELATED [ChEBI] synonym: "toxic substances" RELATED [ChEBI] xref: Wikipedia:Poison is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:65212 name: polysaccharide derivative namespace: chebi_ontology def: "A carbohydrate derivative that is any derivative of a polysaccharide." [] subset: 3_STAR synonym: "polysaccharide derivatives" RELATED [ChEBI] is_a: CHEBI:167559 ! glycan is_a: CHEBI:33694 ! biomacromolecule is_a: CHEBI:63299 ! carbohydrate derivative relationship: has_functional_parent CHEBI:18154 ! polysaccharide [Term] id: CHEBI:65255 name: food preservative namespace: chebi_ontology def: "Substances which are added to food in order to prevent decomposition caused by microbial growth or by undesirable chemical changes." [] subset: 3_STAR synonym: "food preservatives" RELATED [ChEBI] is_a: CHEBI:64047 ! food additive [Term] id: CHEBI:65256 name: antimicrobial food preservative namespace: chebi_ontology def: "A food preservative which prevents decomposition of food by preventing the growth of fungi or bacteria. In European countries, E-numbers for permitted food preservatives are from E200 to E299, divided into sorbates (E200-209), benzoates (E210-219), sulfites (E220-229), phenols and formates (E230-239), nitrates (E240-259), acetates (E260-269), lactates (E270-279), propionates (E280-289) and others (E290-299)." [] subset: 3_STAR synonym: "antimicrobial food preservatives" RELATED [ChEBI] synonym: "antimicrobial preservative" RELATED [ChEBI] synonym: "antimicrobial preservatives" RELATED [ChEBI] is_a: CHEBI:33281 ! antimicrobial agent is_a: CHEBI:65255 ! food preservative [Term] id: CHEBI:65296 name: primary ammonium ion namespace: chebi_ontology def: "An ammonium ion derivative resulting from the protonation of the nitrogen atom of a primary amino compound. Major species at pH 7.3." [] subset: 3_STAR synonym: "a primary amine" RELATED [UniProt] synonym: "substituted ammonium" RELATED [ChEBI] is_a: CHEBI:25697 ! organic cation is_a: CHEBI:35274 ! ammonium ion derivative relationship: is_conjugate_acid_of CHEBI:50994 ! primary amino compound property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "H3NR" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "17.031" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "17.02655" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[NH3+][*]" xsd:string [Term] id: CHEBI:67079 name: anti-inflammatory agent namespace: chebi_ontology def: "Any compound that has anti-inflammatory effects." [] subset: 3_STAR synonym: "anti-inflammatory agents" RELATED [ChEBI] synonym: "antiinflammatory agent" RELATED [ChEBI] synonym: "antiinflammatory agents" RELATED [ChEBI] is_a: CHEBI:33232 ! application [Term] id: CHEBI:72587 name: (R)-noradrenaline(1+) namespace: chebi_ontology def: "An organic cation that is the conjugate acid of (R)-noradrenaline, obtained by protonation of the priamry amino group; major species at pH 7.3." [] subset: 3_STAR synonym: "(2R)-2-(3,4-dihydroxyphenyl)-2-hydroxyethanaminium" EXACT IUPAC_NAME [IUPAC] synonym: "(R)-noradrenaline" RELATED [UniProt] synonym: "(R)-noradrenaline cation" RELATED [ChEBI] synonym: "(R)-noradrenalinium cation" RELATED [ChEBI] synonym: "(R)-noradrenalinium(1+)" RELATED [ChEBI] xref: PDBeChem:E5E is_a: CHEBI:166902 ! noradrenaline(1+) relationship: has_role CHEBI:77746 ! human metabolite relationship: is_conjugate_acid_of CHEBI:18357 ! (R)-noradrenaline property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C8H12NO3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/p+1/t8-/m0/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "SFLSHLFXELFNJZ-QMMMGPOBSA-O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "170.187" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "170.08117" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "C=1(C=CC(=CC1O)[C@H](C[NH3+])O)O" xsd:string [Term] id: CHEBI:72695 name: organic molecule namespace: chebi_ontology def: "Any molecule that consists of at least one carbon atom as part of the electrically neutral entity." [] subset: 3_STAR synonym: "organic compound" RELATED [ChEBI] synonym: "organic compounds" RELATED [ChEBI] synonym: "organic molecules" RELATED [ChEBI] is_a: CHEBI:25367 ! molecule is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:72813 name: exopolysaccharide namespace: chebi_ontology def: "A biomacromolecule composed of carbohydrate residues which is secreted by a microorganism into the surrounding environment." [] subset: 3_STAR synonym: "exopolysaccharides" RELATED [ChEBI] synonym: "extracellular polymeric substance" RELATED [ChEBI] synonym: "extracellular polymeric substances" RELATED [ChEBI] xref: MetaCyc:Exopolysaccharides xref: PMID:11160795 {source="Europe PMC"} xref: PMID:11785425 {source="Europe PMC"} xref: PMID:1444258 {source="Europe PMC"} xref: PMID:15738217 {source="Europe PMC"} xref: PMID:16075348 {source="Europe PMC"} xref: PMID:17440912 {source="Europe PMC"} xref: PMID:18097339 {source="Europe PMC"} xref: PMID:19453747 {source="Europe PMC"} xref: PMID:20172021 {source="Europe PMC"} xref: PMID:20631870 {source="Europe PMC"} xref: PMID:20718297 {source="Europe PMC"} xref: PMID:2688547 {source="Europe PMC"} xref: PMID:6354590 {source="Europe PMC"} xref: Wikipedia:Exopolysaccharide xref: Wikipedia:Extracellular_polymeric_substance is_a: CHEBI:33694 ! biomacromolecule [Term] id: CHEBI:73336 name: vulnerary namespace: chebi_ontology def: "A drug used in treating and healing of wounds." [] subset: 3_STAR synonym: "vulneraries" RELATED [ChEBI] synonym: "wound-healing agent" RELATED [ChEBI] synonym: "wound-healing agents" RELATED [ChEBI] synonym: "wound-healing drug" RELATED [ChEBI] synonym: "wound-healing drugs" RELATED [ChEBI] xref: Wikipedia:Wound_healing is_a: CHEBI:23888 ! drug [Term] id: CHEBI:73398 name: indole skeleton namespace: chebi_ontology def: "A mancude heterobicyclic organic group consisting of a benzene ring fused to a pyrrole ring." [] subset: 3_STAR is_a: CHEBI:73541 ! organic heterobicyclic ring property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C8N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "110.09230" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "110.00307" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "C1(=C(C(=C2C(=C1*)N(C(=C2*)*)*)*)*)*" xsd:string [Term] id: CHEBI:73541 name: organic heterobicyclic ring namespace: chebi_ontology def: "A bicyclic organic group that contains both carbon and hetero atoms." [] subset: 3_STAR synonym: "organic heterobicyclic rings" RELATED [ChEBI] is_a: CHEBI:52845 ! cyclic organic group [Term] id: CHEBI:75763 name: eukaryotic metabolite namespace: chebi_ontology def: "Any metabolite produced during a metabolic reaction in eukaryotes, the taxon that include members of the fungi, plantae and animalia kingdoms." [] subset: 3_STAR synonym: "eukaryotic metabolites" RELATED [ChEBI] is_a: CHEBI:25212 ! metabolite [Term] id: CHEBI:75767 name: animal metabolite namespace: chebi_ontology alt_id: CHEBI:77721 alt_id: CHEBI:77743 def: "Any eukaryotic metabolite produced during a metabolic reaction in animals that include diverse creatures from sponges, insects to mammals." [] subset: 3_STAR synonym: "animal metabolites" RELATED [ChEBI] is_a: CHEBI:75763 ! eukaryotic metabolite [Term] id: CHEBI:75768 name: mammalian metabolite namespace: chebi_ontology alt_id: CHEBI:77464 alt_id: CHEBI:77744 def: "Any animal metabolite produced during a metabolic reaction in mammals." [] subset: 3_STAR synonym: "mammalian metabolites" RELATED [ChEBI] is_a: CHEBI:75767 ! animal metabolite [Term] id: CHEBI:75771 name: mouse metabolite namespace: chebi_ontology def: "Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus)." [] subset: 3_STAR synonym: "mouse metabolites" RELATED [ChEBI] synonym: "Mus musculus metabolite" RELATED [ChEBI] synonym: "Mus musculus metabolites" RELATED [ChEBI] is_a: CHEBI:75768 ! mammalian metabolite [Term] id: CHEBI:75772 name: Saccharomyces cerevisiae metabolite namespace: chebi_ontology alt_id: CHEBI:76949 alt_id: CHEBI:76951 def: "Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae)." [] subset: 3_STAR synonym: "baker's yeast metabolite" RELATED [ChEBI] synonym: "baker's yeast metabolites" RELATED [ChEBI] synonym: "baker's yeast secondary metabolite" RELATED [ChEBI] synonym: "baker's yeast secondary metabolites" RELATED [ChEBI] synonym: "S. cerevisiae metabolite" RELATED [ChEBI] synonym: "S. cerevisiae metabolites" RELATED [ChEBI] synonym: "S. cerevisiae secondary metabolite" RELATED [ChEBI] synonym: "S. cerevisiae secondary metabolites" RELATED [ChEBI] synonym: "Saccharomyces cerevisiae metabolites" RELATED [ChEBI] synonym: "Saccharomyces cerevisiae secondary metabolites" RELATED [ChEBI] is_a: CHEBI:76946 ! fungal metabolite [Term] id: CHEBI:75787 name: prokaryotic metabolite namespace: chebi_ontology def: "Any metabolite produced during a metabolic reaction in prokaryotes, the taxon that include members of domains such as the bacteria and archaea." [] subset: 3_STAR synonym: "prokaryotic metabolites" RELATED [ChEBI] is_a: CHEBI:25212 ! metabolite [Term] id: CHEBI:76206 name: xenobiotic metabolite namespace: chebi_ontology def: "Any metabolite produced by metabolism of a xenobiotic compound." [] subset: 3_STAR synonym: "xenobiotic metabolites" RELATED [ChEBI] is_a: CHEBI:25212 ! metabolite [Term] id: CHEBI:76759 name: EC 3.* (hydrolase) inhibitor namespace: chebi_ontology def: "Any enzyme inhibitor that interferes with the action of a hydrolase (EC 3.*.*.*)." [] subset: 3_STAR synonym: "EC 3.* (hydrolase) inhibitors" RELATED [ChEBI] synonym: "EC 3.* inhibitor" RELATED [ChEBI] synonym: "EC 3.* inhibitors" RELATED [ChEBI] synonym: "EC 3.*.*.* inhibitor" RELATED [ChEBI] synonym: "EC 3.*.*.* inhibitors" RELATED [ChEBI] synonym: "hydrolase (EC 3.*) inhibitor" RELATED [ChEBI] synonym: "hydrolase (EC 3.*) inhibitors" RELATED [ChEBI] synonym: "hydrolase inhibitor" RELATED [ChEBI] synonym: "hydrolase inhibitors" RELATED [ChEBI] xref: Wikipedia:Hydrolase is_a: CHEBI:23924 ! enzyme inhibitor [Term] id: CHEBI:76764 name: EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor namespace: chebi_ontology def: "Any hydrolase inhibitor that interferes with the action of a hydrolase acting on C-N bonds, other than peptide bonds (EC 3.5.*.*)." [] subset: 3_STAR synonym: "EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitor" RELATED [ChEBI] synonym: "EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitors" RELATED [ChEBI] synonym: "EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitor" RELATED [ChEBI] synonym: "EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitors" RELATED [ChEBI] synonym: "EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitors" RELATED [ChEBI] synonym: "EC 3.5.* inhibitor" RELATED [ChEBI] synonym: "EC 3.5.* inhibitors" RELATED [ChEBI] is_a: CHEBI:76759 ! EC 3.* (hydrolase) inhibitor [Term] id: CHEBI:76807 name: EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor namespace: chebi_ontology def: "An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide linear amide C-N hydrolase (EC 3.5.1.*)." [] subset: 3_STAR synonym: "EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitors" RELATED [ChEBI] synonym: "EC 3.5.1.* inhibitor" RELATED [ChEBI] synonym: "EC 3.5.1.* inhibitors" RELATED [ChEBI] synonym: "non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitor" RELATED [ChEBI] synonym: "non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitors" RELATED [ChEBI] is_a: CHEBI:76764 ! EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor [Term] id: CHEBI:76924 name: plant metabolite namespace: chebi_ontology alt_id: CHEBI:75766 alt_id: CHEBI:76925 def: "Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms." [] subset: 3_STAR synonym: "plant metabolites" RELATED [ChEBI] synonym: "plant secondary metabolites" RELATED [ChEBI] is_a: CHEBI:75763 ! eukaryotic metabolite [Term] id: CHEBI:76946 name: fungal metabolite namespace: chebi_ontology alt_id: CHEBI:75765 alt_id: CHEBI:76947 def: "Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds." [] subset: 3_STAR synonym: "fungal metabolites" RELATED [ChEBI] is_a: CHEBI:75763 ! eukaryotic metabolite [Term] id: CHEBI:76967 name: human xenobiotic metabolite namespace: chebi_ontology def: "Any human metabolite produced by metabolism of a xenobiotic compound in humans." [] subset: 3_STAR synonym: "human xenobiotic metabolites" RELATED [ChEBI] is_a: CHEBI:76206 ! xenobiotic metabolite is_a: CHEBI:77746 ! human metabolite [Term] id: CHEBI:76969 name: bacterial metabolite namespace: chebi_ontology alt_id: CHEBI:75760 alt_id: CHEBI:76970 def: "Any prokaryotic metabolite produced during a metabolic reaction in bacteria." [] subset: 3_STAR is_a: CHEBI:75787 ! prokaryotic metabolite [Term] id: CHEBI:76971 name: Escherichia coli metabolite namespace: chebi_ontology def: "Any bacterial metabolite produced during a metabolic reaction in Escherichia coli." [] subset: 3_STAR synonym: "E.coli metabolite" RELATED [ChEBI] synonym: "E.coli metabolites" RELATED [ChEBI] synonym: "Escherichia coli metabolites" RELATED [ChEBI] is_a: CHEBI:76969 ! bacterial metabolite [Term] id: CHEBI:77746 name: human metabolite namespace: chebi_ontology alt_id: CHEBI:75770 alt_id: CHEBI:77123 def: "Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens)." [] subset: 3_STAR synonym: "H. sapiens metabolite" RELATED [ChEBI] synonym: "H. sapiens metabolites" RELATED [ChEBI] synonym: "Homo sapiens metabolite" RELATED [ChEBI] synonym: "Homo sapiens metabolites" RELATED [ChEBI] is_a: CHEBI:75768 ! mammalian metabolite [Term] id: CHEBI:77941 name: EC 3.5.1.4 (amidase) inhibitor namespace: chebi_ontology def: "An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of amidase (EC 3.5.1.4)." [] subset: 3_STAR synonym: "acylamidase inhibitor" RELATED [ChEBI] synonym: "acylamidase inhibitors" RELATED [ChEBI] synonym: "acylamide amidohydrolase inhibitor" RELATED [ChEBI] synonym: "acylamide amidohydrolase inhibitors" RELATED [ChEBI] synonym: "amidase (EC 3.5.1.4) inhibitor" RELATED [ChEBI] synonym: "amidase (EC 3.5.1.4) inhibitors" RELATED [ChEBI] synonym: "amidase inhibitor" RELATED [ChEBI] synonym: "amidase inhibitors" RELATED [ChEBI] synonym: "amidohydrolase inhibitor" RELATED [ChEBI] synonym: "amidohydrolase inhibitors" RELATED [ChEBI] synonym: "deaminase inhibitor" RELATED [ChEBI] synonym: "deaminase inhibitors" RELATED [ChEBI] synonym: "EC 3.5.1.4 (amidase) inhibitors" RELATED [ChEBI] synonym: "EC 3.5.1.4 inhibitor" RELATED [ChEBI] synonym: "EC 3.5.1.4 inhibitors" RELATED [ChEBI] synonym: "fatty acylamidase inhibitor" RELATED [ChEBI] synonym: "fatty acylamidase inhibitors" RELATED [ChEBI] synonym: "N-acetylaminohydrolase inhibitor" RELATED [ChEBI] synonym: "N-acetylaminohydrolase inhibitors" RELATED [ChEBI] xref: Wikipedia:Amidase is_a: CHEBI:76807 ! EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor [Term] id: CHEBI:77974 name: food packaging gas namespace: chebi_ontology def: "A food additive that is a (generally inert) gas which is used to envelop foodstuffs during packing and so protect them from unwanted chemical reactions such as food spoilage or oxidation during subsequent transport and storage. The term includes propellant gases, used to expel foods from a container." [] subset: 3_STAR synonym: "food packaging gases" RELATED [ChEBI] xref: Wikipedia:Packaging_gas is_a: CHEBI:64047 ! food additive [Term] id: CHEBI:78295 name: food component namespace: chebi_ontology def: "A physiological role played by any substance that is distributed in foodstuffs. It includes materials derived from plants or animals, such as vitamins or minerals, as well as environmental contaminants." [] subset: 3_STAR synonym: "dietary component" RELATED [ChEBI] synonym: "dietary components" RELATED [ChEBI] synonym: "food components" RELATED [ChEBI] is_a: CHEBI:52211 ! physiological role [Term] id: CHEBI:78433 name: refrigerant namespace: chebi_ontology def: "A substance used in a thermodynamic heat pump cycle or refrigeration cycle that undergoes a phase change from a gas to a liquid and back. Refrigerants are used in air-conditioning systems and freezers or refrigerators and are assigned a \"R\" number (by ASHRAE - formerly the American Society of Heating, Refrigerating and Air Conditioning Engineers), which is determined systematically according to their molecular structure." [] subset: 3_STAR synonym: "refrigerants" RELATED [ChEBI] xref: Wikipedia:Refrigerant is_a: CHEBI:33232 ! application [Term] id: CHEBI:78608 name: alpha-amino acid zwitterion namespace: chebi_ontology alt_id: CHEBI:83409 def: "An amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of any alpha-amino acid; major species at pH 7.3." [] subset: 3_STAR synonym: "an alpha-amino acid" RELATED [UniProt] xref: MetaCyc:Alpha-Amino-Acids {source="SUBMITTER"} is_a: CHEBI:35238 ! amino acid zwitterion relationship: is_tautomer_of CHEBI:33704 ! alpha-amino acid property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H4NO2R" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "74.059" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "74.02420" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[NH3+]C([*])C([O-])=O" xsd:string [Term] id: CHEBI:78616 name: carbohydrates and carbohydrate derivatives namespace: chebi_ontology def: "Any organooxygen compound that is a polyhydroxy-aldehyde or -ketone, or a compound derived from one. Carbohydrates contain only carbon, hydrogen and oxygen and usually have an empirical formula Cm(H2O)n; carbohydrate derivatives may contain other elements by substitution or condensation." [] subset: 3_STAR synonym: "carbohydrates and derivatives" RELATED [ChEBI] synonym: "carbohydrates and their derivatives" RELATED [ChEBI] is_a: CHEBI:36963 ! organooxygen compound [Term] id: CHEBI:78675 name: fundamental metabolite namespace: chebi_ontology def: "Any metabolite produced by all living cells." [] subset: 3_STAR synonym: "essential metabolite" RELATED [ChEBI] synonym: "essential metabolites" RELATED [ChEBI] synonym: "fundamental metabolites" RELATED [ChEBI] is_a: CHEBI:25212 ! metabolite [Term] id: CHEBI:79387 name: trivalent inorganic anion namespace: chebi_ontology def: "Any inorganic anion with a valency of three." [] subset: 3_STAR synonym: "trivalent inorganic anions" RELATED [ChEBI] is_a: CHEBI:24834 ! inorganic anion [Term] id: CHEBI:79388 name: divalent inorganic anion namespace: chebi_ontology def: "Any inorganic anion with a valency of two." [] subset: 3_STAR synonym: "divalent inorganic anions" RELATED [ChEBI] is_a: CHEBI:24834 ! inorganic anion [Term] id: CHEBI:79389 name: monovalent inorganic anion namespace: chebi_ontology def: "Any inorganic anion with a valency of one." [] subset: 3_STAR synonym: "monovalent inorganic anions" RELATED [ChEBI] is_a: CHEBI:24834 ! inorganic anion [Term] id: CHEBI:83039 name: crustacean metabolite namespace: chebi_ontology def: "An animal metabolite produced by arthropods such as crabs, lobsters, crayfish, shrimps and krill." [] subset: 3_STAR synonym: "crustacean metabolites" RELATED [ChEBI] is_a: CHEBI:75767 ! animal metabolite [Term] id: CHEBI:83056 name: Daphnia magna metabolite namespace: chebi_ontology def: "A Daphnia metabolite produced by the species Daphnia magna." [] subset: 3_STAR synonym: "Daphnia magna metabolites" RELATED [ChEBI] is_a: CHEBI:83057 ! Daphnia metabolite [Term] id: CHEBI:83057 name: Daphnia metabolite namespace: chebi_ontology def: "A crustacean metabolite produced by the genus of small planktonic arthropods, Daphnia" [] subset: 3_STAR synonym: "Daphnia metabolites" RELATED [ChEBI] xref: Wikipedia:Daphnia is_a: CHEBI:83039 ! crustacean metabolite [Term] id: CHEBI:84729 name: hydroxyindoles namespace: chebi_ontology def: "Any member of the class of indoles carrying at least one hydroxy group." [] subset: 3_STAR is_a: CHEBI:24828 ! indoles is_a: CHEBI:33822 ! organic hydroxy compound [Term] id: CHEBI:84735 name: algal metabolite namespace: chebi_ontology def: "Any eukaryotic metabolite produced during a metabolic reaction in algae including unicellular organisms like chlorella and diatoms to multicellular organisms like giant kelps and brown algae." [] subset: 3_STAR synonym: "algal metabolites" RELATED [ChEBI] is_a: CHEBI:75763 ! eukaryotic metabolite [Term] id: CL:0000000 name: cell namespace: cell def: "A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane." [CARO:mah] comment: The definition of cell is intended to represent all cells, and thus a cell is defined as a material entity and not an anatomical structure, which implies that it is part of an organism (or the entirety of one). subset: cellxgene_subset subset: ubprop:upper_level xref: CALOHA:TS-2035 xref: FBbt:00007002 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:68646 xref: GO:0005623 xref: KUPO:0000002 xref: MESH:D002477 xref: VHOG:0001533 xref: WBbt:0004017 xref: XAO:0003012 xref: ZFA:0009000 {sssom:mapping_justification="vocab:UnspecifiedMatching"} is_a: UBERON:0000061 ! anatomical structure disjoint_from: GO:0031012 ! extracellular matrix disjoint_from: GO:0032991 ! protein-containing complex disjoint_from: GO:0043226 ! organelle relationship: has_part GO:0005634 {gci_filler="PATO:0001407", gci_relation="has_characteristic"} ! nucleus relationship: has_part GO:0005634 {gci_filler="PATO:0001908", gci_relation="has_characteristic"} ! nucleus relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: only_in_taxon NCBITaxon:131567 ! cellular organisms property_value: editor_note "CL and GO definitions of cell differ based on inclusive or exclusive of cell wall, etc." xsd:string property_value: editor_note "We struggled with this definition. We are worried about circularity. We also considered requiring the capability of metabolism." xsd:string [Term] id: CL:0000005 name: fibroblast neural crest derived def: "Any fibroblast that is deriived from the neural crest." [https://orcid.org/0000-0001-5208-3432] is_a: CL:0000057 ! fibroblast is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: CL:0000057 ! fibroblast intersection_of: develops_from CL:0000333 ! migratory neural crest cell relationship: develops_from CL:0000008 ! migratory cranial neural crest cell [Term] id: CL:0000006 name: neuronal receptor cell subset: cellxgene_subset synonym: "neuronal receptor cell (sensu Animalia)" EXACT [] is_a: CL:0000101 ! sensory neuron is_a: CL:0000197 ! sensory receptor cell intersection_of: CL:0000197 ! sensory receptor cell intersection_of: CL:0000540 ! neuron intersection_of: capable_of GO:0050906 ! detection of stimulus involved in sensory perception [Term] id: CL:0000007 name: early embryonic cell (metazoa) def: "A cell found in the embryo before the formation of all the gem layers is complete." [GOC:tfm] is_a: CL:0002321 ! embryonic cell (metazoa) [Term] id: CL:0000008 name: migratory cranial neural crest cell def: "Cell that is part of the migratory cranial neural crest population. Migratory cranial neural crest cells develop from premigratory cranial neural crest cells and have undergone epithelial to mesenchymal transition and delamination." [https://orcid.org/0000-0001-5208-3432, ZFA:0007091] is_a: CL:0000333 ! migratory neural crest cell [Term] id: CL:0000011 name: migratory trunk neural crest cell def: "Cell that is part of the migratory trunk neural crest population. Migratory trunk neural crest cells develop from premigratory trunk neural crest cells and have undergone epithelial to mesenchymal transition and delamination." [https://orcid.org/0000-0001-5208-3432, ZFA:0007095] is_a: CL:0000333 ! migratory neural crest cell [Term] id: CL:0000014 name: germ line stem cell def: "A stem cell that is the precursor of gametes." [doi:10.1016/j.stem.2012.05.016] synonym: "germline stem cell" EXACT [] xref: FBbt:00004861 is_a: CL:0000034 {is_inferred="true"} ! stem cell is_a: CL:0000039 ! germ line cell intersection_of: CL:0000039 ! germ line cell intersection_of: capable_of GO:0017145 ! stem cell division [Term] id: CL:0000015 name: male germ cell def: "A germ cell that supports male gamete production. In some species, non-germ cells known as Sertoli cells also play a role in spermatogenesis." [https://orcid.org/0000-0001-5208-3432, PMID:29462262] subset: cellxgene_subset xref: FMA:72290 xref: MA:0002765 xref: ncithesaurus:Spermatogenic_Cell xref: VHOG:0001531 is_a: CL:0000586 {is_inferred="true"} ! germ cell relationship: capable_of_part_of GO:0007283 ! spermatogenesis property_value: seeAlso "https://github.com/obophenotype/cell-ontology/issues/574" xsd:string [Term] id: CL:0000017 name: spermatocyte def: "A male germ cell that develops from spermatogonia. The euploid primary spermatocytes undergo meiosis and give rise to the haploid secondary spermatocytes which in turn give rise to spermatids." [GOC:tfm, MESH:D013090] xref: BTO:0001275 xref: CALOHA:TS-0951 xref: EMAPA:31484 xref: FBbt:00004936 xref: FMA:84049 xref: WBbt:0006799 is_a: CL:0000015 ! male germ cell intersection_of: CL:0000015 ! male germ cell intersection_of: capable_of GO:0048137 ! spermatocyte division relationship: capable_of GO:0048137 ! spermatocyte division relationship: develops_from CL:0000020 ! spermatogonium [Term] id: CL:0000018 name: spermatid def: "A male germ cell that develops from the haploid secondary spermatocytes. Without further division, spermatids undergo structural changes and give rise to spermatozoa." [MESH:D013087] synonym: "nematoblast" EXACT [] xref: BTO:0001274 xref: CALOHA:TS-0950 xref: EMAPA:31486 xref: FBbt:00004942 xref: FMA:72294 xref: WBbt:0006800 is_a: CL:0000015 ! male germ cell is_a: CL:0000255 ! eukaryotic cell is_a: CL:0000413 ! haploid cell intersection_of: CL:0000015 ! male germ cell intersection_of: capable_of GO:0001675 ! acrosome assembly intersection_of: capable_of GO:0007288 ! sperm axoneme assembly intersection_of: capable_of GO:0007289 ! spermatid nucleus differentiation intersection_of: has_characteristic PATO:0001375 ! haploid relationship: capable_of GO:0001675 ! acrosome assembly relationship: capable_of GO:0007288 ! sperm axoneme assembly relationship: capable_of GO:0007289 ! spermatid nucleus differentiation relationship: develops_from CL:0000657 ! secondary spermatocyte [Term] id: CL:0000019 name: sperm def: "A mature male germ cell that develops from a spermatid." [GOC:tfm, MESH:D013094] subset: cellxgene_subset synonym: "sperm cell" EXACT [] synonym: "spermatozoid" EXACT [] synonym: "spermatozoon" EXACT [] xref: BTO:0001277 xref: BTO:0002046 xref: CALOHA:TS-0949 xref: FBbt:00004954 xref: FMA:67338 xref: WBbt:0006798 is_a: CL:0000255 ! eukaryotic cell is_a: CL:0000408 {is_inferred="true"} ! male gamete relationship: develops_from CL:0000018 ! spermatid [Term] id: CL:0000020 name: spermatogonium def: "An euploid male germ cell of an early stage of spermatogenesis." [MESH:D013093] synonym: "spermatogonial cell" EXACT [] xref: BTO:0000958 xref: CALOHA:TS-2193 xref: EMAPA:31482 xref: FBbt:00004934 xref: FBbt:00004935 xref: FMA:72291 is_a: CL:0000015 ! male germ cell intersection_of: CL:0000015 ! male germ cell intersection_of: has_characteristic PATO:0001394 ! diploid intersection_of: has_characteristic PATO:0001501 ! immature relationship: has_characteristic PATO:0001394 ! diploid relationship: has_characteristic PATO:0001501 ! immature [Term] id: CL:0000021 name: female germ cell def: "Female germ cell is a germ cell that supports female gamete production." [GOC:tfm, PMID:11023867, PMID:20454446] subset: cellxgene_subset xref: MA:0000388 xref: ncithesaurus:Egg xref: VHOG:0001530 is_a: CL:0000255 ! eukaryotic cell is_a: CL:0000586 {is_inferred="true"} ! germ cell intersection_of: CL:0000586 ! germ cell intersection_of: capable_of GO:0048477 ! oogenesis relationship: capable_of GO:0048477 ! oogenesis [Term] id: CL:0000022 name: female germ line stem cell def: "A stem cell that is the precursor of female gametes." [doi:10.1016/j.stem.2012.05.016] xref: FBbt:00004873 is_a: CL:0000014 {is_inferred="true"} ! germ line stem cell is_a: CL:0000021 {is_inferred="true"} ! female germ cell intersection_of: CL:0000021 ! female germ cell intersection_of: capable_of GO:0017145 ! stem cell division [Term] id: CL:0000023 name: oocyte def: "A female germ cell that has entered meiosis." [GOC:tfm, ISBN:0721662544] subset: cellxgene_subset synonym: "oogonium" RELATED [] xref: BTO:0000964 xref: CALOHA:TS-0711 xref: FBbt:00004886 xref: FMA:18644 xref: MESH:D009865 xref: WBbt:0006797 is_a: CL:0000021 {is_inferred="true"} ! female germ cell relationship: only_in_taxon NCBITaxon:33208 ! Metazoa relationship: participates_in GO:0007143 ! female meiotic nuclear division [Term] id: CL:0000024 name: oogonial cell def: "An undifferentiated germ cell that proliferates rapidly and gives rise to oocytes." [GOC:tfm, ISBN:0721662544] subset: cellxgene_subset xref: FMA:83673 is_a: CL:0000021 {is_inferred="true"} ! female germ cell intersection_of: CL:0000021 ! female germ cell intersection_of: capable_of GO:0000278 ! mitotic cell cycle relationship: capable_of GO:0000278 ! mitotic cell cycle relationship: develops_from CL:0000670 ! primordial germ cell [Term] id: CL:0000025 name: egg cell def: "A female gamete where meiosis has progressed to metaphase II and is able to participate in fertilization." [GOC:tfm, ISBN:0721662544] synonym: "mature oocyte" EXACT [] synonym: "ovum" EXACT [] xref: BTO:0000369 xref: BTO:0003801 xref: CALOHA:TS-2191 xref: FBbt:00057012 xref: FMA:67343 xref: MESH:D010063 is_a: CL:0000675 {is_inferred="true"} ! female gamete relationship: develops_from CL:0000023 ! oocyte relationship: participates_in GO:0007143 ! female meiotic nuclear division property_value: depiction "https://www.swissbiopics.org/api/image/Egg_cell.svg" xsd:anyURI [Term] id: CL:0000027 name: smooth muscle cell neural crest derived def: "A smooth muscle cell derived from the neural crest." [https://orcid.org/0000-0001-5208-3432] is_a: CL:0000192 {is_inferred="true"} ! smooth muscle cell is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: CL:0000192 ! smooth muscle cell intersection_of: develops_from CL:0000333 ! migratory neural crest cell relationship: develops_from CL:0000008 ! migratory cranial neural crest cell [Term] id: CL:0000029 name: neural crest derived neuron synonym: "neuron neural crest derived" EXACT [] is_a: CL:0000540 {is_inferred="true"} ! neuron is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: CL:0000540 ! neuron intersection_of: develops_from CL:0000333 ! migratory neural crest cell relationship: develops_from CL:0002676 ! neural crest derived neuroblast [Term] id: CL:0000031 name: neuroblast (sensu Vertebrata) def: "A cell that will develop into a neuron often after a migration phase." [GOC:NV, http://en.wikipedia.org/wiki/Neuroblast] subset: cellxgene_subset synonym: "neuroblast" EXACT [] xref: BTO:0000930 xref: FMA:70563 is_a: CL:0000055 ! non-terminally differentiated cell is_a: CL:0000255 ! eukaryotic cell relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata [Term] id: CL:0000034 name: stem cell def: "A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [GOC:tfm, MESH:D013234] comment: This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’. subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "animal stem cell" EXACT [] xref: CALOHA:TS-2086 xref: FMA:63368 is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011115 ! precursor cell intersection_of: CL:0000000 ! cell intersection_of: capable_of GO:0017145 ! stem cell division relationship: capable_of GO:0017145 ! stem cell division relationship: in_taxon NCBITaxon:33208 ! Metazoa property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000035 name: single fate stem cell def: "A stem cell that self-renews as well as give rise to a single mature cell type." [GOC:tfm] synonym: "unipotent stem cell" EXACT [] synonym: "unipotential stem cell" EXACT [] xref: FMA:70569 is_a: CL:0000723 ! somatic stem cell intersection_of: CL:0000000 ! cell intersection_of: capable_of GO:0017145 ! stem cell division intersection_of: has_characteristic PATO:0001400 ! unipotent relationship: has_characteristic PATO:0001400 ! unipotent [Term] id: CL:0000037 name: hematopoietic stem cell def: "A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. Hematopoietic stem cells lack cell markers of effector cells (lin-negative). Lin-negative is defined by lacking one or more of the following cell surface markers: CD2, CD3 epsilon, CD4, CD5 ,CD8 alpha chain, CD11b, CD14, CD19, CD20, CD56, ly6G, ter119." [GOC:add, GOC:dsd, GOC:tfm, http://en.wikipedia.org/wiki/Hematopoietic_stem_cell, PMID:19022770] comment: Markers differ between species, and two sets of markers have been described for mice. HSCs are reportedly CD34-positive, CD45-positive, CD48-negative, CD150-positive, CD133-positive, and CD244-negative. subset: blood_and_immune_upper_slim subset: cellxgene_subset subset: human_reference_atlas synonym: "blood forming stem cell" EXACT [] synonym: "colony forming unit hematopoietic" RELATED [] synonym: "hemopoietic stem cell" EXACT [] synonym: "HSC" RELATED OMO:0003000 [] xref: BTO:0000725 xref: CALOHA:TS-0448 xref: FMA:86475 xref: MESH:D006412 xref: VHOG:0001485 is_a: CL:0000723 ! somatic stem cell is_a: CL:0008001 ! hematopoietic precursor cell is_a: CL:0011026 ! progenitor cell intersection_of: CL:0000988 ! hematopoietic cell intersection_of: capable_of GO:0002244 ! hematopoietic progenitor cell differentiation intersection_of: capable_of GO:0048103 ! somatic stem cell division intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G intersection_of: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) relationship: capable_of GO:0002244 ! hematopoietic progenitor cell differentiation relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G relationship: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) relationship: develops_from CL:0000566 ! angioblastic mesenchymal cell property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000038 name: erythroid progenitor cell def: "A progenitor cell committed to the erythroid lineage." [GOC:add, ISBN:0721601464] subset: blood_and_immune_upper_slim subset: cellxgene_subset synonym: "BFU-E" RELATED OMO:0003000 [] synonym: "blast forming unit erythroid" RELATED [] synonym: "burst forming unit erythroid" RELATED [] synonym: "CFU-E" RELATED OMO:0003000 [] synonym: "colony forming unit erythroid" RELATED [] synonym: "erythroid stem cell" RELATED [] xref: BTO:0004911 is_a: CL:0000764 ! erythroid lineage cell is_a: CL:0000839 {is_inferred="true"} ! myeloid lineage restricted progenitor cell relationship: develops_from CL:0000050 ! megakaryocyte-erythroid progenitor cell [Term] id: CL:0000039 name: germ line cell def: "A cell that is within the developmental lineage of gametes and is able to pass along its genetic material to offspring." [GOC:tfm, ISBN:0721662544] comment: Originally this term had some plant germ line cell children. subset: general_cell_types_upper_slim subset: ubprop:upper_level is_a: CL:0000000 ! cell relationship: capable_of GO:0022414 ! reproductive process [Term] id: CL:0000048 name: multi fate stem cell def: "A stem cell that can give rise to multiple lineages of cells." [GOC:add] synonym: "multi-fate stem cell" EXACT [] synonym: "multifate stem cell" EXACT [] synonym: "multipotent cell" EXACT [] synonym: "multipotent stem cell" EXACT [] xref: FMA:84789 is_a: CL:0000034 ! stem cell intersection_of: CL:0000000 ! cell intersection_of: capable_of GO:0017145 ! stem cell division intersection_of: has_characteristic PATO:0001402 ! multipotent relationship: has_characteristic PATO:0001402 ! multipotent [Term] id: CL:0000049 name: common myeloid progenitor def: "A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages." [GOC:add, ISBN:0878932437, MESH:D023461] comment: This cell type is intended to be compatible with any vertebrate common myeloid progenitor. For mammalian CMP known to be CD34-positive, please use the term 'common myeloid progenitor, CD34-positive' (CL_0001059). subset: cellxgene_subset subset: human_reference_atlas synonym: "CFU-GEMM" RELATED OMO:0003000 [ISBN:0878932437] synonym: "CFU-S" RELATED OMO:0003000 [ISBN:0878932437] synonym: "CMP" RELATED OMO:0003000 [ISBN:0878932437] synonym: "colony forming unit granulocyte, erythrocyte, macrophage, and megakaryocyte" RELATED [ISBN:0878932437] synonym: "common myeloid precursor" EXACT [] synonym: "multipotential myeloid stem cell" RELATED [ISBN:0878932437] synonym: "myeloid stem cell" RELATED [ISBN:0878932437] synonym: "pluripotent stem cell (bone marrow)" RELATED [ISBN:0878932437] xref: BTO:0004730 is_a: CL:0002032 {is_inferred="true"} ! hematopoietic oligopotent progenitor cell disjoint_from: CL:0000050 ! megakaryocyte-erythroid progenitor cell disjoint_from: CL:0000051 ! common lymphoid progenitor property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000050 name: megakaryocyte-erythroid progenitor cell def: "A progenitor cell committed to the megakaryocyte and erythroid lineages." [GOC:add, GOC:dsd, GOC:tfm, http://en.wikipedia.org/wiki/Megakaryocyte-erythroid_progenitor_cell, MESH:D055015, PMID:16647566] comment: MEPs are reportedly CD19-negative, CD34-negative, CD45RA-negative, CD110-positive, CD117-positive, and SCA1-negative and reportedly express the transcription factors GATA-1 and NF-E2. subset: cellxgene_subset subset: human_reference_atlas synonym: "CFU-EM" EXACT [] synonym: "CFU-MegE" EXACT [] synonym: "colony forming unit erythroid megakaryocyte" EXACT [] synonym: "Meg/E progenitor" EXACT [] synonym: "megakaryocyte/erythrocyte progenitor" EXACT [] synonym: "megakaryocyte/erythroid progenitor cell" EXACT [] synonym: "MEP" EXACT [] is_a: CL:0000763 ! myeloid cell is_a: CL:0002032 {is_inferred="true"} ! hematopoietic oligopotent progenitor cell is_a: CL:0011026 ! progenitor cell intersection_of: CL:0002032 ! hematopoietic oligopotent progenitor cell intersection_of: capable_of GO:0030218 ! erythrocyte differentiation intersection_of: capable_of GO:0030219 ! megakaryocyte differentiation relationship: capable_of GO:0030218 ! erythrocyte differentiation relationship: capable_of GO:0030219 ! megakaryocyte differentiation property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000051 name: common lymphoid progenitor def: "A oligopotent progenitor cell committed to the lymphoid lineage." [GOC:add, GOC:dsd, GOC:tfm, PMID:10407577, PMID:16551251] comment: CLP are CD7-positive, CD10-positive, CD19-negative, CD34-positive, CD45RA-positive, CD79a-negative, CD127-positive, AA4.1-positive, RAG-negative, Sca-1-low, sIgM-negative, sIgD-negative, TdT-negative, Vpre-B-negative, and pre-BCR-negative. Expression of transcription factors include E2A-positive, EBF-positive, Ikaros-negative, PU.1-negative, and Pax5-negative. subset: cellxgene_subset subset: human_reference_atlas synonym: "CLP" RELATED OMO:0003000 [] synonym: "committed lymphopoietic stem cell" RELATED [] synonym: "common lymphocyte precursor" EXACT [] synonym: "common lymphocyte progenitor" EXACT [] synonym: "common lymphoid precursor" EXACT [] synonym: "early lymphocyte progenitor" RELATED [] synonym: "ELP" RELATED OMO:0003000 [] synonym: "lymphoid stem cell" RELATED [] synonym: "lymphopoietic stem cell" RELATED [] is_a: CL:0002032 {is_inferred="true"} ! hematopoietic oligopotent progenitor cell is_a: CL:0011026 ! progenitor cell intersection_of: CL:0002032 ! hematopoietic oligopotent progenitor cell intersection_of: capable_of GO:0030098 ! lymphocyte differentiation relationship: capable_of GO:0030098 ! lymphocyte differentiation property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000052 name: totipotent stem cell def: "A stem cell from which all cells of the body can form." [GOC:add, GOC:tfm] synonym: "totipotential stem cell" EXACT [] xref: FMA:84790 xref: MESH:D039901 is_a: CL:0000723 ! somatic stem cell [Term] id: CL:0000055 name: non-terminally differentiated cell def: "A precursor cell with a limited number of potential fates." [SANBI:mhl] comment: define using PATO mulit-potent or oligopotent? subset: cellxgene_subset synonym: "blast cell" EXACT [] xref: BTO:0000125 xref: FMA:84782 is_a: CL:0011115 ! precursor cell [Term] id: CL:0000056 name: myoblast def: "A cell that is commited to differentiating into a muscle cell. Embryonic myoblasts develop from the mesoderm. They undergo proliferation, migrate to their various sites, and then differentiate into the appropriate form of myocytes. Myoblasts also occur as transient populations of cells in muscles undergoing repair." [GOC:tfm, MESH:D032446, PMID:21849021] xref: BTO:0000222 xref: CALOHA:TS-0650 xref: FBbt:00005083 xref: FMA:70335 xref: VHOG:0001529 is_a: CL:0000680 ! muscle precursor cell [Term] id: CL:0000057 name: fibroblast def: "A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped." [http://en.wikipedia.org/wiki/Fibroblast, ISBN:0517223651, MESH:D005347] comment: These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative. subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas xref: BTO:0000452 xref: CALOHA:TS-0362 xref: FMA:63877 xref: NCIT:C12482 xref: VHOG:0001482 is_a: CL:0002320 ! connective tissue cell relationship: develops_from CL:0000134 ! mesenchymal stem cell property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000058 name: chondroblast def: "Skeletogenic cell that is typically non-terminally differentiated, secretes an avascular, GAG rich matrix; is not buried in cartilage tissue matrix, retains the ability to divide, located adjacent to cartilage tissue (including within the perichondrium), and develops from prechondroblast (and thus prechondrogenic) cell." [GO_REF:0000034, GOC:tfm, ISBN:0618947256] synonym: "chrondoplast" EXACT [] xref: BTO:0003607 xref: FMA:66783 is_a: CL:0000055 ! non-terminally differentiated cell is_a: CL:0002320 ! connective tissue cell relationship: develops_from CL:0007009 ! prechondroblast relationship: produces UBERON:0002418 ! cartilage tissue [Term] id: CL:0000064 name: ciliated cell def: "A cell that has a filiform extrusion of the cell surface." [GOC:tfm] subset: cellxgene_subset xref: VHOG:0001532 xref: XAO:0000031 is_a: CL:0000255 ! eukaryotic cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000000 ! cell intersection_of: has_part GO:0005929 ! cilium relationship: has_part GO:0005929 ! cilium [Term] id: CL:0000066 name: epithelial cell def: "A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina." [FB:ma, GOC:tfm, MESH:D004847] subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "epitheliocyte" EXACT [] xref: BTO:0000414 xref: CALOHA:TS-2026 xref: CARO:0000077 xref: FBbt:00000124 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:66768 xref: WBbt:0003672 xref: ZFA:0009034 {sssom:mapping_justification="vocab:UnspecifiedMatching"} is_a: CL:0000255 ! eukaryotic cell disjoint_from: CL:0000738 ! leukocyte relationship: part_of UBERON:0000483 ! epithelium property_value: depiction "https://www.swissbiopics.org/api/image/Epithelial_cells.svg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000067 name: ciliated epithelial cell def: "An epithelial cell that has a cilia." [GOC:tfm] subset: cellxgene_subset xref: FMA:70605 is_a: CL:0000064 ! ciliated cell is_a: CL:0000066 ! epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: has_part GO:0005929 ! cilium [Term] id: CL:0000068 name: duct epithelial cell def: "An epithelial cell that is part of a duct." [https://orcid.org/0000-0001-5208-3432] subset: cellxgene_subset is_a: CL:0000066 ! epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0000058 ! duct relationship: part_of UBERON:0000058 ! duct [Term] id: CL:0000069 name: branched duct epithelial cell is_a: CL:0000068 ! duct epithelial cell [Term] id: CL:0000071 name: blood vessel endothelial cell def: "An endothelial cell that lines the vasculature." [GOC:tfm] subset: cellxgene_subset subset: human_reference_atlas synonym: "cuboidal endothelial cell of vascular tree" EXACT [] is_a: CL:0000076 {is_inferred="true"} ! squamous epithelial cell is_a: CL:0002139 ! endothelial cell of vascular tree intersection_of: CL:0000076 ! squamous epithelial cell intersection_of: part_of UBERON:0004638 ! blood vessel endothelium relationship: develops_from CL:0002546 ! embryonic blood vessel endothelial progenitor cell relationship: part_of UBERON:0004638 ! blood vessel endothelium property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000072 name: non-branched duct epithelial cell is_a: CL:0000068 ! duct epithelial cell is_a: CL:0002078 ! meso-epithelial cell [Term] id: CL:0000075 name: columnar/cuboidal epithelial cell def: "A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube." [GO:0002065, https://orcid.org/0000-0001-5208-3432] subset: cellxgene_subset subset: human_reference_atlas is_a: CL:0000066 ! epithelial cell property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000076 name: squamous epithelial cell subset: cellxgene_subset xref: CALOHA:TS-1249 is_a: CL:0000066 ! epithelial cell [Term] id: CL:0000077 name: mesothelial cell def: "A flattened epithelial cell of mesenchymal origin that lines the serous cavity." [GOC:tfm, ISBN:0721662544] subset: cellxgene_subset subset: human_reference_atlas synonym: "mesotheliocyte" EXACT [] xref: FMA:66773 is_a: CL:0000076 ! squamous epithelial cell is_a: CL:0000213 ! lining cell is_a: CL:0002078 ! meso-epithelial cell property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000080 name: circulating cell def: "A cell which moves among different tissues of the body, via blood, lymph, or other medium." [GOC:add] is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: part_of UBERON:0000179 ! haemolymphatic fluid relationship: part_of UBERON:0000179 ! haemolymphatic fluid [Term] id: CL:0000081 name: blood cell def: "A cell found predominately in the blood." [GOC:add, GOC:tfm] subset: cellxgene_subset subset: general_cell_types_upper_slim xref: FMA:62844 xref: MESH:D001773 is_a: CL:0000988 {is_inferred="true"} ! hematopoietic cell intersection_of: CL:0000988 ! hematopoietic cell intersection_of: capable_of GO:0008015 ! blood circulation relationship: capable_of GO:0008015 ! blood circulation [Term] id: CL:0000082 name: epithelial cell of lung def: "An epithelial cell of the lung." [https://orcid.org/0000-0001-5208-3432] subset: cellxgene_subset synonym: "lung epithelial cell" EXACT [] xref: BTO:0004299 is_a: CL:0000066 ! epithelial cell is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0002048 ! lung relationship: part_of UBERON:0000115 ! lung epithelium [Term] id: CL:0000083 name: epithelial cell of pancreas def: "An epithelial cell of the pancreas." [GOC:tfm] synonym: "pancreas epithelial cell" EXACT [] synonym: "pancreatic epithelial cell" EXACT [] xref: BTO:0000028 is_a: CL:0000066 ! epithelial cell is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0001264 ! pancreas relationship: develops_from CL:0000223 ! endodermal cell relationship: part_of UBERON:0001264 ! pancreas [Term] id: CL:0000084 name: T cell def: "A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex." [GOC:add, GOC:tfm, ISBN:0781735149] subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "immature T cell" RELATED [] synonym: "mature T cell" RELATED [] synonym: "T lymphocyte" EXACT [] synonym: "T-cell" EXACT [] synonym: "T-lymphocyte" EXACT [] xref: BTO:0000782 xref: CALOHA:TS-1001 xref: FMA:62870 xref: MESH:D013601 xref: VHOG:0001479 is_a: CL:0000542 {is_inferred="true"} ! lymphocyte intersection_of: CL:0000542 ! lymphocyte intersection_of: capable_of GO:0002456 ! T cell mediated immunity relationship: capable_of GO:0002456 ! T cell mediated immunity relationship: develops_from CL:0000827 ! pro-T cell property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000095 name: neuron associated cell subset: cellxgene_subset is_a: CL:0002319 ! neural cell is_a: UBERON:0004121 ! ectoderm-derived structure relationship: develops_from CL:0000133 ! neurectodermal cell [Term] id: CL:0000098 name: sensory epithelial cell def: "A specialized epithelial cell involved in sensory perception. Restricted to special sense organs of the olfactory, gustatory, and vestibulocochlear receptor systems; contain sensory cells surrounded by supportive, non-receptive cells." [GOC:tfm, ISBN:0517223651, ISBN:0721662544] comment: The term "neuroepithelial cell" is used to describe both this cell type and neurecto-epithelial cell (CL:0000710). synonym: "neuroepithelial cell" BROAD [] xref: BTO:0004301 is_a: CL:0000066 ! epithelial cell is_a: CL:0000197 ! sensory receptor cell intersection_of: CL:0000066 ! epithelial cell intersection_of: capable_of GO:0050906 ! detection of stimulus involved in sensory perception [Term] id: CL:0000099 name: interneuron def: "Most generally any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions." [GOC:tfm, MESH:D007395] subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0003811 xref: FBbt:00005125 xref: FMA:67313 xref: WBbt:0005113 is_a: CL:0000540 ! neuron property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000100 name: motor neuron def: "An efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes or inhibits movement." [MESH:D009046, PMID:16875686] subset: cellxgene_subset subset: human_reference_atlas synonym: "motoneuron" EXACT [] xref: BTO:0000312 xref: FBbt:00005123 xref: FMA:83617 xref: WBbt:0005409 is_a: CL:0000527 ! efferent neuron property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000101 name: sensory neuron def: "Any neuron having a sensory function; an afferent neuron conveying sensory impulses." [ISBN:0721662544] xref: BTO:0001037 xref: FBbt:00005124 xref: FMA:84649 xref: MESH:D011984 xref: WBbt:0005759 is_a: CL:0000526 ! afferent neuron intersection_of: CL:0000540 ! neuron intersection_of: capable_of GO:0050906 ! detection of stimulus involved in sensory perception relationship: capable_of GO:0050906 ! detection of stimulus involved in sensory perception [Term] id: CL:0000107 name: autonomic neuron def: "A neuron whose cell body is within an autonomic ganglion." [GOC:tfm] xref: FMA:80121 is_a: CL:2000032 ! peripheral nervous system neuron intersection_of: CL:0000540 ! neuron intersection_of: has_soma_location UBERON:0002410 ! autonomic nervous system relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata) relationship: has_soma_location UBERON:0002410 ! autonomic nervous system [Term] id: CL:0000108 name: cholinergic neuron def: "A neuron that uses acetylcholine as a vesicular neurotransmitter." [GOC:tfm] xref: BTO:0004902 xref: FBbt:00007173 xref: FMA:84796 xref: MESH:D059329 xref: WBbt:0006840 is_a: CL:0000151 ! secretory cell is_a: CL:0000540 ! neuron intersection_of: CL:0000540 ! neuron intersection_of: capable_of GO:0014055 ! acetylcholine secretion, neurotransmission relationship: capable_of GO:0014055 ! acetylcholine secretion, neurotransmission [Term] id: CL:0000113 name: mononuclear phagocyte def: "A vertebrate phagocyte with a single nucleus." [GOC:add, GOC:tfm, ISBN:0781735149] subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0001433 is_a: CL:0000518 {is_inferred="true"} ! phagocyte (sensu Vertebrata) is_a: CL:0000842 ! mononuclear cell intersection_of: CL:0000518 ! phagocyte (sensu Vertebrata) intersection_of: has_characteristic PATO:0001407 ! mononucleate property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000115 name: endothelial cell def: "An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm." [GOC:tfm, http://en.wikipedia.org/wiki/Endothelial_cell, https://sourceforge.net/tracker/?func=detail&atid=440764&aid=3364936&group_id=36855, MESH:D042783, PMID:21275341] comment: From FMA: 9.07.2001: Endothelial cell has always been classified as a kind of epithelial cell, specifically a squamous cell but that is not true. First, endothelial cell can either be squamous or cuboidal (e.g. high-endothelial cell) and secondly, it has different embryological derivation (mesodermal) than a true epithelial cell (ectodermal and endodermal). The basis for present classification is the fact that it comprises the outermost layer or lining of anatomical structures (location-based) but a better structural basis for the differentia is the cytoskeleton of the cell. Endothelial cell has vimentin filaments while an epithelial cell has keratin filaments. [Onard]. subset: cellxgene_subset subset: human_reference_atlas synonym: "endotheliocyte" EXACT [] xref: BTO:0001176 xref: CALOHA:TS-0278 xref: FMA:66772 is_a: CL:0000213 ! lining cell is_a: CL:0002078 ! meso-epithelial cell property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000117 name: CNS neuron (sensu Vertebrata) is_a: CL:0000540 ! neuron is_a: UBERON:0004121 ! ectoderm-derived structure relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata) relationship: part_of UBERON:0001017 ! central nervous system [Term] id: CL:0000125 name: glial cell def: "A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Guide neuronal migration during development, and exchange metabolites with neurons." [MESH:D009457] comment: Not all glial cells develop from glioblasts, with microglia developing from the mesoderm instead. See https://github.com/obophenotype/cell-ontology/issues/1571 subset: cellxgene_subset subset: general_cell_types_upper_slim synonym: "neuroglia" RELATED [] synonym: "neuroglial cell" EXACT [] xref: BTO:0002606 xref: CALOHA:TS-0415 xref: FBbt:00005144 xref: FMA:54536 is_a: CL:0000095 ! neuron associated cell [Term] id: CL:0000133 name: neurectodermal cell def: "Ectoderm destined to be nervous tissue." [GOC:tfm, ISBN:068340007X] synonym: "neurectoderm cell" EXACT [] is_a: CL:0000221 ! ectodermal cell [Term] id: CL:0000134 name: mesenchymal stem cell def: "A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. In humans, this cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs." [FB:ma, GOC:dsd, http://en.wikipedia.org/wiki/Mesenchymal_stem_cell, http://www.copewithcytokines.de/cope.cgi?key=mesenchymal%20stem%20cells, PMCID:PMC2613570, PMID:10102814, PMID:16923606, PMID:17986482, PMID:19960544] comment: Many but not all mesenchymal cells derive from the mesoderm. MSCs are reportedly CD3-negative, CD4-negative, CD5-negative, CD8-negative, CD11a-negative, CD11b-negative, CD14-negative, CD19-negative, CD29-positive, CD31-negative, CD34-negative, CD38-negative, CD40-negative, CD44-positive, CD45-negative, CD49-positive, CD54-positive, CD66b-negative, CD79a-negative, CD80-negative, CD102-positive, CD106-positive, CD117-positive, CD121a-positive, CD121b-positive, CD123-positive, CD124-positive, CD133-negative, CD146-positive, CD166-positive, CD271-positive, B220-negative, Gr1-negative, MHCI-positive, MHCII-negative, SSEA4-negative, sca1-positive, Ter119-negative, and glycophorin A-negative. Cultured MSCs are capable of producing stem cell factor, IL7, IL8, IL11, TGF-beta, cofilin, galectin-1, laminin-receptor 1, cyclophilin A, and MMP-2. subset: cellxgene_subset synonym: "BMSC" RELATED OMO:0003000 [] synonym: "bone marrow stromal cells" NARROW [] synonym: "CFU-F" RELATED OMO:0003000 [] synonym: "colony-forming unit-fibroblast" NARROW [] synonym: "marrow stromal cells" NARROW [PMID:11378515] synonym: "mesenchymal precursor cell" RELATED [] synonym: "mesenchymal progenitor cells" RELATED OMO:0003004 [MESH:D044982] synonym: "mesenchymal stem cell" RELATED [] synonym: "mesenchymal stromal cell" RELATED [] synonym: "mesenchymal stromal cells" RELATED OMO:0003004 [] synonym: "MSC" RELATED OMO:0003000 [PMID:11378515] synonym: "stem cells, mesenchymal" RELATED OMO:0003004 [MESH:D044982] xref: BTO:0002625 xref: BTO:0003298 xref: FMA:70546 is_a: CL:0000048 ! multi fate stem cell is_a: CL:0002320 {is_inferred="true"} ! connective tissue cell property_value: seeAlso "https://github.com/obophenotype/cell-ontology/issues/474" xsd:string [Term] id: CL:0000136 name: adipocyte def: "A fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals. Fat is usually stored in the form of triglycerides." [MESH:D017667] subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "adipose cell" EXACT [] synonym: "fat cell" EXACT [] xref: BTO:0000443 xref: CALOHA:TS-0012 xref: FMA:63880 is_a: CL:0000325 ! stuff accumulating cell is_a: CL:0002320 ! connective tissue cell relationship: develops_from CL:0000134 ! mesenchymal stem cell property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000138 name: chondrocyte def: "Skeletogenic cell that is terminally differentiated, secretes an avascular, GAG-rich matrix, is embedded in cartilage tissue matrix, retains the ability to divide, and develops from a chondroblast cell." [GO_REF:0000034, MESH:D019902] subset: cellxgene_subset synonym: "cartilage cell" EXACT [] xref: BTO:0000249 xref: CALOHA:TS-0138 xref: FMA:66782 is_a: CL:0000153 ! glycosaminoglycan secreting cell is_a: CL:0000667 ! collagen secreting cell relationship: develops_from CL:0000058 ! chondroblast relationship: located_in UBERON:0002418 ! cartilage tissue [Term] id: CL:0000145 name: professional antigen presenting cell def: "A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response." [GOC:add, ISBN:0781735149] comment: Note change of name; nearly all somatic cells can present antigens to T cells via MHC Class I complexes leading to effector responses, but professional antigen presenting cells constitutively express MHC Class II as well as costimulatory molecules, and thus can initiate immune responses via T cells. subset: blood_and_immune_upper_slim subset: cellxgene_subset synonym: "APC" RELATED OMO:0003000 [] is_a: CL:0000738 ! leukocyte intersection_of: CL:0000738 ! leukocyte intersection_of: capable_of GO:0002504 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II relationship: capable_of GO:0002504 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [Term] id: CL:0000147 name: pigment cell def: "A pigment cell is a cell that contains pigment granules." [GOC:tfm] synonym: "chromatocyte" EXACT [] synonym: "chromatophore" EXACT [] xref: VHOG:0001678 is_a: CL:0000325 ! stuff accumulating cell [Term] id: CL:0000149 name: visual pigment cell synonym: "pigment cell" BROAD [] is_a: CL:0000147 ! pigment cell [Term] id: CL:0000150 name: glandular epithelial cell name: glandular secretory epithelial cell def: "A specialized epithelial cell that is capable of synthesizing and secreting certain biomolecules." [GOC:tfm] def: "An epithelial cell, located in a gland, that is specialised for the synthesis and secretion of specific biomolecules, such as hormones, or mucous." [GOC:tfm, ORCID:0000-0002-7073-9172] subset: cellxgene_subset synonym: "glandular epithelial cell" EXACT [] xref: CALOHA:TS-2085 xref: FMA:86494 is_a: CL:1100001 ! secretory epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: CL:0000151 ! secretory cell intersection_of: part_of UBERON:0002530 ! gland relationship: part_of UBERON:0002530 ! gland relationship: part_of UBERON:0006799 ! glandular epithelium [Term] id: CL:0000151 name: secretory cell def: "A cell that specializes in controlled release of one or more substances." [GOC:tfm, ISBN:0721662544] subset: cellxgene_subset xref: BTO:0003659 xref: FMA:86916 is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: capable_of GO:0032940 ! secretion by cell relationship: capable_of GO:0032940 ! secretion by cell [Term] id: CL:0000152 name: exocrine cell def: "A cell of an exocrine gland; i.e. a gland that discharges its secretion via a duct." [ISBN:0198547684] subset: general_cell_types_upper_slim xref: FMA:16014 is_a: CL:0000151 ! secretory cell is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000151 ! secretory cell intersection_of: part_of UBERON:0002365 ! exocrine gland relationship: part_of UBERON:0002365 ! exocrine gland [Term] id: CL:0000153 name: glycosaminoglycan secreting cell def: "A cell that secretes glycosaminoglycans." [GOC:tfm] synonym: "GAG secreting cell" EXACT [] synonym: "hyaluronic acid secreting cell" NARROW [] is_a: CL:0000327 ! extracellular matrix secreting cell is_a: CL:0000447 ! carbohydrate secreting cell [Term] id: CL:0000154 name: protein secreting cell is_a: CL:0000151 ! secretory cell intersection_of: CL:0000151 ! secretory cell intersection_of: capable_of GO:0009306 ! protein secretion relationship: capable_of GO:0009306 ! protein secretion [Term] id: CL:0000159 name: seromucus secreting cell is_a: CL:0000151 ! secretory cell [Term] id: CL:0000163 name: endocrine cell def: "A cell of an endocrine gland, ductless glands that secrete substances which are released directly into the circulation and which influence metabolism and other body functions." [MESH:D055098] subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "endocrinocyte" EXACT [] xref: FMA:83809 is_a: CL:0000151 ! secretory cell is_a: CL:0000164 {gci_relation="part_of", gci_filler="UBERON:0000945"} ! enteroendocrine cell is_a: CL:0000164 {gci_filler="UBERON:0000160", gci_relation="part_of"} ! enteroendocrine cell is_a: CL:0000164 {gci_filler="UBERON:0001264", gci_relation="part_of"} ! enteroendocrine cell is_a: CL:0000255 ! eukaryotic cell relationship: part_of UBERON:0000949 ! endocrine system property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000164 name: enteroendocrine cell def: "An endocrine cell that is located in the epithelium of the gastrointestinal tract or in the pancreas." [GOC:tfm, SANBI:mhl] subset: cellxgene_subset xref: BTO:0003865 xref: FMA:62930 xref: MESH:D019858 is_a: CL:0000150 ! glandular epithelial cell is_a: CL:0000163 ! endocrine cell [Term] id: CL:0000165 name: neuroendocrine cell def: "A neuron that is capable of some hormone secretion in response to neuronal signals." [MESH:D055099] comment: The neurosecretory cell is neither an ordinary neuron nor an endocrine cell, but a combination of both. Its neuronal features resemble those of ordinary neurons concerning both structure and function. The production of a visible secretory material marks the neurosecretory neuron as a gland cell, and the fact that extractable cellular products act in the manner of hormones places it in the realm of endocrine elements. \n\nThe modern definition of neurosecretion has evolved to include the release of any neuronal secretory product from a neuron. {xref="https://www.clinicalkey.com/#!/content/book/3-s2.0-B9780323555968000073", xref="PMID:5342440"} subset: cellxgene_subset subset: human_reference_atlas synonym: "neurosecretory cell" RELATED [] synonym: "neurosecretory neuron" RELATED [] xref: BTO:0002691 xref: FBbt:00005130 xref: FMA:83810 is_a: CL:0000163 ! endocrine cell is_a: CL:0000527 ! efferent neuron is_a: CL:0000710 ! neurecto-epithelial cell is_a: CL:1100001 ! secretory epithelial cell intersection_of: CL:0000540 ! neuron intersection_of: capable_of GO:0046879 ! hormone secretion property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000167 name: peptide hormone secreting cell is_a: CL:0000151 ! secretory cell intersection_of: CL:0000151 ! secretory cell intersection_of: capable_of GO:0030072 ! peptide hormone secretion relationship: capable_of GO:0030072 ! peptide hormone secretion [Term] id: CL:0000168 name: insulin secreting cell xref: BTO:0000783 is_a: CL:0000154 ! protein secreting cell is_a: CL:0000167 ! peptide hormone secreting cell is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000151 ! secretory cell intersection_of: capable_of GO:0030073 ! insulin secretion relationship: capable_of GO:0030073 ! insulin secretion [Term] id: CL:0000169 name: type B pancreatic cell def: "A cell that secretes insulin and is located towards the center of the islets of Langerhans." [GOC:tfm, http://en.wikipedia.org/wiki/Pancreatic_b_cell, ISBN:0517223651] comment: Pancreatic beta cells are also reportedly CD284-positive. Upon activation, they upregulate their CD14 expression. subset: cellxgene_subset subset: human_reference_atlas synonym: "B-cell of pancreatic islet" EXACT [FMA:70586] synonym: "beta cell" BROAD [ZFA:0009102] synonym: "beta cell islet" RELATED [MA:0002419] synonym: "beta cell of pancreatic islet" EXACT [FMA:70586] synonym: "insulin-secreting cell" EXACT [FMA:70586] synonym: "pancreatic B cell" EXACT [] synonym: "pancreatic B-cell" EXACT [FMA:70586] synonym: "pancreatic beta cell" EXACT [FMA:70586] synonym: "pancreatic islet core" EXACT [MA:0002419] synonym: "type B enteroendocrine cell" EXACT [FMA:70586] xref: BTO:0000783 xref: EV:0200009 xref: FMA:70586 xref: MA:0002419 xref: ncithesaurus:Beta_Cell is_a: CL:0000168 {is_inferred="true"} ! insulin secreting cell is_a: CL:0008024 ! pancreatic endocrine cell intersection_of: CL:0000164 ! enteroendocrine cell intersection_of: capable_of GO:0030073 ! insulin secretion intersection_of: part_of UBERON:0000006 ! islet of Langerhans relationship: develops_from CL:0002351 ! progenitor cell of endocrine pancreas relationship: part_of UBERON:0000006 ! islet of Langerhans property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000170 name: glucagon secreting cell def: "A cell that secretes glucagon." [GOC:tfm] synonym: "glucagon-secreting cell" EXACT [] xref: FMA:84045 is_a: CL:0000167 ! peptide hormone secreting cell intersection_of: CL:0000151 ! secretory cell intersection_of: capable_of GO:0070091 ! glucagon secretion relationship: capable_of GO:0070091 ! glucagon secretion [Term] id: CL:0000171 name: pancreatic A cell def: "A type of enteocrine cell found in the periphery of the islets of Langerhans that secretes glucagon." [GOC:tfm, ISBN:0721662544] subset: cellxgene_subset subset: human_reference_atlas synonym: "alpha cell of islet of Langerhans" EXACT [] synonym: "pancreatic alpha cell" EXACT [] xref: BTO:0000990 xref: FMA:70585 xref: MESH:D050416 is_a: CL:0002067 ! type A enteroendocrine cell is_a: CL:0008024 ! pancreatic endocrine cell intersection_of: CL:0002067 ! type A enteroendocrine cell intersection_of: part_of UBERON:0001264 ! pancreas relationship: develops_from CL:0002351 ! progenitor cell of endocrine pancreas relationship: part_of UBERON:0000006 ! islet of Langerhans property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000172 name: somatostatin secreting cell is_a: CL:0000167 ! peptide hormone secreting cell intersection_of: CL:0000151 ! secretory cell intersection_of: capable_of GO:0070253 ! somatostatin secretion relationship: capable_of GO:0070253 ! somatostatin secretion [Term] id: CL:0000173 name: pancreatic D cell def: "A D cell located in the pancreas. Peripherally placed within the islets like type A cells; contains somatostatin." [FMA:0517223651, GOC:tfm] subset: cellxgene_subset subset: human_reference_atlas synonym: "D-cell of pancreatic islet" EXACT [] synonym: "delta cell of islet" EXACT [] synonym: "delta cell of pancreatic islet" EXACT [] synonym: "pancreatic D-cell" EXACT [] synonym: "pancreatic delta cell" EXACT [] synonym: "somatostatin-secreting pancreatic cell" EXACT [] xref: BTO:0000803 xref: FMA:70587 is_a: CL:0000502 ! type D enteroendocrine cell is_a: CL:0008024 ! pancreatic endocrine cell intersection_of: CL:0000502 ! type D enteroendocrine cell intersection_of: part_of UBERON:0001264 ! pancreas relationship: develops_from CL:0002351 ! progenitor cell of endocrine pancreas relationship: part_of UBERON:0000006 ! islet of Langerhans property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000174 name: steroid hormone secreting cell is_a: CL:0000151 ! secretory cell intersection_of: CL:0000151 ! secretory cell intersection_of: capable_of GO:0035929 ! steroid hormone secretion relationship: capable_of GO:0035929 ! steroid hormone secretion [Term] id: CL:0000182 name: hepatocyte def: "The main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. Majority of cell population of liver, polygonal in shape, arranged in plates or trabeculae between sinusoids; may have single nucleus or binucleated." [GOC:tfm, http://en.wikipedia.org/wiki/Hepatocyte, ISBN:0412046911, MESH:D022781, PMID:19717280] comment: Hepatocytes are reportedly MHC Class I-positive and MHC Class II-positive. subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0000575 xref: CALOHA:TS-0454 xref: FMA:14515 is_a: CL:0000066 ! epithelial cell is_a: CL:0000417 ! endopolyploid cell is_a: UBERON:0004119 ! endoderm-derived structure relationship: capable_of GO:0006699 ! bile acid biosynthetic process relationship: capable_of GO:0098754 ! detoxification relationship: develops_from CL:0005026 ! hepatoblast relationship: part_of UBERON:0002107 ! liver property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000183 name: contractile cell def: "A cell whose primary function is to shorten." [FB:ma] subset: cellxgene_subset is_a: CL:0000000 ! cell [Term] id: CL:0000187 name: muscle cell def: "A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns." [MESH:D032342] subset: cellxgene_subset synonym: "muscle fiber" EXACT [] synonym: "myocyte" EXACT [] xref: BTO:0000888 xref: BTO:0000902 xref: CALOHA:TS-2032 xref: FBbt:00005074 xref: FMA:67328 xref: WBbt:0003675 is_a: CL:0000183 ! contractile cell is_a: CL:0000255 ! eukaryotic cell is_a: CL:0000393 ! electrically responsive cell is_a: UBERON:0004120 ! mesoderm-derived structure relationship: develops_from CL:0000056 ! myoblast property_value: depiction "https://www.swissbiopics.org/api/image/Muscle_cells.svg" xsd:anyURI [Term] id: CL:0000188 name: cell of skeletal muscle def: "A somatic cell located in skeletal muscle." [GOC:tfm] subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "skeletal muscle cell" EXACT [] xref: BTO:0004392 xref: CALOHA:TS-2158 xref: FMA:9727 xref: https://cellxgene.cziscience.com/cellguide/CL_0000188 xref: ZFA:0009115 {sssom:mapping_justification="vocab:UnspecifiedMatching"} is_a: CL:0000255 ! eukaryotic cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000000 ! cell intersection_of: part_of UBERON:0001134 ! skeletal muscle tissue relationship: part_of UBERON:0001134 ! skeletal muscle tissue property_value: RO:0002175 NCBITaxon:9606 property_value: term:description "Skeletal muscle cells, or myocytes, are essential for the musculoskeletal system, featuring a striated appearance from tightly packed sarcomeres. These elongated, multi-nucleated cells convert ATP into mechanical energ and are key for voluntary movement and posture. They also are responsible for maintaining body temperature, storing nutrients, and stabilizing joints.\nSkeletal muscle cells organize themselves tightly into bundles to form muscle fibers. Embedded within each of these cells are thousands of myofibrils, which are made up of the contractile proteins, actin (the thin filament), and myosin (the thick filament). Contraction of a skeletal muscle cell occurs when these myofibrils shorten, a process driven by the sliding of actin and myosin filaments over each other in a mechanism famously known as the sliding filament theory.\nAdditionally, skeletal muscle cells exhibit a high degree of plasticity, which allows for their adaptation in response to alterations in functional demands or damages. They have an innate regenerative capacity due to the presence of satellite cells—quiescent muscle stem cells that reside within the muscle fibers. Upon muscle injury, these satellite cells become activated, proliferate, and differentiate into new muscle cells, thereby contributing to the repair and growth of injured skeletal muscle. With this, skeletal muscle cells serve not only a pivotal biomechanical function but also possess a great capacity for self-healing and regeneration.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" xsd:string {xref="DOI:10.1002/cphy.c160033", xref="DOI:10.3390/biology10101056", xref="https://www.nature.com/scitable/topicpage/the-sliding-filament-theory-of-muscle-contraction-14567666/", xref="https://www.ncbi.nlm.nih.gov/books/NBK537139", xref="https://www.ncbi.nlm.nih.gov/books/NBK9961/"} [Term] id: CL:0000192 name: smooth muscle cell def: "A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast)." [http://en.wikipedia.org/wiki/Smooth_muscle_cell, MESH:D032389, PMID:9315361] subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "myocytes, smooth muscle" EXACT [MESH:D032389] synonym: "non-striated muscle cell" BROAD [] synonym: "SMCs" EXACT [PMID:9315361] synonym: "smooth muscle fiber" EXACT [] xref: BTO:0004576 xref: CALOHA:TS-2159 xref: FMA:14072 is_a: CL:0008000 ! non-striated muscle cell is_a: CL:0008007 ! visceral muscle cell relationship: develops_from CL:0000514 ! smooth muscle myoblast property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000197 name: sensory receptor cell def: "A cell that is capable of detection of a stimulus involved in sensory perception." [] synonym: "receptor cell" EXACT [] xref: MESH:D011984 is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: capable_of GO:0050906 ! detection of stimulus involved in sensory perception intersection_of: part_of UBERON:0001032 ! sensory system relationship: capable_of GO:0050906 ! detection of stimulus involved in sensory perception relationship: part_of UBERON:0001032 ! sensory system [Term] id: CL:0000206 name: chemoreceptor cell def: "A cell specialized to detect chemical substances and relay that information centrally in the nervous system. Chemoreceptors may monitor external stimuli, as in taste and olfaction, or internal stimuli, such as the concentrations of oxygen and carbon dioxide in the blood." [MESH:D002628] is_a: CL:0000197 ! sensory receptor cell intersection_of: CL:0000197 ! sensory receptor cell intersection_of: capable_of GO:0050907 ! detection of chemical stimulus involved in sensory perception relationship: capable_of GO:0050907 ! detection of chemical stimulus involved in sensory perception [Term] id: CL:0000210 name: photoreceptor cell def: "A cell specialized to detect and transduce light." [MESH:D010786] subset: cellxgene_subset xref: BTO:0001060 xref: CALOHA:TS-0868 xref: FMA:86740 is_a: CL:0000006 {is_inferred="true"} ! neuronal receptor cell intersection_of: CL:0000540 ! neuron intersection_of: capable_of GO:0050962 ! detection of light stimulus involved in sensory perception relationship: capable_of GO:0050962 ! detection of light stimulus involved in sensory perception property_value: depiction "https://www.swissbiopics.org/api/image/Photoreceptor_cell.svg" xsd:anyURI [Term] id: CL:0000211 name: electrically active cell def: "A cell whose function is determined by the generation or the reception of an electric signal." [FB:ma] is_a: CL:0000000 ! cell [Term] id: CL:0000213 name: lining cell def: "A cell within an epithelial cell sheet whose main function is to act as an internal or external covering for a tissue or an organism." [JB:jb] synonym: "boundary cell" EXACT [] is_a: CL:0000215 ! barrier cell [Term] id: CL:0000214 name: synovial cell def: "A cell located in the synovial joint." [] synonym: "synoviocyte" EXACT [] xref: CALOHA:TS-0995 is_a: CL:0000213 ! lining cell is_a: CL:0002078 {is_inferred="true"} ! meso-epithelial cell relationship: part_of UBERON:0002217 ! synovial joint [Term] id: CL:0000215 name: barrier cell def: "A cell whose primary function is to prevent the transport of stuff across compartments." [JB:jb] is_a: CL:0000000 ! cell [Term] id: CL:0000216 name: Sertoli cell def: "A supporting cell projecting inward from the basement membrane of seminiferous tubules. They surround and nourish the developing male germ cells and secrete androgen binding protein. Their tight junctions with the spermatogonia and spermatocytes provide a blood-testis barrier." [MESH:D012708] subset: cellxgene_subset xref: BTO:0001238 xref: CALOHA:TS-0922 xref: FMA:72298 xref: VHOG:0001348 is_a: CL:0000511 ! androgen binding protein secreting cell is_a: CL:0000630 {is_inferred="true"} ! supporting cell is_a: CL:0002625 ! seminiferous tubule epithelial cell is_a: CL:1100001 ! secretory epithelial cell intersection_of: CL:0000630 ! supporting cell intersection_of: part_of UBERON:0001343 ! seminiferous tubule of testis [Term] id: CL:0000219 name: motile cell def: "A cell that moves by its own activities." [FB:ma] is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: capable_of GO:0048870 ! cell motility relationship: capable_of GO:0048870 ! cell motility [Term] id: CL:0000221 name: ectodermal cell def: "A cell of the outer of the three germ layers of the embryo." [MESH:D004475] subset: cellxgene_subset synonym: "ectoderm cell" EXACT [] xref: FMA:72549 xref: ZFA:0009137 {sssom:mapping_justification="vocab:UnspecifiedMatching"} is_a: CL:0000255 ! eukaryotic cell is_a: CL:0002321 ! embryonic cell (metazoa) relationship: part_of UBERON:0000924 ! ectoderm [Term] id: CL:0000222 name: mesodermal cell def: "A cell of the middle germ layer of the embryo." [MESH:D008648] subset: cellxgene_subset synonym: "mesoblast" EXACT [] synonym: "mesoderm cell" EXACT [] xref: FMA:72554 is_a: CL:0000255 ! eukaryotic cell is_a: CL:0002321 ! embryonic cell (metazoa) relationship: part_of UBERON:0000926 ! mesoderm [Term] id: CL:0000223 name: endodermal cell def: "A cell of the inner of the three germ layers of the embryo." [MESH:D004707] synonym: "endoderm cell" EXACT [] xref: FMA:72555 is_a: CL:0000255 ! eukaryotic cell is_a: CL:0002321 ! embryonic cell (metazoa) relationship: part_of UBERON:0000925 ! endoderm [Term] id: CL:0000225 name: anucleate cell def: "A cell that lacks a nucleus." [FB:ma] synonym: "non-nucleated cell" EXACT [] xref: FMA:68647 is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: has_characteristic PATO:0001405 ! anucleate disjoint_from: CL:0002242 ! nucleate cell relationship: has_characteristic PATO:0001405 ! anucleate [Term] id: CL:0000226 name: single nucleate cell def: "A cell with a single nucleus." [FB:ma, GOC:tfm] is_a: CL:0000255 ! eukaryotic cell is_a: CL:0002242 ! nucleate cell intersection_of: CL:0000000 ! cell intersection_of: has_characteristic PATO:0001407 ! mononucleate relationship: has_characteristic PATO:0001407 ! mononucleate [Term] id: CL:0000227 name: binucleate cell is_a: CL:0000228 ! multinucleate cell intersection_of: CL:0000000 ! cell intersection_of: has_characteristic PATO:0001406 ! binucleate relationship: has_characteristic PATO:0001406 ! binucleate [Term] id: CL:0000228 name: multinucleate cell def: "A cell with more than one nucleus." [FB:ma] synonym: "syncitium" EXACT [] synonym: "syncytial cell" EXACT [] synonym: "syncytium" EXACT [] xref: AEO:0000203 xref: WBbt:0008074 is_a: CL:0000255 ! eukaryotic cell is_a: CL:0002242 ! nucleate cell intersection_of: CL:0000000 ! cell intersection_of: has_characteristic PATO:0001908 ! multinucleate relationship: has_characteristic PATO:0001908 ! multinucleate [Term] id: CL:0000232 name: erythrocyte def: "A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen." [GOC:tfm, MESH:D004912] subset: blood_and_immune_upper_slim subset: cellxgene_subset subset: human_reference_atlas synonym: "RBC" EXACT [] synonym: "red blood cell" EXACT [] xref: BTO:0000424 xref: CALOHA:TS-0290 xref: FMA:81100 is_a: CL:0000081 ! blood cell is_a: CL:0000329 ! oxygen accumulating cell is_a: CL:0000764 {is_inferred="true"} ! erythroid lineage cell intersection_of: CL:0000764 ! erythroid lineage cell intersection_of: capable_of GO:0008015 ! blood circulation intersection_of: capable_of GO:0015671 ! oxygen transport intersection_of: CL:4030045 GO:0005840 ! lacks_part ribosome intersection_of: CL:4030046 PR:000001945 ! lacks_plasma_membrane_part transferrin receptor protein 1 intersection_of: has_characteristic PATO:0002039 ! biconcave relationship: CL:4030045 GO:0005840 ! lacks_part ribosome relationship: CL:4030046 PR:000001945 ! lacks_plasma_membrane_part transferrin receptor protein 1 relationship: develops_from CL:0000558 ! reticulocyte relationship: has_characteristic PATO:0002039 ! biconcave property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000234 name: phagocyte def: "Any cell capable of ingesting particulate matter via phagocytosis." [GOC:add, ISBN:0721601464] subset: cellxgene_subset xref: BTO:0001044 xref: FMA:83806 xref: MESH:D010586 is_a: CL:0000219 ! motile cell is_a: CL:0000325 ! stuff accumulating cell is_a: CL:0000473 ! defensive cell intersection_of: CL:0000000 ! cell intersection_of: capable_of GO:0006909 ! phagocytosis relationship: capable_of GO:0006909 ! phagocytosis [Term] id: CL:0000255 name: eukaryotic cell def: "Any cell that in taxon some Eukaryota." [FBC:Autogenerated] subset: cellxgene_subset xref: MESH:D005057 is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: in_taxon NCBITaxon:2759 ! Eukaryota intersection_of: only_in_taxon NCBITaxon:2759 ! Eukaryota relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota [Term] id: CL:0000257 name: Eumycetozoan cell is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: only_in_taxon NCBITaxon:142796 ! Eumycetozoa relationship: only_in_taxon NCBITaxon:142796 ! Eumycetozoa [Term] id: CL:0000287 name: eye photoreceptor cell subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas is_a: CL:0000210 ! photoreceptor cell intersection_of: CL:0000210 ! photoreceptor cell intersection_of: part_of UBERON:0000970 ! eye relationship: part_of UBERON:0000970 ! eye property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000293 name: structural cell def: "A cell whose primary function is to provide structural support, to provide strength and physical integrity to the organism." [TAIR:sr] is_a: CL:0000000 ! cell [Term] id: CL:0000300 name: gamete def: "A mature sexual reproductive cell having a single set of unpaired chromosomes." [GOC:tfm, ISBN:0721662544] synonym: "haploid germ cell" RELATED [] synonym: "haploid nucleated cell" EXACT [] xref: CALOHA:TS-0395 xref: FBbt:00005412 xref: FMA:18649 is_a: CL:0000413 ! haploid cell is_a: CL:0000586 {is_inferred="true"} ! germ cell intersection_of: CL:0000586 ! germ cell intersection_of: capable_of GO:0009566 ! fertilization intersection_of: has_characteristic PATO:0001375 ! haploid relationship: capable_of GO:0009566 ! fertilization [Term] id: CL:0000306 name: crystallin accumulating cell subset: eye_upper_slim synonym: "lens cell" EXACT [] is_a: CL:0000325 ! stuff accumulating cell [Term] id: CL:0000313 name: serous secreting cell def: "Columnar glandular cell with irregular nucleus, copious granular endoplasmic reticulum and supranuclear granules. Secretes a watery fluid containing proteins known as serous fluid." [GOC:tfm, ISBN:0517223651, ISBN:0721662544] subset: cellxgene_subset synonym: "serous cell" EXACT [] xref: BTO:0003687 xref: FMA:62511 is_a: CL:0000159 ! seromucus secreting cell [Term] id: CL:0000319 name: mucus secreting cell subset: cellxgene_subset synonym: "mucous cell" EXACT [] xref: BTO:0003689 is_a: CL:0000159 ! seromucus secreting cell intersection_of: CL:0000151 ! secretory cell intersection_of: capable_of GO:0070254 ! mucus secretion relationship: capable_of GO:0070254 ! mucus secretion [Term] id: CL:0000325 name: stuff accumulating cell def: "A cell that is specialised to accumulate a particular substance(s)." [FB:ma] subset: ubprop:upper_level is_a: CL:0000000 ! cell [Term] id: CL:0000327 name: extracellular matrix secreting cell is_a: CL:0000499 ! stromal cell [Term] id: CL:0000329 name: oxygen accumulating cell is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: capable_of GO:0015671 ! oxygen transport relationship: capable_of GO:0015671 ! oxygen transport [Term] id: CL:0000333 name: migratory neural crest cell def: "A cell derived from the specialized ectoderm flanking each side of the embryonic neural plate, which after the closure of the neural tube, forms masses of cells that migrate out from the dorsal aspect of the neural tube to spread throughout the body." [doi:10.1016/j.stem.2015.02.017] xref: FMA:86667 is_a: CL:0000219 ! motile cell is_a: CL:0011012 ! neural crest cell is_a: CL:0011026 ! progenitor cell is_a: UBERON:0010313 ! neural crest-derived structure relationship: develops_from CL:0007004 ! premigratory neural crest cell [Term] id: CL:0000335 name: mesenchyme condensation cell def: "A mesenchymal cell in embryonic development found in a contracting mass and that gives rise to osteoprogenitors." [GOC:tfm, PMID:5025404] is_a: CL:0008019 ! mesenchymal cell [Term] id: CL:0000347 name: scleral cell def: "A cell of the sclera of the eye." [GOC:add] subset: eye_upper_slim is_a: CL:0000255 ! eukaryotic cell is_a: CL:0000293 ! structural cell is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: CL:0000293 ! structural cell intersection_of: part_of UBERON:0001773 ! sclera relationship: develops_from CL:0000008 ! migratory cranial neural crest cell relationship: part_of UBERON:0001773 ! sclera [Term] id: CL:0000348 name: choroidal cell of the eye def: "A structural cell that is part of optic choroid." [GOC:add] subset: eye_upper_slim is_a: CL:0000255 ! eukaryotic cell is_a: CL:0000293 ! structural cell is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: CL:0000293 ! structural cell intersection_of: part_of UBERON:0001776 ! optic choroid relationship: develops_from CL:0000008 ! migratory cranial neural crest cell relationship: part_of UBERON:0001776 ! optic choroid [Term] id: CL:0000349 name: extraembryonic cell subset: general_cell_types_upper_slim is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: part_of UBERON:0000478 ! extraembryonic structure relationship: part_of UBERON:0000478 ! extraembryonic structure [Term] id: CL:0000351 name: trophoblast cell def: "A cell lining the outside of the blastocyst. After binding to the endometrium, trophoblast cells develop into two distinct layers, an inner layer of mononuclear cytotrophoblast cells and an outer layer of continuous multinuclear cytoplasm, the syncytiotrophoblast cells, which form the early fetal-maternal interface." [GOC:tfm, MESH:D014327] synonym: "trophoblastic cell" EXACT [] xref: FMA:83028 is_a: CL:0000349 {is_inferred="true"} ! extraembryonic cell relationship: part_of UBERON:0000358 ! blastocyst [Term] id: CL:0000352 name: epiblast cell def: "A cell of the outer layer of a blastula that gives rise to the ectoderm after gastrulation." [GOC:tfm, ISBN:0618947256] is_a: CL:0000052 ! totipotent stem cell [Term] id: CL:0000353 name: blastoderm cell def: "An undifferentiated cell produced by early cleavages of the fertilized egg (zygote)." [MESH:D001756] synonym: "blastomere" EXACT [] xref: BTO:0001473 xref: FMA:72551 is_a: CL:0000007 ! early embryonic cell (metazoa) [Term] id: CL:0000354 name: blastemal cell synonym: "blastema cell" EXACT [] xref: ncithesaurus:Blastemal_Cell is_a: CL:0000048 ! multi fate stem cell [Term] id: CL:0000355 name: multi-potent skeletal muscle stem cell def: "A multifate stem cell found in skeletal muscle than can differentiate into many different cell types, including muscle. Distinct cell type from satellite cell." [PMID:18282570] comment: Multi-potency demonstrated ex vivo. At the time of writing, it is unclear whether the endogenous population differentiates into multiple cell types in vivo. xref: FMA:86767 is_a: CL:0000048 {is_inferred="true"} ! multi fate stem cell is_a: CL:0000188 ! cell of skeletal muscle intersection_of: CL:0000048 ! multi fate stem cell intersection_of: part_of UBERON:0001134 ! skeletal muscle tissue [Term] id: CL:0000358 name: sphincter associated smooth muscle cell def: "A smooth muscle cell that is part of a sphincter. A sphincter is a typically circular muscle that normally maintains constriction of a natural body passage or orifice and which relaxes as required by normal physiological functioning." [GOC:cjm] is_a: CL:0000192 {is_inferred="true"} ! smooth muscle cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0004590 ! sphincter muscle relationship: part_of UBERON:0004590 ! sphincter muscle [Term] id: CL:0000359 name: vascular associated smooth muscle cell def: "A smooth muscle cell associated with the vasculature." [GOC:dsd, GOC:tfm] subset: cellxgene_subset subset: human_reference_atlas synonym: "vascular smooth muscle cell" EXACT [] synonym: "VSMC" EXACT [] is_a: CL:0000192 {is_inferred="true"} ! smooth muscle cell is_a: CL:4033054 ! perivascular cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0002049 ! vasculature relationship: part_of UBERON:0002049 ! vasculature property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000362 name: epidermal cell def: "An epithelial cell of the integument (the outer layer of an organism)." [Flybase:dsj, MA:ma] subset: cellxgene_subset synonym: "cell of epidermis" EXACT [FMA:62411] synonym: "epithelial cell of skin" NARROW [FMA:62411] xref: BTO:0001470 xref: CALOHA:TS-0283 xref: FMA:62411 xref: MESH:D000078404 xref: ZFA:0009183 {sssom:mapping_justification="vocab:UnspecifiedMatching"} is_a: CL:0002159 ! general ecto-epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0007376 ! outer epithelium relationship: part_of UBERON:0007376 ! outer epithelium [Term] id: CL:0000365 name: animal zygote def: "Diploid cell produced by the fusion of sperm cell nucleus and egg cell." [ISBN:0471245208] synonym: "zygote" BROAD [] xref: BTO:0000854 xref: EHDAA2:0004546 xref: FMA:72395 is_a: CL:0000007 ! early embryonic cell (metazoa) is_a: CL:0000255 ! eukaryotic cell is_a: CL:0010017 ! zygote intersection_of: CL:0010017 ! zygote intersection_of: only_in_taxon NCBITaxon:33208 ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa [Term] id: CL:0000393 name: electrically responsive cell def: "A cell whose function is determined by its response to an electric signal." [FB:ma] is_a: CL:0000211 ! electrically active cell [Term] id: CL:0000397 name: ganglion interneuron subset: cellxgene_subset is_a: CL:0000099 {is_inferred="true"} ! interneuron intersection_of: CL:0000099 ! interneuron intersection_of: has_soma_location UBERON:0000045 ! ganglion relationship: has_soma_location UBERON:0000045 ! ganglion [Term] id: CL:0000402 name: CNS interneuron def: "An interneuron that has its cell body in a central nervous system." [doi:10.1016/B978-0-12-817424-1.00001-X] comment: Interneurons are commonly described as being only found in the central nervous system. However, in CL we define 'interneuron' more broadly as any neuron that is neither a motor neuron nor a sensory neuron, regardless of its location, so we need this term to refer strictly to interneurons of the central nervous system. subset: human_reference_atlas is_a: CL:0000099 ! interneuron is_a: CL:2000029 ! central nervous system neuron intersection_of: CL:0000099 ! interneuron intersection_of: has_soma_location UBERON:0001017 ! central nervous system property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000404 name: electrically signaling cell def: "A cell that initiates an electrical signal and passes that signal to another cell." [FB:ma] is_a: CL:0000211 ! electrically active cell [Term] id: CL:0000408 name: male gamete xref: BTO:0001277 xref: CALOHA:TS-0949 is_a: CL:0000015 {is_inferred="true"} ! male germ cell is_a: CL:0000300 {is_inferred="true"} ! gamete intersection_of: CL:0000015 ! male germ cell intersection_of: capable_of GO:0009566 ! fertilization intersection_of: has_characteristic PATO:0001375 ! haploid [Term] id: CL:0000412 name: polyploid cell def: "A cell that contains more than two haploid sets of chromosomes." [FB:ma, https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Biology_(Kimball)/07%3A_Cell_Division/7.04%3A_Polyploidy, PMID:32646579] is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: has_characteristic PATO:0001377 ! polyploid relationship: has_characteristic PATO:0001377 ! polyploid [Term] id: CL:0000413 name: haploid cell def: "A cell whose nucleus contains a single haploid genome." [FB:ma, GOC:tfm] is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: has_characteristic PATO:0001375 ! haploid relationship: has_characteristic PATO:0001375 ! haploid [Term] id: CL:0000417 name: endopolyploid cell is_a: CL:0000412 ! polyploid cell [Term] id: CL:0000447 name: carbohydrate secreting cell is_a: CL:0000151 ! secretory cell [Term] id: CL:0000451 name: dendritic cell def: "A cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. These cells are lineage negative (CD3-negative, CD19-negative, CD34-negative, and CD56-negative)." [GOC:add, ISBN:0781735149] subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "interdigitating cell" RELATED [] synonym: "veiled cell" RELATED [] xref: BTO:0002042 xref: CALOHA:TS-0194 xref: FMA:83036 xref: MESH:D003713 is_a: CL:0000113 ! mononuclear phagocyte is_a: CL:0000145 ! professional antigen presenting cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000738 ! leukocyte intersection_of: capable_of GO:0001816 ! cytokine production intersection_of: capable_of GO:0002504 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II intersection_of: capable_of GO:0019882 ! antigen processing and presentation intersection_of: capable_of GO:0045580 ! regulation of T cell differentiation intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule intersection_of: CL:4030046 PR:000001003 ! lacks_plasma_membrane_part CD34 molecule intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 intersection_of: has_characteristic PATO:0001407 ! mononucleate intersection_of: has_part GO:0042613 ! MHC class II protein complex disjoint_from: CL:0000542 ! lymphocyte relationship: capable_of GO:0001816 ! cytokine production relationship: capable_of GO:0045580 ! regulation of T cell differentiation relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule relationship: CL:4030046 PR:000001003 ! lacks_plasma_membrane_part CD34 molecule relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 relationship: has_part GO:0042613 ! MHC class II protein complex property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000457 name: biogenic amine secreting cell is_a: CL:0000151 ! secretory cell [Term] id: CL:0000458 name: serotonin secreting cell def: "A cell type that secretes 5-Hydroxytryptamine (serotonin)." [GOC:tfm, PMID:19630576] synonym: "5-HT secreting cell" EXACT [] synonym: "5-Hydroxytryptamine secreting cell" EXACT [] is_a: CL:0000457 ! biogenic amine secreting cell intersection_of: CL:0000151 ! secretory cell intersection_of: capable_of GO:0001820 ! serotonin secretion relationship: capable_of GO:0001820 ! serotonin secretion [Term] id: CL:0000459 name: noradrenergic cell def: "A cell capable of producting norepiniphrine. Norepiniphrine is a catecholamine with multiple roles including as a hormone and a neurotransmitter. In addition, epiniphrine is synthesized from norepiniphrine by the actions of the phenylethanolamine N-methyltransferase enzyme." [GOC:tfm, ISBN:068340007X] synonym: "noradrenaline secreting cell" EXACT [] synonym: "norepinephrin secreting cell" EXACT [] synonym: "norepinephrine secreting cell" EXACT [] is_a: CL:0000457 ! biogenic amine secreting cell intersection_of: CL:0000151 ! secretory cell intersection_of: capable_of GO:0048243 ! norepinephrine secretion relationship: capable_of GO:0048243 ! norepinephrine secretion [Term] id: CL:0000473 name: defensive cell def: "A cell whose primary function is to protect the organism." [JB:jb] is_a: CL:0000000 ! cell [Term] id: CL:0000488 name: visible light photoreceptor cell def: "A photoreceptor cell that detects visible light." [GOC:tfm] is_a: CL:0000210 ! photoreceptor cell intersection_of: CL:0000210 ! photoreceptor cell intersection_of: capable_of GO:0009584 ! detection of visible light relationship: capable_of GO:0009584 ! detection of visible light [Term] id: CL:0000499 name: stromal cell def: "A connective tissue cell of an organ found in the loose connective tissue. These are most often associated with the uterine mucosa and the ovary as well as the hematopoietic system and elsewhere." [GOC:tfm, MESH:D017154] subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas xref: BTO:0002064 xref: FMA:83624 is_a: CL:0002320 ! connective tissue cell relationship: develops_from CL:0000134 ! mesenchymal stem cell property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000502 name: type D enteroendocrine cell def: "A cell found throughout the gastrointestinal tract and in the pancreas. They secrete somatostatin in both an endocrine and paracrine manner. Somatostatin inhibits gastrin, cholecystokinin, insulin, glucagon, pancreatic enzymes, and gastric hydrochloric acid. A variety of substances which inhibit gastric acid secretion (vasoactive intestinal peptide, calcitonin gene-related peptide, cholecystokinin, beta-adrenergic agonists, and gastric inhibitory peptide) are thought to act by releasing somatostatin." [MESH:D019864] subset: cellxgene_subset synonym: "D cell" EXACT [] xref: FMA:62935 is_a: CL:0000164 ! enteroendocrine cell is_a: CL:0000172 ! somatostatin secreting cell [Term] id: CL:0000506 name: enkephalin secreting cell def: "An endorphine cell that secretes enkephalin." [GO:tfm] is_a: CL:0000507 ! endorphin secreting cell [Term] id: CL:0000507 name: endorphin secreting cell def: "A peptide hormone secreting cell that secretes endorphin." [GO:tfm] is_a: CL:0000167 ! peptide hormone secreting cell [Term] id: CL:0000508 name: type G enteroendocrine cell def: "An endocrine cell found in the pyloric gland mucosa (antral mucosa) of the stomach of mammals and responsible for the secretion of gastrin and enkephalin. Most abundant in pyloric antrum, pyramidal in form with a narrow apex bearing long microvilli." [GOC:tfm, ISBN:0517223651, MESH:D019863] subset: cellxgene_subset synonym: "G cell" EXACT [] xref: BTO:0004108 xref: FMA:67609 is_a: CL:0000164 ! enteroendocrine cell is_a: CL:0000506 ! enkephalin secreting cell is_a: CL:0000509 ! gastrin secreting cell is_a: CL:0002180 ! mucous cell of stomach relationship: part_of UBERON:0004997 ! mucosa of pyloric antrum [Term] id: CL:0000509 name: gastrin secreting cell def: "A peptide hormone secreting cell that secretes gastrin." [GO:tfm] subset: human_reference_atlas is_a: CL:0000167 ! peptide hormone secreting cell property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000511 name: androgen binding protein secreting cell def: "A peptide hormone secreting cell that secretes androgen binding protein." [GO:tfm] is_a: CL:0000154 ! protein secreting cell [Term] id: CL:0000513 name: cardiac muscle myoblast def: "A precursor cell destined to differentiate into cardiac muscle cell." [GOC:tfm, MESH:D032386] subset: cellxgene_subset synonym: "cardiac muscle progenitor cell" EXACT [] synonym: "cardiomyocyte progenitor cell" EXACT [] xref: FMA:84797 is_a: CL:0002494 ! cardiocyte is_a: CL:0010021 ! cardiac myoblast intersection_of: CL:0000056 ! myoblast intersection_of: develops_into CL:0000746 ! cardiac muscle cell intersection_of: part_of UBERON:0001133 ! cardiac muscle tissue relationship: part_of UBERON:0001133 ! cardiac muscle tissue [Term] id: CL:0000514 name: smooth muscle myoblast def: "A precursor cell destined to differentiate into smooth muscle myocytes." [GOC:tfm, MESH:D032390] subset: cellxgene_subset synonym: "myoblast, smooth muscle" EXACT [MESH:D032390] synonym: "satellite cell" RELATED [] xref: FMA:84798 is_a: CL:0000056 ! myoblast intersection_of: CL:0000056 ! myoblast intersection_of: develops_into CL:0000192 ! smooth muscle cell relationship: develops_into CL:0000192 ! smooth muscle cell [Term] id: CL:0000515 name: skeletal muscle myoblast def: "A myoblast that differentiates into skeletal muscle fibers." [SANBI:mhl] synonym: "skeletal myoblast" EXACT [] xref: FMA:84799 is_a: CL:0000056 ! myoblast is_a: CL:0011026 ! progenitor cell intersection_of: CL:0000056 ! myoblast intersection_of: develops_into CL:0008002 ! skeletal muscle fiber relationship: develops_from CL:0000355 ! multi-potent skeletal muscle stem cell relationship: develops_into CL:0008002 ! skeletal muscle fiber [Term] id: CL:0000518 name: phagocyte (sensu Vertebrata) def: "A phagocyte in vertebrates that is able to phagocytosis." [GOC:tfm] is_a: CL:0000234 ! phagocyte is_a: CL:0000255 ! eukaryotic cell relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata [Term] id: CL:0000521 name: fungal cell is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: only_in_taxon NCBITaxon:4751 ! Fungi relationship: only_in_taxon NCBITaxon:4751 ! Fungi [Term] id: CL:0000525 name: syncytiotrophoblast cell def: "A cell from the outer syncytial layer of the trophoblast of an early mammalian embryo, directly associated with the maternal blood supply. It secretes hCG in order to maintain progesterone secretion and sustain a pregnancy." [GOC:tfm, ISBN:0323052908] subset: cellxgene_subset subset: human_reference_atlas synonym: "plasmidotrophoblast cell" RELATED [] synonym: "syncytial trophoblast cell" EXACT [PMID:11787150] synonym: "syncytiotrophoblastic cell" EXACT [PMID:21733368] synonym: "syntrophoblast cell" RELATED [] xref: FMA:83043 is_a: CL:0000228 ! multinucleate cell is_a: CL:0000351 ! trophoblast cell intersection_of: CL:0000351 ! trophoblast cell intersection_of: has_characteristic PATO:0001908 ! multinucleate relationship: part_of UBERON:0000371 ! syncytiotrophoblast property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://github.com/obophenotype/cell-ontology/issues/2100" xsd:string [Term] id: CL:0000526 name: afferent neuron def: "A neuron which conveys sensory information centrally from the periphery." [GOC:tfm, MESH:D009475] subset: human_reference_atlas synonym: "input neuron" EXACT [] xref: FMA:87653 is_a: CL:0000540 ! neuron property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000527 name: efferent neuron def: "A neuron which sends impulses peripherally to activate muscles or secretory cells." [MESH:D009476] synonym: "output neuron" EXACT [] is_a: CL:0000540 ! neuron [Term] id: CL:0000540 name: neuron def: "The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system." [http://en.wikipedia.org/wiki/Neuron, MESH:D009474] comment: These cells are also reportedly CD4-negative and CD200-positive. They are also capable of producing CD40L and IFN-gamma. subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "nerve cell" EXACT [] xref: BTO:0000938 xref: CALOHA:TS-0683 xref: FBbt:00005106 xref: FMA:54527 xref: VHOG:0001483 xref: WBbt:0003679 is_a: CL:0000393 ! electrically responsive cell is_a: CL:0000404 ! electrically signaling cell is_a: CL:0002319 ! neural cell relationship: capable_of GO:0019226 ! transmission of nerve impulse relationship: develops_from CL:0000031 {gci_relation="in_taxon", gci_filler="NCBITaxon:7742", xref="https://github.com/obophenotype/cell-ontology/issues/757"} ! neuroblast (sensu Vertebrata) property_value: depiction "https://www.swissbiopics.org/api/image/Neuron_cells.svg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000542 name: lymphocyte def: "A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin." [GOC:add, ISBN:0683073696, ISBN:0781735149] comment: Editors note: consider adding taxon constraint to vertebrata (PMID:18025161) subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0000775 xref: CALOHA:TS-0583 xref: FMA:62863 xref: MESH:D008214 xref: VHOG:0001535 is_a: CL:0000842 ! mononuclear cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000738 ! leukocyte intersection_of: has_characteristic PATO:0001407 ! mononucleate intersection_of: has_characteristic PATO:0040072 ! high nuclear/cytoplasmic ratio intersection_of: has_part CL:0017500 ! neutrophillic cytoplasm intersection_of: has_part GO:0000792 ! heterochromatin disjoint_from: CL:0000766 ! myeloid leukocyte relationship: develops_from CL:0000051 ! common lymphoid progenitor relationship: has_characteristic PATO:0040072 ! high nuclear/cytoplasmic ratio relationship: has_part CL:0017500 ! neutrophillic cytoplasm relationship: has_part GO:0000792 ! heterochromatin property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000547 name: proerythroblast def: "An immature, nucleated erythrocyte occupying the stage of erythropoeisis that follows formation of erythroid progenitor cells. This cell is CD71-positive, has both a nucleus and a nucleolus, and lacks hematopoeitic lineage markers." [ISBN:0721601464, PMID:1638021] subset: blood_and_immune_upper_slim subset: cellxgene_subset synonym: "pronormoblast" RELATED [] synonym: "rubriblast" EXACT [ISBN:0721601464] xref: FMA:83518 is_a: CL:0000764 {is_inferred="true"} ! erythroid lineage cell is_a: CL:0002242 ! nucleate cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000764 ! erythroid lineage cell intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G intersection_of: has_characteristic PATO:0002505 ! nucleated intersection_of: has_characteristic PATO:0040072 ! high nuclear/cytoplasmic ratio intersection_of: has_part CL:0017503 ! basophilic cytoplasm intersection_of: has_part GO:0005730 ! nucleolus intersection_of: has_plasma_membrane_part PR:000001945 ! transferrin receptor protein 1 relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G relationship: develops_from CL:0000038 ! erythroid progenitor cell relationship: has_characteristic PATO:0040072 ! high nuclear/cytoplasmic ratio relationship: has_part CL:0017503 ! basophilic cytoplasm relationship: has_part GO:0005730 ! nucleolus relationship: has_plasma_membrane_part PR:000001945 ! transferrin receptor protein 1 [Term] id: CL:0000549 name: basophilic erythroblast def: "A nucleated immature erythrocyte, having cytoplasm generally similar to that of the earlier proerythroblast but sometimes even more basophilic, and usually regular in outline. The nucleus is still relatively large, but the chromatin strands are thicker and more deeply staining, giving a coarser appearance; the nucleoli have disappeared. This cell is CD71-positive and lacks hematopoeitic lineage markers." [GOC:tfm, ISBN:0721601464] synonym: "basophilic normoblast" EXACT [ISBN:0721601464] synonym: "early erythroblast" EXACT [ISBN:0721601464] synonym: "early normoblast" EXACT [ISBN:0721601464] synonym: "prorubricyte" EXACT [ISBN:0721601464] xref: FMA:83505 is_a: CL:0000765 {is_inferred="true"} ! erythroblast is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000765 ! erythroblast intersection_of: has_part CL:0017503 ! basophilic cytoplasm intersection_of: has_part GO:0000792 ! heterochromatin intersection_of: has_plasma_membrane_part PR:000001945 ! transferrin receptor protein 1 relationship: has_part CL:0017503 ! basophilic cytoplasm relationship: has_part GO:0000792 ! heterochromatin relationship: has_plasma_membrane_part PR:000001945 ! transferrin receptor protein 1 [Term] id: CL:0000550 name: polychromatophilic erythroblast def: "A nucleated, immature erythrocyte in which the nucleus occupies a relatively smaller part of the cell than in its precursor, the basophilic erythroblast. The cytoplasm is beginning to acquire hemoglobin and thus is no longer a purely basophilic, but takes on acidophilic aspects, which becomes progressively more marked as the cell matures. The chromatin of the nucleus is arranged in coarse, deeply staining clumps. This cell is CD71-positive and lacks hematopoeitic lineage markers." [ISBN:0721601464] synonym: "intermediate erythroblast" EXACT [ISBN:0721601464] synonym: "intermediate normoblast" EXACT [ISBN:0721601464] synonym: "polychromatic erythroblast" EXACT [ISBN:0721601464] synonym: "polychromatic normoblast" EXACT [ISBN:0721601464] synonym: "polychromatophilic normoblast" EXACT [ISBN:0721601464] synonym: "rubricyte" EXACT [ISBN:0721601464] xref: FMA:83506 is_a: CL:0000765 {is_inferred="true"} ! erythroblast is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000765 ! erythroblast intersection_of: has_part CL:0017504 ! polychromatophilic cytoplasm intersection_of: has_part GO:0000792 ! heterochromatin intersection_of: has_plasma_membrane_part PR:000001945 ! transferrin receptor protein 1 relationship: develops_from CL:0000549 ! basophilic erythroblast relationship: has_part CL:0017504 ! polychromatophilic cytoplasm relationship: has_part GO:0000792 ! heterochromatin relationship: has_plasma_membrane_part PR:000001945 ! transferrin receptor protein 1 [Term] id: CL:0000552 name: orthochromatic erythroblast def: "The final stage of the nucleated, immature erythrocyte, before nuclear loss. Typically the cytoplasm is described as acidophilic, but it still shows a faint polychromatic tint. The nucleus is small and initially may still have coarse, clumped chromatin, as in its precursor, the polychromatophilic erythroblast, but ultimately it becomes pyknotic, and appears as a deeply staining, blue-black, homogeneous structureless mass. The nucleus is often eccentric and sometimes lobulated." [ISBN:0721601464] synonym: "acidophilic erythroblast" EXACT [ISBN:0721601464] synonym: "eosinophilic erythroblast" EXACT [ISBN:0721601464] synonym: "late erythoblast" EXACT [] synonym: "orthochromatic normoblast" EXACT [ISBN:0721601464] synonym: "pyknotic eto enrythroblast" EXACT [ISBN:0721601464] xref: FMA:84646 is_a: CL:0000765 {is_inferred="true"} ! erythroblast intersection_of: CL:0000765 ! erythroblast intersection_of: has_part CL:0017502 ! acidophilic cytoplasm intersection_of: participates_in GO:0030263 ! apoptotic chromosome condensation relationship: develops_from CL:0000550 ! polychromatophilic erythroblast relationship: has_part CL:0017502 ! acidophilic cytoplasm relationship: participates_in GO:0030263 ! apoptotic chromosome condensation [Term] id: CL:0000553 name: megakaryocyte progenitor cell def: "The earliest cytologically identifiable precursor in the thrombocytic series. This cell is capable of endomitosis and lacks expression of hematopoieitic lineage markers (lin-negative)." [GOC:dsd, GOC:tfm, ISBN:0721601464] comment: Lineage negative is described here as CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD14-negative, CD19-negative, CD20-negative, CD56-negative, Ly6g-negative, and Ter119-negative. subset: cellxgene_subset subset: human_reference_atlas synonym: "CFU-Meg" EXACT [PMID:11722431, PMID:12482498] synonym: "colony-forming unit-megakaryocyte" EXACT [] synonym: "Meg-CFC" EXACT [PMCID:PMC1794060] synonym: "megacaryoblast" EXACT [] synonym: "megacaryocyte progenitor cell" EXACT [] synonym: "megakaryoblast" EXACT [] synonym: "megakaryocytic progenitor cell" EXACT [PMID:12482498] synonym: "MkP" EXACT [PMID:21116988] synonym: "promegacaryocyte" RELATED [] synonym: "promegakaryocyte" RELATED [] xref: BTO:0001164 xref: CALOHA:TS-0610 xref: FMA:84235 xref: MESH:D055016 is_a: CL:0000763 ! myeloid cell is_a: CL:0000839 {is_inferred="true"} ! myeloid lineage restricted progenitor cell intersection_of: CL:0000839 ! myeloid lineage restricted progenitor cell intersection_of: capable_of GO:0007113 ! endomitotic cell cycle intersection_of: capable_of GO:0030219 ! megakaryocyte differentiation intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G intersection_of: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) relationship: capable_of GO:0007113 ! endomitotic cell cycle relationship: capable_of GO:0030219 ! megakaryocyte differentiation relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G relationship: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) relationship: develops_from CL:0000050 ! megakaryocyte-erythroid progenitor cell property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000556 name: megakaryocyte def: "A large hematopoietic cell (50 to 100 micron) with a lobated nucleus. Once mature, this cell undergoes multiple rounds of endomitosis and cytoplasmic restructuring to allow platelet formation and release." [http://en.wikipedia.org/wiki/Megakaryocyte, ISBN:0721601464, MESH:D008533, PMID:31043076] comment: Megakaryocytes are reportedly CD181-positive and CD182-positive. subset: blood_and_immune_upper_slim subset: cellxgene_subset subset: human_reference_atlas synonym: "megacaryocyte" EXACT [] synonym: "megalocaryocyte" EXACT [] synonym: "megalokaryocyte" EXACT [] xref: BTO:0000843 xref: CALOHA:TS-0611 xref: FMA:83555 is_a: CL:0000763 {is_inferred="true"} ! myeloid cell disjoint_from: CL:0000764 ! erythroid lineage cell relationship: develops_from CL:0000553 ! megakaryocyte progenitor cell relationship: has_characteristic PATO:0001393 ! euploid property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000558 name: reticulocyte def: "An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds." [GOC:add, GOC:tfm, PMID:15946868, PMID:2037622] subset: blood_and_immune_upper_slim subset: cellxgene_subset xref: BTO:0001173 xref: CALOHA:TS-0864 xref: MESH:D012156 is_a: CL:0000764 {is_inferred="true"} ! erythroid lineage cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000764 ! erythroid lineage cell intersection_of: capable_of GO:0071971 ! extracellular exosome assembly intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G intersection_of: has_plasma_membrane_part PR:000001945 ! transferrin receptor protein 1 relationship: capable_of GO:0071971 ! extracellular exosome assembly relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G relationship: develops_from CL:0000552 ! orthochromatic erythroblast relationship: has_plasma_membrane_part PR:000001945 ! transferrin receptor protein 1 [Term] id: CL:0000562 name: nucleate erythrocyte def: "An erythrocyte having a nucleus." [GOC:add, GOc:tfm] synonym: "RBC" BROAD [] synonym: "red blood cell" BROAD [] is_a: CL:0000232 {is_inferred="true"} ! erythrocyte is_a: CL:0002242 ! nucleate cell intersection_of: CL:0000232 ! erythrocyte intersection_of: has_characteristic PATO:0002505 ! nucleated relationship: develops_from CL:0002421 ! nucleated reticulocyte [Term] id: CL:0000566 name: angioblastic mesenchymal cell def: "A mesenchymal stem cell capable of developing into blood vessel endothelium." [GOC:dsd, GOC:tfm, PMID:12768659] comment: These cells are reportedly CD31-positive, CD34-positive, CD144-positive, CD309-positive, and TAL1-positive. synonym: "angioblast" EXACT [] synonym: "chondroplast" EXACT [] is_a: CL:0000134 {is_inferred="true"} ! mesenchymal stem cell is_a: CL:0011026 ! progenitor cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000134 ! mesenchymal stem cell intersection_of: has_plasma_membrane_part PR:000001444 ! cadherin-5 intersection_of: has_plasma_membrane_part PR:000002112 ! vascular endothelial growth factor receptor 2 intersection_of: has_plasma_membrane_part PR:000016043 ! T-cell acute lymphocytic leukemia protein 1 relationship: develops_from CL:0000134 ! mesenchymal stem cell relationship: has_plasma_membrane_part PR:000001444 ! cadherin-5 relationship: has_plasma_membrane_part PR:000002112 ! vascular endothelial growth factor receptor 2 relationship: has_plasma_membrane_part PR:000016043 ! T-cell acute lymphocytic leukemia protein 1 [Term] id: CL:0000569 name: cardiac mesenchymal cell def: "A mesenchymal cell found in the developing heart and that develops into some part of the heart. These cells derive from intra- and extra-cardiac sources, including the endocardium, epicardium, neural crest, and second heart field." [PMID:18816864] subset: cellxgene_subset is_a: CL:0008019 ! mesenchymal cell is_a: CL:2000073 ! migratory cardiac neural crest cell intersection_of: CL:0008019 ! mesenchymal cell intersection_of: develops_into CL:0002494 ! cardiocyte relationship: develops_into CL:0002494 ! cardiocyte [Term] id: CL:0000573 name: retinal cone cell def: "One of the two photoreceptor cell types in the vertebrate retina. In cones the photopigment is in invaginations of the cell membrane of the outer segment. Cones are less sensitive to light than rods, but they provide vision with higher spatial and temporal acuity, and the combination of signals from cones with different pigments allows color vision." [MESH:D017949] subset: cellxgene_subset subset: human_reference_atlas synonym: "cone" RELATED [doi:10.1038/s41598-020-66092-9] xref: BTO:0001036 xref: CALOHA:TS-0866 xref: FMA:67748 is_a: CL:0010009 ! camera-type eye photoreceptor cell relationship: develops_from CL:0002672 ! retinal progenitor cell property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000575 name: corneal epithelial cell def: "An epithelial cell of the cornea." [GOC:tfm] subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas synonym: "epithelial cell of cornea" EXACT [FMA:70551] xref: BTO:0004298 xref: CALOHA:TS-0173 xref: FMA:70551 is_a: CL:0000076 ! squamous epithelial cell is_a: CL:0002159 ! general ecto-epithelial cell is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: CL:0000076 ! squamous epithelial cell intersection_of: part_of UBERON:0001772 ! corneal epithelium relationship: part_of UBERON:0001772 ! corneal epithelium property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000586 name: germ cell def: "The reproductive cell in multicellular organisms." [MESH:D005854] subset: cellxgene_subset xref: BTO:0000535 xref: NCIT:C12597 xref: VHOG:0001534 xref: WBbt:0006796 is_a: CL:0000039 {is_inferred="true"} ! germ line cell relationship: capable_of_part_of GO:0009566 ! fertilization [Term] id: CL:0000593 name: androgen secreting cell def: "A steroid hormone secreting cell that secretes androgen." [GOC:tfm] is_a: CL:0000174 ! steroid hormone secreting cell intersection_of: CL:0000151 ! secretory cell intersection_of: capable_of GO:0035935 ! androgen secretion relationship: capable_of GO:0035935 ! androgen secretion [Term] id: CL:0000595 name: enucleate erythrocyte def: "An erythrocyte lacking a nucleus." [GOC:add, GOC:tfm] subset: cellxgene_subset synonym: "RBC" RELATED OMO:0003000 [] synonym: "red blood cell" BROAD [] is_a: CL:0000225 ! anucleate cell is_a: CL:0000232 {is_inferred="true"} ! erythrocyte intersection_of: CL:0000232 ! erythrocyte intersection_of: has_characteristic PATO:0001405 ! anucleate relationship: develops_from CL:0002422 ! enucleated reticulocyte [Term] id: CL:0000604 name: retinal rod cell def: "One of the two photoreceptor cell types of the vertebrate retina. In rods the photopigment is in stacks of membranous disks separate from the outer cell membrane. Rods are more sensitive to light than cones, but rod mediated vision has less spatial and temporal resolution than cone vision." [MESH:D017948] subset: cellxgene_subset subset: human_reference_atlas synonym: "rod" RELATED [doi:10.1038/s41598-020-66092-9] xref: BTO:0001024 xref: CALOHA:TS-0870 xref: FMA:67747 is_a: CL:0010009 ! camera-type eye photoreceptor cell relationship: develops_from CL:0002672 ! retinal progenitor cell property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000622 name: acinar cell def: "A secretory cell that is grouped together with other cells of the same type to form grape shaped clusters known as acini (singular acinus)." [GOC:tfm, http://www.copewithcytokines.de] subset: cellxgene_subset synonym: "acinic cell" EXACT [] synonym: "acinous cell" EXACT [] xref: FMA:83625 xref: MESH:D061354 is_a: CL:0000150 ! glandular epithelial cell is_a: CL:0000154 ! protein secreting cell relationship: part_of UBERON:0009842 ! glandular acinus [Term] id: CL:0000630 name: supporting cell def: "A cell whose primary function is to support other cell types." [FB:ma, GOC:tfm] subset: cellxgene_subset synonym: "supportive cell" EXACT [] xref: BTO:0002315 is_a: CL:0000000 ! cell [Term] id: CL:0000656 name: primary spermatocyte def: "A diploid cell that has derived from a spermatogonium and can subsequently begin meiosis and divide into two haploid secondary spermatocytes." [GOC:tfm, ISBN:0721662544] xref: BTO:0001115 xref: CALOHA:TS-2194 xref: FMA:72292 is_a: CL:0000017 ! spermatocyte is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000017 ! spermatocyte intersection_of: capable_of GO:0007140 ! male meiotic nuclear division intersection_of: has_characteristic PATO:0001394 ! diploid relationship: capable_of GO:0007140 ! male meiotic nuclear division relationship: has_characteristic PATO:0001394 ! diploid [Term] id: CL:0000657 name: secondary spermatocyte def: "One of the two haploid cells into which a primary spermatocyte divides, and which in turn gives origin to spermatids." [GOC:tfm, ISBN:0721662544] xref: BTO:0000709 xref: CALOHA:TS-2195 xref: FBbt:00004941 xref: FMA:72293 is_a: CL:0000017 ! spermatocyte is_a: CL:0000255 ! eukaryotic cell is_a: CL:0000413 ! haploid cell intersection_of: CL:0000017 ! spermatocyte intersection_of: capable_of GO:0007142 ! male meiosis II intersection_of: has_characteristic PATO:0001375 ! haploid relationship: capable_of GO:0007142 ! male meiosis II relationship: develops_from CL:0000656 ! primary spermatocyte [Term] id: CL:0000667 name: collagen secreting cell def: "An extracellular matrix secreting cell that secretes collagen." [GOC:tfm] subset: cellxgene_subset is_a: CL:0000327 ! extracellular matrix secreting cell [Term] id: CL:0000670 name: primordial germ cell def: "A primordial germ cell is a diploid germ cell precursors that transiently exist in the embryo before they enter into close association with the somatic cells of the gonad and become irreversibly committed as germ cells." [GOC:tfm, PMID:1381289] subset: cellxgene_subset synonym: "gonocyte" EXACT [] synonym: "primitive germ cell" EXACT [] xref: FMA:70567 is_a: CL:0000039 {is_inferred="true"} ! germ line cell is_a: CL:0000219 {is_inferred="true"} ! motile cell intersection_of: CL:0000039 ! germ line cell intersection_of: capable_of GO:0048870 ! cell motility intersection_of: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0000922 ! embryo [Term] id: CL:0000675 name: female gamete def: "A mature sexual reproductive cell of the female germline." [GOC:tfm] is_a: CL:0000021 {is_inferred="true"} ! female germ cell is_a: CL:0000300 ! gamete [Term] id: CL:0000680 name: muscle precursor cell def: "A non-terminally differentiated cell that is capable of developing into a muscle cell." [GOC:add] subset: cellxgene_subset is_a: CL:0000055 ! non-terminally differentiated cell is_a: CL:0000255 ! eukaryotic cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0011115 ! precursor cell intersection_of: develops_into CL:0000187 ! muscle cell relationship: develops_from CL:0000222 ! mesodermal cell relationship: develops_into CL:0000187 ! muscle cell [Term] id: CL:0000696 name: PP cell def: "A cell that stores and secretes pancreatic polypeptide hormone." [GOC:tfm, JB:jb, PMID:15153415] subset: cellxgene_subset synonym: "type F enteroendocrine cell" EXACT [] xref: FMA:62938 xref: FMA:83409 is_a: CL:0000164 ! enteroendocrine cell is_a: CL:0000167 ! peptide hormone secreting cell [Term] id: CL:0000710 name: neurecto-epithelial cell def: "Epithelial cells derived from neural plate and neural crest." [GOC:tfm] comment: The term "neuroepithelial cell" is used to describe both this cell type and sensory epithelial cell (CL:0000098). synonym: "neuroepithelial cell" BROAD [] xref: BTO:0004301 xref: FMA:70557 is_a: CL:0000075 ! columnar/cuboidal epithelial cell is_a: CL:0002077 ! ecto-epithelial cell intersection_of: CL:0002077 ! ecto-epithelial cell intersection_of: develops_from CL:0000133 ! neurectodermal cell relationship: develops_from CL:0000133 ! neurectodermal cell [Term] id: CL:0000723 name: somatic stem cell def: "A stem cell that can give rise to cell types of the body other than those of the germ-line." [GO:0048103] xref: CALOHA:TS-2086 xref: MESH:D053687 is_a: CL:0000034 ! stem cell intersection_of: CL:0000034 ! stem cell intersection_of: capable_of GO:0048103 ! somatic stem cell division relationship: capable_of GO:0048103 ! somatic stem cell division [Term] id: CL:0000737 name: striated muscle cell def: "Muscle cell which has as its direct parts myofilaments organized into sarcomeres." [GOC:tfm, ISBN:0721662544] xref: BTO:0002916 xref: CALOHA:TS-2157 xref: FMA:86936 is_a: CL:0000187 ! muscle cell intersection_of: CL:0000187 ! muscle cell intersection_of: has_characteristic PATO:0001410 ! striated intersection_of: has_part GO:0030017 ! sarcomere disjoint_from: CL:0008000 ! non-striated muscle cell relationship: has_characteristic PATO:0001410 ! striated relationship: has_part GO:0030017 ! sarcomere [Term] id: CL:0000738 name: leukocyte def: "An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue." [GOC:add, GOC:tfm, ISBN:978-0-323-05290-0] subset: cellxgene_subset subset: human_reference_atlas synonym: "immune cell" RELATED [] synonym: "leucocyte" EXACT [] synonym: "white blood cell" EXACT [] xref: BTO:0000751 xref: CALOHA:TS-0549 xref: FMA:62852 xref: MESH:D007962 xref: NCIT:C12529 is_a: CL:0000219 ! motile cell is_a: CL:0000255 ! eukaryotic cell is_a: CL:0000988 {is_inferred="true"} ! hematopoietic cell is_a: CL:0002242 ! nucleate cell intersection_of: CL:0000988 ! hematopoietic cell intersection_of: capable_of GO:0001667 ! ameboidal-type cell migration intersection_of: has_characteristic PATO:0002505 ! nucleated relationship: capable_of GO:0001667 ! ameboidal-type cell migration relationship: develops_from CL:0000037 ! hematopoietic stem cell relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0002405 ! immune system property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000740 name: retinal ganglion cell def: "The set of neurons that receives neural inputs via bipolar, horizontal and amacrine cells. The axons of these cells make up the optic nerve." [GOC:dph] subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas synonym: "gangliocyte" EXACT [] synonym: "ganglion cell of retina" EXACT [] synonym: "RGC" RELATED OMO:0003000 [doi:10.1038/s41598-020-66092-9] synonym: "RGCs" RELATED OMO:0003004 [doi:10.1038/s41598-020-66092-9] xref: BTO:0001800 xref: FMA:67765 xref: MESH:D012165 is_a: CL:0000117 ! CNS neuron (sensu Vertebrata) relationship: has_soma_location UBERON:0000966 ! retina property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000746 name: cardiac muscle cell alt_id: FMA:83808 def: "Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. In mammals, the contractile fiber resembles those of skeletal muscle but are only one third as large in diameter, are richer in sarcoplasm, and contain centrally located instead of peripheral nuclei." [GOC:mtg_cardiacconduct_nov11, GOC:tfm, ISBN:0323052908, PMID:22426062, PMID:4711263] comment: This class encompasses the muscle cells responsible for heart* contraction in both vertebrates and arthropods. The ultrastucture of a wide range of arthropod heart cells has been examined including spiders, horseshoe crabs, crustaceans (see Sherman, 1973 and refs therein) and insects (see Lehmacher et al (2012) and refs therein). According to these refs, the cells participating in heart contraction in all cases are transversely striated. Insects hearts additionally contain ostial cells, also transversely striated muscle cells, but which do not participate in heart contraction. subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "cardiac muscle fiber" EXACT [GO:0048739] synonym: "cardiac myocyte" EXACT [] synonym: "cardiocyte" BROAD [] synonym: "cardiomyocyte" EXACT [] synonym: "heart muscle cell" EXACT [] xref: BTO:0001539 xref: CALOHA:TS-0115 xref: FMA:14067 xref: MESH:D032383 is_a: CL:0000737 ! striated muscle cell is_a: CL:0002494 ! cardiocyte intersection_of: CL:0000187 ! muscle cell intersection_of: has_characteristic PATO:0002478 ! transversely striated intersection_of: has_part GO:0030017 ! sarcomere intersection_of: part_of UBERON:0007100 ! primary circulatory organ intersection_of: participates_in GO:0060047 ! heart contraction relationship: develops_from CL:0000513 ! cardiac muscle myoblast relationship: has_characteristic PATO:0002478 ! transversely striated relationship: participates_in GO:0060047 ! heart contraction property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000763 name: myeloid cell def: "A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage." [GOC:add] subset: cellxgene_subset xref: BTO:0001441 xref: CALOHA:TS-0647 xref: MESH:D022423 is_a: CL:0000255 ! eukaryotic cell is_a: CL:0000988 {is_inferred="true"} ! hematopoietic cell intersection_of: CL:0000988 ! hematopoietic cell intersection_of: develops_from CL:0000049 ! common myeloid progenitor relationship: develops_from CL:0000049 ! common myeloid progenitor [Term] id: CL:0000764 name: erythroid lineage cell def: "A immature or mature cell in the lineage leading to and including erythrocytes." [GOC:add, GOC:tfm] comment: Note that in FMA erythropoietic cells are types of nucleated erythrocytes and thus don't include erythrocytes. subset: cellxgene_subset subset: human_reference_atlas synonym: "erythropoietic cell" EXACT [] xref: CALOHA:TS-0290 xref: FMA:62845 xref: FMA:83516 is_a: CL:0000763 ! myeloid cell property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000765 name: erythroblast def: "A nucleated precursor of an erythrocyte that lacks hematopoietic lineage markers." [GOC:add, ISBN:0721601464, PMID:18174176] subset: blood_and_immune_upper_slim subset: cellxgene_subset synonym: "normoblast" EXACT [] xref: BTO:0001571 xref: CALOHA:TS-0289 xref: FMA:83504 xref: MESH:D004900 is_a: CL:0000764 {is_inferred="true"} ! erythroid lineage cell is_a: CL:0011026 ! progenitor cell intersection_of: CL:0000764 ! erythroid lineage cell intersection_of: capable_of GO:0030218 ! erythrocyte differentiation intersection_of: CL:4030045 GO:0005730 ! lacks_part nucleolus intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G intersection_of: has_part GO:0005634 ! nucleus relationship: capable_of GO:0030218 ! erythrocyte differentiation relationship: CL:4030045 GO:0005730 ! lacks_part nucleolus relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G relationship: develops_from CL:0000547 ! proerythroblast relationship: has_part GO:0005634 ! nucleus [Term] id: CL:0000766 name: myeloid leukocyte def: "A cell of the monocyte, granulocyte, or mast cell lineage." [GOC:add] subset: cellxgene_subset is_a: CL:0000738 {is_inferred="true"} ! leukocyte is_a: CL:0000763 ! myeloid cell intersection_of: CL:0000738 ! leukocyte intersection_of: develops_from CL:0000049 ! common myeloid progenitor [Term] id: CL:0000783 name: multinucleated phagocyte def: "A phagocyte formed by the fusion of mononuclear phagocytes." [GOC:add, GOC:tfm] is_a: CL:0000228 ! multinucleate cell is_a: CL:0000518 {is_inferred="true"} ! phagocyte (sensu Vertebrata) intersection_of: CL:0000518 ! phagocyte (sensu Vertebrata) intersection_of: has_characteristic PATO:0001908 ! multinucleate [Term] id: CL:0000827 name: pro-T cell def: "A lymphoid progenitor cell of the T cell lineage, with some lineage specific marker expression, but not yet fully committed to the T cell lineage." [GOC:add, ISBN:0781735149] subset: cellxgene_subset synonym: "DN1 cell" NARROW [] synonym: "DN1 thymocyte" NARROW [] synonym: "pro-T lymphocyte" EXACT [] synonym: "progenitor T cell" EXACT [] synonym: "TN1 cell" NARROW [] is_a: CL:0000838 {is_inferred="true"} ! lymphoid lineage restricted progenitor cell intersection_of: CL:0000838 ! lymphoid lineage restricted progenitor cell intersection_of: capable_of GO:0030217 ! T cell differentiation relationship: capable_of GO:0030217 ! T cell differentiation relationship: develops_from CL:0000051 ! common lymphoid progenitor [Term] id: CL:0000837 name: hematopoietic multipotent progenitor cell def: "A hematopoietic multipotent progenitor cell is multipotent, but not capable of long-term self-renewal. These cells are characterized as lacking lineage cell surface markers and being CD34-positive in both mice and humans." [GOC:add, GOC:tfm, PMID:19022770] comment: Markers differ between mouse and human. subset: blood_and_immune_upper_slim subset: cellxgene_subset subset: human_reference_atlas synonym: "hemopoietic progenitor cell" EXACT [] synonym: "MPP" EXACT [] xref: BTO:0000725 xref: CALOHA:TS-0448 is_a: CL:0000255 ! eukaryotic cell is_a: CL:0008001 ! hematopoietic precursor cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000988 ! hematopoietic cell intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 intersection_of: CL:4030046 PR:000001869 ! lacks_plasma_membrane_part interleukin-7 receptor subunit alpha intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G intersection_of: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) intersection_of: has_characteristic PATO:0001402 ! multipotent intersection_of: has_plasma_membrane_part PR:000001003 ! CD34 molecule disjoint_from: CL:0002032 ! hematopoietic oligopotent progenitor cell relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 relationship: CL:4030046 PR:000001869 ! lacks_plasma_membrane_part interleukin-7 receptor subunit alpha relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G relationship: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) relationship: develops_from CL:0000037 ! hematopoietic stem cell relationship: has_characteristic PATO:0001402 ! multipotent relationship: has_plasma_membrane_part PR:000001003 ! CD34 molecule property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000838 name: lymphoid lineage restricted progenitor cell def: "A progenitor cell restricted to the lymphoid lineage." [GOC:add, GOC:tfm] comment: Note that this is a class of cell types, not an identified single cell type. subset: cellxgene_subset synonym: "lymphoid progenitor cell" BROAD [] xref: BTO:0004731 xref: CALOHA:TS-2025 xref: FMA:70338 is_a: CL:0002031 {is_inferred="true"} ! hematopoietic lineage restricted progenitor cell is_a: CL:0011026 ! progenitor cell intersection_of: CL:0002031 ! hematopoietic lineage restricted progenitor cell intersection_of: capable_of GO:0030098 ! lymphocyte differentiation disjoint_from: CL:0000839 ! myeloid lineage restricted progenitor cell relationship: capable_of GO:0030098 ! lymphocyte differentiation [Term] id: CL:0000839 name: myeloid lineage restricted progenitor cell def: "A progenitor cell restricted to the myeloid lineage." [GOC:add, GOC:tfm, PMID:19022770] comment: Note that this is a class of cell types, not an identified single cell type. subset: cellxgene_subset subset: human_reference_atlas synonym: "myeloid progenitor cell" BROAD [] xref: BTO:0004730 xref: CALOHA:TS-2099 xref: FMA:70339 is_a: CL:0002031 {is_inferred="true"} ! hematopoietic lineage restricted progenitor cell is_a: CL:0011026 ! progenitor cell intersection_of: CL:0002031 ! hematopoietic lineage restricted progenitor cell intersection_of: capable_of GO:0030099 ! myeloid cell differentiation relationship: capable_of GO:0030099 ! myeloid cell differentiation property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000842 name: mononuclear cell def: "A leukocyte with a single non-segmented nucleus in the mature form." [GOC:add] subset: blood_and_immune_upper_slim subset: cellxgene_subset synonym: "mononuclear leukocyte" EXACT [] synonym: "peripheral blood mononuclear cell" NARROW [] xref: BTO:0000878 xref: CALOHA:TS-0768 xref: FMA:86713 is_a: CL:0000226 ! single nucleate cell is_a: CL:0000738 {is_inferred="true"} ! leukocyte intersection_of: CL:0000738 ! leukocyte intersection_of: has_characteristic PATO:0001407 ! mononucleate [Term] id: CL:0000850 name: serotonergic neuron def: "A neuron that releases serotonin as a neurotransmitter." [SANBI:mhl] synonym: "5-HT neuron" EXACT [] synonym: "5-hydroxytryptamine neuron" EXACT [] synonym: "serotinergic neuron" RELATED [] xref: FBbt:00005133 xref: MESH:D059326 xref: WBbt:0006837 is_a: CL:0000458 ! serotonin secreting cell is_a: CL:0000540 ! neuron intersection_of: CL:0000540 ! neuron intersection_of: capable_of GO:0060096 ! serotonin secretion, neurotransmission relationship: capable_of GO:0060096 ! serotonin secretion, neurotransmission [Term] id: CL:0000988 name: hematopoietic cell def: "A cell of a hematopoietic lineage." [GO_REF:0000031, GOC:add] subset: cellxgene_subset synonym: "haematopoietic cell" EXACT [] synonym: "haemopoietic cell" EXACT [] synonym: "hemopoietic cell" EXACT [] xref: BTO:0000574 xref: CALOHA:TS-2017 xref: FMA:70366 xref: FMA:83598 is_a: CL:0000000 ! cell [Term] id: CL:0001035 name: bone cell def: "A connective tissue cell found in bone." [GO_REF:0000034, GOC:add] subset: general_cell_types_upper_slim subset: human_reference_atlas is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: part_of UBERON:0001474 ! bone element relationship: part_of UBERON:0001474 ! bone element property_value: RO:0002175 NCBITaxon:9606 property_value: term:contributor https://orcid.org/0000-0001-9990-8331 creation_date: 2011-11-16T04:28:16Z [Term] id: CL:0001060 name: hematopoietic oligopotent progenitor cell, lineage-negative def: "A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities. Cell lacks hematopoeitic lineage markers." [GOC:tfm, PMID:19022770] is_a: CL:0002032 ! hematopoietic oligopotent progenitor cell intersection_of: CL:0002032 ! hematopoietic oligopotent progenitor cell intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G intersection_of: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) intersection_of: has_characteristic PATO:0001401 ! oligopotent relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G relationship: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-01-06T03:43:27Z [Term] id: CL:0001066 name: erythroid progenitor cell, mammalian def: "A progenitor cell committed to the erythroid lineage. This cell is ter119-positive but lacks expression of other hematopoietic lineage markers (lin-negative)." [GOC:add, ISBN:0721601464] subset: cellxgene_subset synonym: "BFU-E" RELATED OMO:0003000 [] synonym: "blast forming unit erythroid" RELATED [] synonym: "burst forming unit erythroid" RELATED [] synonym: "CFU-E" RELATED OMO:0003000 [] synonym: "colony forming unit erythroid" RELATED [] synonym: "erythroid stem cell" RELATED [] xref: BTO:0004911 is_a: CL:0000038 ! erythroid progenitor cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000038 ! erythroid progenitor cell intersection_of: capable_of GO:0030218 ! erythrocyte differentiation intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G intersection_of: has_plasma_membrane_part PR:000001945 ! transferrin receptor protein 1 relationship: capable_of GO:0030218 ! erythrocyte differentiation relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G relationship: has_plasma_membrane_part PR:000001945 ! transferrin receptor protein 1 [Term] id: CL:0002031 name: hematopoietic lineage restricted progenitor cell def: "A hematopoietic progenitor cell that is capable of developing into only one lineage of hematopoietic cells." [GOC:tfm, PMID:19022770] subset: blood_and_immune_upper_slim is_a: CL:0000255 ! eukaryotic cell is_a: CL:0008001 ! hematopoietic precursor cell intersection_of: CL:0000988 ! hematopoietic cell intersection_of: has_characteristic PATO:0001400 ! unipotent disjoint_from: CL:0002032 ! hematopoietic oligopotent progenitor cell relationship: develops_from CL:0002032 ! hematopoietic oligopotent progenitor cell relationship: has_characteristic PATO:0001400 ! unipotent property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-01-06T03:43:20Z [Term] id: CL:0002032 name: hematopoietic oligopotent progenitor cell def: "A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities." [GOC:tfm, https://orcid.org/0000-0001-5208-3432, PMID:19022770] comment: This cell type is intended to be compatible with any vertebrate hematopoietic oligopotent progenitor cell. For mammalian hematopoietic oligopotent progenitor cells known to be lineage-negative, please use the term 'hematopoietic oligopotent progenitor cell' (CL_0001060). subset: blood_and_immune_upper_slim is_a: CL:0000255 ! eukaryotic cell is_a: CL:0008001 ! hematopoietic precursor cell intersection_of: CL:0000988 ! hematopoietic cell intersection_of: has_characteristic PATO:0001401 ! oligopotent relationship: develops_from CL:0000837 ! hematopoietic multipotent progenitor cell relationship: has_characteristic PATO:0001401 ! oligopotent property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-01-06T03:43:27Z [Term] id: CL:0002064 name: pancreatic acinar cell def: "A secretory cell found in pancreatic acini that secretes digestive enzymes and mucins. This cell is a typical zymogenic cell, have a basal nucleus and basophilic cytoplasm consisting of regular arrays of granular endoplasmic reticulum with mitochondria and dense secretory granules." [GOC:tfm, http://www.copewithcytokines.de/cope.cgi?key=pancreatic%20acinar%20cells, ISBN:0517223651, PMID:20395539] subset: cellxgene_subset subset: human_reference_atlas synonym: "acinar cell of pancreas" EXACT [] xref: BTO:0000028 xref: CALOHA:TS-0737 xref: FMA:63032 is_a: CL:0000622 {is_inferred="true"} ! acinar cell is_a: CL:1001599 ! pancreas exocrine glandular cell intersection_of: CL:0000622 ! acinar cell intersection_of: part_of UBERON:0001263 ! pancreatic acinus relationship: has_part GO:0042589 ! zymogen granule membrane relationship: part_of UBERON:0001263 ! pancreatic acinus property_value: RO:0002175 NCBITaxon:9606 property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-06-24T03:16:29Z [Term] id: CL:0002067 name: type A enteroendocrine cell def: "An enteroendocrine cell that produces glucagon." [GOC:tfm, ISBN:0412046911] xref: FMA:62939 is_a: CL:0000164 ! enteroendocrine cell is_a: CL:0000170 ! glucagon secreting cell intersection_of: CL:0000164 ! enteroendocrine cell intersection_of: capable_of GO:0070091 ! glucagon secretion property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-10T10:48:54Z [Term] id: CL:0002068 name: Purkinje myocyte def: "Specialized cardiac myocyte that is subendocardially interspersed with the regular cardiac muscle cell. They are uninucleate cylindrical cells, associated end-to-end in long rows, continue from the node to the atrioventricular bundle; relatively short compared to ordinary myocytes but are nearly twice their diameter." [FMA:0412046911, GOC:tfm, PMID:19939742] subset: human_reference_atlas synonym: "myocytus conducens cardiacus" EXACT [] synonym: "Purkinje cell fiber" EXACT [] synonym: "Purkinje muscle cell" EXACT [] xref: BTO:0001032 xref: FMA:14146 is_a: CL:0002086 ! specialized cardiac myocyte property_value: RO:0002175 NCBITaxon:9606 property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-06-28T08:36:15Z [Term] id: CL:0002072 name: nodal myocyte def: "A specialized cardiac myocyte in the sinoatrial and atrioventricular nodes. The cell is slender and fusiform confined to the nodal center, circumferentially arranged around the nodal artery." [FMA:67101, GOC:tfm] synonym: "cardiac pacemaker cell" EXACT [GOC:pr] synonym: "myocytus nodalis" EXACT [] synonym: "P cell" EXACT [] synonym: "pacemaker cell" BROAD [] xref: BTO:0004190 xref: FMA:67101 is_a: CL:0002086 ! specialized cardiac myocyte property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-06-29T11:41:37Z [Term] id: CL:0002073 name: transitional myocyte def: "Specialized cardiac myocyte which is in the internodal tract and atrioventricular node. The cell is more slender than ordinary atrial myocytes and has more myofibrils than nodal myocytes." [FMA:67142, GOC:tfm] xref: FMA:67142 is_a: CL:0002086 ! specialized cardiac myocyte property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-06-29T02:39:32Z [Term] id: CL:0002074 name: myocardial endocrine cell def: "The myoendocrine cellis a specialized myocyte localized mainly in the right and left atrial appendages, and also scattered within other areas of the atria and along the conductive system in the ventricular septum. The most conspicuous feature distinguishing myoendocrine cells from other atrial myoctyes is the presence of membane-bounded secretory granules (these granules contain precursor of cardiodilatins or atrial natriuretic polypeptides)." [FMA:67111, GOC:tfm] xref: FMA:67111 is_a: CL:0000163 ! endocrine cell is_a: CL:0002086 ! specialized cardiac myocyte property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-06-29T11:50:47Z [Term] id: CL:0002076 name: endo-epithelial cell def: "An epithelial cell derived from endoderm." [FMA:69075, GOC:tfm] xref: FMA:69075 is_a: CL:0000066 ! epithelial cell is_a: UBERON:0004119 ! endoderm-derived structure relationship: develops_from CL:0000223 ! endodermal cell property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-06-29T03:38:14Z [Term] id: CL:0002077 name: ecto-epithelial cell def: "An epithelial cell derived from ectoderm." [FMA:69074, GOC:tfm] xref: FMA:69074 xref: ZFA:0009385 {sssom:mapping_justification="vocab:UnspecifiedMatching"} is_a: CL:0000066 ! epithelial cell is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:0000066 ! epithelial cell intersection_of: develops_from CL:0000221 ! ectodermal cell relationship: develops_from CL:0000221 ! ectodermal cell property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-06-29T03:38:22Z [Term] id: CL:0002078 name: meso-epithelial cell def: "Epithelial cell derived from mesoderm or mesenchyme." [FMA:69076, GOC:tfm] synonym: "epithelial mesenchymal cell" EXACT [] xref: FMA:69076 is_a: CL:0000066 ! epithelial cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000066 ! epithelial cell intersection_of: develops_from CL:0000222 ! mesodermal cell relationship: develops_from CL:0000222 ! mesodermal cell property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-06-29T03:49:14Z [Term] id: CL:0002079 name: pancreatic ductal cell def: "Epithelial cell found in the ducts of the pancreas. This cell type contributes to the high luminal pH." [FMA:63099, GOC:tfm, PMID:14740223] subset: cellxgene_subset subset: human_reference_atlas xref: FMA:63099 is_a: CL:0000069 ! branched duct epithelial cell is_a: CL:1001433 ! epithelial cell of exocrine pancreas intersection_of: CL:0000083 ! epithelial cell of pancreas intersection_of: capable_of GO:0015106 ! bicarbonate transmembrane transporter activity intersection_of: part_of UBERON:0001064 ! ventral pancreatic duct relationship: capable_of GO:0015106 ! bicarbonate transmembrane transporter activity relationship: part_of UBERON:0001064 ! ventral pancreatic duct property_value: RO:0002175 NCBITaxon:9606 property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-06-30T08:49:43Z [Term] id: CL:0002080 name: pancreatic centro-acinar cell def: "A cubodial epithelial cell that is continuous with the lining of intercalated ducts that drain the acinus. This cell type secretes a high pH solution to aid in activation of zymogens, and can differentiate into endocrine and exocrine pancreatic cell types." [GOC:tfm, PMID:12142741, PMID:20018761, PMID:8185160] subset: human_reference_atlas synonym: "centroacinar cell of Langerhans" EXACT [] synonym: "pancreatic centroacinar cell" EXACT [] xref: FMA:62455 is_a: CL:1001433 ! epithelial cell of exocrine pancreas intersection_of: CL:0000083 ! epithelial cell of pancreas intersection_of: capable_of GO:0015106 ! bicarbonate transmembrane transporter activity intersection_of: part_of UBERON:0001263 ! pancreatic acinus relationship: capable_of GO:0015106 ! bicarbonate transmembrane transporter activity relationship: part_of UBERON:0001263 ! pancreatic acinus property_value: RO:0002175 NCBITaxon:9606 property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-06-30T08:49:52Z [Term] id: CL:0002086 name: specialized cardiac myocyte def: "A cardiac myocyte that is an excitable cells in the myocardium, specifically in the conducting system of heart." [FMA:67968, GOC:tfm] xref: FMA:67968 is_a: CL:0000746 ! cardiac muscle cell property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-07-21T01:33:38Z [Term] id: CL:0002087 name: nongranular leukocyte def: "A leukocyte that lacks granules." [GOC:tfm] subset: blood_and_immune_upper_slim synonym: "agranular leukocyte" EXACT [] xref: FMA:62855 is_a: CL:0000738 {is_inferred="true"} ! leukocyte intersection_of: CL:0000738 ! leukocyte intersection_of: CL:4030045 GO:0030141 ! lacks_part secretory granule relationship: CL:4030045 GO:0030141 ! lacks_part secretory granule property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-07-22T11:30:33Z [Term] id: CL:0002088 name: interstitial cell of Cajal def: "This is a cell found in the gastrointestinal tract of mammals and serves as a pacemaker that triggers gut contraction. ICCs mediate inputs from the enteric nervous system to smooth muscle cells and are thought to be the cells from which gastrointestinal stromal tumors (GISTs) arise." [GOC:tfm, PMID:16460275, PMID:19520112] comment: Some argue this cell type is of mesenchymal origin. subset: cellxgene_subset subset: human_reference_atlas synonym: "ICC" EXACT [] synonym: "intestinal pacemaker cell" EXACT [GOC:pr] xref: BTO:0003914 xref: FMA:86573 is_a: CL:0000710 {is_inferred="true"} ! neurecto-epithelial cell intersection_of: CL:0000710 ! neurecto-epithelial cell intersection_of: capable_of GO:0043134 ! regulation of hindgut contraction relationship: capable_of GO:0043134 ! regulation of hindgut contraction property_value: RO:0002175 NCBITaxon:9606 property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-07-22T03:26:00Z [Term] id: CL:0002092 name: bone marrow cell def: "A cell found in the bone marrow. This can include fibroblasts, macrophages, adipocytes, osteoblasts, osteoclasts, endothelial cells and hematopoietic cells." [GOC:tfm, ISBN:0618947256] comment: MH consider whether bone marrow cells are bone cells in the structural sense vs. being part of bone organ sense. subset: cellxgene_subset xref: BTO:0004850 xref: FMA:83621 xref: MESH:D001854 is_a: CL:0001035 {is_inferred="true"} ! bone cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0001035 ! bone cell intersection_of: part_of UBERON:0002371 ! bone marrow relationship: part_of UBERON:0002371 ! bone marrow property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-07-22T04:48:15Z [Term] id: CL:0002095 name: hilus cell of ovary def: "A cell in the hilum of the ovary that produces androgens." [GOC:tfm, ISBN:068340007X] subset: human_reference_atlas synonym: "hilar cell of ovary" EXACT [] xref: FMA:18710 is_a: CL:0000593 ! androgen secreting cell is_a: CL:0002132 ! stromal cell of ovary property_value: RO:0002175 NCBITaxon:9606 property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-08-23T11:18:18Z [Term] id: CL:0002132 name: stromal cell of ovary def: "A stomal cell of the ovary" [GOC:tfm] subset: cellxgene_subset synonym: "ovarian stromal cell" EXACT [GOC:cjm] xref: FMA:72299 is_a: CL:0000499 ! stromal cell intersection_of: CL:0000499 ! stromal cell intersection_of: part_of UBERON:0000992 ! ovary relationship: part_of UBERON:0000992 ! ovary property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-08-23T12:10:31Z [Term] id: CL:0002139 name: endothelial cell of vascular tree def: "An endothelial cell of the vascular tree, which includes blood vessels and lymphatic vessels." [GOC:dsd, GOC:tfm, PMID:12768659] comment: These cells are reportedly CD31-positive, CD34-positive, CD144-positive, TAL1-positive. subset: cellxgene_subset synonym: "cubodial endothelial cell of vascular tree" NARROW [] synonym: "vascular endothelial cell" EXACT [] xref: BTO:0001854 xref: CALOHA:TS-1106 xref: FMA:67755 is_a: CL:0000115 ! endothelial cell property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-08-24T02:06:40Z [Term] id: CL:0002144 name: capillary endothelial cell def: "An endothelial cell found in capillaries." [GOC:tfm] subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0004956 xref: CALOHA:TS-0112 xref: FMA:67756 is_a: CL:2000008 ! microvascular endothelial cell intersection_of: CL:0000071 ! blood vessel endothelial cell intersection_of: part_of UBERON:0001915 ! endothelium of capillary relationship: part_of UBERON:0001915 ! endothelium of capillary property_value: RO:0002175 NCBITaxon:9606 property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-08-24T10:15:00Z [Term] id: CL:0002149 name: epithelial cell of uterus def: "An epithelial cell of the uterus." [GOC:tfm] subset: cellxgene_subset xref: FMA:256161 is_a: CL:0002076 {is_inferred="true"} ! endo-epithelial cell intersection_of: CL:0002076 ! endo-epithelial cell intersection_of: part_of UBERON:0000995 ! uterus relationship: part_of UBERON:0000995 ! uterus property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-08-24T10:45:54Z [Term] id: CL:0002159 name: general ecto-epithelial cell def: "Epithelial cells derived from general body ectoderm and ectoderm placodes." [GOC:tfm] xref: FMA:70556 is_a: CL:0002077 ! ecto-epithelial cell property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-08-26T08:31:08Z [Term] id: CL:0002178 name: epithelial cell of stomach def: "An epithelial cell found in the lining of the stomach." [GOC:tfm] xref: FMA:62948 is_a: CL:0002251 {is_inferred="true"} ! epithelial cell of alimentary canal intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0000945 ! stomach relationship: part_of UBERON:0000945 ! stomach property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-08-25T03:22:08Z [Term] id: CL:0002180 name: mucous cell of stomach def: "A mucous cell in the epithelium of the stomach." [GOC:tfm] xref: FMA:63464 is_a: CL:0002659 ! glandular cell of stomach intersection_of: CL:0002178 ! epithelial cell of stomach intersection_of: part_of UBERON:0001199 ! mucosa of stomach relationship: part_of UBERON:0001199 ! mucosa of stomach property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-08-25T03:38:51Z [Term] id: CL:0002183 name: stem cell of gastric gland def: "A stomach epithelial cell that is olumnar in form with a few short apical microvilli; relatively undifferentiated mitotic cell from which other types of gland are derived; few in number, situated in the isthmus region of the gland and base of the gastric pit." [GOC:tfm, ISBN:0517223651] xref: FMA:62953 is_a: CL:0000048 {is_inferred="true"} ! multi fate stem cell is_a: CL:0000152 ! exocrine cell is_a: CL:0002180 ! mucous cell of stomach intersection_of: CL:0000048 ! multi fate stem cell intersection_of: part_of UBERON:0000325 ! gastric gland relationship: part_of UBERON:0000325 ! gastric gland property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-08-25T03:57:08Z [Term] id: CL:0002195 name: hepatic stem cell def: "A stem cell that can give rise to the cells of the liver. The term usually refers to the self-renewing pool of hepatocyte precursors in the adult liver (differently from 'hepatoblast', often used for fetal precursors of hepatocytes)." [GOC:tfm, PMID:26798363] synonym: "HpSC" RELATED OMO:0003000 [PMID:18442648] xref: FMA:86577 is_a: CL:0000048 {is_inferred="true"} ! multi fate stem cell is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: CL:0000048 ! multi fate stem cell intersection_of: part_of UBERON:0002107 ! liver relationship: part_of UBERON:0002107 ! liver property_value: seeAlso "https://github.com/obophenotype/cell-ontology/issues/800" xsd:string property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-08-30T02:00:42Z [Term] id: CL:0002222 name: vertebrate lens cell def: "A cell comprising the transparent, biconvex body separating the posterior chamber and vitreous body, and constituting part of the refracting mechanism of the mammalian eye." [GOC:tfm, ISBN:0721662544] subset: eye_upper_slim xref: FMA:70950 is_a: CL:0000066 ! epithelial cell is_a: CL:0000306 ! crystallin accumulating cell is_a: UBERON:0004121 ! ectoderm-derived structure relationship: part_of UBERON:0000965 ! lens of camera-type eye property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-07T10:38:03Z [Term] id: CL:0002224 name: lens epithelial cell def: "A cell of the cuboidal epithelium that covers the lens. The cells of the lens epithelium regulate most of the homeostatic functions of the lens. As ions, nutrients, and liquid enter the lens from the aqueous humor, Na+/K+ ATPase pumps in the lens epithelial cells pump ions out of the lens to maintain appropriate lens osmolarity and volume, with equatorially positioned lens epithelium cells contributing most to this current. The activity of the Na+/K+ ATPases keeps water and current flowing through the lens from the poles and exiting through the equatorial regions. The cells of the lens epithelium also serve as the progenitors for new lens fibers. It constantly lays down fibers in the embryo, fetus, infant, and adult, and continues to lay down fibers for lifelong growth." [GOC:tfm, http://en.wikipedia.org/wiki/Lens_%28anatomy%29#Lens_epithelium, ISBN:0721662544] subset: cellxgene_subset subset: human_reference_atlas xref: FMA:67559 is_a: CL:0000075 {is_inferred="true"} ! columnar/cuboidal epithelial cell is_a: CL:0002222 ! vertebrate lens cell intersection_of: CL:0000075 ! columnar/cuboidal epithelial cell intersection_of: part_of UBERON:0001803 ! epithelium of lens relationship: part_of UBERON:0001803 ! epithelium of lens property_value: RO:0002175 NCBITaxon:9606 property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-07T10:45:47Z [Term] id: CL:0002240 name: marrow fibroblast def: "A fibroblast in the bone marrow." [GOC:tfm] xref: FMA:84377 is_a: CL:0000057 ! fibroblast is_a: CL:0002092 ! bone marrow cell intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0002371 ! bone marrow property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-07T02:25:18Z [Term] id: CL:0002241 name: pulmonary interstitial fibroblast def: "A fibroblasts found in interstitial spaces in the pulmonary tract. Greater numbers of these cells are found in idiopathic pulmonary fibrosis." [GOC:tfm] subset: cellxgene_subset synonym: "pulmonary myofibroblast" EXACT [] synonym: "pulmonary septal cell" EXACT [] xref: FMA:84467 is_a: CL:0000057 {is_inferred="true"} ! fibroblast is_a: CL:4030031 ! interstitial cell intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0001004 ! respiratory system intersection_of: part_of UBERON:0005169 ! interstitial tissue relationship: part_of UBERON:0001004 ! respiratory system property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-07T02:29:38Z [Term] id: CL:0002242 name: nucleate cell def: "A cell containing at least one nucleus." [GOC:tfm] xref: FMA:67513 is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: has_characteristic PATO:0002505 ! nucleated relationship: has_characteristic PATO:0002505 ! nucleated property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-07T03:32:33Z [Term] id: CL:0002243 name: smooth muscle cell of sphincter of pupil def: "A circular smooth muscle cell of the iris, innervated by the ciliary nerves (parasympathetic), and acting to contract the pupil. This muscle cell derives from neuroectoderm. This smooth muscle cell results from transformation of epithelial cells to smooth muscle cells." [GOC:tfm, ISBN:0721662544, ISBN:0721694128] subset: cellxgene_subset synonym: "smooth muscle fiber of sphincter of pupil" EXACT [] synonym: "smooth muscle fibre of sphincter of pupil" RELATED [] xref: FMA:70611 is_a: CL:0000358 {is_inferred="true"} ! sphincter associated smooth muscle cell is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0001607 ! sphincter pupillae relationship: develops_from CL:0000133 ! neurectodermal cell relationship: part_of UBERON:0001607 ! sphincter pupillae property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-08T08:53:42Z [Term] id: CL:0002246 name: peripheral blood stem cell def: "A hematopoeitic stem cell found in the blood. Normally found in very limited numbers in the peripheral circulation (less than 0.1% of all nucleated cells)." [GOC:tfm] synonym: "PBSC" EXACT [] xref: BTO:0002669 xref: FMA:86711 xref: MESH:D000072916 is_a: CL:0000037 {is_inferred="true"} ! hematopoietic stem cell is_a: CL:0000080 ! circulating cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000037 ! hematopoietic stem cell intersection_of: part_of UBERON:0000178 ! blood relationship: part_of UBERON:0000178 ! blood property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-07T03:57:09Z [Term] id: CL:0002251 name: epithelial cell of alimentary canal def: "An epithelial cell of the musculomembranous digestive tube extending from the mouth to the anus." [GOC:tfm, ISBN:0721662544] is_a: CL:0002076 ! endo-epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0001555 ! digestive tract relationship: part_of UBERON:0001555 ! digestive tract property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-08T09:26:53Z [Term] id: CL:0002252 name: epithelial cell of esophagus def: "An epithelial cell of the esophagus." [GOC:tfm] subset: cellxgene_subset xref: FMA:63071 is_a: CL:0002251 {is_inferred="true"} ! epithelial cell of alimentary canal intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0001043 ! esophagus relationship: part_of UBERON:0001043 ! esophagus property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-08T09:28:20Z [Term] id: CL:0002253 name: epithelial cell of large intestine def: "An epithelial cell of the large intestine." [GOC:tfm] subset: cellxgene_subset synonym: "epithelial cell of colon" RELATED [] xref: BTO:0004297 xref: FMA:256157 is_a: CL:0002563 {is_inferred="true"} ! intestinal epithelial cell intersection_of: CL:0002563 ! intestinal epithelial cell intersection_of: part_of UBERON:0000059 ! large intestine relationship: part_of UBERON:0000059 ! large intestine property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-08T09:28:22Z [Term] id: CL:0002254 name: epithelial cell of small intestine def: "An epithelial cell of the small intestine." [GOC:tfm] subset: cellxgene_subset xref: FMA:256159 is_a: CL:0002563 {is_inferred="true"} ! intestinal epithelial cell intersection_of: CL:0002563 ! intestinal epithelial cell intersection_of: part_of UBERON:0002108 ! small intestine relationship: part_of UBERON:0002108 ! small intestine property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-08T09:41:46Z [Term] id: CL:0002255 name: stromal cell of endometrium def: "A stromal cell of the endometrium that is fibroblastic in appearance. During decidualization this cell may differentiate into a decidual stromal cell." [https://doi.org/10.1038/s41591-020-1040-z, PMID:11331626, PMID:30013421, PMID:30309298, Wiki:Decidualization&oldid=908981933#Endometrial_stromal_cells_(ESCs)] subset: human_reference_atlas synonym: "endometrial stromal cell" EXACT [] synonym: "endometrial stromal fibroblast" EXACT [PMID:30309298] xref: CALOHA:TS-1266 xref: FMA:86490 is_a: CL:0000499 {is_inferred="true"} ! stromal cell intersection_of: CL:0000499 ! stromal cell intersection_of: part_of UBERON:0001295 ! endometrium relationship: has_potential_to_directly_develop_into CL:2000002 ! decidual cell relationship: part_of UBERON:0002337 ! endometrial stroma property_value: RO:0002175 NCBITaxon:9606 property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-08T09:50:04Z [Term] id: CL:0002262 name: endothelial cell of sinusoid def: "An endothelial cell that lines any of the venous cavities through which blood passes in various glands and organs such as the spleen and liver." [GOC:tfm, ISBN:0618947256] subset: cellxgene_subset subset: human_reference_atlas xref: FMA:63134 is_a: CL:0000115 ! endothelial cell intersection_of: CL:0000115 ! endothelial cell intersection_of: part_of UBERON:0003909 ! sinusoid relationship: part_of UBERON:0003909 ! sinusoid property_value: RO:0002175 NCBITaxon:9606 property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-14T10:57:26Z [Term] id: CL:0002264 name: type A cell of stomach def: "A type of enteroendocrine cell found in the stomach that secretes glucagon." [GOC:tfm] xref: FMA:83411 is_a: CL:0002067 ! type A enteroendocrine cell is_a: CL:0002659 ! glandular cell of stomach intersection_of: CL:0002067 ! type A enteroendocrine cell intersection_of: part_of UBERON:0000945 ! stomach property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-10T10:54:42Z [Term] id: CL:0002265 name: type D cell of colon def: "A D cell located in the colon." [GOC:tfm] synonym: "colon D-cell" EXACT [] synonym: "colonic delta cell" EXACT [] synonym: "delta cell of colon" EXACT [] xref: FMA:268744 is_a: CL:0000502 ! type D enteroendocrine cell is_a: CL:0009042 ! enteroendocrine cell of colon intersection_of: CL:0000502 ! type D enteroendocrine cell intersection_of: part_of UBERON:0001155 ! colon property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-10T11:37:35Z [Term] id: CL:0002266 name: type D cell of small intestine def: "A type D cell of the small intestine." [GOC:tfm] synonym: "delta cell of small intestine" EXACT [] synonym: "small intestine D-cell" EXACT [] synonym: "small intestine delta cell" EXACT [] xref: FMA:268736 is_a: CL:0000502 ! type D enteroendocrine cell is_a: CL:0009006 ! enteroendocrine cell of small intestine intersection_of: CL:0000502 ! type D enteroendocrine cell intersection_of: part_of UBERON:0002108 ! small intestine property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-10T01:34:22Z [Term] id: CL:0002267 name: type D cell of stomach def: "A type D cell found in the stomach." [GOC:tfm] synonym: "delta cell of stomach" EXACT [] synonym: "stomach D-cell" EXACT [] synonym: "stomach delta cell" EXACT [] xref: FMA:83410 is_a: CL:0000502 ! type D enteroendocrine cell is_a: CL:0002659 ! glandular cell of stomach intersection_of: CL:0000502 ! type D enteroendocrine cell intersection_of: part_of UBERON:0000945 ! stomach property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-10T01:36:03Z [Term] id: CL:0002275 name: pancreatic PP cell def: "A PP cell located in the islets of the pancreas." [GOC:tfm] comment: The term PP cell of pancreatic acinus was obsoleted due to a lack of evidence, making PP cell of pancreatic islets synonymous with pancreatic PP cell. subset: cellxgene_subset subset: human_reference_atlas synonym: "pancreatic polypeptide-secreting cell" EXACT [] synonym: "PP cell of pancreatic islet" EXACT [] synonym: "PP-cell of pancreatic islet" EXACT [] xref: BTO:0000805 xref: FMA:70588 xref: MESH:D050418 is_a: CL:0000696 ! PP cell is_a: CL:0008024 ! pancreatic endocrine cell intersection_of: CL:0000696 ! PP cell intersection_of: part_of UBERON:0000006 ! islet of Langerhans intersection_of: part_of UBERON:0001264 ! pancreas relationship: part_of UBERON:0000006 ! islet of Langerhans property_value: RO:0002175 NCBITaxon:9606 property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-10T03:30:31Z [Term] id: CL:0002308 name: epithelial cell of skin gland def: "An epithelial cell of a skin gland." [GOC:tfm] synonym: "epithelial cell of gland of skin" EXACT [] xref: FMA:70657 is_a: CL:0002159 ! general ecto-epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0002419 ! skin gland relationship: part_of UBERON:0002419 ! skin gland property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-14T12:00:07Z [Term] id: CL:0002319 name: neural cell def: "A cell that is part of the nervous system." [GOC:tfm, ISBN:0618947256] subset: cellxgene_subset xref: CALOHA:TS-2040 xref: FMA:70333 is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: part_of UBERON:0001016 ! nervous system relationship: part_of UBERON:0001016 ! nervous system property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-15T01:34:57Z [Term] id: CL:0002320 name: connective tissue cell def: "A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone." [GOC:tfm, ISBN:0618947256] subset: cellxgene_subset xref: CALOHA:TS-2096 xref: FMA:63875 xref: MESH:D003239 is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: part_of UBERON:0002384 ! connective tissue relationship: part_of UBERON:0002384 ! connective tissue property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-15T03:01:54Z [Term] id: CL:0002321 name: embryonic cell (metazoa) def: "A cell of the embryo." [FMA:0618947256] xref: CALOHA:TS-0263 xref: FMA:82840 xref: https://cellxgene.cziscience.com/cellguide/CL_0002321 xref: WBbt:0007028 xref: ZFA:0007089 {sssom:mapping_justification="vocab:UnspecifiedMatching"} is_a: CL:0000000 ! cell property_value: term:contributor https://orcid.org/0000-0003-1980-3228 property_value: term:description "Embryonic cells in metazoans, which include all multicellular animals, are biological units in their earliest developmental stages from conception until the organism is fully formed. \nThey are derived from a fertilized egg, which undergoes a series of cell divisions to produce a multicellular organism. During the early phases of embryonic development, these cells exhibit pluripotency, meaning they possess the potential to differentiate into a diverse array of specialized cell types that constitute different body tissues and structures. \nThe balance between cell proliferation and differentiation in embryonic cells is crucial for successful development. When cells continue to divide without differentiating, overgrowth may occur leading to conditions such as teratomas (tumors of embryonic cells). Conversely, if cell differentiation proceeds at the expense of cell proliferation, developmental anomalies could occur regarding size or mass of the organism or its parts.\n\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)" xsd:string {xref="DOI:10.1002/iub.1404", xref="DOI:10.1093/molehr/gan048", xref="https://www.ncbi.nlm.nih.gov/books/NBK9906/"} creation_date: 2010-09-15T03:39:21Z [Term] id: CL:0002333 name: neural crest derived adipocyte def: "An adipocyte derived from a neural crest cell." [GOC:tfm, PMID:17507398] is_a: CL:0000136 ! adipocyte is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: CL:0000136 ! adipocyte intersection_of: develops_from CL:0000333 ! migratory neural crest cell relationship: develops_from CL:0000005 ! fibroblast neural crest derived property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-20T02:25:25Z [Term] id: CL:0002350 name: endocardial cell def: "An endothelial cell that lines the intracavitary lumen of the heart, separating the circulating blood from the underlying myocardium. This cell type releases a number of vasoactive substances including prostacyclin, nitrous oxide and endothelin." [GOC:tfm, ISSN:0452-3458] subset: cellxgene_subset subset: human_reference_atlas synonym: "endocardial endothelial cell" EXACT [] synonym: "endothelial cell of endocardium" EXACT [FMA:75621] xref: FMA:75621 is_a: CL:0010008 ! cardiac endothelial cell intersection_of: CL:0000115 ! endothelial cell intersection_of: part_of UBERON:0002165 ! endocardium relationship: part_of UBERON:0002165 ! endocardium property_value: RO:0002175 NCBITaxon:9606 property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-21T04:33:05Z [Term] id: CL:0002351 name: progenitor cell of endocrine pancreas def: "A progenitor cell that is able to differentiate into the pancreas alpha, beta and delta endocrine cells. This cell type expresses neurogenin-3 and Isl-1." [GOC:tfm, PMID:20025937, PMID:20217494, PMID:22728667] subset: cellxgene_subset synonym: "pancreatic endocrine progenitor" EXACT [] synonym: "pancreatic islet progenitor cell" EXACT [] is_a: CL:0011026 ! progenitor cell property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-21T04:41:06Z [Term] id: CL:0002352 name: gestational hematopoietic stem cell def: "A hematopoietic stem cell that exists during embryogenesis." [GOC:tfm, ISBN:978-60327-246-6] is_a: CL:0000037 ! hematopoietic stem cell intersection_of: CL:0000037 ! hematopoietic stem cell intersection_of: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0000922 ! embryo property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-22T09:05:13Z [Term] id: CL:0002359 name: placental hematopoietic stem cell def: "A hematopoietic stem cell of the placenta. This cell type is first observed E10.5 This cell type may give rise to fetal liver hematopoietic stem cells." [GOC:tfm, ISBN:978-1-60327-346-6] is_a: CL:0002352 ! gestational hematopoietic stem cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000037 ! hematopoietic stem cell intersection_of: part_of UBERON:0001987 ! placenta relationship: part_of UBERON:0001987 ! placenta property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-22T10:30:02Z [Term] id: CL:0002363 name: keratocyte def: "A keratocyte is a specialized fibroblast residing in the cornea stroma that has a flattened, dendritic morphology; located between the lamellae with a large flattened nucleus, and lengthy processes which communicate with neighboring cells. This corneal layer, representing about 85-90% of corneal thickness, is built up from highly regular collagenous lamellae and extracellular matrix components. Keratocytes play the major role in keeping it transparent, healing its wounds, and synthesizing its components. This cell type secretes collagen I, V, VI, and keratan sulfate." [GOC:tfm, ISBN:9780702029585] subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas synonym: "corneal fibroblast" EXACT [] synonym: "corneal keratocyte" EXACT [] is_a: CL:0000005 ! fibroblast neural crest derived intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0001777 ! substantia propria of cornea relationship: part_of UBERON:0001777 ! substantia propria of cornea property_value: RO:0002175 NCBITaxon:9606 property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-22T01:57:40Z [Term] id: CL:0002368 name: respiratory epithelial cell def: "An endo-epithelial cell of the respiratory tract." [GOC:tfm] subset: cellxgene_subset synonym: "airway epithelial cell" EXACT [] xref: BTO:0004533 is_a: CL:0002076 {is_inferred="true"} ! endo-epithelial cell intersection_of: CL:0002076 ! endo-epithelial cell intersection_of: part_of UBERON:0000065 ! respiratory tract relationship: part_of UBERON:0000065 ! respiratory tract property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-23T04:38:49Z [Term] id: CL:0002372 name: myotube def: "A transversely striated, synctial muscle cell, formed by the fusion of myoblasts." [GOC:dos, GOC:tfm, ISBN:0323052908, PMID:22274696] synonym: "myotubule" EXACT [] synonym: "single cell sarcomere" EXACT [] xref: FBbt:00005812 is_a: CL:0000228 ! multinucleate cell is_a: CL:0000737 ! striated muscle cell intersection_of: CL:0000187 ! muscle cell intersection_of: has_characteristic PATO:0001908 ! multinucleate intersection_of: has_characteristic PATO:0002478 ! transversely striated intersection_of: has_part GO:0030017 ! sarcomere relationship: has_characteristic PATO:0002478 ! transversely striated property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-24T01:13:01Z [Term] id: CL:0002421 name: nucleated reticulocyte def: "A reticulocyte that retains the nucleus and other organelles. Found in birds, fish, amphibians and reptiles." [GOC:tfm, PMID:18182572, PMID:9011180, PMID:9046052] is_a: CL:0000558 {is_inferred="true"} ! reticulocyte is_a: CL:0002242 ! nucleate cell intersection_of: CL:0000558 ! reticulocyte intersection_of: has_characteristic PATO:0002505 ! nucleated property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-10-15T09:24:05Z [Term] id: CL:0002422 name: enucleated reticulocyte def: "A reticulocyte lacking a nucleus and showing a basophilic reticulum under vital staining due to the presence of ribosomes." [GOC:tfm, ISBN:0-12203-052-4, ISBN:0721601464] subset: cellxgene_subset xref: CALOHA:TS-0864 xref: FMA:66785 is_a: CL:0000225 ! anucleate cell is_a: CL:0000558 {is_inferred="true"} ! reticulocyte intersection_of: CL:0000558 ! reticulocyte intersection_of: has_characteristic PATO:0001405 ! anucleate intersection_of: has_part GO:0005840 ! ribosome relationship: has_part GO:0005840 ! ribosome property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-10-15T09:24:08Z [Term] id: CL:0002494 name: cardiocyte def: "A cell located in the heart, including both muscle and non muscle cells." [GOC:tfm] comment: From Onard of the FMA: Cardiac muscle cell or cardiac myocyte is a striated muscle cell. Cardiocyte on the other hand is any cell in the heart which includes cells other than muscle cells (e.g. endothelial cell of endocardium). Unless there is a consensus among anatomists that cardiocytes refer only to muscle cells, we will treat them as a general class of cells in the heart. synonym: "heart cell" EXACT [] xref: BTO:0001539 xref: CALOHA:TS-0115 xref: FMA:83808 xref: FMA:84791 is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: part_of UBERON:0007100 ! primary circulatory organ relationship: part_of UBERON:0007100 ! primary circulatory organ property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-12-07T09:37:22Z [Term] id: CL:0002503 name: adventitial cell def: "A cell of the adventitial layer of ductal structures such as the uterer, defent duct, biliary duct, etc" [GOC:tfm] subset: cellxgene_subset xref: BTO:0002441 xref: FMA:84639 is_a: CL:0000630 ! supporting cell is_a: CL:0002320 ! connective tissue cell intersection_of: CL:0002320 ! connective tissue cell intersection_of: part_of UBERON:0005742 ! adventitia relationship: part_of UBERON:0005742 ! adventitia property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-12-07T04:03:56Z [Term] id: CL:0002504 name: enteric smooth muscle cell def: "A smooth muscle cell of the intestine." [GOC:tfm] subset: cellxgene_subset synonym: "intestinal smooth muscle cell" EXACT [] is_a: CL:0000192 {is_inferred="true"} ! smooth muscle cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0000160 ! intestine relationship: part_of UBERON:0000160 ! intestine property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-01-17T03:39:38Z [Term] id: CL:0002518 name: kidney epithelial cell def: "An epithelial cell of the kidney." [GOC:tfm, KUPO:SJ] subset: cellxgene_subset xref: KUPO:0001019 is_a: CL:0000066 ! epithelial cell is_a: CL:1000497 {is_inferred="true"} ! kidney cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0002113 ! kidney property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-02-08T10:46:34Z [Term] id: CL:0002521 name: subcutaneous adipocyte def: "An adipocyte that is part of subcutaneous adipose tissue." [GOC:tfm] subset: cellxgene_subset subset: human_reference_atlas synonym: "subcutaneous fat cell" EXACT [] is_a: CL:0000136 {is_inferred="true"} ! adipocyte is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000136 ! adipocyte intersection_of: part_of UBERON:0002190 ! subcutaneous adipose tissue relationship: part_of UBERON:0002190 ! subcutaneous adipose tissue property_value: RO:0002175 NCBITaxon:9606 property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-02-21T02:51:22Z [Term] id: CL:0002538 name: intrahepatic cholangiocyte def: "An epithelial cell of the intrahepatic portion of the bile duct. These cells are flattened or cuboidal in shape, and have a small nuclear-to-cytoplasmic ratio relative to large/extrahepatic cholangiocytes." [GOC:tfm, PMID:23720296] subset: cellxgene_subset synonym: "small bile duct cholangiocyte" EXACT [PMID:23720296] is_a: CL:1000488 {is_inferred="true"} ! cholangiocyte intersection_of: CL:1000488 ! cholangiocyte intersection_of: part_of UBERON:0004823 ! intrahepatic bile duct epithelium relationship: part_of UBERON:0004823 ! intrahepatic bile duct epithelium property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-02-28T01:20:20Z [Term] id: CL:0002539 name: aortic smooth muscle cell def: "A smooth muscle cell of the aorta." [GOC:tfm] subset: cellxgene_subset xref: BTO:0004577 is_a: CL:0019018 ! blood vessel smooth muscle cell intersection_of: CL:0000359 ! vascular associated smooth muscle cell intersection_of: part_of UBERON:0004178 ! aorta smooth muscle tissue relationship: part_of UBERON:0004178 ! aorta smooth muscle tissue property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-02-28T01:42:12Z [Term] id: CL:0002540 name: mesenchymal stem cell of the bone marrow def: "A mesenchymal stem cell that is part of the bone marrow." [GOC:tfm] is_a: CL:0000134 ! mesenchymal stem cell is_a: CL:0002092 ! bone marrow cell intersection_of: CL:0000134 ! mesenchymal stem cell intersection_of: part_of UBERON:0002371 ! bone marrow property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-02-28T01:47:47Z [Term] id: CL:0002541 name: chorionic membrane mesenchymal stem cell def: "A mesenchymal stem cell of the chorionic membrane." [GOC:tfm] subset: human_reference_atlas is_a: CL:0000134 ! mesenchymal stem cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000134 ! mesenchymal stem cell intersection_of: part_of UBERON:0003124 ! chorion membrane relationship: part_of UBERON:0003124 ! chorion membrane property_value: RO:0002175 NCBITaxon:9606 property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-02-28T03:04:35Z [Term] id: CL:0002543 name: vein endothelial cell def: "An endothelial cell that is part of the vein." [GOC:tfm] subset: cellxgene_subset subset: human_reference_atlas synonym: "endothelial cell of vein" EXACT [] synonym: "venous endothelial cell" EXACT [] xref: FMA:62104 xref: KUPO:0001099 is_a: CL:0000071 {is_inferred="true"} ! blood vessel endothelial cell intersection_of: CL:0000071 ! blood vessel endothelial cell intersection_of: part_of UBERON:0001638 ! vein relationship: part_of UBERON:0001638 ! vein property_value: RO:0002175 NCBITaxon:9606 property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-02-28T03:48:11Z [Term] id: CL:0002546 name: embryonic blood vessel endothelial progenitor cell def: "An endothelial progenitor cell that participates in angiogenesis during development." [GOC:tfm] comment: See CL:0002619. is_a: CL:0000222 ! mesodermal cell property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-02-28T04:20:39Z [Term] id: CL:0002547 name: fibroblast of the aortic adventitia def: "A fibroblast of the aortic adventitia." [GOC:tfm] is_a: CL:1000306 {is_inferred="true"} ! fibroblast of tunica adventitia of artery intersection_of: CL:1000306 ! fibroblast of tunica adventitia of artery intersection_of: part_of UBERON:0004664 ! aorta tunica adventitia relationship: part_of UBERON:0004664 ! aorta tunica adventitia property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-02-28T04:43:41Z [Term] id: CL:0002548 name: fibroblast of cardiac tissue def: "A fibroblast that is part of the heart." [GOC:tfm] subset: cellxgene_subset synonym: "cardiac fibroblast" EXACT [] is_a: CL:0000057 {is_inferred="true"} ! fibroblast is_a: CL:0002494 {is_inferred="true"} ! cardiocyte is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0000948 ! heart relationship: part_of UBERON:0000948 ! heart property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-02-28T04:57:44Z [Term] id: CL:0002551 name: fibroblast of dermis is_a: CL:0002620 {is_inferred="true"} ! skin fibroblast intersection_of: CL:0002620 ! skin fibroblast intersection_of: part_of UBERON:0002067 ! dermis relationship: part_of UBERON:0002067 ! dermis property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-02-28T05:05:33Z [Term] id: CL:0002553 name: fibroblast of lung def: "A fibroblast that is part of lung." [GOC:tfm] subset: cellxgene_subset xref: BTO:0000764 xref: CALOHA:TS-0575 is_a: CL:0000057 {is_inferred="true"} ! fibroblast is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0002048 ! lung relationship: part_of UBERON:0002048 ! lung property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-02-28T05:11:03Z [Term] id: CL:0002557 name: fibroblast of pulmonary artery def: "A fibroblast of pulmonary artery." [GOC:tfm] subset: human_reference_atlas is_a: CL:0000057 {is_inferred="true"} ! fibroblast is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0002012 ! pulmonary artery relationship: part_of UBERON:0002012 ! pulmonary artery property_value: RO:0002175 NCBITaxon:9606 property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-02-28T05:22:27Z [Term] id: CL:0002563 name: intestinal epithelial cell def: "An epithelial cell of the intestine." [GOC:tfm] subset: cellxgene_subset is_a: CL:0002251 ! epithelial cell of alimentary canal intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0000160 ! intestine relationship: part_of UBERON:0001277 ! intestinal epithelium property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-03-01T05:18:31Z [Term] id: CL:0002569 name: mesenchymal stem cell of umbilical cord def: "A mesenchymal stem cell of the umbilical cord." [GOC:tfm] is_a: CL:0000134 ! mesenchymal stem cell is_a: CL:0000349 ! extraembryonic cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000134 ! mesenchymal stem cell intersection_of: part_of UBERON:0003422 ! mesenchyme of umbilical cord relationship: part_of UBERON:0003422 ! mesenchyme of umbilical cord property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-03-01T09:55:12Z [Term] id: CL:0002570 name: mesenchymal stem cell of adipose tissue def: "A mesenchymal stem cell of adipose tissue." [GOC:tfm] subset: cellxgene_subset synonym: "mesenchymal stem cell of adipose" EXACT [] is_a: CL:0000134 ! mesenchymal stem cell intersection_of: CL:0000134 ! mesenchymal stem cell intersection_of: part_of UBERON:0001013 ! adipose tissue relationship: part_of UBERON:0001013 ! adipose tissue property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-03-01T09:57:17Z [Term] id: CL:0002571 name: hepatic mesenchymal stem cell def: "A mesenchymal stem cell of liver." [GOC:tfm] is_a: CL:0000134 {is_inferred="true"} ! mesenchymal stem cell is_a: CL:0002195 ! hepatic stem cell intersection_of: CL:0000134 ! mesenchymal stem cell intersection_of: part_of UBERON:0002107 ! liver property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-03-01T09:58:51Z [Term] id: CL:0002572 name: vertebral mesenchymal stem cell def: "A mesenchymal stem cell of the vertebrae." [GOC:tfm] is_a: CL:0000134 {is_inferred="true"} ! mesenchymal stem cell is_a: CL:0001035 ! bone cell intersection_of: CL:0000134 ! mesenchymal stem cell intersection_of: part_of UBERON:0002412 ! vertebra relationship: part_of UBERON:0002412 ! vertebra property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-03-01T10:40:27Z [Term] id: CL:0002574 name: stromal cell of pancreas def: "A stromal cell of the pancreas." [GOC:tfm] subset: human_reference_atlas is_a: CL:0000499 {is_inferred="true"} ! stromal cell intersection_of: CL:0000499 ! stromal cell intersection_of: part_of UBERON:0001264 ! pancreas relationship: part_of UBERON:0001264 ! pancreas property_value: RO:0002175 NCBITaxon:9606 property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-03-02T02:40:41Z [Term] id: CL:0002577 name: placental epithelial cell def: "An epithelial cell of the placenta." [GOC:tfm] is_a: CL:0000066 ! epithelial cell is_a: CL:0000349 {is_inferred="true"} ! extraembryonic cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0001987 ! placenta relationship: part_of UBERON:0001987 ! placenta property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-03-02T03:21:30Z [Term] id: CL:0002584 name: renal cortical epithelial cell def: "An epithelial cell of the kidney cortex." [GOC:tfm] xref: KUPO:0001016 is_a: CL:0002518 {is_inferred="true"} ! kidney epithelial cell is_a: CL:0002681 {is_inferred="true"} ! kidney cortical cell intersection_of: CL:0002518 ! kidney epithelial cell intersection_of: part_of UBERON:0001225 ! cortex of kidney [Term] id: CL:0002585 name: retinal blood vessel endothelial cell def: "A blood vessel endothelial cell that is part of the retina." [GOC:tfm] subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas is_a: CL:0000071 {is_inferred="true"} ! blood vessel endothelial cell is_a: CL:0009004 ! retinal cell is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:0000071 ! blood vessel endothelial cell intersection_of: part_of UBERON:0000966 ! retina relationship: part_of UBERON:0000966 ! retina property_value: RO:0002175 NCBITaxon:9606 property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-03-06T03:28:27Z [Term] id: CL:0002589 name: smooth muscle cell of the brachiocephalic vasculature def: "A smooth muscle cell of the bachiocephalic vasculature." [GOC:tfm] is_a: CL:0019018 ! blood vessel smooth muscle cell intersection_of: CL:0000359 ! vascular associated smooth muscle cell intersection_of: part_of UBERON:0001529 ! brachiocephalic artery relationship: part_of UBERON:0001529 ! brachiocephalic artery property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-03-06T05:00:58Z [Term] id: CL:0002590 name: smooth muscle cell of the brain vasculature def: "A vascular associated smooth muscle cell of the brain vasculature." [GOC:tfm] is_a: CL:0000359 {is_inferred="true"} ! vascular associated smooth muscle cell is_a: CL:0002319 ! neural cell is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:0000359 ! vascular associated smooth muscle cell intersection_of: part_of UBERON:0000955 ! brain relationship: part_of UBERON:0000955 ! brain property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-03-06T05:01:20Z [Term] id: CL:0002591 name: smooth muscle cell of the pulmonary artery def: "A smooth muscle of the pulmonary artery." [GOC:tfm] subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0003336 is_a: CL:0019018 ! blood vessel smooth muscle cell intersection_of: CL:0000359 ! vascular associated smooth muscle cell intersection_of: part_of UBERON:0002012 ! pulmonary artery relationship: part_of UBERON:0002012 ! pulmonary artery property_value: RO:0002175 NCBITaxon:9606 property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-03-06T05:01:28Z [Term] id: CL:0002594 name: smooth muscle cell of the umbilical artery def: "A smooth muscle cell of the umbilical artery." [GOC:tfm] is_a: CL:0019018 ! blood vessel smooth muscle cell intersection_of: CL:0000359 ! vascular associated smooth muscle cell intersection_of: part_of UBERON:0001310 ! umbilical artery relationship: part_of UBERON:0001310 ! umbilical artery property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-03-06T05:01:48Z [Term] id: CL:0002595 name: smooth muscle cell of the subclavian artery def: "A smooth muscle cell of the subclavian artery." [GOC:tfm] is_a: CL:0019018 ! blood vessel smooth muscle cell intersection_of: CL:0000359 ! vascular associated smooth muscle cell intersection_of: part_of UBERON:0001533 ! subclavian artery relationship: part_of UBERON:0001533 ! subclavian artery property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-03-06T05:01:52Z [Term] id: CL:0002596 name: smooth muscle cell of the carotid artery def: "Smooth muscle cell of the carotid artery." [GOC:tfm] is_a: CL:0019018 ! blood vessel smooth muscle cell intersection_of: CL:0000359 ! vascular associated smooth muscle cell intersection_of: part_of UBERON:0005396 ! carotid artery segment relationship: part_of UBERON:0005396 ! carotid artery segment property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-03-06T05:01:56Z [Term] id: CL:0002597 name: smooth muscle cell of bladder def: "A smooth muscle cell of the bladder." [GC:tfm] subset: human_reference_atlas xref: KUPO:0001122 is_a: CL:0000192 {is_inferred="true"} ! smooth muscle cell is_a: CL:1001319 ! bladder cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0001255 ! urinary bladder property_value: RO:0002175 NCBITaxon:9606 property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-03-06T05:43:24Z [Term] id: CL:0002599 name: smooth muscle cell of the esophagus def: "A smooth muscle cell of the esophagus." [GOC:tfm] is_a: CL:0000192 {is_inferred="true"} ! smooth muscle cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0001043 ! esophagus relationship: part_of UBERON:0001043 ! esophagus property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-03-06T05:48:17Z [Term] id: CL:0002601 name: uterine smooth muscle cell def: "A smooth muscle cell of the uterus." [GOC:tfm] subset: cellxgene_subset is_a: CL:0000192 {is_inferred="true"} ! smooth muscle cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0000995 ! uterus relationship: part_of UBERON:0000995 ! uterus property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-03-06T05:53:28Z [Term] id: CL:0002610 name: raphe nuclei neuron def: "A neuron of the raphe nuclei." [GOC:tfm] is_a: CL:0000117 {is_inferred="true"} ! CNS neuron (sensu Vertebrata) is_a: CL:2000029 ! central nervous system neuron intersection_of: CL:0000117 ! CNS neuron (sensu Vertebrata) intersection_of: has_soma_location UBERON:0004684 ! raphe nuclei relationship: has_soma_location UBERON:0004684 ! raphe nuclei property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-03-06T07:42:06Z [Term] id: CL:0002612 name: neuron of the ventral spinal cord def: "A neuron of the ventral spinal cord." [GOC:tfm] is_a: CL:0000117 {is_inferred="true"} ! CNS neuron (sensu Vertebrata) is_a: CL:2000029 ! central nervous system neuron intersection_of: CL:0000117 ! CNS neuron (sensu Vertebrata) intersection_of: has_soma_location UBERON:0002257 ! ventral horn of spinal cord relationship: has_soma_location UBERON:0002257 ! ventral horn of spinal cord property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-03-06T07:46:03Z [Term] id: CL:0002620 name: skin fibroblast def: "A fibroblast of skin." [GOC:tfm] subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0001255 xref: CALOHA:TS-0935 is_a: CL:0000057 {is_inferred="true"} ! fibroblast is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0002097 ! skin of body relationship: part_of UBERON:0002097 ! skin of body property_value: RO:0002175 NCBITaxon:9606 property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-03-14T12:31:49Z [Term] id: CL:0002625 name: seminiferous tubule epithelial cell def: "A cell of the seminiferous tubule epithelium." [GOC:tfm] is_a: CL:0000068 ! duct epithelial cell is_a: CL:0000077 {is_inferred="true"} ! mesothelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0001343 ! seminiferous tubule of testis relationship: part_of UBERON:0004813 ! seminiferous tubule epithelium property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-03-15T11:59:23Z [Term] id: CL:0002632 name: epithelial cell of lower respiratory tract subset: cellxgene_subset is_a: CL:0002368 {is_inferred="true"} ! respiratory epithelial cell intersection_of: CL:0002368 ! respiratory epithelial cell intersection_of: part_of UBERON:0001558 ! lower respiratory tract relationship: part_of UBERON:0001558 ! lower respiratory tract property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-06-21T12:29:31Z [Term] id: CL:0002656 name: glandular cell of endometrium def: "A glandular epithelial cell of the endometrium." [GOC:tfm] xref: FMA:86489 is_a: CL:1001591 ! oviduct secretory cell intersection_of: CL:0000150 ! glandular epithelial cell intersection_of: part_of UBERON:0001295 ! endometrium relationship: part_of UBERON:0001295 ! endometrium property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-07-08T03:54:08Z [Term] id: CL:0002657 name: glandular cell of esophagus def: "A glandular epithelial cell of the esophagus." [GOC:tfm] subset: cellxgene_subset xref: FMA:86548 is_a: CL:0000150 {is_inferred="true"} ! glandular epithelial cell is_a: CL:0002252 {is_inferred="true"} ! epithelial cell of esophagus intersection_of: CL:0000150 ! glandular epithelial cell intersection_of: part_of UBERON:0001043 ! esophagus property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-07-08T03:55:57Z [Term] id: CL:0002658 name: glandular cell of the large intestine def: "A glandular epithelial cell of the large intestine." [GOC:tfm] xref: FMA:87194 is_a: CL:0000150 {is_inferred="true"} ! glandular epithelial cell is_a: CL:0002253 ! epithelial cell of large intestine intersection_of: CL:0000150 ! glandular epithelial cell intersection_of: part_of UBERON:0000059 ! large intestine property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-07-08T04:03:01Z [Term] id: CL:0002659 name: glandular cell of stomach def: "A glandular epithelial cell that is part of the stomach." [GOC:tfm] xref: CALOHA:TS-1284 xref: FMA:86554 is_a: CL:0000150 {is_inferred="true"} ! glandular epithelial cell is_a: CL:0002178 ! epithelial cell of stomach intersection_of: CL:0000150 ! glandular epithelial cell intersection_of: part_of UBERON:0000945 ! stomach property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-07-11T01:20:35Z [Term] id: CL:0002663 name: myocardial endocrine cell of atrium def: "A myocardial endocrine cell that is part of the atrium." [GOC:tfm] xref: FMA:83389 is_a: CL:0002074 {is_inferred="true"} ! myocardial endocrine cell intersection_of: CL:0002074 ! myocardial endocrine cell intersection_of: part_of UBERON:0002081 ! cardiac atrium relationship: part_of UBERON:0002081 ! cardiac atrium property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-07-11T02:45:39Z [Term] id: CL:0002664 name: cardioblast def: "A stem cell that can give rise to multiple cell types (i.e. smooth muscle, endothelial) in the developing heart." [GOC:tfm, PMID:19745164] comment: Discrepancy in develops from origins prevents me from making the assertion that cardioblasts give rise to all instances of cardiocytes as we state cardiac muscle cells develop from cardiac myoblast, which in turn develop from muscle stem cell. synonym: "cardiovascular progenitor cell" EXACT [PMID:17519333, PMID:19745164] synonym: "CPC" RELATED OMO:0003000 [PMID:19745164] is_a: CL:0000048 ! multi fate stem cell property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-07-11T03:15:38Z [Term] id: CL:0002672 name: retinal progenitor cell def: "A multi-fate stem cell that can give rise to different retinal cell types including rod and cone cells." [GOC:tfm, PMID:20959166, PMID:21148186] is_a: CL:0000048 ! multi fate stem cell is_a: UBERON:0004121 ! ectoderm-derived structure relationship: develops_from CL:0000133 ! neurectodermal cell property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-08-16T02:38:01Z [Term] id: CL:0002676 name: neural crest derived neuroblast def: "A neuroblast derived from a neural crest cell." [GOC:tfm, PMID:17407019] is_a: CL:0000031 ! neuroblast (sensu Vertebrata) is_a: CL:0011026 ! progenitor cell is_a: UBERON:0010313 ! neural crest-derived structure relationship: develops_from CL:0000333 ! migratory neural crest cell property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-08-22T09:24:15Z [Term] id: CL:0002680 name: PP cell of intestine def: "A PP cell found in intestine." [GOC:tfm, PMID:2420136, PMID:728970] is_a: CL:0000696 {is_inferred="true"} ! PP cell is_a: CL:1001516 ! intestinal enteroendocrine cell intersection_of: CL:0000696 ! PP cell intersection_of: part_of UBERON:0000160 ! intestine property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-09-27T11:59:01Z [Term] id: CL:0002681 name: kidney cortical cell def: "A cell that is part of a cortex of kidney." [] is_a: CL:1000497 ! kidney cell intersection_of: CL:1000497 ! kidney cell intersection_of: part_of UBERON:0001225 ! cortex of kidney relationship: part_of UBERON:0001225 ! cortex of kidney property_value: term:contributor https://orcid.org/0000-0002-0956-8634 creation_date: 2011-10-25T03:49:41Z [Term] id: CL:0005000 name: spinal cord interneuron def: "A CNS interneuron located in the spinal cord." [CL:CVS] comment: Is_a interneuron, part_of UBERON:0002240. is_a: CL:0000402 {is_inferred="true"} ! CNS interneuron intersection_of: CL:0000099 ! interneuron intersection_of: has_soma_location UBERON:0002240 ! spinal cord relationship: has_soma_location UBERON:0002240 ! spinal cord [Term] id: CL:0005009 name: renal principal cell def: "A cuboidal epithelial cell of the kidney which regulates sodium and potassium balance. The activity of sodium and potassium channels on the apical membrane of the cell is regulated by aldosterone and vasopressin. In mammals this cell type is located in the renal collecting duct system." [CL:CVS] subset: cellxgene_subset is_a: CL:0000075 ! columnar/cuboidal epithelial cell is_a: CL:0002518 ! kidney epithelial cell [Term] id: CL:0005024 name: somatomotor neuron def: "A motor neuron that innervates a skeletal muscle. These motor neurons are all excitatory and cholinergic." [ZFIN:CVS] synonym: "somatic motor neuron" EXACT [] is_a: CL:0000100 ! motor neuron is_a: CL:0000108 ! cholinergic neuron intersection_of: CL:0000100 ! motor neuron intersection_of: synapsed_to CL:0008002 ! skeletal muscle fiber relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata) relationship: part_of RO:0002577 ! system relationship: synapsed_to CL:0008002 ! skeletal muscle fiber [Term] id: CL:0005026 name: hepatoblast def: "Multi fate stem cell that gives rise to both hepatocytes and cholangiocytes as descendants. The term often refers to fetal precursors of hepatocytes (differently from 'hepatic stem cell', usually applied to the self-renewing pool of hepatocyte precursors in the adult liver). Hepatoblasts may also be endogenous, as some stem cells found in the liver come from the bone marrow via blood circulation." [GOC:CVS, https://orcid.org/0000-0003-1940-6740, PMID:18356246, PMID:20483998, PMID:26798363] subset: cellxgene_subset is_a: CL:0000048 ! multi fate stem cell property_value: seeAlso "https://github.com/obophenotype/cell-ontology/issues/800" xsd:string [Term] id: CL:0007001 name: skeletogenic cell def: "Cell that has the potential to form a skeletal cell type (e.g. cells in periosteum, cells in marrow) and produce extracellular matrix (often mineralized) and skeletal tissue (often mineralized)." [GO_REF:0000034] comment: Needs logical definition. Should be capable_of skeletal system morphogenesis? or skeletal tissue development? needs to be added to GO. NOTES:a cell type of the early embryo (see also: mesenchymal cells) that will give rise to mineralized connective tissue. Scleroblasts can differentiate into osteoblasts (bone-forming cells), chondroblasts (cartilage-forming cells), odontoblasts (dentin-forming cells), ameloblasts (enamel-forming cells). The mesenchymal cells developing into osteoblasts and chondroblasts are derived from the mesoderm. Those developing into odontoblasts are neural crest cells. Those developing into ameloblasts are derived from the ectoderm. (http://www.copewithcytokines.de/cope.cgi?key=scleroblasts) synonym: "scleroblast" EXACT [GO_REF:0000034] is_a: CL:0000000 ! cell property_value: term:contributor https://orcid.org/0000-0001-9114-8737 creation_date: 2012-06-15T02:51:27Z [Term] id: CL:0007004 name: premigratory neural crest cell def: "Cell that is part of the neural crest region of the neuroepithelium, prior to migration. Note that not all premigratory neural crest cells may become migratory neural crest cells." [UBERONREF:0000002] is_a: CL:0011012 ! neural crest cell is_a: UBERON:0004121 ! ectoderm-derived structure relationship: develops_from CL:0000133 ! neurectodermal cell relationship: part_of UBERON:0002342 ! neural crest property_value: term:contributor https://orcid.org/0000-0001-9114-8737 creation_date: 2012-06-27T08:27:35Z [Term] id: CL:0007009 name: prechondroblast def: "Skeletogenic cell that has the potential to develop into a chondroblast; and arises from neural crest, meseosdermal and notochordal and connective tissue cells." [GO_REF:0000034] is_a: CL:0000055 ! non-terminally differentiated cell property_value: term:contributor https://orcid.org/0000-0001-9114-8737 creation_date: 2012-06-27T10:44:01Z [Term] id: CL:0008000 name: non-striated muscle cell def: "Any muscle cell in which the fibers are not organised into sarcomeres." [GOC:DOS] is_a: CL:0000187 ! muscle cell [Term] id: CL:0008001 name: hematopoietic precursor cell def: "Any hematopoietic cell that is a precursor of some other hematopoietic cell type." [GOC:dos] subset: cellxgene_subset is_a: CL:0000988 ! hematopoietic cell [Term] id: CL:0008002 name: skeletal muscle fiber def: "A transversely striated, synctial cell of skeletal muscle. It is formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." [GOC:tfm, ISBN:0323052908] subset: cellxgene_subset xref: MESH:D018485 is_a: CL:0000188 ! cell of skeletal muscle is_a: CL:0002372 ! myotube intersection_of: CL:0000187 ! muscle cell intersection_of: has_characteristic PATO:0001908 ! multinucleate intersection_of: has_characteristic PATO:0002478 ! transversely striated intersection_of: has_part GO:0030017 ! sarcomere intersection_of: part_of UBERON:0001134 ! skeletal muscle tissue relationship: develops_from CL:0000515 ! skeletal muscle myoblast [Term] id: CL:0008007 name: visceral muscle cell def: "A muscle cell that is part of some visceral muscle." [GOC:dos] xref: FBbt:00005070 is_a: CL:0000187 ! muscle cell intersection_of: CL:0000187 ! muscle cell intersection_of: part_of UBERON:8600004 ! visceral muscle tissue relationship: part_of UBERON:8600004 ! visceral muscle tissue [Term] id: CL:0008008 name: striated visceral muscle cell def: "A visceral muscle cell that is striated. Examples include the visceral muscle cells of arhtropods." [GOC:dos] is_a: CL:0000737 ! striated muscle cell is_a: CL:0008007 ! visceral muscle cell intersection_of: CL:0008007 ! visceral muscle cell intersection_of: has_characteristic PATO:0001410 {all_some="true"} ! striated [Term] id: CL:0008009 name: transversely striated visceral muscle cell def: "A visceral muscle that is transversely striated. Examples include the visceral muscle cells of arthropods." [GOC:dos] is_a: CL:0008008 ! striated visceral muscle cell intersection_of: CL:0008007 ! visceral muscle cell intersection_of: has_characteristic PATO:0002478 {all_some="true"} ! transversely striated relationship: has_characteristic PATO:0002478 ! transversely striated [Term] id: CL:0008017 name: adult skeletal muscle myoblast def: "A skeletal muscle myoblast that is part of a skeletal mucle. These cells are formed following acivation and division of skeletal muscle satellite cells. They form a transient population that is lost when they fuse to form skeletal muscle fibers." [PMID:23303905] comment: The vast majority of these cells develop from skeletal muscle satellite cells, although there are some reports of other origins. synonym: "myogenic precursor cell" BROAD [PMID:23303905] is_a: CL:0000188 ! cell of skeletal muscle is_a: CL:0000515 ! skeletal muscle myoblast intersection_of: CL:0000056 ! myoblast intersection_of: develops_into CL:0008002 ! skeletal muscle fiber intersection_of: part_of UBERON:0001134 ! skeletal muscle tissue [Term] id: CL:0008019 name: mesenchymal cell def: "A non-polarised cell precursor cell that is part of some mesenchyme, is associated with the cell matrix but is not connected to other cells and is capable of migration." [] subset: cellxgene_subset subset: human_reference_atlas synonym: "mesenchyme cell" EXACT [] is_a: CL:0000219 ! motile cell is_a: CL:0000255 ! eukaryotic cell relationship: capable_of GO:0016477 ! cell migration relationship: part_of UBERON:0003104 ! mesenchyme property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0008022 name: endocardial cushion cell def: "A mesenchymal cell of the endocardial cushion. These cells develop via an epithelial to mesenchymal transition when endocardial cells break cell-to-cell contacts and migrate into the cardiac jelly. Cells from this population form the heart septa and valves." [PMID:18816864] is_a: CL:0000569 ! cardiac mesenchymal cell is_a: CL:0002494 ! cardiocyte is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000569 ! cardiac mesenchymal cell intersection_of: part_of UBERON:0002062 ! endocardial cushion relationship: part_of UBERON:0002062 ! endocardial cushion [Term] id: CL:0008024 name: pancreatic endocrine cell def: "An endocrine cell that is part of the pancreas." [GOC:dos] subset: cellxgene_subset subset: human_reference_atlas is_a: CL:0000083 ! epithelial cell of pancreas is_a: CL:0000164 ! enteroendocrine cell intersection_of: CL:0000163 ! endocrine cell intersection_of: part_of UBERON:0001264 ! pancreas property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0008025 name: noradrenergic neuron def: "A neuron that release noradrenaline (noriphinephrine) as a neurotransmitter." [GOC:dos] is_a: CL:0000459 ! noradrenergic cell is_a: CL:4033050 ! catecholaminergic neuron intersection_of: CL:0000540 ! neuron intersection_of: capable_of GO:0061533 ! norepinephrine secretion, neurotransmission relationship: capable_of GO:0061533 ! norepinephrine secretion, neurotransmission [Term] id: CL:0008028 name: visual system neuron is_a: CL:0000540 ! neuron intersection_of: CL:0000540 ! neuron intersection_of: capable_of_part_of GO:0007601 ! visual perception relationship: capable_of_part_of GO:0007601 ! visual perception property_value: term:contributor https://orcid.org/0000-0002-7073-9172 creation_date: 2017-07-09T19:12:36Z [Term] id: CL:0008034 name: mural cell def: "Mural cells are pericytes and the vascular smooth muscle cells (vSMCs) of the microcirculation." [Wiki:Mural_cell&oldid=930603194] subset: added_for_HCA subset: cellxgene_subset subset: human_reference_atlas is_a: CL:4033054 ! perivascular cell property_value: RO:0002175 NCBITaxon:9606 property_value: term:contributor https://orcid.org/0000-0002-7073-9172 creation_date: 2020-02-29T17:33:55Z [Term] id: CL:0008035 name: microcirculation associated smooth muscle cell is_a: CL:0000359 ! vascular associated smooth muscle cell is_a: CL:0008034 ! mural cell intersection_of: CL:0000359 ! vascular associated smooth muscle cell intersection_of: part_of UBERON:0010523 ! microcirculatory vessel relationship: part_of UBERON:0010523 ! microcirculatory vessel property_value: term:contributor https://orcid.org/0000-0002-7073-9172 creation_date: 2020-02-29T17:37:00Z [Term] id: CL:0009000 name: sensory neuron of spinal nerve def: "A sensory neuron of the spinal nerve that senses body position and sends information about how much the muscle is stretched to the spinal cord." [GOC:nv, GOC:pr] synonym: "spinal sensory neuron" EXACT [] is_a: CL:3000004 ! peripheral sensory neuron intersection_of: CL:0000101 ! sensory neuron intersection_of: has_soma_location UBERON:0001780 ! spinal nerve relationship: has_soma_location UBERON:0001780 ! spinal nerve [Term] id: CL:0009001 name: compound eye retinal cell def: "Any cell in the compound eye, a light sensing organ composed of ommatidia." [] xref: GOC:pr xref: PMID:12021768 is_a: CL:0009004 ! retinal cell [Term] id: CL:0009004 name: retinal cell def: "Any cell in the retina, the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates." [GOC:pr] subset: general_cell_types_upper_slim xref: PMID:10702418 is_a: CL:0002319 ! neural cell intersection_of: CL:0002319 ! neural cell intersection_of: part_of UBERON:0005388 ! photoreceptor array relationship: part_of UBERON:0005388 ! photoreceptor array [Term] id: CL:0009006 name: enteroendocrine cell of small intestine def: "An enteroendocrine cell that is located in the small intestine." [http://orcid.org/0000-0003-3440-1876] subset: cellxgene_subset subset: location_grouping synonym: "small intestine enteroendocrine cell" EXACT [] is_a: CL:1001516 ! intestinal enteroendocrine cell is_a: CL:1001598 ! small intestine glandular cell intersection_of: CL:0000164 ! enteroendocrine cell intersection_of: part_of UBERON:0002108 ! small intestine property_value: term:contributor https://orcid.org/0000-0002-2825-0621 [Term] id: CL:0009018 name: lymphocyte of large intestine lamina propria def: "A lymphocyte that resides in the lamina propria of the large intestine." [https://orcid.org/0000-0003-4183-8865] comment: This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you. subset: human_reference_atlas subset: location_grouping synonym: "lamina propria lymphocyte of large intestine" EXACT [] is_a: CL:0000542 ! lymphocyte intersection_of: CL:0000542 ! lymphocyte intersection_of: part_of UBERON:0011189 ! lamina propria of large intestine relationship: part_of UBERON:0011189 ! lamina propria of large intestine property_value: RO:0002175 NCBITaxon:9606 property_value: term:contributor https://orcid.org/0000-0002-2825-0621 [Term] id: CL:0009019 name: nephrogenic zone cell def: "A kidney cortical cell that is part of the nephrogenic zone." [https://orcid.org/0000-0002-3163-0115, PMID:29449449] subset: added_for_HCA synonym: "cortical nephrogenic niche cell" EXACT [] synonym: "cortical nephrogenic zone cell" EXACT [] is_a: CL:0002681 ! kidney cortical cell intersection_of: CL:0002681 ! kidney cortical cell intersection_of: part_of UBERON:0009871 ! nephrogenic zone relationship: part_of UBERON:0009871 ! nephrogenic zone property_value: term:contributor https://orcid.org/0000-0002-2825-0621 [Term] id: CL:0009021 name: stromal cell of lamina propria of large intestine def: "A stromal cell found in the lamina propria of the large intestine." [http://orcid.org/0000-0003-4183-8865] subset: location_grouping is_a: CL:0000499 ! stromal cell intersection_of: CL:0000499 ! stromal cell intersection_of: part_of UBERON:0011189 ! lamina propria of large intestine relationship: part_of UBERON:0011189 ! lamina propria of large intestine property_value: term:contributor https://orcid.org/0000-0002-2825-0621 [Term] id: CL:0009022 name: stromal cell of lamina propria of small intestine def: "A stromal cell found in the lamina propria of the small intestine." [http://orcid.org/0000-0003-4183-8865] subset: cellxgene_subset subset: location_grouping is_a: CL:0000499 ! stromal cell intersection_of: CL:0000499 ! stromal cell intersection_of: part_of UBERON:0001238 ! lamina propria of small intestine relationship: part_of UBERON:0001238 ! lamina propria of small intestine property_value: term:contributor https://orcid.org/0000-0002-2825-0621 [Term] id: CL:0009024 name: mesothelial cell of small intestine def: "A mesothelial cell that is part of the small intestine." [http://orcid.org/0000-0003-4183-8865] subset: location_grouping is_a: CL:0000077 ! mesothelial cell is_a: CL:0002254 ! epithelial cell of small intestine is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure intersection_of: CL:0000077 ! mesothelial cell intersection_of: part_of UBERON:0002108 ! small intestine property_value: term:contributor https://orcid.org/0000-0002-2825-0621 [Term] id: CL:0009025 name: mesothelial cell of colon def: "A mesothelial cell that is part of the colon." [http://orcid.org/0000-0003-3440-1876, http://orcid.org/0000-0003-4183-8865] subset: location_grouping synonym: "mesothelial cell of large intestine" BROAD [] is_a: CL:0000077 ! mesothelial cell is_a: CL:0011108 ! colon epithelial cell is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure intersection_of: CL:0000077 ! mesothelial cell intersection_of: part_of UBERON:0001155 ! colon property_value: term:contributor https://orcid.org/0000-0002-2825-0621 [Term] id: CL:0009040 name: stromal cell of lamina propria of colon def: "A stromal cell found in the lamina propria of the colon." [http://orcid.org/0000-0003-3440-1876] subset: location_grouping synonym: "stromal cell of colon lamina propria" EXACT [] is_a: CL:0009021 ! stromal cell of lamina propria of large intestine intersection_of: CL:0000499 ! stromal cell intersection_of: part_of UBERON:0007177 ! lamina propria of mucosa of colon relationship: part_of UBERON:0007177 ! lamina propria of mucosa of colon property_value: term:contributor https://orcid.org/0000-0002-2825-0621 [Term] id: CL:0009042 name: enteroendocrine cell of colon def: "An enteroendocrine cell that is located in the colon." [http://orcid.org/0000-0003-3440-1876] subset: cellxgene_subset subset: location_grouping synonym: "colon enteroendocrine cell" EXACT [] is_a: CL:1001516 ! intestinal enteroendocrine cell is_a: CL:1001588 ! colon glandular cell intersection_of: CL:0000164 ! enteroendocrine cell intersection_of: part_of UBERON:0001155 ! colon property_value: term:contributor https://orcid.org/0000-0002-2825-0621 [Term] id: CL:0009044 name: lymphocyte of small intestine lamina propria def: "A lymphocyte that resides in the lamina propria of the small intestine. Lamina propria leukocytes and intraepithelial lymphocytes are the effector compartments of the gut mucosal immune system. Lymphocytes circulate through gut associated lymphoid tissues until recruitment by intestinal antigens. They are involved in the gut immune response." [https://orcid.org/0000-0003-4183-8865, PMID:26551552] comment: This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you. subset: location_grouping synonym: "gastrointestinal tract (lamina propria) lymphocyte of small intestine" EXACT [] synonym: "gastrointestinal tract small intestine (lamina propria) leukocyte" BROAD [] synonym: "lamina propria lymphocyte of small intestine" EXACT [] synonym: "small intestine lamina propria leukocyte" BROAD [] synonym: "small intestine lamina propria leukocyte (LPL)" BROAD [] synonym: "small intestine lamina propria lymphocyte" EXACT [] is_a: CL:0000542 ! lymphocyte intersection_of: CL:0000542 ! lymphocyte intersection_of: part_of UBERON:0001238 ! lamina propria of small intestine relationship: part_of UBERON:0001238 ! lamina propria of small intestine property_value: term:contributor https://orcid.org/0000-0002-2825-0621 [Term] id: CL:0009051 name: T cell of anorectum def: "A T cell that is located in the anorectum." [http://orcid.org/0000-0003-3440-1876] comment: This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you. subset: location_grouping is_a: CL:0000084 ! T cell intersection_of: CL:0000084 ! T cell intersection_of: part_of UBERON:8410050 ! anorectum relationship: part_of UBERON:8410050 ! anorectum property_value: term:contributor https://orcid.org/0000-0002-2825-0621 [Term] id: CL:0009052 name: smooth muscle cell of anorectum def: "A smooth muscle cell that is located in the anorectum." [http://orcid.org/0000-0003-3440-1876] subset: location_grouping synonym: "anorectum smooth muscle cell" EXACT [] is_a: CL:1000279 ! smooth muscle cell of large intestine intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:8410050 ! anorectum relationship: part_of UBERON:8410050 ! anorectum property_value: term:contributor https://orcid.org/0000-0002-2825-0621 [Term] id: CL:0009053 name: stromal cell of anorectum lamina propria def: "A stromal cell found in the lamina propria of the anorectum." [http://orcid.org/0000-0003-3440-1876] subset: location_grouping is_a: CL:0009021 ! stromal cell of lamina propria of large intestine intersection_of: CL:0000499 ! stromal cell intersection_of: part_of UBERON:0011189 ! lamina propria of large intestine intersection_of: part_of UBERON:8410050 ! anorectum relationship: part_of UBERON:8410050 ! anorectum property_value: term:contributor https://orcid.org/0000-0002-2825-0621 [Term] id: CL:0009063 name: enteroendocrine cell of anorectum def: "An enteroendocrine cell that is located in the anorectum." [http://orcid.org/0000-0003-3440-1876] subset: location_grouping synonym: "anorectum enteroendocrine cell" EXACT [] is_a: CL:0002658 ! glandular cell of the large intestine is_a: CL:1001516 ! intestinal enteroendocrine cell intersection_of: CL:0000164 ! enteroendocrine cell intersection_of: part_of UBERON:8410050 ! anorectum relationship: part_of UBERON:8410050 ! anorectum property_value: term:contributor https://orcid.org/0000-0002-2825-0621 [Term] id: CL:0009084 name: epithelial cell of endometrial gland def: "An epithelial cell that is part of an endometrial gland." [https://orcid.org/0000-0003-3440-1876, https://orcid.org/0000-0003-4183-8865] subset: human_reference_atlas subset: location_grouping synonym: "endometrial glandular epithelial cell" EXACT [] xref: EFO:0010710 is_a: CL:0000066 ! epithelial cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0002451 ! endometrial gland relationship: part_of UBERON:0002451 ! endometrial gland property_value: RO:0002175 NCBITaxon:9606 property_value: term:contributor https://orcid.org/0000-0002-2825-0621 property_value: term:date "2021-11-30T16:13:30Z" xsd:dateTime [Term] id: CL:0009092 name: endothelial cell of placenta def: "An endothelial cell that is part of a placenta." [https://orcid.org/0000-0003-3440-1876, https://orcid.org/0000-0003-4183-8865] subset: cellxgene_subset subset: location_grouping synonym: "placental endothelial cell" EXACT [] xref: EFO:0010708 is_a: CL:0000115 ! endothelial cell is_a: CL:0002577 ! placental epithelial cell intersection_of: CL:0000115 ! endothelial cell intersection_of: part_of UBERON:0001987 ! placenta property_value: term:contributor https://orcid.org/0000-0002-2825-0621 property_value: term:date "2021-12-13T13:53:01Z" xsd:dateTime [Term] id: CL:0009093 name: smooth muscle cell of placenta def: "A smooth muscle cell that is part of a placenta." [https://orcid.org/0000-0003-3440-1876, https://orcid.org/0000-0003-4183-8865] subset: location_grouping synonym: "placental smooth muscle cell" EXACT [] xref: EFO:0010709 is_a: CL:0000192 ! smooth muscle cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0001987 ! placenta relationship: part_of UBERON:0001987 ! placenta property_value: term:contributor https://orcid.org/0000-0002-2825-0621 property_value: term:date "2021-12-13T13:56:42Z" xsd:dateTime [Term] id: CL:0009094 name: endothelial cell of hepatic portal vein def: "An endothelial cell that is part of a hepatic portal vein." [https://orcid.org/0000-0003-3440-1876, https://orcid.org/0000-0003-4183-8865, PMID:30348985] subset: location_grouping synonym: "portal endothelial cell" BROAD [] xref: EFO:0010704 is_a: CL:0000115 ! endothelial cell intersection_of: CL:0000115 ! endothelial cell intersection_of: part_of UBERON:0001639 ! hepatic portal vein relationship: part_of UBERON:0001639 ! hepatic portal vein property_value: term:contributor https://orcid.org/0000-0002-2825-0621 property_value: term:date "2021-12-13T14:01:05Z" xsd:dateTime [Term] id: CL:0009095 name: endothelial cell of uterus def: "An endothelial cell that is part of a uterus." [https://orcid.org/0000-0003-3440-1876, https://orcid.org/0000-0003-4183-8865] subset: cellxgene_subset subset: location_grouping synonym: "uterine endothelial cell" EXACT [] xref: EFO:0010711 is_a: CL:0000115 ! endothelial cell intersection_of: CL:0000115 ! endothelial cell intersection_of: part_of UBERON:0000995 ! uterus relationship: part_of UBERON:0000995 ! uterus property_value: term:contributor https://orcid.org/0000-0002-2825-0621 property_value: term:date "2021-12-13T14:39:25Z" xsd:dateTime [Term] id: CL:0009097 name: embryonic skeletal muscle fiber def: "A skeletal muscle fiber found in an embryo. In mammalian embryos, skeletal muscle expresses myosin heavy chain-embryonic (MyHC-emb, encoded by the MYH3 gene), which regulates skeletal muscle development." [http://orcid.org/0000-0003-2034-601X, PMID:32094117, PMID:7196501] is_a: CL:0008002 ! skeletal muscle fiber intersection_of: CL:0008002 ! skeletal muscle fiber intersection_of: existence_starts_and_ends_during UBERON:0000068 ! embryo stage relationship: existence_starts_and_ends_during UBERON:0000068 ! embryo stage property_value: term:contributor https://orcid.org/0000-0002-2825-0621 property_value: term:date "2022-02-21T15:39:10Z" xsd:dateTime [Term] id: CL:0009100 name: hepatic portal fibroblast def: "A fibroblast located in the portal triad. Hepatic portal fibroblast are a non-parenchymal cell population located adjacent to bile duct epithelia in liver and are distinct from stellate cells. They differentiate into fibrogenic myofibroblasts during chronic injury states producing high levels of collagen." [https://orcid.org/0000-0001-7655-4833, PMID:20209607, PMID:24814904] subset: human_reference_atlas synonym: "portal fibroblast" BROAD [] is_a: CL:0000057 ! fibroblast is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0001279 ! portal triad relationship: part_of UBERON:0001279 ! portal triad property_value: RO:0002175 NCBITaxon:9606 property_value: term:contributor https://orcid.org/0000-0002-2825-0621 property_value: term:date "2022-03-17T12:00:44Z" xsd:dateTime [Term] id: CL:0010001 name: stromal cell of bone marrow def: "A stromal cell that is part_of a bone marrow." [] synonym: "bone marrow stromal cell" EXACT [] is_a: CL:0000499 ! stromal cell is_a: CL:0002092 ! bone marrow cell intersection_of: CL:0000499 ! stromal cell intersection_of: part_of UBERON:0002371 ! bone marrow property_value: term:contributor https://orcid.org/0000-0002-6601-2165 [Term] id: CL:0010002 name: epithelial cell of umbilical artery def: "An epithelial cell that is part_of a umbilical artery." [] synonym: "umbilical artery epithelial cell" EXACT [] is_a: CL:0000066 ! epithelial cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0001310 ! umbilical artery relationship: part_of UBERON:0001310 ! umbilical artery property_value: term:contributor https://orcid.org/0000-0002-6601-2165 [Term] id: CL:0010004 name: mononuclear cell of bone marrow def: "A mononuclear cell that is part_of a bone marrow." [] synonym: "bone marrow mononuclear cell" EXACT [] is_a: CL:0000842 ! mononuclear cell is_a: CL:1001610 ! bone marrow hematopoietic cell intersection_of: CL:0000842 ! mononuclear cell intersection_of: part_of UBERON:0002371 ! bone marrow property_value: term:contributor https://orcid.org/0000-0002-6601-2165 [Term] id: CL:0010006 name: cardiac blood vessel endothelial cell is_a: CL:0000071 ! blood vessel endothelial cell is_a: CL:0010008 ! cardiac endothelial cell intersection_of: CL:0000071 ! blood vessel endothelial cell intersection_of: part_of UBERON:0000948 ! heart [Term] id: CL:0010007 name: His-Purkinje system cell is_a: CL:0002494 ! cardiocyte is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000000 ! cell intersection_of: part_of UBERON:0004146 ! His-Purkinje system relationship: part_of UBERON:0004146 ! His-Purkinje system [Term] id: CL:0010008 name: cardiac endothelial cell subset: cellxgene_subset subset: human_reference_atlas is_a: CL:0000115 ! endothelial cell is_a: CL:0002494 ! cardiocyte intersection_of: CL:0000115 ! endothelial cell intersection_of: part_of UBERON:0000948 ! heart relationship: part_of UBERON:0000948 ! heart property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0010009 name: camera-type eye photoreceptor cell synonym: "camera type eye photoreceptor cell" EXACT [] is_a: CL:0000287 ! eye photoreceptor cell is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:0000210 ! photoreceptor cell intersection_of: part_of UBERON:0000019 ! camera-type eye relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata) relationship: part_of UBERON:0000019 ! camera-type eye [Term] id: CL:0010017 name: zygote def: "A zygote in a plant or an animal." [] xref: MESH:D015053 is_a: CL:0000000 ! cell relationship: seeAlso https://github.com/obophenotype/cell-ontology/issues/786 [Term] id: CL:0010020 name: cardiac glial cell is_a: CL:0000125 ! glial cell is_a: CL:0002494 ! cardiocyte is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000125 ! glial cell intersection_of: part_of UBERON:0000948 ! heart relationship: part_of UBERON:0000948 ! heart [Term] id: CL:0010021 name: cardiac myoblast xref: MESH:D032386 is_a: CL:0000056 ! myoblast intersection_of: CL:0000056 ! myoblast intersection_of: develops_into CL:0000746 ! cardiac muscle cell relationship: develops_into CL:0000746 ! cardiac muscle cell [Term] id: CL:0010022 name: cardiac neuron def: "A neuron that has its soma in the heart." [PMID:12486170, PMID:29265764] comment: This term is used in 3 GO terms that were created as part of the heart development focus project. subset: cellxgene_subset is_a: CL:0000540 ! neuron intersection_of: CL:0000540 ! neuron intersection_of: has_soma_location UBERON:0000948 ! heart relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata) relationship: has_soma_location UBERON:0000948 ! heart property_value: seeAlso "https://github.com/obophenotype/cell-ontology/pull/1488" xsd:string [Term] id: CL:0011001 name: spinal cord motor neuron def: "A motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement." [GOC:nv] is_a: CL:0000100 {is_inferred="true"} ! motor neuron is_a: CL:2000029 ! central nervous system neuron intersection_of: CL:0000100 ! motor neuron intersection_of: has_soma_location UBERON:0002240 ! spinal cord relationship: has_soma_location UBERON:0002240 ! spinal cord [Term] id: CL:0011007 name: paraxial cell def: "A cell in the area of mesoderm in the neurulating embryo that flanks and forms simultaneously with the neural tube. The cells of this region give rise to somites." [GOC:NV, PMID:11687492] synonym: "paraxial mesoderm cell" EXACT [] synonym: "presomitic mesoderm cell" NARROW [] synonym: "somitic mesoderm cell" EXACT [] is_a: CL:0000222 ! mesodermal cell intersection_of: CL:0000222 ! mesodermal cell intersection_of: part_of UBERON:0003059 ! presomitic mesoderm relationship: part_of UBERON:0003059 ! presomitic mesoderm [Term] id: CL:0011012 name: neural crest cell def: "A cell of the neural crest. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesynchymal transition and delamination to form migratory neural crest cells." [https://orcid.org/0000-0001-5208-3432, https://orcid.org/0000-0002-9900-7880] subset: cellxgene_subset is_a: CL:0000048 ! multi fate stem cell is_a: CL:0002321 ! embryonic cell (metazoa) [Term] id: CL:0011013 name: motile sperm cell def: "A sperm cell that is cabaple of motion (motility)." [PMID:30612620] is_a: CL:0000019 ! sperm is_a: CL:0000219 ! motile cell intersection_of: CL:0000019 ! sperm intersection_of: capable_of GO:0097722 ! sperm motility relationship: capable_of GO:0097722 ! sperm motility property_value: term:contributor https://orcid.org/0000-0001-5208-3432 [Term] id: CL:0011016 name: flagellated sperm cell def: "A motile sperm cell that contains a slender threadlike microscopic appendage that enables motion." [https://www.lexico.com/en/definition/flagellum, PMID:30612620] is_a: CL:0011013 ! motile sperm cell intersection_of: CL:0011013 ! motile sperm cell intersection_of: capable_of GO:0030317 ! flagellated sperm motility relationship: capable_of GO:0030317 ! flagellated sperm motility property_value: term:contributor https://orcid.org/0000-0001-5208-3432 [Term] id: CL:0011019 name: mesothelial cell of epicardium def: "A mesothelial cell that is part of the epicardium." [] subset: cellxgene_subset is_a: CL:0000077 ! mesothelial cell is_a: CL:0002494 ! cardiocyte intersection_of: CL:0000077 ! mesothelial cell intersection_of: part_of UBERON:0002348 ! epicardium relationship: part_of UBERON:0002348 ! epicardium property_value: term:contributor https://orcid.org/0000-0001-5208-3432 [Term] id: CL:0011021 name: fibroblast of upper back skin def: "A fibroblast that is part of upper back skin." [] is_a: CL:0011022 ! fibroblast of skin of back intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0009015 ! upper back skin relationship: part_of UBERON:0009015 ! upper back skin property_value: term:contributor https://orcid.org/0000-0001-5208-3432 [Term] id: CL:0011022 name: fibroblast of skin of back def: "A fibroblast that is part of skin of back." [] is_a: CL:0002620 ! skin fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0001068 ! skin of back relationship: part_of UBERON:0001068 ! skin of back property_value: term:contributor https://orcid.org/0000-0001-5208-3432 [Term] id: CL:0011026 name: progenitor cell def: "A precursor cell that has a tendency to differentiate into a specific type of cell. They are descendants of stem cells, only they are more constrained in their differentiation potential or capacity for self-renewal, and are often more limited in both senses." [https://doi.org/10.1016/B978-0-12-409503-8.00002-0, ISBN:978-1-62808-994-3] subset: cellxgene_subset is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011115 ! precursor cell intersection_of: CL:0011115 ! precursor cell intersection_of: develops_from CL:0000034 ! stem cell relationship: develops_from CL:0000034 ! stem cell property_value: term:contributor https://orcid.org/0000-0001-5208-3432 [Term] id: CL:0011027 name: skeletal muscle fibroblast def: "Any fibroblast that is part of skeletal muscle tissue." [https://orcid.org/0000-0001-6164-0667, PMID:28369879] subset: cellxgene_subset synonym: "skeleton muscle fibroblast" EXACT [] is_a: CL:0000188 ! cell of skeletal muscle is_a: CL:1001609 ! muscle fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0001134 ! skeletal muscle tissue property_value: term:contributor https://orcid.org/0000-0001-5208-3432 [Term] id: CL:0011030 name: dermal microvascular endothelial cell def: "Any microvascular endothelial cell that is part of the dermis." [BTO:0004574, CL:patterns/cellPartOfAnatomicalEntity] synonym: "dermal microvascular endothelium cell" EXACT [] synonym: "DMEC cell" EXACT [] is_a: CL:2000008 ! microvascular endothelial cell is_a: CL:2000010 ! dermis blood vessel endothelial cell intersection_of: CL:2000008 ! microvascular endothelial cell intersection_of: part_of UBERON:0002067 ! dermis property_value: term:contributor https://orcid.org/0000-0001-5208-3432 [Term] id: CL:0011101 name: chorionic trophoblast cell def: "Cells of the uterine chorion that acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer." [GOC:NV] subset: cellxgene_subset is_a: CL:0000351 ! trophoblast cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000351 ! trophoblast cell intersection_of: part_of UBERON:0003124 ! chorion membrane relationship: part_of UBERON:0003124 ! chorion membrane [Term] id: CL:0011108 name: colon epithelial cell def: "Epithelial cell that is part of the colon epithelium." [GOC:NV] subset: cellxgene_subset synonym: "colonic epithelial cell" EXACT [] is_a: CL:0002253 ! epithelial cell of large intestine intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0001155 ! colon relationship: part_of UBERON:0000397 ! colonic epithelium [Term] id: CL:0011115 name: precursor cell def: "A cell that, by division or terminal differentiation, can give rise to other cell types." [GOC:dos] comment: Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell. subset: cellxgene_subset is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: capable_of GO:0030154 ! cell differentiation relationship: capable_of GO:0030154 ! cell differentiation [Term] id: CL:0017500 name: neutrophillic cytoplasm def: "Cytoplasm that exhibits a characteristic staining and color, pale-pink, with Wright-Giemsa stain." [GOC:add] is_a: GO:0005737 ! cytoplasm intersection_of: GO:0005737 ! cytoplasm intersection_of: has_characteristic PATO:0070046 ! neutrophillic relationship: has_characteristic PATO:0070046 ! neutrophillic property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-05-25T01:36:34Z [Term] id: CL:0017502 name: acidophilic cytoplasm def: "Cytoplasm that exhibits a characteristic staining and color, red or pink, with Eosin stain." [GOC:add] synonym: "eosinophilic" NARROW [] is_a: GO:0005737 ! cytoplasm intersection_of: GO:0005737 ! cytoplasm intersection_of: has_characteristic PATO:0002418 ! acidophilic relationship: has_characteristic PATO:0002418 ! acidophilic property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2009-12-22T04:23:25Z [Term] id: CL:0017503 name: basophilic cytoplasm def: "Cytoplasm that exhibits molecular interaction for basic dyes under specific pH conditions." [GOC:tfm] is_a: GO:0005737 ! cytoplasm intersection_of: GO:0005737 ! cytoplasm intersection_of: has_characteristic PATO:0002094 ! basophilic relationship: has_characteristic PATO:0002094 ! basophilic property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2009-12-22T04:24:54Z [Term] id: CL:0017504 name: polychromatophilic cytoplasm def: "Cytoplasm that exhibits affinity for both basic and acid stains under specific pH conditions." [GOC:tfm] is_a: GO:0005737 ! cytoplasm intersection_of: GO:0005737 ! cytoplasm intersection_of: has_characteristic PATO:0070047 ! polychromatophilic relationship: has_characteristic PATO:0070047 ! polychromatophilic property_value: term:contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2009-12-28T04:25:23Z [Term] id: CL:0019018 name: blood vessel smooth muscle cell def: "A smooth muscle cell that is part of any blood vessel." [PMID:9108778] subset: human_reference_atlas synonym: "smooth muscle cell of blood vessel" EXACT [] is_a: CL:0000359 ! vascular associated smooth muscle cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0001981 ! blood vessel relationship: part_of UBERON:0001981 ! blood vessel property_value: RO:0002175 NCBITaxon:9606 property_value: term:contributor https://orcid.org/0000-0003-2034-601X property_value: term:date "2020-07-21T12:42:48Z" xsd:dateTime [Term] id: CL:0019020 name: extrahepatic cholangiocyte def: "An epithelial cell of the extrahepatic bile ducts, including the left and right hepatic duct, common hepatic duct, and common bile duct. They are columnar in shape, and have a large nuclear-to-cytoplasmic ratio relative to small/intrahepatic cholangiocytes." [PMID:23720296] synonym: "large bile duct cholangiocyte" EXACT [PMID:23720296] is_a: CL:1000488 ! cholangiocyte intersection_of: CL:1000488 ! cholangiocyte intersection_of: part_of UBERON:0004822 ! extrahepatic bile duct epithelium relationship: part_of UBERON:0004822 ! extrahepatic bile duct epithelium property_value: term:contributor https://orcid.org/0000-0003-2034-601X property_value: term:date "2020-09-03T12:24:24Z" xsd:dateTime [Term] id: CL:0019021 name: endothelial cell of periportal hepatic sinusoid def: "An endothelial cell found in the periportal region hepatic sinusoid, near the portal triad. The fenestrae of these cells are larger but fewer in number compared with those of endothelial cells near the centrilobular region of the hepatic sinusoid." [PMID:27423426] subset: cellxgene_subset synonym: "periportal hepatic sinusoidal endothelial cell" EXACT [PMID:30348985] synonym: "periportal LSEC" EXACT [PMID:28287163] xref: EFO:0010705 is_a: CL:1000398 ! endothelial cell of hepatic sinusoid intersection_of: CL:1000398 ! endothelial cell of hepatic sinusoid intersection_of: adjacent_to UBERON:0001279 ! portal triad relationship: adjacent_to UBERON:0001279 ! portal triad property_value: term:contributor https://orcid.org/0000-0003-2034-601X property_value: term:date "2020-09-09T13:56:47Z" xsd:dateTime [Term] id: CL:0019022 name: endothelial cell of pericentral hepatic sinusoid def: "An endothelial cell found in the centrilobular region hepatic sinusoid, near the central vein. The fenestrae of these cells are smaller but more numerous compared with those of endothelial cells near the periportal region of the hepatic sinusoid." [PMID:27423426] subset: cellxgene_subset synonym: "central venous hepatic sinusoidal endothelial cell" EXACT [PMID:30348985] synonym: "pericentral LSEC" EXACT [PMID:28287163] xref: EFO:0010706 is_a: CL:1000398 ! endothelial cell of hepatic sinusoid intersection_of: CL:1000398 ! endothelial cell of hepatic sinusoid intersection_of: adjacent_to UBERON:0006841 ! central vein of liver relationship: adjacent_to UBERON:0006841 ! central vein of liver property_value: term:contributor https://orcid.org/0000-0003-2034-601X property_value: term:date "2020-09-10T12:38:29Z" xsd:dateTime [Term] id: CL:1000090 name: pronephric nephron tubule epithelial cell is_a: CL:1000449 ! epithelial cell of nephron is_a: CL:1000507 ! kidney tubule cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0005310 ! pronephric nephron tubule relationship: part_of UBERON:0005310 ! pronephric nephron tubule [Term] id: CL:1000123 name: metanephric nephron tubule epithelial cell is_a: CL:1000449 ! epithelial cell of nephron is_a: CL:1000507 ! kidney tubule cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0005146 ! metanephric nephron tubule relationship: part_of UBERON:0005146 ! metanephric nephron tubule [Term] id: CL:1000222 name: stomach neuroendocrine cell is_a: CL:0000164 ! enteroendocrine cell is_a: CL:0000165 ! neuroendocrine cell is_a: CL:0002659 ! glandular cell of stomach intersection_of: CL:0000165 ! neuroendocrine cell intersection_of: part_of UBERON:0000945 ! stomach relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata) [Term] id: CL:1000223 name: lung neuroendocrine cell def: "A neuroendocrine cell that is part of respiratory epithelium of the lung and is involved in the sensory detection of environmental stimuli, including hypoxia, nicotine and air pressure. Ultrastructurally, this cell type is characterized by the presence of cytoplasmic dense core granules, which are considered the storage sites of amine and peptide hormones. Lung neuroendocrine cells are innervated and appear as solitary cells or as clustered masses, localized at airway bifurcation sites, called neuroepithelial bodies that can release serotonin in response to hypoxia and interact with sensory nerve terminals. Lung neuroendocrine cells also function as reserve stem cells that repair the surrounding epithelium after injury." [doi:10.3109/01902148209069653, doi:10.7554/eLife.78216, PMID:33355253] subset: cellxgene_subset subset: human_reference_atlas synonym: "PNEC" RELATED OMO:0003000 [PMID:33355253] synonym: "pulmonary neuroendocrine cell" EXACT [PMID:33355253] is_a: CL:0000006 ! neuronal receptor cell is_a: CL:0000082 ! epithelial cell of lung is_a: CL:0000098 ! sensory epithelial cell is_a: CL:0000165 ! neuroendocrine cell is_a: CL:0000206 ! chemoreceptor cell is_a: CL:0000458 ! serotonin secreting cell is_a: CL:1000272 ! lung secretory cell intersection_of: CL:0000165 ! neuroendocrine cell intersection_of: part_of UBERON:0002048 ! lung relationship: capable_of GO:0070483 ! detection of hypoxia relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata) relationship: has_part GO:0031045 ! dense core granule property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1000271 name: lung ciliated cell subset: cellxgene_subset subset: human_reference_atlas is_a: CL:4030034 ! respiratory ciliated cell intersection_of: CL:0000064 ! ciliated cell intersection_of: part_of UBERON:0002048 ! lung relationship: part_of UBERON:0002048 ! lung property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1000272 name: lung secretory cell subset: cellxgene_subset is_a: CL:0000151 ! secretory cell is_a: CL:0000255 ! eukaryotic cell is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: CL:0000151 ! secretory cell intersection_of: part_of UBERON:0002048 ! lung relationship: part_of UBERON:0002048 ! lung [Term] id: CL:1000274 name: trophectodermal cell synonym: "trophectoderm cell" EXACT [] is_a: CL:0000349 ! extraembryonic cell [Term] id: CL:1000275 name: smooth muscle cell of small intestine def: "A smooth muscle cell that is part of the small intestine." [GOC:tfm] subset: cellxgene_subset synonym: "non-striated muscle fiber of small intestine" EXACT [FMA:15050] xref: FMA:15050 is_a: CL:0002504 {is_inferred="true"} ! enteric smooth muscle cell intersection_of: CL:0002504 ! enteric smooth muscle cell intersection_of: part_of UBERON:0002108 ! small intestine relationship: part_of UBERON:0002108 ! small intestine [Term] id: CL:1000276 name: smooth muscle fiber of duodenum def: "A smooth muscle cell that is part of the duodenum." [GOC:tfm] synonym: "non-striated muscle fiber of duodenum" EXACT [FMA:15058] xref: FMA:15058 is_a: CL:1000275 {is_inferred="true"} ! smooth muscle cell of small intestine intersection_of: CL:1000275 ! smooth muscle cell of small intestine intersection_of: part_of UBERON:0002114 ! duodenum relationship: part_of UBERON:0002114 ! duodenum [Term] id: CL:1000279 name: smooth muscle cell of large intestine def: "A smooth muscle cell that is part of the large intestine." [GOC:tfm] subset: cellxgene_subset subset: human_reference_atlas synonym: "non-striated muscle fiber of large intestine" EXACT [FMA:15653] xref: FMA:15653 is_a: CL:0002504 {is_inferred="true"} ! enteric smooth muscle cell intersection_of: CL:0002504 ! enteric smooth muscle cell intersection_of: part_of UBERON:0000059 ! large intestine relationship: part_of UBERON:0000059 ! large intestine property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1000280 name: smooth muscle cell of colon def: "A smooth muscle cell that is part of the colon." [GOC:tfm] synonym: "non-striated muscle fiber of colon" EXACT [FMA:15663] xref: FMA:15663 is_a: CL:1000279 ! smooth muscle cell of large intestine intersection_of: CL:0002504 ! enteric smooth muscle cell intersection_of: part_of UBERON:0001155 ! colon relationship: part_of UBERON:0001155 ! colon [Term] id: CL:1000285 name: smooth muscle cell of sigmoid colon def: "A smooth muscle cell that is part of the sigmoid colon." [GOC:tfm] synonym: "non-striated muscle fiber of sigmoid colon" EXACT [FMA:17521] xref: FMA:17521 is_a: CL:1000280 {is_inferred="true"} ! smooth muscle cell of colon intersection_of: CL:1000280 ! smooth muscle cell of colon intersection_of: part_of UBERON:0001159 ! sigmoid colon relationship: part_of UBERON:0001159 ! sigmoid colon [Term] id: CL:1000286 name: smooth muscle cell of rectum def: "A smooth muscle cell that is part of the rectum." [GOC:tfm] synonym: "non-striated muscle fiber of rectum" EXACT [FMA:17522] synonym: "smooth muscle fiber of rectum" EXACT [] xref: FMA:17522 is_a: CL:1000279 ! smooth muscle cell of large intestine intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0001052 ! rectum relationship: part_of UBERON:0001052 ! rectum [Term] id: CL:1000296 name: epithelial cell of urethra def: "An epithelial cell that is part of the urethra." [GOC:tfm] subset: cellxgene_subset xref: FMA:256165 is_a: CL:0000066 ! epithelial cell is_a: CL:1001320 ! urethra cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0000057 ! urethra [Term] id: CL:1000303 name: fibroblast of areolar connective tissue def: "A fibroblast that is part of the areolar connective tissue." [GOC:tfm] xref: FMA:261279 is_a: CL:0000057 {is_inferred="true"} ! fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0006815 ! areolar connective tissue relationship: part_of UBERON:0006815 ! areolar connective tissue [Term] id: CL:1000306 name: fibroblast of tunica adventitia of artery def: "A fibroblast that is part of the tunica adventitia of artery." [GOC:tfm] xref: FMA:261285 is_a: CL:0000057 {is_inferred="true"} ! fibroblast is_a: CL:0002503 ! adventitial cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0005734 ! tunica adventitia of blood vessel relationship: part_of UBERON:0005734 ! tunica adventitia of blood vessel [Term] id: CL:1000307 name: fibroblast of dense regular elastic tissue def: "A fibroblast that is part of the dense regular elastic tissue." [GOC:tfm] xref: FMA:261287 is_a: CL:0000057 ! fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0007846 ! dense regular connective tissue relationship: part_of UBERON:0002521 ! elastic tissue relationship: part_of UBERON:0007846 ! dense regular connective tissue [Term] id: CL:1000309 name: epicardial adipocyte def: "An adipocyte that is part of the epicardial fat." [GOC:tfm] subset: cellxgene_subset subset: human_reference_atlas synonym: "adipocyte of epicardial fat" EXACT [FMA:261293] synonym: "epicardial fat cell" EXACT [FMA:261293] xref: FMA:261293 is_a: CL:0000136 ! adipocyte is_a: CL:0002494 ! cardiocyte is_a: UBERON:0004120 ! mesoderm-derived structure relationship: part_of UBERON:0002348 ! epicardium property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1000310 name: adipocyte of epicardial fat of right ventricle def: "An adipocyte that is part of the epicardial fat of right ventricle." [GOC:tfm] synonym: "epicardial adipocyte of right ventricle" EXACT [FMA:261297] synonym: "epicardial fat cell of right ventricle" EXACT [FMA:261297] xref: FMA:261297 is_a: CL:1000309 ! epicardial adipocyte intersection_of: CL:1000309 ! epicardial adipocyte intersection_of: part_of UBERON:0002080 ! heart right ventricle relationship: part_of UBERON:0002080 ! heart right ventricle [Term] id: CL:1000311 name: adipocyte of epicardial fat of left ventricle def: "An adipocyte that is part of the epicardial fat of left ventricle." [GOC:tfm] subset: cellxgene_subset synonym: "epicardial adipocyte of left ventricle" EXACT [FMA:261300] synonym: "epicardial fat cell of left ventricle" EXACT [FMA:261300] xref: FMA:261300 is_a: CL:1000309 ! epicardial adipocyte intersection_of: CL:1000309 ! epicardial adipocyte intersection_of: part_of UBERON:0002084 ! heart left ventricle relationship: part_of UBERON:0002084 ! heart left ventricle [Term] id: CL:1000361 name: transitional myocyte of interatrial septum def: "A transitional myocyte that is part of the interatrial septum." [GOC:tfm] xref: FMA:263152 is_a: CL:0002073 {is_inferred="true"} ! transitional myocyte is_a: CL:2000022 ! cardiac septum cell intersection_of: CL:0002073 ! transitional myocyte intersection_of: part_of UBERON:0002085 ! interatrial septum relationship: part_of UBERON:0002085 ! interatrial septum [Term] id: CL:1000362 name: transitional myocyte of interventricular septum def: "A transitional myocyte that is part of the interventricular septum." [GOC:tfm] xref: FMA:263154 is_a: CL:0002073 {is_inferred="true"} ! transitional myocyte is_a: CL:2000022 ! cardiac septum cell intersection_of: CL:0002073 ! transitional myocyte intersection_of: part_of UBERON:0002094 ! interventricular septum relationship: part_of UBERON:0002094 ! interventricular septum [Term] id: CL:1000376 name: Purkinje myocyte of interventricular septum def: "A Purkinje myocyte that is part of the interventricular septum." [GOC:tfm] xref: FMA:263182 is_a: CL:0002068 {is_inferred="true"} ! Purkinje myocyte is_a: CL:2000022 ! cardiac septum cell intersection_of: CL:0002068 ! Purkinje myocyte intersection_of: part_of UBERON:0002094 ! interventricular septum relationship: part_of UBERON:0002094 ! interventricular septum [Term] id: CL:1000398 name: endothelial cell of hepatic sinusoid def: "An endothelial cell that is part of the hepatic sinusoid. These cells possess flattened areas containing perforations about 0.1 micrometers in diameter, known as fenestrae. The fenestrae are arranged in groups known as sieve plates." [GOC:tfm, PMID:3926620] subset: cellxgene_subset subset: human_reference_atlas synonym: "endotheliocyte of hepatic sinusoid" EXACT [FMA:62911] synonym: "liver sinusoidal endothelial cell" EXACT [PMID:30348985] synonym: "LSEC" EXACT [PMID:30348985] xref: BTO:000125 xref: FMA:62911 is_a: CL:0002262 ! endothelial cell of sinusoid is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure intersection_of: CL:0000115 ! endothelial cell intersection_of: part_of UBERON:0001281 ! hepatic sinusoid relationship: part_of UBERON:0001281 ! hepatic sinusoid property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1000409 name: myocyte of sinoatrial node def: "A muscle cell that is part of the sinoatrial node." [FMA:67102, GOC:tfm] synonym: "SA nodal myocyte" EXACT [FMA:67102] synonym: "SA node cardiac muscle cell" EXACT [GOC:pr] synonym: "sinoatrial node cell" EXACT [GOC:pr] synonym: "sinoatrial node myocyte" EXACT [] synonym: "sinuatrial node myocyte" EXACT [FMA:67102] xref: FMA:67102 is_a: CL:0002072 ! nodal myocyte is_a: CL:0008009 ! transversely striated visceral muscle cell intersection_of: CL:0000187 ! muscle cell intersection_of: part_of UBERON:0002351 ! sinoatrial node relationship: part_of UBERON:0002351 ! sinoatrial node [Term] id: CL:1000410 name: myocyte of atrioventricular node def: "A muscle cell that is part of the atrioventricular node." [FMA:67106, GOC:tfm] synonym: "atrioventricular node cell" EXACT [GOC:pr] synonym: "atrioventricular node myocyte" EXACT [FMA:67106] synonym: "AV nodal myocyte" EXACT [FMA:67106] synonym: "AV node cardiac muscle cell" EXACT [GOC:pr] synonym: "AV node cell" EXACT [GOC:pr] xref: FMA:67106 is_a: CL:0002072 ! nodal myocyte is_a: CL:0008009 ! transversely striated visceral muscle cell is_a: CL:2000022 ! cardiac septum cell intersection_of: CL:0000187 ! muscle cell intersection_of: part_of UBERON:0002352 ! atrioventricular node relationship: part_of UBERON:0002352 ! atrioventricular node [Term] id: CL:1000412 name: endothelial cell of arteriole def: "An endothelial cell that is part of the arteriole." [GOC:tfm] subset: human_reference_atlas xref: FMA:67760 xref: KUPO:0001097 is_a: CL:0000071 {is_inferred="true"} ! blood vessel endothelial cell intersection_of: CL:0000115 ! endothelial cell intersection_of: part_of UBERON:0001980 ! arteriole relationship: part_of UBERON:0001980 ! arteriole property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1000413 name: endothelial cell of artery def: "A blood vessel endothelial cell that is part of an arterial endothelium." [GOC:tfm] subset: cellxgene_subset subset: human_reference_atlas synonym: "arterial endothelial cell" EXACT [] xref: BTO:0004758 xref: FMA:67761 xref: KUPO:0001095 is_a: CL:0000071 ! blood vessel endothelial cell intersection_of: CL:0000115 ! endothelial cell intersection_of: part_of UBERON:0001637 ! artery relationship: part_of UBERON:0001917 ! endothelium of artery property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1000414 name: endothelial cell of venule def: "An endothelial cell that is part of the venule." [GOC:tfm] subset: cellxgene_subset subset: human_reference_atlas xref: FMA:67762 is_a: CL:0002139 {is_inferred="true"} ! endothelial cell of vascular tree intersection_of: CL:0002139 ! endothelial cell of vascular tree intersection_of: part_of UBERON:0001979 ! venule relationship: part_of UBERON:0001979 ! venule property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1000415 name: epithelial cell of gallbladder def: "An epithelial cell that is part of the gallbladder." [GOC:tfm] xref: FMA:67780 is_a: CL:0000066 ! epithelial cell is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0002110 ! gallbladder relationship: part_of UBERON:0002110 ! gallbladder [Term] id: CL:1000428 name: stem cell of epidermis def: "A somatic stem cell that is part of the epidermis." [GOC:tfm] subset: cellxgene_subset synonym: "epidermal stem cell" EXACT [FMA:70541] xref: FMA:70541 is_a: CL:0000723 {is_inferred="true"} ! somatic stem cell is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:0000723 ! somatic stem cell intersection_of: part_of UBERON:0001003 ! skin epidermis relationship: part_of UBERON:0001003 ! skin epidermis [Term] id: CL:1000443 name: ciliary muscle cell def: "A smooth muscle cell that is part of the ciliary body." [GOC:tfm] subset: cellxgene_subset subset: eye_upper_slim synonym: "smooth muscle cell of ciliary body" EXACT [FMA:70610] xref: FMA:70610 is_a: CL:0000192 {is_inferred="true"} ! smooth muscle cell is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0001775 ! ciliary body relationship: part_of UBERON:0001775 ! ciliary body [Term] id: CL:1000444 name: mesothelial cell of anterior chamber of eye def: "A mesothelial cell that is part of the anterior chamber of eyeball." [GOC:tfm] xref: FMA:70615 is_a: CL:0000077 ! mesothelial cell is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:0000077 ! mesothelial cell intersection_of: part_of UBERON:0001766 ! anterior chamber of eyeball relationship: part_of UBERON:0001766 ! anterior chamber of eyeball [Term] id: CL:1000449 name: epithelial cell of nephron def: "An epithelial cell that is part of the nephron." [GOC:tfm] subset: cellxgene_subset xref: FMA:70965 is_a: CL:0002518 ! kidney epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0001285 ! nephron relationship: part_of UBERON:0001285 ! nephron [Term] id: CL:1000454 name: kidney collecting duct epithelial cell def: "An epithelial cell that is part of the collecting duct of renal tubule." [GOC:tfm] subset: cellxgene_subset subset: human_reference_atlas subset: kidney_upper_slim synonym: "epithelial cell of renal collecting tubule" EXACT [FMA:70982] xref: FMA:70982 xref: KUPO:0001059 is_a: CL:0000072 {is_inferred="true"} ! non-branched duct epithelial cell is_a: CL:1000449 ! epithelial cell of nephron is_a: CL:1001225 {is_inferred="true"} ! kidney collecting duct cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0001232 ! collecting duct of renal tubule property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1000456 name: mesothelial cell of parietal peritoneum def: "A mesothelial cell that is part of the parietal peritoneum." [GOC:tfm] xref: FMA:72142 is_a: CL:1000490 ! mesothelial cell of peritoneum intersection_of: CL:0000077 ! mesothelial cell intersection_of: part_of UBERON:0001366 ! parietal peritoneum relationship: part_of UBERON:0001366 ! parietal peritoneum [Term] id: CL:1000457 name: mesothelial cell of visceral peritoneum def: "A mesothelial cell that is part of the visceral peritoneum." [GOC:tfm] subset: human_reference_atlas xref: FMA:72143 is_a: CL:1000490 ! mesothelial cell of peritoneum intersection_of: CL:0000077 ! mesothelial cell intersection_of: part_of UBERON:0001178 ! visceral peritoneum relationship: part_of UBERON:0001178 ! visceral peritoneum property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1000478 name: transitional myocyte of sinoatrial node def: "A transitional myocyte that is part of the sinoatrial node." [GOC:tfm] synonym: "transitinal myocyte of sinuatrial node" EXACT [] xref: FMA:83384 is_a: CL:0002073 {is_inferred="true"} ! transitional myocyte is_a: CL:1000409 ! myocyte of sinoatrial node intersection_of: CL:0002073 ! transitional myocyte intersection_of: part_of UBERON:0002351 ! sinoatrial node [Term] id: CL:1000479 name: Purkinje myocyte of atrioventricular node def: "A Purkinje myocyte that is part of the atrioventricular node." [GOC:tfm] xref: FMA:83386 is_a: CL:0002068 {is_inferred="true"} ! Purkinje myocyte is_a: CL:1000410 ! myocyte of atrioventricular node intersection_of: CL:0002068 ! Purkinje myocyte intersection_of: part_of UBERON:0002352 ! atrioventricular node [Term] id: CL:1000482 name: myocardial endocrine cell of interventricular septum def: "A myocardial endocrine cell that is part of the interventricular septum." [GOC:tfm] xref: FMA:83390 is_a: CL:0002074 {is_inferred="true"} ! myocardial endocrine cell is_a: CL:2000022 ! cardiac septum cell intersection_of: CL:0002074 ! myocardial endocrine cell intersection_of: part_of UBERON:0002094 ! interventricular septum relationship: part_of UBERON:0002094 ! interventricular septum [Term] id: CL:1000488 name: cholangiocyte def: "An epithelial cell that is part of the bile duct. Cholangiocytes contribute to bile secretion via net release of bicarbonate and water. They are cuboidal epithelium in the small interlobular bile ducts, but become columnar and mucus secreting in larger bile ducts approaching the porta hepatis and the extrahepatic ducts." [GOC:tfm, PMID:16550043, PMID:18356246] subset: cellxgene_subset synonym: "epithelial cell of bile duct" EXACT [] xref: FMA:86481 is_a: CL:0000069 {is_inferred="true"} ! branched duct epithelial cell is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: CL:0000069 ! branched duct epithelial cell intersection_of: capable_of GO:0015106 ! bicarbonate transmembrane transporter activity intersection_of: part_of UBERON:0002394 ! bile duct relationship: develops_from CL:0005026 ! hepatoblast relationship: part_of UBERON:0002394 ! bile duct [Term] id: CL:1000490 name: mesothelial cell of peritoneum def: "A mesothelial cell that is part of the peritoneum." [GOC:tfm] synonym: "peritoneal mesothelial cell" EXACT [FMA:86736] xref: FMA:86736 is_a: CL:0000077 ! mesothelial cell intersection_of: CL:0000077 ! mesothelial cell intersection_of: part_of UBERON:0002358 ! peritoneum relationship: part_of UBERON:0002358 ! peritoneum [Term] id: CL:1000491 name: mesothelial cell of pleura def: "A mesothelial cell that is part of the pleura." [GOC:tfm] subset: cellxgene_subset synonym: "pleural mesothelial cell" EXACT [FMA:86737] xref: FMA:86737 is_a: CL:0000077 ! mesothelial cell is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure intersection_of: CL:0000077 ! mesothelial cell intersection_of: part_of UBERON:0000977 ! pleura relationship: part_of UBERON:0000977 ! pleura [Term] id: CL:1000492 name: mesothelial cell of parietal pleura def: "A mesothelial cell that is part of the parietal pleura." [GOC:tfm] xref: FMA:86738 is_a: CL:1000491 ! mesothelial cell of pleura intersection_of: CL:0000077 ! mesothelial cell intersection_of: part_of UBERON:0002400 ! parietal pleura relationship: part_of UBERON:0002400 ! parietal pleura [Term] id: CL:1000493 name: mesothelial cell of visceral pleura def: "A mesothelial cell that is part of the visceral pleura." [GOC:tfm] subset: cellxgene_subset subset: human_reference_atlas xref: FMA:86739 is_a: CL:0000082 ! epithelial cell of lung is_a: CL:1000491 ! mesothelial cell of pleura intersection_of: CL:0000077 ! mesothelial cell intersection_of: part_of UBERON:0002401 ! visceral pleura relationship: part_of UBERON:0002401 ! visceral pleura property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1000494 name: nephron tubule epithelial cell def: "An epithelial cell that is part of a nephron tubule." [GOC:tfm] comment: This needs to be further defined as a juxtamedullary nephron. Will request the juxtamedullary nephron tubule class from UBERON. subset: cellxgene_subset synonym: "kidney tubule epithelial cell" EXACT [] xref: FMA:86785 xref: KUPO:0001022 is_a: CL:1000449 ! epithelial cell of nephron is_a: CL:1000507 ! kidney tubule cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0004810 ! nephron tubule epithelium relationship: part_of UBERON:0004810 ! nephron tubule epithelium [Term] id: CL:1000497 name: kidney cell def: "A cell that is part of a kidney." [] subset: cellxgene_subset xref: KUPO:0001010 is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: part_of UBERON:0002113 ! kidney relationship: part_of UBERON:0002113 ! kidney [Term] id: CL:1000500 name: kidney interstitial cell def: "A cell that is part of kidney interstitium." [] subset: cellxgene_subset subset: kidney_upper_slim xref: KUPO:0001013 is_a: CL:1000497 ! kidney cell is_a: CL:4030031 ! interstitial cell intersection_of: CL:1000497 ! kidney cell intersection_of: part_of UBERON:0005215 ! kidney interstitium relationship: part_of UBERON:0005215 ! kidney interstitium [Term] id: CL:1000505 name: kidney pelvis cell def: "A cell that is part of a renal pelvis." [] subset: kidney_upper_slim xref: KUPO:0001018 is_a: CL:1000497 ! kidney cell intersection_of: CL:1000497 ! kidney cell intersection_of: part_of UBERON:0001224 ! renal pelvis relationship: part_of UBERON:0001224 ! renal pelvis [Term] id: CL:1000507 name: kidney tubule cell def: "A cell that is part of a nephron tubule." [] subset: kidney_upper_slim xref: KUPO:0001020 is_a: CL:1000497 ! kidney cell intersection_of: CL:1000497 ! kidney cell intersection_of: part_of UBERON:0001231 ! nephron tubule relationship: part_of UBERON:0001231 ! nephron tubule [Term] id: CL:1000549 name: kidney cortex collecting duct epithelial cell def: "An epithelial cell that is part of a cortical collecting duct." [] xref: KUPO:0001063 is_a: CL:0002584 ! renal cortical epithelial cell is_a: CL:1000454 ! kidney collecting duct epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0004203 ! cortical collecting duct relationship: part_of UBERON:0004203 ! cortical collecting duct [Term] id: CL:1000600 name: lower urinary tract cell xref: KUPO:0001115 is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: part_of UBERON:0001556 ! lower urinary tract relationship: part_of UBERON:0001556 ! lower urinary tract [Term] id: CL:1000601 name: ureteral cell xref: KUPO:0001116 is_a: CL:0000255 ! eukaryotic cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000000 ! cell intersection_of: part_of UBERON:0000056 ! ureter relationship: part_of UBERON:0000056 ! ureter [Term] id: CL:1000606 name: kidney nerve cell xref: KUPO:0001015 is_a: CL:1000500 ! kidney interstitial cell is_a: CL:2000032 ! peripheral nervous system neuron intersection_of: CL:0000540 ! neuron intersection_of: has_soma_location UBERON:0002113 ! kidney relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata) relationship: has_soma_location UBERON:0002113 ! kidney [Term] id: CL:1000681 name: kidney cortex interstitial cell xref: KUPO:0001091 is_a: CL:0002584 ! renal cortical epithelial cell is_a: CL:1000500 {is_inferred="true"} ! kidney interstitial cell intersection_of: CL:1000500 ! kidney interstitial cell intersection_of: part_of UBERON:0005270 ! renal cortex interstitium relationship: part_of UBERON:0005270 ! renal cortex interstitium [Term] id: CL:1000692 name: kidney interstitial fibroblast subset: cellxgene_subset subset: human_reference_atlas xref: KUPO:0001102 is_a: CL:0000057 ! fibroblast is_a: CL:1000500 ! kidney interstitial cell intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0005215 ! kidney interstitium property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1000702 name: kidney pelvis smooth muscle cell xref: KUPO:0001113 is_a: CL:0000192 {is_inferred="true"} ! smooth muscle cell is_a: CL:1000505 {is_inferred="true"} ! kidney pelvis cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0004227 ! kidney pelvis smooth muscle relationship: part_of UBERON:0004227 ! kidney pelvis smooth muscle [Term] id: CL:1000708 name: ureter adventitial cell subset: human_reference_atlas xref: KUPO:0001119 is_a: CL:0000115 ! endothelial cell is_a: CL:0002503 ! adventitial cell is_a: CL:1000601 {is_inferred="true"} ! ureteral cell intersection_of: CL:1000601 ! ureteral cell intersection_of: part_of UBERON:0001252 ! adventitia of ureter relationship: part_of UBERON:0001252 ! adventitia of ureter property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1000714 name: kidney cortex collecting duct principal cell subset: human_reference_atlas xref: KUPO:0001130 is_a: CL:1000549 {is_inferred="true"} ! kidney cortex collecting duct epithelial cell is_a: CL:1001431 ! kidney collecting duct principal cell intersection_of: CL:0005009 ! renal principal cell intersection_of: part_of UBERON:0004203 ! cortical collecting duct property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1000979 name: ureter smooth muscle cell xref: KUPO:0001118 is_a: CL:0000192 {is_inferred="true"} ! smooth muscle cell is_a: CL:1000601 {is_inferred="true"} ! ureteral cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0006855 ! muscular coat of ureter relationship: part_of UBERON:0006855 ! muscular coat of ureter [Term] id: CL:1001225 name: kidney collecting duct cell def: "A cell that is part of a collecting duct of renal tubule." [] subset: cellxgene_subset xref: KUPO:0001012 xref: Wikipedia:Kidney_collecting_duct_cell is_a: CL:1000497 ! kidney cell intersection_of: CL:1000497 ! kidney cell intersection_of: part_of UBERON:0001232 ! collecting duct of renal tubule relationship: part_of UBERON:0001232 ! collecting duct of renal tubule [Term] id: CL:1001319 name: bladder cell subset: cellxgene_subset subset: human_reference_atlas xref: KUPO:0001120 is_a: CL:1000600 ! lower urinary tract cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000000 ! cell intersection_of: part_of UBERON:0001255 ! urinary bladder relationship: part_of UBERON:0001255 ! urinary bladder property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1001320 name: urethra cell xref: KUPO:0001123 is_a: CL:1000600 ! lower urinary tract cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000000 ! cell intersection_of: part_of UBERON:0000057 ! urethra relationship: part_of UBERON:0000057 ! urethra [Term] id: CL:1001431 name: kidney collecting duct principal cell subset: cellxgene_subset subset: human_reference_atlas xref: KUPO:0001128 is_a: CL:0005009 {is_inferred="true"} ! renal principal cell is_a: CL:1000454 ! kidney collecting duct epithelial cell intersection_of: CL:0005009 ! renal principal cell intersection_of: part_of UBERON:0001232 ! collecting duct of renal tubule property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1001433 name: epithelial cell of exocrine pancreas def: "An epithelial cell of the exocrine pancreas." [GOC:tfm] subset: cellxgene_subset subset: human_reference_atlas synonym: "exocrine pancreas cell" EXACT [] xref: FMA:70986 is_a: CL:0000083 ! epithelial cell of pancreas intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0000017 ! exocrine pancreas relationship: part_of UBERON:0000017 ! exocrine pancreas property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1001516 name: intestinal enteroendocrine cell def: "The various hormone- or neurotransmitter-secreting cells present throughout the mucosa of the intestinal tract." [MP:0010802] subset: cellxgene_subset is_a: CL:0000164 ! enteroendocrine cell is_a: CL:0002563 ! intestinal epithelial cell intersection_of: CL:0000164 ! enteroendocrine cell intersection_of: part_of UBERON:0001242 ! intestinal mucosa [Term] id: CL:1001567 name: lung endothelial cell synonym: "endothelial cell of lung" RELATED [] synonym: "pulmonary vessel endothelial cell" RELATED [] is_a: CL:0000082 ! epithelial cell of lung is_a: CL:0002139 ! endothelial cell of vascular tree is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure intersection_of: CL:0002139 ! endothelial cell of vascular tree intersection_of: part_of UBERON:0002048 ! lung relationship: part_of UBERON:0000102 ! lung vasculature [Term] id: CL:1001568 name: pulmonary artery endothelial cell subset: cellxgene_subset subset: human_reference_atlas synonym: "PAEC cell" RELATED [BTO:0001141] xref: BTO:0001141 is_a: CL:1000413 ! endothelial cell of artery intersection_of: CL:0002139 ! endothelial cell of vascular tree intersection_of: part_of UBERON:0002012 ! pulmonary artery relationship: part_of UBERON:0005317 ! pulmonary artery endothelium property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1001572 name: colon endothelial cell def: "A vascular endothelial cell found in colon blood vessels." [https://orcid.org/0000-0001-5208-3432, NPX:PDR] synonym: "colon endothelial cells" RELATED OMO:0003004 [CALOHA:TS-2397] synonym: "colonic endothelial cell" RELATED [CALOHA:TS-2397] xref: CALOHA:TS-2397 is_a: CL:0000115 ! endothelial cell is_a: CL:0011108 ! colon epithelial cell is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure intersection_of: CL:0000115 ! endothelial cell intersection_of: part_of UBERON:0001155 ! colon relationship: part_of UBERON:0013695 ! colon endothelium [Term] id: CL:1001576 name: oral mucosa squamous cell def: "Squamous cell of oral epithelium." [NPX:PDR] synonym: "oral cavity mucosa squamous cell" RELATED [CALOHA:TS-1252] synonym: "oral cavity mucosa squamous epithelial cell" RELATED [CALOHA:TS-1252] synonym: "oral mucosa squamous epithelial cell" RELATED [CALOHA:TS-1252] synonym: "oral mucosa squamous epithelial cells" RELATED [CALOHA:TS-1252] xref: CALOHA:TS-1252 is_a: CL:0000076 ! squamous epithelial cell is_a: CL:0002251 ! epithelial cell of alimentary canal intersection_of: CL:0000076 ! squamous epithelial cell intersection_of: part_of UBERON:0002424 ! oral epithelium relationship: part_of UBERON:0002424 ! oral epithelium [Term] id: CL:1001588 name: colon glandular cell def: "Glandular cell of colon epithelium. Example: Goblet cells; enterocytes or absorptive cells; enteroendocrine and M cells." [NPX:PDR] synonym: "colon glandular cells" RELATED [CALOHA:TS-1274] xref: CALOHA:TS-1274 is_a: CL:0002658 ! glandular cell of the large intestine is_a: CL:0011108 ! colon epithelial cell intersection_of: CL:0000150 ! glandular epithelial cell intersection_of: part_of UBERON:0001155 ! colon [Term] id: CL:1001589 name: duodenum glandular cell def: "Glandular cell of duodenal epithelium. Example: Enterocytes, Goblet cells, enteroendocrine cells; Paneth cells; M cells; Brunner's gland cell." [NPX:PDR] subset: cellxgene_subset synonym: "duodenum glandular cells" RELATED [CALOHA:TS-1275] xref: CALOHA:TS-1275 is_a: CL:1001598 ! small intestine glandular cell intersection_of: CL:0000150 ! glandular epithelial cell intersection_of: part_of UBERON:0002114 ! duodenum relationship: part_of UBERON:0008346 ! duodenal epithelium [Term] id: CL:1001590 name: epididymis glandular cell def: "Glandular cell of epididymal epithelium." [NPX:PDR] synonym: "epididymal glandular cell" RELATED [CALOHA:TS-1276] synonym: "epididymis glandular cells" RELATED [CALOHA:TS-1276] xref: CALOHA:TS-1276 is_a: CL:0000068 ! duct epithelial cell is_a: CL:0000150 ! glandular epithelial cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000150 ! glandular epithelial cell intersection_of: part_of UBERON:0001301 ! epididymis relationship: part_of UBERON:0004544 ! epididymis epithelium [Term] id: CL:1001591 name: oviduct glandular cell name: oviduct secretory cell def: "Glandular cell of oviduct epithelium. Example: peg cells, ciliated cells." [HPA:HPA, NPX:PDR] synonym: "fallopian tube glandular cell" RELATED [CALOHA:TS-1277] synonym: "fallopian tube glandular cells" RELATED [CALOHA:TS-1277] synonym: "oviduct glandular cell" RELATED [] synonym: "uterine tube glandular cell" RELATED [CALOHA:TS-1277] xref: CALOHA:TS-1277 is_a: CL:0000150 ! glandular epithelial cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000150 ! glandular epithelial cell intersection_of: CL:1100001 ! secretory epithelial cell intersection_of: part_of UBERON:0000993 ! oviduct intersection_of: part_of UBERON:0000993 ! oviduct relationship: part_of UBERON:0004804 ! oviduct epithelium [Term] id: CL:1001592 name: gallbladder glandular cell def: "Glandular cell of gallbladder epithelium." [NPX:PDR] synonym: "gall bladder glandular cell" EXACT [FMA:7202] synonym: "gall bladder glandular cells" RELATED [CALOHA:TS-1278] synonym: "gallbladder glandular cells" RELATED [CALOHA:TS-1278] xref: CALOHA:TS-1278 is_a: CL:0000150 ! glandular epithelial cell is_a: CL:1000415 ! epithelial cell of gallbladder intersection_of: CL:0000150 ! glandular epithelial cell intersection_of: part_of UBERON:0002110 ! gallbladder relationship: part_of UBERON:0002029 ! epithelium of gall bladder [Term] id: CL:1001595 name: rectum glandular cell def: "Glandular cell of rectal epithelium. Example: Goblet cell; enterocytes or absorptive cells; enteroendocrine and M cells." [NPX:PDR] synonym: "rectal glandular cell" RELATED [CALOHA:TS-1281] synonym: "rectum glandular cells" RELATED [CALOHA:TS-1281] xref: CALOHA:TS-1281 is_a: CL:0002658 ! glandular cell of the large intestine intersection_of: CL:0000150 ! glandular epithelial cell intersection_of: part_of UBERON:0001052 ! rectum relationship: part_of UBERON:0003354 ! epithelium of rectum [Term] id: CL:1001597 name: seminal vesicle glandular cell def: "Glandular cell of seminal vesicle epithelium." [NPX:PDR] subset: cellxgene_subset synonym: "seminal vesicle glandular cells" RELATED [CALOHA:TS-1283] xref: CALOHA:TS-1283 is_a: CL:0000068 ! duct epithelial cell is_a: CL:0000150 ! glandular epithelial cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000150 ! glandular epithelial cell intersection_of: part_of UBERON:0000998 ! seminal vesicle relationship: part_of UBERON:0004805 ! seminal vesicle epithelium [Term] id: CL:1001598 name: small intestine glandular cell def: "A glandular cell found in the epithelium of the small intestine. Example: Enterocytes, Goblet cells, enteroendocrine cells; Paneth cells; M cells; Somatostatin-secreting Cells (D-cells) ." [NCI_Thesaurus:Small_Intestinal_Glandular_Cell, NPX:PDR] synonym: "small bowel glandular cell" RELATED [CALOHA:TS-1286] synonym: "small intestinal glandular cell" RELATED [CALOHA:TS-1286] synonym: "small intestine glandular cells" RELATED [CALOHA:TS-1286] xref: CALOHA:TS-1286 xref: FMA:86928 is_a: CL:0000150 ! glandular epithelial cell is_a: CL:0002254 ! epithelial cell of small intestine intersection_of: CL:0000150 ! glandular epithelial cell intersection_of: part_of UBERON:0002108 ! small intestine relationship: part_of UBERON:0001902 ! epithelium of small intestine [Term] id: CL:1001599 name: pancreas exocrine glandular cell def: "Glandular cell of exocrine pancreas epithelium. Example: pancreatic acinar cell, glandular cells in pancreatic canaliculi, glandular cells in pancreatic ducts." [HPA:HPA, NPX:PDR] subset: human_reference_atlas synonym: "exocrine pancreas glandular cell" RELATED [CALOHA:TS-1242] synonym: "pancreas exocrine glandular cells" RELATED [CALOHA:TS-1242] xref: BTO:0000028 xref: CALOHA:TS-1242 is_a: CL:0000150 ! glandular epithelial cell is_a: CL:0000152 ! exocrine cell is_a: CL:1001433 ! epithelial cell of exocrine pancreas intersection_of: CL:0000150 ! glandular epithelial cell intersection_of: part_of UBERON:0000017 ! exocrine pancreas relationship: part_of UBERON:0013697 ! exocrine pancreas epithelium property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1001609 name: muscle fibroblast def: "Fibroblast from muscle organ." [NPX:PDR] xref: CALOHA:TS-0643 is_a: CL:0000057 ! fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0001630 ! muscle organ relationship: part_of UBERON:0001630 ! muscle organ [Term] id: CL:1001610 name: bone marrow hematopoietic cell def: "Hematopoietic cells resident in the bone marrow. Include: hematopoietic stem cells (lymphoid stem cells and myeloid stem cells) and the precursor cells for thrombocytes, erythrocytes, basophils, neutrophils, eosinophils, monocytes and lymphocytes." [NPX:PDR] synonym: "bone marrow hematopoietic cells" RELATED [CALOHA:TS-2109] synonym: "bone marrow poietic cells" RELATED [CALOHA:TS-2109] xref: CALOHA:TS-2109 is_a: CL:0000988 ! hematopoietic cell is_a: CL:0002092 ! bone marrow cell intersection_of: CL:0000988 ! hematopoietic cell intersection_of: part_of UBERON:0002371 ! bone marrow relationship: part_of UBERON:0012429 ! hematopoietic tissue [Term] id: CL:1100001 name: secretory epithelial cell def: "An epithelial cell that is specialised for the synthesis and secretion of specific biomolecules." [https://orcid.org/0000-0002-7073-9172] is_a: CL:0000066 ! epithelial cell is_a: CL:0000151 ! secretory cell intersection_of: CL:0000066 ! epithelial cell intersection_of: CL:0000151 ! secretory cell property_value: term:contributor https://orcid.org/0000-0002-7073-9172 property_value: term:date "2024-07-21T09:24:44Z" xsd:dateTime [Term] id: CL:2000001 name: peripheral blood mononuclear cell def: "A leukocyte with a single non-segmented nucleus in the mature form found in the circulatory pool of blood." [GOC:TermGenie] subset: cellxgene_subset is_a: CL:0000080 ! circulating cell is_a: CL:0000842 ! mononuclear cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000842 ! mononuclear cell intersection_of: part_of UBERON:0000178 ! blood relationship: part_of UBERON:0000178 ! blood property_value: term:contributor https://www.wikidata.org/entity/Q35563349 creation_date: 2014-02-11T17:29:04Z [Term] id: CL:2000002 name: decidual cell def: "A specialized, enlarged, connective tissue cell of the decidua with enlarged nucleus, dense membrane‐bound secretory granules and cytoplasmic accumulation of glycogen and lipid droplets. These cells develop by the transformation of endometrial stromal cells during decidualization." [BTO:0002770, NCIT:C32429, PMID:30013421, PMID:30429548, Wiki:Decidual_cells&oldid=937509751, Wiki:Decidualization&oldid=908981933] subset: cellxgene_subset synonym: "decidua cell" EXACT [BTO:0002770, NCIT:C32429] synonym: "decidual stromal cell" EXACT [BTO:0005756, PMID:11719592] xref: BTO:0002770 xref: BTO:0005756 xref: NCIT:C32429 is_a: CL:0000349 ! extraembryonic cell is_a: CL:0000499 ! stromal cell is_a: UBERON:0004120 ! mesoderm-derived structure relationship: develops_from CL:0002255 ! stromal cell of endometrium relationship: part_of UBERON:0002450 ! decidua creation_date: 2014-02-20T23:06:41Z [Term] id: CL:2000008 name: microvascular endothelial cell def: "Any blood vessel endothelial cell that is part of a microvascular endothelium." [GOC:TermGenie] is_a: CL:0000071 ! blood vessel endothelial cell intersection_of: CL:0000071 ! blood vessel endothelial cell intersection_of: part_of UBERON:0008339 ! microvascular endothelium relationship: part_of UBERON:0008339 ! microvascular endothelium property_value: term:contributor https://www.wikidata.org/entity/Q35563349 creation_date: 2014-06-04T15:07:42Z [Term] id: CL:2000010 name: dermis blood vessel endothelial cell def: "Any blood vessel endothelial cell that is part of a dermis." [GOC:TermGenie] is_a: CL:0000071 ! blood vessel endothelial cell is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:0000071 ! blood vessel endothelial cell intersection_of: part_of UBERON:0002067 ! dermis relationship: part_of UBERON:0002067 ! dermis property_value: term:contributor https://www.wikidata.org/entity/Q35563349 creation_date: 2014-06-04T15:12:06Z [Term] id: CL:2000013 name: fibroblast of skin of abdomen def: "Any skin fibroblast that is part of a skin of abdomen." [GOC:TermGenie] is_a: CL:0002620 ! skin fibroblast intersection_of: CL:0002620 ! skin fibroblast intersection_of: part_of UBERON:0001416 ! skin of abdomen relationship: part_of UBERON:0001416 ! skin of abdomen property_value: term:contributor https://www.wikidata.org/entity/Q35563349 creation_date: 2014-06-04T15:18:16Z [Term] id: CL:2000016 name: lung microvascular endothelial cell def: "Any lung endothelial cell that is part of a microvascular endothelium." [GOC:TermGenie] subset: cellxgene_subset is_a: CL:1001567 ! lung endothelial cell is_a: CL:2000008 ! microvascular endothelial cell intersection_of: CL:1001567 ! lung endothelial cell intersection_of: part_of UBERON:0008339 ! microvascular endothelium property_value: term:contributor https://www.wikidata.org/entity/Q35563349 creation_date: 2014-06-04T16:00:56Z [Term] id: CL:2000019 name: compound eye photoreceptor cell def: "Any photoreceptor cell that is part of a compound eye." [GOC:TermGenie] xref: FBbt:00004211 is_a: CL:0000287 ! eye photoreceptor cell intersection_of: CL:0000210 ! photoreceptor cell intersection_of: part_of UBERON:0000018 ! compound eye relationship: part_of UBERON:0000018 ! compound eye property_value: term:contributor https://www.wikidata.org/entity/Q35563349 creation_date: 2014-06-24T23:16:45Z [Term] id: CL:2000020 name: inner cell mass cell def: "Any native cell that is part of a inner cell mass." [GOC:TermGenie] is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: part_of UBERON:0000087 ! inner cell mass relationship: part_of UBERON:0000087 ! inner cell mass property_value: term:contributor https://www.wikidata.org/entity/Q35563349 creation_date: 2014-06-24T23:16:53Z [Term] id: CL:2000022 name: cardiac septum cell def: "Any native cell that is part of a cardiac septum." [GOC:TermGenie] is_a: CL:0002494 ! cardiocyte is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000000 ! cell intersection_of: part_of UBERON:0002099 ! cardiac septum relationship: part_of UBERON:0002099 ! cardiac septum property_value: term:contributor https://www.wikidata.org/entity/Q35563349 creation_date: 2014-06-24T23:17:07Z [Term] id: CL:2000029 name: central nervous system neuron def: "Any neuron that is part of a central nervous system." [GOC:TermGenie] is_a: CL:0000540 ! neuron intersection_of: CL:0000540 ! neuron intersection_of: has_soma_location UBERON:0001017 ! central nervous system relationship: has_soma_location UBERON:0001017 ! central nervous system property_value: term:contributor https://www.wikidata.org/entity/Q35563349 creation_date: 2014-06-25T01:17:43Z [Term] id: CL:2000032 name: peripheral nervous system neuron def: "A neuron that is part of a peripheral nervous system." [GOC:TermGenie, ISBN:0721662544] subset: cellxgene_subset synonym: "peripheral neuron" EXACT [] synonym: "PNS neuron" EXACT [] xref: FMA:84664 is_a: CL:0000540 ! neuron intersection_of: CL:0000540 ! neuron intersection_of: has_soma_location UBERON:0000010 ! peripheral nervous system relationship: has_soma_location UBERON:0000010 ! peripheral nervous system property_value: term:contributor https://www.wikidata.org/entity/Q35563349 creation_date: 2014-06-25T02:28:17Z [Term] id: CL:2000040 name: bladder microvascular endothelial cell def: "Any microvascular endothelial cell that is part of a urinary bladder." [GOC:TermGenie] subset: human_reference_atlas is_a: CL:1001319 ! bladder cell is_a: CL:2000008 ! microvascular endothelial cell intersection_of: CL:2000008 ! microvascular endothelial cell intersection_of: part_of UBERON:0001255 ! urinary bladder property_value: RO:0002175 NCBITaxon:9606 property_value: term:contributor https://www.wikidata.org/entity/Q35563349 creation_date: 2014-07-09T00:04:47Z [Term] id: CL:2000042 name: embryonic fibroblast def: "Any fibroblast that is part of a embryo." [GOC:TermGenie] subset: cellxgene_subset is_a: CL:0000057 ! fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0000922 ! embryo property_value: term:contributor https://www.wikidata.org/entity/Q35563349 creation_date: 2014-07-09T00:12:00Z [Term] id: CL:2000044 name: brain microvascular endothelial cell def: "Any microvascular endothelial cell that is part of a brain." [GOC:TermGenie] is_a: CL:0002319 ! neural cell is_a: CL:2000008 ! microvascular endothelial cell is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:2000008 ! microvascular endothelial cell intersection_of: part_of UBERON:0000955 ! brain relationship: part_of UBERON:0000955 ! brain property_value: term:contributor https://www.wikidata.org/entity/Q35563349 creation_date: 2014-07-09T00:24:53Z [Term] id: CL:2000046 name: ventricular cardiac muscle cell def: "Any cardiac muscle cell that is part of a cardiac ventricle." [GOC:TermGenie] subset: cellxgene_subset is_a: CL:0000746 ! cardiac muscle cell intersection_of: CL:0000746 ! cardiac muscle cell intersection_of: part_of UBERON:0002082 ! cardiac ventricle relationship: part_of UBERON:0002082 ! cardiac ventricle property_value: term:contributor https://www.wikidata.org/entity/Q35563349 creation_date: 2014-08-12T20:50:28Z [Term] id: CL:2000047 name: brainstem motor neuron def: "Any motor neuron that is part of a brainstem." [GOC:TermGenie] is_a: CL:0000100 ! motor neuron is_a: CL:2000029 ! central nervous system neuron intersection_of: CL:0000100 ! motor neuron intersection_of: has_soma_location UBERON:0002298 ! brainstem relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata) relationship: has_soma_location UBERON:0002298 ! brainstem property_value: term:contributor https://www.wikidata.org/entity/Q35563349 creation_date: 2014-10-02T23:52:53Z [Term] id: CL:2000051 name: splenic fibroblast def: "Any fibroblast that is part of a spleen." [GOC:TermGenie] is_a: CL:0000057 ! fibroblast is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0002106 ! spleen relationship: part_of UBERON:0002106 ! spleen property_value: term:contributor https://www.wikidata.org/entity/Q35563349 creation_date: 2014-10-06T18:58:47Z [Term] id: CL:2000052 name: umbilical artery endothelial cell def: "Any endothelial cell of artery that is part of a umbilical cord." [GOC:TermGenie] comment: http://www.sciencellonline.com/site/productInformation.php?keyword=8010 is_a: CL:0000349 ! extraembryonic cell is_a: CL:1000413 ! endothelial cell of artery intersection_of: CL:1000413 ! endothelial cell of artery intersection_of: part_of UBERON:0002331 ! umbilical cord relationship: part_of UBERON:0002331 ! umbilical cord property_value: term:contributor https://www.wikidata.org/entity/Q35563349 creation_date: 2014-10-06T19:01:48Z [Term] id: CL:2000053 name: splenic endothelial cell def: "Any endothelial cell that is part of a spleen." [GOC:TermGenie] comment: http://www.sciencellonline.com/site/productInformation.php?keyword=5500 subset: human_reference_atlas is_a: CL:0000115 ! endothelial cell intersection_of: CL:0000115 ! endothelial cell intersection_of: part_of UBERON:0002106 ! spleen relationship: part_of UBERON:0002106 ! spleen property_value: RO:0002175 NCBITaxon:9606 property_value: term:contributor https://www.wikidata.org/entity/Q35563349 creation_date: 2014-10-06T19:06:04Z [Term] id: CL:2000055 name: liver dendritic cell def: "Any dendritic cell that is part of a liver." [GOC:TermGenie] comment: http://www.jleukbio.org/content/66/2/322.abstract subset: cellxgene_subset synonym: "hepatic dendritic cell" EXACT [] is_a: CL:0000451 ! dendritic cell is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: CL:0000451 ! dendritic cell intersection_of: part_of UBERON:0002107 ! liver relationship: part_of UBERON:0002107 ! liver property_value: term:contributor https://www.wikidata.org/entity/Q35563349 creation_date: 2014-10-06T19:16:11Z [Term] id: CL:2000061 name: placental amniotic mesenchymal stromal cell def: "Any mesenchymal stem cell that is part of a placenta." [GOC:TermGenie] comment: http://www.sciencellonline.com/site/productInformation.php?keyword=7140 subset: human_reference_atlas is_a: CL:0000134 ! mesenchymal stem cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000134 ! mesenchymal stem cell intersection_of: part_of UBERON:0001987 ! placenta relationship: part_of UBERON:0001987 ! placenta property_value: RO:0002175 NCBITaxon:9606 property_value: term:contributor https://www.wikidata.org/entity/Q35563349 creation_date: 2014-10-07T17:51:11Z [Term] id: CL:2000063 name: ovarian fibroblast def: "Any fibroblast that is part of a female gonad." [GOC:TermGenie] comment: http://www.sciencellonline.com/site/productInformation.php?keyword=7330 is_a: CL:0000057 ! fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0000992 ! ovary relationship: part_of UBERON:0000992 ! ovary property_value: term:contributor https://www.wikidata.org/entity/Q35563349 creation_date: 2014-10-07T17:57:42Z [Term] id: CL:2000064 name: ovarian surface epithelial cell def: "Any epithelial cell that is part of a female gonad." [GOC:TermGenie] comment: http://www.sciencellonline.com/site/productInformation.php?keyword=7310 subset: cellxgene_subset is_a: CL:0000066 ! epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0000992 ! ovary relationship: part_of UBERON:0000992 ! ovary property_value: term:contributor https://www.wikidata.org/entity/Q35563349 creation_date: 2014-10-07T17:59:13Z [Term] id: CL:2000065 name: ovarian microvascular endothelial cell def: "Any microvascular endothelial cell that is part of a female urethra." [GOC:TermGenie] comment: http://www.sciencellonline.com/site/productInformation.php?keyword=7300 is_a: CL:1000296 ! epithelial cell of urethra is_a: CL:2000008 ! microvascular endothelial cell intersection_of: CL:2000008 ! microvascular endothelial cell intersection_of: part_of UBERON:0001334 ! female urethra relationship: part_of UBERON:0001334 ! female urethra property_value: term:contributor https://www.wikidata.org/entity/Q35563349 creation_date: 2014-10-07T18:18:01Z [Term] id: CL:2000066 name: cardiac ventricle fibroblast def: "Any fibroblast that is part of a cardiac ventricle." [GOC:TermGenie] comment: http://www.sciencellonline.com/site/productInformation.php?keyword=6310 subset: human_reference_atlas is_a: CL:0002548 ! fibroblast of cardiac tissue intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0002082 ! cardiac ventricle relationship: part_of UBERON:0002082 ! cardiac ventricle property_value: RO:0002175 NCBITaxon:9606 property_value: term:contributor https://www.wikidata.org/entity/Q35563349 creation_date: 2014-10-07T18:35:38Z [Term] id: CL:2000067 name: cardiac atrium fibroblast def: "Any fibroblast that is part of a cardiac atrium." [GOC:TermGenie] comment: http://www.sciencellonline.com/site/productInformation.php?keyword=6320 subset: human_reference_atlas is_a: CL:0002548 ! fibroblast of cardiac tissue intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0002081 ! cardiac atrium relationship: part_of UBERON:0002081 ! cardiac atrium property_value: RO:0002175 NCBITaxon:9606 property_value: term:contributor https://www.wikidata.org/entity/Q35563349 creation_date: 2014-10-07T18:36:54Z [Term] id: CL:2000068 name: pericardium fibroblast def: "Any fibroblast that is part of a pericardium." [GOC:TermGenie] comment: http://www.sciencellonline.com/site/productInformation.php?keyword=6430 is_a: CL:0000057 ! fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0002407 ! pericardium relationship: part_of UBERON:0002407 ! pericardium property_value: term:contributor https://www.wikidata.org/entity/Q35563349 creation_date: 2014-10-07T18:38:06Z [Term] id: CL:2000069 name: gallbladder fibroblast def: "Any fibroblast that is part of a gallbladder." [GOC:TermGenie] comment: http://www.sciencellonline.com/site/productInformation.php?keyword=5430 is_a: CL:0000057 ! fibroblast is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0002110 ! gallbladder relationship: part_of UBERON:0002110 ! gallbladder property_value: term:contributor https://www.wikidata.org/entity/Q35563349 creation_date: 2014-10-07T18:41:43Z [Term] id: CL:2000070 name: optic choroid fibroblast def: "Any fibroblast that is part of a optic choroid." [GOC:TermGenie] comment: http://www.sciencellonline.com/site/productInformation.php?keyword=6620 is_a: CL:0000057 ! fibroblast is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0001776 ! optic choroid relationship: part_of UBERON:0001776 ! optic choroid property_value: term:contributor https://www.wikidata.org/entity/Q35563349 creation_date: 2014-10-07T18:50:43Z [Term] id: CL:2000072 name: adipose microvascular endothelial cell def: "Any microvascular endothelial cell that is part of a adipose tissue." [GOC:TermGenie] comment: http://www.sciencellonline.com/site/productInformation.php?keyword=7200 is_a: CL:0002320 ! connective tissue cell is_a: CL:2000008 ! microvascular endothelial cell intersection_of: CL:2000008 ! microvascular endothelial cell intersection_of: part_of UBERON:0001013 ! adipose tissue relationship: part_of UBERON:0001013 ! adipose tissue property_value: term:contributor https://www.wikidata.org/entity/Q35563349 creation_date: 2014-10-07T22:13:45Z [Term] id: CL:2000073 name: migratory cardiac neural crest cell def: "Any migratory neural crest cell that is part of a cardiac neural crest." [GOC:TermGenie] synonym: "cardiac neural crest cell" EXACT [PMID:33060096] is_a: CL:0000333 ! migratory neural crest cell intersection_of: CL:0000333 ! migratory neural crest cell intersection_of: part_of UBERON:0000095 ! cardiac neural crest relationship: part_of UBERON:0000095 ! cardiac neural crest property_value: term:contributor https://www.wikidata.org/entity/Q35563349 creation_date: 2014-11-05T01:18:43Z [Term] id: CL:2000074 name: splenocyte def: "Any leukocyte that is part of a spleen." [GOC:TermGenie] comment: Splenocytes is a vague term that refers to any one of the different white blood cell types in the spleen. This name is seen many references as such and is not explained further, necessitating a need for this terminology. is_a: CL:0000738 ! leukocyte is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000738 ! leukocyte intersection_of: part_of UBERON:0002106 ! spleen relationship: part_of UBERON:0002106 ! spleen property_value: term:contributor https://www.wikidata.org/entity/Q35563349 creation_date: 2014-11-05T01:26:50Z [Term] id: CL:2000080 name: mesenchymal stem cell of abdominal adipose tissue def: "Any mesenchymal stem cell of adipose tissue that is part of an abdomen." [GOC:TermGenie] synonym: "mesenchymal stem cell of abdominal adipose" EXACT [] is_a: CL:0002570 ! mesenchymal stem cell of adipose tissue intersection_of: CL:0002570 ! mesenchymal stem cell of adipose tissue intersection_of: part_of UBERON:0000916 ! abdomen relationship: part_of UBERON:0000916 ! abdomen property_value: term:contributor https://www.wikidata.org/entity/Q35563349 creation_date: 2014-12-02T19:10:34Z [Term] id: CL:2000085 name: mononuclear cell of umbilical cord def: "Any mononuclear cell that is part of a umbilical cord." [GOC:TermGenie] is_a: CL:0000349 ! extraembryonic cell is_a: CL:0000842 ! mononuclear cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000842 ! mononuclear cell intersection_of: part_of UBERON:0002331 ! umbilical cord relationship: part_of UBERON:0002331 ! umbilical cord property_value: term:contributor https://www.wikidata.org/entity/Q35563349 creation_date: 2014-12-02T20:14:16Z [Term] id: CL:2000091 name: endometrial microvascular endothelial cell def: "Any microvascular endothelial cell that is part of a endometrial blood vessel." [GOC:TermGenie] subset: human_reference_atlas is_a: CL:0009095 ! endothelial cell of uterus is_a: CL:2000008 ! microvascular endothelial cell intersection_of: CL:2000008 ! microvascular endothelial cell intersection_of: part_of UBERON:0015172 ! endometrial blood vessel relationship: part_of UBERON:0015172 ! endometrial blood vessel property_value: RO:0002175 NCBITaxon:9606 property_value: term:contributor https://www.wikidata.org/entity/Q35563349 creation_date: 2015-03-31T21:02:36Z [Term] id: CL:2000095 name: cord blood hematopoietic stem cell def: "Any hematopoietic stem cell that is part of a umbilical cord blood." [GOC:TermGenie] subset: cellxgene_subset is_a: CL:0002246 ! peripheral blood stem cell is_a: CL:0002352 ! gestational hematopoietic stem cell intersection_of: CL:0000037 ! hematopoietic stem cell intersection_of: part_of UBERON:0012168 ! umbilical cord blood relationship: part_of UBERON:0012168 ! umbilical cord blood property_value: term:contributor https://www.wikidata.org/entity/Q35563349 creation_date: 2015-05-26T18:58:34Z [Term] id: CL:3000000 name: ciliated epithelial cell of esophagus def: "A ciliated epithelial cell of the esophagus." [GOC:CellBLAST, PMID:29802404] is_a: CL:0000067 ! ciliated epithelial cell is_a: CL:0002252 ! epithelial cell of esophagus intersection_of: CL:0000067 ! ciliated epithelial cell intersection_of: part_of UBERON:0001976 ! epithelium of esophagus relationship: part_of UBERON:0001976 ! epithelium of esophagus property_value: term:contributor https://www.wikidata.org/entity/Q97529981 creation_date: 2019-02-09T16:40:30Z [Term] id: CL:3000004 name: peripheral sensory neuron def: "Peripheral sensory neuron." [GOC:CellBLAST, PMID:30096314] is_a: CL:0000101 ! sensory neuron is_a: CL:2000032 ! peripheral nervous system neuron intersection_of: CL:2000032 ! peripheral nervous system neuron intersection_of: capable_of GO:0050906 ! detection of stimulus involved in sensory perception property_value: term:contributor https://www.wikidata.org/entity/Q97529981 creation_date: 2019-02-25T19:34:33Z [Term] id: CL:4023072 name: brain vascular cell def: "A cell that is part of the brain vasculature." [DOI:10.1101/2022.10.12.511898] subset: human_reference_atlas is_a: CL:0002319 ! neural cell is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:0000000 ! cell intersection_of: part_of UBERON:0008998 ! vasculature of brain relationship: part_of UBERON:0008998 ! vasculature of brain property_value: RO:0002175 NCBITaxon:9606 property_value: term:contributor http://orcid.org/0000-0001-7258-9596 [Term] id: CL:4023079 name: midbrain-derived inhibitory neuron def: "A GABAergic inhibitory neuron that is derived from the midbrain." [DOI:10.1101/2022.10.12.511898] subset: human_reference_atlas is_a: CL:0000540 ! neuron is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:0000540 ! neuron intersection_of: develops_from UBERON:0001891 ! midbrain relationship: develops_from UBERON:0001891 ! midbrain property_value: RO:0002175 NCBITaxon:9606 property_value: term:contributor http://orcid.org/0000-0001-7258-9596 [Term] id: CL:4023168 name: somatosensory neuron def: "A neuron that is part of the somatic sensory system. Somatosensory neurons innervate the skin or integument to detect different types of thermal, chemical, and mechanical touch stimuli." [PMID:22865660] is_a: CL:0000540 ! neuron intersection_of: CL:0000540 ! neuron intersection_of: part_of UBERON:0003942 ! somatosensory system relationship: part_of UBERON:0003942 ! somatosensory system property_value: term:contributor http://orcid.org/0000-0001-7258-9596 [Term] id: CL:4028001 name: pulmonary capillary endothelial cell def: "Any capillary endothelial cell that is part of a lung." [] synonym: "lung capillary endothelial cell" EXACT [] is_a: CL:0002144 ! capillary endothelial cell is_a: CL:2000016 ! lung microvascular endothelial cell intersection_of: CL:0002144 ! capillary endothelial cell intersection_of: part_of UBERON:0002048 ! lung relationship: part_of UBERON:0016405 ! pulmonary capillary property_value: term:contributor https://orcid.org/0000-0002-3293-5463 creation_date: 2021-11-23T02:31:40Z [Term] id: CL:4030025 name: renal cortical fibroblast def: "A fibroblast that is located in the renal cortical interstitium." [PMID:10559635] comment: Renal cortical fibroblasts have key roles in mediating intercellular communication with neighboring/infiltrating cells and extracellular matrix and maintenance of renal tissue architecture. They additionally have an endocrine function in the production of epoetin. {xref="PMID:16230044"} synonym: "kidney cortical fibroblast" EXACT [] is_a: CL:1000681 ! kidney cortex interstitial cell is_a: CL:1000692 ! kidney interstitial fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0005270 ! renal cortex interstitium property_value: term:date "2022-07-05T15:50:17Z" xsd:dateTime [Term] id: CL:4030029 name: blood lymphocyte def: "A lymphocyte located in blood." [https://orcid.org/0000-0001-9990-8331] subset: blood_and_immune_upper_slim is_a: CL:0000542 ! lymphocyte is_a: CL:2000001 ! peripheral blood mononuclear cell intersection_of: CL:0000542 ! lymphocyte intersection_of: part_of UBERON:0000178 ! blood property_value: term:date "2022-11-04T14:40:00Z" xsd:dateTime [Term] id: CL:4030031 name: interstitial cell def: "Any cell that is located within the interstitium between the cells most prominent in defining a given tissue. \"Interstitial cell\" is a morphological term and refers to a variety of cells with differing origins and phenotypes." [PMID:24987007] is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: part_of UBERON:0005169 ! interstitial tissue relationship: part_of UBERON:0005169 ! interstitial tissue property_value: term:date "2022-11-30T14:35:08Z" xsd:dateTime [Term] id: CL:4030034 name: respiratory ciliated cell def: "A ciliated cell of the respiratory system. Ciliated cells are present in airway epithelium." [PMID:18757316, PMID:21364219] synonym: "ciliated cell of the respiratory tract" EXACT [] is_a: CL:0000064 ! ciliated cell is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: CL:0000064 ! ciliated cell intersection_of: part_of UBERON:0004802 ! respiratory tract epithelium relationship: part_of UBERON:0004802 ! respiratory tract epithelium property_value: term:date "2023-01-25T11:06:01Z" xsd:dateTime [Term] id: CL:4030040 name: endometrial ciliated epithelial cell def: "A ciliated cell of the endometrial epithelium. The cilia of this cell type help move mucus from glandular tissue of the endometrium." [doi:10.1038/s41591-020-1040-z, https://www.proteinatlas.org/humanproteome/single+cell+type/Glandular+epithelial+cells#endometrialciliatedcells] comment: In human samples, the expression of FOXJ1 protein, a regulator for motile cilia with epithelial lineage identity, has been noted. {xref="ttps://www.nature.com/articles/s41591-020-1040-z"} synonym: "ciliated cell of the endometrium" EXACT [] synonym: "ciliated cell of the uterus" BROAD [] synonym: "endometrium ciliated epithelial cell" EXACT [] synonym: "uterine ciliated cell" BROAD [] is_a: CL:0000067 ! ciliated epithelial cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000064 ! ciliated cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0004811 ! endometrium epithelium relationship: part_of UBERON:0004811 ! endometrium epithelium property_value: term:date "2023-02-09T11:25:14Z" xsd:dateTime [Term] id: CL:4030066 name: ureteric bud cell def: "An epithelial cell that is part of a ureteric bud. A ureteric bud cell has the potential to induce metanephric mesenchymal cells to proliferate and convert to epithelia that form renal tubules via: (1) the secretion of multiple diffusible growth factors that rescue renal progenitors from apoptosis and stimulate them to proliferate and (2) contact-dependent mechanisms that induce mesenchymal-epithelial conversion." [PMID:17133361, PMID:24183650, PMID:9374839] synonym: "UB cell" RELATED OMO:0003000 [PMID:24183650] is_a: CL:0000068 ! duct epithelial cell is_a: CL:0002518 ! kidney epithelial cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0000084 ! ureteric bud relationship: part_of UBERON:0000084 ! ureteric bud relationship: participates_in GO:2001013 {xref="PMID:9374839"} ! epithelial cell proliferation involved in renal tubule morphogenesis property_value: term:contributor "https://orcid.org/0000-0002-1425-877X" xsd:string property_value: term:date "2023-10-13T11:22:42Z" xsd:dateTime [Term] id: CL:4033008 name: vein endothelial cell of respiratory system def: "A(n) vein endothelial cell that is part of a(n) respiratory system." [PMID:34030460] subset: human_reference_atlas is_a: CL:0002543 ! vein endothelial cell intersection_of: CL:0002543 ! vein endothelial cell intersection_of: part_of UBERON:0001004 ! respiratory system relationship: part_of UBERON:0001004 ! respiratory system property_value: RO:0002175 NCBITaxon:9606 property_value: term:contributor https://orcid.org/0000-0001-6677-8489 [Term] id: CL:4033018 name: lung megakaryocyte def: "A megakaryocyte that is resident in the lung connective tissue." [PMID:33351116] subset: human_reference_atlas synonym: "lung MKs" RELATED OMO:0003004 [PMID:33351116] synonym: "lung resident megakaryocyte" EXACT [PMID:36524131] synonym: "lung-resident megakaryocyte" EXACT [PMID:36524131] synonym: "MKL" RELATED OMO:0003000 [PMID:36524131] is_a: CL:0000556 ! megakaryocyte is_a: CL:0002320 ! connective tissue cell is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure intersection_of: CL:0000556 ! megakaryocyte intersection_of: part_of UBERON:0000114 ! lung connective tissue relationship: part_of UBERON:0000114 ! lung connective tissue property_value: RO:0002175 NCBITaxon:9606 property_value: term:contributor https://orcid.org/0000-0001-6677-8489 property_value: term:contributor https://orcid.org/0000-0002-9185-3994 property_value: term:date "2023-03-16T11:31:23Z" xsd:dateTime [Term] id: CL:4033050 name: catecholaminergic neuron def: "A neuron that releases catecholamine as a neurotransmitter." [ISBN:0521442516, PMID:12094209] comment: Frequently used when describing the developing nervous system in zebrafish. A catecholaminergic neuron expresses tyrosine hydroxylase (TH), tyrosine hydroxylase 2 (TH2), aromatic amino acid decarboxylase (AADC), dopamine b-hydroxylase (DBH), and phenylethanolamine-N-methyl transferase (PEMT), which are enzymes necessary for catecholamine synthesis. {xref="https://orcid.org/0000-0002-2244-7917", xref="PMID:12128258", xref="PMID:10191060", xref="PMID:34880760"} is_a: CL:0000151 ! secretory cell is_a: CL:0000540 ! neuron intersection_of: CL:0000540 ! neuron intersection_of: capable_of GO:0160043 ! catecholamine secretion, neurotransmission relationship: capable_of GO:0160043 ! catecholamine secretion, neurotransmission property_value: term:contributor https://orcid.org/0000-0001-6677-8489 property_value: term:date "2023-05-18T12:07:45Z" xsd:dateTime [Term] id: CL:4033054 name: perivascular cell def: "A cell that is adjacent to a vessel. A perivascular cell plays a crucial role in maintaining vascular function and tissue homeostasis. This cell type regulates vessel integrity and flow dynamics." [PMID:24928499, PMID:27889329] is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: adjacent_to UBERON:0002049 ! vasculature relationship: adjacent_to UBERON:0002049 ! vasculature property_value: term:contributor https://orcid.org/0000-0001-6677-8489 property_value: term:date "2023-08-22T13:40:28Z" xsd:dateTime [Term] id: CL:4033061 name: endothelial cell of central vein of liver def: "An endothelial cell that is part of a central vein of liver." [PMID:28287163] synonym: "endothelial cell of central vein" BROAD [PMID:28287163] is_a: CL:0000115 ! endothelial cell is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure intersection_of: CL:0000115 ! endothelial cell intersection_of: part_of UBERON:0006841 ! central vein of liver relationship: part_of UBERON:0006841 ! central vein of liver property_value: term:contributor https://orcid.org/0000-0001-6677-8489 [Term] id: CL:4040004 name: mesenchymal stem cell of orbital adipose tissue def: "Any mesenchymal stem cell of adipose tissue that is part of an orbital region." [https://orcid.org/0000-0002-0819-0473] synonym: "OAMSC" EXACT [PMID:31377878] synonym: "orbital adipose-derived mesenchymal stem cell" EXACT [PMID:31377878] synonym: "Orbital ASCs" EXACT [PMID:30210548] is_a: CL:0002570 ! mesenchymal stem cell of adipose tissue intersection_of: CL:0002570 ! mesenchymal stem cell of adipose tissue intersection_of: part_of UBERON:0004088 ! orbital region relationship: part_of UBERON:0004088 ! orbital region property_value: term:contributor https://orcid.org/0000-0002-0819-0473 property_value: term:date "2023-09-18T10:43:00Z" xsd:dateTime [Term] id: GO:0000003 name: reproduction namespace: biological_process alt_id: GO:0019952 alt_id: GO:0050876 def: "The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms." [GOC:go_curators, GOC:isa_complete, GOC:jl, ISBN:0198506732] subset: goslim_agr subset: goslim_chembl subset: goslim_flybase_ribbon subset: goslim_pir subset: goslim_plant synonym: "reproductive physiological process" EXACT [] xref: Wikipedia:Reproduction is_a: GO:0008150 ! biological process [Term] id: GO:0000011 name: vacuole inheritance namespace: biological_process def: "The distribution of vacuoles into daughter cells after mitosis or meiosis, mediated by interactions between vacuoles and the cytoskeleton." [GOC:mcc, PMID:10873824, PMID:14616069] is_a: GO:0007033 ! vacuole organization is_a: GO:0048308 ! organelle inheritance intersection_of: GO:0048308 ! organelle inheritance intersection_of: results_in_distribution_of GO:0005773 ! vacuole relationship: results_in_distribution_of GO:0005773 ! vacuole property_value: RO:0002161 NCBITaxon:4896 [Term] id: GO:0000070 name: mitotic sister chromatid segregation namespace: biological_process alt_id: GO:0016359 def: "The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets." [GOC:ai, GOC:jl] subset: goslim_pombe synonym: "mitotic chromosome segregation" EXACT [] synonym: "mitotic sister-chromatid adhesion release" NARROW [] is_a: GO:0000819 ! sister chromatid segregation is_a: GO:1903047 ! mitotic cell cycle process intersection_of: GO:0098813 ! nuclear chromosome segregation intersection_of: part_of GO:0140014 ! mitotic nuclear division relationship: part_of GO:0140014 ! mitotic nuclear division [Term] id: GO:0000139 name: Golgi membrane namespace: cellular_component def: "The lipid bilayer surrounding any of the compartments of the Golgi apparatus." [GOC:mah] synonym: "Golgi apparatus membrane" EXACT [] is_a: GO:0098588 ! bounding membrane of organelle intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0005794 ! Golgi apparatus relationship: bounding_layer_of GO:0005794 ! Golgi apparatus relationship: part_of GO:0005794 ! Golgi apparatus [Term] id: GO:0000226 name: microtubule cytoskeleton organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins." [GOC:mah] subset: goslim_pombe synonym: "microtubule cytoskeleton organisation" EXACT [GOC:mah] synonym: "microtubule cytoskeleton organization and biogenesis" RELATED [GOC:mah] is_a: GO:0007010 ! cytoskeleton organization is_a: GO:0007017 ! microtubule-based process intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0015630 ! microtubule cytoskeleton relationship: results_in_organization_of GO:0015630 ! microtubule cytoskeleton property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23114" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23195" xsd:anyURI [Term] id: GO:0000228 name: nuclear chromosome namespace: cellular_component def: "A chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact." [GOC:dph, GOC:mah] subset: goslim_chembl subset: goslim_generic synonym: "nuclear interphase chromosome" NARROW [] is_a: GO:0005694 ! chromosome intersection_of: GO:0005694 ! chromosome intersection_of: part_of GO:0005634 ! nucleus relationship: part_of GO:0031981 ! nuclear lumen [Term] id: GO:0000271 name: polysaccharide biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." [GOC:go_curators] synonym: "glycan biosynthesis" EXACT [] synonym: "glycan biosynthetic process" EXACT [] synonym: "polysaccharide anabolism" EXACT [] synonym: "polysaccharide biosynthesis" EXACT [] synonym: "polysaccharide formation" EXACT [] synonym: "polysaccharide synthesis" EXACT [] is_a: GO:0005976 ! polysaccharide metabolic process is_a: GO:0009059 ! macromolecule biosynthetic process is_a: GO:0016051 ! carbohydrate biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:18154 ! polysaccharide relationship: has_primary_output CHEBI:18154 ! polysaccharide [Term] id: GO:0000272 name: polysaccharide catabolic process namespace: biological_process alt_id: GO:0044244 def: "The chemical reactions and pathways resulting in the breakdown of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." [PMID:33139480] synonym: "multicellular organismal polysaccharide catabolic process" NARROW [] synonym: "polysaccharide breakdown" EXACT [] synonym: "polysaccharide catabolism" EXACT [] synonym: "polysaccharide degradation" EXACT [] is_a: GO:0005976 ! polysaccharide metabolic process is_a: GO:0009057 ! macromolecule catabolic process is_a: GO:0016052 ! carbohydrate catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:18154 ! polysaccharide relationship: has_primary_input CHEBI:18154 ! polysaccharide [Term] id: GO:0000278 name: mitotic cell cycle namespace: biological_process alt_id: GO:0007067 def: "Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent." [GOC:mah, ISBN:0815316194, Reactome:69278] comment: Note that this term should not be confused with 'GO:0140014 ; mitotic nuclear division'. 'GO:0000278 ; mitotic cell cycle represents the entire mitotic cell cycle, while 'GO:0140014 ; mitotic nuclear division' specifically represents the actual nuclear division step of the mitotic cell cycle. subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_yeast synonym: "mitosis" RELATED [] xref: Wikipedia:Mitosis is_a: GO:0007049 ! cell cycle intersection_of: GO:0007049 ! cell cycle intersection_of: has_part GO:0140014 ! mitotic nuclear division relationship: has_part GO:0140014 ! mitotic nuclear division relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota [Term] id: GO:0000280 name: nuclear division namespace: biological_process def: "The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei." [GOC:mah] subset: goslim_pir synonym: "karyokinesis" RELATED [] is_a: GO:0048285 ! organelle fission intersection_of: GO:0048285 ! organelle fission intersection_of: results_in_fission_of GO:0005634 ! nucleus relationship: results_in_fission_of GO:0005634 ! nucleus [Term] id: GO:0000313 name: organellar ribosome namespace: cellular_component def: "A ribosome contained within a subcellular membrane-bounded organelle." [GOC:mah, GOC:mcc] is_a: GO:0005840 ! ribosome intersection_of: GO:0005840 ! ribosome intersection_of: part_of GO:0043226 ! organelle relationship: part_of GO:0043226 ! organelle [Term] id: GO:0000578 name: embryonic axis specification namespace: biological_process def: "The establishment, maintenance and elaboration of a pattern along a line or a point in an embryo." [GOC:dph, GOC:go_curators, GOC:sdb_2009, GOC:tb] synonym: "embryonic axis determination" RELATED [] is_a: GO:0009798 ! axis specification is_a: GO:0009880 ! embryonic pattern specification [Term] id: GO:0000740 name: nuclear membrane fusion namespace: biological_process def: "The joining of 2 or more lipid bilayer membranes that surround the nucleus." [GOC:elh] is_a: GO:0071763 ! nuclear membrane organization is_a: GO:0090174 ! organelle membrane fusion intersection_of: GO:0061025 ! membrane fusion intersection_of: results_in_fusion_of GO:0031965 ! nuclear membrane relationship: results_in_fusion_of GO:0031965 ! nuclear membrane [Term] id: GO:0000741 name: karyogamy namespace: biological_process alt_id: GO:0007335 def: "The creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei." [GOC:elh] synonym: "nuclear fusion" EXACT [] synonym: "nuclear fusion during karyogamy" EXACT [] xref: Wikipedia:Karyogamy is_a: GO:0006997 ! nucleus organization is_a: GO:0048284 ! organelle fusion intersection_of: GO:0048284 ! organelle fusion intersection_of: results_in_fusion_of GO:0005634 ! nucleus relationship: part_of GO:0006997 ! nucleus organization relationship: results_in_fusion_of GO:0005634 ! nucleus [Term] id: GO:0000768 name: syncytium formation by plasma membrane fusion namespace: biological_process def: "The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." [GOC:mtg_muscle, GOC:tb] synonym: "cell fusion" BROAD [] is_a: GO:0006949 ! syncytium formation is_a: GO:0140253 ! cell-cell fusion intersection_of: GO:0006949 ! syncytium formation intersection_of: has_part GO:0045026 ! plasma membrane fusion [Term] id: GO:0000785 name: chromatin namespace: cellular_component alt_id: GO:0000789 alt_id: GO:0000790 alt_id: GO:0005717 def: "The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome." [GOC:elh, PMID:20404130] comment: Chromosomes include parts that are not part of the chromatin. Examples include the kinetochore. synonym: "chromosome scaffold" RELATED [] synonym: "cytoplasmic chromatin" NARROW [] synonym: "nuclear chromatin" NARROW [] xref: NIF_Subcellular:sao1615953555 is_a: GO:0032993 ! protein-DNA complex relationship: part_of GO:0005694 ! chromosome [Term] id: GO:0000792 name: heterochromatin namespace: cellular_component alt_id: GO:0005720 alt_id: GO:0035328 def: "A compact and highly condensed form of chromatin that is refractory to transcription." [PMID:32017156] synonym: "nuclear heterochromatin" NARROW [] synonym: "transcriptionally inactive chromatin" EXACT [] synonym: "transcriptionally silent chromatin" EXACT [] xref: NIF_Subcellular:sao581845896 xref: Wikipedia:Heterochromatin is_a: GO:0000785 ! chromatin property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22355" xsd:anyURI [Term] id: GO:0000819 name: sister chromatid segregation namespace: biological_process def: "The cell cycle process in which sister chromatids are organized and then physically separated and apportioned to two or more sets." [GOC:ai, GOC:elh] is_a: GO:0051276 ! chromosome organization is_a: GO:0098813 ! nuclear chromosome segregation [Term] id: GO:0000902 name: cell morphogenesis namespace: biological_process alt_id: GO:0007148 alt_id: GO:0045790 alt_id: GO:0045791 def: "The developmental process in which the size or shape of a cell is generated and organized." [GOC:clt, GOC:dph, GOC:go_curators, GOC:tb] subset: goslim_chembl subset: goslim_drosophila subset: goslim_yeast synonym: "cellular morphogenesis" EXACT [] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of CL:0000000 ! cell relationship: results_in_morphogenesis_of CL:0000000 ! cell [Term] id: GO:0001101 name: response to acid chemical namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form." [GOC:go_curators, GOC:rn] comment: This term should be used to describe a response to a specific acid as a chemical. E.g., if an organism were responding to glutamate, then the response would be glutamate-specific; the organism is actually responding to the chemical structure of the anion portion of the dissociated acid. Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. If annotating experiments where an acid is playing a role as a proton donor, please annotate to GO:0010447 'response to acidic pH' instead. subset: gocheck_do_not_manually_annotate synonym: "response to acid" BROAD [] synonym: "response to acid anion" RELATED [] synonym: "response to oxoanion" RELATED [] is_a: GO:0042221 ! response to chemical [Term] id: GO:0001501 name: skeletal system development namespace: biological_process def: "The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton)." [GOC:dph, GOC:jid, GOC:tb] synonym: "skeletal development" EXACT [] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001434 ! skeletal system relationship: results_in_development_of UBERON:0001434 ! skeletal system [Term] id: GO:0001503 name: ossification namespace: biological_process def: "The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance." [GOC:mtg_mpo, PMID:17572649] comment: Note that this term does not have a 'developmental process' parent because ossification isn't necessarily developmental, can also occur as part of bone remodeling. Instead use 'ossification involved in bone maturation ; GO:0043931'. synonym: "bone biosynthesis" EXACT [] synonym: "bone formation" EXACT [] synonym: "osteogenesis" EXACT [] xref: Wikipedia:Ossification is_a: GO:0032501 ! multicellular organismal process intersection_of: GO:0032501 ! multicellular organismal process intersection_of: results_in_formation_of_anatomical_entity UBERON:0001474 ! bone element relationship: results_in_formation_of_anatomical_entity UBERON:0001474 ! bone element [Term] id: GO:0001508 name: action potential namespace: biological_process def: "A process in which membrane potential cycles through a depolarizing spike, triggered in response to depolarization above some threshold, followed by repolarization. This cycle is driven by the flow of ions through various voltage gated channels with different thresholds and ion specificities." [GOC:dph, GOC:go_curators, GOC:tb, ISBN:978-0-07-139011-8] comment: Action potentials typically propagate across excitable membranes. This class covers both action potentials that propagate and those that fail to do so. is_a: GO:0042391 ! regulation of membrane potential property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0001525 name: angiogenesis namespace: biological_process def: "Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels." [ISBN:0878932453] synonym: "blood vessel formation from pre-existing blood vessels" EXACT systematic_synonym [] xref: Wikipedia:Angiogenesis is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0001981 ! blood vessel relationship: part_of GO:0048514 ! blood vessel morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0001981 ! blood vessel [Term] id: GO:0001539 name: cilium or flagellum-dependent cell motility namespace: biological_process def: "Cell motility due to movement of eukaryotic cilia or bacterial-type flagella or archaeal-type flagella." [GOC:cilia, GOC:hjd, GOC:krc] comment: Note that we deem eukaryotic cilia and microtubule-based flagella to be equivalent, while the bacterial- and archaeal-type flagella have a different structure. The former are microtubule-based structures that lash back and forth and are present only in eukaryotes, while the latter achieve motility by rotation. Bacterial- and archaeal-type flagella are superficially similar but have a different molecular composition and fine structure. These three structures never co-exist in the same organism. Therefore, GO:0001539 'cilium or flagellum-dependent cell motility' is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term. Direct annotations to GO:0001539 'cilium or flagellum-dependent cell motility' may be amended during annotation QC. subset: gocheck_do_not_manually_annotate synonym: "ciliary or bacterial-type flagellar motility" RELATED [] synonym: "ciliary/flagellar motility" EXACT [] is_a: GO:0048870 ! cell motility [Term] id: GO:0001553 name: luteinization namespace: biological_process def: "The set of processes resulting in differentiation of theca and granulosa cells into luteal cells and in the formation of a corpus luteum after ovulation." [https://www.ncbi.nlm.nih.gov/books/NBK279054/] synonym: "luteal phase" RELATED [] xref: Wikipedia:Luteal_phase xref: Wikipedia:Luteinization is_a: GO:0022602 ! ovulation cycle process relationship: part_of GO:0008585 ! female gonad development [Term] id: GO:0001555 name: oocyte growth namespace: biological_process def: "The developmental growth process in which an oocyte irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present." [https://www.ncbi.nlm.nih.gov/books/NBK279054/] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0048588 ! developmental cell growth intersection_of: GO:0040007 ! growth intersection_of: results_in_growth_of CL:0000023 ! oocyte relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0048599 ! oocyte development relationship: results_in_growth_of CL:0000023 ! oocyte [Term] id: GO:0001556 name: oocyte maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for an oocyte to attain its fully functional state. Oocyte maturation commences after reinitiation of meiosis commonly starting with germinal vesicle breakdown, and continues up to the second meiotic arrest prior to fertilization." [GOC:devbiol, https://www.ncbi.nlm.nih.gov/books/NBK279054/] xref: Wikipedia:Oocyte_maturation is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0048469 ! cell maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of CL:0000023 ! oocyte relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0048599 ! oocyte development relationship: results_in_maturation_of CL:0000023 ! oocyte [Term] id: GO:0001558 name: regulation of cell growth namespace: biological_process def: "Any process that modulates the frequency, rate, extent or direction of cell growth." [GOC:go_curators] is_a: GO:0040008 ! regulation of growth is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0016049 ! cell growth relationship: regulates GO:0016049 ! cell growth [Term] id: GO:0001568 name: blood vessel development namespace: biological_process def: "The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood." [GOC:hjd, UBERON:0001981] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001981 ! blood vessel relationship: part_of GO:0001944 ! vasculature development relationship: results_in_development_of UBERON:0001981 ! blood vessel [Term] id: GO:0001569 name: branching involved in blood vessel morphogenesis namespace: biological_process def: "The process of coordinated growth and sprouting of blood vessels giving rise to the organized vascular system." [GOC:dph] synonym: "patterning of blood vessels" BROAD [GOC:dph] is_a: GO:0048754 ! branching morphogenesis of an epithelial tube intersection_of: GO:0048754 ! branching morphogenesis of an epithelial tube intersection_of: part_of GO:0048514 ! blood vessel morphogenesis relationship: part_of GO:0001525 ! angiogenesis [Term] id: GO:0001570 name: vasculogenesis namespace: biological_process def: "The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes." [PMID:8999798] synonym: "vascular morphogenesis" EXACT [] xref: Wikipedia:Vasculogenesis is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_formation_of_anatomical_entity UBERON:0001981 ! blood vessel relationship: part_of GO:0048514 ! blood vessel morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0001981 ! blood vessel [Term] id: GO:0001578 name: microtubule bundle formation namespace: biological_process def: "A process that results in a parallel arrangement of microtubules." [GOC:dph] synonym: "microtubule bundling" EXACT [] is_a: GO:0000226 ! microtubule cytoskeleton organization relationship: has_participant GO:0005874 ! microtubule relationship: results_in_formation_of_anatomical_entity GO:0097427 ! microtubule bundle [Term] id: GO:0001654 name: eye development namespace: biological_process alt_id: GO:0042460 def: "The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight." [GOC:jid, GOC:jl] xref: Wikipedia:Eye_development is_a: GO:0007423 ! sensory organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000970 ! eye relationship: part_of GO:0150063 ! visual system development relationship: results_in_development_of UBERON:0000970 ! eye [Term] id: GO:0001655 name: urogenital system development namespace: biological_process def: "The process whose specific outcome is the progression of the urogenital system over time, from its formation to the mature structure." [GOC:go_curators] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004122 ! genitourinary system relationship: has_part GO:0072001 ! renal system development relationship: results_in_development_of UBERON:0004122 ! genitourinary system property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22178" xsd:anyURI [Term] id: GO:0001656 name: metanephros development namespace: biological_process def: "The process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. In mammals, the metanephros is the excretory organ of the fetus, which develops into the mature kidney and is formed from the rear portion of the nephrogenic cord. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:bf, ISBN:0192800752] is_a: GO:0001822 ! kidney development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000081 ! metanephros relationship: results_in_development_of UBERON:0000081 ! metanephros [Term] id: GO:0001657 name: ureteric bud development namespace: biological_process def: "The process whose specific outcome is the progression of the ureteric bud over time, from its formation to the mature structure." [GOC:go_curators] is_a: GO:0072164 ! mesonephric tubule development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000084 ! ureteric bud relationship: results_in_development_of UBERON:0000084 ! ureteric bud [Term] id: GO:0001658 name: branching involved in ureteric bud morphogenesis namespace: biological_process def: "The process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules." [GOC:dph, PMID:16916378] synonym: "ureteric bud branching" EXACT [GOC:dph] is_a: GO:0048754 ! branching morphogenesis of an epithelial tube intersection_of: GO:0001763 ! morphogenesis of a branching structure intersection_of: part_of GO:0060675 ! ureteric bud morphogenesis relationship: part_of GO:0060675 ! ureteric bud morphogenesis [Term] id: GO:0001659 name: temperature homeostasis namespace: biological_process def: "A homeostatic process in which an organism modulates its internal body temperature." [GOC:jl] synonym: "thermoregulation" EXACT [GOC:dph, GOC:tb] xref: Wikipedia:Thermoregulation is_a: GO:0048871 ! multicellular organismal-level homeostasis [Term] id: GO:0001666 name: response to hypoxia namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level." [GOC:hjd] comment: Note that this term should not be confused with 'response to anoxia ; GO:0034059'. Note that in laboratory studies, hypoxia is typically studied at O2 concentrations ranging from 0.1 - 5%. synonym: "response to hypoxic stress" EXACT [] synonym: "response to intermittent hypoxia" NARROW [] synonym: "response to lowered oxygen tension" EXACT [] synonym: "response to sustained hypoxia" NARROW [] is_a: GO:0006950 ! response to stress is_a: GO:0036293 ! response to decreased oxygen levels [Term] id: GO:0001667 name: ameboidal-type cell migration namespace: biological_process def: "Cell migration that is accomplished by extension and retraction of a pseudopodium." [GOC:dph] comment: Note that this term refers to a mode of migration rather than to any particular cell type. synonym: "ameboid cell migration" EXACT [] synonym: "amoeboid cell migration" EXACT [] synonym: "amoeboidal cell migration" EXACT [] is_a: GO:0016477 ! cell migration [Term] id: GO:0001669 name: acrosomal vesicle namespace: cellular_component def: "A structure in the head of a spermatozoon that contains acid hydrolases, and is concerned with the breakdown of the outer membrane of the ovum during fertilization. It lies just beneath the plasma membrane and is derived from the lysosome." [ISBN:0124325653, ISBN:0198506732] synonym: "acrosomal granule" EXACT [GOC:sart] synonym: "acrosome" EXACT [GOC:dph] xref: Wikipedia:Acrosome is_a: GO:0030141 ! secretory granule relationship: part_of CL:0000019 ! sperm [Term] id: GO:0001673 name: male germ cell nucleus namespace: cellular_component alt_id: GO:0043081 def: "The nucleus of a male germ cell, a reproductive cell in males." [CL:0000015, GOC:hjd, GOC:mtg_sensu] synonym: "male germ-cell nucleus" EXACT [] is_a: GO:0043073 ! germ cell nucleus intersection_of: GO:0005634 ! nucleus intersection_of: part_of CL:0000015 ! male germ cell relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota relationship: part_of CL:0000015 ! male germ cell [Term] id: GO:0001674 name: female germ cell nucleus namespace: cellular_component alt_id: GO:0043080 def: "The nucleus of the female germ cell, a reproductive cell in females." [CL:0000021, GOC:hjd] synonym: "female germ-cell nucleus" EXACT [] is_a: GO:0043073 ! germ cell nucleus intersection_of: GO:0005634 ! nucleus intersection_of: part_of CL:0000021 ! female germ cell relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota relationship: part_of CL:0000021 ! female germ cell [Term] id: GO:0001675 name: acrosome assembly namespace: biological_process def: "The formation of the acrosome from the spermatid Golgi." [GOC:dph, GOC:hjd, GOC:tb] synonym: "acrosome formation" EXACT [GOC:dph, GOC:tb] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0010927 ! cellular component assembly involved in morphogenesis is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0033363 ! secretory granule organization is_a: GO:0070925 ! organelle assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0001669 ! acrosomal vesicle relationship: part_of GO:0007286 ! spermatid development relationship: results_in_assembly_of GO:0001669 ! acrosomal vesicle [Term] id: GO:0001677 name: formation of translation initiation ternary complex namespace: biological_process def: "Formation of a complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator)." [GOC:hjd] synonym: "translation initiation ternary complex assembly" EXACT [] is_a: GO:0022618 ! protein-RNA complex assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0044207 ! translation initiation ternary complex relationship: part_of GO:0006413 ! translational initiation relationship: results_in_assembly_of GO:0044207 ! translation initiation ternary complex [Term] id: GO:0001696 name: gastric acid secretion namespace: biological_process def: "The regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion." [GOC:hjd] synonym: "hydrochloric acid secretion" NARROW [] is_a: GO:0022600 ! digestive system process is_a: GO:0046717 ! acid secretion [Term] id: GO:0001700 name: embryonic development via the syncytial blastoderm namespace: biological_process def: "The process whose specific outcome is the progression of the embryo over time, from zygote formation through syncytial blastoderm to the hatching of the first instar larva. An example of this process is found in Drosophila melanogaster." [GOC:go_curators, GOC:mtg_sensu] is_a: GO:0009792 ! embryo development ending in birth or egg hatching relationship: in_taxon NCBITaxon:50557 {all_only="true"} ! Insecta relationship: only_in_taxon NCBITaxon:50557 ! Insecta [Term] id: GO:0001701 name: in utero embryonic development namespace: biological_process def: "The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus." [GOC:go_curators, GOC:mtg_sensu] is_a: GO:0043009 ! chordate embryonic development relationship: in_taxon NCBITaxon:32525 {all_only="true"} ! Theria relationship: only_in_taxon NCBITaxon:32525 ! Theria [Term] id: GO:0001702 name: gastrulation with mouth forming second namespace: biological_process alt_id: GO:0010003 alt_id: GO:0048276 def: "A gastrulation process in which the initial invagination becomes the anus and the mouth forms second." [GOC:go_curators, GOC:mtg_sensu] synonym: "deuterostomic gastrulation" EXACT [GOC:dph] is_a: GO:0007369 ! gastrulation relationship: in_taxon NCBITaxon:33511 {all_only="true"} ! Deuterostomia relationship: only_in_taxon NCBITaxon:33511 ! Deuterostomia [Term] id: GO:0001704 name: formation of primary germ layer namespace: biological_process def: "The formation of the ectoderm, mesoderm and endoderm during gastrulation." [GOC:go_curators] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0000923 ! germ layer relationship: part_of GO:0007369 ! gastrulation relationship: results_in_formation_of_anatomical_entity UBERON:0000923 ! germ layer [Term] id: GO:0001705 name: ectoderm formation namespace: biological_process def: "The formation of ectoderm during gastrulation." [GOC:go_curators] is_a: GO:0001704 ! formation of primary germ layer intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0000924 ! ectoderm relationship: part_of GO:0007398 ! ectoderm development relationship: results_in_formation_of_anatomical_entity UBERON:0000924 ! ectoderm [Term] id: GO:0001706 name: endoderm formation namespace: biological_process def: "The formation of the endoderm during gastrulation." [GOC:go_curators] synonym: "endoblast formation" NARROW [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0001704 ! formation of primary germ layer intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0000925 ! endoderm relationship: part_of GO:0007492 ! endoderm development relationship: results_in_formation_of_anatomical_entity UBERON:0000925 ! endoderm [Term] id: GO:0001707 name: mesoderm formation namespace: biological_process def: "The process that gives rise to the mesoderm. This process pertains to the initial formation of the structure from unspecified parts." [GOC:go_curators] is_a: GO:0001704 ! formation of primary germ layer intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0000926 ! mesoderm relationship: part_of GO:0048332 ! mesoderm morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0000926 ! mesoderm [Term] id: GO:0001743 name: lens placode formation namespace: biological_process def: "The initial developmental process that will lead to the formation of an eye." [GOC:dph] synonym: "optic placode formation" RELATED [] is_a: GO:0060788 ! ectodermal placode formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0003073 ! lens placode relationship: part_of GO:0048598 ! embryonic morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0003073 ! lens placode [Term] id: GO:0001745 name: compound eye morphogenesis namespace: biological_process def: "The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster." [GOC:dph, GOC:mtg_sensu] synonym: "insect-type retina morphogenesis" EXACT [PMID:11735386] is_a: GO:0048592 ! eye morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000018 ! compound eye relationship: in_taxon NCBITaxon:6656 {all_only="true"} ! Arthropoda relationship: only_in_taxon NCBITaxon:6656 ! Arthropoda relationship: part_of GO:0048749 ! compound eye development relationship: results_in_morphogenesis_of UBERON:0000018 ! compound eye [Term] id: GO:0001751 name: compound eye photoreceptor cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized features of an eye photoreceptor cell." [GOC:go_curators] is_a: GO:0001754 ! eye photoreceptor cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:2000019 ! compound eye photoreceptor cell relationship: part_of GO:0001745 ! compound eye morphogenesis relationship: results_in_acquisition_of_features_of CL:2000019 ! compound eye photoreceptor cell [Term] id: GO:0001754 name: eye photoreceptor cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell, as found in the eye, the primary visual organ of most organisms." [GOC:go_curators] is_a: GO:0046530 ! photoreceptor cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000287 ! eye photoreceptor cell relationship: part_of GO:0048592 ! eye morphogenesis relationship: results_in_acquisition_of_features_of CL:0000287 ! eye photoreceptor cell [Term] id: GO:0001755 name: neural crest cell migration namespace: biological_process def: "The characteristic movement of cells from the dorsal ridge of the neural tube to a variety of locations in a vertebrate embryo." [GOC:ascb_2009, GOC:dph, GOC:tb, ISBN:0878932437] is_a: GO:0090497 ! mesenchymal cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000333 ! migratory neural crest cell relationship: part_of GO:0014032 ! neural crest cell development relationship: results_in_movement_of CL:0000333 ! migratory neural crest cell [Term] id: GO:0001756 name: somitogenesis namespace: biological_process def: "The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo." [ISBN:0721662544] synonym: "formation of mesodermal clusters" EXACT systematic_synonym [] xref: Wikipedia:Somitogenesis is_a: GO:0009952 ! anterior/posterior pattern specification is_a: GO:0035282 ! segmentation is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0002329 ! somite relationship: part_of GO:0043009 ! chordate embryonic development relationship: part_of GO:0061053 ! somite development relationship: results_in_formation_of_anatomical_entity UBERON:0002329 ! somite [Term] id: GO:0001763 name: morphogenesis of a branching structure namespace: biological_process def: "The process in which the anatomical structures of branches are generated and organized. A branch is a division or offshoot from a main stem. Examples in animals would include blood vessels, nerves, lymphatics and other endothelial or epithelial tubes." [ISBN:0721662544] synonym: "branching morphogenesis" EXACT [GOC:dph] is_a: GO:0009653 ! anatomical structure morphogenesis is_a: GO:0032501 ! multicellular organismal process [Term] id: GO:0001764 name: neuron migration namespace: biological_process def: "The characteristic movement of an immature neuron from germinal zones to specific positions where they will reside as they mature." [CL:0000540, GOC:go_curators] synonym: "neuron chemotaxis" EXACT [] synonym: "neuron guidance" RELATED [] synonym: "neuronal migration" EXACT [] xref: Wikipedia:Neural_development#Neuron_migration xref: Wikipedia:Neuron_migration is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000540 ! neuron relationship: part_of GO:0048699 ! generation of neurons relationship: results_in_movement_of CL:0000540 ! neuron [Term] id: GO:0001767 name: establishment of lymphocyte polarity namespace: biological_process def: "The directed orientation of lymphocyte signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with an appropriate activating cell." [GOC:mgi_curators, PMID:11244041, PMID:12615889] synonym: "lymphocyte polarization" EXACT [] is_a: GO:0030010 ! establishment of cell polarity intersection_of: GO:0030010 ! establishment of cell polarity intersection_of: occurs_in CL:0000542 ! lymphocyte relationship: occurs_in CL:0000542 ! lymphocyte relationship: part_of GO:0046649 ! lymphocyte activation [Term] id: GO:0001768 name: establishment of T cell polarity namespace: biological_process def: "The directed orientation of T cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with antigen presenting cell." [GOC:mgi_curators, PMID:11244041, PMID:12615889] synonym: "establishment of T lymphocyte polarity" EXACT [] synonym: "establishment of T-cell polarity" EXACT [] synonym: "establishment of T-lymphocyte polarity" EXACT [] synonym: "T cell polarization" EXACT [] synonym: "T lymphocyte polarization" EXACT [] synonym: "T-cell polarization" EXACT [] is_a: GO:0001767 ! establishment of lymphocyte polarity intersection_of: GO:0030010 ! establishment of cell polarity intersection_of: occurs_in CL:0000084 ! T cell relationship: occurs_in CL:0000084 ! T cell relationship: part_of GO:0042110 ! T cell activation [Term] id: GO:0001775 name: cell activation namespace: biological_process def: "A multicellular organismal process by which exposure to an activating factor such as a cellular or soluble ligand results in a change in the morphology or behavior of a cell." [GOC:mgi_curators] subset: goslim_pir is_a: GO:0009987 ! cellular process is_a: GO:0032501 ! multicellular organismal process relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24416" xsd:anyURI [Term] id: GO:0001776 name: leukocyte homeostasis namespace: biological_process def: "The process of regulating the proliferation and elimination of cells of the immune system such that the total number of cells of a particular cell type within a whole or part of an organism is stable over time in the absence of an outside stimulus." [GOC:add, ISBN:0781735149] comment: Note that this term represents the return of immune system cell levels to stable numbers following an immune response as well as the proliferation and elimination of cells of the immune system required to maintain stable numbers in the absence of an outside stimulus. synonym: "immune cell homeostasis" EXACT [] synonym: "leucocyte homeostasis" EXACT [] is_a: GO:0002376 ! immune system process is_a: GO:0048872 ! homeostasis of number of cells intersection_of: GO:0048872 ! homeostasis of number of cells intersection_of: acts_on_population_of CL:0000738 ! leukocyte relationship: acts_on_population_of CL:0000738 ! leukocyte relationship: in_taxon NCBITaxon:7742 {all_only="true"} ! Vertebrata relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata [Term] id: GO:0001777 name: T cell homeostatic proliferation namespace: biological_process def: "The non-specific expansion of T cell populations within a whole or part of an organism to reach to a total number of T cells which will then remain stable over time in the absence of an external stimulus." [GOC:mgi_curators, ISBN:0781735149] synonym: "resting T cell proliferation" EXACT [] synonym: "resting T-cell proliferation" EXACT [] synonym: "T lymphocyte homeostatic proliferation" EXACT [] synonym: "T-cell homeostatic proliferation" EXACT [] synonym: "T-lymphocyte homeostatic proliferation" EXACT [] is_a: GO:0042098 ! T cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000084 ! T cell intersection_of: part_of GO:0042592 ! homeostatic process relationship: part_of GO:0043029 ! T cell homeostasis [Term] id: GO:0001816 name: cytokine production namespace: biological_process alt_id: GO:0042032 alt_id: GO:0042089 alt_id: GO:0042107 alt_id: GO:0050663 def: "The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:add, ISBN:0781735149] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms. subset: gocheck_do_not_annotate subset: goslim_pir synonym: "cytokine biosynthetic process" NARROW [] synonym: "cytokine metabolic process" NARROW [] synonym: "cytokine secretion" NARROW [] synonym: "interferon production" NARROW [GOC:add, GOC:mah] synonym: "interferon secretion" NARROW [GOC:add, GOC:mah] synonym: "interleukin production" NARROW [GOC:add, GOC:mah, http://wiki.geneontology.org/index.php/Why_isn%27t_interleukin_in_GO%3F] synonym: "interleukin secretion" NARROW [GOC:add, GOC:mah, http://wiki.geneontology.org/index.php/Why_isn%27t_interleukin_in_GO%3F] is_a: GO:0010467 ! gene expression is_a: GO:0032501 ! multicellular organismal process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19116" xsd:anyURI [Term] id: GO:0001817 name: regulation of cytokine production namespace: biological_process alt_id: GO:0042035 alt_id: GO:0050707 def: "Any process that modulates the frequency, rate, or extent of production of a cytokine." [GOC:add, ISBN:0781735149] synonym: "regulation of cytokine anabolism" EXACT [] synonym: "regulation of cytokine biosynthesis" EXACT [] synonym: "regulation of cytokine biosynthetic process" NARROW [] synonym: "regulation of cytokine formation" EXACT [] synonym: "regulation of cytokine secretion" NARROW [] synonym: "regulation of cytokine synthesis" EXACT [] is_a: GO:0010468 ! regulation of gene expression is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001816 ! cytokine production relationship: regulates GO:0001816 ! cytokine production [Term] id: GO:0001818 name: negative regulation of cytokine production namespace: biological_process alt_id: GO:0042036 alt_id: GO:0050710 def: "Any process that stops, prevents, or reduces the rate of production of a cytokine." [GOC:add, ISBN:0781735149] synonym: "down regulation of cytokine biosynthetic process" EXACT [] synonym: "down regulation of cytokine production" EXACT [] synonym: "down-regulation of cytokine biosynthetic process" EXACT [] synonym: "down-regulation of cytokine production" EXACT [] synonym: "downregulation of cytokine biosynthetic process" EXACT [] synonym: "downregulation of cytokine production" EXACT [] synonym: "inhibition of cytokine biosynthetic process" NARROW [] synonym: "inhibition of cytokine production" NARROW [] synonym: "negative regulation of cytokine anabolism" EXACT [] synonym: "negative regulation of cytokine biosynthesis" EXACT [] synonym: "negative regulation of cytokine biosynthetic process" NARROW [] synonym: "negative regulation of cytokine formation" EXACT [] synonym: "negative regulation of cytokine secretion" NARROW [] synonym: "negative regulation of cytokine synthesis" EXACT [] is_a: GO:0001817 ! regulation of cytokine production is_a: GO:0010629 ! negative regulation of gene expression is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001816 ! cytokine production relationship: negatively_regulates GO:0001816 ! cytokine production [Term] id: GO:0001819 name: positive regulation of cytokine production namespace: biological_process alt_id: GO:0042108 alt_id: GO:0050715 def: "Any process that activates or increases the frequency, rate or extent of production of a cytokine." [GOC:add, ISBN:0781735149] synonym: "activation of cytokine production" NARROW [] synonym: "positive regulation of cytokine biosynthetic process" NARROW [] synonym: "positive regulation of cytokine secretion" NARROW [] synonym: "stimulation of cytokine production" NARROW [] synonym: "up regulation of cytokine production" EXACT [] synonym: "up-regulation of cytokine production" EXACT [] synonym: "upregulation of cytokine production" EXACT [] is_a: GO:0001817 ! regulation of cytokine production is_a: GO:0010628 ! positive regulation of gene expression is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001816 ! cytokine production relationship: positively_regulates GO:0001816 ! cytokine production [Term] id: GO:0001820 name: serotonin secretion namespace: biological_process def: "The regulated release of serotonin by a cell. Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine synthesised in serotonergic neurons in the central nervous system, enterochromaffin cells in the gastrointestinal tract and some immune system cells." [GOC:ef, ISBN:0198506732, ISBN:0781735149] synonym: "5-HT secretion" EXACT [] synonym: "5-hydroxytryptamine secretion" EXACT [] synonym: "serotonin release" RELATED [GOC:tb] is_a: GO:0006837 ! serotonin transport is_a: GO:0023061 ! signal release intersection_of: GO:0046903 ! secretion intersection_of: has_primary_input CHEBI:350546 ! serotonin(1+) [Term] id: GO:0001822 name: kidney development namespace: biological_process def: "The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine." [GOC:dph, GOC:mtg_kidney_jan10, ISBN:0124020607, ISBN:0721662544] synonym: "nephrogenesis" RELATED [GOC:rph] xref: Wikipedia:Kidney_development is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002113 ! kidney relationship: part_of GO:0072001 ! renal system development relationship: results_in_development_of UBERON:0002113 ! kidney [Term] id: GO:0001823 name: mesonephros development namespace: biological_process def: "The process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. In mammals, the mesonephros is the second of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the mesonephros will form the mature kidney." [GOC:dph, ISBN:0124020607, ISBN:0721662544, PMID:10535314] synonym: "Wolffian body development" EXACT [GOC:dph] is_a: GO:0001822 ! kidney development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000080 ! mesonephros relationship: results_in_development_of UBERON:0000080 ! mesonephros [Term] id: GO:0001824 name: blastocyst development namespace: biological_process def: "The process whose specific outcome is the progression of the blastocyst over time, from its formation to the mature structure. The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm." [GOC:dph, ISBN:0124020607, ISBN:0198542771] comment: See also the Anatomical Dictionary for Mouse Development ontology terms 'TS5, embryo ; EMAP:23', 'TS5, inner cell mass ; EMAP:24' and 'TS5, trophectoderm; EMAP:28'. is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000358 ! blastocyst relationship: in_taxon NCBITaxon:32525 {all_only="true"} ! Theria relationship: only_in_taxon NCBITaxon:32525 ! Theria relationship: part_of GO:0001701 ! in utero embryonic development relationship: results_in_development_of UBERON:0000358 ! blastocyst [Term] id: GO:0001825 name: blastocyst formation namespace: biological_process def: "The initial formation of a blastocyst from a solid ball of cells known as a morula." [GOC:dph, ISBN:0124020607, ISBN:0198542771] comment: See also the Anatomical Dictionary for Mouse Development ontology term 'TS3, compacted morula ; EMAP:9'. is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0000358 ! blastocyst relationship: part_of GO:0001824 ! blastocyst development relationship: results_in_formation_of_anatomical_entity UBERON:0000358 ! blastocyst [Term] id: GO:0001826 name: inner cell mass cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of an inner cell mass cell." [GOC:dph, ISBN:0124020607, ISBN:0198542771] comment: See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, inner cell mass ; EMAP:14'. is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:2000020 ! inner cell mass cell relationship: part_of GO:0001825 ! blastocyst formation relationship: results_in_acquisition_of_features_of CL:2000020 ! inner cell mass cell [Term] id: GO:0001829 name: trophectodermal cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized features of a trophectoderm cell." [GOC:dph, ISBN:0124020607, ISBN:0198542771] comment: See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19'. synonym: "trophectoderm cell differentiation" EXACT [] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:1000274 ! trophectodermal cell relationship: part_of GO:0001825 ! blastocyst formation relationship: results_in_acquisition_of_features_of CL:1000274 ! trophectodermal cell [Term] id: GO:0001831 name: trophectodermal cellular morphogenesis namespace: biological_process def: "The morphogenesis of trophectoderm cells." [GOC:dph, ISBN:0124020607, ISBN:0198542771] comment: See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19', 'TS5, trophectoderm ; EMAP:28' and 'TS6, trophectoderm ; EMAP:39'. synonym: "trophectoderm cellular morphogenesis" EXACT [] is_a: GO:0000902 ! cell morphogenesis is_a: GO:0048598 ! embryonic morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of CL:1000274 ! trophectodermal cell relationship: part_of GO:0001829 ! trophectodermal cell differentiation relationship: results_in_morphogenesis_of CL:1000274 ! trophectodermal cell [Term] id: GO:0001832 name: blastocyst growth namespace: biological_process def: "An increase in size of a blastocyst due to expansion of the blastocoelic cavity cell shape changes and cell proliferation." [GOC:dph, ISBN:0124020607, ISBN:0198542771] comment: See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, blastocoelic cavity ; EMAP:17', 'TS5, blastocoelic cavity ; EMAP:27' and 'TS6, blastocoelic cavity ; EMAP:36'. is_a: GO:0048589 ! developmental growth intersection_of: GO:0040007 ! growth intersection_of: results_in_growth_of UBERON:0000358 ! blastocyst relationship: part_of GO:0001824 ! blastocyst development relationship: results_in_growth_of UBERON:0000358 ! blastocyst [Term] id: GO:0001833 name: inner cell mass cell proliferation namespace: biological_process def: "The proliferation of cells in the inner cell mass." [GOC:dph, GOC:isa_complete, ISBN:0124020607, ISBN:0198542771] comment: See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, inner cell mass ; EMAP:14' and 'TS5, inner cell mass ; EMAP:24'. is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:2000020 ! inner cell mass cell relationship: acts_on_population_of CL:2000020 ! inner cell mass cell relationship: part_of GO:0001832 ! blastocyst growth [Term] id: GO:0001834 name: trophectodermal cell proliferation namespace: biological_process def: "The proliferation of cells in the trophectoderm." [GOC:dph, ISBN:0124020607, ISBN:0198542771] comment: See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19', 'TS5, trophectoderm ; EMAP:28' and 'TS6, trophectoderm ; EMAP:39'. synonym: "trophectoderm cell proliferation" EXACT [] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:1000274 ! trophectodermal cell relationship: acts_on_population_of CL:1000274 ! trophectodermal cell relationship: part_of GO:0001832 ! blastocyst growth [Term] id: GO:0001837 name: epithelial to mesenchymal transition namespace: biological_process def: "A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell." [GOC:dph, PMID:14701881] synonym: "EMT" EXACT [] synonym: "epithelial-mesenchymal transition" EXACT [] synonym: "mesenchymal cell differentiation from epithelial cell" EXACT [GOC:BHF, GOC:dph, GOC:rl] is_a: GO:0048762 ! mesenchymal cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: has_primary_input CL:0000066 ! epithelial cell intersection_of: results_in_acquisition_of_features_of CL:0008019 ! mesenchymal cell relationship: has_primary_input CL:0000066 ! epithelial cell [Term] id: GO:0001838 name: embryonic epithelial tube formation namespace: biological_process def: "The morphogenesis of an embryonic epithelium into a tube-shaped structure." [GOC:dph, ISBN:0824072820] is_a: GO:0072175 ! epithelial tube formation relationship: part_of GO:0016331 ! morphogenesis of embryonic epithelium [Term] id: GO:0001839 name: neural plate morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the neural plate are generated and organized. The neural plate is a specialized region of columnar epithelial cells in the dorsal ectoderm that will give rise to nervous system tissue." [GOC:dph, ISBN:0878932437] is_a: GO:0016331 ! morphogenesis of embryonic epithelium intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003075 ! neural plate relationship: part_of GO:0001840 ! neural plate development relationship: results_in_morphogenesis_of UBERON:0003075 ! neural plate [Term] id: GO:0001840 name: neural plate development namespace: biological_process def: "The process whose specific outcome is the progression of the neural plate over time, from its formation to the mature structure. The neural plate is a flat, thickened layer of ectodermal cells. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system." [GOC:dph, GOC:ef, ISBN:0878932437, ISBN:0878932585] is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003075 ! neural plate relationship: part_of GO:0043009 ! chordate embryonic development relationship: results_in_development_of UBERON:0003075 ! neural plate [Term] id: GO:0001841 name: neural tube formation namespace: biological_process alt_id: GO:0001679 def: "The formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system." [GOC:dph, ISBN:0878932437] synonym: "neural tube morphogenesis" EXACT [GOC:dph] synonym: "neurulation" EXACT [] xref: Wikipedia:Neurulation is_a: GO:0001838 ! embryonic epithelial tube formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0001049 ! neural tube relationship: part_of GO:0021915 ! neural tube development relationship: results_in_formation_of_anatomical_entity UBERON:0001049 ! neural tube [Term] id: GO:0001842 name: neural fold formation namespace: biological_process def: "The process in which the neural fold is formed. The edges of the neural plate thicken and move up to form a U-shaped structure called the neural groove." [GOC:dph, ISBN:0878932437] synonym: "neural groove formation" RELATED [GOC:dph] is_a: GO:0016331 ! morphogenesis of embryonic epithelium is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis is_a: GO:0060571 ! morphogenesis of an epithelial fold intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0005062 ! neural fold relationship: part_of GO:0014020 ! primary neural tube formation relationship: results_in_formation_of_anatomical_entity UBERON:0005062 ! neural fold [Term] id: GO:0001878 name: response to yeast namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a yeast species." [PMID:14707091] comment: defined as response to Saccharomycotina (true yeasts). This excludes fission yeast. is_a: GO:0009620 ! response to fungus intersection_of: GO:0050896 ! response to stimulus intersection_of: has_primary_input NCBITaxon:147537 ! Saccharomycotina relationship: has_primary_input NCBITaxon:147537 ! Saccharomycotina [Term] id: GO:0001885 name: endothelial cell development namespace: biological_process def: "The progression of an endothelial cell over time, from its formation to the mature structure." [GOC:dph] is_a: GO:0002064 ! epithelial cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000115 ! endothelial cell relationship: part_of GO:0045446 ! endothelial cell differentiation relationship: results_in_development_of CL:0000115 ! endothelial cell [Term] id: GO:0001886 name: endothelial cell morphogenesis namespace: biological_process def: "The change in form (cell shape and size) that occurs during the differentiation of an endothelial cell." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0003382 ! epithelial cell morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of CL:0000115 ! endothelial cell relationship: part_of GO:0001885 ! endothelial cell development relationship: results_in_morphogenesis_of CL:0000115 ! endothelial cell [Term] id: GO:0001889 name: liver development namespace: biological_process def: "The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes." [GOC:add, ISBN:068340007X] is_a: GO:0048732 ! gland development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002107 ! liver relationship: part_of GO:0061008 ! hepaticobiliary system development relationship: results_in_development_of UBERON:0002107 ! liver [Term] id: GO:0001890 name: placenta development namespace: biological_process def: "The process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin." [GOC:add, ISBN:068340007X] synonym: "placental development" EXACT [] synonym: "placentation" EXACT [GOC:dph, GOC:tb] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001987 ! placenta relationship: in_taxon NCBITaxon:32525 {all_only="true"} ! Theria relationship: only_in_taxon NCBITaxon:32525 ! Theria relationship: results_in_development_of UBERON:0001987 ! placenta [Term] id: GO:0001892 name: embryonic placenta development namespace: biological_process def: "The embryonically driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin." [GOC:add, ISBN:068340007X] synonym: "fetal placenta development" EXACT [GOC:dph] is_a: GO:0048568 ! embryonic organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0007106 ! chorionic villus relationship: part_of GO:0001701 ! in utero embryonic development relationship: part_of GO:0001890 ! placenta development relationship: results_in_development_of UBERON:0007106 ! chorionic villus [Term] id: GO:0001893 name: maternal placenta development namespace: biological_process def: "Maternally driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin." [GOC:add, ISBN:068340007X] synonym: "decidua development" RELATED [GOC:dph] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0048856 ! anatomical structure development is_a: GO:0060135 ! maternal process involved in female pregnancy intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002450 ! decidua relationship: part_of GO:0001890 ! placenta development relationship: results_in_development_of UBERON:0002450 ! decidua [Term] id: GO:0001935 name: endothelial cell proliferation namespace: biological_process def: "The multiplication or reproduction of endothelial cells, resulting in the expansion of a cell population. Endothelial cells are thin flattened cells which line the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium." [GOC:add, ISBN:0781735149] is_a: GO:0050673 ! epithelial cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000115 ! endothelial cell relationship: acts_on_population_of CL:0000115 ! endothelial cell [Term] id: GO:0001936 name: regulation of endothelial cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of endothelial cell proliferation." [GOC:add] is_a: GO:0050678 ! regulation of epithelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001935 ! endothelial cell proliferation relationship: regulates GO:0001935 ! endothelial cell proliferation [Term] id: GO:0001937 name: negative regulation of endothelial cell proliferation namespace: biological_process def: "Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation." [GOC:add] synonym: "down regulation of endothelial cell proliferation" EXACT [] synonym: "down-regulation of endothelial cell proliferation" EXACT [] synonym: "downregulation of endothelial cell proliferation" EXACT [] synonym: "inhibition of endothelial cell proliferation" NARROW [] is_a: GO:0001936 ! regulation of endothelial cell proliferation is_a: GO:0050680 ! negative regulation of epithelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001935 ! endothelial cell proliferation relationship: negatively_regulates GO:0001935 ! endothelial cell proliferation [Term] id: GO:0001938 name: positive regulation of endothelial cell proliferation namespace: biological_process def: "Any process that activates or increases the rate or extent of endothelial cell proliferation." [GOC:add] synonym: "activation of endothelial cell proliferation" NARROW [] synonym: "stimulation of endothelial cell proliferation" NARROW [] synonym: "up regulation of endothelial cell proliferation" EXACT [] synonym: "up-regulation of endothelial cell proliferation" EXACT [] synonym: "upregulation of endothelial cell proliferation" EXACT [] is_a: GO:0001936 ! regulation of endothelial cell proliferation is_a: GO:0050679 ! positive regulation of epithelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001935 ! endothelial cell proliferation relationship: positively_regulates GO:0001935 ! endothelial cell proliferation [Term] id: GO:0001940 name: male pronucleus namespace: cellular_component def: "The pronucleus originating from the spermatozoa that was involved in fertilization." [GOC:hjd, ISBN:0198506732] is_a: GO:0045120 ! pronucleus [Term] id: GO:0001944 name: vasculature development namespace: biological_process def: "The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism." [GOC:dph, UBERON:0002409] synonym: "vascular system development" RELATED [] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002049 ! vasculature relationship: part_of GO:0072359 ! circulatory system development relationship: results_in_development_of UBERON:0002049 ! vasculature [Term] id: GO:0001955 name: blood vessel maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for a blood vessel to attain its fully functional state." [GOC:dph] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of UBERON:0001981 ! blood vessel relationship: part_of GO:0001568 ! blood vessel development relationship: results_in_maturation_of UBERON:0001981 ! blood vessel [Term] id: GO:0001956 name: positive regulation of neurotransmitter secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of a neurotransmitter." [GOC:hjd] synonym: "activation of neurotransmitter secretion" NARROW [] synonym: "stimulation of neurotransmitter secretion" NARROW [] synonym: "up regulation of neurotransmitter secretion" EXACT [] synonym: "up-regulation of neurotransmitter secretion" EXACT [] synonym: "upregulation of neurotransmitter secretion" EXACT [] is_a: GO:0046928 ! regulation of neurotransmitter secretion is_a: GO:0050806 ! positive regulation of synaptic transmission is_a: GO:0051590 ! positive regulation of neurotransmitter transport is_a: GO:1903532 ! positive regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007269 ! neurotransmitter secretion relationship: positively_regulates GO:0007269 ! neurotransmitter secretion [Term] id: GO:0001957 name: intramembranous ossification namespace: biological_process def: "Direct ossification that occurs within mesenchyme or an accumulation of relatively unspecialized cells." [ISBN:0878932437] comment: An instance of intramembranous ossification may also be classified as metaplastic; the former classifies based on tissue type location, and the latter based on mechanism/cell division. synonym: "dermal ossification" NARROW [GO_REF:0000034] synonym: "intramembranous bone ossification" RELATED [GOC:cjm] xref: Wikipedia:Intramembranous_ossification is_a: GO:0036072 ! direct ossification [Term] id: GO:0002009 name: morphogenesis of an epithelium namespace: biological_process def: "The process in which the anatomical structures of epithelia are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube." [GOC:dph, GOC:jl, GOC:tb, ISBN:0198506732] synonym: "epithelium morphogenesis" EXACT [] is_a: GO:0048729 ! tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000483 ! epithelium relationship: part_of GO:0060429 ! epithelium development relationship: results_in_morphogenesis_of UBERON:0000483 ! epithelium [Term] id: GO:0002011 name: morphogenesis of an epithelial sheet namespace: biological_process def: "The process in which the anatomical structures of an epithelial sheet are generated and organized. An epithelial sheet is a flat surface consisting of closely packed epithelial cells." [GOC:jl] is_a: GO:0002009 ! morphogenesis of an epithelium intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0010136 ! epithelial sheet relationship: results_in_morphogenesis_of UBERON:0010136 ! epithelial sheet [Term] id: GO:0002027 name: regulation of heart rate namespace: biological_process def: "Any process that modulates the frequency or rate of heart contraction." [GOC:dph, GOC:tb, PMID:10358008] synonym: "cardiac chronotropy" EXACT [GOC:dph, GOC:tb] synonym: "regulation of heart contraction rate" EXACT [] synonym: "regulation of rate of heart contraction" EXACT [] is_a: GO:0008016 ! regulation of heart contraction [Term] id: GO:0002028 name: regulation of sodium ion transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph] synonym: "regulation of Na+ transport" EXACT [] synonym: "regulation of sodium transport" EXACT [] is_a: GO:0010959 ! regulation of metal ion transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006814 ! sodium ion transport relationship: regulates GO:0006814 ! sodium ion transport [Term] id: GO:0002052 name: positive regulation of neuroblast proliferation namespace: biological_process def: "Any process that activates or increases the rate of neuroblast proliferation." [GOC:dph] synonym: "activation of neuroblast proliferation" NARROW [] synonym: "stimulation of neuroblast proliferation" NARROW [] synonym: "up regulation of neuroblast proliferation" EXACT [] synonym: "up-regulation of neuroblast proliferation" EXACT [] synonym: "upregulation of neuroblast proliferation" EXACT [] is_a: GO:0050769 ! positive regulation of neurogenesis is_a: GO:1902692 ! regulation of neuroblast proliferation is_a: GO:2000179 ! positive regulation of neural precursor cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007405 ! neuroblast proliferation relationship: positively_regulates GO:0007405 ! neuroblast proliferation [Term] id: GO:0002053 name: positive regulation of mesenchymal cell proliferation namespace: biological_process def: "The process of activating or increasing the rate or extent of mesenchymal cell proliferation. Mesenchymal cells are loosely organized embryonic cells." [GOC:dph] synonym: "activation of mesenchymal cell proliferation" NARROW [] synonym: "stimulation of mesenchymal cell proliferation" NARROW [] synonym: "up regulation of mesenchymal cell proliferation" EXACT [] synonym: "up-regulation of mesenchymal cell proliferation" EXACT [] synonym: "upregulation of mesenchymal cell proliferation" EXACT [] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0010464 ! regulation of mesenchymal cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0010463 ! mesenchymal cell proliferation relationship: positively_regulates GO:0010463 ! mesenchymal cell proliferation [Term] id: GO:0002062 name: chondrocyte differentiation namespace: biological_process def: "The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte. A chondrocyte is a polymorphic cell that forms cartilage." [GOC:dph] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000138 ! chondrocyte relationship: part_of GO:0051216 ! cartilage development relationship: results_in_acquisition_of_features_of CL:0000138 ! chondrocyte [Term] id: GO:0002063 name: chondrocyte development namespace: biological_process def: "The process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate." [GOC:dph] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000138 ! chondrocyte relationship: part_of GO:0002062 ! chondrocyte differentiation relationship: results_in_development_of CL:0000138 ! chondrocyte [Term] id: GO:0002064 name: epithelial cell development namespace: biological_process def: "The process whose specific outcome is the progression of an epithelial cell over time, from its formation to the mature structure. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface." [GOC:dph] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000066 ! epithelial cell relationship: part_of GO:0030855 ! epithelial cell differentiation relationship: results_in_development_of CL:0000066 ! epithelial cell [Term] id: GO:0002065 name: columnar/cuboidal epithelial cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube." [GOC:dph] is_a: GO:0030855 ! epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000075 ! columnar/cuboidal epithelial cell relationship: results_in_acquisition_of_features_of CL:0000075 ! columnar/cuboidal epithelial cell [Term] id: GO:0002066 name: columnar/cuboidal epithelial cell development namespace: biological_process def: "The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell over time, from its formation to the mature structure. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube." [GOC:dph] is_a: GO:0002064 ! epithelial cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000075 ! columnar/cuboidal epithelial cell relationship: part_of GO:0002065 ! columnar/cuboidal epithelial cell differentiation relationship: results_in_development_of CL:0000075 ! columnar/cuboidal epithelial cell [Term] id: GO:0002067 name: glandular epithelial cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a glandular epithelial cell. A glandular epithelial cell is a columnar/cuboidal epithelial cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland." [GOC:dph] is_a: GO:0002065 ! columnar/cuboidal epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000150 ! glandular epithelial cell relationship: results_in_acquisition_of_features_of CL:0000150 ! glandular epithelial cell [Term] id: GO:0002068 name: glandular epithelial cell development namespace: biological_process def: "The process whose specific outcome is the progression of a glandular epithelial cell over time, from its formation to the mature structure. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland." [GOC:dph] is_a: GO:0002066 ! columnar/cuboidal epithelial cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000150 ! glandular epithelial cell relationship: part_of GO:0002067 ! glandular epithelial cell differentiation relationship: results_in_development_of CL:0000150 ! glandular epithelial cell [Term] id: GO:0002069 name: columnar/cuboidal epithelial cell maturation namespace: biological_process def: "The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell to attain its fully functional state. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube." [GOC:dph] is_a: GO:0002070 ! epithelial cell maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of CL:0000075 ! columnar/cuboidal epithelial cell relationship: part_of GO:0002066 ! columnar/cuboidal epithelial cell development relationship: results_in_maturation_of CL:0000075 ! columnar/cuboidal epithelial cell [Term] id: GO:0002070 name: epithelial cell maturation namespace: biological_process def: "The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface." [GOC:dph] is_a: GO:0048469 ! cell maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of CL:0000066 ! epithelial cell relationship: part_of GO:0002064 ! epithelial cell development relationship: results_in_maturation_of CL:0000066 ! epithelial cell [Term] id: GO:0002071 name: glandular epithelial cell maturation namespace: biological_process def: "The developmental process, independent of morphogenetic (shape) change, that is required for a glandular epithelial cell to attain its fully functional state. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland." [GOC:dph] is_a: GO:0002069 ! columnar/cuboidal epithelial cell maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of CL:0000150 ! glandular epithelial cell relationship: part_of GO:0002068 ! glandular epithelial cell development relationship: results_in_maturation_of CL:0000150 ! glandular epithelial cell [Term] id: GO:0002072 name: optic cup morphogenesis involved in camera-type eye development namespace: biological_process def: "The invagination of the optic vesicle to form two-walled indentations, the optic cups, that will go on to form the retina. This process begins with the optic vesicle becoming a two-walled structure and its subsequent shape changes. It does not include the fate commitment of cells to become the pigmented retina and the neural retina. An example of this process is found in Mus musculus." [GOC:dph, GOC:mtg_sensu, GOC:sdb_2009, GOC:tb, ISBN:0878932437] synonym: "optic cup morphogenesis involved in camera-style eye development" EXACT [] is_a: GO:0016331 ! morphogenesis of embryonic epithelium intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003072 ! optic cup relationship: part_of GO:0060900 ! embryonic camera-type eye formation relationship: results_in_morphogenesis_of UBERON:0003072 ! optic cup [Term] id: GO:0002080 name: acrosomal membrane namespace: cellular_component def: "The membrane that surrounds the acrosomal lumen. The acrosome is a special type of lysosome in the head of a spermatozoon that contains acid hydrolases and is concerned with the breakdown of the outer membrane of the ovum during fertilization." [GOC:dph] is_a: GO:0030667 ! secretory granule membrane intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0001669 ! acrosomal vesicle relationship: bounding_layer_of GO:0001669 ! acrosomal vesicle relationship: part_of GO:0001669 ! acrosomal vesicle [Term] id: GO:0002085 name: inhibition of neuroepithelial cell differentiation namespace: biological_process def: "Any process that prevents the activation of neuroepithelial cell differentiation. Neuroepithelial cell differentiation is the process in which epiblast cells acquire specialized features of neuroepithelial cells." [GOC:dph, PMID:16678814] synonym: "negative regulation of neural plate formation" NARROW [GOC:dph, GOC:tb] synonym: "repression of premature neural plate formation" NARROW [GOC:dph, GOC:tb] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis is_a: GO:0030857 ! negative regulation of epithelial cell differentiation is_a: GO:0045995 ! regulation of embryonic development is_a: GO:0048505 ! regulation of timing of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060563 ! neuroepithelial cell differentiation relationship: negatively_regulates GO:0060563 ! neuroepithelial cell differentiation [Term] id: GO:0002087 name: regulation of respiratory gaseous exchange by nervous system process namespace: biological_process def: "A process carried out by the nervous system that is required for the proper control of respiratory gaseous exchange. This process occurs in the respiratory center of the brain in vertebrates." [GOC:dph, GOC:tb, PMID:12458206] synonym: "neurological control of breathing" EXACT [GOC:dph, GOC:tb] synonym: "regulation of respiratory gaseous exchange by neurological system process" EXACT [] is_a: GO:0044065 ! regulation of respiratory system process is_a: GO:0050877 ! nervous system process intersection_of: GO:0050877 ! nervous system process intersection_of: regulates GO:0007585 ! respiratory gaseous exchange by respiratory system [Term] id: GO:0002088 name: lens development in camera-type eye namespace: biological_process def: "The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus." [GOC:dph, ISBN:0582064333] synonym: "lens development" EXACT [] synonym: "lens development in camera-style eye" EXACT [] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000965 ! lens of camera-type eye relationship: part_of GO:0043010 ! camera-type eye development relationship: results_in_development_of UBERON:0000965 ! lens of camera-type eye [Term] id: GO:0002089 name: lens morphogenesis in camera-type eye namespace: biological_process def: "The process in which the anatomical structures of the lens are generated and organized. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus." [GOC:dph, GOC:mtg_sensu] synonym: "lens morphogenesis" EXACT [] synonym: "lens morphogenesis in camera-style eye" EXACT [] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000965 ! lens of camera-type eye relationship: part_of GO:0002088 ! lens development in camera-type eye relationship: part_of GO:0048593 ! camera-type eye morphogenesis relationship: results_in_morphogenesis_of UBERON:0000965 ! lens of camera-type eye [Term] id: GO:0002119 name: nematode larval development namespace: biological_process def: "The process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew." [GOC:ems, GOC:kmv] is_a: GO:0002164 ! larval development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0009850 ! nematode larva relationship: in_taxon NCBITaxon:33213 {all_only="true"} ! Bilateria relationship: only_in_taxon NCBITaxon:33213 ! Bilateria relationship: results_in_development_of UBERON:0009850 ! nematode larva [Term] id: GO:0002164 name: larval development namespace: biological_process def: "The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. The larva is the early, immature form of an that at birth or hatching is fundamentally unlike its parent and must metamorphose before assuming the adult characters." [GOC:jid, ISBN:0877795088] is_a: GO:0007275 ! multicellular organism development is_a: GO:0009791 ! post-embryonic development [Term] id: GO:0002176 name: male germ cell proliferation namespace: biological_process def: "The multiplication or reproduction of male germ cells, resulting in the expansion of a cell population." [GOC:hjd] is_a: GO:0036093 ! germ cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000015 ! male germ cell relationship: acts_on_population_of CL:0000015 ! male germ cell created_by: hjd creation_date: 2010-11-18T02:35:14Z [Term] id: GO:0002213 name: defense response to insect namespace: biological_process alt_id: GO:0002214 def: "A response to protect an organism from a directly detected or perceived external threat from an insect or insects to that organism." [GOC:add] synonym: "physiological defense response to insect" EXACT [] is_a: GO:0006952 ! defense response intersection_of: GO:0006952 ! defense response intersection_of: has_primary_input NCBITaxon:50557 ! Insecta relationship: has_primary_input NCBITaxon:50557 ! Insecta [Term] id: GO:0002215 name: defense response to nematode namespace: biological_process alt_id: GO:0002216 def: "A response to protect an organism from a directly detected or perceived external threat from a nematode or nematodes, which results in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack." [GOC:add, PMID:11516579, PMID:14506883] synonym: "physiological defense response to nematode" EXACT [] is_a: GO:0006952 ! defense response intersection_of: GO:0006952 ! defense response intersection_of: has_primary_input NCBITaxon:6231 ! Nematoda relationship: has_primary_input NCBITaxon:6231 ! Nematoda [Term] id: GO:0002244 name: hematopoietic progenitor cell differentiation namespace: biological_process def: "The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells." [GOC:add, GOC:rl, ISBN:0781735149, PMID:16551251] synonym: "haematopoietic progenitor cell differentiation" EXACT [] synonym: "haemopoietic progenitor cell differentiation" EXACT [] synonym: "hemopoietic progenitor cell differentiation" EXACT [] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0008001 ! hematopoietic precursor cell relationship: part_of GO:0030097 ! hemopoiesis relationship: results_in_acquisition_of_features_of CL:0008001 ! hematopoietic precursor cell [Term] id: GO:0002250 name: adaptive immune response namespace: biological_process def: "An immune response mediated by cells expressing specific receptors for antigens produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory)." [GO_REF:0000022, GOC:add, ISBN:0781735149] synonym: "acquired immune response" EXACT [ISBN:068340007X] synonym: "immune memory response" EXACT [GOC:add] xref: Wikipedia:Adaptive_immune_system is_a: GO:0006955 ! immune response relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa [Term] id: GO:0002251 name: organ or tissue specific immune response namespace: biological_process def: "An immune response taking place in an organ or tissues such as the liver, brain, mucosa, or nervous system tissues." [GO_REF:0000022, GOC:jal] synonym: "immune response in organ or tissue" EXACT [] is_a: GO:0006955 ! immune response [Term] id: GO:0002252 name: immune effector process namespace: biological_process def: "Any process of the immune system that executes a component of an immune response. An effector immune process takes place after its activation." [GO_REF:0000022, GOC:add, ISBN:0781735149] is_a: GO:0002376 ! immune system process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/18737" xsd:anyURI [Term] id: GO:0002260 name: lymphocyte homeostasis namespace: biological_process def: "The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus." [GOC:add, PMID:15826826, PMID:16319493, PMID:16551252, PMID:16551262] is_a: GO:0001776 ! leukocyte homeostasis intersection_of: GO:0048872 ! homeostasis of number of cells intersection_of: acts_on_population_of CL:0000542 ! lymphocyte relationship: acts_on_population_of CL:0000542 ! lymphocyte [Term] id: GO:0002262 name: myeloid cell homeostasis namespace: biological_process def: "The process of regulating the proliferation and elimination of myeloid cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus." [CL:0000763, GOC:add] is_a: GO:0002376 ! immune system process is_a: GO:0048872 ! homeostasis of number of cells intersection_of: GO:0048872 ! homeostasis of number of cells intersection_of: acts_on_population_of CL:0000763 ! myeloid cell relationship: acts_on_population_of CL:0000763 ! myeloid cell [Term] id: GO:0002263 name: cell activation involved in immune response namespace: biological_process def: "A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response." [GO_REF:0000022, GOC:add, ISBN:0781735149] synonym: "cell activation during immune response" RELATED [GOC:tb] is_a: GO:0001775 ! cell activation is_a: GO:0002252 ! immune effector process intersection_of: GO:0001775 ! cell activation intersection_of: part_of GO:0006955 ! immune response relationship: part_of GO:0006955 ! immune response [Term] id: GO:0002264 name: endothelial cell activation involved in immune response namespace: biological_process def: "A change in the morphology or behavior of an endothelial cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response." [GOC:add, ISBN:0781735149] synonym: "endothelial cell activation during immune response" RELATED [GOC:tb] is_a: GO:0002263 ! cell activation involved in immune response is_a: GO:0042118 ! endothelial cell activation intersection_of: GO:0042118 ! endothelial cell activation intersection_of: part_of GO:0006955 ! immune response [Term] id: GO:0002269 name: leukocyte activation involved in inflammatory response namespace: biological_process def: "A change in the morphology or behavior of a leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an inflammatory response." [GOC:add, ISBN:0781735149] synonym: "immune cell activation during inflammatory response" RELATED [] synonym: "leukocyte activation during inflammatory response" RELATED [GOC:tb] is_a: GO:0045321 ! leukocyte activation intersection_of: GO:0045321 ! leukocyte activation intersection_of: part_of GO:0006954 ! inflammatory response relationship: part_of GO:0006954 ! inflammatory response [Term] id: GO:0002274 name: myeloid leukocyte activation namespace: biological_process def: "A change in the morphology or behavior of a myeloid leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand." [GOC:add, ISBN:0781735149] synonym: "myeloid leucocyte activation" EXACT [] is_a: GO:0045321 ! leukocyte activation intersection_of: GO:0001775 ! cell activation intersection_of: has_primary_input CL:0000766 ! myeloid leukocyte relationship: has_primary_input CL:0000766 ! myeloid leukocyte [Term] id: GO:0002285 name: lymphocyte activation involved in immune response namespace: biological_process def: "A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response." [GOC:add, ISBN:0781735149] synonym: "lymphocyte activation during immune response" RELATED [GOC:tb] is_a: GO:0002366 ! leukocyte activation involved in immune response is_a: GO:0046649 ! lymphocyte activation intersection_of: GO:0046649 ! lymphocyte activation intersection_of: part_of GO:0006955 ! immune response [Term] id: GO:0002286 name: T cell activation involved in immune response namespace: biological_process def: "The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response." [GOC:add, ISBN:0781735149] synonym: "T cell activation during immune response" RELATED [GOC:tb] synonym: "T lymphocyte activation during immune response" RELATED [] synonym: "T-cell activation during immune response" RELATED [] synonym: "T-lymphocyte activation during immune response" RELATED [] is_a: GO:0002285 ! lymphocyte activation involved in immune response is_a: GO:0042110 ! T cell activation intersection_of: GO:0042110 ! T cell activation intersection_of: part_of GO:0006955 ! immune response [Term] id: GO:0002292 name: T cell differentiation involved in immune response namespace: biological_process def: "The process in which an antigenically naive T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells." [GOC:add, ISBN:0781735149] comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. synonym: "T cell development involved in immune response" RELATED [GOC:add] synonym: "T cell differentiation during immune response" RELATED [GOC:tb] synonym: "T lymphocyte differentiation during immune response" RELATED [] synonym: "T-cell differentiation during immune response" RELATED [] synonym: "T-lymphocyte differentiation during immune response" RELATED [] is_a: GO:0002286 ! T cell activation involved in immune response is_a: GO:0030217 ! T cell differentiation intersection_of: GO:0030217 ! T cell differentiation intersection_of: part_of GO:0006955 ! immune response [Term] id: GO:0002309 name: T cell proliferation involved in immune response namespace: biological_process def: "The expansion of a T cell population by cell division as part of an immune response." [GOC:add, ISBN:0781735149] synonym: "T cell proliferation during immune response" RELATED [GOC:tb] synonym: "T lymphocyte proliferation during immune response" RELATED [] synonym: "T-cell proliferation during immune response" RELATED [] synonym: "T-lymphocyte proliferation during immune response" RELATED [] is_a: GO:0002286 ! T cell activation involved in immune response is_a: GO:0042098 ! T cell proliferation intersection_of: GO:0042098 ! T cell proliferation intersection_of: part_of GO:0006955 ! immune response [Term] id: GO:0002318 name: myeloid progenitor cell differentiation namespace: biological_process def: "The process in which a precursor cell type acquires the specialized features of a myeloid progenitor cell. Myeloid progenitor cells include progenitor cells for any of the myeloid lineages." [GOC:add, PMID:16551264] is_a: GO:0002244 ! hematopoietic progenitor cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000839 ! myeloid lineage restricted progenitor cell relationship: results_in_acquisition_of_features_of CL:0000839 ! myeloid lineage restricted progenitor cell [Term] id: GO:0002320 name: lymphoid progenitor cell differentiation namespace: biological_process def: "The process in which a precursor cell type acquires the specialized features of a lymphoid progenitor cell. Lymphoid progenitor cells include progenitor cells for any of the lymphoid lineages." [GOC:add, PMID:16551251, PMID:16551264] is_a: GO:0002244 ! hematopoietic progenitor cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000838 ! lymphoid lineage restricted progenitor cell relationship: results_in_acquisition_of_features_of CL:0000838 ! lymphoid lineage restricted progenitor cell [Term] id: GO:0002351 name: serotonin production involved in inflammatory response namespace: biological_process def: "The synthesis or release of serotonin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels." [GOC:add, ISBN:0781735149, PMID:16730260] synonym: "serotonin production involved in acute inflammatory response" BROAD [] is_a: GO:0002532 ! production of molecular mediator involved in inflammatory response [Term] id: GO:0002366 name: leukocyte activation involved in immune response namespace: biological_process def: "A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response." [GOC:add, ISBN:0781735149] synonym: "immune cell activation during immune response" RELATED [] synonym: "leucocyte activation during immune response" RELATED [] synonym: "leukocyte activation during immune response" RELATED [GOC:tb] is_a: GO:0002263 ! cell activation involved in immune response is_a: GO:0045321 ! leukocyte activation intersection_of: GO:0045321 ! leukocyte activation intersection_of: part_of GO:0006955 ! immune response [Term] id: GO:0002367 name: cytokine production involved in immune response namespace: biological_process alt_id: GO:0002374 alt_id: GO:0002375 def: "The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus contributing to an immune response, resulting in an increase in its intracellular or extracellular levels." [GO_REF:0000022, GOC:add, ISBN:0781735149] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms. subset: gocheck_do_not_annotate synonym: "cytokine biosynthetic process involved in immune response" NARROW [] synonym: "cytokine production during immune response" RELATED [GOC:dph] synonym: "cytokine secretion during immune response" RELATED [GOC:dph] synonym: "cytokine secretion involved in immune response" RELATED [] is_a: GO:0001816 ! cytokine production is_a: GO:0002440 ! production of molecular mediator of immune response intersection_of: GO:0001816 ! cytokine production intersection_of: part_of GO:0006955 ! immune response relationship: part_of GO:0006955 ! immune response [Term] id: GO:0002369 name: T cell cytokine production namespace: biological_process def: "Any process that contributes to cytokine production by a T cell." [GOC:add, ISBN:0781735149] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms. subset: gocheck_do_not_annotate synonym: "T lymphocyte cytokine production" EXACT [] synonym: "T-cell cytokine production" EXACT [] synonym: "T-lymphocyte cytokine production" EXACT [] is_a: GO:0002367 ! cytokine production involved in immune response is_a: GO:0002456 ! T cell mediated immunity intersection_of: GO:0001816 ! cytokine production intersection_of: process_has_causal_agent CL:0000084 ! T cell [Term] id: GO:0002371 name: dendritic cell cytokine production namespace: biological_process def: "Any process that contributes to cytokine production by a dendritic cell." [GOC:add, ISBN:0781735149] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms. subset: gocheck_do_not_annotate is_a: GO:0002367 ! cytokine production involved in immune response is_a: GO:0002443 ! leukocyte mediated immunity intersection_of: GO:0001816 ! cytokine production intersection_of: process_has_causal_agent CL:0000451 ! dendritic cell relationship: process_has_causal_agent CL:0000451 ! dendritic cell [Term] id: GO:0002376 name: immune system process namespace: biological_process def: "Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats." [GO_REF:0000022, GOC:add] comment: Note that this term is a direct child of 'biological_process ; GO:0008150' because some immune system processes are types of cellular process (GO:0009987), whereas others are types of multicellular organism process (GO:0032501). subset: goslim_agr subset: goslim_chembl subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_mouse subset: goslim_pir xref: Wikipedia:Immune_system is_a: GO:0008150 ! biological process property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0002384 name: hepatic immune response namespace: biological_process def: "An immune response taking place in the liver." [GO_REF:0000022, GOC:jal, ISBN:0781735149] is_a: GO:0002251 ! organ or tissue specific immune response intersection_of: GO:0006955 ! immune response intersection_of: occurs_in UBERON:0002107 ! liver relationship: in_taxon NCBITaxon:7742 {all_only="true"} ! Vertebrata relationship: occurs_in UBERON:0002107 ! liver relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata [Term] id: GO:0002396 name: MHC protein complex assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form an MHC protein complex." [GOC:add, ISBN:0781735149, PMID:15771591, PMID:15928678] is_a: GO:0065003 ! protein-containing complex assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0042611 ! MHC protein complex relationship: results_in_assembly_of GO:0042611 ! MHC protein complex [Term] id: GO:0002399 name: MHC class II protein complex assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form an MHC class II protein complex." [GOC:add, ISBN:0781735149, PMID:15771591] is_a: GO:0002396 ! MHC protein complex assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0042613 ! MHC class II protein complex relationship: results_in_assembly_of GO:0042613 ! MHC class II protein complex [Term] id: GO:0002440 name: production of molecular mediator of immune response namespace: biological_process def: "The synthesis or release of any molecular mediator of the immune response, resulting in an increase in its intracellular or extracellular levels." [GO_REF:0000022, GOC:add, ISBN:0781735149] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms. subset: gocheck_do_not_annotate synonym: "production of cellular mediator of immune response" RELATED [] is_a: GO:0002376 ! immune system process is_a: GO:0010467 ! gene expression [Term] id: GO:0002442 name: serotonin secretion involved in inflammatory response namespace: biological_process def: "The regulated release of serotonin by a cell as part of an inflammatory response." [GOC:add, ISBN:0781735149] synonym: "serotonin release involved in inflammatory response" RELATED [GOC:tb] synonym: "serotonin secretion involved in acute inflammatory response" BROAD [] is_a: GO:0001820 ! serotonin secretion intersection_of: GO:0001820 ! serotonin secretion intersection_of: part_of GO:0006954 ! inflammatory response relationship: part_of GO:0002351 ! serotonin production involved in inflammatory response [Term] id: GO:0002443 name: leukocyte mediated immunity namespace: biological_process alt_id: GO:0019723 alt_id: GO:0042087 def: "Any process involved in the carrying out of an immune response by a leukocyte." [GO_REF:0000022, GOC:add, ISBN:0781735149] synonym: "cell-mediated immune response" RELATED [] synonym: "cellular immune response" RELATED [] synonym: "immune cell effector process" EXACT [] synonym: "immune cell mediated immunity" EXACT [] synonym: "leucocyte immune effector process" EXACT [] synonym: "leucocyte mediated immunity" EXACT [] synonym: "leukocyte immune effector process" EXACT [] is_a: GO:0002252 ! immune effector process intersection_of: GO:0002376 ! immune system process intersection_of: process_has_causal_agent CL:0000738 ! leukocyte relationship: in_taxon NCBITaxon:7742 {all_only="true"} ! Vertebrata relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: process_has_causal_agent CL:0000738 ! leukocyte [Term] id: GO:0002444 name: myeloid leukocyte mediated immunity namespace: biological_process def: "Any process involved in the carrying out of an immune response by a myeloid leukocyte." [GO_REF:0000022, GOC:add, ISBN:0781735149] synonym: "myeloid leucocyte immune effector process" EXACT [] synonym: "myeloid leucocyte mediated immunity" EXACT [] synonym: "myeloid leukocyte immune effector process" EXACT [] is_a: GO:0002443 ! leukocyte mediated immunity intersection_of: GO:0002376 ! immune system process intersection_of: process_has_causal_agent CL:0000766 ! myeloid leukocyte relationship: process_has_causal_agent CL:0000766 ! myeloid leukocyte [Term] id: GO:0002449 name: lymphocyte mediated immunity namespace: biological_process def: "Any process involved in the carrying out of an immune response by a lymphocyte." [GO_REF:0000022, GOC:add, ISBN:0781735149] synonym: "cell-mediated immunity" BROAD [] synonym: "cellular immune response" BROAD [] is_a: GO:0002443 ! leukocyte mediated immunity intersection_of: GO:0002376 ! immune system process intersection_of: process_has_causal_agent CL:0000542 ! lymphocyte relationship: process_has_causal_agent CL:0000542 ! lymphocyte [Term] id: GO:0002456 name: T cell mediated immunity namespace: biological_process def: "Any process involved in the carrying out of an immune response by a T cell." [GO_REF:0000022, GOC:add, ISBN:0781735149] synonym: "cell-mediated immunity" BROAD [] synonym: "cellular immune response" BROAD [] synonym: "T lymphocyte mediated immunity" EXACT [] synonym: "T-cell mediated immunity" EXACT [] synonym: "T-lymphocyte mediated immunity" EXACT [] is_a: GO:0002449 ! lymphocyte mediated immunity is_a: GO:0002460 ! adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains intersection_of: GO:0002376 ! immune system process intersection_of: process_has_causal_agent CL:0000084 ! T cell relationship: process_has_causal_agent CL:0000084 ! T cell [Term] id: GO:0002457 name: T cell antigen processing and presentation namespace: biological_process def: "The process in which a T cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex." [GOC:add, PMID:11417857, PMID:15120183] synonym: "T lymphocyte antigen processing and presentation" EXACT [] synonym: "T-cell antigen processing and presentation" EXACT [] synonym: "T-lymphocyte antigen processing and presentation" EXACT [] is_a: GO:0019882 ! antigen processing and presentation intersection_of: GO:0019882 ! antigen processing and presentation intersection_of: occurs_in CL:0000084 ! T cell relationship: occurs_in CL:0000084 ! T cell relationship: part_of GO:0002456 ! T cell mediated immunity [Term] id: GO:0002460 name: adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains namespace: biological_process def: "An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains. Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies) produced by B cells. The first encounter with antigen elicits a primary immune response that is slow and not of great magnitude. T and B cells selected by antigen become activated and undergo clonal expansion. A fraction of antigen-reactive T and B cells become memory cells, whereas others differentiate into effector cells. The memory cells generated during the primary response enable a much faster and stronger secondary immune response upon subsequent exposures to the same antigen (immunological memory). An example of this is the adaptive immune response found in Mus musculus." [GOC:add, GOC:mtg_sensu, ISBN:0781735149, ISBN:1405196831] is_a: GO:0002250 ! adaptive immune response [Term] id: GO:0002468 name: dendritic cell antigen processing and presentation namespace: biological_process def: "The process in which a dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex." [GOC:add, ISBN:0781735149, PMID:15771591] is_a: GO:0019882 ! antigen processing and presentation intersection_of: GO:0019882 ! antigen processing and presentation intersection_of: occurs_in CL:0000451 ! dendritic cell relationship: occurs_in CL:0000451 ! dendritic cell [Term] id: GO:0002504 name: antigen processing and presentation of peptide or polysaccharide antigen via MHC class II namespace: biological_process def: "The process in which an antigen-presenting cell expresses antigen (peptide or polysaccharide) on its cell surface in association with an MHC class II protein complex." [GOC:add, ISBN:0781735149, PMID:15531770, PMID:15771591, PMID:16153240] synonym: "peptide or polysaccharide antigen processing and presentation of via MHC class II" EXACT [] is_a: GO:0019882 ! antigen processing and presentation [Term] id: GO:0002520 name: immune system development namespace: biological_process def: "The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process." [GOC:add, GOC:dph] subset: goslim_drosophila is_a: GO:0002376 ! immune system process is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002405 ! immune system relationship: results_in_development_of UBERON:0002405 ! immune system [Term] id: GO:0002521 name: leukocyte differentiation namespace: biological_process def: "The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a leukocyte. A leukocyte is an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue." [CL:0000738, GOC:add, PMID:16551264] synonym: "immune cell differentiation" EXACT [] synonym: "leucocyte differentiation" EXACT [] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000738 ! leukocyte relationship: part_of GO:0030097 ! hemopoiesis relationship: results_in_acquisition_of_features_of CL:0000738 ! leukocyte [Term] id: GO:0002522 name: leukocyte migration involved in immune response namespace: biological_process def: "The movement of a leukocyte within or between different tissues and organs of the body as part of an immune response." [GOC:add, ISBN:0781735149, PMID:14680625, PMID:14708592, PMID:7507411, PMID:8600538] synonym: "immune cell migration during immune response" EXACT [] synonym: "immune cell trafficking during immune response" EXACT [] synonym: "leucocyte migration during immune response" EXACT [] synonym: "leucocyte trafficking during immune response" EXACT [] synonym: "leukocyte trafficking during immune response" EXACT [] is_a: GO:0002252 ! immune effector process is_a: GO:0050900 ! leukocyte migration intersection_of: GO:0050900 ! leukocyte migration intersection_of: part_of GO:0006955 ! immune response relationship: part_of GO:0006955 ! immune response [Term] id: GO:0002523 name: leukocyte migration involved in inflammatory response namespace: biological_process def: "The movement of a leukocyte within or between different tissues and organs of the body contributing to an inflammatory response." [GOC:add, ISBN:0781735149, PMID:14680625, PMID:14708592, PMID:7507411, PMID:8600538] synonym: "immune cell migration during inflammatory response" RELATED [] synonym: "immune cell trafficking during inflammatory response" RELATED [] synonym: "leucocyte migration during inflammatory response" RELATED [] synonym: "leucocyte trafficking during inflammatory response" RELATED [] synonym: "leukocyte migration during inflammatory response" RELATED [GOC:dph] synonym: "leukocyte trafficking during inflammatory response" RELATED [] is_a: GO:0050900 ! leukocyte migration intersection_of: GO:0050900 ! leukocyte migration intersection_of: part_of GO:0006954 ! inflammatory response relationship: part_of GO:0006954 ! inflammatory response [Term] id: GO:0002532 name: production of molecular mediator involved in inflammatory response namespace: biological_process def: "The synthesis or release of any molecular mediator of the inflammatory response following an inflammatory stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:add, GOC:dph, GOC:tb, ISBN:0781735149] synonym: "production of cellular mediator of acute inflammation" RELATED [] synonym: "production of molecular mediator involved in acute inflammatory response" BROAD [] is_a: GO:0032501 ! multicellular organismal process relationship: part_of GO:0006954 ! inflammatory response [Term] id: GO:0002534 name: cytokine production involved in inflammatory response namespace: biological_process def: "The synthesis or release of a cytokine following a inflammatory stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels." [GOC:add, ISBN:0781735149] subset: gocheck_do_not_annotate synonym: "cytokine production involved in acute inflammatory response" BROAD [] is_a: GO:0001816 ! cytokine production is_a: GO:0002532 ! production of molecular mediator involved in inflammatory response intersection_of: GO:0001816 ! cytokine production intersection_of: part_of GO:0006954 ! inflammatory response [Term] id: GO:0002572 name: pro-T cell differentiation namespace: biological_process def: "The process in which a precursor cell type acquires the specialized features of a pro-T cell. Pro-T cells are the earliest stage of the T cell lineage but are not fully committed." [GOC:add, ISBN:0781735149] synonym: "pro-T lymphocyte differentiation" EXACT [] is_a: GO:0002320 ! lymphoid progenitor cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000827 ! pro-T cell relationship: part_of GO:0030217 ! T cell differentiation relationship: results_in_acquisition_of_features_of CL:0000827 ! pro-T cell [Term] id: GO:0002573 name: myeloid leukocyte differentiation namespace: biological_process def: "The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte lineage." [GOC:add, PMID:16551251] synonym: "myeloid leucocyte differentiation" EXACT [] is_a: GO:0002521 ! leukocyte differentiation is_a: GO:0030099 ! myeloid cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000766 ! myeloid leukocyte relationship: results_in_acquisition_of_features_of CL:0000766 ! myeloid leukocyte [Term] id: GO:0002577 name: regulation of antigen processing and presentation namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of antigen processing and presentation." [GOC:add] is_a: GO:0002682 ! regulation of immune system process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0019882 ! antigen processing and presentation relationship: regulates GO:0019882 ! antigen processing and presentation [Term] id: GO:0002578 name: negative regulation of antigen processing and presentation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation." [GOC:add] synonym: "down regulation of antigen processing and presentation" EXACT [] synonym: "down-regulation of antigen processing and presentation" EXACT [] synonym: "downregulation of antigen processing and presentation" EXACT [] synonym: "inhibition of antigen processing and presentation" NARROW [] is_a: GO:0002577 ! regulation of antigen processing and presentation is_a: GO:0002683 ! negative regulation of immune system process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0019882 ! antigen processing and presentation relationship: negatively_regulates GO:0019882 ! antigen processing and presentation [Term] id: GO:0002579 name: positive regulation of antigen processing and presentation namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation." [GOC:add] synonym: "activation of antigen processing and presentation" NARROW [] synonym: "stimulation of antigen processing and presentation" NARROW [] synonym: "up regulation of antigen processing and presentation" EXACT [] synonym: "up-regulation of antigen processing and presentation" EXACT [] synonym: "upregulation of antigen processing and presentation" EXACT [] is_a: GO:0002577 ! regulation of antigen processing and presentation is_a: GO:0002684 ! positive regulation of immune system process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0019882 ! antigen processing and presentation relationship: positively_regulates GO:0019882 ! antigen processing and presentation [Term] id: GO:0002580 name: regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II." [GOC:add] synonym: "regulation of peptide or polysaccharide antigen processing and presentation via MHC class II" EXACT [] is_a: GO:0002577 ! regulation of antigen processing and presentation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002504 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II relationship: regulates GO:0002504 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [Term] id: GO:0002581 name: negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II." [GOC:add] synonym: "down regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" EXACT [] synonym: "down-regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" EXACT [] synonym: "downregulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" EXACT [] synonym: "inhibition of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" NARROW [] synonym: "negative regulation of peptide or polysaccharide antigen processing and presentation via MHC class II" EXACT [] is_a: GO:0002578 ! negative regulation of antigen processing and presentation is_a: GO:0002580 ! regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002504 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II relationship: negatively_regulates GO:0002504 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [Term] id: GO:0002582 name: positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II." [GOC:add] synonym: "activation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" NARROW [] synonym: "positive regulation of peptide or polysaccharide antigen processing and presentation via MHC class II" EXACT [] synonym: "stimulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" NARROW [] synonym: "up regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" EXACT [] synonym: "up-regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" EXACT [] synonym: "upregulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" EXACT [] is_a: GO:0002579 ! positive regulation of antigen processing and presentation is_a: GO:0002580 ! regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002504 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II relationship: positively_regulates GO:0002504 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [Term] id: GO:0002604 name: regulation of dendritic cell antigen processing and presentation namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of dendritic cell antigen processing and presentation." [GOC:add] is_a: GO:0002577 ! regulation of antigen processing and presentation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002468 ! dendritic cell antigen processing and presentation relationship: regulates GO:0002468 ! dendritic cell antigen processing and presentation [Term] id: GO:0002605 name: negative regulation of dendritic cell antigen processing and presentation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell antigen processing and presentation." [GOC:add] synonym: "down regulation of dendritic cell antigen processing and presentation" EXACT [] synonym: "down-regulation of dendritic cell antigen processing and presentation" EXACT [] synonym: "downregulation of dendritic cell antigen processing and presentation" EXACT [] synonym: "inhibition of dendritic cell antigen processing and presentation" NARROW [] is_a: GO:0002578 ! negative regulation of antigen processing and presentation is_a: GO:0002604 ! regulation of dendritic cell antigen processing and presentation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002468 ! dendritic cell antigen processing and presentation relationship: negatively_regulates GO:0002468 ! dendritic cell antigen processing and presentation [Term] id: GO:0002606 name: positive regulation of dendritic cell antigen processing and presentation namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of dendritic cell antigen processing and presentation." [GOC:add] synonym: "activation of dendritic cell antigen processing and presentation" NARROW [] synonym: "stimulation of dendritic cell antigen processing and presentation" NARROW [] synonym: "up regulation of dendritic cell antigen processing and presentation" EXACT [] synonym: "up-regulation of dendritic cell antigen processing and presentation" EXACT [] synonym: "upregulation of dendritic cell antigen processing and presentation" EXACT [] is_a: GO:0002579 ! positive regulation of antigen processing and presentation is_a: GO:0002604 ! regulation of dendritic cell antigen processing and presentation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002468 ! dendritic cell antigen processing and presentation relationship: positively_regulates GO:0002468 ! dendritic cell antigen processing and presentation [Term] id: GO:0002625 name: regulation of T cell antigen processing and presentation namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of T cell antigen processing and presentation." [GOC:add] synonym: "regulation of T lymphocyte antigen processing and presentation" EXACT [] synonym: "regulation of T-cell antigen processing and presentation" EXACT [] synonym: "regulation of T-lymphocyte antigen processing and presentation" EXACT [] is_a: GO:0002577 ! regulation of antigen processing and presentation is_a: GO:0002709 ! regulation of T cell mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002457 ! T cell antigen processing and presentation relationship: regulates GO:0002457 ! T cell antigen processing and presentation [Term] id: GO:0002626 name: negative regulation of T cell antigen processing and presentation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell antigen processing and presentation." [GOC:add] synonym: "down regulation of T cell antigen processing and presentation" EXACT [] synonym: "down-regulation of T cell antigen processing and presentation" EXACT [] synonym: "downregulation of T cell antigen processing and presentation" EXACT [] synonym: "inhibition of T cell antigen processing and presentation" NARROW [] synonym: "negative regulation of T lymphocyte antigen processing and presentation" EXACT [] synonym: "negative regulation of T-cell antigen processing and presentation" EXACT [] synonym: "negative regulation of T-lymphocyte antigen processing and presentation" EXACT [] is_a: GO:0002578 ! negative regulation of antigen processing and presentation is_a: GO:0002625 ! regulation of T cell antigen processing and presentation is_a: GO:0002710 ! negative regulation of T cell mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002457 ! T cell antigen processing and presentation relationship: negatively_regulates GO:0002457 ! T cell antigen processing and presentation [Term] id: GO:0002627 name: positive regulation of T cell antigen processing and presentation namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of T cell antigen processing and presentation." [GOC:add] synonym: "activation of T cell antigen processing and presentation" NARROW [] synonym: "positive regulation of T lymphocyte antigen processing and presentation" EXACT [] synonym: "positive regulation of T-cell antigen processing and presentation" EXACT [] synonym: "positive regulation of T-lymphocyte antigen processing and presentation" EXACT [] synonym: "stimulation of T cell antigen processing and presentation" NARROW [] synonym: "up regulation of T cell antigen processing and presentation" EXACT [] synonym: "up-regulation of T cell antigen processing and presentation" EXACT [] synonym: "upregulation of T cell antigen processing and presentation" EXACT [] is_a: GO:0002579 ! positive regulation of antigen processing and presentation is_a: GO:0002625 ! regulation of T cell antigen processing and presentation is_a: GO:0002711 ! positive regulation of T cell mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002457 ! T cell antigen processing and presentation relationship: positively_regulates GO:0002457 ! T cell antigen processing and presentation [Term] id: GO:0002682 name: regulation of immune system process namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of an immune system process." [GOC:add] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002376 ! immune system process relationship: regulates GO:0002376 ! immune system process [Term] id: GO:0002683 name: negative regulation of immune system process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process." [GOC:add] synonym: "down regulation of immune system process" EXACT [] synonym: "down-regulation of immune system process" EXACT [] synonym: "downregulation of immune system process" EXACT [] synonym: "inhibition of immune system process" NARROW [] is_a: GO:0002682 ! regulation of immune system process is_a: GO:0048519 ! negative regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002376 ! immune system process relationship: negatively_regulates GO:0002376 ! immune system process [Term] id: GO:0002684 name: positive regulation of immune system process namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of an immune system process." [GOC:add] synonym: "activation of immune system process" NARROW [] synonym: "stimulation of immune system process" NARROW [] synonym: "up regulation of immune system process" EXACT [] synonym: "up-regulation of immune system process" EXACT [] synonym: "upregulation of immune system process" EXACT [] is_a: GO:0002682 ! regulation of immune system process is_a: GO:0048518 ! positive regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002376 ! immune system process relationship: positively_regulates GO:0002376 ! immune system process [Term] id: GO:0002685 name: regulation of leukocyte migration namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of leukocyte migration." [GOC:add] synonym: "regulation of immune cell migration" EXACT [] synonym: "regulation of leucocyte migration" EXACT [] is_a: GO:0002682 ! regulation of immune system process is_a: GO:0030334 ! regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0050900 ! leukocyte migration relationship: regulates GO:0050900 ! leukocyte migration [Term] id: GO:0002686 name: negative regulation of leukocyte migration namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte migration." [GOC:add] synonym: "down regulation of leukocyte migration" EXACT [] synonym: "down-regulation of leukocyte migration" EXACT [] synonym: "downregulation of leukocyte migration" EXACT [] synonym: "inhibition of leukocyte migration" NARROW [] synonym: "negative regulation of immune cell migration" EXACT [] synonym: "negative regulation of leucocyte migration" EXACT [] is_a: GO:0002683 ! negative regulation of immune system process is_a: GO:0002685 ! regulation of leukocyte migration is_a: GO:0030336 ! negative regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0050900 ! leukocyte migration relationship: negatively_regulates GO:0050900 ! leukocyte migration [Term] id: GO:0002687 name: positive regulation of leukocyte migration namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of leukocyte migration." [GOC:add] synonym: "activation of leukocyte migration" NARROW [] synonym: "positive regulation of immune cell migration" EXACT [] synonym: "positive regulation of leucocyte migration" EXACT [] synonym: "stimulation of leukocyte migration" NARROW [] synonym: "up regulation of leukocyte migration" EXACT [] synonym: "up-regulation of leukocyte migration" EXACT [] synonym: "upregulation of leukocyte migration" EXACT [] is_a: GO:0002684 ! positive regulation of immune system process is_a: GO:0002685 ! regulation of leukocyte migration is_a: GO:0030335 ! positive regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0050900 ! leukocyte migration relationship: positively_regulates GO:0050900 ! leukocyte migration [Term] id: GO:0002694 name: regulation of leukocyte activation namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of leukocyte activation." [GOC:add] synonym: "regulation of immune cell activation" EXACT [] synonym: "regulation of leucocyte activation" EXACT [] is_a: GO:0002682 ! regulation of immune system process is_a: GO:0050865 ! regulation of cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0045321 ! leukocyte activation relationship: regulates GO:0045321 ! leukocyte activation [Term] id: GO:0002695 name: negative regulation of leukocyte activation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte activation." [GOC:add] synonym: "down regulation of leukocyte activation" EXACT [] synonym: "down-regulation of leukocyte activation" EXACT [] synonym: "downregulation of leukocyte activation" EXACT [] synonym: "inhibition of leukocyte activation" NARROW [] synonym: "negative regulation of immune cell activation" EXACT [] synonym: "negative regulation of leucocyte activation" EXACT [] is_a: GO:0002683 ! negative regulation of immune system process is_a: GO:0002694 ! regulation of leukocyte activation is_a: GO:0050866 ! negative regulation of cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0045321 ! leukocyte activation relationship: negatively_regulates GO:0045321 ! leukocyte activation [Term] id: GO:0002696 name: positive regulation of leukocyte activation namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of leukocyte activation." [GOC:add] synonym: "activation of leukocyte activation" NARROW [] synonym: "positive regulation of immune cell activation" EXACT [] synonym: "positive regulation of leucocyte activation" EXACT [] synonym: "stimulation of leukocyte activation" NARROW [] synonym: "up regulation of leukocyte activation" EXACT [] synonym: "up-regulation of leukocyte activation" EXACT [] synonym: "upregulation of leukocyte activation" EXACT [] is_a: GO:0002684 ! positive regulation of immune system process is_a: GO:0002694 ! regulation of leukocyte activation is_a: GO:0050867 ! positive regulation of cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0045321 ! leukocyte activation relationship: positively_regulates GO:0045321 ! leukocyte activation [Term] id: GO:0002697 name: regulation of immune effector process namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of an immune effector process." [GOC:add] is_a: GO:0002682 ! regulation of immune system process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002252 ! immune effector process relationship: regulates GO:0002252 ! immune effector process [Term] id: GO:0002698 name: negative regulation of immune effector process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune effector process." [GOC:add] synonym: "down regulation of immune effector process" EXACT [] synonym: "down-regulation of immune effector process" EXACT [] synonym: "downregulation of immune effector process" EXACT [] synonym: "inhibition of immune effector process" NARROW [] is_a: GO:0002683 ! negative regulation of immune system process is_a: GO:0002697 ! regulation of immune effector process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002252 ! immune effector process relationship: negatively_regulates GO:0002252 ! immune effector process [Term] id: GO:0002699 name: positive regulation of immune effector process namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of an immune effector process." [GOC:add] synonym: "activation of immune effector process" NARROW [] synonym: "stimulation of immune effector process" NARROW [] synonym: "up regulation of immune effector process" EXACT [] synonym: "up-regulation of immune effector process" EXACT [] synonym: "upregulation of immune effector process" EXACT [] is_a: GO:0002684 ! positive regulation of immune system process is_a: GO:0002697 ! regulation of immune effector process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002252 ! immune effector process relationship: positively_regulates GO:0002252 ! immune effector process [Term] id: GO:0002700 name: regulation of production of molecular mediator of immune response namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of the production of molecular mediator of immune response." [GOC:add] is_a: GO:0002697 ! regulation of immune effector process is_a: GO:0010468 ! regulation of gene expression intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002440 ! production of molecular mediator of immune response relationship: regulates GO:0002440 ! production of molecular mediator of immune response [Term] id: GO:0002701 name: negative regulation of production of molecular mediator of immune response namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of the production of molecular mediator of immune response." [GOC:add] synonym: "down regulation of production of molecular mediator of immune response" EXACT [] synonym: "down-regulation of production of molecular mediator of immune response" EXACT [] synonym: "downregulation of production of molecular mediator of immune response" EXACT [] synonym: "inhibition of production of molecular mediator of immune response" NARROW [] is_a: GO:0002698 ! negative regulation of immune effector process is_a: GO:0002700 ! regulation of production of molecular mediator of immune response is_a: GO:0010629 ! negative regulation of gene expression intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002440 ! production of molecular mediator of immune response relationship: negatively_regulates GO:0002440 ! production of molecular mediator of immune response [Term] id: GO:0002702 name: positive regulation of production of molecular mediator of immune response namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of the production of molecular mediator of immune response." [GOC:add] synonym: "activation of production of molecular mediator of immune response" NARROW [] synonym: "stimulation of production of molecular mediator of immune response" NARROW [] synonym: "up regulation of production of molecular mediator of immune response" EXACT [] synonym: "up-regulation of production of molecular mediator of immune response" EXACT [] synonym: "upregulation of production of molecular mediator of immune response" EXACT [] is_a: GO:0002699 ! positive regulation of immune effector process is_a: GO:0002700 ! regulation of production of molecular mediator of immune response is_a: GO:0010628 ! positive regulation of gene expression intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002440 ! production of molecular mediator of immune response relationship: positively_regulates GO:0002440 ! production of molecular mediator of immune response [Term] id: GO:0002703 name: regulation of leukocyte mediated immunity namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of leukocyte mediated immunity." [GOC:add] synonym: "regulation of immune cell mediated immunity" EXACT [] synonym: "regulation of leucocyte mediated immunity" EXACT [] is_a: GO:0002697 ! regulation of immune effector process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002443 ! leukocyte mediated immunity relationship: regulates GO:0002443 ! leukocyte mediated immunity [Term] id: GO:0002704 name: negative regulation of leukocyte mediated immunity namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte mediated immunity." [GOC:add] synonym: "down regulation of leukocyte mediated immunity" EXACT [] synonym: "down-regulation of leukocyte mediated immunity" EXACT [] synonym: "downregulation of leukocyte mediated immunity" EXACT [] synonym: "inhibition of leukocyte mediated immunity" NARROW [] synonym: "negative regulation of immune cell mediated immunity" EXACT [] synonym: "negative regulation of leucocyte mediated immunity" EXACT [] is_a: GO:0002698 ! negative regulation of immune effector process is_a: GO:0002703 ! regulation of leukocyte mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002443 ! leukocyte mediated immunity relationship: negatively_regulates GO:0002443 ! leukocyte mediated immunity [Term] id: GO:0002705 name: positive regulation of leukocyte mediated immunity namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of leukocyte mediated immunity." [GOC:add] synonym: "activation of leukocyte mediated immunity" NARROW [] synonym: "positive regulation of immune cell mediated immunity" EXACT [] synonym: "positive regulation of leucocyte mediated immunity" EXACT [] synonym: "stimulation of leukocyte mediated immunity" NARROW [] synonym: "up regulation of leukocyte mediated immunity" EXACT [] synonym: "up-regulation of leukocyte mediated immunity" EXACT [] synonym: "upregulation of leukocyte mediated immunity" EXACT [] is_a: GO:0002699 ! positive regulation of immune effector process is_a: GO:0002703 ! regulation of leukocyte mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002443 ! leukocyte mediated immunity relationship: positively_regulates GO:0002443 ! leukocyte mediated immunity [Term] id: GO:0002706 name: regulation of lymphocyte mediated immunity namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of lymphocyte mediated immunity." [GOC:add] is_a: GO:0002703 ! regulation of leukocyte mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002449 ! lymphocyte mediated immunity relationship: regulates GO:0002449 ! lymphocyte mediated immunity [Term] id: GO:0002707 name: negative regulation of lymphocyte mediated immunity namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte mediated immunity." [GOC:add] synonym: "down regulation of lymphocyte mediated immunity" EXACT [] synonym: "down-regulation of lymphocyte mediated immunity" EXACT [] synonym: "downregulation of lymphocyte mediated immunity" EXACT [] synonym: "inhibition of lymphocyte mediated immunity" NARROW [] is_a: GO:0002704 ! negative regulation of leukocyte mediated immunity is_a: GO:0002706 ! regulation of lymphocyte mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002449 ! lymphocyte mediated immunity relationship: negatively_regulates GO:0002449 ! lymphocyte mediated immunity [Term] id: GO:0002708 name: positive regulation of lymphocyte mediated immunity namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of lymphocyte mediated immunity." [GOC:add] synonym: "activation of lymphocyte mediated immunity" NARROW [] synonym: "stimulation of lymphocyte mediated immunity" NARROW [] synonym: "up regulation of lymphocyte mediated immunity" EXACT [] synonym: "up-regulation of lymphocyte mediated immunity" EXACT [] synonym: "upregulation of lymphocyte mediated immunity" EXACT [] is_a: GO:0002705 ! positive regulation of leukocyte mediated immunity is_a: GO:0002706 ! regulation of lymphocyte mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002449 ! lymphocyte mediated immunity relationship: positively_regulates GO:0002449 ! lymphocyte mediated immunity [Term] id: GO:0002709 name: regulation of T cell mediated immunity namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of T cell mediated immunity." [GOC:add] synonym: "regulation of T lymphocyte mediated immunity" EXACT [] synonym: "regulation of T-cell mediated immunity" EXACT [] synonym: "regulation of T-lymphocyte mediated immunity" EXACT [] is_a: GO:0002706 ! regulation of lymphocyte mediated immunity is_a: GO:0002822 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002456 ! T cell mediated immunity relationship: regulates GO:0002456 ! T cell mediated immunity [Term] id: GO:0002710 name: negative regulation of T cell mediated immunity namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated immunity." [GOC:add] synonym: "down regulation of T cell mediated immunity" EXACT [] synonym: "down-regulation of T cell mediated immunity" EXACT [] synonym: "downregulation of T cell mediated immunity" EXACT [] synonym: "inhibition of T cell mediated immunity" NARROW [] synonym: "negative regulation of T lymphocyte mediated immunity" EXACT [] synonym: "negative regulation of T-cell mediated immunity" EXACT [] synonym: "negative regulation of T-lymphocyte mediated immunity" EXACT [] is_a: GO:0002707 ! negative regulation of lymphocyte mediated immunity is_a: GO:0002709 ! regulation of T cell mediated immunity is_a: GO:0002823 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002456 ! T cell mediated immunity relationship: negatively_regulates GO:0002456 ! T cell mediated immunity [Term] id: GO:0002711 name: positive regulation of T cell mediated immunity namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of T cell mediated immunity." [GOC:add] synonym: "activation of T cell mediated immunity" NARROW [] synonym: "positive regulation of T lymphocyte mediated immunity" EXACT [] synonym: "positive regulation of T-cell mediated immunity" EXACT [] synonym: "positive regulation of T-lymphocyte mediated immunity" EXACT [] synonym: "stimulation of T cell mediated immunity" NARROW [] synonym: "up regulation of T cell mediated immunity" EXACT [] synonym: "up-regulation of T cell mediated immunity" EXACT [] synonym: "upregulation of T cell mediated immunity" EXACT [] is_a: GO:0002708 ! positive regulation of lymphocyte mediated immunity is_a: GO:0002709 ! regulation of T cell mediated immunity is_a: GO:0002824 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002456 ! T cell mediated immunity relationship: positively_regulates GO:0002456 ! T cell mediated immunity [Term] id: GO:0002718 name: regulation of cytokine production involved in immune response namespace: biological_process alt_id: GO:0002739 alt_id: GO:0002742 def: "Any process that modulates the frequency, rate, or extent of cytokine production that contributes to an immune response." [GOC:add] synonym: "regulation of cytokine biosynthetic process involved in immune response" NARROW [] synonym: "regulation of cytokine production during immune response" RELATED [GOC:dph] synonym: "regulation of cytokine secretion involved in immune response" NARROW [] is_a: GO:0001817 ! regulation of cytokine production is_a: GO:0002700 ! regulation of production of molecular mediator of immune response intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002367 ! cytokine production involved in immune response relationship: regulates GO:0002367 ! cytokine production involved in immune response [Term] id: GO:0002719 name: negative regulation of cytokine production involved in immune response namespace: biological_process alt_id: GO:0002740 alt_id: GO:0002743 def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine production contributing to an immune response." [GOC:add] synonym: "down regulation of cytokine production during immune response" RELATED [] synonym: "down-regulation of cytokine production during immune response" EXACT [] synonym: "downregulation of cytokine production during immune response" RELATED [] synonym: "inhibition of cytokine production during immune response" RELATED [] synonym: "negative regulation of cytokine biosynthetic process involved in immune response" NARROW [] synonym: "negative regulation of cytokine production during immune response" RELATED [GOC:dph] synonym: "negative regulation of cytokine secretion involved in immune response" NARROW [] is_a: GO:0001818 ! negative regulation of cytokine production is_a: GO:0002701 ! negative regulation of production of molecular mediator of immune response is_a: GO:0002718 ! regulation of cytokine production involved in immune response intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002367 ! cytokine production involved in immune response relationship: negatively_regulates GO:0002367 ! cytokine production involved in immune response [Term] id: GO:0002720 name: positive regulation of cytokine production involved in immune response namespace: biological_process alt_id: GO:0002741 alt_id: GO:0002744 def: "Any process that activates or increases the frequency, rate, or extent of cytokine production that contributes to an immune response." [GOC:add] synonym: "activation of cytokine production during immune response" NARROW [] synonym: "positive regulation of cytokine biosynthetic process involved in immune response" NARROW [] synonym: "positive regulation of cytokine production during immune response" RELATED [GOC:dph] synonym: "positive regulation of cytokine secretion involved in immune response" NARROW [] synonym: "stimulation of cytokine production during immune response" NARROW [] synonym: "up regulation of cytokine production during immune response" RELATED [] synonym: "up-regulation of cytokine production during immune response" RELATED [] synonym: "upregulation of cytokine production during immune response" RELATED [] is_a: GO:0001819 ! positive regulation of cytokine production is_a: GO:0002702 ! positive regulation of production of molecular mediator of immune response is_a: GO:0002718 ! regulation of cytokine production involved in immune response intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002367 ! cytokine production involved in immune response relationship: positively_regulates GO:0002367 ! cytokine production involved in immune response [Term] id: GO:0002724 name: regulation of T cell cytokine production namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of T cell cytokine production." [GOC:add] synonym: "regulation of T lymphocyte cytokine production" EXACT [] synonym: "regulation of T-cell cytokine production" EXACT [] synonym: "regulation of T-lymphocyte cytokine production" EXACT [] is_a: GO:0002709 ! regulation of T cell mediated immunity is_a: GO:0002718 ! regulation of cytokine production involved in immune response intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002369 ! T cell cytokine production relationship: regulates GO:0002369 ! T cell cytokine production [Term] id: GO:0002725 name: negative regulation of T cell cytokine production namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell cytokine production." [GOC:add] synonym: "down regulation of T cell cytokine production" EXACT [] synonym: "down-regulation of T cell cytokine production" EXACT [] synonym: "downregulation of T cell cytokine production" EXACT [] synonym: "inhibition of T cell cytokine production" NARROW [] synonym: "negative regulation of T lymphocyte cytokine production" EXACT [] synonym: "negative regulation of T-cell cytokine production" EXACT [] synonym: "negative regulation of T-lymphocyte cytokine production" EXACT [] is_a: GO:0002710 ! negative regulation of T cell mediated immunity is_a: GO:0002719 ! negative regulation of cytokine production involved in immune response is_a: GO:0002724 ! regulation of T cell cytokine production intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002369 ! T cell cytokine production relationship: negatively_regulates GO:0002369 ! T cell cytokine production [Term] id: GO:0002726 name: positive regulation of T cell cytokine production namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of T cell cytokine production." [GOC:add] synonym: "activation of T cell cytokine production" NARROW [] synonym: "positive regulation of T lymphocyte cytokine production" EXACT [] synonym: "positive regulation of T-cell cytokine production" EXACT [] synonym: "positive regulation of T-lymphocyte cytokine production" EXACT [] synonym: "stimulation of T cell cytokine production" NARROW [] synonym: "up regulation of T cell cytokine production" EXACT [] synonym: "up-regulation of T cell cytokine production" EXACT [] synonym: "upregulation of T cell cytokine production" EXACT [] is_a: GO:0002711 ! positive regulation of T cell mediated immunity is_a: GO:0002720 ! positive regulation of cytokine production involved in immune response is_a: GO:0002724 ! regulation of T cell cytokine production intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002369 ! T cell cytokine production relationship: positively_regulates GO:0002369 ! T cell cytokine production [Term] id: GO:0002730 name: regulation of dendritic cell cytokine production namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of dendritic cell cytokine production." [GOC:add] is_a: GO:0002703 ! regulation of leukocyte mediated immunity is_a: GO:0002718 ! regulation of cytokine production involved in immune response intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002371 ! dendritic cell cytokine production relationship: regulates GO:0002371 ! dendritic cell cytokine production [Term] id: GO:0002731 name: negative regulation of dendritic cell cytokine production namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell cytokine production." [GOC:add] synonym: "down regulation of dendritic cell cytokine production" EXACT [] synonym: "down-regulation of dendritic cell cytokine production" EXACT [] synonym: "downregulation of dendritic cell cytokine production" EXACT [] synonym: "inhibition of dendritic cell cytokine production" NARROW [] is_a: GO:0002704 ! negative regulation of leukocyte mediated immunity is_a: GO:0002719 ! negative regulation of cytokine production involved in immune response is_a: GO:0002730 ! regulation of dendritic cell cytokine production intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002371 ! dendritic cell cytokine production relationship: negatively_regulates GO:0002371 ! dendritic cell cytokine production [Term] id: GO:0002732 name: positive regulation of dendritic cell cytokine production namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of dendritic cell cytokine production." [GOC:add] synonym: "activation of dendritic cell cytokine production" NARROW [] synonym: "stimulation of dendritic cell cytokine production" NARROW [] synonym: "up regulation of dendritic cell cytokine production" EXACT [] synonym: "up-regulation of dendritic cell cytokine production" EXACT [] synonym: "upregulation of dendritic cell cytokine production" EXACT [] is_a: GO:0002705 ! positive regulation of leukocyte mediated immunity is_a: GO:0002720 ! positive regulation of cytokine production involved in immune response is_a: GO:0002730 ! regulation of dendritic cell cytokine production intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002371 ! dendritic cell cytokine production relationship: positively_regulates GO:0002371 ! dendritic cell cytokine production [Term] id: GO:0002761 name: regulation of myeloid leukocyte differentiation namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of myeloid leukocyte differentiation." [GOC:add] is_a: GO:0045637 ! regulation of myeloid cell differentiation is_a: GO:1902105 ! regulation of leukocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002573 ! myeloid leukocyte differentiation relationship: regulates GO:0002573 ! myeloid leukocyte differentiation [Term] id: GO:0002762 name: negative regulation of myeloid leukocyte differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte differentiation." [GOC:add] synonym: "down regulation of myeloid leukocyte differentiation" EXACT [] synonym: "down-regulation of myeloid leukocyte differentiation" EXACT [] synonym: "downregulation of myeloid leukocyte differentiation" EXACT [] synonym: "inhibition of myeloid leukocyte differentiation" NARROW [] is_a: GO:0002761 ! regulation of myeloid leukocyte differentiation is_a: GO:0045638 ! negative regulation of myeloid cell differentiation is_a: GO:1902106 ! negative regulation of leukocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002573 ! myeloid leukocyte differentiation relationship: negatively_regulates GO:0002573 ! myeloid leukocyte differentiation [Term] id: GO:0002763 name: positive regulation of myeloid leukocyte differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte differentiation." [GOC:add] synonym: "activation of myeloid leukocyte differentiation" NARROW [] synonym: "stimulation of myeloid leukocyte differentiation" NARROW [] synonym: "up regulation of myeloid leukocyte differentiation" EXACT [] synonym: "up-regulation of myeloid leukocyte differentiation" EXACT [] synonym: "upregulation of myeloid leukocyte differentiation" EXACT [] is_a: GO:0002761 ! regulation of myeloid leukocyte differentiation is_a: GO:0045639 ! positive regulation of myeloid cell differentiation is_a: GO:1902107 ! positive regulation of leukocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002573 ! myeloid leukocyte differentiation relationship: positively_regulates GO:0002573 ! myeloid leukocyte differentiation [Term] id: GO:0002790 name: peptide secretion namespace: biological_process def: "The controlled release of a peptide from a cell or a tissue." [GOC:add] is_a: GO:0015833 ! peptide transport is_a: GO:0046903 ! secretion intersection_of: GO:0046903 ! secretion intersection_of: has_primary_input CHEBI:16670 ! peptide [Term] id: GO:0002791 name: regulation of peptide secretion namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of peptide secretion." [GOC:add] is_a: GO:0051046 ! regulation of secretion is_a: GO:0090087 ! regulation of peptide transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002790 ! peptide secretion relationship: regulates GO:0002790 ! peptide secretion [Term] id: GO:0002792 name: negative regulation of peptide secretion namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of peptide secretion." [GOC:add] synonym: "down regulation of peptide secretion" EXACT [] synonym: "down-regulation of peptide secretion" EXACT [] synonym: "downregulation of peptide secretion" EXACT [] synonym: "inhibition of peptide secretion" NARROW [] is_a: GO:0002791 ! regulation of peptide secretion is_a: GO:0051048 ! negative regulation of secretion intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002790 ! peptide secretion relationship: negatively_regulates GO:0002790 ! peptide secretion [Term] id: GO:0002793 name: positive regulation of peptide secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of peptide secretion." [GOC:add] synonym: "activation of peptide secretion" NARROW [] synonym: "stimulation of peptide secretion" NARROW [] synonym: "up regulation of peptide secretion" EXACT [] synonym: "up-regulation of peptide secretion" EXACT [] synonym: "upregulation of peptide secretion" EXACT [] is_a: GO:0002791 ! regulation of peptide secretion is_a: GO:0051047 ! positive regulation of secretion intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002790 ! peptide secretion relationship: positively_regulates GO:0002790 ! peptide secretion [Term] id: GO:0002819 name: regulation of adaptive immune response namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of an adaptive immune response." [GOC:add] is_a: GO:0050776 ! regulation of immune response intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002250 ! adaptive immune response relationship: regulates GO:0002250 ! adaptive immune response [Term] id: GO:0002820 name: negative regulation of adaptive immune response namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response." [GOC:add] synonym: "down regulation of adaptive immune response" EXACT [] synonym: "down-regulation of adaptive immune response" EXACT [] synonym: "downregulation of adaptive immune response" EXACT [] synonym: "inhibition of adaptive immune response" NARROW [] is_a: GO:0002819 ! regulation of adaptive immune response is_a: GO:0050777 ! negative regulation of immune response intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002250 ! adaptive immune response relationship: negatively_regulates GO:0002250 ! adaptive immune response [Term] id: GO:0002821 name: positive regulation of adaptive immune response namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of an adaptive immune response." [GOC:add] synonym: "activation of adaptive immune response" NARROW [] synonym: "stimulation of adaptive immune response" NARROW [] synonym: "up regulation of adaptive immune response" EXACT [] synonym: "up-regulation of adaptive immune response" EXACT [] synonym: "upregulation of adaptive immune response" EXACT [] is_a: GO:0002819 ! regulation of adaptive immune response is_a: GO:0050778 ! positive regulation of immune response intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002250 ! adaptive immune response relationship: positively_regulates GO:0002250 ! adaptive immune response [Term] id: GO:0002822 name: regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata." [GOC:add, GOC:mtg_sensu] is_a: GO:0002819 ! regulation of adaptive immune response intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002460 ! adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains relationship: in_taxon NCBITaxon:7776 {all_only="true"} ! Gnathostomata relationship: only_in_taxon NCBITaxon:7776 ! Gnathostomata relationship: regulates GO:0002460 ! adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [Term] id: GO:0002823 name: negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata." [GOC:add, GOC:mtg_sensu] is_a: GO:0002820 ! negative regulation of adaptive immune response is_a: GO:0002822 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002460 ! adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains relationship: negatively_regulates GO:0002460 ! adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [Term] id: GO:0002824 name: positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata." [GOC:add, GOC:mtg_sensu] is_a: GO:0002821 ! positive regulation of adaptive immune response is_a: GO:0002822 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002460 ! adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains relationship: positively_regulates GO:0002460 ! adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [Term] id: GO:0002831 name: regulation of response to biotic stimulus namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of a response to biotic stimulus." [GOC:add] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_manually_annotate is_a: GO:0048583 ! regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0009607 ! response to biotic stimulus relationship: regulates GO:0009607 ! response to biotic stimulus [Term] id: GO:0002832 name: negative regulation of response to biotic stimulus namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to biotic stimulus." [GOC:add] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_manually_annotate synonym: "down regulation of response to biotic stimulus" EXACT [] synonym: "down-regulation of response to biotic stimulus" EXACT [] synonym: "downregulation of response to biotic stimulus" EXACT [] synonym: "inhibition of response to biotic stimulus" NARROW [] is_a: GO:0002831 ! regulation of response to biotic stimulus is_a: GO:0048585 ! negative regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0009607 ! response to biotic stimulus relationship: negatively_regulates GO:0009607 ! response to biotic stimulus [Term] id: GO:0002833 name: positive regulation of response to biotic stimulus namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of a response to biotic stimulus." [GOC:add] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_manually_annotate synonym: "activation of response to biotic stimulus" NARROW [] synonym: "stimulation of response to biotic stimulus" NARROW [] synonym: "up regulation of response to biotic stimulus" EXACT [] synonym: "up-regulation of response to biotic stimulus" EXACT [] synonym: "upregulation of response to biotic stimulus" EXACT [] is_a: GO:0002831 ! regulation of response to biotic stimulus is_a: GO:0048584 ! positive regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0009607 ! response to biotic stimulus relationship: positively_regulates GO:0009607 ! response to biotic stimulus [Term] id: GO:0002886 name: regulation of myeloid leukocyte mediated immunity namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of myeloid leukocyte mediated immunity." [GOC:add] is_a: GO:0002703 ! regulation of leukocyte mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002444 ! myeloid leukocyte mediated immunity relationship: regulates GO:0002444 ! myeloid leukocyte mediated immunity [Term] id: GO:0002887 name: negative regulation of myeloid leukocyte mediated immunity namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte mediated immunity." [GOC:add] synonym: "down regulation of myeloid leukocyte mediated immunity" EXACT [] synonym: "down-regulation of myeloid leukocyte mediated immunity" EXACT [] synonym: "downregulation of myeloid leukocyte mediated immunity" EXACT [] synonym: "inhibition of myeloid leukocyte mediated immunity" NARROW [] is_a: GO:0002704 ! negative regulation of leukocyte mediated immunity is_a: GO:0002886 ! regulation of myeloid leukocyte mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002444 ! myeloid leukocyte mediated immunity relationship: negatively_regulates GO:0002444 ! myeloid leukocyte mediated immunity [Term] id: GO:0002888 name: positive regulation of myeloid leukocyte mediated immunity namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte mediated immunity." [GOC:add] synonym: "activation of myeloid leukocyte mediated immunity" NARROW [] synonym: "stimulation of myeloid leukocyte mediated immunity" NARROW [] synonym: "up regulation of myeloid leukocyte mediated immunity" EXACT [] synonym: "up-regulation of myeloid leukocyte mediated immunity" EXACT [] synonym: "upregulation of myeloid leukocyte mediated immunity" EXACT [] is_a: GO:0002705 ! positive regulation of leukocyte mediated immunity is_a: GO:0002886 ! regulation of myeloid leukocyte mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002444 ! myeloid leukocyte mediated immunity relationship: positively_regulates GO:0002444 ! myeloid leukocyte mediated immunity [Term] id: GO:0002932 name: tendon sheath development namespace: biological_process def: "The process whose specific outcome is the progression of a tendon sheath over time, from its formation to the mature structure. A tendon sheath is a layer of membrane around a tendon. It permits the tendon to move." [PMID:20696843] is_a: GO:0061448 ! connective tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000304 ! tendon sheath relationship: part_of GO:0035989 ! tendon development relationship: results_in_development_of UBERON:0000304 ! tendon sheath created_by: hjd creation_date: 2012-04-23T02:11:22Z [Term] id: GO:0003002 name: regionalization namespace: biological_process def: "The pattern specification process that results in the subdivision of an axis or axes in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment." [GOC:dph, GOC:isa_complete] synonym: "pattern formation" RELATED [GOC:dph] is_a: GO:0007389 ! pattern specification process [Term] id: GO:0003006 name: developmental process involved in reproduction namespace: biological_process def: "A developmental process in which a progressive change in the state of some part of an organism, germline or somatic, specifically contributes to its ability to form offspring." [GOC:dph, GOC:isa_complete] synonym: "puberty" NARROW [GOC:dph] synonym: "reproductive developmental process" RELATED [GOC:dph, GOC:tb] is_a: GO:0022414 ! reproductive process is_a: GO:0032502 ! developmental process intersection_of: GO:0032502 ! developmental process intersection_of: part_of GO:0000003 ! reproduction [Term] id: GO:0003007 name: heart morphogenesis namespace: biological_process def: "The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood." [GOC:dph, GOC:isa_complete] synonym: "cardiac morphogenesis" RELATED [] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0007100 ! primary circulatory organ relationship: part_of GO:0007507 ! heart development relationship: results_in_morphogenesis_of UBERON:0007100 ! primary circulatory organ [Term] id: GO:0003008 name: system process namespace: biological_process def: "A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective." [GOC:mtg_cardio] synonym: "organ system process" EXACT [] is_a: GO:0032501 ! multicellular organismal process [Term] id: GO:0003009 name: skeletal muscle contraction namespace: biological_process def: "A process in which force is generated within skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and in most cases it is under voluntary control." [GOC:mtg_cardio, GOC:mtg_muscle] is_a: GO:0006941 ! striated muscle contraction intersection_of: GO:0006936 ! muscle contraction intersection_of: occurs_in UBERON:0001134 ! skeletal muscle tissue relationship: occurs_in UBERON:0001134 ! skeletal muscle tissue relationship: part_of GO:0050881 ! musculoskeletal movement [Term] id: GO:0003012 name: muscle system process namespace: biological_process def: "A organ system process carried out at the level of a muscle. Muscle tissue is composed of contractile cells or fibers." [GOC:mtg_cardio] subset: goslim_drosophila subset: goslim_generic synonym: "muscle physiological process" RELATED [] is_a: GO:0003008 ! system process [Term] id: GO:0003013 name: circulatory system process namespace: biological_process def: "A organ system process carried out by any of the organs or tissues of the circulatory system. The circulatory system is an organ system that moves extracellular fluids to and from tissue within a multicellular organism." [GOC:mtg_cardio] subset: goslim_chembl subset: goslim_generic xref: Wikipedia:Circulatory_system is_a: GO:0003008 ! system process [Term] id: GO:0003014 name: renal system process namespace: biological_process def: "A organ system process carried out by any of the organs or tissues of the renal system. The renal system maintains fluid balance, and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels; in other species, the renal system may comprise related structures (e.g., nephrocytes and malpighian tubules in Drosophila)." [GOC:cjm, GOC:mtg_cardio, GOC:mtg_kidney_jan10] subset: goslim_generic synonym: "excretory system process" EXACT [] synonym: "kidney system process" RELATED [] is_a: GO:0003008 ! system process [Term] id: GO:0003015 name: heart process namespace: biological_process def: "A circulatory system process carried out by the heart. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood." [GOC:mtg_cardio] synonym: "cardiac process" RELATED [] is_a: GO:0003013 ! circulatory system process [Term] id: GO:0003016 name: respiratory system process namespace: biological_process alt_id: GO:0010802 def: "A process carried out by the organs or tissues of the respiratory system. The respiratory system is an organ system responsible for respiratory gaseous exchange." [GOC:dph, GOC:mtg_cardio, GOC:tb] subset: goslim_generic synonym: "respiratory gaseous exchange" EXACT [] is_a: GO:0003008 ! system process relationship: part_of GO:0007585 ! respiratory gaseous exchange by respiratory system [Term] id: GO:0003032 name: detection of oxygen namespace: biological_process def: "The series of events in which an oxygen stimulus is received by a cell and converted into a molecular signal." [GOC:mtg_cardio] is_a: GO:0009593 ! detection of chemical stimulus is_a: GO:0070482 ! response to oxygen levels [Term] id: GO:0003096 name: renal sodium ion transport namespace: biological_process def: "The directed movement of sodium ions (Na+) by the renal system." [GOC:mtg_cardio] is_a: GO:0003014 ! renal system process is_a: GO:0006814 ! sodium ion transport intersection_of: GO:0006814 ! sodium ion transport intersection_of: occurs_in UBERON:0001008 ! renal system relationship: occurs_in UBERON:0001008 ! renal system [Term] id: GO:0003131 name: mesodermal-endodermal cell signaling namespace: biological_process def: "Any process that mediates the transfer of information from mesodermal cells to endodermal cells." [GOC:mtg_heart] synonym: "mesodermal-endodermal cell signalling" EXACT [GOC:mah] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: has_end_location CL:0000223 ! endodermal cell intersection_of: has_start_location CL:0000222 ! mesodermal cell relationship: has_end_location CL:0000223 ! endodermal cell relationship: has_start_location CL:0000222 ! mesodermal cell created_by: tb creation_date: 2009-09-22T03:07:34Z [Term] id: GO:0003133 name: endodermal-mesodermal cell signaling namespace: biological_process def: "Any process that mediates the transfer of information from endodermal cells to mesodermal cells." [GOC:mtg_heart] synonym: "endodermal-mesodermal cell signalling" EXACT [GOC:mah] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: has_end_location CL:0000222 ! mesodermal cell intersection_of: has_start_location CL:0000223 ! endodermal cell relationship: has_end_location CL:0000222 ! mesodermal cell relationship: has_start_location CL:0000223 ! endodermal cell created_by: tb creation_date: 2009-09-22T03:10:29Z [Term] id: GO:0003142 name: cardiogenic plate morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the cardiogenic plate are generated and organized. The cardiogenic plate is the first recognizable structure derived from the heart field." [GOC:mtg_heart] synonym: "cardiac crescent morphogenesis" EXACT [GOC:mtg_heart] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0004139 ! cardiogenic plate relationship: part_of GO:0003007 ! heart morphogenesis relationship: results_in_morphogenesis_of UBERON:0004139 ! cardiogenic plate created_by: tb creation_date: 2009-09-22T04:12:18Z [Term] id: GO:0003143 name: embryonic heart tube morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the embryonic heart tube are generated and organized. The embryonic heart tube is an epithelial tube that will give rise to the mature heart." [GOC:mtg_heart] is_a: GO:0048598 ! embryonic morphogenesis is_a: GO:0060562 ! epithelial tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0004141 ! heart tube relationship: part_of GO:0003007 ! heart morphogenesis relationship: part_of GO:0035050 ! embryonic heart tube development relationship: part_of GO:0048562 ! embryonic organ morphogenesis relationship: results_in_morphogenesis_of UBERON:0004141 ! heart tube created_by: tb creation_date: 2009-09-22T04:21:17Z [Term] id: GO:0003144 name: embryonic heart tube formation namespace: biological_process def: "The process that gives rise to the embryonic heart tube. This process pertains to the initial formation of a structure from unspecified parts. The embryonic heart tube is an epithelial tube that will give rise to the mature heart." [GOC:mtg_heart] is_a: GO:0001838 ! embryonic epithelial tube formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0004141 ! heart tube relationship: part_of GO:0003143 ! embryonic heart tube morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0004141 ! heart tube created_by: tb creation_date: 2009-09-22T04:22:34Z [Term] id: GO:0003145 name: embryonic heart tube formation via epithelial folding namespace: biological_process def: "The process that gives rise to the embryonic heart tube by the cells of the heart field along a linear axis." [GOC:mtg_heart] is_a: GO:0003144 ! embryonic heart tube formation created_by: tb creation_date: 2009-09-22T04:26:03Z [Term] id: GO:0003147 name: neural crest cell migration involved in heart formation namespace: biological_process def: "The characteristic movement of a cell from the dorsal ridge of the neural tube towards the heart and that contributes to heart formation." [GOC:mtg_heart] is_a: GO:0001755 ! neural crest cell migration is_a: GO:0060974 ! cell migration involved in heart formation intersection_of: GO:0001755 ! neural crest cell migration intersection_of: part_of GO:0060914 ! heart formation relationship: part_of GO:0061308 ! cardiac neural crest cell development involved in heart development created_by: tb creation_date: 2009-09-22T04:29:55Z [Term] id: GO:0003148 name: outflow tract septum morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the outflow tract septum are generated and organized. The outflow tract septum is a partition in the outflow tract." [GOC:mtg_heart] is_a: GO:0060411 ! cardiac septum morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0004142 ! outflow tract septum relationship: part_of GO:0003151 ! outflow tract morphogenesis relationship: results_in_morphogenesis_of UBERON:0004142 ! outflow tract septum created_by: tb creation_date: 2009-09-22T07:51:01Z [Term] id: GO:0003149 name: membranous septum morphogenesis namespace: biological_process def: "The process in which the membranous septum is generated and organized. The membranous septum is the upper part of ventricular septum." [GOC:mtg_heart] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0004666 ! interventricular septum membranous part relationship: part_of GO:0060412 ! ventricular septum morphogenesis relationship: results_in_morphogenesis_of UBERON:0004666 ! interventricular septum membranous part created_by: tb creation_date: 2009-09-22T07:51:41Z [Term] id: GO:0003150 name: muscular septum morphogenesis namespace: biological_process def: "The process in which the muscular septum is generated and organized. The muscular septum is the lower part of the ventricular septum." [GOC:mtg_heart] is_a: GO:0060415 ! muscle tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0004667 ! interventricular septum muscular part relationship: part_of GO:0060412 ! ventricular septum morphogenesis relationship: results_in_morphogenesis_of UBERON:0004667 ! interventricular septum muscular part created_by: tb creation_date: 2009-09-22T07:53:28Z [Term] id: GO:0003151 name: outflow tract morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries." [GOC:mtg_heart, UBERON:0004145] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0004145 ! outflow tract relationship: part_of GO:0003007 ! heart morphogenesis relationship: results_in_morphogenesis_of UBERON:0004145 ! outflow tract created_by: tb creation_date: 2009-09-22T07:59:24Z [Term] id: GO:0003152 name: morphogenesis of an epithelial fold involved in embryonic heart tube formation namespace: biological_process def: "The morphogenetic process in which an epithelial sheet bends along a linear axis, contributing to embryonic heart tube formation." [GOC:mtg_heart] is_a: GO:0048598 ! embryonic morphogenesis is_a: GO:0060571 ! morphogenesis of an epithelial fold intersection_of: GO:0060571 ! morphogenesis of an epithelial fold intersection_of: part_of GO:0003144 ! embryonic heart tube formation relationship: part_of GO:0003145 ! embryonic heart tube formation via epithelial folding created_by: tb creation_date: 2009-09-23T10:10:24Z [Term] id: GO:0003156 name: regulation of animal organ formation namespace: biological_process def: "Any process that modulates the rate, frequency or extent of animal organ formation. Organ formation is the process pertaining to the initial formation of an organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment." [GOC:dph, GOC:mtg_heart, GOC:tb] is_a: GO:2000027 ! regulation of animal organ morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048645 ! animal organ formation relationship: regulates GO:0048645 ! animal organ formation created_by: tb creation_date: 2009-09-30T11:21:09Z [Term] id: GO:0003157 name: endocardium development namespace: biological_process def: "The process whose specific outcome is the progression of the endocardium over time, from its formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers." [GOC:mtg_heart] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002165 ! endocardium relationship: part_of GO:0007507 ! heart development relationship: results_in_development_of UBERON:0002165 ! endocardium created_by: dph creation_date: 2009-10-01T12:42:27Z [Term] id: GO:0003158 name: endothelium development namespace: biological_process def: "The process whose specific outcome is the progression of an endothelium over time, from its formation to the mature structure. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells." [GOC:mtg_heart] is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001986 ! endothelium relationship: results_in_development_of UBERON:0001986 ! endothelium created_by: dph creation_date: 2009-10-01T12:50:57Z [Term] id: GO:0003159 name: morphogenesis of an endothelium namespace: biological_process def: "The process in which the anatomical structure of an endothelium is generated and organized. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells." [GOC:mtg_heart] is_a: GO:0002009 ! morphogenesis of an epithelium intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001986 ! endothelium relationship: part_of GO:0003158 ! endothelium development relationship: results_in_morphogenesis_of UBERON:0001986 ! endothelium created_by: dph creation_date: 2009-10-01T01:34:06Z [Term] id: GO:0003160 name: endocardium morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the endocardium is generated and organized. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers." [GOC:mtg_heart] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002165 ! endocardium relationship: part_of GO:0003157 ! endocardium development relationship: results_in_morphogenesis_of UBERON:0002165 ! endocardium created_by: dph creation_date: 2009-10-01T01:37:26Z [Term] id: GO:0003161 name: cardiac conduction system development namespace: biological_process def: "The process whose specific outcome is the progression of the cardiac conduction system over time, from its formation to the mature structure. The cardiac conduction system consists of specialized cardiomyocytes that regulate the frequency of heart beat." [GOC:mtg_heart] synonym: "cardiac impulse conducting system development" EXACT [GOC:mtg_heart] synonym: "heart conduction system development" EXACT [GOC:mtg_heart] is_a: GO:0048738 ! cardiac muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002350 ! conducting system of heart relationship: results_in_development_of UBERON:0002350 ! conducting system of heart created_by: dph creation_date: 2009-10-01T01:57:16Z [Term] id: GO:0003162 name: atrioventricular node development namespace: biological_process def: "The process whose specific outcome is the progression of the atrioventricular (AV) node over time, from its formation to the mature structure. The AV node is part of the cardiac conduction system that controls the timing of ventricle contraction by receiving electrical signals from the sinoatrial (SA) node and relaying them to the His-Purkinje system." [GOC:mtg_heart] synonym: "AV node development" EXACT [GOC:mtg_heart] is_a: GO:0048738 ! cardiac muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002352 ! atrioventricular node relationship: part_of GO:0003161 ! cardiac conduction system development relationship: results_in_development_of UBERON:0002352 ! atrioventricular node created_by: dph creation_date: 2009-10-01T02:05:13Z [Term] id: GO:0003163 name: sinoatrial node development namespace: biological_process def: "The process whose specific outcome is the progression of the sinoatrial (SA) node over time, from its formation to the mature structure. The SA node is part of the cardiac conduction system that controls the timing of heart muscle contraction. It relays electrical signals to the AV node." [GOC:mtg_heart] synonym: "SA node development" EXACT [GOC:mtg_heart] synonym: "SAN development" EXACT [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "sinus node development" NARROW [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] is_a: GO:0003228 ! atrial cardiac muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002351 ! sinoatrial node relationship: part_of GO:0003161 ! cardiac conduction system development relationship: results_in_development_of UBERON:0002351 ! sinoatrial node created_by: dph creation_date: 2009-10-01T02:06:09Z [Term] id: GO:0003164 name: His-Purkinje system development namespace: biological_process def: "The process whose specific outcome is the progression of the His-Purkinje system over time, from its formation to the mature structure. The His-Purkinje system receives signals from the AV node and is composed of the fibers that regulate cardiac muscle contraction in the ventricles." [GOC:mtg_heart] is_a: GO:0003229 ! ventricular cardiac muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004146 ! His-Purkinje system relationship: part_of GO:0003161 ! cardiac conduction system development relationship: results_in_development_of UBERON:0004146 ! His-Purkinje system created_by: dph creation_date: 2009-10-01T02:07:12Z [Term] id: GO:0003165 name: Purkinje myocyte development namespace: biological_process def: "The process whose specific outcome is the progression of a Purkinje myocyte over time, from its formation to the mature structure. The Purkinje myocyte (also known as cardiac Purkinje fiber) is part of the cardiac conduction system that receives signals from the bundle of His and innervates the ventricular cardiac muscle." [GOC:mtg_cardiac_conduct_nov11, GOC:mtg_heart] synonym: "cardiac Purkinje fiber development" EXACT [] is_a: GO:0003229 ! ventricular cardiac muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002354 ! cardiac Purkinje fiber relationship: part_of GO:0003164 ! His-Purkinje system development relationship: results_in_development_of UBERON:0002354 ! cardiac Purkinje fiber created_by: dph creation_date: 2009-10-01T02:07:50Z [Term] id: GO:0003168 name: Purkinje myocyte differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a Purkinje myocyte (also known as cardiac Purkinje fiber cell). These cells are specialized cardiomyocytes that receive signals from the bundle of His and innervate the ventricular cardiac muscle." [GOC:mtg_cardiac_conduct_nov11, GOC:mtg_heart] synonym: "cardiac Purkinje fiber cell differentiation" EXACT [] is_a: GO:0060932 ! His-Purkinje system cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0002068 ! Purkinje myocyte relationship: part_of GO:0003165 ! Purkinje myocyte development relationship: results_in_acquisition_of_features_of CL:0002068 ! Purkinje myocyte created_by: dph creation_date: 2009-10-01T02:49:54Z [Term] id: GO:0003169 name: coronary vein morphogenesis namespace: biological_process def: "The process in which the anatomical structures of veins of the heart are generated and organized." [GOC:mtg_heart] is_a: GO:0048845 ! venous blood vessel morphogenesis is_a: GO:0060977 ! coronary vasculature morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0004148 ! cardiac vein relationship: results_in_morphogenesis_of UBERON:0004148 ! cardiac vein created_by: dph creation_date: 2009-10-08T10:45:41Z [Term] id: GO:0003197 name: endocardial cushion development namespace: biological_process def: "The progression of a cardiac cushion over time, from its initial formation to the mature structure. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves." [GOC:mtg_heart] is_a: GO:0060485 ! mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002062 ! endocardial cushion relationship: part_of GO:0007507 ! heart development relationship: results_in_development_of UBERON:0002062 ! endocardial cushion created_by: dph creation_date: 2009-10-08T01:17:43Z [Term] id: GO:0003203 name: endocardial cushion morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the endocardial cushion is generated and organized. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves." [GOC:mtg_heart] is_a: GO:0072132 ! mesenchyme morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002062 ! endocardial cushion relationship: part_of GO:0003007 ! heart morphogenesis relationship: part_of GO:0003197 ! endocardial cushion development relationship: results_in_morphogenesis_of UBERON:0002062 ! endocardial cushion created_by: dph creation_date: 2009-10-08T01:43:22Z [Term] id: GO:0003204 name: cardiac skeleton development namespace: biological_process def: "The progression of the cardiac skeleton over time, from its formation to the mature structure. The cardiac skeleton is a specialized extracellular matrix that separates the atria from the ventricles and provides physical support for the heart." [GOC:mtg_heart] synonym: "heart fibrous skeleton development" EXACT [GOC:mtg_heart] is_a: GO:0061448 ! connective tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004292 ! cardiac skeleton relationship: part_of GO:0007507 ! heart development relationship: results_in_development_of UBERON:0004292 ! cardiac skeleton created_by: dph creation_date: 2009-10-13T09:05:04Z [Term] id: GO:0003205 name: cardiac chamber development namespace: biological_process def: "The progression of a cardiac chamber over time, from its formation to the mature structure. A cardiac chamber is an enclosed cavity within the heart." [GOC:mtg_heart] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004151 ! cardiac chamber relationship: part_of GO:0007507 ! heart development relationship: results_in_development_of UBERON:0004151 ! cardiac chamber created_by: dph creation_date: 2009-10-13T09:11:18Z [Term] id: GO:0003206 name: cardiac chamber morphogenesis namespace: biological_process def: "The process in which a cardiac chamber is generated and organized. A cardiac chamber is an enclosed cavity within the heart." [GOC:mtg_heart] synonym: "heart chamber morphogenesis" EXACT [GOC:mtg_heart] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0004151 ! cardiac chamber relationship: part_of GO:0003007 ! heart morphogenesis relationship: part_of GO:0003205 ! cardiac chamber development relationship: results_in_morphogenesis_of UBERON:0004151 ! cardiac chamber created_by: dph creation_date: 2009-10-13T09:14:51Z [Term] id: GO:0003207 name: cardiac chamber formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a cardiac chamber from unspecified parts. A cardiac chamber is an enclosed cavity within the heart." [GOC:mtg_heart] synonym: "heart chamber formation" EXACT [GOC:mtg_heart] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0004151 ! cardiac chamber relationship: part_of GO:0003206 ! cardiac chamber morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0004151 ! cardiac chamber created_by: dph creation_date: 2009-10-13T09:29:13Z [Term] id: GO:0003208 name: cardiac ventricle morphogenesis namespace: biological_process def: "The process in which the cardiac ventricle is generated and organized. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart." [GOC:mtg_heart] is_a: GO:0003206 ! cardiac chamber morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002082 ! cardiac ventricle relationship: part_of GO:0003231 ! cardiac ventricle development relationship: results_in_morphogenesis_of UBERON:0002082 ! cardiac ventricle created_by: dph creation_date: 2009-10-13T09:38:44Z [Term] id: GO:0003209 name: cardiac atrium morphogenesis namespace: biological_process def: "The process in which the cardiac atrium is generated and organized. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle." [GOC:mtg_heart] is_a: GO:0003206 ! cardiac chamber morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002081 ! cardiac atrium relationship: part_of GO:0003230 ! cardiac atrium development relationship: results_in_morphogenesis_of UBERON:0002081 ! cardiac atrium created_by: dph creation_date: 2009-10-13T09:39:44Z [Term] id: GO:0003210 name: cardiac atrium formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a cardiac atrium from unspecified parts. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle." [GOC:mtg_heart] is_a: GO:0003207 ! cardiac chamber formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0002081 ! cardiac atrium relationship: part_of GO:0003209 ! cardiac atrium morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0002081 ! cardiac atrium created_by: dph creation_date: 2009-10-13T09:44:25Z [Term] id: GO:0003211 name: cardiac ventricle formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a cardiac ventricle from unspecified parts. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart." [GOC:mtg_heart] is_a: GO:0003207 ! cardiac chamber formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0002082 ! cardiac ventricle relationship: part_of GO:0003208 ! cardiac ventricle morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0002082 ! cardiac ventricle created_by: dph creation_date: 2009-10-13T09:46:27Z [Term] id: GO:0003212 name: cardiac left atrium morphogenesis namespace: biological_process def: "The process in which the left cardiac atrium is generated and organized." [GOC:mtg_heart] is_a: GO:0003209 ! cardiac atrium morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002079 ! left cardiac atrium relationship: results_in_morphogenesis_of UBERON:0002079 ! left cardiac atrium created_by: dph creation_date: 2009-10-13T09:48:16Z [Term] id: GO:0003213 name: cardiac right atrium morphogenesis namespace: biological_process def: "The process in which the right cardiac atrium is generated and organized." [GOC:mtg_heart] is_a: GO:0003209 ! cardiac atrium morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002078 ! right cardiac atrium relationship: results_in_morphogenesis_of UBERON:0002078 ! right cardiac atrium created_by: dph creation_date: 2009-10-13T09:49:03Z [Term] id: GO:0003214 name: cardiac left ventricle morphogenesis namespace: biological_process def: "The process in which the left cardiac ventricle is generated and organized." [GOC:mtg_heart] is_a: GO:0003208 ! cardiac ventricle morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002084 ! heart left ventricle relationship: results_in_morphogenesis_of UBERON:0002084 ! heart left ventricle created_by: dph creation_date: 2009-10-13T09:50:08Z [Term] id: GO:0003215 name: cardiac right ventricle morphogenesis namespace: biological_process def: "The process in which the right cardiac ventricle is generated and organized." [GOC:mtg_heart] is_a: GO:0003208 ! cardiac ventricle morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002080 ! heart right ventricle relationship: results_in_morphogenesis_of UBERON:0002080 ! heart right ventricle created_by: dph creation_date: 2009-10-13T09:50:57Z [Term] id: GO:0003216 name: cardiac left atrium formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a left cardiac atrium from unspecified parts." [GOC:mtg_heart] is_a: GO:0003210 ! cardiac atrium formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0002079 ! left cardiac atrium relationship: part_of GO:0003212 ! cardiac left atrium morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0002079 ! left cardiac atrium created_by: dph creation_date: 2009-10-13T09:52:31Z [Term] id: GO:0003217 name: cardiac right atrium formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a cardiac right atrium from unspecified parts." [GOC:mtg_heart] is_a: GO:0003210 ! cardiac atrium formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0002078 ! right cardiac atrium relationship: part_of GO:0003213 ! cardiac right atrium morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0002078 ! right cardiac atrium created_by: dph creation_date: 2009-10-13T09:53:12Z [Term] id: GO:0003218 name: cardiac left ventricle formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a left cardiac ventricle from unspecified parts." [GOC:mtg_heart] is_a: GO:0003211 ! cardiac ventricle formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0002084 ! heart left ventricle relationship: part_of GO:0003214 ! cardiac left ventricle morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0002084 ! heart left ventricle created_by: dph creation_date: 2009-10-13T09:54:33Z [Term] id: GO:0003219 name: cardiac right ventricle formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a right cardiac ventricle from unspecified parts." [GOC:mtg_heart] is_a: GO:0003211 ! cardiac ventricle formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0002080 ! heart right ventricle relationship: part_of GO:0003215 ! cardiac right ventricle morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0002080 ! heart right ventricle created_by: dph creation_date: 2009-10-13T09:55:38Z [Term] id: GO:0003220 name: left ventricular cardiac muscle tissue morphogenesis namespace: biological_process def: "The process in which the anatomical structures of left cardiac ventricle muscle are generated and organized." [GOC:mtg_heart] synonym: "left ventricular myocardium morphogenesis" EXACT [GOC:mtg_heart] is_a: GO:0055010 ! ventricular cardiac muscle tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003382 ! cardiac muscle of left ventricle relationship: part_of GO:0003214 ! cardiac left ventricle morphogenesis relationship: results_in_morphogenesis_of UBERON:0003382 ! cardiac muscle of left ventricle created_by: dph creation_date: 2009-10-13T10:18:05Z [Term] id: GO:0003221 name: right ventricular cardiac muscle tissue morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the right cardiac ventricle muscle are generated and organized." [GOC:mtg_heart] synonym: "right ventricle myocardium morphogenesis" EXACT [GOC:mtg_heart] is_a: GO:0055010 ! ventricular cardiac muscle tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003381 ! cardiac muscle of right ventricle relationship: part_of GO:0003215 ! cardiac right ventricle morphogenesis relationship: results_in_morphogenesis_of UBERON:0003381 ! cardiac muscle of right ventricle created_by: dph creation_date: 2009-10-13T10:26:33Z [Term] id: GO:0003222 name: ventricular trabecula myocardium morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the trabecular cardiac ventricle muscle are generated and organized." [GOC:mtg_heart] synonym: "trabecula carnea morphogenesis" RELATED [GOC:dph] is_a: GO:0055010 ! ventricular cardiac muscle tissue morphogenesis is_a: GO:0061384 ! heart trabecula morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0004126 ! trabecular layer of ventricle relationship: results_in_morphogenesis_of UBERON:0004126 ! trabecular layer of ventricle created_by: dph creation_date: 2009-10-13T10:33:00Z [Term] id: GO:0003225 name: left ventricular trabecular myocardium morphogenesis namespace: biological_process def: "The process in which the anatomical structures of cardiac left ventricular trabecular myocardium are generated and organized." [GOC:mtg_heart] is_a: GO:0003220 ! left ventricular cardiac muscle tissue morphogenesis is_a: GO:0003222 ! ventricular trabecula myocardium morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0005064 ! left ventricular trabecular myocardium relationship: results_in_morphogenesis_of UBERON:0005064 ! left ventricular trabecular myocardium created_by: dph creation_date: 2009-10-13T10:45:09Z [Term] id: GO:0003227 name: right ventricular trabecular myocardium morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the right ventricular myocardium are generated and organized." [GOC:mtg_heart] is_a: GO:0003221 ! right ventricular cardiac muscle tissue morphogenesis is_a: GO:0003222 ! ventricular trabecula myocardium morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0005066 ! right ventricular trabecular myocardium relationship: results_in_morphogenesis_of UBERON:0005066 ! right ventricular trabecular myocardium created_by: dph creation_date: 2009-10-13T10:50:59Z [Term] id: GO:0003228 name: atrial cardiac muscle tissue development namespace: biological_process def: "The process whose specific outcome is the progression of cardiac muscle of the atrium over time, from its formation to the mature structure." [GOC:mtg_heart] synonym: "atrial myocardium development" EXACT [GOC:mtg_heart] is_a: GO:0048738 ! cardiac muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004490 ! cardiac muscle tissue of atrium relationship: results_in_development_of UBERON:0004490 ! cardiac muscle tissue of atrium property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22614" xsd:anyURI created_by: dph creation_date: 2009-10-13T10:53:18Z [Term] id: GO:0003229 name: ventricular cardiac muscle tissue development namespace: biological_process def: "The process whose specific outcome is the progression of ventricular cardiac muscle over time, from its formation to the mature structure." [GOC:mtg_heart] synonym: "ventricular myocardium development" EXACT [GOC:mtg_heart] is_a: GO:0048738 ! cardiac muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0018649 ! cardiac muscle tissue of ventricle relationship: results_in_development_of UBERON:0018649 ! cardiac muscle tissue of ventricle created_by: dph creation_date: 2009-10-13T10:56:01Z [Term] id: GO:0003230 name: cardiac atrium development namespace: biological_process def: "The process whose specific outcome is the progression of a cardiac atrium over time, from its formation to the mature structure. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle." [GOC:mtg_heart] is_a: GO:0003205 ! cardiac chamber development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002081 ! cardiac atrium relationship: results_in_development_of UBERON:0002081 ! cardiac atrium created_by: dph creation_date: 2009-10-13T11:02:07Z [Term] id: GO:0003231 name: cardiac ventricle development namespace: biological_process def: "The process whose specific outcome is the progression of a cardiac ventricle over time, from its formation to the mature structure. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart." [GOC:mtg_heart] is_a: GO:0003205 ! cardiac chamber development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002082 ! cardiac ventricle relationship: results_in_development_of UBERON:0002082 ! cardiac ventricle created_by: dph creation_date: 2009-10-13T11:03:16Z [Term] id: GO:0003235 name: sinus venosus development namespace: biological_process def: "The progression of the sinus venosus over time, from its formation to the mature structure. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart." [GOC:mtg_heart] is_a: GO:0003205 ! cardiac chamber development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002063 ! sinus venosus relationship: results_in_development_of UBERON:0002063 ! sinus venosus created_by: dph creation_date: 2009-10-13T11:12:34Z [Term] id: GO:0003236 name: sinus venosus morphogenesis namespace: biological_process def: "The process in which the sinus venosus is generated and organized. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart." [GOC:mtg_heart] is_a: GO:0003206 ! cardiac chamber morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002063 ! sinus venosus relationship: part_of GO:0003235 ! sinus venosus development relationship: results_in_morphogenesis_of UBERON:0002063 ! sinus venosus created_by: dph creation_date: 2009-10-13T11:16:52Z [Term] id: GO:0003237 name: sinus venosus formation namespace: biological_process def: "The developmental process pertaining to the initial formation of the sinus venosus from unspecified parts. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart." [GOC:mtg_heart] is_a: GO:0003207 ! cardiac chamber formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0002063 ! sinus venosus relationship: part_of GO:0003236 ! sinus venosus morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0002063 ! sinus venosus created_by: dph creation_date: 2009-10-13T11:18:34Z [Term] id: GO:0003238 name: conus arteriosus development namespace: biological_process def: "The progression of the conus arteriosus over time, from its formation to the mature structure. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk." [GOC:mtg_heart] is_a: GO:0003205 ! cardiac chamber development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003983 ! conus arteriosus relationship: results_in_development_of UBERON:0003983 ! conus arteriosus created_by: dph creation_date: 2009-10-13T11:20:57Z [Term] id: GO:0003239 name: conus arteriosus morphogenesis namespace: biological_process def: "The process in which the conus arteriosus is generated and organized. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk." [GOC:mtg_heart] is_a: GO:0003206 ! cardiac chamber morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003983 ! conus arteriosus relationship: part_of GO:0003238 ! conus arteriosus development relationship: results_in_morphogenesis_of UBERON:0003983 ! conus arteriosus created_by: dph creation_date: 2009-10-13T11:25:04Z [Term] id: GO:0003240 name: conus arteriosus formation namespace: biological_process def: "The developmental process pertaining to the initial formation of the conus arteriosus from unspecified parts. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk." [GOC:mtg_heart] is_a: GO:0003207 ! cardiac chamber formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0003983 ! conus arteriosus relationship: part_of GO:0003239 ! conus arteriosus morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0003983 ! conus arteriosus created_by: dph creation_date: 2009-10-13T11:25:47Z [Term] id: GO:0003241 name: growth involved in heart morphogenesis namespace: biological_process def: "Developmental growth that contributes to the shaping of the heart." [GOC:mtg_heart] is_a: GO:0060560 ! developmental growth involved in morphogenesis intersection_of: GO:0040007 ! growth intersection_of: part_of GO:0003007 ! heart morphogenesis relationship: part_of GO:0003007 ! heart morphogenesis relationship: part_of GO:0060419 ! heart growth created_by: dph creation_date: 2009-10-13T11:28:46Z [Term] id: GO:0003245 name: cardiac muscle tissue growth involved in heart morphogenesis namespace: biological_process def: "The developmental growth of cardiac muscle tissue that contributes to the shaping of the heart." [GOC:mtg_heart] is_a: GO:0003241 ! growth involved in heart morphogenesis is_a: GO:0055017 ! cardiac muscle tissue growth intersection_of: GO:0055017 ! cardiac muscle tissue growth intersection_of: part_of GO:0003007 ! heart morphogenesis relationship: part_of GO:0055008 ! cardiac muscle tissue morphogenesis created_by: dph creation_date: 2009-10-13T11:44:21Z [Term] id: GO:0003248 name: heart capillary growth namespace: biological_process def: "The increase in heart capillaries that accompanies physiological hypertrophy of cardiac muscle." [GOC:mtg_heart] is_a: GO:0048589 ! developmental growth intersection_of: GO:0048589 ! developmental growth intersection_of: results_in_growth_of UBERON:0006966 ! coronary capillary relationship: part_of GO:0060419 ! heart growth relationship: part_of GO:0060976 ! coronary vasculature development relationship: results_in_growth_of UBERON:0006966 ! coronary capillary created_by: dph creation_date: 2009-10-13T11:53:12Z [Term] id: GO:0003253 name: cardiac neural crest cell migration involved in outflow tract morphogenesis namespace: biological_process def: "The orderly movement of a neural crest cell from one site to another that will contribute to the morphogenesis of the outflow tract." [GOC:mtg_heart] is_a: GO:0001755 ! neural crest cell migration is_a: GO:0060973 ! cell migration involved in heart development intersection_of: GO:0001755 ! neural crest cell migration intersection_of: part_of GO:0003151 ! outflow tract morphogenesis relationship: part_of GO:0061309 ! cardiac neural crest cell development involved in outflow tract morphogenesis created_by: dph creation_date: 2009-10-13T02:14:16Z [Term] id: GO:0003260 name: cardioblast migration namespace: biological_process def: "The orderly movement of a cardiac progenitor cell to form the heart field. Cardiac progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into cells of the heart. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:mtg_heart] is_a: GO:0060974 ! cell migration involved in heart formation intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0002664 ! cardioblast relationship: results_in_movement_of CL:0002664 ! cardioblast created_by: dph creation_date: 2009-10-15T01:52:25Z [Term] id: GO:0003272 name: endocardial cushion formation namespace: biological_process def: "The developmental process pertaining to the initial formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves." [GOC:mtg_heart, PMID:15797462] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0002062 ! endocardial cushion relationship: part_of GO:0003203 ! endocardial cushion morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0002062 ! endocardial cushion created_by: dph creation_date: 2009-10-20T08:53:19Z [Term] id: GO:0003273 name: cell migration involved in endocardial cushion formation namespace: biological_process def: "The orderly movement of a cell from one site to another that will contribute to the formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves." [GOC:mtg_heart] is_a: GO:0060973 ! cell migration involved in heart development intersection_of: GO:0016477 ! cell migration intersection_of: part_of GO:0003272 ! endocardial cushion formation relationship: part_of GO:0003272 ! endocardial cushion formation created_by: dph creation_date: 2009-10-20T09:08:44Z [Term] id: GO:0003275 name: apoptotic process involved in outflow tract morphogenesis namespace: biological_process def: "Any apoptotic process that contributes to the shaping of the outflow tract. The outflow tract is the portion of the heart through which blood flows into the arteries." [GOC:mtg_apoptosis, GOC:mtg_heart] synonym: "apoptosis involved in outflow tract morphogenesis" NARROW [] is_a: GO:0003278 ! apoptotic process involved in heart morphogenesis intersection_of: GO:0006915 ! apoptotic process intersection_of: part_of GO:0003151 ! outflow tract morphogenesis relationship: part_of GO:0003151 ! outflow tract morphogenesis created_by: dph creation_date: 2009-10-20T09:30:01Z [Term] id: GO:0003277 name: apoptotic process involved in endocardial cushion morphogenesis namespace: biological_process def: "Any apoptotic process that contributes to the shaping of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves." [GOC:mtg_apoptosis, GOC:mtg_heart] synonym: "apoptosis involved in endocardial cushion morphogenesis" NARROW [] is_a: GO:0003278 ! apoptotic process involved in heart morphogenesis intersection_of: GO:0006915 ! apoptotic process intersection_of: part_of GO:0003203 ! endocardial cushion morphogenesis relationship: part_of GO:0003203 ! endocardial cushion morphogenesis created_by: dph creation_date: 2009-10-20T09:37:03Z [Term] id: GO:0003278 name: apoptotic process involved in heart morphogenesis namespace: biological_process def: "Any apoptotic process that contributes to the shaping of the heart." [GOC:mtg_apoptosis, GOC:mtg_heart] synonym: "apoptosis involved in heart morphogenesis" NARROW [] is_a: GO:0060561 ! apoptotic process involved in morphogenesis intersection_of: GO:0006915 ! apoptotic process intersection_of: part_of GO:0003007 ! heart morphogenesis relationship: part_of GO:0003007 ! heart morphogenesis created_by: dph creation_date: 2009-10-20T09:40:22Z [Term] id: GO:0003279 name: cardiac septum development namespace: biological_process def: "The progression of a cardiac septum over time, from its initial formation to the mature structure." [GOC:mtg_heart] synonym: "heart septum development" EXACT [GOC:mtg_heart] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002099 ! cardiac septum relationship: part_of GO:0003205 ! cardiac chamber development relationship: results_in_development_of UBERON:0002099 ! cardiac septum created_by: dph creation_date: 2009-10-20T09:45:13Z [Term] id: GO:0003281 name: ventricular septum development namespace: biological_process def: "The progression of the ventricular septum over time from its formation to the mature structure." [GOC:mtg_heart] synonym: "interventricular septum development" EXACT [GOC:mtg_heart] synonym: "septum inferius development" NARROW [GOC:mtg_heart] is_a: GO:0003279 ! cardiac septum development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002094 ! interventricular septum relationship: part_of GO:0003231 ! cardiac ventricle development relationship: results_in_development_of UBERON:0002094 ! interventricular septum created_by: dph creation_date: 2009-10-20T10:04:51Z [Term] id: GO:0003283 name: atrial septum development namespace: biological_process def: "The progression of the atrial septum over time, from its initial formation to the mature structure." [GOC:mtg_heart] is_a: GO:0003279 ! cardiac septum development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002085 ! interatrial septum relationship: part_of GO:0003230 ! cardiac atrium development relationship: results_in_development_of UBERON:0002085 ! interatrial septum created_by: dph creation_date: 2009-10-20T10:10:38Z [Term] id: GO:0003292 name: cardiac septum cell differentiation namespace: biological_process def: "The process in which an endocardial cushion cell becomes a cell of a cardiac septum." [GOC:mtg_heart] is_a: GO:0035051 ! cardiocyte differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:2000022 ! cardiac septum cell relationship: part_of GO:0003279 ! cardiac septum development relationship: results_in_acquisition_of_features_of CL:2000022 ! cardiac septum cell created_by: dph creation_date: 2009-10-20T11:03:46Z [Term] id: GO:0003298 name: physiological muscle hypertrophy namespace: biological_process def: "The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development." [GOC:mtg_heart] is_a: GO:0014896 ! muscle hypertrophy created_by: dph creation_date: 2009-10-22T09:24:51Z [Term] id: GO:0003300 name: cardiac muscle hypertrophy namespace: biological_process def: "The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division." [GOC:mtg_heart] is_a: GO:0014897 ! striated muscle hypertrophy created_by: dph creation_date: 2009-10-22T10:33:56Z [Term] id: GO:0003301 name: physiological cardiac muscle hypertrophy namespace: biological_process def: "The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division. This process contributes to the developmental growth of the heart." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:mtg_heart] is_a: GO:0003298 ! physiological muscle hypertrophy is_a: GO:0003300 ! cardiac muscle hypertrophy relationship: part_of GO:0055017 ! cardiac muscle tissue growth created_by: dph creation_date: 2009-10-22T10:38:10Z [Term] id: GO:0003309 name: type B pancreatic cell differentiation namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features of a type B pancreatic cell. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin." [CL:0000169, GOC:dph, PMID:11076772] synonym: "pancreatic B cell differentiation" EXACT [GOC:mah] synonym: "pancreatic beta cell differentiation" EXACT [GOC:dph] is_a: GO:0035883 ! enteroendocrine cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000169 ! type B pancreatic cell relationship: part_of GO:0031018 ! endocrine pancreas development relationship: results_in_acquisition_of_features_of CL:0000169 ! type B pancreatic cell created_by: dph creation_date: 2009-10-26T09:27:23Z [Term] id: GO:0003310 name: pancreatic A cell differentiation namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic A cell. A pancreatic A cell is a cell in the pancreas that secretes glucagon." [GOC:dph, PMID:11076772] synonym: "pancreatic alpha cell differentiation" EXACT [GOC:dph] is_a: GO:0035883 ! enteroendocrine cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000171 ! pancreatic A cell relationship: part_of GO:0031018 ! endocrine pancreas development relationship: results_in_acquisition_of_features_of CL:0000171 ! pancreatic A cell created_by: dph creation_date: 2009-10-26T09:28:05Z [Term] id: GO:0003311 name: pancreatic D cell differentiation namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and functional features that characterize a pancreatic delta cell. A delta cell is a cell of the pancreas that produces somatostatin." [GOC:dph, PMID:11076772] synonym: "pancreatic delta cell differentiation" EXACT [GOC:dph] is_a: GO:0035883 ! enteroendocrine cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000173 ! pancreatic D cell relationship: part_of GO:0031018 ! endocrine pancreas development relationship: results_in_acquisition_of_features_of CL:0000173 ! pancreatic D cell created_by: dph creation_date: 2009-10-26T09:30:27Z [Term] id: GO:0003312 name: pancreatic PP cell differentiation namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic polypeptide-producing cell. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide." [GOC:dph, PMID:11076772] synonym: "pancreatic polypeptide-producing cell differentiation" EXACT [GOC:dph] is_a: GO:0035883 ! enteroendocrine cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0002275 ! pancreatic PP cell relationship: part_of GO:0031018 ! endocrine pancreas development relationship: results_in_acquisition_of_features_of CL:0002275 ! pancreatic PP cell created_by: dph creation_date: 2009-10-26T09:32:32Z [Term] id: GO:0003313 name: heart rudiment development namespace: biological_process def: "The progression of the heart rudiment over time, from its initial formation to the mature structure. The heart rudiment is a cone-like structure that is formed when myocardial progenitor cells of the heart field fuse at the midline. The heart rudiment is the first structure of the heart tube." [GOC:mtg_heart] synonym: "heart cone development" EXACT [GOC:mtg_heart] is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004291 ! heart rudiment relationship: part_of GO:0035050 ! embryonic heart tube development relationship: results_in_development_of UBERON:0004291 ! heart rudiment created_by: dph creation_date: 2009-10-27T08:32:40Z [Term] id: GO:0003314 name: heart rudiment morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the heart rudiment are generated and organized." [GOC:mtg_heart] synonym: "heart cone morphogenesis" EXACT [GOC:mtg_heart] is_a: GO:0002009 ! morphogenesis of an epithelium is_a: GO:0048598 ! embryonic morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0004291 ! heart rudiment relationship: part_of GO:0003313 ! heart rudiment development relationship: results_in_morphogenesis_of UBERON:0004291 ! heart rudiment created_by: dph creation_date: 2009-10-27T08:38:04Z [Term] id: GO:0003315 name: heart rudiment formation namespace: biological_process def: "The developmental process pertaining to the initial formation of the heart rudiment." [GOC:mtg_heart] synonym: "heart cone formation" EXACT [GOC:mtg_heart] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0004291 ! heart rudiment relationship: part_of GO:0003314 ! heart rudiment morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0004291 ! heart rudiment created_by: dph creation_date: 2009-10-27T08:43:37Z [Term] id: GO:0003322 name: pancreatic A cell development namespace: biological_process def: "The process whose specific outcome is the progression of a pancreatic A cell over time, from its formation to the mature structure. A pancreatic A cell is a cell in the pancreas that secretes glucagon." [GOC:dph] synonym: "pancreatic alpha cell development" EXACT [GOC:dph] is_a: GO:0002068 ! glandular epithelial cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000171 ! pancreatic A cell relationship: part_of GO:0003310 ! pancreatic A cell differentiation relationship: results_in_development_of CL:0000171 ! pancreatic A cell created_by: dph creation_date: 2009-11-02T08:13:55Z [Term] id: GO:0003323 name: type B pancreatic cell development namespace: biological_process def: "The process whose specific outcome is the progression of a type B pancreatic cell over time, from its formation to the mature structure. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin." [CL:0000169, GOC:dph] synonym: "pancreatic B cell development" EXACT [GOC:mah] synonym: "pancreatic beta cell development" EXACT [GOC:dph] is_a: GO:0002068 ! glandular epithelial cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000169 ! type B pancreatic cell relationship: part_of GO:0003309 ! type B pancreatic cell differentiation relationship: results_in_development_of CL:0000169 ! type B pancreatic cell created_by: dph creation_date: 2009-11-02T08:20:11Z [Term] id: GO:0003324 name: pancreatic D cell development namespace: biological_process def: "The process whose specific outcome is the progression of a pancreatic delta cell over time, from its formation to the mature structure. A delta cell is a cell of the pancreas that produces somatostatin." [GOC:dph] synonym: "pancreatic delta cell development" EXACT [GOC:dph] is_a: GO:0002068 ! glandular epithelial cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000173 ! pancreatic D cell relationship: part_of GO:0003311 ! pancreatic D cell differentiation relationship: results_in_development_of CL:0000173 ! pancreatic D cell created_by: dph creation_date: 2009-11-02T08:23:26Z [Term] id: GO:0003325 name: pancreatic PP cell development namespace: biological_process def: "The process whose specific outcome is the progression of a pancreatic PP cell over time, from its formation to the mature structure. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide." [GOC:dph] is_a: GO:0002068 ! glandular epithelial cell development intersection_of: GO:0048468 ! cell development intersection_of: results_in_development_of CL:0002275 ! pancreatic PP cell relationship: part_of GO:0003312 ! pancreatic PP cell differentiation relationship: results_in_development_of CL:0002275 ! pancreatic PP cell created_by: dph creation_date: 2009-11-02T08:25:03Z [Term] id: GO:0003333 name: amino acid transmembrane transport namespace: biological_process def: "The process in which an amino acid is transported across a membrane." [GOC:dph, GOC:tb] comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "amino acid membrane transport" EXACT [] is_a: GO:0006865 ! amino acid transport is_a: GO:1903825 ! organic acid transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:33709 ! amino acid intersection_of: results_in_transport_across GO:0016020 ! membrane created_by: dph creation_date: 2009-11-02T02:36:11Z [Term] id: GO:0003337 name: mesenchymal to epithelial transition involved in metanephros morphogenesis namespace: biological_process def: "A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros." [GOC:dph, GOC:yaf] synonym: "metanephric mesenchyme to epithelial transition" RELATED [GOC:dph] is_a: GO:0035850 ! epithelial cell differentiation involved in kidney development is_a: GO:0060231 ! mesenchymal to epithelial transition is_a: GO:0072202 ! cell differentiation involved in metanephros development intersection_of: GO:0060231 ! mesenchymal to epithelial transition intersection_of: part_of GO:0003338 ! metanephros morphogenesis relationship: part_of GO:0072283 ! metanephric renal vesicle morphogenesis created_by: dph creation_date: 2009-11-24T09:29:49Z [Term] id: GO:0003338 name: metanephros morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the metanephros are generated and organized." [GOC:dph, GOC:yaf] is_a: GO:0060993 ! kidney morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000081 ! metanephros relationship: part_of GO:0001656 ! metanephros development relationship: results_in_morphogenesis_of UBERON:0000081 ! metanephros created_by: dph creation_date: 2009-11-24T09:32:09Z [Term] id: GO:0003339 name: regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis namespace: biological_process def: "Any process that modulates the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros." [GOC:dph] is_a: GO:2000696 ! regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003337 ! mesenchymal to epithelial transition involved in metanephros morphogenesis relationship: regulates GO:0003337 ! mesenchymal to epithelial transition involved in metanephros morphogenesis created_by: dph creation_date: 2009-11-24T09:43:04Z [Term] id: GO:0003340 name: negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis namespace: biological_process def: "Any process that decreases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros." [GOC:dph, GOC:yaf] is_a: GO:0003339 ! regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis is_a: GO:2000697 ! negative regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0003337 ! mesenchymal to epithelial transition involved in metanephros morphogenesis relationship: negatively_regulates GO:0003337 ! mesenchymal to epithelial transition involved in metanephros morphogenesis created_by: dph creation_date: 2009-11-24T09:46:12Z [Term] id: GO:0003341 name: cilium movement namespace: biological_process alt_id: GO:0036142 def: "The directed, self-propelled movement of a cilium." [GOC:dph, GOC:jl] comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. synonym: "ciliary motility" RELATED [] synonym: "cilium beating" RELATED [GOC:ascb_2009, GOC:dph, GOC:tb] synonym: "flagellar motility" RELATED [] synonym: "flagellar movement" NARROW [GOC:bf] synonym: "flagellum movement" NARROW [] synonym: "microtubule-based flagellum movement" EXACT [] is_a: GO:0007018 ! microtubule-based movement intersection_of: GO:0007018 ! microtubule-based movement intersection_of: process_has_causal_agent GO:0005874 ! microtubule intersection_of: results_in_movement_of GO:0005929 ! cilium relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota relationship: results_in_movement_of GO:0005929 ! cilium property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19809" xsd:anyURI property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3312 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4890 property_value: RO:0002161 NCBITaxon:5782 created_by: dph creation_date: 2009-11-24T09:56:26Z [Term] id: GO:0003342 name: proepicardium development namespace: biological_process def: "The progression of the proepicardium from its formation to the mature structure. The proepicardium is an outpouching of the septum transversum." [GOC:dph, PMID:18722343] is_a: GO:0060485 ! mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004160 ! proepicardium relationship: part_of GO:0003343 ! septum transversum development relationship: results_in_development_of UBERON:0004160 ! proepicardium created_by: dph creation_date: 2009-12-01T10:30:17Z [Term] id: GO:0003343 name: septum transversum development namespace: biological_process def: "The progression of the septum transversum from its initial formation to the mature structure. The septum transversum is a portion of the trunk mesenchyme." [GOC:dph, PMID:18722343] is_a: GO:0060485 ! mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004161 ! septum transversum relationship: results_in_development_of UBERON:0004161 ! septum transversum created_by: dph creation_date: 2009-12-01T10:40:17Z [Term] id: GO:0003344 name: pericardium morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the pericardium is generated and organized." [GOC:dph, PMID:18722343] is_a: GO:0002011 ! morphogenesis of an epithelial sheet is_a: GO:0048598 ! embryonic morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002407 ! pericardium relationship: part_of GO:0060039 ! pericardium development relationship: results_in_morphogenesis_of UBERON:0002407 ! pericardium created_by: dph creation_date: 2009-12-01T10:46:34Z [Term] id: GO:0003348 name: cardiac endothelial cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac endothelial cell." [GOC:dph, PMID:18722343] is_a: GO:0035051 ! cardiocyte differentiation is_a: GO:0045446 ! endothelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0010008 ! cardiac endothelial cell relationship: results_in_acquisition_of_features_of CL:0010008 ! cardiac endothelial cell created_by: dph creation_date: 2009-12-01T11:12:05Z [Term] id: GO:0003352 name: regulation of cilium movement namespace: biological_process alt_id: GO:1900172 def: "Any process that modulates the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium." [GOC:dph] comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. synonym: "regulation of flagellar movement" RELATED [GOC:TermGenie] synonym: "regulation of flagellum movement" RELATED [] synonym: "regulation of microtubule-based flagellum movement" EXACT [] is_a: GO:0060632 ! regulation of microtubule-based movement intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003341 ! cilium movement relationship: regulates GO:0003341 ! cilium movement created_by: dph creation_date: 2009-12-03T10:12:00Z [Term] id: GO:0003353 name: positive regulation of cilium movement namespace: biological_process alt_id: GO:1900174 def: "Any process that increases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium." [GOC:dph] comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. synonym: "positive regulation of flagellar movement" RELATED [GOC:TermGenie] synonym: "positive regulation of flagellum movement" RELATED [] synonym: "positive regulation of microtubule-based flagellum movement" EXACT [] is_a: GO:0003352 ! regulation of cilium movement is_a: GO:0048522 ! positive regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0003341 ! cilium movement relationship: positively_regulates GO:0003341 ! cilium movement created_by: dph creation_date: 2009-12-03T10:16:10Z [Term] id: GO:0003354 name: negative regulation of cilium movement namespace: biological_process alt_id: GO:1900173 def: "Any process that decreases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium." [GOC:dph] comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. synonym: "negative regulation of flagellum movement" RELATED [] synonym: "negative regulation of microtubule-based flagellum movement" EXACT [] is_a: GO:0003352 ! regulation of cilium movement is_a: GO:0048523 ! negative regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0003341 ! cilium movement relationship: negatively_regulates GO:0003341 ! cilium movement created_by: dph creation_date: 2009-12-03T10:17:47Z [Term] id: GO:0003357 name: noradrenergic neuron differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron, a neuron that secretes noradrenaline." [GOC:dph] synonym: "norepinephrine secreting neuron differentiation" EXACT [GOC:dph] is_a: GO:0030182 ! neuron differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0008025 ! noradrenergic neuron relationship: results_in_acquisition_of_features_of CL:0008025 ! noradrenergic neuron created_by: dph creation_date: 2009-12-03T10:34:30Z [Term] id: GO:0003358 name: noradrenergic neuron development namespace: biological_process def: "The process whose specific outcome is the progression of a noradrenergic neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:dph] synonym: "norepinephrine secreting neuron development" EXACT [GOC:dph] is_a: GO:0048666 ! neuron development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0008025 ! noradrenergic neuron relationship: part_of GO:0003357 ! noradrenergic neuron differentiation relationship: results_in_development_of CL:0008025 ! noradrenergic neuron created_by: dph creation_date: 2009-12-03T10:38:37Z [Term] id: GO:0003360 name: brainstem development namespace: biological_process def: "The progression of the brainstem from its formation to the mature structure. The brainstem is the part of the brain that connects the brain with the spinal cord." [GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002298 ! brainstem relationship: results_in_development_of UBERON:0002298 ! brainstem created_by: dph creation_date: 2009-12-03T10:47:20Z [Term] id: GO:0003361 name: noradrenergic neuron differentiation involved in brainstem development namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron that is part of the brainstem." [GOC:dph] is_a: GO:0003357 ! noradrenergic neuron differentiation intersection_of: GO:0003357 ! noradrenergic neuron differentiation intersection_of: part_of GO:0003360 ! brainstem development relationship: part_of GO:0003360 ! brainstem development created_by: dph creation_date: 2009-12-03T10:53:30Z [Term] id: GO:0003365 name: establishment of cell polarity involved in ameboidal cell migration namespace: biological_process def: "The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0030010 ! establishment of cell polarity intersection_of: GO:0030010 ! establishment of cell polarity intersection_of: part_of GO:0001667 ! ameboidal-type cell migration relationship: part_of GO:0001667 ! ameboidal-type cell migration property_value: RO:0002161 NCBITaxon:4751 created_by: dph creation_date: 2009-12-08T04:50:41Z [Term] id: GO:0003371 name: establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration namespace: biological_process def: "Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0030952 ! establishment or maintenance of cytoskeleton polarity intersection_of: GO:0030952 ! establishment or maintenance of cytoskeleton polarity intersection_of: part_of GO:0001667 ! ameboidal-type cell migration relationship: part_of GO:0003365 ! establishment of cell polarity involved in ameboidal cell migration created_by: dph creation_date: 2009-12-08T05:42:46Z [Term] id: GO:0003379 name: establishment of cell polarity involved in gastrulation cell migration namespace: biological_process def: "The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell taking part in gastrulation." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0003365 ! establishment of cell polarity involved in ameboidal cell migration intersection_of: GO:0030010 ! establishment of cell polarity intersection_of: part_of GO:0042074 ! cell migration involved in gastrulation relationship: part_of GO:0042074 ! cell migration involved in gastrulation created_by: dph creation_date: 2009-12-09T06:54:44Z [Term] id: GO:0003380 name: establishment or maintenance of cytoskeleton polarity involved in gastrulation namespace: biological_process def: "Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell taking part in gastrulation." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0003371 ! establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration intersection_of: GO:0030952 ! establishment or maintenance of cytoskeleton polarity intersection_of: part_of GO:0007369 ! gastrulation relationship: part_of GO:0003379 ! establishment of cell polarity involved in gastrulation cell migration created_by: dph creation_date: 2009-12-09T07:10:57Z [Term] id: GO:0003381 name: epithelial cell morphogenesis involved in gastrulation namespace: biological_process def: "The change in form that occurs when an epithelial cell progresses from it initial formation to its mature state, contributing to the process of gastrulation." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0003382 ! epithelial cell morphogenesis intersection_of: GO:0003382 ! epithelial cell morphogenesis intersection_of: part_of GO:0007369 ! gastrulation relationship: part_of GO:0007369 ! gastrulation created_by: dph creation_date: 2009-12-09T07:18:53Z [Term] id: GO:0003382 name: epithelial cell morphogenesis namespace: biological_process def: "The change in form that occurs when an epithelial cell progresses from its initial formation to its mature state." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0000902 ! cell morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_maturation_of CL:0000066 ! epithelial cell relationship: part_of GO:0002064 ! epithelial cell development relationship: results_in_maturation_of CL:0000066 ! epithelial cell created_by: dph creation_date: 2009-12-09T07:21:06Z [Term] id: GO:0003403 name: optic vesicle formation namespace: biological_process def: "The developmental process pertaining to the initial formation of the optic vesicle from the lateral wall of the forebrain. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0004128 ! optic vesicle relationship: part_of GO:0003404 ! optic vesicle morphogenesis relationship: part_of GO:0060900 ! embryonic camera-type eye formation relationship: results_in_formation_of_anatomical_entity UBERON:0004128 ! optic vesicle created_by: dph creation_date: 2009-12-21T01:42:37Z [Term] id: GO:0003404 name: optic vesicle morphogenesis namespace: biological_process def: "The developmental process pertaining to the formation and shaping of the optic vesicle. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0048598 ! embryonic morphogenesis is_a: GO:0048729 ! tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0004128 ! optic vesicle relationship: part_of GO:0048596 ! embryonic camera-type eye morphogenesis relationship: results_in_morphogenesis_of UBERON:0004128 ! optic vesicle created_by: dph creation_date: 2009-12-21T01:54:34Z [Term] id: GO:0003407 name: neural retina development namespace: biological_process def: "The progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003902 ! retinal neural layer relationship: part_of GO:0060041 ! retina development in camera-type eye relationship: results_in_development_of UBERON:0003902 ! retinal neural layer created_by: dph creation_date: 2009-12-21T02:15:14Z [Term] id: GO:0003411 name: cell motility involved in camera-type eye morphogenesis namespace: biological_process def: "Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another and contributes to the physical shaping or formation of the camera-type eye." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0048870 ! cell motility intersection_of: GO:0048870 ! cell motility intersection_of: part_of GO:0048593 ! camera-type eye morphogenesis relationship: part_of GO:0048593 ! camera-type eye morphogenesis created_by: dph creation_date: 2009-12-21T03:04:27Z [Term] id: GO:0003413 name: chondrocyte differentiation involved in endochondral bone morphogenesis namespace: biological_process def: "The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0002062 ! chondrocyte differentiation intersection_of: GO:0002062 ! chondrocyte differentiation intersection_of: part_of GO:0060350 ! endochondral bone morphogenesis relationship: part_of GO:0060351 ! cartilage development involved in endochondral bone morphogenesis created_by: dph creation_date: 2009-12-22T08:39:58Z [Term] id: GO:0003414 name: chondrocyte morphogenesis involved in endochondral bone morphogenesis namespace: biological_process def: "The process in which the structures of a chondrocyte that will contribute to bone development are generated and organized." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0090171 ! chondrocyte morphogenesis intersection_of: GO:0090171 ! chondrocyte morphogenesis intersection_of: part_of GO:0060350 ! endochondral bone morphogenesis relationship: part_of GO:0003433 ! chondrocyte development involved in endochondral bone morphogenesis created_by: dph creation_date: 2009-12-22T08:42:55Z [Term] id: GO:0003416 name: endochondral bone growth namespace: biological_process def: "The increase in size or mass of an endochondral bone that contributes to the shaping of the bone." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0098868 ! bone growth intersection_of: GO:0048589 ! developmental growth intersection_of: results_in_growth_of UBERON:0002513 ! endochondral bone relationship: results_in_growth_of UBERON:0002513 ! endochondral bone created_by: dph creation_date: 2009-12-22T08:52:55Z [Term] id: GO:0003433 name: chondrocyte development involved in endochondral bone morphogenesis namespace: biological_process def: "The progression of a chondrocyte over time from after its commitment to its mature state where the chondrocyte will contribute to the shaping of an endochondral bone." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0002063 ! chondrocyte development intersection_of: GO:0002063 ! chondrocyte development intersection_of: part_of GO:0060350 ! endochondral bone morphogenesis relationship: part_of GO:0003413 ! chondrocyte differentiation involved in endochondral bone morphogenesis created_by: dph creation_date: 2009-12-22T12:42:44Z [Term] id: GO:0003674 name: gene product or complex activity name: molecular_function namespace: molecular_function alt_id: GO:0005554 def: "A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs." [GOC:pdt] def: "A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. These actions are described from two distinct but related perspectives: (1) biochemical activity, and (2) role as a component in a larger system/process." [GOC:pdt] comment: Note that, in addition to forming the root of the molecular function ontology, this term is recommended for the annotation of gene products whose molecular function is unknown. When this term is used for annotation, it indicates that no information was available about the molecular function of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. Despite its name, this is not a type of 'function' in the sense typically defined by upper ontologies such as Basic Formal Ontology (BFO). It is instead a BFO:process carried out by a single gene product or complex. comment: Note that, in addition to forming the root of the molecular function ontology, this term is recommended for use for the annotation of gene products whose molecular function is unknown. When this term is used for annotation, it indicates that no information was available about the molecular function of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. Despite its name, this is not a type of 'function' in the sense typically defined by upper ontologies such as Basic Formal Ontology (BFO). It is instead a BFO:process carried out by a single gene product or complex. subset: goslim_candida subset: goslim_chembl subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant subset: goslim_yeast synonym: "molecular function" EXACT [] is_a: BFO:0000015 ! process disjoint_from: GO:0005575 ! cellular_component disjoint_from: GO:0008150 ! biological process property_value: editor_note "This is the same as GO molecular function" xsd:string [Term] id: GO:0003824 name: catalytic activity namespace: molecular_function def: "Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic." [GOC:vw, ISBN:0198506732] subset: goslim_agr subset: goslim_chembl subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant synonym: "enzyme activity" EXACT [GOC:dph, GOC:tb] xref: Wikipedia:Enzyme is_a: GO:0003674 ! molecular_function [Term] id: GO:0004518 name: nuclease activity namespace: molecular_function def: "Catalysis of the hydrolysis of ester linkages within nucleic acids." [ISBN:0198547684] comment: Note that 'tRNA nucleotidyltransferase activity ; GO:0009022', also known as 'ribonuclease PH', and 'DNA-(apurinic or apyrimidinic site) lyase activity ; GO:0003906' do not have parentage in the 'nuclease activity' branch of the ontology because both GO and the Enzyme Commission define nuclease activity as a type of hydrolysis. subset: goslim_chembl subset: goslim_drosophila subset: goslim_plant subset: goslim_yeast is_a: GO:0016788 ! hydrolase activity, acting on ester bonds [Term] id: GO:0004536 name: DNA nuclease activity namespace: molecular_function alt_id: GO:0004537 def: "Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid." [GOC:mah, ISBN:0198547684] synonym: "caspase-activated deoxyribonuclease activity" NARROW [] synonym: "deoxyribonuclease activity" EXACT [] xref: Reactome:R-HSA-211247 "Cleavage of DNA by DFF40" xref: Reactome:R-HSA-5685994 "Long-range resection of DNA DSBs by EXO1 or DNA2" xref: Reactome:R-HSA-6785986 "DNA nucleases unhook the interstrand crosslink (ICL)" is_a: GO:0004518 ! nuclease activity is_a: GO:0140097 ! catalytic activity, acting on DNA relationship: part_of GO:0006259 ! DNA metabolic process [Term] id: GO:0005215 name: transporter activity namespace: molecular_function alt_id: GO:0005478 def: "Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells." [GOC:ai, GOC:dgf] comment: Some transporters, such as certain members of the SLC family, are referred to as 'carriers'; however GO uses carrier with a different meaning: a carrier binds to and transports the substance (see GO:0140104 molecular carrier activity), whereas a transporter forms some pore that allows the passing of molecules. subset: gocheck_do_not_annotate subset: goslim_agr subset: goslim_candida subset: goslim_chembl subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_metagenomics subset: goslim_mouse subset: goslim_pir subset: goslim_plant subset: goslim_prokaryote synonym: "carrier" RELATED [] xref: Reactome:R-HSA-168313 "Virion-associated M2 protein mediated ion infusion" xref: Reactome:R-HSA-178215 "SMAD7:SMURF1 complex is exported to the cytosol" is_a: GO:0003674 ! molecular_function [Term] id: GO:0005275 name: amine transmembrane transporter activity namespace: molecular_function alt_id: GO:0005279 def: "Enables the transfer of amines, including polyamines, from one side of a membrane to the other. Amines are organic compounds that are weakly basic in character and contain an amino (-NH2) or substituted amino group." [GOC:mtg_transport, ISBN:0198506732, ISBN:0815340729] synonym: "amine/amide/polyamine channel activity" BROAD [] synonym: "amine/polyamine transmembrane transporter activity" EXACT [] synonym: "amino acid-polyamine transmembrane transporter activity" EXACT [] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:32952 ! amine relationship: has_primary_input CHEBI:32952 ! amine relationship: part_of GO:0015837 ! amine transport [Term] id: GO:0005277 name: acetylcholine transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of acetylcholine from one side of a membrane to the other. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions." [GOC:ai] xref: Reactome:R-HSA-264615 "Loading of acetylcholine in synaptic vesicles" is_a: GO:0005326 ! neurotransmitter transmembrane transporter activity is_a: GO:0015101 ! organic cation transmembrane transporter activity is_a: GO:1901375 ! acetate ester transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:15355 ! acetylcholine relationship: has_primary_input CHEBI:15355 ! acetylcholine [Term] id: GO:0005310 name: dicarboxylic acid transmembrane transporter activity namespace: molecular_function alt_id: GO:0005312 alt_id: GO:0015365 def: "Enables the transfer of dicarboxylic acids from one side of a membrane to the other. A dicarboxylic acid is an organic acid with two COOH groups." [GOC:ai] synonym: "dicarboxylate (succinate/fumarate/malate) antiporter activity" RELATED [] synonym: "dicarboxylate carrier" NARROW [] synonym: "dicarboxylic acid permease activity" RELATED [] synonym: "sodium:dicarboxylate/tricarboxylate symporter activity" NARROW [] xref: Reactome:R-HSA-1614546 "Sulfate is exported to the cytosol in exchange for dicarboxylate" xref: Reactome:R-HSA-372843 "SLC25A10 mediates exchange of malate and phosphate" is_a: GO:0005342 ! organic acid transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:35692 ! dicarboxylic acid relationship: has_primary_input CHEBI:35692 ! dicarboxylic acid relationship: part_of GO:0006835 ! dicarboxylic acid transport [Term] id: GO:0005319 name: lipid transporter activity namespace: molecular_function def: "Enables the directed movement of lipids into, out of or within a cell, or between cells." [GOC:ai] synonym: "apolipoprotein" RELATED [] synonym: "lipophorin" NARROW [] xref: Reactome:R-HSA-1369028 "ABCAs mediate lipid efflux" xref: Reactome:R-HSA-1369052 "ABCAs mediate lipid influx" xref: Reactome:R-HSA-174786 "ApoB-48 + 40 triacylglycerol + 60 phospholipid => ApoB-48:TG:PL complex" xref: Reactome:R-HSA-5682285 "ABCA12 transports lipids from cytosol to extracellular region" xref: Reactome:R-HSA-5682311 "Defective ABCA12 does not transport lipids from cytosol to extracellular region" xref: Reactome:R-HSA-5683672 "Defective ABCA3 does not transport PC, PG from ER membrane to lamellar body" xref: Reactome:R-HSA-5683714 "ABCA3 transports PC, PG from ER membrane to lamellar body" xref: Reactome:R-HSA-5688397 "Defective ABCA3 does not transport PC, PG from ER membrane to lamellar body" xref: Reactome:R-HSA-6801250 "TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane" xref: Reactome:R-HSA-8848053 "ABCA5 transports CHOL from lysosomal lumen to cytosol" xref: Reactome:R-HSA-8866329 "MTTP lipidates APOB-100, forming a pre-VLDL" is_a: GO:0005215 ! transporter activity intersection_of: GO:0005215 ! transporter activity intersection_of: has_primary_input CHEBI:18059 ! lipid relationship: has_primary_input CHEBI:18059 ! lipid relationship: part_of GO:0006869 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! lipid transport [Term] id: GO:0005326 name: neurotransmitter transmembrane transporter activity namespace: molecular_function def: "Enables the directed movement of a neurotransmitter into, out of or within a cell, or between cells. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell." [GOC:ai, ISBN:0198506732] synonym: "neurotransmitter transporter activity" RELATED [] xref: Reactome:R-HSA-374896 "Uptake of Noradrenaline" xref: Reactome:R-HSA-374919 "Noradrenaline clearance from the synaptic cleft" relationship: in_taxon NCBITaxon:6072 {all_only="true"} ! Eumetazoa relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0006836 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! neurotransmitter transport [Term] id: GO:0005342 name: organic acid transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of organic acids from one side of a membrane to the other. Organic acids are acidic compound containing carbon in covalent linkage." [ISBN:0198506732] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:64709 ! organic acid relationship: has_primary_input CHEBI:64709 ! organic acid relationship: part_of GO:1903825 ! organic acid transmembrane transport [Term] id: GO:0005355 name: glucose transmembrane transporter activity namespace: molecular_function alt_id: GO:0015579 def: "Enables the transfer of the hexose monosaccharide glucose from one side of a membrane to the other." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] synonym: "galactose/glucose (methylgalactoside) porter activity" RELATED [] synonym: "glucose permease activity" EXACT [] synonym: "lactose/glucose efflux transporter activity" NARROW [] xref: Reactome:R-HSA-499981 "Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2" xref: Reactome:R-HSA-5653873 "SLC2A1 tetramer transports Glc from cytosol to Golgi lumen" is_a: GO:0015149 ! hexose transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:17234 ! glucose relationship: has_primary_input CHEBI:17234 ! glucose relationship: part_of GO:1904659 ! glucose transmembrane transport [Term] id: GO:0005575 name: cellular_component namespace: cellular_component alt_id: GO:0008372 def: "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex)." [GOC:pdt] comment: Note that, in addition to forming the root of the cellular component ontology, this term is recommended for the annotation of gene products whose cellular component is unknown. When this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. subset: goslim_candida subset: goslim_chembl subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant subset: goslim_yeast synonym: "cell or subcellular entity" EXACT [] synonym: "cellular component" EXACT [] synonym: "subcellular entity" RELATED [NIF_Subcellular:nlx_subcell_100315] xref: NIF_Subcellular:sao1337158144 is_a: BFO:0000040 ! material entity disjoint_from: GO:0008150 ! biological process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/17729" xsd:anyURI [Term] id: GO:0005576 name: extracellular region namespace: cellular_component def: "The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite." [GOC:go_curators] comment: Note that this term is intended to annotate gene products that are not attached to the cell surface. For gene products from multicellular organisms which are secreted from a cell but retained within the organism (i.e. released into the interstitial fluid or blood), consider the cellular component term 'extracellular space ; GO:0005615'. subset: goslim_agr subset: goslim_candida subset: goslim_chembl subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_metagenomics subset: goslim_mouse subset: goslim_pir subset: goslim_plant subset: goslim_prokaryote subset: goslim_yeast synonym: "extracellular" EXACT [] xref: Wikipedia:Extracellular is_a: GO:0110165 ! cellular anatomical entity [Term] id: GO:0005577 name: fibrinogen complex namespace: cellular_component def: "A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (alpha, beta, and gamma) linked together by disulfide bonds." [ISBN:0198547684] synonym: "fibrinogen" EXACT [] synonym: "fibrinogen alpha chain" NARROW [] synonym: "fibrinogen beta chain" NARROW [] synonym: "fibrinogen gamma chain" NARROW [] is_a: GO:0032991 ! protein-containing complex relationship: part_of GO:0005615 ! extracellular space [Term] id: GO:0005581 name: collagen trimer namespace: cellular_component def: "A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures." [GOC:dos, GOC:mah, ISBN:0721639976, PMID:19693541, PMID:21421911] xref: Wikipedia:Collagen is_a: GO:0032991 ! protein-containing complex relationship: in_taxon NCBITaxon:33208 {all_only="true", source="PMID:12382326"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 {source="PMID:12382326"} ! Metazoa [Term] id: GO:0005583 name: fibrillar collagen trimer namespace: cellular_component def: "Any triple helical collagen trimer that forms fibrils." [GOC:mah, ISBN:0721639976, PMID:21421911] is_a: GO:0005581 ! collagen trimer intersection_of: GO:0005581 ! collagen trimer intersection_of: part_of GO:0098643 ! banded collagen fibril disjoint_from: GO:0030936 ! transmembrane collagen trimer relationship: part_of GO:0098643 ! banded collagen fibril [Term] id: GO:0005587 name: collagen type IV trimer namespace: cellular_component def: "A collagen heterotrimer containing type IV alpha chains; [alpha1(IV)]2alpha2(IV) trimers are commonly observed, although more type IV alpha chains exist and may be present in type IV trimers; type IV collagen triple helices associate to form 3 dimensional nets within basement membranes." [ISBN:0721639976, PMID:19693541, PMID:21421911] xref: Wikipedia:Collagen_type_IV is_a: GO:0098642 ! network-forming collagen trimer is_a: GO:0098651 ! basement membrane collagen trimer [Term] id: GO:0005604 name: basement membrane namespace: cellular_component alt_id: GO:0005605 alt_id: GO:0008003 def: "A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers." [ISBN:0198547684, PMID:22505934] comment: Note that this term has no relationship to 'membrane ; GO:0016020' because the basement membrane is not a lipid bilayer. synonym: "basal lamina" RELATED [] synonym: "basement lamina" RELATED [] synonym: "lamina densa" RELATED [] xref: Wikipedia:Basement_membrane is_a: GO:0062023 ! collagen-containing extracellular matrix [Term] id: GO:0005615 name: extracellular space namespace: cellular_component def: "That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid." [ISBN:0198547684] comment: Note that for multicellular organisms, the extracellular space refers to everything outside a cell, but still within the organism (excluding the extracellular matrix). Gene products from a multi-cellular organism that are secreted from a cell into the interstitial fluid or blood can therefore be annotated to this term. subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_prokaryote synonym: "intercellular space" RELATED [] xref: NIF_Subcellular:sao1425028079 is_a: GO:0110165 ! cellular anatomical entity relationship: part_of GO:0005576 ! extracellular region [Term] id: GO:0005622 name: intracellular anatomical structure namespace: cellular_component def: "A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm." [ISBN:0198506732] subset: gocheck_do_not_annotate subset: goslim_chembl subset: goslim_metagenomics subset: goslim_plant synonym: "internal to cell" EXACT [] synonym: "intracellular" EXACT [] synonym: "nucleocytoplasm" RELATED [GOC:mah] synonym: "protoplasm" EXACT [] synonym: "protoplast" RELATED [GOC:mah] xref: Wikipedia:Intracellular is_a: GO:0110165 ! cellular anatomical entity relationship: part_of CL:0000000 ! cell property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/17776" xsd:anyURI [Term] id: GO:0005634 name: nucleus namespace: cellular_component def: "A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent." [GOC:go_curators] subset: goslim_agr subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_metagenomics subset: goslim_mouse subset: goslim_pir subset: goslim_plant subset: goslim_yeast synonym: "cell nucleus" EXACT [] synonym: "horsetail nucleus" NARROW [GOC:al, GOC:mah, GOC:vw, PMID:15030757] xref: NIF_Subcellular:sao1702920020 xref: Wikipedia:Cell_nucleus is_a: GO:0043231 ! intracellular membrane-bounded organelle disjoint_from: GO:0005737 ! cytoplasm relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota [Term] id: GO:0005635 name: nuclear envelope namespace: cellular_component alt_id: GO:0005636 def: "The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space)." [ISBN:0198547684] subset: goslim_chembl subset: goslim_generic subset: goslim_plant xref: Wikipedia:Nuclear_envelope is_a: GO:0031967 ! organelle envelope relationship: part_of GO:0005634 ! nucleus relationship: part_of GO:0012505 ! endomembrane system [Term] id: GO:0005640 name: nuclear outer membrane namespace: cellular_component def: "The outer, i.e. cytoplasm-facing, lipid bilayer of the nuclear envelope; continuous with the endoplasmic reticulum of the cell and sometimes studded with ribosomes." [ISBN:0198547684] synonym: "nucleus outer envelope" EXACT [] synonym: "perinuclear membrane" EXACT [] xref: NIF_Subcellular:sao1617136075 is_a: GO:0031965 ! nuclear membrane is_a: GO:0031968 ! organelle outer membrane intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0005634 ! nucleus relationship: bounding_layer_of GO:0005634 ! nucleus relationship: part_of GO:0042175 ! nuclear outer membrane-endoplasmic reticulum membrane network [Term] id: GO:0005694 name: chromosome namespace: cellular_component def: "A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information." [ISBN:0198547684] comment: Chromosomes include parts that are not part of the chromatin. Examples include the kinetochore. subset: goslim_agr subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir subset: goslim_prokaryote subset: goslim_yeast synonym: "chromatid" RELATED [] synonym: "interphase chromosome" NARROW [] synonym: "prophase chromosome" NARROW [] xref: Wikipedia:Chromosome is_a: GO:0043232 ! intracellular non-membrane-bounded organelle [Term] id: GO:0005730 name: nucleolus namespace: cellular_component def: "A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome." [ISBN:0198506732] subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_pir subset: goslim_plant subset: goslim_yeast xref: NIF_Subcellular:sao1820400233 xref: Wikipedia:Nucleolus is_a: GO:0043232 ! intracellular non-membrane-bounded organelle relationship: part_of GO:0031981 ! nuclear lumen [Term] id: GO:0005737 name: cytoplasm namespace: cellular_component def: "The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." [ISBN:0198547684] subset: goslim_candida subset: goslim_chembl subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant subset: goslim_prokaryote subset: goslim_yeast xref: Wikipedia:Cytoplasm is_a: GO:0110165 ! cellular anatomical entity relationship: part_of GO:0005622 ! intracellular anatomical structure property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23023" xsd:anyURI [Term] id: GO:0005773 name: vacuole namespace: cellular_component def: "A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol." [GOC:mtg_sensu, ISBN:0198506732] subset: goslim_agr subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_mouse subset: goslim_pir subset: goslim_plant subset: goslim_yeast synonym: "vacuolar carboxypeptidase Y" RELATED [] xref: Wikipedia:Vacuole is_a: GO:0043231 ! intracellular membrane-bounded organelle relationship: part_of GO:0005737 ! cytoplasm [Term] id: GO:0005774 name: vacuolar membrane namespace: cellular_component def: "The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell." [GOC:ai] is_a: GO:0098588 ! bounding membrane of organelle intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0005773 ! vacuole relationship: bounding_layer_of GO:0005773 ! vacuole relationship: part_of GO:0005773 ! vacuole [Term] id: GO:0005775 name: vacuolar lumen namespace: cellular_component def: "The volume enclosed within the vacuolar membrane." [ISBN:0198506732] is_a: GO:0070013 ! intracellular organelle lumen intersection_of: GO:0031974 ! membrane-enclosed lumen intersection_of: part_of GO:0005773 ! vacuole relationship: part_of GO:0005773 ! vacuole [Term] id: GO:0005794 name: Golgi apparatus namespace: cellular_component def: "A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways." [ISBN:0198506732] comment: Note that the Golgi apparatus can be located in various places in the cytoplasm. In plants and lower animal cells, the Golgi apparatus exists as many copies of discrete stacks dispersed throughout the cytoplasm, while the Golgi apparatus of interphase mammalian cells is a juxtanuclear, often pericentriolar reticulum, where the discrete Golgi stacks are stitched together to form a compact and interconnected ribbon, sometimes called the Golgi ribbon. subset: goslim_agr subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_mouse subset: goslim_pir subset: goslim_plant subset: goslim_yeast synonym: "Golgi" BROAD [] synonym: "Golgi complex" EXACT [] synonym: "Golgi ribbon" NARROW [] xref: NIF_Subcellular:sao451912436 xref: Wikipedia:Golgi_apparatus is_a: GO:0043231 ! intracellular membrane-bounded organelle relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota relationship: part_of GO:0005737 ! cytoplasm relationship: part_of GO:0012505 ! endomembrane system [Term] id: GO:0005798 name: Golgi-associated vesicle namespace: cellular_component def: "Any vesicle associated with the Golgi complex and involved in mediating transport within the Golgi or between the Golgi and other parts of the cell." [GOC:mah] comment: Note that this definition includes vesicles that are transiently associated with the Golgi. synonym: "Golgi vesicle" RELATED [] synonym: "vesicular component" RELATED [NIF_Subcellular:sao138219748] xref: NIF_Subcellular:sao819927218 is_a: GO:0031410 ! cytoplasmic vesicle [Term] id: GO:0005840 name: ribosome namespace: cellular_component alt_id: GO:0033279 def: "An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins." [ISBN:0198506732] subset: goslim_candida subset: goslim_chembl subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant subset: goslim_prokaryote subset: goslim_yeast synonym: "free ribosome" NARROW [NIF_Subcellular:sao1139385046] synonym: "membrane bound ribosome" NARROW [NIF_Subcellular:sao1291545653] synonym: "ribosomal RNA" RELATED [] xref: NIF_Subcellular:sao1429207766 xref: Wikipedia:Ribosome is_a: GO:0043232 ! intracellular non-membrane-bounded organelle is_a: PR:000050567 ! protein-containing material entity relationship: capable_of_part_of GO:0006412 ! translation relationship: has_part CHEBI:33697 ! ribonucleic acid [Term] id: GO:0005856 name: cytoskeleton namespace: cellular_component def: "A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles." [GOC:mah, PMID:16959967, PMID:27419875] subset: goslim_agr subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_mouse subset: goslim_pir subset: goslim_plant subset: goslim_prokaryote subset: goslim_yeast xref: Wikipedia:Cytoskeleton is_a: GO:0043232 ! intracellular non-membrane-bounded organelle [Term] id: GO:0005874 name: microtubule namespace: cellular_component def: "Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle." [ISBN:0879693568] subset: goslim_metagenomics synonym: "microtubuli" EXACT [] synonym: "microtubulus" EXACT [] synonym: "neurotubule" NARROW [NIF_Subcellular:sao248349196] xref: NIF_Subcellular:sao1846835077 xref: Wikipedia:Microtubule is_a: GO:0099513 ! polymeric cytoskeletal fiber relationship: part_of GO:0015630 ! microtubule cytoskeleton [Term] id: GO:0005879 name: axonemal microtubule namespace: cellular_component def: "A microtubule in the axoneme of a eukaryotic cilium or flagellum; an axoneme contains nine modified doublet microtubules, which may or may not surround a pair of single microtubules." [GOC:cilia, ISBN:0815316194] is_a: GO:0005881 ! cytoplasmic microtubule intersection_of: GO:0005874 ! microtubule intersection_of: part_of GO:0005930 ! axoneme relationship: part_of GO:0005930 ! axoneme [Term] id: GO:0005880 name: nuclear microtubule namespace: cellular_component def: "Any microtubule in the nucleus of a cell." [GOC:mah] is_a: GO:0005874 ! microtubule intersection_of: GO:0005874 ! microtubule intersection_of: part_of GO:0005634 ! nucleus relationship: part_of GO:0005634 ! nucleus [Term] id: GO:0005881 name: cytoplasmic microtubule namespace: cellular_component def: "Any microtubule in the cytoplasm of a cell." [GOC:mah] synonym: "non-spindle-associated astral microtubule" NARROW [] is_a: GO:0005874 ! microtubule intersection_of: GO:0005874 ! microtubule intersection_of: part_of GO:0005737 ! cytoplasm relationship: part_of GO:0005737 ! cytoplasm [Term] id: GO:0005884 name: actin filament namespace: cellular_component def: "A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane." [GOC:mah, ISBN:0198506732, PMID:10666339] synonym: "microfilament" EXACT [] xref: FMA:63850 xref: NIF_Subcellular:sao1588493326 xref: Wikipedia:Actin is_a: GO:0099513 ! polymeric cytoskeletal fiber relationship: part_of GO:0015629 ! actin cytoskeleton [Term] id: GO:0005886 name: plasma membrane namespace: cellular_component alt_id: GO:0005887 alt_id: GO:0005904 def: "The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins." [ISBN:0716731363] subset: goslim_agr subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_metagenomics subset: goslim_mouse subset: goslim_plant subset: goslim_prokaryote subset: goslim_yeast synonym: "bacterial inner membrane" NARROW [] synonym: "cell membrane" EXACT [] synonym: "cellular membrane" EXACT [NIF_Subcellular:sao6433132645] synonym: "cytoplasmic membrane" EXACT [] synonym: "inner endospore membrane" NARROW [] synonym: "integral component of plasma membrane" NARROW [] synonym: "integral to plasma membrane" NARROW [] synonym: "juxtamembrane" BROAD [] synonym: "plasma membrane lipid bilayer" NARROW [GOC:mah] synonym: "plasmalemma" EXACT [] xref: NIF_Subcellular:sao1663586795 xref: Wikipedia:Cell_membrane is_a: GO:0016020 ! membrane relationship: part_of GO:0071944 ! cell periphery [Term] id: GO:0005902 name: microvillus namespace: cellular_component def: "Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. Present in especially large numbers on the absorptive surface of intestinal cells." [ISBN:0815316194] comment: Note that this term refers to a projection from a single cell, and should not be confused with 'microvillus' as used to refer to a multicellular structure such as that found in the placenta. subset: goslim_pir synonym: "microvilli" RELATED [NIF_Subcellular:sao671419673] xref: NIF_Subcellular:sao671419673 xref: Wikipedia:Microvillus is_a: GO:0098858 ! actin-based cell projection relationship: has_part GO:0032432 ! actin filament bundle relationship: part_of CL:0000066 ! epithelial cell property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0005911 name: cell-cell junction namespace: cellular_component def: "A cell junction that forms a connection between two or more cells of an organism; excludes direct cytoplasmic intercellular bridges, such as ring canals in insects." [GOC:aruk, GOC:bc, GOC:dgh, GOC:hb, GOC:mah, PMID:21422226, PMID:28096264] synonym: "cell-cell contact region" BROAD [] synonym: "cell-cell contact zone" BROAD [] synonym: "intercellular junction" EXACT [NIF_Subcellular:sao1395777368] xref: NIF_Subcellular:sao1922892319 is_a: GO:0070161 ! anchoring junction property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22122" xsd:anyURI [Term] id: GO:0005929 name: cilium namespace: cellular_component alt_id: GO:0072372 def: "A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body." [GOC:cilia, GOC:curators, GOC:kmv, GOC:vw, ISBN:0198547684, PMID:16824949, PMID:17009929, PMID:20144998] comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. In most eukaryotic species, intracellular sub-components of the cilium, such as the ciliary base and rootlet, are located near the plasma membrane. In Diplomonads such as Giardia, instead, the same ciliary parts are located further intracellularly. Also, 'cilium' may be used when axonemal structure and/or motility are unknown, or when axonemal structure is unusual. For all other cases, please refer to children of 'cilium'. Finally, note that any role of ciliary proteins in sensory events should be captured by annotating to relevant biological process terms. subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_pir synonym: "eukaryotic flagellum" EXACT [] synonym: "flagellum" RELATED [] synonym: "microtubule-based flagellum" EXACT [] synonym: "primary cilium" NARROW [] xref: FMA:67181 xref: NIF_Subcellular:sao787716553 xref: Wikipedia:Cilium is_a: GO:0043227 ! membrane-bounded organelle is_a: GO:0120025 ! plasma membrane bounded cell projection is_a: PR:000050567 ! protein-containing material entity relationship: has_part GO:0030990 ! intraciliary transport particle relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3312 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4890 property_value: RO:0002161 NCBITaxon:5782 [Term] id: GO:0005930 name: axoneme namespace: cellular_component alt_id: GO:0035085 alt_id: GO:0035086 def: "The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements." [GOC:bf, GOC:cilia, ISBN:0198547684] comment: Note that cilia and eukaryotic flagella are deemed to be equivalent. In diplomonad species, such as Giardia, the axoneme may extend intracellularly up to 5um away from the plane of the plasma membrane. subset: goslim_pir synonym: "ciliary axoneme" EXACT [] synonym: "cilium axoneme" EXACT [] synonym: "flagellar axoneme" EXACT [] synonym: "flagellum axoneme" EXACT [] xref: Wikipedia:Axoneme is_a: GO:0110165 ! cellular anatomical entity relationship: has_part GO:0005874 ! microtubule relationship: part_of GO:0005856 ! cytoskeleton relationship: part_of GO:0097014 ! ciliary plasm [Term] id: GO:0005938 name: cell cortex namespace: cellular_component def: "The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins." [GOC:mah, ISBN:0815316194] subset: goslim_candida subset: goslim_yeast synonym: "cell periphery" RELATED [] synonym: "ectoplasm" NARROW [] synonym: "peripheral cytoplasm" RELATED [] xref: Wikipedia:Cell_cortex is_a: GO:0005737 ! cytoplasm intersection_of: GO:0005737 ! cytoplasm intersection_of: part_of GO:0071944 ! cell periphery relationship: part_of GO:0071944 ! cell periphery property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26298" xsd:anyURI [Term] id: GO:0005975 name: carbohydrate metabolic process namespace: biological_process alt_id: GO:0044261 alt_id: GO:0044723 def: "The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y." [GOC:mah, ISBN:0198506732] subset: goslim_agr subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant subset: goslim_pombe subset: goslim_prokaryote subset: goslim_yeast synonym: "carbohydrate metabolism" EXACT [] xref: Wikipedia:Carbohydrate_metabolism is_a: GO:0044238 ! primary metabolic process is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:16646 ! carbohydrate relationship: has_primary_input_or_output CHEBI:16646 ! carbohydrate property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22880" xsd:anyURI created_by: jl creation_date: 2012-10-23T15:40:34Z [Term] id: GO:0005976 name: polysaccharide metabolic process namespace: biological_process alt_id: GO:0044263 def: "The chemical reactions and pathways involving a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." [ISBN:0198547684] subset: goslim_pir synonym: "glycan metabolic process" NARROW [] synonym: "glycan metabolism" NARROW [] synonym: "multicellular organismal polysaccharide metabolic process" NARROW [] synonym: "polysaccharide metabolism" EXACT [] is_a: GO:0005975 ! carbohydrate metabolic process is_a: GO:0043170 ! macromolecule metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:18154 ! polysaccharide relationship: has_primary_input_or_output CHEBI:18154 ! polysaccharide [Term] id: GO:0005977 name: glycogen metabolic process namespace: biological_process def: "The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages." [ISBN:0198506732] synonym: "glycogen metabolism" EXACT [] is_a: GO:0006112 ! energy reserve metabolic process is_a: GO:0044042 ! glucan metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:28087 ! glycogen relationship: has_primary_input_or_output CHEBI:28087 ! glycogen [Term] id: GO:0005978 name: glycogen biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues." [ISBN:0198506732] synonym: "glycogen anabolism" EXACT [] synonym: "glycogen biosynthesis" EXACT [] synonym: "glycogen formation" EXACT [] synonym: "glycogen synthesis" EXACT [] xref: MetaCyc:GLYCOGENSYNTH-PWY is_a: GO:0005977 ! glycogen metabolic process is_a: GO:0009250 ! glucan biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:28087 ! glycogen relationship: has_primary_output CHEBI:28087 ! glycogen [Term] id: GO:0005979 name: regulation of glycogen biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen." [GOC:go_curators] synonym: "regulation of glycogen anabolism" EXACT [] synonym: "regulation of glycogen biosynthesis" EXACT [] synonym: "regulation of glycogen formation" EXACT [] synonym: "regulation of glycogen synthesis" EXACT [] is_a: GO:0010962 ! regulation of glucan biosynthetic process is_a: GO:0070873 ! regulation of glycogen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0005978 ! glycogen biosynthetic process relationship: regulates GO:0005978 ! glycogen biosynthetic process [Term] id: GO:0005980 name: glycogen catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues." [ISBN:0198506732] synonym: "glycogen breakdown" EXACT [] synonym: "glycogen catabolism" EXACT [] synonym: "glycogen degradation" EXACT [] synonym: "glycogenolysis" EXACT [GOC:sl] xref: MetaCyc:GLYCOCAT-PWY is_a: GO:0005977 ! glycogen metabolic process is_a: GO:0009251 ! glucan catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:28087 ! glycogen relationship: has_primary_input CHEBI:28087 ! glycogen [Term] id: GO:0005981 name: regulation of glycogen catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen." [GOC:go_curators] synonym: "regulation of glycogen breakdown" EXACT [] synonym: "regulation of glycogen catabolism" EXACT [] synonym: "regulation of glycogen degradation" EXACT [] synonym: "regulation of glycogenolysis" EXACT [GOC:sl] is_a: GO:0043470 ! regulation of carbohydrate catabolic process is_a: GO:0070873 ! regulation of glycogen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0005980 ! glycogen catabolic process relationship: regulates GO:0005980 ! glycogen catabolic process [Term] id: GO:0005996 name: monosaccharide metabolic process namespace: biological_process def: "The chemical reactions and pathways involving monosaccharides, the simplest carbohydrates. They are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides." [ISBN:0198506732] synonym: "monosaccharide metabolism" EXACT [] is_a: GO:0005975 ! carbohydrate metabolic process is_a: GO:0044281 ! small molecule metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:35381 ! monosaccharide relationship: has_primary_input_or_output CHEBI:35381 ! monosaccharide [Term] id: GO:0006006 name: glucose metabolic process namespace: biological_process def: "The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides." [ISBN:0198506732] synonym: "cellular glucose metabolic process" EXACT [GOC:vw] synonym: "glucose metabolism" EXACT [] is_a: GO:0019318 ! hexose metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:17234 ! glucose relationship: has_primary_input_or_output CHEBI:17234 ! glucose [Term] id: GO:0006007 name: glucose catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of glucose, the aldohexose gluco-hexose." [GOC:ai] synonym: "glucose breakdown" EXACT [] synonym: "glucose catabolism" EXACT [] synonym: "glucose degradation" EXACT [] is_a: GO:0006006 ! glucose metabolic process is_a: GO:0019320 ! hexose catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:17234 ! glucose relationship: has_primary_input CHEBI:17234 ! glucose [Term] id: GO:0006022 name: aminoglycan metabolic process namespace: biological_process def: "The chemical reactions and pathways involving aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages." [GOC:ai, ISBN:0198506732] synonym: "aminoglycan metabolism" EXACT [] is_a: GO:0043170 ! macromolecule metabolic process is_a: GO:1901135 ! carbohydrate derivative metabolic process is_a: GO:1901564 ! organonitrogen compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:22506 ! aminoglycan relationship: has_primary_input_or_output CHEBI:22506 ! aminoglycan [Term] id: GO:0006023 name: aminoglycan biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages." [GOC:ai, ISBN:0198506732] synonym: "aminoglycan anabolism" EXACT [] synonym: "aminoglycan biosynthesis" EXACT [] synonym: "aminoglycan formation" EXACT [] synonym: "aminoglycan synthesis" EXACT [] is_a: GO:0006022 ! aminoglycan metabolic process is_a: GO:0009059 ! macromolecule biosynthetic process is_a: GO:1901137 ! carbohydrate derivative biosynthetic process is_a: GO:1901566 ! organonitrogen compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:22506 ! aminoglycan relationship: has_primary_output CHEBI:22506 ! aminoglycan [Term] id: GO:0006024 name: glycosaminoglycan biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of glycosaminoglycans, any of a group of polysaccharides that contain amino sugars." [ISBN:0192800981] synonym: "glycosaminoglycan anabolism" EXACT [] synonym: "glycosaminoglycan biosynthesis" EXACT [] synonym: "glycosaminoglycan formation" EXACT [] synonym: "glycosaminoglycan synthesis" EXACT [] is_a: GO:0006023 ! aminoglycan biosynthetic process is_a: GO:0030203 ! glycosaminoglycan metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:18085 ! glycosaminoglycan relationship: has_primary_output CHEBI:18085 ! glycosaminoglycan [Term] id: GO:0006026 name: aminoglycan catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages." [GOC:ai, ISBN:0198506732] synonym: "aminoglycan breakdown" EXACT [] synonym: "aminoglycan catabolism" EXACT [] synonym: "aminoglycan degradation" EXACT [] is_a: GO:0006022 ! aminoglycan metabolic process is_a: GO:0009057 ! macromolecule catabolic process is_a: GO:1901136 ! carbohydrate derivative catabolic process is_a: GO:1901565 ! organonitrogen compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:22506 ! aminoglycan relationship: has_primary_input CHEBI:22506 ! aminoglycan [Term] id: GO:0006027 name: glycosaminoglycan catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of glycosaminoglycans, any one of a group of polysaccharides that contain amino sugars." [ISBN:0192800981] synonym: "glycosaminoglycan breakdown" EXACT [] synonym: "glycosaminoglycan catabolism" EXACT [] synonym: "glycosaminoglycan degradation" EXACT [] is_a: GO:0006026 ! aminoglycan catabolic process is_a: GO:0030203 ! glycosaminoglycan metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:18085 ! glycosaminoglycan relationship: has_primary_input CHEBI:18085 ! glycosaminoglycan [Term] id: GO:0006030 name: chitin metabolic process namespace: biological_process def: "The chemical reactions and pathways involving chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues." [GOC:jl, ISBN:0198506732] synonym: "beta-1,4-linked N-acetylglucosamine metabolic process" EXACT [] synonym: "beta-1,4-linked N-acetylglucosamine metabolism" EXACT [] synonym: "chitin metabolism" EXACT [] is_a: GO:0006022 ! aminoglycan metabolic process is_a: GO:1901071 ! glucosamine-containing compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:17029 ! chitin relationship: has_primary_input_or_output CHEBI:17029 ! chitin [Term] id: GO:0006031 name: chitin biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues." [GOC:jl, ISBN:0198506732] synonym: "beta-1,4-linked N-acetylglucosamine biosynthesis" EXACT [] synonym: "beta-1,4-linked N-acetylglucosamine biosynthetic process" EXACT [] synonym: "chitin anabolism" EXACT [] synonym: "chitin biosynthesis" EXACT [] synonym: "chitin formation" EXACT [] synonym: "chitin synthesis" EXACT [] is_a: GO:0006023 ! aminoglycan biosynthetic process is_a: GO:0006030 ! chitin metabolic process is_a: GO:1901073 ! glucosamine-containing compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:17029 ! chitin relationship: has_primary_output CHEBI:17029 ! chitin [Term] id: GO:0006032 name: chitin catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues." [GOC:jl, ISBN:0198506732] synonym: "beta-1,4-linked N-acetylglucosamine catabolic process" EXACT [] synonym: "beta-1,4-linked N-acetylglucosamine catabolism" EXACT [] synonym: "chitin breakdown" EXACT [] synonym: "chitin catabolism" EXACT [] synonym: "chitin degradation" EXACT [] is_a: GO:0006026 ! aminoglycan catabolic process is_a: GO:0006030 ! chitin metabolic process is_a: GO:1901072 ! glucosamine-containing compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:17029 ! chitin relationship: has_primary_input CHEBI:17029 ! chitin [Term] id: GO:0006040 name: amino sugar metabolic process namespace: biological_process def: "The chemical reactions and pathways involving any amino sugar, sugars containing an amino group in place of a hydroxyl group." [GOC:jl, ISBN:0192801023] synonym: "amino sugar metabolism" EXACT [] synonym: "aminosaccharide metabolic process" EXACT [] synonym: "aminosaccharide metabolism" EXACT [] is_a: GO:1901135 ! carbohydrate derivative metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:28963 ! amino sugar relationship: has_primary_input_or_output CHEBI:28963 ! amino sugar [Term] id: GO:0006082 name: organic acid metabolic process namespace: biological_process def: "The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage." [ISBN:0198506732] subset: goslim_pir synonym: "organic acid metabolism" EXACT [] is_a: GO:0044237 ! cellular metabolic process is_a: GO:0044281 ! small molecule metabolic process is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:64709 ! organic acid relationship: has_primary_input_or_output CHEBI:64709 ! organic acid [Term] id: GO:0006083 name: acetate metabolic process namespace: biological_process def: "The chemical reactions and pathways involving acetate, the anion of acetic acid." [GOC:go_curators] synonym: "acetate metabolism" EXACT [] is_a: GO:0032787 ! monocarboxylic acid metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:30089 ! acetate relationship: has_primary_input_or_output CHEBI:30089 ! acetate [Term] id: GO:0006091 name: generation of precursor metabolites and energy namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances." [GOC:jl] subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant subset: goslim_pombe subset: goslim_prokaryote subset: goslim_yeast synonym: "energy pathways" BROAD [] synonym: "intermediary metabolism" RELATED [GOC:mah] synonym: "metabolic energy generation" RELATED [] is_a: GO:0044237 ! cellular metabolic process [Term] id: GO:0006094 name: gluconeogenesis namespace: biological_process def: "The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol." [MetaCyc:GLUCONEO-PWY] synonym: "glucose biosynthesis" EXACT [] synonym: "glucose biosynthetic process" EXACT [] xref: MetaCyc:GLUCONEO-PWY xref: Wikipedia:Gluconeogenesis is_a: GO:0006006 ! glucose metabolic process is_a: GO:0019319 ! hexose biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:17234 ! glucose relationship: has_primary_output CHEBI:17234 ! glucose [Term] id: GO:0006109 name: regulation of carbohydrate metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates." [GOC:go_curators] synonym: "regulation of carbohydrate metabolism" EXACT [] is_a: GO:0080090 ! regulation of primary metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0005975 ! carbohydrate metabolic process relationship: regulates GO:0005975 ! carbohydrate metabolic process [Term] id: GO:0006111 name: regulation of gluconeogenesis namespace: biological_process alt_id: GO:0090526 def: "Any process that modulates the frequency, rate or extent of gluconeogenesis, the formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol." [GOC:go_curators] synonym: "regulation of gluconeogenesis involved in cellular glucose homeostasis" RELATED [] synonym: "regulation of glucose biosynthesis" BROAD [] synonym: "regulation of glucose biosynthetic process" BROAD [] is_a: GO:0010906 ! regulation of glucose metabolic process is_a: GO:0043255 ! regulation of carbohydrate biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006094 ! gluconeogenesis relationship: regulates GO:0006094 ! gluconeogenesis created_by: tb creation_date: 2013-01-18T12:47:43Z [Term] id: GO:0006112 name: energy reserve metabolic process namespace: biological_process def: "The chemical reactions and pathways by which a cell derives energy from stored compounds such as fats or glycogen." [GOC:mah] subset: goslim_pir synonym: "energy reserve metabolism" EXACT [] is_a: GO:0015980 ! energy derivation by oxidation of organic compounds [Term] id: GO:0006139 name: nucleobase-containing compound metabolic process namespace: biological_process alt_id: GO:0055134 def: "Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:ai] subset: goslim_pir subset: goslim_plant synonym: "cellular nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT [] synonym: "cellular nucleobase, nucleoside, nucleotide and nucleic acid metabolism" EXACT [] synonym: "nucleobase, nucleoside and nucleotide metabolic process" RELATED [] synonym: "nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" RELATED [GOC:dph, GOC:tb] synonym: "nucleobase, nucleoside, nucleotide and nucleic acid metabolism" EXACT [] is_a: GO:0006725 ! cellular aromatic compound metabolic process is_a: GO:0034641 ! cellular nitrogen compound metabolic process is_a: GO:0044238 ! primary metabolic process is_a: GO:0046483 ! heterocycle metabolic process is_a: GO:1901360 ! organic cyclic compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:61120 ! nucleobase-containing molecular entity relationship: has_primary_input_or_output CHEBI:61120 ! nucleobase-containing molecular entity [Term] id: GO:0006259 name: DNA metabolic process namespace: biological_process alt_id: GO:0055132 def: "Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides." [ISBN:0198506732] subset: goslim_agr subset: goslim_candida subset: goslim_chembl subset: goslim_flybase_ribbon subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant synonym: "cellular DNA metabolism" EXACT [] synonym: "DNA metabolism" EXACT [] is_a: GO:0090304 ! nucleic acid metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:16991 ! deoxyribonucleic acid relationship: has_primary_input_or_output CHEBI:16991 ! deoxyribonucleic acid [Term] id: GO:0006308 name: DNA catabolic process namespace: biological_process def: "The cellular DNA metabolic process resulting in the breakdown of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one." [GOC:go_curators, ISBN:0198506732] synonym: "DNA breakdown" EXACT [] synonym: "DNA catabolism" EXACT [] synonym: "DNA degradation" EXACT [] is_a: GO:0006259 ! DNA metabolic process is_a: GO:0009057 ! macromolecule catabolic process is_a: GO:0034655 ! nucleobase-containing compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:16991 ! deoxyribonucleic acid relationship: has_part GO:0004536 ! DNA nuclease activity relationship: has_primary_input CHEBI:16991 ! deoxyribonucleic acid [Term] id: GO:0006309 name: apoptotic DNA fragmentation namespace: biological_process alt_id: GO:0008178 def: "The cleavage of DNA during apoptosis, which usually occurs in two stages: cleavage into fragments of about 50 kbp followed by cleavage between nucleosomes to yield 200 bp fragments." [GOC:dph, GOC:mah, GOC:mtg_apoptosis, GOC:tb, ISBN:0721639976, PMID:15723341, PMID:23379520] comment: DNA fragmentation in response to apoptotic signals is achieved through the activity of apoptotic nucleases. In human, these include DNA fragmentation factor (DFF) or caspase-activated DNase (CAD) and endonuclease G (Endo G) (reviewed in PMID:15723341). Caution is needed when apoptotic DNA laddering assays show presence of fragmented DNA. A positive assay may simply reflect the end point of a whole apoptotic process. Unless clear experimental evidence is available to show that a gene product is directly involved in fragmenting DNA, please do not annotate to GO:0006309 'apoptotic DNA fragmentation' and consider annotating instead to a more upstream process such as, e.g., GO:0042981 'regulation of apoptotic process', GO:0006915 'apoptotic process', GO:0097190 'apoptotic signaling pathway'. Also, note that gene products involved in compartmentalization of apoptotic nucleases and in activation or repression of their enzymatic activity should be annotated to the regulation term GO:1902510 'regulation of apoptotic DNA fragmentation' or to one of its children (see PMID:15723341). synonym: "chromatinolysis" BROAD [GOC:mtg_apoptosis] synonym: "DNA catabolic process during apoptosis" EXACT [] synonym: "DNA catabolism during apoptosis" EXACT [] synonym: "DNA fragmentation" BROAD [] synonym: "DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:cjm, GOC:dph, GOC:tb] synonym: "endonucleolytic DNA catabolic process involved in apoptosis" EXACT [] is_a: GO:0006308 ! DNA catabolic process intersection_of: GO:0006308 ! DNA catabolic process intersection_of: part_of GO:0030262 ! apoptotic nuclear changes relationship: part_of GO:0030262 ! apoptotic nuclear changes property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24396" xsd:anyURI [Term] id: GO:0006325 name: chromatin organization namespace: biological_process alt_id: GO:0006333 alt_id: GO:0006336 alt_id: GO:0016568 alt_id: GO:0031497 alt_id: GO:0034724 def: "The assembly or remodeling of chromatin composed of DNA complexed with histones, other associated proteins, and sometimes RNA." [PMID:20404130] subset: goslim_generic subset: goslim_pombe subset: goslim_yeast synonym: "chromatin assembly" NARROW [] synonym: "chromatin assembly or disassembly" RELATED [] synonym: "chromatin assembly/disassembly" RELATED [] synonym: "chromatin maintenance" BROAD [] synonym: "chromatin modification" RELATED [] synonym: "chromatin organisation" EXACT [GOC:mah] synonym: "DNA replication-independent chromatin assembly" NARROW [] synonym: "DNA replication-independent chromatin organization" NARROW [] synonym: "DNA replication-independent nucleosome organisation" NARROW [] synonym: "DNA replication-independent nuclesome assembly" NARROW [] synonym: "establishment of chromatin architecture" EXACT [GOC:mah] synonym: "establishment or maintenance of chromatin architecture" EXACT [GOC:mah] synonym: "transcription-coupled nucleosome assembly" NARROW [] is_a: GO:0071824 ! protein-DNA complex organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0000785 ! chromatin relationship: results_in_organization_of GO:0000785 ! chromatin property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22130" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23549" xsd:anyURI [Term] id: GO:0006401 name: RNA catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage." [ISBN:0198506732] subset: goslim_yeast synonym: "RNA breakdown" EXACT [] synonym: "RNA catabolism" EXACT [] synonym: "RNA degradation" EXACT [] is_a: GO:0009057 ! macromolecule catabolic process is_a: GO:0016070 ! RNA metabolic process is_a: GO:0034655 ! nucleobase-containing compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:33697 ! ribonucleic acid relationship: has_primary_input CHEBI:33697 ! ribonucleic acid [Term] id: GO:0006403 name: RNA localization namespace: biological_process def: "A process in which RNA is transported to, or maintained in, a specific location." [GOC:ai] subset: goslim_drosophila synonym: "establishment and maintenance of RNA localization" EXACT [] synonym: "RNA localisation" EXACT [GOC:mah] is_a: GO:0033036 ! macromolecule localization [Term] id: GO:0006412 name: translation namespace: biological_process alt_id: GO:0006416 alt_id: GO:0006453 alt_id: GO:0043037 def: "The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome." [GOC:go_curators] subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant subset: goslim_prokaryote synonym: "protein anabolism" EXACT [] synonym: "protein biosynthesis" EXACT [] synonym: "protein biosynthetic process" EXACT [] synonym: "protein formation" EXACT [] synonym: "protein synthesis" EXACT [] synonym: "protein translation" EXACT [] xref: Wikipedia:Translation_(genetics) is_a: GO:0009059 ! macromolecule biosynthetic process is_a: GO:0019538 ! protein metabolic process is_a: GO:0043043 ! peptide biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:16541 ! protein polypeptide chain intersection_of: part_of GO:0010467 ! gene expression relationship: ends_with GO:0006415 ! translational termination relationship: has_part GO:0006414 ! translational elongation relationship: has_primary_output CHEBI:16541 ! protein polypeptide chain relationship: part_of GO:0010467 ! gene expression relationship: starts_with GO:0006413 ! translational initiation [Term] id: GO:0006413 name: translational initiation namespace: biological_process alt_id: GO:0006440 alt_id: GO:0006454 def: "The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA." [ISBN:019879276X] subset: goslim_yeast synonym: "biopolymerisation" BROAD [] synonym: "biopolymerization" BROAD [] synonym: "protein synthesis initiation" BROAD [] synonym: "translation initiation" EXACT [] is_a: GO:0044237 ! cellular metabolic process relationship: part_of GO:0006412 ! translation relationship: starts_with GO:0001677 ! formation of translation initiation ternary complex [Term] id: GO:0006414 name: translational elongation namespace: biological_process alt_id: GO:0006442 alt_id: GO:0006455 def: "The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis." [GOC:ems] subset: goslim_yeast synonym: "protein synthesis elongation" BROAD [] synonym: "translation elongation" EXACT [] is_a: GO:0009059 ! macromolecule biosynthetic process relationship: part_of GO:0006412 ! translation [Term] id: GO:0006415 name: translational termination namespace: biological_process alt_id: GO:0006443 alt_id: GO:0006456 def: "The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code)." [GOC:hjd, ISBN:019879276X] synonym: "protein synthesis termination" BROAD [] synonym: "translation termination" EXACT [] synonym: "translational complex disassembly" EXACT [] is_a: GO:0032984 ! protein-containing complex disassembly relationship: part_of GO:0006412 ! translation [Term] id: GO:0006417 name: regulation of translation namespace: biological_process alt_id: GO:0006445 def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA." [GOC:isa_complete] subset: goslim_yeast synonym: "regulation of protein anabolism" EXACT [] synonym: "regulation of protein biosynthesis" EXACT [] synonym: "regulation of protein formation" EXACT [] synonym: "regulation of protein synthesis" EXACT [] is_a: GO:0010608 ! post-transcriptional regulation of gene expression is_a: GO:0034248 ! regulation of amide metabolic process is_a: GO:0051246 ! regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006412 ! translation relationship: regulates GO:0006412 ! translation [Term] id: GO:0006446 name: regulation of translational initiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of translational initiation." [GOC:go_curators] is_a: GO:0006417 ! regulation of translation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006413 ! translational initiation relationship: regulates GO:0006413 ! translational initiation [Term] id: GO:0006448 name: regulation of translational elongation namespace: biological_process def: "Any process that modulates the frequency, rate, extent or accuracy of translational elongation." [GOC:go_curators] is_a: GO:0006417 ! regulation of translation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006414 ! translational elongation relationship: regulates GO:0006414 ! translational elongation [Term] id: GO:0006449 name: regulation of translational termination namespace: biological_process def: "Any process that modulates the frequency, rate or extent of translational termination." [GOC:go_curators] is_a: GO:0006417 ! regulation of translation is_a: GO:0043244 ! regulation of protein-containing complex disassembly intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006415 ! translational termination relationship: regulates GO:0006415 ! translational termination [Term] id: GO:0006516 name: glycoprotein catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:go_curators, ISBN:0198506732] synonym: "glycoprotein breakdown" EXACT [] synonym: "glycoprotein catabolism" EXACT [] synonym: "glycoprotein degradation" EXACT [] is_a: GO:0009057 ! macromolecule catabolic process is_a: GO:0009100 ! glycoprotein metabolic process is_a: GO:1901136 ! carbohydrate derivative catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:17089 ! glycoprotein relationship: has_primary_input CHEBI:17089 ! glycoprotein [Term] id: GO:0006518 name: peptide metabolic process namespace: biological_process def: "The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another." [GOC:go_curators] subset: goslim_pir synonym: "peptide metabolism" EXACT [] is_a: GO:0043603 ! amide metabolic process is_a: GO:1901564 ! organonitrogen compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:16670 ! peptide relationship: has_primary_input_or_output CHEBI:16670 ! peptide [Term] id: GO:0006520 name: amino acid metabolic process namespace: biological_process alt_id: GO:0006519 def: "The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups." [ISBN:0198506732] subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_pir subset: goslim_pombe subset: goslim_prokaryote subset: goslim_yeast synonym: "amino acid and derivative metabolism" RELATED [] synonym: "cellular amino acid and derivative metabolic process" RELATED [] synonym: "cellular amino acid metabolic process" EXACT [] synonym: "cellular amino acid metabolism" EXACT [] is_a: GO:0044238 ! primary metabolic process is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:35238 ! amino acid zwitterion relationship: has_primary_input_or_output CHEBI:35238 ! amino acid zwitterion property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/17904" xsd:anyURI [Term] id: GO:0006521 name: regulation of cellular amino acid metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids." [GOC:go_curators] synonym: "regulation of amino acid metabolism" EXACT [] is_a: GO:0010565 ! regulation of cellular ketone metabolic process is_a: GO:0033238 ! regulation of amine metabolic process is_a: GO:0080090 ! regulation of primary metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006520 ! amino acid metabolic process relationship: regulates GO:0006520 ! amino acid metabolic process [Term] id: GO:0006576 name: biogenic amine metabolic process namespace: biological_process def: "The chemical reactions and pathways occurring at the level of individual cells involving any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters." [GOC:jl, ISBN:0395825172] synonym: "biogenic amine metabolism" EXACT [] synonym: "cellular biogenic amine metabolic process" EXACT [] is_a: GO:0009308 ! amine metabolic process [Term] id: GO:0006581 name: acetylcholine catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of acetylcholine, the acetic acid ester of the organic base choline." [GOC:jl, ISBN:0192800752] synonym: "acetylcholine breakdown" EXACT [] synonym: "acetylcholine catabolism" EXACT [] synonym: "acetylcholine degradation" EXACT [] is_a: GO:0008291 ! acetylcholine metabolic process is_a: GO:1901575 ! organic substance catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:15355 ! acetylcholine relationship: has_primary_input CHEBI:15355 ! acetylcholine [Term] id: GO:0006584 name: catecholamine metabolic process namespace: biological_process def: "The chemical reactions and pathways involving any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." [GOC:jl, ISBN:0198506732] synonym: "catecholamine metabolism" EXACT [] is_a: GO:0006576 ! biogenic amine metabolic process is_a: GO:0009712 ! catechol-containing compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:33567 ! catecholamine relationship: has_primary_input_or_output CHEBI:33567 ! catecholamine [Term] id: GO:0006586 name: indolalkylamine metabolic process namespace: biological_process def: "The chemical reactions and pathways involving indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group." [GOC:curators] synonym: "indolalkylamine metabolism" EXACT [] synonym: "indolamine metabolic process" BROAD [] synonym: "indolamine metabolism" BROAD [] is_a: GO:0006576 ! biogenic amine metabolic process is_a: GO:0042430 ! indole-containing compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:38631 ! aminoalkylindole relationship: has_primary_input_or_output CHEBI:38631 ! aminoalkylindole [Term] id: GO:0006629 name: lipid metabolic process namespace: biological_process def: "The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids." [GOC:ma] subset: goslim_agr subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_metagenomics subset: goslim_mouse subset: goslim_pir subset: goslim_plant subset: goslim_pombe subset: goslim_prokaryote subset: goslim_yeast synonym: "lipid metabolism" EXACT [] xref: Wikipedia:Lipid_metabolism is_a: GO:0044238 ! primary metabolic process is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:18059 ! lipid relationship: has_primary_input_or_output CHEBI:18059 ! lipid [Term] id: GO:0006694 name: steroid biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification." [GOC:go_curators] synonym: "steroid anabolism" EXACT [] synonym: "steroid biosynthesis" EXACT [] synonym: "steroid formation" EXACT [] synonym: "steroid synthesis" EXACT [] synonym: "steroidogenesis" EXACT [] xref: Wikipedia:Steroid_metabolisms#Steroid_biosynthesis is_a: GO:0008202 ! steroid metabolic process is_a: GO:0008610 ! lipid biosynthetic process is_a: GO:1901362 ! organic cyclic compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:35341 ! steroid relationship: has_primary_output CHEBI:35341 ! steroid [Term] id: GO:0006699 name: bile acid biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of bile acids, any of a group of steroid carboxylic acids occurring in bile." [GOC:go_curators] synonym: "bile acid anabolism" EXACT [] synonym: "bile acid biosynthesis" EXACT [] synonym: "bile acid formation" EXACT [] synonym: "bile acid synthesis" EXACT [] is_a: GO:0006694 ! steroid biosynthetic process is_a: GO:0008206 ! bile acid metabolic process is_a: GO:0072330 ! monocarboxylic acid biosynthetic process is_a: GO:1901617 ! organic hydroxy compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:36235 ! bile acid anion relationship: has_primary_output CHEBI:36235 ! bile acid anion [Term] id: GO:0006706 name: steroid catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus." [GOC:go_curators] synonym: "steroid breakdown" EXACT [] synonym: "steroid catabolism" EXACT [] synonym: "steroid degradation" EXACT [] is_a: GO:0008202 ! steroid metabolic process is_a: GO:0016042 ! lipid catabolic process is_a: GO:1901361 ! organic cyclic compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:35341 ! steroid relationship: has_primary_input CHEBI:35341 ! steroid [Term] id: GO:0006725 name: cellular aromatic compound metabolic process namespace: biological_process def: "The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells." [GOC:ai, ISBN:0198506732] subset: goslim_pir synonym: "aromatic compound metabolism" EXACT [] synonym: "aromatic hydrocarbon metabolic process" NARROW [] synonym: "aromatic hydrocarbon metabolism" NARROW [] is_a: GO:0044237 ! cellular metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:33655 ! aromatic compound relationship: has_primary_input_or_output CHEBI:33655 ! aromatic compound [Term] id: GO:0006790 name: sulfur compound metabolic process namespace: biological_process def: "The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione." [GOC:ai] subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_pir subset: goslim_pombe subset: goslim_prokaryote synonym: "sulfur metabolism" EXACT [] synonym: "sulphur metabolic process" EXACT [] synonym: "sulphur metabolism" EXACT [] xref: Wikipedia:Sulfur_metabolism is_a: GO:0044237 ! cellular metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:26835 ! sulfur molecular entity relationship: has_primary_input_or_output CHEBI:26835 ! sulfur molecular entity [Term] id: GO:0006793 name: phosphorus metabolic process namespace: biological_process def: "The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4)." [GOC:ai] subset: goslim_pir synonym: "phosphorus metabolism" EXACT [] is_a: GO:0044237 ! cellular metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:26082 ! phosphorus molecular entity relationship: has_primary_input_or_output CHEBI:26082 ! phosphorus molecular entity [Term] id: GO:0006796 name: phosphate-containing compound metabolic process namespace: biological_process def: "The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid." [GOC:ai] synonym: "phosphate metabolic process" RELATED [] synonym: "phosphate metabolism" EXACT [] is_a: GO:0006793 ! phosphorus metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:26020 ! phosphate relationship: has_primary_input_or_output CHEBI:26020 ! phosphate [Term] id: GO:0006807 name: nitrogen compound metabolic process namespace: biological_process def: "The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen." [GOC:jl, ISBN:0198506732] subset: gocheck_do_not_annotate subset: goslim_metagenomics subset: goslim_pir synonym: "nitrogen compound metabolism" EXACT [] is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:51143 ! nitrogen molecular entity relationship: has_primary_input_or_output CHEBI:51143 ! nitrogen molecular entity property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI [Term] id: GO:0006810 name: transport namespace: biological_process alt_id: GO:0015457 alt_id: GO:0015460 alt_id: GO:0044765 def: "The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or a transporter complex, a pore or a motor protein." [GOC:dos, GOC:dph, GOC:jl, GOC:mah] comment: Note that this term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term, for e.g. to transmembrane transport, to microtubule-based transport or to vesicle-mediated transport. subset: gocheck_do_not_annotate subset: goslim_candida subset: goslim_chembl subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant subset: goslim_prokaryote synonym: "single-organism transport" RELATED [] is_a: GO:0051234 ! establishment of localization property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/20292" xsd:anyURI created_by: jl creation_date: 2012-12-13T16:25:32Z [Term] id: GO:0006811 name: monoatomic ion transport namespace: biological_process def: "The directed movement of a monoatomic ion into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monatomic ions (also called simple ions) are ions consisting of exactly one atom." [GOC:ai] subset: goslim_drosophila subset: goslim_pir subset: goslim_yeast synonym: "ion transport" BROAD [] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:24867 ! monoatomic ion relationship: has_primary_input CHEBI:24867 ! monoatomic ion [Term] id: GO:0006812 name: monoatomic cation transport namespace: biological_process alt_id: GO:0006819 alt_id: GO:0015674 alt_id: GO:0072512 def: "The directed movement of a monoatomic cation, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monatomic cations (also called simple cations) are positively charged ions consisting of exactly one atom." [GOC:ai] synonym: "cation transport" BROAD [] synonym: "di-, tri-valent inorganic cation transport" NARROW [GOC:mah] synonym: "trivalent inorganic cation transport" NARROW [] is_a: GO:0006811 ! monoatomic ion transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:23906 ! monoatomic cation relationship: has_primary_input CHEBI:23906 ! monoatomic cation [Term] id: GO:0006814 name: sodium ion transport namespace: biological_process alt_id: GO:0006834 alt_id: GO:0016974 def: "The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "mitochondrial sodium/calcium ion exchange" NARROW [] synonym: "sodium channel auxiliary protein activity" RELATED [GOC:mah] synonym: "sodium transport" EXACT [] synonym: "sodium/potassium transport" BROAD [] synonym: "sodium:calcium exchange" NARROW [] synonym: "sodium:solute transport" NARROW [] is_a: GO:0030001 ! metal ion transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:29101 ! sodium(1+) relationship: has_primary_input CHEBI:29101 ! sodium(1+) [Term] id: GO:0006817 name: phosphate ion transport namespace: biological_process def: "The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] synonym: "phosphate transport" RELATED [] is_a: GO:0015698 ! inorganic anion transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:35780 ! phosphate ion relationship: has_primary_input CHEBI:35780 ! phosphate ion [Term] id: GO:0006835 name: dicarboxylic acid transport namespace: biological_process alt_id: GO:0006841 def: "The directed movement of dicarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] synonym: "sodium:dicarboxylate transport" RELATED [] is_a: GO:0046942 ! carboxylic acid transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:35693 ! dicarboxylic acid anion relationship: has_primary_input CHEBI:35693 ! dicarboxylic acid anion [Term] id: GO:0006836 name: neurotransmitter transport namespace: biological_process def: "The directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell." [GOC:ai] subset: goslim_pir synonym: "sodium:neurotransmitter transport" NARROW [] is_a: GO:0006810 ! transport relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa [Term] id: GO:0006837 name: serotonin transport namespace: biological_process def: "The directed movement of serotonin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems." [GOC:ai] is_a: GO:0071705 ! nitrogen compound transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:350546 ! serotonin(1+) relationship: has_primary_input CHEBI:350546 ! serotonin(1+) [Term] id: GO:0006846 name: acetate transport namespace: biological_process def: "The directed movement of acetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] is_a: GO:0015718 ! monocarboxylic acid transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:30089 ! acetate relationship: has_primary_input CHEBI:30089 ! acetate [Term] id: GO:0006847 name: plasma membrane acetate transport namespace: biological_process def: "The directed movement of acetate across a plasma membrane." [GOC:ai] is_a: GO:0035433 ! acetate transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:30089 ! acetate intersection_of: results_in_transport_across GO:0005886 ! plasma membrane relationship: results_in_transport_across GO:0005886 ! plasma membrane [Term] id: GO:0006858 name: extracellular transport namespace: biological_process def: "The transport of substances that occurs outside cells." [GOC:go_curators] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: occurs_in GO:0005576 ! extracellular region relationship: occurs_in GO:0005576 ! extracellular region [Term] id: GO:0006860 name: extracellular amino acid transport namespace: biological_process def: "The directed extracellular movement of amino acids." [GOC:ai] is_a: GO:0006858 ! extracellular transport is_a: GO:0006865 ! amino acid transport intersection_of: GO:0006865 ! amino acid transport intersection_of: occurs_in GO:0005576 ! extracellular region [Term] id: GO:0006865 name: amino acid transport namespace: biological_process alt_id: GO:0006866 def: "The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] subset: goslim_pir subset: goslim_yeast is_a: GO:0015849 ! organic acid transport is_a: GO:0071705 ! nitrogen compound transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:33709 ! amino acid relationship: has_primary_input CHEBI:33709 ! amino acid [Term] id: GO:0006869 name: lipid transport namespace: biological_process def: "The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent." [ISBN:0198506732] subset: goslim_drosophila subset: goslim_pir subset: goslim_yeast is_a: GO:0071702 ! organic substance transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:18059 ! lipid relationship: has_primary_input CHEBI:18059 ! lipid relationship: part_of GO:0010876 ! lipid localization [Term] id: GO:0006886 name: intracellular protein transport namespace: biological_process alt_id: GO:0032779 def: "The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell." [GOC:mah] subset: goslim_generic subset: goslim_prokaryote synonym: "copper-induced intracellular protein transport" RELATED [GOC:al] is_a: GO:0015031 ! protein transport is_a: GO:0046907 ! intracellular transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input PR:000000001 ! protein intersection_of: occurs_in GO:0005622 ! intracellular anatomical structure relationship: part_of GO:0008104 ! protein localization [Term] id: GO:0006887 name: exocytosis namespace: biological_process alt_id: GO:0016194 alt_id: GO:0016195 def: "A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell." [GOC:mah, ISBN:0716731363, PMID:22323285] subset: goslim_yeast synonym: "nonselective vesicle exocytosis" RELATED [] synonym: "vesicle exocytosis" EXACT [] xref: Wikipedia:Exocytosis is_a: GO:0016192 ! vesicle-mediated transport is_a: GO:0032940 ! secretion by cell intersection_of: GO:0006810 ! transport intersection_of: process_has_causal_agent GO:0070382 ! exocytic vesicle relationship: has_part GO:0099500 ! vesicle fusion to plasma membrane relationship: process_has_causal_agent GO:0070382 ! exocytic vesicle [Term] id: GO:0006892 name: post-Golgi vesicle-mediated transport namespace: biological_process def: "The directed movement of substances from the Golgi to other parts of the cell, including organelles and the plasma membrane, mediated by small transport vesicles." [GOC:ai, GOC:mah] synonym: "post-Golgi transport" EXACT [] is_a: GO:0048193 ! Golgi vesicle transport [Term] id: GO:0006893 name: Golgi to plasma membrane transport namespace: biological_process def: "The directed movement of substances from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane, where they fuse and release their contents by exocytosis." [ISBN:0716731363] synonym: "Golgi to plasma membrane vesicle-mediated transport" EXACT [] is_a: GO:0006892 ! post-Golgi vesicle-mediated transport is_a: GO:0098876 ! vesicle-mediated transport to the plasma membrane intersection_of: GO:0016192 ! vesicle-mediated transport intersection_of: has_target_end_location GO:0005886 ! plasma membrane intersection_of: has_target_start_location GO:0005794 ! Golgi apparatus relationship: has_target_start_location GO:0005794 ! Golgi apparatus [Term] id: GO:0006896 name: Golgi to vacuole transport namespace: biological_process def: "The directed movement of substances from the Golgi to the vacuole." [GOC:ai] synonym: "Golgi to vacuole vesicle-mediated transport" EXACT [] is_a: GO:0006892 ! post-Golgi vesicle-mediated transport is_a: GO:0007034 ! vacuolar transport intersection_of: GO:0016192 ! vesicle-mediated transport intersection_of: has_target_end_location GO:0005773 ! vacuole intersection_of: has_target_start_location GO:0005794 ! Golgi apparatus intersection_of: occurs_in GO:0005622 ! intracellular anatomical structure relationship: has_target_end_location GO:0005773 ! vacuole relationship: has_target_start_location GO:0005794 ! Golgi apparatus [Term] id: GO:0006897 name: endocytosis namespace: biological_process alt_id: GO:0016193 alt_id: GO:0016196 alt_id: GO:0098701 def: "A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a part of the plasma membrane to form a new membrane-bounded vesicle." [GOC:mah, ISBN:0198506732, ISBN:0716731363, Wikipedia:Endocytosis] subset: goslim_yeast synonym: "endocytic import into cell" EXACT [] synonym: "nonselective vesicle endocytosis" RELATED [] synonym: "plasma membrane invagination" NARROW [] synonym: "vesicle endocytosis" EXACT [] xref: Wikipedia:Endocytosis is_a: GO:0016192 ! vesicle-mediated transport is_a: GO:0098657 ! import into cell relationship: has_part GO:0006900 ! vesicle budding from membrane relationship: has_part GO:0010324 ! membrane invagination relationship: has_target_end_location GO:0031410 ! cytoplasmic vesicle property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24907" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/25268" xsd:anyURI [Term] id: GO:0006900 name: vesicle budding from membrane namespace: biological_process alt_id: GO:0006902 alt_id: GO:1902591 def: "The evagination of a membrane, resulting in formation of a vesicle." [GOC:jid, GOC:tb] synonym: "membrane evagination" EXACT [] synonym: "nonselective vesicle assembly" RELATED [] synonym: "single organism membrane budding" RELATED [GOC:TermGenie] synonym: "single-organism membrane budding" RELATED [] synonym: "vesicle biosynthesis" EXACT [] synonym: "vesicle budding" RELATED [] synonym: "vesicle formation" EXACT [] is_a: GO:0016050 ! vesicle organization is_a: GO:0061024 ! membrane organization relationship: part_of GO:0016192 ! vesicle-mediated transport created_by: jl creation_date: 2013-12-19T15:26:17Z [Term] id: GO:0006903 name: vesicle targeting namespace: biological_process def: "The process in which vesicles are directed to specific destination membranes. Targeting involves coordinated interactions among cytoskeletal elements (microtubules or actin filaments), motor proteins, molecules at the vesicle membrane and target membrane surfaces, and vesicle cargo." [GOC:mah, PMID:17335816] is_a: GO:0009987 ! cellular process relationship: part_of GO:0016192 ! vesicle-mediated transport relationship: part_of GO:0051650 ! establishment of vesicle localization [Term] id: GO:0006906 name: vesicle fusion namespace: biological_process def: "Fusion of the membrane of a transport vesicle with its target membrane." [GOC:jid] is_a: GO:0016050 ! vesicle organization is_a: GO:0090174 ! organelle membrane fusion intersection_of: GO:0009987 ! cellular process intersection_of: results_in_fusion_of GO:0012506 ! vesicle membrane relationship: part_of GO:0016192 ! vesicle-mediated transport relationship: results_in_fusion_of GO:0012506 ! vesicle membrane [Term] id: GO:0006909 name: phagocytosis namespace: biological_process def: "A vesicle-mediated transport process that results in the engulfment of external particulate material by phagocytes and their delivery to the lysosome. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles." [ISBN:0198506732] xref: Wikipedia:Phagocytosis is_a: GO:0006897 ! endocytosis property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24907" xsd:anyURI property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0006915 name: apoptotic process namespace: biological_process alt_id: GO:0006917 alt_id: GO:0008632 def: "A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died." [GOC:cjm, GOC:dhl, GOC:ecd, GOC:go_curators, GOC:mtg_apoptosis, GOC:tb, ISBN:0198506732, PMID:18846107, PMID:21494263] synonym: "activation of apoptosis" NARROW [] synonym: "apoptosis" NARROW [] synonym: "apoptosis activator activity" RELATED [] synonym: "apoptosis signaling" NARROW [] synonym: "apoptotic cell death" EXACT [GOC:sl] synonym: "apoptotic program" NARROW [GOC:add] synonym: "apoptotic programmed cell death" EXACT [] synonym: "caspase-dependent programmed cell death" RELATED [] synonym: "cell suicide" BROAD [] synonym: "cellular suicide" BROAD [] synonym: "commitment to apoptosis" RELATED [] synonym: "induction of apoptosis" RELATED [] synonym: "induction of apoptosis by p53" RELATED [] synonym: "programmed cell death by apoptosis" EXACT [] synonym: "signaling (initiator) caspase activity" RELATED [] synonym: "type I programmed cell death" NARROW [] xref: Wikipedia:Apoptosis is_a: GO:0012501 ! programmed cell death relationship: ends_with GO:0097194 ! execution phase of apoptosis relationship: in_taxon NCBITaxon:33154 {all_only="true"} ! Opisthokonta relationship: only_in_taxon NCBITaxon:33154 ! Opisthokonta relationship: starts_with GO:0097190 ! apoptotic signaling pathway property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:4896 [Term] id: GO:0006921 name: cellular component disassembly involved in execution phase of apoptosis namespace: biological_process def: "The breakdown of structures such as organelles, proteins, or other macromolecular structures during apoptosis." [GOC:dph, GOC:mah, GOC:mtg_apoptosis, GOC:tb] synonym: "cellular component disassembly involved in apoptosis" NARROW [] synonym: "cellular component disassembly involved in apoptotic process" BROAD [] synonym: "disassembly of cell structures" BROAD [] is_a: GO:0022411 ! cellular component disassembly intersection_of: GO:0022411 ! cellular component disassembly intersection_of: part_of GO:0097194 ! execution phase of apoptosis relationship: part_of GO:0097194 ! execution phase of apoptosis [Term] id: GO:0006936 name: muscle contraction namespace: biological_process def: "A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis." [GOC:ef, GOC:mtg_muscle, ISBN:0198506732] subset: goslim_pir xref: Wikipedia:Muscle_contraction is_a: GO:0003012 ! muscle system process relationship: occurs_in UBERON:0002385 ! muscle tissue [Term] id: GO:0006937 name: regulation of muscle contraction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of muscle contraction." [GOC:go_curators] is_a: GO:0090257 ! regulation of muscle system process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006936 ! muscle contraction relationship: regulates GO:0006936 ! muscle contraction [Term] id: GO:0006939 name: smooth muscle contraction namespace: biological_process def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length." [GOC:ef, GOC:jl, GOC:mtg_muscle, ISBN:0198506732] synonym: "visceral muscle contraction" EXACT [] is_a: GO:0006936 ! muscle contraction intersection_of: GO:0006936 ! muscle contraction intersection_of: occurs_in UBERON:0001135 ! smooth muscle tissue relationship: occurs_in UBERON:0001135 ! smooth muscle tissue [Term] id: GO:0006940 name: regulation of smooth muscle contraction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of smooth muscle contraction." [GOC:go_curators] is_a: GO:0006937 ! regulation of muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006939 ! smooth muscle contraction relationship: regulates GO:0006939 ! smooth muscle contraction [Term] id: GO:0006941 name: striated muscle contraction namespace: biological_process def: "A process in which force is generated within striated muscle tissue, resulting in the shortening of the muscle. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Striated muscle is a type of muscle in which the repeating units (sarcomeres) of the contractile myofibrils are arranged in registry throughout the cell, resulting in transverse or oblique striations observable at the level of the light microscope." [GOC:jl, GOC:mtg_muscle, ISBN:0198506732] synonym: "sarcomeric muscle contraction" EXACT [] is_a: GO:0006936 ! muscle contraction relationship: occurs_in UBERON:0002036 ! striated muscle tissue [Term] id: GO:0006942 name: regulation of striated muscle contraction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of striated muscle contraction." [GOC:go_curators] is_a: GO:0006937 ! regulation of muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006941 ! striated muscle contraction relationship: regulates GO:0006941 ! striated muscle contraction [Term] id: GO:0006949 name: syncytium formation namespace: biological_process def: "The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane. Syncytia are normally derived from single cells that fuse or fail to complete cell division." [ISBN:0198506732] subset: goslim_pir is_a: GO:0009987 ! cellular process is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity CL:0000228 ! multinucleate cell relationship: results_in_formation_of_anatomical_entity CL:0000228 ! multinucleate cell [Term] id: GO:0006950 name: response to stress namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." [GOC:mah] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_manually_annotate subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_metagenomics subset: goslim_plant synonym: "response to abiotic stress" RELATED [] synonym: "response to biotic stress" RELATED [] is_a: GO:0050896 ! response to stimulus [Term] id: GO:0006952 name: defense response namespace: biological_process alt_id: GO:0002217 alt_id: GO:0042829 def: "Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack." [GOC:go_curators] synonym: "antimicrobial peptide activity" RELATED [] synonym: "defence response" EXACT [] synonym: "defense/immunity protein activity" RELATED [] synonym: "physiological defense response" EXACT [] is_a: GO:0006950 ! response to stress [Term] id: GO:0006954 name: inflammatory response namespace: biological_process def: "The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages." [GO_REF:0000022, ISBN:0198506732] subset: goslim_generic synonym: "inflammation" BROAD [] xref: Wikipedia:Inflammation is_a: GO:0006952 ! defense response relationship: in_taxon NCBITaxon:7742 {all_only="true"} ! Vertebrata relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata [Term] id: GO:0006955 name: immune response namespace: biological_process def: "Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat." [GO_REF:0000022, GOC:add] subset: goslim_drosophila is_a: GO:0002376 ! immune system process is_a: GO:0050896 ! response to stimulus [Term] id: GO:0006996 name: organelle organization namespace: biological_process alt_id: GO:1902589 def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane." [GOC:mah] subset: goslim_candida subset: goslim_pir synonym: "organelle organisation" EXACT [] synonym: "organelle organization and biogenesis" RELATED [GOC:dph, GOC:jl, GOC:mah] synonym: "single organism organelle organization" EXACT [GOC:TermGenie] synonym: "single-organism organelle organization" RELATED [] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0043226 ! organelle relationship: results_in_organization_of GO:0043226 ! organelle created_by: jl creation_date: 2013-12-19T15:25:51Z [Term] id: GO:0006997 name: nucleus organization namespace: biological_process alt_id: GO:0048287 def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus." [GOC:dph, GOC:ems, GOC:jl, GOC:mah] subset: goslim_candida subset: goslim_drosophila subset: goslim_pir subset: goslim_yeast synonym: "nuclear morphology" RELATED [] synonym: "nuclear organisation" EXACT [] synonym: "nuclear organization" EXACT [] synonym: "nuclear organization and biogenesis" RELATED [GOC:mah] synonym: "nucleus organization and biogenesis" RELATED [GOC:mah] is_a: GO:0006996 ! organelle organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0005634 ! nucleus relationship: results_in_organization_of GO:0005634 ! nucleus [Term] id: GO:0006998 name: nuclear envelope organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope." [GOC:dph, GOC:ems, GOC:jl, GOC:mah] synonym: "nuclear envelope organisation" EXACT [GOC:mah] synonym: "nuclear envelope organization and biogenesis" RELATED [GOC:mah] is_a: GO:0061024 ! membrane organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0005635 ! nuclear envelope relationship: part_of GO:0006997 ! nucleus organization relationship: part_of GO:0010256 ! endomembrane system organization relationship: results_in_organization_of GO:0005635 ! nuclear envelope [Term] id: GO:0007000 name: nucleolus organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleolus." [GOC:dph, GOC:jid, GOC:jl, GOC:mah] synonym: "nucleolus organisation" EXACT [] synonym: "nucleolus organization and biogenesis" RELATED [GOC:mah] is_a: GO:0006997 ! nucleus organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0005730 ! nucleolus relationship: results_in_organization_of GO:0005730 ! nucleolus [Term] id: GO:0007009 name: plasma membrane organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane." [GOC:dph, GOC:jl, GOC:mah] subset: goslim_chembl synonym: "plasma membrane organisation" EXACT [] synonym: "plasma membrane organization and biogenesis" RELATED [GOC:mah] is_a: GO:0061024 ! membrane organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0005886 ! plasma membrane relationship: part_of GO:0010256 ! endomembrane system organization relationship: results_in_organization_of GO:0005886 ! plasma membrane [Term] id: GO:0007010 name: cytoskeleton organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures." [GOC:dph, GOC:jl, GOC:mah] subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_prokaryote subset: goslim_yeast synonym: "cytoskeletal organization and biogenesis" RELATED [GOC:mah] synonym: "cytoskeletal regulator activity" RELATED [] synonym: "cytoskeleton organisation" EXACT [] synonym: "cytoskeleton organization and biogenesis" RELATED [GOC:mah] is_a: GO:0006996 ! organelle organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0005856 ! cytoskeleton relationship: results_in_organization_of GO:0005856 ! cytoskeleton [Term] id: GO:0007015 name: actin filament organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking." [GOC:mah] synonym: "actin filament organisation" EXACT [] synonym: "regulation of actin filament localization" NARROW [] is_a: GO:0097435 ! supramolecular fiber organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0005884 ! actin filament relationship: part_of GO:0030036 ! actin cytoskeleton organization relationship: results_in_organization_of GO:0005884 ! actin filament [Term] id: GO:0007017 name: microtubule-based process namespace: biological_process def: "Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins." [GOC:mah] subset: goslim_chembl is_a: GO:0009987 ! cellular process intersection_of: GO:0009987 ! cellular process intersection_of: process_has_causal_agent GO:0005874 ! microtubule relationship: process_has_causal_agent GO:0005874 ! microtubule property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19809" xsd:anyURI [Term] id: GO:0007018 name: microtubule-based movement namespace: biological_process def: "A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules." [GOC:cjm, ISBN:0815316194] subset: goslim_drosophila subset: goslim_generic is_a: GO:0007017 ! microtubule-based process [Term] id: GO:0007019 name: microtubule depolymerization namespace: biological_process def: "The removal of tubulin heterodimers from one or both ends of a microtubule." [ISBN:0815316194] synonym: "microtubule catastrophe" NARROW [GOC:dph, GOC:tb] synonym: "microtubule depolymerization during nuclear congression" NARROW [] synonym: "microtubule disassembly" EXACT [] synonym: "microtubule shortening" EXACT [] is_a: GO:0031109 ! microtubule polymerization or depolymerization is_a: GO:0051261 ! protein depolymerization is_a: GO:0097435 ! supramolecular fiber organization intersection_of: GO:0022411 ! cellular component disassembly intersection_of: results_in_disassembly_of GO:0005874 ! microtubule relationship: results_in_disassembly_of GO:0005874 ! microtubule [Term] id: GO:0007020 name: microtubule nucleation namespace: biological_process def: "The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation)." [GOC:go_curators, ISBN:0815316194, PMID:12517712] xref: Wikipedia:Microtubule_nucleation is_a: GO:0000226 ! microtubule cytoskeleton organization relationship: part_of GO:0046785 ! microtubule polymerization [Term] id: GO:0007026 name: negative regulation of microtubule depolymerization namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol." [GOC:mah, ISBN:0815316194] synonym: "down regulation of microtubule depolymerization" EXACT [] synonym: "down-regulation of microtubule depolymerization" EXACT [] synonym: "downregulation of microtubule depolymerization" EXACT [] synonym: "inhibition of microtubule depolymerization" NARROW [] synonym: "microtubule rescue" NARROW [GOC:dph, GOC:tb] synonym: "microtubule stabilization" EXACT [] synonym: "negative regulation of microtubule catastrophe" NARROW [GOC:dph, GOC:tb] synonym: "negative regulation of microtubule disassembly" EXACT [] is_a: GO:0031111 ! negative regulation of microtubule polymerization or depolymerization is_a: GO:0031114 ! regulation of microtubule depolymerization is_a: GO:1901880 ! negative regulation of protein depolymerization is_a: GO:1902904 ! negative regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007019 ! microtubule depolymerization relationship: negatively_regulates GO:0007019 ! microtubule depolymerization [Term] id: GO:0007027 name: negative regulation of axonemal microtubule depolymerization namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the depolymerization of the specialized microtubules of the axoneme." [GOC:dph, GOC:mah] synonym: "axonemal microtubule stabilization" EXACT [] synonym: "negative regulation of microtubule depolymerization in axoneme" RELATED [GOC:dph] is_a: GO:0007026 ! negative regulation of microtubule depolymerization is_a: GO:0010937 ! regulation of cytoplasmic microtubule depolymerization is_a: GO:0031345 ! negative regulation of cell projection organization is_a: GO:0120035 ! regulation of plasma membrane bounded cell projection organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060404 ! axonemal microtubule depolymerization relationship: negatively_regulates GO:0060404 ! axonemal microtubule depolymerization [Term] id: GO:0007028 name: cytoplasm organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cytoplasm. The cytoplasm is all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." [GOC:curators, GOC:dph, GOC:jl, GOC:mah] subset: goslim_pir synonym: "cytoplasm organisation" EXACT [] synonym: "cytoplasm organization and biogenesis" RELATED [GOC:mah] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0005737 ! cytoplasm relationship: results_in_organization_of GO:0005737 ! cytoplasm [Term] id: GO:0007030 name: Golgi organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus." [GOC:dph, GOC:jl, GOC:mah] subset: goslim_pir synonym: "Golgi apparatus organization" EXACT [] synonym: "Golgi organisation" EXACT [] synonym: "Golgi organization and biogenesis" RELATED [GOC:mah] is_a: GO:0006996 ! organelle organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0005794 ! Golgi apparatus relationship: part_of GO:0010256 ! endomembrane system organization relationship: results_in_organization_of GO:0005794 ! Golgi apparatus [Term] id: GO:0007033 name: vacuole organization namespace: biological_process alt_id: GO:0044086 def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole." [GOC:mah] subset: goslim_drosophila subset: goslim_pir subset: goslim_yeast synonym: "vacuolar assembly" NARROW [GOC:mah] synonym: "vacuole biogenesis" RELATED [GOC:mah] synonym: "vacuole organisation" EXACT [] synonym: "vacuole organization and biogenesis" RELATED [GOC:mah] is_a: GO:0006996 ! organelle organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0005773 ! vacuole relationship: results_in_organization_of GO:0005773 ! vacuole [Term] id: GO:0007034 name: vacuolar transport namespace: biological_process def: "The directed movement of substances into, out of or within a vacuole." [GOC:ai] subset: goslim_chembl is_a: GO:0046907 ! intracellular transport intersection_of: GO:0046907 ! intracellular transport intersection_of: results_in_transport_to_from_or_in GO:0005773 ! vacuole relationship: results_in_transport_to_from_or_in GO:0005773 ! vacuole [Term] id: GO:0007039 name: protein catabolic process in the vacuole namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of a protein in the vacuole, usually by the action of vacuolar proteases." [GOC:mah, GOC:vw] synonym: "vacuolar protein breakdown" RELATED [] synonym: "vacuolar protein catabolic process" RELATED [] synonym: "vacuolar protein catabolism" RELATED [] synonym: "vacuolar protein degradation" RELATED [] is_a: GO:0030163 ! protein catabolic process intersection_of: GO:0030163 ! protein catabolic process intersection_of: occurs_in GO:0005773 ! vacuole relationship: occurs_in GO:0005773 ! vacuole [Term] id: GO:0007043 name: cell-cell junction assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form a junction between cells." [GOC:ai] synonym: "intercellular junction assembly" EXACT [] is_a: GO:0034329 ! cell junction assembly is_a: GO:0045216 ! cell-cell junction organization intersection_of: GO:0034329 ! cell junction assembly intersection_of: results_in_assembly_of GO:0005911 ! cell-cell junction relationship: results_in_assembly_of GO:0005911 ! cell-cell junction [Term] id: GO:0007049 name: cell cycle namespace: biological_process def: "The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division." [GOC:go_curators, GOC:mtg_cell_cycle] subset: gocheck_do_not_manually_annotate subset: goslim_agr subset: goslim_candida subset: goslim_chembl subset: goslim_flybase_ribbon subset: goslim_pir subset: goslim_plant synonym: "cell-division cycle" EXACT [] xref: Wikipedia:Cell_cycle is_a: GO:0009987 ! cellular process [Term] id: GO:0007059 name: chromosome segregation namespace: biological_process def: "The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles." [GOC:jl, GOC:mah, GOC:mtg_cell_cycle, GOC:vw] subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_pir subset: goslim_prokaryote subset: goslim_yeast synonym: "chromosome division" EXACT [] synonym: "chromosome transmission" RELATED [] xref: Wikipedia:Chromosome_segregation is_a: GO:0022402 ! cell cycle process [Term] id: GO:0007076 name: mitotic chromosome condensation namespace: biological_process def: "The cell cycle process in which chromatin structure is compacted prior to and during mitosis in eukaryotic cells." [GOC:mah, ISBN:0815316194] is_a: GO:0030261 ! chromosome condensation is_a: GO:1903047 ! mitotic cell cycle process intersection_of: GO:0030261 ! chromosome condensation intersection_of: part_of GO:0000278 ! mitotic cell cycle relationship: part_of GO:0000070 ! mitotic sister chromatid segregation [Term] id: GO:0007077 name: mitotic nuclear membrane disassembly namespace: biological_process def: "The mitotic cell cycle process in which the controlled partial or complete breakdown of the nuclear membranes during occurs during mitosis." [GOC:bf, PMID:32848252] synonym: "local NEB" BROAD [] synonym: "mitotic nuclear envelope breakdown" EXACT [] synonym: "mitotic nuclear envelope catabolism" RELATED [] synonym: "mitotic nuclear envelope degradation" RELATED [] synonym: "mitotic nuclear envelope disassembly" RELATED [] synonym: "NEB" BROAD [] synonym: "nuclear envelope breakdown" BROAD [] is_a: GO:0051081 ! nuclear membrane disassembly is_a: GO:1903047 ! mitotic cell cycle process intersection_of: GO:0051081 ! nuclear membrane disassembly intersection_of: part_of GO:0000278 ! mitotic cell cycle [Term] id: GO:0007088 name: regulation of mitotic nuclear division namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mitosis." [GOC:go_curators] synonym: "regulation of mitosis" EXACT [] is_a: GO:0007346 ! regulation of mitotic cell cycle is_a: GO:0010564 ! regulation of cell cycle process is_a: GO:0051783 ! regulation of nuclear division intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0140014 ! mitotic nuclear division relationship: regulates GO:0140014 ! mitotic nuclear division [Term] id: GO:0007097 name: nuclear migration namespace: biological_process alt_id: GO:0040023 def: "The directed movement of the nucleus to a specific location within a cell." [GOC:ai] synonym: "establishment of cell nucleus localization" RELATED [] synonym: "establishment of localization of nucleus" RELATED [] synonym: "establishment of nucleus localisation" RELATED [GOC:mah] synonym: "establishment of nucleus localization" RELATED [] synonym: "establishment of position of nucleus" EXACT [] synonym: "nuclear movement" EXACT [] synonym: "nuclear positioning" EXACT [] synonym: "nucleus migration" EXACT [] synonym: "nucleus positioning" EXACT [] synonym: "positioning of nucleus" EXACT [] is_a: GO:0046907 ! intracellular transport is_a: GO:0051647 ! nucleus localization is_a: GO:0051656 ! establishment of organelle localization intersection_of: GO:0046907 ! intracellular transport intersection_of: has_primary_input GO:0005634 ! nucleus [Term] id: GO:0007113 name: endomitotic cell cycle namespace: biological_process def: "A mitotic cell cycle in which chromosomes are replicated and sister chromatids separate, but spindle formation, nuclear membrane breakdown and nuclear division do not occur, resulting in an increased number of chromosomes in the cell." [GOC:curators, GOC:dos, GOC:expert_vm] comment: Note that this term should not be confused with 'abortive mitotic cell cycle ; GO:0033277'. Although abortive mitosis is sometimes called endomitosis, GO:0033277 refers to a process in which a mitotic spindle forms and chromosome separation begins. synonym: "endomitosis" RELATED [] xref: Wikipedia:Mitosis#Endomitosis is_a: GO:0000278 ! mitotic cell cycle [Term] id: GO:0007135 name: meiosis II namespace: biological_process def: "The second nuclear division of meiosis, in which the two chromatids in each chromosome are separated, resulting in four daughter nuclei from the two nuclei produced in meiosis II." [GOC:dph, GOC:mah, ISBN:0198547684] synonym: "meiosis II nuclear division" EXACT [] xref: Wikipedia:Meiosis#Meiosis_II is_a: GO:0061983 ! meiosis II cell cycle process is_a: GO:0140013 ! meiotic nuclear division [Term] id: GO:0007140 name: male meiotic nuclear division namespace: biological_process def: "A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline." [GOC:dph, GOC:mah, GOC:vw] synonym: "male meiosis" RELATED [] synonym: "male nuclear division" BROAD [] is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0140013 ! meiotic nuclear division intersection_of: GO:0000280 ! nuclear division intersection_of: part_of GO:0048232 ! male gamete generation intersection_of: part_of GO:0051321 ! meiotic cell cycle relationship: part_of GO:0048232 ! male gamete generation property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0007142 name: male meiosis II namespace: biological_process def: "A cell cycle process comprising the steps by which a cell progresses through male meiosis II, the second meiotic division in the male germline." [GOC:dph, GOC:mah] synonym: "male meiosis II nuclear division" EXACT [] is_a: GO:0007135 ! meiosis II is_a: GO:0007140 ! male meiotic nuclear division intersection_of: GO:0007135 ! meiosis II intersection_of: part_of GO:0048232 ! male gamete generation intersection_of: part_of GO:0051321 ! meiotic cell cycle [Term] id: GO:0007143 name: female meiotic nuclear division namespace: biological_process def: "A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline." [GOC:dph, GOC:ems, GOC:mah, GOC:vw] comment: Note that female germ lines can be found in female or hermaphroditic organisms, so this term can be used to annotate gene products from hermaphrodites such as those of C. elegans. See also the biological process term 'meiotic nuclear division; GO:0140013'. synonym: "female meiosis" BROAD [] synonym: "female meiotic division" BROAD [] is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0140013 ! meiotic nuclear division intersection_of: GO:0000280 ! nuclear division intersection_of: part_of GO:0007292 ! female gamete generation intersection_of: part_of GO:0051321 ! meiotic cell cycle relationship: part_of GO:0007292 ! female gamete generation property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0007147 name: female meiosis II namespace: biological_process def: "The cell cycle process in which the second meiotic division occurs in the female germline." [GOC:mah] synonym: "female meiosis II nuclear division" EXACT [] is_a: GO:0007135 ! meiosis II is_a: GO:0007143 ! female meiotic nuclear division intersection_of: GO:0007135 ! meiosis II intersection_of: part_of GO:0007292 ! female gamete generation intersection_of: part_of GO:0051321 ! meiotic cell cycle [Term] id: GO:0007154 name: cell communication namespace: biological_process def: "Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:mah] subset: goslim_pir subset: goslim_plant xref: Wikipedia:Cell_signaling is_a: GO:0009987 ! cellular process [Term] id: GO:0007155 name: cell adhesion namespace: biological_process alt_id: GO:0098602 def: "The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules." [GOC:hb, GOC:pf] subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir subset: goslim_pombe subset: goslim_prokaryote synonym: "cell adhesion molecule activity" RELATED [] synonym: "single organism cell adhesion" RELATED [] xref: Wikipedia:Cell_adhesion is_a: GO:0009987 ! cellular process created_by: dos creation_date: 2014-04-15T15:59:10Z [Term] id: GO:0007159 name: leukocyte cell-cell adhesion namespace: biological_process def: "The attachment of a leukocyte to another cell via adhesion molecules." [GOC:go_curators] synonym: "leukocyte adhesion" EXACT [] synonym: "leukocyte cell adhesion" EXACT [] is_a: GO:0098609 ! cell-cell adhesion intersection_of: GO:0098609 ! cell-cell adhesion intersection_of: has_participant CL:0000738 ! leukocyte relationship: has_participant CL:0000738 ! leukocyte relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: in_taxon NCBITaxon:7742 {all_only="true"} ! Vertebrata relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata [Term] id: GO:0007162 name: negative regulation of cell adhesion namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion." [GOC:go_curators] synonym: "cell adhesion receptor inhibitor activity" RELATED [] synonym: "down regulation of cell adhesion" EXACT [] synonym: "down-regulation of cell adhesion" EXACT [] synonym: "downregulation of cell adhesion" EXACT [] synonym: "inhibition of cell adhesion" NARROW [] is_a: GO:0030155 ! regulation of cell adhesion is_a: GO:0048523 ! negative regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007155 ! cell adhesion relationship: negatively_regulates GO:0007155 ! cell adhesion [Term] id: GO:0007163 name: establishment or maintenance of cell polarity namespace: biological_process alt_id: GO:0030012 alt_id: GO:0030467 def: "Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns." [GOC:mah] subset: goslim_drosophila subset: goslim_generic subset: goslim_pombe subset: goslim_prokaryote synonym: "cell polarity" RELATED [GOC:mah, GOC:vw] synonym: "establishment and/or maintenance of cell polarity" RELATED [] synonym: "establishment and/or maintenance of cell polarization" RELATED [] is_a: GO:0009987 ! cellular process [Term] id: GO:0007165 name: signal transduction namespace: biological_process alt_id: GO:0023014 alt_id: GO:0023015 alt_id: GO:0023016 alt_id: GO:0023033 alt_id: GO:0023045 def: "The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell." [GOC:go_curators, GOC:mtg_signaling_feb11] comment: Note that signal transduction is defined broadly to include a ligand interacting with a receptor, downstream signaling steps and a response being triggered. A change in form of the signal in every step is not necessary. Note that in many cases the end of this process is regulation of the initiation of transcription. Note that specific transcription factors may be annotated to this term, but core/general transcription machinery such as RNA polymerase should not. subset: goslim_candida subset: goslim_chembl subset: goslim_metagenomics subset: goslim_plant synonym: "signal transduction by cis-phosphorylation" NARROW [] synonym: "signal transduction by conformational transition" NARROW [] synonym: "signal transduction by protein phosphorylation" NARROW [] synonym: "signal transduction by trans-phosphorylation" NARROW [] synonym: "signaling cascade" NARROW [] synonym: "signaling pathway" RELATED [] synonym: "signalling cascade" NARROW [] synonym: "signalling pathway" RELATED [GOC:mah] xref: Wikipedia:Signal_transduction is_a: GO:0009987 ! cellular process is_a: GO:0050794 ! regulation of cellular process relationship: part_of GO:0007154 ! cell communication relationship: part_of GO:0023052 ! signaling relationship: part_of GO:0051716 ! cellular response to stimulus [Term] id: GO:0007267 name: cell-cell signaling namespace: biological_process def: "Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions." [GOC:dos, GOC:mah] subset: goslim_chembl subset: goslim_plant synonym: "cell-cell signalling" EXACT [] is_a: GO:0007154 ! cell communication is_a: GO:0023052 ! signaling [Term] id: GO:0007268 name: chemical synaptic transmission namespace: biological_process def: "The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse." [GOC:jl, MeSH:D009435] subset: goslim_synapse synonym: "neurotransmission" RELATED [GOC:dph] synonym: "signal transmission across a synapse" BROAD [] synonym: "synaptic transmission" BROAD [] xref: Wikipedia:Neurotransmission is_a: GO:0098916 ! anterograde trans-synaptic signaling relationship: has_participant GO:0045202 ! synapse [Term] id: GO:0007269 name: neurotransmitter secretion namespace: biological_process alt_id: GO:0010554 def: "The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium-regulated exocytosis during synaptic transmission." [GOC:dph] comment: A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma-aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin. subset: goslim_synapse synonym: "neurotransmitter release" EXACT [] synonym: "neurotransmitter secretory pathway" EXACT [] is_a: GO:0006836 ! neurotransmitter transport is_a: GO:0051649 ! establishment of localization in cell is_a: GO:0099643 ! signal release from synapse relationship: occurs_in GO:0098793 ! presynapse [Term] id: GO:0007271 name: synaptic transmission, cholinergic namespace: biological_process def: "The vesicular release of acetylcholine from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse." [GOC:dos, Wikipedia:Cholinergic] synonym: "cholinergic synaptic transmission" EXACT [] is_a: GO:0007268 ! chemical synaptic transmission relationship: has_participant CHEBI:15355 ! acetylcholine [Term] id: GO:0007274 name: neuromuscular synaptic transmission namespace: biological_process def: "The process of synaptic transmission from a neuron to a muscle, across a synapse." [GOC:dos, GOC:jl, MeSH:D009435] is_a: GO:0007268 ! chemical synaptic transmission [Term] id: GO:0007275 name: multicellular organism development namespace: biological_process def: "The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." [GOC:dph, GOC:ems, GOC:isa_complete, GOC:tb] comment: Note that this term was 'developmental process'. subset: gocheck_do_not_annotate subset: goslim_chembl subset: goslim_plant is_a: GO:0032501 ! multicellular organismal process is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_developmental_progression_of UBERON:0000468 ! multicellular organism relationship: results_in_developmental_progression_of UBERON:0000468 ! multicellular organism property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/21234" xsd:anyURI [Term] id: GO:0007276 name: gamete generation namespace: biological_process alt_id: GO:0009552 def: "The generation and maintenance of gametes in a multicellular organism. A gamete is a haploid reproductive cell." [GOC:ems, GOC:mtg_sensu] synonym: "gametogenesis" RELATED [] is_a: GO:0048609 ! multicellular organismal reproductive process relationship: part_of GO:0019953 ! sexual reproduction property_value: RO:0002161 NCBITaxon_Union:0000023 [Term] id: GO:0007281 name: germ cell development namespace: biological_process def: "The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism." [GOC:go_curators] synonym: "gametogenesis" NARROW [] synonym: "germ-cell development" EXACT [] synonym: "primordial germ cell development" NARROW [] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000586 ! germ cell relationship: part_of GO:0007276 ! gamete generation relationship: results_in_development_of CL:0000586 ! germ cell [Term] id: GO:0007283 name: spermatogenesis namespace: biological_process def: "The developmental process by which male germ line stem cells self renew or give rise to successive cell types resulting in the development of a spermatozoa." [GOC:jid, ISBN:9780878933846, PMID:28073824, PMID:30990821] synonym: "generation of spermatozoa" EXACT systematic_synonym [] xref: Wikipedia:Spermatogenesis is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0048232 ! male gamete generation [Term] id: GO:0007284 name: spermatogonial cell division namespace: biological_process def: "The mitotic divisions of the primary spermatogonial cell (a primordial male germ cell) to form secondary spermatogonia (primary spermatocytes)." [GOC:bf, GOC:pr, ISBN:0879694238] comment: See also the Cell Ontology terms 'spermatogonium ; CL:0000020' and 'primary spermatocyte ; CL:0000656'. synonym: "spermatogonium division" EXACT [] is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0051301 ! cell division intersection_of: GO:0051301 ! cell division intersection_of: has_primary_input CL:0000020 ! spermatogonium relationship: has_primary_input CL:0000020 ! spermatogonium relationship: part_of GO:0007283 ! spermatogenesis [Term] id: GO:0007285 name: primary spermatocyte growth namespace: biological_process def: "The phase of growth and gene expression that male germ cells undergo as they enter the spermatocyte stage. The cells grow in volume and transcribe most of the gene products needed for the morphological events that follow meiosis." [GOC:jid, ISBN:0879694238] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0048588 ! developmental cell growth intersection_of: GO:0040007 ! growth intersection_of: results_in_growth_of CL:0000656 ! primary spermatocyte relationship: part_of GO:0007283 ! spermatogenesis relationship: results_in_growth_of CL:0000656 ! primary spermatocyte [Term] id: GO:0007286 name: spermatid development namespace: biological_process def: "The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure." [GOC:dph, GOC:go_curators] synonym: "spermatid cell development" EXACT [] synonym: "spermiogenesis" EXACT [] xref: Wikipedia:Spermiogenesis is_a: GO:0007281 ! germ cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000018 ! spermatid relationship: part_of GO:0048515 ! spermatid differentiation relationship: results_in_development_of CL:0000018 ! spermatid [Term] id: GO:0007288 name: sperm axoneme assembly namespace: biological_process def: "The assembly and organization of the sperm flagellar axoneme, the bundle of microtubules and associated proteins that forms the core of the eukaryotic sperm flagellum, and is responsible for movement." [GOC:bf, GOC:cilia, ISBN:0198547684] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0035082 ! axoneme assembly intersection_of: GO:0035082 ! axoneme assembly intersection_of: occurs_in CL:0000019 ! sperm relationship: occurs_in CL:0000019 ! sperm relationship: part_of GO:0120316 ! sperm flagellum assembly [Term] id: GO:0007289 name: spermatid nucleus differentiation namespace: biological_process def: "The specialization of the spermatid nucleus during the development of a spermatid into a mature male gamete competent for fertilization." [GOC:bf, GOC:dph, GOC:jl, GOC:mah] comment: See also the Cell Ontology term 'spermatid ; CL:0000018'. synonym: "spermatid nuclear differentiation" EXACT [] is_a: GO:0006997 ! nucleus organization is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism relationship: part_of GO:0007286 ! spermatid development [Term] id: GO:0007292 name: female gamete generation namespace: biological_process def: "Generation of the female gamete; specialised haploid cells produced by meiosis and along with a male gamete takes part in sexual reproduction." [GOC:dph, ISBN:0198506732] is_a: GO:0007276 ! gamete generation [Term] id: GO:0007293 name: germarium-derived egg chamber formation namespace: biological_process def: "Construction of a stage-1 egg chamber in the anterior part of the germarium, from the progeny of germ-line and somatic stem cells. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, ISBN:0879694238] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis relationship: in_taxon NCBITaxon:6656 {all_only="true"} ! Arthropoda relationship: only_in_taxon NCBITaxon:6656 ! Arthropoda relationship: part_of GO:0048477 ! oogenesis [Term] id: GO:0007308 name: oocyte construction namespace: biological_process alt_id: GO:0048110 def: "The synthesis, deposition, and organization of the materials in a cell of an ovary; where the cell can then undergo meiosis and form an ovum. An example of this is found in Drosophila melanogaster." [GOC:dph, GOC:ems, GOC:mtg_sensu, GOC:tb, ISBN:0198506732] synonym: "oocyte arrangement" EXACT [GOC:dph, GOC:tb] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0048469 ! cell maturation intersection_of: GO:0032502 ! developmental process intersection_of: results_in_formation_of_anatomical_entity CL:0000023 ! oocyte relationship: part_of GO:0048599 ! oocyte development relationship: results_in_formation_of_anatomical_entity CL:0000023 ! oocyte [Term] id: GO:0007309 name: oocyte axis specification namespace: biological_process alt_id: GO:0048111 def: "The establishment, maintenance and elaboration of an axis in the oocyte. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, ISBN:0879694238] synonym: "oocyte axis determination" RELATED [] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0009798 ! axis specification intersection_of: GO:0009798 ! axis specification intersection_of: occurs_in CL:0000023 ! oocyte relationship: occurs_in CL:0000023 ! oocyte relationship: part_of GO:0007308 ! oocyte construction [Term] id: GO:0007314 name: oocyte anterior/posterior axis specification namespace: biological_process alt_id: GO:0048112 def: "Polarization of the oocyte along its anterior-posterior axis. An example of this is found in Drosophila melanogaster." [GOC:dph, GOC:mtg_sensu, GOC:tb, ISBN:0879694238] synonym: "oocyte anterior/posterior axis determination" EXACT [GOC:dph, GOC:tb] is_a: GO:0007309 ! oocyte axis specification is_a: GO:0009948 ! anterior/posterior axis specification intersection_of: GO:0009948 ! anterior/posterior axis specification intersection_of: occurs_in CL:0000023 ! oocyte relationship: part_of GO:0008358 ! maternal determination of anterior/posterior axis, embryo [Term] id: GO:0007320 name: insemination namespace: biological_process def: "The introduction of semen or sperm into the genital tract of a female." [ISBN:0582227089] xref: Wikipedia:Insemination is_a: GO:0044703 ! multi-organism reproductive process is_a: GO:0044706 ! multi-multicellular organism process is_a: GO:0048609 ! multicellular organismal reproductive process relationship: part_of GO:0007620 ! copulation [Term] id: GO:0007338 name: single fertilization namespace: biological_process def: "The union of male and female gametes to form a zygote." [GOC:ems, GOC:mtg_sensu] synonym: "zygote biosynthesis" RELATED [] synonym: "zygote formation" RELATED [] is_a: GO:0009566 ! fertilization relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota property_value: RO:0002161 NCBITaxon:58024 [Term] id: GO:0007343 name: egg activation namespace: biological_process def: "The process in which the egg becomes metabolically active, initiates protein and DNA synthesis and undergoes structural changes to its cortex and/or cytoplasm." [GOC:bf, PMID:9630751] xref: Wikipedia:Egg_activation is_a: GO:0001775 ! cell activation is_a: GO:0022414 ! reproductive process intersection_of: GO:0001775 ! cell activation intersection_of: has_primary_input CL:0000025 ! egg cell relationship: has_primary_input CL:0000025 ! egg cell relationship: part_of GO:0007338 ! single fertilization [Term] id: GO:0007346 name: regulation of mitotic cell cycle namespace: biological_process def: "Any process that modulates the rate or extent of progress through the mitotic cell cycle." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "mitotic cell cycle modulation" EXACT [] synonym: "mitotic cell cycle regulation" EXACT [] synonym: "mitotic cell cycle regulator" RELATED [] synonym: "modulation of mitotic cell cycle progression" EXACT [] synonym: "regulation of mitotic cell cycle progression" EXACT [] synonym: "regulation of progression through mitotic cell cycle" EXACT [GOC:dph, GOC:tb] is_a: GO:0051726 ! regulation of cell cycle intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0000278 ! mitotic cell cycle relationship: regulates GO:0000278 ! mitotic cell cycle [Term] id: GO:0007350 name: blastoderm segmentation namespace: biological_process def: "The hierarchical steps resulting in the progressive subdivision of the anterior/posterior axis of the embryo." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238] is_a: GO:0009880 ! embryonic pattern specification is_a: GO:0035282 ! segmentation [Term] id: GO:0007351 name: tripartite regional subdivision namespace: biological_process def: "Subdivision of the embryo along the anterior/posterior axis into anterior, posterior and terminal regions." [GOC:dph, GOC:isa_complete, http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238] is_a: GO:0003002 ! regionalization relationship: part_of GO:0007350 ! blastoderm segmentation [Term] id: GO:0007354 name: zygotic determination of anterior/posterior axis, embryo namespace: biological_process def: "The specification of the anterior/posterior axis of the embryo by products of genes expressed in the zygote; exemplified in insects by the gap genes, pair rule genes and segment polarity gene cascade." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238] is_a: GO:0008595 ! anterior/posterior axis specification, embryo intersection_of: GO:0008595 ! anterior/posterior axis specification, embryo intersection_of: occurs_in CL:0000365 ! animal zygote relationship: occurs_in CL:0000365 ! animal zygote [Term] id: GO:0007369 name: gastrulation namespace: biological_process def: "A complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm." [GOC:curators, ISBN:9780878933846] subset: goslim_drosophila xref: Wikipedia:Gastrulation is_a: GO:0048598 ! embryonic morphogenesis relationship: has_part GO:0001705 ! ectoderm formation relationship: has_part GO:0001706 ! endoderm formation relationship: has_part GO:0001707 ! mesoderm formation [Term] id: GO:0007389 name: pattern specification process namespace: biological_process def: "Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate." [GOC:go_curators, GOC:isa_complete, ISBN:0521436125] subset: goslim_drosophila synonym: "pattern biosynthesis" RELATED [] synonym: "pattern formation" RELATED [] is_a: GO:0032501 ! multicellular organismal process relationship: part_of GO:0007275 ! multicellular organism development [Term] id: GO:0007398 name: ectoderm development namespace: biological_process def: "The process whose specific outcome is the progression of the ectoderm over time, from its formation to the mature structure. In animal embryos, the ectoderm is the outer germ layer of the embryo, formed during gastrulation." [GOC:dph, GOC:tb] is_a: GO:0009888 ! tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000924 ! ectoderm relationship: results_in_development_of UBERON:0000924 ! ectoderm [Term] id: GO:0007399 name: nervous system development namespace: biological_process def: "The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state." [GOC:dgh] subset: goslim_drosophila synonym: "pan-neural process" RELATED [] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001016 ! nervous system relationship: results_in_development_of UBERON:0001016 ! nervous system [Term] id: GO:0007405 name: neuroblast proliferation namespace: biological_process alt_id: GO:0043349 alt_id: GO:0043350 def: "The expansion of a neuroblast population by cell division. A neuroblast is any cell that will divide and give rise to a neuron." [GOC:ai, GOC:mtg_sensu, GOC:sart] is_a: GO:0061351 ! neural precursor cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000031 ! neuroblast (sensu Vertebrata) relationship: acts_on_population_of CL:0000031 ! neuroblast (sensu Vertebrata) relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0048699 ! generation of neurons [Term] id: GO:0007406 name: negative regulation of neuroblast proliferation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the proliferation of neuroblasts." [GOC:ai] synonym: "down regulation of neuroblast proliferation" EXACT [] synonym: "down-regulation of neuroblast proliferation" EXACT [] synonym: "downregulation of neuroblast proliferation" EXACT [] synonym: "inhibition of neuroblast proliferation" NARROW [] synonym: "suppression of neuroblast proliferation" EXACT [] is_a: GO:0050768 ! negative regulation of neurogenesis is_a: GO:1902692 ! regulation of neuroblast proliferation is_a: GO:2000178 ! negative regulation of neural precursor cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007405 ! neuroblast proliferation relationship: negatively_regulates GO:0007405 ! neuroblast proliferation [Term] id: GO:0007407 name: neuroblast activation namespace: biological_process alt_id: GO:0043351 alt_id: GO:0043352 def: "A change in the morphology or behavior of a neuroblast resulting from exposure to an activating factor such as a cellular or soluble ligand." [GOC:go_curators, GOC:mtg_sensu] is_a: GO:0001775 ! cell activation intersection_of: GO:0001775 ! cell activation intersection_of: has_primary_input CL:0000031 ! neuroblast (sensu Vertebrata) relationship: has_primary_input CL:0000031 ! neuroblast (sensu Vertebrata) relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: part_of GO:0048699 ! generation of neurons [Term] id: GO:0007416 name: synapse assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional)." [GOC:mah] subset: goslim_synapse synonym: "synapse biogenesis" EXACT [GOC:mah] synonym: "synaptogenesis" EXACT [GOC:mah] xref: Wikipedia:Synaptogenesis is_a: GO:0034329 ! cell junction assembly is_a: GO:0050808 ! synapse organization intersection_of: GO:0009987 ! cellular process intersection_of: results_in_assembly_of GO:0045202 ! synapse relationship: part_of GO:0007399 ! nervous system development relationship: results_in_assembly_of GO:0045202 ! synapse [Term] id: GO:0007417 name: central nervous system development namespace: biological_process def: "The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord." [GOC:bf, GOC:jid, ISBN:0582227089] synonym: "CNS development" EXACT [] xref: Wikipedia:Neural_development is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001017 ! central nervous system relationship: part_of GO:0007399 ! nervous system development relationship: results_in_development_of UBERON:0001017 ! central nervous system [Term] id: GO:0007420 name: brain development namespace: biological_process def: "The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)." [GOC:dph, GOC:jid, GOC:tb, UBERON:0000955] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000955 ! brain relationship: part_of GO:0007417 ! central nervous system development relationship: part_of GO:0060322 ! head development relationship: results_in_development_of UBERON:0000955 ! brain [Term] id: GO:0007422 name: peripheral nervous system development namespace: biological_process def: "The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands." [GOC:go_curators, UBERON:0000010] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000010 ! peripheral nervous system relationship: part_of GO:0007399 ! nervous system development relationship: results_in_development_of UBERON:0000010 ! peripheral nervous system [Term] id: GO:0007423 name: sensory organ development namespace: biological_process def: "The process whose specific outcome is the progression of sensory organs over time, from its formation to the mature structure." [GOC:go_curators] subset: goslim_drosophila synonym: "sense organ development" EXACT [GOC:dph] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000020 ! sense organ relationship: results_in_development_of UBERON:0000020 ! sense organ [Term] id: GO:0007439 name: ectodermal digestive tract development namespace: biological_process def: "The process whose specific outcome is the progression of the ectodermal digestive tract over time, from its formation to the mature structure. The ectodermal digestive tract includes those portions that are derived from ectoderm." [GOC:curators] synonym: "ectodermal gut development" RELATED [GOC:dph] is_a: GO:0048729 ! tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0004906 ! ectodermal part of digestive tract relationship: part_of GO:0048565 ! digestive tract development relationship: results_in_formation_of_anatomical_entity UBERON:0004906 ! ectodermal part of digestive tract [Term] id: GO:0007440 name: foregut morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the foregut are generated and organized." [GOC:jid] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001041 ! foregut relationship: part_of GO:0048546 ! digestive tract morphogenesis relationship: results_in_morphogenesis_of UBERON:0001041 ! foregut [Term] id: GO:0007442 name: hindgut morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the hindgut are generated and organized." [GOC:jid] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001046 ! hindgut relationship: part_of GO:0048546 ! digestive tract morphogenesis relationship: part_of GO:0061525 ! hindgut development relationship: results_in_morphogenesis_of UBERON:0001046 ! hindgut [Term] id: GO:0007492 name: endoderm development namespace: biological_process def: "The process whose specific outcome is the progression of the endoderm over time, from its formation to the mature structure. The endoderm is the innermost germ layer that develops into the gastrointestinal tract, the lungs and associated tissues." [GOC:dph, GOC:tb] is_a: GO:0009888 ! tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000925 ! endoderm relationship: results_in_development_of UBERON:0000925 ! endoderm [Term] id: GO:0007494 name: midgut development namespace: biological_process def: "The process whose specific outcome is the progression of the midgut over time, from its formation to the mature structure. The midgut is the middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine." [GOC:jid, UBERON:0001045] is_a: GO:0048565 ! digestive tract development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001045 ! midgut relationship: results_in_development_of UBERON:0001045 ! midgut [Term] id: GO:0007498 name: mesoderm development namespace: biological_process def: "The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue." [GOC:dph, GOC:tb] subset: goslim_drosophila is_a: GO:0009888 ! tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000926 ! mesoderm relationship: results_in_development_of UBERON:0000926 ! mesoderm [Term] id: GO:0007506 name: gonadal mesoderm development namespace: biological_process def: "The process whose specific outcome is the progression of the gonadal mesoderm over time, from its formation to the mature structure. The gonadal mesoderm is the middle layer of the three primary germ layers of the embryo which will go on to form the gonads of the organism." [GOC:ai] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0007498 ! mesoderm development is_a: GO:0060485 ! mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003855 ! gonad mesenchyme relationship: part_of GO:0008406 ! gonad development relationship: results_in_development_of UBERON:0003855 ! gonad mesenchyme [Term] id: GO:0007507 name: heart development namespace: biological_process alt_id: GO:0007511 def: "The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood." [GOC:jid, UBERON:0000948] synonym: "cardiac development" RELATED [] synonym: "dorsal vessel development" NARROW [] xref: Wikipedia:Heart_development is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0007100 ! primary circulatory organ relationship: part_of GO:0072359 ! circulatory system development relationship: results_in_development_of UBERON:0007100 ! primary circulatory organ [Term] id: GO:0007517 name: muscle organ development namespace: biological_process def: "The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work." [GOC:jid, ISBN:0198506732] is_a: GO:0048513 ! animal organ development is_a: GO:0061061 ! muscle structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001630 ! muscle organ relationship: results_in_development_of UBERON:0001630 ! muscle organ [Term] id: GO:0007519 name: skeletal muscle tissue development namespace: biological_process alt_id: GO:0048637 def: "The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers." [GOC:mtg_muscle] synonym: "myogenesis" RELATED [] is_a: GO:0014706 ! striated muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001134 ! skeletal muscle tissue relationship: part_of GO:0060538 ! skeletal muscle organ development relationship: results_in_development_of UBERON:0001134 ! skeletal muscle tissue [Term] id: GO:0007525 name: somatic muscle development namespace: biological_process def: "The process whose specific outcome is the progression of the somatic muscle over time, from its formation to the mature structure. Somatic muscles are striated muscle structures that connect to the exoskeleton or cuticle." [GOC:jid, GOC:mtg_muscle] is_a: GO:0061061 ! muscle structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0014895 ! somatic muscle relationship: results_in_development_of UBERON:0014895 ! somatic muscle [Term] id: GO:0007528 name: neuromuscular junction development namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction." [GOC:mtg_OBO2OWL_2013] synonym: "neuromuscular junction organization" EXACT [] synonym: "neuromuscular junction stability" RELATED [GOC:pr] synonym: "NMJ stability" RELATED [GOC:pr] is_a: GO:0050808 ! synapse organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0031594 ! neuromuscular junction relationship: results_in_organization_of GO:0031594 ! neuromuscular junction [Term] id: GO:0007548 name: sex differentiation namespace: biological_process def: "The establishment of the sex of an organism by physical differentiation." [GOC:ai] xref: Wikipedia:Sexual_differentiation is_a: GO:0003006 ! developmental process involved in reproduction [Term] id: GO:0007565 name: female pregnancy namespace: biological_process def: "The set of physiological processes that allow an embryo or foetus to develop within the body of a female animal. It covers the time from fertilization of a female ovum by a male spermatozoon until birth." [ISBN:0192800825] subset: goslim_chembl synonym: "carrying of young" RELATED [] synonym: "gestation" EXACT [] xref: Wikipedia:Gestation is_a: GO:0044703 ! multi-organism reproductive process is_a: GO:0044706 ! multi-multicellular organism process relationship: in_taxon NCBITaxon:40674 {all_only="true"} ! Mammalia relationship: only_in_taxon NCBITaxon:40674 ! Mammalia [Term] id: GO:0007566 name: embryo implantation namespace: biological_process def: "Attachment of the blastocyst to the uterine lining." [GOC:isa_complete, http://www.medterms.com] synonym: "blastocyst implantation" EXACT [] is_a: GO:0022414 ! reproductive process relationship: part_of GO:0007275 ! multicellular organism development relationship: part_of GO:0007565 ! female pregnancy [Term] id: GO:0007585 name: respiratory gaseous exchange by respiratory system namespace: biological_process def: "The process of gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms." [ISBN:0198506732] subset: goslim_chembl synonym: "breathing" BROAD [] synonym: "respiration" BROAD [] is_a: GO:0032501 ! multicellular organismal process [Term] id: GO:0007586 name: digestion namespace: biological_process def: "The whole of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." [GOC:isa_complete, ISBN:0198506732] subset: goslim_chembl subset: goslim_pir xref: Wikipedia:Digestion is_a: GO:0032501 ! multicellular organismal process [Term] id: GO:0007588 name: excretion namespace: biological_process def: "The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds." [ISBN:0192801023] subset: gocheck_do_not_annotate subset: goslim_pir xref: Wikipedia:Excretion is_a: GO:0003008 ! system process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22368" xsd:anyURI [Term] id: GO:0007589 name: body fluid secretion namespace: biological_process def: "The controlled release of a fluid by a cell or tissue in an animal." [GOC:ai, GOC:dph, GOC:mah, GOC:tb] is_a: GO:0046903 ! secretion is_a: GO:0050878 ! regulation of body fluid levels [Term] id: GO:0007600 name: sensory perception namespace: biological_process def: "The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." [GOC:ai, GOC:dph] subset: goslim_drosophila xref: Wikipedia:Perception is_a: GO:0050877 ! nervous system process [Term] id: GO:0007601 name: visual perception namespace: biological_process def: "The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image." [GOC:ai] synonym: "sense of sight" EXACT [] synonym: "sensory visual perception" EXACT [] synonym: "vision" EXACT [] xref: Wikipedia:Visual_perception is_a: GO:0050953 ! sensory perception of light stimulus [Term] id: GO:0007605 name: sensory perception of sound namespace: biological_process def: "The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound." [GOC:ai] synonym: "hearing" EXACT [] synonym: "perception of sound" EXACT [] xref: Wikipedia:Hearing_(sense) is_a: GO:0050954 ! sensory perception of mechanical stimulus [Term] id: GO:0007606 name: sensory perception of chemical stimulus namespace: biological_process def: "The series of events required for an organism to receive a sensory chemical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." [GOC:ai] synonym: "chemosensory perception" EXACT [] is_a: GO:0007600 ! sensory perception [Term] id: GO:0007610 name: behavior namespace: biological_process alt_id: GO:0023032 alt_id: GO:0044708 alt_id: GO:0044709 def: "The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity." [GOC:ems, GOC:jl, ISBN:0395448956, PMID:20160973] comment: 1. Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation reviews.\n2. While a broader definition of behavior encompassing plants and single cell organisms would be justified on the basis of some usage (see PMID:20160973 for discussion), GO uses a tight definition that limits behavior to animals and to responses involving the nervous system, excluding plant responses that GO classifies under development, and responses of unicellular organisms that has general classifications for covering the responses of cells in multicellular organisms (e.g. cell chemotaxis). subset: gocheck_do_not_manually_annotate subset: goslim_agr subset: goslim_flybase_ribbon synonym: "behavioral response to stimulus" EXACT [] synonym: "behaviour" EXACT [] synonym: "behavioural response to stimulus" EXACT [] synonym: "single-organism behavior" RELATED [] xref: Wikipedia:Behavior is_a: GO:0032501 ! multicellular organismal process disjoint_from: GO:0032502 ! developmental process relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa relationship: process_has_causal_agent UBERON:0001016 ! nervous system created_by: jl creation_date: 2012-09-20T14:06:08Z [Term] id: GO:0007617 name: mating behavior namespace: biological_process def: "The behavioral interactions between organisms for the purpose of mating, or sexual reproduction resulting in the formation of zygotes." [GOC:ai, GOC:dph] synonym: "mating behaviour" EXACT [] xref: Wikipedia:Mating_behaviour is_a: GO:0019098 ! reproductive behavior [Term] id: GO:0007620 name: copulation namespace: biological_process def: "The act of sexual union between male and female, involving the transfer of sperm." [ISBN:0721662544] is_a: GO:0007617 ! mating behavior [Term] id: GO:0007626 name: locomotory behavior namespace: biological_process def: "The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions." [GOC:dph] subset: goslim_drosophila synonym: "behavior via locomotion" EXACT [] synonym: "locomotion in response to stimulus" EXACT [] synonym: "locomotory behavioral response to stimulus" EXACT [] synonym: "locomotory behaviour" EXACT [] synonym: "locomotory behavioural response to stimulus" EXACT [] is_a: GO:0007610 ! behavior [Term] id: GO:0008015 name: blood circulation namespace: biological_process alt_id: GO:0070261 def: "The flow of blood through the body of an animal, enabling the transport of nutrients to the tissues and the removal of waste products." [GOC:mtg_heart, ISBN:0192800825] subset: goslim_pir synonym: "hemolymph circulation" RELATED [] is_a: GO:0003013 ! circulatory system process [Term] id: GO:0008016 name: regulation of heart contraction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process in which the heart decreases in volume in a characteristic way to propel blood through the body." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "regulation of cardiac contraction" EXACT [] is_a: GO:1903522 ! regulation of blood circulation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060047 ! heart contraction relationship: regulates GO:0060047 ! heart contraction [Term] id: GO:0008028 name: monocarboxylic acid transmembrane transporter activity namespace: molecular_function alt_id: GO:0008505 def: "Enables the transfer of monocarboxylic acids from one side of a membrane to the other. A monocarboxylic acid is an organic acid with one COOH group." [GOC:ai] synonym: "monocarboxylate carrier" NARROW [] synonym: "prostaglandin/thromboxane transporter activity" NARROW [] xref: Reactome:R-HSA-429749 "SLC5A8 transports monocarboxylates from extracellular region to cytosol" xref: Reactome:R-HSA-433698 "SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol" xref: Reactome:R-HSA-5624211 "Defective SLC16A1 does not cotransport monocarboxylates, H+ from extracellular region to cytosol" xref: Reactome:R-HSA-9645220 "SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol" is_a: GO:0005342 ! organic acid transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:25384 ! monocarboxylic acid relationship: has_primary_input CHEBI:25384 ! monocarboxylic acid relationship: part_of GO:0015718 ! monocarboxylic acid transport [Term] id: GO:0008078 name: mesodermal cell migration namespace: biological_process def: "The orderly movement of mesodermal cells from one site to another." [GOC:ascb_2009, GOC:dph, GOC:mah, GOC:sat, GOC:tb, PMID:25119047] synonym: "mesoderm cell migration" EXACT [] is_a: GO:0001667 ! ameboidal-type cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000222 ! mesodermal cell relationship: results_in_movement_of CL:0000222 ! mesodermal cell [Term] id: GO:0008088 name: axo-dendritic transport namespace: biological_process def: "The directed movement of organelles or molecules along microtubules in neuron projections." [ISBN:0815316194] subset: goslim_synapse synonym: "axon cargo transport" NARROW [] synonym: "axonal transport" NARROW [] synonym: "axoplasmic transport" NARROW [] xref: Wikipedia:Axoplasmic_transport is_a: GO:0010970 ! transport along microtubule intersection_of: GO:0046907 ! intracellular transport intersection_of: occurs_in GO:0043005 ! neuron projection intersection_of: results_in_transport_along GO:0005874 ! microtubule relationship: occurs_in GO:0043005 ! neuron projection [Term] id: GO:0008104 name: protein localization namespace: biological_process alt_id: GO:0008105 alt_id: GO:0016249 alt_id: GO:0034613 def: "Any process in which a protein is transported to, or maintained in, a specific location." [GOC:ai] subset: goslim_drosophila synonym: "asymmetric protein localisation" RELATED [GOC:mah] synonym: "asymmetric protein localization" RELATED [] synonym: "cellular protein localisation" EXACT [GOC:mah] synonym: "cellular protein localization" EXACT [] synonym: "channel localizer activity" NARROW [GOC:mah] synonym: "establishment and maintenance of asymmetric protein localization" RELATED [] synonym: "establishment and maintenance of protein localization" RELATED [] synonym: "protein localisation" EXACT [GOC:mah] is_a: GO:0070727 ! cellular macromolecule localization intersection_of: GO:0051179 ! localization intersection_of: has_primary_input PR:000000001 ! protein relationship: has_primary_input PR:000000001 ! protein property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23112" xsd:anyURI [Term] id: GO:0008150 name: biological process name: biological_process namespace: biological_process alt_id: GO:0000004 alt_id: GO:0007582 alt_id: GO:0044699 def: "A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence." [GOC:pdt] def: "A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence." [GOC:pdt] comment: Note that, in addition to forming the root of the biological process ontology, this term is recommended for the annotation of gene products whose biological process is unknown. When this term is used for annotation, it indicates that no information was available about the biological process of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. comment: Note that, in addition to forming the root of the biological process ontology, this term is recommended for use for the annotation of gene products whose biological process is unknown. When this term is used for annotation, it indicates that no information was available about the biological process of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. subset: goslim_candida subset: goslim_chembl subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant subset: goslim_pombe subset: goslim_yeast synonym: "biological process" EXACT [] synonym: "physiological process" EXACT [] synonym: "single organism process" RELATED [] synonym: "single-organism process" RELATED [] xref: Wikipedia:Biological_process is_a: BFO:0000015 ! process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24968" xsd:anyURI created_by: jl creation_date: 2012-09-19T15:05:24Z [Term] id: GO:0008152 name: metabolic process namespace: biological_process alt_id: GO:0044236 alt_id: GO:0044710 def: "The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation." [GOC:go_curators, ISBN:0198547684] comment: Note that metabolic processes do not include single functions or processes such as protein-protein interactions, protein-nucleic acids, nor receptor-ligand interactions. subset: gocheck_do_not_manually_annotate subset: goslim_chembl subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant synonym: "metabolic process resulting in cell growth" NARROW [] synonym: "metabolism" EXACT [] synonym: "metabolism resulting in cell growth" NARROW [] synonym: "multicellular organism metabolic process" NARROW [] synonym: "single-organism metabolic process" RELATED [] xref: Wikipedia:Metabolism is_a: GO:0008150 ! biological process disjoint_from: GO:0051179 ! localization created_by: jl creation_date: 2012-10-17T15:46:40Z [Term] id: GO:0008202 name: steroid metabolic process namespace: biological_process def: "The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus." [ISBN:0198547684] synonym: "steroid metabolism" EXACT [] xref: Wikipedia:Steroid_metabolism is_a: GO:0006629 ! lipid metabolic process is_a: GO:1901360 ! organic cyclic compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:35341 ! steroid relationship: has_primary_input_or_output CHEBI:35341 ! steroid [Term] id: GO:0008206 name: bile acid metabolic process namespace: biological_process def: "The chemical reactions and pathways involving bile acids, a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine." [GOC:go_curators] synonym: "bile acid metabolism" EXACT [] is_a: GO:0008202 ! steroid metabolic process is_a: GO:0032787 ! monocarboxylic acid metabolic process is_a: GO:1901615 ! organic hydroxy compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:36235 ! bile acid anion relationship: has_primary_input_or_output CHEBI:36235 ! bile acid anion [Term] id: GO:0008219 name: cell death namespace: biological_process def: "Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538)." [GOC:mah, GOC:mtg_apoptosis, PMID:25236395] comment: This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms. subset: gocheck_do_not_annotate synonym: "accidental cell death" RELATED [] synonym: "necrosis" RELATED [] is_a: GO:0009987 ! cellular process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24680" xsd:anyURI [Term] id: GO:0008272 name: sulfate transport namespace: biological_process alt_id: GO:0006870 def: "The directed movement of sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] synonym: "sulphate transport" EXACT [] is_a: GO:0015698 ! inorganic anion transport is_a: GO:0072348 ! sulfur compound transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:16189 ! sulfate relationship: has_primary_input CHEBI:16189 ! sulfate [Term] id: GO:0008283 name: cell population proliferation namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population." [GOC:mah, GOC:mb] comment: This term was moved out from being a child of 'cellular process' because it is a cell population-level process, and cellular processes are restricted to those processes that involve individual cells. Also note that this term is intended to be used for the proliferation of cells within a multicellular organism, not for the expansion of a population of single-celled organisms. subset: goslim_agr subset: goslim_chembl subset: goslim_drosophila subset: goslim_flybase_ribbon subset: goslim_mouse subset: goslim_pir synonym: "cell proliferation" RELATED [] is_a: GO:0009987 ! cellular process property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0008284 name: positive regulation of cell population proliferation namespace: biological_process def: "Any process that activates or increases the rate or extent of cell proliferation." [GOC:go_curators] synonym: "activation of cell proliferation" NARROW [] synonym: "positive regulation of cell proliferation" RELATED [] synonym: "stimulation of cell proliferation" NARROW [] synonym: "up regulation of cell proliferation" EXACT [] synonym: "up-regulation of cell proliferation" EXACT [] synonym: "upregulation of cell proliferation" EXACT [] is_a: GO:0042127 ! regulation of cell population proliferation is_a: GO:0048522 ! positive regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0008283 ! cell population proliferation relationship: positively_regulates GO:0008283 ! cell population proliferation property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0008285 name: negative regulation of cell population proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of cell proliferation." [GOC:go_curators] synonym: "down regulation of cell proliferation" EXACT [] synonym: "down-regulation of cell proliferation" EXACT [] synonym: "downregulation of cell proliferation" EXACT [] synonym: "inhibition of cell proliferation" NARROW [] synonym: "negative regulation of cell proliferation" RELATED [] is_a: GO:0042127 ! regulation of cell population proliferation is_a: GO:0048523 ! negative regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0008283 ! cell population proliferation relationship: negatively_regulates GO:0008283 ! cell population proliferation property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0008291 name: acetylcholine metabolic process namespace: biological_process def: "The chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." [GOC:jl, GOC:nln, ISBN:0192800752] synonym: "acetylcholine metabolism" EXACT [] is_a: GO:0006807 ! nitrogen compound metabolic process is_a: GO:1900619 ! acetate ester metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:15355 ! acetylcholine relationship: has_primary_input_or_output CHEBI:15355 ! acetylcholine [Term] id: GO:0008292 name: acetylcholine biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of acetylcholine, the acetic acid ester of the organic base choline." [GOC:jl, ISBN:0192800752] synonym: "acetylcholine anabolism" EXACT [] synonym: "acetylcholine biosynthesis" EXACT [] synonym: "acetylcholine formation" EXACT [] synonym: "acetylcholine synthesis" EXACT [] is_a: GO:0008291 ! acetylcholine metabolic process is_a: GO:1900620 ! acetate ester biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:15355 ! acetylcholine relationship: has_primary_output CHEBI:15355 ! acetylcholine [Term] id: GO:0008320 name: protein transmembrane transporter activity namespace: molecular_function alt_id: GO:0015266 alt_id: GO:0015463 def: "Enables the transfer of a protein from one side of a membrane to the other." [GOC:jl] synonym: "protein channel activity" RELATED [] xref: Reactome:R-HSA-1268022 "TOMM40 complex translocates proteins from the cytosol to the mitochondrial intermembrane space" xref: Reactome:R-HSA-1299475 "TIMM23 PAM translocates proteins from the mitochondrial intermembrane space to the mitochondrial matrix" xref: Reactome:R-HSA-184269 "Monoubiquitinated N-myristoyl GAG polyprotein is targeted to the late endosomal vesicle membrane by the ESCRT-I complex" xref: Reactome:R-HSA-3149434 "Transport of GAG to the Plasma Membrane" xref: Reactome:R-HSA-5205661 "Pink1 is recruited from the cytoplasm to the mitochondria" xref: Reactome:R-HSA-5210943 "pagA(197-794):ANTRX2 oligomer transports cya and lef (target cell endosome to cytosol)" xref: Reactome:R-HSA-5210947 "pagA(197-794):ANTRX1 oligomer transports cya and lef (target cell endosome to cytosol)" xref: Reactome:R-HSA-5228406 "tetX HC transports tetX LC from target cell endosome membrane into cytosol" xref: Reactome:R-HSA-5229111 "AP4 transports APP from trans-Golgi network to endosome lumen" xref: Reactome:R-HSA-5244404 "botB HC transports botB LC from target cell synaptic vesicle membrane into cytosol" xref: Reactome:R-HSA-5244428 "botA HC transports botA LC from target cell synaptic vesicle membrane into cytosol" xref: Reactome:R-HSA-5244506 "botE HC transports botE LC from target cell synaptic vesicle membrane into cytosol" xref: Reactome:R-HSA-5246514 "botC HC transports botC LC from target cell synaptic vesicle membrane to cytosol" xref: Reactome:R-HSA-5250616 "botD HC transports botD LC from target cell synaptic vesicle membrane into cytosol" xref: Reactome:R-HSA-5250884 "botF HC transports botF LC from target cell synaptic vesicle membrane into cytosol" xref: Reactome:R-HSA-5250972 "botG HC transports botG LC from target cell synaptic vesicle membrane into cytosol" xref: Reactome:R-HSA-5336420 "DT fragment B transports DT fragment A from target cell endosome membrane" xref: Reactome:R-HSA-9636375 "SecA2 transports SapM from cytoplasm to cytosol" xref: Reactome:R-HSA-9698930 "HCMV C Nucleocapsid Translocation" xref: Reactome:R-HSA-9698933 "HCMV B Nucleocapsid Translocation" is_a: GO:0022857 ! transmembrane transporter activity is_a: GO:0140318 ! protein transporter activity intersection_of: GO:0005215 ! transporter activity intersection_of: has_primary_input PR:000000001 ! protein intersection_of: results_in_transport_across GO:0016020 ! membrane relationship: part_of GO:0071806 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! protein transmembrane transport [Term] id: GO:0008324 name: monoatomic cation transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of cation from one side of a membrane to the other." [GOC:dgf, GOC:mtg_transport, ISBN:0815340729] synonym: "cation transmembrane transporter activity" BROAD [] synonym: "transmembrane cation transporter activity" EXACT [] is_a: GO:0015075 ! monoatomic ion transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:23906 ! monoatomic cation relationship: has_primary_input CHEBI:23906 ! monoatomic cation relationship: part_of GO:0098655 ! monoatomic cation transmembrane transport property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24479" xsd:anyURI [Term] id: GO:0008347 name: glial cell migration namespace: biological_process alt_id: GO:0043359 def: "The orderly movement of a glial cell, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system." [GOC:jl, GOC:mtg_sensu] synonym: "glia cell migration" EXACT [] is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000125 ! glial cell relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0042063 ! gliogenesis relationship: results_in_movement_of CL:0000125 ! glial cell [Term] id: GO:0008354 name: germ cell migration namespace: biological_process def: "The orderly movement of a cell specialized to produce haploid gametes through the embryo from its site of production to the place where the gonads will form." [GOC:bf, GOC:jl] synonym: "germ-cell migration" EXACT [] synonym: "primordial germ cell migration" RELATED [] is_a: GO:0016477 ! cell migration is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000586 ! germ cell relationship: part_of GO:0007276 ! gamete generation relationship: results_in_movement_of CL:0000586 ! germ cell [Term] id: GO:0008356 name: asymmetric cell division namespace: biological_process def: "The asymmetric division of cells to produce two daughter cells with different developmental potentials. It is of fundamental significance for the generation of cell diversity." [PMID:11672519] synonym: "asymmetric cytokinesis" RELATED [] synonym: "asymmetrical cell division" EXACT [] synonym: "asymmetrical cytokinesis" RELATED [] xref: Wikipedia:Asymmetric_cell_division is_a: GO:0051301 ! cell division [Term] id: GO:0008358 name: maternal determination of anterior/posterior axis, embryo namespace: biological_process def: "The specification of the anterior/posterior axis of the embryo by gradients of maternally-transcribed gene products; exemplified in insects by the morphogens, bicoid and nanos." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238] is_a: GO:0008595 ! anterior/posterior axis specification, embryo [Term] id: GO:0008406 name: gonad development namespace: biological_process def: "The process whose specific outcome is the progression of the gonad over time, from its formation to the mature structure. The gonad is an animal organ that produces gametes; in some species it also produces hormones." [GOC:ems, ISBN:0198506732] synonym: "gonadogenesis" EXACT [GOC:cjm] is_a: GO:0048513 ! animal organ development is_a: GO:0048608 ! reproductive structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000991 ! gonad relationship: part_of GO:0045137 ! development of primary sexual characteristics relationship: results_in_development_of UBERON:0000991 ! gonad [Term] id: GO:0008504 name: monoamine transmembrane transporter activity namespace: molecular_function alt_id: GO:0015201 def: "Enables the transfer of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), from one side of a membrane to the other." [GOC:mah] xref: Reactome:R-HSA-372542 "Loading of dopamine into synaptic veiscles" xref: Reactome:R-HSA-379393 "SLC6A3 cotransports DA, Na+ from extracellular region to cytosol" xref: Reactome:R-HSA-380586 "loading of Serotonin in synaptic vesicles" xref: Reactome:R-HSA-380620 "Reuptake of serotonin from the synapse" xref: Reactome:R-HSA-444160 "VMAT1/2 can mediate the transport of biogenic amines" xref: Reactome:R-HSA-5660706 "Defective SLC6A3 does not cotransport DA, Na+ from extracellular region to cytosol" is_a: GO:0022804 ! active transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:63534 ! monoamine relationship: has_primary_input CHEBI:63534 ! monoamine relationship: part_of GO:0015844 ! monoamine transport [Term] id: GO:0008514 name: organic anion transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of organic anions from one side of a membrane to the other. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage." [GOC:ai] xref: Reactome:R-HSA-2142859 "Growing HA is extruded from the cell by ABCC5" xref: Reactome:R-HSA-561041 "OAT1-3 transport organic anions with antiport of dicarboxylic acids" xref: Reactome:R-HSA-9794830 "SLC22A8 transports Cipro into renal cell" is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:25696 ! organic anion relationship: has_primary_input CHEBI:25696 ! organic anion relationship: part_of GO:0015711 ! organic anion transport [Term] id: GO:0008544 name: epidermis development namespace: biological_process def: "The process whose specific outcome is the progression of the epidermis over time, from its formation to the mature structure. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species." [GOC:go_curators, UBERON:0001003] synonym: "hypodermis development" RELATED [GOC:kmv, GOC:rk] is_a: GO:0009888 ! tissue development property_value: RO:0002161 NCBITaxon:33090 [Term] id: GO:0008584 name: male gonad development namespace: biological_process def: "The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure." [GOC:jid] synonym: "testicular development" EXACT [GOC:sl] synonym: "testis development" EXACT [GOC:sl] is_a: GO:0008406 ! gonad development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000473 ! testis relationship: part_of GO:0046546 ! development of primary male sexual characteristics relationship: results_in_development_of UBERON:0000473 ! testis [Term] id: GO:0008585 name: female gonad development namespace: biological_process alt_id: GO:0061039 def: "The process whose specific outcome is the progression of the female gonad over time, from its formation to the mature structure." [GOC:dph, GOC:jid, GOC:tb] synonym: "ovarian development" RELATED [GOC:sl] synonym: "ovary development" RELATED [GOC:sl] is_a: GO:0008406 ! gonad development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000992 ! ovary relationship: part_of GO:0046545 ! development of primary female sexual characteristics relationship: results_in_development_of UBERON:0000992 ! ovary property_value: RO:0002161 NCBITaxon:3398 [Term] id: GO:0008594 name: photoreceptor cell morphogenesis namespace: biological_process def: "The process in which the structures of a photoreceptor cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a photoreceptor cell, a sensory cell that reacts to the presence of light. An example of this is found in Drosophila melanogaster." [GOC:jid, GOC:mah] synonym: "photoreceptor development" RELATED [] is_a: GO:0048667 ! cell morphogenesis involved in neuron differentiation intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of CL:0000210 ! photoreceptor cell relationship: part_of GO:0042461 ! photoreceptor cell development relationship: results_in_morphogenesis_of CL:0000210 ! photoreceptor cell [Term] id: GO:0008595 name: anterior/posterior axis specification, embryo namespace: biological_process def: "The specification of the anterior/posterior axis of the embryo by the products of genes expressed maternally and genes expressed in the zygote." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238] synonym: "anterior/posterior axis determination, embryo" RELATED [GOC:dph] is_a: GO:0000578 ! embryonic axis specification is_a: GO:0009948 ! anterior/posterior axis specification relationship: part_of GO:0007351 ! tripartite regional subdivision [Term] id: GO:0008610 name: lipid biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent." [GOC:go_curators] synonym: "lipid anabolism" EXACT [] synonym: "lipid biosynthesis" EXACT [] synonym: "lipid formation" EXACT [] synonym: "lipid synthesis" EXACT [] synonym: "lipogenesis" EXACT [GOC:sl] is_a: GO:0006629 ! lipid metabolic process is_a: GO:1901576 ! organic substance biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:18059 ! lipid relationship: has_primary_output CHEBI:18059 ! lipid [Term] id: GO:0008643 name: carbohydrate transport namespace: biological_process alt_id: GO:0006861 alt_id: GO:0008644 def: "The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are a group of organic compounds based of the general formula Cx(H2O)y." [GOC:ai] subset: goslim_pir subset: goslim_yeast synonym: "sugar transport" NARROW [] is_a: GO:0071702 ! organic substance transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:16646 ! carbohydrate relationship: has_primary_input CHEBI:16646 ! carbohydrate [Term] id: GO:0008645 name: hexose transmembrane transport namespace: biological_process alt_id: GO:0008646 alt_id: GO:0008647 alt_id: GO:0035428 def: "The process in which hexose is transported across a membrane. Hexoses are aldoses with a chain of six carbon atoms in the molecule." [GOC:vw] comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "hexose membrane transport" RELATED [] synonym: "hexose transport" RELATED [] synonym: "high-affinity hexose transport" NARROW [] synonym: "low-affinity hexose transport" NARROW [] is_a: GO:0015749 ! monosaccharide transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:18133 ! hexose intersection_of: results_in_transport_across GO:0016020 ! membrane relationship: has_primary_input CHEBI:18133 ! hexose created_by: bf creation_date: 2010-04-08T10:27:23Z [Term] id: GO:0008652 name: amino acid biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents." [ISBN:0198506732] synonym: "amino acid anabolism" EXACT [] synonym: "amino acid biosynthesis" EXACT [] synonym: "amino acid formation" EXACT [] synonym: "amino acid synthesis" EXACT [] synonym: "cellular amino acid biosynthetic process" EXACT [] xref: Wikipedia:Amino_acid_synthesis is_a: GO:0046394 ! carboxylic acid biosynthetic process is_a: GO:1901566 ! organonitrogen compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:37022 ! amino-acid anion relationship: has_primary_output CHEBI:37022 ! amino-acid anion property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/17904" xsd:anyURI [Term] id: GO:0009056 name: catabolic process namespace: biological_process alt_id: GO:0044243 alt_id: GO:0044712 def: "The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism." [ISBN:0198547684] subset: goslim_agr subset: goslim_chembl subset: goslim_plant synonym: "breakdown" EXACT [] synonym: "catabolism" EXACT [] synonym: "degradation" EXACT [] synonym: "multicellular organismal catabolic process" NARROW [] synonym: "single-organism catabolic process" RELATED [] xref: Wikipedia:Catabolism is_a: GO:0008152 ! metabolic process created_by: jl creation_date: 2012-10-17T15:52:35Z [Term] id: GO:0009057 name: macromolecule catabolic process namespace: biological_process alt_id: GO:0043285 alt_id: GO:0044266 def: "The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:mah] subset: goslim_pir synonym: "biopolymer catabolic process" EXACT [GOC:mtg_chebi_dec09] synonym: "cellular macromolecule catabolic process" RELATED [] synonym: "cellular macromolecule catabolism" RELATED [] synonym: "cellular macromolecule degradation" RELATED [] synonym: "macromolecule breakdown" EXACT [] synonym: "macromolecule catabolism" EXACT [] synonym: "macromolecule degradation" EXACT [] synonym: "multicellular organismal macromolecule catabolic process" NARROW [] is_a: GO:0043170 ! macromolecule metabolic process is_a: GO:1901575 ! organic substance catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:33694 ! biomacromolecule relationship: has_primary_input CHEBI:33694 ! biomacromolecule [Term] id: GO:0009058 name: biosynthetic process namespace: biological_process alt_id: GO:0044274 alt_id: GO:0044711 def: "The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones." [GOC:curators, ISBN:0198547684] subset: goslim_chembl subset: goslim_metagenomics subset: goslim_plant synonym: "anabolism" EXACT [] synonym: "biosynthesis" EXACT [] synonym: "formation" BROAD [] synonym: "multicellular organismal biosynthetic process" NARROW [] synonym: "single-organism biosynthetic process" RELATED [] synonym: "synthesis" EXACT [] xref: Wikipedia:Anabolism is_a: GO:0008152 ! metabolic process created_by: jl creation_date: 2012-10-17T15:52:18Z [Term] id: GO:0009059 name: macromolecule biosynthetic process namespace: biological_process alt_id: GO:0043284 def: "The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:mah] subset: goslim_pir synonym: "biopolymer biosynthetic process" EXACT [GOC:mtg_chebi_dec09] synonym: "macromolecule anabolism" EXACT [] synonym: "macromolecule biosynthesis" EXACT [] synonym: "macromolecule formation" EXACT [] synonym: "macromolecule synthesis" EXACT [] is_a: GO:0043170 ! macromolecule metabolic process is_a: GO:0044249 ! cellular biosynthetic process is_a: GO:1901576 ! organic substance biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:33694 ! biomacromolecule relationship: has_primary_output CHEBI:33694 ! biomacromolecule property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/15249" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/25418" xsd:anyURI [Term] id: GO:0009063 name: amino acid catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents." [GOC:ai] synonym: "amino acid breakdown" EXACT [] synonym: "amino acid catabolism" EXACT [] synonym: "amino acid degradation" EXACT [] synonym: "cellular amino acid catabolic process" EXACT [] is_a: GO:0046395 ! carboxylic acid catabolic process is_a: GO:1901565 ! organonitrogen compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:37022 ! amino-acid anion relationship: has_primary_input CHEBI:37022 ! amino-acid anion property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/17904" xsd:anyURI [Term] id: GO:0009100 name: glycoprotein metabolic process namespace: biological_process def: "The chemical reactions and pathways involving glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:go_curators, ISBN:0198506732] subset: goslim_drosophila synonym: "glycoprotein metabolism" EXACT [] is_a: GO:0043170 ! macromolecule metabolic process is_a: GO:1901135 ! carbohydrate derivative metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:17089 ! glycoprotein relationship: has_primary_input_or_output CHEBI:17089 ! glycoprotein [Term] id: GO:0009101 name: glycoprotein biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:go_curators, ISBN:0198506732] synonym: "glycoprotein anabolism" EXACT [] synonym: "glycoprotein biosynthesis" EXACT [] synonym: "glycoprotein formation" EXACT [] synonym: "glycoprotein synthesis" EXACT [] is_a: GO:0009059 ! macromolecule biosynthetic process is_a: GO:0009100 ! glycoprotein metabolic process is_a: GO:1901137 ! carbohydrate derivative biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:17089 ! glycoprotein relationship: has_primary_output CHEBI:17089 ! glycoprotein [Term] id: GO:0009112 name: nucleobase metabolic process namespace: biological_process def: "The chemical reactions and pathways involving a nucleobase, a nitrogenous base that is a constituent of a nucleic acid, e.g. the purines: adenine, guanine, hypoxanthine, xanthine and the pyrimidines: cytosine, uracil, thymine." [GOC:ma] synonym: "nucleobase metabolism" EXACT [] is_a: GO:0055086 ! nucleobase-containing small molecule metabolic process is_a: GO:1901564 ! organonitrogen compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:18282 ! nucleobase relationship: has_primary_input_or_output CHEBI:18282 ! nucleobase [Term] id: GO:0009250 name: glucan biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues." [GOC:go_curators] synonym: "glucan anabolism" EXACT [] synonym: "glucan biosynthesis" EXACT [] synonym: "glucan formation" EXACT [] synonym: "glucan synthesis" EXACT [] is_a: GO:0000271 ! polysaccharide biosynthetic process is_a: GO:0044042 ! glucan metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:37163 ! glucan relationship: has_primary_output CHEBI:37163 ! glucan [Term] id: GO:0009251 name: glucan catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of glucans, polysaccharides consisting only of glucose residues." [GOC:go_curators] synonym: "glucan breakdown" EXACT [] synonym: "glucan catabolism" EXACT [] synonym: "glucan degradation" EXACT [] is_a: GO:0000272 ! polysaccharide catabolic process is_a: GO:0044042 ! glucan metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:37163 ! glucan relationship: has_primary_input CHEBI:37163 ! glucan [Term] id: GO:0009306 name: protein secretion namespace: biological_process alt_id: GO:0045166 alt_id: GO:0045731 def: "The controlled release of proteins from a cell." [GOC:ai] synonym: "glycoprotein secretion" NARROW [] synonym: "protein secretion during cell fate commitment" NARROW [] synonym: "protein secretion resulting in cell fate commitment" NARROW [] is_a: GO:0015031 ! protein transport is_a: GO:0032940 ! secretion by cell is_a: GO:0035592 ! establishment of protein localization to extracellular region is_a: GO:0071692 ! protein localization to extracellular region intersection_of: GO:0046903 ! secretion intersection_of: has_primary_input PR:000000001 ! protein [Term] id: GO:0009308 name: amine metabolic process namespace: biological_process alt_id: GO:0044106 def: "The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom." [GOC:jl, ISBN:0198506732] subset: goslim_chembl subset: goslim_pir synonym: "amine metabolism" EXACT [] synonym: "cellular amine metabolic process" EXACT [] is_a: GO:1901564 ! organonitrogen compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:32952 ! amine relationship: has_primary_input_or_output CHEBI:32952 ! amine created_by: jl creation_date: 2009-07-15T11:55:44Z [Term] id: GO:0009309 name: amine biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom." [GOC:jl, ISBN:0198506732] synonym: "amine anabolism" EXACT [] synonym: "amine biosynthesis" EXACT [] synonym: "amine formation" EXACT [] synonym: "amine synthesis" EXACT [] is_a: GO:0009308 ! amine metabolic process is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process is_a: GO:1901566 ! organonitrogen compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:32952 ! amine relationship: has_primary_output CHEBI:32952 ! amine [Term] id: GO:0009310 name: amine catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom." [GOC:jl, ISBN:0198506732] synonym: "amine breakdown" EXACT [] synonym: "amine catabolism" EXACT [] synonym: "amine degradation" EXACT [] is_a: GO:0009308 ! amine metabolic process is_a: GO:1901565 ! organonitrogen compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:32952 ! amine relationship: has_primary_input CHEBI:32952 ! amine [Term] id: GO:0009314 name: response to radiation namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation." [GOC:jl, Wikipedia:Electromagnetic_radiation] comment: Note that 'radiation' refers to electromagnetic radiation of any wavelength. synonym: "response to electromagnetic radiation stimulus" EXACT [] synonym: "response to radiation stimulus" EXACT [] is_a: GO:0009628 ! response to abiotic stimulus [Term] id: GO:0009416 name: response to light stimulus namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light." [GOC:go_curators, ISBN:0582227089] subset: goslim_plant is_a: GO:0009314 ! response to radiation intersection_of: GO:0050896 ! response to stimulus intersection_of: has_primary_input CHEBI:30212 ! photon relationship: has_primary_input CHEBI:30212 ! photon [Term] id: GO:0009566 name: fertilization namespace: biological_process def: "The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy)." [GOC:tb, ISBN:0198506732] synonym: "syngamy" EXACT [] xref: Wikipedia:Fertilisation is_a: GO:0022414 ! reproductive process intersection_of: GO:0022414 ! reproductive process intersection_of: results_in_formation_of_anatomical_entity CL:0010017 ! zygote intersection_of: results_in_fusion_of GO:0043073 ! germ cell nucleus relationship: part_of GO:0019953 ! sexual reproduction relationship: results_in_formation_of_anatomical_entity CL:0010017 ! zygote relationship: results_in_fusion_of GO:0043073 ! germ cell nucleus property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/20176" xsd:anyURI [Term] id: GO:0009581 name: detection of external stimulus namespace: biological_process def: "The series of events in which an external stimulus is received by a cell and converted into a molecular signal." [GOC:hb] synonym: "perception of external stimulus" RELATED [] is_a: GO:0009605 ! response to external stimulus is_a: GO:0051606 ! detection of stimulus [Term] id: GO:0009582 name: detection of abiotic stimulus namespace: biological_process def: "The series of events in which an (non-living) abiotic stimulus is received by a cell and converted into a molecular signal." [GOC:hb] synonym: "perception of abiotic stimulus" RELATED [] is_a: GO:0009628 ! response to abiotic stimulus is_a: GO:0051606 ! detection of stimulus [Term] id: GO:0009583 name: detection of light stimulus namespace: biological_process def: "The series of events in which a light stimulus (in the form of photons) is received and converted into a molecular signal." [GOC:go_curators] synonym: "detection of light" EXACT [] synonym: "perception of light" RELATED [] is_a: GO:0009416 ! response to light stimulus is_a: GO:0009581 ! detection of external stimulus is_a: GO:0009582 ! detection of abiotic stimulus [Term] id: GO:0009584 name: detection of visible light namespace: biological_process def: "The series of events in which a visible light stimulus is received by a cell and converted into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm." [GOC:go_curators, ISBN:0198506732] synonym: "perception of visible light" RELATED [] is_a: GO:0009583 ! detection of light stimulus [Term] id: GO:0009593 name: detection of chemical stimulus namespace: biological_process def: "The series of events in which a chemical stimulus is received by a cell and converted into a molecular signal." [GOC:jl] synonym: "chemoperception" EXACT [] synonym: "chemoreception" RELATED [] synonym: "detection of chemical substance" EXACT [] synonym: "perception of chemical stimulus" RELATED [] synonym: "perception of chemical substance" RELATED [] is_a: GO:0051606 ! detection of stimulus relationship: part_of GO:0042221 ! response to chemical [Term] id: GO:0009605 name: response to external stimulus namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus." [GOC:hb] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_manually_annotate subset: goslim_drosophila subset: goslim_plant synonym: "response to environmental stimulus" EXACT [] is_a: GO:0050896 ! response to stimulus [Term] id: GO:0009607 name: response to biotic stimulus namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism." [GOC:hb] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_manually_annotate subset: goslim_metagenomics subset: goslim_plant synonym: "response to biotic stress" NARROW [] is_a: GO:0050896 ! response to stimulus [Term] id: GO:0009617 name: response to bacterium namespace: biological_process alt_id: GO:0009618 alt_id: GO:0009680 def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium." [GOC:hb] synonym: "response to bacteria" EXACT [] is_a: GO:0051707 ! response to other organism intersection_of: GO:0050896 ! response to stimulus intersection_of: has_primary_input NCBITaxon:2 ! Bacteria relationship: has_primary_input NCBITaxon:2 ! Bacteria [Term] id: GO:0009620 name: response to fungus namespace: biological_process alt_id: GO:0009621 def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a fungus." [GOC:hb] synonym: "response to fungi" EXACT [] is_a: GO:0051707 ! response to other organism intersection_of: GO:0050896 ! response to stimulus intersection_of: has_primary_input NCBITaxon:4751 ! Fungi relationship: has_primary_input NCBITaxon:4751 ! Fungi [Term] id: GO:0009628 name: response to abiotic stimulus namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (not derived from living organisms) stimulus." [GOC:hb] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_manually_annotate subset: goslim_metagenomics subset: goslim_plant synonym: "response to abiotic stress" NARROW [] is_a: GO:0050896 ! response to stimulus property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/16572" xsd:anyURI [Term] id: GO:0009636 name: response to toxic substance namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus." [GOC:lr] subset: goslim_chembl synonym: "detoxification response" NARROW [] synonym: "toxin resistance" RELATED [] synonym: "toxin susceptibility/resistance" RELATED [] is_a: GO:0042221 ! response to chemical [Term] id: GO:0009653 name: anatomical structure morphogenesis namespace: biological_process def: "The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form." [GOC:go_curators, ISBN:0521436125] synonym: "anatomical structure organization" EXACT [] synonym: "embryogenesis and morphogenesis" BROAD [] synonym: "morphogenesis" EXACT [] xref: Wikipedia:Morphogenesis is_a: GO:0032502 ! developmental process disjoint_from: GO:0048856 ! anatomical structure development disjoint_from: GO:0071695 ! anatomical structure maturation relationship: part_of GO:0048856 ! anatomical structure development [Term] id: GO:0009712 name: catechol-containing compound metabolic process namespace: biological_process def: "The chemical reactions and pathways involving a compound containing a pyrocatechol (1,2-benzenediol) nucleus or substituent." [GOC:sm, ISBN:0198547684] synonym: "catechol metabolic process" RELATED [] synonym: "catechol metabolism" RELATED [] is_a: GO:0018958 ! phenol-containing compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:33566 ! catechols relationship: has_primary_input_or_output CHEBI:33566 ! catechols [Term] id: GO:0009713 name: catechol-containing compound biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent." [GOC:go_curators] synonym: "catechol anabolism" RELATED [] synonym: "catechol biosynthesis" RELATED [] synonym: "catechol biosynthetic process" RELATED [] synonym: "catechol formation" RELATED [] synonym: "catechol synthesis" RELATED [] is_a: GO:0009712 ! catechol-containing compound metabolic process is_a: GO:0046189 ! phenol-containing compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:33566 ! catechols relationship: has_primary_output CHEBI:33566 ! catechols [Term] id: GO:0009719 name: response to endogenous stimulus namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism." [GOC:sm] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_manually_annotate subset: goslim_plant is_a: GO:0050896 ! response to stimulus [Term] id: GO:0009725 name: response to hormone namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus." [GOC:jl] synonym: "growth regulator" RELATED [] synonym: "response to hormone stimulus" EXACT [GOC:dos] is_a: GO:0009719 ! response to endogenous stimulus is_a: GO:0010033 ! response to organic substance [Term] id: GO:0009743 name: response to carbohydrate namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus." [GOC:jl] synonym: "response to carbohydrate stimulus" EXACT [GOC:dos] is_a: GO:0010033 ! response to organic substance is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus intersection_of: has_primary_input CHEBI:16646 ! carbohydrate relationship: has_primary_input CHEBI:16646 ! carbohydrate [Term] id: GO:0009746 name: response to hexose namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus." [GOC:jl] synonym: "response to hexose stimulus" EXACT [GOC:dos] is_a: GO:0034284 ! response to monosaccharide intersection_of: GO:0050896 ! response to stimulus intersection_of: has_primary_input CHEBI:18133 ! hexose relationship: has_primary_input CHEBI:18133 ! hexose [Term] id: GO:0009749 name: response to glucose namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus." [GOC:jl] synonym: "response to glucose stimulus" EXACT [GOC:dos] is_a: GO:0009746 ! response to hexose intersection_of: GO:0050896 ! response to stimulus intersection_of: has_primary_input CHEBI:17234 ! glucose relationship: has_primary_input CHEBI:17234 ! glucose [Term] id: GO:0009786 name: regulation of asymmetric cell division namespace: biological_process def: "Any process that modulates the frequency, rate or extent of asymmetric cell division." [GOC:lr] is_a: GO:0051302 ! regulation of cell division intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0008356 ! asymmetric cell division relationship: regulates GO:0008356 ! asymmetric cell division [Term] id: GO:0009790 name: embryo development namespace: biological_process alt_id: GO:0009795 def: "The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant." [GOC:go_curators, GOC:isa_complete, GOC:mtg_sensu] subset: gocheck_do_not_manually_annotate subset: goslim_chembl subset: goslim_plant synonym: "embryogenesis" EXACT [] synonym: "embryogenesis and morphogenesis" BROAD [] synonym: "embryonal development" EXACT [] xref: Wikipedia:Embryogenesis is_a: GO:0007275 ! multicellular organism development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000922 ! embryo relationship: results_in_development_of UBERON:0000922 ! embryo [Term] id: GO:0009791 name: post-embryonic development namespace: biological_process def: "The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development." [GOC:go_curators] subset: goslim_plant is_a: GO:0032501 ! multicellular organismal process relationship: part_of GO:0007275 ! multicellular organism development [Term] id: GO:0009792 name: embryo development ending in birth or egg hatching namespace: biological_process def: "The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell." [GOC:go_curators, GOC:isa_complete, GOC:mtg_sensu] synonym: "embryogenesis" BROAD [] is_a: GO:0009790 ! embryo development relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa [Term] id: GO:0009798 name: axis specification namespace: biological_process def: "The establishment, maintenance and elaboration of a pattern along a line or around a point." [GOC:dph, GOC:go_curators, GOC:isa_complete] synonym: "axis determination" RELATED [] is_a: GO:0007389 ! pattern specification process [Term] id: GO:0009820 name: alkaloid metabolic process namespace: biological_process def: "The chemical reactions and pathways involving alkaloids, nitrogen containing natural products which are not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases)." [GOC:lr, ISBN:0122146743] subset: goslim_chembl synonym: "alkaloid metabolism" EXACT [] is_a: GO:1901564 ! organonitrogen compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:22315 ! alkaloid relationship: has_primary_input_or_output CHEBI:22315 ! alkaloid [Term] id: GO:0009821 name: alkaloid biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of alkaloids, nitrogen-containing natural products which are not otherwise classified as nonprotein amino acids, amines, peptides, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones, or primary metabolite (such as purine or pyrimidine bases)." [GOC:lr, ISBN:0122146743] synonym: "alkaloid anabolism" EXACT [] synonym: "alkaloid biosynthesis" EXACT [] synonym: "alkaloid formation" EXACT [] synonym: "alkaloid synthesis" EXACT [] xref: UM-BBD_enzymeID:e0711 is_a: GO:0009820 ! alkaloid metabolic process is_a: GO:0044550 ! secondary metabolite biosynthetic process is_a: GO:1901566 ! organonitrogen compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:22315 ! alkaloid relationship: has_primary_output CHEBI:22315 ! alkaloid [Term] id: GO:0009822 name: alkaloid catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of alkaloids, nitrogen containing natural products not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases)." [GOC:lr, ISBN:0122146743] synonym: "alkaloid breakdown" EXACT [] synonym: "alkaloid catabolism" EXACT [] synonym: "alkaloid degradation" EXACT [] is_a: GO:0009820 ! alkaloid metabolic process is_a: GO:0044270 ! cellular nitrogen compound catabolic process is_a: GO:1901565 ! organonitrogen compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:22315 ! alkaloid relationship: has_primary_input CHEBI:22315 ! alkaloid [Term] id: GO:0009880 name: embryonic pattern specification namespace: biological_process def: "The process that results in the patterns of cell differentiation that will arise in an embryo." [GOC:go_curators, ISBN:0521436125] synonym: "embryonic pattern biosynthesis" BROAD [] synonym: "embryonic pattern formation" BROAD [] synonym: "ventral/lateral system" RELATED [] is_a: GO:0007389 ! pattern specification process relationship: part_of GO:0009790 ! embryo development [Term] id: GO:0009887 name: animal organ morphogenesis namespace: biological_process def: "Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." [GOC:dgh, GOC:go_curators, ISBN:0471245208, ISBN:0721662544] synonym: "histogenesis and organogenesis" BROAD [] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000062 ! organ relationship: part_of GO:0048513 ! animal organ development relationship: results_in_morphogenesis_of UBERON:0000062 ! organ [Term] id: GO:0009888 name: tissue development namespace: biological_process def: "The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure." [ISBN:0471245208] synonym: "histogenesis" EXACT [] synonym: "histogenesis and organogenesis" BROAD [] xref: Wikipedia:Histogenesis is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000479 ! tissue relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota relationship: results_in_development_of UBERON:0000479 ! tissue property_value: RO:0002161 NCBITaxon:147554 property_value: RO:0002161 NCBITaxon:33630 property_value: RO:0002161 NCBITaxon:33682 property_value: RO:0002161 NCBITaxon:38254 property_value: RO:0002161 NCBITaxon:4891 [Term] id: GO:0009889 name: regulation of biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances." [GOC:go_curators] synonym: "regulation of anabolism" EXACT [] synonym: "regulation of biosynthesis" EXACT [] synonym: "regulation of formation" EXACT [] synonym: "regulation of synthesis" EXACT [] is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0009058 ! biosynthetic process relationship: regulates GO:0009058 ! biosynthetic process [Term] id: GO:0009890 name: negative regulation of biosynthetic process namespace: biological_process def: "Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances." [GOC:go_curators] synonym: "down regulation of biosynthetic process" EXACT [] synonym: "down-regulation of biosynthetic process" EXACT [] synonym: "downregulation of biosynthetic process" EXACT [] synonym: "inhibition of biosynthetic process" NARROW [] synonym: "negative regulation of anabolism" EXACT [] synonym: "negative regulation of biosynthesis" EXACT [] synonym: "negative regulation of formation" EXACT [] synonym: "negative regulation of synthesis" EXACT [] is_a: GO:0009889 ! regulation of biosynthetic process is_a: GO:0009892 ! negative regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0009058 ! biosynthetic process relationship: negatively_regulates GO:0009058 ! biosynthetic process [Term] id: GO:0009891 name: positive regulation of biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances." [GOC:go_curators] synonym: "activation of biosynthetic process" NARROW [] synonym: "positive regulation of anabolism" EXACT [] synonym: "positive regulation of biosynthesis" EXACT [] synonym: "positive regulation of formation" EXACT [] synonym: "positive regulation of synthesis" EXACT [] synonym: "stimulation of biosynthetic process" NARROW [] synonym: "up regulation of biosynthetic process" EXACT [] synonym: "up-regulation of biosynthetic process" EXACT [] synonym: "upregulation of biosynthetic process" EXACT [] is_a: GO:0009889 ! regulation of biosynthetic process is_a: GO:0009893 ! positive regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0009058 ! biosynthetic process relationship: positively_regulates GO:0009058 ! biosynthetic process [Term] id: GO:0009892 name: negative regulation of metabolic process namespace: biological_process alt_id: GO:0044252 def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." [GOC:go_curators] synonym: "down regulation of metabolic process" EXACT [] synonym: "down-regulation of metabolic process" EXACT [] synonym: "downregulation of metabolic process" EXACT [] synonym: "inhibition of metabolic process" NARROW [] synonym: "inhibition of organismal metabolic process" NARROW [] synonym: "negative regulation of metabolism" EXACT [] synonym: "negative regulation of multicellular organismal metabolic process" NARROW [] synonym: "negative regulation of organismal metabolism" EXACT [] is_a: GO:0019222 ! regulation of metabolic process is_a: GO:0048519 ! negative regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0008152 ! metabolic process relationship: negatively_regulates GO:0008152 ! metabolic process [Term] id: GO:0009893 name: positive regulation of metabolic process namespace: biological_process alt_id: GO:0044253 def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." [GOC:go_curators] synonym: "activation of metabolic process" NARROW [] synonym: "positive regulation of metabolism" EXACT [] synonym: "positive regulation of multicellular organismal metabolic process" NARROW [] synonym: "positive regulation of organismal metabolism" NARROW [] synonym: "stimulation of metabolic process" NARROW [] synonym: "stimulation of organismal metabolic process" NARROW [] synonym: "up regulation of metabolic process" EXACT [] synonym: "up-regulation of metabolic process" EXACT [] synonym: "up-regulation of organismal metabolic process" NARROW [] synonym: "upregulation of metabolic process" EXACT [] is_a: GO:0019222 ! regulation of metabolic process is_a: GO:0048518 ! positive regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0008152 ! metabolic process relationship: positively_regulates GO:0008152 ! metabolic process [Term] id: GO:0009894 name: regulation of catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances." [GOC:go_curators] synonym: "regulation of breakdown" EXACT [] synonym: "regulation of catabolism" EXACT [] synonym: "regulation of degradation" EXACT [] is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0009056 ! catabolic process relationship: regulates GO:0009056 ! catabolic process [Term] id: GO:0009895 name: negative regulation of catabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances." [GOC:go_curators] synonym: "down regulation of catabolic process" EXACT [] synonym: "down-regulation of catabolic process" EXACT [] synonym: "downregulation of catabolic process" EXACT [] synonym: "inhibition of catabolic process" NARROW [] synonym: "negative regulation of breakdown" EXACT [] synonym: "negative regulation of catabolism" EXACT [] synonym: "negative regulation of degradation" EXACT [] is_a: GO:0009892 ! negative regulation of metabolic process is_a: GO:0009894 ! regulation of catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0009056 ! catabolic process relationship: negatively_regulates GO:0009056 ! catabolic process [Term] id: GO:0009896 name: positive regulation of catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances." [GOC:go_curators] synonym: "activation of catabolic process" NARROW [] synonym: "positive regulation of breakdown" EXACT [] synonym: "positive regulation of catabolism" EXACT [] synonym: "positive regulation of degradation" EXACT [] synonym: "stimulation of catabolic process" NARROW [] synonym: "up regulation of catabolic process" EXACT [] synonym: "up-regulation of catabolic process" EXACT [] synonym: "upregulation of catabolic process" EXACT [] is_a: GO:0009893 ! positive regulation of metabolic process is_a: GO:0009894 ! regulation of catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0009056 ! catabolic process relationship: positively_regulates GO:0009056 ! catabolic process [Term] id: GO:0009913 name: epidermal cell differentiation namespace: biological_process alt_id: GO:0043355 def: "The process in which a relatively unspecialized cell acquires specialized features of an epidermal cell, any of the cells making up the epidermis." [GOC:dph, GOC:go_curators, GOC:mtg_sensu, GOC:sdb_2009, GOC:tb] synonym: "hypodermal cell differentiation" RELATED [GOC:kmv, GOC:rk] is_a: GO:0030855 ! epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000362 ! epidermal cell relationship: part_of GO:0008544 ! epidermis development relationship: results_in_acquisition_of_features_of CL:0000362 ! epidermal cell [Term] id: GO:0009914 name: hormone transport namespace: biological_process def: "The directed movement of hormones into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:tb] subset: goslim_pir is_a: GO:0006810 ! transport is_a: GO:0010817 ! regulation of hormone levels [Term] id: GO:0009948 name: anterior/posterior axis specification namespace: biological_process def: "The establishment, maintenance and elaboration of the anterior/posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "anterior/posterior axis determination" RELATED [GOC:dph] is_a: GO:0009798 ! axis specification relationship: part_of GO:0009952 ! anterior/posterior pattern specification [Term] id: GO:0009952 name: anterior/posterior pattern specification namespace: biological_process def: "The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism." [GOC:dph, GOC:go_curators, GOC:isa_complete, GOC:tb] synonym: "anterior/posterior pattern formation" RELATED [] is_a: GO:0003002 ! regionalization [Term] id: GO:0009966 name: regulation of signal transduction namespace: biological_process alt_id: GO:0035466 def: "Any process that modulates the frequency, rate or extent of signal transduction." [GOC:sm] synonym: "regulation of signaling pathway" RELATED [] synonym: "regulation of signalling pathway" RELATED [GOC:mah] is_a: GO:0010646 ! regulation of cell communication is_a: GO:0023051 ! regulation of signaling is_a: GO:0048583 ! regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007165 ! signal transduction relationship: regulates GO:0007165 ! signal transduction [Term] id: GO:0009967 name: positive regulation of signal transduction namespace: biological_process alt_id: GO:0035468 def: "Any process that activates or increases the frequency, rate or extent of signal transduction." [GOC:sm] synonym: "activation of signal transduction" NARROW [] synonym: "positive regulation of signaling pathway" RELATED [] synonym: "positive regulation of signalling pathway" RELATED [GOC:mah] synonym: "stimulation of signal transduction" NARROW [] synonym: "up regulation of signal transduction" EXACT [] synonym: "up-regulation of signal transduction" EXACT [] synonym: "upregulation of signal transduction" EXACT [] is_a: GO:0009966 ! regulation of signal transduction is_a: GO:0010647 ! positive regulation of cell communication is_a: GO:0023056 ! positive regulation of signaling is_a: GO:0048584 ! positive regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007165 ! signal transduction relationship: positively_regulates GO:0007165 ! signal transduction [Term] id: GO:0009968 name: negative regulation of signal transduction namespace: biological_process alt_id: GO:0035467 def: "Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction." [GOC:sm] synonym: "down regulation of signal transduction" EXACT [] synonym: "down-regulation of signal transduction" EXACT [] synonym: "downregulation of signal transduction" EXACT [] synonym: "inhibition of signal transduction" NARROW [] synonym: "negative regulation of signaling pathway" RELATED [] synonym: "negative regulation of signalling pathway" RELATED [GOC:mah] is_a: GO:0009966 ! regulation of signal transduction is_a: GO:0010648 ! negative regulation of cell communication is_a: GO:0023057 ! negative regulation of signaling is_a: GO:0048585 ! negative regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007165 ! signal transduction relationship: negatively_regulates GO:0007165 ! signal transduction [Term] id: GO:0009987 name: cellular process namespace: biological_process alt_id: GO:0008151 alt_id: GO:0044763 alt_id: GO:0050875 def: "Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:go_curators, GOC:isa_complete] comment: This term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term. subset: gocheck_do_not_annotate subset: goslim_plant synonym: "cell growth and/or maintenance" NARROW [] synonym: "cell physiology" EXACT [] synonym: "cellular physiological process" EXACT [] synonym: "single-organism cellular process" RELATED [] is_a: GO:0008150 ! biological process created_by: jl creation_date: 2012-12-11T16:56:55Z [Term] id: GO:0009994 name: oocyte differentiation namespace: biological_process def: "The process in which a relatively unspecialized immature germ cell acquires the specialized features of a mature female gamete." [GOC:go_curators, GOC:mtg_sensu] synonym: "oocyte cell differentiation" EXACT [] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000023 ! oocyte relationship: part_of GO:0048477 ! oogenesis relationship: results_in_acquisition_of_features_of CL:0000023 ! oocyte [Term] id: GO:0010001 name: glial cell differentiation namespace: biological_process alt_id: GO:0007404 alt_id: GO:0043360 def: "The process in which a relatively unspecialized cell acquires the specialized features of a glial cell." [GOC:go_curators, GOC:mtg_sensu] synonym: "glia cell differentiation" EXACT [] synonym: "neuroglia differentiation" EXACT [] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000125 ! glial cell relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0042063 ! gliogenesis relationship: results_in_acquisition_of_features_of CL:0000125 ! glial cell [Term] id: GO:0010002 name: cardioblast differentiation namespace: biological_process def: "The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:go_curators] synonym: "cardiac precursor cell differentiation" EXACT [GOC:mtg_heart] synonym: "cardioblast cell differentiation" EXACT [] synonym: "cardiomyocyte generation" RELATED [] is_a: GO:0035051 ! cardiocyte differentiation is_a: GO:0048863 ! stem cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0002664 ! cardioblast relationship: results_in_acquisition_of_features_of CL:0002664 ! cardioblast [Term] id: GO:0010032 name: meiotic chromosome condensation namespace: biological_process def: "Compaction of chromatin structure prior to meiosis in eukaryotic cells." [PMID:10072401] synonym: "chromosome condensation involved in meiotic cell cycle" EXACT [GOC:dph, GOC:tb] is_a: GO:0030261 ! chromosome condensation is_a: GO:0070192 ! chromosome organization involved in meiotic cell cycle intersection_of: GO:0030261 ! chromosome condensation intersection_of: part_of GO:0051321 ! meiotic cell cycle [Term] id: GO:0010033 name: response to organic substance namespace: biological_process alt_id: GO:1990367 def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus." [GOC:sm, PMID:23356676] synonym: "process resulting in tolerance to organic substance" NARROW [] is_a: GO:0042221 ! response to chemical intersection_of: GO:0042221 ! response to chemical intersection_of: has_primary_input CHEBI:50860 ! organic molecular entity relationship: has_primary_input CHEBI:50860 ! organic molecular entity [Term] id: GO:0010034 name: response to acetate namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus." [GOC:sm] is_a: GO:0010033 ! response to organic substance is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus intersection_of: has_primary_input CHEBI:30089 ! acetate relationship: has_primary_input CHEBI:30089 ! acetate [Term] id: GO:0010035 name: response to inorganic substance namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus." [GOC:sm] is_a: GO:0042221 ! response to chemical intersection_of: GO:0050896 ! response to stimulus intersection_of: has_primary_input CHEBI:24835 ! inorganic molecular entity relationship: has_primary_input CHEBI:24835 ! inorganic molecular entity [Term] id: GO:0010038 name: response to metal ion namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus." [GOC:sm] synonym: "heavy metal sensitivity/resistance" RELATED [] synonym: "response to heavy metal" NARROW [] synonym: "response to metal" EXACT [] is_a: GO:0010035 ! response to inorganic substance intersection_of: GO:0050896 ! response to stimulus intersection_of: has_primary_input CHEBI:25213 ! metal cation relationship: has_primary_input CHEBI:25213 ! metal cation [Term] id: GO:0010070 name: zygote asymmetric cell division namespace: biological_process def: "The division of the zygote into two daughter cells that will adopt developmentally distinct potentials." [GOC:tb] synonym: "zygote asymmetric cytokinesis" RELATED [] is_a: GO:0008356 ! asymmetric cell division intersection_of: GO:0008356 ! asymmetric cell division intersection_of: has_primary_input CL:0000365 ! animal zygote relationship: has_primary_input CL:0000365 ! animal zygote [Term] id: GO:0010160 name: formation of animal organ boundary namespace: biological_process alt_id: GO:0048862 def: "The regionalization process that specifies animal organ primordium boundaries resulting in a restriction of organogenesis to a limited spatial domain and keeping the organ separate from surrounding tissues." [GOC:dph, GOC:isa_complete, PMID:9611175] synonym: "organ boundary specification" EXACT [] is_a: GO:0003002 ! regionalization is_a: GO:0048859 ! formation of anatomical boundary intersection_of: GO:0048859 ! formation of anatomical boundary intersection_of: occurs_in UBERON:0000062 ! organ relationship: occurs_in UBERON:0000062 ! organ relationship: part_of GO:0048645 ! animal organ formation [Term] id: GO:0010171 name: body morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the soma are generated and organized." [GOC:ems, ISBN:0140512888] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000468 ! multicellular organism relationship: results_in_morphogenesis_of UBERON:0000468 ! multicellular organism [Term] id: GO:0010200 name: response to chitin namespace: biological_process def: "A process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chitin stimulus." [GOC:sm] is_a: GO:0010243 ! response to organonitrogen compound is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus intersection_of: has_primary_input CHEBI:17029 ! chitin relationship: has_primary_input CHEBI:17029 ! chitin [Term] id: GO:0010243 name: response to organonitrogen compound namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond." [PMID:9869419] synonym: "response to organic nitrogen" EXACT [] is_a: GO:0010033 ! response to organic substance is_a: GO:1901698 ! response to nitrogen compound intersection_of: GO:0050896 ! response to stimulus intersection_of: has_primary_input CHEBI:35352 ! organonitrogen compound relationship: has_primary_input CHEBI:35352 ! organonitrogen compound [Term] id: GO:0010256 name: endomembrane system organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system." [GOC:mah, GOC:sm] subset: goslim_drosophila synonym: "endomembrane organization" EXACT [] synonym: "endomembrane system organisation" EXACT [GOC:mah] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0012505 ! endomembrane system relationship: results_in_organization_of GO:0012505 ! endomembrane system [Term] id: GO:0010324 name: membrane invagination namespace: biological_process alt_id: GO:1902534 def: "The infolding of a membrane." [GOC:tb] subset: goslim_yeast synonym: "single-organism membrane invagination" RELATED [] is_a: GO:0061024 ! membrane organization created_by: jl creation_date: 2013-12-02T13:58:34Z [Term] id: GO:0010453 name: regulation of cell fate commitment namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field." [GOC:dph, GOC:tb] is_a: GO:0050793 ! regulation of developmental process is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0045165 ! cell fate commitment relationship: regulates GO:0045165 ! cell fate commitment [Term] id: GO:0010454 name: negative regulation of cell fate commitment namespace: biological_process def: "Any process that stops, prevents or reduces the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field." [GOC:dph, GOC:tb] is_a: GO:0010453 ! regulation of cell fate commitment is_a: GO:0045596 ! negative regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0045165 ! cell fate commitment relationship: negatively_regulates GO:0045165 ! cell fate commitment [Term] id: GO:0010455 name: positive regulation of cell fate commitment namespace: biological_process def: "Any process that activates, maintains or increases the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field." [GOC:dph, GOC:tb] is_a: GO:0010453 ! regulation of cell fate commitment is_a: GO:0045597 ! positive regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0045165 ! cell fate commitment relationship: positively_regulates GO:0045165 ! cell fate commitment [Term] id: GO:0010463 name: mesenchymal cell proliferation namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." [GOC:dph, GOC:tb] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0008019 ! mesenchymal cell relationship: acts_on_population_of CL:0008019 ! mesenchymal cell [Term] id: GO:0010464 name: regulation of mesenchymal cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." [GOC:dph, GOC:tb] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0010463 ! mesenchymal cell proliferation relationship: regulates GO:0010463 ! mesenchymal cell proliferation [Term] id: GO:0010467 name: gene expression namespace: biological_process def: "The process in which a gene's sequence is converted into a mature gene product (protein or RNA). This includes the production of an RNA transcript and its processing, as well as translation and maturation for protein-coding genes." [GOC:txnOH-2018, PMID:25934543, PMID:31580950] subset: goslim_flybase_ribbon xref: Wikipedia:Gene_expression is_a: GO:0009059 ! macromolecule biosynthetic process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22557" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/25419" xsd:anyURI [Term] id: GO:0010468 name: regulation of gene expression namespace: biological_process def: "Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)." [GOC:txnOH-2018] comment: This class covers any process that regulates the rate of production of a mature gene product, and so includes processes that regulate that rate by regulating the level, stability or availability of intermediates in the process of gene expression. For example, it covers any process that regulates the level, stability or availability of mRNA or circRNA for translation and thereby regulates the rate of production of the encoded protein via translation. synonym: "gene regulation" RELATED [GOC:cjm] synonym: "regulation of gene product expression" RELATED [] synonym: "regulation of protein expression" NARROW [] xref: Wikipedia:Regulation_of_gene_expression is_a: GO:0010556 ! regulation of macromolecule biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0010467 ! gene expression relationship: regulates GO:0010467 ! gene expression property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22557" xsd:anyURI [Term] id: GO:0010470 name: regulation of gastrulation namespace: biological_process def: "Any process that modulates the rate or extent of gastrulation. Gastrulation is the complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals." [GOC:dph, GOC:tb] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis is_a: GO:0045995 ! regulation of embryonic development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007369 ! gastrulation relationship: regulates GO:0007369 ! gastrulation [Term] id: GO:0010481 name: epidermal cell division namespace: biological_process def: "Any process resulting in the physical partitioning and separation of an epidermal cell, any of the cells making up the epidermis, into daughter cells." [PMID:17450124] synonym: "hypodermal cell division" RELATED [GOC:kmv, GOC:rk] is_a: GO:0051301 ! cell division intersection_of: GO:0051301 ! cell division intersection_of: has_primary_input CL:0000362 ! epidermal cell relationship: has_primary_input CL:0000362 ! epidermal cell [Term] id: GO:0010482 name: regulation of epidermal cell division namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the physical partitioning and separation of an epidermal cell into daughter cells. An epidermal cell is any of the cells that make up the epidermis." [PMID:17450124] synonym: "regulation of hypodermal cell division" RELATED [GOC:kmv, GOC:rk] is_a: GO:0051302 ! regulation of cell division intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0010481 ! epidermal cell division relationship: regulates GO:0010481 ! epidermal cell division [Term] id: GO:0010496 name: intercellular transport namespace: biological_process alt_id: GO:1902585 def: "The movement of substances between cells." [GOC:dhl] synonym: "single organism intercellular transport" RELATED [GOC:TermGenie] synonym: "single-organism intercellular transport" RELATED [] is_a: GO:0006810 ! transport is_a: GO:0009987 ! cellular process intersection_of: GO:0006810 ! transport intersection_of: has_target_end_location CL:0000000 ! cell intersection_of: has_target_start_location CL:0000000 ! cell intersection_of: results_in_transport_across GO:0005615 ! extracellular space relationship: has_target_end_location CL:0000000 ! cell relationship: has_target_start_location CL:0000000 ! cell relationship: results_in_transport_across GO:0005615 ! extracellular space created_by: jl creation_date: 2013-12-19T13:24:56Z [Term] id: GO:0010549 name: regulation of membrane disassembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of membrane disassembly." [GOC:dph, GOC:tb] is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030397 ! membrane disassembly relationship: regulates GO:0030397 ! membrane disassembly [Term] id: GO:0010556 name: regulation of macromolecule biosynthetic process namespace: biological_process def: "Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:dph, GOC:tb] is_a: GO:0031326 ! regulation of cellular biosynthetic process is_a: GO:0060255 ! regulation of macromolecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0009059 ! macromolecule biosynthetic process relationship: regulates GO:0009059 ! macromolecule biosynthetic process [Term] id: GO:0010557 name: positive regulation of macromolecule biosynthetic process namespace: biological_process def: "Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:dph, GOC:tb] is_a: GO:0010556 ! regulation of macromolecule biosynthetic process is_a: GO:0010604 ! positive regulation of macromolecule metabolic process is_a: GO:0031328 ! positive regulation of cellular biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0009059 ! macromolecule biosynthetic process relationship: positively_regulates GO:0009059 ! macromolecule biosynthetic process [Term] id: GO:0010558 name: negative regulation of macromolecule biosynthetic process namespace: biological_process def: "Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:dph, GOC:tb] is_a: GO:0010556 ! regulation of macromolecule biosynthetic process is_a: GO:0010605 ! negative regulation of macromolecule metabolic process is_a: GO:0031327 ! negative regulation of cellular biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0009059 ! macromolecule biosynthetic process relationship: negatively_regulates GO:0009059 ! macromolecule biosynthetic process [Term] id: GO:0010559 name: regulation of glycoprotein biosynthetic process namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:dph, GOC:tb] is_a: GO:0010556 ! regulation of macromolecule biosynthetic process is_a: GO:1903018 ! regulation of glycoprotein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0009101 ! glycoprotein biosynthetic process relationship: regulates GO:0009101 ! glycoprotein biosynthetic process [Term] id: GO:0010560 name: positive regulation of glycoprotein biosynthetic process namespace: biological_process def: "Any process that increases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:dph, GOC:tb] is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process is_a: GO:0010559 ! regulation of glycoprotein biosynthetic process is_a: GO:1903020 ! positive regulation of glycoprotein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0009101 ! glycoprotein biosynthetic process relationship: positively_regulates GO:0009101 ! glycoprotein biosynthetic process [Term] id: GO:0010561 name: negative regulation of glycoprotein biosynthetic process namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:dph, GOC:tb] is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process is_a: GO:0010559 ! regulation of glycoprotein biosynthetic process is_a: GO:1903019 ! negative regulation of glycoprotein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0009101 ! glycoprotein biosynthetic process relationship: negatively_regulates GO:0009101 ! glycoprotein biosynthetic process [Term] id: GO:0010562 name: positive regulation of phosphorus metabolic process namespace: biological_process def: "Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus." [GOC:dph, GOC:tb] is_a: GO:0031325 ! positive regulation of cellular metabolic process is_a: GO:0051174 ! regulation of phosphorus metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006793 ! phosphorus metabolic process relationship: positively_regulates GO:0006793 ! phosphorus metabolic process [Term] id: GO:0010563 name: negative regulation of phosphorus metabolic process namespace: biological_process def: "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus." [GOC:dph, GOC:tb] is_a: GO:0031324 ! negative regulation of cellular metabolic process is_a: GO:0051174 ! regulation of phosphorus metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006793 ! phosphorus metabolic process relationship: negatively_regulates GO:0006793 ! phosphorus metabolic process [Term] id: GO:0010564 name: regulation of cell cycle process namespace: biological_process def: "Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events." [GOC:dph, GOC:tb] is_a: GO:0051726 ! regulation of cell cycle intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0022402 ! cell cycle process relationship: regulates GO:0022402 ! cell cycle process [Term] id: GO:0010565 name: regulation of cellular ketone metabolic process namespace: biological_process def: "Any process that modulates the chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups." [GOC:dph, GOC:tb] is_a: GO:0031323 ! regulation of cellular metabolic process is_a: GO:0062012 ! regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0042180 ! cellular ketone metabolic process relationship: regulates GO:0042180 ! cellular ketone metabolic process [Term] id: GO:0010566 name: regulation of ketone biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a ketone, carried out by individual cells." [GOC:dph, GOC:tb] is_a: GO:0010565 ! regulation of cellular ketone metabolic process is_a: GO:0031326 ! regulation of cellular biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0042181 ! ketone biosynthetic process relationship: regulates GO:0042181 ! ketone biosynthetic process [Term] id: GO:0010567 name: regulation of ketone catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a ketone, carried out by individual cells." [GOC:dph, GOC:tb] is_a: GO:0010565 ! regulation of cellular ketone metabolic process is_a: GO:0031329 ! regulation of cellular catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0042182 ! ketone catabolic process relationship: regulates GO:0042182 ! ketone catabolic process [Term] id: GO:0010594 name: regulation of endothelial cell migration namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010632 ! regulation of epithelial cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0043542 ! endothelial cell migration relationship: regulates GO:0043542 ! endothelial cell migration [Term] id: GO:0010595 name: positive regulation of endothelial cell migration namespace: biological_process def: "Any process that increases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010594 ! regulation of endothelial cell migration is_a: GO:0010634 ! positive regulation of epithelial cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0043542 ! endothelial cell migration relationship: positively_regulates GO:0043542 ! endothelial cell migration [Term] id: GO:0010596 name: negative regulation of endothelial cell migration namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010594 ! regulation of endothelial cell migration is_a: GO:0010633 ! negative regulation of epithelial cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0043542 ! endothelial cell migration relationship: negatively_regulates GO:0043542 ! endothelial cell migration [Term] id: GO:0010604 name: positive regulation of macromolecule metabolic process namespace: biological_process def: "Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:dph, GOC:tb] is_a: GO:0009893 ! positive regulation of metabolic process is_a: GO:0060255 ! regulation of macromolecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0043170 ! macromolecule metabolic process relationship: positively_regulates GO:0043170 ! macromolecule metabolic process [Term] id: GO:0010605 name: negative regulation of macromolecule metabolic process namespace: biological_process def: "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:dph, GOC:tb] is_a: GO:0009892 ! negative regulation of metabolic process is_a: GO:0060255 ! regulation of macromolecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0043170 ! macromolecule metabolic process relationship: negatively_regulates GO:0043170 ! macromolecule metabolic process [Term] id: GO:0010608 name: post-transcriptional regulation of gene expression namespace: biological_process def: "Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript." [GOC:dph, GOC:tb] synonym: "posttranscriptional regulation of gene expression" EXACT [] is_a: GO:0010468 ! regulation of gene expression [Term] id: GO:0010611 name: regulation of cardiac muscle hypertrophy namespace: biological_process def: "Any process that modulates the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division." [GOC:dph, GOC:tb] is_a: GO:0014743 ! regulation of muscle hypertrophy is_a: GO:0043502 ! regulation of muscle adaptation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003300 ! cardiac muscle hypertrophy relationship: regulates GO:0003300 ! cardiac muscle hypertrophy [Term] id: GO:0010612 name: regulation of cardiac muscle adaptation namespace: biological_process def: "Any process that modulates the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors." [GOC:dph, GOC:tb] is_a: GO:0043502 ! regulation of muscle adaptation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0014887 ! cardiac muscle adaptation relationship: regulates GO:0014887 ! cardiac muscle adaptation [Term] id: GO:0010613 name: positive regulation of cardiac muscle hypertrophy namespace: biological_process def: "Any process that increases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010611 ! regulation of cardiac muscle hypertrophy is_a: GO:0014742 ! positive regulation of muscle hypertrophy intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0003300 ! cardiac muscle hypertrophy relationship: positively_regulates GO:0003300 ! cardiac muscle hypertrophy [Term] id: GO:0010614 name: negative regulation of cardiac muscle hypertrophy namespace: biological_process def: "Any process that decreases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010611 ! regulation of cardiac muscle hypertrophy is_a: GO:0014741 ! negative regulation of muscle hypertrophy intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0003300 ! cardiac muscle hypertrophy relationship: negatively_regulates GO:0003300 ! cardiac muscle hypertrophy [Term] id: GO:0010615 name: positive regulation of cardiac muscle adaptation namespace: biological_process def: "Any process that increases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010612 ! regulation of cardiac muscle adaptation is_a: GO:0014744 ! positive regulation of muscle adaptation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0014887 ! cardiac muscle adaptation relationship: positively_regulates GO:0014887 ! cardiac muscle adaptation [Term] id: GO:0010616 name: negative regulation of cardiac muscle adaptation namespace: biological_process def: "Any process that decreases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010612 ! regulation of cardiac muscle adaptation is_a: GO:0014745 ! negative regulation of muscle adaptation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0014887 ! cardiac muscle adaptation relationship: negatively_regulates GO:0014887 ! cardiac muscle adaptation [Term] id: GO:0010623 name: programmed cell death involved in cell development namespace: biological_process def: "The activation of endogenous cellular processes that result in the death of a cell as part of its development." [GOC:dph, GOC:mtg_apoptosis, GOC:tb] comment: This process is part of the natural developmental program of some cell types, but it does not always happen as part of the development or shaping of a gross anatomical structure. synonym: "developmental programmed cell death" BROAD [] synonym: "programmed cell death involved in development" BROAD [] is_a: GO:0012501 ! programmed cell death is_a: GO:0048869 ! cellular developmental process intersection_of: GO:0012501 ! programmed cell death intersection_of: part_of GO:0048468 ! cell development relationship: part_of GO:0048468 ! cell development [Term] id: GO:0010628 name: positive regulation of gene expression namespace: biological_process def: "Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)." [GOC:txnOH-2018] is_a: GO:0010468 ! regulation of gene expression is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0010467 ! gene expression relationship: positively_regulates GO:0010467 ! gene expression property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22557" xsd:anyURI [Term] id: GO:0010629 name: negative regulation of gene expression namespace: biological_process def: "Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)." [GOC:txnOH-2018] comment: This term covers any process that negatively regulates the rate of production of a mature gene product, and so includes processes that negatively regulate that rate by reducing the level, stability or availability of intermediates in the process of gene expression. For example, it covers any process that reduces the level, stability or availability of mRNA or circRNA for translation and thereby reduces the rate of production of the encoded protein via translation. synonym: "gene silencing" RELATED [] is_a: GO:0010468 ! regulation of gene expression is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0010467 ! gene expression relationship: negatively_regulates GO:0010467 ! gene expression property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22557" xsd:anyURI [Term] id: GO:0010631 name: epithelial cell migration namespace: biological_process def: "The orderly movement of an epithelial cell from one site to another, often during the development of a multicellular organism." [GOC:ascb_2009, GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0001667 ! ameboidal-type cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000066 ! epithelial cell relationship: part_of GO:0090132 ! epithelium migration relationship: results_in_movement_of CL:0000066 ! epithelial cell [Term] id: GO:0010632 name: regulation of epithelial cell migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of epithelial cell migration." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0030334 ! regulation of cell migration is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0010631 ! epithelial cell migration relationship: regulates GO:0010631 ! epithelial cell migration [Term] id: GO:0010633 name: negative regulation of epithelial cell migration namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell migration." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010632 ! regulation of epithelial cell migration is_a: GO:0030336 ! negative regulation of cell migration is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0010631 ! epithelial cell migration relationship: negatively_regulates GO:0010631 ! epithelial cell migration [Term] id: GO:0010634 name: positive regulation of epithelial cell migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of epithelial cell migration." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010632 ! regulation of epithelial cell migration is_a: GO:0030335 ! positive regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0010631 ! epithelial cell migration relationship: positively_regulates GO:0010631 ! epithelial cell migration [Term] id: GO:0010638 name: positive regulation of organelle organization namespace: biological_process def: "Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle." [GOC:dph, GOC:tb] synonym: "positive regulation of organelle organisation" EXACT [GOC:mah] synonym: "positive regulation of organelle organization and biogenesis" RELATED [GOC:mah] is_a: GO:0033043 ! regulation of organelle organization is_a: GO:0051130 ! positive regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006996 ! organelle organization relationship: positively_regulates GO:0006996 ! organelle organization [Term] id: GO:0010639 name: negative regulation of organelle organization namespace: biological_process def: "Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle." [GOC:dph, GOC:tb] synonym: "negative regulation of organelle organisation" EXACT [GOC:mah] synonym: "negative regulation of organelle organization and biogenesis" RELATED [GOC:mah] is_a: GO:0033043 ! regulation of organelle organization is_a: GO:0051129 ! negative regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006996 ! organelle organization relationship: negatively_regulates GO:0006996 ! organelle organization [Term] id: GO:0010646 name: regulation of cell communication namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:dph, GOC:tb] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007154 ! cell communication relationship: regulates GO:0007154 ! cell communication [Term] id: GO:0010647 name: positive regulation of cell communication namespace: biological_process def: "Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:dph, GOC:tb] is_a: GO:0010646 ! regulation of cell communication is_a: GO:0048522 ! positive regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007154 ! cell communication relationship: positively_regulates GO:0007154 ! cell communication [Term] id: GO:0010648 name: negative regulation of cell communication namespace: biological_process def: "Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:dph, GOC:tb] is_a: GO:0010646 ! regulation of cell communication is_a: GO:0048523 ! negative regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007154 ! cell communication relationship: negatively_regulates GO:0007154 ! cell communication [Term] id: GO:0010656 name: negative regulation of muscle cell apoptotic process namespace: biological_process def: "Any process that decreases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death." [GOC:dph, GOC:mtg_apoptosis, GOC:tb] synonym: "negative regulation of muscle cell apoptosis" NARROW [] is_a: GO:0010660 ! regulation of muscle cell apoptotic process is_a: GO:0043066 ! negative regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0010657 ! muscle cell apoptotic process relationship: negatively_regulates GO:0010657 ! muscle cell apoptotic process [Term] id: GO:0010657 name: muscle cell apoptotic process namespace: biological_process def: "A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a muscle cell and result in its death. A muscle cell is a mature contractile cell, commonly known as a myocyte, that forms one of three kinds of muscle." [CL:0000187, GOC:dph, GOC:mtg_apoptosis, GOC:tb] synonym: "muscle cell apoptosis" NARROW [] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000187 ! muscle cell relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: occurs_in CL:0000187 ! muscle cell relationship: only_in_taxon NCBITaxon:33208 ! Metazoa [Term] id: GO:0010658 name: striated muscle cell apoptotic process namespace: biological_process def: "A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a striated muscle cell and result in its death. Striated muscle cells make up striated muscle fibers which are divided by transverse bands into striations." [CL:0000737, GOC:dph, GOC:mtg_apoptosis, GOC:tb] synonym: "striated muscle cell apoptosis" NARROW [] is_a: GO:0010657 ! muscle cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000737 ! striated muscle cell relationship: occurs_in CL:0000737 ! striated muscle cell [Term] id: GO:0010659 name: cardiac muscle cell apoptotic process namespace: biological_process def: "A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a cardiac muscle cell and result in its death. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction." [CL:0000746, GOC:dph, GOC:mtg_apoptosis, GOC:tb] synonym: "cardiac muscle cell apoptosis" NARROW [] is_a: GO:0010658 ! striated muscle cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000746 ! cardiac muscle cell relationship: occurs_in CL:0000746 ! cardiac muscle cell [Term] id: GO:0010660 name: regulation of muscle cell apoptotic process namespace: biological_process def: "Any process that modulates the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death." [GOC:dph, GOC:mtg_apoptosis, GOC:tb] synonym: "regulation of muscle cell apoptosis" NARROW [] is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0010657 ! muscle cell apoptotic process relationship: regulates GO:0010657 ! muscle cell apoptotic process [Term] id: GO:0010661 name: positive regulation of muscle cell apoptotic process namespace: biological_process def: "Any process that increases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death." [GOC:dph, GOC:mtg_apoptosis, GOC:tb] synonym: "positive regulation of muscle cell apoptosis" NARROW [] is_a: GO:0010660 ! regulation of muscle cell apoptotic process is_a: GO:0043065 ! positive regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0010657 ! muscle cell apoptotic process relationship: positively_regulates GO:0010657 ! muscle cell apoptotic process [Term] id: GO:0010662 name: regulation of striated muscle cell apoptotic process namespace: biological_process def: "Any process that modulates the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death." [GOC:dph, GOC:mtg_apoptosis, GOC:tb] synonym: "regulation of striated muscle cell apoptosis" NARROW [] is_a: GO:0010660 ! regulation of muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0010658 ! striated muscle cell apoptotic process relationship: regulates GO:0010658 ! striated muscle cell apoptotic process [Term] id: GO:0010663 name: positive regulation of striated muscle cell apoptotic process namespace: biological_process def: "Any process that increases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death." [GOC:dph, GOC:mtg_apoptosis, GOC:tb] synonym: "positive regulation of striated muscle cell apoptosis" NARROW [] is_a: GO:0010661 ! positive regulation of muscle cell apoptotic process is_a: GO:0010662 ! regulation of striated muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0010658 ! striated muscle cell apoptotic process relationship: positively_regulates GO:0010658 ! striated muscle cell apoptotic process [Term] id: GO:0010664 name: negative regulation of striated muscle cell apoptotic process namespace: biological_process def: "Any process that decreases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death." [GOC:BHF, GOC:dph, GOC:mtg_apoptosis, GOC:rl, GOC:tb] synonym: "down regulation of striated muscle cell apoptosis" EXACT [GOC:dph, GOC:rl, GOC:tb] synonym: "down-regulation of striated muscle cell apoptosis" EXACT [GOC:dph, GOC:rl, GOC:tb] synonym: "downregulation of striated muscle cell apoptosis" EXACT [GOC:dph, GOC:rl, GOC:tb] synonym: "inhibition of striated muscle cell apoptosis" NARROW [GOC:dph, GOC:rl, GOC:tb] synonym: "negative regulation of striated muscle cell apoptosis" NARROW [] is_a: GO:0010656 ! negative regulation of muscle cell apoptotic process is_a: GO:0010662 ! regulation of striated muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0010658 ! striated muscle cell apoptotic process relationship: negatively_regulates GO:0010658 ! striated muscle cell apoptotic process [Term] id: GO:0010665 name: regulation of cardiac muscle cell apoptotic process namespace: biological_process def: "Any process that modulates the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death." [GOC:dph, GOC:mtg_apoptosis, GOC:tb] synonym: "regulation of cardiac muscle cell apoptosis" NARROW [] is_a: GO:0010662 ! regulation of striated muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0010659 ! cardiac muscle cell apoptotic process relationship: regulates GO:0010659 ! cardiac muscle cell apoptotic process [Term] id: GO:0010666 name: positive regulation of cardiac muscle cell apoptotic process namespace: biological_process def: "Any process that increases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death." [GOC:dph, GOC:mtg_apoptosis, GOC:tb] synonym: "positive regulation of cardiac muscle cell apoptosis" NARROW [] is_a: GO:0010663 ! positive regulation of striated muscle cell apoptotic process is_a: GO:0010665 ! regulation of cardiac muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0010659 ! cardiac muscle cell apoptotic process relationship: positively_regulates GO:0010659 ! cardiac muscle cell apoptotic process [Term] id: GO:0010667 name: negative regulation of cardiac muscle cell apoptotic process namespace: biological_process def: "Any process that decreases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death." [GOC:BHF, GOC:dph, GOC:mtg_apoptosis, GOC:rl, GOC:tb] synonym: "down regulation of cardiac muscle cell apoptosis" EXACT [GOC:dph, GOC:rl, GOC:tb] synonym: "down-regulation of cardiac muscle cell apoptosis" EXACT [GOC:dph, GOC:rl, GOC:tb] synonym: "downregulation of cardiac muscle cell apoptosis" EXACT [GOC:dph, GOC:rl, GOC:tb] synonym: "inhibition of cardiac muscle cell apoptosis" NARROW [GOC:dph, GOC:rl, GOC:tb] synonym: "negative regulation of cardiac muscle cell apoptosis" NARROW [] is_a: GO:0010664 ! negative regulation of striated muscle cell apoptotic process is_a: GO:0010665 ! regulation of cardiac muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0010659 ! cardiac muscle cell apoptotic process relationship: negatively_regulates GO:0010659 ! cardiac muscle cell apoptotic process [Term] id: GO:0010668 name: ectodermal cell differentiation namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an ectodermal cell. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GOC:dph, GOC:tb] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000221 ! ectodermal cell relationship: part_of GO:0007398 ! ectoderm development relationship: results_in_acquisition_of_features_of CL:0000221 ! ectodermal cell [Term] id: GO:0010700 name: negative regulation of norepinephrine secretion namespace: biological_process def: "Any process that decreases the frequency, rate or extent of the regulated release of norepinephrine." [GOC:dph, GOC:tb] is_a: GO:0014061 ! regulation of norepinephrine secretion is_a: GO:0033604 ! negative regulation of catecholamine secretion intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048243 ! norepinephrine secretion relationship: negatively_regulates GO:0048243 ! norepinephrine secretion [Term] id: GO:0010701 name: positive regulation of norepinephrine secretion namespace: biological_process def: "Any process that increases the frequency, rate or extent of the regulated release of norepinephrine." [GOC:dph, GOC:tb] is_a: GO:0014061 ! regulation of norepinephrine secretion is_a: GO:0033605 ! positive regulation of catecholamine secretion intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048243 ! norepinephrine secretion relationship: positively_regulates GO:0048243 ! norepinephrine secretion [Term] id: GO:0010710 name: regulation of collagen catabolic process namespace: biological_process def: "Any process that modulates the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix." [GOC:BHF, GOC:dph, GOC:tb] synonym: "regulation of collagen breakdown" EXACT [GOC:dph, GOC:tb] synonym: "regulation of collagen catabolism" EXACT [GOC:dph, GOC:tb] synonym: "regulation of collagen degradation" EXACT [GOC:dph, GOC:tb] is_a: GO:0009894 ! regulation of catabolic process is_a: GO:0010712 ! regulation of collagen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030574 ! collagen catabolic process relationship: regulates GO:0030574 ! collagen catabolic process [Term] id: GO:0010711 name: negative regulation of collagen catabolic process namespace: biological_process def: "Any process that decreases the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix." [GOC:BHF, GOC:dph, GOC:tb] synonym: "down regulation of collagen catabolic process" EXACT [GOC:dph, GOC:tb] synonym: "down-regulation of collagen catabolic process" EXACT [GOC:dph, GOC:tb] synonym: "downregulation of collagen catabolic process" EXACT [GOC:dph, GOC:tb] synonym: "inhibition of collagen catabolic process" NARROW [GOC:dph, GOC:tb] synonym: "negative regulation of collagen breakdown" EXACT [GOC:dph, GOC:tb] synonym: "negative regulation of collagen catabolism" EXACT [GOC:dph, GOC:tb] synonym: "negative regulation of collagen degradation" EXACT [GOC:dph, GOC:tb] is_a: GO:0009895 ! negative regulation of catabolic process is_a: GO:0010710 ! regulation of collagen catabolic process is_a: GO:0010713 ! negative regulation of collagen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030574 ! collagen catabolic process relationship: negatively_regulates GO:0030574 ! collagen catabolic process [Term] id: GO:0010712 name: regulation of collagen metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." [GOC:dph, GOC:tb] synonym: "regulation of collagen metabolism" EXACT [GOC:dph, GOC:tb] is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0032963 ! collagen metabolic process relationship: regulates GO:0032963 ! collagen metabolic process [Term] id: GO:0010713 name: negative regulation of collagen metabolic process namespace: biological_process def: "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." [GOC:dph, GOC:tb] is_a: GO:0009892 ! negative regulation of metabolic process is_a: GO:0010712 ! regulation of collagen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0032963 ! collagen metabolic process relationship: negatively_regulates GO:0032963 ! collagen metabolic process [Term] id: GO:0010714 name: positive regulation of collagen metabolic process namespace: biological_process def: "Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." [GOC:dph, GOC:tb] synonym: "positive regulation of collagen metabolism" EXACT [GOC:dph, GOC:tb] is_a: GO:0009893 ! positive regulation of metabolic process is_a: GO:0010712 ! regulation of collagen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0032963 ! collagen metabolic process relationship: positively_regulates GO:0032963 ! collagen metabolic process [Term] id: GO:0010715 name: regulation of extracellular matrix disassembly namespace: biological_process def: "Any process that modulates the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix." [GOC:BHF, GOC:dph, GOC:tb] synonym: "regulation of extracellular matrix breakdown" EXACT [GOC:dph, GOC:tb] synonym: "regulation of extracellular matrix degradation" EXACT [GOC:dph, GOC:tb] is_a: GO:1903053 ! regulation of extracellular matrix organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0022617 ! extracellular matrix disassembly relationship: regulates GO:0022617 ! extracellular matrix disassembly [Term] id: GO:0010716 name: negative regulation of extracellular matrix disassembly namespace: biological_process def: "Any process that decreases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix." [GOC:BHF, GOC:dph, GOC:tb] synonym: "down regulation of extracellular matrix disassembly" EXACT [GOC:dph, GOC:tb] synonym: "down-regulation of extracellular matrix disassembly" EXACT [GOC:dph, GOC:tb] synonym: "downregulation of extracellular matrix disassembly" EXACT [GOC:dph, GOC:tb] synonym: "inhibition of extracellular matrix disassembly" NARROW [GOC:dph, GOC:tb] synonym: "negative regulation of extracellular matrix breakdown" EXACT [GOC:dph, GOC:tb] synonym: "negative regulation of extracellular matrix degradation" EXACT [GOC:dph, GOC:tb] is_a: GO:0010715 ! regulation of extracellular matrix disassembly is_a: GO:1903054 ! negative regulation of extracellular matrix organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0022617 ! extracellular matrix disassembly relationship: negatively_regulates GO:0022617 ! extracellular matrix disassembly [Term] id: GO:0010717 name: regulation of epithelial to mesenchymal transition namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001837 ! epithelial to mesenchymal transition relationship: regulates GO:0001837 ! epithelial to mesenchymal transition [Term] id: GO:0010718 name: positive regulation of epithelial to mesenchymal transition namespace: biological_process def: "Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010717 ! regulation of epithelial to mesenchymal transition is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001837 ! epithelial to mesenchymal transition relationship: positively_regulates GO:0001837 ! epithelial to mesenchymal transition [Term] id: GO:0010719 name: negative regulation of epithelial to mesenchymal transition namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010717 ! regulation of epithelial to mesenchymal transition is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001837 ! epithelial to mesenchymal transition relationship: negatively_regulates GO:0001837 ! epithelial to mesenchymal transition [Term] id: GO:0010720 name: positive regulation of cell development namespace: biological_process def: "Any process that increases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0060284 ! regulation of cell development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048468 ! cell development relationship: positively_regulates GO:0048468 ! cell development [Term] id: GO:0010721 name: negative regulation of cell development namespace: biological_process def: "Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0060284 ! regulation of cell development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048468 ! cell development relationship: negatively_regulates GO:0048468 ! cell development [Term] id: GO:0010761 name: fibroblast migration namespace: biological_process def: "Cell migration that is accomplished by extension and retraction of a fibroblast pseudopodium. A fibroblast is a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules." [GOC:BHF, GOC:dph, GOC:tb] synonym: "fibroblast cell migration" EXACT [GOC:dph] is_a: GO:0001667 ! ameboidal-type cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000057 ! fibroblast relationship: results_in_movement_of CL:0000057 ! fibroblast [Term] id: GO:0010762 name: regulation of fibroblast migration namespace: biological_process def: "Any process that modulates the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium." [GOC:dph, GOC:tb] synonym: "regulation of fibroblast cell migration" EXACT [GOC:dph] is_a: GO:0030334 ! regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0010761 ! fibroblast migration relationship: regulates GO:0010761 ! fibroblast migration [Term] id: GO:0010763 name: positive regulation of fibroblast migration namespace: biological_process def: "Any process that increases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium." [GOC:BHF, GOC:dph, GOC:tb] synonym: "positive regulation of fibroblast cell migration" EXACT [GOC:dph] is_a: GO:0010762 ! regulation of fibroblast migration is_a: GO:0030335 ! positive regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0010761 ! fibroblast migration relationship: positively_regulates GO:0010761 ! fibroblast migration [Term] id: GO:0010764 name: negative regulation of fibroblast migration namespace: biological_process def: "Any process that decreases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium." [GOC:dph, GOC:tb] synonym: "negative regulation of fibroblast cell migration" EXACT [GOC:dph] is_a: GO:0010762 ! regulation of fibroblast migration is_a: GO:0030336 ! negative regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0010761 ! fibroblast migration relationship: negatively_regulates GO:0010761 ! fibroblast migration [Term] id: GO:0010765 name: positive regulation of sodium ion transport namespace: biological_process def: "Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:tb] is_a: GO:0002028 ! regulation of sodium ion transport is_a: GO:0043270 ! positive regulation of monoatomic ion transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006814 ! sodium ion transport relationship: positively_regulates GO:0006814 ! sodium ion transport [Term] id: GO:0010766 name: negative regulation of sodium ion transport namespace: biological_process def: "Any process that decreases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:tb] is_a: GO:0002028 ! regulation of sodium ion transport is_a: GO:0043271 ! negative regulation of monoatomic ion transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006814 ! sodium ion transport relationship: negatively_regulates GO:0006814 ! sodium ion transport [Term] id: GO:0010770 name: positive regulation of cell morphogenesis namespace: biological_process def: "Any process that increases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history." [GOC:dph, GOC:tb] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0022604 ! regulation of cell morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0000902 ! cell morphogenesis relationship: positively_regulates GO:0000902 ! cell morphogenesis property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24299" xsd:anyURI [Term] id: GO:0010771 name: negative regulation of cell morphogenesis namespace: biological_process def: "Any process that decreases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history." [GOC:dph, GOC:tb] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0022604 ! regulation of cell morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0000902 ! cell morphogenesis relationship: negatively_regulates GO:0000902 ! cell morphogenesis property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24299" xsd:anyURI [Term] id: GO:0010817 name: regulation of hormone levels namespace: biological_process def: "Any process that modulates the levels of hormone within an organism or a tissue. A hormone is any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action." [GOC:BHF, GOC:dph, GOC:tb] [Term] id: GO:0010827 name: regulation of glucose transmembrane transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:tb] synonym: "regulation of glucose transport" RELATED [] is_a: GO:0034762 ! regulation of transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1904659 ! glucose transmembrane transport relationship: regulates GO:1904659 ! glucose transmembrane transport [Term] id: GO:0010828 name: positive regulation of glucose transmembrane transport namespace: biological_process def: "Any process that increases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:BHF, GOC:dph, GOC:tb] synonym: "positive regulation of glucose transport" RELATED [] is_a: GO:0010827 ! regulation of glucose transmembrane transport is_a: GO:0034764 ! positive regulation of transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1904659 ! glucose transmembrane transport relationship: positively_regulates GO:1904659 ! glucose transmembrane transport [Term] id: GO:0010829 name: negative regulation of glucose transmembrane transport namespace: biological_process def: "Any process that decreases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:BHF, GOC:dph, GOC:tb] synonym: "negative regulation of glucose transport" RELATED [] is_a: GO:0010827 ! regulation of glucose transmembrane transport is_a: GO:0034763 ! negative regulation of transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1904659 ! glucose transmembrane transport relationship: negatively_regulates GO:1904659 ! glucose transmembrane transport [Term] id: GO:0010830 name: regulation of myotube differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." [GOC:dph, GOC:tb] is_a: GO:0051153 ! regulation of striated muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0014902 ! myotube differentiation relationship: regulates GO:0014902 ! myotube differentiation [Term] id: GO:0010831 name: positive regulation of myotube differentiation namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." [GOC:dph, GOC:tb] is_a: GO:0010830 ! regulation of myotube differentiation is_a: GO:0051155 ! positive regulation of striated muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0014902 ! myotube differentiation relationship: positively_regulates GO:0014902 ! myotube differentiation [Term] id: GO:0010832 name: negative regulation of myotube differentiation namespace: biological_process def: "Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." [GOC:dph, GOC:tb] is_a: GO:0010830 ! regulation of myotube differentiation is_a: GO:0051154 ! negative regulation of striated muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0014902 ! myotube differentiation relationship: negatively_regulates GO:0014902 ! myotube differentiation [Term] id: GO:0010842 name: retina layer formation namespace: biological_process def: "The process in which the vertebrate retina is organized into three laminae: the outer nuclear layer (ONL), which contains photoreceptor nuclei; the inner nuclear layer (INL), which contains amacrine, bipolar and horizontal cells; and the retinal ganglion cell (RGC) layer. Between the inner and outer nuclear layers, the outer plexiform layer (OPL) contains connections between the photoreceptors and bipolar and horizontal cells. The inner plexiform layer (IPL) is positioned between the INL and the ganglion cell layer and contains the dendrites of RGCs and processes of bipolar and amacrine cells. Spanning all layers of the retina are the radially oriented Mueller glia." [GOC:ascb_2009, GOC:dph, GOC:tb, PMID:1270266] synonym: "retinal lamination" EXACT [GOC:dph, GOC:tb] synonym: "retinal layer formation" EXACT [GOC:dph, GOC:tb] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0001781 ! layer of retina relationship: part_of GO:0003407 ! neural retina development relationship: part_of GO:0060042 ! retina morphogenesis in camera-type eye relationship: results_in_formation_of_anatomical_entity UBERON:0001781 ! layer of retina [Term] id: GO:0010876 name: lipid localization namespace: biological_process def: "Any process in which a lipid is transported to, or maintained in, a specific location." [GOC:BHF, GOC:dph, GOC:tb] synonym: "lipid localisation" EXACT [GOC:mah] is_a: GO:0033036 ! macromolecule localization intersection_of: GO:0033036 ! macromolecule localization intersection_of: has_primary_input CHEBI:18059 ! lipid relationship: has_primary_input CHEBI:18059 ! lipid [Term] id: GO:0010893 name: positive regulation of steroid biosynthetic process namespace: biological_process def: "Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus." [GOC:tb] is_a: GO:0045940 ! positive regulation of steroid metabolic process is_a: GO:0046889 ! positive regulation of lipid biosynthetic process is_a: GO:0050810 ! regulation of steroid biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006694 ! steroid biosynthetic process relationship: positively_regulates GO:0006694 ! steroid biosynthetic process [Term] id: GO:0010894 name: negative regulation of steroid biosynthetic process namespace: biological_process def: "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus." [GOC:BHF, GOC:tb] is_a: GO:0045939 ! negative regulation of steroid metabolic process is_a: GO:0050810 ! regulation of steroid biosynthetic process is_a: GO:0051055 ! negative regulation of lipid biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006694 ! steroid biosynthetic process relationship: negatively_regulates GO:0006694 ! steroid biosynthetic process [Term] id: GO:0010906 name: regulation of glucose metabolic process namespace: biological_process def: "Any process that modulates the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose." [GOC:BHF, GOC:tb] synonym: "regulation of glucose metabolism" EXACT [GOC:tb] is_a: GO:0006109 ! regulation of carbohydrate metabolic process is_a: GO:0062012 ! regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006006 ! glucose metabolic process relationship: regulates GO:0006006 ! glucose metabolic process [Term] id: GO:0010907 name: positive regulation of glucose metabolic process namespace: biological_process def: "Any process that increases the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose." [GOC:BHF, GOC:tb] synonym: "positive regulation of glucose metabolism" EXACT [GOC:tb] is_a: GO:0010906 ! regulation of glucose metabolic process is_a: GO:0045913 ! positive regulation of carbohydrate metabolic process is_a: GO:0062013 ! positive regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006006 ! glucose metabolic process relationship: positively_regulates GO:0006006 ! glucose metabolic process [Term] id: GO:0010927 name: cellular component assembly involved in morphogenesis namespace: biological_process def: "The cellular component assembly that is part of the initial shaping of the component during its developmental progression." [GOC:dph, GOC:tb] is_a: GO:0022607 ! cellular component assembly is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0022607 ! cellular component assembly intersection_of: part_of GO:0009653 ! anatomical structure morphogenesis relationship: part_of GO:0032989 ! cellular anatomical entity morphogenesis [Term] id: GO:0010937 name: regulation of cytoplasmic microtubule depolymerization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cytoplasmic microtubule depolymerization." [GOC:dph, GOC:tb] is_a: GO:0031114 ! regulation of microtubule depolymerization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0010938 ! cytoplasmic microtubule depolymerization relationship: regulates GO:0010938 ! cytoplasmic microtubule depolymerization [Term] id: GO:0010938 name: cytoplasmic microtubule depolymerization namespace: biological_process def: "The removal of tubulin heterodimers from one or both ends of a cytoplasmic microtubule." [GOC:dph, GOC:tb] is_a: GO:0007019 ! microtubule depolymerization is_a: GO:0031122 ! cytoplasmic microtubule organization intersection_of: GO:0007019 ! microtubule depolymerization intersection_of: occurs_in GO:0005737 ! cytoplasm relationship: occurs_in GO:0005737 ! cytoplasm [Term] id: GO:0010948 name: negative regulation of cell cycle process namespace: biological_process def: "Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events." [GOC:dph, GOC:tb] is_a: GO:0010564 ! regulation of cell cycle process is_a: GO:0045786 ! negative regulation of cell cycle intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0022402 ! cell cycle process relationship: negatively_regulates GO:0022402 ! cell cycle process created_by: tb creation_date: 2009-04-27T09:53:22Z [Term] id: GO:0010959 name: regulation of metal ion transport namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of metal ion transport. Metal ion transport is the directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:tb] is_a: GO:0043269 ! regulation of monoatomic ion transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030001 ! metal ion transport relationship: regulates GO:0030001 ! metal ion transport created_by: tb creation_date: 2009-05-06T11:40:55Z [Term] id: GO:0010962 name: regulation of glucan biosynthetic process namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of glucan biosynthesis. Glucan biosynthetic processes are the chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues." [GOC:dph, GOC:tb] is_a: GO:0032885 ! regulation of polysaccharide biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0009250 ! glucan biosynthetic process relationship: regulates GO:0009250 ! glucan biosynthetic process created_by: tb creation_date: 2009-05-11T12:17:53Z [Term] id: GO:0010966 name: regulation of phosphate transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of phosphate transport. Phosphate transport is the directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:tb] is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006817 ! phosphate ion transport relationship: regulates GO:0006817 ! phosphate ion transport created_by: tb creation_date: 2009-05-20T11:42:50Z [Term] id: GO:0010968 name: regulation of microtubule nucleation namespace: biological_process def: "Any process that modulates the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell." [GOC:dph, GOC:tb] is_a: GO:0031113 ! regulation of microtubule polymerization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007020 ! microtubule nucleation relationship: regulates GO:0007020 ! microtubule nucleation created_by: tb creation_date: 2009-05-20T11:51:21Z [Term] id: GO:0010970 name: transport along microtubule namespace: biological_process def: "The movement of organelles or other particles from one location in the cell to another along microtubules, driven by motor activity." [GOC:dph, GOC:mah, GOC:tb] synonym: "establishment of localization by movement along microtubule" EXACT [GOC:dph] synonym: "microtubule-based transport" BROAD [] synonym: "movement along microtubule" EXACT [] is_a: GO:0007018 ! microtubule-based movement is_a: GO:0030705 ! cytoskeleton-dependent intracellular transport is_a: GO:0099111 ! microtubule-based transport intersection_of: GO:0006810 ! transport intersection_of: results_in_transport_along GO:0005874 ! microtubule relationship: results_in_transport_along GO:0005874 ! microtubule created_by: tb creation_date: 2009-05-27T10:56:08Z [Term] id: GO:0010975 name: regulation of neuron projection development namespace: biological_process def: "Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." [GOC:dph, GOC:tb] synonym: "regulation of neurite biosynthesis" NARROW [GOC:mah] synonym: "regulation of neurite development" NARROW [GOC:mah] synonym: "regulation of neurite formation" NARROW [GOC:mah] synonym: "regulation of neurite growth" NARROW [GOC:mah] is_a: GO:0120035 ! regulation of plasma membrane bounded cell projection organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0031175 ! neuron projection development relationship: regulates GO:0031175 ! neuron projection development created_by: tb creation_date: 2009-06-01T10:44:45Z [Term] id: GO:0010976 name: positive regulation of neuron projection development namespace: biological_process def: "Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." [GOC:dph, GOC:tb] synonym: "positive regulation of neurite biosynthesis" NARROW [GOC:mah] synonym: "positive regulation of neurite development" NARROW [GOC:mah] synonym: "positive regulation of neurite formation" NARROW [GOC:mah] synonym: "positive regulation of neurite growth" NARROW [GOC:mah] is_a: GO:0010975 ! regulation of neuron projection development is_a: GO:0031346 ! positive regulation of cell projection organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0031175 ! neuron projection development relationship: positively_regulates GO:0031175 ! neuron projection development created_by: tb creation_date: 2009-06-01T10:46:44Z [Term] id: GO:0010977 name: negative regulation of neuron projection development namespace: biological_process def: "Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." [GOC:dph, GOC:tb] synonym: "growth cone collapse" RELATED [GOC:pr] synonym: "negative regulation of neurite biosynthesis" NARROW [GOC:mah] synonym: "negative regulation of neurite development" NARROW [GOC:mah] synonym: "negative regulation of neurite formation" NARROW [GOC:mah] synonym: "negative regulation of neurite growth" NARROW [GOC:mah] is_a: GO:0010975 ! regulation of neuron projection development is_a: GO:0031345 ! negative regulation of cell projection organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0031175 ! neuron projection development relationship: negatively_regulates GO:0031175 ! neuron projection development created_by: tb creation_date: 2009-06-01T10:47:42Z [Term] id: GO:0012501 name: programmed cell death namespace: biological_process alt_id: GO:0016244 def: "A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell." [GOC:lr, GOC:mtg_apoptosis] comment: Note that this term should be used to annotate gene products in the organism undergoing the programmed cell death. To annotate genes in another organism whose products modulate programmed cell death in a host organism, consider the term 'modulation by symbiont of host programmed cell death ; GO:0052040'. Also, note that 'programmed cell death ; GO:0012501' should be used to refer to instances of caspase-independent cell death mechanisms, in the absence of further indications on the process taking place. At present, caspase-independent cell death is not yet represented in GO due to the lack of consensus and in-depth research on the topic. 'programmed cell death ; GO:0012501' may also be used to annotate gene products in taxa where apoptosis as defined in GO:0006915 does not occur, such as plants. You may also consider these specific children: GO:0097468 'programmed cell death in response to reactive oxygen species' (with descendants GO:0010421 'hydrogen peroxide-mediated programmed cell death' and GO:0010343 'singlet oxygen-mediated programmed cell death'), and GO:0009626 'plant-type hypersensitive response' and its children. subset: goslim_agr subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_mouse subset: goslim_plant subset: goslim_prokaryote synonym: "caspase-independent apoptosis" RELATED [] synonym: "caspase-independent cell death" NARROW [] synonym: "non-apoptotic programmed cell death" NARROW [] synonym: "nonapoptotic programmed cell death" NARROW [] synonym: "PCD" RELATED [] synonym: "RCD" RELATED [] synonym: "regulated cell death" BROAD [] xref: Wikipedia:Programmed_cell_death is_a: GO:0008219 ! cell death intersection_of: GO:0008219 ! cell death intersection_of: starts_with GO:0007165 ! signal transduction relationship: starts_with GO:0007165 ! signal transduction property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24835" xsd:anyURI [Term] id: GO:0012505 name: endomembrane system namespace: cellular_component def: "A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles." [GOC:lh] subset: goslim_candida subset: goslim_flybase_ribbon subset: goslim_yeast xref: Wikipedia:Endomembrane_system is_a: GO:0110165 ! cellular anatomical entity relationship: has_part GO:0005773 ! vacuole relationship: has_part GO:0005886 ! plasma membrane relationship: part_of CL:0000000 ! cell [Term] id: GO:0012506 name: vesicle membrane namespace: cellular_component def: "The lipid bilayer surrounding any membrane-bounded vesicle in the cell." [GOC:mah, GOC:vesicle] xref: NIF_Subcellular:sao1153182838 is_a: GO:0031090 ! organelle membrane intersection_of: GO:0016020 ! membrane intersection_of: part_of GO:0031982 ! vesicle relationship: part_of GO:0031982 ! vesicle [Term] id: GO:0014009 name: glial cell proliferation namespace: biological_process def: "The multiplication or reproduction of glial cells by cell division, resulting in the expansion of their population. Glial cells exist throughout the nervous system, and include Schwann cells, astrocytes, and oligodendrocytes among others." [GOC:ef, ISBN:0878932585] synonym: "glia proliferation" EXACT [] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000125 ! glial cell relationship: acts_on_population_of CL:0000125 ! glial cell relationship: part_of GO:0042063 ! gliogenesis [Term] id: GO:0014013 name: regulation of gliogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of gliogenesis, the formation of mature glia." [GOC:ef] is_a: GO:0050767 ! regulation of neurogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0042063 ! gliogenesis relationship: regulates GO:0042063 ! gliogenesis [Term] id: GO:0014014 name: negative regulation of gliogenesis namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of gliogenesis, the formation of mature glia." [GOC:ef] synonym: "down regulation of gliogenesis" EXACT [] synonym: "down-regulation of gliogenesis" EXACT [] synonym: "downregulation of gliogenesis" EXACT [] synonym: "inhibition of gliogenesis" NARROW [] is_a: GO:0014013 ! regulation of gliogenesis is_a: GO:0050768 ! negative regulation of neurogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0042063 ! gliogenesis relationship: negatively_regulates GO:0042063 ! gliogenesis [Term] id: GO:0014015 name: positive regulation of gliogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of gliogenesis, the formation of mature glia." [GOC:ef] synonym: "activation of gliogenesis" NARROW [] synonym: "stimulation of gliogenesis" NARROW [] synonym: "up regulation of gliogenesis" EXACT [] synonym: "up-regulation of gliogenesis" EXACT [] synonym: "upregulation of gliogenesis" EXACT [] is_a: GO:0014013 ! regulation of gliogenesis is_a: GO:0050769 ! positive regulation of neurogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0042063 ! gliogenesis relationship: positively_regulates GO:0042063 ! gliogenesis [Term] id: GO:0014016 name: neuroblast differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a neuroblast. There are at least four stages through which the pluripotent cells of epiblast or blastula become neuroblasts." [GOC:ef, ISBN:0878932585] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000031 ! neuroblast (sensu Vertebrata) relationship: part_of GO:0048699 ! generation of neurons relationship: results_in_acquisition_of_features_of CL:0000031 ! neuroblast (sensu Vertebrata) [Term] id: GO:0014019 name: neuroblast development namespace: biological_process def: "The process aimed at the progression of a neuroblast over time, from initial commitment of the cell to a specific state, to the mature neuroblast. It does not include processes where the neuroblast turns into a glial cell or a neuron." [GOC:ef, ISBN:0878932585] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000031 ! neuroblast (sensu Vertebrata) relationship: part_of GO:0014016 ! neuroblast differentiation relationship: results_in_development_of CL:0000031 ! neuroblast (sensu Vertebrata) [Term] id: GO:0014020 name: primary neural tube formation namespace: biological_process alt_id: GO:0014024 def: "The formation of the neural tube from an epithelial cell sheet (the neuroepithelium or neural plate). In primary neurulation, the cells surrounding the neural plate direct the neural plate cells to proliferate, invaginate, and pinch off from the surface to form a hollow epithelial tube. Primary neurulation is the typical mechanism of formation of the anterior neural tube." [GOC:ef, ISBN:0878932585, PMID:15327780] synonym: "neural rod cavitation" RELATED [] synonym: "primary neural tube morphogenesis" EXACT [GOC:dph] synonym: "primary neurulation" EXACT [] is_a: GO:0001838 ! embryonic epithelial tube formation relationship: part_of GO:0001841 ! neural tube formation [Term] id: GO:0014023 name: neural rod formation namespace: biological_process def: "The formation of a solid rod of neurectoderm derived from the neural keel. The neural rod is roughly circular in cross section. Neural rod formation occurs during primary neurulation in teleosts." [GOC:dh, GOC:ef] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0005068 ! neural rod relationship: in_taxon NCBITaxon:32443 {all_only="true"} ! Teleostei relationship: only_in_taxon NCBITaxon:32443 ! Teleostei relationship: part_of GO:0014020 ! primary neural tube formation relationship: results_in_formation_of_anatomical_entity UBERON:0005068 ! neural rod [Term] id: GO:0014025 name: neural keel formation namespace: biological_process def: "The formation of a thickened region of the neurectoderm that is roughly triangular in cross section. The neural keel develops from the neural plate and develops into the neural rod. Neural keel formation occurs during primary neurulation in teleosts." [GOC:dh, GOC:ef] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0007135 ! neural keel relationship: part_of GO:0014023 ! neural rod formation relationship: results_in_formation_of_anatomical_entity UBERON:0007135 ! neural keel [Term] id: GO:0014028 name: notochord formation namespace: biological_process def: "The formation of the notochord from the chordamesoderm. The notochord is composed of large cells packed within a firm connective tissue sheath and is found in all chordates at the ventral surface of the neural tube. In vertebrates, the notochord contributes to the vertebral column." [GOC:dh, GOC:ef] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0002328 ! notochord relationship: part_of GO:0007399 ! nervous system development relationship: part_of GO:0048570 ! notochord morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0002328 ! notochord [Term] id: GO:0014029 name: neural crest formation namespace: biological_process def: "The formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes." [GOC:dh, GOC:ef] is_a: GO:0001837 ! epithelial to mesenchymal transition is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0002342 ! neural crest relationship: part_of GO:0043009 ! chordate embryonic development relationship: results_in_formation_of_anatomical_entity UBERON:0002342 ! neural crest [Term] id: GO:0014031 name: mesenchymal cell development namespace: biological_process def: "The process aimed at the progression of a mesenchymal cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." [GOC:dh, GOC:ef] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0008019 ! mesenchymal cell relationship: part_of GO:0048762 ! mesenchymal cell differentiation relationship: results_in_development_of CL:0008019 ! mesenchymal cell [Term] id: GO:0014032 name: neural crest cell development namespace: biological_process def: "The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." [GOC:dh, GOC:ef] is_a: GO:0048864 ! stem cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0011012 ! neural crest cell relationship: part_of GO:0014033 ! neural crest cell differentiation relationship: results_in_development_of CL:0011012 ! neural crest cell [Term] id: GO:0014033 name: neural crest cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a neural crest cell." [GOC:dh, GOC:ef] is_a: GO:0048762 ! mesenchymal cell differentiation is_a: GO:0048863 ! stem cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000333 ! migratory neural crest cell relationship: results_in_acquisition_of_features_of CL:0000333 ! migratory neural crest cell [Term] id: GO:0014041 name: regulation of neuron maturation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of neuron maturation, the process leading to the attainment of the full functional capacity of a neuron. This process is independent of morphogenetic change." [GOC:ef] is_a: GO:0045664 ! regulation of neuron differentiation is_a: GO:1903429 ! regulation of cell maturation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0042551 ! neuron maturation relationship: regulates GO:0042551 ! neuron maturation [Term] id: GO:0014042 name: positive regulation of neuron maturation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of neuron maturation." [GOC:ef] synonym: "activation of neuron maturation" NARROW [] synonym: "stimulation of neuron maturation" NARROW [] synonym: "up regulation of neuron maturation" EXACT [] synonym: "up-regulation of neuron maturation" EXACT [] synonym: "upregulation of neuron maturation" EXACT [] is_a: GO:0014041 ! regulation of neuron maturation is_a: GO:1903431 ! positive regulation of cell maturation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0042551 ! neuron maturation relationship: positively_regulates GO:0042551 ! neuron maturation [Term] id: GO:0014043 name: negative regulation of neuron maturation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of neuron maturation." [GOC:ef] synonym: "down regulation of neuron maturation" EXACT [] synonym: "down-regulation of neuron maturation" EXACT [] synonym: "downregulation of neuron maturation" EXACT [] synonym: "inhibition of neuron maturation" NARROW [] is_a: GO:0014041 ! regulation of neuron maturation is_a: GO:1903430 ! negative regulation of cell maturation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0042551 ! neuron maturation relationship: negatively_regulates GO:0042551 ! neuron maturation [Term] id: GO:0014055 name: acetylcholine secretion, neurotransmission namespace: biological_process def: "The regulated release of acetylcholine by a cell. The acetylcholine acts as a neurotransmitter that acts in both the peripheral nervous system (PNS) and central nervous system (CNS)." [GOC:ef] is_a: GO:0007269 ! neurotransmitter secretion is_a: GO:0061526 ! acetylcholine secretion intersection_of: GO:0061526 ! acetylcholine secretion intersection_of: part_of GO:0007271 ! synaptic transmission, cholinergic relationship: part_of GO:0007271 ! synaptic transmission, cholinergic [Term] id: GO:0014056 name: regulation of acetylcholine secretion, neurotransmission namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of acetylcholine." [GOC:ef] is_a: GO:0032222 ! regulation of synaptic transmission, cholinergic is_a: GO:0046928 ! regulation of neurotransmitter secretion is_a: GO:0051952 ! regulation of amine transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0014055 ! acetylcholine secretion, neurotransmission relationship: regulates GO:0014055 ! acetylcholine secretion, neurotransmission [Term] id: GO:0014057 name: positive regulation of acetylcholine secretion, neurotransmission namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of acetylcholine." [GOC:ef] synonym: "activation of acetylcholine secretion" NARROW [] synonym: "stimulation of acetylcholine secretion" NARROW [] synonym: "up regulation of acetylcholine secretion" EXACT [] synonym: "up-regulation of acetylcholine secretion" EXACT [] synonym: "upregulation of acetylcholine secretion" EXACT [] is_a: GO:0001956 ! positive regulation of neurotransmitter secretion is_a: GO:0014056 ! regulation of acetylcholine secretion, neurotransmission is_a: GO:0032224 ! positive regulation of synaptic transmission, cholinergic is_a: GO:0051954 ! positive regulation of amine transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0014055 ! acetylcholine secretion, neurotransmission relationship: positively_regulates GO:0014055 ! acetylcholine secretion, neurotransmission [Term] id: GO:0014058 name: negative regulation of acetylcholine secretion, neurotransmission namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of acetylcholine." [GOC:ef] synonym: "down regulation of acetylcholine secretion" EXACT [] synonym: "down-regulation of acetylcholine secretion" EXACT [] synonym: "downregulation of acetylcholine secretion" EXACT [] synonym: "inhibition of acetylcholine secretion" NARROW [] is_a: GO:0014056 ! regulation of acetylcholine secretion, neurotransmission is_a: GO:0032223 ! negative regulation of synaptic transmission, cholinergic is_a: GO:0046929 ! negative regulation of neurotransmitter secretion is_a: GO:0051953 ! negative regulation of amine transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0014055 ! acetylcholine secretion, neurotransmission relationship: negatively_regulates GO:0014055 ! acetylcholine secretion, neurotransmission [Term] id: GO:0014061 name: regulation of norepinephrine secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of norepinephrine." [GOC:ef] synonym: "regulation of noradrenaline secretion" EXACT [] is_a: GO:0050433 ! regulation of catecholamine secretion intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048243 ! norepinephrine secretion relationship: regulates GO:0048243 ! norepinephrine secretion [Term] id: GO:0014062 name: regulation of serotonin secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of serotonin." [GOC:ef] synonym: "regulation of serotonin release" RELATED [GOC:tb] is_a: GO:0043269 ! regulation of monoatomic ion transport is_a: GO:1903530 ! regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001820 ! serotonin secretion relationship: regulates GO:0001820 ! serotonin secretion [Term] id: GO:0014063 name: negative regulation of serotonin secretion namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of serotonin." [GOC:ef] synonym: "down regulation of serotonin secretion" EXACT [] synonym: "down-regulation of serotonin secretion" EXACT [] synonym: "downregulation of serotonin secretion" EXACT [] synonym: "inhibition of serotonin secretion" NARROW [] synonym: "positive regulation of serotonin release" RELATED [GOC:tb] is_a: GO:0014062 ! regulation of serotonin secretion is_a: GO:0043271 ! negative regulation of monoatomic ion transport is_a: GO:1903531 ! negative regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001820 ! serotonin secretion relationship: negatively_regulates GO:0001820 ! serotonin secretion [Term] id: GO:0014064 name: positive regulation of serotonin secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of serotonin." [GOC:ef] synonym: "activation of serotonin secretion" NARROW [] synonym: "positive regulation of serotonin release" RELATED [GOC:tb] synonym: "stimulation of serotonin secretion" NARROW [] synonym: "up regulation of serotonin secretion" EXACT [] synonym: "up-regulation of serotonin secretion" EXACT [] synonym: "upregulation of serotonin secretion" EXACT [] is_a: GO:0014062 ! regulation of serotonin secretion is_a: GO:0043270 ! positive regulation of monoatomic ion transport is_a: GO:1903532 ! positive regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001820 ! serotonin secretion relationship: positively_regulates GO:0001820 ! serotonin secretion [Term] id: GO:0014070 name: response to organic cyclic compound namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus." [GOC:ef] synonym: "response to organic cyclic substance" EXACT [GOC:mah] is_a: GO:0010033 ! response to organic substance intersection_of: GO:0050896 ! response to stimulus intersection_of: has_primary_input CHEBI:33832 ! organic cyclic compound relationship: has_primary_input CHEBI:33832 ! organic cyclic compound [Term] id: GO:0014075 name: response to amine namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups." [GOC:ef] synonym: "response to amine stimulus" EXACT [GOC:dos] is_a: GO:0010243 ! response to organonitrogen compound intersection_of: GO:0050896 ! response to stimulus intersection_of: has_primary_input CHEBI:32952 ! amine relationship: has_primary_input CHEBI:32952 ! amine [Term] id: GO:0014706 name: striated muscle tissue development namespace: biological_process def: "The process whose specific outcome is the progression of a striated muscle over time, from its formation to the mature structure. Striated muscle contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. Skeletal muscle myoblasts fuse to form myotubes and eventually multinucleated muscle fibers. The fusion of cardiac cells is very rare and can only form binucleate cells." [CL:0000737, GOC:dph, GOC:mtg_muscle] is_a: GO:0060537 ! muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002036 ! striated muscle tissue relationship: results_in_development_of UBERON:0002036 ! striated muscle tissue [Term] id: GO:0014733 name: regulation of skeletal muscle adaptation namespace: biological_process def: "Any process in which skeletal muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities." [GOC:mtg_muscle] synonym: "regulation of skeletal muscle plasticity" RELATED [] is_a: GO:0043502 ! regulation of muscle adaptation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0043501 ! skeletal muscle adaptation relationship: regulates GO:0043501 ! skeletal muscle adaptation [Term] id: GO:0014734 name: skeletal muscle hypertrophy namespace: biological_process def: "The enlargement or overgrowth of all or part of an organ due to an increase in size (not length) of individual muscle fibers without cell division. In the case of skeletal muscle cells this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils." [GOC:mtg_muscle] is_a: GO:0014897 ! striated muscle hypertrophy is_a: GO:0043501 ! skeletal muscle adaptation intersection_of: GO:0014896 ! muscle hypertrophy intersection_of: occurs_in UBERON:0001134 ! skeletal muscle tissue [Term] id: GO:0014741 name: negative regulation of muscle hypertrophy namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hypertrophy." [GOC:mtg_muscle] is_a: GO:0014743 ! regulation of muscle hypertrophy is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0014896 ! muscle hypertrophy relationship: negatively_regulates GO:0014896 ! muscle hypertrophy [Term] id: GO:0014742 name: positive regulation of muscle hypertrophy namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of muscle hypertrophy." [GOC:mtg_muscle] is_a: GO:0014743 ! regulation of muscle hypertrophy is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0014896 ! muscle hypertrophy relationship: positively_regulates GO:0014896 ! muscle hypertrophy [Term] id: GO:0014743 name: regulation of muscle hypertrophy namespace: biological_process def: "Any process that modulates the frequency, rate or extent of muscle hypertrophy." [GOC:mtg_muscle] is_a: GO:0090257 ! regulation of muscle system process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0014896 ! muscle hypertrophy relationship: regulates GO:0014896 ! muscle hypertrophy [Term] id: GO:0014744 name: positive regulation of muscle adaptation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of muscle adaptation." [GOC:mtg_muscle] synonym: "positive regulation of muscle plasticity" RELATED [] is_a: GO:0043502 ! regulation of muscle adaptation is_a: GO:0048584 ! positive regulation of response to stimulus is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0043500 ! muscle adaptation relationship: positively_regulates GO:0043500 ! muscle adaptation [Term] id: GO:0014745 name: negative regulation of muscle adaptation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle adaptation." [GOC:mtg_muscle] synonym: "negative regulation of muscle plasticity" RELATED [] is_a: GO:0043502 ! regulation of muscle adaptation is_a: GO:0048585 ! negative regulation of response to stimulus is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0043500 ! muscle adaptation relationship: negatively_regulates GO:0043500 ! muscle adaptation [Term] id: GO:0014805 name: smooth muscle adaptation namespace: biological_process def: "Any process in which smooth muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities." [GOC:mtg_muscle] synonym: "smooth muscle plasticity" RELATED [] is_a: GO:0043500 ! muscle adaptation intersection_of: GO:0043500 ! muscle adaptation intersection_of: occurs_in UBERON:0001135 ! smooth muscle tissue relationship: occurs_in UBERON:0001135 ! smooth muscle tissue [Term] id: GO:0014807 name: regulation of somitogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of somitogenesis." [GOC:mtg_muscle] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001756 ! somitogenesis relationship: regulates GO:0001756 ! somitogenesis [Term] id: GO:0014812 name: muscle cell migration namespace: biological_process def: "The orderly movement of a muscle cell from one site to another, often during the development of a multicellular organism." [CL:0000187, GOC:mtg_muscle] is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000187 ! muscle cell relationship: results_in_movement_of CL:0000187 ! muscle cell [Term] id: GO:0014819 name: regulation of skeletal muscle contraction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of skeletal muscle contraction." [GOC:ef, GOC:mtg_muscle] is_a: GO:0006942 ! regulation of striated muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003009 ! skeletal muscle contraction relationship: regulates GO:0003009 ! skeletal muscle contraction [Term] id: GO:0014821 name: phasic smooth muscle contraction namespace: biological_process def: "A process in which force is generated within phasic smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the phasic smooth muscle, the muscle contraction occurs without an ordered sarcomeric structure. Phasic smooth muscle contraction occurs in a series of discrete contractions and relaxations." [GOC:mtg_muscle] is_a: GO:0006939 ! smooth muscle contraction [Term] id: GO:0014827 name: intestine smooth muscle contraction namespace: biological_process def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the intestine. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The intestine is the section of the alimentary canal from the stomach to the anal canal. It includes the large intestine and small intestine." [GOC:mtg_muscle, MA:0001539, MSH:D007422] is_a: GO:0014821 ! phasic smooth muscle contraction is_a: GO:0014831 ! gastro-intestinal system smooth muscle contraction [Term] id: GO:0014831 name: gastro-intestinal system smooth muscle contraction namespace: biological_process def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the gastro-intestinal system. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The gastro-intestinal system generally refers to the digestive structures stretching from the mouth to anus, but does not include the accessory glandular organs (liver, pancreas and biliary tract)." [GOC:mtg_muscle, MA:0001523, MSH:D041981] is_a: GO:0006939 ! smooth muscle contraction [Term] id: GO:0014832 name: urinary bladder smooth muscle contraction namespace: biological_process def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary bladder. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary bladder is a musculomembranous sac along the urinary tract." [GOC:mr, GOC:mtg_muscle, PMID:11768524, PMID:18276178, PMID:538956] is_a: GO:0014848 ! urinary tract smooth muscle contraction property_value: RO:0002161 NCBITaxon:8782 [Term] id: GO:0014848 name: urinary tract smooth muscle contraction namespace: biological_process def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary tract. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary tract consists of organs of the body that produce and discharge urine. These include the kidneys, ureters, bladder, and urethra." [GOC:ef, GOC:mtg_muscle, MA:0000325, MSH:D014551] is_a: GO:0006939 ! smooth muscle contraction [Term] id: GO:0014849 name: ureter smooth muscle contraction namespace: biological_process def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the ureter. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder." [GOC:mtg_muscle, MA:0000378] is_a: GO:0014821 ! phasic smooth muscle contraction is_a: GO:0014848 ! urinary tract smooth muscle contraction [Term] id: GO:0014852 name: regulation of skeletal muscle contraction by neural stimulation via neuromuscular junction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of skeletal muscle contraction by variation of the pattern of stimulation by nervous system." [GOC:ef, GOC:mtg_muscle] is_a: GO:0014819 ! regulation of skeletal muscle contraction [Term] id: GO:0014855 name: striated muscle cell proliferation namespace: biological_process def: "The multiplication or reproduction of striated muscle cells, resulting in the expansion of a cell population. Striated muscles contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle." [CL:0000737, GOC:ef, GOC:mtg_muscle] is_a: GO:0033002 ! muscle cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000737 ! striated muscle cell relationship: acts_on_population_of CL:0000737 ! striated muscle cell [Term] id: GO:0014856 name: skeletal muscle cell proliferation namespace: biological_process def: "The multiplication or reproduction of skeletal muscle cells, resulting in the expansion of a cell population." [CL:0000188, GOC:ef, GOC:mtg_muscle] is_a: GO:0014855 ! striated muscle cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000188 ! cell of skeletal muscle relationship: acts_on_population_of CL:0000188 ! cell of skeletal muscle [Term] id: GO:0014857 name: regulation of skeletal muscle cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of skeletal muscle cell proliferation." [CL:0000188, GOC:ef, GOC:mtg_muscle] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0014856 ! skeletal muscle cell proliferation relationship: regulates GO:0014856 ! skeletal muscle cell proliferation [Term] id: GO:0014858 name: positive regulation of skeletal muscle cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of skeletal muscle cell proliferation." [CL:0000188, GOC:ef, GOC:mtg_muscle] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0014857 ! regulation of skeletal muscle cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0014856 ! skeletal muscle cell proliferation relationship: positively_regulates GO:0014856 ! skeletal muscle cell proliferation [Term] id: GO:0014859 name: negative regulation of skeletal muscle cell proliferation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle cell proliferation." [CL:0000188, GOC:ef, GOC:mtg_muscle] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0014857 ! regulation of skeletal muscle cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0014856 ! skeletal muscle cell proliferation relationship: negatively_regulates GO:0014856 ! skeletal muscle cell proliferation [Term] id: GO:0014860 name: neurotransmitter secretion involved in regulation of skeletal muscle contraction namespace: biological_process def: "The regulated release of neurotransmitter into the synaptic cleft involved in skeletal muscle contraction. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin." [GOC:dph, GOC:mtg_muscle, GOC:tb] synonym: "neurotransmitter secretion involved in control of skeletal muscle contraction" EXACT [GOC:dph, GOC:tb] is_a: GO:0007269 ! neurotransmitter secretion intersection_of: GO:0007269 ! neurotransmitter secretion intersection_of: part_of GO:0014819 ! regulation of skeletal muscle contraction relationship: part_of GO:0014852 ! regulation of skeletal muscle contraction by neural stimulation via neuromuscular junction [Term] id: GO:0014861 name: regulation of skeletal muscle contraction via regulation of action potential namespace: biological_process def: "Any process that modulates the frequency, rate or extent of skeletal muscle contraction by depolarization of muscle membrane and ionic fluxes." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:mtg_muscle] synonym: "regulation of skeletal muscle contraction via membrane action potential" RELATED [] is_a: GO:0014819 ! regulation of skeletal muscle contraction is_a: GO:0098900 ! regulation of action potential intersection_of: GO:0050789 ! regulation of biological process intersection_of: regulates GO:0100001 ! regulation of skeletal muscle contraction by action potential relationship: regulates GO:0100001 ! regulation of skeletal muscle contraction by action potential [Term] id: GO:0014866 name: skeletal myofibril assembly namespace: biological_process def: "The process whose specific outcome is the progression of the skeletal myofibril over time, from its formation to the mature structure. A skeletal myofibril is a myofibril specific to skeletal muscle cells." [GOC:ef, GOC:mtg_muscle] is_a: GO:0030239 ! myofibril assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0098723 ! skeletal muscle myofibril relationship: results_in_assembly_of GO:0098723 ! skeletal muscle myofibril [Term] id: GO:0014872 name: myoblast division namespace: biological_process def: "The process resulting in the physical partitioning and separation of a myoblast into daughter cells. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:ef, GOC:mtg_muscle] is_a: GO:0051301 ! cell division intersection_of: GO:0051301 ! cell division intersection_of: has_primary_input CL:0000056 ! myoblast relationship: has_primary_input CL:0000056 ! myoblast [Term] id: GO:0014874 name: response to stimulus involved in regulation of muscle adaptation namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. This occurs as part of the regulation of muscle adaptation." [GOC:ef, GOC:mtg_muscle] synonym: "response to stimulus involved in regulation of muscle plasticity" RELATED [] is_a: GO:0050896 ! response to stimulus intersection_of: GO:0050896 ! response to stimulus intersection_of: part_of GO:0043502 ! regulation of muscle adaptation relationship: part_of GO:0043502 ! regulation of muscle adaptation [Term] id: GO:0014878 name: response to electrical stimulus involved in regulation of muscle adaptation namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus. This process occurs as part of the regulation of muscle adaptation." [GOC:ef, GOC:mtg_muscle] synonym: "response to electrical stimulus involved in regulation of muscle plasticity" RELATED [] is_a: GO:0014874 ! response to stimulus involved in regulation of muscle adaptation is_a: GO:0051602 ! response to electrical stimulus intersection_of: GO:0051602 ! response to electrical stimulus intersection_of: part_of GO:0043502 ! regulation of muscle adaptation [Term] id: GO:0014879 name: detection of electrical stimulus involved in regulation of muscle adaptation namespace: biological_process def: "The series of events by which an electrical stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation." [GOC:ef, GOC:mtg_muscle] is_a: GO:0014878 ! response to electrical stimulus involved in regulation of muscle adaptation is_a: GO:0050981 ! detection of electrical stimulus intersection_of: GO:0050981 ! detection of electrical stimulus intersection_of: part_of GO:0043502 ! regulation of muscle adaptation [Term] id: GO:0014887 name: cardiac muscle adaptation namespace: biological_process def: "The process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors." [GOC:mtg_muscle] synonym: "cardiac muscle plasticity" RELATED [] is_a: GO:0014888 ! striated muscle adaptation intersection_of: GO:0043500 ! muscle adaptation intersection_of: occurs_in UBERON:0001133 ! cardiac muscle tissue relationship: occurs_in UBERON:0001133 ! cardiac muscle tissue [Term] id: GO:0014888 name: striated muscle adaptation namespace: biological_process def: "Any process in which striated muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities." [GOC:mtg_muscle] synonym: "striated muscle plasticity" RELATED [] is_a: GO:0043500 ! muscle adaptation intersection_of: GO:0043500 ! muscle adaptation intersection_of: occurs_in UBERON:0002036 ! striated muscle tissue relationship: occurs_in UBERON:0002036 ! striated muscle tissue [Term] id: GO:0014895 name: smooth muscle hypertrophy namespace: biological_process def: "The enlargement or overgrowth of all or part of an organ due to an increase in size of its smooth muscle cells without cell division. Physiological hypertrophy is a normal process during development, and can also occur in mature structures on demand. In the uterus, smooth muscle cells undergo hypertrophy during pregnancy." [GOC:mtg_muscle] is_a: GO:0014805 ! smooth muscle adaptation is_a: GO:0014896 ! muscle hypertrophy intersection_of: GO:0014896 ! muscle hypertrophy intersection_of: occurs_in UBERON:0001135 ! smooth muscle tissue [Term] id: GO:0014896 name: muscle hypertrophy namespace: biological_process def: "The muscle system process that results in enlargement or overgrowth of all or part of a muscle organ due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development (it stops in cardiac muscle after adolescence) and can also be brought on in response to demand. In athletes cardiac and skeletal muscles undergo hypertrophy stimulated by increasing muscle activity on exercise. Smooth muscle cells in the uterus undergo hypertrophy during pregnancy." [GOC:mtg_muscle] xref: Wikipedia:Muscle_hypertrophy is_a: GO:0003012 ! muscle system process relationship: occurs_in UBERON:0002385 ! muscle tissue [Term] id: GO:0014897 name: striated muscle hypertrophy namespace: biological_process def: "The enlargement or overgrowth of all or part of an organ due to an increase in size of muscle cells without cell division. In the case of striated muscle, this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils." [GOC:mtg_muscle] is_a: GO:0014896 ! muscle hypertrophy intersection_of: GO:0014896 ! muscle hypertrophy intersection_of: has_primary_input UBERON:0002036 ! striated muscle tissue relationship: has_primary_input UBERON:0002036 ! striated muscle tissue [Term] id: GO:0014902 name: myotube differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." [GOC:mtg_muscle] is_a: GO:0051146 ! striated muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0002372 ! myotube relationship: results_in_acquisition_of_features_of CL:0002372 ! myotube [Term] id: GO:0014904 name: myotube cell development namespace: biological_process def: "The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." [GOC:mtg_muscle] is_a: GO:0055002 ! striated muscle cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0002372 ! myotube relationship: part_of GO:0014902 ! myotube differentiation relationship: results_in_development_of CL:0002372 ! myotube [Term] id: GO:0014909 name: smooth muscle cell migration namespace: biological_process def: "The orderly movement of a smooth muscle cell from one site to another, often during the development of a multicellular organism." [CL:0000192, GOC:mtg_muscle] is_a: GO:0014812 ! muscle cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000192 ! smooth muscle cell relationship: results_in_movement_of CL:0000192 ! smooth muscle cell [Term] id: GO:0014910 name: regulation of smooth muscle cell migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of smooth muscle cell migration." [CL:0000192, GOC:mtg_muscle] is_a: GO:0030334 ! regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0014909 ! smooth muscle cell migration relationship: regulates GO:0014909 ! smooth muscle cell migration [Term] id: GO:0014911 name: positive regulation of smooth muscle cell migration namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of smooth muscle cell migration." [CL:0000192, GOC:mtg_muscle] is_a: GO:0014910 ! regulation of smooth muscle cell migration is_a: GO:0030335 ! positive regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0014909 ! smooth muscle cell migration relationship: positively_regulates GO:0014909 ! smooth muscle cell migration [Term] id: GO:0014912 name: negative regulation of smooth muscle cell migration namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell migration." [CL:0000192, GOC:mtg_muscle] is_a: GO:0014910 ! regulation of smooth muscle cell migration is_a: GO:0030336 ! negative regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0014909 ! smooth muscle cell migration relationship: negatively_regulates GO:0014909 ! smooth muscle cell migration [Term] id: GO:0015031 name: protein transport namespace: biological_process alt_id: GO:0015831 def: "The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] subset: goslim_chembl subset: goslim_pir subset: goslim_yeast synonym: "enzyme transport" NARROW [] is_a: GO:0008104 ! protein localization is_a: GO:0045184 ! establishment of protein localization is_a: GO:0071702 ! organic substance transport is_a: GO:0071705 ! nitrogen compound transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input PR:000000001 ! protein [Term] id: GO:0015075 name: monoatomic ion transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of an ion from one side of a membrane to the other." [GOC:dgf, GOC:mtg_transport, ISBN:0815340729] synonym: "ion transmembrane transporter activity" BROAD [] synonym: "ion transporter activity" EXACT [] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:24867 ! monoatomic ion relationship: has_primary_input CHEBI:24867 ! monoatomic ion relationship: part_of GO:0034220 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! monoatomic ion transmembrane transport property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24479" xsd:anyURI [Term] id: GO:0015081 name: sodium ion transmembrane transporter activity namespace: molecular_function alt_id: GO:0022816 def: "Enables the transfer of sodium ions (Na+) from one side of a membrane to the other." [GOC:ai, GOC:BHF, RHEA:34963] synonym: "sodium transporter activity" EXACT [] xref: RHEA:34963 is_a: GO:0046873 ! metal ion transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:29101 ! sodium(1+) relationship: has_participant CHEBI:29101 ! sodium(1+) relationship: has_primary_input CHEBI:29101 ! sodium(1+) relationship: part_of GO:0035725 ! sodium ion transmembrane transport property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24076" xsd:anyURI [Term] id: GO:0015101 name: organic cation transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of organic cations from one side of a membrane to the other. Organic cations are atoms or small molecules with a positive charge that contain carbon in covalent linkage." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] xref: Reactome:R-HSA-2161500 "abacavir [extracellular] => abacavir [cytosol]" xref: Reactome:R-HSA-549129 "OCT1 transports organic cations into hepatic cells" xref: Reactome:R-HSA-549279 "OCT2 mediates tubular uptake of organic cations in the kidney" xref: Reactome:R-HSA-549304 "OCT3 mediates renal clearance of organic cations" xref: Reactome:R-HSA-549322 "OCT1 transports organic cations out of hepatic cells" xref: Reactome:R-HSA-561054 "OCT2 mediates tubular secretion of organic cations in the kidney" xref: Reactome:R-HSA-561072 "OCT3 mediates renal uptake of organic cations" xref: Reactome:R-HSA-9794270 "SLCO1A2 transports Cipro(1+) into the cytosol" xref: Reactome:R-HSA-9794523 "SLC22A1 transports Cipro into renal cell" xref: Reactome:R-HSA-9795207 "SLC22A1 transports Cipro into hepatic cell" is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:25697 ! organic cation relationship: has_primary_input CHEBI:25697 ! organic cation relationship: part_of GO:0015695 ! organic cation transport [Term] id: GO:0015103 name: inorganic anion transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of inorganic anions from one side of a membrane to the other. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage." [GOC:ai] is_a: GO:0015318 ! inorganic molecular entity transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:24834 ! inorganic anion relationship: has_primary_input CHEBI:24834 ! inorganic anion relationship: part_of GO:0015698 ! inorganic anion transport [Term] id: GO:0015106 name: bicarbonate transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of bicarbonate from one side of a membrane to the other. Bicarbonate is the hydrogencarbonate ion, HCO3-." [GOC:ai] xref: Reactome:R-HSA-2752067 "BESTs transport cytosolic HCO3- to extracellular region" xref: RHEA:28695 is_a: GO:0008514 ! organic anion transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:17544 ! hydrogencarbonate relationship: has_participant CHEBI:17544 ! hydrogencarbonate relationship: has_primary_input CHEBI:17544 ! hydrogencarbonate relationship: part_of GO:0015701 ! bicarbonate transport [Term] id: GO:0015114 name: phosphate ion transmembrane transporter activity namespace: molecular_function alt_id: GO:1901677 def: "Enables the transfer of phosphate (PO4 3-) ions from one side of a membrane to the other." [GOC:ai] synonym: "phosphate transmembrane transporter activity" RELATED [GOC:vw] xref: RHEA:32823 is_a: GO:0015103 ! inorganic anion transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:35780 ! phosphate ion relationship: has_participant CHEBI:43474 ! hydrogenphosphate relationship: has_primary_input CHEBI:35780 ! phosphate ion relationship: part_of GO:0035435 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! phosphate ion transmembrane transport created_by: pr creation_date: 2012-11-22T15:43:10Z [Term] id: GO:0015116 name: sulfate transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of sulfate ions, SO4(2-), from one side of a membrane to the other." [GOC:ai] synonym: "sulfate permease activity" RELATED [] synonym: "sulphate transporter activity" EXACT [] xref: Reactome:R-HSA-3560789 "Defective SLC26A2 does not cotransport extracellular SO4(2-), H+ to cytosol" xref: Reactome:R-HSA-427555 "SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol" xref: Reactome:R-HSA-8875871 "SLC26A11 transports SO4(2-) from extracellular region to cytosol" xref: RHEA:34983 is_a: GO:0015103 ! inorganic anion transmembrane transporter activity is_a: GO:1901682 ! sulfur compound transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:16189 ! sulfate relationship: has_participant CHEBI:16189 ! sulfate relationship: has_primary_input CHEBI:16189 ! sulfate relationship: part_of GO:1902358 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! sulfate transmembrane transport [Term] id: GO:0015123 name: acetate transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of acetate from one side of a membrane to the other. Acetate is the 2-carbon carboxylic acid ethanoic acid." [GOC:ai] is_a: GO:0046943 ! carboxylic acid transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:30089 ! acetate relationship: has_primary_input CHEBI:30089 ! acetate relationship: part_of GO:0035433 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! acetate transmembrane transport [Term] id: GO:0015125 name: bile acid transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of bile acid from one side of a membrane to the other. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine." [GOC:ai] xref: Reactome:R-HSA-194079 "SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol" xref: Reactome:R-HSA-194083 "SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol" xref: Reactome:R-HSA-194130 "Transport (influx) of bile salts and acids by OATP-A" xref: Reactome:R-HSA-5661184 "Defective SLCO1B1 does not transport BIL from extracellular region (blood) to cytosol (hepatocyte)" xref: Reactome:R-HSA-5661198 "Defective SLCO1B3 does not transport BIL from extracellular region (blood) to cytosol (hepatocyte)" xref: Reactome:R-HSA-9733964 "SLC51A:SLC51B transports bile salts from cytosol to extracellular region" is_a: GO:0005319 ! lipid transporter activity is_a: GO:0008028 ! monocarboxylic acid transmembrane transporter activity is_a: GO:1901618 ! organic hydroxy compound transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:3098 ! bile acid relationship: has_primary_input CHEBI:3098 ! bile acid relationship: part_of GO:0015721 ! bile acid and bile salt transport [Term] id: GO:0015127 name: bilirubin transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of bilirubin from one side of a membrane to the other. Bilirubin is a linear tetrapyrrole produced in the reticuloendothelial system from biliverdin and transported to the liver as a complex with serum albumin. In the liver, bilirubin is converted to bilirubin bisglucuronide, which is excreted in the bile." [GOC:ai, ISBN:0198547684] xref: Reactome:R-HSA-5679031 "Defective ABCC2 does not transport BMG,BDG from cytosol to extracellular region" xref: Reactome:R-HSA-5679041 "ABCC2 transports BMG,BDG from cytosol to extracellular region" xref: Reactome:R-HSA-9661417 "ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region" is_a: GO:0046943 ! carboxylic acid transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:57977 ! bilirubin(2-) relationship: has_primary_input CHEBI:57977 ! bilirubin(2-) relationship: part_of GO:0015723 ! bilirubin transport [Term] id: GO:0015144 name: carbohydrate transmembrane transporter activity namespace: molecular_function alt_id: GO:1901476 def: "Enables the transfer of carbohydrate from one side of a membrane to the other." [GOC:jl, GOC:mtg_transport, ISBN:0815340729] synonym: "carbohydrate transporter activity" RELATED [] synonym: "sugar transporter" NARROW [] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:16646 ! carbohydrate relationship: has_primary_input CHEBI:16646 ! carbohydrate relationship: part_of GO:0034219 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! carbohydrate transmembrane transport [Term] id: GO:0015145 name: monosaccharide transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of a monosaccharide from one side of a membrane to the other." [GOC:jl, GOC:mtg_transport, ISBN:0815340729] is_a: GO:0051119 ! sugar transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:35381 ! monosaccharide relationship: has_primary_input CHEBI:35381 ! monosaccharide relationship: part_of GO:0015749 ! monosaccharide transmembrane transport [Term] id: GO:0015149 name: hexose transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of a hexose sugar, a monosaccharide with 6 carbon atoms, from one side of a membrane to the other." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] xref: Reactome:R-HSA-189242 "SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region" xref: Reactome:R-HSA-5638222 "Defective SLC2A2 does not transport Fru, Gal, Glc from cytosol to extracellular region" is_a: GO:0015145 ! monosaccharide transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:18133 ! hexose relationship: has_primary_input CHEBI:18133 ! hexose relationship: part_of GO:0008645 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! hexose transmembrane transport [Term] id: GO:0015159 name: polysaccharide transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of polysaccharides from one side of a membrane to the other. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] is_a: GO:0015144 ! carbohydrate transmembrane transporter activity is_a: GO:0022884 ! macromolecule transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:18154 ! polysaccharide relationship: has_primary_input CHEBI:18154 ! polysaccharide relationship: part_of GO:0015774 ! polysaccharide transport [Term] id: GO:0015171 name: amino acid transmembrane transporter activity namespace: molecular_function alt_id: GO:0015359 def: "Enables the transfer of amino acids from one side of a membrane to the other. Amino acids are organic molecules that contain an amino group and a carboxyl group." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] synonym: "amino acid permease activity" EXACT [] synonym: "amino acid transporter activity" BROAD [] synonym: "amino acid/choline transmembrane transporter activity" NARROW [] synonym: "general amino acid permease activity" RELATED [] synonym: "hydroxy/aromatic amino acid permease activity" RELATED [] xref: Reactome:R-HSA-210439 "glutamate uptake by astrocytes" xref: Reactome:R-HSA-212642 "L-Glutamine transport into neurons" xref: Reactome:R-HSA-351963 "SLC6A18 transports Gly from extracellular region to cytosol" xref: Reactome:R-HSA-351987 "SLC6A6-mediated uptake of taurine and beta-alanine" xref: Reactome:R-HSA-352029 "SLC6A12 (BGT-1)-mediated uptake of GABA and betaine" xref: Reactome:R-HSA-352052 "SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol" xref: Reactome:R-HSA-352059 "SLC6A15-mediated amino acid uptake" xref: Reactome:R-HSA-352103 "SLC43A1 (LAT3)-mediated uptake of large neutral amino acids" xref: Reactome:R-HSA-352107 "SLC43A2 (LAT4)-mediated uptake of large neutral amino acids" xref: Reactome:R-HSA-352108 "SLC38A2 (ATA2)-mediated uptake of neutral amino acids" xref: Reactome:R-HSA-352119 "SLC38A1 (ATA1)-mediated uptake of neutral amino acids" xref: Reactome:R-HSA-352136 "SLC38A4 (ATA3)-mediated uptake of arginine and lysine" xref: Reactome:R-HSA-352158 "SLC16A10-mediated uptake of aromatic amino acids" xref: Reactome:R-HSA-352174 "SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine" xref: Reactome:R-HSA-352182 "SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine" xref: Reactome:R-HSA-352191 "SLC7A8-mediated uptake of neutral amino acids" xref: Reactome:R-HSA-352232 "SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol" xref: Reactome:R-HSA-352347 "SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine" xref: Reactome:R-HSA-352354 "SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine" xref: Reactome:R-HSA-352364 "SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine" xref: Reactome:R-HSA-352371 "SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine" xref: Reactome:R-HSA-352379 "SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane" xref: Reactome:R-HSA-352385 "SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane" xref: Reactome:R-HSA-375405 "SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol" xref: Reactome:R-HSA-375417 "SLC36A1-mediated uptake of glycine, proline, and alanine" xref: Reactome:R-HSA-375473 "SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol" xref: Reactome:R-HSA-375487 "SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol" xref: Reactome:R-HSA-375768 "SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids" xref: Reactome:R-HSA-375770 "SLC7A3 (CAT-3)-mediated uptake of cationic amino acids" xref: Reactome:R-HSA-375776 "SLC7A1 (CAT-1)-mediated uptake of cationic amino acids" xref: Reactome:R-HSA-375790 "SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids" xref: Reactome:R-HSA-376200 "SLC7A10-mediated uptake of small neutral amino acids" xref: Reactome:R-HSA-378513 "SLC7A11-mediated exchange of extracellular cysteine and cytosolic glutamate" xref: Reactome:R-HSA-379415 "SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane" xref: Reactome:R-HSA-379426 "SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine" xref: Reactome:R-HSA-379432 "SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu" xref: Reactome:R-HSA-5653850 "Defective SLC36A2 does not cotransport Gly, L-Pro with H+ from extracellular region to cytosol" xref: Reactome:R-HSA-5655702 "Defective SLC3A1 (in SLC7A9:SLC3A1) does not exchange L-Arg, CySS-, L-Lys for L-Leu" xref: Reactome:R-HSA-5659674 "Variant SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol" xref: Reactome:R-HSA-5659734 "Defective SLC6A19 does not cotransport neutral amino acids, Na+ from extracellular region to cytosol" xref: Reactome:R-HSA-5659755 "Defective SLC6A18 does not transport Gly from extracellular region to cytosol" xref: Reactome:R-HSA-5660694 "Variant SLC6A20 does not cotransport L-Pro, Na+ from extracellulare region to cytosol" xref: Reactome:R-HSA-5660890 "Defective SLC7A9 (in SLC7A9:SLC3A1) does not exchange L-Arg, CySS-, L-Lys for L-Leu" xref: Reactome:R-HSA-5660910 "Defective SLC7A7 does not exchange L-Arg for L-Leu, Na+ across the plasma membrane" xref: Reactome:R-HSA-888592 "Loading of GABA into clathrin sculpted GABA transport vesicle lumen" xref: Reactome:R-HSA-8952726 "SLC38A9 transports L-Arg from lysosomal lumen to cytosol" is_a: GO:0005342 ! organic acid transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:33709 ! amino acid relationship: has_primary_input CHEBI:33709 ! amino acid relationship: part_of GO:0003333 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! amino acid transmembrane transport [Term] id: GO:0015205 name: nucleobase transmembrane transporter activity namespace: molecular_function alt_id: GO:0015392 def: "Enables the transfer of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acidfrom one side of a membrane to the other." [ISBN:0198506732] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:18282 ! nucleobase relationship: has_primary_input CHEBI:18282 ! nucleobase relationship: part_of GO:0015851 ! nucleobase transport [Term] id: GO:0015318 name: inorganic molecular entity transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of an inorganic molecular entity from the outside of a cell to the inside of the cell across a membrane. An inorganic molecular entity is a molecular entity that contains no carbon." [GOC:mtg_transport, ISBN:0815340729] subset: gocheck_do_not_annotate synonym: "inorganic solute uptake transmembrane transporter activity" EXACT [] synonym: "inorganic uptake permease activity" EXACT [] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:24835 ! inorganic molecular entity relationship: has_primary_input CHEBI:24835 ! inorganic molecular entity property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/14372" xsd:anyURI [Term] id: GO:0015629 name: actin cytoskeleton namespace: cellular_component def: "The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes." [GOC:jl, ISBN:0395825172, ISBN:0815316194] is_a: GO:0005856 ! cytoskeleton [Term] id: GO:0015630 name: microtubule cytoskeleton namespace: cellular_component def: "The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins." [GOC:jl, ISBN:0395825172] is_a: GO:0005856 ! cytoskeleton [Term] id: GO:0015669 name: gas transport namespace: biological_process def: "The directed movement of substances that are gaseous in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] subset: goslim_pir is_a: GO:0006810 ! transport [Term] id: GO:0015671 name: oxygen transport namespace: biological_process def: "The directed movement of oxygen (O2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] is_a: GO:0015669 ! gas transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:15379 ! dioxygen relationship: has_primary_input CHEBI:15379 ! dioxygen [Term] id: GO:0015695 name: organic cation transport namespace: biological_process def: "The directed movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic cations are atoms or small molecules with a positive charge which contain carbon in covalent linkage." [GOC:ai] is_a: GO:0071702 ! organic substance transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:25697 ! organic cation relationship: has_primary_input CHEBI:25697 ! organic cation [Term] id: GO:0015698 name: inorganic anion transport namespace: biological_process def: "The directed movement of inorganic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage." [GOC:krc] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:24834 ! inorganic anion relationship: has_primary_input CHEBI:24834 ! inorganic anion [Term] id: GO:0015701 name: bicarbonate transport namespace: biological_process def: "The directed movement of bicarbonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] is_a: GO:0015711 ! organic anion transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:17544 ! hydrogencarbonate relationship: has_primary_input CHEBI:17544 ! hydrogencarbonate [Term] id: GO:0015711 name: organic anion transport namespace: biological_process def: "The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage." [GOC:ai, GOC:krc] is_a: GO:0071702 ! organic substance transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:25696 ! organic anion relationship: has_primary_input CHEBI:25696 ! organic anion [Term] id: GO:0015718 name: monocarboxylic acid transport namespace: biological_process def: "The directed movement of monocarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] is_a: GO:0046942 ! carboxylic acid transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:35757 ! monocarboxylic acid anion relationship: has_primary_input CHEBI:35757 ! monocarboxylic acid anion [Term] id: GO:0015721 name: bile acid and bile salt transport namespace: biological_process def: "The directed movement of bile acid and bile salts into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:krc, PMID:12663868, PMID:14699511] synonym: "bile acid transport" NARROW [] synonym: "bile salt transport" NARROW [] is_a: GO:0006869 ! lipid transport is_a: GO:0015718 ! monocarboxylic acid transport is_a: GO:0015849 ! organic acid transport is_a: GO:0015850 ! organic hydroxy compound transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:3098 ! bile acid relationship: has_primary_input CHEBI:3098 ! bile acid [Term] id: GO:0015723 name: bilirubin transport namespace: biological_process def: "The directed movement of bilirubin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] is_a: GO:0006835 ! dicarboxylic acid transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:57977 ! bilirubin(2-) relationship: has_primary_input CHEBI:57977 ! bilirubin(2-) [Term] id: GO:0015749 name: monosaccharide transmembrane transport namespace: biological_process alt_id: GO:1905950 def: "The process in which a monosaccharide is transported across a lipid bilayer, from one side of a membrane to the other. Monosaccharides are the simplest carbohydrates; they are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides." [GO_REF:0000069, GOC:TermGenie, GOC:vw] synonym: "monosaccharide transport" RELATED [] is_a: GO:0034219 ! carbohydrate transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:35381 ! monosaccharide intersection_of: results_in_transport_across GO:0016020 ! membrane relationship: has_primary_input CHEBI:35381 ! monosaccharide created_by: vw creation_date: 2017-02-19T10:41:27Z [Term] id: GO:0015774 name: polysaccharide transport namespace: biological_process def: "The directed movement of polysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." [GOC:ai] is_a: GO:0008643 ! carbohydrate transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:18154 ! polysaccharide relationship: has_primary_input CHEBI:18154 ! polysaccharide relationship: part_of GO:0033037 ! polysaccharide localization [Term] id: GO:0015833 name: peptide transport namespace: biological_process def: "The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] subset: goslim_pir is_a: GO:0042886 ! amide transport is_a: GO:0071702 ! organic substance transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:16670 ! peptide relationship: has_primary_input CHEBI:16670 ! peptide [Term] id: GO:0015837 name: amine transport namespace: biological_process def: "The directed movement of amines, including polyamines, organic compounds containing one or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai, ISBN:0198506732] subset: goslim_pir synonym: "amine/polyamine transport" RELATED [] is_a: GO:0071702 ! organic substance transport is_a: GO:0071705 ! nitrogen compound transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:32952 ! amine relationship: has_primary_input CHEBI:32952 ! amine [Term] id: GO:0015844 name: monoamine transport namespace: biological_process alt_id: GO:0015873 def: "The directed movement of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] is_a: GO:0071702 ! organic substance transport is_a: GO:0071705 ! nitrogen compound transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:63534 ! monoamine relationship: has_primary_input CHEBI:63534 ! monoamine [Term] id: GO:0015849 name: organic acid transport namespace: biological_process def: "The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [ISBN:0198506732] subset: goslim_pir is_a: GO:0071702 ! organic substance transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:64709 ! organic acid relationship: has_primary_input CHEBI:64709 ! organic acid [Term] id: GO:0015850 name: organic hydroxy compound transport namespace: biological_process def: "The directed movement of an organic hydroxy compound (organic alcohol) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. An organic hydroxy compound is an organic compound having at least one hydroxy group attached to a carbon atom." [GOC:ai] synonym: "organic alcohol transport" EXACT [] is_a: GO:0071702 ! organic substance transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:33822 ! organic hydroxy compound relationship: has_primary_input CHEBI:33822 ! organic hydroxy compound [Term] id: GO:0015851 name: nucleobase transport namespace: biological_process def: "The directed movement of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [ISBN:0198506732] synonym: "nucleobase transmembrane transport" EXACT [GOC:mah] is_a: GO:0071702 ! organic substance transport is_a: GO:0071705 ! nitrogen compound transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:18282 ! nucleobase relationship: has_primary_input CHEBI:18282 ! nucleobase [Term] id: GO:0015869 name: protein-DNA complex transport namespace: biological_process def: "The directed movement of protein-DNA complexes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "DNA-protein complex transport" EXACT [GOC:mah] is_a: GO:0006886 ! intracellular protein transport is_a: GO:0015931 ! nucleobase-containing compound transport is_a: GO:0031503 ! protein-containing complex localization intersection_of: GO:0006810 ! transport intersection_of: has_primary_input GO:0032993 ! protein-DNA complex relationship: has_primary_input GO:0032993 ! protein-DNA complex [Term] id: GO:0015870 name: acetylcholine transport namespace: biological_process def: "The directed movement of acetylcholine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions." [GOC:ai] is_a: GO:0015695 ! organic cation transport is_a: GO:0071705 ! nitrogen compound transport is_a: GO:1901374 ! acetate ester transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:15355 ! acetylcholine relationship: has_primary_input CHEBI:15355 ! acetylcholine [Term] id: GO:0015874 name: norepinephrine transport namespace: biological_process def: "The directed movement of norepinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine." [GOC:ai, ISBN:0198506732] synonym: "levarterenol transport" EXACT [] synonym: "noradrenaline transport" EXACT [] is_a: GO:0015695 ! organic cation transport is_a: GO:0051937 ! catecholamine transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:72587 ! (R)-noradrenaline(1+) relationship: has_primary_input CHEBI:72587 ! (R)-noradrenaline(1+) [Term] id: GO:0015931 name: nucleobase-containing compound transport namespace: biological_process def: "The directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] subset: goslim_pir subset: goslim_yeast synonym: "nucleobase, nucleoside, nucleotide and nucleic acid transport" RELATED [GOC:dph, GOC:tb] is_a: GO:0071702 ! organic substance transport is_a: GO:0071705 ! nitrogen compound transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:61120 ! nucleobase-containing molecular entity relationship: has_primary_input CHEBI:61120 ! nucleobase-containing molecular entity [Term] id: GO:0015932 name: nucleobase-containing compound transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of nucleobases, nucleosides, nucleotides and nucleic acids from one side of a membrane to the other." [GOC:ai] synonym: "nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity" RELATED [GOC:dph, GOC:tb] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:61120 ! nucleobase-containing molecular entity relationship: has_primary_input CHEBI:61120 ! nucleobase-containing molecular entity relationship: part_of GO:0015931 ! nucleobase-containing compound transport [Term] id: GO:0015980 name: energy derivation by oxidation of organic compounds namespace: biological_process def: "The chemical reactions and pathways by which a cell derives energy from organic compounds; results in the oxidation of the compounds from which energy is released." [GOC:mah] synonym: "chemoorganotrophy" EXACT [] is_a: GO:0006091 ! generation of precursor metabolites and energy [Term] id: GO:0016020 name: membrane namespace: cellular_component alt_id: GO:0016021 alt_id: GO:0098589 alt_id: GO:0098805 def: "A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it." [GOC:dos, GOC:mah, ISBN:0815316194] subset: goslim_candida subset: goslim_chembl subset: goslim_flybase_ribbon subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant subset: goslim_yeast synonym: "integral component of membrane" NARROW [] synonym: "integral to membrane" NARROW [] synonym: "membrane region" NARROW [] synonym: "region of membrane" NARROW [] synonym: "transmembrane" RELATED [GOC:mah] synonym: "whole membrane" NARROW [] xref: Wikipedia:Biological_membrane xref: Wikipedia:Transmembrane_protein is_a: GO:0110165 ! cellular anatomical entity disjoint_from: GO:0031012 ! extracellular matrix creation_date: 2014-03-06T11:37:54Z [Term] id: GO:0016042 name: lipid catabolic process namespace: biological_process alt_id: GO:0006724 alt_id: GO:0044240 def: "The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent." [GOC:go_curators] synonym: "lipid breakdown" EXACT [] synonym: "lipid catabolism" EXACT [] synonym: "lipid degradation" EXACT [] synonym: "lipolysis" EXACT [] synonym: "multicellular organism lipid catabolic process" NARROW [] synonym: "multicellular organismal lipid catabolic process" NARROW [] xref: Wikipedia:Lipid_catabolism is_a: GO:0006629 ! lipid metabolic process is_a: GO:1901575 ! organic substance catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:18059 ! lipid relationship: has_primary_input CHEBI:18059 ! lipid [Term] id: GO:0016043 name: cellular component organization namespace: biological_process alt_id: GO:0044235 alt_id: GO:0071842 def: "A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component." [GOC:ai, GOC:jl, GOC:mah] subset: goslim_agr subset: goslim_mouse subset: goslim_pir subset: goslim_plant synonym: "cell organisation" EXACT [] synonym: "cell organization and biogenesis" RELATED [GOC:mah] synonym: "cellular component organisation at cellular level" EXACT [GOC:mah] synonym: "cellular component organisation in other organism" EXACT [GOC:mah] synonym: "cellular component organization at cellular level" EXACT [] synonym: "cellular component organization in other organism" EXACT [] is_a: GO:0071840 ! cellular component organization or biogenesis intersection_of: GO:0009987 ! cellular process intersection_of: results_in_organization_of GO:0005575 ! cellular_component relationship: results_in_organization_of GO:0005575 ! cellular_component [Term] id: GO:0016049 name: cell growth namespace: biological_process alt_id: GO:0048591 def: "The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present." [GOC:ai] subset: gocheck_do_not_annotate subset: goslim_drosophila subset: goslim_pir subset: goslim_plant synonym: "cell expansion" RELATED [] synonym: "cellular growth" EXACT [] synonym: "growth of cell" EXACT [] synonym: "metabolic process resulting in cell growth" RELATED [] synonym: "metabolism resulting in cell growth" RELATED [] synonym: "non-developmental cell growth" RELATED [GOC:mah] synonym: "non-developmental growth of a unicellular organism" RELATED [GOC:mah] is_a: GO:0009987 ! cellular process is_a: GO:0040007 ! growth intersection_of: GO:0040007 ! growth intersection_of: results_in_growth_of CL:0000000 ! cell relationship: results_in_growth_of CL:0000000 ! cell [Term] id: GO:0016050 name: vesicle organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle." [GOC:mah] subset: goslim_pir subset: goslim_yeast synonym: "vesicle organisation" EXACT [] synonym: "vesicle organization and biogenesis" RELATED [GOC:mah] is_a: GO:0006996 ! organelle organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0031982 ! vesicle relationship: results_in_organization_of GO:0031982 ! vesicle [Term] id: GO:0016051 name: carbohydrate biosynthetic process namespace: biological_process alt_id: GO:0006093 def: "The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y." [ISBN:0198506732] synonym: "anabolic carbohydrate metabolic process" EXACT [] synonym: "anabolic carbohydrate metabolism" EXACT [] synonym: "carbohydrate anabolism" EXACT [] synonym: "carbohydrate biosynthesis" EXACT [] synonym: "carbohydrate formation" EXACT [] synonym: "carbohydrate synthesis" EXACT [] is_a: GO:0005975 ! carbohydrate metabolic process is_a: GO:1901576 ! organic substance biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:16646 ! carbohydrate relationship: has_primary_output CHEBI:16646 ! carbohydrate [Term] id: GO:0016052 name: carbohydrate catabolic process namespace: biological_process alt_id: GO:0006095 alt_id: GO:0044276 alt_id: GO:0044724 def: "The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y." [ISBN:0198506732] synonym: "carbohydrate breakdown" EXACT [] synonym: "carbohydrate catabolism" EXACT [] synonym: "carbohydrate degradation" EXACT [] synonym: "catabolic carbohydrate metabolic process" EXACT [] synonym: "catabolic carbohydrate metabolism" EXACT [] synonym: "multicellular organismal carbohydrate catabolic process" NARROW [] synonym: "single-organism carbohydrate catabolic process" RELATED [] is_a: GO:0005975 ! carbohydrate metabolic process is_a: GO:1901575 ! organic substance catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:16646 ! carbohydrate relationship: has_primary_input CHEBI:16646 ! carbohydrate created_by: jl creation_date: 2012-10-23T16:34:39Z [Term] id: GO:0016053 name: organic acid biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of organic acids, any acidic compound containing carbon in covalent linkage." [ISBN:0198506732] synonym: "organic acid anabolism" EXACT [] synonym: "organic acid biosynthesis" EXACT [] synonym: "organic acid formation" EXACT [] synonym: "organic acid synthesis" EXACT [] is_a: GO:0006082 ! organic acid metabolic process is_a: GO:0044249 ! cellular biosynthetic process is_a: GO:0044283 ! small molecule biosynthetic process is_a: GO:1901576 ! organic substance biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:64709 ! organic acid relationship: has_primary_output CHEBI:64709 ! organic acid [Term] id: GO:0016054 name: organic acid catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage." [ISBN:0198506732] synonym: "organic acid breakdown" EXACT [] synonym: "organic acid catabolism" EXACT [] synonym: "organic acid degradation" EXACT [] is_a: GO:0006082 ! organic acid metabolic process is_a: GO:0044248 ! cellular catabolic process is_a: GO:0044282 ! small molecule catabolic process is_a: GO:1901575 ! organic substance catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:64709 ! organic acid relationship: has_primary_input CHEBI:64709 ! organic acid [Term] id: GO:0016057 name: regulation of membrane potential in photoreceptor cell namespace: biological_process def: "Hyperpolarization (vertebrates) or depolarization (invertebrates) of the photoreceptor cell membrane via closing/opening of cation specific channels as a result of signals generated by rhodopsin activation by a photon." [GOC:dph, GOC:hb, GOC:tb] synonym: "changes in polarization state of photoreceptor cell membrane" EXACT [GOC:dph, GOC:tb] is_a: GO:0042391 ! regulation of membrane potential intersection_of: GO:0042391 ! regulation of membrane potential intersection_of: occurs_in CL:0000210 ! photoreceptor cell relationship: occurs_in CL:0000210 ! photoreceptor cell [Term] id: GO:0016070 name: RNA metabolic process namespace: biological_process def: "The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage." [ISBN:0198506732] subset: goslim_agr subset: goslim_candida subset: goslim_metagenomics subset: goslim_pir subset: goslim_prokaryote synonym: "RNA metabolism" EXACT [] is_a: GO:0090304 ! nucleic acid metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:33697 ! ribonucleic acid relationship: has_primary_input_or_output CHEBI:33697 ! ribonucleic acid [Term] id: GO:0016192 name: vesicle-mediated transport namespace: biological_process alt_id: GO:0006899 def: "A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane." [GOC:ai, GOC:mah, ISBN:08789310662000] subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_pir subset: goslim_pombe synonym: "nonselective vesicle transport" NARROW [] synonym: "protein sorting along secretory pathway" RELATED [] synonym: "vesicle trafficking" RELATED [] synonym: "vesicle transport" EXACT [] synonym: "vesicular transport" EXACT [GOC:mah] is_a: GO:0006810 ! transport is_a: GO:0009987 ! cellular process intersection_of: GO:0006810 ! transport intersection_of: process_has_causal_agent GO:0031982 ! vesicle relationship: process_has_causal_agent GO:0031982 ! vesicle property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/25421" xsd:anyURI [Term] id: GO:0016202 name: regulation of striated muscle tissue development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of striated muscle development." [GOC:go_curators] is_a: GO:0048634 ! regulation of muscle organ development is_a: GO:1901861 ! regulation of muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0014706 ! striated muscle tissue development relationship: regulates GO:0014706 ! striated muscle tissue development [Term] id: GO:0016301 name: kinase activity namespace: molecular_function def: "Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." [ISBN:0198506732] comment: Note that this term encompasses all activities that transfer a single phosphate group; although ATP is by far the most common phosphate donor, reactions using other phosphate donors are included in this term. subset: goslim_chembl subset: goslim_drosophila subset: goslim_metagenomics subset: goslim_plant subset: goslim_yeast synonym: "phosphokinase activity" EXACT [] xref: Reactome:R-HSA-6788855 "FN3KRP phosphorylates PsiAm, RibAm" xref: Reactome:R-HSA-6788867 "FN3K phosphorylates ketosamines" is_a: GO:0016772 ! transferase activity, transferring phosphorus-containing groups [Term] id: GO:0016310 name: phosphorylation namespace: biological_process def: "The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide." [ISBN:0198506732] subset: goslim_chembl subset: goslim_metagenomics xref: Wikipedia:Phosphorylation is_a: GO:0006796 ! phosphate-containing compound metabolic process [Term] id: GO:0016321 name: female meiosis chromosome segregation namespace: biological_process def: "The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a female." [GOC:ai] is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0045132 ! meiotic chromosome segregation intersection_of: GO:0098813 ! nuclear chromosome segregation intersection_of: part_of GO:0007143 ! female meiotic nuclear division relationship: part_of GO:0007143 ! female meiotic nuclear division [Term] id: GO:0016325 name: oocyte microtubule cytoskeleton organization namespace: biological_process alt_id: GO:0048130 def: "Formation and maintenance of a polarized microtubule array originating from a microtubule-organizing center (MTOC) in the oocyte. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, PMID:11231123] synonym: "oocyte microtubule cytoskeleton organisation" EXACT [] is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0030951 ! establishment or maintenance of microtubule cytoskeleton polarity intersection_of: GO:0016043 ! cellular component organization intersection_of: occurs_in CL:0000023 ! oocyte intersection_of: results_in_organization_of GO:0015630 ! microtubule cytoskeleton relationship: occurs_in CL:0000023 ! oocyte relationship: part_of GO:0007308 ! oocyte construction [Term] id: GO:0016331 name: morphogenesis of embryonic epithelium namespace: biological_process def: "The process in which the anatomical structures of embryonic epithelia are generated and organized." [GOC:jl] is_a: GO:0002009 ! morphogenesis of an epithelium is_a: GO:0048598 ! embryonic morphogenesis [Term] id: GO:0016477 name: cell migration namespace: biological_process def: "The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues." [GOC:cjm, GOC:dph, GOC:ems, GOC:pf, Wikipedia:Cell_migration] xref: Wikipedia:Cell_migration is_a: GO:0048870 ! cell motility property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24787" xsd:anyURI property_value: RO:0002161 NCBITaxon:4890 [Term] id: GO:0016525 name: negative regulation of angiogenesis namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis." [GOC:go_curators] synonym: "down regulation of angiogenesis" EXACT [] synonym: "down-regulation of angiogenesis" EXACT [] synonym: "downregulation of angiogenesis" EXACT [] synonym: "inhibition of angiogenesis" NARROW [] is_a: GO:0045765 ! regulation of angiogenesis is_a: GO:2000181 ! negative regulation of blood vessel morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001525 ! angiogenesis relationship: negatively_regulates GO:0001525 ! angiogenesis [Term] id: GO:0016528 name: sarcoplasm namespace: cellular_component def: "The cytoplasm of a muscle cell; includes the sarcoplasmic reticulum." [ISBN:0198547684] xref: Wikipedia:Sarcoplasm is_a: GO:0005737 ! cytoplasm is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: GO:0005737 ! cytoplasm intersection_of: part_of CL:0000187 ! muscle cell relationship: part_of CL:0000187 ! muscle cell property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0016740 name: transferase activity namespace: molecular_function def: "Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2." [ISBN:0198506732] subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_metagenomics subset: goslim_mouse subset: goslim_pir subset: goslim_plant subset: goslim_prokaryote subset: goslim_yeast xref: EC:2.-.-.- xref: Reactome:R-HSA-1483089 "PE is converted to PS by PTDSS2" xref: Reactome:R-HSA-1483186 "PC is converted to PS by PTDSS1" xref: Reactome:R-HSA-5668414 "TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK" xref: Reactome:R-HSA-8868783 "TSR3 transfers aminocarboxypropyl group from S-adenosylmethionine to N(1)-methylpseudouridine-1248 of 18SE rRNA yielding N(1)-methyl-N(3)-aminocarboxypropylpseudouridine-1248" is_a: GO:0003824 ! catalytic activity [Term] id: GO:0016772 name: transferase activity, transferring phosphorus-containing groups namespace: molecular_function def: "Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor)." [GOC:jl, ISBN:0198506732] comment: Note that this term encompasses all kinase activities, as well as activities that transfer other phosphorus-containing groups such as diphosphate or nucleotides. subset: goslim_chembl xref: EC:2.7.-.- is_a: GO:0016740 ! transferase activity [Term] id: GO:0016787 name: hydrolase activity namespace: molecular_function def: "Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc." [ISBN:0198506732] subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_metagenomics subset: goslim_mouse subset: goslim_pir subset: goslim_plant subset: goslim_prokaryote subset: goslim_yeast xref: EC:3.-.-.- xref: Reactome:R-HSA-1236938 "Partial proteolysis of antigen in phagolysosomes" xref: Reactome:R-HSA-2029475 "Production of AA by iPLA2 upon FCGR activation" xref: Reactome:R-HSA-5694583 "ABHD4 hydrolyses NAPE" xref: Reactome:R-HSA-5695964 "ABHD14B hydrolyses PNPB" xref: Reactome:R-HSA-6786190 "CMBL hydrolyses OM to OLMS" xref: Reactome:R-HSA-6788295 "HDHD1:Mg2+ dephosphorylates PURIDP" xref: Reactome:R-HSA-8938314 "ENPPs hydrolyse CoA-SH to PPANT, PAP" xref: Reactome:R-HSA-8952137 "Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate" is_a: GO:0003824 ! catalytic activity [Term] id: GO:0016788 name: hydrolase activity, acting on ester bonds namespace: molecular_function def: "Catalysis of the hydrolysis of any ester bond." [GOC:jl] subset: goslim_chembl synonym: "esterase activity" EXACT [] xref: EC:3.1.-.- xref: Reactome:R-HSA-162729 "uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid" xref: Reactome:R-HSA-9023617 "Butyrylcholinesterase hydrolyzes acyl Ghrelin" xref: Reactome:R-HSA-9023619 "Platelet-activating factor acetylhydrolase (PLA2G7) hydrolyzes acyl Ghrelin" xref: Reactome:R-HSA-9749609 "BCHE hydrolyzes ASA-" is_a: GO:0016787 ! hydrolase activity [Term] id: GO:0017085 name: response to insecticide namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insecticide stimulus. Insecticides are chemicals used to kill insects." [GOC:curators] synonym: "insecticide resistance" RELATED [] synonym: "insecticide susceptibility/resistance" RELATED [] is_a: GO:0009636 ! response to toxic substance [Term] id: GO:0017126 name: nucleologenesis namespace: biological_process def: "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a nucleolus, a small, dense body one or more of which are present in the nucleus of eukaryotic cells." [GOC:jl, ISBN:0198506732] synonym: "nucleolus assembly" NARROW [GOC:mah] synonym: "nucleolus biogenesis" EXACT [] is_a: GO:0007000 ! nucleolus organization is_a: GO:0044085 ! cellular component biogenesis intersection_of: GO:0044085 ! cellular component biogenesis intersection_of: has_primary_output GO:0005730 ! nucleolus relationship: has_primary_output GO:0005730 ! nucleolus [Term] id: GO:0017145 name: stem cell division namespace: biological_process def: "The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or adult, that can undergo unlimited division and give rise to one or several different cell types." [GOC:jid, ISBN:0582227089] synonym: "stem cell renewal" EXACT [] is_a: GO:0051301 ! cell division intersection_of: GO:0051301 ! cell division intersection_of: has_primary_input CL:0000034 ! stem cell relationship: has_primary_input CL:0000034 ! stem cell property_value: RO:0002161 NCBITaxon_Union:0000023 [Term] id: GO:0017148 name: negative regulation of translation namespace: biological_process alt_id: GO:0016478 def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA." [GOC:isa_complete] synonym: "down regulation of protein biosynthetic process" EXACT [] synonym: "down-regulation of protein biosynthetic process" EXACT [] synonym: "downregulation of protein biosynthetic process" EXACT [] synonym: "inhibition of protein biosynthetic process" NARROW [] synonym: "negative regulation of protein anabolism" EXACT [] synonym: "negative regulation of protein biosynthesis" EXACT [] synonym: "negative regulation of protein biosynthetic process" EXACT [] synonym: "negative regulation of protein formation" EXACT [] synonym: "negative regulation of protein synthesis" EXACT [] synonym: "protein biosynthesis inhibitor activity" RELATED [] synonym: "protein biosynthetic process inhibitor activity" RELATED [] is_a: GO:0006417 ! regulation of translation is_a: GO:0010629 ! negative regulation of gene expression is_a: GO:0034249 ! negative regulation of amide metabolic process is_a: GO:0051248 ! negative regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006412 ! translation relationship: negatively_regulates GO:0006412 ! translation [Term] id: GO:0017157 name: regulation of exocytosis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of exocytosis." [GOC:go_curators] is_a: GO:0060627 ! regulation of vesicle-mediated transport is_a: GO:1903530 ! regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006887 ! exocytosis relationship: regulates GO:0006887 ! exocytosis [Term] id: GO:0018130 name: heterocycle biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings)." [ISBN:0198547684] synonym: "heterocycle anabolism" EXACT [] synonym: "heterocycle biosynthesis" EXACT [] synonym: "heterocycle formation" EXACT [] synonym: "heterocycle synthesis" EXACT [] is_a: GO:0044249 ! cellular biosynthetic process is_a: GO:0046483 ! heterocycle metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:5686 ! heterocyclic compound relationship: has_primary_output CHEBI:5686 ! heterocyclic compound [Term] id: GO:0018958 name: phenol-containing compound metabolic process namespace: biological_process def: "The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring." [ISBN:0198506732] comment: Note that phenol metabolism is not included as a child of 'xenobiotic metabolism' because although it is synthesized industrially, phenol is also found naturally in animal wastes and other organic materials. It is often formed by the activity of microorganisms, which can chemically modify a variety of xenobiotic and naturally occurring phenolic compounds. synonym: "carbolic acid metabolic process" EXACT [] synonym: "carbolic acid metabolism" EXACT [] synonym: "hydroxybenzene metabolic process" EXACT [] synonym: "hydroxybenzene metabolism" EXACT [] synonym: "phenol-containing compound metabolism" EXACT [] xref: UM-BBD_pathwayID:phe is_a: GO:0006725 ! cellular aromatic compound metabolic process is_a: GO:1901360 ! organic cyclic compound metabolic process is_a: GO:1901615 ! organic hydroxy compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:33853 ! phenols relationship: has_primary_input_or_output CHEBI:33853 ! phenols [Term] id: GO:0019098 name: reproductive behavior namespace: biological_process alt_id: GO:0033057 alt_id: GO:0044704 alt_id: GO:0044705 def: "The specific behavior of an organism that is associated with reproduction." [GOC:jl, GOC:pr] synonym: "multi-organism reproductive behavior" NARROW [] synonym: "multicellular organism reproductive behavior" NARROW [] synonym: "reproductive behavior in a multicellular organism" EXACT [] synonym: "reproductive behaviour" EXACT [] synonym: "single-organism reproductive behavior" RELATED [] is_a: GO:0007610 ! behavior is_a: GO:0022414 ! reproductive process intersection_of: GO:0007610 ! behavior intersection_of: part_of GO:0032504 ! multicellular organism reproduction relationship: part_of GO:0032504 ! multicellular organism reproduction property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23491" xsd:anyURI created_by: jl creation_date: 2012-09-19T16:01:37Z [Term] id: GO:0019216 name: regulation of lipid metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids." [GOC:go_curators] synonym: "regulation of lipid metabolism" EXACT [] is_a: GO:0080090 ! regulation of primary metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006629 ! lipid metabolic process relationship: regulates GO:0006629 ! lipid metabolic process [Term] id: GO:0019218 name: regulation of steroid metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving steroids." [GOC:go_curators] synonym: "regulation of steroid metabolism" EXACT [] is_a: GO:0019216 ! regulation of lipid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0008202 ! steroid metabolic process relationship: regulates GO:0008202 ! steroid metabolic process [Term] id: GO:0019219 name: regulation of nucleobase-containing compound metabolic process namespace: biological_process def: "Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:go_curators] synonym: "regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" RELATED [GOC:dph, GOC:tb] synonym: "regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism" EXACT [] is_a: GO:0031323 ! regulation of cellular metabolic process is_a: GO:0051171 ! regulation of nitrogen compound metabolic process is_a: GO:0080090 ! regulation of primary metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006139 ! nucleobase-containing compound metabolic process relationship: regulates GO:0006139 ! nucleobase-containing compound metabolic process [Term] id: GO:0019220 name: regulation of phosphate metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates." [GOC:go_curators] synonym: "regulation of phosphate metabolism" EXACT [] is_a: GO:0051174 ! regulation of phosphorus metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006796 ! phosphate-containing compound metabolic process relationship: regulates GO:0006796 ! phosphate-containing compound metabolic process [Term] id: GO:0019222 name: regulation of metabolic process namespace: biological_process alt_id: GO:0044246 def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." [GOC:go_curators] subset: goslim_metagenomics synonym: "regulation of metabolism" EXACT [] synonym: "regulation of multicellular organismal metabolic process" NARROW [] synonym: "regulation of organismal metabolic process" NARROW [GOC:tb] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0008152 ! metabolic process relationship: regulates GO:0008152 ! metabolic process [Term] id: GO:0019226 name: transmission of nerve impulse namespace: biological_process def: "The neurological system process in which a signal is transmitted through the nervous system by a combination of action potential propagation and synaptic transmission." [GOC:curators, ISBN:0815316194] synonym: "conduction of nerve impulse" EXACT [GOC:dph] synonym: "signal transmission along a neuron" EXACT [] is_a: GO:0050877 ! nervous system process relationship: has_part GO:0001508 ! action potential relationship: has_part GO:0007268 ! chemical synaptic transmission relationship: part_of GO:0007154 ! cell communication [Term] id: GO:0019228 name: neuronal action potential namespace: biological_process def: "An action potential that occurs in a neuron." [GOC:dph, GOC:isa_complete, GOC:tb] synonym: "generation of action potential" RELATED [GOC:dph, GOC:tb] is_a: GO:0001508 ! action potential intersection_of: GO:0001508 ! action potential intersection_of: occurs_in CL:0000540 ! neuron relationship: occurs_in CL:0000540 ! neuron relationship: part_of GO:0019226 ! transmission of nerve impulse [Term] id: GO:0019233 name: sensory perception of pain namespace: biological_process def: "The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process." [GOC:curators] synonym: "nociception" RELATED [] synonym: "perception of physiological pain" NARROW [] xref: Wikipedia:Nociception is_a: GO:0007600 ! sensory perception [Term] id: GO:0019318 name: hexose metabolic process namespace: biological_process def: "The chemical reactions and pathways involving a hexose, any monosaccharide with a chain of six carbon atoms in the molecule." [ISBN:0198506732] synonym: "hexose metabolism" EXACT [] is_a: GO:0005996 ! monosaccharide metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:18133 ! hexose relationship: has_primary_input_or_output CHEBI:18133 ! hexose [Term] id: GO:0019319 name: hexose biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of hexose, any monosaccharide with a chain of six carbon atoms in the molecule." [ISBN:0198506732] synonym: "hexose anabolism" EXACT [] synonym: "hexose biosynthesis" EXACT [] synonym: "hexose formation" EXACT [] synonym: "hexose synthesis" EXACT [] is_a: GO:0019318 ! hexose metabolic process is_a: GO:0046364 ! monosaccharide biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:18133 ! hexose relationship: has_primary_output CHEBI:18133 ! hexose [Term] id: GO:0019320 name: hexose catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of hexose, any monosaccharide with a chain of six carbon atoms in the molecule." [ISBN:0198506732] synonym: "hexose breakdown" EXACT [] synonym: "hexose catabolism" EXACT [] synonym: "hexose degradation" EXACT [] is_a: GO:0019318 ! hexose metabolic process is_a: GO:0046365 ! monosaccharide catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:18133 ! hexose relationship: has_primary_input CHEBI:18133 ! hexose [Term] id: GO:0019336 name: phenol-containing compound catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring." [ISBN:0198506732] synonym: "phenol-containing compound breakdown" EXACT [] synonym: "phenol-containing compound catabolism" EXACT [] synonym: "phenol-containing compound degradation" EXACT [] xref: MetaCyc:PHENOLDEG-PWY is_a: GO:0018958 ! phenol-containing compound metabolic process is_a: GO:0019439 ! aromatic compound catabolic process is_a: GO:1901361 ! organic cyclic compound catabolic process is_a: GO:1901616 ! organic hydroxy compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:33853 ! phenols relationship: has_primary_input CHEBI:33853 ! phenols [Term] id: GO:0019413 name: acetate biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of acetate, the anion of acetic acid." [GOC:go_curators] synonym: "acetate anabolism" EXACT [] synonym: "acetate biosynthesis" EXACT [] synonym: "acetate formation" EXACT [] synonym: "acetate synthesis" EXACT [] is_a: GO:0006083 ! acetate metabolic process is_a: GO:0072330 ! monocarboxylic acid biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:30089 ! acetate relationship: has_primary_output CHEBI:30089 ! acetate [Term] id: GO:0019438 name: aromatic compound biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of aromatic compounds, any substance containing an aromatic carbon ring." [GOC:ai] synonym: "aromatic compound anabolism" EXACT [] synonym: "aromatic compound biosynthesis" EXACT [] synonym: "aromatic compound formation" EXACT [] synonym: "aromatic compound synthesis" EXACT [] synonym: "aromatic hydrocarbon biosynthesis" NARROW [] synonym: "aromatic hydrocarbon biosynthetic process" NARROW [] is_a: GO:0006725 ! cellular aromatic compound metabolic process is_a: GO:0044249 ! cellular biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:33655 ! aromatic compound relationship: has_primary_output CHEBI:33655 ! aromatic compound [Term] id: GO:0019439 name: aromatic compound catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of aromatic compounds, any substance containing an aromatic carbon ring." [GOC:ai] synonym: "aromatic compound breakdown" EXACT [] synonym: "aromatic compound catabolism" EXACT [] synonym: "aromatic compound degradation" EXACT [] synonym: "aromatic hydrocarbon catabolic process" NARROW [] synonym: "aromatic hydrocarbon catabolism" NARROW [] is_a: GO:0006725 ! cellular aromatic compound metabolic process is_a: GO:0044248 ! cellular catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:33655 ! aromatic compound relationship: has_primary_input CHEBI:33655 ! aromatic compound [Term] id: GO:0019538 name: protein metabolic process namespace: biological_process alt_id: GO:0006411 alt_id: GO:0044267 alt_id: GO:0044268 def: "The chemical reactions and pathways involving a protein. Includes protein modification." [GOC:ma] subset: goslim_agr subset: goslim_flybase_ribbon subset: goslim_mouse subset: goslim_pir subset: goslim_plant synonym: "cellular protein metabolic process" EXACT [] synonym: "cellular protein metabolism" EXACT [] synonym: "multicellular organismal protein metabolic process" NARROW [] synonym: "protein metabolic process and modification" EXACT [] synonym: "protein metabolism" EXACT [] synonym: "protein metabolism and modification" EXACT [] xref: Wikipedia:Protein_metabolism is_a: GO:0044238 ! primary metabolic process is_a: GO:1901564 ! organonitrogen compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output PR:000000001 ! protein relationship: has_primary_input_or_output PR:000000001 ! protein property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23112" xsd:anyURI [Term] id: GO:0019614 name: catechol-containing compound catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent." [GOC:go_curators] synonym: "catechol breakdown" RELATED [] synonym: "catechol catabolic process" RELATED [] synonym: "catechol catabolism" RELATED [] synonym: "catechol degradation" RELATED [] is_a: GO:0009712 ! catechol-containing compound metabolic process is_a: GO:0019336 ! phenol-containing compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:33566 ! catechols relationship: has_primary_input CHEBI:33566 ! catechols [Term] id: GO:0019725 name: cellular homeostasis namespace: biological_process def: "Any process involved in the maintenance of an internal steady state at the level of the cell." [GOC:isa_complete, GOC:jl, ISBN:0395825172] subset: goslim_candida subset: goslim_plant is_a: GO:0042592 ! homeostatic process intersection_of: GO:0042592 ! homeostatic process intersection_of: occurs_in CL:0000000 ! cell disjoint_from: GO:0048872 ! homeostasis of number of cells relationship: in_taxon NCBITaxon:131567 {all_only="true"} ! cellular organisms relationship: occurs_in CL:0000000 ! cell relationship: only_in_taxon NCBITaxon:131567 ! cellular organisms [Term] id: GO:0019748 name: secondary metabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients." [GOC:go_curators] subset: goslim_chembl subset: goslim_pir subset: goslim_plant subset: goslim_pombe synonym: "secondary metabolism" EXACT [] synonym: "secondary metabolite metabolic process" EXACT [] synonym: "secondary metabolite metabolism" EXACT [] xref: Wikipedia:Secondary_metabolism is_a: GO:0008152 ! metabolic process [Term] id: GO:0019752 name: carboxylic acid metabolic process namespace: biological_process def: "The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-)." [ISBN:0198506732] synonym: "carboxylic acid metabolism" EXACT [] is_a: GO:0043436 ! oxoacid metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:29067 ! carboxylic acid anion relationship: has_primary_input_or_output CHEBI:29067 ! carboxylic acid anion [Term] id: GO:0019755 name: one-carbon compound transport namespace: biological_process def: "The directed movement of one-carbon compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "one carbon compound transport" EXACT [] is_a: GO:0071702 ! organic substance transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:64708 ! one-carbon compound relationship: has_primary_input CHEBI:64708 ! one-carbon compound [Term] id: GO:0019827 name: stem cell population maintenance namespace: biological_process def: "The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types." [GOC:mah, ISBN:0878932437] synonym: "maintenance of pluripotency" RELATED [GOC:vk] is_a: GO:0032501 ! multicellular organismal process is_a: GO:0098727 ! maintenance of cell number intersection_of: GO:0098727 ! maintenance of cell number intersection_of: acts_on_population_of CL:0000034 ! stem cell relationship: acts_on_population_of CL:0000034 ! stem cell [Term] id: GO:0019867 name: outer membrane namespace: cellular_component def: "The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites." [GOC:go_curators] subset: goslim_metagenomics is_a: GO:0016020 ! membrane [Term] id: GO:0019882 name: antigen processing and presentation namespace: biological_process alt_id: GO:0030333 def: "The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex." [GO_REF:0000022, GOC:add, ISBN:0781735149, PMID:15771591, PMID:15928678] synonym: "antigen presentation" EXACT [] synonym: "antigen processing" EXACT [] xref: Wikipedia:Antigen_presentation is_a: GO:0002376 ! immune system process [Term] id: GO:0019953 name: sexual reproduction namespace: biological_process def: "A type of reproduction that combines the genetic material of two gametes (such as a sperm or egg cell or fungal spores). The gametes have an haploid genome (with a single set of chromosomes, the product of a meiotic division) and combines with one another to produce a zygote (diploid)." [Wikipedia:Sexual_reproduction] comment: Note that gametes may come from two organisms or from a single organism in the case of self-fertilizing hermaphrodites, e.g. C. elegans, or self-fertilization in plants. Note also that sexual reproduction may be seen as the regular alternation, in the life cycle of haplontic, diplontic and diplohaplontic organisms, of meiosis and fertilization which provides for the production offspring. In diplontic organisms there is a life cycle in which the products of meiosis behave directly as gametes, fusing to form a zygote from which the diploid, or sexually reproductive polyploid, adult organism will develop. In diplohaplontic organisms a haploid phase (gametophyte) exists in the life cycle between meiosis and fertilization (e.g. higher plants, many algae and Fungi); the products of meiosis are spores that develop as haploid individuals from which haploid gametes develop to form a diploid zygote; diplohaplontic organisms show an alternation of haploid and diploid generations. In haplontic organisms meiosis occurs in the zygote, giving rise to four haploid cells (e.g. many algae and protozoa), only the zygote is diploid and this may form a resistant spore, tiding organisms over hard times. xref: Wikipedia:Sexual_reproduction is_a: GO:0000003 ! reproduction property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22929" xsd:anyURI [Term] id: GO:0021501 name: prechordal plate formation namespace: biological_process def: "The formation of the prechordal plate. The prechordal plate is a thickening of the endoderm at the cranial end of the primitive streak formed by the involution of Spemann's organizer cells. The prechordal plate and the notochord induce the formation of the neural plate from the overlying ectodermal cells." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0003063 ! prechordal plate relationship: part_of GO:0007399 ! nervous system development relationship: results_in_formation_of_anatomical_entity UBERON:0003063 ! prechordal plate [Term] id: GO:0021510 name: spinal cord development namespace: biological_process def: "The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002240 ! spinal cord relationship: part_of GO:0007417 ! central nervous system development relationship: results_in_development_of UBERON:0002240 ! spinal cord [Term] id: GO:0021514 name: ventral spinal cord interneuron differentiation namespace: biological_process def: "The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of ventral spinal cord interneurons. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] is_a: GO:0021515 ! cell differentiation in spinal cord is_a: GO:0021953 ! central nervous system neuron differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: occurs_in UBERON:0002240 ! spinal cord intersection_of: results_in_acquisition_of_features_of CL:0000099 ! interneuron relationship: part_of GO:0021517 ! ventral spinal cord development relationship: results_in_acquisition_of_features_of CL:0000099 ! interneuron [Term] id: GO:0021515 name: cell differentiation in spinal cord namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: occurs_in UBERON:0002240 ! spinal cord relationship: occurs_in UBERON:0002240 ! spinal cord relationship: part_of GO:0021510 ! spinal cord development [Term] id: GO:0021517 name: ventral spinal cord development namespace: biological_process def: "The process whose specific outcome is the progression of the ventral region of the spinal cord over time, from its formation to the mature structure. The neurons of the ventral region of the mature spinal cord participate in motor output." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002257 ! ventral horn of spinal cord relationship: part_of GO:0021510 ! spinal cord development relationship: results_in_development_of UBERON:0002257 ! ventral horn of spinal cord [Term] id: GO:0021522 name: spinal cord motor neuron differentiation namespace: biological_process def: "The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of motor neurons. Motor neurons innervate an effector (muscle or glandular) tissue and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] is_a: GO:0021515 ! cell differentiation in spinal cord is_a: GO:0021953 ! central nervous system neuron differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0011001 ! spinal cord motor neuron relationship: part_of GO:0021517 ! ventral spinal cord development relationship: results_in_acquisition_of_features_of CL:0011001 ! spinal cord motor neuron [Term] id: GO:0021523 name: somatic motor neuron differentiation namespace: biological_process def: "The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of somatic motor neurons. Somatic motor neurons innervate skeletal muscle targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] is_a: GO:0021522 ! spinal cord motor neuron differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0005024 ! somatomotor neuron relationship: results_in_acquisition_of_features_of CL:0005024 ! somatomotor neuron [Term] id: GO:0021532 name: neural tube patterning namespace: biological_process def: "The regionalization process that regulates the coordinated growth that establishes the non-random spatial arrangement of the neural tube." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0003002 ! regionalization relationship: part_of GO:0021915 ! neural tube development [Term] id: GO:0021533 name: cell differentiation in hindbrain namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mature cells of the hindbrain. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: occurs_in UBERON:0002028 ! hindbrain relationship: in_taxon NCBITaxon:89593 {all_only="true"} ! Craniata relationship: occurs_in UBERON:0002028 ! hindbrain relationship: only_in_taxon NCBITaxon:89593 ! Craniata relationship: part_of GO:0030902 ! hindbrain development [Term] id: GO:0021534 name: cell proliferation in hindbrain namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0061351 ! neural precursor cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: occurs_in UBERON:0002028 ! hindbrain relationship: in_taxon NCBITaxon:89593 {all_only="true"} ! Craniata relationship: occurs_in UBERON:0002028 ! hindbrain relationship: only_in_taxon NCBITaxon:89593 ! Craniata relationship: part_of GO:0030902 ! hindbrain development [Term] id: GO:0021535 name: cell migration in hindbrain namespace: biological_process def: "The orderly movement of a cell that will reside in the hindbrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: occurs_in UBERON:0002028 ! hindbrain relationship: in_taxon NCBITaxon:89593 {all_only="true"} ! Craniata relationship: occurs_in UBERON:0002028 ! hindbrain relationship: only_in_taxon NCBITaxon:89593 ! Craniata relationship: part_of GO:0030902 ! hindbrain development [Term] id: GO:0021545 name: cranial nerve development namespace: biological_process def: "The process whose specific outcome is the progression of the cranial nerves over time, from its formation to the mature structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0021675 ! nerve development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001785 ! cranial nerve relationship: results_in_development_of UBERON:0001785 ! cranial nerve [Term] id: GO:0021546 name: rhombomere development namespace: biological_process def: "The process whose specific outcome is the progression of the rhombomere over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001892 ! rhombomere relationship: part_of GO:0030902 ! hindbrain development relationship: results_in_development_of UBERON:0001892 ! rhombomere [Term] id: GO:0021547 name: midbrain-hindbrain boundary initiation namespace: biological_process def: "The regionalization process that gives rise to the midbrain-hindbrain boundary. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:isa_complete, GOC:jid, PMID:15541513] synonym: "isthmus biosynthesis" RELATED [GOC:cls] synonym: "isthmus formation" RELATED [GOC:cls] synonym: "MHB biosynthesis" EXACT [GOC:cls] synonym: "MHB formation" EXACT [GOC:cls] synonym: "midbrain-hindbrain boundary biosynthesis" EXACT [GOC:cls] synonym: "midbrain-hindbrain boundary formation" EXACT [GOC:cls] is_a: GO:0003002 ! regionalization is_a: GO:0048859 ! formation of anatomical boundary intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0003052 ! midbrain-hindbrain boundary relationship: part_of GO:0021999 ! neural plate anterior/posterior regionalization relationship: part_of GO:0030917 ! midbrain-hindbrain boundary development relationship: results_in_formation_of_anatomical_entity UBERON:0003052 ! midbrain-hindbrain boundary [Term] id: GO:0021548 name: pons development namespace: biological_process def: "The process whose specific outcome is the progression of the pons over time, from its formation to the mature structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000988 ! pons relationship: part_of GO:0022037 ! metencephalon development relationship: results_in_development_of UBERON:0000988 ! pons [Term] id: GO:0021550 name: medulla oblongata development namespace: biological_process def: "The process whose specific outcome is the progression of the medulla oblongata over time, from its formation to the mature structure. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "medulla development" RELATED [GOC:cls] synonym: "myelencephalon development" RELATED [GOC:cls] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001896 ! medulla oblongata relationship: part_of GO:0030902 ! hindbrain development relationship: results_in_development_of UBERON:0001896 ! medulla oblongata [Term] id: GO:0021551 name: central nervous system morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the central nervous system is generated and organized. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0582227089] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001017 ! central nervous system relationship: part_of GO:0007417 ! central nervous system development relationship: results_in_morphogenesis_of UBERON:0001017 ! central nervous system [Term] id: GO:0021555 name: midbrain-hindbrain boundary morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the midbrain-hindbrain boundary is generated and organized. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15541513] synonym: "isthmus morphogenesis" EXACT [GOC:cls] synonym: "MHB morphogenesis" EXACT [GOC:cls] is_a: GO:0048598 ! embryonic morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003052 ! midbrain-hindbrain boundary relationship: part_of GO:0030917 ! midbrain-hindbrain boundary development relationship: results_in_morphogenesis_of UBERON:0003052 ! midbrain-hindbrain boundary [Term] id: GO:0021556 name: central nervous system formation namespace: biological_process def: "The process that gives rise to the central nervous system. This process pertains to the initial formation of a structure from unspecified parts. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0582227089] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0001017 ! central nervous system relationship: part_of GO:0021551 ! central nervous system morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0001017 ! central nervous system [Term] id: GO:0021559 name: trigeminal nerve development namespace: biological_process def: "The process whose specific outcome is the progression of the trigeminal nerve over time, from its formation to the mature structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN V development" RELATED [GOC:cls] synonym: "cranial nerve 5 development" EXACT [GOC:cls] synonym: "cranial nerve V development" EXACT [GOC:cls] is_a: GO:0021545 ! cranial nerve development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001645 ! trigeminal nerve relationship: results_in_development_of UBERON:0001645 ! trigeminal nerve [Term] id: GO:0021575 name: hindbrain morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the hindbrain is generated and organized. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "rhombencephalon morphogenesis" RELATED [] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002028 ! hindbrain relationship: part_of GO:0030902 ! hindbrain development relationship: results_in_morphogenesis_of UBERON:0002028 ! hindbrain [Term] id: GO:0021576 name: hindbrain formation namespace: biological_process def: "The process that gives rise to the hindbrain. This process pertains to the initial formation of a structure from unspecified parts. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0002028 ! hindbrain relationship: part_of GO:0021575 ! hindbrain morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0002028 ! hindbrain [Term] id: GO:0021578 name: hindbrain maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for the hindbrain to attain its fully functional state. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of UBERON:0002028 ! hindbrain relationship: part_of GO:0021626 ! central nervous system maturation relationship: part_of GO:0030902 ! hindbrain development relationship: results_in_maturation_of UBERON:0002028 ! hindbrain [Term] id: GO:0021579 name: medulla oblongata morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the medulla oblongata is generated and organized. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "medulla morphogenesis" RELATED [] synonym: "myelencephalon morphogenesis" RELATED [] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001896 ! medulla oblongata relationship: part_of GO:0021550 ! medulla oblongata development relationship: part_of GO:0021575 ! hindbrain morphogenesis relationship: results_in_morphogenesis_of UBERON:0001896 ! medulla oblongata [Term] id: GO:0021580 name: medulla oblongata formation namespace: biological_process def: "The process that gives rise to the medulla oblongata. This process pertains to the initial formation of a structure from unspecified parts. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "medulla biosynthesis" RELATED [] synonym: "medulla formation" RELATED [] synonym: "myelencephalon biosynthesis" RELATED [] synonym: "myelencephalon formation" RELATED [] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0001896 ! medulla oblongata relationship: part_of GO:0021576 ! hindbrain formation relationship: part_of GO:0021579 ! medulla oblongata morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0001896 ! medulla oblongata [Term] id: GO:0021582 name: medulla oblongata maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for the medulla oblongata to attain its fully functional state. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "medulla maturation" RELATED [] synonym: "myelencephalon maturation" RELATED [] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of UBERON:0001896 ! medulla oblongata relationship: part_of GO:0021550 ! medulla oblongata development relationship: part_of GO:0021578 ! hindbrain maturation relationship: results_in_maturation_of UBERON:0001896 ! medulla oblongata [Term] id: GO:0021583 name: pons morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the pons is generated and organized. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000988 ! pons relationship: part_of GO:0021548 ! pons development relationship: part_of GO:0021575 ! hindbrain morphogenesis relationship: results_in_morphogenesis_of UBERON:0000988 ! pons [Term] id: GO:0021584 name: pons formation namespace: biological_process def: "The process that gives rise to the pons. This process pertains to the initial formation of a structure from unspecified parts. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0000988 ! pons relationship: part_of GO:0021576 ! hindbrain formation relationship: part_of GO:0021583 ! pons morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0000988 ! pons [Term] id: GO:0021586 name: pons maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for the pons to attain its fully functional state. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of UBERON:0000988 ! pons relationship: part_of GO:0021548 ! pons development relationship: part_of GO:0021578 ! hindbrain maturation relationship: results_in_maturation_of UBERON:0000988 ! pons [Term] id: GO:0021593 name: rhombomere morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the rhombomere is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001892 ! rhombomere relationship: part_of GO:0021546 ! rhombomere development relationship: results_in_morphogenesis_of UBERON:0001892 ! rhombomere [Term] id: GO:0021594 name: rhombomere formation namespace: biological_process def: "The process that gives rise to the rhombomere. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0001892 ! rhombomere relationship: part_of GO:0021593 ! rhombomere morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0001892 ! rhombomere [Term] id: GO:0021602 name: cranial nerve morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the cranial nerves are generated and organized. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001785 ! cranial nerve relationship: part_of GO:0021545 ! cranial nerve development relationship: results_in_morphogenesis_of UBERON:0001785 ! cranial nerve [Term] id: GO:0021603 name: cranial nerve formation namespace: biological_process def: "The process that gives rise to the cranial nerves. This process pertains to the initial formation of a structure from unspecified parts. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0001785 ! cranial nerve relationship: part_of GO:0021602 ! cranial nerve morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0001785 ! cranial nerve [Term] id: GO:0021605 name: cranial nerve maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for a cranial nerve to attain its fully functional state. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0021682 ! nerve maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of UBERON:0001785 ! cranial nerve relationship: part_of GO:0021545 ! cranial nerve development relationship: results_in_maturation_of UBERON:0001785 ! cranial nerve [Term] id: GO:0021626 name: central nervous system maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for the central nervous system to attain its fully functional state. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0582227089] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of UBERON:0001017 ! central nervous system relationship: part_of GO:0007417 ! central nervous system development relationship: results_in_maturation_of UBERON:0001017 ! central nervous system [Term] id: GO:0021635 name: trigeminal nerve maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for the trigeminal nerve to attain its fully functional state. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN V maturation" RELATED [] is_a: GO:0021605 ! cranial nerve maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of UBERON:0001645 ! trigeminal nerve relationship: part_of GO:0021559 ! trigeminal nerve development relationship: results_in_maturation_of UBERON:0001645 ! trigeminal nerve [Term] id: GO:0021636 name: trigeminal nerve morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the trigeminal nerve is generated and organized. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN V morphogenesis" RELATED [] is_a: GO:0021602 ! cranial nerve morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001645 ! trigeminal nerve relationship: part_of GO:0021559 ! trigeminal nerve development relationship: results_in_morphogenesis_of UBERON:0001645 ! trigeminal nerve [Term] id: GO:0021638 name: trigeminal nerve formation namespace: biological_process def: "The process that gives rise to the trigeminal nerve. This process pertains to the initial formation of a structure from unspecified parts. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN V biosynthesis" RELATED [] synonym: "CN V formation" RELATED [] is_a: GO:0021603 ! cranial nerve formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0001645 ! trigeminal nerve relationship: part_of GO:0021636 ! trigeminal nerve morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0001645 ! trigeminal nerve [Term] id: GO:0021654 name: rhombomere boundary formation namespace: biological_process def: "The process that gives rise to a rhombomere boundary. This process pertains to the initial formation of a boundary delimiting a rhombomere. Rhombomeres are transverse segments of the developing rhombencephalon that are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0048859 ! formation of anatomical boundary intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0018239 ! rhombomere boundary relationship: part_of GO:0021594 ! rhombomere formation relationship: results_in_formation_of_anatomical_entity UBERON:0018239 ! rhombomere boundary [Term] id: GO:0021675 name: nerve development namespace: biological_process def: "The process whose specific outcome is the progression of a nerve over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001021 ! nerve relationship: part_of GO:0007399 ! nervous system development relationship: results_in_development_of UBERON:0001021 ! nerve [Term] id: GO:0021682 name: nerve maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for a nerve to attain its fully functional state." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of UBERON:0001021 ! nerve relationship: part_of GO:0021675 ! nerve development relationship: results_in_maturation_of UBERON:0001021 ! nerve [Term] id: GO:0021700 name: developmental maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure, cell or cellular component to attain its fully functional state." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] subset: goslim_chembl is_a: GO:0032502 ! developmental process [Term] id: GO:0021703 name: locus ceruleus development namespace: biological_process def: "The process whose specific outcome is the progression of the locus ceruleus over time, from its formation to the mature structure. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "locus caeruleus development" EXACT [] synonym: "locus coeruleus development" EXACT [] is_a: GO:0048857 ! neural nucleus development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002148 ! locus ceruleus relationship: part_of GO:0021548 ! pons development relationship: results_in_development_of UBERON:0002148 ! locus ceruleus [Term] id: GO:0021704 name: locus ceruleus morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the locus ceruleus is generated and organized. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002148 ! locus ceruleus relationship: part_of GO:0021583 ! pons morphogenesis relationship: part_of GO:0021703 ! locus ceruleus development relationship: results_in_morphogenesis_of UBERON:0002148 ! locus ceruleus [Term] id: GO:0021705 name: locus ceruleus formation namespace: biological_process def: "The process that gives rise to the locus ceruleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0002148 ! locus ceruleus relationship: part_of GO:0021584 ! pons formation relationship: part_of GO:0021704 ! locus ceruleus morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0002148 ! locus ceruleus [Term] id: GO:0021706 name: locus ceruleus maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for the locus ceruleus to attain its fully functional state. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of UBERON:0002148 ! locus ceruleus relationship: part_of GO:0021586 ! pons maturation relationship: part_of GO:0021703 ! locus ceruleus development relationship: results_in_maturation_of UBERON:0002148 ! locus ceruleus [Term] id: GO:0021718 name: superior olivary nucleus development namespace: biological_process def: "The process whose specific outcome is the progression of the superior olivary nucleus over time, from its formation to the mature structure. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "superior olive development" RELATED [] is_a: GO:0048857 ! neural nucleus development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0007247 ! nucleus of superior olivary complex relationship: part_of GO:0021548 ! pons development relationship: results_in_development_of UBERON:0007247 ! nucleus of superior olivary complex [Term] id: GO:0021719 name: superior olivary nucleus morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the superior olivary nucleus is generated and organized. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "superior olive morphogenesis" RELATED [] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0007247 ! nucleus of superior olivary complex relationship: part_of GO:0021583 ! pons morphogenesis relationship: part_of GO:0021718 ! superior olivary nucleus development relationship: results_in_morphogenesis_of UBERON:0007247 ! nucleus of superior olivary complex [Term] id: GO:0021720 name: superior olivary nucleus formation namespace: biological_process def: "The process that gives rise to the superior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0007247 ! nucleus of superior olivary complex relationship: part_of GO:0021584 ! pons formation relationship: part_of GO:0021719 ! superior olivary nucleus morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0007247 ! nucleus of superior olivary complex [Term] id: GO:0021722 name: superior olivary nucleus maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for the superior olivary nucleus to attain its fully functional state. The superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "superior olive maturation" RELATED [] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of UBERON:0007247 ! nucleus of superior olivary complex relationship: part_of GO:0021586 ! pons maturation relationship: part_of GO:0021718 ! superior olivary nucleus development relationship: results_in_maturation_of UBERON:0007247 ! nucleus of superior olivary complex [Term] id: GO:0021732 name: midbrain-hindbrain boundary maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15541513] synonym: "isthmus maturation" RELATED [] synonym: "MHB maturation" RELATED [] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of UBERON:0003052 ! midbrain-hindbrain boundary relationship: part_of GO:0030917 ! midbrain-hindbrain boundary development relationship: results_in_maturation_of UBERON:0003052 ! midbrain-hindbrain boundary [Term] id: GO:0021751 name: salivary nucleus development namespace: biological_process def: "The process whose specific outcome is the progression of a salivary nucleus over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0048857 ! neural nucleus development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004133 ! salivatory nucleus relationship: part_of GO:0021548 ! pons development relationship: results_in_development_of UBERON:0004133 ! salivatory nucleus [Term] id: GO:0021753 name: superior salivary nucleus development namespace: biological_process def: "The process whose specific outcome is the progression of the superior salivary nucleus over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0021751 ! salivary nucleus development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002149 ! superior salivatory nucleus relationship: results_in_development_of UBERON:0002149 ! superior salivatory nucleus [Term] id: GO:0021782 name: glial cell development namespace: biological_process def: "The process aimed at the progression of a glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000125 ! glial cell relationship: part_of GO:0010001 ! glial cell differentiation relationship: results_in_development_of CL:0000125 ! glial cell [Term] id: GO:0021903 name: rostrocaudal neural tube patterning namespace: biological_process def: "The process in which the neural tube is divided into specific regions along the rostrocaudal axis." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] synonym: "anterior-posterior neural tube patterning" RELATED [GOC:dph] is_a: GO:0009952 ! anterior/posterior pattern specification relationship: part_of GO:0021532 ! neural tube patterning [Term] id: GO:0021906 name: hindbrain-spinal cord boundary formation namespace: biological_process def: "The process whose specific outcome is the formation of the hindbrain-spinal cord boundary." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] is_a: GO:0048859 ! formation of anatomical boundary intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0005076 ! hindbrain-spinal cord boundary relationship: part_of GO:0021903 ! rostrocaudal neural tube patterning relationship: results_in_formation_of_anatomical_entity UBERON:0005076 ! hindbrain-spinal cord boundary [Term] id: GO:0021915 name: neural tube development namespace: biological_process def: "The process whose specific outcome is the progression of the neural tube over time, from its formation to the mature structure. The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0035295 ! tube development is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001049 ! neural tube relationship: part_of GO:0007399 ! nervous system development relationship: part_of GO:0043009 ! chordate embryonic development relationship: results_in_development_of UBERON:0001049 ! neural tube [Term] id: GO:0021953 name: central nervous system neuron differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the central nervous system." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0030182 ! neuron differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:2000029 ! central nervous system neuron relationship: part_of GO:0007417 ! central nervous system development relationship: results_in_acquisition_of_features_of CL:2000029 ! central nervous system neuron [Term] id: GO:0021954 name: central nervous system neuron development namespace: biological_process def: "The process whose specific outcome is the progression of a neuron whose cell body is located in the central nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0048666 ! neuron development intersection_of: GO:0048468 ! cell development intersection_of: results_in_development_of CL:2000029 ! central nervous system neuron relationship: part_of GO:0021953 ! central nervous system neuron differentiation relationship: results_in_development_of CL:2000029 ! central nervous system neuron [Term] id: GO:0021990 name: neural plate formation namespace: biological_process def: "The formation of the flat, thickened layer of ectodermal cells known as the neural plate. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0878932437, ISBN:0878932585, PMID:15806586] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0003075 ! neural plate relationship: part_of GO:0001839 ! neural plate morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0003075 ! neural plate [Term] id: GO:0021999 name: neural plate anterior/posterior regionalization namespace: biological_process def: "The process that regulates the coordinated growth and differentiation that establishes the non-random anterior-posterior spatial arrangement of the neural plate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] synonym: "neural plate anterior/posterior pattern formation" RELATED [GOC:dph] is_a: GO:0009952 ! anterior/posterior pattern specification is_a: GO:0060897 ! neural plate regionalization [Term] id: GO:0022008 name: neurogenesis namespace: biological_process def: "Generation of cells within the nervous system." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] synonym: "nervous system cell generation" EXACT systematic_synonym [] synonym: "neural cell differentiation" RELATED [GOC:BHF, GOC:dph] xref: Wikipedia:Neurogenesis is_a: GO:0030154 ! cell differentiation relationship: part_of GO:0007399 ! nervous system development [Term] id: GO:0022009 name: central nervous system vasculogenesis namespace: biological_process def: "The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes in the central nervous system. The capillary endothelial cells in the brain are specialized to form the blood-brain barrier." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0001570 ! vasculogenesis intersection_of: GO:0001570 ! vasculogenesis intersection_of: results_in_maturation_of UBERON:0001017 ! central nervous system relationship: results_in_maturation_of UBERON:0001017 ! central nervous system property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/21480" xsd:anyURI [Term] id: GO:0022035 name: rhombomere cell migration namespace: biological_process def: "The movement of a cell within a rhombomere. This process is known to occur as an early step in the generation of anatomical structure from a rhombomere." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15629700] is_a: GO:0021535 ! cell migration in hindbrain intersection_of: GO:0016477 ! cell migration intersection_of: results_in_transport_to_from_or_in UBERON:0001892 ! rhombomere relationship: part_of GO:0021546 ! rhombomere development relationship: results_in_transport_to_from_or_in UBERON:0001892 ! rhombomere [Term] id: GO:0022037 name: metencephalon development namespace: biological_process def: "The process whose specific outcome is the progression of the metencephalon over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001895 ! metencephalon relationship: part_of GO:0030902 ! hindbrain development relationship: results_in_development_of UBERON:0001895 ! metencephalon [Term] id: GO:0022402 name: cell cycle process namespace: biological_process def: "The cellular process that ensures successive accurate and complete genome replication and chromosome segregation." [GOC:isa_complete, GOC:mtg_cell_cycle] subset: gocheck_do_not_annotate is_a: GO:0009987 ! cellular process intersection_of: GO:0009987 ! cellular process intersection_of: part_of GO:0007049 ! cell cycle relationship: part_of GO:0007049 ! cell cycle [Term] id: GO:0022406 name: membrane docking namespace: biological_process def: "The initial attachment of a membrane or protein to a target membrane. Docking requires only that the proteins come close enough to interact and adhere." [GOC:isa_complete, PMID:27875684] subset: goslim_pir is_a: GO:0009987 ! cellular process [Term] id: GO:0022407 name: regulation of cell-cell adhesion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of attachment of a cell to another cell." [GOC:isa_complete] is_a: GO:0030155 ! regulation of cell adhesion intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0098609 ! cell-cell adhesion relationship: regulates GO:0098609 ! cell-cell adhesion [Term] id: GO:0022408 name: negative regulation of cell-cell adhesion namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of cell adhesion to another cell." [GOC:isa_complete] synonym: "down regulation of cell-cell adhesion" EXACT [] synonym: "down-regulation of cell-cell adhesion" EXACT [] synonym: "downregulation of cell-cell adhesion" EXACT [] synonym: "inhibition of cell-cell adhesion" NARROW [] is_a: GO:0007162 ! negative regulation of cell adhesion is_a: GO:0022407 ! regulation of cell-cell adhesion intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0098609 ! cell-cell adhesion relationship: negatively_regulates GO:0098609 ! cell-cell adhesion [Term] id: GO:0022409 name: positive regulation of cell-cell adhesion namespace: biological_process def: "Any process that activates or increases the rate or extent of cell adhesion to another cell." [GOC:isa_complete] synonym: "activation of cell-cell adhesion" NARROW [] synonym: "stimulation of cell-cell adhesion" NARROW [] synonym: "up regulation of cell-cell adhesion" EXACT [] synonym: "up-regulation of cell-cell adhesion" EXACT [] synonym: "upregulation of cell-cell adhesion" EXACT [] is_a: GO:0022407 ! regulation of cell-cell adhesion is_a: GO:0045785 ! positive regulation of cell adhesion intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0098609 ! cell-cell adhesion relationship: positively_regulates GO:0098609 ! cell-cell adhesion [Term] id: GO:0022411 name: cellular component disassembly namespace: biological_process alt_id: GO:0071845 def: "A cellular process that results in the breakdown of a cellular component." [GOC:isa_complete] subset: goslim_pir synonym: "cell structure disassembly" EXACT [] synonym: "cellular component disassembly at cellular level" EXACT [] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0009987 ! cellular process intersection_of: results_in_disassembly_of GO:0005575 ! cellular_component disjoint_from: GO:0022607 ! cellular component assembly relationship: results_in_disassembly_of GO:0005575 ! cellular_component [Term] id: GO:0022412 name: cellular process involved in reproduction in multicellular organism namespace: biological_process def: "A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular organism." [GOC:isa_complete] synonym: "reproductive cellular process in multicellular organism" EXACT [] is_a: GO:0009987 ! cellular process is_a: GO:0022414 ! reproductive process intersection_of: GO:0009987 ! cellular process intersection_of: part_of GO:0032504 ! multicellular organism reproduction relationship: part_of GO:0032504 ! multicellular organism reproduction [Term] id: GO:0022414 name: reproductive process namespace: biological_process alt_id: GO:0044702 def: "A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents." [GOC:dph, GOC:isa_complete] subset: goslim_generic synonym: "single organism reproductive process" RELATED [] is_a: GO:0008150 ! biological process intersection_of: GO:0008150 ! biological process intersection_of: part_of GO:0000003 ! reproduction relationship: part_of GO:0000003 ! reproduction created_by: jl creation_date: 2012-09-19T15:56:06Z [Term] id: GO:0022600 name: digestive system process namespace: biological_process def: "A physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." [GOC:isa_complete, GOC:jid, GOC:mtg_cardio] subset: goslim_generic is_a: GO:0003008 ! system process intersection_of: GO:0003008 ! system process intersection_of: part_of GO:0007586 ! digestion relationship: part_of GO:0007586 ! digestion [Term] id: GO:0022602 name: ovulation cycle process namespace: biological_process def: "A process involved in the sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years." [GOC:isa_complete] synonym: "estrous cycle process" RELATED [] synonym: "menstrual cycle process" RELATED [] is_a: GO:0022414 ! reproductive process is_a: GO:0048511 ! rhythmic process relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0042698 ! ovulation cycle [Term] id: GO:0022603 name: regulation of anatomical structure morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of anatomical structure morphogenesis." [GOC:mah] synonym: "regulation of morphogenesis" EXACT [] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0009653 ! anatomical structure morphogenesis relationship: regulates GO:0009653 ! anatomical structure morphogenesis [Term] id: GO:0022604 name: regulation of cell morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process in which the shape of a cell is generated and organized." [GOC:isa_complete] synonym: "negative regulation of cell shape and cell size" RELATED [GOC:dph, GOC:tb] synonym: "positive regulation of cell shape and cell size" RELATED [GOC:dph, GOC:tb] synonym: "regulation of cell shape and cell size" RELATED [GOC:dph, GOC:tb] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0000902 ! cell morphogenesis relationship: regulates GO:0000902 ! cell morphogenesis [Term] id: GO:0022607 name: cellular component assembly namespace: biological_process alt_id: GO:0071844 def: "The aggregation, arrangement and bonding together of a cellular component." [GOC:isa_complete] subset: goslim_chembl subset: goslim_pir synonym: "cell structure assembly" EXACT [] synonym: "cellular component assembly at cellular level" EXACT [] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0009987 ! cellular process intersection_of: results_in_assembly_of GO:0005575 ! cellular_component relationship: part_of GO:0044085 ! cellular component biogenesis relationship: results_in_assembly_of GO:0005575 ! cellular_component [Term] id: GO:0022612 name: gland morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a gland are generated and organized." [GOC:isa_complete] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002530 ! gland relationship: part_of GO:0048732 ! gland development relationship: results_in_morphogenesis_of UBERON:0002530 ! gland [Term] id: GO:0022613 name: ribonucleoprotein complex biogenesis namespace: biological_process def: "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a complex containing RNA and proteins. Includes the biosynthesis of the constituent RNA and protein molecules, and those macromolecular modifications that are involved in synthesis or assembly of the ribonucleoprotein complex." [GOC:isa_complete, GOC:mah] synonym: "ribonucleoprotein complex biogenesis and assembly" EXACT [GOC:mah] synonym: "RNA-protein complex biogenesis" EXACT [GOC:mah] is_a: GO:0044085 ! cellular component biogenesis [Term] id: GO:0022617 name: extracellular matrix disassembly namespace: biological_process def: "A process that results in the breakdown of the extracellular matrix." [GOC:jid] is_a: GO:0022411 ! cellular component disassembly is_a: GO:0030198 ! extracellular matrix organization intersection_of: GO:0022411 ! cellular component disassembly intersection_of: results_in_disassembly_of GO:0031012 ! extracellular matrix relationship: results_in_disassembly_of GO:0031012 ! extracellular matrix [Term] id: GO:0022618 name: protein-RNA complex assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex." [GOC:jl] subset: goslim_chembl synonym: "ribonucleoprotein complex assembly" EXACT [] synonym: "RNA-protein complex assembly" EXACT [] synonym: "RNP complex assembly" EXACT [] is_a: GO:0065003 ! protein-containing complex assembly is_a: GO:0071826 ! protein-RNA complex organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:1990904 ! ribonucleoprotein complex relationship: part_of GO:0022613 ! ribonucleoprotein complex biogenesis relationship: results_in_assembly_of GO:1990904 ! ribonucleoprotein complex [Term] id: GO:0022804 name: active transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction." [GOC:mtg_transport, ISBN:0815340729] synonym: "active carrier activity" EXACT [] synonym: "carrier activity" EXACT [] synonym: "permease activity" EXACT [] synonym: "pump activity" EXACT [] is_a: GO:0022857 ! transmembrane transporter activity [Term] id: GO:0022853 name: active monoatomic ion transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of an ion from one side of a membrane to the other up the solute's concentration gradient. This is carried out by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction." [GOC:mtg_transport, ISBN:0815340729] synonym: "active ion transmembrane transporter activity" BROAD [] is_a: GO:0015075 ! monoatomic ion transmembrane transporter activity is_a: GO:0022804 ! active transmembrane transporter activity intersection_of: GO:0022804 ! active transmembrane transporter activity intersection_of: has_primary_input CHEBI:24867 ! monoatomic ion property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24479" xsd:anyURI [Term] id: GO:0022857 name: transmembrane transporter activity namespace: molecular_function alt_id: GO:0005386 alt_id: GO:0015563 alt_id: GO:0015646 alt_id: GO:0022891 alt_id: GO:0022892 def: "Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other." [GOC:jid, GOC:mtg_transport, ISBN:0815340729] subset: goslim_chembl subset: goslim_drosophila subset: goslim_yeast synonym: "substrate-specific transmembrane transporter activity" RELATED [] synonym: "substrate-specific transporter activity" RELATED [] synonym: "uptake permease activity" RELATED [] synonym: "uptake transmembrane transporter activity" RELATED [] xref: Reactome:R-HSA-1236947 "Egress of internalized antigen to the cytosol via sec61" xref: Reactome:R-HSA-429036 "SLC2A9 transports Fru, Glc, urate" xref: Reactome:R-HSA-5638209 "Defective SLC2A9 does not transport Fru, Glc, urate" xref: Reactome:R-HSA-5671707 "Fe3+ dissociates from SLC22A17:LCN2:2,5DHBA" xref: Reactome:R-HSA-6784434 "An unknown carrier transports cytosolic glyoxylate to the peroxisome" xref: Reactome:R-HSA-6784436 "An unknown carrier transports mitochondrial glyoxylate to the cytosol" is_a: GO:0005215 ! transporter activity intersection_of: GO:0005215 ! transporter activity intersection_of: results_in_transport_across GO:0016020 ! membrane relationship: part_of GO:0055085 ! transmembrane transport relationship: results_in_transport_across GO:0016020 ! membrane [Term] id: GO:0022884 name: macromolecule transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of a macromolecule from one side of a membrane to the other." [GOC:mtg_transport, ISBN:0815340729] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:33694 ! biomacromolecule relationship: has_primary_input CHEBI:33694 ! biomacromolecule [Term] id: GO:0022890 name: inorganic cation transmembrane transporter activity namespace: molecular_function alt_id: GO:0015077 alt_id: GO:0015082 alt_id: GO:0072509 alt_id: GO:0072510 def: "Enables the transfer of inorganic cations from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] synonym: "di-, tri-valent inorganic cation transmembrane transporter activity" NARROW [GOC:mah] synonym: "divalent inorganic cation transmembrane transporter activity" NARROW [] synonym: "monovalent inorganic cation transmembrane transporter activity" NARROW [] synonym: "trivalent inorganic cation transmembrane transporter activity" NARROW [] is_a: GO:0015318 ! inorganic molecular entity transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:36915 ! inorganic cation relationship: has_primary_input CHEBI:36915 ! inorganic cation [Term] id: GO:0022898 name: regulation of transmembrane transporter activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of transmembrane transporter activity." [GOC:dph, GOC:mtg_cardio, GOC:mtg_transport] subset: gocheck_do_not_annotate is_a: GO:0032409 ! regulation of transporter activity is_a: GO:0034762 ! regulation of transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0022857 ! transmembrane transporter activity relationship: regulates GO:0022857 ! transmembrane transporter activity [Term] id: GO:0023019 name: signal transduction involved in regulation of gene expression namespace: biological_process def: "Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a signal is released and/or conveyed from one location to another." [GOC:mtg_signal] synonym: "regulation of gene expression as a consequence of signal transmission" RELATED [GOC:bf] is_a: GO:0007165 ! signal transduction intersection_of: GO:0007165 ! signal transduction intersection_of: part_of GO:0010468 ! regulation of gene expression relationship: part_of GO:0010468 ! regulation of gene expression creation_date: 2010-02-16T09:30:50Z [Term] id: GO:0023051 name: regulation of signaling namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a signaling process." [GOC:mtg_signal] synonym: "regulation of signaling process" RELATED [GOC:bf] synonym: "regulation of signalling process" RELATED [GOC:mah] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0023052 ! signaling relationship: regulates GO:0023052 ! signaling creation_date: 2010-02-16T09:30:50Z [Term] id: GO:0023052 name: signaling namespace: biological_process alt_id: GO:0023046 alt_id: GO:0044700 def: "The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered." [GOC:mtg_signal, GOC:mtg_signaling_feb11, GOC:signaling] comment: Note that a signal is any variable property or parameter that serves to convey information, and may be a physical entity such as a gene product or small molecule, a photon, or a change in state such as movement or voltage change. subset: goslim_agr subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_mouse subset: goslim_pombe subset: goslim_prokaryote subset: goslim_yeast synonym: "biological signaling" EXACT [] synonym: "signaling process" EXACT [] synonym: "signalling" EXACT [] synonym: "signalling process" RELATED [GOC:mah] synonym: "single organism signaling" RELATED [] is_a: GO:0050789 ! regulation of biological process created_by: jl creation_date: 2010-02-16T09:30:50Z [Term] id: GO:0023056 name: positive regulation of signaling namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of a signaling process." [GOC:mtg_signal] synonym: "positive regulation of signaling process" RELATED [GOC:bf] synonym: "positive regulation of signalling process" EXACT [GOC:mah] is_a: GO:0023051 ! regulation of signaling is_a: GO:0048518 ! positive regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0023052 ! signaling relationship: positively_regulates GO:0023052 ! signaling creation_date: 2010-02-16T09:30:50Z [Term] id: GO:0023057 name: negative regulation of signaling namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a signaling process." [GOC:mtg_signal] synonym: "negative regulation of signaling process" RELATED [GOC:bf] synonym: "negative regulation of signalling process" RELATED [GOC:mah] is_a: GO:0023051 ! regulation of signaling is_a: GO:0048519 ! negative regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0023052 ! signaling relationship: negatively_regulates GO:0023052 ! signaling creation_date: 2010-02-16T09:30:50Z [Term] id: GO:0023061 name: signal release namespace: biological_process def: "The process in which a signal is secreted or discharged into the extracellular medium from a cellular source." [GOC:mtg_signal] synonym: "signal secretion" EXACT [GOC:bf] is_a: GO:0032940 ! secretion by cell intersection_of: GO:0032940 ! secretion by cell intersection_of: part_of GO:0007267 ! cell-cell signaling relationship: part_of GO:0007267 ! cell-cell signaling creation_date: 2010-02-16T09:30:50Z [Term] id: GO:0030001 name: metal ion transport namespace: biological_process alt_id: GO:0070838 alt_id: GO:0070839 def: "The directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "divalent metal ion export" NARROW [] synonym: "divalent metal ion transport" NARROW [] synonym: "heavy metal ion transport" NARROW [] synonym: "metal ion export" NARROW [] is_a: GO:0006812 ! monoatomic cation transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:25213 ! metal cation relationship: has_primary_input CHEBI:25213 ! metal cation property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23033" xsd:anyURI created_by: mah creation_date: 2009-07-31T01:07:46Z [Term] id: GO:0030010 name: establishment of cell polarity namespace: biological_process alt_id: GO:0000283 alt_id: GO:0030468 def: "The specification and formation of anisotropic intracellular organization or cell growth patterns." [GOC:mah] synonym: "bud site selection/establishment of cell polarity" NARROW [] synonym: "cell polarization" EXACT [] is_a: GO:0007163 ! establishment or maintenance of cell polarity [Term] id: GO:0030016 name: myofibril namespace: cellular_component def: "The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism." [ISBN:0815316194] xref: Wikipedia:Myofibril is_a: GO:0043292 ! contractile fiber intersection_of: GO:0043292 ! contractile fiber intersection_of: part_of CL:0000737 ! striated muscle cell relationship: part_of CL:0000737 ! striated muscle cell [Term] id: GO:0030017 name: sarcomere namespace: cellular_component def: "The repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." [ISBN:0815316194] xref: Wikipedia:Sarcomere is_a: GO:0110165 ! cellular anatomical entity is_a: UBERON:0004120 ! mesoderm-derived structure relationship: part_of GO:0030016 ! myofibril [Term] id: GO:0030029 name: actin filament-based process namespace: biological_process def: "Any cellular process that depends upon or alters the actin cytoskeleton, that part of the cytoskeleton comprising actin filaments and their associated proteins." [GOC:mah] synonym: "microfilament-based process" RELATED [] is_a: GO:0009987 ! cellular process intersection_of: GO:0009987 ! cellular process intersection_of: process_has_causal_agent GO:0005884 ! actin filament relationship: process_has_causal_agent GO:0005884 ! actin filament [Term] id: GO:0030030 name: cell projection organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, GOC:mah, http://www.cogsci.princeton.edu/~wn/] subset: goslim_prokaryote synonym: "cell projection organisation" EXACT [] synonym: "cell projection organization and biogenesis" RELATED [GOC:mah] synonym: "cell surface structure organization and biogenesis" RELATED [GOC:mah] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0042995 ! cell projection relationship: results_in_organization_of GO:0042995 ! cell projection property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26279" xsd:anyURI [Term] id: GO:0030031 name: cell projection assembly namespace: biological_process def: "Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, GOC:mah, http://www.cogsci.princeton.edu/~wn/] synonym: "cell projection biogenesis" RELATED [GOC:mah] synonym: "formation of a cell surface projection" EXACT [] is_a: GO:0022607 ! cellular component assembly is_a: GO:0030030 ! cell projection organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0042995 ! cell projection relationship: results_in_assembly_of GO:0042995 ! cell projection [Term] id: GO:0030033 name: microvillus assembly namespace: biological_process def: "Formation of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell." [GOC:mah, ISBN:0815316194] synonym: "microvillus biogenesis" RELATED [GOC:mah] is_a: GO:0032528 ! microvillus organization is_a: GO:0120031 ! plasma membrane bounded cell projection assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0005902 ! microvillus relationship: results_in_assembly_of GO:0005902 ! microvillus [Term] id: GO:0030036 name: actin cytoskeleton organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins." [GOC:dph, GOC:jl, GOC:mah] subset: goslim_pombe synonym: "actin cytoskeleton organisation" EXACT [] synonym: "actin cytoskeleton organization and biogenesis" RELATED [GOC:mah] synonym: "actin modulating activity" RELATED [] is_a: GO:0007010 ! cytoskeleton organization is_a: GO:0030029 ! actin filament-based process intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0015629 ! actin cytoskeleton relationship: results_in_organization_of GO:0015629 ! actin cytoskeleton property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23114" xsd:anyURI [Term] id: GO:0030048 name: actin filament-based movement namespace: biological_process def: "Movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins." [GOC:BHF, GOC:mah] is_a: GO:0030029 ! actin filament-based process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19809" xsd:anyURI [Term] id: GO:0030050 name: vesicle transport along actin filament namespace: biological_process def: "Movement of a vesicle along an actin filament, mediated by motor proteins." [GOC:mah] is_a: GO:0030048 ! actin filament-based movement is_a: GO:0099515 ! actin filament-based transport is_a: GO:0099518 ! vesicle cytoskeletal trafficking intersection_of: GO:0046907 ! intracellular transport intersection_of: has_primary_input GO:0031982 ! vesicle intersection_of: results_in_transport_along GO:0005884 ! actin filament [Term] id: GO:0030054 name: cell junction namespace: cellular_component def: "A cellular component that forms a specialized region of connection between two or more cells, or between a cell and the extracellular matrix, or between two membrane-bound components of a cell, such as flagella." [GOC:aruk, GOC:bc, GOC:mah, http://www.vivo.colostate.edu/hbooks/cmb/cells/pmemb/junctions_a.html, ISBN:0198506732, PMID:26820516, PMID:28096264] subset: goslim_agr subset: goslim_drosophila subset: goslim_flybase_ribbon xref: Wikipedia:Cell_junction is_a: GO:0110165 ! cellular anatomical entity property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0030072 name: peptide hormone secretion namespace: biological_process def: "The regulated release of a peptide hormone from a cell." [GOC:mah] is_a: GO:0002790 ! peptide secretion is_a: GO:0046879 ! hormone secretion intersection_of: GO:0046903 ! secretion intersection_of: has_primary_input CHEBI:25905 ! peptide hormone relationship: has_primary_input CHEBI:25905 ! peptide hormone [Term] id: GO:0030073 name: insulin secretion namespace: biological_process def: "The regulated release of proinsulin from secretory granules accompanied by cleavage of proinsulin to form mature insulin. In vertebrates, insulin is secreted from B granules in the B cells of the vertebrate pancreas and from insulin-producing cells in insects." [GOC:mah, ISBN:0198506732] is_a: GO:0009306 ! protein secretion is_a: GO:0030072 ! peptide hormone secretion intersection_of: GO:0046903 ! secretion intersection_of: has_primary_input PR:000009054 ! insulin gene translation product relationship: has_primary_input PR:000009054 ! insulin gene translation product relationship: in_taxon NCBITaxon:6072 {all_only="true"} ! Eumetazoa relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/11255#issuecomment-426191045" xsd:anyURI [Term] id: GO:0030097 name: hemopoiesis namespace: biological_process def: "The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates." [GOC:dgh, ISBN:0198506732] synonym: "blood cell biosynthesis" EXACT [] synonym: "blood cell formation" EXACT [] synonym: "haemopoiesis" EXACT [] synonym: "hematopoiesis" EXACT [] xref: Wikipedia:Haematopoiesis is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000988 ! hematopoietic cell relationship: results_in_development_of CL:0000988 ! hematopoietic cell property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22178" xsd:anyURI [Term] id: GO:0030098 name: lymphocyte differentiation namespace: biological_process alt_id: GO:0046650 def: "The process in which a relatively unspecialized precursor cell acquires specialized features of a lymphocyte. A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin." [CL:0000542, GOC:go_curators] comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. synonym: "lymphocyte cell differentiation" EXACT [] synonym: "lymphocyte development" RELATED [GOC:add] synonym: "lymphocytic blood cell differentiation" EXACT [] is_a: GO:0046649 ! lymphocyte activation is_a: GO:1903131 ! mononuclear cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000542 ! lymphocyte relationship: results_in_acquisition_of_features_of CL:0000542 ! lymphocyte [Term] id: GO:0030099 name: myeloid cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages." [GOC:add, ISBN:0781735149] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000763 ! myeloid cell relationship: part_of GO:0030097 ! hemopoiesis relationship: results_in_acquisition_of_features_of CL:0000763 ! myeloid cell [Term] id: GO:0030100 name: regulation of endocytosis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of endocytosis." [GOC:go_curators] is_a: GO:0051128 ! regulation of cellular component organization is_a: GO:0060627 ! regulation of vesicle-mediated transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006897 ! endocytosis relationship: regulates GO:0006897 ! endocytosis [Term] id: GO:0030133 name: transport vesicle namespace: cellular_component def: "Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell." [GOC:mah, PMID:22160157] comment: Note that the term 'secretory vesicle' is sometimes used in this sense, but can also mean 'secretory granule ; GO:0030141'. synonym: "constitutive secretory pathway transport vesicle" EXACT [] synonym: "Golgi to vacuole transport vesicle" NARROW [] synonym: "Golgi-vacuole transport vesicle" NARROW [] synonym: "secretory vesicle" RELATED [] xref: NIF_Subcellular:sao885490876 is_a: GO:0031410 ! cytoplasmic vesicle relationship: part_of GO:0012505 ! endomembrane system [Term] id: GO:0030141 name: secretory granule namespace: cellular_component def: "A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules." [GOC:mah, ISBN:0198506732] comment: Note that the term 'secretory vesicle' is sometimes used in this sense, but can also mean 'transport vesicle ; GO:0030133'. synonym: "secretory vesicle" BROAD [] is_a: GO:0099503 ! secretory vesicle relationship: part_of GO:0012505 ! endomembrane system property_value: RO:0002161 NCBITaxon:4890 [Term] id: GO:0030154 name: cell differentiation namespace: biological_process def: "The cellular developmental process in which a relatively unspecialized cell, e.g. embryonic or regenerative cell, acquires specialized structural and/or functional features that characterize a specific cell. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state." [ISBN:0198506732] subset: goslim_agr subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_mouse subset: goslim_plant xref: Wikipedia:Cellular_differentiation is_a: GO:0048869 ! cellular developmental process intersection_of: GO:0048869 ! cellular developmental process intersection_of: results_in_acquisition_of_features_of CL:0000000 ! cell relationship: results_in_acquisition_of_features_of CL:0000000 ! cell property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24390" xsd:anyURI [Term] id: GO:0030155 name: regulation of cell adhesion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix." [GOC:mah] synonym: "cell adhesion receptor regulator activity" RELATED [] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007155 ! cell adhesion relationship: regulates GO:0007155 ! cell adhesion [Term] id: GO:0030163 name: protein catabolic process namespace: biological_process alt_id: GO:0044254 alt_id: GO:0044257 def: "The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds." [GOC:mah] comment: This term refers to the breakdown of mature proteins. For cleavage events involved in generating a mature protein from a precursor, consider instead the term 'protein maturation ; GO:0051604' and its children. subset: goslim_candida subset: goslim_drosophila subset: goslim_generic subset: goslim_pombe subset: goslim_prokaryote synonym: "cellular protein breakdown" EXACT [] synonym: "cellular protein catabolic process" EXACT [] synonym: "cellular protein catabolism" EXACT [] synonym: "cellular protein degradation" EXACT [] synonym: "multicellular organismal protein catabolic process" NARROW [] synonym: "pheromone catabolic process" RELATED [] synonym: "pheromone catabolism" RELATED [] synonym: "protein breakdown" EXACT [] synonym: "protein catabolism" EXACT [] synonym: "protein degradation" EXACT [] xref: Wikipedia:Protein_catabolism is_a: GO:0019538 ! protein metabolic process is_a: GO:1901565 ! organonitrogen compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input PR:000000001 ! protein relationship: has_primary_input PR:000000001 ! protein property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23112" xsd:anyURI [Term] id: GO:0030182 name: neuron differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a neuron." [GOC:mah] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000540 ! neuron relationship: part_of GO:0048699 ! generation of neurons relationship: results_in_acquisition_of_features_of CL:0000540 ! neuron [Term] id: GO:0030198 name: extracellular matrix organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix." [GOC:mah] subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic synonym: "extracellular matrix organisation" EXACT [] synonym: "extracellular matrix organization and biogenesis" RELATED [GOC:mah] is_a: GO:0043062 ! extracellular structure organization is_a: GO:0045229 ! external encapsulating structure organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0031012 ! extracellular matrix relationship: results_in_organization_of GO:0031012 ! extracellular matrix [Term] id: GO:0030199 name: collagen fibril organization namespace: biological_process def: "Any process that determines the size and arrangement of collagen fibrils within an extracellular matrix." [GOC:mah, ISBN:0815316194] synonym: "collagen fibril organisation" EXACT [] synonym: "fibrillar collagen organization" EXACT [GOC:mah] is_a: GO:0030198 ! extracellular matrix organization is_a: GO:0097435 ! supramolecular fiber organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0098643 ! banded collagen fibril relationship: results_in_organization_of GO:0098643 ! banded collagen fibril property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0030203 name: glycosaminoglycan metabolic process namespace: biological_process def: "The chemical reactions and pathways involving glycosaminoglycans, any of a group of polysaccharides that contain amino sugars." [ISBN:0192800981] synonym: "glycosaminoglycan metabolism" EXACT [] is_a: GO:0006022 ! aminoglycan metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:18085 ! glycosaminoglycan relationship: has_primary_input_or_output CHEBI:18085 ! glycosaminoglycan [Term] id: GO:0030212 name: hyaluronan metabolic process namespace: biological_process def: "The chemical reactions and pathways involving hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine." [GOC:mah, ISBN:0198506732] synonym: "hyaluronan metabolism" EXACT [] is_a: GO:1903510 ! mucopolysaccharide metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:16336 ! hyaluronic acid relationship: has_primary_input_or_output CHEBI:16336 ! hyaluronic acid [Term] id: GO:0030213 name: hyaluronan biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine." [GOC:mah, ISBN:0198506732] synonym: "hyaluronan anabolism" EXACT [] synonym: "hyaluronan biosynthesis" EXACT [] synonym: "hyaluronan formation" EXACT [] synonym: "hyaluronan synthesis" EXACT [] is_a: GO:0006024 ! glycosaminoglycan biosynthetic process is_a: GO:0030212 ! hyaluronan metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:16336 ! hyaluronic acid relationship: has_primary_output CHEBI:16336 ! hyaluronic acid [Term] id: GO:0030214 name: hyaluronan catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine." [GOC:mah, ISBN:0198506732] synonym: "hyaluronan breakdown" EXACT [] synonym: "hyaluronan catabolism" EXACT [] synonym: "hyaluronan degradation" EXACT [] is_a: GO:0006027 ! glycosaminoglycan catabolic process is_a: GO:0030212 ! hyaluronan metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:16336 ! hyaluronic acid relationship: has_primary_input CHEBI:16336 ! hyaluronic acid [Term] id: GO:0030217 name: T cell differentiation namespace: biological_process alt_id: GO:0042112 alt_id: GO:0046652 def: "The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex." [GO_REF:0000022, GOC:jid, GOC:mah] comment: Note that the term 'thymocyte differentiation' was merged into this term because thymocytes are T cells, and thus the term was essentially redundant. Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. synonym: "T cell development" RELATED [GOC:add] synonym: "T lymphocyte differentiation" EXACT [] synonym: "T-cell differentiation" EXACT [] synonym: "T-lymphocyte differentiation" EXACT [] is_a: GO:0030098 ! lymphocyte differentiation is_a: GO:0042110 ! T cell activation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000084 ! T cell relationship: results_in_acquisition_of_features_of CL:0000084 ! T cell [Term] id: GO:0030218 name: erythrocyte differentiation namespace: biological_process def: "The process in which a myeloid precursor cell acquires specializes features of an erythrocyte." [GOC:mah] synonym: "erythrocyte cell differentiation" EXACT [] synonym: "erythropoiesis" EXACT [GOC:add, GOC:dph] synonym: "RBC differentiation" EXACT [CL:0000232] synonym: "red blood cell differentiation" EXACT [CL:0000232] xref: Wikipedia:Erythropoiesis is_a: GO:0030099 ! myeloid cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000232 ! erythrocyte relationship: part_of GO:0034101 ! erythrocyte homeostasis relationship: results_in_acquisition_of_features_of CL:0000232 ! erythrocyte [Term] id: GO:0030219 name: megakaryocyte differentiation namespace: biological_process def: "The process in which a myeloid precursor cell acquires specializes features of a megakaryocyte." [GOC:mah] synonym: "megakaryocyte cell differentiation" EXACT [] is_a: GO:0030099 ! myeloid cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000556 ! megakaryocyte relationship: results_in_acquisition_of_features_of CL:0000556 ! megakaryocyte [Term] id: GO:0030239 name: myofibril assembly namespace: biological_process def: "Formation of myofibrils, the repeating units of striated muscle." [GOC:mah] is_a: GO:0010927 ! cellular component assembly involved in morphogenesis is_a: GO:0031032 ! actomyosin structure organization is_a: GO:0097435 ! supramolecular fiber organization is_a: GO:0140694 ! non-membrane-bounded organelle assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0030016 ! myofibril relationship: part_of GO:0055002 ! striated muscle cell development relationship: results_in_assembly_of GO:0030016 ! myofibril [Term] id: GO:0030261 name: chromosome condensation namespace: biological_process alt_id: GO:0000068 def: "The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells." [GOC:mah, ISBN:0815316194] synonym: "DNA condensation" BROAD [Wikipedia:DNA_condensation] synonym: "eukaryotic chromosome condensation" EXACT [GOC:bf] synonym: "nuclear chromosome condensation" EXACT [GOC:bf] is_a: GO:0051276 ! chromosome organization [Term] id: GO:0030262 name: apoptotic nuclear changes namespace: biological_process def: "Alterations undergone by nuclei at the molecular and morphological level as part of the execution phase of apoptosis." [GOC:mah, GOC:mtg_apoptosis] synonym: "apoptotic nuclear change" NARROW [] is_a: GO:0006921 ! cellular component disassembly involved in execution phase of apoptosis [Term] id: GO:0030263 name: apoptotic chromosome condensation namespace: biological_process def: "The compaction of chromatin during apoptosis." [GOC:mah] synonym: "pyknosis" EXACT [] xref: Wikipedia:Pyknosis is_a: GO:0030261 ! chromosome condensation relationship: part_of GO:0030262 ! apoptotic nuclear changes [Term] id: GO:0030264 name: nuclear fragmentation involved in apoptotic nuclear change namespace: biological_process def: "The breakdown of the nucleus into small membrane-bounded compartments, or blebs, each of which contain compacted DNA." [GOC:dph, GOC:mah, GOC:mtg_apoptosis, GOC:tb, ISBN:0721639976] synonym: "apoptotic nuclear fragmentation" EXACT [] synonym: "nuclear fragmentation during apoptosis" RELATED [GOC:dph, GOC:tb] synonym: "nucleus fragmentation" EXACT [] is_a: GO:0071763 ! nuclear membrane organization intersection_of: GO:0071763 ! nuclear membrane organization intersection_of: part_of GO:0030262 ! apoptotic nuclear changes relationship: part_of GO:0030262 ! apoptotic nuclear changes [Term] id: GO:0030278 name: regulation of ossification namespace: biological_process def: "Any process that modulates the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance." [GOC:go_curators] synonym: "regulation of bone biosynthesis" EXACT [] synonym: "regulation of bone formation" EXACT [] is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001503 ! ossification relationship: regulates GO:0001503 ! ossification [Term] id: GO:0030279 name: negative regulation of ossification namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance." [GOC:go_curators] synonym: "down regulation of ossification" EXACT [] synonym: "down-regulation of ossification" EXACT [] synonym: "downregulation of ossification" EXACT [] synonym: "inhibition of ossification" NARROW [] synonym: "negative regulation of bone biosynthesis" EXACT [] synonym: "negative regulation of bone formation" EXACT [] is_a: GO:0030278 ! regulation of ossification is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001503 ! ossification relationship: negatively_regulates GO:0001503 ! ossification [Term] id: GO:0030307 name: positive regulation of cell growth namespace: biological_process def: "Any process that activates or increases the frequency, rate, extent or direction of cell growth." [GOC:go_curators] synonym: "activation of cell growth" NARROW [] synonym: "stimulation of cell growth" NARROW [] synonym: "up regulation of cell growth" EXACT [] synonym: "up-regulation of cell growth" EXACT [] synonym: "upregulation of cell growth" EXACT [] is_a: GO:0001558 ! regulation of cell growth is_a: GO:0045927 ! positive regulation of growth is_a: GO:0048522 ! positive regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0016049 ! cell growth relationship: positively_regulates GO:0016049 ! cell growth [Term] id: GO:0030308 name: negative regulation of cell growth namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth." [GOC:go_curators] synonym: "down regulation of cell growth" EXACT [] synonym: "down-regulation of cell growth" EXACT [] synonym: "downregulation of cell growth" EXACT [] synonym: "inhibition of cell growth" NARROW [] is_a: GO:0001558 ! regulation of cell growth is_a: GO:0045926 ! negative regulation of growth is_a: GO:0048523 ! negative regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0016049 ! cell growth relationship: negatively_regulates GO:0016049 ! cell growth [Term] id: GO:0030312 name: external encapsulating structure namespace: cellular_component def: "A structure that lies outside the plasma membrane and surrounds the entire cell or cells. This does not include the periplasmic space." [GOC:go_curators] comment: The outer membrane (of gram negative bacteria) or cell wall (of yeast or Gram positive bacteria) are defined as parts of this structure, see 'external encapsulating structure part'. subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_pir subset: goslim_plant is_a: GO:0110165 ! cellular anatomical entity relationship: part_of CL:0000000 ! cell relationship: part_of GO:0071944 ! cell periphery [Term] id: GO:0030317 name: flagellated sperm motility namespace: biological_process alt_id: GO:0097724 alt_id: GO:1905419 def: "The directed, self-propelled movement of a cilium (aka flagellum) that contributes to the movement of a flagellated sperm." [GO_REF:0000060, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:26680031] synonym: "flagellated sperm movement" EXACT [] synonym: "sperm flagellum movement" EXACT [GOC:cilia, GOC:krc] synonym: "sperm flagellum movement involved in flagellated sperm motility" EXACT [] synonym: "sperm flagellum movement involved in flagellated sperm movement" EXACT [GOC:TermGenie] synonym: "sperm motility" BROAD [] synonym: "sperm movement" BROAD [] xref: Wikipedia:Sperm_motility is_a: GO:0060285 ! cilium-dependent cell motility is_a: GO:0060294 ! cilium movement involved in cell motility is_a: GO:0097722 ! sperm motility intersection_of: GO:0060285 ! cilium-dependent cell motility intersection_of: results_in_movement_of CL:0000019 ! sperm [Term] id: GO:0030323 name: respiratory tube development namespace: biological_process def: "The process whose specific outcome is the progression of the respiratory tube over time, from its formation to the mature structure. The respiratory tube is assumed to mean any tube in the respiratory tract." [GOC:jid] is_a: GO:0035295 ! tube development is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000117 ! respiratory tube relationship: results_in_development_of UBERON:0000117 ! respiratory tube [Term] id: GO:0030324 name: lung development namespace: biological_process def: "The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax." [GOC:jid, UBERON:0002048] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002048 ! lung relationship: part_of GO:0030323 ! respiratory tube development relationship: part_of GO:0060541 ! respiratory system development relationship: results_in_development_of UBERON:0002048 ! lung [Term] id: GO:0030334 name: regulation of cell migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell migration." [GOC:go_curators] is_a: GO:2000145 ! regulation of cell motility intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0016477 ! cell migration relationship: regulates GO:0016477 ! cell migration property_value: RO:0002161 NCBITaxon:4890 [Term] id: GO:0030335 name: positive regulation of cell migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell migration." [GOC:go_curators] synonym: "activation of cell migration" NARROW [] synonym: "stimulation of cell migration" NARROW [] synonym: "up regulation of cell migration" EXACT [] synonym: "up-regulation of cell migration" EXACT [] synonym: "upregulation of cell migration" EXACT [] is_a: GO:0030334 ! regulation of cell migration is_a: GO:2000147 ! positive regulation of cell motility intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0016477 ! cell migration relationship: positively_regulates GO:0016477 ! cell migration [Term] id: GO:0030336 name: negative regulation of cell migration namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration." [GOC:go_curators] synonym: "down regulation of cell migration" EXACT [] synonym: "down-regulation of cell migration" EXACT [] synonym: "downregulation of cell migration" EXACT [] synonym: "inhibition of cell migration" NARROW [] is_a: GO:0030334 ! regulation of cell migration is_a: GO:2000146 ! negative regulation of cell motility intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0016477 ! cell migration relationship: negatively_regulates GO:0016477 ! cell migration [Term] id: GO:0030397 name: membrane disassembly namespace: biological_process def: "The controlled breakdown of any cell membrane in the context of a normal process such as autophagy." [GOC:mah] synonym: "membrane breakdown" EXACT [] synonym: "membrane catabolism" EXACT [] synonym: "membrane degradation" EXACT [] is_a: GO:0022411 ! cellular component disassembly is_a: GO:0061024 ! membrane organization intersection_of: GO:0022411 ! cellular component disassembly intersection_of: results_in_disassembly_of GO:0016020 ! membrane relationship: results_in_disassembly_of GO:0016020 ! membrane [Term] id: GO:0030421 name: defecation namespace: biological_process def: "The expulsion of feces from the rectum." [GOC:mah] xref: Wikipedia:Defecation is_a: GO:0007588 ! excretion is_a: GO:0022600 ! digestive system process [Term] id: GO:0030432 name: peristalsis namespace: biological_process def: "A wavelike sequence of involuntary muscular contraction and relaxation that passes along a tubelike structure, such as the intestine, impelling the contents onwards." [ISBN:0198506732] xref: Wikipedia:Peristalsis is_a: GO:0014821 ! phasic smooth muscle contraction [Term] id: GO:0030473 name: nuclear migration along microtubule namespace: biological_process alt_id: GO:0000065 def: "The directed movement of the nucleus along microtubules within the cell, mediated by motor proteins." [GOC:mah, GOC:sgd_curators] synonym: "microtubule cytoskeleton-dependent nuclear positioning" EXACT [] synonym: "microtubule cytoskeleton-dependent nucleus positioning" EXACT [] synonym: "microtubule-dependent nuclear positioning" EXACT [] synonym: "microtubule-dependent nucleus positioning" EXACT [] synonym: "microtubule-mediated nuclear migration" EXACT [] synonym: "nuclear migration, microtubule-mediated" EXACT [] synonym: "nuclear movement, microtubule-mediated" BROAD [] synonym: "nucleus migration" BROAD [] synonym: "transport of nucleus by microtubules" EXACT [] synonym: "transport of nucleus, microtubule-mediated" EXACT [] is_a: GO:0007097 ! nuclear migration is_a: GO:0072384 ! organelle transport along microtubule intersection_of: GO:0007097 ! nuclear migration intersection_of: results_in_transport_along GO:0015630 ! microtubule cytoskeleton relationship: results_in_transport_along GO:0015630 ! microtubule cytoskeleton [Term] id: GO:0030485 name: smooth muscle contractile fiber namespace: cellular_component def: "The contractile fiber of smooth muscle cells." [GOC:mah] is_a: GO:0043292 ! contractile fiber intersection_of: GO:0043292 ! contractile fiber intersection_of: part_of CL:0000192 ! smooth muscle cell relationship: part_of CL:0000192 ! smooth muscle cell [Term] id: GO:0030539 name: male genitalia development namespace: biological_process def: "The process whose specific outcome is the progression of the male genitalia over time, from its formation to the mature structure." [GOC:ems, ISBN:0140512888] synonym: "male genital development" EXACT [] is_a: GO:0048806 ! genitalia development is_a: GO:0061458 ! reproductive system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000079 ! male reproductive system relationship: part_of GO:0046661 ! male sex differentiation relationship: results_in_development_of UBERON:0000079 ! male reproductive system [Term] id: GO:0030573 name: bile acid catabolic process namespace: biological_process alt_id: GO:0019613 def: "The chemical reactions and pathways resulting in the breakdown of bile acids, any of a group of steroid carboxylic acids occurring in bile." [GOC:go_curators] synonym: "bile acid 7alpha-dehydroxylation pathway" NARROW [] synonym: "bile acid breakdown" EXACT [] synonym: "bile acid catabolism" EXACT [] synonym: "bile acid degradation" EXACT [] synonym: "cholate catabolic process" NARROW [] is_a: GO:0008206 ! bile acid metabolic process is_a: GO:0072329 ! monocarboxylic acid catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:36235 ! bile acid anion relationship: has_primary_input CHEBI:36235 ! bile acid anion [Term] id: GO:0030574 name: collagen catabolic process namespace: biological_process def: "The proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix, usually carried out by proteases secreted by nearby cells." [GOC:mah, ISBN:0815316194] synonym: "collagen breakdown" EXACT [] synonym: "collagen catabolism" EXACT [] synonym: "collagen degradation" EXACT [] is_a: GO:0009056 ! catabolic process is_a: GO:0032963 ! collagen metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input GO:0005581 ! collagen trimer relationship: has_primary_input GO:0005581 ! collagen trimer [Term] id: GO:0030658 name: transport vesicle membrane namespace: cellular_component def: "The lipid bilayer surrounding a transport vesicle." [GOC:mah] synonym: "constitutive secretory pathway transport vesicle membrane" EXACT [] synonym: "secretory vesicle membrane" BROAD [] is_a: GO:0030659 ! cytoplasmic vesicle membrane is_a: GO:0098588 ! bounding membrane of organelle intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0030133 ! transport vesicle relationship: bounding_layer_of GO:0030133 ! transport vesicle relationship: part_of GO:0030133 ! transport vesicle [Term] id: GO:0030659 name: cytoplasmic vesicle membrane namespace: cellular_component def: "The lipid bilayer surrounding a cytoplasmic vesicle." [GOC:mah] is_a: GO:0012506 ! vesicle membrane intersection_of: GO:0016020 ! membrane intersection_of: part_of GO:0031410 ! cytoplasmic vesicle relationship: part_of GO:0031410 ! cytoplasmic vesicle [Term] id: GO:0030660 name: Golgi-associated vesicle membrane namespace: cellular_component def: "The lipid bilayer surrounding a vesicle associated with the Golgi apparatus." [GOC:mah] synonym: "Golgi vesicle membrane" RELATED [] is_a: GO:0030659 ! cytoplasmic vesicle membrane is_a: GO:0098588 ! bounding membrane of organelle intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0005798 ! Golgi-associated vesicle relationship: bounding_layer_of GO:0005798 ! Golgi-associated vesicle relationship: part_of GO:0005798 ! Golgi-associated vesicle [Term] id: GO:0030667 name: secretory granule membrane namespace: cellular_component def: "The lipid bilayer surrounding a secretory granule." [GOC:mah] synonym: "secretory vesicle membrane" BROAD [] is_a: GO:0030659 ! cytoplasmic vesicle membrane is_a: GO:0098588 ! bounding membrane of organelle intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0030141 ! secretory granule relationship: bounding_layer_of GO:0030141 ! secretory granule relationship: part_of GO:0030141 ! secretory granule [Term] id: GO:0030705 name: cytoskeleton-dependent intracellular transport namespace: biological_process def: "The directed movement of substances along cytoskeletal fibers such as microfilaments or microtubules within a cell." [GOC:mah] subset: goslim_chembl subset: goslim_drosophila is_a: GO:0046907 ! intracellular transport intersection_of: GO:0046907 ! intracellular transport intersection_of: results_in_transport_along GO:0099513 ! polymeric cytoskeletal fiber relationship: results_in_transport_along GO:0099513 ! polymeric cytoskeletal fiber [Term] id: GO:0030718 name: germ-line stem cell population maintenance namespace: biological_process def: "Any process by which an organism or tissue maintains a population of germ-line stem cells." [ISBN:0879694238] is_a: GO:0019827 ! stem cell population maintenance intersection_of: GO:0098727 ! maintenance of cell number intersection_of: acts_on_population_of CL:0000014 ! germ line stem cell relationship: acts_on_population_of CL:0000014 ! germ line stem cell [Term] id: GO:0030720 name: oocyte localization involved in germarium-derived egg chamber formation namespace: biological_process def: "Directed movement of the oocyte, following its specification, from its original central position in the cyst to a posterior position relative to the nurse cells of the egg chamber, and its maintenance in this posterior location. This is the first sign of anterior-posterior asymmetry in the developing egg chamber." [GOC:mtg_sensu, PMID:10449356] synonym: "establishment and maintenance of oocyte localization in egg chamber" EXACT [] synonym: "establishment and maintenance of oocyte position during oogenesis" EXACT [] synonym: "oocyte localisation involved in germarium-derived egg chamber formation" EXACT [GOC:mah] synonym: "oocyte localization during germarium-derived egg chamber formation" RELATED [GOC:dph, GOC:tb] synonym: "oocyte localization during oogenesis" RELATED [] synonym: "oocyte positioning during oogenesis" NARROW [] synonym: "oogenesis, establishment and maintenance of oocyte localization" EXACT [] synonym: "oogenesis, oocyte localization" EXACT [] is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0051674 ! localization of cell intersection_of: GO:0051179 ! localization intersection_of: has_primary_input CL:0000023 ! oocyte relationship: has_primary_input CL:0000023 ! oocyte relationship: in_taxon NCBITaxon:50557 {all_only="true"} ! Insecta relationship: only_in_taxon NCBITaxon:50557 ! Insecta relationship: part_of GO:0007293 ! germarium-derived egg chamber formation [Term] id: GO:0030855 name: epithelial cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium." [GOC:ecd, PMID:11839751] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000066 ! epithelial cell relationship: part_of GO:0060429 ! epithelium development relationship: results_in_acquisition_of_features_of CL:0000066 ! epithelial cell [Term] id: GO:0030856 name: regulation of epithelial cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of epithelial cell differentiation." [GOC:mah] is_a: GO:0045595 ! regulation of cell differentiation is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030855 ! epithelial cell differentiation relationship: regulates GO:0030855 ! epithelial cell differentiation [Term] id: GO:0030857 name: negative regulation of epithelial cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell differentiation." [GOC:mah] synonym: "down regulation of epithelial cell differentiation" EXACT [] synonym: "down-regulation of epithelial cell differentiation" EXACT [] synonym: "downregulation of epithelial cell differentiation" EXACT [] synonym: "inhibition of epithelial cell differentiation" NARROW [] is_a: GO:0030856 ! regulation of epithelial cell differentiation is_a: GO:0045596 ! negative regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030855 ! epithelial cell differentiation relationship: negatively_regulates GO:0030855 ! epithelial cell differentiation [Term] id: GO:0030858 name: positive regulation of epithelial cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation." [GOC:mah] synonym: "activation of epithelial cell differentiation" NARROW [] synonym: "stimulation of epithelial cell differentiation" NARROW [] synonym: "up regulation of epithelial cell differentiation" EXACT [] synonym: "up-regulation of epithelial cell differentiation" EXACT [] synonym: "upregulation of epithelial cell differentiation" EXACT [] is_a: GO:0030856 ! regulation of epithelial cell differentiation is_a: GO:0045597 ! positive regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030855 ! epithelial cell differentiation relationship: positively_regulates GO:0030855 ! epithelial cell differentiation [Term] id: GO:0030901 name: midbrain development namespace: biological_process def: "The process whose specific outcome is the progression of the midbrain over time, from its formation to the mature structure. The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles)." [http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=midbrain] synonym: "mesencephalon development" EXACT [] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001891 ! midbrain relationship: part_of GO:0007420 ! brain development relationship: results_in_development_of UBERON:0001891 ! midbrain [Term] id: GO:0030902 name: hindbrain development namespace: biological_process def: "The process whose specific outcome is the progression of the hindbrain over time, from its formation to the mature structure. The hindbrain is the posterior of the three primary divisions of the developing chordate brain, or the corresponding part of the adult brain (in vertebrates, includes the cerebellum, pons, and medulla oblongata and controls the autonomic functions and equilibrium)." [http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=hindbrain] synonym: "rhombencephalon development" EXACT [] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002028 ! hindbrain relationship: part_of GO:0007420 ! brain development relationship: results_in_development_of UBERON:0002028 ! hindbrain [Term] id: GO:0030903 name: notochord development namespace: biological_process def: "The process whose specific outcome is the progression of the notochord over time, from its formation to the mature structure. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column." [GOC:dgh] is_a: GO:0048568 ! embryonic organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002328 ! notochord relationship: results_in_development_of UBERON:0002328 ! notochord [Term] id: GO:0030917 name: midbrain-hindbrain boundary development namespace: biological_process def: "The process whose specific outcome is the progression of the midbrain-hindbrain boundary over time, from its formation to the mature structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages." [GOC:dgh] synonym: "isthmic organizer development" EXACT [] synonym: "isthmomesencephalic boundary development" EXACT [] synonym: "isthmus development" EXACT [] synonym: "MHB development" EXACT [] synonym: "midbrain-hindbrain orgainizer development" EXACT [] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003052 ! midbrain-hindbrain boundary relationship: part_of GO:0007420 ! brain development relationship: part_of GO:0021903 ! rostrocaudal neural tube patterning relationship: results_in_development_of UBERON:0003052 ! midbrain-hindbrain boundary [Term] id: GO:0030936 name: transmembrane collagen trimer namespace: cellular_component def: "Any collagen trimer that passes through a lipid bilayer membrane." [ISBN:0721639976] synonym: "MACIT" EXACT [ISBN:0198599587] is_a: GO:0005581 ! collagen trimer is_a: GO:0098797 ! plasma membrane protein complex intersection_of: GO:0005581 ! collagen trimer intersection_of: part_of GO:0005886 ! plasma membrane [Term] id: GO:0030951 name: establishment or maintenance of microtubule cytoskeleton polarity namespace: biological_process def: "Any cellular process that results in the specification, formation or maintenance of polarized microtubule-based cytoskeletal structures." [GOC:mah] is_a: GO:0000226 ! microtubule cytoskeleton organization is_a: GO:0030952 ! establishment or maintenance of cytoskeleton polarity [Term] id: GO:0030952 name: establishment or maintenance of cytoskeleton polarity namespace: biological_process def: "Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures." [GOC:mah] synonym: "cytoskeleton polarization" RELATED [] is_a: GO:0007010 ! cytoskeleton organization is_a: GO:0007163 ! establishment or maintenance of cell polarity [Term] id: GO:0030990 name: intraciliary transport particle namespace: cellular_component def: "A nonmembrane-bound oligomeric protein complex that participates in bidirectional transport of molecules (cargo) along axonemal microtubules." [GOC:cilia, GOC:kmv, PMID:14570576, PMID:22118932, PMID:23945166] comment: Note that we deem cilia and microtubule-based flagella to be equivalent. subset: goslim_pir synonym: "IFT complex" RELATED [] synonym: "intraflagellar transport complex" EXACT [] synonym: "intraflagellar transport particle" EXACT [] is_a: GO:0032991 ! protein-containing complex relationship: capable_of_part_of GO:0035735 ! intraciliary transport involved in cilium assembly [Term] id: GO:0031012 name: extracellular matrix namespace: cellular_component alt_id: GO:0005578 def: "A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues." [GOC:BHF, GOC:mah, GOC:rph, NIF_Subcellular:nlx_subcell_20090513, PMID:21123617, PMID:28089324] subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_pir subset: goslim_prokaryote synonym: "matrisome" NARROW [] synonym: "proteinaceous extracellular matrix" EXACT [] xref: NIF_Subcellular:nlx_subcell_20090513 xref: Wikipedia:Extracellular_matrix is_a: GO:0030312 ! external encapsulating structure disjoint_from: GO:0032991 ! protein-containing complex disjoint_from: GO:0043226 ! organelle [Term] id: GO:0031016 name: pancreas development namespace: biological_process def: "The process whose specific outcome is the progression of the pancreas over time, from its formation to the mature structure. The pancreas is an endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating hormones." [GOC:cvs] xref: Wikipedia:Pancreas is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001264 ! pancreas relationship: results_in_development_of UBERON:0001264 ! pancreas property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23777" xsd:anyURI [Term] id: GO:0031017 name: exocrine pancreas development namespace: biological_process def: "The process whose specific outcome is the progression of the exocrine pancreas over time, from its formation to the mature structure. The exocrine pancreas produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells." [GOC:cvs] is_a: GO:0048732 ! gland development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000017 ! exocrine pancreas relationship: part_of GO:0031016 ! pancreas development relationship: part_of GO:0035272 ! exocrine system development relationship: part_of GO:0055123 ! digestive system development relationship: results_in_development_of UBERON:0000017 ! exocrine pancreas [Term] id: GO:0031018 name: endocrine pancreas development namespace: biological_process def: "The process whose specific outcome is the progression of the endocrine pancreas over time, from its formation to the mature structure. The endocrine pancreas is made up of islet cells that produce insulin, glucagon and somatostatin." [GOC:cvs] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000016 ! endocrine pancreas relationship: part_of GO:0031016 ! pancreas development relationship: part_of GO:0035270 ! endocrine system development relationship: results_in_development_of UBERON:0000016 ! endocrine pancreas [Term] id: GO:0031022 name: nuclear migration along microfilament namespace: biological_process def: "The directed movement of the nucleus along microfilaments within the cell, mediated by motor proteins." [GOC:mah] synonym: "nuclear migration, microfilament-mediated" EXACT [] is_a: GO:0007097 ! nuclear migration is_a: GO:0030048 ! actin filament-based movement is_a: GO:0099515 ! actin filament-based transport intersection_of: GO:0007097 ! nuclear migration intersection_of: results_in_transport_along GO:0005884 ! actin filament [Term] id: GO:0031032 name: actomyosin structure organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin. The myosin may be organized into filaments." [GOC:dph, GOC:jl, GOC:mah] comment: Note that this term is a child of 'actin cytoskeleton organization and biogenesis ; GO:0030036' because the actin cytoskeleton is defined as actin filaments and associated proteins. synonym: "actomyosin organization" EXACT [] synonym: "actomyosin structure organisation" EXACT [] synonym: "actomyosin structure organization and biogenesis" RELATED [GOC:mah] is_a: GO:0030036 ! actin cytoskeleton organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0042641 ! actomyosin relationship: results_in_organization_of GO:0042641 ! actomyosin [Term] id: GO:0031045 name: dense core granule namespace: cellular_component def: "Electron-dense organelle with a granular internal matrix; contains proteins destined to be secreted." [NIF_Subcellular:sao772007592, PMID:14690495] synonym: "dense core vesicle" EXACT syngo_official_label [GOC:kmv] xref: NIF_Subcellular:sao772007592 is_a: GO:0030141 ! secretory granule [Term] id: GO:0031076 name: embryonic camera-type eye development namespace: biological_process def: "The process occurring during the embryonic phase whose specific outcome is the progression of the eye over time, from its formation to the mature structure." [GOC:mah, GOC:mtg_sensu] synonym: "embryonic eye development" EXACT [] is_a: GO:0043010 ! camera-type eye development is_a: GO:0048568 ! embryonic organ development [Term] id: GO:0031090 name: organelle membrane namespace: cellular_component def: "A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle." [GOC:dos, GOC:mah] synonym: "intracellular membrane" RELATED [NIF_Subcellular:sao830981606] xref: NIF_Subcellular:sao830981606 is_a: GO:0016020 ! membrane intersection_of: GO:0016020 ! membrane intersection_of: part_of GO:0043227 ! membrane-bounded organelle relationship: part_of GO:0043227 ! membrane-bounded organelle [Term] id: GO:0031109 name: microtubule polymerization or depolymerization namespace: biological_process def: "Assembly or disassembly of microtubules by the addition or removal of tubulin heterodimers from a microtubule." [GOC:mah] synonym: "microtubule dynamics" EXACT [] is_a: GO:0000226 ! microtubule cytoskeleton organization property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23195" xsd:anyURI [Term] id: GO:0031110 name: regulation of microtubule polymerization or depolymerization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of microtubule polymerization or depolymerization by the addition or removal of tubulin heterodimers from a microtubule." [GOC:mah] is_a: GO:0070507 ! regulation of microtubule cytoskeleton organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0031109 ! microtubule polymerization or depolymerization relationship: regulates GO:0031109 ! microtubule polymerization or depolymerization [Term] id: GO:0031111 name: negative regulation of microtubule polymerization or depolymerization namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization or depolymerization." [GOC:mah] synonym: "down regulation of microtubule polymerization or depolymerization" EXACT [] synonym: "down-regulation of microtubule polymerization or depolymerization" EXACT [] synonym: "downregulation of microtubule polymerization or depolymerization" EXACT [] synonym: "inhibition of microtubule polymerization or depolymerization" NARROW [] is_a: GO:0031110 ! regulation of microtubule polymerization or depolymerization is_a: GO:0051494 ! negative regulation of cytoskeleton organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0031109 ! microtubule polymerization or depolymerization relationship: negatively_regulates GO:0031109 ! microtubule polymerization or depolymerization [Term] id: GO:0031112 name: positive regulation of microtubule polymerization or depolymerization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of microtubule polymerization or depolymerization." [GOC:mah] synonym: "activation of microtubule polymerization or depolymerization" NARROW [] synonym: "stimulation of microtubule polymerization or depolymerization" NARROW [] synonym: "up regulation of microtubule polymerization or depolymerization" EXACT [] synonym: "up-regulation of microtubule polymerization or depolymerization" EXACT [] synonym: "upregulation of microtubule polymerization or depolymerization" EXACT [] is_a: GO:0031110 ! regulation of microtubule polymerization or depolymerization is_a: GO:0051495 ! positive regulation of cytoskeleton organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0031109 ! microtubule polymerization or depolymerization relationship: positively_regulates GO:0031109 ! microtubule polymerization or depolymerization [Term] id: GO:0031113 name: regulation of microtubule polymerization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of microtubule polymerization." [GOC:mah] is_a: GO:0031110 ! regulation of microtubule polymerization or depolymerization is_a: GO:0032271 ! regulation of protein polymerization is_a: GO:1902903 ! regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0046785 ! microtubule polymerization relationship: regulates GO:0046785 ! microtubule polymerization [Term] id: GO:0031114 name: regulation of microtubule depolymerization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of microtubule depolymerization." [GOC:mah] synonym: "regulation of microtubule disassembly" EXACT [] is_a: GO:0031110 ! regulation of microtubule polymerization or depolymerization is_a: GO:1901879 ! regulation of protein depolymerization is_a: GO:1902903 ! regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007019 ! microtubule depolymerization relationship: regulates GO:0007019 ! microtubule depolymerization [Term] id: GO:0031115 name: negative regulation of microtubule polymerization namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization." [GOC:mah] synonym: "down regulation of microtubule polymerization" EXACT [] synonym: "down-regulation of microtubule polymerization" EXACT [] synonym: "downregulation of microtubule polymerization" EXACT [] synonym: "inhibition of microtubule polymerization" NARROW [] is_a: GO:0031111 ! negative regulation of microtubule polymerization or depolymerization is_a: GO:0031113 ! regulation of microtubule polymerization is_a: GO:0032272 ! negative regulation of protein polymerization is_a: GO:1902904 ! negative regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0046785 ! microtubule polymerization relationship: negatively_regulates GO:0046785 ! microtubule polymerization [Term] id: GO:0031116 name: positive regulation of microtubule polymerization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of microtubule polymerization." [GOC:mah] synonym: "activation of microtubule polymerization" NARROW [] synonym: "stimulation of microtubule polymerization" NARROW [] synonym: "up regulation of microtubule polymerization" EXACT [] synonym: "up-regulation of microtubule polymerization" EXACT [] synonym: "upregulation of microtubule polymerization" EXACT [] is_a: GO:0031112 ! positive regulation of microtubule polymerization or depolymerization is_a: GO:0031113 ! regulation of microtubule polymerization is_a: GO:0032273 ! positive regulation of protein polymerization is_a: GO:1902905 ! positive regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0046785 ! microtubule polymerization relationship: positively_regulates GO:0046785 ! microtubule polymerization [Term] id: GO:0031117 name: positive regulation of microtubule depolymerization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of microtubule depolymerization." [GOC:mah] synonym: "activation of microtubule depolymerization" NARROW [] synonym: "microtubule destabilization" EXACT [] synonym: "positive regulation of microtubule catastrophe" NARROW [GOC:dph, GOC:tb] synonym: "positive regulation of microtubule disassembly" EXACT [] synonym: "stimulation of microtubule depolymerization" NARROW [] synonym: "up regulation of microtubule depolymerization" EXACT [] synonym: "up-regulation of microtubule depolymerization" EXACT [] synonym: "upregulation of microtubule depolymerization" EXACT [] is_a: GO:0031112 ! positive regulation of microtubule polymerization or depolymerization is_a: GO:0031114 ! regulation of microtubule depolymerization is_a: GO:1901881 ! positive regulation of protein depolymerization is_a: GO:1902905 ! positive regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007019 ! microtubule depolymerization relationship: positively_regulates GO:0007019 ! microtubule depolymerization [Term] id: GO:0031122 name: cytoplasmic microtubule organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell." [GOC:mah] synonym: "cytoplasmic microtubule organisation" EXACT [] synonym: "cytoplasmic microtubule organization and biogenesis" RELATED [GOC:mah] is_a: GO:0000226 ! microtubule cytoskeleton organization is_a: GO:0097435 ! supramolecular fiber organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0005881 ! cytoplasmic microtubule relationship: results_in_organization_of GO:0005881 ! cytoplasmic microtubule [Term] id: GO:0031128 name: developmental induction namespace: biological_process def: "A developmental process involving two tissues in which one tissue (the inducer) produces a signal that directs cell fate commitment of cells in the second tissue (the responder)." [GOC:cjm, GOC:dph, GOC:mah, PMID:24503535] is_a: GO:0032502 ! developmental process intersection_of: GO:0032502 ! developmental process intersection_of: has_part GO:0045168 ! cell-cell signaling involved in cell fate commitment relationship: has_part GO:0045168 ! cell-cell signaling involved in cell fate commitment property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0031175 name: neuron projection development namespace: biological_process def: "The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." [GOC:mah] synonym: "neurite biosynthesis" NARROW [] synonym: "neurite development" NARROW [GOC:dph] synonym: "neurite formation" NARROW [] synonym: "neurite growth" NARROW [] synonym: "neurite outgrowth" NARROW [] is_a: GO:0120036 ! plasma membrane bounded cell projection organization intersection_of: GO:0120036 ! plasma membrane bounded cell projection organization intersection_of: part_of GO:0048666 ! neuron development relationship: part_of GO:0048666 ! neuron development [Term] id: GO:0031252 name: cell leading edge namespace: cellular_component def: "The area of a motile cell closest to the direction of movement." [GOC:pg] subset: goslim_pir synonym: "front of cell" EXACT [] synonym: "leading edge of cell" EXACT [] is_a: GO:0110165 ! cellular anatomical entity relationship: part_of CL:0000000 ! cell [Term] id: GO:0031253 name: cell projection membrane namespace: cellular_component def: "The portion of the plasma membrane surrounding a plasma membrane bounded cell surface projection." [GOC:krc, GOC:mah] synonym: "membrane extension" RELATED [] synonym: "membrane projection" RELATED [] is_a: GO:0098590 ! plasma membrane region intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0120025 ! plasma membrane bounded cell projection relationship: bounding_layer_of GO:0120025 ! plasma membrane bounded cell projection relationship: part_of GO:0120025 ! plasma membrane bounded cell projection [Term] id: GO:0031256 name: leading edge membrane namespace: cellular_component def: "The portion of the plasma membrane surrounding the leading edge of a motile cell." [GOC:mah] is_a: GO:0110165 ! cellular anatomical entity relationship: part_of GO:0005886 ! plasma membrane relationship: part_of GO:0031252 ! cell leading edge [Term] id: GO:0031323 name: regulation of cellular metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances." [GOC:mah] subset: gocheck_do_not_annotate synonym: "regulation of cellular metabolism" EXACT [] is_a: GO:0019222 ! regulation of metabolic process is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0044237 ! cellular metabolic process relationship: regulates GO:0044237 ! cellular metabolic process [Term] id: GO:0031324 name: negative regulation of cellular metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances." [GOC:mah] subset: gocheck_do_not_annotate synonym: "down regulation of cellular metabolic process" EXACT [] synonym: "down-regulation of cellular metabolic process" EXACT [] synonym: "downregulation of cellular metabolic process" EXACT [] synonym: "inhibition of cellular metabolic process" NARROW [] synonym: "negative regulation of cellular metabolism" EXACT [] is_a: GO:0009892 ! negative regulation of metabolic process is_a: GO:0031323 ! regulation of cellular metabolic process is_a: GO:0048523 ! negative regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0044237 ! cellular metabolic process relationship: negatively_regulates GO:0044237 ! cellular metabolic process [Term] id: GO:0031325 name: positive regulation of cellular metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances." [GOC:mah] subset: gocheck_do_not_annotate synonym: "activation of cellular metabolic process" NARROW [] synonym: "positive regulation of cellular metabolism" EXACT [] synonym: "stimulation of cellular metabolic process" NARROW [] synonym: "up regulation of cellular metabolic process" EXACT [] synonym: "up-regulation of cellular metabolic process" EXACT [] synonym: "upregulation of cellular metabolic process" EXACT [] is_a: GO:0009893 ! positive regulation of metabolic process is_a: GO:0031323 ! regulation of cellular metabolic process is_a: GO:0048522 ! positive regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0044237 ! cellular metabolic process relationship: positively_regulates GO:0044237 ! cellular metabolic process [Term] id: GO:0031326 name: regulation of cellular biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." [GOC:mah] synonym: "regulation of cellular anabolism" EXACT [] synonym: "regulation of cellular biosynthesis" EXACT [] synonym: "regulation of cellular formation" EXACT [] synonym: "regulation of cellular synthesis" EXACT [] is_a: GO:0009889 ! regulation of biosynthetic process is_a: GO:0031323 ! regulation of cellular metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0044249 ! cellular biosynthetic process relationship: regulates GO:0044249 ! cellular biosynthetic process [Term] id: GO:0031327 name: negative regulation of cellular biosynthetic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." [GOC:mah] synonym: "down regulation of cellular biosynthetic process" EXACT [] synonym: "down-regulation of cellular biosynthetic process" EXACT [] synonym: "downregulation of cellular biosynthetic process" EXACT [] synonym: "inhibition of cellular biosynthetic process" NARROW [] synonym: "negative regulation of cellular anabolism" EXACT [] synonym: "negative regulation of cellular biosynthesis" EXACT [] synonym: "negative regulation of cellular formation" EXACT [] synonym: "negative regulation of cellular synthesis" EXACT [] is_a: GO:0009890 ! negative regulation of biosynthetic process is_a: GO:0031324 ! negative regulation of cellular metabolic process is_a: GO:0031326 ! regulation of cellular biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0044249 ! cellular biosynthetic process relationship: negatively_regulates GO:0044249 ! cellular biosynthetic process [Term] id: GO:0031328 name: positive regulation of cellular biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." [GOC:mah] synonym: "activation of cellular biosynthetic process" NARROW [] synonym: "positive regulation of cellular anabolism" EXACT [] synonym: "positive regulation of cellular biosynthesis" EXACT [] synonym: "positive regulation of cellular formation" EXACT [] synonym: "positive regulation of cellular synthesis" EXACT [] synonym: "stimulation of cellular biosynthetic process" NARROW [] synonym: "up regulation of cellular biosynthetic process" EXACT [] synonym: "up-regulation of cellular biosynthetic process" EXACT [] synonym: "upregulation of cellular biosynthetic process" EXACT [] is_a: GO:0009891 ! positive regulation of biosynthetic process is_a: GO:0031325 ! positive regulation of cellular metabolic process is_a: GO:0031326 ! regulation of cellular biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0044249 ! cellular biosynthetic process relationship: positively_regulates GO:0044249 ! cellular biosynthetic process [Term] id: GO:0031329 name: regulation of cellular catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells." [GOC:mah] synonym: "regulation of cellular breakdown" EXACT [] synonym: "regulation of cellular catabolism" EXACT [] synonym: "regulation of cellular degradation" EXACT [] is_a: GO:0009894 ! regulation of catabolic process is_a: GO:0031323 ! regulation of cellular metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0044248 ! cellular catabolic process relationship: regulates GO:0044248 ! cellular catabolic process [Term] id: GO:0031330 name: negative regulation of cellular catabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells." [GOC:mah] synonym: "down regulation of cellular catabolic process" EXACT [] synonym: "down-regulation of cellular catabolic process" EXACT [] synonym: "downregulation of cellular catabolic process" EXACT [] synonym: "inhibition of cellular catabolic process" NARROW [] synonym: "negative regulation of cellular breakdown" EXACT [] synonym: "negative regulation of cellular catabolism" EXACT [] synonym: "negative regulation of cellular degradation" EXACT [] is_a: GO:0009895 ! negative regulation of catabolic process is_a: GO:0031324 ! negative regulation of cellular metabolic process is_a: GO:0031329 ! regulation of cellular catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0044248 ! cellular catabolic process relationship: negatively_regulates GO:0044248 ! cellular catabolic process [Term] id: GO:0031331 name: positive regulation of cellular catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells." [GOC:mah] synonym: "activation of cellular catabolic process" NARROW [] synonym: "positive regulation of cellular breakdown" EXACT [] synonym: "positive regulation of cellular catabolism" EXACT [] synonym: "positive regulation of cellular degradation" EXACT [] synonym: "stimulation of cellular catabolic process" NARROW [] synonym: "up regulation of cellular catabolic process" EXACT [] synonym: "up-regulation of cellular catabolic process" EXACT [] synonym: "upregulation of cellular catabolic process" EXACT [] is_a: GO:0009896 ! positive regulation of catabolic process is_a: GO:0031325 ! positive regulation of cellular metabolic process is_a: GO:0031329 ! regulation of cellular catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0044248 ! cellular catabolic process relationship: positively_regulates GO:0044248 ! cellular catabolic process [Term] id: GO:0031333 name: negative regulation of protein-containing complex assembly namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly." [GOC:mah] synonym: "down regulation of protein complex assembly" EXACT [] synonym: "down-regulation of protein complex assembly" EXACT [] synonym: "downregulation of protein complex assembly" EXACT [] synonym: "inhibition of protein complex assembly" NARROW [] synonym: "negative regulation of protein complex assembly" RELATED [] is_a: GO:0043254 ! regulation of protein-containing complex assembly is_a: GO:0051129 ! negative regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0065003 ! protein-containing complex assembly relationship: negatively_regulates GO:0065003 ! protein-containing complex assembly [Term] id: GO:0031334 name: positive regulation of protein-containing complex assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein complex assembly." [GOC:mah] synonym: "activation of protein complex assembly" NARROW [] synonym: "positive regulation of protein complex assembly" RELATED [] synonym: "stimulation of protein complex assembly" NARROW [] synonym: "up regulation of protein complex assembly" EXACT [] synonym: "up-regulation of protein complex assembly" EXACT [] synonym: "upregulation of protein complex assembly" EXACT [] is_a: GO:0043254 ! regulation of protein-containing complex assembly is_a: GO:0044089 ! positive regulation of cellular component biogenesis is_a: GO:0051130 ! positive regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0065003 ! protein-containing complex assembly relationship: positively_regulates GO:0065003 ! protein-containing complex assembly [Term] id: GO:0031338 name: regulation of vesicle fusion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of vesicle fusion." [GOC:mah] is_a: GO:0033043 ! regulation of organelle organization is_a: GO:0060627 ! regulation of vesicle-mediated transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006906 ! vesicle fusion relationship: regulates GO:0006906 ! vesicle fusion [Term] id: GO:0031339 name: negative regulation of vesicle fusion namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of vesicle fusion." [GOC:mah] synonym: "down regulation of vesicle fusion" EXACT [] synonym: "down-regulation of vesicle fusion" EXACT [] synonym: "downregulation of vesicle fusion" EXACT [] synonym: "inhibition of vesicle fusion" NARROW [] is_a: GO:0010639 ! negative regulation of organelle organization is_a: GO:0031338 ! regulation of vesicle fusion is_a: GO:0051051 ! negative regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006906 ! vesicle fusion relationship: negatively_regulates GO:0006906 ! vesicle fusion [Term] id: GO:0031340 name: positive regulation of vesicle fusion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of vesicle fusion." [GOC:mah] synonym: "activation of vesicle fusion" NARROW [] synonym: "stimulation of vesicle fusion" NARROW [] synonym: "up regulation of vesicle fusion" EXACT [] synonym: "up-regulation of vesicle fusion" EXACT [] synonym: "upregulation of vesicle fusion" EXACT [] is_a: GO:0010638 ! positive regulation of organelle organization is_a: GO:0031338 ! regulation of vesicle fusion is_a: GO:0051050 ! positive regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006906 ! vesicle fusion relationship: positively_regulates GO:0006906 ! vesicle fusion [Term] id: GO:0031344 name: regulation of cell projection organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections." [GOC:mah] synonym: "regulation of cell projection organisation" EXACT [] synonym: "regulation of cell projection organization and biogenesis" RELATED [GOC:mah] is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030030 ! cell projection organization relationship: regulates GO:0030030 ! cell projection organization [Term] id: GO:0031345 name: negative regulation of cell projection organization namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections." [GOC:mah] synonym: "down regulation of cell projection organization" EXACT [GOC:mah] synonym: "down-regulation of cell projection organization" EXACT [] synonym: "downregulation of cell projection organization" EXACT [] synonym: "inhibition of cell projection organization" NARROW [] synonym: "negative regulation of cell projection organisation" EXACT [] synonym: "negative regulation of cell projection organization and biogenesis" RELATED [GOC:mah] is_a: GO:0031344 ! regulation of cell projection organization is_a: GO:0051129 ! negative regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030030 ! cell projection organization relationship: negatively_regulates GO:0030030 ! cell projection organization [Term] id: GO:0031346 name: positive regulation of cell projection organization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the process involved in the formation, arrangement of constituent parts, or disassembly of cell projections." [GOC:mah] synonym: "activation of cell projection organization" NARROW [] synonym: "positive regulation of cell projection organisation" EXACT [] synonym: "positive regulation of cell projection organization and biogenesis" RELATED [GOC:mah] synonym: "stimulation of cell projection organization" NARROW [] synonym: "up regulation of cell projection organization" EXACT [] synonym: "up-regulation of cell projection organization" EXACT [] synonym: "upregulation of cell projection organization" EXACT [] is_a: GO:0031344 ! regulation of cell projection organization is_a: GO:0051130 ! positive regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030030 ! cell projection organization relationship: positively_regulates GO:0030030 ! cell projection organization [Term] id: GO:0031347 name: regulation of defense response namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a defense response." [GOC:mah] is_a: GO:0080134 ! regulation of response to stress intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006952 ! defense response relationship: regulates GO:0006952 ! defense response [Term] id: GO:0031348 name: negative regulation of defense response namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response." [GOC:mah] synonym: "down regulation of defense response" EXACT [] synonym: "down-regulation of defense response" EXACT [] synonym: "downregulation of defense response" EXACT [] synonym: "inhibition of defense response" NARROW [] is_a: GO:0031347 ! regulation of defense response is_a: GO:0048585 ! negative regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006952 ! defense response relationship: negatively_regulates GO:0006952 ! defense response [Term] id: GO:0031349 name: positive regulation of defense response namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of a defense response." [GOC:mah] synonym: "activation of defense response" NARROW [] synonym: "stimulation of defense response" NARROW [] synonym: "up regulation of defense response" EXACT [] synonym: "up-regulation of defense response" EXACT [] synonym: "upregulation of defense response" EXACT [] is_a: GO:0031347 ! regulation of defense response is_a: GO:0048584 ! positive regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006952 ! defense response relationship: positively_regulates GO:0006952 ! defense response [Term] id: GO:0031410 name: cytoplasmic vesicle namespace: cellular_component alt_id: GO:0016023 def: "A vesicle found in the cytoplasm of a cell." [GOC:ai, GOC:mah, GOC:vesicles] subset: goslim_agr subset: goslim_candida subset: goslim_chembl subset: goslim_generic subset: goslim_mouse subset: goslim_yeast synonym: "cytoplasmic membrane bounded vesicle" RELATED [] synonym: "cytoplasmic membrane-enclosed vesicle" RELATED [] synonym: "cytoplasmic, membrane-bounded vesicle" RELATED [] xref: NIF_Subcellular:sao180601769 is_a: GO:0097708 ! intracellular vesicle intersection_of: GO:0031982 ! vesicle intersection_of: part_of GO:0005737 ! cytoplasm relationship: part_of GO:0005737 ! cytoplasm [Term] id: GO:0031503 name: protein-containing complex localization namespace: biological_process alt_id: GO:0034629 def: "A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location." [GOC:mah] synonym: "cellular protein complex localisation" RELATED [GOC:mah] synonym: "cellular protein complex localization" RELATED [] synonym: "cellular protein-containing complex localization" RELATED [] synonym: "establishment and maintenance of cellular protein complex localization" RELATED [] synonym: "establishment and maintenance of protein complex localization" EXACT [] synonym: "protein complex localisation" EXACT [GOC:mah] synonym: "protein complex localization" RELATED [] is_a: GO:0051179 ! localization intersection_of: GO:0051179 ! localization intersection_of: has_primary_input GO:0032991 ! protein-containing complex relationship: has_primary_input GO:0032991 ! protein-containing complex property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22021" xsd:anyURI [Term] id: GO:0031514 name: motile cilium namespace: cellular_component alt_id: GO:0009434 alt_id: GO:0031512 def: "A cilium which may have a variable arrangement of axonemal microtubules and also contains molecular motors. It may beat with a whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface, such as on epithelial cells that line the lumenal ducts of various tissues; or they may display a distinct twirling motion that directs fluid flow asymmetrically across the cellular surface to affect asymmetric body plan organization. Motile cilia can be found in single as well as multiple copies per cell." [GOC:cilia, GOC:dgh, GOC:kmv, PMID:17009929, PMID:20144998, PMID:22118931] synonym: "microtubule-based flagellum" RELATED [] synonym: "motile cilia" EXACT [] synonym: "motile primary cilia" RELATED [] synonym: "motile primary cilium" RELATED [] synonym: "motile secondary cilium" RELATED [] synonym: "nodal cilium" RELATED [] is_a: GO:0005929 ! cilium intersection_of: GO:0005929 ! cilium intersection_of: capable_of GO:0003341 ! cilium movement relationship: capable_of GO:0003341 ! cilium movement [Term] id: GO:0031594 name: neuromuscular junction namespace: cellular_component def: "The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential." [GOC:nln] comment: In vertebrates, the term 'neuromuscular junction' is limited to synapses targeting skeletal muscle fibers - all of which are cholinergic and excitatory. Both inhibitory and excitatory neuromuscular junctions exist in invertebrates, utilizing a range of neurotransmitters including glutamate, GABA and 5-HT. synonym: "motor endplate" RELATED [NIF_Subcellular:nlx_subcell_20090512] synonym: "NMJ" RELATED [GOC:ha] xref: NIF_Subcellular:sao1124888485 xref: Wikipedia:Neuromuscular_junction is_a: GO:0045202 ! synapse intersection_of: GO:0045202 ! synapse intersection_of: overlaps CL:0000100 ! motor neuron intersection_of: overlaps CL:0000187 ! muscle cell relationship: overlaps CL:0000100 ! motor neuron relationship: overlaps CL:0000187 ! muscle cell [Term] id: GO:0031644 name: regulation of nervous system process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of the nervous system." [GOC:dph, GOC:mah, GOC:tb] synonym: "regulation of neurological process" EXACT [GOC:dph, GOC:tb] synonym: "regulation of neurological system process" EXACT [] synonym: "regulation of neurophysiological process" EXACT [] is_a: GO:0044057 ! regulation of system process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0050877 ! nervous system process relationship: regulates GO:0050877 ! nervous system process [Term] id: GO:0031645 name: negative regulation of nervous system process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a neurophysiological process." [GOC:dph, GOC:mah, GOC:tb] synonym: "down regulation of neurological process" EXACT [] synonym: "down-regulation of neurological process" EXACT [] synonym: "downregulation of neurological process" EXACT [] synonym: "inhibition of neurological process" NARROW [] synonym: "negative regulation of neurological process" EXACT [GOC:dph, GOC:tb] synonym: "negative regulation of neurological system process" EXACT [] synonym: "negative regulation of neurophysiological process" EXACT [] is_a: GO:0031644 ! regulation of nervous system process is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0050877 ! nervous system process relationship: negatively_regulates GO:0050877 ! nervous system process [Term] id: GO:0031646 name: positive regulation of nervous system process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of a neurophysiological process." [GOC:dph, GOC:mah, GOC:tb] synonym: "activation of neurological process" NARROW [] synonym: "positive regulation of neurological process" EXACT [GOC:dph, GOC:tb] synonym: "positive regulation of neurological system process" EXACT [] synonym: "positive regulation of neurophysiological process" EXACT [] synonym: "stimulation of neurological process" NARROW [] synonym: "up regulation of neurological process" EXACT [] synonym: "up-regulation of neurological process" EXACT [] synonym: "upregulation of neurological process" EXACT [] is_a: GO:0031644 ! regulation of nervous system process is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0050877 ! nervous system process relationship: positively_regulates GO:0050877 ! nervous system process [Term] id: GO:0031965 name: nuclear membrane namespace: cellular_component def: "Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space." [GOC:mah, GOC:pz] xref: NIF_Subcellular:sao1687101204 is_a: GO:0031090 ! organelle membrane intersection_of: GO:0016020 ! membrane intersection_of: part_of GO:0005634 ! nucleus relationship: part_of GO:0005635 ! nuclear envelope [Term] id: GO:0031967 name: organelle envelope namespace: cellular_component def: "A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes." [GOC:mah, GOC:pz] subset: goslim_mouse is_a: GO:0031975 ! envelope relationship: part_of GO:0043227 ! membrane-bounded organelle relationship: part_of GO:0043229 ! intracellular organelle [Term] id: GO:0031968 name: organelle outer membrane namespace: cellular_component def: "The outer, i.e. cytoplasm-facing in a cellular organelle, lipid bilayer of an organelle envelope." [GOC:mah] is_a: GO:0019867 ! outer membrane is_a: GO:0098588 ! bounding membrane of organelle intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0043226 ! organelle intersection_of: part_of GO:0031967 ! organelle envelope relationship: part_of GO:0031967 ! organelle envelope [Term] id: GO:0031974 name: membrane-enclosed lumen namespace: cellular_component def: "The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen." [GOC:add, GOC:mah] is_a: GO:0110165 ! cellular anatomical entity disjoint_from: GO:0045202 ! synapse [Term] id: GO:0031975 name: envelope namespace: cellular_component def: "A multilayered structure surrounding all or part of a cell; encompasses one or more lipid bilayers, and may include a cell wall layer; also includes the space between layers." [GOC:mah, GOC:pz] is_a: GO:0110165 ! cellular anatomical entity relationship: part_of CL:0000000 ! cell [Term] id: GO:0031981 name: nuclear lumen namespace: cellular_component def: "The volume enclosed by the nuclear inner membrane." [GOC:mah, GOC:pz] is_a: GO:0070013 ! intracellular organelle lumen relationship: part_of GO:0005634 ! nucleus [Term] id: GO:0031982 name: vesicle namespace: cellular_component alt_id: GO:0031988 def: "Any small, fluid-filled, spherical organelle enclosed by membrane." [GOC:mah, GOC:pz, GOC:vesicles] subset: goslim_pir synonym: "membrane-bounded vesicle" RELATED [] synonym: "membrane-enclosed vesicle" RELATED [] xref: NIF_Subcellular:sao221389602 xref: Wikipedia:Vesicle_(biology) is_a: GO:0043227 ! membrane-bounded organelle [Term] id: GO:0031987 name: locomotion involved in locomotory behavior namespace: biological_process def: "Self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement." [GOC:mah] synonym: "locomotion during locomotory behaviour" EXACT [] is_a: GO:0040011 ! locomotion intersection_of: GO:0040011 ! locomotion intersection_of: part_of GO:0007626 ! locomotory behavior relationship: part_of GO:0007626 ! locomotory behavior [Term] id: GO:0032024 name: positive regulation of insulin secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of insulin." [GOC:mah] synonym: "activation of insulin secretion" NARROW [] synonym: "stimulation of insulin secretion" NARROW [] synonym: "up regulation of insulin secretion" EXACT [] synonym: "up-regulation of insulin secretion" EXACT [] synonym: "upregulation of insulin secretion" EXACT [] is_a: GO:0050714 ! positive regulation of protein secretion is_a: GO:0050796 ! regulation of insulin secretion is_a: GO:0090277 ! positive regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030073 ! insulin secretion relationship: positively_regulates GO:0030073 ! insulin secretion [Term] id: GO:0032057 name: negative regulation of translational initiation in response to stress namespace: biological_process def: "Any process that stops, prevents or reduces the rate of translation initiation as a result of a stimulus indicating the organism is under stress." [GOC:mah] synonym: "down regulation of translation initiation in response to stress" EXACT [] synonym: "down-regulation of translation initiation in response to stress" EXACT [] synonym: "downregulation of translation initiation in response to stress" EXACT [] synonym: "inhibition of translation initiation in response to stress" NARROW [] is_a: GO:0045947 ! negative regulation of translational initiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006413 ! translational initiation intersection_of: part_of GO:0006950 ! response to stress relationship: part_of GO:0006950 ! response to stress [Term] id: GO:0032058 name: positive regulation of translational initiation in response to stress namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of translation initiation as a result of a stimulus indicating the organism is under stress." [GOC:mah] synonym: "activation of translation initiation in response to stress" NARROW [] synonym: "stimulation of translation initiation in response to stress" NARROW [] synonym: "up regulation of translation initiation in response to stress" EXACT [] synonym: "up-regulation of translation initiation in response to stress" EXACT [] synonym: "upregulation of translation initiation in response to stress" EXACT [] is_a: GO:0045948 ! positive regulation of translational initiation intersection_of: GO:0065007 ! biological regulation intersection_of: part_of GO:0006950 ! response to stress intersection_of: positively_regulates GO:0006413 ! translational initiation relationship: part_of GO:0006950 ! response to stress [Term] id: GO:0032059 name: bleb namespace: cellular_component def: "A cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Blebs are formed during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses." [GOC:mtg_apoptosis, PMID:12083798, PMID:16624291, Wikipedia:Bleb_(cell_biology)] subset: goslim_pir synonym: "plasma membrane bleb" EXACT [GOC:pr] xref: Wikipedia:Bleb_(cell_biology) is_a: GO:0120025 ! plasma membrane bounded cell projection [Term] id: GO:0032060 name: bleb assembly namespace: biological_process def: "The assembly of a bleb, a cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Plasma membrane blebbing occurs during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses." [GOC:mah, GOC:mtg_apoptosis, PMID:12083798, PMID:16624291, Wikipedia:Bleb_(cell_biology)] synonym: "blebbing" BROAD [GOC:pr] synonym: "cell blebbing" EXACT [] synonym: "membrane blebbing" BROAD [GOC:pr] synonym: "plasma membrane bleb assembly" EXACT [GOC:pr] synonym: "plasma membrane blebbing" EXACT [GOC:pr] is_a: GO:0120031 ! plasma membrane bounded cell projection assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0032059 ! bleb relationship: results_in_assembly_of GO:0032059 ! bleb [Term] id: GO:0032069 name: regulation of nuclease activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids." [GOC:mah] subset: gocheck_do_not_annotate synonym: "nuclease regulator activity" RELATED [] is_a: GO:0051336 ! regulation of hydrolase activity is_a: GO:0060255 ! regulation of macromolecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0004518 ! nuclease activity relationship: regulates GO:0004518 ! nuclease activity [Term] id: GO:0032070 name: regulation of deoxyribonuclease activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid." [GOC:mah] subset: gocheck_do_not_annotate synonym: "deoxyribonuclease regulator" RELATED [] synonym: "DNase regulator" RELATED [] is_a: GO:0032069 ! regulation of nuclease activity is_a: GO:0051052 ! regulation of DNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0004536 ! DNA nuclease activity relationship: regulates GO:0004536 ! DNA nuclease activity [Term] id: GO:0032074 name: negative regulation of nuclease activity namespace: biological_process def: "Any process that stops or reduces the rate of nuclease activity, the hydrolysis of ester linkages within nucleic acids." [GOC:mah] subset: gocheck_do_not_annotate synonym: "down regulation of nuclease activity" EXACT [] synonym: "down-regulation of nuclease activity" EXACT [] synonym: "downregulation of nuclease activity" EXACT [] synonym: "inhibition of nuclease activity" NARROW [] synonym: "nuclease inhibitor" RELATED [] is_a: GO:0032069 ! regulation of nuclease activity is_a: GO:0045934 ! negative regulation of nucleobase-containing compound metabolic process is_a: GO:0051346 ! negative regulation of hydrolase activity intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0004518 ! nuclease activity relationship: negatively_regulates GO:0004518 ! nuclease activity [Term] id: GO:0032075 name: positive regulation of nuclease activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids." [GOC:mah] subset: gocheck_do_not_annotate synonym: "activation of nuclease activity" NARROW [] synonym: "nuclease activator" RELATED [] synonym: "stimulation of nuclease activity" NARROW [] synonym: "up regulation of nuclease activity" EXACT [] synonym: "up-regulation of nuclease activity" EXACT [] synonym: "upregulation of nuclease activity" EXACT [] is_a: GO:0032069 ! regulation of nuclease activity is_a: GO:0045935 ! positive regulation of nucleobase-containing compound metabolic process is_a: GO:0051345 ! positive regulation of hydrolase activity intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0004518 ! nuclease activity relationship: positively_regulates GO:0004518 ! nuclease activity [Term] id: GO:0032076 name: negative regulation of deoxyribonuclease activity namespace: biological_process def: "Any process that stops or reduces the rate of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid." [GOC:mah] subset: gocheck_do_not_annotate synonym: "deoxyribonuclease inhibitor" RELATED [] synonym: "DNase inhibitor" RELATED [] synonym: "down regulation of deoxyribonuclease activity" EXACT [] synonym: "down-regulation of deoxyribonuclease activity" EXACT [] synonym: "downregulation of deoxyribonuclease activity" EXACT [] synonym: "inhibition of deoxyribonuclease activity" NARROW [] is_a: GO:0032070 ! regulation of deoxyribonuclease activity is_a: GO:0032074 ! negative regulation of nuclease activity is_a: GO:0051053 ! negative regulation of DNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0004536 ! DNA nuclease activity relationship: negatively_regulates GO:0004536 ! DNA nuclease activity [Term] id: GO:0032077 name: positive regulation of deoxyribonuclease activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid." [GOC:mah] subset: gocheck_do_not_annotate synonym: "activation of deoxyribonuclease activity" NARROW [] synonym: "deoxyribonuclease activator" RELATED [] synonym: "DNase activator" RELATED [] synonym: "stimulation of deoxyribonuclease activity" NARROW [] synonym: "up regulation of deoxyribonuclease activity" EXACT [] synonym: "up-regulation of deoxyribonuclease activity" EXACT [] synonym: "upregulation of deoxyribonuclease activity" EXACT [] is_a: GO:0032070 ! regulation of deoxyribonuclease activity is_a: GO:0032075 ! positive regulation of nuclease activity is_a: GO:0051054 ! positive regulation of DNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0004536 ! DNA nuclease activity relationship: positively_regulates GO:0004536 ! DNA nuclease activity [Term] id: GO:0032101 name: regulation of response to external stimulus namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a response to an external stimulus." [GOC:mah] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_manually_annotate is_a: GO:0048583 ! regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0009605 ! response to external stimulus relationship: regulates GO:0009605 ! response to external stimulus [Term] id: GO:0032102 name: negative regulation of response to external stimulus namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an external stimulus." [GOC:mah] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_manually_annotate synonym: "down regulation of response to external stimulus" EXACT [] synonym: "down-regulation of response to external stimulus" EXACT [] synonym: "downregulation of response to external stimulus" EXACT [] synonym: "inhibition of response to external stimulus" NARROW [] is_a: GO:0032101 ! regulation of response to external stimulus is_a: GO:0048585 ! negative regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0009605 ! response to external stimulus relationship: negatively_regulates GO:0009605 ! response to external stimulus [Term] id: GO:0032103 name: positive regulation of response to external stimulus namespace: biological_process def: "Any process that activates, maintains or increases the rate of a response to an external stimulus." [GOC:mah] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_manually_annotate synonym: "activation of response to external stimulus" NARROW [] synonym: "stimulation of response to external stimulus" NARROW [] synonym: "up regulation of response to external stimulus" EXACT [] synonym: "up-regulation of response to external stimulus" EXACT [] synonym: "upregulation of response to external stimulus" EXACT [] is_a: GO:0032101 ! regulation of response to external stimulus is_a: GO:0048584 ! positive regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0009605 ! response to external stimulus relationship: positively_regulates GO:0009605 ! response to external stimulus [Term] id: GO:0032127 name: dense core granule membrane namespace: cellular_component def: "The lipid bilayer surrounding a dense core granule." [GOC:mah] synonym: "dense core vesicle membrane" EXACT [GOC:kmv] is_a: GO:0030667 ! secretory granule membrane intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0031045 ! dense core granule relationship: bounding_layer_of GO:0031045 ! dense core granule relationship: part_of GO:0031045 ! dense core granule [Term] id: GO:0032222 name: regulation of synaptic transmission, cholinergic namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine." [GOC:mah] is_a: GO:0050804 ! modulation of chemical synaptic transmission intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007271 ! synaptic transmission, cholinergic relationship: regulates GO:0007271 ! synaptic transmission, cholinergic [Term] id: GO:0032223 name: negative regulation of synaptic transmission, cholinergic namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine." [GOC:mah] synonym: "down regulation of synaptic transmission, cholinergic" EXACT [] synonym: "down-regulation of synaptic transmission, cholinergic" EXACT [] synonym: "downregulation of synaptic transmission, cholinergic" EXACT [] synonym: "inhibition of synaptic transmission, cholinergic" NARROW [] is_a: GO:0032222 ! regulation of synaptic transmission, cholinergic is_a: GO:0050805 ! negative regulation of synaptic transmission intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007271 ! synaptic transmission, cholinergic relationship: negatively_regulates GO:0007271 ! synaptic transmission, cholinergic [Term] id: GO:0032224 name: positive regulation of synaptic transmission, cholinergic namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine." [GOC:mah] synonym: "activation of synaptic transmission, cholinergic" NARROW [] synonym: "stimulation of synaptic transmission, cholinergic" NARROW [] synonym: "up regulation of synaptic transmission, cholinergic" EXACT [] synonym: "up-regulation of synaptic transmission, cholinergic" EXACT [] synonym: "upregulation of synaptic transmission, cholinergic" EXACT [] is_a: GO:0032222 ! regulation of synaptic transmission, cholinergic is_a: GO:0050806 ! positive regulation of synaptic transmission intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007271 ! synaptic transmission, cholinergic relationship: positively_regulates GO:0007271 ! synaptic transmission, cholinergic [Term] id: GO:0032231 name: regulation of actin filament bundle assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the assembly of actin filament bundles." [GOC:mah] synonym: "regulation of actin cable assembly" EXACT [GOC:dph, GOC:tb] synonym: "regulation of actin filament bundle formation" RELATED [GOC:dph] is_a: GO:0044087 ! regulation of cellular component biogenesis is_a: GO:0110053 ! regulation of actin filament organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0051017 ! actin filament bundle assembly relationship: regulates GO:0051017 ! actin filament bundle assembly [Term] id: GO:0032232 name: negative regulation of actin filament bundle assembly namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of actin filament bundles." [GOC:mah] synonym: "down regulation of actin filament bundle formation" EXACT [] synonym: "down-regulation of actin filament bundle formation" EXACT [] synonym: "downregulation of actin filament bundle formation" EXACT [] synonym: "inhibition of actin filament bundle formation" NARROW [] is_a: GO:0032231 ! regulation of actin filament bundle assembly is_a: GO:0051494 ! negative regulation of cytoskeleton organization is_a: GO:1902904 ! negative regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0051017 ! actin filament bundle assembly relationship: negatively_regulates GO:0051017 ! actin filament bundle assembly [Term] id: GO:0032233 name: positive regulation of actin filament bundle assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the assembly of actin filament bundles." [GOC:mah] synonym: "activation of actin filament bundle formation" NARROW [] synonym: "stimulation of actin filament bundle formation" NARROW [] synonym: "up regulation of actin filament bundle formation" EXACT [] synonym: "up-regulation of actin filament bundle formation" EXACT [] synonym: "upregulation of actin filament bundle formation" EXACT [] is_a: GO:0032231 ! regulation of actin filament bundle assembly is_a: GO:0044089 ! positive regulation of cellular component biogenesis is_a: GO:0051495 ! positive regulation of cytoskeleton organization is_a: GO:1902905 ! positive regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0051017 ! actin filament bundle assembly relationship: positively_regulates GO:0051017 ! actin filament bundle assembly [Term] id: GO:0032239 name: regulation of nucleobase-containing compound transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] synonym: "regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" RELATED [GOC:dph, GOC:tb] is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0015931 ! nucleobase-containing compound transport relationship: regulates GO:0015931 ! nucleobase-containing compound transport [Term] id: GO:0032240 name: negative regulation of nucleobase-containing compound transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] synonym: "down regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" EXACT [] synonym: "down-regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" EXACT [] synonym: "downregulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" EXACT [] synonym: "inhibition of nucleobase, nucleoside, nucleotide and nucleic acid transport" NARROW [] synonym: "negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" RELATED [GOC:dph, GOC:tb] is_a: GO:0032239 ! regulation of nucleobase-containing compound transport is_a: GO:0051051 ! negative regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0015931 ! nucleobase-containing compound transport relationship: negatively_regulates GO:0015931 ! nucleobase-containing compound transport [Term] id: GO:0032241 name: positive regulation of nucleobase-containing compound transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] synonym: "activation of nucleobase, nucleoside, nucleotide and nucleic acid transport" NARROW [] synonym: "positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" RELATED [GOC:dph, GOC:tb] synonym: "stimulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" NARROW [] synonym: "up regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" EXACT [] synonym: "up-regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" EXACT [] synonym: "upregulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" EXACT [] is_a: GO:0032239 ! regulation of nucleobase-containing compound transport is_a: GO:0051050 ! positive regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0015931 ! nucleobase-containing compound transport relationship: positively_regulates GO:0015931 ! nucleobase-containing compound transport [Term] id: GO:0032252 name: secretory granule localization namespace: biological_process def: "Any process in which a secretory granule is transported to, and/or maintained in, a specific location within the cell." [GOC:mah] synonym: "secretory granule clustering" RELATED [] synonym: "secretory granule localisation" EXACT [GOC:mah] is_a: GO:0051648 ! vesicle localization intersection_of: GO:0051179 ! localization intersection_of: has_primary_input GO:0030141 ! secretory granule relationship: has_primary_input GO:0030141 ! secretory granule [Term] id: GO:0032253 name: dense core granule localization namespace: biological_process def: "Any process in which a dense core granule is transported to, and/or maintained in, a specific location within the cell." [GOC:mah] synonym: "dense core granule clustering" RELATED [] synonym: "dense core granule localisation" EXACT [GOC:mah] synonym: "dense core vesicle localization" EXACT [GOC:kmv] is_a: GO:0032252 ! secretory granule localization intersection_of: GO:0051179 ! localization intersection_of: has_primary_input GO:0031045 ! dense core granule relationship: has_primary_input GO:0031045 ! dense core granule [Term] id: GO:0032271 name: regulation of protein polymerization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the process of creating protein polymers." [GOC:mah] synonym: "regulation of protein polymerisation" EXACT [] is_a: GO:0043254 ! regulation of protein-containing complex assembly intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0051258 ! protein polymerization relationship: regulates GO:0051258 ! protein polymerization [Term] id: GO:0032272 name: negative regulation of protein polymerization namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the process of creating protein polymers." [GOC:mah] synonym: "down regulation of protein polymerization" EXACT [] synonym: "down-regulation of protein polymerization" EXACT [] synonym: "downregulation of protein polymerization" EXACT [] synonym: "inhibition of protein polymerization" NARROW [] is_a: GO:0031333 ! negative regulation of protein-containing complex assembly is_a: GO:0032271 ! regulation of protein polymerization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0051258 ! protein polymerization relationship: negatively_regulates GO:0051258 ! protein polymerization [Term] id: GO:0032273 name: positive regulation of protein polymerization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the process of creating protein polymers." [GOC:mah] synonym: "activation of protein polymerization" NARROW [] synonym: "stimulation of protein polymerization" NARROW [] synonym: "up regulation of protein polymerization" EXACT [] synonym: "up-regulation of protein polymerization" EXACT [] synonym: "upregulation of protein polymerization" EXACT [] is_a: GO:0031334 ! positive regulation of protein-containing complex assembly is_a: GO:0032271 ! regulation of protein polymerization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0051258 ! protein polymerization relationship: positively_regulates GO:0051258 ! protein polymerization [Term] id: GO:0032330 name: regulation of chondrocyte differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of chondrocyte differentiation." [GOC:mah] is_a: GO:0045595 ! regulation of cell differentiation is_a: GO:0061035 ! regulation of cartilage development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002062 ! chondrocyte differentiation relationship: regulates GO:0002062 ! chondrocyte differentiation [Term] id: GO:0032331 name: negative regulation of chondrocyte differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of chondrocyte differentiation." [GOC:mah] synonym: "down regulation of chondrocyte differentiation" EXACT [] synonym: "down-regulation of chondrocyte differentiation" EXACT [] synonym: "downregulation of chondrocyte differentiation" EXACT [] synonym: "inhibition of chondrocyte differentiation" NARROW [] is_a: GO:0032330 ! regulation of chondrocyte differentiation is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0061037 ! negative regulation of cartilage development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002062 ! chondrocyte differentiation relationship: negatively_regulates GO:0002062 ! chondrocyte differentiation [Term] id: GO:0032332 name: positive regulation of chondrocyte differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of chondrocyte differentiation." [GOC:mah] synonym: "activation of chondrocyte differentiation" NARROW [] synonym: "stimulation of chondrocyte differentiation" NARROW [] synonym: "up regulation of chondrocyte differentiation" EXACT [] synonym: "up-regulation of chondrocyte differentiation" EXACT [] synonym: "upregulation of chondrocyte differentiation" EXACT [] is_a: GO:0032330 ! regulation of chondrocyte differentiation is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0061036 ! positive regulation of cartilage development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002062 ! chondrocyte differentiation relationship: positively_regulates GO:0002062 ! chondrocyte differentiation [Term] id: GO:0032365 name: intracellular lipid transport namespace: biological_process def: "The directed movement of lipids within cells." [GOC:mah] is_a: GO:0006869 ! lipid transport is_a: GO:0046907 ! intracellular transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:18059 ! lipid intersection_of: occurs_in GO:0005622 ! intracellular anatomical structure [Term] id: GO:0032368 name: regulation of lipid transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] is_a: GO:0051049 ! regulation of transport is_a: GO:1905952 ! regulation of lipid localization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006869 ! lipid transport relationship: regulates GO:0006869 ! lipid transport [Term] id: GO:0032369 name: negative regulation of lipid transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] synonym: "down regulation of lipid transport" EXACT [] synonym: "down-regulation of lipid transport" EXACT [] synonym: "downregulation of lipid transport" EXACT [] synonym: "inhibition of lipid transport" NARROW [] is_a: GO:0032368 ! regulation of lipid transport is_a: GO:0051051 ! negative regulation of transport is_a: GO:1905953 ! negative regulation of lipid localization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006869 ! lipid transport relationship: negatively_regulates GO:0006869 ! lipid transport [Term] id: GO:0032370 name: positive regulation of lipid transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] synonym: "activation of lipid transport" NARROW [] synonym: "stimulation of lipid transport" NARROW [] synonym: "up regulation of lipid transport" EXACT [] synonym: "up-regulation of lipid transport" EXACT [] synonym: "upregulation of lipid transport" EXACT [] is_a: GO:0032368 ! regulation of lipid transport is_a: GO:0051050 ! positive regulation of transport is_a: GO:1905954 ! positive regulation of lipid localization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006869 ! lipid transport relationship: positively_regulates GO:0006869 ! lipid transport [Term] id: GO:0032377 name: regulation of intracellular lipid transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of lipids within cells." [GOC:mah] is_a: GO:0032368 ! regulation of lipid transport is_a: GO:0032386 ! regulation of intracellular transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0032365 ! intracellular lipid transport relationship: regulates GO:0032365 ! intracellular lipid transport [Term] id: GO:0032378 name: negative regulation of intracellular lipid transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids within cells." [GOC:mah] synonym: "down regulation of intracellular lipid transport" EXACT [] synonym: "down-regulation of intracellular lipid transport" EXACT [] synonym: "downregulation of intracellular lipid transport" EXACT [] synonym: "inhibition of intracellular lipid transport" NARROW [] is_a: GO:0032369 ! negative regulation of lipid transport is_a: GO:0032377 ! regulation of intracellular lipid transport is_a: GO:0032387 ! negative regulation of intracellular transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0032365 ! intracellular lipid transport relationship: negatively_regulates GO:0032365 ! intracellular lipid transport [Term] id: GO:0032379 name: positive regulation of intracellular lipid transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the directed movement of lipids within cells." [GOC:mah] synonym: "activation of intracellular lipid transport" NARROW [] synonym: "stimulation of intracellular lipid transport" NARROW [] synonym: "up regulation of intracellular lipid transport" EXACT [] synonym: "up-regulation of intracellular lipid transport" EXACT [] synonym: "upregulation of intracellular lipid transport" EXACT [] is_a: GO:0032370 ! positive regulation of lipid transport is_a: GO:0032377 ! regulation of intracellular lipid transport is_a: GO:0032388 ! positive regulation of intracellular transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0032365 ! intracellular lipid transport relationship: positively_regulates GO:0032365 ! intracellular lipid transport [Term] id: GO:0032386 name: regulation of intracellular transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of substances within cells." [GOC:mah] is_a: GO:0051049 ! regulation of transport is_a: GO:0060341 ! regulation of cellular localization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0046907 ! intracellular transport relationship: regulates GO:0046907 ! intracellular transport [Term] id: GO:0032387 name: negative regulation of intracellular transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells." [GOC:mah] synonym: "down regulation of intracellular transport" EXACT [] synonym: "down-regulation of intracellular transport" EXACT [] synonym: "downregulation of intracellular transport" EXACT [] synonym: "inhibition of intracellular transport" NARROW [] is_a: GO:0032386 ! regulation of intracellular transport is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:0051051 ! negative regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0046907 ! intracellular transport relationship: negatively_regulates GO:0046907 ! intracellular transport [Term] id: GO:0032388 name: positive regulation of intracellular transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the directed movement of substances within cells." [GOC:mah] synonym: "activation of intracellular transport" NARROW [] synonym: "stimulation of intracellular transport" NARROW [] synonym: "up regulation of intracellular transport" EXACT [] synonym: "up-regulation of intracellular transport" EXACT [] synonym: "upregulation of intracellular transport" EXACT [] is_a: GO:0032386 ! regulation of intracellular transport is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:0051050 ! positive regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0046907 ! intracellular transport relationship: positively_regulates GO:0046907 ! intracellular transport [Term] id: GO:0032409 name: regulation of transporter activity namespace: biological_process def: "Any process that modulates the activity of a transporter." [GOC:mah] subset: gocheck_do_not_annotate is_a: GO:0065009 ! regulation of molecular function intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0005215 ! transporter activity relationship: regulates GO:0005215 ! transporter activity [Term] id: GO:0032410 name: negative regulation of transporter activity namespace: biological_process def: "Any process that stops or reduces the activity of a transporter." [GOC:mah] subset: gocheck_do_not_annotate synonym: "down regulation of transporter activity" EXACT [] synonym: "down-regulation of transporter activity" EXACT [] synonym: "downregulation of transporter activity" EXACT [] synonym: "inhibition of transporter activity" NARROW [] is_a: GO:0032409 ! regulation of transporter activity is_a: GO:0044092 ! negative regulation of molecular function is_a: GO:0051051 ! negative regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0005215 ! transporter activity relationship: negatively_regulates GO:0005215 ! transporter activity [Term] id: GO:0032411 name: positive regulation of transporter activity namespace: biological_process def: "Any process that activates or increases the activity of a transporter." [GOC:mah] subset: gocheck_do_not_annotate synonym: "activation of transporter activity" NARROW [] synonym: "stimulation of transporter activity" NARROW [] synonym: "up regulation of transporter activity" EXACT [] synonym: "up-regulation of transporter activity" EXACT [] synonym: "upregulation of transporter activity" EXACT [] is_a: GO:0032409 ! regulation of transporter activity is_a: GO:0044093 ! positive regulation of molecular function is_a: GO:0051050 ! positive regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0005215 ! transporter activity relationship: positively_regulates GO:0005215 ! transporter activity [Term] id: GO:0032412 name: regulation of monoatomic ion transmembrane transporter activity namespace: biological_process def: "Any process that modulates the activity of an ion transporter." [GOC:mah, GOC:tb] subset: gocheck_do_not_annotate synonym: "regulation of ion transmembrane transporter activity" BROAD [] synonym: "regulation of ion transporter activity" EXACT [GOC:tb] is_a: GO:0022898 ! regulation of transmembrane transporter activity intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0015075 ! monoatomic ion transmembrane transporter activity relationship: regulates GO:0015075 ! monoatomic ion transmembrane transporter activity [Term] id: GO:0032413 name: negative regulation of ion transmembrane transporter activity namespace: biological_process def: "Any process that stops or reduces the activity of an ion transporter." [GOC:mah, GOC:tb] subset: gocheck_do_not_annotate synonym: "down regulation of ion transporter activity" EXACT [] synonym: "down-regulation of ion transporter activity" EXACT [] synonym: "downregulation of ion transporter activity" EXACT [] synonym: "inhibition of ion transporter activity" NARROW [] synonym: "negative regulation of ion transporter activity" EXACT [GOC:tb] is_a: GO:0032410 ! negative regulation of transporter activity is_a: GO:0032412 ! regulation of monoatomic ion transmembrane transporter activity is_a: GO:0034766 ! negative regulation of monoatomic ion transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0015075 ! monoatomic ion transmembrane transporter activity relationship: negatively_regulates GO:0015075 ! monoatomic ion transmembrane transporter activity [Term] id: GO:0032414 name: positive regulation of ion transmembrane transporter activity namespace: biological_process def: "Any process that activates or increases the activity of an ion transporter." [GOC:mah, GOC:tb] subset: gocheck_do_not_annotate synonym: "activation of ion transporter activity" NARROW [] synonym: "positive regulation of ion transporter activity" EXACT [GOC:tb] synonym: "stimulation of ion transporter activity" NARROW [] synonym: "up regulation of ion transporter activity" EXACT [] synonym: "up-regulation of ion transporter activity" EXACT [] synonym: "upregulation of ion transporter activity" EXACT [] is_a: GO:0032411 ! positive regulation of transporter activity is_a: GO:0032412 ! regulation of monoatomic ion transmembrane transporter activity is_a: GO:0034767 ! positive regulation of monoatomic ion transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0015075 ! monoatomic ion transmembrane transporter activity relationship: positively_regulates GO:0015075 ! monoatomic ion transmembrane transporter activity [Term] id: GO:0032432 name: actin filament bundle namespace: cellular_component alt_id: GO:0000141 alt_id: GO:0030482 def: "An assembly of actin filaments that are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness." [GOC:mah] synonym: "actin cable" RELATED [GOC:mah] is_a: GO:0110165 ! cellular anatomical entity relationship: has_part GO:0005884 ! actin filament relationship: part_of GO:0015629 ! actin cytoskeleton [Term] id: GO:0032501 name: multicellular organismal process namespace: biological_process alt_id: GO:0044707 alt_id: GO:0050874 def: "Any biological process, occurring at the level of a multicellular organism, pertinent to its function." [GOC:curators, GOC:dph, GOC:isa_complete, GOC:tb] subset: gocheck_do_not_annotate subset: goslim_pir synonym: "organismal physiological process" EXACT [] synonym: "single-multicellular organism process" RELATED [] is_a: GO:0008150 ! biological process property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: jl creation_date: 2012-09-19T16:07:47Z [Term] id: GO:0032502 name: developmental process namespace: biological_process alt_id: GO:0044767 def: "A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition." [GOC:isa_complete] subset: goslim_agr subset: goslim_flybase_ribbon subset: goslim_pir synonym: "development" NARROW [] synonym: "single-organism developmental process" RELATED [] is_a: GO:0008150 ! biological process created_by: jl creation_date: 2012-12-19T12:21:31Z [Term] id: GO:0032504 name: multicellular organism reproduction namespace: biological_process def: "The biological process in which new individuals are produced by one or two multicellular organisms. The new individuals inherit some proportion of their genetic material from the parent or parents." [GOC:isa_complete, GOC:jid] subset: goslim_drosophila is_a: GO:0000003 ! reproduction is_a: GO:0032501 ! multicellular organismal process [Term] id: GO:0032528 name: microvillus organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell." [GOC:mah] synonym: "microvillus organisation" EXACT [GOC:mah] synonym: "microvillus organization and biogenesis" RELATED [GOC:mah] is_a: GO:0120036 ! plasma membrane bounded cell projection organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0005902 ! microvillus relationship: results_in_organization_of GO:0005902 ! microvillus property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0032530 name: regulation of microvillus organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus." [GOC:mah] synonym: "regulation of microvillus organisation" EXACT [GOC:mah] synonym: "regulation of microvillus organization and biogenesis" RELATED [GOC:mah] is_a: GO:0120035 ! regulation of plasma membrane bounded cell projection organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0032528 ! microvillus organization relationship: regulates GO:0032528 ! microvillus organization [Term] id: GO:0032534 name: regulation of microvillus assembly namespace: biological_process def: "A process that modulates the formation of a microvillus." [GOC:mah] synonym: "regulation of microvillus biogenesis" RELATED [GOC:mah] is_a: GO:0032530 ! regulation of microvillus organization is_a: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030033 ! microvillus assembly relationship: regulates GO:0030033 ! microvillus assembly [Term] id: GO:0032589 name: neuron projection membrane namespace: cellular_component def: "The portion of the plasma membrane surrounding a neuron projection." [GOC:mah] is_a: GO:0031253 ! cell projection membrane is_a: GO:0031256 ! leading edge membrane intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0043005 ! neuron projection relationship: bounding_layer_of GO:0043005 ! neuron projection relationship: part_of GO:0043005 ! neuron projection [Term] id: GO:0032594 name: protein transport within lipid bilayer namespace: biological_process def: "The directed movement of a protein from one location to another within a lipid bilayer." [GOC:mah] synonym: "protein translocation within membrane" EXACT [] synonym: "receptor translocation within membrane" NARROW [] synonym: "receptor transport within lipid bilayer" NARROW [] is_a: GO:0006886 ! intracellular protein transport is_a: GO:0061024 ! membrane organization intersection_of: GO:0015031 ! protein transport intersection_of: occurs_in GO:0016020 ! membrane relationship: occurs_in GO:0016020 ! membrane [Term] id: GO:0032774 name: RNA biosynthetic process namespace: biological_process alt_id: GO:0062103 def: "The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. Refers not only to transcription but also to e.g. viral RNA replication." [GOC:mah, GOC:txnOH] comment: Note that, in some cases, viral RNA replication and viral transcription from RNA actually refer to the same process, but may be called differently depending on the focus of a specific research study. subset: gocheck_do_not_annotate synonym: "double-stranded RNA biosynthesis" NARROW [] synonym: "double-stranded RNA biosynthetic process" NARROW [] synonym: "dsRNA biosynthesis" NARROW [] synonym: "dsRNA biosynthetic process" NARROW [GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:rl] synonym: "RNA anabolism" EXACT [] synonym: "RNA biosynthesis" EXACT [] synonym: "RNA formation" EXACT [] synonym: "RNA synthesis" EXACT [] is_a: GO:0009059 ! macromolecule biosynthetic process is_a: GO:0016070 ! RNA metabolic process is_a: GO:0034654 ! nucleobase-containing compound biosynthetic process intersection_of: GO:0009059 ! macromolecule biosynthetic process intersection_of: has_primary_output CHEBI:33697 ! ribonucleic acid relationship: has_primary_output CHEBI:33697 ! ribonucleic acid [Term] id: GO:0032782 name: bile acid secretion namespace: biological_process def: "The regulated release of bile acid, composed of any of a group of steroid carboxylic acids occurring in bile, by a cell or a tissue." [GOC:ecd] is_a: GO:0015718 ! monocarboxylic acid transport is_a: GO:0046717 ! acid secretion intersection_of: GO:0046903 ! secretion intersection_of: has_primary_input CHEBI:36235 ! bile acid anion relationship: has_primary_input CHEBI:36235 ! bile acid anion [Term] id: GO:0032787 name: monocarboxylic acid metabolic process namespace: biological_process def: "The chemical reactions and pathways involving monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-)." [GOC:vk] subset: goslim_yeast synonym: "monocarboxylate metabolic process" EXACT [] synonym: "monocarboxylic acid metabolism" EXACT [] is_a: GO:0019752 ! carboxylic acid metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:35757 ! monocarboxylic acid anion relationship: has_primary_input_or_output CHEBI:35757 ! monocarboxylic acid anion [Term] id: GO:0032790 name: ribosome disassembly namespace: biological_process def: "The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits." [GOC:mah, GOC:vk] synonym: "ribosome dissociation factor" RELATED [] synonym: "ribosome recycling" NARROW [GOC:db, PMID:9463391] is_a: GO:1903008 ! organelle disassembly intersection_of: GO:0022411 ! cellular component disassembly intersection_of: results_in_disassembly_of GO:0005840 ! ribosome relationship: results_in_disassembly_of GO:0005840 ! ribosome [Term] id: GO:0032838 name: plasma membrane bounded cell projection cytoplasm namespace: cellular_component def: "All of the contents of a plasma membrane bounded cell projection, excluding the plasma membrane surrounding the projection." [GOC:krc, GOC:mah] is_a: GO:0099568 ! cytoplasmic region intersection_of: GO:0005737 ! cytoplasm intersection_of: part_of GO:0120025 ! plasma membrane bounded cell projection relationship: part_of GO:0120025 ! plasma membrane bounded cell projection [Term] id: GO:0032868 name: response to insulin namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms." [GOC:mah, ISBN:0198506732] synonym: "response to insulin stimulus" EXACT [GOC:dos] is_a: GO:0043434 ! response to peptide hormone intersection_of: GO:0042221 ! response to chemical intersection_of: has_primary_input PR:000009054 ! insulin gene translation product relationship: has_primary_input PR:000009054 ! insulin gene translation product [Term] id: GO:0032871 name: regulation of karyogamy namespace: biological_process def: "Any process that modulates the frequency, rate or extent of karyogamy, the creation of a single nucleus from multiple nuclei as a result of membrane fusion." [GOC:mah] is_a: GO:1903353 ! regulation of nucleus organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0000741 ! karyogamy relationship: regulates GO:0000741 ! karyogamy [Term] id: GO:0032878 name: regulation of establishment or maintenance of cell polarity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns." [GOC:mah] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007163 ! establishment or maintenance of cell polarity relationship: regulates GO:0007163 ! establishment or maintenance of cell polarity [Term] id: GO:0032879 name: regulation of localization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location." [GOC:mah] synonym: "regulation of localisation" EXACT [GOC:mah] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0051179 ! localization relationship: regulates GO:0051179 ! localization [Term] id: GO:0032880 name: regulation of protein localization namespace: biological_process alt_id: GO:1903827 def: "Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location." [GOC:dph, GOC:mah, GOC:tb] subset: goslim_chembl synonym: "regulation of cellular protein localisation" EXACT [GOC:TermGenie] synonym: "regulation of cellular protein localization" EXACT [] synonym: "regulation of protein localisation" EXACT [GOC:mah] is_a: GO:0060341 ! regulation of cellular localization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0008104 ! protein localization relationship: regulates GO:0008104 ! protein localization property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22021" xsd:anyURI created_by: jl creation_date: 2015-01-20T14:32:14Z [Term] id: GO:0032881 name: regulation of polysaccharide metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving polysaccharides." [GOC:mah] is_a: GO:0006109 ! regulation of carbohydrate metabolic process is_a: GO:0060255 ! regulation of macromolecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0005976 ! polysaccharide metabolic process relationship: regulates GO:0005976 ! polysaccharide metabolic process [Term] id: GO:0032882 name: regulation of chitin metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chitin." [GOC:mah] synonym: "regulation of chitin metabolism" EXACT [] is_a: GO:0032881 ! regulation of polysaccharide metabolic process is_a: GO:0051171 ! regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006030 ! chitin metabolic process relationship: regulates GO:0006030 ! chitin metabolic process [Term] id: GO:0032883 name: regulation of chitin biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chitin." [GOC:mah] synonym: "regulation of chitin anabolism" EXACT [] synonym: "regulation of chitin biosynthesis" RELATED [] synonym: "regulation of chitin formation" EXACT [] synonym: "regulation of chitin synthesis" EXACT [] is_a: GO:0032882 ! regulation of chitin metabolic process is_a: GO:0032885 ! regulation of polysaccharide biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006031 ! chitin biosynthetic process relationship: regulates GO:0006031 ! chitin biosynthetic process [Term] id: GO:0032885 name: regulation of polysaccharide biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides." [GOC:mah] is_a: GO:0010556 ! regulation of macromolecule biosynthetic process is_a: GO:0032881 ! regulation of polysaccharide metabolic process is_a: GO:0043255 ! regulation of carbohydrate biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0000271 ! polysaccharide biosynthetic process relationship: regulates GO:0000271 ! polysaccharide biosynthetic process [Term] id: GO:0032886 name: regulation of microtubule-based process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton." [GOC:mah] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007017 ! microtubule-based process relationship: regulates GO:0007017 ! microtubule-based process [Term] id: GO:0032890 name: regulation of organic acid transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0015849 ! organic acid transport relationship: regulates GO:0015849 ! organic acid transport [Term] id: GO:0032891 name: negative regulation of organic acid transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] synonym: "down regulation of organic acid transport" EXACT [] synonym: "down-regulation of organic acid transport" EXACT [] synonym: "downregulation of organic acid transport" EXACT [] synonym: "inhibition of organic acid transport" NARROW [] is_a: GO:0032890 ! regulation of organic acid transport is_a: GO:0051051 ! negative regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0015849 ! organic acid transport relationship: negatively_regulates GO:0015849 ! organic acid transport [Term] id: GO:0032892 name: positive regulation of organic acid transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] synonym: "activation of organic acid transport" NARROW [] synonym: "stimulation of organic acid transport" NARROW [] synonym: "up regulation of organic acid transport" EXACT [] synonym: "up-regulation of organic acid transport" EXACT [] synonym: "upregulation of organic acid transport" EXACT [] is_a: GO:0032890 ! regulation of organic acid transport is_a: GO:0051050 ! positive regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0015849 ! organic acid transport relationship: positively_regulates GO:0015849 ! organic acid transport [Term] id: GO:0032940 name: secretion by cell namespace: biological_process def: "The controlled release of a substance by a cell." [GOC:mah] synonym: "cellular secretion" EXACT [] xref: Wikipedia:Secretion is_a: GO:0046903 ! secretion is_a: GO:0140352 ! export from cell [Term] id: GO:0032941 name: secretion by tissue namespace: biological_process def: "The controlled release of a substance by a tissue." [GOC:mah] synonym: "expulsion of gland contents" RELATED [GOC:mah] synonym: "tissue secretion" EXACT [] is_a: GO:0032501 ! multicellular organismal process is_a: GO:0046903 ! secretion [Term] id: GO:0032943 name: mononuclear cell proliferation namespace: biological_process def: "The expansion of a mononuclear cell population by cell division. A mononuclear cell is a leukocyte with a single non-segmented nucleus in the mature form." [GOC:add] synonym: "PBMC proliferation" NARROW [] synonym: "peripheral blood mononuclear cell proliferation" NARROW [] is_a: GO:0070661 ! leukocyte proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000842 ! mononuclear cell relationship: acts_on_population_of CL:0000842 ! mononuclear cell [Term] id: GO:0032944 name: regulation of mononuclear cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mononuclear cell proliferation." [GOC:add] synonym: "regulation of PBMC proliferation" NARROW [] synonym: "regulation of peripheral blood mononuclear cell proliferation" NARROW [] is_a: GO:0070663 ! regulation of leukocyte proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0032943 ! mononuclear cell proliferation relationship: regulates GO:0032943 ! mononuclear cell proliferation [Term] id: GO:0032945 name: negative regulation of mononuclear cell proliferation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of mononuclear cell proliferation." [GOC:add] synonym: "negative regulation of PBMC proliferation" NARROW [] synonym: "negative regulation of peripheral blood mononuclear cell proliferation" NARROW [] is_a: GO:0032944 ! regulation of mononuclear cell proliferation is_a: GO:0070664 ! negative regulation of leukocyte proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0032943 ! mononuclear cell proliferation relationship: negatively_regulates GO:0032943 ! mononuclear cell proliferation [Term] id: GO:0032946 name: positive regulation of mononuclear cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mononuclear cell proliferation." [GOC:add] synonym: "activation of mononuclear cell proliferation" NARROW [] synonym: "positive regulation of PBMC proliferation" NARROW [] synonym: "positive regulation of peripheral blood mononuclear cell proliferation" NARROW [] synonym: "stimulation of mononuclear cell proliferation" NARROW [] synonym: "up regulation of mononuclear cell proliferation" EXACT [] synonym: "up-regulation of mononuclear cell proliferation" EXACT [] synonym: "upregulation of mononuclear cell proliferation" EXACT [] is_a: GO:0032944 ! regulation of mononuclear cell proliferation is_a: GO:0070665 ! positive regulation of leukocyte proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0032943 ! mononuclear cell proliferation relationship: positively_regulates GO:0032943 ! mononuclear cell proliferation [Term] id: GO:0032956 name: regulation of actin cytoskeleton organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins." [GOC:mah] synonym: "regulation of actin cytoskeleton organisation" EXACT [GOC:mah] synonym: "regulation of actin cytoskeleton organization and biogenesis" RELATED [GOC:mah] is_a: GO:0032970 ! regulation of actin filament-based process is_a: GO:0051493 ! regulation of cytoskeleton organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030036 ! actin cytoskeleton organization relationship: regulates GO:0030036 ! actin cytoskeleton organization [Term] id: GO:0032963 name: collagen metabolic process namespace: biological_process def: "The chemical reactions and pathways involving collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%)." [GOC:mah, ISBN:0198506732] synonym: "collagen metabolism" EXACT [] is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output GO:0005581 ! collagen trimer relationship: has_primary_input_or_output GO:0005581 ! collagen trimer [Term] id: GO:0032964 name: collagen biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%)." [GOC:mah, ISBN:0198506732] synonym: "collagen anabolism" EXACT [] synonym: "collagen biosynthesis" EXACT [] synonym: "collagen formation" EXACT [] synonym: "collagen synthesis" EXACT [] is_a: GO:0009058 ! biosynthetic process is_a: GO:0032963 ! collagen metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output GO:0005581 ! collagen trimer relationship: has_primary_output GO:0005581 ! collagen trimer [Term] id: GO:0032965 name: regulation of collagen biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." [GOC:mah] synonym: "regulation of collagen anabolism" EXACT [] synonym: "regulation of collagen biosynthesis" EXACT [] synonym: "regulation of collagen formation" EXACT [] synonym: "regulation of collagen synthesis" EXACT [] is_a: GO:0009889 ! regulation of biosynthetic process is_a: GO:0010712 ! regulation of collagen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0032964 ! collagen biosynthetic process relationship: regulates GO:0032964 ! collagen biosynthetic process [Term] id: GO:0032966 name: negative regulation of collagen biosynthetic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." [GOC:mah] synonym: "negative regulation of collagen anabolism" EXACT [] synonym: "negative regulation of collagen biosynthesis" EXACT [] synonym: "negative regulation of collagen formation" EXACT [] synonym: "negative regulation of collagen synthesis" EXACT [] is_a: GO:0009890 ! negative regulation of biosynthetic process is_a: GO:0010713 ! negative regulation of collagen metabolic process is_a: GO:0032965 ! regulation of collagen biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0032964 ! collagen biosynthetic process relationship: negatively_regulates GO:0032964 ! collagen biosynthetic process [Term] id: GO:0032967 name: positive regulation of collagen biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." [GOC:mah] synonym: "positive regulation of collagen anabolism" EXACT [] synonym: "positive regulation of collagen biosynthesis" EXACT [] synonym: "positive regulation of collagen formation" EXACT [] synonym: "positive regulation of collagen synthesis" EXACT [] is_a: GO:0009891 ! positive regulation of biosynthetic process is_a: GO:0010714 ! positive regulation of collagen metabolic process is_a: GO:0032965 ! regulation of collagen biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0032964 ! collagen biosynthetic process relationship: positively_regulates GO:0032964 ! collagen biosynthetic process [Term] id: GO:0032970 name: regulation of actin filament-based process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the actin cytoskeleton." [GOC:mah] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030029 ! actin filament-based process relationship: regulates GO:0030029 ! actin filament-based process [Term] id: GO:0032984 name: protein-containing complex disassembly namespace: biological_process alt_id: GO:0034623 alt_id: GO:0043241 alt_id: GO:0043624 def: "The disaggregation of a protein-containing macromolecular complex into its constituent components." [GOC:mah] synonym: "cellular macromolecule complex disassembly" RELATED [] synonym: "cellular protein complex disassembly" RELATED [] synonym: "macromolecule complex disassembly" RELATED [] synonym: "protein complex disassembly" EXACT [] is_a: GO:0022411 ! cellular component disassembly is_a: GO:0043933 ! protein-containing complex organization intersection_of: GO:0022411 ! cellular component disassembly intersection_of: results_in_disassembly_of GO:0032991 ! protein-containing complex relationship: results_in_disassembly_of GO:0032991 ! protein-containing complex property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22580" xsd:anyURI [Term] id: GO:0032986 name: protein-DNA complex disassembly namespace: biological_process def: "The disaggregation of a protein-DNA complex into its constituent components." [GOC:mah] synonym: "DNA-protein complex disassembly" EXACT [GOC:mah] is_a: GO:0032984 ! protein-containing complex disassembly is_a: GO:0071824 ! protein-DNA complex organization intersection_of: GO:0022411 ! cellular component disassembly intersection_of: results_in_disassembly_of GO:0032993 ! protein-DNA complex relationship: results_in_disassembly_of GO:0032993 ! protein-DNA complex [Term] id: GO:0032988 name: protein-RNA complex disassembly namespace: biological_process def: "The disaggregation of a protein-RNA complex into its constituent components." [GOC:mah] synonym: "ribonucleoprotein complex disassembly" EXACT [] synonym: "RNA-protein complex disassembly" EXACT [] synonym: "RNP complex disassembly" EXACT [] is_a: GO:0032984 ! protein-containing complex disassembly is_a: GO:0071826 ! protein-RNA complex organization intersection_of: GO:0022411 ! cellular component disassembly intersection_of: results_in_disassembly_of GO:1990904 ! ribonucleoprotein complex relationship: results_in_disassembly_of GO:1990904 ! ribonucleoprotein complex property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/25143" xsd:anyURI [Term] id: GO:0032989 name: cellular anatomical entity morphogenesis namespace: biological_process def: "The process in which a cellular entity is generated and organized. A cellular entity has granularity above the level of a protein complex but below that of an anatomical system." [GOC:dph, GOC:mah, GOC:tb] subset: goslim_pir synonym: "cellular component morphogenesis" EXACT [] synonym: "cellular structure morphogenesis" EXACT [GOC:dph, GOC:tb] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of GO:0110165 ! cellular anatomical entity relationship: results_in_morphogenesis_of GO:0110165 ! cellular anatomical entity property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/25496" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26249" xsd:anyURI [Term] id: GO:0032991 name: protein-containing complex namespace: cellular_component alt_id: GO:0043234 def: "A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together." [GOC:dos, GOC:mah] comment: A protein complex in this context is meant as a stable set of interacting proteins which can be co-purified by an acceptable method, and where the complex has been shown to exist as an isolated, functional unit in vivo. Acceptable experimental methods include stringent protein purification followed by detection of protein interaction. The following methods should be considered non-acceptable: simple immunoprecipitation, pull-down experiments from cell extracts without further purification, colocalization and 2-hybrid screening. Interactions that should not be captured as protein complexes include: 1) enzyme/substrate, receptor/ligand or any similar transient interactions, unless these are a critical part of the complex assembly or are required e.g. for the receptor to be functional; 2) proteins associated in a pull-down/co-immunoprecipitation assay with no functional link or any evidence that this is a defined biological entity rather than a loose-affinity complex; 3) any complex where the only evidence is based on genetic interaction data; 4) partial complexes, where some subunits (e.g. transmembrane ones) cannot be expressed as recombinant proteins and are excluded from experiments (in this case, independent evidence is necessary to find out the composition of the full complex, if known). Interactions that may be captured as protein complexes include: 1) enzyme/substrate or receptor/ligand if the complex can only assemble and become functional in the presence of both classes of subunits; 2) complexes where one of the members has not been shown to be physically linked to the other(s), but is a homologue of, and has the same functionality as, a protein that has been experimentally demonstrated to form a complex with the other member(s); 3) complexes whose existence is accepted based on localization and pharmacological studies, but for which experimental evidence is not yet available for the complex as a whole. subset: goslim_agr subset: goslim_chembl subset: goslim_flybase_ribbon subset: goslim_mouse subset: goslim_pir synonym: "macromolecular complex" EXACT [] synonym: "macromolecule complex" EXACT [] synonym: "protein complex" NARROW [] synonym: "protein containing complex" EXACT [] synonym: "protein-protein complex" NARROW [] is_a: GO:0005575 ! cellular_component is_a: PR:000050567 ! protein-containing material entity disjoint_from: GO:0110165 ! cellular anatomical entity [Term] id: GO:0032993 name: protein-DNA complex namespace: cellular_component def: "A macromolecular complex containing both protein and DNA molecules." [GOC:mah] comment: Note that this term is intended to classify complexes that have DNA as one of the members of the complex, that is, the complex does not exist if DNA is not present. Protein complexes that interact with DNA e.g. transcription factor complexes should not be classified here. subset: goslim_pir synonym: "DNA-protein complex" EXACT [GOC:mah] is_a: GO:0032991 ! protein-containing complex relationship: has_part CHEBI:16991 ! deoxyribonucleic acid [Term] id: GO:0033002 name: muscle cell proliferation namespace: biological_process def: "The expansion of a muscle cell population by cell division." [CL:0000187, GOC:mah] synonym: "myocyte proliferation" EXACT [] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000187 ! muscle cell relationship: acts_on_population_of CL:0000187 ! muscle cell [Term] id: GO:0033013 name: tetrapyrrole metabolic process namespace: biological_process def: "The chemical reactions and pathways involving tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next." [GOC:mah] subset: goslim_pombe subset: goslim_prokaryote synonym: "tetrapyrrole metabolism" EXACT [] is_a: GO:0006725 ! cellular aromatic compound metabolic process is_a: GO:0046483 ! heterocycle metabolic process is_a: GO:1901360 ! organic cyclic compound metabolic process is_a: GO:1901564 ! organonitrogen compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:26932 ! tetrapyrrole relationship: has_primary_input_or_output CHEBI:26932 ! tetrapyrrole [Term] id: GO:0033014 name: tetrapyrrole biosynthetic process namespace: biological_process def: "The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next." [GOC:mah] synonym: "tetrapyrrole anabolism" EXACT [] synonym: "tetrapyrrole biosynthesis" EXACT [] synonym: "tetrapyrrole formation" EXACT [] synonym: "tetrapyrrole synthesis" EXACT [] is_a: GO:0018130 ! heterocycle biosynthetic process is_a: GO:0019438 ! aromatic compound biosynthetic process is_a: GO:0033013 ! tetrapyrrole metabolic process is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process is_a: GO:1901362 ! organic cyclic compound biosynthetic process is_a: GO:1901566 ! organonitrogen compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:26932 ! tetrapyrrole relationship: has_primary_output CHEBI:26932 ! tetrapyrrole [Term] id: GO:0033015 name: tetrapyrrole catabolic process namespace: biological_process def: "The chemical reactions and pathways leading to the breakdown of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next." [GOC:mah] synonym: "tetrapyrrole breakdown" EXACT [] synonym: "tetrapyrrole catabolism" EXACT [] synonym: "tetrapyrrole degradation" EXACT [] is_a: GO:0019439 ! aromatic compound catabolic process is_a: GO:0033013 ! tetrapyrrole metabolic process is_a: GO:0044270 ! cellular nitrogen compound catabolic process is_a: GO:0046700 ! heterocycle catabolic process is_a: GO:1901361 ! organic cyclic compound catabolic process is_a: GO:1901565 ! organonitrogen compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:26932 ! tetrapyrrole relationship: has_primary_input CHEBI:26932 ! tetrapyrrole [Term] id: GO:0033028 name: myeloid cell apoptotic process namespace: biological_process def: "Any apoptotic process in a myeloid cell, a cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage." [CL:0000763, GOC:add, GOC:mtg_apoptosis, PMID:11292031, PMID:15330259, PMID:17133093] synonym: "apoptosis of myeloid cells" EXACT [] synonym: "myeloid cell apoptosis" NARROW [] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000763 ! myeloid cell relationship: occurs_in CL:0000763 ! myeloid cell [Term] id: GO:0033032 name: regulation of myeloid cell apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of myeloid cell apoptotic process." [GOC:add, GOC:mtg_apoptosis] synonym: "regulation of myeloid cell apoptosis" NARROW [] is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0033028 ! myeloid cell apoptotic process relationship: regulates GO:0033028 ! myeloid cell apoptotic process [Term] id: GO:0033033 name: negative regulation of myeloid cell apoptotic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of a myeloid cell apoptotic process." [GOC:add, GOC:mtg_apoptosis] synonym: "down regulation of myeloid cell apoptosis" EXACT [] synonym: "down-regulation of myeloid cell apoptosis" EXACT [] synonym: "downregulation of myeloid cell apoptosis" EXACT [] synonym: "inhibition of myeloid cell apoptosis" NARROW [] synonym: "negative regulation of myeloid cell apoptosis" NARROW [] is_a: GO:0033032 ! regulation of myeloid cell apoptotic process is_a: GO:0043066 ! negative regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0033028 ! myeloid cell apoptotic process relationship: negatively_regulates GO:0033028 ! myeloid cell apoptotic process [Term] id: GO:0033034 name: positive regulation of myeloid cell apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of myeloid cell apoptotic process." [GOC:add, GOC:mtg_apoptosis] synonym: "activation of myeloid cell apoptosis" NARROW [] synonym: "positive regulation of myeloid cell apoptosis" NARROW [] synonym: "stimulation of myeloid cell apoptosis" NARROW [] synonym: "up regulation of myeloid cell apoptosis" EXACT [] synonym: "up-regulation of myeloid cell apoptosis" EXACT [] synonym: "upregulation of myeloid cell apoptosis" EXACT [] is_a: GO:0033032 ! regulation of myeloid cell apoptotic process is_a: GO:0043065 ! positive regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0033028 ! myeloid cell apoptotic process relationship: positively_regulates GO:0033028 ! myeloid cell apoptotic process [Term] id: GO:0033036 name: macromolecule localization namespace: biological_process def: "Any process in which a macromolecule is transported to, or maintained in, a specific location." [GOC:mah] subset: goslim_flybase_ribbon synonym: "macromolecule localisation" EXACT [GOC:mah] is_a: GO:0051179 ! localization [Term] id: GO:0033037 name: polysaccharide localization namespace: biological_process def: "Any process in which a polysaccharide is transported to, or maintained in, a specific location." [GOC:mah] synonym: "polysaccharide localisation" EXACT [GOC:mah] is_a: GO:0033036 ! macromolecule localization intersection_of: GO:0033036 ! macromolecule localization intersection_of: has_primary_input CHEBI:18154 ! polysaccharide relationship: has_primary_input CHEBI:18154 ! polysaccharide [Term] id: GO:0033043 name: regulation of organelle organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle." [GOC:mah] subset: goslim_yeast synonym: "regulation of organelle organisation" EXACT [GOC:mah] synonym: "regulation of organelle organization and biogenesis" RELATED [GOC:mah] is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006996 ! organelle organization relationship: regulates GO:0006996 ! organelle organization [Term] id: GO:0033044 name: regulation of chromosome organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a chromosome." [GOC:mah] synonym: "regulation of chromosome organisation" EXACT [GOC:mah] synonym: "regulation of chromosome organization and biogenesis" RELATED [GOC:mah] is_a: GO:0033043 ! regulation of organelle organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0051276 ! chromosome organization relationship: regulates GO:0051276 ! chromosome organization [Term] id: GO:0033045 name: regulation of sister chromatid segregation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of sister chromatid segregation." [GOC:mah] is_a: GO:0033044 ! regulation of chromosome organization is_a: GO:0051983 ! regulation of chromosome segregation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0000819 ! sister chromatid segregation relationship: regulates GO:0000819 ! sister chromatid segregation [Term] id: GO:0033046 name: negative regulation of sister chromatid segregation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation." [GOC:mah] is_a: GO:0033045 ! regulation of sister chromatid segregation is_a: GO:0051985 ! negative regulation of chromosome segregation is_a: GO:2001251 ! negative regulation of chromosome organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0000819 ! sister chromatid segregation relationship: negatively_regulates GO:0000819 ! sister chromatid segregation [Term] id: GO:0033047 name: regulation of mitotic sister chromatid segregation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of sister chromatid segregation during mitosis." [GOC:mah] is_a: GO:0033045 ! regulation of sister chromatid segregation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0000070 ! mitotic sister chromatid segregation relationship: regulates GO:0000070 ! mitotic sister chromatid segregation [Term] id: GO:0033048 name: negative regulation of mitotic sister chromatid segregation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation during mitosis." [GOC:mah] is_a: GO:0033046 ! negative regulation of sister chromatid segregation is_a: GO:0033047 ! regulation of mitotic sister chromatid segregation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0000070 ! mitotic sister chromatid segregation relationship: negatively_regulates GO:0000070 ! mitotic sister chromatid segregation [Term] id: GO:0033059 name: cellular pigmentation namespace: biological_process def: "The deposition or aggregation of coloring matter in a cell." [GOC:mtg_MIT_16mar07] is_a: GO:0009987 ! cellular process is_a: GO:0043473 ! pigmentation [Term] id: GO:0033157 name: regulation of intracellular protein transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells." [GOC:mah] is_a: GO:0032386 ! regulation of intracellular transport is_a: GO:0051223 ! regulation of protein transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006886 ! intracellular protein transport relationship: regulates GO:0006886 ! intracellular protein transport [Term] id: GO:0033238 name: regulation of amine metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform amines." [GOC:mah] synonym: "regulation of amine metabolism" EXACT [] synonym: "regulation of cellular amine metabolic process" EXACT [] is_a: GO:0051171 ! regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0009308 ! amine metabolic process relationship: regulates GO:0009308 ! amine metabolic process [Term] id: GO:0033239 name: negative regulation of amine metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amines." [GOC:mah] synonym: "negative regulation of amine metabolism" EXACT [] synonym: "negative regulation of cellular amine metabolic process" EXACT [] is_a: GO:0033238 ! regulation of amine metabolic process is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0009308 ! amine metabolic process relationship: negatively_regulates GO:0009308 ! amine metabolic process [Term] id: GO:0033240 name: positive regulation of amine metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amines." [GOC:mah] synonym: "positive regulation of amine metabolism" EXACT [] synonym: "positive regulation of cellular amine metabolic process" EXACT [] is_a: GO:0033238 ! regulation of amine metabolic process is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0009308 ! amine metabolic process relationship: positively_regulates GO:0009308 ! amine metabolic process [Term] id: GO:0033241 name: regulation of amine catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines." [GOC:mah] synonym: "regulation of amine breakdown" EXACT [] synonym: "regulation of amine catabolism" EXACT [] synonym: "regulation of amine degradation" EXACT [] synonym: "regulation of cellular amine catabolic process" EXACT [] is_a: GO:0009894 ! regulation of catabolic process is_a: GO:0033238 ! regulation of amine metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0009310 ! amine catabolic process relationship: regulates GO:0009310 ! amine catabolic process [Term] id: GO:0033242 name: negative regulation of amine catabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines." [GOC:mah] synonym: "negative regulation of amine breakdown" EXACT [] synonym: "negative regulation of amine catabolism" EXACT [] synonym: "negative regulation of amine degradation" EXACT [] synonym: "negative regulation of cellular amine catabolic process" EXACT [] is_a: GO:0009895 ! negative regulation of catabolic process is_a: GO:0033239 ! negative regulation of amine metabolic process is_a: GO:0033241 ! regulation of amine catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0009310 ! amine catabolic process relationship: negatively_regulates GO:0009310 ! amine catabolic process [Term] id: GO:0033243 name: positive regulation of amine catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines." [GOC:mah] synonym: "positive regulation of amine breakdown" EXACT [] synonym: "positive regulation of amine catabolism" EXACT [] synonym: "positive regulation of amine degradation" EXACT [] is_a: GO:0009896 ! positive regulation of catabolic process is_a: GO:0033240 ! positive regulation of amine metabolic process is_a: GO:0033241 ! regulation of amine catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0009310 ! amine catabolic process relationship: positively_regulates GO:0009310 ! amine catabolic process [Term] id: GO:0033278 name: cell proliferation in midbrain namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population in the midbrain." [GO_REF:0000021, GOC:dgf] synonym: "cell proliferation in mesencephalon" EXACT [] synonym: "mesencepahalic cell proliferation" RELATED [] is_a: GO:0061351 ! neural precursor cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: occurs_in UBERON:0001891 ! midbrain relationship: occurs_in UBERON:0001891 ! midbrain relationship: part_of GO:0030901 ! midbrain development [Term] id: GO:0033363 name: secretory granule organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion." [GOC:mah] synonym: "secretory granule organisation" EXACT [GOC:mah] synonym: "secretory granule organization and biogenesis" RELATED [GOC:mah] is_a: GO:0016050 ! vesicle organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0030141 ! secretory granule relationship: part_of GO:0010256 ! endomembrane system organization relationship: results_in_organization_of GO:0030141 ! secretory granule [Term] id: GO:0033365 name: protein localization to organelle namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within an organelle." [GOC:mah] synonym: "protein localisation to organelle" EXACT [GOC:mah] synonym: "protein localization in organelle" EXACT [GOC:mah] is_a: GO:0008104 ! protein localization intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0043226 ! organelle relationship: has_target_end_location GO:0043226 ! organelle [Term] id: GO:0033366 name: protein localization to secretory granule namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within a secretory granule." [GOC:mah] synonym: "protein localisation in secretory granule" EXACT [GOC:mah] synonym: "protein localization in secretory granule" EXACT [] is_a: GO:0033365 ! protein localization to organelle intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0030141 ! secretory granule relationship: has_target_end_location GO:0030141 ! secretory granule [Term] id: GO:0033371 name: T cell secretory granule organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a T cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion." [GOC:mah] synonym: "T cell secretory granule organisation" EXACT [GOC:mah] synonym: "T cell secretory granule organization and biogenesis" RELATED [GOC:mah] synonym: "T lymphocyte secretory granule organization" EXACT [] synonym: "T-cell secretory granule organization" EXACT [] synonym: "T-lymphocyte secretory granule maturation" RELATED [] synonym: "T-lymphocyte secretory granule organization" EXACT [] is_a: GO:0033363 ! secretory granule organization intersection_of: GO:0016043 ! cellular component organization intersection_of: occurs_in CL:0000084 ! T cell intersection_of: results_in_organization_of GO:0030141 ! secretory granule relationship: occurs_in CL:0000084 ! T cell [Term] id: GO:0033604 name: negative regulation of catecholamine secretion namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a catecholamine." [GOC:mah] synonym: "down regulation of catecholamine secretion" EXACT [] synonym: "down-regulation of catecholamine secretion" EXACT [] synonym: "downregulation of catecholamine secretion" EXACT [] synonym: "inhibition of catecholamine secretion" NARROW [] is_a: GO:0050433 ! regulation of catecholamine secretion is_a: GO:0051953 ! negative regulation of amine transport is_a: GO:1903531 ! negative regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0050432 ! catecholamine secretion relationship: negatively_regulates GO:0050432 ! catecholamine secretion [Term] id: GO:0033605 name: positive regulation of catecholamine secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of a catecholamine." [GOC:mah] synonym: "activation of catecholamine secretion" NARROW [] synonym: "stimulation of catecholamine secretion" NARROW [] synonym: "up regulation of catecholamine secretion" EXACT [] synonym: "up-regulation of catecholamine secretion" EXACT [] synonym: "upregulation of catecholamine secretion" EXACT [] is_a: GO:0050433 ! regulation of catecholamine secretion is_a: GO:0051954 ! positive regulation of amine transport is_a: GO:1903532 ! positive regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0050432 ! catecholamine secretion relationship: positively_regulates GO:0050432 ! catecholamine secretion [Term] id: GO:0033673 name: negative regulation of kinase activity namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." [GOC:mah] subset: gocheck_do_not_annotate synonym: "down regulation of kinase activity" EXACT [] synonym: "down-regulation of kinase activity" EXACT [] synonym: "downregulation of kinase activity" EXACT [] synonym: "inhibition of kinase activity" NARROW [] synonym: "kinase inhibitor" NARROW [] is_a: GO:0042326 ! negative regulation of phosphorylation is_a: GO:0043549 ! regulation of kinase activity is_a: GO:0051348 ! negative regulation of transferase activity intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0016301 ! kinase activity relationship: negatively_regulates GO:0016301 ! kinase activity [Term] id: GO:0033674 name: positive regulation of kinase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." [GOC:mah] subset: gocheck_do_not_annotate synonym: "kinase activator" NARROW [] synonym: "stimulation of kinase activity" NARROW [] synonym: "up regulation of kinase activity" EXACT [] synonym: "up-regulation of kinase activity" EXACT [] synonym: "upregulation of kinase activity" EXACT [] is_a: GO:0042327 ! positive regulation of phosphorylation is_a: GO:0043549 ! regulation of kinase activity is_a: GO:0051347 ! positive regulation of transferase activity intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0016301 ! kinase activity relationship: positively_regulates GO:0016301 ! kinase activity [Term] id: GO:0033750 name: ribosome localization namespace: biological_process alt_id: GO:0033753 def: "A process in which a ribosome is transported to, and/or maintained in, a specific location." [GOC:mah] synonym: "establishment of ribosome localisation" RELATED [] synonym: "establishment of ribosome localization" RELATED [] synonym: "ribosome localisation" RELATED [] is_a: GO:0051640 ! organelle localization intersection_of: GO:0051179 ! localization intersection_of: has_primary_input GO:0005840 ! ribosome relationship: has_primary_input GO:0005840 ! ribosome [Term] id: GO:0033762 name: response to glucagon namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus." [GOC:sl] synonym: "response to glucagon stimulus" EXACT [GOC:dos] is_a: GO:0043434 ! response to peptide hormone intersection_of: GO:0050896 ! response to stimulus intersection_of: has_primary_input CHEBI:5391 ! glucagon relationship: has_primary_input CHEBI:5391 ! glucagon [Term] id: GO:0033993 name: response to lipid namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus." [GOC:sl] is_a: GO:0010033 ! response to organic substance intersection_of: GO:0050896 ! response to stimulus intersection_of: has_primary_input CHEBI:18059 ! lipid relationship: has_primary_input CHEBI:18059 ! lipid [Term] id: GO:0034067 name: protein localization to Golgi apparatus namespace: biological_process alt_id: GO:0000042 alt_id: GO:0072600 def: "A process in which a protein is transported to, or maintained in, a location within the Golgi apparatus." [GOC:mah] synonym: "establishment of protein localisation to Golgi" NARROW [GOC:mah] synonym: "establishment of protein localization in Golgi" NARROW [] synonym: "establishment of protein localization to Golgi" NARROW [] synonym: "establishment of protein localization to Golgi apparatus" NARROW [GOC:mah] synonym: "protein localisation in Golgi apparatus" EXACT [GOC:mah] synonym: "protein localization in Golgi apparatus" EXACT [] synonym: "protein targeting to Golgi" RELATED [] synonym: "protein-Golgi targeting" RELATED [] is_a: GO:0033365 ! protein localization to organelle intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0005794 ! Golgi apparatus relationship: has_target_end_location GO:0005794 ! Golgi apparatus created_by: mah creation_date: 2011-02-14T02:26:36Z [Term] id: GO:0034101 name: erythrocyte homeostasis namespace: biological_process def: "Any process of regulating the production and elimination of erythrocytes within an organism." [GOC:add, PMID:10694114, PMID:14754397] synonym: "RBC homeostasis" EXACT [CL:0000232] synonym: "red blood cell homeostasis" EXACT [CL:0000232] is_a: GO:0002262 ! myeloid cell homeostasis intersection_of: GO:0048872 ! homeostasis of number of cells intersection_of: acts_on_population_of CL:0000232 ! erythrocyte relationship: acts_on_population_of CL:0000232 ! erythrocyte [Term] id: GO:0034219 name: carbohydrate transmembrane transport namespace: biological_process def: "The process in which a carbohydrate is transported across a membrane." [GOC:mah] comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "carbohydrate membrane transport" EXACT [] synonym: "transmembrane carbohydrate transport" EXACT [GOC:dph, GOC:tb] is_a: GO:0008643 ! carbohydrate transport is_a: GO:0055085 ! transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:16646 ! carbohydrate intersection_of: results_in_transport_across GO:0016020 ! membrane [Term] id: GO:0034220 name: monoatomic ion transmembrane transport namespace: biological_process alt_id: GO:0099131 def: "A process in which a monoatomic ion is transported across a membrane. Monatomic ions (also called simple ions) are ions consisting of exactly one atom." [GOC:mah] comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "ATP hydrolysis coupled ion transmembrane transport" NARROW [] synonym: "ion membrane transport" EXACT [] synonym: "ion transmembrane transport" BROAD [] synonym: "transmembrane ion transport" EXACT [GOC:dph, GOC:tb] is_a: GO:0006811 ! monoatomic ion transport is_a: GO:0055085 ! transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:24867 ! monoatomic ion intersection_of: results_in_transport_across GO:0016020 ! membrane [Term] id: GO:0034242 name: negative regulation of syncytium formation by plasma membrane fusion namespace: biological_process def: "Any process that decreases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." [GOC:mah] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051129 ! negative regulation of cellular component organization is_a: GO:0060142 ! regulation of syncytium formation by plasma membrane fusion intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0000768 ! syncytium formation by plasma membrane fusion relationship: negatively_regulates GO:0000768 ! syncytium formation by plasma membrane fusion [Term] id: GO:0034248 name: regulation of amide metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amides." [GOC:mah] synonym: "regulation of amide metabolism" EXACT [] synonym: "regulation of cellular amide metabolic process" EXACT [] is_a: GO:0051171 ! regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0043603 ! amide metabolic process relationship: regulates GO:0043603 ! amide metabolic process [Term] id: GO:0034249 name: negative regulation of amide metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amides." [GOC:mah] synonym: "negative regulation of amide metabolism" EXACT [] synonym: "negative regulation of cellular amide metabolic process" EXACT [] is_a: GO:0034248 ! regulation of amide metabolic process is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0043603 ! amide metabolic process relationship: negatively_regulates GO:0043603 ! amide metabolic process [Term] id: GO:0034250 name: positive regulation of amide metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amides." [GOC:mah] synonym: "positive regulation of amide metabolism" EXACT [] synonym: "positive regulation of cellular amide metabolic process" EXACT [] is_a: GO:0034248 ! regulation of amide metabolic process is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0043603 ! amide metabolic process relationship: positively_regulates GO:0043603 ! amide metabolic process [Term] id: GO:0034251 name: regulation of amide catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides." [GOC:mah] synonym: "regulation of amide breakdown" EXACT [] synonym: "regulation of amide catabolism" EXACT [] synonym: "regulation of amide degradation" EXACT [] synonym: "regulation of cellular amide catabolic process" EXACT [] is_a: GO:0009894 ! regulation of catabolic process is_a: GO:0034248 ! regulation of amide metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0043605 ! amide catabolic process relationship: regulates GO:0043605 ! amide catabolic process [Term] id: GO:0034252 name: negative regulation of amide catabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides." [GOC:mah] synonym: "negative regulation of amide breakdown" EXACT [] synonym: "negative regulation of amide catabolism" EXACT [] synonym: "negative regulation of amide degradation" RELATED [] synonym: "negative regulation of cellular amide catabolic process" EXACT [] is_a: GO:0009895 ! negative regulation of catabolic process is_a: GO:0034249 ! negative regulation of amide metabolic process is_a: GO:0034251 ! regulation of amide catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0043605 ! amide catabolic process relationship: negatively_regulates GO:0043605 ! amide catabolic process [Term] id: GO:0034253 name: positive regulation of amide catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides." [GOC:mah] synonym: "positive regulation of amide breakdown" EXACT [] synonym: "positive regulation of amide catabolism" EXACT [] synonym: "positive regulation of amide degradation" RELATED [] synonym: "positive regulation of cellular amide catabolic process" EXACT [] is_a: GO:0009896 ! positive regulation of catabolic process is_a: GO:0034250 ! positive regulation of amide metabolic process is_a: GO:0034251 ! regulation of amide catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0043605 ! amide catabolic process relationship: positively_regulates GO:0043605 ! amide catabolic process [Term] id: GO:0034284 name: response to monosaccharide namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus." [GOC:mah] synonym: "response to monosaccharide stimulus" EXACT [GOC:dos] is_a: GO:0009743 ! response to carbohydrate intersection_of: GO:0050896 ! response to stimulus intersection_of: has_primary_input CHEBI:35381 ! monosaccharide relationship: has_primary_input CHEBI:35381 ! monosaccharide [Term] id: GO:0034329 name: cell junction assembly namespace: biological_process def: "A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a cell junction." [GOC:mah] is_a: GO:0022607 ! cellular component assembly is_a: GO:0034330 ! cell junction organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0030054 ! cell junction relationship: results_in_assembly_of GO:0030054 ! cell junction [Term] id: GO:0034330 name: cell junction organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell junction. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix." [GOC:dph, GOC:jl, GOC:mah] subset: goslim_chembl subset: goslim_generic synonym: "cell junction assembly and maintenance" EXACT [] synonym: "cell junction biogenesis" RELATED [] synonym: "cell junction organisation" EXACT [GOC:mah] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0030054 ! cell junction relationship: results_in_organization_of GO:0030054 ! cell junction [Term] id: GO:0034349 name: glial cell apoptotic process namespace: biological_process def: "Any apoptotic process in a glial cell, a non-neuronal cell of the nervous system." [CL:0000125, GOC:mtg_apoptosis, GOC:sart] synonym: "apoptosis of glia" EXACT [] synonym: "apoptosis of glial cells" EXACT [] synonym: "glia apoptosis" EXACT [] synonym: "glia programmed cell death by apoptosis" EXACT [] synonym: "glial cell apoptosis" NARROW [] synonym: "glial cell programmed cell death by apoptosis" EXACT [] synonym: "programmed cell death of glia by apoptosis" EXACT [] synonym: "programmed cell death of glial cells by apoptosis" EXACT [] synonym: "programmed cell death, glia" EXACT [] synonym: "programmed cell death, glial cells" EXACT [] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000125 ! glial cell relationship: occurs_in CL:0000125 ! glial cell [Term] id: GO:0034350 name: regulation of glial cell apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of glial cell apoptotic process." [GOC:mah, GOC:mtg_apoptosis] synonym: "regulation of glial cell apoptosis" RELATED [] is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0034349 ! glial cell apoptotic process relationship: regulates GO:0034349 ! glial cell apoptotic process [Term] id: GO:0034351 name: negative regulation of glial cell apoptotic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of glial cell apoptotic process." [GOC:mah, GOC:mtg_apoptosis] synonym: "down regulation of glial cell apoptosis" EXACT [] synonym: "down-regulation of glial cell apoptosis" EXACT [] synonym: "downregulation of glial cell apoptosis" EXACT [] synonym: "inhibition of glial cell apoptosis" NARROW [] synonym: "negative regulation of glial cell apoptosis" NARROW [] is_a: GO:0034350 ! regulation of glial cell apoptotic process is_a: GO:0043066 ! negative regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0034349 ! glial cell apoptotic process relationship: negatively_regulates GO:0034349 ! glial cell apoptotic process [Term] id: GO:0034352 name: positive regulation of glial cell apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of glial cell apoptotic process." [GOC:mah, GOC:mtg_apoptosis] synonym: "activation of glial cell apoptosis" NARROW [] synonym: "positive regulation of glial cell apoptosis" NARROW [] synonym: "stimulation of glial cell apoptosis" NARROW [] synonym: "up regulation of glial cell apoptosis" EXACT [] synonym: "up-regulation of glial cell apoptosis" EXACT [] synonym: "upregulation of glial cell apoptosis" EXACT [] is_a: GO:0034350 ! regulation of glial cell apoptotic process is_a: GO:0043065 ! positive regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0034349 ! glial cell apoptotic process relationship: positively_regulates GO:0034349 ! glial cell apoptotic process [Term] id: GO:0034390 name: smooth muscle cell apoptotic process namespace: biological_process def: "Any apoptotic process in a smooth muscle cell. Smooth muscle consists of non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels." [CL:0000192, GOC:BHF, GOC:mah, GOC:mtg_apoptosis, GOC:rl] synonym: "apoptosis of smooth muscle cells" EXACT [] synonym: "programmed cell death of smooth muscle cells by apoptosis" EXACT [] synonym: "programmed cell death, smooth muscle cells" EXACT [] synonym: "SMC apoptosis" EXACT [] synonym: "smooth muscle cell apoptosis" NARROW [] synonym: "smooth muscle cell programmed cell death by apoptosis" EXACT [] is_a: GO:0010657 ! muscle cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000192 ! smooth muscle cell relationship: occurs_in CL:0000192 ! smooth muscle cell [Term] id: GO:0034391 name: regulation of smooth muscle cell apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of smooth muscle cell apoptotic process." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl] synonym: "regulation of SMC apoptosis" EXACT [] synonym: "regulation of smooth muscle cell apoptosis" NARROW [] is_a: GO:0010660 ! regulation of muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0034390 ! smooth muscle cell apoptotic process relationship: regulates GO:0034390 ! smooth muscle cell apoptotic process [Term] id: GO:0034392 name: negative regulation of smooth muscle cell apoptotic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell apoptotic process." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl] synonym: "down regulation of smooth muscle cell apoptosis" EXACT [] synonym: "down-regulation of smooth muscle cell apoptosis" EXACT [] synonym: "downregulation of smooth muscle cell apoptosis" EXACT [] synonym: "inhibition of smooth muscle cell apoptosis" NARROW [] synonym: "negative regulation of SMC apoptosis" EXACT [] synonym: "negative regulation of smooth muscle cell apoptosis" NARROW [] is_a: GO:0010656 ! negative regulation of muscle cell apoptotic process is_a: GO:0034391 ! regulation of smooth muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0034390 ! smooth muscle cell apoptotic process relationship: negatively_regulates GO:0034390 ! smooth muscle cell apoptotic process [Term] id: GO:0034393 name: positive regulation of smooth muscle cell apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of smooth muscle cell apoptotic process." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl] synonym: "activation of smooth muscle cell apoptosis" NARROW [] synonym: "positive regulation of SMC apoptosis" EXACT [] synonym: "positive regulation of smooth muscle cell apoptosis" NARROW [] synonym: "stimulation of smooth muscle cell apoptosis" NARROW [] synonym: "up regulation of smooth muscle cell apoptosis" EXACT [] synonym: "up-regulation of smooth muscle cell apoptosis" EXACT [] synonym: "upregulation of smooth muscle cell apoptosis" EXACT [] is_a: GO:0010661 ! positive regulation of muscle cell apoptotic process is_a: GO:0034391 ! regulation of smooth muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0034390 ! smooth muscle cell apoptotic process relationship: positively_regulates GO:0034390 ! smooth muscle cell apoptotic process [Term] id: GO:0034436 name: glycoprotein transport namespace: biological_process def: "The directed movement of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:BHF, GOC:mah, GOC:rl] is_a: GO:0045184 ! establishment of protein localization is_a: GO:1901264 ! carbohydrate derivative transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:17089 ! glycoprotein relationship: has_primary_input CHEBI:17089 ! glycoprotein [Term] id: GO:0034486 name: vacuolar transmembrane transport namespace: biological_process def: "The process in which a solute is transported from one side of the vacuolar membrane to the other." [GOC:mah] comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "vacuolar membrane transport" EXACT [] is_a: GO:0055085 ! transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: results_in_transport_across GO:0016020 ! membrane intersection_of: results_in_transport_to_from_or_in GO:0005773 ! vacuole relationship: results_in_transport_to_from_or_in GO:0005773 ! vacuole [Term] id: GO:0034487 name: vacuolar amino acid transmembrane transport namespace: biological_process def: "The process in which an amino acid is transported from one side of the vacuolar membrane to the other." [GOC:mah] comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "vacuolar amino acid membrane transport" EXACT [] is_a: GO:0003333 ! amino acid transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:33709 ! amino acid intersection_of: results_in_transport_across GO:0005774 ! vacuolar membrane relationship: results_in_transport_across GO:0005774 ! vacuolar membrane [Term] id: GO:0034502 name: protein localization to chromosome namespace: biological_process def: "Any process in which a protein is transported to, or maintained at, a specific location on a chromosome." [GOC:mah] synonym: "condensin localization to chromosome" NARROW [] synonym: "protein localisation to chromosome" EXACT [GOC:mah] is_a: GO:0033365 ! protein localization to organelle intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0005694 ! chromosome relationship: has_target_end_location GO:0005694 ! chromosome [Term] id: GO:0034504 name: protein localization to nucleus namespace: biological_process alt_id: GO:0044744 def: "A process in which a protein transports or maintains the localization of another protein to the nucleus." [GOC:ecd] synonym: "protein localisation to nucleus" EXACT [GOC:mah] synonym: "protein localization in cell nucleus" EXACT [] synonym: "protein localization in nucleus" EXACT [GOC:mah] synonym: "protein targeting to nucleus" RELATED [] is_a: GO:0033365 ! protein localization to organelle intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0005634 ! nucleus relationship: has_target_end_location GO:0005634 ! nucleus creation_date: 2012-11-07T15:45:54Z [Term] id: GO:0034641 name: cellular nitrogen compound metabolic process namespace: biological_process def: "The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells." [GOC:mah] subset: gocheck_do_not_annotate subset: goslim_chembl synonym: "cellular nitrogen compound metabolism" EXACT [] is_a: GO:0006807 ! nitrogen compound metabolic process is_a: GO:0044237 ! cellular metabolic process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI [Term] id: GO:0034654 name: nucleobase-containing compound biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:mah] synonym: "nucleobase, nucleoside, nucleotide and nucleic acid anabolism" EXACT [] synonym: "nucleobase, nucleoside, nucleotide and nucleic acid biosynthesis" EXACT [] synonym: "nucleobase, nucleoside, nucleotide and nucleic acid formation" EXACT [] synonym: "nucleobase, nucleoside, nucleotide and nucleic acid synthesis" NARROW [] is_a: GO:0006139 ! nucleobase-containing compound metabolic process is_a: GO:0018130 ! heterocycle biosynthetic process is_a: GO:0019438 ! aromatic compound biosynthetic process is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process is_a: GO:1901362 ! organic cyclic compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:61120 ! nucleobase-containing molecular entity relationship: has_primary_output CHEBI:61120 ! nucleobase-containing molecular entity [Term] id: GO:0034655 name: nucleobase-containing compound catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:mah] subset: goslim_chembl synonym: "nucleobase, nucleoside, nucleotide and nucleic acid breakdown" EXACT [] synonym: "nucleobase, nucleoside, nucleotide and nucleic acid catabolic process" RELATED [GOC:dph, GOC:tb] synonym: "nucleobase, nucleoside, nucleotide and nucleic acid catabolism" EXACT [] synonym: "nucleobase, nucleoside, nucleotide and nucleic acid degradation" EXACT [] is_a: GO:0006139 ! nucleobase-containing compound metabolic process is_a: GO:0019439 ! aromatic compound catabolic process is_a: GO:0044270 ! cellular nitrogen compound catabolic process is_a: GO:0046700 ! heterocycle catabolic process is_a: GO:1901361 ! organic cyclic compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:61120 ! nucleobase-containing molecular entity relationship: has_primary_input CHEBI:61120 ! nucleobase-containing molecular entity [Term] id: GO:0034672 name: anterior/posterior pattern specification involved in pronephros development namespace: biological_process def: "The developmental process that results in the creation of defined areas or spaces within the pronephros along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate." [GOC:mah] synonym: "anterior/posterior pattern specification involved in pronephric kidney development" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0039017 ! pattern specification involved in pronephros development is_a: GO:0072098 ! anterior/posterior pattern specification involved in kidney development intersection_of: GO:0009952 ! anterior/posterior pattern specification intersection_of: part_of GO:0048793 ! pronephros development [Term] id: GO:0034762 name: regulation of transmembrane transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other." [GOC:mah] synonym: "regulation of membrane transport" EXACT [] is_a: GO:0050794 ! regulation of cellular process is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0055085 ! transmembrane transport relationship: regulates GO:0055085 ! transmembrane transport [Term] id: GO:0034763 name: negative regulation of transmembrane transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other." [GOC:mah] synonym: "down regulation of transmembrane transport" EXACT [] synonym: "down-regulation of transmembrane transport" EXACT [] synonym: "downregulation of transmembrane transport" EXACT [] synonym: "inhibition of transmembrane transport" NARROW [] synonym: "negative regulation of membrane transport" EXACT [] is_a: GO:0034762 ! regulation of transmembrane transport is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:0051051 ! negative regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0055085 ! transmembrane transport relationship: negatively_regulates GO:0055085 ! transmembrane transport [Term] id: GO:0034764 name: positive regulation of transmembrane transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other." [GOC:mah] synonym: "activation of transmembrane transport" NARROW [] synonym: "positive regulation of membrane transport" EXACT [] synonym: "stimulation of transmembrane transport" NARROW [] synonym: "up regulation of transmembrane transport" EXACT [] synonym: "up-regulation of transmembrane transport" EXACT [] synonym: "upregulation of transmembrane transport" EXACT [] is_a: GO:0034762 ! regulation of transmembrane transport is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:0051050 ! positive regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0055085 ! transmembrane transport relationship: positively_regulates GO:0055085 ! transmembrane transport [Term] id: GO:0034765 name: regulation of monoatomic ion transmembrane transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other." [GOC:mah] synonym: "regulation of ion membrane transport" EXACT [] synonym: "regulation of ion transmembrane transport" BROAD [] synonym: "regulation of transmembrane ion transport" EXACT [GOC:dph, GOC:tb] is_a: GO:0034762 ! regulation of transmembrane transport is_a: GO:0043269 ! regulation of monoatomic ion transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0034220 ! monoatomic ion transmembrane transport relationship: regulates GO:0034220 ! monoatomic ion transmembrane transport [Term] id: GO:0034766 name: negative regulation of monoatomic ion transmembrane transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other." [GOC:mah] synonym: "down regulation of transmembrane ion transport" EXACT [] synonym: "down-regulation of transmembrane ion transport" EXACT [] synonym: "downregulation of transmembrane ion transport" EXACT [] synonym: "inhibition of transmembrane ion transport" NARROW [] synonym: "negative regulation of ion membrane transport" EXACT [] synonym: "negative regulation of ion transmembrane transport" BROAD [] synonym: "negative regulation of transmembrane ion transport" EXACT [GOC:dph, GOC:tb] is_a: GO:0034763 ! negative regulation of transmembrane transport is_a: GO:0034765 ! regulation of monoatomic ion transmembrane transport is_a: GO:0043271 ! negative regulation of monoatomic ion transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0034220 ! monoatomic ion transmembrane transport relationship: negatively_regulates GO:0034220 ! monoatomic ion transmembrane transport [Term] id: GO:0034767 name: positive regulation of monoatomic ion transmembrane transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other." [GOC:mah] synonym: "activation of transmembrane ion transport" NARROW [] synonym: "positive regulation of ion membrane transport" EXACT [] synonym: "positive regulation of ion transmembrane transport" BROAD [] synonym: "positive regulation of transmembrane ion transport" EXACT [] synonym: "stimulation of transmembrane ion transport" NARROW [] synonym: "up regulation of transmembrane ion transport" EXACT [] synonym: "up-regulation of transmembrane ion transport" EXACT [] synonym: "upregulation of transmembrane ion transport" EXACT [] is_a: GO:0034764 ! positive regulation of transmembrane transport is_a: GO:0034765 ! regulation of monoatomic ion transmembrane transport is_a: GO:0043270 ! positive regulation of monoatomic ion transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0034220 ! monoatomic ion transmembrane transport relationship: positively_regulates GO:0034220 ! monoatomic ion transmembrane transport [Term] id: GO:0034769 name: basement membrane disassembly namespace: biological_process alt_id: GO:0060881 def: "The controlled breakdown of the basement membrane in the context of a normal process such as imaginal disc eversion." [GOC:sart, PMID:17301221] comment: Note that this term has no relationship to 'membrane disassembly ; GO:0030397' because the basement membrane is not a lipid bilayer. synonym: "basal lamina disassembly" RELATED [] is_a: GO:0022617 ! extracellular matrix disassembly is_a: GO:0071711 ! basement membrane organization intersection_of: GO:0022411 ! cellular component disassembly intersection_of: results_in_disassembly_of GO:0005604 ! basement membrane relationship: results_in_disassembly_of GO:0005604 ! basement membrane created_by: dph creation_date: 2009-08-13T11:27:24Z [Term] id: GO:0035019 name: somatic stem cell population maintenance namespace: biological_process def: "Any process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line." [GOC:bf, ISBN:0582227089] is_a: GO:0019827 ! stem cell population maintenance intersection_of: GO:0098727 ! maintenance of cell number intersection_of: acts_on_population_of CL:0000723 ! somatic stem cell relationship: acts_on_population_of CL:0000723 ! somatic stem cell [Term] id: GO:0035039 name: male pronucleus assembly namespace: biological_process def: "The conversion at fertilization of the inactive sperm nucleus into a male pronucleus with its chromosomes processed for the first zygotic division." [GOC:bf, PMID:11735001] synonym: "male pronucleus formation" RELATED [GOC:dph] is_a: GO:0006997 ! nucleus organization is_a: GO:0022414 ! reproductive process is_a: GO:0070925 ! organelle assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0001940 ! male pronucleus relationship: part_of GO:0007338 ! single fertilization relationship: results_in_assembly_of GO:0001940 ! male pronucleus [Term] id: GO:0035040 name: sperm nuclear envelope removal namespace: biological_process def: "Removal of the sperm nuclear envelope, allowing entry of maternal factors into the sperm nucleus." [GOC:bf, PMID:11735001] is_a: GO:0022414 ! reproductive process is_a: GO:0051081 ! nuclear membrane disassembly intersection_of: GO:0051081 ! nuclear membrane disassembly intersection_of: occurs_in CL:0000019 ! sperm relationship: occurs_in CL:0000019 ! sperm relationship: part_of GO:0035039 ! male pronucleus assembly [Term] id: GO:0035045 name: sperm plasma membrane disassembly namespace: biological_process def: "The gradual disintegration of the sperm plasma membrane following insemination. This process is seen in Drosophila after entry of the entire sperm, surrounded by its plasma membrane, into the egg." [GOC:bf, ISBN:0879694238] synonym: "sperm plasma membrane breakdown" EXACT [] synonym: "sperm plasma membrane catabolism" EXACT [] synonym: "sperm plasma membrane degradation" EXACT [] is_a: GO:0007009 ! plasma membrane organization is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0030397 ! membrane disassembly intersection_of: GO:0022411 ! cellular component disassembly intersection_of: results_in_disassembly_of GO:0097524 ! sperm plasma membrane relationship: part_of GO:0007338 ! single fertilization relationship: results_in_disassembly_of GO:0097524 ! sperm plasma membrane [Term] id: GO:0035050 name: embryonic heart tube development namespace: biological_process def: "The process whose specific outcome is the progression of the embryonic heart tube over time, from its formation to the mature structure. The heart tube forms as the heart rudiment from the heart field." [GOC:go_curators] is_a: GO:0035295 ! tube development is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004141 ! heart tube relationship: part_of GO:0007507 ! heart development relationship: part_of GO:0048568 ! embryonic organ development relationship: results_in_development_of UBERON:0004141 ! heart tube [Term] id: GO:0035051 name: cardiocyte differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell that will form part of the cardiac organ of an individual." [GOC:bf] synonym: "cardiac cell differentiation" EXACT [] synonym: "heart cell differentiation" EXACT [] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0002494 ! cardiocyte relationship: part_of GO:0007507 ! heart development relationship: results_in_acquisition_of_features_of CL:0002494 ! cardiocyte [Term] id: GO:0035082 name: axoneme assembly namespace: biological_process alt_id: GO:0035083 alt_id: GO:0035084 def: "The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements." [GOC:bf, GOC:cilia, GOC:jl, ISBN:0815316194] comment: Note that cilia and eukaryotic flagella are deemed to be equivalent. synonym: "axoneme biogenesis" RELATED [GOC:mah] synonym: "ciliary axoneme assembly" EXACT [] synonym: "cilium axoneme assembly" EXACT [] synonym: "cilium axoneme biogenesis" RELATED [GOC:mah] synonym: "flagellar axoneme assembly" EXACT [] synonym: "flagellum axoneme assembly" EXACT [] is_a: GO:0001578 ! microtubule bundle formation is_a: GO:0022607 ! cellular component assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0005930 ! axoneme relationship: part_of GO:0060271 ! cilium assembly relationship: results_in_assembly_of GO:0005930 ! axoneme [Term] id: GO:0035107 name: appendage morphogenesis namespace: biological_process def: "The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch." [ISBN:0582227089] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000026 ! appendage relationship: part_of GO:0048736 ! appendage development relationship: results_in_morphogenesis_of UBERON:0000026 ! appendage [Term] id: GO:0035112 name: genitalia morphogenesis namespace: biological_process def: "The process in which the anatomical structures of genitalia are generated and organized. The genitalia are the organs of reproduction or generation, external and internal." [GOC:bf] synonym: "genital morphogenesis" RELATED [] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000990 ! reproductive system relationship: part_of GO:0048806 ! genitalia development relationship: results_in_morphogenesis_of UBERON:0000990 ! reproductive system [Term] id: GO:0035148 name: tube formation namespace: biological_process def: "Creation of the central hole of a tube in an anatomical structure through which gases and/or liquids flow." [GOC:bf] synonym: "lumen formation in an anatomical structure" RELATED [GOC:dph, GOC:mah] synonym: "tube lumen formation" EXACT [GOC:dph, GOC:mah] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0000025 ! tube relationship: part_of GO:0035239 ! tube morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0000025 ! tube [Term] id: GO:0035190 name: syncytial nuclear migration namespace: biological_process def: "The directed movement of nuclei within the syncytial embryo of insects. These precise temporal and spatial patterns of nuclear movement are coordinated with mitotic divisons and are required during blastoderm formation to reposition dividing nuclei from the interior of the syncytial embryo to the cortex." [GOC:bf, ISBN:0879694238, PMID:8314839] is_a: GO:0007097 ! nuclear migration intersection_of: GO:0007097 ! nuclear migration intersection_of: occurs_in CL:0000228 ! multinucleate cell relationship: occurs_in CL:0000228 ! multinucleate cell relationship: part_of GO:0001700 ! embryonic development via the syncytial blastoderm [Term] id: GO:0035234 name: ectopic germ cell programmed cell death namespace: biological_process def: "Programmed cell death of an errant germ line cell that is outside the normal migratory path or ectopic to the gonad. This is an important mechanism of regulating germ cell survival within the embryo." [PMID:12814944] synonym: "programmed cell death of ectopic germ cells" EXACT [] synonym: "programmed cell death, ectopic germ cells" EXACT [] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0010623 ! programmed cell death involved in cell development intersection_of: GO:0012501 ! programmed cell death intersection_of: occurs_in CL:0000586 ! germ cell relationship: occurs_in CL:0000586 ! germ cell [Term] id: GO:0035239 name: tube morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a tube are generated and organized. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system." [GOC:bf, PMID:14624839] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000025 ! tube relationship: part_of GO:0035295 ! tube development relationship: results_in_morphogenesis_of UBERON:0000025 ! tube [Term] id: GO:0035260 name: internal genitalia morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the internal genitalia are generated and organized. The internal genitalia are the internal sex organs such as the uterine tube, the uterus and the vagina in female mammals, and the testis, seminal vesicle, ejaculatory duct and prostate in male mammals." [http://www.ndif.org/Terms/genitalia.html] is_a: GO:0035112 ! genitalia morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0004175 ! internal genitalia relationship: results_in_morphogenesis_of UBERON:0004175 ! internal genitalia [Term] id: GO:0035261 name: external genitalia morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the external genitalia are generated and organized. The external genitalia are the outer sex organs, such as the penis or vulva in mammals." [http://www.ndif.org/Terms/genitalia.html] is_a: GO:0035112 ! genitalia morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0004176 ! external genitalia relationship: results_in_morphogenesis_of UBERON:0004176 ! external genitalia [Term] id: GO:0035262 name: gonad morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the gonads are generated and organized. A gonad is an animal organ producing gametes, e.g. the testes or the ovary in mammals." [ISBN:0198612001] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000991 ! gonad relationship: part_of GO:0008406 ! gonad development relationship: results_in_morphogenesis_of UBERON:0000991 ! gonad [Term] id: GO:0035264 name: multicellular organism growth namespace: biological_process def: "The increase in size or mass of an entire multicellular organism, as opposed to cell growth." [GOC:bf, GOC:curators, GOC:dph, GOC:tb] synonym: "body growth" RELATED [] is_a: GO:0032501 ! multicellular organismal process is_a: GO:0048589 ! developmental growth intersection_of: GO:0048589 ! developmental growth intersection_of: results_in_growth_of UBERON:0000468 ! multicellular organism relationship: results_in_growth_of UBERON:0000468 ! multicellular organism [Term] id: GO:0035265 name: organ growth namespace: biological_process def: "The increase in size or mass of an organ. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that function together as to perform a specific function." [GOC:bf, ISBN:0471245208, ISBN:0721662544] is_a: GO:0032501 ! multicellular organismal process is_a: GO:0048589 ! developmental growth intersection_of: GO:0048589 ! developmental growth intersection_of: results_in_growth_of UBERON:0000062 ! organ relationship: results_in_growth_of UBERON:0000062 ! organ [Term] id: GO:0035270 name: endocrine system development namespace: biological_process def: "Progression of the endocrine system over time, from its formation to a mature structure. The endocrine system is a system of hormones and ductless glands, where the glands release hormones directly into the blood, lymph or other intercellular fluid, and the hormones circulate within the body to affect distant organs. The major glands that make up the human endocrine system are the hypothalamus, pituitary, thyroid, parathryoids, adrenals, pineal body, and the reproductive glands which include the ovaries and testes." [GOC:bf, Wikipedia:Development_of_the_endocrine_system] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000949 ! endocrine system relationship: results_in_development_of UBERON:0000949 ! endocrine system [Term] id: GO:0035272 name: exocrine system development namespace: biological_process def: "Progression of the exocrine system over time, from its formation to a mature structure. The exocrine system is a system of hormones and glands, where the glands secrete straight to a target site via ducts or tubes. The human exocrine system includes the salivary glands, sweat glands and many glands of the digestive system." [GOC:bf, Wikipedia:Exocrine_gland] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002330 ! exocrine system relationship: results_in_development_of UBERON:0002330 ! exocrine system [Term] id: GO:0035282 name: segmentation namespace: biological_process def: "The regionalization process that divides an organism or part of an organism into a series of semi-repetitive parts, or segments, often arranged along a longitudinal axis." [PMID:10611687, PMID:9706689] xref: Wikipedia:Segmentation_(biology) is_a: GO:0003002 ! regionalization [Term] id: GO:0035290 name: trunk segmentation namespace: biological_process def: "Partitioning of the blastoderm embryo into trunk segmental units. In Drosophila, the trunk segments include thoracic segments and abdominal segments A1 to A8." [PMID:1360402] is_a: GO:0035282 ! segmentation relationship: part_of GO:0007350 ! blastoderm segmentation [Term] id: GO:0035295 name: tube development namespace: biological_process def: "The process whose specific outcome is the progression of a tube over time, from its initial formation to a mature structure. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues including lung and trachea, kidney, the mammary gland, the vascular system and the gastrointestinal and urinary-genital tracts." [PMID:12526790] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000025 ! tube relationship: part_of GO:0007275 ! multicellular organism development relationship: results_in_development_of UBERON:0000025 ! tube [Term] id: GO:0035372 name: protein localization to microtubule namespace: biological_process def: "A process in which a protein is transported to, or maintained at, a microtubule." [GOC:bf, GOC:lb] synonym: "protein localisation to microtubule" EXACT [GOC:mah] is_a: GO:0072698 ! protein localization to microtubule cytoskeleton intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0005874 ! microtubule relationship: has_target_end_location GO:0005874 ! microtubule created_by: bf creation_date: 2010-03-11T11:00:56Z [Term] id: GO:0035418 name: protein localization to synapse namespace: biological_process def: "Any process in which a protein is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell." [GOC:bf] synonym: "protein localisation to synapse" EXACT [GOC:mah] is_a: GO:1902414 ! protein localization to cell junction intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0045202 ! synapse relationship: has_target_end_location GO:0045202 ! synapse created_by: bf creation_date: 2010-03-29T10:58:53Z [Term] id: GO:0035433 name: acetate transmembrane transport namespace: biological_process def: "The process in which acetate is transported across a membrane. Acetate is the 2-carbon carboxylic acid ethanoic acid." [GOC:vw] comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "acetate membrane transport" EXACT [] is_a: GO:0006846 ! acetate transport is_a: GO:1905039 ! carboxylic acid transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:30089 ! acetate intersection_of: results_in_transport_across GO:0016020 ! membrane created_by: bf creation_date: 2010-04-08T10:59:01Z [Term] id: GO:0035435 name: phosphate ion transmembrane transport namespace: biological_process def: "The process in which a phosphate is transported across a membrane." [GOC:vw] comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "phosphate ion membrane transport" EXACT [] is_a: GO:0006817 ! phosphate ion transport is_a: GO:0098661 ! inorganic anion transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:35780 ! phosphate ion intersection_of: results_in_transport_across GO:0016020 ! membrane created_by: bf creation_date: 2010-04-08T11:24:06Z [Term] id: GO:0035441 name: cell migration involved in vasculogenesis namespace: biological_process def: "The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form de novo blood vessels and tubes." [GOC:dgh] is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: part_of GO:0001570 ! vasculogenesis relationship: part_of GO:0001570 ! vasculogenesis created_by: bf creation_date: 2010-04-09T03:53:01Z [Term] id: GO:0035556 name: intracellular signal transduction namespace: biological_process alt_id: GO:0007242 alt_id: GO:0007243 alt_id: GO:0023013 alt_id: GO:0023034 def: "The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell." [GOC:bf, GOC:jl, GOC:signaling, ISBN:3527303782] subset: goslim_drosophila synonym: "intracellular signal transduction pathway" NARROW [] synonym: "intracellular signaling cascade" RELATED [GOC:signaling] synonym: "intracellular signaling pathway" RELATED [] synonym: "signal transmission via intracellular cascade" NARROW [] is_a: GO:0007165 ! signal transduction intersection_of: GO:0007165 ! signal transduction intersection_of: occurs_in GO:0005622 ! intracellular anatomical structure relationship: occurs_in GO:0005622 ! intracellular anatomical structure created_by: bf creation_date: 2010-05-14T01:14:37Z [Term] id: GO:0035592 name: establishment of protein localization to extracellular region namespace: biological_process def: "The directed movement of a protein to a specific location within the extracellular region." [GOC:bf, GOC:BHF] synonym: "establishment of protein localisation in extracellular region" EXACT [GOC:mah] synonym: "establishment of protein localization in extracellular region" EXACT [] is_a: GO:0045184 ! establishment of protein localization intersection_of: GO:0045184 ! establishment of protein localization intersection_of: has_target_end_location GO:0005576 ! extracellular region relationship: has_target_end_location GO:0005576 ! extracellular region created_by: bf creation_date: 2010-11-09T10:25:08Z [Term] id: GO:0035622 name: intrahepatic bile duct development namespace: biological_process def: "The progression of the intrahepatic bile ducts over time, from their formation to the mature structure. Intrahepatic bile ducts (bile ducts within the liver) collect bile from bile canaliculi in the liver, and connect to the extrahepatic bile ducts (bile ducts outside the liver)." [GOC:bf, PMID:20614624] synonym: "IHBD development" EXACT [PMID:20614624] synonym: "intrahepatic biliary duct development" EXACT [PMID:20614624] is_a: GO:0061009 ! common bile duct development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003704 ! intrahepatic bile duct relationship: part_of GO:0001889 ! liver development relationship: results_in_development_of UBERON:0003704 ! intrahepatic bile duct created_by: bf creation_date: 2010-12-08T04:10:50Z [Term] id: GO:0035628 name: cystic duct development namespace: biological_process def: "The progression of the cystic duct over time, from its formation to the mature structure. The cystic duct runs from the gallbladder to the common bile duct." [PMID:20614624] is_a: GO:0061009 ! common bile duct development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001152 ! cystic duct relationship: results_in_development_of UBERON:0001152 ! cystic duct created_by: bf creation_date: 2010-12-10T01:24:28Z [Term] id: GO:0035645 name: enteric smooth muscle cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the intestine." [CL:0002504, GOC:BHF] synonym: "intestinal smooth muscle cell differentiation" EXACT [CL:0002504] is_a: GO:0051145 ! smooth muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0002504 ! enteric smooth muscle cell relationship: part_of GO:0048565 ! digestive tract development relationship: results_in_acquisition_of_features_of CL:0002504 ! enteric smooth muscle cell created_by: bf creation_date: 2011-01-21T02:58:58Z [Term] id: GO:0035701 name: hematopoietic stem cell migration namespace: biological_process def: "The orderly movement of a hematopoietic stem cell from one site to another. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system." [CL:0000037, GOC:BHF, PMID:20234092] synonym: "hemopoietic stem cell migration" EXACT [CL:0000037] is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000037 ! hematopoietic stem cell relationship: results_in_movement_of CL:0000037 ! hematopoietic stem cell created_by: bf creation_date: 2011-02-28T03:20:36Z [Term] id: GO:0035725 name: sodium ion transmembrane transport namespace: biological_process def: "A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore." [GOC:vw] comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "sodium ion membrane transport" EXACT [] is_a: GO:0006814 ! sodium ion transport is_a: GO:0098655 ! monoatomic cation transmembrane transport is_a: GO:0098662 ! inorganic cation transmembrane transport intersection_of: GO:0055085 ! transmembrane transport intersection_of: has_primary_input CHEBI:29101 ! sodium(1+) created_by: bf creation_date: 2011-03-10T02:52:36Z [Term] id: GO:0035735 name: intraciliary transport involved in cilium assembly namespace: biological_process def: "The bidirectional movement of large protein complexes along microtubules within a cilium that contributes to cilium assembly." [GOC:bf, GOC:cilia, Reactome:R-HSA-5620924.2] synonym: "intraciliary transport involved in cilium morphogenesis" RELATED [] synonym: "intraflagellar transport" BROAD [] synonym: "intraflagellar transport involved in cilium morphogenesis" RELATED [] xref: Reactome:R-HSA-5620924.2 is_a: GO:0042073 ! intraciliary transport intersection_of: GO:0042073 ! intraciliary transport intersection_of: part_of GO:0060271 ! cilium assembly relationship: part_of GO:0060271 ! cilium assembly created_by: bf creation_date: 2011-03-17T10:55:42Z [Term] id: GO:0035736 name: cell proliferation involved in compound eye morphogenesis namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to compound eye morphogenesis." [GOC:bf, GOC:sart] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: part_of GO:0001745 ! compound eye morphogenesis relationship: part_of GO:0001745 ! compound eye morphogenesis created_by: bf creation_date: 2011-03-17T10:57:03Z [Term] id: GO:0035778 name: pronephric nephron tubule epithelial cell differentiation namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephric nephron tubule as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10, GOC:yaf, PMID:18787069] is_a: GO:0039014 ! cell differentiation involved in pronephros development is_a: GO:0072160 ! nephron tubule epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:1000090 ! pronephric nephron tubule epithelial cell relationship: part_of GO:0039020 ! pronephric nephron tubule development relationship: results_in_acquisition_of_features_of CL:1000090 ! pronephric nephron tubule epithelial cell created_by: bf creation_date: 2011-04-04T11:07:47Z [Term] id: GO:0035779 name: angioblast cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an angioblast cell. Angioblasts are one of the two products formed from hemangioblast cells (the other being pluripotent hemopoietic stem cells)." [CL:0000566, GOC:yaf] synonym: "angioblastic mesenchymal cell differentiation" EXACT [CL:0000566] is_a: GO:0048863 ! stem cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000566 ! angioblastic mesenchymal cell relationship: part_of GO:0001568 ! blood vessel development relationship: results_in_acquisition_of_features_of CL:0000566 ! angioblastic mesenchymal cell created_by: bf creation_date: 2011-04-04T11:10:38Z [Term] id: GO:0035787 name: cell migration involved in kidney development namespace: biological_process def: "The orderly movement of a cell from one site to another that will contribute to the progression of the kidney over time, from its formation to the mature organ." [GOC:bf, GOC:mtg_kidney_jan10, GOC:yaf] is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: part_of GO:0001822 ! kidney development relationship: part_of GO:0001822 ! kidney development created_by: bf creation_date: 2011-04-06T10:39:52Z [Term] id: GO:0035788 name: cell migration involved in metanephros development namespace: biological_process def: "The orderly movement of a cell from one site to another that will contribute to the progression of the metanephric kidney over time, from its formation to the mature organ." [GOC:bf, GOC:mtg_kidney_jan10, GOC:yaf] synonym: "cell migration involved in metanephric kidney development" EXACT [GOC:bf] is_a: GO:0035787 ! cell migration involved in kidney development intersection_of: GO:0016477 ! cell migration intersection_of: part_of GO:0001656 ! metanephros development relationship: part_of GO:0001656 ! metanephros development created_by: bf creation_date: 2011-04-06T10:42:21Z [Term] id: GO:0035799 name: ureter maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for the ureter to attain its fully functional state. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut." [GOC:bf, GOC:mtg_kidney_jan10, GOC:yaf, PMID:17881463] is_a: GO:0048799 ! animal organ maturation intersection_of: GO:0071695 ! anatomical structure maturation intersection_of: results_in_maturation_of UBERON:0000056 ! ureter relationship: part_of GO:0072189 ! ureter development relationship: results_in_maturation_of UBERON:0000056 ! ureter created_by: bf creation_date: 2011-04-14T01:13:39Z [Term] id: GO:0035805 name: egg coat namespace: cellular_component def: "A specialized extracellular matrix that surrounds the plasma membrane of the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development." [PMID:16944418, PMID:17163408] synonym: "vitelline membrane" NARROW [PMID:16944418, PMID:17163408] synonym: "zona pellucida" NARROW [PMID:16944418, PMID:17163408] is_a: GO:0031012 ! extracellular matrix intersection_of: GO:0031012 ! extracellular matrix intersection_of: part_of CL:0000025 ! egg cell relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of CL:0000025 ! egg cell created_by: bf creation_date: 2011-04-19T02:07:23Z [Term] id: GO:0035809 name: regulation of urine volume namespace: biological_process def: "Any process that modulates the amount of urine excreted from the body over a unit of time." [GOC:mtg_25march11, GOC:yaf] synonym: "regulation of urinary volume" EXACT [] synonym: "regulation of urine flow" EXACT [] is_a: GO:0003014 ! renal system process is_a: GO:0050878 ! regulation of body fluid levels created_by: bf creation_date: 2011-04-20T01:17:38Z [Term] id: GO:0035834 name: indole alkaloid metabolic process namespace: biological_process def: "The chemical reactions and pathways involving an indole alkaloid, an alkaloid containing an indole skeleton." [GOC:yaf] synonym: "indole alkaloid metabolism" EXACT [GOC:bf] is_a: GO:0009820 ! alkaloid metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:38958 ! indole alkaloid relationship: has_primary_input_or_output CHEBI:38958 ! indole alkaloid created_by: bf creation_date: 2011-05-04T03:17:44Z [Term] id: GO:0035835 name: indole alkaloid biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of an indole alkaloid, an alkaloid containing an indole skeleton." [GOC:yaf] synonym: "indole alkaloid anabolism" EXACT [GOC:bf] synonym: "indole alkaloid biosynthesis" EXACT [GOC:bf] synonym: "indole alkaloid formation" EXACT [GOC:bf] synonym: "indole alkaloid synthesis" EXACT [GOC:bf] is_a: GO:0009821 ! alkaloid biosynthetic process is_a: GO:0035834 ! indole alkaloid metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:38958 ! indole alkaloid relationship: has_primary_output CHEBI:38958 ! indole alkaloid created_by: bf creation_date: 2011-05-04T03:18:31Z [Term] id: GO:0035844 name: cloaca development namespace: biological_process def: "The process whose specific outcome is the progression of the cloaca over time, from it's formation to the mature structure. The cloaca is the common chamber into which intestinal, genital and urinary canals open in vertebrates." [GOC:dgh, ISBN:0582227089] synonym: "cloacal development" EXACT [GOC:bf] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000162 ! cloaca relationship: part_of GO:0001655 ! urogenital system development relationship: part_of GO:0048546 ! digestive tract morphogenesis relationship: results_in_development_of UBERON:0000162 ! cloaca created_by: bf creation_date: 2011-05-06T01:54:35Z [Term] id: GO:0035846 name: oviduct epithelium development namespace: biological_process def: "The progression of the oviduct epithelium over time from its initial formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism. The oviduct epithelium is the specialized epithelium that lines the oviduct." [GOC:yaf, http://www.thefreedictionary.com/oviduct] synonym: "fallopian tube epithelium development" NARROW [GOC:yaf] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004804 ! oviduct epithelium relationship: part_of GO:0060066 ! oviduct development relationship: results_in_development_of UBERON:0004804 ! oviduct epithelium created_by: bf creation_date: 2011-05-10T10:53:05Z [Term] id: GO:0035847 name: uterine epithelium development namespace: biological_process def: "The progression of an epithelium of the uterus over time from its initial formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure." [GOC:bf, GOC:yaf] synonym: "uterus epithelial development" EXACT [GOC:yaf] is_a: GO:0035846 ! oviduct epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0006955 ! uterine epithelium relationship: part_of GO:0060065 ! uterus development relationship: results_in_development_of UBERON:0006955 ! uterine epithelium created_by: bf creation_date: 2011-05-10T10:57:45Z [Term] id: GO:0035848 name: oviduct morphogenesis namespace: biological_process def: "The process in which anatomical structures of the oviduct are generated and organized. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism." [GOC:yaf, http://www.thefreedictionary.com/oviduct] synonym: "fallopian tube morphogenesis" NARROW [GOC:yaf] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0009887 ! animal organ morphogenesis is_a: GO:0035239 ! tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000993 ! oviduct relationship: part_of GO:0060066 ! oviduct development relationship: results_in_morphogenesis_of UBERON:0000993 ! oviduct created_by: bf creation_date: 2011-05-10T11:01:20Z [Term] id: GO:0035850 name: epithelial cell differentiation involved in kidney development namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an epithelial cell that characterize the cells of the kidney as it progresses from its formation to the mature state." [GOC:bf, GOC:mtg_kidney_jan10, GOC:yaf, PMID:16216236] is_a: GO:0030855 ! epithelial cell differentiation is_a: GO:0061005 ! cell differentiation involved in kidney development intersection_of: GO:0030855 ! epithelial cell differentiation intersection_of: part_of GO:0001822 ! kidney development created_by: bf creation_date: 2011-05-11T11:34:21Z [Term] id: GO:0035855 name: megakaryocyte development namespace: biological_process def: "The process whose specific outcome is the progression of a megakaryocyte cell over time, from its formation to the mature structure. Megakaryocyte development does not include the steps involved in committing a cell to a megakaryocyte fate. A megakaryocyte is a giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow." [CL:0000556, GOC:BHF, GOC:vk] synonym: "megakaryocyte cell development" EXACT [GOC:bf] is_a: GO:0061515 ! myeloid cell development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of CL:0000556 ! megakaryocyte relationship: part_of GO:0030219 ! megakaryocyte differentiation relationship: results_in_development_of CL:0000556 ! megakaryocyte created_by: bf creation_date: 2011-05-13T01:28:06Z [Term] id: GO:0035869 name: ciliary transition zone namespace: cellular_component def: "A region of the cilium between the basal body and proximal segment that is characterized by Y-shaped assemblages that connect axonemal microtubules to the ciliary membrane. The ciliary transition zone appears to function as a gate that controls ciliary membrane composition and separates the cytosol from the ciliary plasm." [GOC:cilia, GOC:kmv, PMID:21422230] comment: Depending on the species, this region may have a distinct geometrically shaped electron-dense structure within the axonemal lumen visible in electron microscopy images; most animals don't display this inner structure. The axoneme extends through the ciliary transition zone, but only consists of the outer doublets. The central pair, axonemal spokes, and dynein complexes are not found in this part of the ciliary shaft. Note that the connecting cilium of the photoreceptor cells is thought to be equivalent to the transition zone. synonym: "cilial transition zone" EXACT [] synonym: "cilium transition zone" EXACT [] synonym: "connecting cilium" RELATED [] is_a: GO:0110165 ! cellular anatomical entity relationship: part_of GO:0005929 ! cilium created_by: bf creation_date: 2011-05-25T03:09:58Z [Term] id: GO:0035883 name: enteroendocrine cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an enteroendocrine cell. Enteroendocrine cells are hormonally active epithelial cells in the gut that constitute the diffuse neuroendocrine system." [CL:0000164, GOC:bf] is_a: GO:0002067 ! glandular epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000164 ! enteroendocrine cell relationship: results_in_acquisition_of_features_of CL:0000164 ! enteroendocrine cell created_by: bf creation_date: 2011-06-06T11:48:51Z [Term] id: GO:0035886 name: vascular associated smooth muscle cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a vascular smooth muscle cell." [GOC:sl, PMID:16151017, PMID:18267954] synonym: "vascular smooth muscle cell differentiation" EXACT [] synonym: "VSMC differentiation" EXACT [PMID:16151017] is_a: GO:0051145 ! smooth muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000359 ! vascular associated smooth muscle cell relationship: part_of GO:0001944 ! vasculature development relationship: results_in_acquisition_of_features_of CL:0000359 ! vascular associated smooth muscle cell created_by: bf creation_date: 2011-06-08T11:23:52Z [Term] id: GO:0035887 name: aortic smooth muscle cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell surrounding the aorta." [GOC:sl] is_a: GO:0035886 ! vascular associated smooth muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0002539 ! aortic smooth muscle cell relationship: results_in_acquisition_of_features_of CL:0002539 ! aortic smooth muscle cell created_by: bf creation_date: 2011-06-08T11:34:26Z [Term] id: GO:0035904 name: aorta development namespace: biological_process def: "The progression of the aorta over time, from its initial formation to the mature structure. An aorta is an artery that carries blood from the heart to other parts of the body." [GOC:bf, GOC:dgh, MA:0000062, UBERON:0000947, Wikipedia:Aorta] is_a: GO:0060840 ! artery development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000947 ! aorta relationship: results_in_development_of UBERON:0000947 ! aorta created_by: bf creation_date: 2011-06-24T11:00:07Z [Term] id: GO:0035905 name: ascending aorta development namespace: biological_process def: "The progression of the ascending aorta over time, from its initial formation to the mature structure. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once." [GOC:bf, GOC:dgh, MA:0002570, UBERON:0001496, Wikipedia:Ascending_aorta] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001496 ! ascending aorta relationship: part_of GO:0035904 ! aorta development relationship: results_in_development_of UBERON:0001496 ! ascending aorta created_by: bf creation_date: 2011-06-24T11:02:01Z [Term] id: GO:0035906 name: descending aorta development namespace: biological_process def: "The progression of the descending aorta over time, from its initial formation to the mature structure. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once." [GOC:bf, GOC:dgh, MA:0002571, UBERON:0001514, Wikipedia:Descending_aorta] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001514 ! descending aorta relationship: part_of GO:0035904 ! aorta development relationship: results_in_development_of UBERON:0001514 ! descending aorta created_by: bf creation_date: 2011-06-24T11:05:22Z [Term] id: GO:0035907 name: dorsal aorta development namespace: biological_process def: "The progression of the dorsal aorta over time, from its initial formation to the mature structure. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once." [GOC:bf, GOC:dgh, UBERON:0005805, Wikipedia:Aorta, ZFA:0000014] is_a: GO:0035904 ! aorta development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005805 ! dorsal aorta relationship: results_in_development_of UBERON:0005805 ! dorsal aorta created_by: bf creation_date: 2011-06-24T11:07:01Z [Term] id: GO:0035909 name: aorta morphogenesis namespace: biological_process def: "The process in which the anatomical structures of an aorta are generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body." [GOC:bf, GOC:dgh, MA:0000062, UBERON:0000947, Wikipedia:Aorta] is_a: GO:0048844 ! artery morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000947 ! aorta relationship: part_of GO:0035904 ! aorta development relationship: results_in_morphogenesis_of UBERON:0000947 ! aorta created_by: bf creation_date: 2011-06-24T11:11:11Z [Term] id: GO:0035910 name: ascending aorta morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the ascending aorta are generated and organized. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once." [GOC:bf, GOC:dgh, MA:0002570, UBERON:0001496, Wikipedia:Ascending_aorta] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001496 ! ascending aorta relationship: part_of GO:0035905 ! ascending aorta development relationship: part_of GO:0035909 ! aorta morphogenesis relationship: results_in_morphogenesis_of UBERON:0001496 ! ascending aorta created_by: bf creation_date: 2011-06-24T11:14:52Z [Term] id: GO:0035911 name: descending aorta morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the descending aorta are generated and organized. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once." [GOC:bf, GOC:dgh, MA:0002571, UBERON:0001514, Wikipedia:Descending_aorta] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001514 ! descending aorta relationship: part_of GO:0035906 ! descending aorta development relationship: part_of GO:0035909 ! aorta morphogenesis relationship: results_in_morphogenesis_of UBERON:0001514 ! descending aorta created_by: bf creation_date: 2011-06-24T11:19:24Z [Term] id: GO:0035912 name: dorsal aorta morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the dorsal aorta are generated and organized. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once." [GOC:bf, GOC:dgh, UBERON:0005805, Wikipedia:Aorta, ZFA:0000014] is_a: GO:0035909 ! aorta morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0005805 ! dorsal aorta relationship: part_of GO:0035907 ! dorsal aorta development relationship: results_in_morphogenesis_of UBERON:0005805 ! dorsal aorta created_by: bf creation_date: 2011-06-24T11:22:14Z [Term] id: GO:0035914 name: skeletal muscle cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle cell, a somatic cell located in skeletal muscle." [CL:0000188, GOC:BHF, GOC:vk] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000188 ! cell of skeletal muscle relationship: part_of GO:0007519 ! skeletal muscle tissue development relationship: results_in_acquisition_of_features_of CL:0000188 ! cell of skeletal muscle created_by: bf creation_date: 2011-06-24T02:36:19Z [Term] id: GO:0035929 name: steroid hormone secretion namespace: biological_process def: "The regulated release of any steroid that acts as a hormone into the circulatory system." [GOC:sl] is_a: GO:0060986 ! endocrine hormone secretion is_a: GO:0140353 ! lipid export from cell intersection_of: GO:0046903 ! secretion intersection_of: has_primary_input CHEBI:26764 ! steroid hormone relationship: has_primary_input CHEBI:26764 ! steroid hormone created_by: bf creation_date: 2011-07-20T01:01:00Z [Term] id: GO:0035935 name: androgen secretion namespace: biological_process def: "The regulated release of an androgen into the circulatory system. Androgens are steroid hormones that stimulate or control the development and maintenance of masculine characteristics in vertebrates." [GOC:sl] is_a: GO:0035929 ! steroid hormone secretion created_by: bf creation_date: 2011-07-20T01:11:31Z [Term] id: GO:0035987 name: endodermal cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized features of an endoderm cell, a cell of the inner of the three germ layers of the embryo." [CL:0000223, GOC:yaf, PMID:17624332] synonym: "endoderm cell differentiation" EXACT [CL:0000223] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000223 ! endodermal cell relationship: part_of GO:0001706 ! endoderm formation relationship: results_in_acquisition_of_features_of CL:0000223 ! endodermal cell created_by: bf creation_date: 2011-08-25T04:50:36Z [Term] id: GO:0035989 name: tendon development namespace: biological_process def: "The process whose specific outcome is the progression of a tendon over time, from its formation to the mature structure. A tendon is a fibrous, strong, connective tissue that connects muscle to bone or integument and is capable of withstanding tension. Tendons and muscles work together to exert a pulling force." [GOC:yaf, PMID:21412429, UBERON:0000043] synonym: "sinew development" RELATED [UBERON:0000043] is_a: GO:0061448 ! connective tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000043 ! tendon relationship: results_in_development_of UBERON:0000043 ! tendon created_by: bf creation_date: 2011-08-26T04:14:30Z [Term] id: GO:0035992 name: tendon formation namespace: biological_process def: "The process that gives rise to a tendon. This process pertains to the initial formation of a tendon from unspecified parts." [GOC:yaf, PMID:17567668, UBERON:0000043] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0000043 ! tendon relationship: part_of GO:0035989 ! tendon development relationship: results_in_formation_of_anatomical_entity UBERON:0000043 ! tendon created_by: bf creation_date: 2011-08-30T01:35:10Z [Term] id: GO:0036072 name: direct ossification namespace: biological_process def: "The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance, that does not require the replacement of preexisting tissues." [GO_REF:0000034] is_a: GO:0001503 ! ossification created_by: bf creation_date: 2011-12-19T01:47:22Z [Term] id: GO:0036093 name: germ cell proliferation namespace: biological_process def: "The multiplication or reproduction of germ cells, reproductive cells in multicellular organisms, resulting in the expansion of a cell population." [CL:0000586, GOC:kmv] is_a: GO:0008283 ! cell population proliferation is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000586 ! germ cell relationship: acts_on_population_of CL:0000586 ! germ cell relationship: part_of GO:0007276 ! gamete generation created_by: bf creation_date: 2012-01-17T04:06:27Z [Term] id: GO:0036099 name: female germ-line stem cell population maintenance namespace: biological_process def: "The process by which an organism or tissue maintains a population of female germ-line stem cells." [GOC:sart] is_a: GO:0030718 ! germ-line stem cell population maintenance intersection_of: GO:0098727 ! maintenance of cell number intersection_of: acts_on_population_of CL:0000022 ! female germ line stem cell relationship: acts_on_population_of CL:0000022 ! female germ line stem cell created_by: bf creation_date: 2012-01-26T01:58:10Z [Term] id: GO:0036145 name: dendritic cell homeostasis namespace: biological_process def: "The process of regulating the proliferation and elimination of dendritic cells such that the total number of dendritic cells within a whole or part of an organism is stable over time in the absence of an outside stimulus." [CL:0000451, GOC:uh, PMID:12570827, PMID:19176316] synonym: "DC homeostasis" RELATED [PMID:19176316] is_a: GO:0001776 ! leukocyte homeostasis intersection_of: GO:0048872 ! homeostasis of number of cells intersection_of: acts_on_population_of CL:0000451 ! dendritic cell relationship: acts_on_population_of CL:0000451 ! dendritic cell created_by: bf creation_date: 2012-03-12T11:05:36Z [Term] id: GO:0036194 name: muscle cell projection namespace: cellular_component def: "A prolongation or process extending from a muscle cell. A muscle cell is a mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns." [CL:0000187, GOC:kmv, PMID:15930100, PMID:22464329] synonym: "muscle arm" NARROW [GOC:kmv] synonym: "myocyte projection" EXACT [CL:0000187] synonym: "myopodia" NARROW [GOC:kmv] is_a: GO:0120025 ! plasma membrane bounded cell projection is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: GO:0120025 ! plasma membrane bounded cell projection intersection_of: part_of CL:0000187 ! muscle cell relationship: part_of CL:0000187 ! muscle cell created_by: bf creation_date: 2012-04-20T10:20:47Z [Term] id: GO:0036195 name: muscle cell projection membrane namespace: cellular_component def: "The portion of the plasma membrane surrounding a muscle cell projection." [CL:0000187, GOC:kmv, PMID:15930100, PMID:22464329] is_a: GO:0031253 ! cell projection membrane is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: GO:0031253 ! cell projection membrane intersection_of: part_of GO:0036194 ! muscle cell projection relationship: part_of GO:0036194 ! muscle cell projection created_by: bf creation_date: 2012-04-20T10:21:51Z [Term] id: GO:0036293 name: response to decreased oxygen levels namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen." [GOC:al] comment: This term should be used when a decrease in oxygen levels is not considered a stress response. For a hypoxic stress response, consider instead 'response to hypoxia ; GO:0001666'. synonym: "response to lowered oxygen levels" EXACT [GOC:bf] is_a: GO:0070482 ! response to oxygen levels created_by: bf creation_date: 2012-07-20T01:05:46Z [Term] id: GO:0036304 name: umbilical cord morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the umbilical cord are generated and organized. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta." [GOC:BHF, GOC:gr, PMID:15107403] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002331 ! umbilical cord relationship: part_of GO:0061027 ! umbilical cord development relationship: results_in_morphogenesis_of UBERON:0002331 ! umbilical cord created_by: bf creation_date: 2012-08-08T10:12:11Z [Term] id: GO:0036333 name: hepatocyte homeostasis namespace: biological_process def: "Any biological process involved in the maintenance of the steady-state number of hepatocytes within a population of cells. Hepatocytes are specialized epithelial cells of the liver that are organized into interconnected plates called lobules." [CL:0000182, GOC:nhn, PMID:19878874] is_a: GO:0048872 ! homeostasis of number of cells intersection_of: GO:0048872 ! homeostasis of number of cells intersection_of: acts_on_population_of CL:0000182 ! hepatocyte relationship: acts_on_population_of CL:0000182 ! hepatocyte created_by: bf creation_date: 2012-09-05T10:17:07Z [Term] id: GO:0036334 name: epidermal stem cell homeostasis namespace: biological_process def: "Any biological process involved in the maintenance of the steady-state number of epidermal stem cells within a population of cells." [CL:1000428, GOC:nhn, PMID:17666529] is_a: GO:0048872 ! homeostasis of number of cells intersection_of: GO:0048872 ! homeostasis of number of cells intersection_of: acts_on_population_of CL:1000428 ! stem cell of epidermis relationship: acts_on_population_of CL:1000428 ! stem cell of epidermis created_by: bf creation_date: 2012-09-05T10:21:23Z [Term] id: GO:0036336 name: dendritic cell migration namespace: biological_process def: "The movement of a dendritic cell within or between different tissues and organs of the body." [CL:0000451, GOC:nhn, PMID:19339990] is_a: GO:0071674 ! mononuclear cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000451 ! dendritic cell relationship: results_in_movement_of CL:0000451 ! dendritic cell created_by: bf creation_date: 2012-09-05T10:24:46Z [Term] id: GO:0036342 name: post-anal tail morphogenesis namespace: biological_process def: "The process in which a post-anal tail is generated and organized. A post-anal tail is a muscular region of the body that extends posterior to the anus. The post-anal tail may aid locomotion and balance." [GOC:bf, GOC:kmv, Wikipedia:Chordate] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0007812 ! post-anal tail relationship: in_taxon NCBITaxon:7711 {all_only="true"} ! Chordata relationship: only_in_taxon NCBITaxon:7711 ! Chordata relationship: results_in_morphogenesis_of UBERON:0007812 ! post-anal tail created_by: bf creation_date: 2012-09-11T13:54:49Z [Term] id: GO:0036477 name: somatodendritic compartment namespace: cellular_component def: "The region of a neuron that includes the cell body (cell soma) and dendrite(s), but excludes the axon." [GOC:pad, GOC:PARL] is_a: GO:0110165 ! cellular anatomical entity relationship: part_of CL:0000540 ! neuron created_by: bf creation_date: 2014-07-24T10:06:19Z [Term] id: GO:0036484 name: trunk neural crest cell migration namespace: biological_process def: "The characteristic movement of trunk neural crest cells from the neural tube to other locations in the vertebrate embryo." [GOC:bf, GOC:mat, GOC:PARL, PMID:2387238] synonym: "trunk NCC migration" EXACT [PMID:2387238] is_a: GO:0001755 ! neural crest cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000011 ! migratory trunk neural crest cell relationship: part_of GO:0035290 ! trunk segmentation relationship: results_in_movement_of CL:0000011 ! migratory trunk neural crest cell created_by: bf creation_date: 2014-08-26T15:27:44Z [Term] id: GO:0036504 name: Golgi membrane fusion namespace: biological_process def: "The joining of two lipid bilayers that surround the Golgi apparatus to form a single Golgi membrane." [GOC:bf, GOC:PARL, PMID:12473691] synonym: "Golgi apparatus membrane fusion" EXACT [] synonym: "membrane fusion involved in Golgi reassembly" EXACT [GOC:bf] synonym: "post-mitotic fusion of Golgi membranes" EXACT [PMID:10811609] is_a: GO:0090174 ! organelle membrane fusion intersection_of: GO:0061025 ! membrane fusion intersection_of: results_in_fusion_of GO:0000139 ! Golgi membrane relationship: part_of GO:0090168 ! Golgi reassembly relationship: results_in_fusion_of GO:0000139 ! Golgi membrane created_by: bf creation_date: 2015-05-21T10:05:06Z [Term] id: GO:0039006 name: pronephric nephron tubule formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a pronephric nephron tubule from unspecified parts. A pronephric nephron tubule is an epithelial tube that is part of a nephron in the pronephros." [GOC:mtg_kidney_jan10] synonym: "pronephric tubule formation" EXACT [GOC:mtg_kidney_jan10] synonym: "pronephros tubule formation" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0072079 ! nephron tubule formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0005310 ! pronephric nephron tubule relationship: part_of GO:0039008 ! pronephric nephron tubule morphogenesis relationship: part_of GO:0072116 ! pronephros formation relationship: results_in_formation_of_anatomical_entity UBERON:0005310 ! pronephric nephron tubule created_by: bf creation_date: 2010-07-02T09:37:27Z [Term] id: GO:0039007 name: pronephric nephron morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the pronephric nephron are generated and organized. A pronephric nephron is the functional unit of the pronephros." [GOC:mtg_kidney_jan10] is_a: GO:0072028 ! nephron morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0005309 ! pronephric nephron relationship: part_of GO:0039019 ! pronephric nephron development relationship: part_of GO:0072114 ! pronephros morphogenesis relationship: results_in_morphogenesis_of UBERON:0005309 ! pronephric nephron created_by: bf creation_date: 2010-07-02T09:38:53Z [Term] id: GO:0039008 name: pronephric nephron tubule morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a pronephric nephron tubule are generated and organized from an epithelium. A pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron." [GOC:mtg_kidney_jan10, ZFA:00001558] is_a: GO:0072078 ! nephron tubule morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0005310 ! pronephric nephron tubule relationship: part_of GO:0039007 ! pronephric nephron morphogenesis relationship: part_of GO:0039020 ! pronephric nephron tubule development relationship: results_in_morphogenesis_of UBERON:0005310 ! pronephric nephron tubule created_by: bf creation_date: 2010-07-02T09:45:55Z [Term] id: GO:0039014 name: cell differentiation involved in pronephros development namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephros as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] synonym: "cell differentiation involved in pronephric kidney development" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0061005 ! cell differentiation involved in kidney development intersection_of: GO:0030154 ! cell differentiation intersection_of: part_of GO:0048793 ! pronephros development relationship: part_of GO:0048793 ! pronephros development created_by: bf creation_date: 2010-07-02T09:59:25Z [Term] id: GO:0039015 name: cell proliferation involved in pronephros development namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of the population in the pronephros." [GOC:mtg_kidney_jan10] synonym: "cell proliferation involved in pronephric kidney development" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0072111 ! cell proliferation involved in kidney development intersection_of: GO:0008283 ! cell population proliferation intersection_of: part_of GO:0048793 ! pronephros development relationship: part_of GO:0048793 ! pronephros development created_by: bf creation_date: 2010-07-02T10:01:49Z [Term] id: GO:0039016 name: cell-cell signaling involved in pronephros development namespace: biological_process def: "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the pronephros over time, from its formation to the mature organ." [GOC:mtg_kidney_jan10] synonym: "cell-cell signaling involved in pronephric kidney development" EXACT [GOC:mtg_kidney_jan10] synonym: "cell-cell signalling involved in pronephros development" EXACT [GOC:mah] is_a: GO:0060995 ! cell-cell signaling involved in kidney development intersection_of: GO:0007267 ! cell-cell signaling intersection_of: part_of GO:0048793 ! pronephros development relationship: part_of GO:0048793 ! pronephros development created_by: bf creation_date: 2010-07-02T10:03:16Z [Term] id: GO:0039017 name: pattern specification involved in pronephros development namespace: biological_process def: "Any developmental process that results in the creation of defined areas or spaces within the pronephros to which cells respond and eventually are instructed to differentiate." [GOC:mtg_kidney_jan10] synonym: "pattern specification involved in pronephric kidney development" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0061004 ! pattern specification involved in kidney development intersection_of: GO:0007389 ! pattern specification process intersection_of: part_of GO:0048793 ! pronephros development relationship: part_of GO:0048793 ! pronephros development created_by: bf creation_date: 2010-07-02T10:04:39Z [Term] id: GO:0039019 name: pronephric nephron development namespace: biological_process def: "The process whose specific outcome is the progression of the pronephric nephron over time, from its formation to the mature structure. A pronephric nephron is the functional unit of the pronephros." [GOC:mtg_kidney_jan10, XAO:00002785] is_a: GO:0072006 ! nephron development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005309 ! pronephric nephron relationship: part_of GO:0048793 ! pronephros development relationship: results_in_development_of UBERON:0005309 ! pronephric nephron created_by: bf creation_date: 2010-07-02T10:10:20Z [Term] id: GO:0039020 name: pronephric nephron tubule development namespace: biological_process def: "The process whose specific outcome is the progression of a pronephric nephron tubule over time, from its formation to the mature structure. The pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron and connects the filtration unit (glomerulus or glomus) of the pronephros to the pronephric duct." [GOC:mtg_kidney_jan10, PMID:19909807, PMID:9268568] is_a: GO:0072080 ! nephron tubule development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005310 ! pronephric nephron tubule relationship: part_of GO:0039019 ! pronephric nephron development relationship: results_in_development_of UBERON:0005310 ! pronephric nephron tubule created_by: bf creation_date: 2010-07-02T10:11:36Z [Term] id: GO:0039022 name: pronephric duct development namespace: biological_process def: "The process whose specific outcome is the progression of the pronephric duct over time, from its formation to the mature structure. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the pronephric kidney." [GOC:mtg_kidney_jan10, PMID:15647339, XAO:0000063, ZFA:0000150] is_a: GO:0072176 ! nephric duct development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003060 ! pronephric duct relationship: part_of GO:0048793 ! pronephros development relationship: results_in_development_of UBERON:0003060 ! pronephric duct created_by: bf creation_date: 2010-07-02T10:15:03Z [Term] id: GO:0039023 name: pronephric duct morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the pronephric duct are generated and organized. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the kidney." [GOC:mtg_kidney_jan10, XAO:0000063, ZFA:0000150] is_a: GO:0072178 ! nephric duct morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003060 ! pronephric duct relationship: part_of GO:0039022 ! pronephric duct development relationship: part_of GO:0072114 ! pronephros morphogenesis relationship: results_in_morphogenesis_of UBERON:0003060 ! pronephric duct created_by: bf creation_date: 2010-07-02T10:18:09Z [Term] id: GO:0040003 name: chitin-based cuticle development namespace: biological_process def: "Synthesis and deposition of a chitin-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this process is found in Drosophila melanogaster." [GOC:mtg_sensu] synonym: "chitin-based cuticle anabolism" EXACT [] synonym: "chitin-based cuticle biosynthetic process" EXACT [] synonym: "chitin-based cuticle formation" EXACT [] synonym: "chitin-based cuticle synthesis" EXACT [] is_a: GO:0042335 ! cuticle development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001001 ! chitin-based cuticle relationship: in_taxon NCBITaxon:6656 {all_only="true"} ! Arthropoda relationship: only_in_taxon NCBITaxon:6656 ! Arthropoda relationship: results_in_development_of UBERON:0001001 ! chitin-based cuticle [Term] id: GO:0040007 name: growth namespace: biological_process alt_id: GO:0048590 def: "The increase in size or mass of an entire organism, a part of an organism or a cell." [GOC:bf, GOC:ma] comment: See also the biological process term 'cell growth ; GO:0016049'. subset: gocheck_do_not_annotate subset: goslim_chembl subset: goslim_pir subset: goslim_plant synonym: "growth pattern" RELATED [] synonym: "non-developmental growth" RELATED [GOC:mah] is_a: GO:0008150 ! biological process relationship: in_taxon NCBITaxon:131567 {all_only="true"} ! cellular organisms relationship: only_in_taxon NCBITaxon:131567 ! cellular organisms [Term] id: GO:0040008 name: regulation of growth namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development." [GOC:ems, GOC:mah] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0040007 ! growth relationship: regulates GO:0040007 ! growth [Term] id: GO:0040011 name: locomotion namespace: biological_process def: "Self-propelled movement of a cell or organism from one location to another." [GOC:dgh] subset: goslim_chembl subset: goslim_pir is_a: GO:0008150 ! biological process property_value: RO:0002161 NCBITaxon:451864 [Term] id: GO:0040012 name: regulation of locomotion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of locomotion of a cell or organism." [GOC:ems] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0040011 ! locomotion relationship: regulates GO:0040011 ! locomotion [Term] id: GO:0040013 name: negative regulation of locomotion namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of locomotion of a cell or organism." [GOC:go_curators] synonym: "down regulation of locomotion" EXACT [] synonym: "down-regulation of locomotion" EXACT [] synonym: "downregulation of locomotion" EXACT [] synonym: "inhibition of locomotion" NARROW [] is_a: GO:0040012 ! regulation of locomotion is_a: GO:0048519 ! negative regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0040011 ! locomotion relationship: negatively_regulates GO:0040011 ! locomotion [Term] id: GO:0040014 name: regulation of multicellular organism growth namespace: biological_process def: "Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size." [GOC:dph, GOC:ems, GOC:tb] synonym: "regulation of body growth" EXACT [GOC:dph, GOC:tb] synonym: "regulation of body size" EXACT [GOC:dph, GOC:tb] is_a: GO:0048638 ! regulation of developmental growth is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0035264 ! multicellular organism growth relationship: regulates GO:0035264 ! multicellular organism growth [Term] id: GO:0040015 name: negative regulation of multicellular organism growth namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organism to reach its usual body size." [GOC:dph, GOC:ems, GOC:tb] synonym: "negative regulation of body growth" EXACT [GOC:dph, GOC:tb] synonym: "negative regulation of body size" EXACT [GOC:dph, GOC:tb] is_a: GO:0040014 ! regulation of multicellular organism growth is_a: GO:0048640 ! negative regulation of developmental growth is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0035264 ! multicellular organism growth relationship: negatively_regulates GO:0035264 ! multicellular organism growth [Term] id: GO:0040016 name: embryonic cleavage namespace: biological_process def: "The first few specialized divisions of an activated animal egg." [GOC:clt, ISBN:0070524300] is_a: GO:0051301 ! cell division relationship: part_of GO:0009790 ! embryo development [Term] id: GO:0040017 name: positive regulation of locomotion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism." [GOC:go_curators] synonym: "activation of locomotion" NARROW [] synonym: "stimulation of locomotion" NARROW [] synonym: "up regulation of locomotion" EXACT [] synonym: "up-regulation of locomotion" EXACT [] synonym: "upregulation of locomotion" EXACT [] is_a: GO:0040012 ! regulation of locomotion is_a: GO:0048518 ! positive regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0040011 ! locomotion relationship: positively_regulates GO:0040011 ! locomotion [Term] id: GO:0040018 name: positive regulation of multicellular organism growth namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "positive regulation of body growth" EXACT [GOC:dph, GOC:tb] synonym: "positive regulation of body size" EXACT [GOC:dph, GOC:tb] is_a: GO:0040014 ! regulation of multicellular organism growth is_a: GO:0048639 ! positive regulation of developmental growth is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0035264 ! multicellular organism growth relationship: positively_regulates GO:0035264 ! multicellular organism growth [Term] id: GO:0040019 name: positive regulation of embryonic development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of embryonic development." [GOC:go_curators] synonym: "activation of embryonic development" NARROW [] synonym: "stimulation of embryonic development" NARROW [] synonym: "up regulation of embryonic development" EXACT [] synonym: "up-regulation of embryonic development" EXACT [] synonym: "upregulation of embryonic development" EXACT [] is_a: GO:0045995 ! regulation of embryonic development is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0009790 ! embryo development relationship: positively_regulates GO:0009790 ! embryo development [Term] id: GO:0040020 name: regulation of meiotic nuclear division namespace: biological_process def: "Any process that modulates the frequency, rate or extent of meiotic nuclear division, the process in which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes." [GOC:ems, GOC:ma] synonym: "regulation of meiosis" BROAD [GOC:vw] is_a: GO:0010564 ! regulation of cell cycle process is_a: GO:0051445 ! regulation of meiotic cell cycle is_a: GO:0051783 ! regulation of nuclear division intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0140013 ! meiotic nuclear division relationship: regulates GO:0140013 ! meiotic nuclear division [Term] id: GO:0040034 name: regulation of development, heterochronic namespace: biological_process def: "Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and the rate at which this time point is reached." [PMID:9442909] synonym: "developmental timing" RELATED [] synonym: "heterochronic regulation of development" EXACT [] synonym: "temporal regulation of development" EXACT [] is_a: GO:0050793 ! regulation of developmental process [Term] id: GO:0042063 name: gliogenesis namespace: biological_process def: "The process that results in the generation of glial cells. This includes the production of glial progenitors and their differentiation into mature glia." [GOC:dgh, GOC:jid] synonym: "glial cell generation" EXACT systematic_synonym [] is_a: GO:0022008 ! neurogenesis intersection_of: GO:0008150 ! biological process intersection_of: results_in_formation_of_anatomical_entity CL:0000125 ! glial cell relationship: results_in_formation_of_anatomical_entity CL:0000125 ! glial cell [Term] id: GO:0042065 name: glial cell growth namespace: biological_process def: "Growth of glial cells, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system." [GOC:dph, GOC:isa_complete, GOC:jid] is_a: GO:0048588 ! developmental cell growth intersection_of: GO:0040007 ! growth intersection_of: results_in_growth_of CL:0000125 ! glial cell relationship: part_of GO:0042063 ! gliogenesis relationship: results_in_growth_of CL:0000125 ! glial cell [Term] id: GO:0042069 name: regulation of catecholamine metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catecholamines." [GOC:go_curators] synonym: "regulation of catecholamine metabolism" EXACT [] is_a: GO:0031323 ! regulation of cellular metabolic process is_a: GO:0033238 ! regulation of amine metabolic process is_a: GO:0080090 ! regulation of primary metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006584 ! catecholamine metabolic process relationship: regulates GO:0006584 ! catecholamine metabolic process [Term] id: GO:0042073 name: intraciliary transport namespace: biological_process alt_id: GO:0035734 def: "The bidirectional movement of large protein complexes along microtubules within a cilium, mediated by motor proteins." [GOC:cilia, GOC:kmv, PMID:17981739, PMID:18180368, PMID:22869374, Reactome:R-HSA-5620924.2] comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. synonym: "IFT" RELATED [] synonym: "intraflagellar transport" EXACT [] synonym: "intraflagellar transport involved in cilium organization" EXACT [] synonym: "intraflagellar transport involved in microtubule-based flagellum organisation" EXACT [] xref: Wikipedia:Intraflagellar_transport is_a: GO:0010970 ! transport along microtubule is_a: GO:0031503 ! protein-containing complex localization intersection_of: GO:0006810 ! transport intersection_of: has_primary_input GO:0032991 ! protein-containing complex intersection_of: occurs_in GO:0005929 ! cilium intersection_of: results_in_transport_along GO:0005874 ! microtubule relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota relationship: occurs_in GO:0005929 ! cilium relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota relationship: part_of GO:0044782 ! cilium organization property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3312 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4890 property_value: RO:0002161 NCBITaxon:5782 [Term] id: GO:0042074 name: cell migration involved in gastrulation namespace: biological_process def: "The migration of individual cells within the blastocyst to help establish the multi-layered body plan of the organism (gastrulation). For example, the migration of cells from the surface to the interior of the embryo (ingression)." [GOC:jl, http://www.cellmigration.org/, ISBN:0878932437] is_a: GO:0001667 ! ameboidal-type cell migration intersection_of: GO:0016477 ! cell migration intersection_of: part_of GO:0007369 ! gastrulation relationship: part_of GO:0007369 ! gastrulation [Term] id: GO:0042078 name: germ-line stem cell division namespace: biological_process alt_id: GO:0048131 def: "The self-renewing division of a germline stem cell to produce a daughter stem cell and a daughter germ cell, which will divide to form the gametes." [GOC:jid, PMID:2279698] synonym: "germ-line stem cell renewal" EXACT [] is_a: GO:0017145 ! stem cell division is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism intersection_of: GO:0051301 ! cell division intersection_of: has_primary_input CL:0000014 ! germ line stem cell relationship: has_primary_input CL:0000014 ! germ line stem cell relationship: part_of GO:0007281 ! germ cell development [Term] id: GO:0042098 name: T cell proliferation namespace: biological_process alt_id: GO:0042111 def: "The expansion of a T cell population by cell division. Follows T cell activation." [GOC:jl] synonym: "T lymphocyte proliferation" EXACT [] synonym: "T-cell proliferation" EXACT [] synonym: "T-lymphocyte proliferation" EXACT [] is_a: GO:0042110 ! T cell activation is_a: GO:0046651 ! lymphocyte proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000084 ! T cell relationship: acts_on_population_of CL:0000084 ! T cell [Term] id: GO:0042102 name: positive regulation of T cell proliferation namespace: biological_process def: "Any process that activates or increases the rate or extent of T cell proliferation." [GOC:ai] synonym: "activation of T cell proliferation" NARROW [] synonym: "positive regulation of T lymphocyte proliferation" EXACT [] synonym: "positive regulation of T-lymphocyte proliferation" EXACT [] synonym: "stimulation of T cell proliferation" NARROW [] synonym: "up regulation of T cell proliferation" EXACT [] synonym: "up-regulation of T cell proliferation" EXACT [] synonym: "upregulation of T cell proliferation" EXACT [] is_a: GO:0042129 ! regulation of T cell proliferation is_a: GO:0050671 ! positive regulation of lymphocyte proliferation is_a: GO:0050870 ! positive regulation of T cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0042098 ! T cell proliferation relationship: positively_regulates GO:0042098 ! T cell proliferation [Term] id: GO:0042103 name: positive regulation of T cell homeostatic proliferation namespace: biological_process def: "Any process that activates or increases the rate or extent of resting T cell proliferation." [GOC:jl] synonym: "activation of T cell homeostatic proliferation" NARROW [] synonym: "positive regulation of resting T cell proliferation" EXACT [] synonym: "positive regulation of T lymphocyte homeostatic proliferation" EXACT [] synonym: "positive regulation of T-cell homeostatic proliferation" EXACT [] synonym: "positive regulation of T-lymphocyte homeostatic proliferation" EXACT [] synonym: "stimulation of T cell homeostatic proliferation" NARROW [] synonym: "up regulation of T cell homeostatic proliferation" EXACT [] synonym: "up-regulation of T cell homeostatic proliferation" EXACT [] synonym: "upregulation of T cell homeostatic proliferation" EXACT [] is_a: GO:0042102 ! positive regulation of T cell proliferation is_a: GO:0046013 ! regulation of T cell homeostatic proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001777 ! T cell homeostatic proliferation relationship: positively_regulates GO:0001777 ! T cell homeostatic proliferation [Term] id: GO:0042110 name: T cell activation namespace: biological_process def: "The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific." [GOC:mgi_curators, ISBN:0781735149] synonym: "T lymphocyte activation" EXACT [] synonym: "T-cell activation" EXACT [] synonym: "T-lymphocyte activation" EXACT [] is_a: GO:0046649 ! lymphocyte activation intersection_of: GO:0001775 ! cell activation intersection_of: has_primary_input CL:0000084 ! T cell relationship: has_primary_input CL:0000084 ! T cell [Term] id: GO:0042118 name: endothelial cell activation namespace: biological_process def: "The change in morphology and behavior of an endothelial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor." [GOC:mgi_curators, ISBN:0781735149, PMID:12851652, PMID:14581484] is_a: GO:0001775 ! cell activation intersection_of: GO:0001775 ! cell activation intersection_of: has_primary_input CL:0000115 ! endothelial cell relationship: has_primary_input CL:0000115 ! endothelial cell [Term] id: GO:0042127 name: regulation of cell population proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell proliferation." [GOC:jl] synonym: "regulation of cell proliferation" RELATED [] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0008283 ! cell population proliferation relationship: regulates GO:0008283 ! cell population proliferation property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0042129 name: regulation of T cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of T cell proliferation." [GOC:jl] synonym: "regulation of T lymphocyte proliferation" EXACT [] synonym: "regulation of T-cell proliferation" EXACT [] synonym: "regulation of T-lymphocyte proliferation" EXACT [] is_a: GO:0050670 ! regulation of lymphocyte proliferation is_a: GO:0050863 ! regulation of T cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0042098 ! T cell proliferation relationship: regulates GO:0042098 ! T cell proliferation [Term] id: GO:0042130 name: negative regulation of T cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of T cell proliferation." [GOC:jl] synonym: "down regulation of T cell proliferation" EXACT [] synonym: "down-regulation of T cell proliferation" EXACT [] synonym: "downregulation of T cell proliferation" EXACT [] synonym: "inhibition of T cell proliferation" NARROW [] synonym: "negative regulation of T lymphocyte proliferation" EXACT [] synonym: "negative regulation of T-cell proliferation" EXACT [] synonym: "negative regulation of T-lymphocyte proliferation" EXACT [] is_a: GO:0042129 ! regulation of T cell proliferation is_a: GO:0050672 ! negative regulation of lymphocyte proliferation is_a: GO:0050868 ! negative regulation of T cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0042098 ! T cell proliferation relationship: negatively_regulates GO:0042098 ! T cell proliferation [Term] id: GO:0042175 name: nuclear outer membrane-endoplasmic reticulum membrane network namespace: cellular_component def: "The continuous network of membranes encompassing the nuclear outer membrane and the endoplasmic reticulum membrane." [GOC:bf, GOC:jl, GOC:mah, GOC:mcc, GOC:pr, GOC:vw] synonym: "NE-ER continuum" RELATED [] synonym: "NE-ER network" RELATED [] synonym: "nuclear envelope-endoplasmic reticulum continuum" RELATED [] synonym: "nuclear envelope-endoplasmic reticulum network" RELATED [GOC:mah] synonym: "nuclear envelope-ER network" RELATED [] synonym: "nuclear membrane-endoplasmic reticulum continuum" EXACT [GOC:mah] synonym: "nuclear membrane-ER network" EXACT [GOC:mah] is_a: GO:0016020 ! membrane relationship: part_of GO:0012505 ! endomembrane system [Term] id: GO:0042176 name: regulation of protein catabolic process namespace: biological_process alt_id: GO:1903362 alt_id: GO:2000598 def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds." [GOC:go_curators, GOC:jl] synonym: "regulation of cellular protein breakdown" EXACT [GOC:TermGenie] synonym: "regulation of cellular protein catabolic process" EXACT [] synonym: "regulation of cellular protein catabolism" EXACT [GOC:TermGenie] synonym: "regulation of cellular protein degradation" EXACT [GOC:TermGenie] synonym: "regulation of cyclin breakdown" NARROW [GOC:obol] synonym: "regulation of cyclin catabolic process" NARROW [] synonym: "regulation of cyclin catabolism" NARROW [GOC:obol] synonym: "regulation of cyclin degradation" NARROW [GOC:obol] synonym: "regulation of degradation of cyclin" NARROW [GOC:obol] synonym: "regulation of protein breakdown" EXACT [] synonym: "regulation of protein catabolism" EXACT [] synonym: "regulation of protein degradation" EXACT [] is_a: GO:0009894 ! regulation of catabolic process is_a: GO:0051246 ! regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030163 ! protein catabolic process relationship: regulates GO:0030163 ! protein catabolic process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23112" xsd:anyURI created_by: kmv creation_date: 2014-08-21T15:05:45Z [Term] id: GO:0042177 name: negative regulation of protein catabolic process namespace: biological_process alt_id: GO:1903363 alt_id: GO:2000599 def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process." [GO_REF:0000058, GOC:kmv, GOC:obol, GOC:TermGenie, PMID:24785082] synonym: "down regulation of cellular protein breakdown" EXACT [GOC:TermGenie] synonym: "down regulation of cellular protein catabolic process" EXACT [GOC:TermGenie] synonym: "down regulation of cellular protein catabolism" EXACT [GOC:TermGenie] synonym: "down regulation of cellular protein degradation" EXACT [GOC:TermGenie] synonym: "down regulation of protein catabolic process" EXACT [] synonym: "down-regulation of cellular protein breakdown" EXACT [GOC:TermGenie] synonym: "down-regulation of cellular protein catabolic process" EXACT [GOC:TermGenie] synonym: "down-regulation of cellular protein catabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of cellular protein degradation" EXACT [GOC:TermGenie] synonym: "down-regulation of protein catabolic process" EXACT [] synonym: "downregulation of cellular protein breakdown" EXACT [GOC:TermGenie] synonym: "downregulation of cellular protein catabolic process" EXACT [GOC:TermGenie] synonym: "downregulation of cellular protein catabolism" EXACT [GOC:TermGenie] synonym: "downregulation of cellular protein degradation" EXACT [GOC:TermGenie] synonym: "downregulation of protein catabolic process" EXACT [] synonym: "inhibition of cellular protein breakdown" NARROW [GOC:TermGenie] synonym: "inhibition of cellular protein catabolic process" NARROW [GOC:TermGenie] synonym: "inhibition of cellular protein catabolism" NARROW [GOC:TermGenie] synonym: "inhibition of cellular protein degradation" NARROW [GOC:TermGenie] synonym: "inhibition of protein catabolic process" NARROW [] synonym: "negative regulation of cellular protein breakdown" EXACT [GOC:TermGenie] synonym: "negative regulation of cellular protein catabolic process" EXACT [] synonym: "negative regulation of cellular protein catabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of cellular protein degradation" EXACT [GOC:TermGenie] synonym: "negative regulation of protein breakdown" EXACT [] synonym: "negative regulation of protein catabolism" EXACT [] synonym: "negative regulation of protein degradation" EXACT [] is_a: GO:0009895 ! negative regulation of catabolic process is_a: GO:0042176 ! regulation of protein catabolic process is_a: GO:0051248 ! negative regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030163 ! protein catabolic process relationship: negatively_regulates GO:0030163 ! protein catabolic process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23112" xsd:anyURI [Term] id: GO:0042180 name: cellular ketone metabolic process namespace: biological_process def: "The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups." [GOC:jl, ISBN:0787650153] subset: goslim_pir synonym: "ketone metabolism" EXACT [] is_a: GO:0044237 ! cellular metabolic process is_a: GO:0044281 ! small molecule metabolic process is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:17087 ! ketone relationship: has_primary_input_or_output CHEBI:17087 ! ketone [Term] id: GO:0042181 name: ketone biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups." [GOC:go_curators] synonym: "ketone anabolism" EXACT [] synonym: "ketone biosynthesis" EXACT [] synonym: "ketone formation" EXACT [] synonym: "ketone synthesis" EXACT [] is_a: GO:0042180 ! cellular ketone metabolic process is_a: GO:0044249 ! cellular biosynthetic process is_a: GO:0044283 ! small molecule biosynthetic process is_a: GO:1901576 ! organic substance biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:17087 ! ketone relationship: has_primary_output CHEBI:17087 ! ketone [Term] id: GO:0042182 name: ketone catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups." [GOC:go_curators] synonym: "ketone breakdown" EXACT [] synonym: "ketone catabolism" EXACT [] synonym: "ketone degradation" EXACT [] is_a: GO:0042180 ! cellular ketone metabolic process is_a: GO:0044248 ! cellular catabolic process is_a: GO:0044282 ! small molecule catabolic process is_a: GO:1901575 ! organic substance catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:17087 ! ketone relationship: has_primary_input CHEBI:17087 ! ketone [Term] id: GO:0042221 name: response to chemical namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus." [GOC:jl] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_manually_annotate subset: goslim_candida subset: goslim_drosophila subset: goslim_metagenomics subset: goslim_plant subset: goslim_yeast synonym: "response to chemical stimulus" EXACT [GOC:dos] synonym: "response to chemical substance" EXACT [] is_a: GO:0050896 ! response to stimulus intersection_of: GO:0050896 ! response to stimulus intersection_of: has_primary_input CHEBI:24431 ! chemical entity relationship: has_primary_input CHEBI:24431 ! chemical entity [Term] id: GO:0042254 name: ribosome biogenesis namespace: biological_process alt_id: GO:0007046 def: "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis." [GOC:ma, PMID:26404467, Wikipedia:Ribosome_biogenesis] subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_pir subset: goslim_pombe subset: goslim_prokaryote synonym: "ribosome biogenesis and assembly" EXACT [] is_a: GO:0022613 ! ribonucleoprotein complex biogenesis [Term] id: GO:0042255 name: ribosome assembly namespace: biological_process alt_id: GO:0042257 def: "The aggregation, arrangement and bonding together of the mature ribosome and of its subunits." [GOC:ma, PMID:30467428] subset: goslim_yeast synonym: "ribosomal subunit assembly" NARROW [GOC:mah, GOC:vw] is_a: GO:0140694 ! non-membrane-bounded organelle assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0005840 ! ribosome relationship: part_of GO:0042254 ! ribosome biogenesis relationship: results_in_assembly_of GO:0005840 ! ribosome [Term] id: GO:0042325 name: regulation of phosphorylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule." [GOC:jl] is_a: GO:0019220 ! regulation of phosphate metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0016310 ! phosphorylation relationship: regulates GO:0016310 ! phosphorylation [Term] id: GO:0042326 name: negative regulation of phosphorylation namespace: biological_process def: "Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule." [GOC:jl] synonym: "down regulation of phosphorylation" EXACT [] synonym: "down-regulation of phosphorylation" EXACT [] synonym: "downregulation of phosphorylation" EXACT [] synonym: "inhibition of phosphorylation" NARROW [] is_a: GO:0042325 ! regulation of phosphorylation is_a: GO:0045936 ! negative regulation of phosphate metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0016310 ! phosphorylation relationship: negatively_regulates GO:0016310 ! phosphorylation [Term] id: GO:0042327 name: positive regulation of phosphorylation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule." [GOC:jl] synonym: "activation of phosphorylation" NARROW [] synonym: "stimulation of phosphorylation" NARROW [] synonym: "up regulation of phosphorylation" EXACT [] synonym: "up-regulation of phosphorylation" EXACT [] synonym: "upregulation of phosphorylation" EXACT [] is_a: GO:0042325 ! regulation of phosphorylation is_a: GO:0045937 ! positive regulation of phosphate metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0016310 ! phosphorylation relationship: positively_regulates GO:0016310 ! phosphorylation [Term] id: GO:0042335 name: cuticle development namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of a cuticle, the outer layer of some animals and plants, which acts to prevent water loss." [ISBN:0192800825] subset: goslim_drosophila synonym: "cuticle anabolism" EXACT [] synonym: "cuticle biosynthesis" EXACT [] synonym: "cuticle biosynthetic process" EXACT [] synonym: "cuticle formation" EXACT [] synonym: "cuticle synthesis" EXACT [] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001002 ! cuticle relationship: part_of GO:0007275 ! multicellular organism development relationship: results_in_development_of UBERON:0001002 ! cuticle [Term] id: GO:0042391 name: regulation of membrane potential namespace: biological_process def: "Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane." [GOC:jl, GOC:mtg_cardio, GOC:tb, ISBN:0198506732] is_a: BFO:0000003 ! occurrent relationship: has_part GO:0034220 ! monoatomic ion transmembrane transport [Term] id: GO:0042401 name: biogenic amine biosynthetic process namespace: biological_process def: "The chemical reactions and pathways occurring at the level of individual cells resulting in the formation of any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters." [GOC:jl, ISBN:0395825172] synonym: "biogenic amine anabolism" EXACT [] synonym: "biogenic amine biosynthesis" EXACT [] synonym: "biogenic amine formation" EXACT [] synonym: "biogenic amine synthesis" EXACT [] synonym: "cellular biogenic amine biosynthetic process" EXACT [] is_a: GO:0006576 ! biogenic amine metabolic process is_a: GO:0009309 ! amine biosynthetic process [Term] id: GO:0042402 name: cellular biogenic amine catabolic process namespace: biological_process def: "The chemical reactions and pathways occurring at the level of individual cells resulting in the breakdown of biogenic amines, any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters." [GOC:go_curators, GOC:jl, ISBN:0198506732] synonym: "biogenic amine breakdown" EXACT [] synonym: "biogenic amine catabolism" EXACT [] synonym: "biogenic amine degradation" EXACT [] is_a: GO:0009310 ! amine catabolic process [Term] id: GO:0042415 name: norepinephrine metabolic process namespace: biological_process def: "The chemical reactions and pathways involving norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine." [GOC:jl, ISBN:0198506732] synonym: "levarterenol metabolic process" EXACT [] synonym: "levarterenol metabolism" EXACT [] synonym: "noradrenaline metabolic process" EXACT [] synonym: "noradrenaline metabolism" EXACT [] synonym: "norepinephrine metabolism" EXACT [] is_a: GO:0006807 ! nitrogen compound metabolic process is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:72587 ! (R)-noradrenaline(1+) relationship: has_primary_input_or_output CHEBI:72587 ! (R)-noradrenaline(1+) [Term] id: GO:0042421 name: norepinephrine biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine." [GOC:jl, ISBN:0198506732] synonym: "levarterenol biosynthesis" EXACT [] synonym: "levarterenol biosynthetic process" EXACT [] synonym: "noradrenaline biosynthesis" EXACT [] synonym: "noradrenaline biosynthetic process" EXACT [] synonym: "norepinephrine anabolism" EXACT [] synonym: "norepinephrine biosynthesis" EXACT [] synonym: "norepinephrine formation" EXACT [] synonym: "norepinephrine synthesis" EXACT [] is_a: GO:0042415 ! norepinephrine metabolic process is_a: GO:1901576 ! organic substance biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:72587 ! (R)-noradrenaline(1+) relationship: has_primary_output CHEBI:72587 ! (R)-noradrenaline(1+) [Term] id: GO:0042422 name: norepinephrine catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine." [GOC:jl, ISBN:0198506732] synonym: "levarterenol catabolic process" EXACT [] synonym: "levarterenol catabolism" EXACT [] synonym: "noradrenaline catabolic process" EXACT [] synonym: "noradrenaline catabolism" EXACT [] synonym: "norepinephrine breakdown" EXACT [] synonym: "norepinephrine catabolism" EXACT [] synonym: "norepinephrine degradation" EXACT [] xref: Wikipedia:Norepinephrine#Degradation is_a: GO:0042415 ! norepinephrine metabolic process is_a: GO:1901575 ! organic substance catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:72587 ! (R)-noradrenaline(1+) relationship: has_primary_input CHEBI:72587 ! (R)-noradrenaline(1+) [Term] id: GO:0042423 name: catecholamine biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." [GOC:jl, ISBN:0198506732] synonym: "catecholamine anabolism" EXACT [] synonym: "catecholamine biosynthesis" EXACT [] synonym: "catecholamine formation" EXACT [] synonym: "catecholamine synthesis" EXACT [] xref: Wikipedia:Catecholamines is_a: GO:0006584 ! catecholamine metabolic process is_a: GO:0009713 ! catechol-containing compound biosynthetic process is_a: GO:0042401 ! biogenic amine biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:33567 ! catecholamine relationship: has_primary_output CHEBI:33567 ! catecholamine [Term] id: GO:0042424 name: catecholamine catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." [GOC:jl, ISBN:0198506732] synonym: "catecholamine breakdown" EXACT [] synonym: "catecholamine catabolism" EXACT [] synonym: "catecholamine degradation" EXACT [] is_a: GO:0006584 ! catecholamine metabolic process is_a: GO:0019614 ! catechol-containing compound catabolic process is_a: GO:0042402 ! cellular biogenic amine catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:33567 ! catecholamine relationship: has_primary_input CHEBI:33567 ! catecholamine [Term] id: GO:0042427 name: serotonin biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties." [GOC:jl, ISBN:0198506732] synonym: "serotonin anabolism" EXACT [] synonym: "serotonin biosynthesis" EXACT [] synonym: "serotonin formation" EXACT [] synonym: "serotonin synthesis" EXACT [] xref: Wikipedia:Serotonin is_a: GO:0009058 ! biosynthetic process is_a: GO:0042428 ! serotonin metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:350546 ! serotonin(1+) relationship: has_primary_output CHEBI:350546 ! serotonin(1+) [Term] id: GO:0042428 name: serotonin metabolic process namespace: biological_process def: "The chemical reactions and pathways involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties." [GOC:jl, ISBN:0198506732] synonym: "serotonin metabolism" EXACT [] is_a: GO:0018958 ! phenol-containing compound metabolic process is_a: GO:0042430 ! indole-containing compound metabolic process is_a: GO:0097164 ! ammonium ion metabolic process is_a: GO:1901160 ! primary amino compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:350546 ! serotonin(1+) relationship: has_primary_input_or_output CHEBI:350546 ! serotonin(1+) [Term] id: GO:0042429 name: serotonin catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties." [GOC:jl, ISBN:0198506732] synonym: "serotonin breakdown" EXACT [] synonym: "serotonin catabolism" EXACT [] synonym: "serotonin degradation" EXACT [] is_a: GO:0009056 ! catabolic process is_a: GO:0042428 ! serotonin metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:350546 ! serotonin(1+) relationship: has_primary_input CHEBI:350546 ! serotonin(1+) [Term] id: GO:0042430 name: indole-containing compound metabolic process namespace: biological_process alt_id: GO:0042434 def: "The chemical reactions and pathways involving compounds that contain an indole (2,3-benzopyrrole) skeleton." [GOC:jl, GOC:mah] synonym: "indole and derivative metabolic process" EXACT [] synonym: "indole and derivative metabolism" EXACT [] synonym: "indole derivative metabolic process" NARROW [] synonym: "indole derivative metabolism" NARROW [] synonym: "indole-containing compound metabolism" EXACT [] synonym: "ketole metabolic process" EXACT [] synonym: "ketole metabolism" EXACT [] is_a: GO:0006725 ! cellular aromatic compound metabolic process is_a: GO:0034641 ! cellular nitrogen compound metabolic process is_a: GO:0046483 ! heterocycle metabolic process is_a: GO:1901360 ! organic cyclic compound metabolic process is_a: GO:1901564 ! organonitrogen compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:24828 ! indoles relationship: has_primary_input_or_output CHEBI:24828 ! indoles [Term] id: GO:0042435 name: indole-containing compound biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of compounds that contain an indole (2,3-benzopyrrole) skeleton." [GOC:jl] synonym: "indole derivative biosynthesis" EXACT [] synonym: "indole derivative biosynthetic process" EXACT [] synonym: "indole-containing compound anabolism" EXACT [] synonym: "indole-containing compound biosynthesis" EXACT [] synonym: "indole-containing compound formation" EXACT [] synonym: "indole-containing compound synthesis" EXACT [] is_a: GO:0018130 ! heterocycle biosynthetic process is_a: GO:0019438 ! aromatic compound biosynthetic process is_a: GO:0042430 ! indole-containing compound metabolic process is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process is_a: GO:1901362 ! organic cyclic compound biosynthetic process is_a: GO:1901566 ! organonitrogen compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:24828 ! indoles relationship: has_primary_output CHEBI:24828 ! indoles [Term] id: GO:0042436 name: indole-containing compound catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of compounds that contain an indole (2,3-benzopyrrole) skeleton." [GOC:jl] synonym: "indole derivative catabolic process" EXACT [] synonym: "indole derivative catabolism" EXACT [] synonym: "indole-containing compound breakdown" EXACT [] synonym: "indole-containing compound catabolism" EXACT [] synonym: "indole-containing compound degradation" EXACT [] is_a: GO:0019439 ! aromatic compound catabolic process is_a: GO:0042430 ! indole-containing compound metabolic process is_a: GO:0044270 ! cellular nitrogen compound catabolic process is_a: GO:0046700 ! heterocycle catabolic process is_a: GO:1901361 ! organic cyclic compound catabolic process is_a: GO:1901565 ! organonitrogen compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:24828 ! indoles relationship: has_primary_input CHEBI:24828 ! indoles [Term] id: GO:0042461 name: photoreceptor cell development namespace: biological_process alt_id: GO:0046531 def: "Development of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light." [GOC:go_curators] synonym: "photoreceptor morphogenesis" EXACT [] is_a: GO:0048666 ! neuron development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000210 ! photoreceptor cell relationship: part_of GO:0046530 ! photoreceptor cell differentiation relationship: results_in_development_of CL:0000210 ! photoreceptor cell [Term] id: GO:0042462 name: eye photoreceptor cell development namespace: biological_process def: "Development of a photoreceptor, a sensory cell in the eye that reacts to the presence of light. They usually contain a pigment that undergoes a chemical change when light is absorbed, thus stimulating a nerve." [GOC:jl, ISBN:0192800981] is_a: GO:0042461 ! photoreceptor cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000287 ! eye photoreceptor cell relationship: part_of GO:0001754 ! eye photoreceptor cell differentiation relationship: results_in_development_of CL:0000287 ! eye photoreceptor cell [Term] id: GO:0042478 name: regulation of eye photoreceptor cell development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of eye photoreceptor development." [GOC:jl] synonym: "regulation of eye photoreceptor development" EXACT [] is_a: GO:0046532 ! regulation of photoreceptor cell differentiation is_a: GO:0060284 ! regulation of cell development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0042462 ! eye photoreceptor cell development relationship: regulates GO:0042462 ! eye photoreceptor cell development [Term] id: GO:0042479 name: positive regulation of eye photoreceptor cell development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of eye photoreceptor development." [GOC:jl] synonym: "activation of eye photoreceptor cell development" NARROW [] synonym: "positive regulation of eye photoreceptor development" EXACT [] synonym: "stimulation of eye photoreceptor cell development" NARROW [] synonym: "up regulation of eye photoreceptor cell development" EXACT [] synonym: "up-regulation of eye photoreceptor cell development" EXACT [] synonym: "upregulation of eye photoreceptor cell development" EXACT [] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0042478 ! regulation of eye photoreceptor cell development is_a: GO:0046534 ! positive regulation of photoreceptor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0042462 ! eye photoreceptor cell development relationship: positively_regulates GO:0042462 ! eye photoreceptor cell development [Term] id: GO:0042480 name: negative regulation of eye photoreceptor cell development namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of eye photoreceptor development." [GOC:jl] synonym: "down regulation of eye photoreceptor cell development" EXACT [] synonym: "down-regulation of eye photoreceptor cell development" EXACT [] synonym: "downregulation of eye photoreceptor cell development" EXACT [] synonym: "inhibition of eye photoreceptor cell development" NARROW [] synonym: "negative regulation of eye photoreceptor development" EXACT [] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0042478 ! regulation of eye photoreceptor cell development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0042462 ! eye photoreceptor cell development relationship: negatively_regulates GO:0042462 ! eye photoreceptor cell development [Term] id: GO:0042551 name: neuron maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for a neuron to attain its fully functional state." [GOC:dph, GOC:jl] is_a: GO:0048469 ! cell maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of CL:0000540 ! neuron relationship: part_of GO:0048666 ! neuron development relationship: results_in_maturation_of CL:0000540 ! neuron [Term] id: GO:0042588 name: zymogen granule namespace: cellular_component def: "A membrane-bounded, cytoplasmic secretory granule found in enzyme-secreting cells and visible by light microscopy. Contain zymogen, an inactive enzyme precursor, often of a digestive enzyme." [GOC:jl, ISBN:0198506732] is_a: GO:0030141 ! secretory granule [Term] id: GO:0042589 name: zymogen granule membrane namespace: cellular_component def: "The lipid bilayer surrounding a zymogen granule." [GOC:jl] is_a: GO:0030667 ! secretory granule membrane intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0042588 ! zymogen granule relationship: bounding_layer_of GO:0042588 ! zymogen granule relationship: part_of GO:0042588 ! zymogen granule [Term] id: GO:0042592 name: homeostatic process namespace: biological_process alt_id: GO:0032844 alt_id: GO:0032845 alt_id: GO:0032846 def: "Any biological process involved in the maintenance of an internal steady state." [GOC:jl, ISBN:0395825172] subset: goslim_agr subset: goslim_chembl subset: goslim_mouse synonym: "activation of homeostatic process" NARROW [] synonym: "homeostasis" EXACT [] synonym: "inhibition of homeostatic process" NARROW [] synonym: "negative regulation of homeostatic process" RELATED [] synonym: "positive regulation of homeostatic process" RELATED [] synonym: "regulation of homeostatic process" RELATED [] is_a: GO:0008150 ! biological process [Term] id: GO:0042611 name: MHC protein complex namespace: cellular_component def: "A transmembrane protein complex composed of an MHC alpha chain and, in most cases, either an MHC class II beta chain or an invariant beta2-microglobin chain, and with or without a bound peptide, lipid, or polysaccharide antigen." [GOC:add, GOC:jl, ISBN:0781735149, PMID:15928678, PMID:16153240] subset: goslim_pir is_a: GO:0098797 ! plasma membrane protein complex [Term] id: GO:0042613 name: MHC class II protein complex namespace: cellular_component def: "A transmembrane protein complex composed of an MHC class II alpha and MHC class II beta chain, and with or without a bound peptide or polysaccharide antigen." [GOC:add, GOC:jl, ISBN:0120781859, PMID:15928678] is_a: GO:0042611 ! MHC protein complex [Term] id: GO:0042641 name: actomyosin namespace: cellular_component def: "Any complex of actin, myosin, and accessory proteins." [GOC:go_curators] synonym: "actomyosin complex" EXACT [] synonym: "actomyosin structure" EXACT [] is_a: GO:0110165 ! cellular anatomical entity relationship: part_of GO:0015629 ! actin cytoskeleton [Term] id: GO:0042670 name: retinal cone cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized features of a retinal cone cell." [GOC:go_curators] is_a: GO:0060219 ! camera-type eye photoreceptor cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000573 ! retinal cone cell relationship: results_in_acquisition_of_features_of CL:0000573 ! retinal cone cell [Term] id: GO:0042692 name: muscle cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a muscle cell." [CL:0000187, GOC:go_curators] synonym: "myogenesis" RELATED [] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000187 ! muscle cell relationship: part_of GO:0061061 ! muscle structure development relationship: results_in_acquisition_of_features_of CL:0000187 ! muscle cell [Term] id: GO:0042698 name: ovulation cycle namespace: biological_process def: "The type of sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years." [ISBN:0721662544] is_a: GO:0048511 ! rhythmic process is_a: GO:0048609 ! multicellular organismal reproductive process relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota [Term] id: GO:0042702 name: uterine wall growth namespace: biological_process def: "The regrowth of the endometrium and blood vessels in the uterus following menstruation, resulting from a rise in progesterone levels." [GOC:jl] is_a: GO:0022602 ! ovulation cycle process is_a: GO:0048589 ! developmental growth intersection_of: GO:0040007 ! growth intersection_of: results_in_growth_of UBERON:0000459 ! uterine wall relationship: part_of GO:0001553 ! luteinization relationship: results_in_growth_of UBERON:0000459 ! uterine wall [Term] id: GO:0042713 name: sperm ejaculation namespace: biological_process def: "The expulsion of seminal fluid, thick white fluid containing spermatozoa, from the male genital tract." [GOC:jl, http://www.cogsci.princeton.edu/~wn/] is_a: GO:0048609 ! multicellular organismal reproductive process relationship: part_of GO:0007320 ! insemination [Term] id: GO:0042742 name: defense response to bacterium namespace: biological_process alt_id: GO:0009816 alt_id: GO:0042830 def: "Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism." [GOC:jl] synonym: "antibacterial peptide activity" RELATED [] synonym: "defence response to bacteria" EXACT [] synonym: "defence response to bacterium" EXACT [] synonym: "defense response to bacteria" EXACT [] synonym: "defense response to bacterium, incompatible interaction" NARROW [] synonym: "resistance response to pathogenic bacteria" NARROW [] synonym: "resistance response to pathogenic bacterium" NARROW [] is_a: GO:0009617 ! response to bacterium is_a: GO:0098542 ! defense response to other organism intersection_of: GO:0006952 ! defense response intersection_of: has_primary_input NCBITaxon:2 ! Bacteria [Term] id: GO:0042762 name: regulation of sulfur metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur, the nonmetallic element sulfur or compounds that contain sulfur." [GOC:go_curators] synonym: "regulation of sulfur metabolism" EXACT [] synonym: "regulation of sulphur metabolic process" EXACT [] synonym: "regulation of sulphur metabolism" EXACT [] is_a: GO:0031323 ! regulation of cellular metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006790 ! sulfur compound metabolic process relationship: regulates GO:0006790 ! sulfur compound metabolic process [Term] id: GO:0042886 name: amide transport namespace: biological_process def: "The directed movement of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl, ISBN:0198506732] subset: goslim_pir is_a: GO:0071705 ! nitrogen compound transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:32988 ! amide relationship: has_primary_input CHEBI:32988 ! amide [Term] id: GO:0042887 name: amide transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, from one side of a membrane to the other." [GOC:jl, ISBN:0198506732] synonym: "amine/amide/polyamine channel activity" NARROW [] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:32988 ! amide relationship: has_primary_input CHEBI:32988 ! amide relationship: part_of GO:0042886 ! amide transport [Term] id: GO:0042981 name: regulation of apoptotic process namespace: biological_process def: "Any process that modulates the occurrence or rate of cell death by apoptotic process." [GOC:jl, GOC:mtg_apoptosis] comment: This term should only be used when it is not possible to determine which phase or subtype of the apoptotic process is regulated by a gene product. Whenever detailed information is available, the more granular children terms should be used. synonym: "apoptosis regulator activity" RELATED [] synonym: "regulation of apoptosis" NARROW [] is_a: GO:0043067 ! regulation of programmed cell death intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006915 ! apoptotic process relationship: regulates GO:0006915 ! apoptotic process [Term] id: GO:0042995 name: cell projection namespace: cellular_component def: "A prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, http://www.cogsci.princeton.edu/~wn/] subset: goslim_agr subset: goslim_flybase_ribbon subset: goslim_mouse subset: goslim_pir subset: goslim_prokaryote synonym: "cell process" BROAD [] synonym: "cellular process" BROAD [] synonym: "cellular projection" EXACT [] is_a: GO:0110165 ! cellular anatomical entity relationship: part_of CL:0000000 ! cell [Term] id: GO:0042996 name: regulation of Golgi to plasma membrane protein transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane." [GOC:jl] is_a: GO:0051223 ! regulation of protein transport is_a: GO:0060627 ! regulation of vesicle-mediated transport is_a: GO:1903076 ! regulation of protein localization to plasma membrane intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0043001 ! Golgi to plasma membrane protein transport relationship: regulates GO:0043001 ! Golgi to plasma membrane protein transport [Term] id: GO:0042997 name: negative regulation of Golgi to plasma membrane protein transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane." [GOC:jl] synonym: "down regulation of Golgi to plasma membrane protein transport" EXACT [] synonym: "down-regulation of Golgi to plasma membrane protein transport" EXACT [] synonym: "downregulation of Golgi to plasma membrane protein transport" EXACT [] synonym: "inhibition of Golgi to plasma membrane protein transport" NARROW [] is_a: GO:0042996 ! regulation of Golgi to plasma membrane protein transport is_a: GO:0051224 ! negative regulation of protein transport is_a: GO:1903077 ! negative regulation of protein localization to plasma membrane intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0043001 ! Golgi to plasma membrane protein transport relationship: negatively_regulates GO:0043001 ! Golgi to plasma membrane protein transport [Term] id: GO:0042998 name: positive regulation of Golgi to plasma membrane protein transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane." [GOC:jl] synonym: "activation of Golgi to plasma membrane protein transport" NARROW [] synonym: "stimulation of Golgi to plasma membrane protein transport" NARROW [] synonym: "up regulation of Golgi to plasma membrane protein transport" EXACT [] synonym: "up-regulation of Golgi to plasma membrane protein transport" EXACT [] synonym: "upregulation of Golgi to plasma membrane protein transport" EXACT [] is_a: GO:0042996 ! regulation of Golgi to plasma membrane protein transport is_a: GO:0051222 ! positive regulation of protein transport is_a: GO:1903078 ! positive regulation of protein localization to plasma membrane intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0043001 ! Golgi to plasma membrane protein transport relationship: positively_regulates GO:0043001 ! Golgi to plasma membrane protein transport [Term] id: GO:0043001 name: Golgi to plasma membrane protein transport namespace: biological_process def: "The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane." [ISBN:0716731363] is_a: GO:0006893 ! Golgi to plasma membrane transport is_a: GO:0015031 ! protein transport is_a: GO:0061951 ! establishment of protein localization to plasma membrane is_a: GO:0072659 ! protein localization to plasma membrane intersection_of: GO:0015031 ! protein transport intersection_of: has_target_end_location GO:0005886 ! plasma membrane intersection_of: has_target_start_location GO:0005794 ! Golgi apparatus intersection_of: process_has_causal_agent GO:0031982 ! vesicle [Term] id: GO:0043005 name: neuron projection namespace: cellular_component def: "A prolongation or process extending from a nerve cell, e.g. an axon or dendrite." [GOC:jl, http://www.cogsci.princeton.edu/~wn/] subset: goslim_pir synonym: "nerve fiber" RELATED [GOC:dph] synonym: "neurite" NARROW [] synonym: "neuron process" EXACT [] synonym: "neuron protrusion" EXACT [NIF_Subcellular:sao250931889] synonym: "neuronal cell projection" EXACT [] xref: NIF_Subcellular:sao867568886 is_a: GO:0120025 ! plasma membrane bounded cell projection intersection_of: GO:0120025 ! plasma membrane bounded cell projection intersection_of: part_of CL:0000540 ! neuron relationship: part_of CL:0000540 ! neuron property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0043009 name: chordate embryonic development namespace: biological_process def: "The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching." [GOC:mtg_sensu] is_a: GO:0009792 ! embryo development ending in birth or egg hatching relationship: in_taxon NCBITaxon:7711 {all_only="true"} ! Chordata relationship: only_in_taxon NCBITaxon:7711 ! Chordata [Term] id: GO:0043010 name: camera-type eye development namespace: biological_process alt_id: GO:0001747 alt_id: GO:0031075 def: "The process whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field." [GOC:go_curators, GOC:mtg_sensu] is_a: GO:0001654 ! eye development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000019 ! camera-type eye relationship: results_in_development_of UBERON:0000019 ! camera-type eye property_value: RO:0002161 NCBITaxon:6656 [Term] id: GO:0043025 name: neuronal cell body namespace: cellular_component def: "The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites." [GOC:go_curators] comment: Note that 'cell body' and 'cell soma' are not used in the literature for cells that lack projections, nor for some cells (e.g. yeast with mating projections) that do have projections. subset: goslim_pir synonym: "neuron cell body" EXACT [] synonym: "neuronal cell soma" EXACT [] xref: NIF_Subcellular:sao1044911821 xref: Wikipedia:Soma_(biology) is_a: GO:0044297 ! cell body intersection_of: GO:0044297 ! cell body intersection_of: part_of CL:0000540 ! neuron relationship: part_of GO:0036477 ! somatodendritic compartment [Term] id: GO:0043029 name: T cell homeostasis namespace: biological_process def: "The process of regulating the proliferation and elimination of T cells such that the total number of T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus." [GOC:mgi_curators, ISBN:0781735149] comment: Note that this term represents the return of T cell levels to stable numbers following an immune response as well as the proliferation and elimination of T cells required to maintain stable numbers in the absence of an outside stimulus. synonym: "T lymphocyte homeostasis" EXACT [] synonym: "T-cell homeostasis" EXACT [] synonym: "T-lymphocyte homeostasis" EXACT [] is_a: GO:0002260 ! lymphocyte homeostasis intersection_of: GO:0048872 ! homeostasis of number of cells intersection_of: acts_on_population_of CL:0000084 ! T cell relationship: acts_on_population_of CL:0000084 ! T cell [Term] id: GO:0043043 name: peptide biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. This may include the translation of a precursor protein and its subsequent processing into a functional peptide." [GOC:dph, GOC:jl] synonym: "peptide anabolism" EXACT [] synonym: "peptide biosynthesis" EXACT [] synonym: "peptide formation" EXACT [] synonym: "peptide synthesis" EXACT [] is_a: GO:0006518 ! peptide metabolic process is_a: GO:0043604 ! amide biosynthetic process is_a: GO:1901566 ! organonitrogen compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:16670 ! peptide relationship: has_primary_output CHEBI:16670 ! peptide [Term] id: GO:0043062 name: extracellular structure organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures in the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane, and also covers the host cell environment outside an intracellular parasite." [GOC:ai, GOC:dph, GOC:jl, GOC:mah] subset: goslim_pir subset: goslim_prokaryote synonym: "extracellular structure organisation" EXACT [] synonym: "extracellular structure organization and biogenesis" EXACT [GOC:dph, GOC:jl, GOC:mah] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0005576 ! extracellular region relationship: results_in_organization_of GO:0005576 ! extracellular region [Term] id: GO:0043065 name: positive regulation of apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process." [GOC:jl, GOC:mtg_apoptosis] comment: This term should only be used when it is not possible to determine which phase or subtype of the apoptotic process is positively regulated by a gene product. Whenever detailed information is available, the more granular children terms should be used. subset: goslim_chembl synonym: "activation of apoptosis" NARROW [] synonym: "positive regulation of apoptosis" NARROW [] synonym: "pro-apoptosis" RELATED [] synonym: "stimulation of apoptosis" NARROW [] synonym: "up regulation of apoptosis" EXACT [] synonym: "up-regulation of apoptosis" EXACT [] synonym: "upregulation of apoptosis" EXACT [] is_a: GO:0042981 ! regulation of apoptotic process is_a: GO:0043068 ! positive regulation of programmed cell death intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006915 ! apoptotic process relationship: positively_regulates GO:0006915 ! apoptotic process [Term] id: GO:0043066 name: negative regulation of apoptotic process namespace: biological_process alt_id: GO:0006916 def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process." [GOC:jl, GOC:mtg_apoptosis] comment: This term should only be used when it is not possible to determine which phase or subtype of the apoptotic process is negatively regulated by a gene product. Whenever detailed information is available, the more granular children terms should be used. synonym: "anti-apoptosis" EXACT [] synonym: "apoptosis inhibitor activity" RELATED [] synonym: "down regulation of apoptosis" EXACT [] synonym: "down-regulation of apoptosis" EXACT [] synonym: "downregulation of apoptosis" EXACT [] synonym: "inhibition of apoptosis" NARROW [] synonym: "negative regulation of apoptosis" NARROW [] synonym: "pro-survival" RELATED [] is_a: GO:0042981 ! regulation of apoptotic process is_a: GO:0043069 ! negative regulation of programmed cell death intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006915 ! apoptotic process relationship: negatively_regulates GO:0006915 ! apoptotic process [Term] id: GO:0043067 name: regulation of programmed cell death namespace: biological_process alt_id: GO:0043070 def: "Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes." [GOC:jl] synonym: "regulation of non-apoptotic programmed cell death" NARROW [] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0012501 ! programmed cell death relationship: regulates GO:0012501 ! programmed cell death [Term] id: GO:0043068 name: positive regulation of programmed cell death namespace: biological_process alt_id: GO:0043071 def: "Any process that activates or increases the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes." [GOC:jl] synonym: "activation of programmed cell death" NARROW [] synonym: "positive regulation of non-apoptotic programmed cell death" NARROW [] synonym: "stimulation of programmed cell death" NARROW [] synonym: "up regulation of programmed cell death" EXACT [] synonym: "up-regulation of programmed cell death" EXACT [] synonym: "upregulation of programmed cell death" EXACT [] is_a: GO:0043067 ! regulation of programmed cell death is_a: GO:0048522 ! positive regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0012501 ! programmed cell death relationship: positively_regulates GO:0012501 ! programmed cell death [Term] id: GO:0043069 name: negative regulation of programmed cell death namespace: biological_process alt_id: GO:0043072 def: "Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes." [GOC:jl] synonym: "down regulation of programmed cell death" EXACT [] synonym: "down-regulation of programmed cell death" EXACT [] synonym: "downregulation of programmed cell death" EXACT [] synonym: "inhibition of programmed cell death" NARROW [] synonym: "negative regulation of non-apoptotic programmed cell death" NARROW [] is_a: GO:0043067 ! regulation of programmed cell death is_a: GO:0048523 ! negative regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0012501 ! programmed cell death relationship: negatively_regulates GO:0012501 ! programmed cell death [Term] id: GO:0043073 name: germ cell nucleus namespace: cellular_component def: "The nucleus of a germ cell, a reproductive cell in multicellular organisms." [CL:0000586, GOC:go_curators] synonym: "germ-cell nucleus" EXACT [] is_a: GO:0005634 ! nucleus intersection_of: GO:0005634 ! nucleus intersection_of: part_of CL:0000586 ! germ cell relationship: part_of CL:0000586 ! germ cell [Term] id: GO:0043085 name: positive regulation of catalytic activity namespace: biological_process alt_id: GO:0048554 def: "Any process that activates or increases the activity of an enzyme." [GOC:ebc, GOC:jl, GOC:tb, GOC:vw] subset: gocheck_do_not_annotate subset: goslim_chembl synonym: "activation of enzyme activity" NARROW [] synonym: "activation of metalloenzyme activity" NARROW [] synonym: "positive regulation of enzyme activity" EXACT [GOC:tb] synonym: "positive regulation of metalloenzyme activity" NARROW [] synonym: "stimulation of enzyme activity" NARROW [] synonym: "stimulation of metalloenzyme activity" NARROW [] synonym: "up regulation of enzyme activity" EXACT [] synonym: "up regulation of metalloenzyme activity" NARROW [] synonym: "up-regulation of enzyme activity" EXACT [] synonym: "up-regulation of metalloenzyme activity" NARROW [] synonym: "upregulation of enzyme activity" EXACT [] synonym: "upregulation of metalloenzyme activity" NARROW [] is_a: GO:0044093 ! positive regulation of molecular function is_a: GO:0050790 ! regulation of catalytic activity intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0003824 ! catalytic activity relationship: positively_regulates GO:0003824 ! catalytic activity [Term] id: GO:0043086 name: negative regulation of catalytic activity namespace: biological_process alt_id: GO:0048553 def: "Any process that stops or reduces the activity of an enzyme." [GOC:ebc, GOC:jl, GOC:tb, GOC:vw] subset: gocheck_do_not_annotate synonym: "down regulation of enzyme activity" EXACT [] synonym: "down regulation of metalloenzyme activity" NARROW [] synonym: "down-regulation of enzyme activity" EXACT [] synonym: "down-regulation of metalloenzyme activity" EXACT [] synonym: "downregulation of enzyme activity" EXACT [] synonym: "downregulation of metalloenzyme activity" NARROW [] synonym: "inhibition of enzyme activity" NARROW [] synonym: "inhibition of metalloenzyme activity" NARROW [] synonym: "negative regulation of enzyme activity" EXACT [GOC:tb] synonym: "negative regulation of metalloenzyme activity" NARROW [] is_a: GO:0044092 ! negative regulation of molecular function is_a: GO:0050790 ! regulation of catalytic activity intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0003824 ! catalytic activity relationship: negatively_regulates GO:0003824 ! catalytic activity [Term] id: GO:0043133 name: hindgut contraction namespace: biological_process def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the hindgut. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The hindgut is the posterior part of the alimentary canal, including the rectum, and the large intestine." [GOC:jl, GOC:mtg_muscle, UBERON:0001046] is_a: GO:0006939 ! smooth muscle contraction is_a: GO:0022600 ! digestive system process intersection_of: GO:0006939 ! smooth muscle contraction intersection_of: occurs_in UBERON:0001046 ! hindgut relationship: occurs_in UBERON:0001046 ! hindgut [Term] id: GO:0043134 name: regulation of hindgut contraction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine." [GOC:jl, UBERON:0001046] is_a: GO:0006940 ! regulation of smooth muscle contraction is_a: GO:0044058 ! regulation of digestive system process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0043133 ! hindgut contraction relationship: regulates GO:0043133 ! hindgut contraction [Term] id: GO:0043143 name: regulation of translation by machinery localization namespace: biological_process def: "Any process in which proteins and protein complexes involved in translation are transported to, or maintained in, a specific location." [GOC:jl] synonym: "establishment and maintenance of translational machinery localization" EXACT [] synonym: "establishment and maintenance of translational protein localization" EXACT [] synonym: "regulation of translation by machinery localisation" EXACT [GOC:mah] synonym: "translational machinery localization" EXACT [GOC:dph, GOC:tb] synonym: "translational protein localization" EXACT [] is_a: GO:0006417 ! regulation of translation is_a: GO:0008104 ! protein localization intersection_of: GO:0008104 ! protein localization intersection_of: part_of GO:0006412 ! translation relationship: part_of GO:0006412 ! translation [Term] id: GO:0043170 name: macromolecule metabolic process namespace: biological_process alt_id: GO:0034960 alt_id: GO:0043283 alt_id: GO:0044259 def: "The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:mah] subset: gocheck_do_not_annotate subset: goslim_pir synonym: "biopolymer metabolic process" EXACT [GOC:mtg_chebi_dec09] synonym: "macromolecule metabolism" EXACT [] synonym: "multicellular organismal macromolecule metabolic process" NARROW [] synonym: "organismal macromolecule metabolism" EXACT [] is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:33694 ! biomacromolecule relationship: has_primary_input_or_output CHEBI:33694 ! biomacromolecule property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI [Term] id: GO:0043171 name: peptide catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another." [GOC:jl] synonym: "peptide breakdown" EXACT [] synonym: "peptide catabolism" EXACT [] synonym: "peptide degradation" EXACT [] is_a: GO:0006518 ! peptide metabolic process is_a: GO:0044248 ! cellular catabolic process is_a: GO:1901565 ! organonitrogen compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:16670 ! peptide relationship: has_primary_input CHEBI:16670 ! peptide [Term] id: GO:0043200 name: response to amino acid namespace: biological_process alt_id: GO:0010237 def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups." [GOC:ef, GOC:mlg] synonym: "response to amino acid stimulus" EXACT [GOC:dos] is_a: GO:0001101 ! response to acid chemical is_a: GO:0010243 ! response to organonitrogen compound is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus intersection_of: has_primary_input CHEBI:33709 ! amino acid relationship: has_primary_input CHEBI:33709 ! amino acid [Term] id: GO:0043207 name: response to external biotic stimulus namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things." [GOC:go_curators] is_a: GO:0009605 ! response to external stimulus is_a: GO:0009607 ! response to biotic stimulus [Term] id: GO:0043226 name: organelle namespace: cellular_component def: "Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane." [GOC:go_curators] subset: goslim_chembl subset: goslim_generic subset: goslim_pir subset: goslim_prokaryote xref: NIF_Subcellular:sao1539965131 xref: Wikipedia:Organelle is_a: GO:0110165 ! cellular anatomical entity [Term] id: GO:0043227 name: membrane-bounded organelle namespace: cellular_component def: "Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane." [GOC:go_curators] synonym: "membrane-enclosed organelle" EXACT [] xref: NIF_Subcellular:sao414196390 is_a: GO:0043226 ! organelle intersection_of: GO:0043226 ! organelle intersection_of: has_part GO:0016020 ! membrane disjoint_from: GO:0043228 ! non-membrane-bounded organelle relationship: has_part GO:0016020 ! membrane [Term] id: GO:0043228 name: non-membrane-bounded organelle namespace: cellular_component def: "Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes." [GOC:go_curators] subset: goslim_mouse synonym: "biological condensate" RELATED [] synonym: "non-membrane-enclosed organelle" EXACT [] xref: NIF_Subcellular:sao1456184038 is_a: GO:0043226 ! organelle property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/21881" xsd:anyURI [Term] id: GO:0043229 name: intracellular organelle namespace: cellular_component def: "Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane." [GOC:go_curators] subset: goslim_pir is_a: GO:0043226 ! organelle intersection_of: GO:0043226 ! organelle intersection_of: part_of GO:0005622 ! intracellular anatomical structure disjoint_from: GO:0043230 ! extracellular organelle relationship: part_of GO:0005622 ! intracellular anatomical structure [Term] id: GO:0043230 name: extracellular organelle namespace: cellular_component def: "Organized structure of distinctive morphology and function, occurring outside the cell. Includes, for example, extracellular membrane vesicles (EMVs) and the cellulosomes of anaerobic bacteria and fungi." [GOC:jl, PMID:9914479] subset: goslim_pir is_a: GO:0043226 ! organelle intersection_of: GO:0043226 ! organelle intersection_of: part_of GO:0005576 ! extracellular region relationship: part_of GO:0005576 ! extracellular region [Term] id: GO:0043231 name: intracellular membrane-bounded organelle namespace: cellular_component def: "Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane." [GOC:go_curators] subset: goslim_pir synonym: "intracellular membrane-enclosed organelle" EXACT [] is_a: GO:0043227 ! membrane-bounded organelle is_a: GO:0043229 ! intracellular organelle intersection_of: GO:0043227 ! membrane-bounded organelle intersection_of: part_of GO:0005622 ! intracellular anatomical structure [Term] id: GO:0043232 name: intracellular non-membrane-bounded organelle namespace: cellular_component def: "Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes." [GOC:go_curators] subset: goslim_pir synonym: "intracellular non-membrane-enclosed organelle" EXACT [] is_a: GO:0043228 ! non-membrane-bounded organelle is_a: GO:0043229 ! intracellular organelle intersection_of: GO:0043228 ! non-membrane-bounded organelle intersection_of: part_of GO:0005622 ! intracellular anatomical structure [Term] id: GO:0043233 name: organelle lumen namespace: cellular_component def: "The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen." [GOC:jl, GOC:mah] subset: goslim_mouse is_a: GO:0031974 ! membrane-enclosed lumen intersection_of: GO:0031974 ! membrane-enclosed lumen intersection_of: part_of GO:0043226 ! organelle relationship: part_of GO:0043226 ! organelle [Term] id: GO:0043242 name: negative regulation of protein-containing complex disassembly namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components." [GOC:jl] synonym: "down regulation of protein complex disassembly" EXACT [] synonym: "down-regulation of protein complex disassembly" EXACT [] synonym: "downregulation of protein complex disassembly" EXACT [] synonym: "inhibition of protein complex disassembly" NARROW [] synonym: "negative regulation of protein complex disassembly" RELATED [] is_a: GO:0043244 ! regulation of protein-containing complex disassembly is_a: GO:0051129 ! negative regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0032984 ! protein-containing complex disassembly relationship: negatively_regulates GO:0032984 ! protein-containing complex disassembly [Term] id: GO:0043243 name: positive regulation of protein-containing complex disassembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components." [GOC:jl] synonym: "activation of protein complex disassembly" NARROW [] synonym: "positive regulation of protein complex disassembly" RELATED [] synonym: "stimulation of protein complex disassembly" NARROW [] synonym: "up regulation of protein complex disassembly" EXACT [] synonym: "up-regulation of protein complex disassembly" EXACT [] synonym: "upregulation of protein complex disassembly" EXACT [] is_a: GO:0043244 ! regulation of protein-containing complex disassembly is_a: GO:0051130 ! positive regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0032984 ! protein-containing complex disassembly relationship: positively_regulates GO:0032984 ! protein-containing complex disassembly [Term] id: GO:0043244 name: regulation of protein-containing complex disassembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components." [GOC:jl] synonym: "regulation of protein complex disassembly" RELATED [] is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0032984 ! protein-containing complex disassembly relationship: regulates GO:0032984 ! protein-containing complex disassembly [Term] id: GO:0043249 name: erythrocyte maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for an erythrocyte to attain its fully functional state." [GOC:devbiol, GOC:jl] synonym: "RBC maturation" EXACT [CL:0000232] synonym: "red blood cell maturation" EXACT [CL:0000232] is_a: GO:0048469 ! cell maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of CL:0000232 ! erythrocyte relationship: part_of GO:0048821 ! erythrocyte development relationship: results_in_maturation_of CL:0000232 ! erythrocyte [Term] id: GO:0043254 name: regulation of protein-containing complex assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein complex assembly." [GOC:jl] synonym: "regulation of protein complex assembly" RELATED [] is_a: GO:0044087 ! regulation of cellular component biogenesis is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0065003 ! protein-containing complex assembly relationship: regulates GO:0065003 ! protein-containing complex assembly [Term] id: GO:0043255 name: regulation of carbohydrate biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of carbohydrates." [GOC:jl] synonym: "regulation of carbohydrate anabolism" EXACT [] synonym: "regulation of carbohydrate biosynthesis" EXACT [] synonym: "regulation of carbohydrate formation" EXACT [] synonym: "regulation of carbohydrate synthesis" EXACT [] is_a: GO:0006109 ! regulation of carbohydrate metabolic process is_a: GO:0009889 ! regulation of biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0016051 ! carbohydrate biosynthetic process relationship: regulates GO:0016051 ! carbohydrate biosynthetic process [Term] id: GO:0043264 name: extracellular non-membrane-bounded organelle namespace: cellular_component def: "Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring outside the cell." [GOC:jl] synonym: "extracellular non-membrane-enclosed organelle" EXACT [] is_a: GO:0043228 ! non-membrane-bounded organelle is_a: GO:0043230 ! extracellular organelle intersection_of: GO:0043228 ! non-membrane-bounded organelle intersection_of: part_of GO:0005576 ! extracellular region [Term] id: GO:0043269 name: regulation of monoatomic ion transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl] synonym: "regulation of ion transport" BROAD [] is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006811 ! monoatomic ion transport relationship: regulates GO:0006811 ! monoatomic ion transport [Term] id: GO:0043270 name: positive regulation of monoatomic ion transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl] synonym: "activation of ion transport" NARROW [] synonym: "stimulation of ion transport" NARROW [] synonym: "up regulation of ion transport" EXACT [] synonym: "up-regulation of ion transport" EXACT [] synonym: "upregulation of ion transport" EXACT [] is_a: GO:0043269 ! regulation of monoatomic ion transport is_a: GO:0051050 ! positive regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006811 ! monoatomic ion transport relationship: positively_regulates GO:0006811 ! monoatomic ion transport [Term] id: GO:0043271 name: negative regulation of monoatomic ion transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl] synonym: "down regulation of ion transport" EXACT [] synonym: "down-regulation of ion transport" EXACT [] synonym: "downregulation of ion transport" EXACT [] synonym: "inhibition of ion transport" NARROW [] synonym: "negative regulation of ion transport" BROAD [] is_a: GO:0043269 ! regulation of monoatomic ion transport is_a: GO:0051051 ! negative regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006811 ! monoatomic ion transport relationship: negatively_regulates GO:0006811 ! monoatomic ion transport [Term] id: GO:0043279 name: response to alkaloid namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active." [GOC:jl] is_a: GO:0010243 ! response to organonitrogen compound intersection_of: GO:0050896 ! response to stimulus intersection_of: has_primary_input CHEBI:22315 ! alkaloid relationship: has_primary_input CHEBI:22315 ! alkaloid [Term] id: GO:0043292 name: contractile fiber namespace: cellular_component def: "Fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle." [GOC:go_curators, ISBN:0815316194] synonym: "contractile fibre" EXACT [] is_a: GO:0043232 ! intracellular non-membrane-bounded organelle is_a: GO:0099512 ! supramolecular fiber is_a: UBERON:0004120 ! mesoderm-derived structure relationship: part_of CL:0000187 ! muscle cell relationship: part_of GO:0005737 ! cytoplasm [Term] id: GO:0043353 name: enucleate erythrocyte differentiation namespace: biological_process def: "The process in which a myeloid precursor cell acquires specialized features of an erythrocyte without a nucleus. An example of this process is found in Mus musculus." [GOC:go_curators] synonym: "enucleate RBC differentiation" EXACT [CL:0000232] synonym: "enucleate red blood cell differentiation" EXACT [CL:0000232] is_a: GO:0030218 ! erythrocyte differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000595 ! enucleate erythrocyte relationship: results_in_acquisition_of_features_of CL:0000595 ! enucleate erythrocyte [Term] id: GO:0043354 name: enucleate erythrocyte maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for an enucleate erythrocyte to attain its fully functional state. An enucleate erythrocyte is an erythrocyte without a nucleus." [GOC:go_curators] synonym: "enucleate RBC maturation" EXACT [CL:0000232] synonym: "enucleate red blood cell maturation" EXACT [CL:0000232] is_a: GO:0043249 ! erythrocyte maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of CL:0000595 ! enucleate erythrocyte relationship: part_of GO:0048822 ! enucleate erythrocyte development relationship: results_in_maturation_of CL:0000595 ! enucleate erythrocyte [Term] id: GO:0043362 name: nucleate erythrocyte maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for a nucleate erythrocyte to attain its fully functional state. A nucleate erythrocyte is an erythrocyte with a nucleus." [GOC:devbiol, GOC:jl] synonym: "nucleate RBC maturation" EXACT [CL:0000232] synonym: "nucleate red blood cell maturation" EXACT [CL:0000232] is_a: GO:0043249 ! erythrocyte maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of CL:0000562 ! nucleate erythrocyte relationship: part_of GO:0048823 ! nucleate erythrocyte development relationship: results_in_maturation_of CL:0000562 ! nucleate erythrocyte [Term] id: GO:0043363 name: nucleate erythrocyte differentiation namespace: biological_process def: "The process in which a myeloid precursor cell acquires specializes features of an erythrocyte with a nucleus, as found in non-mammalian vertebrates such as birds." [GOC:jl] synonym: "nucleate RBC differentiation" EXACT [CL:0000232] synonym: "nucleate red blood cell differentiation" EXACT [CL:0000232] is_a: GO:0030218 ! erythrocyte differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000562 ! nucleate erythrocyte relationship: results_in_acquisition_of_features_of CL:0000562 ! nucleate erythrocyte [Term] id: GO:0043434 name: response to peptide hormone namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals." [PMID:11027914, PMID:15134857, Wikipedia:Peptide_hormone] synonym: "response to peptide hormone stimulus" EXACT [GOC:dos] synonym: "response to polypeptide hormone stimulus" EXACT [] is_a: GO:0009725 ! response to hormone is_a: GO:1901652 ! response to peptide intersection_of: GO:0050896 ! response to stimulus intersection_of: has_primary_input CHEBI:25905 ! peptide hormone relationship: has_primary_input CHEBI:25905 ! peptide hormone [Term] id: GO:0043436 name: oxoacid metabolic process namespace: biological_process def: "The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons)." [Wikipedia:Oxyacid] synonym: "keto acid metabolic process" EXACT [] synonym: "keto acid metabolism" EXACT [] synonym: "ketoacid metabolic process" EXACT [] synonym: "ketoacid metabolism" EXACT [] synonym: "oxo acid metabolic process" EXACT [] synonym: "oxo acid metabolism" EXACT [] synonym: "oxoacid metabolism" EXACT [] is_a: GO:0006082 ! organic acid metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:35406 ! oxoanion relationship: has_primary_input_or_output CHEBI:35406 ! oxoanion [Term] id: GO:0043455 name: regulation of secondary metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of secondary metabolism, the chemical reactions and pathways involving compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon." [GOC:jl] synonym: "regulation of secondary metabolism" EXACT [] is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0019748 ! secondary metabolic process relationship: regulates GO:0019748 ! secondary metabolic process [Term] id: GO:0043467 name: regulation of generation of precursor metabolites and energy namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and the processes involved in the liberation of energy from these substances." [GOC:jl] is_a: GO:0031323 ! regulation of cellular metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006091 ! generation of precursor metabolites and energy relationship: regulates GO:0006091 ! generation of precursor metabolites and energy [Term] id: GO:0043470 name: regulation of carbohydrate catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates." [GOC:mlg] is_a: GO:0006109 ! regulation of carbohydrate metabolic process is_a: GO:0009894 ! regulation of catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0016052 ! carbohydrate catabolic process relationship: regulates GO:0016052 ! carbohydrate catabolic process [Term] id: GO:0043473 name: pigmentation namespace: biological_process def: "The accumulation of pigment in an organism, tissue or cell, either by increased deposition or by increased number of cells." [GOC:jl] subset: goslim_chembl subset: goslim_pir is_a: GO:0008150 ! biological process relationship: in_taxon NCBITaxon:131567 {all_only="true"} ! cellular organisms relationship: only_in_taxon NCBITaxon:131567 ! cellular organisms [Term] id: GO:0043500 name: muscle adaptation namespace: biological_process def: "A process in which muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities." [GOC:mtg_muscle, PMID:11181628, PMID:11449884, PMID:12605307] subset: goslim_pir synonym: "muscle plasticity" RELATED [] is_a: GO:0003012 ! muscle system process is_a: GO:0050896 ! response to stimulus relationship: occurs_in UBERON:0002385 ! muscle tissue [Term] id: GO:0043501 name: skeletal muscle adaptation namespace: biological_process def: "Any process in which skeletal muscles change their phenotypic profiles in response to altered functional demands and a variety of signals." [GOC:mtg_muscle, PMID:11181628, PMID:11449884, PMID:12605307] synonym: "skeletal muscle plasticity" RELATED [] is_a: GO:0014888 ! striated muscle adaptation intersection_of: GO:0043500 ! muscle adaptation intersection_of: occurs_in UBERON:0001134 ! skeletal muscle tissue relationship: occurs_in UBERON:0001134 ! skeletal muscle tissue [Term] id: GO:0043502 name: regulation of muscle adaptation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of muscle adaptation." [GOC:go_curators, GOC:mtg_muscle] synonym: "regulation of muscle plasticity" RELATED [] is_a: GO:0048583 ! regulation of response to stimulus is_a: GO:0090257 ! regulation of muscle system process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0043500 ! muscle adaptation relationship: regulates GO:0043500 ! muscle adaptation [Term] id: GO:0043523 name: regulation of neuron apoptotic process namespace: biological_process def: "Any process that modulates the occurrence or rate of cell death by apoptotic process in neurons." [GOC:go_curators, GOC:mtg_apoptosis] synonym: "regulation of apoptosis of neuronal cells" EXACT [] synonym: "regulation of apoptosis of neurons" EXACT [] synonym: "regulation of neuron apoptosis" NARROW [] synonym: "regulation of neuron programmed cell death" EXACT [] synonym: "regulation of neuronal cell programmed cell death" EXACT [] synonym: "regulation of programmed cell death of neuronal cells" EXACT [] synonym: "regulation of programmed cell death, neurons" EXACT [] is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0051402 ! neuron apoptotic process relationship: regulates GO:0051402 ! neuron apoptotic process [Term] id: GO:0043524 name: negative regulation of neuron apoptotic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons." [GOC:go_curators, GOC:mtg_apoptosis] synonym: "down regulation of neuron apoptosis" EXACT [] synonym: "down-regulation of neuron apoptosis" EXACT [] synonym: "downregulation of neuron apoptosis" EXACT [] synonym: "inhibition of neuron apoptosis" NARROW [] synonym: "negative regulation of neuron apoptosis" NARROW [] synonym: "negative regulation of programmed cell death, neurons" EXACT [] synonym: "neuron survival" NARROW [] is_a: GO:0043066 ! negative regulation of apoptotic process is_a: GO:0043523 ! regulation of neuron apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0051402 ! neuron apoptotic process relationship: negatively_regulates GO:0051402 ! neuron apoptotic process [Term] id: GO:0043525 name: positive regulation of neuron apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process." [GOC:go_curators, GOC:mtg_apoptosis] synonym: "activation of neuron apoptosis" NARROW [] synonym: "positive regulation of neuron apoptosis" NARROW [] synonym: "positive regulation of programmed cell death, neurons" EXACT [] synonym: "stimulation of neuron apoptosis" NARROW [] synonym: "up regulation of neuron apoptosis" EXACT [] synonym: "up-regulation of neuron apoptosis" EXACT [] synonym: "upregulation of neuron apoptosis" EXACT [] is_a: GO:0043065 ! positive regulation of apoptotic process is_a: GO:0043523 ! regulation of neuron apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0051402 ! neuron apoptotic process relationship: positively_regulates GO:0051402 ! neuron apoptotic process [Term] id: GO:0043534 name: blood vessel endothelial cell migration namespace: biological_process def: "The orderly movement of an endothelial cell into the extracellular matrix in order to form new blood vessels during angiogenesis." [PMID:11166264] is_a: GO:0043542 ! endothelial cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000071 ! blood vessel endothelial cell relationship: results_in_movement_of CL:0000071 ! blood vessel endothelial cell [Term] id: GO:0043535 name: regulation of blood vessel endothelial cell migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the migration of the endothelial cells of blood vessels." [GOC:go_curators] is_a: GO:0010594 ! regulation of endothelial cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0043534 ! blood vessel endothelial cell migration relationship: regulates GO:0043534 ! blood vessel endothelial cell migration [Term] id: GO:0043536 name: positive regulation of blood vessel endothelial cell migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels." [GOC:go_curators] synonym: "activation of blood vessel endothelial cell migration" NARROW [] synonym: "stimulation of blood vessel endothelial cell migration" NARROW [] synonym: "up regulation of blood vessel endothelial cell migration" EXACT [] synonym: "up-regulation of blood vessel endothelial cell migration" EXACT [] synonym: "upregulation of blood vessel endothelial cell migration" EXACT [] is_a: GO:0010595 ! positive regulation of endothelial cell migration is_a: GO:0043535 ! regulation of blood vessel endothelial cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0043534 ! blood vessel endothelial cell migration relationship: positively_regulates GO:0043534 ! blood vessel endothelial cell migration [Term] id: GO:0043537 name: negative regulation of blood vessel endothelial cell migration namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the migration of the endothelial cells of blood vessels." [GOC:go_curators] synonym: "down regulation of blood vessel endothelial cell migration" EXACT [] synonym: "down-regulation of blood vessel endothelial cell migration" EXACT [] synonym: "downregulation of blood vessel endothelial cell migration" EXACT [] synonym: "inhibition of blood vessel endothelial cell migration" NARROW [] is_a: GO:0010596 ! negative regulation of endothelial cell migration is_a: GO:0043535 ! regulation of blood vessel endothelial cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0043534 ! blood vessel endothelial cell migration relationship: negatively_regulates GO:0043534 ! blood vessel endothelial cell migration [Term] id: GO:0043542 name: endothelial cell migration namespace: biological_process def: "The orderly movement of an endothelial cell into the extracellular matrix to form an endothelium." [GOC:go_curators] is_a: GO:0010631 ! epithelial cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000115 ! endothelial cell relationship: results_in_movement_of CL:0000115 ! endothelial cell [Term] id: GO:0043549 name: regulation of kinase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." [GOC:bf] subset: gocheck_do_not_annotate is_a: GO:0042325 ! regulation of phosphorylation is_a: GO:0051338 ! regulation of transferase activity intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0016301 ! kinase activity relationship: regulates GO:0016301 ! kinase activity [Term] id: GO:0043576 name: regulation of respiratory gaseous exchange namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the process of gaseous exchange between an organism and its environment." [GOC:jl] is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007585 ! respiratory gaseous exchange by respiratory system relationship: regulates GO:0007585 ! respiratory gaseous exchange by respiratory system [Term] id: GO:0043588 name: skin development namespace: biological_process def: "The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue." [GOC:jl, UBERON:0002097] synonym: "animal skin development" EXACT [] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002097 ! skin of body relationship: results_in_development_of UBERON:0002097 ! skin of body property_value: RO:0002161 NCBITaxon:50557 property_value: RO:0002161 NCBITaxon:6656 [Term] id: GO:0043589 name: skin morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the skin are generated and organized. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner, sensitive and vascular dermis (cutis, corium or true skin) composed mostly of connective tissue." [GOC:jl, UBERON:0002097] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002097 ! skin of body relationship: part_of GO:0043588 ! skin development relationship: results_in_morphogenesis_of UBERON:0002097 ! skin of body [Term] id: GO:0043603 name: amide metabolic process namespace: biological_process def: "The chemical reactions and pathways involving an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group, as carried out by individual cells." [GOC:curators] subset: goslim_pir synonym: "amide metabolism" EXACT [] synonym: "cellular amide metabolic process" EXACT [] is_a: GO:0006807 ! nitrogen compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:32988 ! amide relationship: has_primary_input_or_output CHEBI:32988 ! amide [Term] id: GO:0043604 name: amide biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group." [GOC:curators] is_a: GO:0043603 ! amide metabolic process is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:32988 ! amide relationship: has_primary_output CHEBI:32988 ! amide [Term] id: GO:0043605 name: amide catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group." [GOC:curators] synonym: "cellular amide catabolic process" EXACT [] is_a: GO:0009056 ! catabolic process is_a: GO:0043603 ! amide metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_output CHEBI:32988 ! amide relationship: has_primary_output CHEBI:32988 ! amide [Term] id: GO:0043648 name: dicarboxylic acid metabolic process namespace: biological_process def: "The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing two carboxyl (COOH) groups or anions (COO-)." [ISBN:0198506732] synonym: "dicarboxylate metabolic process" EXACT [] synonym: "dicarboxylate metabolism" EXACT [] synonym: "dicarboxylic acid metabolism" EXACT [] is_a: GO:0019752 ! carboxylic acid metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:35693 ! dicarboxylic acid anion relationship: has_primary_input_or_output CHEBI:35693 ! dicarboxylic acid anion [Term] id: GO:0043649 name: dicarboxylic acid catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups." [ISBN:0198506732] synonym: "dicarboxylate catabolic process" EXACT [] synonym: "dicarboxylate catabolism" EXACT [] synonym: "dicarboxylic acid breakdown" EXACT [] synonym: "dicarboxylic acid catabolism" EXACT [] synonym: "dicarboxylic acid degradation" EXACT [] is_a: GO:0043648 ! dicarboxylic acid metabolic process is_a: GO:0046395 ! carboxylic acid catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:35693 ! dicarboxylic acid anion relationship: has_primary_input CHEBI:35693 ! dicarboxylic acid anion [Term] id: GO:0043650 name: dicarboxylic acid biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups." [ISBN:0198506732] synonym: "dicarboxylate biosynthesis" EXACT [] synonym: "dicarboxylate biosynthetic process" EXACT [] synonym: "dicarboxylic acid anabolism" EXACT [] synonym: "dicarboxylic acid biosynthesis" EXACT [] synonym: "dicarboxylic acid formation" EXACT [] synonym: "dicarboxylic acid synthesis" EXACT [] is_a: GO:0043648 ! dicarboxylic acid metabolic process is_a: GO:0046394 ! carboxylic acid biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:35693 ! dicarboxylic acid anion relationship: has_primary_output CHEBI:35693 ! dicarboxylic acid anion [Term] id: GO:0043931 name: ossification involved in bone maturation namespace: biological_process def: "The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in the progression of the skeleton from its formation to its mature state." [GOC:dph, GOC:mah, GOC:mtg_mpo] synonym: "ossification involved in bone modeling" NARROW [GO_REF:0000034] synonym: "ossification involved in skeletal development" EXACT [GOC:dph] is_a: GO:0001503 ! ossification intersection_of: GO:0001503 ! ossification intersection_of: part_of GO:0070977 ! bone maturation relationship: part_of GO:0070977 ! bone maturation [Term] id: GO:0043933 name: protein-containing complex organization namespace: biological_process alt_id: GO:0034600 alt_id: GO:0034621 alt_id: GO:0071822 def: "Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex." [GOC:mah] synonym: "cellular macromolecular complex organization" RELATED [] synonym: "cellular macromolecular complex subunit organisation" RELATED [] synonym: "cellular macromolecular complex subunit organization" RELATED [] synonym: "macromolecular complex organization" RELATED [] synonym: "macromolecular complex subunit organisation" RELATED [] synonym: "macromolecular complex subunit organization" RELATED [] synonym: "protein complex subunit organisation" EXACT [GOC:mah] synonym: "protein complex subunit organization" EXACT [] synonym: "protein-containing complex subunit organization" RELATED [] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0032991 ! protein-containing complex relationship: results_in_organization_of GO:0032991 ! protein-containing complex property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22580" xsd:anyURI created_by: mah creation_date: 2010-09-08T10:01:42Z [Term] id: GO:0044042 name: glucan metabolic process namespace: biological_process def: "The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues." [GOC:jl] synonym: "glucan metabolism" EXACT [] is_a: GO:0005976 ! polysaccharide metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:37163 ! glucan relationship: has_primary_input_or_output CHEBI:37163 ! glucan [Term] id: GO:0044057 name: regulation of system process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system." [GOC:jl] is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003008 ! system process relationship: regulates GO:0003008 ! system process [Term] id: GO:0044058 name: regulation of digestive system process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." [GOC:jl] is_a: GO:0044057 ! regulation of system process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0022600 ! digestive system process relationship: regulates GO:0022600 ! digestive system process [Term] id: GO:0044060 name: regulation of endocrine process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of an endocrine process, a process involving the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system." [GOC:jl] synonym: "regulation of endocrine system process" EXACT [] is_a: GO:0044057 ! regulation of system process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0050886 ! endocrine process relationship: regulates GO:0050886 ! endocrine process [Term] id: GO:0044062 name: regulation of excretion namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of excretion, the elimination by an organism of the waste products that arise as a result of metabolic activity." [GOC:jl] is_a: GO:0044057 ! regulation of system process is_a: GO:0051046 ! regulation of secretion intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007588 ! excretion relationship: regulates GO:0007588 ! excretion [Term] id: GO:0044065 name: regulation of respiratory system process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a respiratory system process, an organ system process carried out by any of the organs or tissues of the respiratory system." [GOC:jl] is_a: GO:0043576 ! regulation of respiratory gaseous exchange is_a: GO:0044057 ! regulation of system process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003016 ! respiratory system process relationship: regulates GO:0003016 ! respiratory system process [Term] id: GO:0044085 name: cellular component biogenesis namespace: biological_process alt_id: GO:0071843 def: "A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component." [GOC:jl, GOC:mah] subset: goslim_pir synonym: "cellular component biogenesis at cellular level" EXACT [] is_a: GO:0071840 ! cellular component organization or biogenesis [Term] id: GO:0044087 name: regulation of cellular component biogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component." [GOC:jl] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0044085 ! cellular component biogenesis relationship: regulates GO:0044085 ! cellular component biogenesis [Term] id: GO:0044088 name: regulation of vacuole organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole." [GOC:jl, GOC:mah] synonym: "regulation of vacuole biogenesis" RELATED [GOC:mah] synonym: "regulation of vacuole organisation" EXACT [GOC:mah] is_a: GO:0033043 ! regulation of organelle organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007033 ! vacuole organization relationship: regulates GO:0007033 ! vacuole organization [Term] id: GO:0044089 name: positive regulation of cellular component biogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component." [GOC:jl] is_a: GO:0044087 ! regulation of cellular component biogenesis is_a: GO:0048522 ! positive regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0044085 ! cellular component biogenesis relationship: positively_regulates GO:0044085 ! cellular component biogenesis [Term] id: GO:0044090 name: positive regulation of vacuole organization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole." [GOC:jl, GOC:mah] synonym: "positive regulation of vacuole biogenesis" RELATED [GOC:mah] synonym: "positive regulation of vacuole organisation" EXACT [GOC:mah] is_a: GO:0010638 ! positive regulation of organelle organization is_a: GO:0044088 ! regulation of vacuole organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007033 ! vacuole organization relationship: positively_regulates GO:0007033 ! vacuole organization [Term] id: GO:0044091 name: membrane biogenesis namespace: biological_process def: "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a membrane." [GOC:jl] is_a: GO:0044085 ! cellular component biogenesis intersection_of: GO:0044085 ! cellular component biogenesis intersection_of: has_primary_output GO:0016020 ! membrane relationship: has_primary_output GO:0016020 ! membrane [Term] id: GO:0044092 name: negative regulation of molecular function namespace: biological_process def: "Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding." [GO:jl] subset: gocheck_do_not_annotate is_a: GO:0065009 ! regulation of molecular function intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0003674 ! molecular_function relationship: negatively_regulates GO:0003674 ! molecular_function created_by: jl creation_date: 2009-04-21T04:07:27Z [Term] id: GO:0044093 name: positive regulation of molecular function namespace: biological_process def: "Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding." [GO:jl] subset: gocheck_do_not_annotate is_a: GO:0065009 ! regulation of molecular function intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0003674 ! molecular_function relationship: positively_regulates GO:0003674 ! molecular_function created_by: jl creation_date: 2009-04-21T04:11:06Z [Term] id: GO:0044207 name: translation initiation ternary complex namespace: cellular_component def: "A ribonucleoprotein complex that contains aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator)." [GOC:jl] synonym: "Met-tRNA/eIF2.GTP ternary complex" NARROW [] synonym: "translation initiation (ternary) complex" EXACT [] is_a: GO:1990904 ! ribonucleoprotein complex relationship: part_of GO:0005737 ! cytoplasm created_by: jl creation_date: 2009-10-22T02:38:55Z [Term] id: GO:0044237 name: cellular metabolic process namespace: biological_process def: "The chemical reactions and pathways by which individual cells transform chemical substances." [GOC:go_curators] comment: This term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term. subset: gocheck_do_not_annotate synonym: "cellular metabolism" EXACT [] synonym: "intermediary metabolism" RELATED [GOC:mah] is_a: GO:0008152 ! metabolic process is_a: GO:0009987 ! cellular process [Term] id: GO:0044238 name: primary metabolic process namespace: biological_process def: "The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism." [GOC:go_curators, http://www.metacyc.org] subset: gocheck_do_not_annotate subset: goslim_pir synonym: "primary metabolism" EXACT [] is_a: GO:0008152 ! metabolic process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI [Term] id: GO:0044248 name: cellular catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells." [GOC:jl] synonym: "cellular breakdown" EXACT [] synonym: "cellular catabolism" EXACT [] synonym: "cellular degradation" EXACT [] is_a: GO:0009056 ! catabolic process is_a: GO:0044237 ! cellular metabolic process [Term] id: GO:0044249 name: cellular biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." [GOC:jl] synonym: "cellular anabolism" EXACT [] synonym: "cellular biosynthesis" EXACT [] synonym: "cellular formation" EXACT [] synonym: "cellular synthesis" EXACT [] is_a: GO:0009058 ! biosynthetic process is_a: GO:0044237 ! cellular metabolic process [Term] id: GO:0044258 name: intestinal lipid catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown into fatty acids and monoglycerides of lipids in the small intestine. Lipids are broken down by lipases released by the pancreas." [GOC:jl, http://www.emc.maricopa.edu/] synonym: "intestinal lipid breakdown" EXACT [] synonym: "intestinal lipid catabolism" EXACT [] synonym: "intestinal lipid degradation" EXACT [] is_a: GO:0016042 ! lipid catabolic process intersection_of: GO:0016042 ! lipid catabolic process intersection_of: occurs_in UBERON:0000160 ! intestine relationship: occurs_in UBERON:0000160 ! intestine [Term] id: GO:0044270 name: cellular nitrogen compound catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of organic and inorganic nitrogenous compounds." [GOC:jl, ISBN:0198506732] synonym: "nitrogen compound breakdown" BROAD [] synonym: "nitrogen compound catabolism" BROAD [] synonym: "nitrogen compound degradation" BROAD [] is_a: GO:0034641 ! cellular nitrogen compound metabolic process is_a: GO:0044248 ! cellular catabolic process [Term] id: GO:0044271 name: cellular nitrogen compound biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of organic and inorganic nitrogenous compounds." [GOC:jl, ISBN:0198506732] synonym: "nitrogen compound anabolism" BROAD [] synonym: "nitrogen compound biosynthesis" BROAD [] synonym: "nitrogen compound formation" BROAD [] synonym: "nitrogen compound synthesis" BROAD [] is_a: GO:0034641 ! cellular nitrogen compound metabolic process is_a: GO:0044249 ! cellular biosynthetic process [Term] id: GO:0044272 name: sulfur compound biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione." [GOC:jl] synonym: "sulfur biosynthesis" NARROW [] synonym: "sulfur biosynthetic process" NARROW [] synonym: "sulfur compound anabolism" EXACT [] synonym: "sulfur compound biosynthesis" EXACT [] synonym: "sulfur compound formation" EXACT [] synonym: "sulfur compound synthesis" EXACT [] is_a: GO:0006790 ! sulfur compound metabolic process is_a: GO:0044249 ! cellular biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:26835 ! sulfur molecular entity relationship: has_primary_output CHEBI:26835 ! sulfur molecular entity [Term] id: GO:0044273 name: sulfur compound catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione." [GOC:jl] synonym: "sulfur catabolic process" NARROW [] synonym: "sulfur catabolism" NARROW [] synonym: "sulfur compound breakdown" EXACT [] synonym: "sulfur compound catabolism" EXACT [] synonym: "sulfur compound degradation" EXACT [] is_a: GO:0006790 ! sulfur compound metabolic process is_a: GO:0044248 ! cellular catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:26835 ! sulfur molecular entity relationship: has_primary_input CHEBI:26835 ! sulfur molecular entity [Term] id: GO:0044281 name: small molecule metabolic process namespace: biological_process def: "The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule." [GOC:curators, GOC:pde, GOC:vw] comment: Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides. subset: goslim_chembl subset: goslim_flybase_ribbon subset: goslim_metagenomics synonym: "small molecule metabolism" EXACT [] is_a: GO:0008152 ! metabolic process created_by: jl creation_date: 2010-01-26T12:05:20Z [Term] id: GO:0044282 name: small molecule catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of small molecules, any low molecular weight, monomeric, non-encoded molecule." [GOC:curators, GOC:vw] comment: Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides. synonym: "small molecule catabolism" EXACT [] is_a: GO:0009056 ! catabolic process is_a: GO:0044281 ! small molecule metabolic process created_by: jl creation_date: 2010-01-26T12:06:10Z [Term] id: GO:0044283 name: small molecule biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of small molecules, any low molecular weight, monomeric, non-encoded molecule." [GOC:curators, GOC:pde, GOC:vw] comment: Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides. subset: goslim_prokaryote synonym: "small molecule biosynthesis" EXACT [] is_a: GO:0009058 ! biosynthetic process is_a: GO:0044281 ! small molecule metabolic process created_by: jl creation_date: 2010-01-26T12:06:49Z [Term] id: GO:0044297 name: cell body namespace: cellular_component def: "The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections." [GOC:go_curators] comment: Note that 'cell body' and 'cell soma' are not used in the literature for cells that lack projections, nor for some cells (e.g. yeast with mating projections) that do have projections. synonym: "cell soma" EXACT [] xref: FBbt:00005107 xref: FMA:67301 xref: Wikipedia:Cell_body is_a: GO:0110165 ! cellular anatomical entity relationship: part_of CL:0000000 ! cell property_value: RO:0002161 NCBITaxon:4890 created_by: jl creation_date: 2010-02-05T10:37:16Z [Term] id: GO:0044342 name: type B pancreatic cell proliferation namespace: biological_process def: "The multiplication or reproduction of pancreatic B cells, resulting in the expansion of an pancreatic B cell population. Pancreatic B cell are cells of the pancreas that secrete insulin." [GOC:jl, GOC:yaf] synonym: "pancreatic B cell proliferation" EXACT [GOC:mah] synonym: "pancreatic beta cell proliferation" EXACT [] is_a: GO:0050673 ! epithelial cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000169 ! type B pancreatic cell relationship: acts_on_population_of CL:0000169 ! type B pancreatic cell created_by: jl creation_date: 2010-08-25T01:44:51Z [Term] id: GO:0044346 name: fibroblast apoptotic process namespace: biological_process def: "Any apoptotic process in a fibroblast, a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules." [CL:0000057, GOC:jl, GOC:mtg_apoptosis, GOC:yaf] synonym: "fibroblast apoptosis" NARROW [] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000057 ! fibroblast relationship: occurs_in CL:0000057 ! fibroblast created_by: jl creation_date: 2010-09-23T11:33:38Z [Term] id: GO:0044380 name: protein localization to cytoskeleton namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within the cytoskeleton." [GOC:jl] synonym: "protein localisation to cytoskeleton" EXACT [GOC:mah] is_a: GO:0033365 ! protein localization to organelle intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0005856 ! cytoskeleton relationship: has_target_end_location GO:0005856 ! cytoskeleton created_by: jl creation_date: 2011-12-13T11:43:24Z [Term] id: GO:0044419 name: biological process involved in interspecies interaction between organisms namespace: biological_process def: "Any process evolved to enable an interaction with an organism of a different species." [GOC:cc] subset: gocheck_do_not_annotate subset: goslim_candida subset: goslim_pir synonym: "interaction with another species" EXACT [] synonym: "interspecies interaction" EXACT [] synonym: "interspecies interaction between organisms" EXACT [] synonym: "interspecies interaction with other organisms" EXACT [] is_a: GO:0008150 ! biological process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/20191" xsd:anyURI property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0044458 name: motile cilium assembly namespace: biological_process alt_id: GO:1903887 def: "The aggregation, arrangement and bonding together of a set of components to form a motile cilium." [GO_REF:0000079, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:19776033, PMID:21129373, ZFIN:dsf] synonym: "motile primary cilia assembly" RELATED [GOC:TermGenie] synonym: "motile primary cilia formation" RELATED [GOC:TermGenie] synonym: "motile primary cilium assembly" RELATED [] synonym: "motile primary cilium formation" RELATED [GOC:TermGenie] synonym: "nodal cilium assembly" RELATED [GOC:TermGenie] synonym: "nodal cilium formation" RELATED [GOC:TermGenie] is_a: GO:0060271 ! cilium assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0031514 ! motile cilium relationship: results_in_assembly_of GO:0031514 ! motile cilium created_by: krc creation_date: 2015-02-06T17:23:23Z [Term] id: GO:0044550 name: secondary metabolite biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon." [GOC:jl] subset: goslim_prokaryote synonym: "secondary metabolite biosynthesis" EXACT [] is_a: GO:0009058 ! biosynthetic process is_a: GO:0019748 ! secondary metabolic process created_by: jl creation_date: 2012-03-29T01:55:18Z [Term] id: GO:0044565 name: dendritic cell proliferation namespace: biological_process def: "The expansion of a dendritic cell population by cell division. A dendritic cell is a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation." [CL:0000451, PMID:18469816] is_a: GO:0032943 ! mononuclear cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000451 ! dendritic cell relationship: acts_on_population_of CL:0000451 ! dendritic cell created_by: jl creation_date: 2012-04-05T04:31:39Z [Term] id: GO:0044566 name: chondrocyte activation namespace: biological_process def: "A change in the morphology or behavior of a chondrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. A chondrocyte is a polymorphic cell that forms cartilage." [CL:0000138, GOC:jl] is_a: GO:0001775 ! cell activation intersection_of: GO:0001775 ! cell activation intersection_of: has_primary_input CL:0000138 ! chondrocyte relationship: has_primary_input CL:0000138 ! chondrocyte created_by: jl creation_date: 2012-04-05T04:45:38Z [Term] id: GO:0044703 name: multi-organism reproductive process namespace: biological_process def: "A biological process that directly contributes to the process of producing new individuals, involving another organism." [GOC:jl] subset: goslim_drosophila is_a: GO:0022414 ! reproductive process created_by: jl creation_date: 2012-09-19T15:56:30Z [Term] id: GO:0044706 name: multi-multicellular organism process namespace: biological_process def: "A multicellular organism process which involves another multicellular organism of the same or different species." [GOC:jl] is_a: GO:0032501 ! multicellular organismal process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/21459" xsd:anyURI created_by: jl creation_date: 2012-09-19T16:06:16Z [Term] id: GO:0044782 name: cilium organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole." [GOC:cilia, GOC:jl] comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. subset: goslim_drosophila subset: goslim_generic synonym: "microtubule-based flagellum organization" EXACT [] is_a: GO:0006996 ! organelle organization is_a: GO:0120036 ! plasma membrane bounded cell projection organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0005929 ! cilium relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota relationship: results_in_organization_of GO:0005929 ! cilium created_by: jl creation_date: 2013-03-27T15:09:58Z [Term] id: GO:0045026 name: plasma membrane fusion namespace: biological_process alt_id: GO:0006947 def: "The joining of the lipid bilayer membrane that surround a cell with that of another cell, producing a single cell." [GOC:elh, GOC:mtg_muscle] synonym: "cell fusion" BROAD [] synonym: "cell-cell fusion" BROAD [] is_a: GO:0007009 ! plasma membrane organization is_a: GO:0061025 ! membrane fusion intersection_of: GO:0009987 ! cellular process intersection_of: results_in_fusion_of GO:0005886 ! plasma membrane relationship: results_in_fusion_of GO:0005886 ! plasma membrane [Term] id: GO:0045120 name: pronucleus namespace: cellular_component def: "The nucleus of either the ovum or the spermatozoon following fertilization. Thus, in the fertilized ovum, there are two pronuclei, one originating from the ovum, the other from the spermatozoon that brought about fertilization; they approach each other, but do not fuse until just before the first cleavage, when each pronucleus loses its membrane to release its contents." [ISBN:0198506732] xref: Wikipedia:Pronucleus is_a: GO:0005634 ! nucleus relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa [Term] id: GO:0045132 name: meiotic chromosome segregation namespace: biological_process def: "The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets during M phase of the meiotic cell cycle." [GOC:ai, GOC:mah] is_a: GO:0098813 ! nuclear chromosome segregation is_a: GO:1903046 ! meiotic cell cycle process intersection_of: GO:0098813 ! nuclear chromosome segregation intersection_of: part_of GO:0140013 ! meiotic nuclear division relationship: part_of GO:0140013 ! meiotic nuclear division [Term] id: GO:0045137 name: development of primary sexual characteristics namespace: biological_process def: "The process whose specific outcome is the progression of the primary sexual characteristics over time, from their formation to the mature structures. The primary sexual characteristics are the testes in males and the ovaries in females and they develop in response to sex hormone secretion." [GOC:ai] is_a: GO:0003006 ! developmental process involved in reproduction relationship: part_of GO:0007275 ! multicellular organism development relationship: part_of GO:0007548 ! sex differentiation [Term] id: GO:0045144 name: meiotic sister chromatid segregation namespace: biological_process def: "The cell cycle process in which sister chromatids are organized and then physically separated and randomly apportioned to two sets during the second division of the meiotic cell cycle." [GOC:ai, ISBN:0815316194] synonym: "meiosis II, chromosome segregation" EXACT [] is_a: GO:0000819 ! sister chromatid segregation is_a: GO:0045132 ! meiotic chromosome segregation is_a: GO:0070192 ! chromosome organization involved in meiotic cell cycle intersection_of: GO:0000819 ! sister chromatid segregation intersection_of: part_of GO:0007135 ! meiosis II relationship: part_of GO:0007135 ! meiosis II [Term] id: GO:0045165 name: cell fate commitment namespace: biological_process def: "The cellular developmental process by which a cell establishes the intrinsic character of a cell or tissue region irreversibly committing it to a particular fate." [ISBN:0716731185] comment: Note that this term was 'cell fate determination' but the term name was changed to better match its existing definition and the child term 'cell fate determination; GO:0001709' was also created. is_a: GO:0048869 ! cellular developmental process relationship: part_of GO:0030154 ! cell differentiation property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24390" xsd:anyURI [Term] id: GO:0045168 name: cell-cell signaling involved in cell fate commitment namespace: biological_process def: "Signaling at long or short range between cells that results in the commitment of a cell to a certain fate." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "cell fate commitment, cell-cell signaling" EXACT [] synonym: "cell fate commitment, cell-cell signalling" EXACT [] synonym: "cell-cell signaling during in cell fate commitment" EXACT [] synonym: "cell-cell signaling resulting in cell fate commitment" EXACT [] synonym: "cell-cell signalling during cell fate commitment" EXACT [] synonym: "cell-cell signalling involved in cell fate specification" NARROW [GOC:dph, GOC:tb] synonym: "cell-cell signalling resulting in cell fate commitment" EXACT [] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: part_of GO:0045165 ! cell fate commitment relationship: part_of GO:0045165 ! cell fate commitment [Term] id: GO:0045184 name: establishment of protein localization namespace: biological_process def: "The directed movement of a protein to a specific location." [GOC:bf] synonym: "establishment of protein localisation" EXACT [GOC:mah] synonym: "protein positioning" EXACT [] synonym: "protein recruitment" EXACT [] is_a: GO:0051234 ! establishment of localization intersection_of: GO:0051234 ! establishment of localization intersection_of: has_primary_input CHEBI:36080 ! protein relationship: has_primary_input CHEBI:36080 ! protein [Term] id: GO:0045196 name: establishment or maintenance of neuroblast polarity namespace: biological_process alt_id: GO:0043339 alt_id: GO:0043342 def: "Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system." [GOC:bf, GOC:mah, GOC:mtg_sensu, PMID:19375318, PMID:20066083] synonym: "establishment and/or maintenance of neuroblast cell polarity" EXACT [] is_a: GO:0007163 ! establishment or maintenance of cell polarity relationship: part_of GO:0055059 ! asymmetric neuroblast division [Term] id: GO:0045200 name: establishment of neuroblast polarity namespace: biological_process alt_id: GO:0043340 alt_id: GO:0043343 def: "The specification and formation of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system." [GOC:bf, GOC:mtg_sensu] synonym: "establishment of neuroblast cell polarity" EXACT [] is_a: GO:0030010 ! establishment of cell polarity is_a: GO:0045196 ! establishment or maintenance of neuroblast polarity intersection_of: GO:0030010 ! establishment of cell polarity intersection_of: occurs_in CL:0000031 ! neuroblast (sensu Vertebrata) relationship: occurs_in CL:0000031 ! neuroblast (sensu Vertebrata) [Term] id: GO:0045202 name: synapse namespace: cellular_component def: "The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane." [GOC:aruk, ISBN:0198506732, PMID:24619342, PMID:29383328, PMID:31998110] subset: goslim_agr subset: goslim_drosophila subset: goslim_flybase_ribbon subset: goslim_mouse subset: goslim_pir subset: goslim_synapse synonym: "electrotonic synapse" RELATED [NIF_Subcellular:sao1311109124] synonym: "mixed synapse" NARROW [NIF_Subcellular:sao1506103497] synonym: "synaptic junction" EXACT [] xref: NIF_Subcellular:sao914572699 xref: Wikipedia:Chemical_synapse is_a: GO:0030054 ! cell junction relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa [Term] id: GO:0045214 name: sarcomere organization namespace: biological_process alt_id: GO:0006938 def: "The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." [GOC:bf] synonym: "sarcomere alignment" EXACT [] synonym: "sarcomere organisation" EXACT [] is_a: GO:0031032 ! actomyosin structure organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0030017 ! sarcomere relationship: part_of GO:0030239 ! myofibril assembly relationship: results_in_organization_of GO:0030017 ! sarcomere [Term] id: GO:0045216 name: cell-cell junction organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-cell junction. A cell-cell junction is a specialized region of connection between two cells." [GOC:ai, GOC:dph, GOC:jl, GOC:mah] synonym: "cell-cell junction assembly and maintenance" EXACT [] synonym: "cell-cell junction biogenesis" RELATED [] synonym: "cell-cell junction organisation" EXACT [GOC:mah] synonym: "intercellular junction assembly and maintenance" EXACT [] is_a: GO:0034330 ! cell junction organization intersection_of: GO:0034330 ! cell junction organization intersection_of: results_in_organization_of GO:0005911 ! cell-cell junction relationship: results_in_organization_of GO:0005911 ! cell-cell junction [Term] id: GO:0045222 name: CD4 biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of CD4, a CD marker that occurs on T-helper cells and is involved in MHC class II restricted interactions." [GOC:go_curators, ISBN:0198506732] synonym: "CD4 anabolism" EXACT [] synonym: "CD4 biosynthesis" EXACT [] synonym: "CD4 formation" EXACT [] synonym: "CD4 synthesis" EXACT [] is_a: GO:0009101 ! glycoprotein biosynthetic process is_a: GO:0019538 ! protein metabolic process is_a: GO:1901566 ! organonitrogen compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output PR:000001004 ! CD4 molecule relationship: has_primary_output PR:000001004 ! CD4 molecule [Term] id: GO:0045223 name: regulation of CD4 production namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4." [GOC:go_curators] synonym: "regulation of CD4 anabolism" EXACT [] synonym: "regulation of CD4 biosynthesis" EXACT [] synonym: "regulation of CD4 biosynthetic process" EXACT [] synonym: "regulation of CD4 formation" EXACT [] synonym: "regulation of CD4 synthesis" EXACT [] is_a: GO:0010559 ! regulation of glycoprotein biosynthetic process is_a: GO:0051246 ! regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0045222 ! CD4 biosynthetic process relationship: regulates GO:0045222 ! CD4 biosynthetic process [Term] id: GO:0045224 name: positive regulation of CD4 production namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4." [GOC:go_curators] synonym: "activation of CD4 biosynthetic process" NARROW [] synonym: "positive regulation of CD4 anabolism" EXACT [] synonym: "positive regulation of CD4 biosynthesis" EXACT [] synonym: "positive regulation of CD4 biosynthetic process" EXACT [] synonym: "positive regulation of CD4 formation" EXACT [] synonym: "positive regulation of CD4 synthesis" EXACT [] synonym: "stimulation of CD4 biosynthetic process" NARROW [] synonym: "up regulation of CD4 biosynthetic process" EXACT [] synonym: "up-regulation of CD4 biosynthetic process" EXACT [] synonym: "upregulation of CD4 biosynthetic process" EXACT [] is_a: GO:0010560 ! positive regulation of glycoprotein biosynthetic process is_a: GO:0045223 ! regulation of CD4 production is_a: GO:0051247 ! positive regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0045222 ! CD4 biosynthetic process relationship: positively_regulates GO:0045222 ! CD4 biosynthetic process [Term] id: GO:0045225 name: negative regulation of CD4 production namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4." [GOC:go_curators] synonym: "down regulation of CD4 biosynthetic process" EXACT [] synonym: "down-regulation of CD4 biosynthetic process" EXACT [] synonym: "downregulation of CD4 biosynthetic process" EXACT [] synonym: "inhibition of CD4 biosynthetic process" NARROW [] synonym: "negative regulation of CD4 anabolism" EXACT [] synonym: "negative regulation of CD4 biosynthesis" EXACT [] synonym: "negative regulation of CD4 biosynthetic process" EXACT [] synonym: "negative regulation of CD4 formation" EXACT [] synonym: "negative regulation of CD4 synthesis" EXACT [] is_a: GO:0010561 ! negative regulation of glycoprotein biosynthetic process is_a: GO:0045223 ! regulation of CD4 production is_a: GO:0051248 ! negative regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0045222 ! CD4 biosynthetic process relationship: negatively_regulates GO:0045222 ! CD4 biosynthetic process [Term] id: GO:0045229 name: external encapsulating structure organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of external structures that lie outside the plasma membrane and surround the entire cell." [GOC:ai, GOC:dph, GOC:jl, GOC:mah] subset: goslim_pir synonym: "external encapsulating structure organisation" EXACT [] synonym: "external encapsulating structure organization and biogenesis" EXACT [GOC:dph, GOC:jl, GOC:mah] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0030312 ! external encapsulating structure relationship: results_in_organization_of GO:0030312 ! external encapsulating structure [Term] id: GO:0045321 name: leukocyte activation namespace: biological_process def: "A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor." [GOC:add] synonym: "immune cell activation" EXACT [] synonym: "leucocyte activation" EXACT [] xref: Wikipedia:Immunologic_activation is_a: GO:0001775 ! cell activation is_a: GO:0002376 ! immune system process intersection_of: GO:0001775 ! cell activation intersection_of: has_primary_input CL:0000738 ! leukocyte relationship: has_primary_input CL:0000738 ! leukocyte relationship: in_taxon NCBITaxon:7742 {all_only="true"} ! Vertebrata relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata [Term] id: GO:0045444 name: fat cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat." [CL:0000136, GOC:go_curators] synonym: "adipocyte cell differentiation" EXACT [] synonym: "adipocyte differentiation" EXACT [] synonym: "adipogenesis" RELATED [] synonym: "adipose cell differentiation" EXACT [] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000136 ! adipocyte relationship: results_in_acquisition_of_features_of CL:0000136 ! adipocyte [Term] id: GO:0045445 name: myoblast differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers." [CL:0000056, GOC:go_curators, GOC:mtg_muscle] synonym: "myoblast cell differentiation" EXACT [] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000056 ! myoblast relationship: part_of GO:0061061 ! muscle structure development relationship: results_in_acquisition_of_features_of CL:0000056 ! myoblast [Term] id: GO:0045446 name: endothelial cell differentiation namespace: biological_process def: "The process in which a mesodermal, bone marrow or neural crest cell acquires specialized features of an endothelial cell, a thin flattened cell. A layer of such cells lines the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium." [CL:0000115, GOC:go_curators] is_a: GO:0030855 ! epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000115 ! endothelial cell relationship: part_of GO:0003158 ! endothelium development relationship: results_in_acquisition_of_features_of CL:0000115 ! endothelial cell [Term] id: GO:0045580 name: regulation of T cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of T cell differentiation." [GOC:go_curators] comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. synonym: "regulation of T cell development" RELATED [GOC:add] synonym: "regulation of T lymphocyte differentiation" EXACT [] synonym: "regulation of T-cell differentiation" EXACT [] synonym: "regulation of T-lymphocyte differentiation" EXACT [] is_a: GO:0045619 ! regulation of lymphocyte differentiation is_a: GO:0050863 ! regulation of T cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030217 ! T cell differentiation relationship: regulates GO:0030217 ! T cell differentiation [Term] id: GO:0045581 name: negative regulation of T cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation." [GOC:go_curators] comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. synonym: "down regulation of T cell differentiation" EXACT [] synonym: "down-regulation of T cell differentiation" EXACT [] synonym: "downregulation of T cell differentiation" EXACT [] synonym: "inhibition of T cell differentiation" NARROW [] synonym: "negative regulation of T cell development" RELATED [GOC:add] synonym: "negative regulation of T lymphocyte differentiation" EXACT [] synonym: "negative regulation of T-cell differentiation" EXACT [] synonym: "negative regulation of T-lymphocyte differentiation" EXACT [] is_a: GO:0045580 ! regulation of T cell differentiation is_a: GO:0045620 ! negative regulation of lymphocyte differentiation is_a: GO:0050868 ! negative regulation of T cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030217 ! T cell differentiation relationship: negatively_regulates GO:0030217 ! T cell differentiation [Term] id: GO:0045582 name: positive regulation of T cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of T cell differentiation." [GOC:go_curators] comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. synonym: "activation of T cell differentiation" NARROW [] synonym: "positive regulation of T cell development" RELATED [GOC:add] synonym: "positive regulation of T lymphocyte differentiation" EXACT [] synonym: "positive regulation of T-cell differentiation" EXACT [] synonym: "positive regulation of T-lymphocyte differentiation" EXACT [] synonym: "stimulation of T cell differentiation" NARROW [] synonym: "up regulation of T cell differentiation" EXACT [] synonym: "up-regulation of T cell differentiation" EXACT [] synonym: "upregulation of T cell differentiation" EXACT [] is_a: GO:0045580 ! regulation of T cell differentiation is_a: GO:0045621 ! positive regulation of lymphocyte differentiation is_a: GO:0050870 ! positive regulation of T cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030217 ! T cell differentiation relationship: positively_regulates GO:0030217 ! T cell differentiation [Term] id: GO:0045595 name: regulation of cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features." [GOC:go_curators] is_a: GO:0050793 ! regulation of developmental process is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030154 ! cell differentiation relationship: regulates GO:0030154 ! cell differentiation [Term] id: GO:0045596 name: negative regulation of cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation." [GOC:go_curators] synonym: "down regulation of cell differentiation" EXACT [] synonym: "down-regulation of cell differentiation" EXACT [] synonym: "downregulation of cell differentiation" EXACT [] synonym: "inhibition of cell differentiation" NARROW [] is_a: GO:0045595 ! regulation of cell differentiation is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:0051093 ! negative regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030154 ! cell differentiation relationship: negatively_regulates GO:0030154 ! cell differentiation [Term] id: GO:0045597 name: positive regulation of cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell differentiation." [GOC:go_curators] synonym: "activation of cell differentiation" NARROW [] synonym: "stimulation of cell differentiation" NARROW [] synonym: "up regulation of cell differentiation" EXACT [] synonym: "up-regulation of cell differentiation" EXACT [] synonym: "upregulation of cell differentiation" EXACT [] is_a: GO:0045595 ! regulation of cell differentiation is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:0051094 ! positive regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030154 ! cell differentiation relationship: positively_regulates GO:0030154 ! cell differentiation [Term] id: GO:0045598 name: regulation of fat cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of adipocyte differentiation." [GOC:go_curators] synonym: "regulation of adipocyte cell differentiation" EXACT [] synonym: "regulation of adipocyte differentiation" EXACT [] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0045444 ! fat cell differentiation relationship: regulates GO:0045444 ! fat cell differentiation [Term] id: GO:0045599 name: negative regulation of fat cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of adipocyte differentiation." [GOC:go_curators] synonym: "down regulation of fat cell differentiation" EXACT [] synonym: "down-regulation of fat cell differentiation" EXACT [] synonym: "downregulation of fat cell differentiation" EXACT [] synonym: "inhibition of fat cell differentiation" NARROW [] synonym: "negative regulation of adipocyte cell differentiation" EXACT [] synonym: "negative regulation of adipocyte differentiation" EXACT [] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0045598 ! regulation of fat cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0045444 ! fat cell differentiation relationship: negatively_regulates GO:0045444 ! fat cell differentiation [Term] id: GO:0045600 name: positive regulation of fat cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of adipocyte differentiation." [GOC:go_curators] synonym: "activation of fat cell differentiation" NARROW [] synonym: "positive regulation of adipocyte cell differentiation" EXACT [] synonym: "positive regulation of adipocyte differentiation" EXACT [] synonym: "stimulation of fat cell differentiation" NARROW [] synonym: "up regulation of fat cell differentiation" EXACT [] synonym: "up-regulation of fat cell differentiation" EXACT [] synonym: "upregulation of fat cell differentiation" EXACT [] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0045598 ! regulation of fat cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0045444 ! fat cell differentiation relationship: positively_regulates GO:0045444 ! fat cell differentiation [Term] id: GO:0045601 name: regulation of endothelial cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of endothelial cell differentiation." [GOC:go_curators] is_a: GO:0030856 ! regulation of epithelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0045446 ! endothelial cell differentiation relationship: regulates GO:0045446 ! endothelial cell differentiation [Term] id: GO:0045602 name: negative regulation of endothelial cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of endothelial cell differentiation." [GOC:go_curators] synonym: "down regulation of endothelial cell differentiation" EXACT [] synonym: "down-regulation of endothelial cell differentiation" EXACT [] synonym: "downregulation of endothelial cell differentiation" EXACT [] synonym: "inhibition of endothelial cell differentiation" NARROW [] is_a: GO:0030857 ! negative regulation of epithelial cell differentiation is_a: GO:0045601 ! regulation of endothelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0045446 ! endothelial cell differentiation relationship: negatively_regulates GO:0045446 ! endothelial cell differentiation [Term] id: GO:0045603 name: positive regulation of endothelial cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of endothelial cell differentiation." [GOC:go_curators] synonym: "activation of endothelial cell differentiation" NARROW [] synonym: "stimulation of endothelial cell differentiation" NARROW [] synonym: "up regulation of endothelial cell differentiation" EXACT [] synonym: "up-regulation of endothelial cell differentiation" EXACT [] synonym: "upregulation of endothelial cell differentiation" EXACT [] is_a: GO:0030858 ! positive regulation of epithelial cell differentiation is_a: GO:0045601 ! regulation of endothelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0045446 ! endothelial cell differentiation relationship: positively_regulates GO:0045446 ! endothelial cell differentiation [Term] id: GO:0045604 name: regulation of epidermal cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of epidermal cell differentiation." [GOC:go_curators] synonym: "regulation of hypodermal cell differentiation" RELATED [GOC:kmv, GOC:rk] is_a: GO:0030856 ! regulation of epithelial cell differentiation is_a: GO:0045682 ! regulation of epidermis development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0009913 ! epidermal cell differentiation relationship: regulates GO:0009913 ! epidermal cell differentiation [Term] id: GO:0045605 name: negative regulation of epidermal cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal cell differentiation." [GOC:go_curators] synonym: "down regulation of epidermal cell differentiation" EXACT [] synonym: "down-regulation of epidermal cell differentiation" EXACT [] synonym: "downregulation of epidermal cell differentiation" EXACT [] synonym: "inhibition of epidermal cell differentiation" NARROW [] synonym: "negative regulation of hypodermal cell differentiation" RELATED [GOC:kmv, GOC:rk] is_a: GO:0030857 ! negative regulation of epithelial cell differentiation is_a: GO:0045604 ! regulation of epidermal cell differentiation is_a: GO:0045683 ! negative regulation of epidermis development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0009913 ! epidermal cell differentiation relationship: negatively_regulates GO:0009913 ! epidermal cell differentiation [Term] id: GO:0045606 name: positive regulation of epidermal cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of epidermal cell differentiation." [GOC:go_curators] synonym: "activation of epidermal cell differentiation" NARROW [] synonym: "positive regulation of hypodermal cell differentiation" RELATED [GOC:kmv, GOC:rk] synonym: "stimulation of epidermal cell differentiation" NARROW [] synonym: "up regulation of epidermal cell differentiation" EXACT [] synonym: "up-regulation of epidermal cell differentiation" EXACT [] synonym: "upregulation of epidermal cell differentiation" EXACT [] is_a: GO:0030858 ! positive regulation of epithelial cell differentiation is_a: GO:0045604 ! regulation of epidermal cell differentiation is_a: GO:0045684 ! positive regulation of epidermis development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0009913 ! epidermal cell differentiation relationship: positively_regulates GO:0009913 ! epidermal cell differentiation [Term] id: GO:0045619 name: regulation of lymphocyte differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of lymphocyte differentiation." [GOC:go_curators] comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. synonym: "regulation of lymphocyte development" RELATED [GOC:add] is_a: GO:0051249 ! regulation of lymphocyte activation is_a: GO:1902105 ! regulation of leukocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030098 ! lymphocyte differentiation relationship: regulates GO:0030098 ! lymphocyte differentiation [Term] id: GO:0045620 name: negative regulation of lymphocyte differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte differentiation." [GOC:go_curators] comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. synonym: "down regulation of lymphocyte differentiation" EXACT [] synonym: "down-regulation of lymphocyte differentiation" EXACT [] synonym: "downregulation of lymphocyte differentiation" EXACT [] synonym: "inhibition of lymphocyte differentiation" NARROW [] synonym: "negative regulation of lymphocyte development" RELATED [GOC:add] is_a: GO:0045619 ! regulation of lymphocyte differentiation is_a: GO:0051250 ! negative regulation of lymphocyte activation is_a: GO:1902106 ! negative regulation of leukocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030098 ! lymphocyte differentiation relationship: negatively_regulates GO:0030098 ! lymphocyte differentiation [Term] id: GO:0045621 name: positive regulation of lymphocyte differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of lymphocyte differentiation." [GOC:go_curators] comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. synonym: "activation of lymphocyte differentiation" NARROW [] synonym: "positive regulation of lymphocyte development" RELATED [GOC:add] synonym: "stimulation of lymphocyte differentiation" NARROW [] synonym: "up regulation of lymphocyte differentiation" EXACT [] synonym: "up-regulation of lymphocyte differentiation" EXACT [] synonym: "upregulation of lymphocyte differentiation" EXACT [] is_a: GO:0045619 ! regulation of lymphocyte differentiation is_a: GO:0051251 ! positive regulation of lymphocyte activation is_a: GO:1902107 ! positive regulation of leukocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030098 ! lymphocyte differentiation relationship: positively_regulates GO:0030098 ! lymphocyte differentiation [Term] id: GO:0045637 name: regulation of myeloid cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of myeloid cell differentiation." [GOC:go_curators] is_a: GO:1903706 ! regulation of hemopoiesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030099 ! myeloid cell differentiation relationship: regulates GO:0030099 ! myeloid cell differentiation [Term] id: GO:0045638 name: negative regulation of myeloid cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation." [GOC:go_curators] synonym: "down regulation of myeloid cell differentiation" EXACT [] synonym: "down-regulation of myeloid cell differentiation" EXACT [] synonym: "downregulation of myeloid cell differentiation" EXACT [] synonym: "inhibition of myeloid cell differentiation" NARROW [] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0045637 ! regulation of myeloid cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030099 ! myeloid cell differentiation relationship: negatively_regulates GO:0030099 ! myeloid cell differentiation [Term] id: GO:0045639 name: positive regulation of myeloid cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of myeloid cell differentiation." [GOC:go_curators] synonym: "activation of myeloid cell differentiation" NARROW [] synonym: "stimulation of myeloid cell differentiation" NARROW [] synonym: "up regulation of myeloid cell differentiation" EXACT [] synonym: "up-regulation of myeloid cell differentiation" EXACT [] synonym: "upregulation of myeloid cell differentiation" EXACT [] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0045637 ! regulation of myeloid cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030099 ! myeloid cell differentiation relationship: positively_regulates GO:0030099 ! myeloid cell differentiation [Term] id: GO:0045646 name: regulation of erythrocyte differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of erythrocyte differentiation." [GOC:go_curators] synonym: "regulation of RBC differentiation" EXACT [CL:0000232] synonym: "regulation of red blood cell differentiation" EXACT [CL:0000232] is_a: GO:0045637 ! regulation of myeloid cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030218 ! erythrocyte differentiation relationship: regulates GO:0030218 ! erythrocyte differentiation [Term] id: GO:0045647 name: negative regulation of erythrocyte differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of erythrocyte differentiation." [GOC:go_curators] synonym: "down regulation of erythrocyte differentiation" EXACT [] synonym: "down-regulation of erythrocyte differentiation" EXACT [] synonym: "downregulation of erythrocyte differentiation" EXACT [] synonym: "inhibition of erythrocyte differentiation" NARROW [] synonym: "negative regulation of RBC differentiation" EXACT [CL:0000232] synonym: "negative regulation of red blood cell differentiation" EXACT [CL:0000232] is_a: GO:0045638 ! negative regulation of myeloid cell differentiation is_a: GO:0045646 ! regulation of erythrocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030218 ! erythrocyte differentiation relationship: negatively_regulates GO:0030218 ! erythrocyte differentiation [Term] id: GO:0045648 name: positive regulation of erythrocyte differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation." [GOC:go_curators] synonym: "activation of erythrocyte differentiation" NARROW [] synonym: "positive regulation of RBC differentiation" EXACT [CL:0000232] synonym: "positive regulation of red blood cell differentiation" EXACT [CL:0000232] synonym: "stimulation of erythrocyte differentiation" NARROW [] synonym: "up regulation of erythrocyte differentiation" EXACT [] synonym: "up-regulation of erythrocyte differentiation" EXACT [] synonym: "upregulation of erythrocyte differentiation" EXACT [] is_a: GO:0045639 ! positive regulation of myeloid cell differentiation is_a: GO:0045646 ! regulation of erythrocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030218 ! erythrocyte differentiation relationship: positively_regulates GO:0030218 ! erythrocyte differentiation [Term] id: GO:0045652 name: regulation of megakaryocyte differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of megakaryocyte differentiation." [GOC:go_curators] is_a: GO:0045637 ! regulation of myeloid cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030219 ! megakaryocyte differentiation relationship: regulates GO:0030219 ! megakaryocyte differentiation [Term] id: GO:0045653 name: negative regulation of megakaryocyte differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of megakaryocyte differentiation." [GOC:go_curators] synonym: "down regulation of megakaryocyte differentiation" EXACT [] synonym: "down-regulation of megakaryocyte differentiation" EXACT [] synonym: "downregulation of megakaryocyte differentiation" EXACT [] synonym: "inhibition of megakaryocyte differentiation" NARROW [] is_a: GO:0045638 ! negative regulation of myeloid cell differentiation is_a: GO:0045652 ! regulation of megakaryocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030219 ! megakaryocyte differentiation relationship: negatively_regulates GO:0030219 ! megakaryocyte differentiation [Term] id: GO:0045654 name: positive regulation of megakaryocyte differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of megakaryocyte differentiation." [GOC:go_curators] synonym: "activation of megakaryocyte differentiation" NARROW [] synonym: "stimulation of megakaryocyte differentiation" NARROW [] synonym: "up regulation of megakaryocyte differentiation" EXACT [] synonym: "up-regulation of megakaryocyte differentiation" EXACT [] synonym: "upregulation of megakaryocyte differentiation" EXACT [] is_a: GO:0045639 ! positive regulation of myeloid cell differentiation is_a: GO:0045652 ! regulation of megakaryocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030219 ! megakaryocyte differentiation relationship: positively_regulates GO:0030219 ! megakaryocyte differentiation [Term] id: GO:0045661 name: regulation of myoblast differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:go_curators, GOC:mtg_muscle] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0045445 ! myoblast differentiation relationship: regulates GO:0045445 ! myoblast differentiation [Term] id: GO:0045662 name: negative regulation of myoblast differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:go_curators, GOC:mtg_muscle] synonym: "down regulation of myoblast differentiation" EXACT [] synonym: "down-regulation of myoblast differentiation" EXACT [] synonym: "downregulation of myoblast differentiation" EXACT [] synonym: "inhibition of myoblast differentiation" NARROW [] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0045661 ! regulation of myoblast differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0045445 ! myoblast differentiation relationship: negatively_regulates GO:0045445 ! myoblast differentiation [Term] id: GO:0045663 name: positive regulation of myoblast differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:go_curators, GOC:mtg_muscle] synonym: "activation of myoblast differentiation" NARROW [] synonym: "stimulation of myoblast differentiation" NARROW [] synonym: "up regulation of myoblast differentiation" EXACT [] synonym: "up-regulation of myoblast differentiation" EXACT [] synonym: "upregulation of myoblast differentiation" EXACT [] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0045661 ! regulation of myoblast differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0045445 ! myoblast differentiation relationship: positively_regulates GO:0045445 ! myoblast differentiation [Term] id: GO:0045664 name: regulation of neuron differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of neuron differentiation." [GOC:go_curators] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030182 ! neuron differentiation relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa relationship: regulates GO:0030182 ! neuron differentiation [Term] id: GO:0045665 name: negative regulation of neuron differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation." [GOC:go_curators] synonym: "down regulation of neuron differentiation" EXACT [] synonym: "down-regulation of neuron differentiation" EXACT [] synonym: "downregulation of neuron differentiation" EXACT [] synonym: "inhibition of neuron differentiation" NARROW [] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0045664 ! regulation of neuron differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030182 ! neuron differentiation relationship: negatively_regulates GO:0030182 ! neuron differentiation [Term] id: GO:0045666 name: positive regulation of neuron differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of neuron differentiation." [GOC:go_curators] synonym: "activation of neuron differentiation" NARROW [] synonym: "stimulation of neuron differentiation" NARROW [] synonym: "up regulation of neuron differentiation" EXACT [] synonym: "up-regulation of neuron differentiation" EXACT [] synonym: "upregulation of neuron differentiation" EXACT [] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0045664 ! regulation of neuron differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030182 ! neuron differentiation relationship: positively_regulates GO:0030182 ! neuron differentiation [Term] id: GO:0045682 name: regulation of epidermis development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of epidermis development." [GOC:go_curators] synonym: "regulation of epidermal development" EXACT [] synonym: "regulation of hypodermis development" RELATED [GOC:kmv, GOC:rk] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0008544 ! epidermis development relationship: regulates GO:0008544 ! epidermis development [Term] id: GO:0045683 name: negative regulation of epidermis development namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of epidermis development." [GOC:go_curators] synonym: "down regulation of epidermis development" EXACT [] synonym: "down-regulation of epidermis development" EXACT [] synonym: "downregulation of epidermis development" EXACT [] synonym: "inhibition of epidermis development" NARROW [] synonym: "negative regulation of epidermal development" EXACT [] synonym: "negative regulation of hypodermis development" RELATED [GOC:kmv, GOC:rk] is_a: GO:0045682 ! regulation of epidermis development is_a: GO:0051093 ! negative regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0008544 ! epidermis development relationship: negatively_regulates GO:0008544 ! epidermis development [Term] id: GO:0045684 name: positive regulation of epidermis development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of epidermis development." [GOC:go_curators] synonym: "activation of epidermis development" NARROW [] synonym: "positive regulation of epidermal development" EXACT [] synonym: "positive regulation of hypodermis development" RELATED [GOC:kmv, GOC:rk] synonym: "stimulation of epidermis development" NARROW [] synonym: "up regulation of epidermis development" EXACT [] synonym: "up-regulation of epidermis development" EXACT [] synonym: "upregulation of epidermis development" EXACT [] is_a: GO:0045682 ! regulation of epidermis development is_a: GO:0051094 ! positive regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0008544 ! epidermis development relationship: positively_regulates GO:0008544 ! epidermis development [Term] id: GO:0045685 name: regulation of glial cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of glia cell differentiation." [GOC:go_curators] synonym: "regulation of glia cell differentiation" EXACT [] synonym: "regulation of neuroglia differentiation" EXACT [] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0010001 ! glial cell differentiation relationship: regulates GO:0010001 ! glial cell differentiation [Term] id: GO:0045686 name: negative regulation of glial cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of glia cell differentiation." [GOC:go_curators] synonym: "down regulation of glial cell differentiation" EXACT [] synonym: "down-regulation of glial cell differentiation" EXACT [] synonym: "downregulation of glial cell differentiation" EXACT [] synonym: "inhibition of glial cell differentiation" NARROW [] synonym: "negative regulation of glia cell differentiation" EXACT [] synonym: "negative regulation of neuroglia differentiation" EXACT [] is_a: GO:0014014 ! negative regulation of gliogenesis is_a: GO:0045685 ! regulation of glial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0010001 ! glial cell differentiation relationship: negatively_regulates GO:0010001 ! glial cell differentiation [Term] id: GO:0045687 name: positive regulation of glial cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of glia cell differentiation." [GOC:go_curators] synonym: "activation of glial cell differentiation" NARROW [] synonym: "positive regulation of glia cell differentiation" EXACT [] synonym: "positive regulation of neuroglia differentiation" EXACT [] synonym: "stimulation of glial cell differentiation" NARROW [] synonym: "up regulation of glial cell differentiation" EXACT [] synonym: "up-regulation of glial cell differentiation" EXACT [] synonym: "upregulation of glial cell differentiation" EXACT [] is_a: GO:0014015 ! positive regulation of gliogenesis is_a: GO:0045685 ! regulation of glial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0010001 ! glial cell differentiation relationship: positively_regulates GO:0010001 ! glial cell differentiation [Term] id: GO:0045700 name: regulation of spermatid nuclear differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of spermatid nuclear differentiation." [GOC:go_curators] is_a: GO:0051239 ! regulation of multicellular organismal process is_a: GO:1903353 ! regulation of nucleus organization is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007289 ! spermatid nucleus differentiation relationship: regulates GO:0007289 ! spermatid nucleus differentiation [Term] id: GO:0045701 name: negative regulation of spermatid nuclear differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of spermatid nuclear differentiation." [GOC:go_curators] synonym: "down regulation of spermatid nuclear differentiation" EXACT [] synonym: "down-regulation of spermatid nuclear differentiation" EXACT [] synonym: "downregulation of spermatid nuclear differentiation" EXACT [] synonym: "inhibition of spermatid nuclear differentiation" NARROW [] is_a: GO:0010639 ! negative regulation of organelle organization is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0045700 ! regulation of spermatid nuclear differentiation is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007289 ! spermatid nucleus differentiation relationship: negatively_regulates GO:0007289 ! spermatid nucleus differentiation [Term] id: GO:0045702 name: positive regulation of spermatid nuclear differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of spermatid nuclear differentiation." [GOC:go_curators] synonym: "activation of spermatid nuclear differentiation" NARROW [] synonym: "stimulation of spermatid nuclear differentiation" NARROW [] synonym: "up regulation of spermatid nuclear differentiation" EXACT [] synonym: "up-regulation of spermatid nuclear differentiation" EXACT [] synonym: "upregulation of spermatid nuclear differentiation" EXACT [] is_a: GO:0010638 ! positive regulation of organelle organization is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0045700 ! regulation of spermatid nuclear differentiation is_a: GO:2000243 ! positive regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007289 ! spermatid nucleus differentiation relationship: positively_regulates GO:0007289 ! spermatid nucleus differentiation [Term] id: GO:0045719 name: negative regulation of glycogen biosynthetic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen." [GOC:go_curators] synonym: "down regulation of glycogen biosynthetic process" EXACT [] synonym: "down-regulation of glycogen biosynthetic process" EXACT [] synonym: "downregulation of glycogen biosynthetic process" EXACT [] synonym: "inhibition of glycogen biosynthetic process" NARROW [] synonym: "negative regulation of glycogen anabolism" EXACT [] synonym: "negative regulation of glycogen biosynthesis" EXACT [] synonym: "negative regulation of glycogen formation" EXACT [] synonym: "negative regulation of glycogen synthesis" EXACT [] is_a: GO:0005979 ! regulation of glycogen biosynthetic process is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process is_a: GO:0070874 ! negative regulation of glycogen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0005978 ! glycogen biosynthetic process relationship: negatively_regulates GO:0005978 ! glycogen biosynthetic process [Term] id: GO:0045721 name: negative regulation of gluconeogenesis namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of gluconeogenesis." [GOC:go_curators] synonym: "down regulation of gluconeogenesis" EXACT [] synonym: "down-regulation of gluconeogenesis" EXACT [] synonym: "downregulation of gluconeogenesis" EXACT [] synonym: "inhibition of gluconeogenesis" NARROW [] is_a: GO:0006111 ! regulation of gluconeogenesis is_a: GO:0031327 ! negative regulation of cellular biosynthetic process is_a: GO:0045912 ! negative regulation of carbohydrate metabolic process is_a: GO:0062014 ! negative regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006094 ! gluconeogenesis relationship: negatively_regulates GO:0006094 ! gluconeogenesis [Term] id: GO:0045722 name: positive regulation of gluconeogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of gluconeogenesis." [GOC:go_curators] synonym: "activation of gluconeogenesis" NARROW [] synonym: "stimulation of gluconeogenesis" NARROW [] synonym: "up regulation of gluconeogenesis" EXACT [] synonym: "up-regulation of gluconeogenesis" EXACT [] synonym: "upregulation of gluconeogenesis" EXACT [] is_a: GO:0006111 ! regulation of gluconeogenesis is_a: GO:0010907 ! positive regulation of glucose metabolic process is_a: GO:0031328 ! positive regulation of cellular biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006094 ! gluconeogenesis relationship: positively_regulates GO:0006094 ! gluconeogenesis [Term] id: GO:0045724 name: positive regulation of cilium assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the formation of a cilium." [GOC:cilia, GOC:go_curators] synonym: "activation of cilium assembly" NARROW [] synonym: "positive regulation of flagellum assembly" BROAD [] synonym: "positive regulation of flagellum biogenesis" RELATED [GOC:mah] synonym: "stimulation of cilium assembly" NARROW [] synonym: "up regulation of cilium assembly" EXACT [] synonym: "up-regulation of cilium assembly" EXACT [] synonym: "upregulation of cilium assembly" EXACT [] is_a: GO:0120034 ! positive regulation of plasma membrane bounded cell projection assembly is_a: GO:1902017 ! regulation of cilium assembly is_a: GO:1902117 ! positive regulation of organelle assembly intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060271 ! cilium assembly relationship: positively_regulates GO:0060271 ! cilium assembly [Term] id: GO:0045725 name: positive regulation of glycogen biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen." [GOC:go_curators] synonym: "activation of glycogen biosynthetic process" NARROW [] synonym: "positive regulation of glycogen anabolism" EXACT [] synonym: "positive regulation of glycogen biosynthesis" EXACT [] synonym: "positive regulation of glycogen formation" EXACT [] synonym: "positive regulation of glycogen synthesis" EXACT [] synonym: "stimulation of glycogen biosynthetic process" NARROW [] synonym: "up regulation of glycogen biosynthetic process" EXACT [] synonym: "up-regulation of glycogen biosynthetic process" EXACT [] synonym: "upregulation of glycogen biosynthetic process" EXACT [] is_a: GO:0005979 ! regulation of glycogen biosynthetic process is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process is_a: GO:0070875 ! positive regulation of glycogen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0005978 ! glycogen biosynthetic process relationship: positively_regulates GO:0005978 ! glycogen biosynthetic process [Term] id: GO:0045727 name: positive regulation of translation namespace: biological_process alt_id: GO:0045946 def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "activation of protein biosynthetic process" NARROW [] synonym: "positive regulation of protein anabolism" EXACT [] synonym: "positive regulation of protein biosynthesis" EXACT [] synonym: "positive regulation of protein biosynthetic process" EXACT [GOC:tb] synonym: "positive regulation of protein formation" EXACT [] synonym: "positive regulation of protein synthesis" EXACT [] synonym: "stimulation of protein biosynthetic process" NARROW [] synonym: "up regulation of protein biosynthetic process" EXACT [] synonym: "up-regulation of protein biosynthetic process" EXACT [] synonym: "upregulation of protein biosynthetic process" EXACT [] is_a: GO:0006417 ! regulation of translation is_a: GO:0010628 ! positive regulation of gene expression is_a: GO:0034250 ! positive regulation of amide metabolic process is_a: GO:0051247 ! positive regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006412 ! translation relationship: positively_regulates GO:0006412 ! translation [Term] id: GO:0045732 name: positive regulation of protein catabolic process namespace: biological_process alt_id: GO:1903364 alt_id: GO:2000600 def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds." [GOC:go_curators] synonym: "activation of cellular protein breakdown" NARROW [GOC:TermGenie] synonym: "activation of cellular protein catabolic process" NARROW [GOC:TermGenie] synonym: "activation of cellular protein catabolism" NARROW [GOC:TermGenie] synonym: "activation of cellular protein degradation" NARROW [GOC:TermGenie] synonym: "activation of protein catabolic process" NARROW [] synonym: "positive regulation of cellular protein breakdown" EXACT [GOC:TermGenie] synonym: "positive regulation of cellular protein catabolic process" EXACT [] synonym: "positive regulation of cellular protein catabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of cellular protein degradation" EXACT [GOC:TermGenie] synonym: "positive regulation of cyclin breakdown" NARROW [GOC:obol] synonym: "positive regulation of cyclin catabolic process" NARROW [] synonym: "positive regulation of cyclin catabolism" NARROW [GOC:obol] synonym: "positive regulation of cyclin degradation" NARROW [GOC:obol] synonym: "positive regulation of degradation of cyclin" NARROW [GOC:obol] synonym: "positive regulation of protein breakdown" EXACT [] synonym: "positive regulation of protein catabolism" EXACT [] synonym: "positive regulation of protein degradation" EXACT [] synonym: "stimulation of protein catabolic process" NARROW [] synonym: "up regulation of cellular protein breakdown" EXACT [GOC:TermGenie] synonym: "up regulation of cellular protein catabolic process" EXACT [GOC:TermGenie] synonym: "up regulation of cellular protein catabolism" EXACT [GOC:TermGenie] synonym: "up regulation of cellular protein degradation" EXACT [GOC:TermGenie] synonym: "up regulation of protein catabolic process" EXACT [] synonym: "up-regulation of cellular protein breakdown" EXACT [GOC:TermGenie] synonym: "up-regulation of cellular protein catabolic process" EXACT [GOC:TermGenie] synonym: "up-regulation of cellular protein catabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of cellular protein degradation" EXACT [GOC:TermGenie] synonym: "up-regulation of protein catabolic process" EXACT [] synonym: "upregulation of cellular protein breakdown" EXACT [GOC:TermGenie] synonym: "upregulation of cellular protein catabolic process" EXACT [GOC:TermGenie] synonym: "upregulation of cellular protein catabolism" EXACT [GOC:TermGenie] synonym: "upregulation of cellular protein degradation" EXACT [GOC:TermGenie] synonym: "upregulation of protein catabolic process" EXACT [] is_a: GO:0009896 ! positive regulation of catabolic process is_a: GO:0042176 ! regulation of protein catabolic process is_a: GO:0051247 ! positive regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030163 ! protein catabolic process relationship: positively_regulates GO:0030163 ! protein catabolic process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23112" xsd:anyURI [Term] id: GO:0045733 name: acetate catabolic process namespace: biological_process alt_id: GO:0019663 def: "The chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid." [GOC:go_curators] synonym: "acetate breakdown" EXACT [] synonym: "acetate catabolism" EXACT [] synonym: "acetate degradation" EXACT [] synonym: "homoacetate catabolic process" RELATED [] is_a: GO:0006083 ! acetate metabolic process is_a: GO:0072329 ! monocarboxylic acid catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:30089 ! acetate relationship: has_primary_input CHEBI:30089 ! acetate [Term] id: GO:0045734 name: regulation of acetate catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid." [GOC:go_curators] synonym: "regulation of acetate breakdown" EXACT [] synonym: "regulation of acetate catabolism" EXACT [] synonym: "regulation of acetate degradation" EXACT [] is_a: GO:0010565 ! regulation of cellular ketone metabolic process is_a: GO:0031329 ! regulation of cellular catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0045733 ! acetate catabolic process relationship: regulates GO:0045733 ! acetate catabolic process [Term] id: GO:0045753 name: negative regulation of acetate catabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate." [GOC:go_curators] synonym: "down regulation of acetate catabolic process" EXACT [] synonym: "down-regulation of acetate catabolic process" EXACT [] synonym: "downregulation of acetate catabolic process" EXACT [] synonym: "inhibition of acetate catabolic process" NARROW [] synonym: "negative regulation of acetate breakdown" EXACT [] synonym: "negative regulation of acetate catabolism" EXACT [] synonym: "negative regulation of acetate degradation" EXACT [] is_a: GO:0031330 ! negative regulation of cellular catabolic process is_a: GO:0045734 ! regulation of acetate catabolic process is_a: GO:0062014 ! negative regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0045733 ! acetate catabolic process relationship: negatively_regulates GO:0045733 ! acetate catabolic process [Term] id: GO:0045754 name: positive regulation of acetate catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate." [GOC:go_curators] synonym: "activation of acetate catabolic process" NARROW [] synonym: "positive regulation of acetate breakdown" EXACT [] synonym: "positive regulation of acetate catabolism" EXACT [] synonym: "positive regulation of acetate degradation" EXACT [] synonym: "stimulation of acetate catabolic process" NARROW [] synonym: "up regulation of acetate catabolic process" EXACT [] synonym: "up-regulation of acetate catabolic process" EXACT [] synonym: "upregulation of acetate catabolic process" EXACT [] is_a: GO:0031331 ! positive regulation of cellular catabolic process is_a: GO:0045734 ! regulation of acetate catabolic process is_a: GO:0062013 ! positive regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0045733 ! acetate catabolic process relationship: positively_regulates GO:0045733 ! acetate catabolic process [Term] id: GO:0045759 name: negative regulation of action potential namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:go_curators] synonym: "down regulation of action potential" EXACT [] synonym: "down-regulation of action potential" EXACT [] synonym: "downregulation of action potential" EXACT [] synonym: "inhibition of action potential" NARROW [] is_a: GO:0048519 ! negative regulation of biological process is_a: GO:0098900 ! regulation of action potential intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001508 ! action potential relationship: negatively_regulates GO:0001508 ! action potential [Term] id: GO:0045760 name: positive regulation of action potential namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:go_curators] synonym: "activation of action potential" NARROW [] synonym: "stimulation of action potential" NARROW [] synonym: "up regulation of action potential" EXACT [] synonym: "up-regulation of action potential" EXACT [] synonym: "upregulation of action potential" EXACT [] is_a: GO:0048518 ! positive regulation of biological process is_a: GO:0098900 ! regulation of action potential intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001508 ! action potential relationship: positively_regulates GO:0001508 ! action potential [Term] id: GO:0045763 name: negative regulation of cellular amino acid metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amino acid." [GOC:go_curators] synonym: "down regulation of amino acid metabolic process" EXACT [] synonym: "down-regulation of amino acid metabolic process" EXACT [] synonym: "downregulation of amino acid metabolic process" EXACT [] synonym: "inhibition of amino acid metabolic process" NARROW [] synonym: "negative regulation of amino acid metabolism" EXACT [] is_a: GO:0006521 ! regulation of cellular amino acid metabolic process is_a: GO:0033239 ! negative regulation of amine metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006520 ! amino acid metabolic process relationship: negatively_regulates GO:0006520 ! amino acid metabolic process [Term] id: GO:0045764 name: positive regulation of amino acid metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amino acid." [GOC:go_curators] synonym: "activation of amino acid metabolic process" NARROW [] synonym: "positive regulation of amino acid metabolism" EXACT [] synonym: "positive regulation of cellular amino acid metabolic process" EXACT [] synonym: "stimulation of amino acid metabolic process" NARROW [] synonym: "up regulation of amino acid metabolic process" EXACT [] synonym: "up-regulation of amino acid metabolic process" EXACT [] synonym: "upregulation of amino acid metabolic process" EXACT [] is_a: GO:0006521 ! regulation of cellular amino acid metabolic process is_a: GO:0033240 ! positive regulation of amine metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006520 ! amino acid metabolic process relationship: positively_regulates GO:0006520 ! amino acid metabolic process [Term] id: GO:0045765 name: regulation of angiogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of angiogenesis." [GOC:go_curators] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis is_a: GO:1901342 ! regulation of vasculature development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001525 ! angiogenesis relationship: regulates GO:0001525 ! angiogenesis [Term] id: GO:0045766 name: positive regulation of angiogenesis namespace: biological_process def: "Any process that activates or increases angiogenesis." [GOC:go_curators] synonym: "activation of angiogenesis" NARROW [] synonym: "stimulation of angiogenesis" NARROW [] synonym: "up regulation of angiogenesis" EXACT [] synonym: "up-regulation of angiogenesis" EXACT [] synonym: "upregulation of angiogenesis" EXACT [] is_a: GO:0045765 ! regulation of angiogenesis is_a: GO:1904018 ! positive regulation of vasculature development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001525 ! angiogenesis relationship: positively_regulates GO:0001525 ! angiogenesis [Term] id: GO:0045769 name: negative regulation of asymmetric cell division namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of asymmetric cell division." [GOC:go_curators] synonym: "down regulation of asymmetric cell division" EXACT [] synonym: "down-regulation of asymmetric cell division" EXACT [] synonym: "downregulation of asymmetric cell division" EXACT [] synonym: "inhibition of asymmetric cell division" NARROW [] is_a: GO:0009786 ! regulation of asymmetric cell division is_a: GO:0051782 ! negative regulation of cell division intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0008356 ! asymmetric cell division relationship: negatively_regulates GO:0008356 ! asymmetric cell division [Term] id: GO:0045770 name: positive regulation of asymmetric cell division namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of asymmetric cell division." [GOC:go_curators] synonym: "activation of asymmetric cell division" NARROW [] synonym: "stimulation of asymmetric cell division" NARROW [] synonym: "up regulation of asymmetric cell division" EXACT [] synonym: "up-regulation of asymmetric cell division" EXACT [] synonym: "upregulation of asymmetric cell division" EXACT [] is_a: GO:0009786 ! regulation of asymmetric cell division is_a: GO:0051781 ! positive regulation of cell division intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0008356 ! asymmetric cell division relationship: positively_regulates GO:0008356 ! asymmetric cell division [Term] id: GO:0045778 name: positive regulation of ossification namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance." [GOC:go_curators] synonym: "activation of ossification" NARROW [] synonym: "positive regulation of bone biosynthesis" EXACT [] synonym: "positive regulation of bone formation" EXACT [] synonym: "stimulation of ossification" NARROW [] synonym: "up regulation of ossification" EXACT [] synonym: "up-regulation of ossification" EXACT [] synonym: "upregulation of ossification" EXACT [] is_a: GO:0030278 ! regulation of ossification is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001503 ! ossification relationship: positively_regulates GO:0001503 ! ossification [Term] id: GO:0045785 name: positive regulation of cell adhesion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell adhesion." [GOC:go_curators] synonym: "activation of cell adhesion" NARROW [] synonym: "stimulation of cell adhesion" NARROW [] synonym: "up regulation of cell adhesion" EXACT [] synonym: "up-regulation of cell adhesion" EXACT [] synonym: "upregulation of cell adhesion" EXACT [] is_a: GO:0030155 ! regulation of cell adhesion is_a: GO:0048522 ! positive regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007155 ! cell adhesion relationship: positively_regulates GO:0007155 ! cell adhesion [Term] id: GO:0045786 name: negative regulation of cell cycle namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "down regulation of progression through cell cycle" EXACT [] synonym: "down-regulation of progression through cell cycle" EXACT [] synonym: "downregulation of progression through cell cycle" EXACT [] synonym: "inhibition of progression through cell cycle" NARROW [] synonym: "negative regulation of cell cycle progression" EXACT [] synonym: "negative regulation of progression through cell cycle" EXACT [] is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:0051726 ! regulation of cell cycle intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007049 ! cell cycle relationship: negatively_regulates GO:0007049 ! cell cycle [Term] id: GO:0045787 name: positive regulation of cell cycle namespace: biological_process def: "Any process that activates or increases the rate or extent of progression through the cell cycle." [GOC:go_curators] synonym: "activation of progression through cell cycle" NARROW [] synonym: "positive regulation of cell cycle progression" EXACT [] synonym: "positive regulation of progression through cell cycle" EXACT [GOC:dph, GOC:tb] synonym: "stimulation of progression through cell cycle" NARROW [] synonym: "up regulation of progression through cell cycle" EXACT [] synonym: "up-regulation of progression through cell cycle" EXACT [] synonym: "upregulation of progression through cell cycle" EXACT [] is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:0051726 ! regulation of cell cycle intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007049 ! cell cycle relationship: positively_regulates GO:0007049 ! cell cycle [Term] id: GO:0045806 name: negative regulation of endocytosis namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of endocytosis." [GOC:go_curators] synonym: "down regulation of endocytosis" EXACT [] synonym: "down-regulation of endocytosis" EXACT [] synonym: "downregulation of endocytosis" EXACT [] synonym: "inhibition of endocytosis" NARROW [] is_a: GO:0030100 ! regulation of endocytosis is_a: GO:0051051 ! negative regulation of transport is_a: GO:0051129 ! negative regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006897 ! endocytosis relationship: negatively_regulates GO:0006897 ! endocytosis [Term] id: GO:0045807 name: positive regulation of endocytosis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of endocytosis." [GOC:go_curators] synonym: "activation of endocytosis" NARROW [] synonym: "stimulation of endocytosis" NARROW [] synonym: "up regulation of endocytosis" EXACT [] synonym: "up-regulation of endocytosis" EXACT [] synonym: "upregulation of endocytosis" EXACT [] is_a: GO:0030100 ! regulation of endocytosis is_a: GO:0051050 ! positive regulation of transport is_a: GO:0051130 ! positive regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006897 ! endocytosis relationship: positively_regulates GO:0006897 ! endocytosis [Term] id: GO:0045818 name: negative regulation of glycogen catabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen." [GOC:go_curators] synonym: "down regulation of glycogen catabolic process" EXACT [] synonym: "down-regulation of glycogen catabolic process" EXACT [] synonym: "downregulation of glycogen catabolic process" EXACT [] synonym: "inhibition of glycogen catabolic process" NARROW [] synonym: "negative regulation of glycogen breakdown" EXACT [] synonym: "negative regulation of glycogen catabolism" EXACT [] synonym: "negative regulation of glycogen degradation" EXACT [] synonym: "negative regulation of glycogenolysis" EXACT [GOC:sl] is_a: GO:0005981 ! regulation of glycogen catabolic process is_a: GO:0031330 ! negative regulation of cellular catabolic process is_a: GO:0070874 ! negative regulation of glycogen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0005980 ! glycogen catabolic process relationship: negatively_regulates GO:0005980 ! glycogen catabolic process [Term] id: GO:0045819 name: positive regulation of glycogen catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen." [GOC:go_curators] synonym: "activation of glycogen catabolic process" NARROW [] synonym: "positive regulation of glycogen breakdown" EXACT [] synonym: "positive regulation of glycogen catabolism" EXACT [] synonym: "positive regulation of glycogen degradation" EXACT [] synonym: "positive regulation of glycogenolysis" EXACT [GOC:sl] synonym: "stimulation of glycogen catabolic process" NARROW [] synonym: "up regulation of glycogen catabolic process" EXACT [] synonym: "up-regulation of glycogen catabolic process" EXACT [] synonym: "upregulation of glycogen catabolic process" EXACT [] is_a: GO:0005981 ! regulation of glycogen catabolic process is_a: GO:0031331 ! positive regulation of cellular catabolic process is_a: GO:0070875 ! positive regulation of glycogen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0005980 ! glycogen catabolic process relationship: positively_regulates GO:0005980 ! glycogen catabolic process [Term] id: GO:0045822 name: negative regulation of heart contraction namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction." [GOC:go_curators] synonym: "down regulation of heart contraction" EXACT [] synonym: "down-regulation of heart contraction" EXACT [] synonym: "downregulation of heart contraction" EXACT [] synonym: "inhibition of heart contraction" NARROW [] synonym: "negative regulation of cardiac contraction" RELATED [] is_a: GO:0008016 ! regulation of heart contraction is_a: GO:1903523 ! negative regulation of blood circulation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060047 ! heart contraction relationship: negatively_regulates GO:0060047 ! heart contraction [Term] id: GO:0045823 name: positive regulation of heart contraction namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of heart contraction." [GOC:go_curators] synonym: "activation of heart contraction" NARROW [] synonym: "positive regulation of cardiac contraction" EXACT [] synonym: "stimulation of heart contraction" NARROW [] synonym: "up regulation of heart contraction" EXACT [] synonym: "up-regulation of heart contraction" EXACT [] synonym: "upregulation of heart contraction" EXACT [] is_a: GO:0008016 ! regulation of heart contraction is_a: GO:1903524 ! positive regulation of blood circulation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060047 ! heart contraction relationship: positively_regulates GO:0060047 ! heart contraction [Term] id: GO:0045833 name: negative regulation of lipid metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipids." [GOC:go_curators] synonym: "down regulation of lipid metabolic process" EXACT [] synonym: "down-regulation of lipid metabolic process" EXACT [] synonym: "downregulation of lipid metabolic process" EXACT [] synonym: "inhibition of lipid metabolic process" NARROW [] synonym: "negative regulation of lipid metabolism" EXACT [] is_a: GO:0009892 ! negative regulation of metabolic process is_a: GO:0019216 ! regulation of lipid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006629 ! lipid metabolic process relationship: negatively_regulates GO:0006629 ! lipid metabolic process [Term] id: GO:0045834 name: positive regulation of lipid metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipids." [GOC:go_curators] synonym: "activation of lipid metabolic process" NARROW [] synonym: "positive regulation of lipid metabolism" EXACT [] synonym: "stimulation of lipid metabolic process" NARROW [] synonym: "up regulation of lipid metabolic process" EXACT [] synonym: "up-regulation of lipid metabolic process" EXACT [] synonym: "upregulation of lipid metabolic process" EXACT [] is_a: GO:0009893 ! positive regulation of metabolic process is_a: GO:0019216 ! regulation of lipid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006629 ! lipid metabolic process relationship: positively_regulates GO:0006629 ! lipid metabolic process [Term] id: GO:0045835 name: negative regulation of meiotic nuclear division namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis." [GOC:go_curators] synonym: "down regulation of meiosis" EXACT [] synonym: "down-regulation of meiosis" EXACT [] synonym: "downregulation of meiosis" EXACT [] synonym: "inhibition of meiosis" NARROW [] synonym: "negative regulation of meiosis" EXACT [] is_a: GO:0010948 ! negative regulation of cell cycle process is_a: GO:0040020 ! regulation of meiotic nuclear division is_a: GO:0051447 ! negative regulation of meiotic cell cycle is_a: GO:0051784 ! negative regulation of nuclear division intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0140013 ! meiotic nuclear division relationship: negatively_regulates GO:0140013 ! meiotic nuclear division [Term] id: GO:0045836 name: positive regulation of meiotic nuclear division namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of meiosis." [GOC:go_curators] synonym: "activation of meiosis" NARROW [] synonym: "positive regulation of meiosis" EXACT [] synonym: "stimulation of meiosis" NARROW [] synonym: "up regulation of meiosis" EXACT [] synonym: "up-regulation of meiosis" EXACT [] synonym: "upregulation of meiosis" EXACT [] is_a: GO:0040020 ! regulation of meiotic nuclear division is_a: GO:0051446 ! positive regulation of meiotic cell cycle is_a: GO:0051785 ! positive regulation of nuclear division is_a: GO:0090068 ! positive regulation of cell cycle process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0140013 ! meiotic nuclear division relationship: positively_regulates GO:0140013 ! meiotic nuclear division [Term] id: GO:0045839 name: negative regulation of mitotic nuclear division namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "down regulation of mitosis" EXACT [] synonym: "down-regulation of mitosis" EXACT [] synonym: "downregulation of mitosis" EXACT [] synonym: "inhibition of mitosis" NARROW [] synonym: "negative regulation of mitosis" EXACT [] is_a: GO:0007088 ! regulation of mitotic nuclear division is_a: GO:0010948 ! negative regulation of cell cycle process is_a: GO:0045930 ! negative regulation of mitotic cell cycle is_a: GO:0051784 ! negative regulation of nuclear division intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0140014 ! mitotic nuclear division relationship: negatively_regulates GO:0140014 ! mitotic nuclear division [Term] id: GO:0045840 name: positive regulation of mitotic nuclear division namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mitosis." [GOC:go_curators] synonym: "activation of mitosis" NARROW [] synonym: "mitogenic activity" NARROW [] synonym: "positive regulation of mitosis" EXACT [] synonym: "stimulation of mitosis" NARROW [] synonym: "up regulation of mitosis" EXACT [] synonym: "up-regulation of mitosis" EXACT [] synonym: "upregulation of mitosis" EXACT [] is_a: GO:0007088 ! regulation of mitotic nuclear division is_a: GO:0051785 ! positive regulation of nuclear division is_a: GO:0090068 ! positive regulation of cell cycle process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0140014 ! mitotic nuclear division relationship: positively_regulates GO:0140014 ! mitotic nuclear division [Term] id: GO:0045843 name: negative regulation of striated muscle tissue development namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle development." [GOC:go_curators] synonym: "down regulation of striated muscle development" EXACT [] synonym: "down-regulation of striated muscle development" EXACT [] synonym: "downregulation of striated muscle development" EXACT [] synonym: "inhibition of striated muscle development" NARROW [] is_a: GO:0016202 ! regulation of striated muscle tissue development is_a: GO:0048635 ! negative regulation of muscle organ development is_a: GO:1901862 ! negative regulation of muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0014706 ! striated muscle tissue development relationship: negatively_regulates GO:0014706 ! striated muscle tissue development [Term] id: GO:0045844 name: positive regulation of striated muscle tissue development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of striated muscle development." [GOC:go_curators] synonym: "activation of striated muscle development" NARROW [] synonym: "stimulation of striated muscle development" NARROW [] synonym: "up regulation of striated muscle development" EXACT [] synonym: "up-regulation of striated muscle development" EXACT [] synonym: "upregulation of striated muscle development" EXACT [] is_a: GO:0016202 ! regulation of striated muscle tissue development is_a: GO:0048636 ! positive regulation of muscle organ development is_a: GO:1901863 ! positive regulation of muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0014706 ! striated muscle tissue development relationship: positively_regulates GO:0014706 ! striated muscle tissue development [Term] id: GO:0045900 name: negative regulation of translational elongation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of translational elongation." [GOC:go_curators] synonym: "down regulation of translational elongation" EXACT [] synonym: "down-regulation of translational elongation" EXACT [] synonym: "downregulation of translational elongation" EXACT [] synonym: "inhibition of translational elongation" NARROW [] is_a: GO:0006448 ! regulation of translational elongation is_a: GO:0017148 ! negative regulation of translation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006414 ! translational elongation relationship: negatively_regulates GO:0006414 ! translational elongation [Term] id: GO:0045901 name: positive regulation of translational elongation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of translational elongation." [GOC:go_curators] synonym: "activation of translational elongation" NARROW [] synonym: "stimulation of translational elongation" NARROW [] synonym: "up regulation of translational elongation" EXACT [] synonym: "up-regulation of translational elongation" EXACT [] synonym: "upregulation of translational elongation" EXACT [] is_a: GO:0006448 ! regulation of translational elongation is_a: GO:0045727 ! positive regulation of translation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006414 ! translational elongation relationship: positively_regulates GO:0006414 ! translational elongation [Term] id: GO:0045904 name: negative regulation of translational termination namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of translational termination." [GOC:go_curators] synonym: "down regulation of translational termination" EXACT [] synonym: "down-regulation of translational termination" EXACT [] synonym: "downregulation of translational termination" EXACT [] synonym: "inhibition of translational termination" NARROW [] is_a: GO:0006449 ! regulation of translational termination is_a: GO:0017148 ! negative regulation of translation is_a: GO:0043242 ! negative regulation of protein-containing complex disassembly intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006415 ! translational termination relationship: negatively_regulates GO:0006415 ! translational termination [Term] id: GO:0045905 name: positive regulation of translational termination namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of translational termination." [GOC:go_curators] synonym: "activation of translational termination" NARROW [] synonym: "stimulation of translational termination" NARROW [] synonym: "up regulation of translational termination" EXACT [] synonym: "up-regulation of translational termination" EXACT [] synonym: "upregulation of translational termination" EXACT [] is_a: GO:0006449 ! regulation of translational termination is_a: GO:0043243 ! positive regulation of protein-containing complex disassembly is_a: GO:0045727 ! positive regulation of translation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006415 ! translational termination relationship: positively_regulates GO:0006415 ! translational termination [Term] id: GO:0045912 name: negative regulation of carbohydrate metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate." [GOC:go_curators] synonym: "down regulation of carbohydrate metabolic process" EXACT [] synonym: "down-regulation of carbohydrate metabolic process" EXACT [] synonym: "downregulation of carbohydrate metabolic process" EXACT [] synonym: "inhibition of carbohydrate metabolic process" NARROW [] synonym: "negative regulation of carbohydrate metabolism" EXACT [] is_a: GO:0006109 ! regulation of carbohydrate metabolic process is_a: GO:0009892 ! negative regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0005975 ! carbohydrate metabolic process relationship: negatively_regulates GO:0005975 ! carbohydrate metabolic process [Term] id: GO:0045913 name: positive regulation of carbohydrate metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate." [GOC:go_curators] synonym: "activation of carbohydrate metabolic process" NARROW [] synonym: "positive regulation of carbohydrate metabolism" EXACT [] synonym: "stimulation of carbohydrate metabolic process" NARROW [] synonym: "up regulation of carbohydrate metabolic process" EXACT [] synonym: "up-regulation of carbohydrate metabolic process" EXACT [] synonym: "upregulation of carbohydrate metabolic process" EXACT [] is_a: GO:0006109 ! regulation of carbohydrate metabolic process is_a: GO:0009893 ! positive regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0005975 ! carbohydrate metabolic process relationship: positively_regulates GO:0005975 ! carbohydrate metabolic process [Term] id: GO:0045914 name: negative regulation of catecholamine metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catecholamine." [GOC:go_curators] synonym: "down regulation of catecholamine metabolic process" EXACT [] synonym: "down-regulation of catecholamine metabolic process" EXACT [] synonym: "downregulation of catecholamine metabolic process" EXACT [] synonym: "inhibition of catecholamine metabolic process" NARROW [] synonym: "negative regulation of catecholamine metabolism" EXACT [] is_a: GO:0031324 ! negative regulation of cellular metabolic process is_a: GO:0033239 ! negative regulation of amine metabolic process is_a: GO:0042069 ! regulation of catecholamine metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006584 ! catecholamine metabolic process relationship: negatively_regulates GO:0006584 ! catecholamine metabolic process [Term] id: GO:0045915 name: positive regulation of catecholamine metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catecholamine." [GOC:go_curators] synonym: "activation of catecholamine metabolic process" NARROW [] synonym: "positive regulation of catecholamine metabolism" EXACT [] synonym: "stimulation of catecholamine metabolic process" NARROW [] synonym: "up regulation of catecholamine metabolic process" EXACT [] synonym: "up-regulation of catecholamine metabolic process" EXACT [] synonym: "upregulation of catecholamine metabolic process" EXACT [] is_a: GO:0031325 ! positive regulation of cellular metabolic process is_a: GO:0033240 ! positive regulation of amine metabolic process is_a: GO:0042069 ! regulation of catecholamine metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006584 ! catecholamine metabolic process relationship: positively_regulates GO:0006584 ! catecholamine metabolic process [Term] id: GO:0045920 name: negative regulation of exocytosis namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of exocytosis." [GOC:go_curators] synonym: "down regulation of exocytosis" EXACT [] synonym: "down-regulation of exocytosis" EXACT [] synonym: "downregulation of exocytosis" EXACT [] synonym: "inhibition of exocytosis" NARROW [] is_a: GO:0017157 ! regulation of exocytosis is_a: GO:1903531 ! negative regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006887 ! exocytosis relationship: negatively_regulates GO:0006887 ! exocytosis [Term] id: GO:0045921 name: positive regulation of exocytosis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of exocytosis." [GOC:go_curators] synonym: "activation of exocytosis" NARROW [] synonym: "stimulation of exocytosis" NARROW [] synonym: "up regulation of exocytosis" EXACT [] synonym: "up-regulation of exocytosis" EXACT [] synonym: "upregulation of exocytosis" EXACT [] is_a: GO:0017157 ! regulation of exocytosis is_a: GO:1903532 ! positive regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006887 ! exocytosis relationship: positively_regulates GO:0006887 ! exocytosis [Term] id: GO:0045926 name: negative regulation of growth namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism." [GOC:go_curators] synonym: "down regulation of growth" EXACT [] synonym: "down-regulation of growth" EXACT [] synonym: "downregulation of growth" EXACT [] synonym: "inhibition of growth" NARROW [] is_a: GO:0040008 ! regulation of growth is_a: GO:0048519 ! negative regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0040007 ! growth relationship: negatively_regulates GO:0040007 ! growth [Term] id: GO:0045927 name: positive regulation of growth namespace: biological_process def: "Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism." [GOC:go_curators] synonym: "activation of growth" NARROW [] synonym: "stimulation of growth" NARROW [] synonym: "up regulation of growth" EXACT [] synonym: "up-regulation of growth" EXACT [] synonym: "upregulation of growth" EXACT [] is_a: GO:0040008 ! regulation of growth is_a: GO:0048518 ! positive regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0040007 ! growth relationship: positively_regulates GO:0040007 ! growth [Term] id: GO:0045930 name: negative regulation of mitotic cell cycle namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of progression through the mitotic cell cycle." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "down regulation of progression through mitotic cell cycle" EXACT [] synonym: "down-regulation of progression through mitotic cell cycle" EXACT [] synonym: "downregulation of progression through mitotic cell cycle" EXACT [] synonym: "inhibition of progression through mitotic cell cycle" NARROW [] synonym: "negative regulation of mitotic cell cycle progression" EXACT [] synonym: "negative regulation of progression through mitotic cell cycle" EXACT [GOC:dph, GOC:tb] is_a: GO:0007346 ! regulation of mitotic cell cycle is_a: GO:0045786 ! negative regulation of cell cycle intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0000278 ! mitotic cell cycle relationship: negatively_regulates GO:0000278 ! mitotic cell cycle [Term] id: GO:0045931 name: positive regulation of mitotic cell cycle namespace: biological_process def: "Any process that activates or increases the rate or extent of progression through the mitotic cell cycle." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "activation of progression through mitotic cell cycle" NARROW [] synonym: "positive regulation of mitotic cell cycle progression" EXACT [] synonym: "positive regulation of progression through mitotic cell cycle" EXACT [GOC:dph, GOC:tb] synonym: "stimulation of progression through mitotic cell cycle" NARROW [] synonym: "up regulation of progression through mitotic cell cycle" EXACT [] synonym: "up-regulation of progression through mitotic cell cycle" EXACT [] synonym: "upregulation of progression through mitotic cell cycle" EXACT [] is_a: GO:0007346 ! regulation of mitotic cell cycle is_a: GO:0045787 ! positive regulation of cell cycle intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0000278 ! mitotic cell cycle relationship: positively_regulates GO:0000278 ! mitotic cell cycle [Term] id: GO:0045932 name: negative regulation of muscle contraction namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of muscle contraction." [GOC:go_curators] synonym: "down regulation of muscle contraction" EXACT [] synonym: "down-regulation of muscle contraction" EXACT [] synonym: "downregulation of muscle contraction" EXACT [] synonym: "inhibition of muscle contraction" NARROW [] is_a: GO:0006937 ! regulation of muscle contraction is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006936 ! muscle contraction relationship: negatively_regulates GO:0006936 ! muscle contraction [Term] id: GO:0045933 name: positive regulation of muscle contraction namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of muscle contraction." [GOC:go_curators] synonym: "activation of muscle contraction" NARROW [] synonym: "stimulation of muscle contraction" NARROW [] synonym: "up regulation of muscle contraction" EXACT [] synonym: "up-regulation of muscle contraction" EXACT [] synonym: "upregulation of muscle contraction" EXACT [] is_a: GO:0006937 ! regulation of muscle contraction is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006936 ! muscle contraction relationship: positively_regulates GO:0006936 ! muscle contraction [Term] id: GO:0045934 name: negative regulation of nucleobase-containing compound metabolic process namespace: biological_process def: "Any cellular process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:go_curators] synonym: "down regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT [] synonym: "down-regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT [] synonym: "downregulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT [] synonym: "inhibition of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" NARROW [] synonym: "negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" RELATED [GOC:dph, GOC:tb] synonym: "negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism" EXACT [] is_a: GO:0019219 ! regulation of nucleobase-containing compound metabolic process is_a: GO:0031324 ! negative regulation of cellular metabolic process is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006139 ! nucleobase-containing compound metabolic process relationship: negatively_regulates GO:0006139 ! nucleobase-containing compound metabolic process [Term] id: GO:0045935 name: positive regulation of nucleobase-containing compound metabolic process namespace: biological_process def: "Any cellular process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:go_curators] synonym: "activation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" NARROW [] synonym: "positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" RELATED [GOC:dph, GOC:tb] synonym: "positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism" EXACT [] synonym: "stimulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" NARROW [] synonym: "up regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT [] synonym: "up-regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT [] synonym: "upregulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT [] is_a: GO:0019219 ! regulation of nucleobase-containing compound metabolic process is_a: GO:0031325 ! positive regulation of cellular metabolic process is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006139 ! nucleobase-containing compound metabolic process relationship: positively_regulates GO:0006139 ! nucleobase-containing compound metabolic process [Term] id: GO:0045936 name: negative regulation of phosphate metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates." [GOC:go_curators] synonym: "down regulation of phosphate metabolic process" EXACT [] synonym: "down-regulation of phosphate metabolic process" EXACT [] synonym: "downregulation of phosphate metabolic process" EXACT [] synonym: "inhibition of phosphate metabolic process" NARROW [] synonym: "negative regulation of phosphate metabolism" EXACT [] is_a: GO:0010563 ! negative regulation of phosphorus metabolic process is_a: GO:0019220 ! regulation of phosphate metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006796 ! phosphate-containing compound metabolic process relationship: negatively_regulates GO:0006796 ! phosphate-containing compound metabolic process [Term] id: GO:0045937 name: positive regulation of phosphate metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates." [GOC:go_curators] synonym: "activation of phosphate metabolic process" NARROW [] synonym: "positive regulation of phosphate metabolism" EXACT [] synonym: "stimulation of phosphate metabolic process" NARROW [] synonym: "up regulation of phosphate metabolic process" EXACT [] synonym: "up-regulation of phosphate metabolic process" EXACT [] synonym: "upregulation of phosphate metabolic process" EXACT [] is_a: GO:0010562 ! positive regulation of phosphorus metabolic process is_a: GO:0019220 ! regulation of phosphate metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006796 ! phosphate-containing compound metabolic process relationship: positively_regulates GO:0006796 ! phosphate-containing compound metabolic process [Term] id: GO:0045939 name: negative regulation of steroid metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving steroids." [GOC:go_curators] synonym: "down regulation of steroid metabolic process" EXACT [] synonym: "down-regulation of steroid metabolic process" EXACT [] synonym: "downregulation of steroid metabolic process" EXACT [] synonym: "inhibition of steroid metabolic process" NARROW [] synonym: "negative regulation of steroid metabolism" EXACT [] is_a: GO:0019218 ! regulation of steroid metabolic process is_a: GO:0045833 ! negative regulation of lipid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0008202 ! steroid metabolic process relationship: negatively_regulates GO:0008202 ! steroid metabolic process [Term] id: GO:0045940 name: positive regulation of steroid metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving steroids." [GOC:go_curators] synonym: "activation of steroid metabolic process" NARROW [] synonym: "positive regulation of steroid metabolism" EXACT [] synonym: "stimulation of steroid metabolic process" NARROW [] synonym: "up regulation of steroid metabolic process" EXACT [] synonym: "up-regulation of steroid metabolic process" EXACT [] synonym: "upregulation of steroid metabolic process" EXACT [] is_a: GO:0019218 ! regulation of steroid metabolic process is_a: GO:0045834 ! positive regulation of lipid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0008202 ! steroid metabolic process relationship: positively_regulates GO:0008202 ! steroid metabolic process [Term] id: GO:0045947 name: negative regulation of translational initiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of translational initiation." [GOC:go_curators] synonym: "down regulation of translational initiation" EXACT [] synonym: "down-regulation of translational initiation" EXACT [] synonym: "downregulation of translational initiation" EXACT [] synonym: "inhibition of translational initiation" NARROW [] is_a: GO:0006446 ! regulation of translational initiation is_a: GO:0017148 ! negative regulation of translation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006413 ! translational initiation relationship: negatively_regulates GO:0006413 ! translational initiation [Term] id: GO:0045948 name: positive regulation of translational initiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of translational initiation." [GOC:go_curators] synonym: "activation of translational initiation" NARROW [] synonym: "stimulation of translational initiation" NARROW [] synonym: "up regulation of translational initiation" EXACT [] synonym: "up-regulation of translational initiation" EXACT [] synonym: "upregulation of translational initiation" EXACT [] is_a: GO:0006446 ! regulation of translational initiation is_a: GO:0045727 ! positive regulation of translation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006413 ! translational initiation relationship: positively_regulates GO:0006413 ! translational initiation [Term] id: GO:0045986 name: negative regulation of smooth muscle contraction namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle contraction." [GOC:go_curators] synonym: "down regulation of smooth muscle contraction" EXACT [] synonym: "down-regulation of smooth muscle contraction" EXACT [] synonym: "downregulation of smooth muscle contraction" EXACT [] synonym: "inhibition of smooth muscle contraction" NARROW [] synonym: "smooth muscle relaxation" RELATED [] is_a: GO:0006940 ! regulation of smooth muscle contraction is_a: GO:0045932 ! negative regulation of muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006939 ! smooth muscle contraction relationship: negatively_regulates GO:0006939 ! smooth muscle contraction [Term] id: GO:0045987 name: positive regulation of smooth muscle contraction namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of smooth muscle contraction." [GOC:go_curators] synonym: "activation of smooth muscle contraction" NARROW [] synonym: "stimulation of smooth muscle contraction" NARROW [] synonym: "up regulation of smooth muscle contraction" EXACT [] synonym: "up-regulation of smooth muscle contraction" EXACT [] synonym: "upregulation of smooth muscle contraction" EXACT [] is_a: GO:0006940 ! regulation of smooth muscle contraction is_a: GO:0045933 ! positive regulation of muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006939 ! smooth muscle contraction relationship: positively_regulates GO:0006939 ! smooth muscle contraction [Term] id: GO:0045988 name: negative regulation of striated muscle contraction namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle contraction." [GOC:go_curators] synonym: "down regulation of striated muscle contraction" EXACT [] synonym: "down-regulation of striated muscle contraction" EXACT [] synonym: "downregulation of striated muscle contraction" EXACT [] synonym: "inhibition of striated muscle contraction" NARROW [] is_a: GO:0006942 ! regulation of striated muscle contraction is_a: GO:0045932 ! negative regulation of muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006941 ! striated muscle contraction relationship: negatively_regulates GO:0006941 ! striated muscle contraction [Term] id: GO:0045989 name: positive regulation of striated muscle contraction namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of striated muscle contraction." [GOC:go_curators] synonym: "activation of striated muscle contraction" NARROW [] synonym: "stimulation of striated muscle contraction" NARROW [] synonym: "up regulation of striated muscle contraction" EXACT [] synonym: "up-regulation of striated muscle contraction" EXACT [] synonym: "upregulation of striated muscle contraction" EXACT [] is_a: GO:0006942 ! regulation of striated muscle contraction is_a: GO:0045933 ! positive regulation of muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006941 ! striated muscle contraction relationship: positively_regulates GO:0006941 ! striated muscle contraction [Term] id: GO:0045992 name: negative regulation of embryonic development namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of embryonic development." [GOC:go_curators] synonym: "down regulation of embryonic development" EXACT [] synonym: "down-regulation of embryonic development" EXACT [] synonym: "downregulation of embryonic development" EXACT [] synonym: "inhibition of embryonic development" NARROW [] is_a: GO:0045995 ! regulation of embryonic development is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0009790 ! embryo development relationship: negatively_regulates GO:0009790 ! embryo development [Term] id: GO:0045995 name: regulation of embryonic development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of embryonic development." [GOC:go_curators] is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0009790 ! embryo development relationship: regulates GO:0009790 ! embryo development [Term] id: GO:0046013 name: regulation of T cell homeostatic proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of resting T cell proliferation." [GOC:go_curators] synonym: "regulation of resting T cell proliferation" EXACT [] synonym: "regulation of T lymphocyte homeostatic proliferation" EXACT [] synonym: "regulation of T-cell homeostatic proliferation" EXACT [] synonym: "regulation of T-lymphocyte homeostatic proliferation" EXACT [] is_a: GO:0042129 ! regulation of T cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001777 ! T cell homeostatic proliferation relationship: regulates GO:0001777 ! T cell homeostatic proliferation [Term] id: GO:0046014 name: negative regulation of T cell homeostatic proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of resting T cell proliferation." [GOC:go_curators] synonym: "down regulation of T cell homeostatic proliferation" EXACT [] synonym: "down-regulation of T cell homeostatic proliferation" EXACT [] synonym: "downregulation of T cell homeostatic proliferation" EXACT [] synonym: "inhibition of T cell homeostatic proliferation" NARROW [] synonym: "negative regulation of resting T cell proliferation" EXACT [] synonym: "negative regulation of T lymphocyte homeostatic proliferation" EXACT [] synonym: "negative regulation of T-cell homeostatic proliferation" EXACT [] synonym: "negative regulation of T-lymphocyte homeostatic proliferation" EXACT [] is_a: GO:0042130 ! negative regulation of T cell proliferation is_a: GO:0046013 ! regulation of T cell homeostatic proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001777 ! T cell homeostatic proliferation relationship: negatively_regulates GO:0001777 ! T cell homeostatic proliferation [Term] id: GO:0046112 name: nucleobase biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid." [GOC:ai] synonym: "nucleobase anabolism" EXACT [] synonym: "nucleobase biosynthesis" EXACT [] synonym: "nucleobase formation" EXACT [] synonym: "nucleobase synthesis" EXACT [] is_a: GO:0009112 ! nucleobase metabolic process is_a: GO:0018130 ! heterocycle biosynthetic process is_a: GO:1901362 ! organic cyclic compound biosynthetic process is_a: GO:1901566 ! organonitrogen compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:18282 ! nucleobase relationship: has_primary_output CHEBI:18282 ! nucleobase [Term] id: GO:0046113 name: nucleobase catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid." [GOC:ai] synonym: "nucleobase breakdown" EXACT [] synonym: "nucleobase catabolism" EXACT [] synonym: "nucleobase degradation" EXACT [] is_a: GO:0009112 ! nucleobase metabolic process is_a: GO:0046700 ! heterocycle catabolic process is_a: GO:1901361 ! organic cyclic compound catabolic process is_a: GO:1901565 ! organonitrogen compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:18282 ! nucleobase relationship: has_primary_input CHEBI:18282 ! nucleobase [Term] id: GO:0046189 name: phenol-containing compound biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring." [GOC:ai] synonym: "phenol-containing compound anabolism" EXACT [] synonym: "phenol-containing compound biosynthesis" EXACT [] synonym: "phenol-containing compound formation" EXACT [] synonym: "phenol-containing compound synthesis" EXACT [] is_a: GO:0018958 ! phenol-containing compound metabolic process is_a: GO:0019438 ! aromatic compound biosynthetic process is_a: GO:1901362 ! organic cyclic compound biosynthetic process is_a: GO:1901617 ! organic hydroxy compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:33853 ! phenols relationship: has_primary_output CHEBI:33853 ! phenols [Term] id: GO:0046219 name: indolalkylamine biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group." [GOC:curators] synonym: "indolalkylamine anabolism" EXACT [] synonym: "indolalkylamine biosynthesis" EXACT [] synonym: "indolalkylamine formation" EXACT [] synonym: "indolalkylamine synthesis" EXACT [] is_a: GO:0006586 ! indolalkylamine metabolic process is_a: GO:0042401 ! biogenic amine biosynthetic process is_a: GO:0042435 ! indole-containing compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:38631 ! aminoalkylindole relationship: has_primary_output CHEBI:38631 ! aminoalkylindole [Term] id: GO:0046348 name: amino sugar catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of any amino sugar, sugars containing an amino group in place of a hydroxyl group." [GOC:curators] synonym: "amino sugar breakdown" EXACT [] synonym: "amino sugar catabolism" EXACT [] synonym: "amino sugar degradation" EXACT [] synonym: "aminosaccharide catabolic process" EXACT [] synonym: "aminosaccharide catabolism" EXACT [] is_a: GO:0006040 ! amino sugar metabolic process is_a: GO:1901136 ! carbohydrate derivative catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:28963 ! amino sugar relationship: has_primary_input CHEBI:28963 ! amino sugar [Term] id: GO:0046349 name: amino sugar biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of any amino sugar, sugars containing an amino group in place of a hydroxyl group." [GOC:curators] synonym: "amino sugar anabolism" EXACT [] synonym: "amino sugar biosynthesis" EXACT [] synonym: "amino sugar formation" EXACT [] synonym: "amino sugar synthesis" EXACT [] synonym: "aminosaccharide biosynthesis" EXACT [] synonym: "aminosaccharide biosynthetic process" EXACT [] is_a: GO:0006040 ! amino sugar metabolic process is_a: GO:1901137 ! carbohydrate derivative biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:28963 ! amino sugar relationship: has_primary_output CHEBI:28963 ! amino sugar [Term] id: GO:0046364 name: monosaccharide biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms." [ISBN:0198506732] synonym: "monosaccharide anabolism" EXACT [] synonym: "monosaccharide biosynthesis" EXACT [] synonym: "monosaccharide formation" EXACT [] synonym: "monosaccharide synthesis" EXACT [] is_a: GO:0005996 ! monosaccharide metabolic process is_a: GO:0016051 ! carbohydrate biosynthetic process is_a: GO:0044283 ! small molecule biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:35381 ! monosaccharide relationship: has_primary_output CHEBI:35381 ! monosaccharide [Term] id: GO:0046365 name: monosaccharide catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms." [ISBN:0198506732] synonym: "monosaccharide breakdown" EXACT [] synonym: "monosaccharide catabolism" EXACT [] synonym: "monosaccharide degradation" EXACT [] is_a: GO:0005996 ! monosaccharide metabolic process is_a: GO:0016052 ! carbohydrate catabolic process is_a: GO:0044282 ! small molecule catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:35381 ! monosaccharide relationship: has_primary_input CHEBI:35381 ! monosaccharide [Term] id: GO:0046394 name: carboxylic acid biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups." [ISBN:0198506732] synonym: "carboxylic acid anabolism" EXACT [] synonym: "carboxylic acid biosynthesis" EXACT [] synonym: "carboxylic acid formation" EXACT [] synonym: "carboxylic acid synthesis" EXACT [] is_a: GO:0016053 ! organic acid biosynthetic process is_a: GO:0019752 ! carboxylic acid metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:29067 ! carboxylic acid anion relationship: has_primary_output CHEBI:29067 ! carboxylic acid anion [Term] id: GO:0046395 name: carboxylic acid catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups." [ISBN:0198506732] synonym: "carboxylic acid breakdown" EXACT [] synonym: "carboxylic acid catabolism" EXACT [] synonym: "carboxylic acid degradation" EXACT [] is_a: GO:0016054 ! organic acid catabolic process is_a: GO:0019752 ! carboxylic acid metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:29067 ! carboxylic acid anion relationship: has_primary_input CHEBI:29067 ! carboxylic acid anion [Term] id: GO:0046483 name: heterocycle metabolic process namespace: biological_process def: "The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings)." [ISBN:0198506732] subset: goslim_pir synonym: "heterocycle metabolism" EXACT [] is_a: GO:0044237 ! cellular metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:5686 ! heterocyclic compound relationship: has_primary_input_or_output CHEBI:5686 ! heterocyclic compound [Term] id: GO:0046530 name: photoreceptor cell differentiation namespace: biological_process alt_id: GO:0007467 def: "The specialization of organization of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light. An example of this process is found in Drosophila melanogaster." [GOC:ai, ISBN:0198506732] is_a: GO:0030182 ! neuron differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000210 ! photoreceptor cell relationship: results_in_acquisition_of_features_of CL:0000210 ! photoreceptor cell [Term] id: GO:0046532 name: regulation of photoreceptor cell differentiation namespace: biological_process alt_id: GO:0045673 def: "Any process that modulates the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster." [GOC:go_curators] synonym: "regulation of photoreceptor differentiation" EXACT [] is_a: GO:0045664 ! regulation of neuron differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0046530 ! photoreceptor cell differentiation relationship: regulates GO:0046530 ! photoreceptor cell differentiation [Term] id: GO:0046533 name: negative regulation of photoreceptor cell differentiation namespace: biological_process alt_id: GO:0045674 def: "Any process that stops, prevents, or reduces the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster." [GOC:go_curators] synonym: "down regulation of photoreceptor cell differentiation" EXACT [] synonym: "down regulation of photoreceptor differentiation" EXACT [] synonym: "down-regulation of photoreceptor cell differentiation" EXACT [] synonym: "down-regulation of photoreceptor differentiation" EXACT [] synonym: "downregulation of photoreceptor cell differentiation" EXACT [] synonym: "downregulation of photoreceptor differentiation" EXACT [] synonym: "inhibition of photoreceptor cell differentiation" NARROW [] synonym: "inhibition of photoreceptor differentiation" NARROW [] synonym: "negative regulation of photoreceptor differentiation" EXACT [] is_a: GO:0045665 ! negative regulation of neuron differentiation is_a: GO:0046532 ! regulation of photoreceptor cell differentiation is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0046530 ! photoreceptor cell differentiation relationship: negatively_regulates GO:0046530 ! photoreceptor cell differentiation [Term] id: GO:0046534 name: positive regulation of photoreceptor cell differentiation namespace: biological_process alt_id: GO:0045675 def: "Any process that activates or increases the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster." [GOC:go_curators] synonym: "activation of photoreceptor cell differentiation" NARROW [] synonym: "activation of photoreceptor differentiation" NARROW [] synonym: "positive regulation of photoreceptor differentiation" EXACT [] synonym: "stimulation of photoreceptor cell differentiation" NARROW [] synonym: "stimulation of photoreceptor differentiation" NARROW [] synonym: "up regulation of photoreceptor cell differentiation" EXACT [] synonym: "up regulation of photoreceptor differentiation" EXACT [] synonym: "up-regulation of photoreceptor cell differentiation" EXACT [] synonym: "up-regulation of photoreceptor differentiation" EXACT [] synonym: "upregulation of photoreceptor cell differentiation" EXACT [] synonym: "upregulation of photoreceptor differentiation" EXACT [] is_a: GO:0045666 ! positive regulation of neuron differentiation is_a: GO:0046532 ! regulation of photoreceptor cell differentiation is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0046530 ! photoreceptor cell differentiation relationship: positively_regulates GO:0046530 ! photoreceptor cell differentiation [Term] id: GO:0046545 name: development of primary female sexual characteristics namespace: biological_process def: "The process whose specific outcome is the progression of the primary female sexual characteristics over time, from their formation to the mature structure. The primary female sexual characteristics are the ovaries, and they develop in response to sex hormone secretion." [GOC:ai] is_a: GO:0045137 ! development of primary sexual characteristics relationship: part_of GO:0046660 ! female sex differentiation [Term] id: GO:0046546 name: development of primary male sexual characteristics namespace: biological_process def: "The process whose specific outcome is the progression of the primary male sexual characteristics over time, from their formation to the mature structures. The primary male sexual characteristics are the testes, and they develop in response to sex hormone secretion." [GOC:ai] is_a: GO:0045137 ! development of primary sexual characteristics relationship: part_of GO:0046661 ! male sex differentiation [Term] id: GO:0046548 name: retinal rod cell development namespace: biological_process def: "Development of a rod cell, one of the sensory cells in the eye that reacts to the presence of light. Rod cells contain the photopigment rhodopsin or porphyropsin and are responsible for vision in dim light." [ISBN:0198506732] is_a: GO:0042462 ! eye photoreceptor cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000604 ! retinal rod cell relationship: part_of GO:0060221 ! retinal rod cell differentiation relationship: results_in_development_of CL:0000604 ! retinal rod cell [Term] id: GO:0046549 name: retinal cone cell development namespace: biological_process def: "Development of a cone cell, one of the sensory cells in the eye that reacts to the presence of light. Cone cells contain the photopigment iodopsin or cyanopsin and are responsible for photopic (daylight) vision." [ISBN:0198506732] is_a: GO:0042462 ! eye photoreceptor cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000573 ! retinal cone cell relationship: part_of GO:0042670 ! retinal cone cell differentiation relationship: results_in_development_of CL:0000573 ! retinal cone cell [Term] id: GO:0046620 name: regulation of organ growth namespace: biological_process def: "Any process that modulates the frequency, rate or extent of growth of an organ of an organism." [GOC:bf, GOC:tb] is_a: GO:0048638 ! regulation of developmental growth is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0035265 ! organ growth relationship: regulates GO:0035265 ! organ growth [Term] id: GO:0046621 name: negative regulation of organ growth namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism." [GOC:bf, GOC:tb] is_a: GO:0046620 ! regulation of organ growth is_a: GO:0048640 ! negative regulation of developmental growth is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0035265 ! organ growth relationship: negatively_regulates GO:0035265 ! organ growth [Term] id: GO:0046622 name: positive regulation of organ growth namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of growth of an organ of an organism." [GOC:bf, GOC:tb] is_a: GO:0046620 ! regulation of organ growth is_a: GO:0048639 ! positive regulation of developmental growth is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0035265 ! organ growth relationship: positively_regulates GO:0035265 ! organ growth [Term] id: GO:0046649 name: lymphocyte activation namespace: biological_process def: "A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor." [GOC:mgi_curators, ISBN:0781735149] is_a: GO:0045321 ! leukocyte activation intersection_of: GO:0001775 ! cell activation intersection_of: has_primary_input CL:0000542 ! lymphocyte relationship: has_primary_input CL:0000542 ! lymphocyte [Term] id: GO:0046651 name: lymphocyte proliferation namespace: biological_process def: "The expansion of a lymphocyte population by cell division." [GOC:ai] is_a: GO:0032943 ! mononuclear cell proliferation is_a: GO:0046649 ! lymphocyte activation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000542 ! lymphocyte relationship: acts_on_population_of CL:0000542 ! lymphocyte [Term] id: GO:0046660 name: female sex differentiation namespace: biological_process def: "The establishment of the sex of a female organism by physical differentiation." [GOC:bf] is_a: GO:0007548 ! sex differentiation relationship: part_of GO:0007275 ! multicellular organism development [Term] id: GO:0046661 name: male sex differentiation namespace: biological_process def: "The establishment of the sex of a male organism by physical differentiation." [GOC:bf] is_a: GO:0007548 ! sex differentiation relationship: part_of GO:0007275 ! multicellular organism development [Term] id: GO:0046666 name: retinal cell programmed cell death namespace: biological_process def: "Programmed cell death that occurs in the developing retina." [GOC:bf] synonym: "programmed cell death, retina cells" EXACT [] synonym: "programmed cell death, retinal cells" EXACT [] synonym: "retina cell programmed cell death" EXACT [] synonym: "retina programmed cell death" EXACT [] synonym: "retinal programmed cell death" EXACT [] is_a: GO:0010623 ! programmed cell death involved in cell development relationship: part_of GO:0048592 ! eye morphogenesis [Term] id: GO:0046667 name: compound eye retinal cell programmed cell death namespace: biological_process def: "Programmed cell death that occurs in the retina to remove excess cells between ommatidia, thus resulting in a hexagonal lattice, precise with respect to cell number and position surrounding each ommatidium." [PMID:12006672] is_a: GO:0046666 ! retinal cell programmed cell death intersection_of: GO:0046666 ! retinal cell programmed cell death intersection_of: results_in_maturation_of UBERON:0000018 ! compound eye relationship: part_of GO:0001745 ! compound eye morphogenesis relationship: results_in_maturation_of UBERON:0000018 ! compound eye [Term] id: GO:0046668 name: regulation of retinal cell programmed cell death namespace: biological_process def: "Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the retina." [GOC:ai, GOC:tb] synonym: "regulation of retinal programmed cell death" EXACT [GOC:tb] is_a: GO:0043067 ! regulation of programmed cell death is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0046666 ! retinal cell programmed cell death relationship: regulates GO:0046666 ! retinal cell programmed cell death [Term] id: GO:0046669 name: regulation of compound eye retinal cell programmed cell death namespace: biological_process def: "Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the compound eye retina." [GOC:ai] synonym: "regulation of retinal cell programmed cell death" BROAD [] is_a: GO:0046668 ! regulation of retinal cell programmed cell death intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0046667 ! compound eye retinal cell programmed cell death relationship: regulates GO:0046667 ! compound eye retinal cell programmed cell death [Term] id: GO:0046670 name: positive regulation of retinal cell programmed cell death namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the retina." [GOC:ai, GOC:tb] synonym: "activation of retinal programmed cell death" NARROW [] synonym: "positive regulation of retinal programmed cell death" EXACT [GOC:tb] synonym: "stimulation of retinal programmed cell death" NARROW [] synonym: "up regulation of retinal programmed cell death" EXACT [] synonym: "up-regulation of retinal programmed cell death" EXACT [] synonym: "upregulation of retinal programmed cell death" EXACT [] is_a: GO:0043068 ! positive regulation of programmed cell death is_a: GO:0046668 ! regulation of retinal cell programmed cell death is_a: GO:0051094 ! positive regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0046666 ! retinal cell programmed cell death relationship: positively_regulates GO:0046666 ! retinal cell programmed cell death [Term] id: GO:0046671 name: negative regulation of retinal cell programmed cell death namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the retina." [GOC:ai, GOC:tb] synonym: "down regulation of retinal programmed cell death" EXACT [] synonym: "down-regulation of retinal programmed cell death" EXACT [] synonym: "downregulation of retinal programmed cell death" EXACT [] synonym: "inhibition of retinal programmed cell death" NARROW [] synonym: "negative regulation of retinal programmed cell death" EXACT [GOC:tb] is_a: GO:0043069 ! negative regulation of programmed cell death is_a: GO:0046668 ! regulation of retinal cell programmed cell death is_a: GO:0051093 ! negative regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0046666 ! retinal cell programmed cell death relationship: negatively_regulates GO:0046666 ! retinal cell programmed cell death [Term] id: GO:0046672 name: positive regulation of compound eye retinal cell programmed cell death namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the compound eye retina." [GOC:ai] synonym: "activation of retinal cell programmed cell death" BROAD [] synonym: "positive regulation of retinal cell programmed cell death" BROAD [] synonym: "stimulation of retinal cell programmed cell death" BROAD [] synonym: "up regulation of retinal cell programmed cell death" BROAD [] synonym: "up-regulation of retinal cell programmed cell death" BROAD [] synonym: "upregulation of retinal cell programmed cell death" BROAD [] is_a: GO:0046669 ! regulation of compound eye retinal cell programmed cell death is_a: GO:0046670 ! positive regulation of retinal cell programmed cell death intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0046667 ! compound eye retinal cell programmed cell death relationship: positively_regulates GO:0046667 ! compound eye retinal cell programmed cell death [Term] id: GO:0046673 name: negative regulation of compound eye retinal cell programmed cell death namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the compound eye retina." [GOC:ai] synonym: "down regulation of retinal cell programmed cell death" BROAD [] synonym: "down-regulation of retinal cell programmed cell death" BROAD [] synonym: "downregulation of retinal cell programmed cell death" BROAD [] synonym: "inhibition of retinal cell programmed cell death" BROAD [] synonym: "negative regulation of retina cell programmed cell death" BROAD [] synonym: "negative regulation of retinal cell programmed cell death" BROAD [] is_a: GO:0046669 ! regulation of compound eye retinal cell programmed cell death is_a: GO:0046671 ! negative regulation of retinal cell programmed cell death intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0046667 ! compound eye retinal cell programmed cell death relationship: negatively_regulates GO:0046667 ! compound eye retinal cell programmed cell death [Term] id: GO:0046676 name: negative regulation of insulin secretion namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of insulin." [GOC:ai] synonym: "down regulation of insulin secretion" EXACT [] synonym: "down-regulation of insulin secretion" EXACT [] synonym: "downregulation of insulin secretion" EXACT [] synonym: "inhibition of insulin secretion" NARROW [] is_a: GO:0050709 ! negative regulation of protein secretion is_a: GO:0050796 ! regulation of insulin secretion is_a: GO:0090278 ! negative regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030073 ! insulin secretion relationship: negatively_regulates GO:0030073 ! insulin secretion [Term] id: GO:0046681 name: response to carbamate namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbamate stimulus. Carbamates are a group of insecticides and parasiticides that act by inhibiting cholinesterase." [ISBN:0721662544] synonym: "carbamate resistance" RELATED [] synonym: "carbamate susceptibility/resistance" RELATED [] is_a: GO:0010243 ! response to organonitrogen compound is_a: GO:0017085 ! response to insecticide is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus intersection_of: has_primary_input CHEBI:13941 ! carbamate relationship: has_primary_input CHEBI:13941 ! carbamate [Term] id: GO:0046700 name: heterocycle catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings)." [GOC:ai] synonym: "heterocycle breakdown" EXACT [] synonym: "heterocycle catabolism" EXACT [] synonym: "heterocycle degradation" EXACT [] is_a: GO:0044248 ! cellular catabolic process is_a: GO:0046483 ! heterocycle metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:5686 ! heterocyclic compound relationship: has_primary_input CHEBI:5686 ! heterocyclic compound [Term] id: GO:0046716 name: muscle cell cellular homeostasis namespace: biological_process def: "The cellular homeostatic process that preserves a muscle cell in a stable functional or structural state." [GOC:mah, PMID:3091429, PMID:7781901] synonym: "muscle fiber maintenance" NARROW [GOC:dph, GOC:tb] synonym: "muscle homeostasis" RELATED [GOC:dph] is_a: GO:0019725 ! cellular homeostasis intersection_of: GO:0019725 ! cellular homeostasis intersection_of: occurs_in CL:0000187 ! muscle cell relationship: occurs_in CL:0000187 ! muscle cell property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24218" xsd:anyURI property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0046717 name: acid secretion namespace: biological_process def: "The controlled release of acid by a cell or a tissue." [GOC:ai] is_a: GO:0046903 ! secretion [Term] id: GO:0046785 name: microtubule polymerization namespace: biological_process def: "The addition of tubulin heterodimers to one or both ends of a microtubule." [GOC:ai, GOC:go_curators] synonym: "microtubule assembly" EXACT [] synonym: "microtubule formation" RELATED [] is_a: GO:0031109 ! microtubule polymerization or depolymerization is_a: GO:0051258 ! protein polymerization is_a: GO:0097435 ! supramolecular fiber organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0005874 ! microtubule relationship: results_in_assembly_of GO:0005874 ! microtubule relationship: starts_with GO:0007020 ! microtubule nucleation [Term] id: GO:0046873 name: metal ion transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of metal ions from one side of a membrane to the other." [GOC:ai] synonym: "heavy metal ion porter activity" NARROW [] synonym: "heavy metal ion transporter activity" NARROW [] synonym: "heavy metal ion:hydrogen symporter activity" NARROW [] synonym: "heavy metal-exporting ATPase activity" NARROW [] synonym: "high affinity metal ion uptake transporter activity" NARROW [] synonym: "low affinity metal ion uptake transporter activity" NARROW [] is_a: GO:0008324 ! monoatomic cation transmembrane transporter activity is_a: GO:0022890 ! inorganic cation transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:25213 ! metal cation relationship: has_primary_input CHEBI:25213 ! metal cation relationship: part_of GO:0030001 ! metal ion transport [Term] id: GO:0046879 name: hormone secretion namespace: biological_process def: "The regulated release of hormones, substances with a specific regulatory effect on a particular organ or group of cells." [ISBN:0198506732] is_a: GO:0009914 ! hormone transport is_a: GO:0023061 ! signal release [Term] id: GO:0046883 name: regulation of hormone secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of a hormone from a cell." [GOC:ai] is_a: GO:0010646 ! regulation of cell communication is_a: GO:0010817 ! regulation of hormone levels is_a: GO:0023051 ! regulation of signaling is_a: GO:1903530 ! regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0046879 ! hormone secretion relationship: regulates GO:0046879 ! hormone secretion [Term] id: GO:0046887 name: positive regulation of hormone secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of a hormone from a cell." [GOC:ai] synonym: "activation of hormone secretion" NARROW [] synonym: "stimulation of hormone secretion" NARROW [] synonym: "up regulation of hormone secretion" EXACT [] synonym: "up-regulation of hormone secretion" EXACT [] synonym: "upregulation of hormone secretion" EXACT [] is_a: GO:0010647 ! positive regulation of cell communication is_a: GO:0023056 ! positive regulation of signaling is_a: GO:0046883 ! regulation of hormone secretion is_a: GO:1903532 ! positive regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0046879 ! hormone secretion relationship: positively_regulates GO:0046879 ! hormone secretion [Term] id: GO:0046888 name: negative regulation of hormone secretion namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a hormone from a cell." [GOC:ai] synonym: "down regulation of hormone secretion" EXACT [] synonym: "down-regulation of hormone secretion" EXACT [] synonym: "downregulation of hormone secretion" EXACT [] synonym: "inhibition of hormone secretion" NARROW [] is_a: GO:0010648 ! negative regulation of cell communication is_a: GO:0023057 ! negative regulation of signaling is_a: GO:0046883 ! regulation of hormone secretion is_a: GO:1903531 ! negative regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0046879 ! hormone secretion relationship: negatively_regulates GO:0046879 ! hormone secretion [Term] id: GO:0046889 name: positive regulation of lipid biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids." [GOC:ai] synonym: "activation of lipid biosynthetic process" NARROW [] synonym: "positive regulation of lipid anabolism" EXACT [] synonym: "positive regulation of lipid biosynthesis" EXACT [] synonym: "positive regulation of lipid formation" EXACT [] synonym: "positive regulation of lipid synthesis" EXACT [] synonym: "positive regulation of lipogenesis" EXACT [GOC:sl] synonym: "stimulation of lipid biosynthetic process" NARROW [] synonym: "up regulation of lipid biosynthetic process" EXACT [] synonym: "up-regulation of lipid biosynthetic process" EXACT [] synonym: "upregulation of lipid biosynthetic process" EXACT [] is_a: GO:0009891 ! positive regulation of biosynthetic process is_a: GO:0045834 ! positive regulation of lipid metabolic process is_a: GO:0046890 ! regulation of lipid biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0008610 ! lipid biosynthetic process relationship: positively_regulates GO:0008610 ! lipid biosynthetic process [Term] id: GO:0046890 name: regulation of lipid biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids." [GOC:ai] synonym: "regulation of lipid anabolism" EXACT [] synonym: "regulation of lipid biosynthesis" EXACT [] synonym: "regulation of lipid formation" EXACT [] synonym: "regulation of lipid synthesis" EXACT [] synonym: "regulation of lipogenesis" EXACT [GOC:sl] is_a: GO:0009889 ! regulation of biosynthetic process is_a: GO:0019216 ! regulation of lipid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0008610 ! lipid biosynthetic process relationship: regulates GO:0008610 ! lipid biosynthetic process [Term] id: GO:0046903 name: secretion namespace: biological_process def: "The controlled release of a substance by a cell or a tissue." [GOC:ai] subset: goslim_pir is_a: GO:0006810 ! transport [Term] id: GO:0046907 name: intracellular transport namespace: biological_process alt_id: GO:1902582 def: "The directed movement of substances within a cell." [GOC:ai] synonym: "single organism intracellular transport" RELATED [GOC:TermGenie] synonym: "single-organism intracellular transport" RELATED [] is_a: GO:0006810 ! transport is_a: GO:0051641 ! cellular localization is_a: GO:0051649 ! establishment of localization in cell intersection_of: GO:0006810 ! transport intersection_of: occurs_in GO:0005622 ! intracellular anatomical structure relationship: occurs_in GO:0005622 ! intracellular anatomical structure created_by: jl creation_date: 2013-12-18T14:04:50Z [Term] id: GO:0046928 name: regulation of neurotransmitter secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell." [GOC:ai] is_a: GO:0050804 ! modulation of chemical synaptic transmission is_a: GO:0051588 ! regulation of neurotransmitter transport is_a: GO:1903530 ! regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007269 ! neurotransmitter secretion relationship: regulates GO:0007269 ! neurotransmitter secretion [Term] id: GO:0046929 name: negative regulation of neurotransmitter secretion namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a neurotransmitter." [GOC:ai] synonym: "conotoxin activity" NARROW [] synonym: "down regulation of neurotransmitter secretion" EXACT [] synonym: "down-regulation of neurotransmitter secretion" EXACT [] synonym: "downregulation of neurotransmitter secretion" EXACT [] synonym: "inhibition of neurotransmitter secretion" NARROW [] is_a: GO:0046928 ! regulation of neurotransmitter secretion is_a: GO:0051589 ! negative regulation of neurotransmitter transport is_a: GO:1903531 ! negative regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007269 ! neurotransmitter secretion relationship: negatively_regulates GO:0007269 ! neurotransmitter secretion [Term] id: GO:0046942 name: carboxylic acid transport namespace: biological_process def: "The directed movement of carboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-)." [GOC:ai] is_a: GO:0015711 ! organic anion transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:29067 ! carboxylic acid anion relationship: has_primary_input CHEBI:29067 ! carboxylic acid anion [Term] id: GO:0046943 name: carboxylic acid transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of carboxylic acids from one side of a membrane to the other. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-)." [GOC:ai] xref: Reactome:R-HSA-390347 "Exchange of isocitrate and 2-oxoglutarate across the peroxisomal membrane" is_a: GO:0008514 ! organic anion transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:29067 ! carboxylic acid anion relationship: has_primary_input CHEBI:29067 ! carboxylic acid anion relationship: part_of GO:1905039 ! carboxylic acid transmembrane transport [Term] id: GO:0047496 name: vesicle transport along microtubule namespace: biological_process def: "The directed movement of a vesicle along a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination." [GOC:ecd, GOC:rl] synonym: "microtubule-based vesicle localization" EXACT [GOC:rl] is_a: GO:0072384 ! organelle transport along microtubule is_a: GO:0099518 ! vesicle cytoskeletal trafficking intersection_of: GO:0006810 ! transport intersection_of: has_primary_input GO:0031982 ! vesicle intersection_of: results_in_transport_along GO:0005874 ! microtubule [Term] id: GO:0048048 name: embryonic eye morphogenesis namespace: biological_process def: "The process occurring in the embryo by which the anatomical structures of the post-embryonic eye are generated and organized." [GOC:jid] is_a: GO:0048562 ! embryonic organ morphogenesis is_a: GO:0048592 ! eye morphogenesis [Term] id: GO:0048066 name: developmental pigmentation namespace: biological_process def: "The developmental process that results in the deposition of coloring matter in an organism, tissue or cell." [ISBN:0582227089] synonym: "pigmentation during development" RELATED [] is_a: GO:0043473 ! pigmentation [Term] id: GO:0048070 name: regulation of developmental pigmentation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism." [GOC:dph, GOC:jid, GOC:tb] synonym: "regulation of pigmentation during development" EXACT [GOC:dph, GOC:tb] is_a: GO:0120305 ! regulation of pigmentation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048066 ! developmental pigmentation relationship: regulates GO:0048066 ! developmental pigmentation [Term] id: GO:0048086 name: negative regulation of developmental pigmentation namespace: biological_process def: "Any process that decreases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism." [GOC:dph, GOC:jid, GOC:tb] synonym: "down regulation of developmental pigmentation" EXACT [GOC:dph, GOC:tb] synonym: "down-regulation of developmental pigmentation" EXACT [GOC:dph, GOC:tb] synonym: "downregulation of developmental pigmentation" EXACT [GOC:dph, GOC:tb] synonym: "inhibition of pigmentation" NARROW [] is_a: GO:0048070 ! regulation of developmental pigmentation is_a: GO:0048519 ! negative regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048066 ! developmental pigmentation relationship: negatively_regulates GO:0048066 ! developmental pigmentation [Term] id: GO:0048087 name: positive regulation of developmental pigmentation namespace: biological_process def: "Any process that increases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism." [GOC:dph, GOC:jid, GOC:tb] synonym: "activation of developmental pigmentation" NARROW [GOC:dph, GOC:tb] synonym: "stimulation of developmental pigmentation" NARROW [GOC:dph, GOC:tb] synonym: "up regulation of developmental pigmentation" EXACT [GOC:dph] synonym: "up-regulation of developmental pigmentation" EXACT [GOC:dph, GOC:tb] synonym: "upregulation of developmental pigmentation" EXACT [GOC:dph, GOC:tb] is_a: GO:0048070 ! regulation of developmental pigmentation is_a: GO:0048518 ! positive regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048066 ! developmental pigmentation relationship: positively_regulates GO:0048066 ! developmental pigmentation [Term] id: GO:0048103 name: somatic stem cell division namespace: biological_process def: "The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line." [GOC:jid, ISBN:0582227089] synonym: "somatic stem cell renewal" EXACT [] is_a: GO:0017145 ! stem cell division intersection_of: GO:0051301 ! cell division intersection_of: has_primary_input CL:0000723 ! somatic stem cell relationship: has_primary_input CL:0000723 ! somatic stem cell [Term] id: GO:0048132 name: female germ-line stem cell asymmetric division namespace: biological_process alt_id: GO:0048141 def: "The self-renewing division of a germline stem cell in the female gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the female gametes." [GOC:jid, GOC:mtg_sensu] synonym: "female germ-line stem cell renewal" EXACT [] is_a: GO:0098728 ! germline stem cell asymmetric division intersection_of: GO:0008356 ! asymmetric cell division intersection_of: has_primary_input CL:0000022 ! female germ line stem cell relationship: has_primary_input CL:0000022 ! female germ line stem cell relationship: in_taxon NCBITaxon:6656 {all_only="true"} ! Arthropoda relationship: only_in_taxon NCBITaxon:6656 ! Arthropoda relationship: part_of GO:0048477 ! oogenesis [Term] id: GO:0048137 name: spermatocyte division namespace: biological_process def: "The meiotic divisions undergone by the primary and secondary spermatocytes to produce haploid spermatids." [GOC:jid, GOC:pr, ISBN:0879694238] synonym: "spermatocyte cell division" EXACT [] is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0051301 ! cell division intersection_of: GO:0051301 ! cell division intersection_of: has_primary_input CL:0000017 ! spermatocyte relationship: has_primary_input CL:0000017 ! spermatocyte relationship: part_of GO:0007283 ! spermatogenesis [Term] id: GO:0048144 name: fibroblast proliferation namespace: biological_process def: "The multiplication or reproduction of fibroblast cells, resulting in the expansion of the fibroblast population." [GOC:jid] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000057 ! fibroblast relationship: acts_on_population_of CL:0000057 ! fibroblast [Term] id: GO:0048145 name: regulation of fibroblast proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of multiplication or reproduction of fibroblast cells." [GOC:jid] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048144 ! fibroblast proliferation relationship: regulates GO:0048144 ! fibroblast proliferation [Term] id: GO:0048146 name: positive regulation of fibroblast proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells." [GOC:jid] synonym: "activation of fibroblast proliferation" NARROW [] synonym: "stimulation of fibroblast proliferation" NARROW [] synonym: "up regulation of fibroblast proliferation" EXACT [] synonym: "up-regulation of fibroblast proliferation" EXACT [] synonym: "upregulation of fibroblast proliferation" EXACT [] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0048145 ! regulation of fibroblast proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048144 ! fibroblast proliferation relationship: positively_regulates GO:0048144 ! fibroblast proliferation [Term] id: GO:0048147 name: negative regulation of fibroblast proliferation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells." [GOC:jid] synonym: "down regulation of fibroblast proliferation" EXACT [] synonym: "down-regulation of fibroblast proliferation" EXACT [] synonym: "downregulation of fibroblast proliferation" EXACT [] synonym: "inhibition of fibroblast proliferation" NARROW [] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0048145 ! regulation of fibroblast proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048144 ! fibroblast proliferation relationship: negatively_regulates GO:0048144 ! fibroblast proliferation [Term] id: GO:0048193 name: Golgi vesicle transport namespace: biological_process def: "The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles." [GOC:jid, ISBN:0716731363, PMID:10219233] subset: goslim_yeast synonym: "Golgi-derived vesicle transport" RELATED [] is_a: GO:0016192 ! vesicle-mediated transport intersection_of: GO:0006810 ! transport intersection_of: results_in_transport_to_from_or_in GO:0005798 ! Golgi-associated vesicle relationship: results_in_transport_to_from_or_in GO:0005798 ! Golgi-associated vesicle [Term] id: GO:0048194 name: Golgi vesicle budding namespace: biological_process def: "The evagination of the Golgi membrane, resulting in formation of a vesicle." [GOC:jid, ISBN:0716731363, PMID:10219233] synonym: "dictyosome vesicle budding" NARROW [] synonym: "Golgi-derived vesicle budding" EXACT [] is_a: GO:0006900 ! vesicle budding from membrane intersection_of: GO:0006900 ! vesicle budding from membrane intersection_of: has_primary_output GO:0005798 ! Golgi-associated vesicle intersection_of: occurs_in GO:0000139 ! Golgi membrane relationship: has_primary_output GO:0005798 ! Golgi-associated vesicle relationship: occurs_in GO:0000139 ! Golgi membrane relationship: part_of GO:0048193 ! Golgi vesicle transport [Term] id: GO:0048199 name: vesicle targeting, to, from or within Golgi namespace: biological_process def: "The process in which vesicles are directed to specific destination membranes during transport to, from or within the Golgi apparatus; mediated by the addition of specific coat proteins, including COPI and COPII proteins and clathrin, to the membrane during vesicle formation." [GOC:jid, GOC:mah, ISBN:0716731363, PMID:10219233] synonym: "dictyosome vesicle targeting" NARROW [] synonym: "Golgi vesicle targeting" EXACT [] synonym: "vesicle targeting, to, from or within dictyosome" NARROW [] is_a: GO:0006903 ! vesicle targeting intersection_of: GO:0006903 ! vesicle targeting intersection_of: has_primary_input GO:0005798 ! Golgi-associated vesicle intersection_of: results_in_transport_to_from_or_in GO:0005794 ! Golgi apparatus relationship: has_primary_input GO:0005798 ! Golgi-associated vesicle relationship: part_of GO:0048193 ! Golgi vesicle transport relationship: results_in_transport_to_from_or_in GO:0005794 ! Golgi apparatus [Term] id: GO:0048209 name: regulation of vesicle targeting, to, from or within Golgi namespace: biological_process def: "Any process that modulates the frequency, rate, or destination of vesicle-mediated transport to, from or within the Golgi apparatus." [GOC:jid, GOC:mah, ISBN:0716731363, PMID:10219233] synonym: "regulation of Golgi vesicle targeting" EXACT [] is_a: GO:0060341 ! regulation of cellular localization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048199 ! vesicle targeting, to, from or within Golgi relationship: regulates GO:0048199 ! vesicle targeting, to, from or within Golgi [Term] id: GO:0048232 name: male gamete generation namespace: biological_process def: "Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction." [GOC:dph, GOC:jid] is_a: GO:0007276 ! gamete generation [Term] id: GO:0048240 name: sperm capacitation namespace: biological_process def: "A process required for sperm to reach fertilization competence. Sperm undergo an incompletely understood series of morphological and molecular maturational processes, termed capacitation, involving, among other processes, protein tyrosine phosphorylation and increased intracellular calcium." [GOC:jid, ISBN:978-3-642-58301-8, PMID:11820818] comment: Avian spermatozoa do not require a period of capacitation, since they are competent to fertilize the egg without a prolonged sojourn in the oviduct or in a capacitation medium in vitro. Therefore, sperm capacitation can only be applied to Aves to refer to gene products involved in processes that occur prior to sperm being deposited from the avian male. The term cannot apply to processes occurring in the avian female reproductive tract. synonym: "sperm activation" RELATED [PMID:23180860] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0048469 ! cell maturation relationship: part_of GO:0007286 ! spermatid development [Term] id: GO:0048243 name: norepinephrine secretion namespace: biological_process def: "The regulated release of norepinephrine by a cell. Norepinephrine is a catecholamine and it acts as a hormone and as a neurotransmitter of most of the sympathetic nervous system." [GOC:ef, GOC:jid] synonym: "noradrenaline secretion" EXACT [] is_a: GO:0015874 ! norepinephrine transport is_a: GO:0023061 ! signal release is_a: GO:0050432 ! catecholamine secretion intersection_of: GO:0046903 ! secretion intersection_of: has_primary_input CHEBI:72587 ! (R)-noradrenaline(1+) [Term] id: GO:0048251 name: elastic fiber assembly namespace: biological_process def: "Assembly of the extracellular matrix fibers that enables the matrix to recoil after transient stretching." [GOC:jid, PMID:10841810, PMID:12615674] synonym: "elastic fibre assembly" EXACT [] synonym: "elastin fiber assembly" EXACT [GOC:BHF] synonym: "elastin fibre assembly" EXACT [GOC:BHF] is_a: GO:0085029 ! extracellular matrix assembly is_a: GO:0097435 ! supramolecular fiber organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0071953 ! elastic fiber relationship: results_in_assembly_of GO:0071953 ! elastic fiber [Term] id: GO:0048280 name: vesicle fusion with Golgi apparatus namespace: biological_process def: "The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi." [GOC:jid] is_a: GO:0006906 ! vesicle fusion is_a: GO:0007030 ! Golgi organization intersection_of: GO:0009987 ! cellular process intersection_of: results_in_fusion_of GO:0005794 ! Golgi apparatus intersection_of: results_in_fusion_of GO:0031982 ! vesicle relationship: part_of GO:0048193 ! Golgi vesicle transport relationship: results_in_fusion_of GO:0005794 ! Golgi apparatus relationship: results_in_fusion_of GO:0031982 ! vesicle [Term] id: GO:0048284 name: organelle fusion namespace: biological_process def: "The creation of a single organelle from two or more organelles." [GOC:jid] subset: goslim_pir subset: goslim_yeast is_a: GO:0006996 ! organelle organization intersection_of: GO:0009987 ! cellular process intersection_of: results_in_fusion_of GO:0043226 ! organelle relationship: results_in_fusion_of GO:0043226 ! organelle [Term] id: GO:0048285 name: organelle fission namespace: biological_process def: "The creation of two or more organelles by division of one organelle." [GOC:jid] subset: goslim_pir subset: goslim_yeast is_a: GO:0006996 ! organelle organization intersection_of: GO:0009987 ! cellular process intersection_of: results_in_fission_of GO:0043226 ! organelle relationship: results_in_fission_of GO:0043226 ! organelle [Term] id: GO:0048288 name: nuclear membrane fusion involved in karyogamy namespace: biological_process def: "The joining of 2 or more lipid bilayer membranes that surround the nucleus during the creation of a single nucleus from multiple nuclei." [GOC:jid] synonym: "nuclear membrane fusion during karyogamy" RELATED [GOC:dph, GOC:tb] is_a: GO:0000740 ! nuclear membrane fusion intersection_of: GO:0000740 ! nuclear membrane fusion intersection_of: part_of GO:0000741 ! karyogamy relationship: part_of GO:0000741 ! karyogamy [Term] id: GO:0048308 name: organelle inheritance namespace: biological_process def: "The partitioning of organelles between daughter cells at cell division." [GOC:jid] subset: goslim_pir subset: goslim_yeast is_a: GO:0006996 ! organelle organization [Term] id: GO:0048313 name: Golgi inheritance namespace: biological_process def: "The partitioning of Golgi apparatus between daughter cells at cell division." [GOC:jid, PMID:12851069] synonym: "Golgi apparatus inheritance" EXACT [] synonym: "Golgi division" EXACT [GOC:ascb_2009, GOC:dph, GOC:tb] synonym: "Golgi partitioning" EXACT [] is_a: GO:0007030 ! Golgi organization is_a: GO:0048308 ! organelle inheritance intersection_of: GO:0048308 ! organelle inheritance intersection_of: results_in_distribution_of GO:0005794 ! Golgi apparatus relationship: results_in_distribution_of GO:0005794 ! Golgi apparatus [Term] id: GO:0048318 name: axial mesoderm development namespace: biological_process def: "The process whose specific outcome is the progression of the axial mesoderm over time, from its formation to the mature structure. The axial mesoderm includes the prechordal mesoderm and the chordamesoderm. It gives rise to the prechordal plate and to the notochord." [GOC:dgh] is_a: GO:0007498 ! mesoderm development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003068 ! axial mesoderm relationship: results_in_development_of UBERON:0003068 ! axial mesoderm [Term] id: GO:0048319 name: axial mesoderm morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the axial mesoderm are generated and organized." [GOC:go_curators] is_a: GO:0048332 ! mesoderm morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003068 ! axial mesoderm relationship: part_of GO:0048318 ! axial mesoderm development relationship: results_in_morphogenesis_of UBERON:0003068 ! axial mesoderm [Term] id: GO:0048320 name: axial mesoderm formation namespace: biological_process def: "The process that gives rise to the axial mesoderm. This process pertains to the initial formation of the structure from unspecified parts." [GOC:dgh] is_a: GO:0001707 ! mesoderm formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0003068 ! axial mesoderm relationship: part_of GO:0048319 ! axial mesoderm morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0003068 ! axial mesoderm [Term] id: GO:0048332 name: mesoderm morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the mesoderm are generated and organized." [GOC:go_curators] is_a: GO:0048729 ! tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000926 ! mesoderm relationship: part_of GO:0007498 ! mesoderm development relationship: results_in_morphogenesis_of UBERON:0000926 ! mesoderm [Term] id: GO:0048333 name: mesodermal cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized features of a mesoderm cell." [GOC:dgh] synonym: "mesoderm cell differentiation" EXACT [] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000222 ! mesodermal cell relationship: part_of GO:0001707 ! mesoderm formation relationship: results_in_acquisition_of_features_of CL:0000222 ! mesodermal cell [Term] id: GO:0048339 name: paraxial mesoderm development namespace: biological_process def: "The process whose specific outcome is the progression of the paraxial mesoderm over time, from its formation to the mature structure. The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube." [GOC:dgh] is_a: GO:0007498 ! mesoderm development is_a: GO:0060485 ! mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003077 ! paraxial mesoderm relationship: results_in_development_of UBERON:0003077 ! paraxial mesoderm [Term] id: GO:0048340 name: paraxial mesoderm morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the paraxial mesoderm are generated and organized." [GOC:go_curators] is_a: GO:0048332 ! mesoderm morphogenesis is_a: GO:0072132 ! mesenchyme morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003077 ! paraxial mesoderm relationship: part_of GO:0048339 ! paraxial mesoderm development relationship: results_in_morphogenesis_of UBERON:0003077 ! paraxial mesoderm [Term] id: GO:0048341 name: paraxial mesoderm formation namespace: biological_process def: "The process that gives rise to the paraxial mesoderm. This process pertains to the initial formation of the structure from unspecified parts." [GOC:dgh] is_a: GO:0001707 ! mesoderm formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0003077 ! paraxial mesoderm relationship: part_of GO:0048340 ! paraxial mesoderm morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0003077 ! paraxial mesoderm [Term] id: GO:0048368 name: lateral mesoderm development namespace: biological_process def: "The process whose specific outcome is the progression of the lateral mesoderm over time, from its formation to the mature structure." [GOC:go_curators] synonym: "lateral plate mesoderm development" EXACT [] is_a: GO:0007498 ! mesoderm development is_a: GO:0060485 ! mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003081 ! lateral plate mesoderm relationship: results_in_development_of UBERON:0003081 ! lateral plate mesoderm [Term] id: GO:0048369 name: lateral mesoderm morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the lateral mesoderm are generated and organized." [GOC:go_curators] synonym: "lateral plate mesoderm morphogenesis" EXACT [] is_a: GO:0048332 ! mesoderm morphogenesis is_a: GO:0072132 ! mesenchyme morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003081 ! lateral plate mesoderm relationship: part_of GO:0048368 ! lateral mesoderm development relationship: results_in_morphogenesis_of UBERON:0003081 ! lateral plate mesoderm [Term] id: GO:0048370 name: lateral mesoderm formation namespace: biological_process def: "The process that gives rise to the lateral mesoderm. This process pertains to the initial formation of the structure from unspecified parts." [GOC:jid] synonym: "lateral plate mesoderm biosynthesis" EXACT [] synonym: "lateral plate mesoderm formation" EXACT [] is_a: GO:0001707 ! mesoderm formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003081 ! lateral plate mesoderm relationship: part_of GO:0048369 ! lateral mesoderm morphogenesis relationship: results_in_morphogenesis_of UBERON:0003081 ! lateral plate mesoderm [Term] id: GO:0048389 name: intermediate mesoderm development namespace: biological_process def: "The process whose specific outcome is the progression of the intermediate mesoderm over time, from its formation to the mature structure. The intermediate mesoderm is located between the lateral mesoderm and the paraxial mesoderm. It develops into the kidney and gonads." [GOC:dgh] is_a: GO:0007498 ! mesoderm development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003064 ! intermediate mesoderm relationship: results_in_development_of UBERON:0003064 ! intermediate mesoderm [Term] id: GO:0048390 name: intermediate mesoderm morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the intermediate mesoderm are generated and organized." [GOC:go_curators] is_a: GO:0048332 ! mesoderm morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003064 ! intermediate mesoderm relationship: part_of GO:0048389 ! intermediate mesoderm development relationship: results_in_morphogenesis_of UBERON:0003064 ! intermediate mesoderm [Term] id: GO:0048391 name: intermediate mesoderm formation namespace: biological_process def: "The process that gives rise to the intermediate mesoderm. This process pertains to the initial formation of the structure from unspecified parts." [GOC:dgh] is_a: GO:0001707 ! mesoderm formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0003064 ! intermediate mesoderm relationship: part_of GO:0048390 ! intermediate mesoderm morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0003064 ! intermediate mesoderm [Term] id: GO:0048468 name: cell development namespace: biological_process def: "The cellular developmental process in which a specific cell progresses from an immature to a mature state. Cell development start once cell commitment has taken place." [GOC:go_curators] subset: goslim_candida synonym: "terminal differentiation" RELATED [GOC:dph, GOC:tb] is_a: GO:0048856 ! anatomical structure development is_a: GO:0048869 ! cellular developmental process intersection_of: GO:0008150 ! biological process intersection_of: results_in_development_of CL:0000000 ! cell relationship: part_of GO:0030154 ! cell differentiation relationship: results_in_development_of CL:0000000 ! cell property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24390" xsd:anyURI [Term] id: GO:0048469 name: cell maturation namespace: biological_process def: "The cellular developmental process, independent of morphogenetic (shape) change, that is required for a specific cell to attain its fully functional state." [GOC:go_curators] subset: goslim_pir synonym: "functional differentiation" RELATED [GOC:dph] is_a: GO:0048869 ! cellular developmental process is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of CL:0000000 ! cell relationship: part_of GO:0048468 ! cell development relationship: results_in_maturation_of CL:0000000 ! cell property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24390" xsd:anyURI [Term] id: GO:0048477 name: oogenesis namespace: biological_process alt_id: GO:0009993 alt_id: GO:0048157 def: "The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster." [GOC:kmv, GOC:mtg_sensu, GOC:pr] synonym: "ovum development" EXACT systematic_synonym [] xref: Wikipedia:Oogenesis is_a: GO:0007281 ! germ cell development is_a: GO:0007292 ! female gamete generation intersection_of: GO:0048468 ! cell development intersection_of: results_in_development_of CL:0000025 ! egg cell relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa relationship: results_in_development_of CL:0000025 ! egg cell [Term] id: GO:0048483 name: autonomic nervous system development namespace: biological_process def: "The process whose specific outcome is the progression of the autonomic nervous system over time, from its formation to the mature structure. The autonomic nervous system is composed of neurons that are not under conscious control, and is comprised of two antagonistic components, the sympathetic and parasympathetic nervous systems. The autonomic nervous system regulates key functions including the activity of the cardiac (heart) muscle, smooth muscles (e.g. of the gut), and glands." [FMA:9905, GOC:jid, GOC:sr] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002410 ! autonomic nervous system relationship: part_of GO:0007399 ! nervous system development relationship: results_in_development_of UBERON:0002410 ! autonomic nervous system [Term] id: GO:0048485 name: sympathetic nervous system development namespace: biological_process def: "The process whose specific outcome is the progression of the sympathetic nervous system over time, from its formation to the mature structure. The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter." [FMA:9906, GOC:jid, GOC:sr] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000013 ! sympathetic nervous system relationship: part_of GO:0048483 ! autonomic nervous system development relationship: results_in_development_of UBERON:0000013 ! sympathetic nervous system [Term] id: GO:0048505 name: regulation of timing of cell differentiation namespace: biological_process def: "The process controlling the activation and/or rate at which relatively unspecialized cells acquire specialized features. Any process that modulates the rate, frequency or extent of the XXX at a consistent predetermined time point during its development." [GOC:bf, GOC:dph, GOC:jid, GOC:tb] synonym: "timing of cell differentiation" RELATED [] is_a: GO:0040034 ! regulation of development, heterochronic is_a: GO:0045595 ! regulation of cell differentiation [Term] id: GO:0048511 name: rhythmic process namespace: biological_process def: "Any process pertinent to the generation and maintenance of rhythms in the physiology of an organism." [GOC:jid] subset: goslim_pir synonym: "rhythm" RELATED [] is_a: GO:0008150 ! biological process relationship: in_taxon NCBITaxon:131567 {all_only="true"} ! cellular organisms relationship: only_in_taxon NCBITaxon:131567 ! cellular organisms [Term] id: GO:0048513 name: animal organ development namespace: biological_process def: "Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." [GOC:dph, GOC:jid] synonym: "development of an organ" EXACT [] synonym: "organogenesis" EXACT [] xref: Wikipedia:Organogenesis is_a: GO:0048856 ! anatomical structure development property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/25943" xsd:anyURI [Term] id: GO:0048514 name: blood vessel morphogenesis namespace: biological_process def: "The process in which the anatomical structures of blood vessels are generated and organized. The blood vessel is the vasculature carrying blood." [GOC:jid] is_a: GO:0035239 ! tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001981 ! blood vessel relationship: part_of GO:0001568 ! blood vessel development relationship: results_in_morphogenesis_of UBERON:0001981 ! blood vessel [Term] id: GO:0048515 name: spermatid differentiation namespace: biological_process def: "The process whose specific outcome is the progression of a spermatid over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:dph, GOC:jid] synonym: "spermatid cell differentiation" EXACT [] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000018 ! spermatid relationship: part_of GO:0007283 ! spermatogenesis relationship: results_in_acquisition_of_features_of CL:0000018 ! spermatid [Term] id: GO:0048518 name: positive regulation of biological process namespace: biological_process alt_id: GO:0043119 def: "Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule." [GOC:jid] subset: gocheck_do_not_annotate synonym: "activation of biological process" NARROW [] synonym: "positive regulation of physiological process" EXACT [] synonym: "stimulation of biological process" NARROW [] synonym: "up regulation of biological process" EXACT [] synonym: "up-regulation of biological process" EXACT [] synonym: "upregulation of biological process" EXACT [] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0008150 ! biological process relationship: positively_regulates GO:0008150 ! biological process [Term] id: GO:0048519 name: negative regulation of biological process namespace: biological_process alt_id: GO:0043118 def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule." [GOC:jid] subset: gocheck_do_not_annotate synonym: "down regulation of biological process" EXACT [] synonym: "down-regulation of biological process" EXACT [] synonym: "downregulation of biological process" EXACT [] synonym: "inhibition of biological process" NARROW [] synonym: "negative regulation of physiological process" EXACT [] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0008150 ! biological process relationship: negatively_regulates GO:0008150 ! biological process [Term] id: GO:0048520 name: positive regulation of behavior namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli." [GOC:jid, GOC:pr] synonym: "activation of behavior" NARROW [] synonym: "stimulation of behavior" NARROW [] synonym: "up regulation of behavior" EXACT [] synonym: "up-regulation of behavior" EXACT [] synonym: "upregulation of behavior" EXACT [] is_a: GO:0050795 ! regulation of behavior is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007610 ! behavior relationship: positively_regulates GO:0007610 ! behavior [Term] id: GO:0048521 name: negative regulation of behavior namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli." [GOC:jid, GOC:pr] synonym: "down regulation of behavior" EXACT [] synonym: "down-regulation of behavior" EXACT [] synonym: "downregulation of behavior" EXACT [] synonym: "inhibition of behavior" NARROW [] is_a: GO:0050795 ! regulation of behavior is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007610 ! behavior relationship: negatively_regulates GO:0007610 ! behavior [Term] id: GO:0048522 name: positive regulation of cellular process namespace: biological_process alt_id: GO:0051242 def: "Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:jid] subset: gocheck_do_not_annotate synonym: "activation of cellular process" NARROW [] synonym: "positive regulation of cellular physiological process" EXACT [] synonym: "stimulation of cellular process" NARROW [] synonym: "up regulation of cellular process" EXACT [] synonym: "up-regulation of cellular process" EXACT [] synonym: "upregulation of cellular process" EXACT [] is_a: GO:0048518 ! positive regulation of biological process is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0009987 ! cellular process relationship: positively_regulates GO:0009987 ! cellular process [Term] id: GO:0048523 name: negative regulation of cellular process namespace: biological_process alt_id: GO:0051243 def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:jid] subset: gocheck_do_not_annotate synonym: "down regulation of cellular process" EXACT [] synonym: "down-regulation of cellular process" EXACT [] synonym: "downregulation of cellular process" EXACT [] synonym: "inhibition of cellular process" NARROW [] synonym: "negative regulation of cellular physiological process" EXACT [] is_a: GO:0048519 ! negative regulation of biological process is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0009987 ! cellular process relationship: negatively_regulates GO:0009987 ! cellular process [Term] id: GO:0048534 name: hematopoietic or lymphoid organ development namespace: biological_process def: "The process whose specific outcome is the progression of any organ involved in hematopoiesis (also known as hemopoiesis) or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation." [GOC:add, GOC:rl, ISBN:0781735149] synonym: "haematopoietic or lymphoid organ development" EXACT [] synonym: "haemopoietic or lymphoid organ development" EXACT [] synonym: "hemopoietic or lymphoid organ development" EXACT [] is_a: GO:0048513 ! animal organ development relationship: part_of GO:0002520 ! immune system development [Term] id: GO:0048536 name: spleen development namespace: biological_process def: "The process whose specific outcome is the progression of the spleen over time, from its formation to the mature structure. The spleen is a large vascular lymphatic organ composed of white and red pulp, involved both in hemopoietic and immune system functions." [GOC:add, ISBN:0781735149] is_a: GO:0048534 ! hematopoietic or lymphoid organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002106 ! spleen relationship: results_in_development_of UBERON:0002106 ! spleen [Term] id: GO:0048539 name: bone marrow development namespace: biological_process def: "The process whose specific outcome is the progression of the bone marrow over time, from its formation to the mature structure." [GOC:add, ISBN:0781735149] is_a: GO:0009888 ! tissue development is_a: GO:0048534 ! hematopoietic or lymphoid organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002371 ! bone marrow relationship: part_of GO:0060348 ! bone development relationship: results_in_development_of UBERON:0002371 ! bone marrow [Term] id: GO:0048545 name: response to steroid hormone namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus." [GOC:go_curators] synonym: "response to steroid hormone stimulus" EXACT [GOC:dos] is_a: GO:0009725 ! response to hormone is_a: GO:0014070 ! response to organic cyclic compound is_a: GO:0033993 ! response to lipid intersection_of: GO:0050896 ! response to stimulus intersection_of: has_primary_input CHEBI:26764 ! steroid hormone relationship: has_primary_input CHEBI:26764 ! steroid hormone [Term] id: GO:0048546 name: digestive tract morphogenesis namespace: biological_process alt_id: GO:0048547 def: "The process in which the anatomical structures of the digestive tract are generated and organized. The digestive tract is the anatomical structure through which food passes and is processed." [GOC:dph, GOC:go_curators, PMID:12618131] synonym: "alimentary canal morphogenesis" EXACT [] synonym: "digestive tube morphogenesis" EXACT [] synonym: "gastrointestinal tract morphogenesis" EXACT [] synonym: "gut morphogenesis" BROAD [GOC:dph] synonym: "intestinal morphogenesis" NARROW [] is_a: GO:0035239 ! tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001555 ! digestive tract relationship: part_of GO:0048565 ! digestive tract development relationship: results_in_morphogenesis_of UBERON:0001555 ! digestive tract [Term] id: GO:0048562 name: embryonic organ morphogenesis namespace: biological_process def: "Morphogenesis, during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." [GOC:jid] is_a: GO:0009887 ! animal organ morphogenesis is_a: GO:0048598 ! embryonic morphogenesis relationship: part_of GO:0048568 ! embryonic organ development [Term] id: GO:0048565 name: digestive tract development namespace: biological_process def: "The process whose specific outcome is the progression of the digestive tract over time, from its formation to the mature structure. The digestive tract is the anatomical structure through which food passes and is processed." [GOC:go_curators] synonym: "gut development" BROAD [GOC:dph] synonym: "intestinal development" NARROW [] synonym: "intestine development" NARROW [] is_a: GO:0035295 ! tube development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001555 ! digestive tract relationship: part_of GO:0055123 ! digestive system development relationship: results_in_development_of UBERON:0001555 ! digestive tract [Term] id: GO:0048568 name: embryonic organ development namespace: biological_process def: "Development, taking place during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." [GOC:jid] synonym: "embryonic organogenesis" EXACT [] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: part_of GO:0009790 ! embryo development intersection_of: results_in_development_of UBERON:0000062 ! organ relationship: part_of GO:0009790 ! embryo development relationship: results_in_development_of UBERON:0000062 ! organ [Term] id: GO:0048570 name: notochord morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the notochord are generated and organized. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column." [GOC:jid] is_a: GO:0048562 ! embryonic organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002328 ! notochord relationship: part_of GO:0030903 ! notochord development relationship: results_in_morphogenesis_of UBERON:0002328 ! notochord [Term] id: GO:0048580 name: regulation of post-embryonic development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure." [GOC:jid] is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0009791 ! post-embryonic development relationship: regulates GO:0009791 ! post-embryonic development [Term] id: GO:0048581 name: negative regulation of post-embryonic development namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure." [GOC:jid] synonym: "down regulation of post-embryonic development" EXACT [] synonym: "down-regulation of post-embryonic development" EXACT [] synonym: "downregulation of post-embryonic development" EXACT [] synonym: "inhibition of post-embryonic development" NARROW [] is_a: GO:0048580 ! regulation of post-embryonic development is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0009791 ! post-embryonic development relationship: negatively_regulates GO:0009791 ! post-embryonic development [Term] id: GO:0048582 name: positive regulation of post-embryonic development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure." [GOC:jid] synonym: "activation of post-embryonic development" NARROW [] synonym: "stimulation of post-embryonic development" NARROW [] synonym: "up regulation of post-embryonic development" EXACT [] synonym: "up-regulation of post-embryonic development" EXACT [] synonym: "upregulation of post-embryonic development" EXACT [] is_a: GO:0048580 ! regulation of post-embryonic development is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0009791 ! post-embryonic development relationship: positively_regulates GO:0009791 ! post-embryonic development [Term] id: GO:0048583 name: regulation of response to stimulus namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus." [GOC:jid] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_manually_annotate is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0050896 ! response to stimulus relationship: regulates GO:0050896 ! response to stimulus [Term] id: GO:0048584 name: positive regulation of response to stimulus namespace: biological_process def: "Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus." [GOC:jid] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_manually_annotate synonym: "activation of response to stimulus" NARROW [] synonym: "stimulation of response to stimulus" NARROW [] synonym: "up regulation of response to stimulus" EXACT [] synonym: "up-regulation of response to stimulus" EXACT [] synonym: "upregulation of response to stimulus" EXACT [] is_a: GO:0048518 ! positive regulation of biological process is_a: GO:0048583 ! regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0050896 ! response to stimulus relationship: positively_regulates GO:0050896 ! response to stimulus [Term] id: GO:0048585 name: negative regulation of response to stimulus namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus." [GOC:jid] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_manually_annotate synonym: "down regulation of response to stimulus" EXACT [] synonym: "down-regulation of response to stimulus" EXACT [] synonym: "downregulation of response to stimulus" EXACT [] synonym: "inhibition of response to stimulus" NARROW [] is_a: GO:0048519 ! negative regulation of biological process is_a: GO:0048583 ! regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0050896 ! response to stimulus relationship: negatively_regulates GO:0050896 ! response to stimulus [Term] id: GO:0048588 name: developmental cell growth namespace: biological_process def: "The growth of a cell, where growth contributes to the progression of the cell over time from one condition to another." [GOC:go_curators, GOC:isa_complete] subset: gocheck_do_not_annotate synonym: "developmental growth of a unicellular organism" EXACT [] is_a: GO:0016049 ! cell growth is_a: GO:0048589 ! developmental growth relationship: part_of GO:0048468 ! cell development property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI [Term] id: GO:0048589 name: developmental growth namespace: biological_process def: "The increase in size or mass of an entire organism, a part of an organism or a cell, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another." [GOC:go_curators] is_a: GO:0040007 ! growth intersection_of: GO:0040007 ! growth intersection_of: part_of GO:0032502 ! developmental process relationship: part_of GO:0032502 ! developmental process [Term] id: GO:0048592 name: eye morphogenesis namespace: biological_process alt_id: GO:0048748 def: "The process in which the anatomical structures of the eye are generated and organized." [GOC:jid, GOC:mtg_sensu] is_a: GO:0090596 ! sensory organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000970 ! eye relationship: part_of GO:0001654 ! eye development relationship: results_in_morphogenesis_of UBERON:0000970 ! eye [Term] id: GO:0048593 name: camera-type eye morphogenesis namespace: biological_process alt_id: GO:0048594 alt_id: GO:0048595 def: "The process in which the anatomical structures of the eye are generated and organized. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field." [GOC:jid, GOC:mtg_sensu] synonym: "camera-style eye morphogenesis" EXACT [GOC:dph] is_a: GO:0048592 ! eye morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000019 ! camera-type eye relationship: part_of GO:0043010 ! camera-type eye development relationship: results_in_morphogenesis_of UBERON:0000019 ! camera-type eye [Term] id: GO:0048596 name: embryonic camera-type eye morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the eye are generated and organized during embryonic development." [GOC:jid, GOC:mtg_sensu] synonym: "embryonic eye morphogenesis" BROAD [] is_a: GO:0048048 ! embryonic eye morphogenesis relationship: part_of GO:0031076 ! embryonic camera-type eye development relationship: part_of GO:0048593 ! camera-type eye morphogenesis [Term] id: GO:0048598 name: embryonic morphogenesis namespace: biological_process alt_id: GO:0048828 def: "The process in which anatomical structures are generated and organized during the embryonic phase. The embryonic phase begins with zygote formation. The end of the embryonic phase is organism-specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants." [GOC:jid, GOC:mtg_sensu] synonym: "embryonic anatomical structure morphogenesis" EXACT [GOC:dph, GOC:tb] is_a: GO:0009653 ! anatomical structure morphogenesis relationship: part_of GO:0009790 ! embryo development [Term] id: GO:0048599 name: oocyte development namespace: biological_process def: "The process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." [GOC:go_curators] is_a: GO:0007281 ! germ cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000023 ! oocyte relationship: part_of GO:0009994 ! oocyte differentiation relationship: results_in_development_of CL:0000023 ! oocyte [Term] id: GO:0048601 name: oocyte morphogenesis namespace: biological_process def: "The process in which the structures of an oocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of an oocyte." [GOC:go_curators] synonym: "oocyte morphogenesis during differentiation" EXACT [] is_a: GO:0000902 ! cell morphogenesis is_a: GO:0003006 ! developmental process involved in reproduction intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of CL:0000023 ! oocyte relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0048599 ! oocyte development relationship: results_in_morphogenesis_of CL:0000023 ! oocyte [Term] id: GO:0048608 name: reproductive structure development namespace: biological_process def: "The reproductive developmental process whose specific outcome is the progression of somatic structures that will be used in the process of creating new individuals from one or more parents, from their formation to the mature structures." [GOC:dph, GOC:isa_complete, GOC:jid] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0048856 ! anatomical structure development relationship: part_of GO:0061458 ! reproductive system development property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23445" xsd:anyURI [Term] id: GO:0048609 name: multicellular organismal reproductive process namespace: biological_process def: "The process, occurring above the cellular level, that is pertinent to the reproductive function of a multicellular organism. This includes the integrated processes at the level of tissues and organs." [GOC:dph, GOC:jid, GOC:tb] synonym: "organismal reproductive process" BROAD [] synonym: "reproductive process in a multicellular organism" EXACT [] is_a: GO:0022414 ! reproductive process relationship: part_of GO:0032504 ! multicellular organism reproduction [Term] id: GO:0048627 name: myoblast development namespace: biological_process def: "The process whose specific outcome is the progression of the myoblast over time, from its formation to the mature structure. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:dph, GOC:mtg_muscle] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000056 ! myoblast relationship: part_of GO:0045445 ! myoblast differentiation relationship: results_in_development_of CL:0000056 ! myoblast [Term] id: GO:0048628 name: myoblast maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for a myoblast to attain its fully functional state. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:dph, GOC:mtg_muscle] is_a: GO:0048469 ! cell maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of CL:0000056 ! myoblast relationship: part_of GO:0048627 ! myoblast development relationship: results_in_maturation_of CL:0000056 ! myoblast [Term] id: GO:0048630 name: skeletal muscle tissue growth namespace: biological_process def: "The increase in size or mass of a skeletal muscle. This may be due to a change in the fiber number or size." [GOC:lm, PMID:15726494, PMID:15907921] is_a: GO:0048589 ! developmental growth intersection_of: GO:0048589 ! developmental growth intersection_of: results_in_growth_of UBERON:0001134 ! skeletal muscle tissue relationship: part_of GO:0007519 ! skeletal muscle tissue development relationship: results_in_growth_of UBERON:0001134 ! skeletal muscle tissue [Term] id: GO:0048631 name: regulation of skeletal muscle tissue growth namespace: biological_process def: "Any process that modulates the frequency, rate or extent of skeletal muscle growth." [GOC:lm, PMID:15726494, PMID:15907921] is_a: GO:0048638 ! regulation of developmental growth intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048630 ! skeletal muscle tissue growth relationship: regulates GO:0048630 ! skeletal muscle tissue growth [Term] id: GO:0048632 name: negative regulation of skeletal muscle tissue growth namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle growth." [GOC:lm, PMID:15726494, PMID:15907921] synonym: "down regulation of skeletal muscle growth" EXACT [] synonym: "down-regulation of skeletal muscle growth" EXACT [] synonym: "downregulation of skeletal muscle growth" EXACT [] synonym: "inhibition of skeletal muscle growth" NARROW [] is_a: GO:0048631 ! regulation of skeletal muscle tissue growth is_a: GO:0048640 ! negative regulation of developmental growth intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048630 ! skeletal muscle tissue growth relationship: negatively_regulates GO:0048630 ! skeletal muscle tissue growth [Term] id: GO:0048633 name: positive regulation of skeletal muscle tissue growth namespace: biological_process def: "Any process that activates, maintains or increases the rate of skeletal muscle growth." [GOC:lm, PMID:15726494, PMID:15907921] synonym: "activation of skeletal muscle growth" NARROW [] synonym: "stimulation of skeletal muscle growth" NARROW [] synonym: "up regulation of skeletal muscle growth" EXACT [] synonym: "up-regulation of skeletal muscle growth" EXACT [] synonym: "upregulation of skeletal muscle growth" EXACT [] is_a: GO:0048631 ! regulation of skeletal muscle tissue growth is_a: GO:0048639 ! positive regulation of developmental growth is_a: GO:0048643 ! positive regulation of skeletal muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048630 ! skeletal muscle tissue growth relationship: positively_regulates GO:0048630 ! skeletal muscle tissue growth [Term] id: GO:0048634 name: regulation of muscle organ development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of muscle development." [GOC:go_curators] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007517 ! muscle organ development relationship: regulates GO:0007517 ! muscle organ development [Term] id: GO:0048635 name: negative regulation of muscle organ development namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of muscle development." [GOC:go_curators] synonym: "down regulation of muscle development" EXACT [] synonym: "down-regulation of muscle development" EXACT [] synonym: "downregulation of muscle development" EXACT [] synonym: "inhibition of muscle development" NARROW [] is_a: GO:0048634 ! regulation of muscle organ development is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007517 ! muscle organ development relationship: negatively_regulates GO:0007517 ! muscle organ development [Term] id: GO:0048636 name: positive regulation of muscle organ development namespace: biological_process def: "Any process that activates, maintains or increases the rate of muscle development." [GOC:go_curators] synonym: "activation of muscle development" NARROW [] synonym: "stimulation of muscle development" NARROW [] synonym: "up regulation of muscle development" EXACT [] synonym: "up-regulation of muscle development" EXACT [] synonym: "upregulation of muscle development" EXACT [] is_a: GO:0048634 ! regulation of muscle organ development is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007517 ! muscle organ development relationship: positively_regulates GO:0007517 ! muscle organ development [Term] id: GO:0048638 name: regulation of developmental growth namespace: biological_process def: "Any process that modulates the frequency, rate or extent of developmental growth." [GOC:go_curators] is_a: GO:0040008 ! regulation of growth is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048589 ! developmental growth relationship: regulates GO:0048589 ! developmental growth [Term] id: GO:0048639 name: positive regulation of developmental growth namespace: biological_process def: "Any process that activates, maintains or increases the rate of developmental growth." [GOC:go_curators] synonym: "activation of developmental growth" NARROW [] synonym: "stimulation of developmental growth" NARROW [] synonym: "up regulation of developmental growth" EXACT [] synonym: "up-regulation of developmental growth" EXACT [] synonym: "upregulation of developmental growth" EXACT [] is_a: GO:0045927 ! positive regulation of growth is_a: GO:0048638 ! regulation of developmental growth is_a: GO:0051094 ! positive regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048589 ! developmental growth relationship: positively_regulates GO:0048589 ! developmental growth [Term] id: GO:0048640 name: negative regulation of developmental growth namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of developmental growth." [GOC:go_curators] synonym: "down regulation of developmental growth" EXACT [] synonym: "down-regulation of developmental growth" EXACT [] synonym: "downregulation of developmental growth" EXACT [] synonym: "inhibition of developmental growth" NARROW [] is_a: GO:0045926 ! negative regulation of growth is_a: GO:0048638 ! regulation of developmental growth is_a: GO:0051093 ! negative regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048589 ! developmental growth relationship: negatively_regulates GO:0048589 ! developmental growth [Term] id: GO:0048641 name: regulation of skeletal muscle tissue development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of skeletal muscle tissue development." [GOC:go_curators] is_a: GO:0016202 ! regulation of striated muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007519 ! skeletal muscle tissue development relationship: regulates GO:0007519 ! skeletal muscle tissue development [Term] id: GO:0048642 name: negative regulation of skeletal muscle tissue development namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle tissue development." [GOC:go_curators] synonym: "down regulation of skeletal muscle development" EXACT [] synonym: "down-regulation of skeletal muscle development" EXACT [] synonym: "downregulation of skeletal muscle development" EXACT [] synonym: "inhibition of skeletal muscle development" NARROW [] is_a: GO:0045843 ! negative regulation of striated muscle tissue development is_a: GO:0048641 ! regulation of skeletal muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007519 ! skeletal muscle tissue development relationship: negatively_regulates GO:0007519 ! skeletal muscle tissue development [Term] id: GO:0048643 name: positive regulation of skeletal muscle tissue development namespace: biological_process def: "Any process that activates, maintains or increases the rate of skeletal muscle tissue development." [GOC:go_curators] synonym: "activation of skeletal muscle development" NARROW [] synonym: "stimulation of skeletal muscle development" NARROW [] synonym: "up regulation of skeletal muscle development" EXACT [] synonym: "up-regulation of skeletal muscle development" EXACT [] synonym: "upregulation of skeletal muscle development" EXACT [] is_a: GO:0045844 ! positive regulation of striated muscle tissue development is_a: GO:0048641 ! regulation of skeletal muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007519 ! skeletal muscle tissue development relationship: positively_regulates GO:0007519 ! skeletal muscle tissue development [Term] id: GO:0048644 name: muscle organ morphogenesis namespace: biological_process def: "The process in which the anatomical structures of muscle are generated and organized." [GOC:jid] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001630 ! muscle organ relationship: part_of GO:0007517 ! muscle organ development relationship: results_in_morphogenesis_of UBERON:0001630 ! muscle organ [Term] id: GO:0048645 name: animal organ formation namespace: biological_process def: "The process pertaining to the initial formation of an animal organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment. Organs are a natural part or structure in an animal or a plant, capable of performing some special action (termed its function), which is essential to the life or well-being of the whole. The heart and lungs are organs of animals, and the petal and leaf are organs of plants. In animals the organs are generally made up of several tissues, one of which usually predominates, and determines the principal function of the organ." [GOC:dph, GOC:jid] synonym: "animal organ primordium initiation" NARROW [] synonym: "initiation of an animal organ primordium" NARROW [] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0003103 ! compound organ relationship: part_of GO:0009887 ! animal organ morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0003103 ! compound organ [Term] id: GO:0048646 name: anatomical structure formation involved in morphogenesis namespace: biological_process def: "The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." [GOC:dph, GOC:jid, GOC:tb] comment: Note that, for example, the formation of a pseudopod in an amoeba would not be considered formation involved in morphogenesis because it would not be thought of as the formation of an anatomical structure that was part of the shaping of the amoeba during its development. The formation of an axon from a neuron would be considered the formation of an anatomical structure involved in morphogenesis because it contributes to the creation of the form of the neuron in a developmental sense. subset: goslim_chembl synonym: "formation of an anatomical structure involved in morphogenesis" EXACT [GOC:dph, GOC:tb] is_a: GO:0032502 ! developmental process relationship: part_of GO:0009653 ! anatomical structure morphogenesis [Term] id: GO:0048659 name: smooth muscle cell proliferation namespace: biological_process def: "The multiplication or reproduction of smooth muscle cells, resulting in the expansion of a cell population." [CL:0000192, GOC:ebc, PMID:1840698] synonym: "SMC proliferation" EXACT [] is_a: GO:0033002 ! muscle cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000192 ! smooth muscle cell relationship: acts_on_population_of CL:0000192 ! smooth muscle cell [Term] id: GO:0048660 name: regulation of smooth muscle cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of smooth muscle cell proliferation." [CL:0000192, GOC:ebc] synonym: "regulation of SMC proliferation" EXACT [] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048659 ! smooth muscle cell proliferation relationship: regulates GO:0048659 ! smooth muscle cell proliferation [Term] id: GO:0048661 name: positive regulation of smooth muscle cell proliferation namespace: biological_process def: "Any process that activates or increases the rate or extent of smooth muscle cell proliferation." [CL:0000192, GOC:ebc] synonym: "activation of smooth muscle cell proliferation" NARROW [] synonym: "positive regulation of SMC proliferation" EXACT [] synonym: "stimulation of smooth muscle cell proliferation" NARROW [] synonym: "up regulation of smooth muscle cell proliferation" EXACT [] synonym: "up-regulation of smooth muscle cell proliferation" EXACT [] synonym: "upregulation of smooth muscle cell proliferation" EXACT [] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0048660 ! regulation of smooth muscle cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048659 ! smooth muscle cell proliferation relationship: positively_regulates GO:0048659 ! smooth muscle cell proliferation [Term] id: GO:0048662 name: negative regulation of smooth muscle cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of smooth muscle cell proliferation." [CL:0000192, GOC:ebc] synonym: "down regulation of smooth muscle cell proliferation" EXACT [] synonym: "down-regulation of smooth muscle cell proliferation" EXACT [] synonym: "downregulation of smooth muscle cell proliferation" EXACT [] synonym: "inhibition of smooth muscle cell proliferation" NARROW [] synonym: "negative regulation of SMC proliferation" EXACT [] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0048660 ! regulation of smooth muscle cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048659 ! smooth muscle cell proliferation relationship: negatively_regulates GO:0048659 ! smooth muscle cell proliferation [Term] id: GO:0048666 name: neuron development namespace: biological_process def: "The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:dph] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000540 ! neuron relationship: part_of GO:0030182 ! neuron differentiation relationship: results_in_development_of CL:0000540 ! neuron [Term] id: GO:0048667 name: cell morphogenesis involved in neuron differentiation namespace: biological_process def: "The process in which the structures of a neuron are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a neuron." [GOC:dph, GOC:tb] synonym: "neuron morphogenesis involved in differentiation" EXACT [GOC:dph, GOC:tb] is_a: GO:0000902 ! cell morphogenesis intersection_of: GO:0000902 ! cell morphogenesis intersection_of: part_of GO:0030182 ! neuron differentiation relationship: part_of GO:0048666 ! neuron development [Term] id: GO:0048699 name: generation of neurons namespace: biological_process def: "The process in which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons." [GOC:nln] synonym: "neuron generation" EXACT [] is_a: GO:0022008 ! neurogenesis [Term] id: GO:0048705 name: skeletal system morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the skeleton are generated and organized." [GOC:dph, GOC:dsf, GOC:jid, GOC:tb] synonym: "skeletal morphogenesis" EXACT [GOC:dph, GOC:tb] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001434 ! skeletal system relationship: part_of GO:0001501 ! skeletal system development relationship: results_in_morphogenesis_of UBERON:0001434 ! skeletal system [Term] id: GO:0048729 name: tissue morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a tissue are generated and organized." [GOC:dph, GOC:jid] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000479 ! tissue relationship: part_of GO:0009888 ! tissue development relationship: results_in_morphogenesis_of UBERON:0000479 ! tissue [Term] id: GO:0048730 name: epidermis morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the epidermis are generated and organized. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species." [GOC:jid, UBERON:0001003] synonym: "hypodermis morphogenesis" RELATED [GOC:kmv, GOC:rk] is_a: GO:0002009 ! morphogenesis of an epithelium intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0007376 ! outer epithelium relationship: part_of GO:0008544 ! epidermis development relationship: results_in_morphogenesis_of UBERON:0007376 ! outer epithelium [Term] id: GO:0048731 name: system development namespace: biological_process def: "The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process." [GOC:dph, GOC:jid] subset: goslim_mouse is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000467 ! anatomical system relationship: part_of GO:0007275 ! multicellular organism development relationship: results_in_development_of UBERON:0000467 ! anatomical system [Term] id: GO:0048732 name: gland development namespace: biological_process def: "The process whose specific outcome is the progression of a gland over time, from its formation to the mature structure. A gland is an organ specialised for secretion." [GOC:jid] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002530 ! gland relationship: results_in_development_of UBERON:0002530 ! gland [Term] id: GO:0048736 name: appendage development namespace: biological_process def: "The process whose specific outcome is the progression of an appendage over time, from its formation to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch." [GOC:jid, GOC:rc] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000026 ! appendage relationship: part_of GO:0007275 ! multicellular organism development relationship: results_in_development_of UBERON:0000026 ! appendage [Term] id: GO:0048738 name: cardiac muscle tissue development namespace: biological_process def: "The process whose specific outcome is the progression of cardiac muscle over time, from its formation to the mature structure." [GOC:dph, GOC:jid, GOC:lm] synonym: "heart muscle development" EXACT [] is_a: GO:0014706 ! striated muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001133 ! cardiac muscle tissue relationship: part_of GO:0007507 ! heart development relationship: results_in_development_of UBERON:0001133 ! cardiac muscle tissue [Term] id: GO:0048741 name: skeletal muscle fiber development namespace: biological_process def: "The process whose specific outcome is the progression of the skeletal muscle fiber over time, from its formation to the mature structure. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast." [GOC:dph, GOC:ef, GOC:jid, GOC:lm, GOC:mtg_muscle] synonym: "skeletal muscle fibre development" EXACT [] synonym: "skeletal myofiber development" EXACT [] synonym: "skeletal myofibre development" EXACT [] is_a: GO:0014904 ! myotube cell development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of CL:0008002 ! skeletal muscle fiber relationship: part_of GO:0007519 ! skeletal muscle tissue development relationship: results_in_development_of CL:0008002 ! skeletal muscle fiber [Term] id: GO:0048742 name: regulation of skeletal muscle fiber development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast." [GOC:dph, GOC:jid, GOC:mtg_muscle, GOC:sm] synonym: "regulation of skeletal muscle fibre development" EXACT [] synonym: "regulation of skeletal myofiber development" EXACT [] synonym: "regulation of skeletal myofibre development" EXACT [] is_a: GO:0010830 ! regulation of myotube differentiation is_a: GO:0060284 ! regulation of cell development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048741 ! skeletal muscle fiber development relationship: regulates GO:0048741 ! skeletal muscle fiber development [Term] id: GO:0048743 name: positive regulation of skeletal muscle fiber development namespace: biological_process def: "Any process that activates, maintains or increases the rate of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast." [GOC:dph, GOC:jid, GOC:lm, GOC:mtg_muscle] synonym: "activation of skeletal muscle fiber development" NARROW [] synonym: "positive regulation of skeletal muscle fibre development" EXACT [] synonym: "positive regulation of skeletal myofiber development" EXACT [] synonym: "positive regulation of skeletal myofibre development" EXACT [] synonym: "stimulation of skeletal muscle fiber development" NARROW [] synonym: "up regulation of skeletal muscle fiber development" EXACT [] synonym: "up-regulation of skeletal muscle fiber development" EXACT [] synonym: "upregulation of skeletal muscle fiber development" EXACT [] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0048643 ! positive regulation of skeletal muscle tissue development is_a: GO:0048742 ! regulation of skeletal muscle fiber development is_a: GO:0051155 ! positive regulation of striated muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048741 ! skeletal muscle fiber development relationship: positively_regulates GO:0048741 ! skeletal muscle fiber development [Term] id: GO:0048744 name: negative regulation of skeletal muscle fiber development namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast." [GOC:dph, GOC:jid, GOC:lm, GOC:mtg_muscle] synonym: "down regulation of skeletal muscle fiber development" EXACT [] synonym: "down-regulation of skeletal muscle fiber development" EXACT [] synonym: "downregulation of skeletal muscle fiber development" EXACT [] synonym: "inhibition of skeletal muscle fiber development" NARROW [] synonym: "negative regulation of skeletal muscle fibre development" EXACT [] synonym: "negative regulation of skeletal myofiber development" EXACT [] synonym: "negative regulation of skeletal myofibre development" EXACT [] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0048742 ! regulation of skeletal muscle fiber development is_a: GO:0051154 ! negative regulation of striated muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048741 ! skeletal muscle fiber development relationship: negatively_regulates GO:0048741 ! skeletal muscle fiber development [Term] id: GO:0048745 name: smooth muscle tissue development namespace: biological_process def: "The process whose specific outcome is the progression of smooth muscle over time, from its formation to the mature structure." [GOC:dph, GOC:jid, GOC:lm] is_a: GO:0060537 ! muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001135 ! smooth muscle tissue relationship: results_in_development_of UBERON:0001135 ! smooth muscle tissue [Term] id: GO:0048749 name: compound eye development namespace: biological_process alt_id: GO:0007456 def: "The process whose specific outcome is the progression of the compound eye over time, from its formation to the mature structure. The compound eye is an organ of sight that contains multiple repeating units, often arranged hexagonally. Each unit has its own lens and photoreceptor cell(s) and can generate either a single pixelated image or multiple images, per eye." [GOC:jid, GOC:mtg_sensu, Wikipedia:Eye] synonym: "insect-type retina development" EXACT [PMID:11735386] is_a: GO:0001654 ! eye development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000018 ! compound eye relationship: results_in_development_of UBERON:0000018 ! compound eye [Term] id: GO:0048753 name: pigment granule organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pigment granule." [GOC:rc] subset: goslim_pir synonym: "pigment granule organisation" EXACT [] synonym: "pigment granule organization and biogenesis" RELATED [GOC:mah] is_a: GO:0016050 ! vesicle organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0048770 ! pigment granule relationship: part_of GO:0033059 ! cellular pigmentation relationship: results_in_organization_of GO:0048770 ! pigment granule [Term] id: GO:0048754 name: branching morphogenesis of an epithelial tube namespace: biological_process def: "The process in which the anatomical structures of branches in an epithelial tube are generated and organized. A tube is a long hollow cylinder." [GOC:dgh, GOC:dph, GOC:jid] synonym: "tubulogenesis" RELATED [GOC:dph, GOC:tb] is_a: GO:0035239 ! tube morphogenesis is_a: GO:0061138 ! morphogenesis of a branching epithelium intersection_of: GO:0001763 ! morphogenesis of a branching structure intersection_of: results_in_morphogenesis_of UBERON:0000025 ! tube relationship: part_of GO:0060562 ! epithelial tube morphogenesis [Term] id: GO:0048755 name: branching morphogenesis of a nerve namespace: biological_process def: "The process in which the anatomical structures of branches in a nerve are generated and organized. This term refers to an anatomical structure (nerve) not a cell (neuron)." [GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0001763 ! morphogenesis of a branching structure intersection_of: GO:0001763 ! morphogenesis of a branching structure intersection_of: results_in_morphogenesis_of UBERON:0001021 ! nerve relationship: part_of GO:0007399 ! nervous system development relationship: results_in_morphogenesis_of UBERON:0001021 ! nerve [Term] id: GO:0048762 name: mesenchymal cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types." [GOC:dph, GOC:jid] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0008019 ! mesenchymal cell relationship: part_of GO:0060485 ! mesenchyme development relationship: results_in_acquisition_of_features_of CL:0008019 ! mesenchymal cell [Term] id: GO:0048770 name: pigment granule namespace: cellular_component def: "A small, subcellular membrane-bounded vesicle containing pigment and/or pigment precursor molecules. Pigment granule biogenesis is poorly understood, as pigment granules are derived from multiple sources including the endoplasmic reticulum, coated vesicles, lysosomes, and endosomes." [GOC:jid, GOC:mh] is_a: GO:0031410 ! cytoplasmic vesicle [Term] id: GO:0048793 name: pronephros development namespace: biological_process def: "The process whose specific outcome is the progression of the pronephros over time, from its formation to the mature structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life." [GOC:bf, GOC:mtg_kidney_jan10, PMID:10535314, PMID:15968585, PMID:18322540, XAO:00002000, ZFA:0000151] synonym: "pronephric kidney development" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0001822 ! kidney development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002120 ! pronephros relationship: results_in_development_of UBERON:0002120 ! pronephros [Term] id: GO:0048799 name: animal organ maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for an animal organ to attain its fully functional state. An organ is a tissue or set of tissues that work together to perform a specific function or functions." [GOC:curators] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of UBERON:0000062 ! organ relationship: part_of GO:0048513 ! animal organ development relationship: results_in_maturation_of UBERON:0000062 ! organ [Term] id: GO:0048806 name: genitalia development namespace: biological_process def: "The process whose specific outcome is the progression of the genitalia over time, from its formation to the mature structure." [GOC:jid] synonym: "genital development" EXACT [] is_a: GO:0048513 ! animal organ development is_a: GO:0048608 ! reproductive structure development relationship: part_of GO:0007548 ! sex differentiation [Term] id: GO:0048808 name: male genitalia morphogenesis namespace: biological_process def: "The process in which the anatomical structures of male genitalia are generated and organized." [GOC:ems, ISBN:0140512888] synonym: "male genital morphogenesis" RELATED [] is_a: GO:0035112 ! genitalia morphogenesis is_a: GO:0090598 ! male anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000079 ! male reproductive system relationship: part_of GO:0030539 ! male genitalia development relationship: results_in_morphogenesis_of UBERON:0000079 ! male reproductive system [Term] id: GO:0048812 name: neuron projection morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites." [GOC:mah] synonym: "neurite biosynthesis" NARROW [] synonym: "neurite formation" NARROW [] synonym: "neurite growth" NARROW [] synonym: "neurite morphogenesis" RELATED [GOC:dph, GOC:tb] is_a: GO:0120039 ! plasma membrane bounded cell projection morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of GO:0043005 ! neuron projection relationship: part_of GO:0031175 ! neuron projection development relationship: results_in_morphogenesis_of GO:0043005 ! neuron projection [Term] id: GO:0048821 name: erythrocyte development namespace: biological_process def: "The process whose specific outcome is the progression of an erythrocyte over time, from its formation to the mature structure." [GOC:devbiol] synonym: "RBC development" EXACT [CL:0000232] synonym: "red blood cell development" EXACT [CL:0000232] is_a: GO:0061515 ! myeloid cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000232 ! erythrocyte relationship: part_of GO:0030218 ! erythrocyte differentiation relationship: results_in_development_of CL:0000232 ! erythrocyte [Term] id: GO:0048822 name: enucleate erythrocyte development namespace: biological_process def: "The process aimed at the progression of an enucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:devbiol] synonym: "enucleate RBC development" EXACT [CL:0000232] synonym: "enucleate red blood cell development" EXACT [CL:0000232] is_a: GO:0048821 ! erythrocyte development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000595 ! enucleate erythrocyte relationship: part_of GO:0043353 ! enucleate erythrocyte differentiation relationship: results_in_development_of CL:0000595 ! enucleate erythrocyte [Term] id: GO:0048823 name: nucleate erythrocyte development namespace: biological_process def: "The process aimed at the progression of a nucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:devbiol] synonym: "nucleate RBC development" EXACT [CL:0000232] synonym: "nucleate red blood cell development" EXACT [CL:0000232] is_a: GO:0048821 ! erythrocyte development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000562 ! nucleate erythrocyte relationship: part_of GO:0043363 ! nucleate erythrocyte differentiation relationship: results_in_development_of CL:0000562 ! nucleate erythrocyte [Term] id: GO:0048844 name: artery morphogenesis namespace: biological_process def: "The process in which the anatomical structures of arterial blood vessels are generated and organized. Arteries are blood vessels that transport blood from the heart to the body and its organs." [GOC:dsf, PMID:16740480] synonym: "arterial morphogenesis" EXACT [] synonym: "arteriogenesis" EXACT [GOC:mtg_heart] is_a: GO:0048514 ! blood vessel morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001637 ! artery relationship: part_of GO:0060840 ! artery development relationship: results_in_morphogenesis_of UBERON:0001637 ! artery [Term] id: GO:0048845 name: venous blood vessel morphogenesis namespace: biological_process def: "The process in which the anatomical structures of venous blood vessels are generated and organized. Veins are blood vessels that transport blood from the body and its organs to the heart." [GOC:dsf, PMID:16740480] synonym: "vein morphogenesis" BROAD [] synonym: "venous morphogenesis" EXACT [] is_a: GO:0048514 ! blood vessel morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001638 ! vein relationship: part_of GO:0060841 ! venous blood vessel development relationship: results_in_morphogenesis_of UBERON:0001638 ! vein [Term] id: GO:0048854 name: brain morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the brain are generated and organized. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)." [GOC:dgh, GOC:jid] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000955 ! brain relationship: part_of GO:0007420 ! brain development relationship: results_in_morphogenesis_of UBERON:0000955 ! brain [Term] id: GO:0048856 name: anatomical structure development namespace: biological_process def: "The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." [GO_REF:0000021] subset: gocheck_do_not_annotate subset: goslim_chembl subset: goslim_generic subset: goslim_plant synonym: "development of an anatomical structure" EXACT [] is_a: GO:0032502 ! developmental process intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of UBERON:0000061 ! anatomical structure relationship: results_in_development_of UBERON:0000061 ! anatomical structure property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI [Term] id: GO:0048857 name: neural nucleus development namespace: biological_process def: "The biological process whose specific outcome is the progression of a neural nucleus from its initial condition to its mature state. A neural nucleus is an anatomical structure consisting of a discrete aggregate of neuronal soma." [GO_REF:0000021] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000125 ! neural nucleus relationship: results_in_development_of UBERON:0000125 ! neural nucleus [Term] id: GO:0048858 name: cell projection morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a cell projection are generated and organized." [GO_REF:0000021] is_a: GO:0030030 ! cell projection organization is_a: GO:0032989 ! cellular anatomical entity morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of GO:0042995 ! cell projection relationship: part_of GO:0000902 ! cell morphogenesis relationship: results_in_morphogenesis_of GO:0042995 ! cell projection [Term] id: GO:0048859 name: formation of anatomical boundary namespace: biological_process def: "The process in which the limits of an anatomical structure are generated. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." [GO_REF:0000021] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0007651 ! anatomical junction relationship: results_in_formation_of_anatomical_entity UBERON:0007651 ! anatomical junction [Term] id: GO:0048863 name: stem cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [CL:0000034, GOC:isa_complete] xref: Wikipedia:Stem_cell_differentiation is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000034 ! stem cell relationship: results_in_acquisition_of_features_of CL:0000034 ! stem cell property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0048864 name: stem cell development namespace: biological_process def: "The process whose specific outcome is the progression of the stem cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to its specific fate." [CL:0000034, GOC:isa_complete] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000034 ! stem cell relationship: part_of GO:0048863 ! stem cell differentiation relationship: results_in_development_of CL:0000034 ! stem cell [Term] id: GO:0048869 name: cellular developmental process namespace: biological_process def: "A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition." [GOC:isa_complete] is_a: GO:0009987 ! cellular process is_a: GO:0032502 ! developmental process [Term] id: GO:0048870 name: cell motility namespace: biological_process def: "Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another." [GOC:dgh, GOC:dph, GOC:isa_complete, GOC:mlg] subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_prokaryote synonym: "cell locomotion" EXACT [] synonym: "cell movement" RELATED [] synonym: "movement of a cell" EXACT [] is_a: GO:0009987 ! cellular process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19809" xsd:anyURI [Term] id: GO:0048871 name: multicellular organismal-level homeostasis namespace: biological_process def: "Any process involved in the maintenance of an internal steady state at the level of the multicellular organism." [GOC:isa_complete] is_a: GO:0032501 ! multicellular organismal process is_a: GO:0042592 ! homeostatic process [Term] id: GO:0048872 name: homeostasis of number of cells namespace: biological_process def: "Any biological process involved in the maintenance of the steady-state number of cells within a population of cells." [GOC:isa_complete] synonym: "cell population homeostasis" EXACT [] synonym: "homeostasis of cell number" EXACT [GOC:dph] is_a: GO:0048871 ! multicellular organismal-level homeostasis property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24218" xsd:anyURI [Term] id: GO:0048880 name: sensory system development namespace: biological_process def: "The process whose specific outcome is the progression of a sensory system over time from its formation to the mature structure." [GOC:dgh] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001032 ! sensory system relationship: results_in_development_of UBERON:0001032 ! sensory system [Term] id: GO:0048934 name: peripheral nervous system neuron differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the peripheral nervous system." [GOC:dgh] is_a: GO:0030182 ! neuron differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:2000032 ! peripheral nervous system neuron relationship: part_of GO:0007422 ! peripheral nervous system development relationship: results_in_acquisition_of_features_of CL:2000032 ! peripheral nervous system neuron [Term] id: GO:0048935 name: peripheral nervous system neuron development namespace: biological_process def: "The process whose specific outcome is the progression of a neuron whose cell body is located in the peripheral nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron." [GOC:dgh] is_a: GO:0048666 ! neuron development intersection_of: GO:0048468 ! cell development intersection_of: results_in_development_of CL:2000032 ! peripheral nervous system neuron relationship: part_of GO:0048934 ! peripheral nervous system neuron differentiation relationship: results_in_development_of CL:2000032 ! peripheral nervous system neuron [Term] id: GO:0050000 name: chromosome localization namespace: biological_process def: "Any process in which a chromosome is transported to, or maintained in, a specific location." [GOC:ai] synonym: "chromosome localisation" EXACT [GOC:mah] synonym: "establishment and maintenance of chromosome localization" EXACT [] synonym: "establishment and maintenance of chromosome position" EXACT [] is_a: GO:0051640 ! organelle localization intersection_of: GO:0051179 ! localization intersection_of: has_primary_input GO:0005694 ! chromosome relationship: has_primary_input GO:0005694 ! chromosome [Term] id: GO:0050432 name: catecholamine secretion namespace: biological_process def: "The regulated release of catecholamines by a cell. The catecholamines are a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." [GOC:ai, GOC:ef] is_a: GO:0032940 ! secretion by cell is_a: GO:0051937 ! catecholamine transport intersection_of: GO:0046903 ! secretion intersection_of: has_primary_input CHEBI:33567 ! catecholamine [Term] id: GO:0050433 name: regulation of catecholamine secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of catecholamines." [GOC:ai] is_a: GO:0051952 ! regulation of amine transport is_a: GO:1903530 ! regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0050432 ! catecholamine secretion relationship: regulates GO:0050432 ! catecholamine secretion [Term] id: GO:0050657 name: nucleic acid transport namespace: biological_process def: "The directed movement of nucleic acids, single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai, ISBN:0198506732] is_a: GO:0015931 ! nucleobase-containing compound transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:33696 ! nucleic acid relationship: has_primary_input CHEBI:33696 ! nucleic acid [Term] id: GO:0050658 name: RNA transport namespace: biological_process def: "The directed movement of RNA, ribonucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] is_a: GO:0050657 ! nucleic acid transport is_a: GO:0051236 ! establishment of RNA localization intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:33697 ! ribonucleic acid relationship: has_primary_input CHEBI:33697 ! ribonucleic acid [Term] id: GO:0050670 name: regulation of lymphocyte proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of lymphocyte proliferation." [GOC:ai] is_a: GO:0032944 ! regulation of mononuclear cell proliferation is_a: GO:0051249 ! regulation of lymphocyte activation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0046651 ! lymphocyte proliferation relationship: regulates GO:0046651 ! lymphocyte proliferation [Term] id: GO:0050671 name: positive regulation of lymphocyte proliferation namespace: biological_process def: "Any process that activates or increases the rate or extent of lymphocyte proliferation." [GOC:ai] synonym: "activation of lymphocyte proliferation" NARROW [] synonym: "stimulation of lymphocyte proliferation" NARROW [] synonym: "up regulation of lymphocyte proliferation" EXACT [] synonym: "up-regulation of lymphocyte proliferation" EXACT [] synonym: "upregulation of lymphocyte proliferation" EXACT [] is_a: GO:0032946 ! positive regulation of mononuclear cell proliferation is_a: GO:0050670 ! regulation of lymphocyte proliferation is_a: GO:0051251 ! positive regulation of lymphocyte activation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0046651 ! lymphocyte proliferation relationship: positively_regulates GO:0046651 ! lymphocyte proliferation [Term] id: GO:0050672 name: negative regulation of lymphocyte proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of lymphocyte proliferation." [GOC:ai] synonym: "down regulation of lymphocyte proliferation" EXACT [] synonym: "down-regulation of lymphocyte proliferation" EXACT [] synonym: "downregulation of lymphocyte proliferation" EXACT [] synonym: "inhibition of lymphocyte proliferation" NARROW [] is_a: GO:0032945 ! negative regulation of mononuclear cell proliferation is_a: GO:0050670 ! regulation of lymphocyte proliferation is_a: GO:0051250 ! negative regulation of lymphocyte activation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0046651 ! lymphocyte proliferation relationship: negatively_regulates GO:0046651 ! lymphocyte proliferation [Term] id: GO:0050673 name: epithelial cell proliferation namespace: biological_process def: "The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population. Epithelial cells make up the epithelium, the covering of internal and external surfaces of the body, including the lining of vessels and other small cavities. It consists of cells joined by small amounts of cementing substances." [ISBN:0721662544] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000066 ! epithelial cell relationship: acts_on_population_of CL:0000066 ! epithelial cell [Term] id: GO:0050678 name: regulation of epithelial cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of epithelial cell proliferation." [GOC:ai] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0050673 ! epithelial cell proliferation relationship: regulates GO:0050673 ! epithelial cell proliferation [Term] id: GO:0050679 name: positive regulation of epithelial cell proliferation namespace: biological_process def: "Any process that activates or increases the rate or extent of epithelial cell proliferation." [GOC:ai] synonym: "activation of epithelial cell proliferation" NARROW [] synonym: "stimulation of epithelial cell proliferation" NARROW [] synonym: "up regulation of epithelial cell proliferation" EXACT [] synonym: "up-regulation of epithelial cell proliferation" EXACT [] synonym: "upregulation of epithelial cell proliferation" EXACT [] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0050678 ! regulation of epithelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0050673 ! epithelial cell proliferation relationship: positively_regulates GO:0050673 ! epithelial cell proliferation [Term] id: GO:0050680 name: negative regulation of epithelial cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation." [GOC:ai] synonym: "down regulation of epithelial cell proliferation" EXACT [] synonym: "down-regulation of epithelial cell proliferation" EXACT [] synonym: "downregulation of epithelial cell proliferation" EXACT [] synonym: "inhibition of epithelial cell proliferation" NARROW [] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0050678 ! regulation of epithelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0050673 ! epithelial cell proliferation relationship: negatively_regulates GO:0050673 ! epithelial cell proliferation [Term] id: GO:0050708 name: regulation of protein secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell." [GOC:ai] is_a: GO:0051223 ! regulation of protein transport is_a: GO:1903530 ! regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0009306 ! protein secretion relationship: regulates GO:0009306 ! protein secretion [Term] id: GO:0050709 name: negative regulation of protein secretion namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell." [GOC:ai] synonym: "down regulation of protein secretion" EXACT [] synonym: "down-regulation of protein secretion" EXACT [] synonym: "downregulation of protein secretion" EXACT [] synonym: "inhibition of protein secretion" NARROW [] is_a: GO:0050708 ! regulation of protein secretion is_a: GO:0051224 ! negative regulation of protein transport is_a: GO:1903531 ! negative regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0009306 ! protein secretion relationship: negatively_regulates GO:0009306 ! protein secretion [Term] id: GO:0050714 name: positive regulation of protein secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell." [GOC:ai] synonym: "activation of protein secretion" NARROW [] synonym: "stimulation of protein secretion" NARROW [] synonym: "up regulation of protein secretion" EXACT [] synonym: "up-regulation of protein secretion" EXACT [] synonym: "upregulation of protein secretion" EXACT [] is_a: GO:0050708 ! regulation of protein secretion is_a: GO:0051222 ! positive regulation of protein transport is_a: GO:1903532 ! positive regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0009306 ! protein secretion relationship: positively_regulates GO:0009306 ! protein secretion [Term] id: GO:0050727 name: regulation of inflammatory response namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents." [GOC:ai] is_a: GO:0031347 ! regulation of defense response is_a: GO:0032101 ! regulation of response to external stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006954 ! inflammatory response relationship: regulates GO:0006954 ! inflammatory response [Term] id: GO:0050728 name: negative regulation of inflammatory response namespace: biological_process alt_id: GO:0030236 def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response." [GOC:ai] synonym: "anti-inflammatory response" EXACT [] synonym: "down regulation of inflammatory response" EXACT [] synonym: "down-regulation of inflammatory response" EXACT [] synonym: "downregulation of inflammatory response" EXACT [] synonym: "inhibition of inflammatory response" NARROW [] is_a: GO:0031348 ! negative regulation of defense response is_a: GO:0032102 ! negative regulation of response to external stimulus is_a: GO:0050727 ! regulation of inflammatory response intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006954 ! inflammatory response relationship: negatively_regulates GO:0006954 ! inflammatory response [Term] id: GO:0050729 name: positive regulation of inflammatory response namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the inflammatory response." [GOC:ai] synonym: "activation of inflammatory response" NARROW [] synonym: "stimulation of inflammatory response" NARROW [] synonym: "up regulation of inflammatory response" EXACT [] synonym: "up-regulation of inflammatory response" EXACT [] synonym: "upregulation of inflammatory response" EXACT [] is_a: GO:0031349 ! positive regulation of defense response is_a: GO:0032103 ! positive regulation of response to external stimulus is_a: GO:0050727 ! regulation of inflammatory response intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006954 ! inflammatory response relationship: positively_regulates GO:0006954 ! inflammatory response [Term] id: GO:0050764 name: regulation of phagocytosis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of phagocytosis, the process in which phagocytes engulf external particulate material." [GOC:ai] is_a: GO:0030100 ! regulation of endocytosis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006909 ! phagocytosis relationship: regulates GO:0006909 ! phagocytosis property_value: RO:0002161 NCBITaxon:147537 [Term] id: GO:0050765 name: negative regulation of phagocytosis namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of phagocytosis." [GOC:ai] synonym: "down regulation of phagocytosis" EXACT [] synonym: "down-regulation of phagocytosis" EXACT [] synonym: "downregulation of phagocytosis" EXACT [] synonym: "inhibition of phagocytosis" NARROW [] is_a: GO:0045806 ! negative regulation of endocytosis is_a: GO:0050764 ! regulation of phagocytosis intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006909 ! phagocytosis relationship: negatively_regulates GO:0006909 ! phagocytosis [Term] id: GO:0050766 name: positive regulation of phagocytosis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of phagocytosis." [GOC:ai] synonym: "activation of phagocytosis" NARROW [] synonym: "stimulation of phagocytosis" NARROW [] synonym: "up regulation of phagocytosis" EXACT [] synonym: "up-regulation of phagocytosis" EXACT [] synonym: "upregulation of phagocytosis" EXACT [] is_a: GO:0045807 ! positive regulation of endocytosis is_a: GO:0050764 ! regulation of phagocytosis intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006909 ! phagocytosis relationship: positively_regulates GO:0006909 ! phagocytosis [Term] id: GO:0050767 name: regulation of neurogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of neurogenesis, the generation of cells in the nervous system." [GOC:ai] is_a: GO:0051960 ! regulation of nervous system development is_a: GO:0060284 ! regulation of cell development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0022008 ! neurogenesis relationship: regulates GO:0022008 ! neurogenesis [Term] id: GO:0050768 name: negative regulation of neurogenesis namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system." [GOC:ai] synonym: "down regulation of neurogenesis" EXACT [] synonym: "down-regulation of neurogenesis" EXACT [] synonym: "downregulation of neurogenesis" EXACT [] synonym: "inhibition of neurogenesis" NARROW [] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0050767 ! regulation of neurogenesis is_a: GO:0051961 ! negative regulation of nervous system development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0022008 ! neurogenesis relationship: negatively_regulates GO:0022008 ! neurogenesis [Term] id: GO:0050769 name: positive regulation of neurogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system." [GOC:ai] synonym: "activation of neurogenesis" NARROW [] synonym: "stimulation of neurogenesis" NARROW [] synonym: "up regulation of neurogenesis" EXACT [] synonym: "up-regulation of neurogenesis" EXACT [] synonym: "upregulation of neurogenesis" EXACT [] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0050767 ! regulation of neurogenesis is_a: GO:0051962 ! positive regulation of nervous system development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0022008 ! neurogenesis relationship: positively_regulates GO:0022008 ! neurogenesis [Term] id: GO:0050776 name: regulation of immune response namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus." [GOC:ai] is_a: GO:0002682 ! regulation of immune system process is_a: GO:0048583 ! regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006955 ! immune response relationship: regulates GO:0006955 ! immune response [Term] id: GO:0050777 name: negative regulation of immune response namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus." [GOC:ai] synonym: "down regulation of immune response" EXACT [] synonym: "down-regulation of immune response" EXACT [] synonym: "downregulation of immune response" EXACT [] synonym: "inhibition of immune response" NARROW [] is_a: GO:0002683 ! negative regulation of immune system process is_a: GO:0048585 ! negative regulation of response to stimulus is_a: GO:0050776 ! regulation of immune response intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006955 ! immune response relationship: negatively_regulates GO:0006955 ! immune response [Term] id: GO:0050778 name: positive regulation of immune response namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus." [GOC:ai] synonym: "stimulation of immune response" NARROW [] synonym: "up regulation of immune response" EXACT [] synonym: "up-regulation of immune response" EXACT [] synonym: "upregulation of immune response" EXACT [] is_a: GO:0002684 ! positive regulation of immune system process is_a: GO:0048584 ! positive regulation of response to stimulus is_a: GO:0050776 ! regulation of immune response intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006955 ! immune response relationship: positively_regulates GO:0006955 ! immune response [Term] id: GO:0050789 name: regulation of biological process namespace: biological_process alt_id: GO:0050791 def: "Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule." [GOC:ai, GOC:go_curators] subset: gocheck_do_not_annotate subset: goslim_candida subset: goslim_pir synonym: "regulation of physiological process" EXACT [] is_a: GO:0065007 ! biological regulation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0008150 ! biological process relationship: regulates GO:0008150 ! biological process [Term] id: GO:0050790 name: regulation of catalytic activity namespace: biological_process alt_id: GO:0048552 def: "Any process that modulates the activity of an enzyme." [GOC:ai, GOC:ebc, GOC:vw] subset: gocheck_do_not_annotate subset: goslim_chembl synonym: "regulation of enzyme activity" EXACT [] synonym: "regulation of metalloenzyme activity" NARROW [] is_a: GO:0065009 ! regulation of molecular function intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003824 ! catalytic activity relationship: regulates GO:0003824 ! catalytic activity [Term] id: GO:0050793 name: regulation of developmental process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." [GOC:go_curators] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0032502 ! developmental process relationship: regulates GO:0032502 ! developmental process [Term] id: GO:0050794 name: regulation of cellular process namespace: biological_process alt_id: GO:0051244 def: "Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:go_curators] subset: gocheck_do_not_annotate synonym: "regulation of cellular physiological process" EXACT [] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0009987 ! cellular process relationship: regulates GO:0009987 ! cellular process [Term] id: GO:0050795 name: regulation of behavior namespace: biological_process def: "Any process that modulates the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli." [GOC:go_curators, GOC:pr] synonym: "regulation of behaviour" EXACT [] is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007610 ! behavior relationship: regulates GO:0007610 ! behavior [Term] id: GO:0050796 name: regulation of insulin secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of insulin." [GOC:ai] is_a: GO:0050708 ! regulation of protein secretion is_a: GO:0090276 ! regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030073 ! insulin secretion relationship: regulates GO:0030073 ! insulin secretion [Term] id: GO:0050803 name: regulation of synapse structure or activity namespace: biological_process def: "Any process that modulates the physical form or the activity of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell)." [GOC:ai] relationship: in_taxon NCBITaxon:6072 {all_only="true"} ! Eumetazoa relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa [Term] id: GO:0050804 name: modulation of chemical synaptic transmission namespace: biological_process def: "Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission." [GOC:ai] subset: goslim_synapse synonym: "modulation of synaptic transmission" BROAD [] synonym: "regulation of chemical synaptic transmission" EXACT [] synonym: "regulation of synaptic transmission" EXACT [] is_a: GO:0099177 ! regulation of trans-synaptic signaling intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007268 ! chemical synaptic transmission relationship: regulates GO:0007268 ! chemical synaptic transmission [Term] id: GO:0050805 name: negative regulation of synaptic transmission namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse." [GOC:ai] synonym: "down regulation of synaptic transmission" EXACT [] synonym: "down-regulation of synaptic transmission" EXACT [] synonym: "downregulation of synaptic transmission" EXACT [] synonym: "inhibition of synaptic transmission" NARROW [] is_a: GO:0010648 ! negative regulation of cell communication is_a: GO:0023057 ! negative regulation of signaling is_a: GO:0050804 ! modulation of chemical synaptic transmission intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007268 ! chemical synaptic transmission relationship: negatively_regulates GO:0007268 ! chemical synaptic transmission [Term] id: GO:0050806 name: positive regulation of synaptic transmission namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse." [GOC:ai] synonym: "activation of synaptic transmission" NARROW [] synonym: "stimulation of synaptic transmission" NARROW [] synonym: "up regulation of synaptic transmission" EXACT [] synonym: "up-regulation of synaptic transmission" EXACT [] synonym: "upregulation of synaptic transmission" EXACT [] is_a: GO:0010647 ! positive regulation of cell communication is_a: GO:0023056 ! positive regulation of signaling is_a: GO:0050804 ! modulation of chemical synaptic transmission intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007268 ! chemical synaptic transmission relationship: positively_regulates GO:0007268 ! chemical synaptic transmission [Term] id: GO:0050807 name: regulation of synapse organization namespace: biological_process def: "Any process that modulates the physical form of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell)." [GOC:ai, GOC:dph, GOC:tb] subset: goslim_synapse synonym: "regulation of synapse organisation" EXACT [GOC:mah] synonym: "regulation of synapse organization and biogenesis" RELATED [GOC:mah] synonym: "regulation of synapse structure" EXACT [] is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0050808 ! synapse organization relationship: part_of GO:0050803 ! regulation of synapse structure or activity relationship: regulates GO:0050808 ! synapse organization [Term] id: GO:0050808 name: synapse organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell)." [GOC:ai, GOC:pr] subset: goslim_drosophila subset: goslim_synapse synonym: "synapse development" RELATED [GOC:aruk] synonym: "synapse morphogenesis" RELATED [GOC:BHF] synonym: "synapse organisation" EXACT [] synonym: "synapse organization and biogenesis" RELATED [GOC:mah] is_a: GO:0034330 ! cell junction organization intersection_of: GO:0009987 ! cellular process intersection_of: results_in_organization_of GO:0045202 ! synapse relationship: results_in_organization_of GO:0045202 ! synapse [Term] id: GO:0050810 name: regulation of steroid biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus." [GOC:ai] synonym: "regulation of steroid anabolism" EXACT [] synonym: "regulation of steroid biosynthesis" EXACT [] synonym: "regulation of steroid formation" EXACT [] synonym: "regulation of steroid synthesis" EXACT [] synonym: "regulation of steroidogenesis" EXACT [] is_a: GO:0019218 ! regulation of steroid metabolic process is_a: GO:0046890 ! regulation of lipid biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006694 ! steroid biosynthetic process relationship: regulates GO:0006694 ! steroid biosynthetic process [Term] id: GO:0050832 name: defense response to fungus namespace: biological_process alt_id: GO:0009623 alt_id: GO:0009817 alt_id: GO:0042831 def: "Reactions triggered in response to the presence of a fungus that act to protect the cell or organism." [GOC:ai] synonym: "defence response to fungi" EXACT [] synonym: "defence response to fungus" EXACT [] synonym: "defense response to fungi" EXACT [] synonym: "defense response to fungus, incompatible interaction" NARROW [] synonym: "resistance response to pathogenic fungi" NARROW [] synonym: "resistance response to pathogenic fungus" NARROW [] synonym: "response to parasitic fungi" NARROW [] synonym: "response to parasitic fungus" NARROW [] is_a: GO:0009620 ! response to fungus is_a: GO:0098542 ! defense response to other organism intersection_of: GO:0006952 ! defense response intersection_of: has_primary_input NCBITaxon:4751 ! Fungi [Term] id: GO:0050863 name: regulation of T cell activation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of T cell activation." [GOC:ai] synonym: "regulation of T lymphocyte activation" EXACT [] synonym: "regulation of T-cell activation" EXACT [] synonym: "regulation of T-lymphocyte activation" EXACT [] is_a: GO:0051249 ! regulation of lymphocyte activation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0042110 ! T cell activation relationship: regulates GO:0042110 ! T cell activation [Term] id: GO:0050865 name: regulation of cell activation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand." [GOC:ai] is_a: GO:0050794 ! regulation of cellular process is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001775 ! cell activation relationship: regulates GO:0001775 ! cell activation [Term] id: GO:0050866 name: negative regulation of cell activation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell activation." [GOC:ai] synonym: "down regulation of cell activation" EXACT [] synonym: "down-regulation of cell activation" EXACT [] synonym: "downregulation of cell activation" EXACT [] synonym: "inhibition of cell activation" NARROW [] is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:0050865 ! regulation of cell activation is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001775 ! cell activation relationship: negatively_regulates GO:0001775 ! cell activation [Term] id: GO:0050867 name: positive regulation of cell activation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of activation." [GOC:ai] synonym: "activation of cell activation" NARROW [] synonym: "stimulation of cell activation" NARROW [] synonym: "up regulation of cell activation" EXACT [] synonym: "up-regulation of cell activation" EXACT [] synonym: "upregulation of cell activation" EXACT [] is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:0050865 ! regulation of cell activation is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001775 ! cell activation relationship: positively_regulates GO:0001775 ! cell activation [Term] id: GO:0050868 name: negative regulation of T cell activation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of T cell activation." [GOC:ai] synonym: "down regulation of T cell activation" EXACT [] synonym: "down-regulation of T cell activation" EXACT [] synonym: "downregulation of T cell activation" EXACT [] synonym: "inhibition of T cell activation" NARROW [] synonym: "negative regulation of T lymphocyte activation" EXACT [] synonym: "negative regulation of T-cell activation" EXACT [] synonym: "negative regulation of T-lymphocyte activation" EXACT [] is_a: GO:0050863 ! regulation of T cell activation is_a: GO:0051250 ! negative regulation of lymphocyte activation is_a: GO:1903038 ! negative regulation of leukocyte cell-cell adhesion intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0042110 ! T cell activation relationship: negatively_regulates GO:0042110 ! T cell activation [Term] id: GO:0050870 name: positive regulation of T cell activation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of T cell activation." [GOC:ai] synonym: "activation of T cell activation" NARROW [] synonym: "positive regulation of T lymphocyte activation" EXACT [] synonym: "positive regulation of T-cell activation" EXACT [] synonym: "positive regulation of T-lymphocyte activation" EXACT [] synonym: "stimulation of T cell activation" NARROW [] synonym: "up regulation of T cell activation" EXACT [] synonym: "up-regulation of T cell activation" EXACT [] synonym: "upregulation of T cell activation" EXACT [] is_a: GO:0050863 ! regulation of T cell activation is_a: GO:0051251 ! positive regulation of lymphocyte activation is_a: GO:1903039 ! positive regulation of leukocyte cell-cell adhesion intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0042110 ! T cell activation relationship: positively_regulates GO:0042110 ! T cell activation [Term] id: GO:0050877 name: nervous system process namespace: biological_process def: "A organ system process carried out by any of the organs or tissues of neurological system." [GOC:ai, GOC:mtg_cardio] subset: goslim_agr subset: goslim_chembl subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_pir synonym: "neurological system process" EXACT [] synonym: "neurophysiological process" EXACT [] synonym: "pan-neural process" RELATED [] is_a: GO:0003008 ! system process intersection_of: GO:0003008 ! system process intersection_of: has_participant UBERON:0001016 ! nervous system relationship: has_participant UBERON:0001016 ! nervous system relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/13824" xsd:anyURI [Term] id: GO:0050878 name: regulation of body fluid levels namespace: biological_process def: "Any process that modulates the levels of body fluids." [GOC:ai, GOC:dph, GOC:tb] subset: goslim_pir [Term] id: GO:0050879 name: multicellular organismal movement namespace: biological_process def: "Any physiological process involved in changing the position of a multicellular organism or an anatomical part of a multicellular organism." [GOC:dph, GOC:mtg_muscle, GOC:tb] subset: goslim_pir is_a: GO:0032501 ! multicellular organismal process [Term] id: GO:0050881 name: musculoskeletal movement namespace: biological_process def: "The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system." [GOC:dph] is_a: GO:0050879 ! multicellular organismal movement is_a: GO:0050905 ! neuromuscular process [Term] id: GO:0050886 name: endocrine process namespace: biological_process def: "The process that involves the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system." [ISBN:0721662544] subset: goslim_generic subset: goslim_pir synonym: "endocrine physiological process" EXACT [] synonym: "endocrine physiology" EXACT [] is_a: GO:0003008 ! system process [Term] id: GO:0050890 name: cognition namespace: biological_process def: "The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory." [ISBN:0721619908] subset: goslim_drosophila xref: Wikipedia:Cognition is_a: GO:0050877 ! nervous system process [Term] id: GO:0050896 name: response to stimulus namespace: biological_process alt_id: GO:0051869 def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism." [GOC:ai, GOC:bf] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_manually_annotate subset: goslim_agr subset: goslim_flybase_ribbon subset: goslim_mouse subset: goslim_pir subset: goslim_prokaryote synonym: "physiological response to stimulus" EXACT [] is_a: GO:0008150 ! biological process [Term] id: GO:0050900 name: leukocyte migration namespace: biological_process def: "The movement of a leukocyte within or between different tissues and organs of the body." [GOC:add, ISBN:0781735149, PMID:14680625, PMID:14708592, PMID:7507411, PMID:8600538] synonym: "immune cell migration" EXACT [] synonym: "immune cell trafficking" EXACT [] synonym: "leucocyte migration" EXACT [] synonym: "leucocyte trafficking" EXACT [] synonym: "leukocyte trafficking" EXACT [] is_a: GO:0002376 ! immune system process is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000738 ! leukocyte relationship: in_taxon NCBITaxon:7742 {all_only="true"} ! Vertebrata relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: results_in_movement_of CL:0000738 ! leukocyte [Term] id: GO:0050905 name: neuromuscular process namespace: biological_process def: "Any process pertaining to the functions of the nervous and muscular systems of an organism." [GOC:ai] synonym: "neuromotor process" EXACT [] synonym: "neuromuscular physiological process" EXACT [] is_a: GO:0050877 ! nervous system process [Term] id: GO:0050906 name: detection of stimulus involved in sensory perception namespace: biological_process def: "The series of events involved in sensory perception in which a sensory stimulus is received and converted into a molecular signal." [GOC:ai, GOC:dos, GOC:dph] synonym: "sensory detection of stimulus" EXACT [] synonym: "sensory perception, sensory transduction of stimulus" EXACT [] synonym: "sensory perception, stimulus detection" EXACT [] synonym: "sensory transduction" EXACT [] xref: Wikipedia:Transduction_(physiology) is_a: GO:0051606 ! detection of stimulus intersection_of: GO:0051606 ! detection of stimulus intersection_of: part_of GO:0007600 ! sensory perception relationship: part_of GO:0007600 ! sensory perception [Term] id: GO:0050907 name: detection of chemical stimulus involved in sensory perception namespace: biological_process def: "The series of events in which a chemical stimulus is received and converted into a molecular signal as part of sensory perception." [GOC:ai, GOC:dos] synonym: "sensory detection of chemical stimulus" EXACT [] synonym: "sensory detection of chemical stimulus during sensory perception" EXACT [] synonym: "sensory perception, sensory detection of chemical stimulus" EXACT [] synonym: "sensory perception, sensory transduction of chemical stimulus" EXACT [] synonym: "sensory transduction of chemical stimulus" EXACT [] synonym: "sensory transduction of chemical stimulus during sensory perception" EXACT [] is_a: GO:0009593 ! detection of chemical stimulus is_a: GO:0050906 ! detection of stimulus involved in sensory perception intersection_of: GO:0009593 ! detection of chemical stimulus intersection_of: part_of GO:0007600 ! sensory perception relationship: part_of GO:0007606 ! sensory perception of chemical stimulus [Term] id: GO:0050908 name: detection of light stimulus involved in visual perception namespace: biological_process def: "The series of events involved in visual perception in which a light stimulus is received and converted into a molecular signal." [GOC:ai, GOC:dos] synonym: "sensory detection of light during visual perception" EXACT [] synonym: "sensory detection of light stimulus during visual perception" EXACT [] synonym: "sensory transduction of light during visual perception" EXACT [] synonym: "sensory transduction of light stimulus during visual perception" EXACT [] synonym: "visual perception, detection of light stimulus" EXACT [] synonym: "visual perception, sensory transduction during perception of light" EXACT [] synonym: "visual perception, sensory transduction of light stimulus" EXACT [] is_a: GO:0009584 ! detection of visible light is_a: GO:0050962 ! detection of light stimulus involved in sensory perception intersection_of: GO:0009583 ! detection of light stimulus intersection_of: part_of GO:0007601 ! visual perception relationship: part_of GO:0007601 ! visual perception [Term] id: GO:0050931 name: pigment cell differentiation namespace: biological_process alt_id: GO:0043357 alt_id: GO:0043358 def: "The process in which a relatively unspecialized cell acquires the specialized features of a pigmented cell, such as a melanocyte." [GOC:dgh] comment: Note that the chromatophore mentioned here is distinct from the pigment bearing structure found in certain photosynthetic bacteria and cyanobacteria. It is also different from the plant chromoplast, which is also sometimes called a chromatophore. synonym: "chromatophore differentiation" EXACT [] synonym: "pigmented cell differentiation" EXACT [] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000147 ! pigment cell relationship: part_of GO:0048066 ! developmental pigmentation relationship: results_in_acquisition_of_features_of CL:0000147 ! pigment cell [Term] id: GO:0050932 name: regulation of pigment cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of pigmented cell differentiation." [GOC:ai] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0050931 ! pigment cell differentiation relationship: regulates GO:0050931 ! pigment cell differentiation [Term] id: GO:0050941 name: negative regulation of pigment cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of pigment cell differentiation." [GOC:ai] synonym: "down regulation of pigment cell differentiation" EXACT [] synonym: "down-regulation of pigment cell differentiation" EXACT [] synonym: "downregulation of pigment cell differentiation" EXACT [] synonym: "inhibition of pigment cell differentiation" NARROW [] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0048086 ! negative regulation of developmental pigmentation is_a: GO:0050932 ! regulation of pigment cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0050931 ! pigment cell differentiation relationship: negatively_regulates GO:0050931 ! pigment cell differentiation [Term] id: GO:0050942 name: positive regulation of pigment cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of pigment cell differentiation." [GOC:ai] synonym: "activation of pigment cell differentiation" NARROW [] synonym: "stimulation of pigment cell differentiation" NARROW [] synonym: "up regulation of pigment cell differentiation" EXACT [] synonym: "up-regulation of pigment cell differentiation" EXACT [] synonym: "upregulation of pigment cell differentiation" EXACT [] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0048087 ! positive regulation of developmental pigmentation is_a: GO:0050932 ! regulation of pigment cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0050931 ! pigment cell differentiation relationship: positively_regulates GO:0050931 ! pigment cell differentiation [Term] id: GO:0050952 name: sensory perception of electrical stimulus namespace: biological_process def: "The series of events required for an organism to receive a sensory electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." [GOC:ai] is_a: GO:0007600 ! sensory perception [Term] id: GO:0050953 name: sensory perception of light stimulus namespace: biological_process def: "The series of events required for an organism to receive a sensory light stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." [GOC:ai] is_a: GO:0007600 ! sensory perception [Term] id: GO:0050954 name: sensory perception of mechanical stimulus namespace: biological_process def: "The series of events required for an organism to receive a sensory mechanical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." [GOC:ai] synonym: "chemi-mechanical coupling" RELATED [] synonym: "mechanosensory perception" EXACT [] synonym: "perception of mechanical stimulus" EXACT [] is_a: GO:0007600 ! sensory perception [Term] id: GO:0050956 name: electroception namespace: biological_process def: "The series of events required for an organism to receive an electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. Many fish possess an electroception sense; for example, the electric eel uses low voltage pulses of electricity for navigation and prey location." [GOC:ai, PMID:10210663, Wikipedia:Electroreception] synonym: "electroception sense" EXACT [] synonym: "electroceptive sense" EXACT [] xref: Wikipedia:Electroreception is_a: GO:0050952 ! sensory perception of electrical stimulus [Term] id: GO:0050962 name: detection of light stimulus involved in sensory perception namespace: biological_process def: "The series of events in which a light stimulus is received by a cell and converted into a molecular signal as part of the sensory perception of light." [GOC:ai, GOC:dos] synonym: "sensory detection of light stimulus" EXACT [] synonym: "sensory detection of light stimulus during sensory perception" EXACT [] synonym: "sensory perception, sensory detection of light stimulus" EXACT [] synonym: "sensory perception, sensory transduction of light stimulus" EXACT [] synonym: "sensory transduction of light stimulus" EXACT [] synonym: "sensory transduction of light stimulus during sensory perception" EXACT [] is_a: GO:0009583 ! detection of light stimulus is_a: GO:0050906 ! detection of stimulus involved in sensory perception intersection_of: GO:0009583 ! detection of light stimulus intersection_of: part_of GO:0007600 ! sensory perception relationship: part_of GO:0050953 ! sensory perception of light stimulus [Term] id: GO:0050963 name: detection of electrical stimulus involved in sensory perception namespace: biological_process def: "The series of events in which an electrical stimulus is received by a cell and converted into a molecular signal as part of sensory perception." [GOC:ai, GOC:dos] synonym: "sensory detection of electrical stimulus" EXACT [] synonym: "sensory detection of electrical stimulus during sensory perception" EXACT [] synonym: "sensory perception, sensory detection of electrical stimulus" EXACT [] synonym: "sensory perception, sensory transduction of electrical stimulus" EXACT [] synonym: "sensory transduction of electrical stimulus" EXACT [] synonym: "sensory transduction of electrical stimulus during sensory perception" EXACT [] is_a: GO:0050906 ! detection of stimulus involved in sensory perception is_a: GO:0050981 ! detection of electrical stimulus intersection_of: GO:0050981 ! detection of electrical stimulus intersection_of: part_of GO:0007600 ! sensory perception relationship: part_of GO:0050952 ! sensory perception of electrical stimulus [Term] id: GO:0050964 name: detection of electrical stimulus involved in electroception namespace: biological_process def: "The series of events that contribute to electroception in which an electrical stimulus is received and converted into a molecular signal." [GOC:ai, GOC:dos] synonym: "detection of electrical stimulus during electroreception" RELATED [GOC:dph, GOC:tb] synonym: "electroception, detection of electrical stimulus" EXACT [] synonym: "electroception, sensory detection of electrical stimulus" EXACT [] synonym: "electroception, sensory transduction" EXACT [] synonym: "electroception, sensory transduction of electrical stimulus" EXACT [] synonym: "sensory detection of electrical stimulus during electroception" RELATED [] synonym: "sensory transduction of electrical stimulus during electroception" RELATED [] is_a: GO:0050963 ! detection of electrical stimulus involved in sensory perception intersection_of: GO:0050981 ! detection of electrical stimulus intersection_of: part_of GO:0050956 ! electroception relationship: part_of GO:0050956 ! electroception [Term] id: GO:0050967 name: detection of electrical stimulus involved in sensory perception of pain namespace: biological_process def: "The series of events that contribute to the perception of pain in which an electrical stimulus is received and converted into a molecular signal." [GOC:ai, GOC:dos, GOC:dph, GOC:tb] synonym: "detection of electrical stimulus during sensory perception of pain" RELATED [GOC:dph, GOC:tb] synonym: "perception of pain, detection of electrical stimulus" EXACT [] synonym: "perception of pain, sensory detection of electrical stimulus" EXACT [] synonym: "perception of pain, sensory transduction of electrical stimulus" EXACT [] synonym: "sensory detection of electrical stimulus during perception of pain" RELATED [] synonym: "sensory transduction of electrical stimulus during perception of pain" RELATED [] is_a: GO:0050963 ! detection of electrical stimulus involved in sensory perception is_a: GO:0062149 ! detection of stimulus involved in sensory perception of pain intersection_of: GO:0050981 ! detection of electrical stimulus intersection_of: part_of GO:0019233 ! sensory perception of pain [Term] id: GO:0050968 name: detection of chemical stimulus involved in sensory perception of pain namespace: biological_process def: "The series of events involved in the perception of pain in which a chemical stimulus is received and converted into a molecular signal." [GOC:ai] synonym: "chemical nociception" RELATED [GOC:pr] synonym: "perception of pain, detection of chemical stimulus" EXACT [] synonym: "perception of pain, sensory detection of chemical stimulus" EXACT [] synonym: "perception of pain, sensory transduction of chemical stimulus" EXACT [] synonym: "sensory detection of chemical stimulus during perception of pain" EXACT [] synonym: "sensory transduction of chemical stimulus during perception of pain" EXACT [] is_a: GO:0050907 ! detection of chemical stimulus involved in sensory perception is_a: GO:0062149 ! detection of stimulus involved in sensory perception of pain intersection_of: GO:0009593 ! detection of chemical stimulus intersection_of: part_of GO:0019233 ! sensory perception of pain [Term] id: GO:0050975 name: sensory perception of touch namespace: biological_process def: "The series of events required for an organism to receive a touch stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. The perception of touch in animals is mediated by mechanoreceptors in the skin and mucous membranes and is the sense by which contact with objects gives evidence as to certain of their qualities. Different types of touch can be perceived (for example, light, coarse, pressure and tickling) and the stimulus may be external or internal (e.g. the feeling of a full stomach)." [GOC:ai] synonym: "perception of touch" EXACT [] synonym: "tactile sense" EXACT [] synonym: "taction" EXACT [] synonym: "tactition" EXACT [] xref: Wikipedia:Touch is_a: GO:0050954 ! sensory perception of mechanical stimulus [Term] id: GO:0050981 name: detection of electrical stimulus namespace: biological_process def: "The series of events by which an electrical stimulus is received and converted into a molecular signal." [GOC:ai, GOC:dos] is_a: GO:0009582 ! detection of abiotic stimulus is_a: GO:0051602 ! response to electrical stimulus [Term] id: GO:0050994 name: regulation of lipid catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of lipids." [GOC:ai] synonym: "regulation of lipid breakdown" EXACT [] synonym: "regulation of lipid catabolism" EXACT [] synonym: "regulation of lipid degradation" EXACT [] is_a: GO:0009894 ! regulation of catabolic process is_a: GO:0019216 ! regulation of lipid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0016042 ! lipid catabolic process relationship: regulates GO:0016042 ! lipid catabolic process [Term] id: GO:0050995 name: negative regulation of lipid catabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids." [GOC:ai] synonym: "down regulation of lipid catabolic process" EXACT [] synonym: "down-regulation of lipid catabolic process" EXACT [] synonym: "downregulation of lipid catabolic process" EXACT [] synonym: "inhibition of lipid catabolic process" NARROW [] synonym: "negative regulation of lipid breakdown" EXACT [] synonym: "negative regulation of lipid catabolism" EXACT [] synonym: "negative regulation of lipid degradation" EXACT [] is_a: GO:0009895 ! negative regulation of catabolic process is_a: GO:0045833 ! negative regulation of lipid metabolic process is_a: GO:0050994 ! regulation of lipid catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0016042 ! lipid catabolic process relationship: negatively_regulates GO:0016042 ! lipid catabolic process [Term] id: GO:0050996 name: positive regulation of lipid catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids." [GOC:ai] synonym: "activation of lipid catabolic process" NARROW [] synonym: "positive regulation of lipid breakdown" EXACT [] synonym: "positive regulation of lipid catabolism" EXACT [] synonym: "positive regulation of lipid degradation" EXACT [] synonym: "stimulation of lipid catabolic process" NARROW [] synonym: "up regulation of lipid catabolic process" EXACT [] synonym: "up-regulation of lipid catabolic process" EXACT [] synonym: "upregulation of lipid catabolic process" EXACT [] is_a: GO:0009896 ! positive regulation of catabolic process is_a: GO:0045834 ! positive regulation of lipid metabolic process is_a: GO:0050994 ! regulation of lipid catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0016042 ! lipid catabolic process relationship: positively_regulates GO:0016042 ! lipid catabolic process [Term] id: GO:0051017 name: actin filament bundle assembly namespace: biological_process alt_id: GO:0045011 def: "The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness." [GOC:ai] synonym: "actin bundling activity" RELATED [] synonym: "actin cable assembly" RELATED [GOC:mah] synonym: "actin cable formation" RELATED [GOC:mah] is_a: GO:0022607 ! cellular component assembly is_a: GO:0061572 ! actin filament bundle organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0032432 ! actin filament bundle relationship: results_in_assembly_of GO:0032432 ! actin filament bundle [Term] id: GO:0051027 name: DNA transport namespace: biological_process def: "The directed movement of RNA, deoxyribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] is_a: GO:0050657 ! nucleic acid transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:16991 ! deoxyribonucleic acid relationship: has_primary_input CHEBI:16991 ! deoxyribonucleic acid [Term] id: GO:0051032 name: nucleic acid transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of nucleic acids from one side of a membrane to the other. Nucleic acids are single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information." [GOC:ai] is_a: GO:0015932 ! nucleobase-containing compound transmembrane transporter activity is_a: GO:0022884 ! macromolecule transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:33696 ! nucleic acid relationship: has_primary_input CHEBI:33696 ! nucleic acid relationship: part_of GO:0050657 ! nucleic acid transport [Term] id: GO:0051033 name: RNA transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of RNA, ribonucleic acid, from one side of a membrane to the other." [GOC:ai] xref: Reactome:R-HSA-203906 "Exportin complex translocates pre-miRNA to cytosol" is_a: GO:0051032 ! nucleic acid transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:33697 ! ribonucleic acid relationship: has_primary_input CHEBI:33697 ! ribonucleic acid relationship: part_of GO:0050658 ! RNA transport [Term] id: GO:0051035 name: DNA transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of DNA, deoxyribonucleic acid, from one side of a membrane to the other." [GOC:ai] is_a: GO:0051032 ! nucleic acid transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:16991 ! deoxyribonucleic acid relationship: has_primary_input CHEBI:16991 ! deoxyribonucleic acid relationship: part_of GO:0051027 ! DNA transport [Term] id: GO:0051046 name: regulation of secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue." [GOC:ai] is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0046903 ! secretion relationship: regulates GO:0046903 ! secretion [Term] id: GO:0051047 name: positive regulation of secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the controlled release of a substance from a cell or a tissue." [GOC:ai] synonym: "activation of secretion" NARROW [] synonym: "stimulation of secretion" NARROW [] synonym: "up regulation of secretion" EXACT [] synonym: "up-regulation of secretion" EXACT [] synonym: "upregulation of secretion" EXACT [] is_a: GO:0051046 ! regulation of secretion is_a: GO:0051050 ! positive regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0046903 ! secretion relationship: positively_regulates GO:0046903 ! secretion [Term] id: GO:0051048 name: negative regulation of secretion namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a substance from a cell or a tissue." [GOC:ai] synonym: "down regulation of secretion" EXACT [] synonym: "down-regulation of secretion" EXACT [] synonym: "downregulation of secretion" EXACT [] synonym: "inhibition of secretion" NARROW [] is_a: GO:0051046 ! regulation of secretion is_a: GO:0051051 ! negative regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0046903 ! secretion relationship: negatively_regulates GO:0046903 ! secretion [Term] id: GO:0051049 name: regulation of transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] subset: goslim_yeast is_a: GO:0032879 ! regulation of localization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006810 ! transport relationship: regulates GO:0006810 ! transport [Term] id: GO:0051050 name: positive regulation of transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "activation of transport" NARROW [] synonym: "stimulation of transport" NARROW [] synonym: "up regulation of transport" EXACT [] synonym: "up-regulation of transport" EXACT [] synonym: "upregulation of transport" EXACT [] is_a: GO:0048518 ! positive regulation of biological process is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006810 ! transport relationship: positively_regulates GO:0006810 ! transport [Term] id: GO:0051051 name: negative regulation of transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "down regulation of transport" EXACT [] synonym: "down-regulation of transport" EXACT [] synonym: "downregulation of transport" EXACT [] synonym: "inhibition of transport" NARROW [] is_a: GO:0048519 ! negative regulation of biological process is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006810 ! transport relationship: negatively_regulates GO:0006810 ! transport [Term] id: GO:0051052 name: regulation of DNA metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA." [GOC:ai] subset: goslim_yeast synonym: "regulation of DNA metabolism" EXACT [] is_a: GO:0019219 ! regulation of nucleobase-containing compound metabolic process is_a: GO:0060255 ! regulation of macromolecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006259 ! DNA metabolic process relationship: regulates GO:0006259 ! DNA metabolic process [Term] id: GO:0051053 name: negative regulation of DNA metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA." [GOC:ai] synonym: "down regulation of DNA metabolic process" EXACT [] synonym: "down-regulation of DNA metabolic process" EXACT [] synonym: "downregulation of DNA metabolic process" EXACT [] synonym: "inhibition of DNA metabolic process" NARROW [] synonym: "negative regulation of DNA metabolism" EXACT [] is_a: GO:0010605 ! negative regulation of macromolecule metabolic process is_a: GO:0045934 ! negative regulation of nucleobase-containing compound metabolic process is_a: GO:0051052 ! regulation of DNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006259 ! DNA metabolic process relationship: negatively_regulates GO:0006259 ! DNA metabolic process [Term] id: GO:0051054 name: positive regulation of DNA metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA." [GOC:ai] synonym: "activation of DNA metabolic process" NARROW [] synonym: "positive regulation of DNA metabolism" EXACT [] synonym: "stimulation of DNA metabolic process" NARROW [] synonym: "up regulation of DNA metabolic process" EXACT [] synonym: "up-regulation of DNA metabolic process" EXACT [] synonym: "upregulation of DNA metabolic process" EXACT [] is_a: GO:0010604 ! positive regulation of macromolecule metabolic process is_a: GO:0045935 ! positive regulation of nucleobase-containing compound metabolic process is_a: GO:0051052 ! regulation of DNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006259 ! DNA metabolic process relationship: positively_regulates GO:0006259 ! DNA metabolic process [Term] id: GO:0051055 name: negative regulation of lipid biosynthetic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids." [GOC:ai] synonym: "down regulation of lipid biosynthetic process" EXACT [] synonym: "down-regulation of lipid biosynthetic process" EXACT [] synonym: "downregulation of lipid biosynthetic process" EXACT [] synonym: "inhibition of lipid biosynthetic process" NARROW [] synonym: "negative regulation of lipid anabolism" EXACT [] synonym: "negative regulation of lipid biosynthesis" EXACT [] synonym: "negative regulation of lipid formation" EXACT [] synonym: "negative regulation of lipid synthesis" EXACT [] synonym: "negative regulation of lipogenesis" EXACT [GOC:sl] is_a: GO:0009890 ! negative regulation of biosynthetic process is_a: GO:0045833 ! negative regulation of lipid metabolic process is_a: GO:0046890 ! regulation of lipid biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0008610 ! lipid biosynthetic process relationship: negatively_regulates GO:0008610 ! lipid biosynthetic process [Term] id: GO:0051078 name: meiotic nuclear membrane disassembly namespace: biological_process def: "The cell cycle process in which the controlled breakdown of the nuclear membranes during meiotic cell division occurs." [GOC:bf] synonym: "meiotic nuclear envelope breakdown" RELATED [] synonym: "meiotic nuclear envelope catabolism" RELATED [] synonym: "meiotic nuclear envelope degradation" RELATED [] synonym: "meiotic nuclear envelope disassembly" RELATED [] is_a: GO:0051081 ! nuclear membrane disassembly is_a: GO:1903046 ! meiotic cell cycle process intersection_of: GO:0051081 ! nuclear membrane disassembly intersection_of: part_of GO:0051321 ! meiotic cell cycle [Term] id: GO:0051080 name: meiosis II nuclear membrane disassembly namespace: biological_process def: "The controlled breakdown of the nuclear membranes during the second division of meiosis." [GOC:bf] synonym: "meiosis II nuclear envelope breakdown" RELATED [] synonym: "meiosis II nuclear envelope catabolism" RELATED [] synonym: "meiosis II nuclear envelope degradation" RELATED [] synonym: "meiosis II nuclear envelope disassembly" RELATED [] is_a: GO:0051078 ! meiotic nuclear membrane disassembly intersection_of: GO:0051081 ! nuclear membrane disassembly intersection_of: part_of GO:0007135 ! meiosis II relationship: part_of GO:0007135 ! meiosis II [Term] id: GO:0051081 name: nuclear membrane disassembly namespace: biological_process def: "The controlled breakdown of the nuclear membranes, for example during cellular division." [GOC:ai] synonym: "nuclear envelope breakdown" RELATED [] synonym: "nuclear envelope catabolism" RELATED [] synonym: "nuclear envelope degradation" RELATED [] synonym: "nuclear envelope disassembly" RELATED [] is_a: GO:0030397 ! membrane disassembly is_a: GO:0071763 ! nuclear membrane organization intersection_of: GO:0022411 ! cellular component disassembly intersection_of: results_in_disassembly_of GO:0031965 ! nuclear membrane relationship: results_in_disassembly_of GO:0031965 ! nuclear membrane [Term] id: GO:0051093 name: negative regulation of developmental process namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." [GOC:ai] synonym: "down regulation of developmental process" EXACT [] synonym: "down-regulation of developmental process" EXACT [] synonym: "downregulation of developmental process" EXACT [] synonym: "inhibition of developmental process" NARROW [] is_a: GO:0048519 ! negative regulation of biological process is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0032502 ! developmental process relationship: negatively_regulates GO:0032502 ! developmental process [Term] id: GO:0051094 name: positive regulation of developmental process namespace: biological_process def: "Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." [GOC:ai] synonym: "activation of developmental process" NARROW [] synonym: "stimulation of developmental process" NARROW [] synonym: "up regulation of developmental process" EXACT [] synonym: "up-regulation of developmental process" EXACT [] synonym: "upregulation of developmental process" EXACT [] is_a: GO:0048518 ! positive regulation of biological process is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0032502 ! developmental process relationship: positively_regulates GO:0032502 ! developmental process [Term] id: GO:0051119 name: sugar transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of a sugar from one side of a membrane to the other. A sugar is any member of a class of sweet, water-soluble, crystallizable carbohydrates, which are the monosaccharides and smaller oligosaccharides." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] synonym: "sugar/polyol channel activity" NARROW [] xref: Reactome:R-HSA-428779 "GLUT7 and GLUT11 transport glucose and fructose" xref: Reactome:R-HSA-8875902 "SLC45A3 transports Glc from extracellular region to cytosol" xref: Reactome:R-HSA-8876319 "SLC50A1 transports Glc from cytosol to extracellular region" is_a: GO:0015144 ! carbohydrate transmembrane transporter activity [Term] id: GO:0051128 name: regulation of cellular component organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." [GOC:ai] synonym: "regulation of cell organisation" RELATED [GOC:mah] synonym: "regulation of cell organization" RELATED [GOC:mah] synonym: "regulation of cellular component organisation" EXACT [] synonym: "regulation of cellular component organization and biogenesis" RELATED [GOC:mah] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0016043 ! cellular component organization relationship: regulates GO:0016043 ! cellular component organization [Term] id: GO:0051129 name: negative regulation of cellular component organization namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." [GOC:ai] synonym: "down regulation of cell organization" EXACT [] synonym: "down-regulation of cell organization" EXACT [] synonym: "downregulation of cell organization" EXACT [] synonym: "inhibition of cell organization" NARROW [] synonym: "negative regulation of cell organisation" RELATED [GOC:mah] synonym: "negative regulation of cellular component organization and biogenesis" RELATED [GOC:mah] is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0016043 ! cellular component organization relationship: negatively_regulates GO:0016043 ! cellular component organization [Term] id: GO:0051130 name: positive regulation of cellular component organization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." [GOC:ai] synonym: "activation of cell organization" NARROW [] synonym: "positive regulation of cell organisation" EXACT [] synonym: "positive regulation of cellular component organization and biogenesis" RELATED [GOC:mah] synonym: "stimulation of cell organization" NARROW [] synonym: "up regulation of cell organization" EXACT [] synonym: "up-regulation of cell organization" EXACT [] synonym: "upregulation of cell organization" EXACT [] is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0016043 ! cellular component organization relationship: positively_regulates GO:0016043 ! cellular component organization [Term] id: GO:0051145 name: smooth muscle cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary." [CL:0000192, GOC:ai] synonym: "nonstriated muscle cell differentiation" EXACT [] is_a: GO:0042692 ! muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000192 ! smooth muscle cell relationship: results_in_acquisition_of_features_of CL:0000192 ! smooth muscle cell [Term] id: GO:0051146 name: striated muscle cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a striated muscle cell; striated muscle fibers are divided by transverse bands into striations, and cardiac and voluntary muscle are types of striated muscle." [CL:0000737, GOC:ai] synonym: "voluntary muscle cell differentiation" NARROW [] is_a: GO:0042692 ! muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000737 ! striated muscle cell relationship: results_in_acquisition_of_features_of CL:0000737 ! striated muscle cell [Term] id: GO:0051147 name: regulation of muscle cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of muscle cell differentiation." [CL:0000187, GOC:ai] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0042692 ! muscle cell differentiation relationship: regulates GO:0042692 ! muscle cell differentiation [Term] id: GO:0051148 name: negative regulation of muscle cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of muscle cell differentiation." [CL:0000187, GOC:ai] synonym: "down regulation of muscle cell differentiation" EXACT [] synonym: "down-regulation of muscle cell differentiation" EXACT [] synonym: "downregulation of muscle cell differentiation" EXACT [] synonym: "inhibition of muscle cell differentiation" NARROW [] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0051147 ! regulation of muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0042692 ! muscle cell differentiation relationship: negatively_regulates GO:0042692 ! muscle cell differentiation [Term] id: GO:0051149 name: positive regulation of muscle cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of muscle cell differentiation." [CL:0000187, GOC:ai] synonym: "activation of muscle cell differentiation" NARROW [] synonym: "stimulation of muscle cell differentiation" NARROW [] synonym: "up regulation of muscle cell differentiation" EXACT [] synonym: "up-regulation of muscle cell differentiation" EXACT [] synonym: "upregulation of muscle cell differentiation" EXACT [] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0051147 ! regulation of muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0042692 ! muscle cell differentiation relationship: positively_regulates GO:0042692 ! muscle cell differentiation [Term] id: GO:0051150 name: regulation of smooth muscle cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of smooth muscle cell differentiation." [CL:0000192, GOC:ai] is_a: GO:0051147 ! regulation of muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0051145 ! smooth muscle cell differentiation relationship: regulates GO:0051145 ! smooth muscle cell differentiation [Term] id: GO:0051151 name: negative regulation of smooth muscle cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell differentiation." [CL:0000192, GOC:ai] synonym: "down regulation of smooth muscle cell differentiation" EXACT [] synonym: "down-regulation of smooth muscle cell differentiation" EXACT [] synonym: "downregulation of smooth muscle cell differentiation" EXACT [] synonym: "inhibition of smooth muscle cell differentiation" NARROW [] is_a: GO:0051148 ! negative regulation of muscle cell differentiation is_a: GO:0051150 ! regulation of smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0051145 ! smooth muscle cell differentiation relationship: negatively_regulates GO:0051145 ! smooth muscle cell differentiation [Term] id: GO:0051152 name: positive regulation of smooth muscle cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of smooth muscle cell differentiation." [CL:0000192, GOC:ai] synonym: "activation of smooth muscle cell differentiation" NARROW [] synonym: "stimulation of smooth muscle cell differentiation" NARROW [] synonym: "up regulation of smooth muscle cell differentiation" EXACT [] synonym: "up-regulation of smooth muscle cell differentiation" EXACT [] synonym: "upregulation of smooth muscle cell differentiation" EXACT [] is_a: GO:0051149 ! positive regulation of muscle cell differentiation is_a: GO:0051150 ! regulation of smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0051145 ! smooth muscle cell differentiation relationship: positively_regulates GO:0051145 ! smooth muscle cell differentiation [Term] id: GO:0051153 name: regulation of striated muscle cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of striated muscle cell differentiation." [CL:0000737, GOC:ai] is_a: GO:0051147 ! regulation of muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0051146 ! striated muscle cell differentiation relationship: regulates GO:0051146 ! striated muscle cell differentiation [Term] id: GO:0051154 name: negative regulation of striated muscle cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle cell differentiation." [CL:0000737, GOC:ai] synonym: "down regulation of striated muscle cell differentiation" EXACT [] synonym: "down-regulation of striated muscle cell differentiation" EXACT [] synonym: "downregulation of striated muscle cell differentiation" EXACT [] synonym: "inhibition of striated muscle cell differentiation" NARROW [] is_a: GO:0051148 ! negative regulation of muscle cell differentiation is_a: GO:0051153 ! regulation of striated muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0051146 ! striated muscle cell differentiation relationship: negatively_regulates GO:0051146 ! striated muscle cell differentiation [Term] id: GO:0051155 name: positive regulation of striated muscle cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of striated muscle cell differentiation." [CL:0000737, GOC:ai] synonym: "activation of striated muscle cell differentiation" NARROW [] synonym: "stimulation of striated muscle cell differentiation" NARROW [] synonym: "up regulation of striated muscle cell differentiation" EXACT [] synonym: "up-regulation of striated muscle cell differentiation" EXACT [] synonym: "upregulation of striated muscle cell differentiation" EXACT [] is_a: GO:0051149 ! positive regulation of muscle cell differentiation is_a: GO:0051153 ! regulation of striated muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0051146 ! striated muscle cell differentiation relationship: positively_regulates GO:0051146 ! striated muscle cell differentiation [Term] id: GO:0051169 name: nuclear transport namespace: biological_process def: "The directed movement of substances into, out of, or within the nucleus." [GOC:ai] subset: goslim_yeast synonym: "nucleus transport" EXACT [] xref: Wikipedia:Nuclear_transport is_a: GO:0046907 ! intracellular transport intersection_of: GO:0006810 ! transport intersection_of: occurs_in GO:0005622 ! intracellular anatomical structure intersection_of: results_in_transport_to_from_or_in GO:0005634 ! nucleus relationship: results_in_transport_to_from_or_in GO:0005634 ! nucleus [Term] id: GO:0051171 name: regulation of nitrogen compound metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds." [GOC:ai, GOC:tb] synonym: "regulation of nitrogen metabolic process" EXACT [GOC:tb] synonym: "regulation of nitrogen metabolism" EXACT [] is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006807 ! nitrogen compound metabolic process relationship: regulates GO:0006807 ! nitrogen compound metabolic process [Term] id: GO:0051172 name: negative regulation of nitrogen compound metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds." [GOC:ai, GOC:tb] synonym: "down regulation of nitrogen metabolic process" EXACT [] synonym: "down-regulation of nitrogen metabolic process" EXACT [] synonym: "downregulation of nitrogen metabolic process" EXACT [] synonym: "inhibition of nitrogen metabolic process" NARROW [] synonym: "negative regulation of nitrogen metabolic process" EXACT [GOC:tb] synonym: "negative regulation of nitrogen metabolism" EXACT [] is_a: GO:0009892 ! negative regulation of metabolic process is_a: GO:0051171 ! regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006807 ! nitrogen compound metabolic process relationship: negatively_regulates GO:0006807 ! nitrogen compound metabolic process [Term] id: GO:0051173 name: positive regulation of nitrogen compound metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds." [GOC:ai, GOC:tb] synonym: "activation of nitrogen metabolic process" NARROW [] synonym: "positive regulation of nitrogen metabolic process" EXACT [GOC:tb] synonym: "positive regulation of nitrogen metabolism" EXACT [] synonym: "stimulation of nitrogen metabolic process" NARROW [] synonym: "up regulation of nitrogen metabolic process" EXACT [] synonym: "up-regulation of nitrogen metabolic process" EXACT [] synonym: "upregulation of nitrogen metabolic process" EXACT [] is_a: GO:0009893 ! positive regulation of metabolic process is_a: GO:0051171 ! regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006807 ! nitrogen compound metabolic process relationship: positively_regulates GO:0006807 ! nitrogen compound metabolic process [Term] id: GO:0051174 name: regulation of phosphorus metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus." [GOC:ai] synonym: "regulation of phosphorus metabolism" EXACT [] is_a: GO:0031323 ! regulation of cellular metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006793 ! phosphorus metabolic process relationship: regulates GO:0006793 ! phosphorus metabolic process [Term] id: GO:0051175 name: negative regulation of sulfur metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur." [GOC:ai] synonym: "down regulation of sulfur metabolic process" EXACT [] synonym: "down-regulation of sulfur metabolic process" EXACT [] synonym: "downregulation of sulfur metabolic process" EXACT [] synonym: "inhibition of sulfur metabolic process" NARROW [] synonym: "negative regulation of sulfur metabolism" EXACT [] synonym: "negative regulation of sulphur metabolic process" EXACT [] synonym: "negative regulation of sulphur metabolism" EXACT [] is_a: GO:0031324 ! negative regulation of cellular metabolic process is_a: GO:0042762 ! regulation of sulfur metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006790 ! sulfur compound metabolic process relationship: negatively_regulates GO:0006790 ! sulfur compound metabolic process [Term] id: GO:0051176 name: positive regulation of sulfur metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur." [GOC:ai] synonym: "activation of sulfur metabolic process" NARROW [] synonym: "positive regulation of sulfur metabolism" EXACT [] synonym: "positive regulation of sulphur metabolic process" EXACT [] synonym: "positive regulation of sulphur metabolism" EXACT [] synonym: "stimulation of sulfur metabolic process" NARROW [] synonym: "up regulation of sulfur metabolic process" EXACT [] synonym: "up-regulation of sulfur metabolic process" EXACT [] synonym: "upregulation of sulfur metabolic process" EXACT [] is_a: GO:0031325 ! positive regulation of cellular metabolic process is_a: GO:0042762 ! regulation of sulfur metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006790 ! sulfur compound metabolic process relationship: positively_regulates GO:0006790 ! sulfur compound metabolic process [Term] id: GO:0051179 name: localization namespace: biological_process alt_id: GO:1902578 def: "Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation." [GOC:ai, GOC:dos] subset: goslim_pir synonym: "establishment and maintenance of cellular component location" NARROW [] synonym: "establishment and maintenance of localization" EXACT [] synonym: "establishment and maintenance of position" EXACT [] synonym: "establishment and maintenance of substance location" NARROW [] synonym: "establishment and maintenance of substrate location" NARROW [] synonym: "localisation" EXACT [GOC:mah] synonym: "single organism localization" RELATED [GOC:TermGenie] synonym: "single-organism localization" RELATED [] is_a: GO:0008150 ! biological process created_by: jl creation_date: 2013-12-18T13:51:04Z [Term] id: GO:0051216 name: cartilage development namespace: biological_process def: "The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." [GOC:cjm, PMID:23251424] synonym: "cartilage biogenesis" EXACT [] synonym: "cartilage biosynthesis" EXACT [] synonym: "cartilage element development" EXACT [] synonym: "cartilage formation" EXACT [] synonym: "cartilage organ development" EXACT [] synonym: "chondrogenesis" EXACT [] xref: Wikipedia:Chondrogenesis is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0007844 ! cartilage element relationship: part_of GO:0001501 ! skeletal system development relationship: part_of GO:0061448 ! connective tissue development relationship: results_in_development_of UBERON:0007844 ! cartilage element [Term] id: GO:0051222 name: positive regulation of protein transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "activation of protein transport" NARROW [] synonym: "stimulation of protein transport" NARROW [] synonym: "up regulation of protein transport" EXACT [] synonym: "up-regulation of protein transport" EXACT [] synonym: "upregulation of protein transport" EXACT [] is_a: GO:0051050 ! positive regulation of transport is_a: GO:0051223 ! regulation of protein transport is_a: GO:1903829 ! positive regulation of protein localization is_a: GO:1904951 ! positive regulation of establishment of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0015031 ! protein transport relationship: positively_regulates GO:0015031 ! protein transport [Term] id: GO:0051223 name: regulation of protein transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] is_a: GO:0051049 ! regulation of transport is_a: GO:0070201 ! regulation of establishment of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0015031 ! protein transport relationship: regulates GO:0015031 ! protein transport [Term] id: GO:0051224 name: negative regulation of protein transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "down regulation of protein transport" EXACT [] synonym: "down-regulation of protein transport" EXACT [] synonym: "downregulation of protein transport" EXACT [] synonym: "inhibition of protein transport" NARROW [] is_a: GO:0051051 ! negative regulation of transport is_a: GO:0051223 ! regulation of protein transport is_a: GO:1903828 ! negative regulation of protein localization is_a: GO:1904950 ! negative regulation of establishment of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0015031 ! protein transport relationship: negatively_regulates GO:0015031 ! protein transport [Term] id: GO:0051234 name: establishment of localization namespace: biological_process def: "Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation." [GOC:ai, GOC:dos] subset: gocheck_do_not_annotate subset: goslim_agr subset: goslim_flybase_ribbon subset: goslim_mouse subset: goslim_pir synonym: "establishment of localisation" EXACT [GOC:mah] is_a: GO:0051179 ! localization property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24200" xsd:anyURI [Term] id: GO:0051236 name: establishment of RNA localization namespace: biological_process def: "The directed movement of RNA to a specific location." [GOC:ai] synonym: "establishment of RNA localisation" EXACT [GOC:mah] synonym: "RNA positioning" EXACT [] synonym: "RNA recruitment" EXACT [] is_a: GO:0051234 ! establishment of localization relationship: part_of GO:0006403 ! RNA localization [Term] id: GO:0051239 name: regulation of multicellular organismal process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs." [GOC:ai, GOC:dph, GOC:tb] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0032501 ! multicellular organismal process relationship: regulates GO:0032501 ! multicellular organismal process [Term] id: GO:0051240 name: positive regulation of multicellular organismal process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs." [GOC:ai] synonym: "activation of multicellular organismal process" NARROW [] synonym: "stimulation of multicellular organismal process" NARROW [] synonym: "up regulation of multicellular organismal process" EXACT [] synonym: "up-regulation of multicellular organismal process" EXACT [] synonym: "upregulation of multicellular organismal process" EXACT [] is_a: GO:0048518 ! positive regulation of biological process is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0032501 ! multicellular organismal process relationship: positively_regulates GO:0032501 ! multicellular organismal process [Term] id: GO:0051241 name: negative regulation of multicellular organismal process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs." [GOC:ai] synonym: "down regulation of multicellular organismal process" EXACT [] synonym: "down-regulation of multicellular organismal process" EXACT [] synonym: "downregulation of multicellular organismal process" EXACT [] synonym: "inhibition of multicellular organismal process" NARROW [] is_a: GO:0048519 ! negative regulation of biological process is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0032501 ! multicellular organismal process relationship: negatively_regulates GO:0032501 ! multicellular organismal process [Term] id: GO:0051246 name: regulation of protein metabolic process namespace: biological_process alt_id: GO:0032268 def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein." [GOC:ai] synonym: "regulation of cellular protein metabolic process" RELATED [] synonym: "regulation of cellular protein metabolism" RELATED [] synonym: "regulation of protein metabolism" EXACT [] is_a: GO:0051171 ! regulation of nitrogen compound metabolic process is_a: GO:0080090 ! regulation of primary metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0019538 ! protein metabolic process relationship: regulates GO:0019538 ! protein metabolic process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23112" xsd:anyURI [Term] id: GO:0051247 name: positive regulation of protein metabolic process namespace: biological_process alt_id: GO:0032270 def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein." [GOC:ai] synonym: "activation of cellular protein metabolic process" NARROW [] synonym: "activation of protein metabolic process" NARROW [] synonym: "positive regulation of cellular protein metabolic process" EXACT [] synonym: "positive regulation of cellular protein metabolism" EXACT [] synonym: "positive regulation of protein metabolism" EXACT [] synonym: "stimulation of cellular protein metabolic process" NARROW [] synonym: "stimulation of protein metabolic process" NARROW [] synonym: "up regulation of cellular protein metabolic process" EXACT [] synonym: "up regulation of protein metabolic process" EXACT [] synonym: "up-regulation of cellular protein metabolic process" EXACT [] synonym: "up-regulation of protein metabolic process" EXACT [] synonym: "upregulation of cellular protein metabolic process" EXACT [] synonym: "upregulation of protein metabolic process" EXACT [] is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process is_a: GO:0051246 ! regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0019538 ! protein metabolic process relationship: positively_regulates GO:0019538 ! protein metabolic process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23112" xsd:anyURI [Term] id: GO:0051248 name: negative regulation of protein metabolic process namespace: biological_process alt_id: GO:0032269 def: "Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein." [GOC:ai] synonym: "down regulation of cellular protein metabolic process" EXACT [] synonym: "down regulation of protein metabolic process" EXACT [] synonym: "down-regulation of cellular protein metabolic process" EXACT [] synonym: "down-regulation of protein metabolic process" EXACT [] synonym: "downregulation of cellular protein metabolic process" EXACT [] synonym: "downregulation of protein metabolic process" EXACT [] synonym: "inhibition of cellular protein metabolic process" NARROW [] synonym: "inhibition of protein metabolic process" NARROW [] synonym: "negative regulation of cellular protein metabolic process" EXACT [] synonym: "negative regulation of cellular protein metabolism" EXACT [] synonym: "negative regulation of protein metabolism" EXACT [] is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process is_a: GO:0051246 ! regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0019538 ! protein metabolic process relationship: negatively_regulates GO:0019538 ! protein metabolic process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23112" xsd:anyURI [Term] id: GO:0051249 name: regulation of lymphocyte activation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of lymphocyte activation." [GOC:ai] is_a: GO:0002694 ! regulation of leukocyte activation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0046649 ! lymphocyte activation relationship: regulates GO:0046649 ! lymphocyte activation [Term] id: GO:0051250 name: negative regulation of lymphocyte activation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte activation." [GOC:ai] synonym: "down regulation of lymphocyte activation" EXACT [] synonym: "down-regulation of lymphocyte activation" EXACT [] synonym: "downregulation of lymphocyte activation" EXACT [] synonym: "inhibition of lymphocyte activation" NARROW [] is_a: GO:0002695 ! negative regulation of leukocyte activation is_a: GO:0051249 ! regulation of lymphocyte activation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0046649 ! lymphocyte activation relationship: negatively_regulates GO:0046649 ! lymphocyte activation [Term] id: GO:0051251 name: positive regulation of lymphocyte activation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of lymphocyte activation." [GOC:ai] synonym: "activation of lymphocyte activation" NARROW [] synonym: "stimulation of lymphocyte activation" NARROW [] synonym: "up regulation of lymphocyte activation" EXACT [] synonym: "up-regulation of lymphocyte activation" EXACT [] synonym: "upregulation of lymphocyte activation" EXACT [] is_a: GO:0002696 ! positive regulation of leukocyte activation is_a: GO:0051249 ! regulation of lymphocyte activation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0046649 ! lymphocyte activation relationship: positively_regulates GO:0046649 ! lymphocyte activation [Term] id: GO:0051252 name: regulation of RNA metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA." [GOC:ai] synonym: "regulation of RNA metabolism" EXACT [] is_a: GO:0019219 ! regulation of nucleobase-containing compound metabolic process is_a: GO:0060255 ! regulation of macromolecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0016070 ! RNA metabolic process relationship: regulates GO:0016070 ! RNA metabolic process [Term] id: GO:0051253 name: negative regulation of RNA metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA." [GOC:ai] synonym: "down regulation of RNA metabolic process" EXACT [] synonym: "down-regulation of RNA metabolic process" EXACT [] synonym: "downregulation of RNA metabolic process" EXACT [] synonym: "inhibition of RNA metabolic process" NARROW [] synonym: "negative regulation of RNA metabolism" EXACT [] is_a: GO:0010605 ! negative regulation of macromolecule metabolic process is_a: GO:0045934 ! negative regulation of nucleobase-containing compound metabolic process is_a: GO:0051252 ! regulation of RNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0016070 ! RNA metabolic process relationship: negatively_regulates GO:0016070 ! RNA metabolic process [Term] id: GO:0051254 name: positive regulation of RNA metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving RNA." [GOC:ai] synonym: "activation of RNA metabolic process" NARROW [] synonym: "positive regulation of RNA metabolism" EXACT [] synonym: "stimulation of RNA metabolic process" NARROW [] synonym: "up regulation of RNA metabolic process" EXACT [] synonym: "up-regulation of RNA metabolic process" EXACT [] synonym: "upregulation of RNA metabolic process" EXACT [] is_a: GO:0010604 ! positive regulation of macromolecule metabolic process is_a: GO:0045935 ! positive regulation of nucleobase-containing compound metabolic process is_a: GO:0051252 ! regulation of RNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0016070 ! RNA metabolic process relationship: positively_regulates GO:0016070 ! RNA metabolic process [Term] id: GO:0051258 name: protein polymerization namespace: biological_process def: "The process of creating protein polymers, compounds composed of a large number of component monomers; polymeric proteins may be made up of different or identical monomers. Polymerization occurs by the addition of extra monomers to an existing poly- or oligomeric protein." [GOC:ai] subset: goslim_pir synonym: "protein polymer biosynthesis" EXACT [] synonym: "protein polymer biosynthetic process" EXACT [] synonym: "protein polymer formation" EXACT [] is_a: GO:0065003 ! protein-containing complex assembly [Term] id: GO:0051261 name: protein depolymerization namespace: biological_process def: "The process in which protein polymers, compounds composed of a large number of component monomers, are broken down. Depolymerization occurs by the successive removal of monomers from an existing poly- or oligomeric protein." [GOC:ai] subset: goslim_pir synonym: "protein polymer breakdown" EXACT [] synonym: "protein polymer catabolic process" EXACT [] synonym: "protein polymer catabolism" EXACT [] synonym: "protein polymer degradation" EXACT [] is_a: GO:0032984 ! protein-containing complex disassembly [Term] id: GO:0051276 name: chromosome organization namespace: biological_process alt_id: GO:0006323 alt_id: GO:0007001 alt_id: GO:0051277 def: "A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome." [GOC:ai, GOC:dph, GOC:jl, GOC:mah] subset: goslim_chembl subset: goslim_drosophila subset: goslim_pir synonym: "chromosome organisation" EXACT [] synonym: "chromosome organization and biogenesis" RELATED [GOC:mah] synonym: "DNA condensation" EXACT [] synonym: "DNA packaging" NARROW [] synonym: "maintenance of genome integrity" RELATED [] synonym: "nuclear genome maintenance" RELATED [] is_a: GO:0006996 ! organelle organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0005694 ! chromosome relationship: results_in_organization_of GO:0005694 ! chromosome property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22811" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/4585" xsd:anyURI [Term] id: GO:0051301 name: cell division namespace: biological_process def: "The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells." [GOC:di, GOC:go_curators, GOC:pr] comment: Note that this term differs from 'cytokinesis ; GO:0000910' in that cytokinesis does not include nuclear division. subset: goslim_chembl subset: goslim_drosophila subset: goslim_pir xref: Wikipedia:Cell_division is_a: GO:0009987 ! cellular process [Term] id: GO:0051302 name: regulation of cell division namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells." [GOC:go_curators] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0051301 ! cell division relationship: regulates GO:0051301 ! cell division [Term] id: GO:0051303 name: establishment of chromosome localization namespace: biological_process def: "The directed movement of a chromosome to a specific location." [GOC:ai] synonym: "chromosome positioning" EXACT [] synonym: "establishment of chromosome localisation" EXACT [GOC:mah] is_a: GO:0050000 ! chromosome localization is_a: GO:0051649 ! establishment of localization in cell is_a: GO:0051656 ! establishment of organelle localization intersection_of: GO:0051234 ! establishment of localization intersection_of: has_primary_input GO:0005694 ! chromosome [Term] id: GO:0051321 name: meiotic cell cycle namespace: biological_process alt_id: GO:0007126 def: "Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions." [GOC:ai] comment: Note that this term should not be confused with 'GO:0140013 ; meiotic nuclear division'. 'GO:0051321 ; meiotic cell cycle represents the entire mitotic cell cycle, while 'GO:0140013 meiotic nuclear division' specifically represents the actual nuclear division step of the mitotic cell cycle. subset: goslim_drosophila subset: goslim_yeast synonym: "meiosis" RELATED [] xref: Wikipedia:Meiosis is_a: GO:0007049 ! cell cycle is_a: GO:0022414 ! reproductive process intersection_of: GO:0007049 ! cell cycle intersection_of: has_part GO:0140013 ! meiotic nuclear division relationship: has_part GO:0140013 ! meiotic nuclear division relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota relationship: part_of GO:0019953 ! sexual reproduction property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24599" xsd:anyURI [Term] id: GO:0051336 name: regulation of hydrolase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3." [GOC:ai] subset: gocheck_do_not_annotate synonym: "hydrolase regulator" EXACT [] is_a: GO:0050790 ! regulation of catalytic activity intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0016787 ! hydrolase activity relationship: regulates GO:0016787 ! hydrolase activity [Term] id: GO:0051338 name: regulation of transferase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2." [GOC:ai] comment: This term is useful for grouping, but is too general for manual annotation. Please use a child term instead. subset: gocheck_do_not_annotate subset: gocheck_do_not_manually_annotate synonym: "transferase regulator" EXACT [] is_a: GO:0050790 ! regulation of catalytic activity intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0016740 ! transferase activity relationship: regulates GO:0016740 ! transferase activity [Term] id: GO:0051345 name: positive regulation of hydrolase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds." [GOC:ai] subset: gocheck_do_not_annotate synonym: "activation of hydrolase activity" NARROW [] synonym: "hydrolase activator" EXACT [] synonym: "stimulation of hydrolase activity" NARROW [] synonym: "up regulation of hydrolase activity" EXACT [] synonym: "up-regulation of hydrolase activity" EXACT [] synonym: "upregulation of hydrolase activity" EXACT [] is_a: GO:0043085 ! positive regulation of catalytic activity is_a: GO:0051336 ! regulation of hydrolase activity intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0016787 ! hydrolase activity relationship: positively_regulates GO:0016787 ! hydrolase activity [Term] id: GO:0051346 name: negative regulation of hydrolase activity namespace: biological_process def: "Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds." [GOC:ai] subset: gocheck_do_not_annotate synonym: "down regulation of hydrolase activity" EXACT [] synonym: "down-regulation of hydrolase activity" EXACT [] synonym: "downregulation of hydrolase activity" EXACT [] synonym: "hydrolase inhibitor" EXACT [] synonym: "inhibition of hydrolase activity" NARROW [] is_a: GO:0043086 ! negative regulation of catalytic activity is_a: GO:0051336 ! regulation of hydrolase activity intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0016787 ! hydrolase activity relationship: negatively_regulates GO:0016787 ! hydrolase activity [Term] id: GO:0051347 name: positive regulation of transferase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor." [GOC:ai] comment: This term is useful for grouping, but is too general for manual annotation. Please use a child term instead. subset: gocheck_do_not_annotate subset: gocheck_do_not_manually_annotate synonym: "activation of transferase activity" NARROW [] synonym: "stimulation of transferase activity" NARROW [] synonym: "transferase activator" EXACT [] synonym: "up regulation of transferase activity" EXACT [] synonym: "up-regulation of transferase activity" EXACT [] synonym: "upregulation of transferase activity" EXACT [] is_a: GO:0043085 ! positive regulation of catalytic activity is_a: GO:0051338 ! regulation of transferase activity intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0016740 ! transferase activity relationship: positively_regulates GO:0016740 ! transferase activity [Term] id: GO:0051348 name: negative regulation of transferase activity namespace: biological_process def: "Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor." [GOC:ai] comment: This term is useful for grouping, but is too general for manual annotation. Please use a child term instead. subset: gocheck_do_not_annotate subset: gocheck_do_not_manually_annotate synonym: "down regulation of transferase activity" EXACT [] synonym: "down-regulation of transferase activity" EXACT [] synonym: "downregulation of transferase activity" EXACT [] synonym: "inhibition of transferase activity" NARROW [] synonym: "transferase inhibitor" EXACT [] is_a: GO:0043086 ! negative regulation of catalytic activity is_a: GO:0051338 ! regulation of transferase activity intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0016740 ! transferase activity relationship: negatively_regulates GO:0016740 ! transferase activity [Term] id: GO:0051402 name: neuron apoptotic process namespace: biological_process def: "Any apoptotic process in a neuron, the basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system." [CL:0000540, GOC:mtg_apoptosis] synonym: "apoptosis of neuronal cells" EXACT [] synonym: "apoptosis of neurons" EXACT [] synonym: "neuron apoptosis" NARROW [] synonym: "neuron programmed cell death by apoptosis" EXACT [] synonym: "neuronal cell apoptosis" EXACT [] synonym: "neuronal cell programmed cell death by apoptosis" EXACT [] synonym: "programmed cell death of neuronal cells by apoptosis" EXACT [] synonym: "programmed cell death of neurons by apoptosis" EXACT [] synonym: "programmed cell death, neuronal cells" EXACT [] synonym: "programmed cell death, neurons" EXACT [] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000540 ! neuron relationship: occurs_in CL:0000540 ! neuron [Term] id: GO:0051410 name: detoxification of nitrogen compound namespace: biological_process def: "Any process that reduces or removes the toxicity of nitrogenous compounds which are dangerous or toxic. This includes the aerobic conversion of toxic compounds to harmless substances." [GOC:ai] synonym: "detoxification of nitrogenous compound" EXACT [] synonym: "nitric oxide (NO) detoxification" NARROW [] is_a: GO:0098754 ! detoxification intersection_of: GO:0098754 ! detoxification intersection_of: has_primary_input CHEBI:51143 ! nitrogen molecular entity relationship: has_primary_input CHEBI:51143 ! nitrogen molecular entity relationship: part_of GO:1901698 ! response to nitrogen compound [Term] id: GO:0051445 name: regulation of meiotic cell cycle namespace: biological_process def: "Any process that modulates the rate or extent of progression through the meiotic cell cycle." [GOC:ai, GOC:dph, GOC:tb] synonym: "meiotic cell cycle modulation" EXACT [] synonym: "meiotic cell cycle regulation" EXACT [] synonym: "meiotic cell cycle regulator" RELATED [] synonym: "modulation of meiotic cell cycle progression" EXACT [] synonym: "regulation of meiotic cell cycle progression" EXACT [] synonym: "regulation of progression through meiotic cell cycle" EXACT [GOC:dph, GOC:tb] is_a: GO:0051726 ! regulation of cell cycle is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0051321 ! meiotic cell cycle relationship: regulates GO:0051321 ! meiotic cell cycle [Term] id: GO:0051446 name: positive regulation of meiotic cell cycle namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle." [GOC:ai, GOC:dph, GOC:tb] synonym: "activation of progression through meiotic cell cycle" NARROW [] synonym: "positive regulation of meiotic cell cycle progression" EXACT [] synonym: "positive regulation of progression through meiotic cell cycle" EXACT [GOC:dph, GOC:tb] synonym: "stimulation of progression through meiotic cell cycle" NARROW [] synonym: "up regulation of progression through meiotic cell cycle" EXACT [] synonym: "up-regulation of progression through meiotic cell cycle" EXACT [] synonym: "upregulation of progression through meiotic cell cycle" EXACT [] is_a: GO:0045787 ! positive regulation of cell cycle is_a: GO:0051445 ! regulation of meiotic cell cycle is_a: GO:2000243 ! positive regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0051321 ! meiotic cell cycle relationship: positively_regulates GO:0051321 ! meiotic cell cycle [Term] id: GO:0051447 name: negative regulation of meiotic cell cycle namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of progression through the meiotic cell cycle." [GOC:ai, GOC:dph, GOC:tb] synonym: "down regulation of progression through meiotic cell cycle" EXACT [] synonym: "down-regulation of progression through meiotic cell cycle" EXACT [] synonym: "downregulation of progression through meiotic cell cycle" EXACT [] synonym: "inhibition of progression through meiotic cell cycle" NARROW [] synonym: "negative regulation of meiotic cell cycle progression" EXACT [] synonym: "negative regulation of progression through meiotic cell cycle" EXACT [GOC:dph, GOC:tb] is_a: GO:0045786 ! negative regulation of cell cycle is_a: GO:0051445 ! regulation of meiotic cell cycle is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0051321 ! meiotic cell cycle relationship: negatively_regulates GO:0051321 ! meiotic cell cycle [Term] id: GO:0051450 name: myoblast proliferation namespace: biological_process def: "The multiplication or reproduction of myoblasts, resulting in the expansion of a myoblast cell population. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:ai, GOC:mtg_muscle] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000056 ! myoblast relationship: acts_on_population_of CL:0000056 ! myoblast [Term] id: GO:0051451 name: myoblast migration namespace: biological_process def: "The orderly movement of a myoblast from one site to another, often during the development of a multicellular organism. A myoblast is a cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:ai, GOC:mtg_muscle] is_a: GO:0014812 ! muscle cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000056 ! myoblast relationship: results_in_movement_of CL:0000056 ! myoblast [Term] id: GO:0051469 name: vesicle fusion with vacuole namespace: biological_process alt_id: GO:0042146 def: "The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the vacuole." [GOC:ai] synonym: "heterotypic vacuole fusion (non-autophagic)" RELATED [] synonym: "heterotypic vacuole fusion, non-autophagic" RELATED [] is_a: GO:0006906 ! vesicle fusion is_a: GO:0097576 ! vacuole fusion intersection_of: GO:0009987 ! cellular process intersection_of: results_in_fusion_of GO:0005773 ! vacuole intersection_of: results_in_fusion_of GO:0031982 ! vesicle relationship: results_in_fusion_of GO:0031982 ! vesicle [Term] id: GO:0051493 name: regulation of cytoskeleton organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures." [GOC:ai] synonym: "regulation of cytoskeleton organisation" EXACT [GOC:mah] synonym: "regulation of cytoskeleton organization and biogenesis" RELATED [GOC:mah] is_a: GO:0033043 ! regulation of organelle organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007010 ! cytoskeleton organization relationship: regulates GO:0007010 ! cytoskeleton organization [Term] id: GO:0051494 name: negative regulation of cytoskeleton organization namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures." [GOC:ai] synonym: "down regulation of cytoskeleton organization" EXACT [] synonym: "down-regulation of cytoskeleton organization" EXACT [] synonym: "downregulation of cytoskeleton organization" EXACT [] synonym: "inhibition of cytoskeleton organization" NARROW [] synonym: "negative regulation of cytoskeleton organisation" EXACT [GOC:mah] synonym: "negative regulation of cytoskeleton organization and biogenesis" RELATED [GOC:mah] is_a: GO:0010639 ! negative regulation of organelle organization is_a: GO:0051493 ! regulation of cytoskeleton organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007010 ! cytoskeleton organization relationship: negatively_regulates GO:0007010 ! cytoskeleton organization [Term] id: GO:0051495 name: positive regulation of cytoskeleton organization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures." [GOC:ai] synonym: "activation of cytoskeleton organization" NARROW [] synonym: "positive regulation of cytoskeleton organisation" EXACT [GOC:mah] synonym: "positive regulation of cytoskeleton organization and biogenesis" RELATED [GOC:mah] synonym: "stimulation of cytoskeleton organization" NARROW [] synonym: "up regulation of cytoskeleton organization" EXACT [] synonym: "up-regulation of cytoskeleton organization" EXACT [] synonym: "upregulation of cytoskeleton organization" EXACT [] is_a: GO:0010638 ! positive regulation of organelle organization is_a: GO:0051493 ! regulation of cytoskeleton organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007010 ! cytoskeleton organization relationship: positively_regulates GO:0007010 ! cytoskeleton organization [Term] id: GO:0051588 name: regulation of neurotransmitter transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006836 ! neurotransmitter transport relationship: regulates GO:0006836 ! neurotransmitter transport [Term] id: GO:0051589 name: negative regulation of neurotransmitter transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "down regulation of neurotransmitter transport" EXACT [] synonym: "down-regulation of neurotransmitter transport" EXACT [] synonym: "downregulation of neurotransmitter transport" EXACT [] synonym: "inhibition of neurotransmitter transport" NARROW [] is_a: GO:0051051 ! negative regulation of transport is_a: GO:0051588 ! regulation of neurotransmitter transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006836 ! neurotransmitter transport relationship: negatively_regulates GO:0006836 ! neurotransmitter transport [Term] id: GO:0051590 name: positive regulation of neurotransmitter transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "activation of neurotransmitter transport" NARROW [] synonym: "stimulation of neurotransmitter transport" NARROW [] synonym: "up regulation of neurotransmitter transport" EXACT [] synonym: "up-regulation of neurotransmitter transport" EXACT [] synonym: "upregulation of neurotransmitter transport" EXACT [] is_a: GO:0051050 ! positive regulation of transport is_a: GO:0051588 ! regulation of neurotransmitter transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006836 ! neurotransmitter transport relationship: positively_regulates GO:0006836 ! neurotransmitter transport [Term] id: GO:0051602 name: response to electrical stimulus namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus." [GOC:ai] synonym: "response to electricity" RELATED [] is_a: GO:0009628 ! response to abiotic stimulus [Term] id: GO:0051606 name: detection of stimulus namespace: biological_process def: "The series of events in which a stimulus is received by a cell or organism and converted into a molecular signal." [GOC:add, GOC:ai, GOC:dph, GOC:mah] subset: goslim_pir synonym: "perception of stimulus" RELATED [] synonym: "stimulus detection" EXACT [] synonym: "stimulus sensing" RELATED [] is_a: GO:0050896 ! response to stimulus [Term] id: GO:0051620 name: norepinephrine uptake namespace: biological_process def: "The directed movement of norepinephrine into a cell, typically presynaptic neurons or glial cells. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine." [GOC:ai] synonym: "levarterenol reuptake" EXACT [] synonym: "levarterenol uptake" EXACT [] synonym: "noradrenaline reuptake" EXACT [] synonym: "noradrenaline uptake" EXACT [] synonym: "norepinephrine import" EXACT [GOC:dph, GOC:tb] synonym: "norepinephrine reuptake" EXACT [] is_a: GO:0015874 ! norepinephrine transport is_a: GO:0090493 ! catecholamine uptake intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:72587 ! (R)-noradrenaline(1+) intersection_of: has_target_end_location GO:0005622 ! intracellular anatomical structure intersection_of: has_target_start_location GO:0005576 ! extracellular region [Term] id: GO:0051621 name: regulation of norepinephrine uptake namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter norepinephrine into a cell." [GOC:ai] synonym: "regulation of levarterenol uptake" EXACT [] synonym: "regulation of noradrenaline uptake" EXACT [] synonym: "regulation of norepinephrine import" EXACT [GOC:dph, GOC:tb] is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0051620 ! norepinephrine uptake relationship: regulates GO:0051620 ! norepinephrine uptake [Term] id: GO:0051622 name: negative regulation of norepinephrine uptake namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of norepinephrine into a cell." [GOC:ai] synonym: "down regulation of norepinephrine uptake" EXACT [] synonym: "down-regulation of norepinephrine uptake" EXACT [] synonym: "downregulation of norepinephrine uptake" EXACT [] synonym: "negative regulation of levarterenol uptake" EXACT [] synonym: "negative regulation of noradrenaline uptake" EXACT [] synonym: "negative regulation of norepinephrine import" EXACT [GOC:dph, GOC:tb] is_a: GO:0051051 ! negative regulation of transport is_a: GO:0051621 ! regulation of norepinephrine uptake intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0051620 ! norepinephrine uptake relationship: negatively_regulates GO:0051620 ! norepinephrine uptake [Term] id: GO:0051623 name: positive regulation of norepinephrine uptake namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the directed movement of norepinephrine into a cell." [GOC:ai] synonym: "activation of norepinephrine uptake" NARROW [] synonym: "positive regulation of levarterenol uptake" EXACT [] synonym: "positive regulation of noradrenaline uptake" EXACT [] synonym: "positive regulation of norepinephrine import" EXACT [GOC:dph, GOC:tb] synonym: "stimulation of norepinephrine uptake" NARROW [] synonym: "up regulation of norepinephrine uptake" EXACT [] synonym: "up-regulation of norepinephrine uptake" EXACT [] synonym: "upregulation of norepinephrine uptake" EXACT [] is_a: GO:0051050 ! positive regulation of transport is_a: GO:0051621 ! regulation of norepinephrine uptake intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0051620 ! norepinephrine uptake relationship: positively_regulates GO:0051620 ! norepinephrine uptake [Term] id: GO:0051630 name: acetylcholine uptake namespace: biological_process def: "The directed movement of acetylcholine into a cell, typically presynaptic neurons or glial cells. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." [GOC:ai] synonym: "acetylcholine import" EXACT [GOC:dph, GOC:tb] is_a: GO:0015870 ! acetylcholine transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:15355 ! acetylcholine intersection_of: has_target_end_location GO:0005622 ! intracellular anatomical structure intersection_of: has_target_start_location GO:0005576 ! extracellular region relationship: has_target_end_location GO:0005622 ! intracellular anatomical structure relationship: has_target_start_location GO:0005576 ! extracellular region [Term] id: GO:0051631 name: regulation of acetylcholine uptake namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter acetylcholine into a cell." [GOC:ai] synonym: "regulation of acetylcholine import" EXACT [GOC:dph, GOC:tb] is_a: GO:0051952 ! regulation of amine transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0051630 ! acetylcholine uptake relationship: regulates GO:0051630 ! acetylcholine uptake [Term] id: GO:0051632 name: negative regulation of acetylcholine uptake namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of acetylcholine into a cell." [GOC:ai] synonym: "down regulation of acetylcholine uptake" EXACT [] synonym: "down-regulation of acetylcholine uptake" EXACT [] synonym: "downregulation of acetylcholine uptake" EXACT [] synonym: "negative regulation of acetylcholine import" EXACT [GOC:dph, GOC:tb] is_a: GO:0051631 ! regulation of acetylcholine uptake is_a: GO:0051953 ! negative regulation of amine transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0051630 ! acetylcholine uptake relationship: negatively_regulates GO:0051630 ! acetylcholine uptake [Term] id: GO:0051633 name: positive regulation of acetylcholine uptake namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the directed movement of acetylcholine into a cell." [GOC:ai] synonym: "activation of acetylcholine uptake" NARROW [] synonym: "positive regulation of acetylcholine import" EXACT [GOC:dph, GOC:tb] synonym: "stimulation of acetylcholine uptake" NARROW [] synonym: "up regulation of acetylcholine uptake" EXACT [] synonym: "up-regulation of acetylcholine uptake" EXACT [] synonym: "upregulation of acetylcholine uptake" EXACT [] is_a: GO:0051631 ! regulation of acetylcholine uptake is_a: GO:0051954 ! positive regulation of amine transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0051630 ! acetylcholine uptake relationship: positively_regulates GO:0051630 ! acetylcholine uptake [Term] id: GO:0051640 name: organelle localization namespace: biological_process def: "Any process in which an organelle is transported to, and/or maintained in, a specific location." [GOC:ai] subset: goslim_pir synonym: "establishment and maintenance of organelle localization" EXACT [] synonym: "organelle localisation" EXACT [GOC:mah] is_a: GO:0051179 ! localization intersection_of: GO:0051179 ! localization intersection_of: has_primary_input GO:0043226 ! organelle relationship: has_primary_input GO:0043226 ! organelle relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19809" xsd:anyURI [Term] id: GO:0051641 name: cellular localization namespace: biological_process alt_id: GO:1902580 def: "A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane." [GOC:tb, GOC:vw] subset: goslim_pir synonym: "cellular localisation" EXACT [GOC:mah] synonym: "establishment and maintenance of cellular localization" EXACT [] synonym: "establishment and maintenance of localization in cell or cell membrane" EXACT [] synonym: "intracellular localization" NARROW [] synonym: "localization within cell" NARROW [] synonym: "single organism cellular localization" EXACT [GOC:TermGenie] synonym: "single-organism cellular localization" RELATED [] is_a: GO:0009987 ! cellular process is_a: GO:0051179 ! localization created_by: jl creation_date: 2013-12-18T14:04:32Z [Term] id: GO:0051645 name: Golgi localization namespace: biological_process def: "Any process in which the Golgi is transported to, and/or maintained in, a specific location within the cell." [GOC:ai] synonym: "establishment and maintenance of Golgi localization" EXACT [] synonym: "Golgi apparatus localization" EXACT [] synonym: "Golgi body localization" EXACT [] synonym: "Golgi localisation" EXACT [GOC:mah] is_a: GO:0051640 ! organelle localization intersection_of: GO:0051179 ! localization intersection_of: has_primary_input GO:0005794 ! Golgi apparatus relationship: has_primary_input GO:0005794 ! Golgi apparatus [Term] id: GO:0051647 name: nucleus localization namespace: biological_process def: "Any process in which the nucleus is transported to, and/or maintained in, a specific location within the cell." [GOC:ai] synonym: "cell nucleus localization" EXACT [] synonym: "establishment and maintenance of nucleus localization" EXACT [] synonym: "localization of nucleus" EXACT [] synonym: "nucleus localisation" EXACT [GOC:mah] is_a: GO:0051640 ! organelle localization intersection_of: GO:0051179 ! localization intersection_of: has_primary_input GO:0005634 ! nucleus relationship: has_primary_input GO:0005634 ! nucleus [Term] id: GO:0051648 name: vesicle localization namespace: biological_process def: "Any process in which a vesicle or vesicles are transported to, and/or maintained in, a specific location." [GOC:ai] synonym: "cytoplasmic vesicle localization" EXACT [] synonym: "establishment and maintenance of vesicle localization" EXACT [] synonym: "vesicle localisation" EXACT [GOC:mah] is_a: GO:0051640 ! organelle localization intersection_of: GO:0051179 ! localization intersection_of: has_primary_input GO:0031982 ! vesicle relationship: has_primary_input GO:0031982 ! vesicle [Term] id: GO:0051649 name: establishment of localization in cell namespace: biological_process def: "Any process, occuring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation." [GOC:ai, GOC:dos, GOC:dph, GOC:tb] synonym: "establishment of cellular localization" RELATED [GOC:dph, GOC:tb] synonym: "establishment of intracellular localization" NARROW [] synonym: "establishment of localisation in cell" EXACT [GOC:mah] synonym: "establishment of localization within cell" NARROW [] synonym: "positioning within cell" NARROW [] is_a: GO:0051234 ! establishment of localization intersection_of: GO:0051234 ! establishment of localization intersection_of: occurs_in CL:0000000 ! cell relationship: in_taxon NCBITaxon:131567 {all_only="true"} ! cellular organisms relationship: occurs_in CL:0000000 ! cell relationship: only_in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0051641 ! cellular localization [Term] id: GO:0051650 name: establishment of vesicle localization namespace: biological_process def: "The directed movement of a vesicle to a specific location." [GOC:ai] synonym: "establishment of vesicle localisation" EXACT [GOC:mah] is_a: GO:0051648 ! vesicle localization is_a: GO:0051649 ! establishment of localization in cell is_a: GO:0051656 ! establishment of organelle localization intersection_of: GO:0051234 ! establishment of localization intersection_of: has_primary_input GO:0031982 ! vesicle [Term] id: GO:0051656 name: establishment of organelle localization namespace: biological_process def: "The directed movement of an organelle to a specific location." [GOC:ai] synonym: "establishment of organelle localisation" EXACT [GOC:mah] is_a: GO:0051234 ! establishment of localization is_a: GO:0051640 ! organelle localization intersection_of: GO:0051234 ! establishment of localization intersection_of: has_primary_input GO:0043226 ! organelle [Term] id: GO:0051668 name: localization within membrane namespace: biological_process def: "Any process in which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a membrane." [GOC:ai] synonym: "establishment and maintenance of localization in membrane" EXACT [] synonym: "establishment and maintenance of position in membrane" EXACT [] synonym: "localisation within membrane" EXACT [GOC:mah] synonym: "localization to membrane" EXACT [] synonym: "positioning within membrane" NARROW [] is_a: GO:0051641 ! cellular localization intersection_of: GO:0051179 ! localization intersection_of: has_target_end_location GO:0016020 ! membrane relationship: has_target_end_location GO:0016020 ! membrane [Term] id: GO:0051674 name: localization of cell namespace: biological_process def: "Any process in which a cell is transported to, and/or maintained in, a specific location." [GOC:ai] synonym: "cell localization" EXACT [] synonym: "establishment and maintenance of cell localization" EXACT [] synonym: "establishment and maintenance of localization of cell" EXACT [] synonym: "localisation of cell" EXACT [GOC:mah] is_a: GO:0009987 ! cellular process is_a: GO:0051179 ! localization intersection_of: GO:0051179 ! localization intersection_of: has_primary_input CL:0000000 ! cell relationship: has_primary_input CL:0000000 ! cell [Term] id: GO:0051683 name: establishment of Golgi localization namespace: biological_process def: "The directed movement of the Golgi to a specific location." [GOC:ai] synonym: "establishment of Golgi apparatus localization" EXACT [] synonym: "establishment of Golgi body localization" EXACT [] synonym: "establishment of Golgi localisation" EXACT [GOC:mah] is_a: GO:0051645 ! Golgi localization is_a: GO:0051649 ! establishment of localization in cell is_a: GO:0051656 ! establishment of organelle localization intersection_of: GO:0051234 ! establishment of localization intersection_of: has_primary_input GO:0005794 ! Golgi apparatus [Term] id: GO:0051707 name: response to other organism namespace: biological_process alt_id: GO:0009613 alt_id: GO:0042828 def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism." [GOC:ai] is_a: GO:0043207 ! response to external biotic stimulus is_a: GO:0044419 ! biological process involved in interspecies interaction between organisms intersection_of: GO:0050896 ! response to stimulus intersection_of: has_primary_input NCBITaxon_Union:0000030 relationship: has_primary_input NCBITaxon_Union:0000030 [Term] id: GO:0051716 name: cellular response to stimulus namespace: biological_process def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell." [GOC:bf, GOC:jl] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_manually_annotate is_a: GO:0009987 ! cellular process is_a: GO:0050896 ! response to stimulus [Term] id: GO:0051726 name: regulation of cell cycle namespace: biological_process alt_id: GO:0000074 alt_id: GO:0007050 alt_id: GO:0071156 alt_id: GO:0071157 alt_id: GO:0071158 alt_id: GO:0071850 def: "Any process that modulates the rate or extent of progression through the cell cycle." [GOC:ai, GOC:dph, GOC:tb] subset: goslim_yeast synonym: "arrest of mitotic cell cycle progression" NARROW [GOC:mah] synonym: "cell cycle arrest" NARROW [] synonym: "cell cycle modulation" EXACT [] synonym: "cell cycle regulation" EXACT [] synonym: "cell cycle regulator" RELATED [] synonym: "control of cell cycle progression" EXACT [] synonym: "mitotic cell cycle arrest" NARROW [] synonym: "modulation of cell cycle progression" EXACT [] synonym: "negative regulation of cell cycle arrest" NARROW [] synonym: "positive regulation of cell cycle arrest" NARROW [] synonym: "regulation of cell cycle arrest" NARROW [] synonym: "regulation of cell cycle progression" EXACT [] synonym: "regulation of progression through cell cycle" EXACT [] synonym: "tumor suppressor" RELATED [] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007049 ! cell cycle relationship: regulates GO:0007049 ! cell cycle [Term] id: GO:0051781 name: positive regulation of cell division namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell division." [GOC:ai] synonym: "activation of cell division" NARROW [] synonym: "stimulation of cell division" NARROW [] synonym: "up regulation of cell division" EXACT [] synonym: "up-regulation of cell division" EXACT [] synonym: "upregulation of cell division" EXACT [] is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:0051302 ! regulation of cell division intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0051301 ! cell division relationship: positively_regulates GO:0051301 ! cell division [Term] id: GO:0051782 name: negative regulation of cell division namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell division." [GOC:ai] synonym: "down regulation of cell division" EXACT [] synonym: "down-regulation of cell division" EXACT [] synonym: "downregulation of cell division" EXACT [] synonym: "inhibition of cell division" NARROW [] is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:0051302 ! regulation of cell division intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0051301 ! cell division relationship: negatively_regulates GO:0051301 ! cell division [Term] id: GO:0051783 name: regulation of nuclear division namespace: biological_process def: "Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information." [GOC:ai] is_a: GO:0033043 ! regulation of organelle organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0000280 ! nuclear division relationship: regulates GO:0000280 ! nuclear division [Term] id: GO:0051784 name: negative regulation of nuclear division namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information." [GOC:ai] synonym: "down regulation of nuclear division" EXACT [] synonym: "down-regulation of nuclear division" EXACT [] synonym: "downregulation of nuclear division" EXACT [] synonym: "inhibition of nuclear division" NARROW [] is_a: GO:0010639 ! negative regulation of organelle organization is_a: GO:0051783 ! regulation of nuclear division intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0000280 ! nuclear division relationship: negatively_regulates GO:0000280 ! nuclear division [Term] id: GO:0051785 name: positive regulation of nuclear division namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information." [GOC:ai] synonym: "activation of nuclear division" NARROW [] synonym: "stimulation of nuclear division" NARROW [] synonym: "up regulation of nuclear division" EXACT [] synonym: "up-regulation of nuclear division" EXACT [] synonym: "upregulation of nuclear division" EXACT [] is_a: GO:0010638 ! positive regulation of organelle organization is_a: GO:0051783 ! regulation of nuclear division intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0000280 ! nuclear division relationship: positively_regulates GO:0000280 ! nuclear division [Term] id: GO:0051875 name: pigment granule localization namespace: biological_process def: "Any process in which a pigment granule is transported to, and/or maintained in, a specific location within the cell." [GOC:ai] synonym: "pigment granule localisation" EXACT [GOC:mah] is_a: GO:0051648 ! vesicle localization intersection_of: GO:0051179 ! localization intersection_of: has_primary_input GO:0048770 ! pigment granule relationship: has_primary_input GO:0048770 ! pigment granule relationship: part_of GO:0033059 ! cellular pigmentation [Term] id: GO:0051890 name: regulation of cardioblast differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:ai] is_a: GO:1905207 ! regulation of cardiocyte differentiation is_a: GO:2000736 ! regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0010002 ! cardioblast differentiation relationship: regulates GO:0010002 ! cardioblast differentiation [Term] id: GO:0051891 name: positive regulation of cardioblast differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:ai] synonym: "activation of cardioblast differentiation" NARROW [] synonym: "stimulation of cardioblast differentiation" NARROW [] synonym: "up regulation of cardioblast differentiation" EXACT [] synonym: "up-regulation of cardioblast differentiation" EXACT [] synonym: "upregulation of cardioblast differentiation" EXACT [] is_a: GO:0051890 ! regulation of cardioblast differentiation is_a: GO:1905209 ! positive regulation of cardiocyte differentiation is_a: GO:2000738 ! positive regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0010002 ! cardioblast differentiation relationship: positively_regulates GO:0010002 ! cardioblast differentiation [Term] id: GO:0051892 name: negative regulation of cardioblast differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:ai] synonym: "down regulation of cardioblast differentiation" EXACT [] synonym: "down-regulation of cardioblast differentiation" EXACT [] synonym: "downregulation of cardioblast differentiation" EXACT [] synonym: "inhibition of cardioblast differentiation" NARROW [] is_a: GO:0051890 ! regulation of cardioblast differentiation is_a: GO:1905208 ! negative regulation of cardiocyte differentiation is_a: GO:2000737 ! negative regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0010002 ! cardioblast differentiation relationship: negatively_regulates GO:0010002 ! cardioblast differentiation [Term] id: GO:0051904 name: pigment granule transport namespace: biological_process def: "The directed movement of pigment granules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "pigment granule translocation" EXACT [] is_a: GO:0006810 ! transport is_a: GO:0051875 ! pigment granule localization is_a: GO:0051905 ! establishment of pigment granule localization intersection_of: GO:0006810 ! transport intersection_of: has_primary_input GO:0048770 ! pigment granule [Term] id: GO:0051905 name: establishment of pigment granule localization namespace: biological_process def: "The directed movement of a pigment granule to a specific location." [GOC:ai] synonym: "establishment of pigment granule localisation" EXACT [GOC:mah] is_a: GO:0051650 ! establishment of vesicle localization relationship: part_of GO:0051875 ! pigment granule localization [Term] id: GO:0051930 name: regulation of sensory perception of pain namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal." [GOC:ai] is_a: GO:0051931 ! regulation of sensory perception intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0019233 ! sensory perception of pain relationship: regulates GO:0019233 ! sensory perception of pain [Term] id: GO:0051931 name: regulation of sensory perception namespace: biological_process def: "Any process that modulates the frequency, rate or extent of sensory perception, the series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal." [GOC:ai] is_a: GO:0031644 ! regulation of nervous system process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007600 ! sensory perception relationship: regulates GO:0007600 ! sensory perception [Term] id: GO:0051937 name: catecholamine transport namespace: biological_process def: "The directed movement of catecholamines, a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." [GOC:ai, ISBN:0198506732] is_a: GO:0015844 ! monoamine transport is_a: GO:0015850 ! organic hydroxy compound transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:33567 ! catecholamine relationship: has_primary_input CHEBI:33567 ! catecholamine [Term] id: GO:0051952 name: regulation of amine transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0015837 ! amine transport relationship: regulates GO:0015837 ! amine transport [Term] id: GO:0051953 name: negative regulation of amine transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "down regulation of amine transport" EXACT [] synonym: "down-regulation of amine transport" EXACT [] synonym: "downregulation of amine transport" EXACT [] synonym: "inhibition of amine transport" NARROW [] is_a: GO:0051051 ! negative regulation of transport is_a: GO:0051952 ! regulation of amine transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0015837 ! amine transport relationship: negatively_regulates GO:0015837 ! amine transport [Term] id: GO:0051954 name: positive regulation of amine transport namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "activation of amine transport" NARROW [] synonym: "stimulation of amine transport" NARROW [] synonym: "up regulation of amine transport" EXACT [] synonym: "up-regulation of amine transport" EXACT [] synonym: "upregulation of amine transport" EXACT [] is_a: GO:0051050 ! positive regulation of transport is_a: GO:0051952 ! regulation of amine transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0015837 ! amine transport relationship: positively_regulates GO:0015837 ! amine transport [Term] id: GO:0051955 name: regulation of amino acid transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] is_a: GO:0032890 ! regulation of organic acid transport is_a: GO:0051952 ! regulation of amine transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006865 ! amino acid transport relationship: regulates GO:0006865 ! amino acid transport [Term] id: GO:0051956 name: negative regulation of amino acid transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "down regulation of amino acid transport" EXACT [] synonym: "down-regulation of amino acid transport" EXACT [] synonym: "downregulation of amino acid transport" EXACT [] synonym: "inhibition of amino acid transport" NARROW [] synonym: "negative regulation of amino acid transmembrane transport" EXACT [GOC:mah] is_a: GO:0032891 ! negative regulation of organic acid transport is_a: GO:0051953 ! negative regulation of amine transport is_a: GO:0051955 ! regulation of amino acid transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006865 ! amino acid transport relationship: negatively_regulates GO:0006865 ! amino acid transport [Term] id: GO:0051957 name: positive regulation of amino acid transport namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "activation of amino acid transport" NARROW [] synonym: "positive regulation of amino acid transmembrane transport" EXACT [GOC:mah] synonym: "stimulation of amino acid transport" NARROW [] synonym: "up regulation of amino acid transport" EXACT [] synonym: "up-regulation of amino acid transport" EXACT [] synonym: "upregulation of amino acid transport" EXACT [] is_a: GO:0032892 ! positive regulation of organic acid transport is_a: GO:0051954 ! positive regulation of amine transport is_a: GO:0051955 ! regulation of amino acid transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006865 ! amino acid transport relationship: positively_regulates GO:0006865 ! amino acid transport [Term] id: GO:0051960 name: regulation of nervous system development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue." [GOC:ai] is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007399 ! nervous system development relationship: regulates GO:0007399 ! nervous system development [Term] id: GO:0051961 name: negative regulation of nervous system development namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue." [GOC:ai] synonym: "down regulation of nervous system development" EXACT [] synonym: "down-regulation of nervous system development" EXACT [] synonym: "downregulation of nervous system development" EXACT [] synonym: "inhibition of nervous system development" NARROW [] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:0051960 ! regulation of nervous system development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007399 ! nervous system development relationship: negatively_regulates GO:0007399 ! nervous system development [Term] id: GO:0051962 name: positive regulation of nervous system development namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue." [GOC:ai] synonym: "activation of nervous system development" NARROW [] synonym: "stimulation of nervous system development" NARROW [] synonym: "up regulation of nervous system development" EXACT [] synonym: "up-regulation of nervous system development" EXACT [] synonym: "upregulation of nervous system development" EXACT [] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:0051960 ! regulation of nervous system development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007399 ! nervous system development relationship: positively_regulates GO:0007399 ! nervous system development [Term] id: GO:0051963 name: regulation of synapse assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse." [GOC:ai, GOC:pr] subset: goslim_synapse synonym: "regulation of synapse biogenesis" EXACT [] synonym: "regulation of synaptogenesis" EXACT [] is_a: GO:0050807 ! regulation of synapse organization is_a: GO:1901888 ! regulation of cell junction assembly intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007416 ! synapse assembly relationship: regulates GO:0007416 ! synapse assembly [Term] id: GO:0051964 name: negative regulation of synapse assembly namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse." [GOC:ai, GOC:pr] synonym: "down regulation of synapse assembly" EXACT [] synonym: "down-regulation of synapse assembly" EXACT [] synonym: "downregulation of synapse assembly" EXACT [] synonym: "inhibition of synapse assembly" NARROW [] synonym: "negative regulation of synapse biogenesis" EXACT [] synonym: "negative regulation of synaptogenesis" EXACT [] is_a: GO:0051961 ! negative regulation of nervous system development is_a: GO:0051963 ! regulation of synapse assembly is_a: GO:1901889 ! negative regulation of cell junction assembly is_a: GO:1905809 ! negative regulation of synapse organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007416 ! synapse assembly relationship: negatively_regulates GO:0007416 ! synapse assembly [Term] id: GO:0051965 name: positive regulation of synapse assembly namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse." [GOC:ai, GOC:pr] synonym: "activation of synapse assembly" NARROW [] synonym: "positive regulation of synapse biogenesis" EXACT [] synonym: "positive regulation of synaptogenesis" EXACT [] synonym: "stimulation of synapse assembly" NARROW [] synonym: "up regulation of synapse assembly" EXACT [] synonym: "up-regulation of synapse assembly" EXACT [] synonym: "upregulation of synapse assembly" EXACT [] is_a: GO:0051962 ! positive regulation of nervous system development is_a: GO:0051963 ! regulation of synapse assembly is_a: GO:1901890 ! positive regulation of cell junction assembly intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007416 ! synapse assembly relationship: positively_regulates GO:0007416 ! synapse assembly [Term] id: GO:0051969 name: regulation of transmission of nerve impulse namespace: biological_process def: "Any process that modulates the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation." [GOC:ai] synonym: "regulation of conduction of nerve impulse" EXACT [GOC:dph] is_a: GO:0010646 ! regulation of cell communication is_a: GO:0031644 ! regulation of nervous system process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0019226 ! transmission of nerve impulse relationship: regulates GO:0019226 ! transmission of nerve impulse [Term] id: GO:0051970 name: negative regulation of transmission of nerve impulse namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation." [GOC:ai] synonym: "down regulation of transmission of nerve impulse" EXACT [] synonym: "down-regulation of transmission of nerve impulse" EXACT [] synonym: "downregulation of transmission of nerve impulse" EXACT [] synonym: "inhibition of transmission of nerve impulse" NARROW [] synonym: "negative regulation of conduction of nerve impulse" EXACT [GOC:dph] is_a: GO:0010648 ! negative regulation of cell communication is_a: GO:0031645 ! negative regulation of nervous system process is_a: GO:0051969 ! regulation of transmission of nerve impulse intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0019226 ! transmission of nerve impulse relationship: negatively_regulates GO:0019226 ! transmission of nerve impulse [Term] id: GO:0051971 name: positive regulation of transmission of nerve impulse namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation." [GOC:ai] synonym: "activation of transmission of nerve impulse" NARROW [] synonym: "positive regulation of conduction of nerve impulse" EXACT [GOC:dph] synonym: "stimulation of transmission of nerve impulse" NARROW [] synonym: "up regulation of transmission of nerve impulse" EXACT [] synonym: "up-regulation of transmission of nerve impulse" EXACT [] synonym: "upregulation of transmission of nerve impulse" EXACT [] is_a: GO:0010647 ! positive regulation of cell communication is_a: GO:0031646 ! positive regulation of nervous system process is_a: GO:0051969 ! regulation of transmission of nerve impulse intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0019226 ! transmission of nerve impulse relationship: positively_regulates GO:0019226 ! transmission of nerve impulse [Term] id: GO:0051983 name: regulation of chromosome segregation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets." [GOC:ai] is_a: GO:0010564 ! regulation of cell cycle process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007059 ! chromosome segregation relationship: regulates GO:0007059 ! chromosome segregation [Term] id: GO:0051984 name: positive regulation of chromosome segregation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets." [GOC:ai] synonym: "activation of chromosome segregation" NARROW [] synonym: "stimulation of chromosome segregation" NARROW [] synonym: "up regulation of chromosome segregation" EXACT [] synonym: "up-regulation of chromosome segregation" EXACT [] synonym: "upregulation of chromosome segregation" EXACT [] is_a: GO:0051983 ! regulation of chromosome segregation is_a: GO:0090068 ! positive regulation of cell cycle process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007059 ! chromosome segregation relationship: positively_regulates GO:0007059 ! chromosome segregation [Term] id: GO:0051985 name: negative regulation of chromosome segregation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets." [GOC:ai] synonym: "down regulation of chromosome segregation" EXACT [] synonym: "down-regulation of chromosome segregation" EXACT [] synonym: "downregulation of chromosome segregation" EXACT [] synonym: "inhibition of chromosome segregation" NARROW [] is_a: GO:0010948 ! negative regulation of cell cycle process is_a: GO:0051983 ! regulation of chromosome segregation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007059 ! chromosome segregation relationship: negatively_regulates GO:0007059 ! chromosome segregation [Term] id: GO:0055001 name: muscle cell development namespace: biological_process alt_id: GO:0048747 def: "The process whose specific outcome is the progression of a muscle cell over time, from its formation to the mature structure. Muscle cell development does not include the steps involved in committing an unspecified cell to the muscle cell fate." [CL:0000187, GOC:devbiol] synonym: "muscle fiber development" EXACT [] synonym: "muscle fibre development" EXACT [] synonym: "myofiber development" EXACT [] synonym: "myofibre development" EXACT [] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000187 ! muscle cell relationship: part_of GO:0042692 ! muscle cell differentiation relationship: results_in_development_of CL:0000187 ! muscle cell [Term] id: GO:0055002 name: striated muscle cell development namespace: biological_process def: "The process whose specific outcome is the progression of a striated muscle cell over time, from its formation to the mature structure. Striated muscle cells contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle." [CL:0000737, GOC:devbiol] is_a: GO:0055001 ! muscle cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000737 ! striated muscle cell relationship: part_of GO:0051146 ! striated muscle cell differentiation relationship: results_in_development_of CL:0000737 ! striated muscle cell [Term] id: GO:0055003 name: cardiac myofibril assembly namespace: biological_process def: "The process whose specific outcome is the progression of the cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells." [GOC:devbiol] synonym: "cardiac myofibril development" EXACT [] synonym: "cardiac myofibril morphogenesis" EXACT [] synonym: "heart myofibril assembly" RELATED [] is_a: GO:0030239 ! myofibril assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0097512 ! cardiac myofibril relationship: part_of GO:0055013 ! cardiac muscle cell development relationship: results_in_assembly_of GO:0097512 ! cardiac myofibril [Term] id: GO:0055006 name: cardiac cell development namespace: biological_process def: "The process whose specific outcome is the progression of a cardiac cell over time, from its formation to the mature state. A cardiac cell is a cell that will form part of the cardiac organ of an individual." [GOC:devbiol] synonym: "cardiocyte development" EXACT [GOC:dph] synonym: "heart cell development" RELATED [] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0002494 ! cardiocyte relationship: part_of GO:0035051 ! cardiocyte differentiation relationship: results_in_development_of CL:0002494 ! cardiocyte [Term] id: GO:0055007 name: cardiac muscle cell differentiation namespace: biological_process def: "The process in which a cardiac muscle precursor cell acquires specialized features of a cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction." [GOC:devbiol, GOC:mtg_heart] synonym: "cardiomyocyte differentiation" EXACT [] synonym: "heart muscle cell differentiation" RELATED [] is_a: GO:0035051 ! cardiocyte differentiation is_a: GO:0051146 ! striated muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000746 ! cardiac muscle cell relationship: part_of GO:0048738 ! cardiac muscle tissue development relationship: results_in_acquisition_of_features_of CL:0000746 ! cardiac muscle cell [Term] id: GO:0055008 name: cardiac muscle tissue morphogenesis namespace: biological_process def: "The process in which the anatomical structures of cardiac muscle tissue are generated and organized." [GOC:devbiol] synonym: "heart muscle morphogenesis" EXACT [] synonym: "myocardium morphogenesis" BROAD [GOC:mtg_heart] is_a: GO:0060415 ! muscle tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001133 ! cardiac muscle tissue relationship: part_of GO:0003007 ! heart morphogenesis relationship: part_of GO:0048738 ! cardiac muscle tissue development relationship: results_in_morphogenesis_of UBERON:0001133 ! cardiac muscle tissue [Term] id: GO:0055009 name: atrial cardiac muscle tissue morphogenesis namespace: biological_process def: "The process in which the anatomical structure of cardiac atrium muscle is generated and organized." [GOC:devbiol] synonym: "atrial heart muscle morphogenesis" EXACT [] synonym: "atrial myocardium morphogenesis" EXACT [GOC:mtg_heart] synonym: "cardiac atrium muscle morphogenesis" EXACT [] is_a: GO:0055008 ! cardiac muscle tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0004490 ! cardiac muscle tissue of atrium relationship: part_of GO:0003209 ! cardiac atrium morphogenesis relationship: part_of GO:0003228 ! atrial cardiac muscle tissue development relationship: results_in_morphogenesis_of UBERON:0004490 ! cardiac muscle tissue of atrium [Term] id: GO:0055010 name: ventricular cardiac muscle tissue morphogenesis namespace: biological_process def: "The process in which the anatomical structures of cardiac ventricle muscle is generated and organized." [GOC:devbiol] synonym: "cardiac ventricle muscle morphogenesis" EXACT [] synonym: "ventricular heart muscle morphogenesis" EXACT [] is_a: GO:0055008 ! cardiac muscle tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0018649 ! cardiac muscle tissue of ventricle relationship: part_of GO:0003208 ! cardiac ventricle morphogenesis relationship: part_of GO:0003229 ! ventricular cardiac muscle tissue development relationship: results_in_morphogenesis_of UBERON:0018649 ! cardiac muscle tissue of ventricle [Term] id: GO:0055013 name: cardiac muscle cell development namespace: biological_process alt_id: GO:0048739 def: "The process whose specific outcome is the progression of a cardiac muscle cell over time, from its formation to the mature state." [GOC:devbiol, GOC:mtg_heart] synonym: "cardiac muscle fiber development" EXACT [] synonym: "cardiac muscle fibre development" EXACT [] synonym: "cardiomyocyte cell development" EXACT [GOC:mtg_muscle] synonym: "heart muscle cell development" EXACT [] synonym: "heart muscle fiber development" RELATED [] is_a: GO:0055002 ! striated muscle cell development is_a: GO:0055006 ! cardiac cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000746 ! cardiac muscle cell relationship: part_of GO:0055007 ! cardiac muscle cell differentiation relationship: results_in_development_of CL:0000746 ! cardiac muscle cell [Term] id: GO:0055017 name: cardiac muscle tissue growth namespace: biological_process def: "The increase in size or mass of a cardiac muscle, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another." [GOC:devbiol] synonym: "heart muscle growth" EXACT [] is_a: GO:0048589 ! developmental growth intersection_of: GO:0048589 ! developmental growth intersection_of: results_in_growth_of UBERON:0001133 ! cardiac muscle tissue relationship: part_of GO:0048738 ! cardiac muscle tissue development relationship: part_of GO:0060419 ! heart growth relationship: results_in_growth_of UBERON:0001133 ! cardiac muscle tissue [Term] id: GO:0055018 name: regulation of cardiac muscle fiber development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac muscle fiber development." [GOC:vk] synonym: "regulation of cardiac muscle fibre development" EXACT [] synonym: "regulation of heart muscle fiber development" EXACT [] is_a: GO:0060284 ! regulation of cell development is_a: GO:2000725 ! regulation of cardiac muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0055013 ! cardiac muscle cell development relationship: regulates GO:0055013 ! cardiac muscle cell development [Term] id: GO:0055019 name: negative regulation of cardiac muscle fiber development namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle fiber development." [GOC:vk] synonym: "down regulation of cardiac muscle fiber development" EXACT [] synonym: "down-regulation of cardiac muscle fiber development" EXACT [] synonym: "downregulation of cardiac muscle fiber development" EXACT [] synonym: "inhibition of cardiac muscle fiber development" NARROW [] synonym: "negative regulation of cardiac muscle fibre development" EXACT [] synonym: "negative regulation of heart muscle fiber development" RELATED [] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0051154 ! negative regulation of striated muscle cell differentiation is_a: GO:0055018 ! regulation of cardiac muscle fiber development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0055013 ! cardiac muscle cell development relationship: negatively_regulates GO:0055013 ! cardiac muscle cell development [Term] id: GO:0055020 name: positive regulation of cardiac muscle fiber development namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle fiber development." [GOC:vk] synonym: "activation of cardiac muscle fiber development" NARROW [] synonym: "positive regulation of cardiac muscle fibre development" EXACT [] synonym: "positive regulation of heart muscle fiber development" EXACT [] synonym: "stimulation of cardiac muscle fiber development" NARROW [] synonym: "up regulation of cardiac muscle fiber development" EXACT [] synonym: "up-regulation of cardiac muscle fiber development" EXACT [] synonym: "upregulation of cardiac muscle fiber development" EXACT [] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0055018 ! regulation of cardiac muscle fiber development is_a: GO:2000727 ! positive regulation of cardiac muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0055013 ! cardiac muscle cell development relationship: positively_regulates GO:0055013 ! cardiac muscle cell development [Term] id: GO:0055021 name: regulation of cardiac muscle tissue growth namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac muscle growth." [GOC:vk] is_a: GO:0060420 ! regulation of heart growth intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0055017 ! cardiac muscle tissue growth relationship: regulates GO:0055017 ! cardiac muscle tissue growth [Term] id: GO:0055022 name: negative regulation of cardiac muscle tissue growth namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle growth." [GOC:vk] synonym: "down regulation of cardiac muscle growth" EXACT [] synonym: "down-regulation of cardiac muscle growth" EXACT [] synonym: "downregulation of cardiac muscle growth" EXACT [] synonym: "inhibition of cardiac muscle growth" NARROW [] synonym: "negative regulation of heart muscle growth" RELATED [] is_a: GO:0055021 ! regulation of cardiac muscle tissue growth is_a: GO:0061117 ! negative regulation of heart growth intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0055017 ! cardiac muscle tissue growth relationship: negatively_regulates GO:0055017 ! cardiac muscle tissue growth [Term] id: GO:0055023 name: positive regulation of cardiac muscle tissue growth namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle growth." [GOC:vk] synonym: "activation of cardiac muscle growth" NARROW [] synonym: "positive regulation of heart muscle growth" EXACT [] synonym: "stimulation of cardiac muscle growth" NARROW [] synonym: "up regulation of cardiac muscle growth" EXACT [] synonym: "up-regulation of cardiac muscle growth" EXACT [] synonym: "upregulation of cardiac muscle growth" EXACT [] is_a: GO:0055021 ! regulation of cardiac muscle tissue growth is_a: GO:0060421 ! positive regulation of heart growth intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0055017 ! cardiac muscle tissue growth relationship: positively_regulates GO:0055017 ! cardiac muscle tissue growth [Term] id: GO:0055024 name: regulation of cardiac muscle tissue development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac muscle tissue development." [GOC:vk] synonym: "regulation of heart muscle development" EXACT [] is_a: GO:0016202 ! regulation of striated muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048738 ! cardiac muscle tissue development relationship: regulates GO:0048738 ! cardiac muscle tissue development [Term] id: GO:0055025 name: positive regulation of cardiac muscle tissue development namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle tissue development." [GOC:vk] synonym: "activation of cardiac muscle development" NARROW [] synonym: "positive regulation of heart muscle development" EXACT [] synonym: "stimulation of cardiac muscle development" NARROW [] synonym: "up regulation of cardiac muscle development" EXACT [] synonym: "up-regulation of cardiac muscle development" EXACT [] synonym: "upregulation of cardiac muscle development" EXACT [] is_a: GO:0045844 ! positive regulation of striated muscle tissue development is_a: GO:0055024 ! regulation of cardiac muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048738 ! cardiac muscle tissue development relationship: positively_regulates GO:0048738 ! cardiac muscle tissue development [Term] id: GO:0055026 name: negative regulation of cardiac muscle tissue development namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle tissue development." [GOC:vk] synonym: "down regulation of cardiac muscle development" EXACT [] synonym: "down-regulation of cardiac muscle development" EXACT [] synonym: "downregulation of cardiac muscle development" EXACT [] synonym: "inhibition of cardiac muscle development" NARROW [] synonym: "negative regulation of heart muscle development" EXACT [] is_a: GO:0045843 ! negative regulation of striated muscle tissue development is_a: GO:0055024 ! regulation of cardiac muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048738 ! cardiac muscle tissue development relationship: negatively_regulates GO:0048738 ! cardiac muscle tissue development [Term] id: GO:0055057 name: neuroblast division namespace: biological_process def: "The process resulting in the physical partitioning and separation of a neuroblast into daughter cells. A neuroblast is any cell that will divide and give rise to a neuron." [PMID:11163136, PMID:11250167] synonym: "neuroblast cell division" EXACT [] is_a: GO:0051301 ! cell division intersection_of: GO:0051301 ! cell division intersection_of: has_primary_input CL:0000031 ! neuroblast (sensu Vertebrata) relationship: has_primary_input CL:0000031 ! neuroblast (sensu Vertebrata) relationship: part_of GO:0007405 ! neuroblast proliferation [Term] id: GO:0055059 name: asymmetric neuroblast division namespace: biological_process def: "The process resulting in the physical partitioning and separation of a neuroblast into two daughter cells with different developmental potentials." [GOC:dph] is_a: GO:0008356 ! asymmetric cell division is_a: GO:0045165 ! cell fate commitment is_a: GO:0055057 ! neuroblast division intersection_of: GO:0008356 ! asymmetric cell division intersection_of: has_primary_input CL:0000031 ! neuroblast (sensu Vertebrata) [Term] id: GO:0055085 name: transmembrane transport namespace: biological_process alt_id: GO:0090662 def: "The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other." [GOC:dph, GOC:jid] comment: Transmembrane transport is the transport of a solute across a lipid bilayer. Note that transport through the nuclear pore complex is not transmembrane because the nuclear membrane is a double membrane and is not traversed. For transport through the nuclear pore, consider instead the term 'nucleocytoplasmic transport ; GO:0006913' and its children. Note also that this term is not intended for use in annotating lateral movement within membranes. subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_pombe subset: goslim_yeast synonym: "ATP hydrolysis coupled transmembrane transport" NARROW [] synonym: "membrane transport" EXACT [] is_a: GO:0006810 ! transport is_a: GO:0009987 ! cellular process intersection_of: GO:0006810 ! transport intersection_of: results_in_transport_across GO:0016020 ! membrane relationship: results_in_transport_across GO:0016020 ! membrane created_by: tb creation_date: 2015-10-21T13:22:47Z [Term] id: GO:0055086 name: nucleobase-containing small molecule metabolic process namespace: biological_process def: "The cellular chemical reactions and pathways involving a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide." [GOC:vw] subset: goslim_drosophila subset: goslim_generic subset: goslim_pombe subset: goslim_prokaryote subset: goslim_yeast synonym: "nucleobase, nucleoside and nucleotide metabolic process" RELATED [] synonym: "nucleobase, nucleoside and nucleotide metabolism" EXACT [] is_a: GO:0006139 ! nucleobase-containing compound metabolic process is_a: GO:0044281 ! small molecule metabolic process [Term] id: GO:0055107 name: Golgi to secretory granule transport namespace: biological_process def: "The directed movement of proteins from the Golgi to a secretory granule. The secretory granule is a membrane-bounded particle, usually protein, formed in the granular endoplasmic reticulum and the Golgi complex." [GOC:curators] is_a: GO:0046907 ! intracellular transport intersection_of: GO:0006810 ! transport intersection_of: has_target_end_location GO:0030141 ! secretory granule intersection_of: has_target_start_location GO:0005794 ! Golgi apparatus intersection_of: occurs_in GO:0005737 ! cytoplasm relationship: has_target_end_location GO:0030141 ! secretory granule relationship: has_target_start_location GO:0005794 ! Golgi apparatus relationship: occurs_in GO:0005737 ! cytoplasm [Term] id: GO:0055108 name: Golgi to transport vesicle transport namespace: biological_process def: "The directed movement of proteins from the Golgi to a transport vesicle. Continuously secreted proteins are sorted into transport vesicles that fuse with the plasma membrane, releasing their contents by exocytosis." [GOC:jid] is_a: GO:0046907 ! intracellular transport intersection_of: GO:0006810 ! transport intersection_of: has_target_end_location GO:0030133 ! transport vesicle intersection_of: has_target_start_location GO:0005794 ! Golgi apparatus intersection_of: occurs_in GO:0005737 ! cytoplasm relationship: has_target_end_location GO:0030133 ! transport vesicle relationship: has_target_start_location GO:0005794 ! Golgi apparatus relationship: occurs_in GO:0005737 ! cytoplasm relationship: part_of GO:0048193 ! Golgi vesicle transport [Term] id: GO:0055111 name: ingression involved in gastrulation with mouth forming second namespace: biological_process def: "The migration of individual cells into the embryo involved in deuterostomic gastrulation." [ISBN:0878932437] is_a: GO:0042074 ! cell migration involved in gastrulation intersection_of: GO:0001667 ! ameboidal-type cell migration intersection_of: part_of GO:0001702 ! gastrulation with mouth forming second relationship: part_of GO:0001702 ! gastrulation with mouth forming second [Term] id: GO:0055117 name: regulation of cardiac muscle contraction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac muscle contraction." [GOC:ecd] is_a: GO:0006942 ! regulation of striated muscle contraction is_a: GO:0008016 ! regulation of heart contraction intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060048 ! cardiac muscle contraction relationship: regulates GO:0060048 ! cardiac muscle contraction [Term] id: GO:0055118 name: negative regulation of cardiac muscle contraction namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle contraction." [GOC:ecd] is_a: GO:0045822 ! negative regulation of heart contraction is_a: GO:0045988 ! negative regulation of striated muscle contraction is_a: GO:0055117 ! regulation of cardiac muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060048 ! cardiac muscle contraction relationship: negatively_regulates GO:0060048 ! cardiac muscle contraction [Term] id: GO:0055123 name: digestive system development namespace: biological_process def: "The process whose specific outcome is the progression of the digestive system over time, from its formation to the mature structure. The digestive system is the entire structure in which digestion takes place. Digestion is all of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." [GOC:jid] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001007 ! digestive system relationship: results_in_development_of UBERON:0001007 ! digestive system [Term] id: GO:0060008 name: Sertoli cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules." [GOC:dph] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0030855 ! epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000216 ! Sertoli cell relationship: part_of GO:0008584 ! male gonad development relationship: results_in_acquisition_of_features_of CL:0000216 ! Sertoli cell [Term] id: GO:0060009 name: Sertoli cell development namespace: biological_process def: "The process whose specific outcome is the progression of a Sertoli cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a Sertoli cell fate." [GOC:dph] is_a: GO:0002064 ! epithelial cell development is_a: GO:0003006 ! developmental process involved in reproduction intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000216 ! Sertoli cell relationship: part_of GO:0060008 ! Sertoli cell differentiation relationship: results_in_development_of CL:0000216 ! Sertoli cell [Term] id: GO:0060011 name: Sertoli cell proliferation namespace: biological_process def: "The multiplication or reproduction of Sertoli cells, resulting in the expansion of the Sertoli cell population. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules." [GOC:dph] is_a: GO:0022414 ! reproductive process is_a: GO:0050673 ! epithelial cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000216 ! Sertoli cell relationship: acts_on_population_of CL:0000216 ! Sertoli cell relationship: part_of GO:0008584 ! male gonad development [Term] id: GO:0060021 name: roof of mouth development namespace: biological_process def: "The biological process whose specific outcome is the progression of the roof of the mouth from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The roof of the mouth is the partition that separates the nasal and oral cavities." [GOC:dph, ISBN:0721662544] synonym: "palatum development" EXACT [ISBN:0721662544] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0007375 ! roof of mouth relationship: results_in_development_of UBERON:0007375 ! roof of mouth [Term] id: GO:0060037 name: pharyngeal system development namespace: biological_process def: "The process whose specific outcome is the progression of the pharyngeal system over time, from its formation to the mature structure. The pharyngeal system is a transient embryonic complex that is specific to vertebrates. It comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the stucture it contributes to are forming: the thymus, thyroid, parathyroids, maxilla, mandible, aortic arch, cardiac outflow tract, external and middle ear." [GOC:dph] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0008814 ! pharyngeal arch system relationship: part_of GO:0043009 ! chordate embryonic development relationship: results_in_development_of UBERON:0008814 ! pharyngeal arch system [Term] id: GO:0060038 name: cardiac muscle cell proliferation namespace: biological_process def: "The expansion of a cardiac muscle cell population by cell division." [GOC:dph, GOC:rph, PMID:11161571] synonym: "cardiac myocyte proliferation" EXACT [] synonym: "cardiomyocyte proliferation" RELATED [GOC:dph, PMID:10074473] synonym: "heart muscle cell proliferation" EXACT [] is_a: GO:0014855 ! striated muscle cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000746 ! cardiac muscle cell relationship: acts_on_population_of CL:0000746 ! cardiac muscle cell relationship: part_of GO:0055017 ! cardiac muscle tissue growth [Term] id: GO:0060039 name: pericardium development namespace: biological_process def: "The process whose specific outcome is the progression of the pericardium over time, from its formation to the mature structure. The pericardium is a double-walled sac that contains the heart and the roots of the aorta, vena cava and the pulmonary artery." [GOC:dph, GOC:rph, PMID:15138308, PMID:16376438] is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002407 ! pericardium relationship: part_of GO:0007507 ! heart development relationship: results_in_development_of UBERON:0002407 ! pericardium [Term] id: GO:0060041 name: retina development in camera-type eye namespace: biological_process alt_id: GO:0002073 def: "The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates." [GOC:bf, GOC:dph, ISBN:0815340729] synonym: "retina development in camera-style eye" EXACT [] synonym: "retinal development" RELATED [GOC:dph, GOC:tb] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: part_of GO:0043010 ! camera-type eye development intersection_of: results_in_development_of UBERON:0000966 ! retina relationship: part_of GO:0043010 ! camera-type eye development relationship: results_in_development_of UBERON:0000966 ! retina [Term] id: GO:0060042 name: retina morphogenesis in camera-type eye namespace: biological_process def: "The process in which the anatomical structure of the retina is generated and organized." [GOC:bf, GOC:dph, GOC:mtg_sensu] synonym: "retina morphogenesis in camera-style eye" EXACT [] synonym: "retinogenesis" EXACT [] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000966 ! retina relationship: part_of GO:0048593 ! camera-type eye morphogenesis relationship: part_of GO:0060041 ! retina development in camera-type eye relationship: results_in_morphogenesis_of UBERON:0000966 ! retina [Term] id: GO:0060043 name: regulation of cardiac muscle cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac muscle cell proliferation." [GOC:dph, GOC:rph] synonym: "regulation of cardiomyocyte proliferation" RELATED [GOC:dph] synonym: "regulation of heart muscle cell proliferation" EXACT [] is_a: GO:0042127 ! regulation of cell population proliferation is_a: GO:0055021 ! regulation of cardiac muscle tissue growth intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060038 ! cardiac muscle cell proliferation relationship: regulates GO:0060038 ! cardiac muscle cell proliferation [Term] id: GO:0060044 name: negative regulation of cardiac muscle cell proliferation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell proliferation." [GOC:dph, GOC:rph] synonym: "negative regulation of heart muscle cell proliferation" EXACT [] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0055022 ! negative regulation of cardiac muscle tissue growth is_a: GO:0060043 ! regulation of cardiac muscle cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060038 ! cardiac muscle cell proliferation relationship: negatively_regulates GO:0060038 ! cardiac muscle cell proliferation [Term] id: GO:0060045 name: positive regulation of cardiac muscle cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cardiac muscle cell proliferation." [GOC:dph, GOC:rph] synonym: "positive regulation of heart muscle cell proliferation" RELATED [] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0055023 ! positive regulation of cardiac muscle tissue growth is_a: GO:0060043 ! regulation of cardiac muscle cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060038 ! cardiac muscle cell proliferation relationship: positively_regulates GO:0060038 ! cardiac muscle cell proliferation [Term] id: GO:0060047 name: heart contraction namespace: biological_process def: "The multicellular organismal process in which the heart decreases in volume in a characteristic way to propel blood through the body." [GOC:dph] synonym: "cardiac contraction" RELATED [] synonym: "heart beating" EXACT [] synonym: "hemolymph circulation" RELATED [] is_a: GO:0003015 ! heart process relationship: part_of GO:0008015 ! blood circulation [Term] id: GO:0060048 name: cardiac muscle contraction namespace: biological_process def: "Muscle contraction of cardiac muscle tissue." [GOC:dph] synonym: "heart muscle contraction" EXACT [] is_a: GO:0006941 ! striated muscle contraction intersection_of: GO:0006936 ! muscle contraction intersection_of: occurs_in UBERON:0001133 ! cardiac muscle tissue relationship: occurs_in UBERON:0001133 ! cardiac muscle tissue relationship: part_of GO:0060047 ! heart contraction [Term] id: GO:0060065 name: uterus development namespace: biological_process def: "The reproductive developmental process whose specific outcome is the progression of the uterus over time, from its formation to the mature structure." [GOC:dph, GOC:ebc] synonym: "Mullerian tract development" RELATED [] is_a: GO:0048513 ! animal organ development is_a: GO:0048608 ! reproductive structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000995 ! uterus relationship: results_in_development_of UBERON:0000995 ! uterus [Term] id: GO:0060066 name: oviduct development namespace: biological_process def: "The reproductive developmental process whose specific outcome is the progression of an oviduct over time, from its formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism." [GOC:dph, GOC:ebc, http://www.thefreedictionary.com/oviduct] synonym: "fallopian tube development" NARROW [GOC:bf] synonym: "Mullerian tract development" RELATED [] is_a: GO:0035295 ! tube development is_a: GO:0048608 ! reproductive structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003889 ! fallopian tube relationship: results_in_development_of UBERON:0003889 ! fallopian tube [Term] id: GO:0060073 name: micturition namespace: biological_process def: "The regulation of body fluids process in which parasympathetic nerves stimulate the bladder wall muscle to contract and expel urine from the body." [GOC:dph] synonym: "urination" EXACT [] synonym: "urine voiding" EXACT [] xref: Wikipedia:Urination is_a: GO:0003014 ! renal system process is_a: GO:0007588 ! excretion [Term] id: GO:0060083 name: smooth muscle contraction involved in micturition namespace: biological_process def: "The process leading to shortening and/or development of tension in the urinary bladder smooth muscle tissue involved in the expulsion urine from the body." [GOC:dph, PMID:15827347] synonym: "smooth muscle contraction involved in urination" RELATED [] synonym: "urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:dph] is_a: GO:0014832 ! urinary bladder smooth muscle contraction intersection_of: GO:0006939 ! smooth muscle contraction intersection_of: part_of GO:0060073 ! micturition relationship: part_of GO:0060073 ! micturition [Term] id: GO:0060084 name: synaptic transmission involved in micturition namespace: biological_process def: "The process of communication from a neuron to a smooth muscle in the bladder that contributes to the expulsion of urine from the body." [GOC:dph, PMID:15827347] synonym: "synaptic transmission involved in urination" RELATED [] is_a: GO:0007274 ! neuromuscular synaptic transmission intersection_of: GO:0007268 ! chemical synaptic transmission intersection_of: part_of GO:0060073 ! micturition relationship: part_of GO:0060073 ! micturition [Term] id: GO:0060096 name: serotonin secretion, neurotransmission namespace: biological_process def: "The regulated release of serotonin by a cell, in which released serotonin acts as a neurotransmitter." [GOC:dph] synonym: "serotonin release, neurotransmission" RELATED [GOC:tb] is_a: GO:0001820 ! serotonin secretion is_a: GO:0007269 ! neurotransmitter secretion intersection_of: GO:0007269 ! neurotransmitter secretion intersection_of: has_primary_input CHEBI:350546 ! serotonin(1+) [Term] id: GO:0060135 name: maternal process involved in female pregnancy namespace: biological_process def: "A reproductive process occurring in the mother that allows an embryo or fetus to develop within it." [GOC:dph] is_a: GO:0048609 ! multicellular organismal reproductive process relationship: part_of GO:0007565 ! female pregnancy [Term] id: GO:0060136 name: embryonic process involved in female pregnancy namespace: biological_process def: "A reproductive process occurring in the embryo or fetus that allows the embryo or fetus to develop within the mother." [GOC:dph] is_a: GO:0048609 ! multicellular organismal reproductive process intersection_of: GO:0022414 ! reproductive process intersection_of: part_of GO:0007565 ! female pregnancy intersection_of: part_of GO:0009790 ! embryo development relationship: part_of GO:0007565 ! female pregnancy relationship: part_of GO:0009792 ! embryo development ending in birth or egg hatching [Term] id: GO:0060142 name: regulation of syncytium formation by plasma membrane fusion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." [GOC:dph] is_a: GO:0050793 ! regulation of developmental process is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0000768 ! syncytium formation by plasma membrane fusion relationship: regulates GO:0000768 ! syncytium formation by plasma membrane fusion [Term] id: GO:0060143 name: positive regulation of syncytium formation by plasma membrane fusion namespace: biological_process def: "Any process that increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." [GOC:dph] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051130 ! positive regulation of cellular component organization is_a: GO:0060142 ! regulation of syncytium formation by plasma membrane fusion intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0000768 ! syncytium formation by plasma membrane fusion relationship: positively_regulates GO:0000768 ! syncytium formation by plasma membrane fusion [Term] id: GO:0060157 name: urinary bladder development namespace: biological_process def: "The process whose specific outcome is the progression of the urinary bladder over time, from its formation to the mature structure. The urinary bladder is an elastic, muscular sac situated in the anterior part of the pelvic cavity in which urine collects before excretion." [GOC:dph, GOC:ln, GOC:mr, PMID:11768524, PMID:18276178, PMID:538956] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001255 ! urinary bladder relationship: part_of GO:0072001 ! renal system development relationship: results_in_development_of UBERON:0001255 ! urinary bladder property_value: RO:0002161 NCBITaxon:8782 [Term] id: GO:0060170 name: ciliary membrane namespace: cellular_component alt_id: GO:0020017 def: "The portion of the plasma membrane surrounding a cilium." [GOC:cilia, GOC:dph, GOC:rph] comment: Note that cilia and eukaryotic flagella are deemed to be equivalent. synonym: "cilial membrane" EXACT [] synonym: "cilium membrane" EXACT [] synonym: "flagellar membrane" NARROW [] synonym: "flagellum membrane" NARROW [] is_a: GO:0031253 ! cell projection membrane is_a: GO:0098588 ! bounding membrane of organelle intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0005929 ! cilium relationship: bounding_layer_of GO:0005929 ! cilium relationship: part_of GO:0005929 ! cilium [Term] id: GO:0060173 name: limb development namespace: biological_process def: "The process whose specific outcome is the progression of a limb over time, from its formation to the mature structure. A limb is an appendage of an animal used for locomotion or grasping. Examples include legs, arms or some types of fin." [GOC:dgh, GOC:dph, PMID:11487378] synonym: "limb bud development" NARROW [GOC:dph] synonym: "paired limb/fin development" EXACT [] xref: Wikipedia:Limb_development is_a: GO:0048736 ! appendage development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004708 ! paired limb/fin relationship: results_in_development_of UBERON:0004708 ! paired limb/fin [Term] id: GO:0060214 name: endocardium formation namespace: biological_process def: "Formation of the endocardium of the heart. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers." [GOC:bf, GOC:dph, PMID:17722983] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0002165 ! endocardium relationship: part_of GO:0003160 ! endocardium morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0002165 ! endocardium [Term] id: GO:0060218 name: hematopoietic stem cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a hematopoietic stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [GOC:bf, GOC:BHF, GOC:dph, GOC:rl, PMID:15378083] synonym: "haematopoietic stem cell differentiation" EXACT [] synonym: "haemopoietic stem cell differentiation" EXACT [] synonym: "hemopoietic stem cell differentiation" EXACT [] is_a: GO:0002244 ! hematopoietic progenitor cell differentiation is_a: GO:0048863 ! stem cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000037 ! hematopoietic stem cell relationship: results_in_acquisition_of_features_of CL:0000037 ! hematopoietic stem cell [Term] id: GO:0060219 name: camera-type eye photoreceptor cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell in a camera-type eye." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0001754 ! eye photoreceptor cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0010009 ! camera-type eye photoreceptor cell relationship: part_of GO:0003407 ! neural retina development relationship: part_of GO:0060042 ! retina morphogenesis in camera-type eye relationship: results_in_acquisition_of_features_of CL:0010009 ! camera-type eye photoreceptor cell [Term] id: GO:0060221 name: retinal rod cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized features of a retinal rod cell." [GOC:dph] is_a: GO:0060219 ! camera-type eye photoreceptor cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000604 ! retinal rod cell relationship: results_in_acquisition_of_features_of CL:0000604 ! retinal rod cell [Term] id: GO:0060231 name: mesenchymal to epithelial transition namespace: biological_process def: "A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell." [GOC:ascb_2009, GOC:dph, GOC:tb] synonym: "epithelial cell differentiation from mesenchymal cell" EXACT [GOC:BHF, GOC:dph, GOC:rl] synonym: "mesenchymal-epithelial transition" EXACT [GOC:dph] is_a: GO:0030855 ! epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: has_primary_input CL:0008019 ! mesenchymal cell intersection_of: results_in_acquisition_of_features_of CL:0000066 ! epithelial cell relationship: has_primary_input CL:0008019 ! mesenchymal cell [Term] id: GO:0060251 name: regulation of glial cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of glial cell proliferation." [GOC:dph, GOC:tb] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0014009 ! glial cell proliferation relationship: regulates GO:0014009 ! glial cell proliferation [Term] id: GO:0060252 name: positive regulation of glial cell proliferation namespace: biological_process def: "Any process that activates or increases the rate or extent of glial cell proliferation." [GOC:dph, GOC:sl, GOC:tb] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0014015 ! positive regulation of gliogenesis is_a: GO:0060251 ! regulation of glial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0014009 ! glial cell proliferation relationship: positively_regulates GO:0014009 ! glial cell proliferation [Term] id: GO:0060253 name: negative regulation of glial cell proliferation namespace: biological_process def: "Any process that stops or decreases the rate or extent of glial cell proliferation." [GOC:dph, GOC:sl, GOC:tb] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0014014 ! negative regulation of gliogenesis is_a: GO:0060251 ! regulation of glial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0014009 ! glial cell proliferation relationship: negatively_regulates GO:0014009 ! glial cell proliferation [Term] id: GO:0060255 name: regulation of macromolecule metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:dph, GOC:tb] is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0043170 ! macromolecule metabolic process relationship: regulates GO:0043170 ! macromolecule metabolic process [Term] id: GO:0060271 name: cilium assembly namespace: biological_process alt_id: GO:0042384 def: "The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole." [GOC:BHF, GOC:cilia, GOC:dph, GOC:kmv, GOC:pr, GOC:vw, ISBN:0198506732, PMID:13978319, PMID:27350441, Reactome:R-HSA-5617833.2] comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. synonym: "ciliogenesis" EXACT [] synonym: "cilium biogenesis" RELATED [GOC:mah] synonym: "cilium formation" EXACT [] synonym: "cilium morphogenesis" RELATED [] synonym: "cilium organization" RELATED [GOC:dph] synonym: "microtubule-based flagellum assembly" EXACT [] xref: Reactome:R-HSA-5617833.2 is_a: GO:0044782 ! cilium organization is_a: GO:0070925 ! organelle assembly is_a: GO:0120031 ! plasma membrane bounded cell projection assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0005929 ! cilium relationship: has_part GO:0035082 ! axoneme assembly relationship: has_part GO:0035735 ! intraciliary transport involved in cilium assembly relationship: has_part GO:0061512 ! protein localization to cilium relationship: has_part GO:0097712 ! vesicle targeting, trans-Golgi to periciliary membrane compartment relationship: has_part GO:1905349 ! ciliary transition zone assembly relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota relationship: results_in_assembly_of GO:0005929 ! cilium relationship: starts_with GO:0097711 ! ciliary basal body-plasma membrane docking property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3312 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4890 property_value: RO:0002161 NCBITaxon:5782 [Term] id: GO:0060281 name: regulation of oocyte development namespace: biological_process def: "Any process that modulates the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." [GOC:dph, GOC:tb, PMID:2394318] is_a: GO:1905879 ! regulation of oogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048599 ! oocyte development relationship: regulates GO:0048599 ! oocyte development [Term] id: GO:0060282 name: positive regulation of oocyte development namespace: biological_process def: "Any process that increases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." [GOC:dph, GOC:tb] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0060281 ! regulation of oocyte development is_a: GO:2000243 ! positive regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048599 ! oocyte development relationship: positively_regulates GO:0048599 ! oocyte development [Term] id: GO:0060283 name: negative regulation of oocyte development namespace: biological_process def: "Any process that decreases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." [GOC:dph, GOC:tb] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0060281 ! regulation of oocyte development is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048599 ! oocyte development relationship: negatively_regulates GO:0048599 ! oocyte development [Term] id: GO:0060284 name: regulation of cell development namespace: biological_process def: "Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." [GOC:dph, GOC:tb] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048468 ! cell development relationship: regulates GO:0048468 ! cell development [Term] id: GO:0060285 name: cilium-dependent cell motility namespace: biological_process alt_id: GO:0071974 def: "Cell motility due to the motion of one or more eukaryotic cilia. A eukaryotic cilium is a specialized organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole." [GOC:cilia, GOC:dgh, GOC:dph, GOC:krc, GOC:mlg, GOC:mtg_cambridge_2013] comment: Note that we deem eukaryotic cilia and microtubule-based flagella to be equivalent. synonym: "ciliary cell motility" RELATED [] synonym: "cilium cell motility" EXACT [] synonym: "microtubule-based flagellar cell motility" EXACT [] is_a: GO:0001539 ! cilium or flagellum-dependent cell motility relationship: has_part GO:0003341 ! cilium movement [Term] id: GO:0060294 name: cilium movement involved in cell motility namespace: biological_process def: "Movement of cilia mediated by motor proteins that contributes to the movement of a cell." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0003341 ! cilium movement intersection_of: GO:0003341 ! cilium movement intersection_of: part_of GO:0048870 ! cell motility relationship: part_of GO:0060285 ! cilium-dependent cell motility [Term] id: GO:0060295 name: regulation of cilium movement involved in cell motility namespace: biological_process def: "Any process that modulates the rate frequency or extent of cilium movement involved in ciliary motility." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0003352 ! regulation of cilium movement is_a: GO:1902019 ! regulation of cilium-dependent cell motility intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060294 ! cilium movement involved in cell motility relationship: regulates GO:0060294 ! cilium movement involved in cell motility [Term] id: GO:0060297 name: regulation of sarcomere organization namespace: biological_process def: "Any process that modulates the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." [GOC:BHF, GOC:dph, GOC:tb] synonym: "regulation of sarcomere organisation" EXACT [GOC:mah] is_a: GO:0110020 ! regulation of actomyosin structure organization is_a: GO:1902903 ! regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0045214 ! sarcomere organization relationship: regulates GO:0045214 ! sarcomere organization [Term] id: GO:0060298 name: positive regulation of sarcomere organization namespace: biological_process def: "Any process that increases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." [GOC:BHF, GOC:dph, GOC:tb] synonym: "positive regulation of sarcomere organisation" EXACT [GOC:mah] is_a: GO:0051155 ! positive regulation of striated muscle cell differentiation is_a: GO:0051495 ! positive regulation of cytoskeleton organization is_a: GO:0060297 ! regulation of sarcomere organization is_a: GO:1902905 ! positive regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0045214 ! sarcomere organization relationship: positively_regulates GO:0045214 ! sarcomere organization [Term] id: GO:0060299 name: negative regulation of sarcomere organization namespace: biological_process def: "Any process that decreases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." [GOC:BHF, GOC:dph, GOC:tb] synonym: "negative regulation of sarcomere organisation" EXACT [GOC:mah] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0051494 ! negative regulation of cytoskeleton organization is_a: GO:0060297 ! regulation of sarcomere organization is_a: GO:1902116 ! negative regulation of organelle assembly is_a: GO:1902904 ! negative regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0045214 ! sarcomere organization relationship: negatively_regulates GO:0045214 ! sarcomere organization [Term] id: GO:0060322 name: head development namespace: biological_process def: "The biological process whose specific outcome is the progression of a head from an initial condition to its mature state. The head is the anterior-most division of the body." [GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000033 ! head relationship: results_in_development_of UBERON:0000033 ! head [Term] id: GO:0060323 name: head morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the head are generated and organized. The head is the anterior-most division of the body." [GOC:dph] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000033 ! head relationship: part_of GO:0010171 ! body morphogenesis relationship: part_of GO:0060322 ! head development relationship: results_in_morphogenesis_of UBERON:0000033 ! head [Term] id: GO:0060324 name: face development namespace: biological_process def: "The biological process whose specific outcome is the progression of a face from an initial condition to its mature state. The face is the ventral division of the head." [GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001456 ! face relationship: part_of GO:0060322 ! head development relationship: results_in_development_of UBERON:0001456 ! face [Term] id: GO:0060325 name: face morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the face are generated and organized. The face is the ventral division of the head." [GOC:dph] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001456 ! face relationship: part_of GO:0060323 ! head morphogenesis relationship: part_of GO:0060324 ! face development relationship: results_in_morphogenesis_of UBERON:0001456 ! face [Term] id: GO:0060341 name: regulation of cellular localization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a process in which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell." [GOC:dph, GOC:tb] synonym: "regulation of cellular localisation" EXACT [GOC:mah] is_a: GO:0032879 ! regulation of localization is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0051641 ! cellular localization relationship: regulates GO:0051641 ! cellular localization [Term] id: GO:0060343 name: trabecula formation namespace: biological_process def: "The process of creating a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue." [GOC:dph] synonym: "trabecula biogenesis" RELATED [GOC:dph] synonym: "trabeculation" EXACT [GOC:dph] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0000440 ! trabecula relationship: part_of GO:0009887 ! animal organ morphogenesis relationship: part_of GO:0061383 ! trabecula morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0000440 ! trabecula [Term] id: GO:0060344 name: liver trabecula formation namespace: biological_process def: "The process of creating a trabecula in the liver. A trabecula is a tissue element in the form of a small beam, strut or rod." [GOC:dph] synonym: "liver trabecula biogenesis" RELATED [] synonym: "liver trabeculation" EXACT [GOC:dph] is_a: GO:0060343 ! trabecula formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0010183 ! liver trabecula relationship: part_of GO:0001889 ! liver development relationship: results_in_formation_of_anatomical_entity UBERON:0010183 ! liver trabecula [Term] id: GO:0060345 name: spleen trabecula formation namespace: biological_process def: "The process of creating a trabecula in the spleen. A trabecula is a tissue element in the form of a small beam, strut or rod." [GOC:dph] synonym: "spleen trabecula biogenesis" RELATED [GOC:dph] synonym: "spleen trabeculation" EXACT [GOC:dph] is_a: GO:0060343 ! trabecula formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0001265 ! trabecula of spleen relationship: part_of GO:0048536 ! spleen development relationship: results_in_formation_of_anatomical_entity UBERON:0001265 ! trabecula of spleen [Term] id: GO:0060347 name: heart trabecula formation namespace: biological_process def: "The process of creating a trabecula in the heart. A trabecula is a tissue element in the form of a small beam, strut or rod." [GOC:dph] synonym: "cardiac trabecula formation" EXACT [GOC:dph] synonym: "cardiac trabeculation" EXACT [GOC:dph] synonym: "heart trabecula biogenesis" RELATED [GOC:dph] synonym: "heart trabeculation" EXACT [GOC:dph] is_a: GO:0060343 ! trabecula formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0002511 ! trabecula carnea relationship: part_of GO:0003206 ! cardiac chamber morphogenesis relationship: part_of GO:0061384 ! heart trabecula morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0002511 ! trabecula carnea [Term] id: GO:0060348 name: bone development namespace: biological_process def: "The process whose specific outcome is the progression of bone over time, from its formation to the mature structure. Bone is the hard skeletal connective tissue consisting of both mineral and cellular components." [GOC:dph] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048513 ! animal organ development intersection_of: results_in_development_of UBERON:0001474 ! bone element relationship: part_of GO:0001501 ! skeletal system development relationship: results_in_development_of UBERON:0001474 ! bone element [Term] id: GO:0060349 name: bone morphogenesis namespace: biological_process def: "The process in which bones are generated and organized." [GOC:dph] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001474 ! bone element relationship: part_of GO:0048705 ! skeletal system morphogenesis relationship: part_of GO:0060348 ! bone development relationship: results_in_morphogenesis_of UBERON:0001474 ! bone element [Term] id: GO:0060350 name: endochondral bone morphogenesis namespace: biological_process def: "The process in which bones are generated and organized as a result of the conversion of initial cartilaginous anlage into bone." [GOC:dph, PMID:11680679] is_a: GO:0060349 ! bone morphogenesis intersection_of: GO:0060349 ! bone morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002513 ! endochondral bone relationship: results_in_morphogenesis_of UBERON:0002513 ! endochondral bone [Term] id: GO:0060351 name: cartilage development involved in endochondral bone morphogenesis namespace: biological_process def: "The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones." [GOC:dph] is_a: GO:0051216 ! cartilage development intersection_of: GO:0051216 ! cartilage development intersection_of: part_of GO:0060350 ! endochondral bone morphogenesis relationship: part_of GO:0060350 ! endochondral bone morphogenesis [Term] id: GO:0060359 name: response to ammonium ion namespace: biological_process alt_id: GO:1903717 def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:23509267] synonym: "response to ammonia" EXACT [] is_a: GO:0010035 ! response to inorganic substance is_a: GO:1901698 ! response to nitrogen compound intersection_of: GO:0050896 ! response to stimulus intersection_of: has_primary_input CHEBI:28938 ! ammonium relationship: has_primary_input CHEBI:28938 ! ammonium [Term] id: GO:0060379 name: cardiac muscle cell myoblast differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a cardiac myoblast. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life." [GOC:dph, GOC:tb] synonym: "cardiac myoblast differentiation" RELATED [GOC:dph, GOC:tb] synonym: "myocardial precursor cell differentiation" EXACT [GOC:mtg_heart] is_a: GO:0010002 ! cardioblast differentiation is_a: GO:0045445 ! myoblast differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000513 ! cardiac muscle myoblast relationship: results_in_acquisition_of_features_of CL:0000513 ! cardiac muscle myoblast [Term] id: GO:0060404 name: axonemal microtubule depolymerization namespace: biological_process def: "The removal of tubulin heterodimers from one or both ends of an axonemal microtubule. An axonemal microtubule is a microtubule in the axoneme of a cilium or flagellum; an axoneme contains nine modified doublet microtubules surrounding a pair of single microtubules." [GOC:cilia, GOC:dph, GOC:krc, GOC:tb] is_a: GO:0010938 ! cytoplasmic microtubule depolymerization is_a: GO:0061523 ! cilium disassembly intersection_of: GO:0007019 ! microtubule depolymerization intersection_of: occurs_in GO:0005930 ! axoneme relationship: occurs_in GO:0005930 ! axoneme [Term] id: GO:0060408 name: regulation of acetylcholine metabolic process namespace: biological_process def: "Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." [GOC:dph, GOC:tb] is_a: GO:0033238 ! regulation of amine metabolic process is_a: GO:0080090 ! regulation of primary metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0008291 ! acetylcholine metabolic process relationship: regulates GO:0008291 ! acetylcholine metabolic process [Term] id: GO:0060409 name: positive regulation of acetylcholine metabolic process namespace: biological_process def: "Any process that increases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." [GOC:dph, GOC:tb] is_a: GO:0033240 ! positive regulation of amine metabolic process is_a: GO:0060408 ! regulation of acetylcholine metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0008291 ! acetylcholine metabolic process relationship: positively_regulates GO:0008291 ! acetylcholine metabolic process [Term] id: GO:0060410 name: negative regulation of acetylcholine metabolic process namespace: biological_process def: "Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." [GOC:dph, GOC:tb] is_a: GO:0033239 ! negative regulation of amine metabolic process is_a: GO:0060408 ! regulation of acetylcholine metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0008291 ! acetylcholine metabolic process relationship: negatively_regulates GO:0008291 ! acetylcholine metabolic process [Term] id: GO:0060411 name: cardiac septum morphogenesis namespace: biological_process alt_id: GO:0003280 def: "The process in which the anatomical structure of a cardiac septum is generated and organized. A cardiac septum is a partition that separates parts of the heart." [GOC:dph, GOC:mtg_heart] synonym: "heart septum morphogenesis" EXACT [] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002099 ! cardiac septum relationship: part_of GO:0003206 ! cardiac chamber morphogenesis relationship: part_of GO:0003279 ! cardiac septum development relationship: results_in_morphogenesis_of UBERON:0002099 ! cardiac septum [Term] id: GO:0060412 name: ventricular septum morphogenesis namespace: biological_process def: "The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another." [GOC:dph] synonym: "interventricular septum morphogenesis" EXACT [GOC:dph] is_a: GO:0060411 ! cardiac septum morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002094 ! interventricular septum relationship: part_of GO:0003281 ! ventricular septum development relationship: results_in_morphogenesis_of UBERON:0002094 ! interventricular septum [Term] id: GO:0060413 name: atrial septum morphogenesis namespace: biological_process alt_id: GO:0003287 def: "The developmental process in which atrial septum is generated and organized. The atrial septum separates the upper chambers (the atria) of the heart from one another." [GOC:dph, GOC:mtg_heart] synonym: "interatrial septum morphogenesis" EXACT [GOC:dph] is_a: GO:0060411 ! cardiac septum morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002085 ! interatrial septum relationship: part_of GO:0003209 ! cardiac atrium morphogenesis relationship: part_of GO:0003283 ! atrial septum development relationship: results_in_morphogenesis_of UBERON:0002085 ! interatrial septum [Term] id: GO:0060414 name: aorta smooth muscle tissue morphogenesis namespace: biological_process def: "The process in which the structure of the smooth muscle tissue surrounding the aorta is generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body." [GOC:bf, GOC:dgh, GOC:dph, Wikipedia:Aorta] is_a: GO:0060415 ! muscle tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0004178 ! aorta smooth muscle tissue relationship: part_of GO:0035909 ! aorta morphogenesis relationship: part_of GO:0048745 ! smooth muscle tissue development relationship: results_in_morphogenesis_of UBERON:0004178 ! aorta smooth muscle tissue [Term] id: GO:0060415 name: muscle tissue morphogenesis namespace: biological_process def: "The process in which the anatomical structures of muscle tissue are generated and organized. Muscle tissue consists of a set of cells that are part of an organ and carry out a contractive function." [GOC:dph] is_a: GO:0048729 ! tissue morphogenesis intersection_of: GO:0048729 ! tissue morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002385 ! muscle tissue relationship: part_of GO:0048644 ! muscle organ morphogenesis relationship: results_in_morphogenesis_of UBERON:0002385 ! muscle tissue [Term] id: GO:0060419 name: heart growth namespace: biological_process def: "The increase in size or mass of the heart." [GOC:dph, GOC:tb] is_a: GO:0035265 ! organ growth intersection_of: GO:0048589 ! developmental growth intersection_of: results_in_growth_of UBERON:0000948 ! heart relationship: part_of GO:0007507 ! heart development relationship: results_in_growth_of UBERON:0000948 ! heart [Term] id: GO:0060420 name: regulation of heart growth namespace: biological_process def: "Any process that modulates the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart." [GOC:dph, GOC:tb] is_a: GO:0046620 ! regulation of organ growth is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060419 ! heart growth relationship: regulates GO:0060419 ! heart growth [Term] id: GO:0060421 name: positive regulation of heart growth namespace: biological_process def: "Any process that increases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0046622 ! positive regulation of organ growth is_a: GO:0060420 ! regulation of heart growth intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060419 ! heart growth relationship: positively_regulates GO:0060419 ! heart growth [Term] id: GO:0060425 name: lung morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the lung are generated and organized." [GOC:dph] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002048 ! lung relationship: part_of GO:0030324 ! lung development relationship: results_in_morphogenesis_of UBERON:0002048 ! lung [Term] id: GO:0060426 name: lung vasculature development namespace: biological_process def: "The biological process whose specific outcome is the progression of a lung vasculature from an initial condition to its mature state. This process begins with the formation of the lung vasculature and ends with the mature structure. The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs." [GOC:dph, GOC:mtg_lung] synonym: "pulmonary vasculature development" EXACT [GOC:dph, GOC:mtg_lung] is_a: GO:0001944 ! vasculature development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000102 ! lung vasculature relationship: part_of GO:0030324 ! lung development relationship: results_in_development_of UBERON:0000102 ! lung vasculature [Term] id: GO:0060427 name: lung connective tissue development namespace: biological_process def: "The biological process whose specific outcome is the progression of lung connective tissue from an initial condition to its mature state. This process begins with the formation of lung connective tissue and ends with the mature structure. The lung connective tissue is a material made up of fibers forming a framework and support structure for the lungs." [GOC:dph, GOC:mtg_lung] synonym: "pulmonary connective tissue development" EXACT [] is_a: GO:0061448 ! connective tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000114 ! lung connective tissue relationship: part_of GO:0030324 ! lung development relationship: results_in_development_of UBERON:0000114 ! lung connective tissue [Term] id: GO:0060428 name: lung epithelium development namespace: biological_process def: "The biological process whose specific outcome is the progression of the lung epithelium from an initial condition to its mature state. This process begins with the formation of lung epithelium and ends with the mature structure. The lung epithelium is the specialized epithelium that lines the inside of the lung." [GOC:dph, GOC:mtg_lung] synonym: "pulmonary epithelium development" EXACT [GOC:dph, GOC:mtg_lung] is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000115 ! lung epithelium relationship: part_of GO:0030324 ! lung development relationship: results_in_development_of UBERON:0000115 ! lung epithelium [Term] id: GO:0060429 name: epithelium development namespace: biological_process def: "The process whose specific outcome is the progression of an epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure." [GOC:dph, GOC:mtg_lung] subset: goslim_drosophila is_a: GO:0009888 ! tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000483 ! epithelium relationship: results_in_development_of UBERON:0000483 ! epithelium [Term] id: GO:0060431 name: primary lung bud formation namespace: biological_process def: "The morphogenetic process in which the foregut region specified to become the lung forms the initial left and right buds." [GOC:dph, GOC:mtg_lung] synonym: "lung formation" EXACT [GOC:dph] is_a: GO:0016331 ! morphogenesis of embryonic epithelium is_a: GO:0048645 ! animal organ formation is_a: GO:0060441 ! epithelial tube branching involved in lung morphogenesis is_a: GO:0060572 ! morphogenesis of an epithelial bud intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0002048 ! lung relationship: results_in_formation_of_anatomical_entity UBERON:0002048 ! lung [Term] id: GO:0060437 name: lung growth namespace: biological_process def: "The increase in size or mass of a lung. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax." [GOC:dph] is_a: GO:0035265 ! organ growth intersection_of: GO:0048589 ! developmental growth intersection_of: results_in_growth_of UBERON:0002048 ! lung relationship: part_of GO:0030324 ! lung development relationship: results_in_growth_of UBERON:0002048 ! lung [Term] id: GO:0060438 name: trachea development namespace: biological_process def: "The process whose specific outcome is the progression of a trachea over time, from its formation to the mature structure. The trachea is the portion of the airway that attaches to the bronchi as it branches." [GOC:dph] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001005 ! respiratory airway relationship: part_of GO:0060541 ! respiratory system development relationship: results_in_development_of UBERON:0001005 ! respiratory airway [Term] id: GO:0060439 name: trachea morphogenesis namespace: biological_process def: "The process in which a trachea is generated and organized. The trachea is the portion of the airway that attaches to the bronchi as it branches." [GOC:dph] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001005 ! respiratory airway relationship: part_of GO:0060438 ! trachea development relationship: results_in_morphogenesis_of UBERON:0001005 ! respiratory airway [Term] id: GO:0060440 name: trachea formation namespace: biological_process def: "The process pertaining to the initial formation of a trachea from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the trachea is recognizable. The trachea is the portion of the airway that attaches to the bronchi as it branches." [GOC:dph] is_a: GO:0048645 ! animal organ formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0001005 ! respiratory airway relationship: part_of GO:0060439 ! trachea morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0001005 ! respiratory airway [Term] id: GO:0060441 name: epithelial tube branching involved in lung morphogenesis namespace: biological_process def: "The process in which a highly ordered sequence of patterning events generates the branched epithelial tubes of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units." [GOC:dph, GOC:mtg_lung] synonym: "lung branching morphogenesis" EXACT [GOC:dph] is_a: GO:0048754 ! branching morphogenesis of an epithelial tube intersection_of: GO:0048754 ! branching morphogenesis of an epithelial tube intersection_of: part_of GO:0060425 ! lung morphogenesis relationship: part_of GO:0060425 ! lung morphogenesis [Term] id: GO:0060450 name: positive regulation of hindgut contraction namespace: biological_process def: "Any process that increases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine." [GOC:dph, GOC:tb] is_a: GO:0043134 ! regulation of hindgut contraction is_a: GO:0045987 ! positive regulation of smooth muscle contraction is_a: GO:0060456 ! positive regulation of digestive system process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0043133 ! hindgut contraction relationship: positively_regulates GO:0043133 ! hindgut contraction [Term] id: GO:0060451 name: negative regulation of hindgut contraction namespace: biological_process def: "Any process that decreases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine." [GOC:dph, GOC:tb] is_a: GO:0043134 ! regulation of hindgut contraction is_a: GO:0045986 ! negative regulation of smooth muscle contraction is_a: GO:0060457 ! negative regulation of digestive system process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0043133 ! hindgut contraction relationship: negatively_regulates GO:0043133 ! hindgut contraction [Term] id: GO:0060452 name: positive regulation of cardiac muscle contraction namespace: biological_process def: "Any process that increases the frequency, rate or extent of cardiac muscle contraction." [GOC:dph, GOC:tb] is_a: GO:0045823 ! positive regulation of heart contraction is_a: GO:0045989 ! positive regulation of striated muscle contraction is_a: GO:0055117 ! regulation of cardiac muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060048 ! cardiac muscle contraction relationship: positively_regulates GO:0060048 ! cardiac muscle contraction [Term] id: GO:0060453 name: regulation of gastric acid secretion namespace: biological_process def: "Any process that modulates the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion." [GOC:dph, GOC:tb] is_a: GO:0044058 ! regulation of digestive system process is_a: GO:0051046 ! regulation of secretion intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001696 ! gastric acid secretion relationship: regulates GO:0001696 ! gastric acid secretion [Term] id: GO:0060454 name: positive regulation of gastric acid secretion namespace: biological_process def: "Any process that increases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion." [GOC:dph, GOC:tb] is_a: GO:0051047 ! positive regulation of secretion is_a: GO:0060453 ! regulation of gastric acid secretion is_a: GO:0060456 ! positive regulation of digestive system process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001696 ! gastric acid secretion relationship: positively_regulates GO:0001696 ! gastric acid secretion [Term] id: GO:0060455 name: negative regulation of gastric acid secretion namespace: biological_process def: "Any process that decreases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion." [GOC:dph, GOC:tb] is_a: GO:0051048 ! negative regulation of secretion is_a: GO:0060453 ! regulation of gastric acid secretion is_a: GO:0060457 ! negative regulation of digestive system process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001696 ! gastric acid secretion relationship: negatively_regulates GO:0001696 ! gastric acid secretion [Term] id: GO:0060456 name: positive regulation of digestive system process namespace: biological_process def: "Any process that increases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." [GOC:dph, GOC:tb] is_a: GO:0044058 ! regulation of digestive system process is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0022600 ! digestive system process relationship: positively_regulates GO:0022600 ! digestive system process [Term] id: GO:0060457 name: negative regulation of digestive system process namespace: biological_process def: "Any process that decreases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." [GOC:dph, GOC:tb] is_a: GO:0044058 ! regulation of digestive system process is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0022600 ! digestive system process relationship: negatively_regulates GO:0022600 ! digestive system process [Term] id: GO:0060458 name: right lung development namespace: biological_process def: "The biological process whose specific outcome is the progression of a right lung from an initial condition to its mature state. This process begins with the formation of the right lung and ends with the mature structure. The right lung is the lung which is on the right side of the anterior posterior axis looking from a dorsal to ventral aspect." [GOC:dph, GOC:mtg_lung] synonym: "right pulmonary development" EXACT [GOC:dph, GOC:mtg_lung] is_a: GO:0030324 ! lung development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002167 ! right lung relationship: results_in_development_of UBERON:0002167 ! right lung [Term] id: GO:0060459 name: left lung development namespace: biological_process def: "The biological process whose specific outcome is the progression of a left lung from an initial condition to its mature state. This process begins with the formation of the left lung and ends with the mature structure. The left lung is the lung which is on the left side of the anterior posterior axis looking from a dorsal to ventral aspect." [GOC:dph, GOC:mtg_lung] synonym: "left pulmonary development" EXACT [GOC:dph] is_a: GO:0030324 ! lung development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002168 ! left lung relationship: results_in_development_of UBERON:0002168 ! left lung [Term] id: GO:0060460 name: left lung morphogenesis namespace: biological_process def: "The process in which anatomical structures of the left lung are generated and organized." [GOC:dph] is_a: GO:0060425 ! lung morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002168 ! left lung relationship: part_of GO:0060459 ! left lung development relationship: results_in_morphogenesis_of UBERON:0002168 ! left lung [Term] id: GO:0060461 name: right lung morphogenesis namespace: biological_process def: "The process in which anatomical structures of the right lung are generated and organized." [GOC:dph, GOC:mtg_lung] is_a: GO:0060425 ! lung morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002167 ! right lung relationship: part_of GO:0060458 ! right lung development relationship: results_in_morphogenesis_of UBERON:0002167 ! right lung [Term] id: GO:0060462 name: lung lobe development namespace: biological_process def: "The biological process whose specific outcome is the progression of a lung lobe from an initial condition to its mature state. This process begins with the formation of a lung lobe by branching morphogenesis and ends with the mature structure. A lung lobe is one of the rounded projections that compose the lung." [GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000101 ! lobe of lung relationship: part_of GO:0030324 ! lung development relationship: results_in_development_of UBERON:0000101 ! lobe of lung [Term] id: GO:0060463 name: lung lobe morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a lung lobe are generated and organized. A lung lobe is a projection that extends from the lung." [GOC:dph] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000101 ! lobe of lung relationship: part_of GO:0060425 ! lung morphogenesis relationship: part_of GO:0060462 ! lung lobe development relationship: results_in_morphogenesis_of UBERON:0000101 ! lobe of lung [Term] id: GO:0060464 name: lung lobe formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a lung lobe from unspecified parts. This process begins with the specific processes that contribute to the appearance of the lobe and ends when the structural rudiment is recognizable. A lung lobe is a projection that extends from the lung." [GOC:dph] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0000101 ! lobe of lung relationship: part_of GO:0060463 ! lung lobe morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0000101 ! lobe of lung [Term] id: GO:0060465 name: pharynx development namespace: biological_process def: "The biological process whose specific outcome is the progression of a pharynx from an initial condition to its mature state. The pharynx is the part of the digestive system immediately posterior to the mouth." [GOC:dph, GOC:rk] synonym: "pharyngeal development" RELATED [] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0006562 ! pharynx relationship: part_of GO:0048565 ! digestive tract development relationship: results_in_development_of UBERON:0006562 ! pharynx [Term] id: GO:0060467 name: negative regulation of fertilization namespace: biological_process def: "Any process that decreases the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy)." [GOC:dph] is_a: GO:0080154 ! regulation of fertilization is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0009566 ! fertilization relationship: negatively_regulates GO:0009566 ! fertilization [Term] id: GO:0060468 name: prevention of polyspermy namespace: biological_process def: "The negative regulation of fertilization process that takes place as part of egg activation, ensuring that only a single sperm fertilizes the egg." [GOC:dph] synonym: "negative regulation of fertilization involved in egg activation" EXACT [GOC:dph] synonym: "polyspermy block" EXACT [GOC:dph] is_a: GO:0022414 ! reproductive process is_a: GO:0060467 ! negative regulation of fertilization intersection_of: GO:0060467 ! negative regulation of fertilization intersection_of: part_of GO:0007343 ! egg activation relationship: part_of GO:0007343 ! egg activation [Term] id: GO:0060474 name: positive regulation of flagellated sperm motility involved in capacitation namespace: biological_process def: "The process in which the controlled movement of a flagellated sperm cell is initiated as part of the process required for flagellated sperm to reach fertilization competence." [GOC:cilia, GOC:dph, GOC:krc] synonym: "positive regulation of sperm motility involved in capacitation" RELATED [] is_a: GO:0022414 ! reproductive process is_a: GO:1902093 ! positive regulation of flagellated sperm motility intersection_of: GO:1902093 ! positive regulation of flagellated sperm motility intersection_of: part_of GO:0048240 ! sperm capacitation relationship: part_of GO:0048240 ! sperm capacitation [Term] id: GO:0060479 name: lung cell differentiation namespace: biological_process def: "The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GOC:dph, GOC:mtg_lung] synonym: "pulmonary cell differentiation" EXACT [GOC:dph] is_a: GO:0030154 ! cell differentiation relationship: part_of GO:0030324 ! lung development [Term] id: GO:0060485 name: mesenchyme development namespace: biological_process def: "The process whose specific outcome is the progression of a mesenchymal tissue over time, from its formation to the mature structure. A mesenchymal tissue is made up of loosely packed stellate cells." [GOC:dph] synonym: "mesenchymal development" EXACT [GOC:dph] is_a: GO:0009888 ! tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003104 ! mesenchyme relationship: part_of GO:0048513 ! animal organ development relationship: results_in_development_of UBERON:0003104 ! mesenchyme [Term] id: GO:0060487 name: lung epithelial cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell that contributes to the epithelium of the lung." [GOC:dph] synonym: "pulmonary epithelial cell differentiation" RELATED [GOC:dph] is_a: GO:0030855 ! epithelial cell differentiation is_a: GO:0060479 ! lung cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000082 ! epithelial cell of lung relationship: part_of GO:0060428 ! lung epithelium development relationship: results_in_acquisition_of_features_of CL:0000082 ! epithelial cell of lung [Term] id: GO:0060491 name: regulation of cell projection assembly namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of cell projection assembly." [GOC:dph, GOC:tb] synonym: "regulation of cell projection formation" RELATED [GOC:dph, GOC:tb] is_a: GO:0031344 ! regulation of cell projection organization is_a: GO:0044087 ! regulation of cellular component biogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030031 ! cell projection assembly relationship: regulates GO:0030031 ! cell projection assembly [Term] id: GO:0060495 name: cell-cell signaling involved in lung development namespace: biological_process def: "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the lung, from its initial state to the mature structure." [GOC:dph, GOC:mtg_lung] synonym: "cell-cell signalling involved in lung development" EXACT [GOC:mah] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: part_of GO:0030324 ! lung development relationship: part_of GO:0030324 ! lung development [Term] id: GO:0060496 name: mesenchymal-epithelial cell signaling involved in lung development namespace: biological_process def: "Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell and contributes to the development of the lung." [GOC:dph, GOC:mtg_lung] synonym: "mesenchymal-epithelial cell signalling involved in lung development" EXACT [GOC:mah] is_a: GO:0060495 ! cell-cell signaling involved in lung development is_a: GO:0060638 ! mesenchymal-epithelial cell signaling intersection_of: GO:0060638 ! mesenchymal-epithelial cell signaling intersection_of: part_of GO:0030324 ! lung development [Term] id: GO:0060497 name: mesenchymal-endodermal cell signaling namespace: biological_process def: "Any process that mediates the transfer of information between a mesenchymal cell and an endodermal cell." [GOC:dph] synonym: "mesenchymal-endodermal cell signalling" EXACT [GOC:mah] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: has_end_location CL:0000223 ! endodermal cell intersection_of: has_start_location CL:0008019 ! mesenchymal cell relationship: has_end_location CL:0000223 ! endodermal cell relationship: has_start_location CL:0008019 ! mesenchymal cell [Term] id: GO:0060501 name: positive regulation of epithelial cell proliferation involved in lung morphogenesis namespace: biological_process def: "Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung attaining its shape." [GOC:dph] is_a: GO:0050679 ! positive regulation of epithelial cell proliferation is_a: GO:2000794 ! regulation of epithelial cell proliferation involved in lung morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060502 ! epithelial cell proliferation involved in lung morphogenesis relationship: positively_regulates GO:0060502 ! epithelial cell proliferation involved in lung morphogenesis [Term] id: GO:0060502 name: epithelial cell proliferation involved in lung morphogenesis namespace: biological_process def: "The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the lung." [GOC:dph] is_a: GO:0050673 ! epithelial cell proliferation intersection_of: GO:0050673 ! epithelial cell proliferation intersection_of: part_of GO:0060425 ! lung morphogenesis relationship: part_of GO:0060425 ! lung morphogenesis relationship: part_of GO:0060428 ! lung epithelium development [Term] id: GO:0060536 name: cartilage morphogenesis namespace: biological_process def: "The process in which the anatomical structures of cartilage are generated and organized." [GOC:dph] is_a: GO:0009887 ! animal organ morphogenesis is_a: GO:0048729 ! tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0007844 ! cartilage element relationship: part_of GO:0051216 ! cartilage development relationship: results_in_morphogenesis_of UBERON:0007844 ! cartilage element created_by: dph creation_date: 2009-04-10T09:13:27Z [Term] id: GO:0060537 name: muscle tissue development namespace: biological_process def: "The progression of muscle tissue over time, from its initial formation to its mature state. Muscle tissue is a contractile tissue made up of actin and myosin fibers." [GOC:dph] is_a: GO:0009888 ! tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002385 ! muscle tissue relationship: results_in_development_of UBERON:0002385 ! muscle tissue created_by: dph creation_date: 2009-04-10T08:05:37Z [Term] id: GO:0060538 name: skeletal muscle organ development namespace: biological_process def: "The progression of a skeletal muscle organ over time from its initial formation to its mature state. A skeletal muscle organ includes the skeletal muscle tissue and its associated connective tissue." [GOC:dph] is_a: GO:0007517 ! muscle organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0014892 ! skeletal muscle organ, vertebrate relationship: results_in_development_of UBERON:0014892 ! skeletal muscle organ, vertebrate created_by: dph creation_date: 2009-04-10T08:25:12Z [Term] id: GO:0060539 name: diaphragm development namespace: biological_process def: "The progression of the diaphragm over time from its initial formation to the mature structure. The diaphragm is a skeletal muscle that is responsible for contraction and expansion of the lungs." [GOC:dph] is_a: GO:0060538 ! skeletal muscle organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001103 ! diaphragm relationship: part_of GO:0060541 ! respiratory system development relationship: results_in_development_of UBERON:0001103 ! diaphragm property_value: RO:0002161 NCBITaxon:8782 created_by: dph creation_date: 2009-04-10T08:44:56Z [Term] id: GO:0060540 name: diaphragm morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the diaphragm are generated and organized." [GOC:dph] is_a: GO:0048644 ! muscle organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001103 ! diaphragm relationship: part_of GO:0060539 ! diaphragm development relationship: results_in_morphogenesis_of UBERON:0001103 ! diaphragm property_value: RO:0002161 NCBITaxon:8782 created_by: dph creation_date: 2009-04-10T08:47:51Z [Term] id: GO:0060541 name: respiratory system development namespace: biological_process def: "The progression of the respiratory system over time from its formation to its mature structure. The respiratory system carries out respiratory gaseous exchange." [GOC:dph] subset: goslim_drosophila is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001004 ! respiratory system relationship: results_in_development_of UBERON:0001004 ! respiratory system created_by: dph creation_date: 2009-04-10T08:55:42Z [Term] id: GO:0060560 name: developmental growth involved in morphogenesis namespace: biological_process def: "The increase in size or mass of an anatomical structure that contributes to the structure attaining its shape." [GOC:dph] synonym: "differential growth" EXACT [GOC:dph] is_a: GO:0048589 ! developmental growth intersection_of: GO:0048589 ! developmental growth intersection_of: part_of GO:0009653 ! anatomical structure morphogenesis relationship: part_of GO:0009653 ! anatomical structure morphogenesis created_by: dph creation_date: 2009-04-28T08:42:53Z [Term] id: GO:0060561 name: apoptotic process involved in morphogenesis namespace: biological_process def: "Any apoptotic process that contributes to the shaping of an anatomical structure." [GOC:dph, GOC:mtg_apoptosis] synonym: "apoptosis involved in development" RELATED [] synonym: "apoptosis involved in morphogenesis" NARROW [] synonym: "morphogenetic apoptosis" RELATED [GOC:dph] is_a: GO:1902742 ! apoptotic process involved in development intersection_of: GO:0006915 ! apoptotic process intersection_of: part_of GO:0009653 ! anatomical structure morphogenesis relationship: part_of GO:0009653 ! anatomical structure morphogenesis created_by: dph creation_date: 2009-04-28T09:17:27Z [Term] id: GO:0060562 name: epithelial tube morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a tube are generated and organized from an epithelium. Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system." [GOC:dph] is_a: GO:0002009 ! morphogenesis of an epithelium is_a: GO:0035239 ! tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003914 ! epithelial tube relationship: results_in_morphogenesis_of UBERON:0003914 ! epithelial tube created_by: dph creation_date: 2009-04-28T09:33:36Z [Term] id: GO:0060563 name: neuroepithelial cell differentiation namespace: biological_process def: "The process in which epiblast cells acquire specialized features of neuroepithelial cells." [GOC:dph, GOC:tb] is_a: GO:0002065 ! columnar/cuboidal epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000710 ! neurecto-epithelial cell relationship: results_in_acquisition_of_features_of CL:0000710 ! neurecto-epithelial cell created_by: dph creation_date: 2009-04-29T01:50:05Z [Term] id: GO:0060571 name: morphogenesis of an epithelial fold namespace: biological_process def: "The morphogenetic process in which an epithelial sheet bends along a linear axis." [GOC:dph] synonym: "epithelial folding" EXACT [GOC:dph] synonym: "folding of an epithelial sheet" RELATED [GOC:dph] is_a: GO:0002009 ! morphogenesis of an epithelium intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0005157 ! epithelial fold relationship: results_in_morphogenesis_of UBERON:0005157 ! epithelial fold created_by: dph creation_date: 2009-04-30T09:27:17Z [Term] id: GO:0060572 name: morphogenesis of an epithelial bud namespace: biological_process def: "The morphogenetic process in which a bud forms from an epithelial sheet. A bud is a protrusion that forms form the sheet by localized folding." [GOC:dph] is_a: GO:0060571 ! morphogenesis of an epithelial fold intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0005153 ! epithelial bud relationship: results_in_morphogenesis_of UBERON:0005153 ! epithelial bud created_by: dph creation_date: 2009-04-30T09:38:35Z [Term] id: GO:0060574 name: intestinal epithelial cell maturation namespace: biological_process def: "The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell of the intestine to attain its fully functional state. A columnar/cuboidal epithelial cell of the intestine mature as they migrate from the intestinal crypt to the villus." [GOC:dph, PMID:18824147] is_a: GO:0002069 ! columnar/cuboidal epithelial cell maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of CL:0002563 ! intestinal epithelial cell relationship: part_of GO:0060576 ! intestinal epithelial cell development relationship: results_in_maturation_of CL:0002563 ! intestinal epithelial cell created_by: dph creation_date: 2009-05-06T08:10:41Z [Term] id: GO:0060575 name: intestinal epithelial cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell of the intestine." [GOC:dph] is_a: GO:0002065 ! columnar/cuboidal epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0002563 ! intestinal epithelial cell relationship: part_of GO:0048565 ! digestive tract development relationship: results_in_acquisition_of_features_of CL:0002563 ! intestinal epithelial cell created_by: dph creation_date: 2009-05-06T08:17:56Z [Term] id: GO:0060576 name: intestinal epithelial cell development namespace: biological_process def: "The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell of the intestine over time, from its formation to the mature structure." [GOC:dph] is_a: GO:0002066 ! columnar/cuboidal epithelial cell development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of CL:0002563 ! intestinal epithelial cell relationship: part_of GO:0060575 ! intestinal epithelial cell differentiation relationship: results_in_development_of CL:0002563 ! intestinal epithelial cell created_by: dph creation_date: 2009-05-06T08:20:24Z [Term] id: GO:0060577 name: pulmonary vein morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the pulmonary venous blood vessels are generated and organized. Pulmonary veins are blood vessels that transport blood from the lungs to the heart." [GOC:dph] synonym: "pulmonary venous blood vessel morphogenesis" RELATED [GOC:dph] is_a: GO:0048845 ! venous blood vessel morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002016 ! pulmonary vein relationship: results_in_morphogenesis_of UBERON:0002016 ! pulmonary vein created_by: dph creation_date: 2009-05-06T08:44:04Z [Term] id: GO:0060578 name: superior vena cava morphogenesis namespace: biological_process def: "The process in which the anatomical structure of superior vena cava generated and organized. The superior vena cava is a blood vessel that transports blood from the upper body to the heart." [GOC:dph] is_a: GO:0048845 ! venous blood vessel morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001585 ! anterior vena cava relationship: results_in_morphogenesis_of UBERON:0001585 ! anterior vena cava created_by: dph creation_date: 2009-05-06T08:47:21Z [Term] id: GO:0060581 name: cell fate commitment involved in pattern specification namespace: biological_process def: "The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells within a field of cells that will exhibit a certain pattern of differentiation. Positional information is established through protein signals that emanate from a localized source within a developmental field resulting in specification of a cell type. Those signals are then interpreted in a cell-autonomous manner resulting in the determination of the cell type." [GOC:dph] is_a: GO:0045165 ! cell fate commitment intersection_of: GO:0045165 ! cell fate commitment intersection_of: part_of GO:0007389 ! pattern specification process relationship: part_of GO:0007389 ! pattern specification process created_by: dph creation_date: 2009-05-07T12:40:55Z [Term] id: GO:0060591 name: chondroblast differentiation namespace: biological_process def: "The process in which a mesenchymal cell, acquires specialized structural and/or functional features of a chondroblast. Differentiation includes the processes involved in commitment of a cell to a chondroblast fate. A chondroblast is a precursor cell to chondrocytes." [GOC:dph] synonym: "chondrocyte progenitor cell differentiation" RELATED [GOC:dph] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000058 ! chondroblast relationship: part_of GO:0051216 ! cartilage development relationship: results_in_acquisition_of_features_of CL:0000058 ! chondroblast created_by: dph creation_date: 2009-05-11T07:47:36Z [Term] id: GO:0060612 name: adipose tissue development namespace: biological_process def: "The process whose specific outcome is the progression of adipose tissue over time, from its formation to the mature structure. Adipose tissue is specialized tissue that is used to store fat." [GOC:dph] synonym: "adipogenesis" RELATED [GOC:mah, GOC:sl] is_a: GO:0061448 ! connective tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001013 ! adipose tissue relationship: part_of GO:0048513 ! animal organ development relationship: results_in_development_of UBERON:0001013 ! adipose tissue created_by: dph creation_date: 2009-05-15T12:36:28Z [Term] id: GO:0060623 name: regulation of chromosome condensation namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of chromosome condensation, the progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells." [GOC:dph, GOC:tb] is_a: GO:0033044 ! regulation of chromosome organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030261 ! chromosome condensation relationship: regulates GO:0030261 ! chromosome condensation created_by: dph creation_date: 2009-05-18T02:12:13Z [Term] id: GO:0060627 name: regulation of vesicle-mediated transport namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell." [GOC:dph, GOC:tb] is_a: GO:0050794 ! regulation of cellular process is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0016192 ! vesicle-mediated transport relationship: regulates GO:0016192 ! vesicle-mediated transport created_by: dph creation_date: 2009-05-18T02:29:43Z [Term] id: GO:0060632 name: regulation of microtubule-based movement namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of microtubule-based movement, the movement of organelles, other microtubules and other particles along microtubules, mediated by motor proteins." [GOC:dph, GOC:tb] is_a: GO:0032886 ! regulation of microtubule-based process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007018 ! microtubule-based movement relationship: regulates GO:0007018 ! microtubule-based movement created_by: dph creation_date: 2009-05-18T03:07:02Z [Term] id: GO:0060638 name: mesenchymal-epithelial cell signaling namespace: biological_process def: "Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell where it is received and interpreted." [GOC:dph] synonym: "mesenchymal-epithelial cell signalling" EXACT [GOC:mah] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: has_end_location CL:0000066 ! epithelial cell intersection_of: has_start_location CL:0008019 ! mesenchymal cell relationship: has_end_location CL:0000066 ! epithelial cell relationship: has_start_location CL:0008019 ! mesenchymal cell created_by: dph creation_date: 2009-05-19T03:59:05Z [Term] id: GO:0060669 name: embryonic placenta morphogenesis namespace: biological_process def: "The process in which the embryonic placenta is generated and organized." [GOC:dph] is_a: GO:0048598 ! embryonic morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0007106 ! chorionic villus relationship: part_of GO:0001892 ! embryonic placenta development relationship: results_in_morphogenesis_of UBERON:0007106 ! chorionic villus created_by: dph creation_date: 2009-06-02T09:33:37Z [Term] id: GO:0060670 name: branching involved in labyrinthine layer morphogenesis namespace: biological_process def: "The process in which the branches of the fetal placental villi are generated and organized. The villous part of the placenta is called the labyrinth layer." [GOC:dph, PMID:16916377] is_a: GO:0048598 ! embryonic morphogenesis is_a: GO:0061138 ! morphogenesis of a branching epithelium intersection_of: GO:0061138 ! morphogenesis of a branching epithelium intersection_of: part_of GO:0060713 ! labyrinthine layer morphogenesis relationship: part_of GO:0060713 ! labyrinthine layer morphogenesis created_by: dph creation_date: 2009-06-02T10:40:40Z [Term] id: GO:0060671 name: epithelial cell differentiation involved in embryonic placenta development namespace: biological_process def: "The process in which a trophoblast cell acquires specialized features of an epithelial cell of the placental labyrinthine layer." [GOC:dph, PMID:16916377] is_a: GO:0030855 ! epithelial cell differentiation is_a: GO:0060706 ! cell differentiation involved in embryonic placenta development intersection_of: GO:0030855 ! epithelial cell differentiation intersection_of: part_of GO:0001892 ! embryonic placenta development relationship: part_of GO:0060711 ! labyrinthine layer development created_by: dph creation_date: 2009-06-02T11:40:52Z [Term] id: GO:0060673 name: cell-cell signaling involved in placenta development namespace: biological_process def: "Any process that mediates the transfer of information from one cell to another." [GOC:dph, PMID:16916377] synonym: "cell-cell signalling involved in placenta development" EXACT [GOC:mah] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: part_of GO:0001890 ! placenta development relationship: part_of GO:0001892 ! embryonic placenta development created_by: dph creation_date: 2009-06-02T12:58:03Z [Term] id: GO:0060674 name: placenta blood vessel development namespace: biological_process def: "The process whose specific outcome is the progression of a blood vessel of the placenta over time, from its formation to the mature structure." [GOC:dph, PMID:16916377] is_a: GO:0001568 ! blood vessel development relationship: part_of GO:0001890 ! placenta development created_by: dph creation_date: 2009-06-02T01:09:43Z [Term] id: GO:0060675 name: ureteric bud morphogenesis namespace: biological_process def: "The process in which the ureteric bud is generated and organized." [GOC:dph, GOC:mtg_kidney_jan10] is_a: GO:0072171 ! mesonephric tubule morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000084 ! ureteric bud relationship: part_of GO:0001657 ! ureteric bud development relationship: results_in_morphogenesis_of UBERON:0000084 ! ureteric bud created_by: dph creation_date: 2009-06-02T01:31:41Z [Term] id: GO:0060676 name: ureteric bud formation namespace: biological_process def: "The developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct. This process begins when the bud protrudes from the duct and ends when it is a recognizable bud." [GOC:dph, PMID:16916378] is_a: GO:0072172 ! mesonephric tubule formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0000084 ! ureteric bud relationship: part_of GO:0060675 ! ureteric bud morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0000084 ! ureteric bud created_by: dph creation_date: 2009-06-02T01:47:23Z [Term] id: GO:0060684 name: epithelial-mesenchymal cell signaling namespace: biological_process def: "Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell where it is interpreted." [GOC:dph] synonym: "epithelial-mesenchymal cell signalling" EXACT [GOC:mah] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: has_end_location CL:0008019 ! mesenchymal cell intersection_of: has_start_location CL:0000066 ! epithelial cell relationship: has_end_location CL:0008019 ! mesenchymal cell relationship: has_start_location CL:0000066 ! epithelial cell created_by: dph creation_date: 2009-06-03T06:36:46Z [Term] id: GO:0060688 name: regulation of morphogenesis of a branching structure namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of branching morphogenesis, the process in which the anatomical structures of branches are generated and organized." [GOC:dph] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001763 ! morphogenesis of a branching structure relationship: regulates GO:0001763 ! morphogenesis of a branching structure created_by: dph creation_date: 2009-06-05T12:41:44Z [Term] id: GO:0060706 name: cell differentiation involved in embryonic placenta development namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of the embryonic placenta." [GOC:dph] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: part_of GO:0001892 ! embryonic placenta development relationship: part_of GO:0001892 ! embryonic placenta development created_by: dph creation_date: 2009-06-09T10:26:42Z [Term] id: GO:0060711 name: labyrinthine layer development namespace: biological_process def: "The process in which the labyrinthine layer of the placenta progresses, from its formation to its mature state." [GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003946 ! placenta labyrinth relationship: part_of GO:0001892 ! embryonic placenta development relationship: results_in_development_of UBERON:0003946 ! placenta labyrinth created_by: dph creation_date: 2009-06-09T03:27:43Z [Term] id: GO:0060713 name: labyrinthine layer morphogenesis namespace: biological_process def: "The process in which the labyrinthine layer of the placenta is generated and organized." [GOC:dph] is_a: GO:0048598 ! embryonic morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003946 ! placenta labyrinth relationship: part_of GO:0060669 ! embryonic placenta morphogenesis relationship: part_of GO:0060711 ! labyrinthine layer development relationship: results_in_morphogenesis_of UBERON:0003946 ! placenta labyrinth created_by: dph creation_date: 2009-06-10T08:10:19Z [Term] id: GO:0060714 name: labyrinthine layer formation namespace: biological_process def: "The developmental process pertaining to the initial formation of the labyrinthine layer of the placenta." [GOC:dph] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0003946 ! placenta labyrinth relationship: part_of GO:0060713 ! labyrinthine layer morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0003946 ! placenta labyrinth created_by: dph creation_date: 2009-06-10T08:13:14Z [Term] id: GO:0060716 name: labyrinthine layer blood vessel development namespace: biological_process def: "The process whose specific outcome is the progression of a blood vessel of the labyrinthine layer of the placenta over time, from its formation to the mature structure. The embryonic vessels grow through the layer to come in close contact with the maternal blood supply." [GOC:dph] is_a: GO:0048568 ! embryonic organ development is_a: GO:0060674 ! placenta blood vessel development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004183 ! placental labyrinth blood vessel relationship: part_of GO:0060711 ! labyrinthine layer development relationship: results_in_development_of UBERON:0004183 ! placental labyrinth blood vessel created_by: dph creation_date: 2009-06-11T09:04:38Z [Term] id: GO:0060717 name: chorion development namespace: biological_process def: "The biological process whose specific outcome is the progression of a chorion from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The chorion is an extraembryonic membrane." [GOC:dph] is_a: GO:1903867 ! extraembryonic membrane development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003124 ! chorion membrane relationship: results_in_development_of UBERON:0003124 ! chorion membrane created_by: dph creation_date: 2009-06-11T02:37:50Z [Term] id: GO:0060718 name: chorionic trophoblast cell differentiation namespace: biological_process def: "The process in which relatively unspecialized cells of the ectoplacental cone acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer." [CL:0011101, GOC:dph, PMID:16983341] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0011101 ! chorionic trophoblast cell relationship: part_of GO:0060717 ! chorion development relationship: results_in_acquisition_of_features_of CL:0011101 ! chorionic trophoblast cell created_by: dph creation_date: 2009-06-11T02:48:27Z [Term] id: GO:0060719 name: chorionic trophoblast cell development namespace: biological_process def: "The process whose specific outcome is the progression of the chorionic trophoblast over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." [CL:0011101, GOC:16983341, GOC:dph] is_a: GO:0048468 ! cell development intersection_of: GO:0048468 ! cell development intersection_of: results_in_development_of CL:0011101 ! chorionic trophoblast cell relationship: part_of GO:0060718 ! chorionic trophoblast cell differentiation relationship: results_in_development_of CL:0011101 ! chorionic trophoblast cell created_by: dph creation_date: 2009-06-11T02:58:45Z [Term] id: GO:0060722 name: cell proliferation involved in embryonic placenta development namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of the population in the embryonic placenta." [GOC:dph] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: part_of GO:0001892 ! embryonic placenta development relationship: part_of GO:0001892 ! embryonic placenta development created_by: dph creation_date: 2009-06-12T12:46:04Z [Term] id: GO:0060723 name: regulation of cell proliferation involved in embryonic placenta development namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of cell proliferation involved in embryonic placenta development." [GOC:dph] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060722 ! cell proliferation involved in embryonic placenta development relationship: regulates GO:0060722 ! cell proliferation involved in embryonic placenta development created_by: dph creation_date: 2009-06-12T12:50:23Z [Term] id: GO:0060788 name: ectodermal placode formation namespace: biological_process def: "The developmental process in which an ectodermal placode forms. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0005085 ! ectodermal placode relationship: part_of GO:0071697 ! ectodermal placode morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0005085 ! ectodermal placode created_by: dph creation_date: 2009-08-04T12:15:57Z [Term] id: GO:0060795 name: cell fate commitment involved in formation of primary germ layer namespace: biological_process def: "The commitment of cells to specific cell fates of the endoderm, ectoderm, or mesoderm as a part of gastrulation." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0045165 ! cell fate commitment intersection_of: GO:0045165 ! cell fate commitment intersection_of: part_of GO:0001704 ! formation of primary germ layer relationship: part_of GO:0001704 ! formation of primary germ layer created_by: dph creation_date: 2009-08-04T03:11:22Z [Term] id: GO:0060800 name: regulation of cell differentiation involved in embryonic placenta development namespace: biological_process def: "Any process that modulates the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0045595 ! regulation of cell differentiation is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060706 ! cell differentiation involved in embryonic placenta development relationship: regulates GO:0060706 ! cell differentiation involved in embryonic placenta development created_by: dph creation_date: 2009-08-06T01:20:25Z [Term] id: GO:0060806 name: negative regulation of cell differentiation involved in embryonic placenta development namespace: biological_process def: "Any process that decreases the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0060800 ! regulation of cell differentiation involved in embryonic placenta development is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060706 ! cell differentiation involved in embryonic placenta development relationship: negatively_regulates GO:0060706 ! cell differentiation involved in embryonic placenta development created_by: dph creation_date: 2009-08-06T02:02:18Z [Term] id: GO:0060815 name: regulation of translation involved in anterior/posterior axis specification namespace: biological_process def: "Any process that modulates the frequency, rate or extent of translation of mRNAs that contribute to the specification of the anterior/posterior axis." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0006417 ! regulation of translation intersection_of: GO:0006417 ! regulation of translation intersection_of: part_of GO:0009948 ! anterior/posterior axis specification relationship: part_of GO:0009948 ! anterior/posterior axis specification created_by: dph creation_date: 2009-08-07T10:02:31Z [Term] id: GO:0060837 name: blood vessel endothelial cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell, a thin flattened cell that lines the inside surfaces of blood vessels." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0045446 ! endothelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000071 ! blood vessel endothelial cell relationship: part_of GO:0001568 ! blood vessel development relationship: results_in_acquisition_of_features_of CL:0000071 ! blood vessel endothelial cell created_by: dph creation_date: 2009-08-11T03:47:36Z [Term] id: GO:0060840 name: artery development namespace: biological_process def: "The progression of the artery over time, from its initial formation to the mature structure. An artery is a blood vessel that carries blood away from the heart to a capillary bed." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0001568 ! blood vessel development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001637 ! artery relationship: results_in_development_of UBERON:0001637 ! artery created_by: dph creation_date: 2009-08-12T10:10:51Z [Term] id: GO:0060841 name: venous blood vessel development namespace: biological_process def: "The progression of the venous blood vessel over time from its initial formation to the mature structure. Venous blood vessels carry blood back to the heart after the capillary bed." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0001568 ! blood vessel development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001638 ! vein relationship: results_in_development_of UBERON:0001638 ! vein created_by: dph creation_date: 2009-08-12T10:14:07Z [Term] id: GO:0060842 name: arterial endothelial cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized endothelial cell acquires specialized features of an arterial endothelial cell, a thin flattened cell that lines the inside surfaces of arteries." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0060837 ! blood vessel endothelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:1000413 ! endothelial cell of artery relationship: results_in_acquisition_of_features_of CL:1000413 ! endothelial cell of artery created_by: dph creation_date: 2009-08-12T10:41:34Z [Term] id: GO:0060843 name: venous endothelial cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized endothelial cell acquires specialized features of a venous endothelial cell, a thin flattened cell that lines the inside surfaces of veins." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0060837 ! blood vessel endothelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0002543 ! vein endothelial cell relationship: results_in_acquisition_of_features_of CL:0002543 ! vein endothelial cell created_by: dph creation_date: 2009-08-12T10:43:40Z [Term] id: GO:0060896 name: neural plate pattern specification namespace: biological_process def: "The developmental process that results in the creation of defined areas or spaces within the neural plate to which cells respond and eventually are instructed to differentiate." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0007389 ! pattern specification process created_by: dph creation_date: 2009-08-13T02:06:27Z [Term] id: GO:0060897 name: neural plate regionalization namespace: biological_process def: "The pattern specification process that results in the subdivision of an axis or axes of the neural plate in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0003002 ! regionalization is_a: GO:0060896 ! neural plate pattern specification created_by: dph creation_date: 2009-08-13T02:09:04Z [Term] id: GO:0060900 name: embryonic camera-type eye formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a camera-type eye from unspecified neurectoderm. This process begins with the differentiation of cells that form the optic field and ends when the optic cup has attained its shape." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis relationship: part_of GO:0048596 ! embryonic camera-type eye morphogenesis created_by: dph creation_date: 2009-08-13T02:26:54Z [Term] id: GO:0060914 name: heart formation namespace: biological_process def: "The developmental process pertaining to the initial formation of the heart from unspecified parts. This process begins with the specific processes that contribute to the appearance of the heart field and the arrival of cardiac neural crest to the heart region. The process ends when the structural rudiment is recognizable." [GOC:mtg_heart] synonym: "cardiogenesis" RELATED [GOC:mtg_heart] is_a: GO:0048645 ! animal organ formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0000948 ! heart relationship: part_of GO:0003007 ! heart morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0000948 ! heart created_by: dph creation_date: 2009-09-17T09:02:13Z [Term] id: GO:0060915 name: mesenchymal cell differentiation involved in lung development namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the lung. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types." [GOC:dph] is_a: GO:0048762 ! mesenchymal cell differentiation intersection_of: GO:0048762 ! mesenchymal cell differentiation intersection_of: part_of GO:0030324 ! lung development relationship: part_of GO:0030324 ! lung development created_by: dph creation_date: 2009-09-18T11:45:33Z [Term] id: GO:0060916 name: mesenchymal cell proliferation involved in lung development namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population that contributes to the progression of the lung over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." [GOC:dph] is_a: GO:0010463 ! mesenchymal cell proliferation intersection_of: GO:0010463 ! mesenchymal cell proliferation intersection_of: part_of GO:0030324 ! lung development relationship: part_of GO:0030324 ! lung development created_by: dph creation_date: 2009-09-18T11:50:17Z [Term] id: GO:0060920 name: cardiac pacemaker cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a pacemaker cell. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions." [GOC:mtg_cardiac_conduct_nov11, GOC:mtg_heart] synonym: "pacemaker cell differentiation" BROAD [] is_a: GO:0055007 ! cardiac muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0002072 ! nodal myocyte relationship: results_in_acquisition_of_features_of CL:0002072 ! nodal myocyte created_by: dph creation_date: 2009-09-29T11:01:31Z [Term] id: GO:0060921 name: sinoatrial node cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a sinoatrial (SA) node cell. SA node cells are pacemaker cells that are found in the sinoatrial node." [GOC:mtg_heart] synonym: "SA node cell differentiation" EXACT [GOC:mtg_heart] synonym: "SAN cell differentiation" EXACT [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "sinus node cell differentiation" NARROW [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] is_a: GO:0060920 ! cardiac pacemaker cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:1000409 ! myocyte of sinoatrial node relationship: part_of GO:0003163 ! sinoatrial node development relationship: results_in_acquisition_of_features_of CL:1000409 ! myocyte of sinoatrial node created_by: dph creation_date: 2009-09-29T11:03:30Z [Term] id: GO:0060922 name: atrioventricular node cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of an atrioventricular (AV) node cell. AV node cells are pacemaker cells that are found in the atrioventricular node." [GOC:mtg_heart] synonym: "AV node cell differentiation" RELATED [GOC:mtg_heart] is_a: GO:0003292 ! cardiac septum cell differentiation is_a: GO:0060920 ! cardiac pacemaker cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:1000410 ! myocyte of atrioventricular node relationship: part_of GO:0003162 ! atrioventricular node development relationship: results_in_acquisition_of_features_of CL:1000410 ! myocyte of atrioventricular node created_by: dph creation_date: 2009-09-29T11:07:06Z [Term] id: GO:0060926 name: cardiac pacemaker cell development namespace: biological_process def: "The process whose specific outcome is the progression of a pacemaker cell over time, from its formation to the mature state. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions." [GOC:mtg_cardiac_conduct_nov11, GOC:mtg_heart] synonym: "pacemaker cell development" BROAD [] is_a: GO:0055013 ! cardiac muscle cell development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of CL:0002072 ! nodal myocyte relationship: part_of GO:0060920 ! cardiac pacemaker cell differentiation relationship: results_in_development_of CL:0002072 ! nodal myocyte created_by: dph creation_date: 2009-09-29T11:51:55Z [Term] id: GO:0060928 name: atrioventricular node cell development namespace: biological_process def: "The process whose specific outcome is the progression of an atrioventricular (AV) node cell over time, from its formation to the mature state." [GOC:mtg_heart] synonym: "AV node cell development" EXACT [GOC:mtg_heart] is_a: GO:0060926 ! cardiac pacemaker cell development intersection_of: GO:0048468 ! cell development intersection_of: results_in_development_of CL:1000410 ! myocyte of atrioventricular node relationship: part_of GO:0060922 ! atrioventricular node cell differentiation relationship: results_in_development_of CL:1000410 ! myocyte of atrioventricular node created_by: dph creation_date: 2009-09-29T11:59:26Z [Term] id: GO:0060931 name: sinoatrial node cell development namespace: biological_process def: "The process whose specific outcome is the progression of a sinoatrial (SA) node cell over time, from its formation to the mature state. SA node cells are pacemaker cells that are found in the sinoatrial node." [GOC:mtg_heart] synonym: "SA node cell development" EXACT [GOC:mtg_heart] synonym: "SAN cell development" EXACT [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "sinus node cell development" NARROW [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] is_a: GO:0060926 ! cardiac pacemaker cell development intersection_of: GO:0048468 ! cell development intersection_of: results_in_development_of CL:1000409 ! myocyte of sinoatrial node relationship: part_of GO:0060921 ! sinoatrial node cell differentiation relationship: results_in_development_of CL:1000409 ! myocyte of sinoatrial node created_by: dph creation_date: 2009-09-29T12:05:47Z [Term] id: GO:0060932 name: His-Purkinje system cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the His-Purkinje system. These cells form the fibers regulate cardiac muscle contraction in the ventricles." [GOC:mtg_heart] is_a: GO:0055007 ! cardiac muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0010007 ! His-Purkinje system cell relationship: part_of GO:0003164 ! His-Purkinje system development relationship: results_in_acquisition_of_features_of CL:0010007 ! His-Purkinje system cell created_by: dph creation_date: 2009-09-29T01:10:32Z [Term] id: GO:0060933 name: His-Purkinje system cell development namespace: biological_process def: "The process whose specific outcome is the progression of a His-Purkinje cell over time, from its formation to the mature state. These cells form the fibers that regulate cardiac muscle contraction in the ventricles." [GOC:mtg_heart] is_a: GO:0055006 ! cardiac cell development intersection_of: GO:0048468 ! cell development intersection_of: results_in_development_of CL:0010007 ! His-Purkinje system cell relationship: part_of GO:0060932 ! His-Purkinje system cell differentiation relationship: results_in_development_of CL:0010007 ! His-Purkinje system cell created_by: dph creation_date: 2009-09-29T01:15:02Z [Term] id: GO:0060935 name: cardiac fibroblast cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules." [GOC:mtg_heart] is_a: GO:0035051 ! cardiocyte differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0002548 ! fibroblast of cardiac tissue relationship: results_in_acquisition_of_features_of CL:0002548 ! fibroblast of cardiac tissue created_by: dph creation_date: 2009-09-29T01:20:04Z [Term] id: GO:0060936 name: cardiac fibroblast cell development namespace: biological_process def: "The process whose specific outcome is the progression of a cardiac fibroblast over time, from its formation to the mature state. A cardiac fibroblast is a connective tissue cell of the heart which secretes an extracellular matrix rich in collagen and other macromolecules." [GOC:mtg_heart] is_a: GO:0055006 ! cardiac cell development intersection_of: GO:0048468 ! cell development intersection_of: results_in_development_of CL:0002548 ! fibroblast of cardiac tissue relationship: part_of GO:0060935 ! cardiac fibroblast cell differentiation relationship: results_in_development_of CL:0002548 ! fibroblast of cardiac tissue created_by: dph creation_date: 2009-09-29T01:23:03Z [Term] id: GO:0060945 name: cardiac neuron differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a neuron of the heart." [GOC:mtg_heart] synonym: "heart neuron differentiation" EXACT [GOC:mtg_heart] is_a: GO:0030182 ! neuron differentiation is_a: GO:0035051 ! cardiocyte differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0010022 ! cardiac neuron relationship: part_of GO:0048483 ! autonomic nervous system development relationship: results_in_acquisition_of_features_of CL:0010022 ! cardiac neuron created_by: dph creation_date: 2009-09-29T02:45:33Z [Term] id: GO:0060946 name: cardiac blood vessel endothelial cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell of the heart. Blood vessel endothelial cells are thin flattened cells that line the inside surfaces of blood vessels." [GOC:mtg_heart] is_a: GO:0003348 ! cardiac endothelial cell differentiation is_a: GO:0060837 ! blood vessel endothelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0010006 ! cardiac blood vessel endothelial cell relationship: results_in_acquisition_of_features_of CL:0010006 ! cardiac blood vessel endothelial cell created_by: dph creation_date: 2009-09-29T02:48:55Z [Term] id: GO:0060950 name: cardiac glial cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized features of a glial cell of the heart." [GOC:mtg_heart] is_a: GO:0010001 ! glial cell differentiation is_a: GO:0035051 ! cardiocyte differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0010020 ! cardiac glial cell relationship: results_in_acquisition_of_features_of CL:0010020 ! cardiac glial cell created_by: dph creation_date: 2009-09-29T03:06:37Z [Term] id: GO:0060952 name: cardiac glial cell development namespace: biological_process def: "The process aimed at the progression of a cardiac glial cell over time, from its formation to the fully functional mature cell." [GOC:mtg_heart] is_a: GO:0021782 ! glial cell development is_a: GO:0055006 ! cardiac cell development intersection_of: GO:0048468 ! cell development intersection_of: results_in_development_of CL:0010020 ! cardiac glial cell relationship: part_of GO:0060950 ! cardiac glial cell differentiation relationship: results_in_development_of CL:0010020 ! cardiac glial cell created_by: dph creation_date: 2009-09-29T03:09:24Z [Term] id: GO:0060956 name: endocardial cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart. The endocardium is the innermost layer of tissue of the heart, and lines the heart chambers." [GOC:mtg_heart] is_a: GO:0003348 ! cardiac endothelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0002350 ! endocardial cell relationship: part_of GO:0003157 ! endocardium development relationship: results_in_acquisition_of_features_of CL:0002350 ! endocardial cell created_by: dph creation_date: 2009-09-29T03:20:39Z [Term] id: GO:0060958 name: endocardial cell development namespace: biological_process def: "The progression of an endocardial cell over time, from its formation to the mature cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart." [GOC:mtg_heart] is_a: GO:0001885 ! endothelial cell development is_a: GO:0055006 ! cardiac cell development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of CL:0002350 ! endocardial cell relationship: part_of GO:0060956 ! endocardial cell differentiation relationship: results_in_development_of CL:0002350 ! endocardial cell created_by: dph creation_date: 2009-09-29T03:26:59Z [Term] id: GO:0060959 name: cardiac neuron development namespace: biological_process def: "The process whose specific outcome is the progression of a cardiac neuron over time, from its formation to the mature state." [GOC:mtg_heart] synonym: "heart neuron development" EXACT [GOC:mtg_heart] is_a: GO:0048666 ! neuron development is_a: GO:0055006 ! cardiac cell development intersection_of: GO:0048468 ! cell development intersection_of: results_in_development_of CL:0010022 ! cardiac neuron relationship: part_of GO:0060945 ! cardiac neuron differentiation relationship: results_in_development_of CL:0010022 ! cardiac neuron created_by: dph creation_date: 2009-09-30T10:14:56Z [Term] id: GO:0060973 name: cell migration involved in heart development namespace: biological_process def: "The orderly movement of a cell from one site to another that will contribute to the progression of the heart over time, from its initial formation, to the mature organ." [GOC:mtg_heart] is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: part_of GO:0007507 ! heart development relationship: part_of GO:0007507 ! heart development created_by: dph creation_date: 2009-10-06T10:53:49Z [Term] id: GO:0060974 name: cell migration involved in heart formation namespace: biological_process def: "The orderly movement of a cell from one site to another that contribute to the formation of the heart. The initial heart structure is made up of mesoderm-derived heart progenitor cells and neural crest-derived cells." [GOC:mtg_heart] is_a: GO:0060973 ! cell migration involved in heart development intersection_of: GO:0016477 ! cell migration intersection_of: part_of GO:0060914 ! heart formation relationship: part_of GO:0060914 ! heart formation created_by: dph creation_date: 2009-10-06T10:56:33Z [Term] id: GO:0060976 name: coronary vasculature development namespace: biological_process def: "The process whose specific outcome is the progression of the blood vessels of the heart over time, from its formation to the mature structure." [GOC:mtg_heart] synonym: "cardiac blood vessel development" EXACT [GOC:mtg_heart] synonym: "cardiac vasculature development" EXACT [GOC:mtg_heart] synonym: "coronary blood vessel development" EXACT [GOC:mtg_heart] synonym: "heart blood vessel development" EXACT [GOC:mtg_heart] synonym: "heart vasculature development" EXACT [GOC:mtg_heart] is_a: GO:0001568 ! blood vessel development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003498 ! heart blood vessel relationship: part_of GO:0007507 ! heart development relationship: results_in_development_of UBERON:0003498 ! heart blood vessel created_by: dph creation_date: 2009-10-06T12:15:23Z [Term] id: GO:0060977 name: coronary vasculature morphogenesis namespace: biological_process def: "The process in which the anatomical structures of blood vessels of the heart are generated and organized. The blood vessel is the vasculature carrying blood." [GOC:mtg_heart] synonym: "cardiac blood vessel morphogenesis" EXACT [GOC:mtg_heart] synonym: "cardiac vasculature morphogenesis" EXACT [GOC:mtg_heart] synonym: "coronary blood vessel morphogenesis" EXACT [GOC:mtg_heart] synonym: "heart blood vessel morphogenesis" EXACT [GOC:mtg_heart] synonym: "heart vasculature morphogenesis" EXACT [GOC:mtg_heart] is_a: GO:0048514 ! blood vessel morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003498 ! heart blood vessel relationship: part_of GO:0060976 ! coronary vasculature development relationship: results_in_morphogenesis_of UBERON:0003498 ! heart blood vessel created_by: dph creation_date: 2009-10-06T12:28:23Z [Term] id: GO:0060978 name: angiogenesis involved in coronary vascular morphogenesis namespace: biological_process def: "Blood vessel formation in the heart when new vessels emerge from the proliferation of pre-existing blood vessels." [GOC:mtg_heart] synonym: "angiogenesis involved in cardiac vascular morphogenesis" EXACT [GOC:mtg_heart] synonym: "angiogenesis involved in heart vascular morphogenesis" EXACT [GOC:mtg_heart] synonym: "coronary blood vessel angiogenesis" EXACT [GOC:mtg_heart] synonym: "coronary vasculature angiogenesis" EXACT [GOC:mtg_heart] is_a: GO:0001525 ! angiogenesis intersection_of: GO:0001525 ! angiogenesis intersection_of: part_of GO:0060976 ! coronary vasculature development relationship: part_of GO:0060977 ! coronary vasculature morphogenesis created_by: dph creation_date: 2009-10-06T02:02:12Z [Term] id: GO:0060979 name: vasculogenesis involved in coronary vascular morphogenesis namespace: biological_process def: "The differentiation of endothelial cells from progenitor cells that contributes to blood vessel development in the heart, and the de novo formation of blood vessels and tubes." [GOC:mtg_heart] synonym: "coronary vasculogenesis" EXACT [GOC:mtg_heart] synonym: "vasculogenesis involved in coronary blood vessel morphogenesis" EXACT [GOC:mtg_heart] is_a: GO:0001570 ! vasculogenesis intersection_of: GO:0001570 ! vasculogenesis intersection_of: part_of GO:0060977 ! coronary vasculature morphogenesis relationship: part_of GO:0060977 ! coronary vasculature morphogenesis created_by: dph creation_date: 2009-10-06T02:19:42Z [Term] id: GO:0060980 name: cell migration involved in coronary vasculogenesis namespace: biological_process def: "The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form the blood vessels of the heart." [GOC:mtg_heart] is_a: GO:0035441 ! cell migration involved in vasculogenesis is_a: GO:0060973 ! cell migration involved in heart development intersection_of: GO:0016477 ! cell migration intersection_of: part_of GO:0060979 ! vasculogenesis involved in coronary vascular morphogenesis relationship: part_of GO:0060979 ! vasculogenesis involved in coronary vascular morphogenesis created_by: dph creation_date: 2009-10-06T02:33:06Z [Term] id: GO:0060981 name: cell migration involved in coronary angiogenesis namespace: biological_process def: "The orderly movement of a cell from one site to another that will contribute to the formation of new blood vessels in the heart from pre-existing blood vessels." [GOC:mtg_heart] is_a: GO:0060973 ! cell migration involved in heart development intersection_of: GO:0016477 ! cell migration intersection_of: part_of GO:0060978 ! angiogenesis involved in coronary vascular morphogenesis relationship: part_of GO:0060978 ! angiogenesis involved in coronary vascular morphogenesis created_by: dph creation_date: 2009-10-06T02:49:12Z [Term] id: GO:0060986 name: endocrine hormone secretion namespace: biological_process def: "The regulated release of a hormone into the circulatory system." [GOC:dph] is_a: GO:0046879 ! hormone secretion relationship: part_of GO:0050886 ! endocrine process created_by: dph creation_date: 2010-01-11T09:03:48Z [Term] id: GO:0060993 name: kidney morphogenesis namespace: biological_process def: "Morphogenesis of a kidney. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:dph, GOC:mtg_kidney_jan10] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002113 ! kidney relationship: part_of GO:0001822 ! kidney development relationship: results_in_morphogenesis_of UBERON:0002113 ! kidney created_by: dph creation_date: 2010-01-19T08:16:55Z [Term] id: GO:0060995 name: cell-cell signaling involved in kidney development namespace: biological_process def: "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the kidney over time, from its formation to the mature organ." [GOC:dph, GOC:mtg_kidney_jan10] synonym: "cell-cell signalling involved in kidney development" EXACT [GOC:mah] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: part_of GO:0001822 ! kidney development relationship: part_of GO:0001822 ! kidney development created_by: dph creation_date: 2010-01-19T08:33:40Z [Term] id: GO:0061004 name: pattern specification involved in kidney development namespace: biological_process def: "Any developmental process that results in the creation of defined areas or spaces within the kidney to which cells respond and eventually are instructed to differentiate." [GOC:dph, GOC:mtg_kidney_jan10] synonym: "kidney pattern formation" RELATED [GOC:mtg_kidney_jan10] synonym: "kidney pattern specification" EXACT [GOC:mtg_kidney_jan10] synonym: "pattern formation involved in kidney development" RELATED [GOC:mtg_kidney_jan10] is_a: GO:0007389 ! pattern specification process intersection_of: GO:0007389 ! pattern specification process intersection_of: part_of GO:0001822 ! kidney development relationship: part_of GO:0001822 ! kidney development relationship: part_of GO:0072048 ! renal system pattern specification created_by: dph creation_date: 2010-01-21T09:05:54Z [Term] id: GO:0061005 name: cell differentiation involved in kidney development namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the kidney as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: part_of GO:0001822 ! kidney development relationship: part_of GO:0001822 ! kidney development created_by: dph creation_date: 2010-01-21T09:13:55Z [Term] id: GO:0061006 name: regulation of cell proliferation involved in kidney morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell proliferation that contributes to the shaping of the kidney." [GOC:dph, GOC:mtg_kidney_jan10] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0042127 ! regulation of cell population proliferation intersection_of: part_of GO:0060993 ! kidney morphogenesis relationship: part_of GO:0060993 ! kidney morphogenesis created_by: dph creation_date: 2010-01-21T11:25:23Z [Term] id: GO:0061007 name: hepaticobiliary system process namespace: biological_process def: "An system process carried out by any of the organs or tissues of the hepaticobiliary system. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins." [GOC:dph] subset: goslim_generic synonym: "hepatobiliary system process" EXACT [GOC:dph] is_a: GO:0003008 ! system process created_by: dph creation_date: 2010-01-22T09:09:10Z [Term] id: GO:0061008 name: hepaticobiliary system development namespace: biological_process def: "The progression of the hepaticobiliary system over time, from its formation to the mature structure. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins." [GOC:dph] synonym: "hepatobiliary system development" EXACT [GOC:dph] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002423 ! hepatobiliary system relationship: results_in_development_of UBERON:0002423 ! hepatobiliary system created_by: dph creation_date: 2010-01-22T09:11:59Z [Term] id: GO:0061009 name: common bile duct development namespace: biological_process def: "The progression of the common bile duct over time, from its formation to the mature structure. The common bile duct is formed from the joining of the common hepatic duct running from the liver, and the cystic duct running from the gallbladder. The common bile duct transports bile from the liver and gallbladder to the intestine." [PMID:20614624] synonym: "bile duct development" EXACT [GOC:dph] synonym: "CBD development" EXACT [PMID:20614624] synonym: "EHBD development" BROAD [PMID:20614624] synonym: "extrahepatic bile duct development" BROAD [PMID:20614624] is_a: GO:0035295 ! tube development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002394 ! bile duct relationship: part_of GO:0061008 ! hepaticobiliary system development relationship: results_in_development_of UBERON:0002394 ! bile duct created_by: dph creation_date: 2010-01-22T09:17:13Z [Term] id: GO:0061010 name: gallbladder development namespace: biological_process def: "The progression of the gallbladder over time, from its initial formation to the mature structure. The gallbladder is a cavitated organ that stores bile." [GOC:dph] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002110 ! gallbladder relationship: part_of GO:0061008 ! hepaticobiliary system development relationship: results_in_development_of UBERON:0002110 ! gallbladder created_by: dph creation_date: 2010-01-22T09:38:44Z [Term] id: GO:0061011 name: hepatic duct development namespace: biological_process def: "The progression of the hepatic duct over time, from its formation to the mature structure. The hepatic duct is the duct that leads from the liver to the common bile duct." [GOC:dph, PMID:20614624] is_a: GO:0061009 ! common bile duct development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001175 ! common hepatic duct relationship: results_in_development_of UBERON:0001175 ! common hepatic duct created_by: dph creation_date: 2010-01-22T09:44:39Z [Term] id: GO:0061017 name: hepatoblast differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a hepatoblast. A hepatoblast is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into hepatocytes and cholangiocytes." [GOC:dph, PMID:15226394] is_a: GO:0030855 ! epithelial cell differentiation is_a: GO:0048863 ! stem cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:1000488 ! cholangiocyte relationship: part_of GO:0001889 ! liver development relationship: results_in_acquisition_of_features_of CL:1000488 ! cholangiocyte created_by: dph creation_date: 2010-02-02T09:08:03Z [Term] id: GO:0061024 name: membrane organization namespace: biological_process alt_id: GO:0016044 alt_id: GO:0044802 def: "A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins." [GOC:dph, GOC:tb] subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_pir subset: goslim_pombe subset: goslim_prokaryote synonym: "cellular membrane organisation" EXACT [] synonym: "cellular membrane organization" EXACT [] synonym: "membrane organisation" EXACT [GOC:mah] synonym: "membrane organization and biogenesis" RELATED [GOC:mah] synonym: "single-organism membrane organization" RELATED [] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0016020 ! membrane relationship: results_in_organization_of GO:0016020 ! membrane created_by: jl creation_date: 2010-02-08T02:43:11Z [Term] id: GO:0061025 name: membrane fusion namespace: biological_process alt_id: GO:0006944 alt_id: GO:0044801 def: "The membrane organization process that joins two lipid bilayers to form a single membrane." [GOC:dph, GOC:tb] subset: goslim_yeast synonym: "cellular membrane fusion" EXACT [] synonym: "single-organism membrane fusion" RELATED [] xref: Wikipedia:Lipid_bilayer_fusion is_a: GO:0061024 ! membrane organization intersection_of: GO:0061024 ! membrane organization intersection_of: results_in_fusion_of GO:0016020 ! membrane relationship: results_in_fusion_of GO:0016020 ! membrane created_by: jl creation_date: 2010-02-08T02:48:06Z [Term] id: GO:0061027 name: umbilical cord development namespace: biological_process def: "The process whose specific outcome is the development of the umbilical cord, from its formation to the mature structure. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta." [GOC:BHF, GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002331 ! umbilical cord relationship: results_in_development_of UBERON:0002331 ! umbilical cord created_by: dph creation_date: 2010-02-09T09:09:22Z [Term] id: GO:0061032 name: visceral serous pericardium development namespace: biological_process def: "The progression of the visceral serous pericardium from its formation to the mature structure. The visceral serous pericardium is the inner layer of the pericardium." [GOC:dph, GOC:yaf] synonym: "epicardium development" EXACT [GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002425 ! visceral serous pericardium relationship: part_of GO:0060039 ! pericardium development relationship: results_in_development_of UBERON:0002425 ! visceral serous pericardium created_by: dph creation_date: 2010-02-09T09:52:49Z [Term] id: GO:0061035 name: regulation of cartilage development namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." [GOC:dph] is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0051216 ! cartilage development relationship: regulates GO:0051216 ! cartilage development created_by: dph creation_date: 2010-02-09T03:41:35Z [Term] id: GO:0061036 name: positive regulation of cartilage development namespace: biological_process def: "Any process that increases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." [GOC:dph] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:0061035 ! regulation of cartilage development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0051216 ! cartilage development relationship: positively_regulates GO:0051216 ! cartilage development created_by: dph creation_date: 2010-02-09T03:41:35Z [Term] id: GO:0061037 name: negative regulation of cartilage development namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." [GOC:dph] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:0061035 ! regulation of cartilage development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0051216 ! cartilage development relationship: negatively_regulates GO:0051216 ! cartilage development created_by: dph creation_date: 2010-02-09T03:41:35Z [Term] id: GO:0061038 name: uterus morphogenesis namespace: biological_process def: "The process in which anatomical structures of the uterus are generated and organized." [GOC:BHF, GOC:dph] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000995 ! uterus relationship: part_of GO:0060065 ! uterus development relationship: results_in_morphogenesis_of UBERON:0000995 ! uterus created_by: dph creation_date: 2010-02-22T11:12:35Z [Term] id: GO:0061040 name: female gonad morphogenesis namespace: biological_process def: "The process in which a female gonad is generated and organized." [GOC:BHF, GOC:dph] synonym: "ovary morphogenesis" RELATED [GOC:dph, GOC:tb] is_a: GO:0035262 ! gonad morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000992 ! ovary relationship: part_of GO:0008585 ! female gonad development relationship: results_in_morphogenesis_of UBERON:0000992 ! ovary created_by: dph creation_date: 2010-02-22T11:29:28Z [Term] id: GO:0061046 name: regulation of branching involved in lung morphogenesis namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units." [GOC:dph, GOC:yaf] is_a: GO:0060688 ! regulation of morphogenesis of a branching structure is_a: GO:1905330 ! regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060441 ! epithelial tube branching involved in lung morphogenesis relationship: regulates GO:0060441 ! epithelial tube branching involved in lung morphogenesis created_by: dph creation_date: 2010-02-25T10:41:38Z [Term] id: GO:0061047 name: positive regulation of branching involved in lung morphogenesis namespace: biological_process def: "Any process that increases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units." [GOC:dph, GOC:yaf] is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:0061046 ! regulation of branching involved in lung morphogenesis is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060441 ! epithelial tube branching involved in lung morphogenesis relationship: positively_regulates GO:0060441 ! epithelial tube branching involved in lung morphogenesis created_by: dph creation_date: 2010-02-25T10:50:01Z [Term] id: GO:0061048 name: negative regulation of branching involved in lung morphogenesis namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units." [GOC:dph, GOC:yaf] is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:0061046 ! regulation of branching involved in lung morphogenesis is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060441 ! epithelial tube branching involved in lung morphogenesis relationship: negatively_regulates GO:0060441 ! epithelial tube branching involved in lung morphogenesis created_by: dph creation_date: 2010-02-25T10:51:31Z [Term] id: GO:0061049 name: cell growth involved in cardiac muscle cell development namespace: biological_process def: "The growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state." [GOC:dph] synonym: "cardiac muscle cell hypertrophy" RELATED [GOC:dph] synonym: "cardiomyocyte growth" RELATED [GOC:dph] synonym: "heart muscle cell growth" RELATED [GOC:dph] is_a: GO:0048588 ! developmental cell growth intersection_of: GO:0016049 ! cell growth intersection_of: part_of GO:0055013 ! cardiac muscle cell development relationship: part_of GO:0003301 ! physiological cardiac muscle hypertrophy relationship: part_of GO:0055013 ! cardiac muscle cell development created_by: dph creation_date: 2010-02-25T12:56:07Z [Term] id: GO:0061050 name: regulation of cell growth involved in cardiac muscle cell development namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state." [GOC:dph] is_a: GO:0001558 ! regulation of cell growth is_a: GO:0055021 ! regulation of cardiac muscle tissue growth intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0061049 ! cell growth involved in cardiac muscle cell development relationship: regulates GO:0061049 ! cell growth involved in cardiac muscle cell development created_by: dph creation_date: 2010-02-25T01:05:16Z [Term] id: GO:0061051 name: positive regulation of cell growth involved in cardiac muscle cell development namespace: biological_process def: "Any process that increases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state." [GOC:dph] is_a: GO:0010613 ! positive regulation of cardiac muscle hypertrophy is_a: GO:0030307 ! positive regulation of cell growth is_a: GO:0051155 ! positive regulation of striated muscle cell differentiation is_a: GO:0055023 ! positive regulation of cardiac muscle tissue growth is_a: GO:0061050 ! regulation of cell growth involved in cardiac muscle cell development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0061049 ! cell growth involved in cardiac muscle cell development relationship: positively_regulates GO:0061049 ! cell growth involved in cardiac muscle cell development created_by: dph creation_date: 2010-02-25T01:08:08Z [Term] id: GO:0061052 name: negative regulation of cell growth involved in cardiac muscle cell development namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state." [GOC:dph] is_a: GO:0010614 ! negative regulation of cardiac muscle hypertrophy is_a: GO:0030308 ! negative regulation of cell growth is_a: GO:0051154 ! negative regulation of striated muscle cell differentiation is_a: GO:0055022 ! negative regulation of cardiac muscle tissue growth is_a: GO:0061050 ! regulation of cell growth involved in cardiac muscle cell development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0061049 ! cell growth involved in cardiac muscle cell development relationship: negatively_regulates GO:0061049 ! cell growth involved in cardiac muscle cell development created_by: dph creation_date: 2010-02-25T01:11:30Z [Term] id: GO:0061053 name: somite development namespace: biological_process def: "The progression of a somite from its initial formation to the mature structure. Somites are mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo." [GOC:dph] is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002329 ! somite relationship: part_of GO:0009790 ! embryo development relationship: results_in_development_of UBERON:0002329 ! somite created_by: dph creation_date: 2010-03-02T12:05:13Z [Term] id: GO:0061054 name: dermatome development namespace: biological_process def: "The progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin." [GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004016 ! dermatome relationship: part_of GO:0061053 ! somite development relationship: results_in_development_of UBERON:0004016 ! dermatome created_by: dph creation_date: 2010-03-02T12:07:37Z [Term] id: GO:0061055 name: myotome development namespace: biological_process def: "The progression of the myotome over time, from its formation to the mature structure. The myotome is the portion of the somite that will give rise to muscle." [GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003082 ! myotome relationship: part_of GO:0061053 ! somite development relationship: results_in_development_of UBERON:0003082 ! myotome created_by: dph creation_date: 2010-03-02T12:11:01Z [Term] id: GO:0061056 name: sclerotome development namespace: biological_process def: "The progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra." [GOC:dph] is_a: GO:0060485 ! mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003089 ! sclerotome relationship: part_of GO:0061053 ! somite development relationship: results_in_development_of UBERON:0003089 ! sclerotome created_by: dph creation_date: 2010-03-02T12:12:40Z [Term] id: GO:0061061 name: muscle structure development namespace: biological_process def: "The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms." [GOC:dph] subset: goslim_drosophila is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005090 ! muscle structure relationship: in_taxon NCBITaxon:6072 {all_only="true"} ! Eumetazoa relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa relationship: results_in_development_of UBERON:0005090 ! muscle structure created_by: dph creation_date: 2010-03-09T08:55:14Z [Term] id: GO:0061062 name: regulation of nematode larval development namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew." [GOC:dph, GOC:kmv] is_a: GO:0048580 ! regulation of post-embryonic development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002119 ! nematode larval development relationship: regulates GO:0002119 ! nematode larval development created_by: dph creation_date: 2010-03-11T12:59:21Z [Term] id: GO:0061063 name: positive regulation of nematode larval development namespace: biological_process def: "Any process that increases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew." [GOC:dph, GOC:kmv] is_a: GO:0048582 ! positive regulation of post-embryonic development is_a: GO:0061062 ! regulation of nematode larval development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002119 ! nematode larval development relationship: positively_regulates GO:0002119 ! nematode larval development created_by: dph creation_date: 2010-03-11T01:03:34Z [Term] id: GO:0061064 name: negative regulation of nematode larval development namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew." [GOC:dph, GOC:kmv] is_a: GO:0048581 ! negative regulation of post-embryonic development is_a: GO:0061062 ! regulation of nematode larval development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002119 ! nematode larval development relationship: negatively_regulates GO:0002119 ! nematode larval development created_by: dph creation_date: 2010-03-11T01:04:39Z [Term] id: GO:0061068 name: urethra development namespace: biological_process def: "The progression of the urethra over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body." [GOC:dph] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000057 ! urethra relationship: part_of GO:0072001 ! renal system development relationship: results_in_development_of UBERON:0000057 ! urethra created_by: dph creation_date: 2010-03-12T08:24:52Z [Term] id: GO:0061069 name: male urethra development namespace: biological_process def: "The progression of the male urethra over time from its initial formation to the mature structure. The male urethra is a renal system organ that carries urine from the bladder through the penis to outside the body." [GOC:dph] is_a: GO:0061068 ! urethra development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001333 ! male urethra relationship: results_in_development_of UBERON:0001333 ! male urethra created_by: dph creation_date: 2010-03-12T08:28:19Z [Term] id: GO:0061070 name: female urethra development namespace: biological_process def: "The progression of the female urethra over time from its initial formation to the mature structure. The female urethra is a renal system organ that carries urine from the bladder to outside the body, exiting above the vaginal opening." [GOC:dph] is_a: GO:0061068 ! urethra development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001334 ! female urethra relationship: results_in_development_of UBERON:0001334 ! female urethra created_by: dph creation_date: 2010-03-12T08:29:43Z [Term] id: GO:0061071 name: urethra epithelium development namespace: biological_process def: "The progression of the urethra epithelium over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body. The epithelium is the tubular, planar layer of cells through which the urine passes." [GOC:dph] is_a: GO:0035295 ! tube development is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002325 ! epithelium of urethra relationship: part_of GO:0061068 ! urethra development relationship: results_in_development_of UBERON:0002325 ! epithelium of urethra created_by: dph creation_date: 2010-03-12T08:36:53Z [Term] id: GO:0061072 name: iris morphogenesis namespace: biological_process def: "The process in which the iris is generated and organized. The iris is an anatomical structure in the eye whose opening forms the pupil. The iris is responsible for controlling the diameter and size of the pupil and the amount of light reaching the retina." [GOC:dph] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001769 ! iris relationship: part_of GO:0048593 ! camera-type eye morphogenesis relationship: results_in_morphogenesis_of UBERON:0001769 ! iris created_by: dph creation_date: 2010-03-16T10:48:42Z [Term] id: GO:0061073 name: ciliary body morphogenesis namespace: biological_process def: "The process in which the ciliary body generated and organized. The ciliary body is the circumferential tissue inside the eye composed of the ciliary muscle and ciliary processes." [GOC:dph] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001775 ! ciliary body relationship: part_of GO:0048593 ! camera-type eye morphogenesis relationship: results_in_morphogenesis_of UBERON:0001775 ! ciliary body created_by: dph creation_date: 2010-03-16T10:55:19Z [Term] id: GO:0061074 name: regulation of neural retina development namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells." [GOC:dph] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003407 ! neural retina development relationship: regulates GO:0003407 ! neural retina development created_by: dph creation_date: 2010-03-16T11:47:05Z [Term] id: GO:0061075 name: positive regulation of neural retina development namespace: biological_process def: "Any process that increases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells." [GOC:dph] is_a: GO:0061074 ! regulation of neural retina development is_a: GO:1902868 ! positive regulation of retina development in camera-type eye intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0003407 ! neural retina development relationship: positively_regulates GO:0003407 ! neural retina development created_by: dph creation_date: 2010-03-16T11:59:48Z [Term] id: GO:0061076 name: negative regulation of neural retina development namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells." [GOC:dph] is_a: GO:0061074 ! regulation of neural retina development is_a: GO:1902867 ! negative regulation of retina development in camera-type eye intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0003407 ! neural retina development relationship: negatively_regulates GO:0003407 ! neural retina development created_by: dph creation_date: 2010-03-16T12:46:11Z [Term] id: GO:0061080 name: right horn of sinus venosus development namespace: biological_process def: "The progression of the right horn of the sinus venosus from its formation to the mature structure." [GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005092 ! right horn of sinus venosus relationship: part_of GO:0003235 ! sinus venosus development relationship: results_in_development_of UBERON:0005092 ! right horn of sinus venosus created_by: dph creation_date: 2010-04-08T02:45:10Z [Term] id: GO:0061100 name: lung neuroendocrine cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the lung epithelium." [GOC:dph, PMID:9126746] is_a: GO:0061101 ! neuroendocrine cell differentiation is_a: GO:0061140 ! lung secretory cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:1000223 ! lung neuroendocrine cell relationship: results_in_acquisition_of_features_of CL:1000223 ! lung neuroendocrine cell created_by: dph creation_date: 2010-04-27T03:28:46Z [Term] id: GO:0061101 name: neuroendocrine cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a neuroendocrine cell. A neuroendocrine cell is a cell that receives input form a neuron which controls the secretion of an endocrine substance." [GOC:dph] is_a: GO:0030182 ! neuron differentiation is_a: GO:0060563 ! neuroepithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000165 ! neuroendocrine cell relationship: results_in_acquisition_of_features_of CL:0000165 ! neuroendocrine cell created_by: dph creation_date: 2010-04-28T09:42:20Z [Term] id: GO:0061102 name: stomach neuroendocrine cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the stomach epithelium." [GOC:dph, PMID:18173746] synonym: "gastric neuroendocrine cell differentiation" RELATED [GOC:dph] is_a: GO:0035883 ! enteroendocrine cell differentiation is_a: GO:0061101 ! neuroendocrine cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:1000222 ! stomach neuroendocrine cell relationship: part_of GO:0062094 ! stomach development relationship: results_in_acquisition_of_features_of CL:1000222 ! stomach neuroendocrine cell created_by: dph creation_date: 2010-04-28T09:47:07Z [Term] id: GO:0061105 name: regulation of stomach neuroendocrine cell differentiation namespace: biological_process def: "Any process that modulates the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach." [GOC:dph] is_a: GO:0030856 ! regulation of epithelial cell differentiation is_a: GO:0045664 ! regulation of neuron differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0061102 ! stomach neuroendocrine cell differentiation relationship: regulates GO:0061102 ! stomach neuroendocrine cell differentiation created_by: dph creation_date: 2010-04-29T12:19:37Z [Term] id: GO:0061106 name: negative regulation of stomach neuroendocrine cell differentiation namespace: biological_process def: "Any process that decreases the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach." [GOC:dph] is_a: GO:0002085 ! inhibition of neuroepithelial cell differentiation is_a: GO:0045665 ! negative regulation of neuron differentiation is_a: GO:0061105 ! regulation of stomach neuroendocrine cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0061102 ! stomach neuroendocrine cell differentiation relationship: negatively_regulates GO:0061102 ! stomach neuroendocrine cell differentiation created_by: dph creation_date: 2010-04-29T12:23:05Z [Term] id: GO:0061107 name: seminal vesicle development namespace: biological_process def: "The progression of the seminal vesicle over time, from its formation to the mature structure. The seminal vesicle is a gland that contributes to the production of semen." [GOC:dph] is_a: GO:0048608 ! reproductive structure development is_a: GO:0048732 ! gland development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000998 ! seminal vesicle relationship: results_in_development_of UBERON:0000998 ! seminal vesicle created_by: dph creation_date: 2010-04-30T10:17:30Z [Term] id: GO:0061108 name: seminal vesicle epithelium development namespace: biological_process def: "The progression of the seminal vesicle epithelium over time, from its formation to the mature structure." [GOC:dph] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0035295 ! tube development is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004805 ! seminal vesicle epithelium relationship: part_of GO:0061107 ! seminal vesicle development relationship: results_in_development_of UBERON:0004805 ! seminal vesicle epithelium created_by: dph creation_date: 2010-04-30T10:19:54Z [Term] id: GO:0061109 name: dense core granule organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a dense core granule. A dense core granule is a secretory organelle found in endocrine cells." [GOC:dph] synonym: "dense core granule organisation" EXACT [GOC:mah] is_a: GO:0033363 ! secretory granule organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0031045 ! dense core granule relationship: results_in_organization_of GO:0031045 ! dense core granule created_by: dph creation_date: 2010-05-01T09:34:37Z [Term] id: GO:0061111 name: epithelial-mesenchymal cell signaling involved in lung development namespace: biological_process def: "Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell and contributes to the progression of the lung over time from its initial formation to the mature organ." [GOC:dph] synonym: "epithelial-mesenchymal cell signalling involved in lung development" EXACT [GOC:mah] is_a: GO:0060495 ! cell-cell signaling involved in lung development is_a: GO:0060684 ! epithelial-mesenchymal cell signaling intersection_of: GO:0060684 ! epithelial-mesenchymal cell signaling intersection_of: part_of GO:0030324 ! lung development created_by: dph creation_date: 2010-05-05T11:14:38Z [Term] id: GO:0061113 name: pancreas morphogenesis namespace: biological_process def: "Morphogenesis of the pancreas. Morphogenesis is the process in which anatomical structures are generated and organized." [GOC:dph] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001264 ! pancreas relationship: part_of GO:0031016 ! pancreas development relationship: results_in_morphogenesis_of UBERON:0001264 ! pancreas created_by: dph creation_date: 2010-05-05T11:55:30Z [Term] id: GO:0061114 name: branching involved in pancreas morphogenesis namespace: biological_process def: "The process in which the branches of the pancreas are generated and organized." [GOC:dph] is_a: GO:0061138 ! morphogenesis of a branching epithelium intersection_of: GO:0061138 ! morphogenesis of a branching epithelium intersection_of: part_of GO:0061113 ! pancreas morphogenesis relationship: part_of GO:0061113 ! pancreas morphogenesis created_by: dph creation_date: 2010-05-05T12:03:04Z [Term] id: GO:0061117 name: negative regulation of heart growth namespace: biological_process def: "Any process that decreases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart." [GOC:dph, GOC:hjd] is_a: GO:0046621 ! negative regulation of organ growth is_a: GO:0060420 ! regulation of heart growth intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060419 ! heart growth relationship: negatively_regulates GO:0060419 ! heart growth created_by: dph creation_date: 2010-05-17T07:31:28Z [Term] id: GO:0061130 name: pancreatic bud formation namespace: biological_process def: "The morphogenetic process in which the foregut region specified to become the pancreas forms a bud." [GOC:dph] is_a: GO:0048645 ! animal organ formation is_a: GO:0061114 ! branching involved in pancreas morphogenesis is_a: GO:0072175 ! epithelial tube formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0003922 ! pancreatic epithelial bud relationship: results_in_formation_of_anatomical_entity UBERON:0003922 ! pancreatic epithelial bud created_by: dph creation_date: 2010-05-17T09:33:40Z [Term] id: GO:0061138 name: morphogenesis of a branching epithelium namespace: biological_process def: "The process in which the anatomical structures of a branched epithelium are generated and organized." [GOC:dph] is_a: GO:0001763 ! morphogenesis of a branching structure is_a: GO:0002009 ! morphogenesis of an epithelium created_by: dph creation_date: 2010-05-25T09:05:34Z [Term] id: GO:0061140 name: lung secretory cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a lung secretory cell. A lung secretory cell is a specialized epithelial cell of the lung that contains large secretory granules in its apical part." [GOC:dph] is_a: GO:0060487 ! lung epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:1000272 ! lung secretory cell relationship: results_in_acquisition_of_features_of CL:1000272 ! lung secretory cell created_by: dph creation_date: 2010-05-25T09:28:53Z [Term] id: GO:0061141 name: lung ciliated cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a lung ciliated cell. A lung ciliated cell is a specialized lung epithelial cell that contains cilia for moving substances released from lung secretory cells." [GOC:cilia, GOC:dph, GOC:krc] is_a: GO:0060487 ! lung epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:1000271 ! lung ciliated cell relationship: results_in_acquisition_of_features_of CL:1000271 ! lung ciliated cell created_by: dph creation_date: 2010-05-25T09:31:14Z [Term] id: GO:0061147 name: endocardial endothelium development namespace: biological_process def: "The progression of the endocardial endothelium over time, from its initial formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers." [GOC:dph] is_a: GO:0003158 ! endothelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005316 ! endocardial endothelium relationship: part_of GO:0003157 ! endocardium development relationship: results_in_development_of UBERON:0005316 ! endocardial endothelium created_by: dph creation_date: 2010-06-03T09:15:31Z [Term] id: GO:0061148 name: extracellular matrix organization involved in endocardium development namespace: biological_process def: "A process which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix of the endocardium. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers." [GOC:dph] synonym: "extracellular matrix organisation involved in endocardium development" EXACT [GOC:mah] is_a: GO:0030198 ! extracellular matrix organization intersection_of: GO:0030198 ! extracellular matrix organization intersection_of: part_of GO:0003157 ! endocardium development relationship: part_of GO:0003157 ! endocardium development created_by: dph creation_date: 2010-06-03T09:18:02Z [Term] id: GO:0061154 name: endothelial tube morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a tube are generated and organized from an endothelium. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells." [GOC:dph, GOC:yaf] is_a: GO:0003159 ! morphogenesis of an endothelium is_a: GO:0060562 ! epithelial tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003915 ! endothelial tube relationship: results_in_morphogenesis_of UBERON:0003915 ! endothelial tube created_by: dph creation_date: 2010-06-15T09:05:00Z [Term] id: GO:0061155 name: pulmonary artery endothelial tube morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a tube are generated and organized from the pulmonary artery endothelium. An pulmonary artery endothelium is an epithelium that lines the pulmonary artery." [GOC:dph, GOC:yaf] is_a: GO:0061154 ! endothelial tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0005317 ! pulmonary artery endothelium relationship: part_of GO:0061156 ! pulmonary artery morphogenesis relationship: results_in_morphogenesis_of UBERON:0005317 ! pulmonary artery endothelium created_by: dph creation_date: 2010-06-15T09:09:04Z [Term] id: GO:0061156 name: pulmonary artery morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the pulmonary artery are generated and organized. The pulmonary artery is the artery that carries blood from the heart to the lungs." [GOC:dph, GOC:yaf] is_a: GO:0048844 ! artery morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002012 ! pulmonary artery relationship: results_in_morphogenesis_of UBERON:0002012 ! pulmonary artery created_by: dph creation_date: 2010-06-15T09:13:47Z [Term] id: GO:0061181 name: regulation of chondrocyte development namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate." [GOC:BHF, GOC:dph] is_a: GO:0032330 ! regulation of chondrocyte differentiation is_a: GO:0060284 ! regulation of cell development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002063 ! chondrocyte development relationship: regulates GO:0002063 ! chondrocyte development created_by: dph creation_date: 2010-07-14T08:28:52Z [Term] id: GO:0061182 name: negative regulation of chondrocyte development namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate." [GOC:BHF, GOC:dph] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0032331 ! negative regulation of chondrocyte differentiation is_a: GO:0061181 ! regulation of chondrocyte development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002063 ! chondrocyte development relationship: negatively_regulates GO:0002063 ! chondrocyte development created_by: dph creation_date: 2010-07-14T08:33:05Z [Term] id: GO:0061183 name: regulation of dermatome development namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin." [GOC:BHF, GOC:dph] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0061054 ! dermatome development relationship: regulates GO:0061054 ! dermatome development created_by: dph creation_date: 2010-07-14T08:40:26Z [Term] id: GO:0061184 name: positive regulation of dermatome development namespace: biological_process def: "Any process that increases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin." [GOC:BHF, GOC:dph] is_a: GO:0040019 ! positive regulation of embryonic development is_a: GO:0061183 ! regulation of dermatome development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0061054 ! dermatome development relationship: positively_regulates GO:0061054 ! dermatome development created_by: dph creation_date: 2010-07-14T08:42:03Z [Term] id: GO:0061185 name: negative regulation of dermatome development namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin." [GOC:BHF, GOC:dph] is_a: GO:0045992 ! negative regulation of embryonic development is_a: GO:0061183 ! regulation of dermatome development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0061054 ! dermatome development relationship: negatively_regulates GO:0061054 ! dermatome development created_by: dph creation_date: 2010-07-14T08:43:08Z [Term] id: GO:0061189 name: positive regulation of sclerotome development namespace: biological_process def: "Any process that increases the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra." [GOC:BHF, GOC:dph] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0061190 ! regulation of sclerotome development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0061056 ! sclerotome development relationship: positively_regulates GO:0061056 ! sclerotome development created_by: dph creation_date: 2010-07-14T09:17:23Z [Term] id: GO:0061190 name: regulation of sclerotome development namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra." [GOC:dph] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0061056 ! sclerotome development relationship: regulates GO:0061056 ! sclerotome development created_by: dph creation_date: 2010-07-14T09:19:47Z [Term] id: GO:0061205 name: paramesonephric duct development namespace: biological_process def: "The process whose specific outcome is the progression of the paramesonephric duct over time, from its formation to the mature structure. Mullerian ducts (or paramesonephric ducts) are paired ducts of the embryo that run down the lateral sides of the urogenital ridge and terminate at the mullerian eminence in the primitive urogenital sinus. In the female, they will develop to form the fallopian tubes, uterus, cervix, and the upper portion of the vagina; in the male, they are lost. These ducts are made of tissue of mesodermal origin." [GOC:dph, GOC:yaf] synonym: "Mullerian duct development" EXACT [GOC:dph] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0035295 ! tube development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003890 ! Mullerian duct relationship: results_in_development_of UBERON:0003890 ! Mullerian duct created_by: dph creation_date: 2010-07-30T10:54:47Z [Term] id: GO:0061206 name: mesonephros morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the mesonephros are generated and organized." [GOC:mtg_kidney_jan10] synonym: "Wolffian body morphogenesis" EXACT [GOC:dph] is_a: GO:0060993 ! kidney morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000080 ! mesonephros relationship: part_of GO:0001823 ! mesonephros development relationship: results_in_morphogenesis_of UBERON:0000080 ! mesonephros created_by: dph creation_date: 2010-08-17T03:11:10Z [Term] id: GO:0061208 name: cell differentiation involved in mesonephros development namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephros as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] is_a: GO:0061005 ! cell differentiation involved in kidney development intersection_of: GO:0030154 ! cell differentiation intersection_of: part_of GO:0001823 ! mesonephros development relationship: part_of GO:0001823 ! mesonephros development created_by: dph creation_date: 2010-08-17T03:21:23Z [Term] id: GO:0061209 name: cell proliferation involved in mesonephros development namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of the population in the mesonephros." [GOC:mtg_kidney_jan10] is_a: GO:0072111 ! cell proliferation involved in kidney development intersection_of: GO:0008283 ! cell population proliferation intersection_of: part_of GO:0001823 ! mesonephros development relationship: part_of GO:0001823 ! mesonephros development created_by: dph creation_date: 2010-08-17T03:22:46Z [Term] id: GO:0061210 name: cell-cell signaling involved in mesonephros development namespace: biological_process def: "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mesonephros over time, from its formation to the mature organ." [GOC:mtg_kidney_jan10] synonym: "cell-cell signalling involved in mesonephros development" EXACT [GOC:mah] is_a: GO:0060995 ! cell-cell signaling involved in kidney development intersection_of: GO:0007267 ! cell-cell signaling intersection_of: part_of GO:0001823 ! mesonephros development relationship: part_of GO:0001823 ! mesonephros development created_by: dph creation_date: 2010-08-17T03:24:08Z [Term] id: GO:0061211 name: mesonephric collecting duct development namespace: biological_process def: "The process whose specific outcome is the progression of a collecting duct in the mesonephros over time, from its formation to the mature structure. The collecting duct regulates water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder." [GOC:mtg_kidney_jan10] is_a: GO:0072044 ! collecting duct development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005319 ! mesonephric collecting duct relationship: part_of GO:0001823 ! mesonephros development relationship: results_in_development_of UBERON:0005319 ! mesonephric collecting duct created_by: dph creation_date: 2010-08-17T03:25:51Z [Term] id: GO:0061213 name: positive regulation of mesonephros development namespace: biological_process def: "Any process that increases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10] is_a: GO:0061217 ! regulation of mesonephros development is_a: GO:0090184 ! positive regulation of kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001823 ! mesonephros development relationship: positively_regulates GO:0001823 ! mesonephros development created_by: dph creation_date: 2010-08-17T03:39:35Z [Term] id: GO:0061214 name: mesonephric smooth muscle tissue development namespace: biological_process def: "The process whose specific outcome is the progression of smooth muscle in the mesonephros over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10] is_a: GO:0072194 ! kidney smooth muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005321 ! mesonephric smooth muscle tissue relationship: part_of GO:0001823 ! mesonephros development relationship: results_in_development_of UBERON:0005321 ! mesonephric smooth muscle tissue created_by: dph creation_date: 2010-08-17T03:29:54Z [Term] id: GO:0061215 name: mesonephric nephron development namespace: biological_process def: "The process whose specific outcome is the progression of a nephron in the mesonephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney." [GOC:mtg_kidney_jan10] is_a: GO:0072006 ! nephron development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005322 ! mesonephric nephron relationship: part_of GO:0001823 ! mesonephros development relationship: results_in_development_of UBERON:0005322 ! mesonephric nephron created_by: dph creation_date: 2010-08-17T03:31:08Z [Term] id: GO:0061217 name: regulation of mesonephros development namespace: biological_process def: "Any process that modulates the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10] is_a: GO:0090183 ! regulation of kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001823 ! mesonephros development relationship: regulates GO:0001823 ! mesonephros development created_by: dph creation_date: 2010-08-17T03:35:31Z [Term] id: GO:0061218 name: negative regulation of mesonephros development namespace: biological_process def: "Any process that decreases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10] is_a: GO:0061217 ! regulation of mesonephros development is_a: GO:0090185 ! negative regulation of kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001823 ! mesonephros development relationship: negatively_regulates GO:0001823 ! mesonephros development created_by: dph creation_date: 2010-08-17T03:43:06Z [Term] id: GO:0061219 name: mesonephric mesenchyme development namespace: biological_process def: "The biological process whose specific outcome is the progression of a mesonephric mesenchyme from an initial condition to its mature state. This process begins with the formation of mesonephric mesenchyme and ends with the mature structure. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros." [GOC:mtg_kidney_jan10] is_a: GO:0072074 ! kidney mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005323 ! mesonephric mesenchyme relationship: part_of GO:0001823 ! mesonephros development relationship: results_in_development_of UBERON:0005323 ! mesonephric mesenchyme created_by: dph creation_date: 2010-08-17T03:45:44Z [Term] id: GO:0061221 name: mesonephric mesenchyme morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a mesonephric mesenchymal tissue are generated and organized. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros." [GOC:mtg_kidney_jan10] is_a: GO:0072131 ! kidney mesenchyme morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0005323 ! mesonephric mesenchyme relationship: part_of GO:0061219 ! mesonephric mesenchyme development relationship: results_in_morphogenesis_of UBERON:0005323 ! mesonephric mesenchyme created_by: dph creation_date: 2010-08-19T01:17:38Z [Term] id: GO:0061227 name: pattern specification involved in mesonephros development namespace: biological_process def: "Any developmental process that results in the creation of defined areas or spaces within the mesonephros to which cells respond and eventually are instructed to differentiate." [GOC:mtg_kidney_jan10] synonym: "mesonephros pattern formation" RELATED [GOC:mtg_kidney_jan10] synonym: "mesonephros pattern specification" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0061004 ! pattern specification involved in kidney development intersection_of: GO:0007389 ! pattern specification process intersection_of: part_of GO:0001823 ! mesonephros development relationship: part_of GO:0001823 ! mesonephros development created_by: dph creation_date: 2010-08-19T02:22:22Z [Term] id: GO:0061228 name: mesonephric nephron morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the mesonephric nephron are generated and organized. A mesonephric nephron is the functional unit of the mesonephros." [GOC:mtg_kidney_jan10] is_a: GO:0072028 ! nephron morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0005322 ! mesonephric nephron relationship: part_of GO:0061206 ! mesonephros morphogenesis relationship: part_of GO:0061215 ! mesonephric nephron development relationship: results_in_morphogenesis_of UBERON:0005322 ! mesonephric nephron created_by: dph creation_date: 2010-08-19T02:26:24Z [Term] id: GO:0061235 name: mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis namespace: biological_process def: "The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the mesonephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells." [GOC:mtg_kidney_jan10] is_a: GO:0072038 ! mesenchymal stem cell maintenance involved in nephron morphogenesis relationship: part_of GO:0061228 ! mesonephric nephron morphogenesis created_by: dph creation_date: 2010-08-19T02:57:11Z [Term] id: GO:0061241 name: mesonephric nephron epithelium development namespace: biological_process def: "The process whose specific outcome is the progression of the mesonephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The mesonephric nephron epithelium is a tissue that covers the surface of a nephron in the mesonephros." [GOC:mtg_kidney_jan10] is_a: GO:0072009 ! nephron epithelium development is_a: GO:0072163 ! mesonephric epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005330 ! mesonephric nephron epithelium relationship: part_of GO:0061215 ! mesonephric nephron development relationship: results_in_development_of UBERON:0005330 ! mesonephric nephron epithelium created_by: dph creation_date: 2010-08-19T03:11:59Z [Term] id: GO:0061243 name: mesonephric renal vesicle morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the mesonephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the mesonephric nephron epithelium, and is formed by the condensation of mesenchymal cells." [GOC:mtg_kidney_jan10] is_a: GO:0072077 ! renal vesicle morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0005331 ! mesonephric renal vesicle relationship: part_of GO:0061228 ! mesonephric nephron morphogenesis relationship: results_in_morphogenesis_of UBERON:0005331 ! mesonephric renal vesicle created_by: dph creation_date: 2010-08-19T03:20:21Z [Term] id: GO:0061261 name: mesenchymal to epithelial transition involved in mesonephros morphogenesis namespace: biological_process def: "A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephros." [GOC:mtg_kidney_jan10] synonym: "mesonephric mesenchyme to epithelial transition" RELATED [GOC:mtg_kidney_jan10] is_a: GO:0035850 ! epithelial cell differentiation involved in kidney development is_a: GO:0060231 ! mesenchymal to epithelial transition is_a: GO:0061208 ! cell differentiation involved in mesonephros development intersection_of: GO:0060231 ! mesenchymal to epithelial transition intersection_of: part_of GO:0061206 ! mesonephros morphogenesis relationship: part_of GO:0061206 ! mesonephros morphogenesis created_by: dph creation_date: 2010-08-30T02:35:15Z [Term] id: GO:0061262 name: mesonephric renal vesicle formation namespace: biological_process def: "The developmental process pertaining to the initial formation of the mesonephros." [GOC:mtg_kidney_jan10] synonym: "mesonephros formation" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0072033 ! renal vesicle formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0005331 ! mesonephric renal vesicle relationship: part_of GO:0061243 ! mesonephric renal vesicle morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0005331 ! mesonephric renal vesicle created_by: dph creation_date: 2010-08-30T02:41:20Z [Term] id: GO:0061271 name: mesenchymal to epithelial transition involved in mesonephric renal vesicle formation namespace: biological_process def: "A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephric renal vesicle." [GOC:mtg_kidney_jan10] is_a: GO:0061261 ! mesenchymal to epithelial transition involved in mesonephros morphogenesis is_a: GO:0072036 ! mesenchymal to epithelial transition involved in renal vesicle formation intersection_of: GO:0060231 ! mesenchymal to epithelial transition intersection_of: part_of GO:0061262 ! mesonephric renal vesicle formation relationship: part_of GO:0061262 ! mesonephric renal vesicle formation created_by: dph creation_date: 2010-08-30T03:26:30Z [Term] id: GO:0061285 name: mesonephric capsule development namespace: biological_process def: "The progression of the mesonephric capsule over time, from its formation to the mature structure. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue." [GOC:mtg_kidney_jan10] is_a: GO:0072127 ! renal capsule development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0006170 ! mesonephric capsule relationship: part_of GO:0001823 ! mesonephros development relationship: results_in_development_of UBERON:0006170 ! mesonephric capsule created_by: dph creation_date: 2010-09-02T01:50:06Z [Term] id: GO:0061286 name: mesonephric capsule morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the mesonephric capsule are generated and organized. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage." [GOC:mtg_kidney_jan10] is_a: GO:0072128 ! renal capsule morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0006170 ! mesonephric capsule relationship: part_of GO:0061285 ! mesonephric capsule development relationship: results_in_morphogenesis_of UBERON:0006170 ! mesonephric capsule created_by: dph creation_date: 2010-09-02T01:53:31Z [Term] id: GO:0061287 name: mesonephric capsule formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a mesonephric capsule from unspecified parts. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage." [GOC:mtg_kidney_jan10] is_a: GO:0072129 ! renal capsule formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0006170 ! mesonephric capsule relationship: part_of GO:0061286 ! mesonephric capsule morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0006170 ! mesonephric capsule created_by: dph creation_date: 2010-09-02T01:55:03Z [Term] id: GO:0061295 name: regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis namespace: biological_process def: "Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] synonym: "regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis" NARROW [] synonym: "regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis" EXACT [] is_a: GO:0072039 ! regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1901146 ! mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis relationship: regulates GO:0061235 ! mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis relationship: regulates GO:1901146 ! mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis created_by: dph creation_date: 2010-09-06T09:48:56Z [Term] id: GO:0061296 name: negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis namespace: biological_process def: "Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] synonym: "negative regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis" NARROW [] synonym: "negative regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis" EXACT [] is_a: GO:0061218 ! negative regulation of mesonephros development is_a: GO:0061295 ! regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis is_a: GO:0072040 ! negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1901146 ! mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis relationship: negatively_regulates GO:0061235 ! mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis relationship: negatively_regulates GO:1901146 ! mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis created_by: dph creation_date: 2010-09-06T09:54:49Z [Term] id: GO:0061297 name: positive regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis namespace: biological_process def: "Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] synonym: "positive regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis" NARROW [] synonym: "positive regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis" EXACT [] is_a: GO:0061213 ! positive regulation of mesonephros development is_a: GO:0061295 ! regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis is_a: GO:0072041 ! positive regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1901146 ! mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis relationship: positively_regulates GO:0061235 ! mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis relationship: positively_regulates GO:1901146 ! mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis created_by: dph creation_date: 2010-09-06T09:58:59Z [Term] id: GO:0061298 name: retina vasculature development in camera-type eye namespace: biological_process def: "The process whose specific outcome is the progression of the vasculature of the retina over time, from its formation to the mature structure." [GOC:BHF, GOC:dph] synonym: "retinal vasculature development" EXACT [GOC:dph] is_a: GO:0001944 ! vasculature development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004864 ! vasculature of retina relationship: part_of GO:0060041 ! retina development in camera-type eye relationship: results_in_development_of UBERON:0004864 ! vasculature of retina created_by: dph creation_date: 2010-09-06T03:27:06Z [Term] id: GO:0061299 name: retina vasculature morphogenesis in camera-type eye namespace: biological_process def: "The process in which the vasculature of the retina is generated and organized." [GOC:BHF, GOC:dph] synonym: "retinal vasculature morphogenesis" EXACT [GOC:dph] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0004864 ! vasculature of retina relationship: part_of GO:0061298 ! retina vasculature development in camera-type eye relationship: results_in_morphogenesis_of UBERON:0004864 ! vasculature of retina created_by: dph creation_date: 2010-09-06T03:28:25Z [Term] id: GO:0061303 name: cornea development in camera-type eye namespace: biological_process def: "The progression of the cornea over time, from its formation to the mature structure. The cornea is the transparent structure that covers the anterior of the eye." [GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000964 ! cornea relationship: part_of GO:0043010 ! camera-type eye development relationship: results_in_development_of UBERON:0000964 ! cornea created_by: dph creation_date: 2010-09-14T02:09:08Z [Term] id: GO:0061304 name: retinal blood vessel morphogenesis namespace: biological_process def: "The process whose specific outcome is the progression of a blood vessel of the retina over time, from its formation to the mature structure." [GOC:BHF, GOC:dph] is_a: GO:0048514 ! blood vessel morphogenesis is_a: GO:0061299 ! retina vasculature morphogenesis in camera-type eye intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003501 ! retina blood vessel relationship: results_in_morphogenesis_of UBERON:0003501 ! retina blood vessel created_by: dph creation_date: 2010-09-16T09:02:59Z [Term] id: GO:0061307 name: cardiac neural crest cell differentiation involved in heart development namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a cardiac neural crest cell that will migrate to the heart and contribute to its development. Cardiac neural crest cells are specialized cells that migrate toward the heart from the third, fourth and sixth pharyngeal arches." [GOC:dph, GOC:mtg_heart, PMID:19705442] is_a: GO:0014033 ! neural crest cell differentiation is_a: GO:0035051 ! cardiocyte differentiation intersection_of: GO:0014033 ! neural crest cell differentiation intersection_of: part_of GO:0007507 ! heart development created_by: dph creation_date: 2010-09-23T08:50:56Z [Term] id: GO:0061308 name: cardiac neural crest cell development involved in heart development namespace: biological_process def: "The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the development of the heart." [GOC:dph, GOC:mtg_heart] is_a: GO:0014032 ! neural crest cell development intersection_of: GO:0014032 ! neural crest cell development intersection_of: part_of GO:0007507 ! heart development relationship: part_of GO:0061307 ! cardiac neural crest cell differentiation involved in heart development created_by: dph creation_date: 2010-09-23T09:01:49Z [Term] id: GO:0061309 name: cardiac neural crest cell development involved in outflow tract morphogenesis namespace: biological_process def: "The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the shaping of the outflow tract." [GOC:dph, GOC:mtg_heart] is_a: GO:0061308 ! cardiac neural crest cell development involved in heart development intersection_of: GO:0014032 ! neural crest cell development intersection_of: part_of GO:0003151 ! outflow tract morphogenesis relationship: part_of GO:0003151 ! outflow tract morphogenesis created_by: dph creation_date: 2010-09-23T09:08:37Z [Term] id: GO:0061323 name: cell proliferation involved in heart morphogenesis namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the heart." [GOC:dph, GOC:mtg_heart] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: part_of GO:0003007 ! heart morphogenesis relationship: part_of GO:0003007 ! heart morphogenesis created_by: dph creation_date: 2010-09-28T09:05:26Z [Term] id: GO:0061325 name: cell proliferation involved in outflow tract morphogenesis namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the outflow tract." [GOC:dph, GOC:mtg_heart] is_a: GO:0061323 ! cell proliferation involved in heart morphogenesis intersection_of: GO:0008283 ! cell population proliferation intersection_of: part_of GO:0003151 ! outflow tract morphogenesis relationship: part_of GO:0003151 ! outflow tract morphogenesis created_by: dph creation_date: 2010-09-28T09:29:30Z [Term] id: GO:0061326 name: renal tubule development namespace: biological_process def: "The progression of the renal tubule over time from its formation to the mature form. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis." [GOC:dph, GOC:mtg_kidney_jan10] is_a: GO:0035295 ! tube development is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0009773 ! renal tubule relationship: part_of GO:0072001 ! renal system development relationship: results_in_development_of UBERON:0009773 ! renal tubule created_by: dph creation_date: 2010-09-28T12:50:43Z [Term] id: GO:0061333 name: renal tubule morphogenesis namespace: biological_process def: "The process in which the renal tubule is generated by specification of cell fate, through the maintenance of cell polarity, regulated cell proliferation and morphogenetic cell rearrangements, shape changes and growth. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis." [GOC:dph, GOC:mtg_kidney_jan10] is_a: GO:0060562 ! epithelial tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0009773 ! renal tubule relationship: part_of GO:0061326 ! renal tubule development relationship: results_in_morphogenesis_of UBERON:0009773 ! renal tubule created_by: dph creation_date: 2010-09-28T01:43:04Z [Term] id: GO:0061337 name: cardiac conduction namespace: biological_process def: "Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles." [GOC:dph] is_a: GO:0008016 ! regulation of heart contraction created_by: dph creation_date: 2010-09-29T08:46:05Z [Term] id: GO:0061343 name: cell adhesion involved in heart morphogenesis namespace: biological_process def: "The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the shaping of the heart." [GOC:dph, GOC:mtg_heart, PMID:16860783] is_a: GO:0007155 ! cell adhesion intersection_of: GO:0007155 ! cell adhesion intersection_of: part_of GO:0003007 ! heart morphogenesis relationship: part_of GO:0003007 ! heart morphogenesis created_by: dph creation_date: 2010-09-29T11:34:06Z [Term] id: GO:0061344 name: regulation of cell adhesion involved in heart morphogenesis namespace: biological_process def: "Any process that modulates the extent of cell adhesion contributing to the shaping of the heart." [GOC:dph, GOC:mtg_heart, PMID:16860783] is_a: GO:0030155 ! regulation of cell adhesion intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0061343 ! cell adhesion involved in heart morphogenesis relationship: regulates GO:0061343 ! cell adhesion involved in heart morphogenesis created_by: dph creation_date: 2010-09-29T11:35:27Z [Term] id: GO:0061351 name: neural precursor cell proliferation namespace: biological_process def: "The multiplication or reproduction of neural precursor cells, resulting in the expansion of a cell population. A neural precursor cell is either a nervous system stem cell or a nervous system progenitor cell." [GOC:dph, GOC:yaf] is_a: GO:0008283 ! cell population proliferation created_by: dph creation_date: 2010-10-01T11:06:04Z [Term] id: GO:0061383 name: trabecula morphogenesis namespace: biological_process def: "The process of shaping a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue." [GOC:dph] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000440 ! trabecula relationship: results_in_morphogenesis_of UBERON:0000440 ! trabecula created_by: dph creation_date: 2010-12-02T08:51:45Z [Term] id: GO:0061384 name: heart trabecula morphogenesis namespace: biological_process def: "The process of shaping a trabecula in the heart. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue." [GOC:dph] is_a: GO:0061383 ! trabecula morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002511 ! trabecula carnea relationship: results_in_morphogenesis_of UBERON:0002511 ! trabecula carnea created_by: dph creation_date: 2010-12-02T08:54:20Z [Term] id: GO:0061385 name: fibroblast proliferation involved in heart morphogenesis namespace: biological_process def: "The multiplication or reproduction of fibroblasts, resulting in the expansion of a fibroblast population that contributes to the shaping of the heart." [GOC:dph] is_a: GO:0048144 ! fibroblast proliferation is_a: GO:0061323 ! cell proliferation involved in heart morphogenesis intersection_of: GO:0048144 ! fibroblast proliferation intersection_of: part_of GO:0003007 ! heart morphogenesis created_by: dph creation_date: 2011-02-10T01:41:59Z [Term] id: GO:0061437 name: renal system vasculature development namespace: biological_process def: "The process whose specific outcome is the progression of vasculature of the renal system over time, from its formation to the mature structure." [GOC:dph, GOC:mtg_kidney_jan10, PMID:11891195] is_a: GO:0001944 ! vasculature development relationship: part_of GO:0072001 ! renal system development created_by: dph creation_date: 2012-03-08T12:16:24Z [Term] id: GO:0061438 name: renal system vasculature morphogenesis namespace: biological_process def: "The process in which the renal system vasculature is generated and organized. Morphogenesis pertains to the creation of form." [GOC:dph, GOC:mtg_kidney_jan10, PMID:11891195] is_a: GO:0009653 ! anatomical structure morphogenesis relationship: part_of GO:0061437 ! renal system vasculature development created_by: dph creation_date: 2012-03-08T12:21:56Z [Term] id: GO:0061439 name: kidney vasculature morphogenesis namespace: biological_process def: "The process in which the kidney vasculature is generated and organized. Morphogenesis pertains to the creation of form." [GOC:dph, GOC:mtg_kidney_jan10] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0006544 ! kidney vasculature relationship: part_of GO:0061438 ! renal system vasculature morphogenesis relationship: part_of GO:0061440 ! kidney vasculature development relationship: results_in_morphogenesis_of UBERON:0006544 ! kidney vasculature created_by: dph creation_date: 2012-03-08T12:30:11Z [Term] id: GO:0061440 name: kidney vasculature development namespace: biological_process def: "The process whose specific outcome is the progression of the vasculature of the kidney over time, from its formation to the mature structure." [GOC:dph, GOC:mtg_kidney_jan10, PMID:11891195] is_a: GO:0061437 ! renal system vasculature development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0006544 ! kidney vasculature relationship: part_of GO:0001822 ! kidney development relationship: results_in_development_of UBERON:0006544 ! kidney vasculature created_by: dph creation_date: 2012-03-08T12:39:09Z [Term] id: GO:0061441 name: renal artery morphogenesis namespace: biological_process def: "The process in which the anatomical structure of a renal artery is generated and organized. Renal arteries supply the kidneys with blood." [GOC:mtg_kidney_jan10, PMID:11891195] is_a: GO:0048844 ! artery morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001184 ! renal artery relationship: part_of GO:0061439 ! kidney vasculature morphogenesis relationship: results_in_morphogenesis_of UBERON:0001184 ! renal artery created_by: dph creation_date: 2012-03-08T12:42:09Z [Term] id: GO:0061448 name: connective tissue development namespace: biological_process def: "The progression of a connective tissue over time, from its formation to the mature structure." [GOC:BHF] is_a: GO:0009888 ! tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002384 ! connective tissue relationship: results_in_development_of UBERON:0002384 ! connective tissue created_by: dph creation_date: 2012-03-22T12:53:41Z [Term] id: GO:0061450 name: trophoblast cell migration namespace: biological_process def: "Trophoblast cell migration that is accomplished by extension and retraction of a pseudopodium. Trophoblast cells line the outside of the blastocyst." [GOC:dph] is_a: GO:0001667 ! ameboidal-type cell migration is_a: GO:0022414 ! reproductive process intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000351 ! trophoblast cell relationship: part_of GO:0007566 ! embryo implantation relationship: results_in_movement_of CL:0000351 ! trophoblast cell created_by: dph creation_date: 2012-07-10T08:38:37Z [Term] id: GO:0061453 name: interstitial cell of Cajal differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of an interstitial cell of Cajal. An interstitial cell of Cajal is an intestinal neuroepithelial cell that serves as a pacemaker to trigger gut contraction." [GOC:dph] synonym: "ICC differentiation" RELATED [GOC:dph] is_a: GO:0060563 ! neuroepithelial cell differentiation is_a: GO:0060575 ! intestinal epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0002088 ! interstitial cell of Cajal relationship: results_in_acquisition_of_features_of CL:0002088 ! interstitial cell of Cajal created_by: dph creation_date: 2012-07-20T08:20:50Z [Term] id: GO:0061458 name: reproductive system development namespace: biological_process def: "The progression of the reproductive system over time from its formation to the mature structure. The reproductive system consists of the organs that function in reproduction." [GOC:dph] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000990 ! reproductive system relationship: results_in_development_of UBERON:0000990 ! reproductive system created_by: dph creation_date: 2012-08-22T17:47:53Z [Term] id: GO:0061469 name: regulation of type B pancreatic cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of type B pancreatic cell proliferation." [GOC:dph] is_a: GO:0050678 ! regulation of epithelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0044342 ! type B pancreatic cell proliferation relationship: regulates GO:0044342 ! type B pancreatic cell proliferation created_by: dph creation_date: 2012-11-01T13:16:23Z [Term] id: GO:0061484 name: hematopoietic stem cell homeostasis namespace: biological_process def: "Any biological process involved in the maintenance of the steady-state number of hematopoietic stem cells within a population of cells." [GOC:dph, PMID:21508411] is_a: GO:0048872 ! homeostasis of number of cells intersection_of: GO:0048872 ! homeostasis of number of cells intersection_of: acts_on_population_of CL:0000037 ! hematopoietic stem cell relationship: acts_on_population_of CL:0000037 ! hematopoietic stem cell created_by: dph creation_date: 2012-12-04T09:41:02Z [Term] id: GO:0061512 name: protein localization to cilium namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within a cilium." [GOC:dph] is_a: GO:0033365 ! protein localization to organelle intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0005929 ! cilium relationship: has_target_end_location GO:0005929 ! cilium relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3312 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4890 property_value: RO:0002161 NCBITaxon:5782 created_by: dph creation_date: 2013-03-22T15:41:44Z [Term] id: GO:0061515 name: myeloid cell development namespace: biological_process def: "The process whose specific outcome is the progression of a myeloid cell over time, from its formation to the mature structure." [GOC:dph] is_a: GO:0030097 ! hemopoiesis intersection_of: GO:0048468 ! cell development intersection_of: results_in_development_of CL:0000763 ! myeloid cell relationship: part_of GO:0030099 ! myeloid cell differentiation relationship: results_in_development_of CL:0000763 ! myeloid cell created_by: dph creation_date: 2013-04-18T13:03:16Z [Term] id: GO:0061523 name: cilium disassembly namespace: biological_process def: "A cellular process that results in the breakdown of a cilium." [GOC:cilia, GOC:dph, PMID:17604723, PMID:27350441] comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. synonym: "cilium resorption" EXACT [GOC:dph] is_a: GO:0044782 ! cilium organization is_a: GO:1903008 ! organelle disassembly intersection_of: GO:0022411 ! cellular component disassembly intersection_of: results_in_disassembly_of GO:0005929 ! cilium relationship: results_in_disassembly_of GO:0005929 ! cilium created_by: dph creation_date: 2013-04-18T14:59:59Z [Term] id: GO:0061525 name: hindgut development namespace: biological_process def: "The process whose specific outcome is the progression of the hindgut over time, from its formation to the mature structure. The hindgut is part of the alimentary canal that lies posterior to the midgut." [GOC:dph] is_a: GO:0048565 ! digestive tract development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001046 ! hindgut relationship: results_in_development_of UBERON:0001046 ! hindgut created_by: dph creation_date: 2013-06-14T11:22:21Z [Term] id: GO:0061526 name: acetylcholine secretion namespace: biological_process def: "The regulated release of acetylcholine by a cell." [GOC:dph] is_a: GO:0015870 ! acetylcholine transport is_a: GO:0023061 ! signal release intersection_of: GO:0046903 ! secretion intersection_of: has_primary_input CHEBI:15355 ! acetylcholine created_by: dph creation_date: 2013-06-21T15:40:39Z [Term] id: GO:0061533 name: norepinephrine secretion, neurotransmission namespace: biological_process def: "The regulated release of norepinephrine by a cell, in which the norepinephrine acts as a neurotransmitter." [GOC:dph] synonym: "noradrenaline secretion, neurotransmission" EXACT [GOC:dph] is_a: GO:0048243 ! norepinephrine secretion is_a: GO:0160043 ! catecholamine secretion, neurotransmission intersection_of: GO:0007269 ! neurotransmitter secretion intersection_of: has_primary_input CHEBI:72587 ! (R)-noradrenaline(1+) created_by: dph creation_date: 2013-06-21T16:05:08Z [Term] id: GO:0061548 name: ganglion development namespace: biological_process def: "The process whose specific outcome is the progression of a ganglion over time, from its formation to the mature structure." [GOC:dph] synonym: "ganglia development" RELATED [GOC:dph] synonym: "gangliogenesis" NARROW [GOC:BHF, GOC:rl] is_a: GO:0009888 ! tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000045 ! ganglion relationship: part_of GO:0007399 ! nervous system development relationship: results_in_development_of UBERON:0000045 ! ganglion created_by: dph creation_date: 2013-07-10T08:36:12Z [Term] id: GO:0061549 name: sympathetic ganglion development namespace: biological_process def: "The process whose specific outcome is the progression of a sympathetic ganglion over time, from its formation to the mature structure." [GOC:BHF, GOC:rl] synonym: "sympathetic ganglia development" RELATED [GOC:dph] is_a: GO:0061548 ! ganglion development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001806 ! sympathetic ganglion relationship: part_of GO:0048485 ! sympathetic nervous system development relationship: results_in_development_of UBERON:0001806 ! sympathetic ganglion created_by: dph creation_date: 2013-07-10T08:38:01Z [Term] id: GO:0061550 name: cranial ganglion development namespace: biological_process def: "The process whose specific outcome is the progression of a cranial ganglion over time, from its formation to the mature structure." [GOC:dph] synonym: "cranial ganglia development" RELATED [GOC:dph] is_a: GO:0061548 ! ganglion development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001714 ! cranial ganglion relationship: part_of GO:0021545 ! cranial nerve development relationship: results_in_development_of UBERON:0001714 ! cranial ganglion created_by: dph creation_date: 2013-07-10T08:40:14Z [Term] id: GO:0061551 name: trigeminal ganglion development namespace: biological_process def: "The process whose specific outcome is the progression of a trigeminal ganglion over time, from its formation to the mature structure." [GOC:dph] synonym: "trigeminal ganglia development" RELATED [GOC:dph] is_a: GO:0061550 ! cranial ganglion development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001675 ! trigeminal ganglion relationship: results_in_development_of UBERON:0001675 ! trigeminal ganglion created_by: dph creation_date: 2013-07-10T08:42:19Z [Term] id: GO:0061552 name: ganglion morphogenesis namespace: biological_process def: "The process in which the anatomical structures of ganglion are generated and organized." [GOC:dph] synonym: "ganglia morphogenesis" RELATED [GOC:dph] is_a: GO:0048729 ! tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000045 ! ganglion relationship: part_of GO:0061548 ! ganglion development relationship: results_in_morphogenesis_of UBERON:0000045 ! ganglion created_by: dph creation_date: 2013-07-10T08:44:57Z [Term] id: GO:0061553 name: ganglion maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for ganglion to attain its fully functional state." [GOC:dph] synonym: "ganglia maturation" RELATED [GOC:dph] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0071695 ! anatomical structure maturation intersection_of: results_in_maturation_of UBERON:0000045 ! ganglion relationship: part_of GO:0061548 ! ganglion development relationship: results_in_maturation_of UBERON:0000045 ! ganglion created_by: dph creation_date: 2013-07-10T08:45:59Z [Term] id: GO:0061554 name: ganglion formation namespace: biological_process def: "The process that gives rise to ganglion. This process pertains to the initial formation of a structure from unspecified parts." [GOC:dph] synonym: "ganglia formation" RELATED [GOC:dph] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0000045 ! ganglion relationship: part_of GO:0061552 ! ganglion morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0000045 ! ganglion created_by: dph creation_date: 2013-07-10T08:51:50Z [Term] id: GO:0061556 name: trigeminal ganglion morphogenesis namespace: biological_process def: "The process in which the anatomical structure of a trigeminal ganglion is generated and organized." [GOC:dph] synonym: "trigeminal ganglia morphogenesis" RELATED [GOC:dph] is_a: GO:0061559 ! cranial ganglion morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001675 ! trigeminal ganglion relationship: part_of GO:0021636 ! trigeminal nerve morphogenesis relationship: part_of GO:0061551 ! trigeminal ganglion development relationship: results_in_morphogenesis_of UBERON:0001675 ! trigeminal ganglion created_by: dph creation_date: 2013-07-10T08:57:12Z [Term] id: GO:0061557 name: trigeminal ganglion maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for a trigeminal ganglion to attain its fully functional state." [GOC:dph] synonym: "trigeminal ganglia maturation" RELATED [GOC:dph] is_a: GO:0061558 ! cranial ganglion maturation intersection_of: GO:0071695 ! anatomical structure maturation intersection_of: results_in_maturation_of UBERON:0001675 ! trigeminal ganglion relationship: part_of GO:0021635 ! trigeminal nerve maturation relationship: part_of GO:0061551 ! trigeminal ganglion development relationship: results_in_maturation_of UBERON:0001675 ! trigeminal ganglion created_by: dph creation_date: 2013-07-10T08:58:24Z [Term] id: GO:0061558 name: cranial ganglion maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for a cranial ganglion to attain its fully functional state." [GOC:dph] synonym: "cranial ganglia maturation" RELATED [GOC:dph] is_a: GO:0061553 ! ganglion maturation intersection_of: GO:0071695 ! anatomical structure maturation intersection_of: results_in_maturation_of UBERON:0001714 ! cranial ganglion relationship: part_of GO:0021605 ! cranial nerve maturation relationship: part_of GO:0061550 ! cranial ganglion development relationship: results_in_maturation_of UBERON:0001714 ! cranial ganglion created_by: dph creation_date: 2013-07-10T08:59:52Z [Term] id: GO:0061559 name: cranial ganglion morphogenesis namespace: biological_process def: "The process in which the anatomical structure of a cranial ganglion is generated and organized." [GOC:dph] synonym: "cranial ganglia morphogenesis" RELATED [GOC:dph] is_a: GO:0061552 ! ganglion morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001714 ! cranial ganglion relationship: part_of GO:0021602 ! cranial nerve morphogenesis relationship: part_of GO:0061550 ! cranial ganglion development relationship: results_in_morphogenesis_of UBERON:0001714 ! cranial ganglion created_by: dph creation_date: 2013-07-10T09:02:15Z [Term] id: GO:0061560 name: cranial ganglion formation namespace: biological_process def: "The process that gives rise to a cranial ganglion. This process pertains to the initial formation of a structure from unspecified parts." [GOC:dph] synonym: "cranial ganglia formation" RELATED [GOC:dph] is_a: GO:0061554 ! ganglion formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0001714 ! cranial ganglion relationship: part_of GO:0061559 ! cranial ganglion morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0001714 ! cranial ganglion created_by: dph creation_date: 2013-07-10T09:07:27Z [Term] id: GO:0061561 name: trigeminal ganglion formation namespace: biological_process def: "The process that gives rise to the trigeminal ganglion. This process pertains to the initial formation of a structure from unspecified parts." [GOC:dph] synonym: "trigeminal ganglia formation" RELATED [GOC:dph] is_a: GO:0061560 ! cranial ganglion formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0001675 ! trigeminal ganglion relationship: part_of GO:0061556 ! trigeminal ganglion morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0001675 ! trigeminal ganglion created_by: dph creation_date: 2013-07-10T09:08:13Z [Term] id: GO:0061572 name: actin filament bundle organization namespace: biological_process def: "A process that results in the assembly, arrangement of constituent parts, or disassembly of an actin filament bundle." [GOC:dph] synonym: "actin filament cable organization" RELATED [GOC:dph] is_a: GO:0007015 ! actin filament organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0032432 ! actin filament bundle relationship: results_in_organization_of GO:0032432 ! actin filament bundle created_by: dph creation_date: 2013-08-02T11:24:11Z [Term] id: GO:0061580 name: colon epithelial cell migration namespace: biological_process def: "The orderly movement of a colonic epithelial cell from one site to another, often during the development of a multicellular organism." [GOC:dph] is_a: GO:0061582 ! intestinal epithelial cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0011108 ! colon epithelial cell relationship: results_in_movement_of CL:0011108 ! colon epithelial cell created_by: dph creation_date: 2013-12-23T07:26:54Z [Term] id: GO:0061581 name: corneal epithelial cell migration namespace: biological_process def: "The orderly movement of a corneal epithelial cell from one site to another, often during the development of a multicellular organism." [GOC:dph] is_a: GO:0010631 ! epithelial cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000575 ! corneal epithelial cell relationship: results_in_movement_of CL:0000575 ! corneal epithelial cell created_by: dph creation_date: 2013-12-23T07:28:29Z [Term] id: GO:0061582 name: intestinal epithelial cell migration namespace: biological_process def: "The orderly movement of an intestinal epithelial cell from one site to another, often during the development of a multicellular organism." [GOC:dph] is_a: GO:0010631 ! epithelial cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0002563 ! intestinal epithelial cell relationship: results_in_movement_of CL:0002563 ! intestinal epithelial cell created_by: dph creation_date: 2013-12-23T07:30:55Z [Term] id: GO:0061626 name: pharyngeal arch artery morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a pharyngeal arch artery is generated and organized. The pharyngeal arch arteries are a series of six paired embryological vascular structures, the development of which give rise to several major arteries, such as the stapedial artery, the middle meningeal artery, the internal carotid artery and the pulmonary artery." [GOC:BHF, GOC:dph, PMID:20122914] synonym: "aortic arch artery morphogenesis" BROAD [GOC:dph] is_a: GO:0048844 ! artery morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0004363 ! pharyngeal arch artery relationship: part_of GO:0060037 ! pharyngeal system development relationship: results_in_morphogenesis_of UBERON:0004363 ! pharyngeal arch artery created_by: dph creation_date: 2014-05-09T15:34:06Z [Term] id: GO:0061682 name: seminal vesicle morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a seminal vesicle are generated and organized." [GOC:dph] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0022612 ! gland morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000998 ! seminal vesicle relationship: part_of GO:0061107 ! seminal vesicle development relationship: results_in_morphogenesis_of UBERON:0000998 ! seminal vesicle created_by: dph creation_date: 2015-03-04T13:33:49Z [Term] id: GO:0061683 name: branching involved in seminal vesicle morphogenesis namespace: biological_process def: "The process in which the branching structure of the seminal vesicle is generated and organized. A branch is a division or offshoot from a main stem." [GOC:dph, PMID:16916376] synonym: "gonecyst branching morphogenesis" EXACT [GOC:dph] synonym: "seminal gland branching morphogenesis" EXACT [GOC:dph] synonym: "seminal vesicle branching" EXACT [GOC:dph] synonym: "seminal vesicle branching morphogenesis" EXACT [GOC:dph] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0061138 ! morphogenesis of a branching epithelium intersection_of: GO:0061138 ! morphogenesis of a branching epithelium intersection_of: part_of GO:0061682 ! seminal vesicle morphogenesis relationship: part_of GO:0061108 ! seminal vesicle epithelium development relationship: part_of GO:0061682 ! seminal vesicle morphogenesis created_by: dph creation_date: 2015-03-04T13:39:47Z [Term] id: GO:0061687 name: detoxification of inorganic compound namespace: biological_process def: "Any process that reduces or removes the toxicity of inorganic compounds. These include transport of such compounds away from sensitive areas and to compartments or complexes whose purpose is sequestration of inorganic compounds." [GOC:vw] is_a: GO:0098754 ! detoxification intersection_of: GO:0098754 ! detoxification intersection_of: has_primary_input CHEBI:24835 ! inorganic molecular entity relationship: has_primary_input CHEBI:24835 ! inorganic molecular entity created_by: dph creation_date: 2015-03-09T09:16:23Z [Term] id: GO:0061695 name: transferase complex, transferring phosphorus-containing groups namespace: cellular_component def: "A transferase complex capable of catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor)." [GOC:bhm, GOC:dph] is_a: GO:1990234 ! transferase complex intersection_of: GO:0032991 ! protein-containing complex intersection_of: capable_of GO:0016772 ! transferase activity, transferring phosphorus-containing groups relationship: capable_of GO:0016772 ! transferase activity, transferring phosphorus-containing groups created_by: dph creation_date: 2015-05-06T11:22:38Z [Term] id: GO:0061792 name: secretory granule maturation namespace: biological_process def: "Steps required to transform an immature secretory vesicle into a mature secretory vesicle. Typically proceeds through homotypic membrane fusion and membrane remodeling." [GOC:bf, GOC:dph, GOC:PARL, PMID:16618809] is_a: GO:0033363 ! secretory granule organization is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of GO:0030141 ! secretory granule relationship: results_in_maturation_of GO:0030141 ! secretory granule created_by: dph creation_date: 2016-09-09T13:24:34Z [Term] id: GO:0061853 name: regulation of neuroblast migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of neuroblast migration." [PMID:23149556] is_a: GO:0030334 ! regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0097402 ! neuroblast migration relationship: regulates GO:0097402 ! neuroblast migration created_by: dph creation_date: 2017-03-08T18:17:07Z [Term] id: GO:0061854 name: positive regulation of neuroblast migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of neuroblast migration." [PMID:23149556] is_a: GO:0030335 ! positive regulation of cell migration is_a: GO:0061853 ! regulation of neuroblast migration intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0097402 ! neuroblast migration relationship: positively_regulates GO:0097402 ! neuroblast migration created_by: dph creation_date: 2017-03-08T18:22:30Z [Term] id: GO:0061855 name: negative regulation of neuroblast migration namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of neuroblast migration." [PMID:23149556] is_a: GO:0030336 ! negative regulation of cell migration is_a: GO:0061853 ! regulation of neuroblast migration intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0097402 ! neuroblast migration relationship: negatively_regulates GO:0097402 ! neuroblast migration created_by: dph creation_date: 2017-03-08T18:26:21Z [Term] id: GO:0061900 name: glial cell activation namespace: biological_process def: "A change in morphology and behavior of a glial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor." [GOC:aruk, GOC:bc, PMID:18723082] is_a: GO:0001775 ! cell activation intersection_of: GO:0001775 ! cell activation intersection_of: has_primary_input CL:0000125 ! glial cell relationship: has_primary_input CL:0000125 ! glial cell relationship: part_of GO:0150076 ! neuroinflammatory response created_by: dph creation_date: 2017-06-13T13:06:23Z [Term] id: GO:0061938 name: protein localization to somatodendritic compartment namespace: biological_process def: "A process in which a protein is transported to or maintained in a location within the somatodendritic compartment." [PMID:18341993] synonym: "somatodendritic protein localization" EXACT [] is_a: GO:0008104 ! protein localization intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0036477 ! somatodendritic compartment relationship: has_target_end_location GO:0036477 ! somatodendritic compartment created_by: dph creation_date: 2017-09-08T13:22:26Z [Term] id: GO:0061951 name: establishment of protein localization to plasma membrane namespace: biological_process def: "The directed movement of a protein to a specific location in a plasma membrane." [GOC:dph, GOC:vw] is_a: GO:0090150 ! establishment of protein localization to membrane intersection_of: GO:0045184 ! establishment of protein localization intersection_of: has_target_end_location GO:0005886 ! plasma membrane intersection_of: has_target_start_location GO:0005622 ! intracellular anatomical structure relationship: has_target_end_location GO:0005886 ! plasma membrane relationship: has_target_start_location GO:0005622 ! intracellular anatomical structure created_by: dph creation_date: 2017-10-26T12:55:15Z [Term] id: GO:0061971 name: replacement bone morphogenesis namespace: biological_process def: "The process in which bones are generated and organized as a result of the conversion of another structural tissue into bone." [PMID:29852585] is_a: GO:0060349 ! bone morphogenesis intersection_of: GO:0060349 ! bone morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0012075 ! replacement bone relationship: results_in_morphogenesis_of UBERON:0012075 ! replacement bone created_by: dph creation_date: 2018-02-12T18:10:59Z [Term] id: GO:0061972 name: dermal bone morphogenesis namespace: biological_process def: "The process in which bone which forms superficially in the organism are generated and organized." [PMID:12588850, PMID:15003632] is_a: GO:0061973 ! membrane bone morphogenesis intersection_of: GO:0060349 ! bone morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0008907 ! dermal bone relationship: results_in_morphogenesis_of UBERON:0008907 ! dermal bone created_by: dph creation_date: 2018-02-12T18:16:21Z [Term] id: GO:0061973 name: membrane bone morphogenesis namespace: biological_process def: "The process in which bone which forms deep in the organism are generated and organized." [PMID:14579374] is_a: GO:0060349 ! bone morphogenesis intersection_of: GO:0060349 ! bone morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0007842 ! membrane bone relationship: results_in_morphogenesis_of UBERON:0007842 ! membrane bone created_by: dph creation_date: 2018-02-12T18:21:09Z [Term] id: GO:0061983 name: meiosis II cell cycle process namespace: biological_process def: "A process that coontributes to the second meiotic division. The second meiotic division separates chromatids resulting in a haploid number of chromosomes." [PMID:29385397] synonym: "second meiotic division" EXACT [PMID:29385397] is_a: GO:1903046 ! meiotic cell cycle process created_by: dph creation_date: 2018-02-14T22:37:44Z [Term] id: GO:0062012 name: regulation of small molecule metabolic process namespace: biological_process def: "Any process that modulates the rate, frequency or extent of a small molecule metabolic process." [GOC:vw] synonym: "regulation of small molecule metabolism" EXACT [] is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0044281 ! small molecule metabolic process relationship: regulates GO:0044281 ! small molecule metabolic process created_by: dph creation_date: 2018-03-19T14:11:54Z [Term] id: GO:0062013 name: positive regulation of small molecule metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of a small molecule metabolic process." [GOC:vw] synonym: "positive regulation of small molecule metabolism" EXACT [] is_a: GO:0009893 ! positive regulation of metabolic process is_a: GO:0062012 ! regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0044281 ! small molecule metabolic process relationship: positively_regulates GO:0044281 ! small molecule metabolic process created_by: dph creation_date: 2018-03-19T14:25:10Z [Term] id: GO:0062014 name: negative regulation of small molecule metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of a small molecule metabolic process." [GOC:vw] synonym: "negative regulation of small molecule metabolism" EXACT [] is_a: GO:0009892 ! negative regulation of metabolic process is_a: GO:0062012 ! regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0044281 ! small molecule metabolic process relationship: negatively_regulates GO:0044281 ! small molecule metabolic process created_by: dph creation_date: 2018-03-19T14:27:23Z [Term] id: GO:0062023 name: collagen-containing extracellular matrix namespace: cellular_component def: "An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells." [GOC:BHF, GOC:rph, PMID:21123617] is_a: GO:0031012 ! extracellular matrix relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa created_by: dph creation_date: 2018-04-13T12:47:21Z [Term] id: GO:0062033 name: positive regulation of mitotic sister chromatid segregation namespace: biological_process def: "Any process that starts or increases the frequency, rate or extent of sister chromatid segregation during mitosis." [PMID:12773390] is_a: GO:0033047 ! regulation of mitotic sister chromatid segregation is_a: GO:0051984 ! positive regulation of chromosome segregation is_a: GO:2001252 ! positive regulation of chromosome organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0000070 ! mitotic sister chromatid segregation relationship: positively_regulates GO:0000070 ! mitotic sister chromatid segregation created_by: dph creation_date: 2018-04-23T14:32:23Z [Term] id: GO:0062094 name: stomach development namespace: biological_process def: "The process whose specific outcome is the progression of the stomach over time, from its formation to the mature structure. The stomach is an expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ." [PMID:11967278] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000945 ! stomach relationship: part_of GO:0048565 ! digestive tract development relationship: results_in_development_of UBERON:0000945 ! stomach created_by: dph creation_date: 2018-11-20T18:15:45Z [Term] id: GO:0062149 name: detection of stimulus involved in sensory perception of pain namespace: biological_process def: "The series of events involved in the perception of pain in which a stimulus is received and converted into a molecular signal." [PMID:19837031] is_a: GO:0050906 ! detection of stimulus involved in sensory perception intersection_of: GO:0051606 ! detection of stimulus intersection_of: part_of GO:0019233 ! sensory perception of pain relationship: part_of GO:0019233 ! sensory perception of pain created_by: dph creation_date: 2019-09-13T13:48:47Z [Term] id: GO:0062223 name: regulation of somatic muscle development namespace: biological_process def: "Any process that regulates the rate, frequency or extent of somatic muscle development." [PMID:16643882, PMID:25758712] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007525 ! somatic muscle development relationship: regulates GO:0007525 ! somatic muscle development created_by: dph creation_date: 2020-03-13T18:58:37Z [Term] id: GO:0062224 name: positive regulation of somatic muscle development namespace: biological_process def: "Any process that increases the rate, frequency or extent of somatic muscle development." [PMID:16643882, PMID:25758712] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0062223 ! regulation of somatic muscle development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007525 ! somatic muscle development relationship: positively_regulates GO:0007525 ! somatic muscle development created_by: dph creation_date: 2020-03-13T19:03:38Z [Term] id: GO:0062225 name: negative regulation of somatic muscle development namespace: biological_process def: "Any process that decreases the rate, frequency or extent of somatic muscle development." [PMID:16643882, PMID:25758712] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0062223 ! regulation of somatic muscle development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007525 ! somatic muscle development relationship: negatively_regulates GO:0007525 ! somatic muscle development created_by: dph creation_date: 2020-03-13T19:06:27Z [Term] id: GO:0062237 name: protein localization to postsynapse namespace: biological_process def: "Any process in which a protein is transported to, and/or maintained at the postsynapse, the part of a synapse that is part of the post-synaptic cell." [PMID:31189538] is_a: GO:0035418 ! protein localization to synapse intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0098794 ! postsynapse relationship: has_target_end_location GO:0098794 ! postsynapse created_by: dph creation_date: 2020-04-20T13:58:43Z [Term] id: GO:0065002 name: intracellular protein transmembrane transport namespace: biological_process def: "The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore." [GOC:isa_complete] comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "intracellular membrane translocation of a protein" EXACT [] synonym: "intracellular protein membrane transport" EXACT [] synonym: "intracellular protein transport across a membrane" EXACT [] is_a: GO:0006886 ! intracellular protein transport is_a: GO:0071806 ! protein transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input PR:000000001 ! protein intersection_of: occurs_in GO:0005622 ! intracellular anatomical structure intersection_of: results_in_transport_across GO:0016020 ! membrane [Term] id: GO:0065003 name: protein-containing complex assembly namespace: biological_process alt_id: GO:0006461 alt_id: GO:0034622 alt_id: GO:0043623 def: "The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex." [GOC:jl] subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir subset: goslim_pombe subset: goslim_prokaryote synonym: "cellular macromolecule complex assembly" RELATED [] synonym: "cellular protein complex assembly" EXACT [] synonym: "cellular protein-containing complex assembly" RELATED [] synonym: "chaperone activity" RELATED [] synonym: "macromolecular complex assembly" RELATED [] synonym: "macromolecule complex assembly" RELATED [] synonym: "protein complex assembly" RELATED [] synonym: "protein complex formation" RELATED [] is_a: GO:0022607 ! cellular component assembly is_a: GO:0043933 ! protein-containing complex organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0032991 ! protein-containing complex relationship: results_in_assembly_of GO:0032991 ! protein-containing complex property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22580" xsd:anyURI [Term] id: GO:0065004 name: protein-DNA complex assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex." [GOC:jl] synonym: "DNA-protein complex assembly" EXACT [GOC:mah] is_a: GO:0065003 ! protein-containing complex assembly is_a: GO:0071824 ! protein-DNA complex organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0032993 ! protein-DNA complex relationship: results_in_assembly_of GO:0032993 ! protein-DNA complex [Term] id: GO:0065007 name: biological regulation namespace: biological_process def: "Any process that modulates a measurable attribute of any biological process, quality or function." [GOC:dph, GOC:isa_complete, GOC:mah, GOC:pr, GOC:vw] subset: gocheck_do_not_annotate subset: goslim_pir synonym: "regulation" BROAD [] is_a: GO:0008150 ! biological process [Term] id: GO:0065008 name: regulation of biological quality namespace: biological_process def: "Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc." [GOC:dph, GOC:isa_complete, GOC:mah, GOC:pr, GOC:vw] subset: goslim_pir synonym: "regulation of biological attribute" EXACT [] synonym: "regulation of biological characteristic" EXACT [] is_a: GO:0065007 ! biological regulation [Term] id: GO:0065009 name: regulation of molecular function namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding." [GOC:isa_complete] subset: gocheck_do_not_annotate subset: goslim_pir subset: goslim_plant synonym: "regulation of a molecular function" EXACT [] is_a: GO:0065007 ! biological regulation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003674 ! molecular_function relationship: regulates GO:0003674 ! molecular_function [Term] id: GO:0065010 name: extracellular membrane-bounded organelle namespace: cellular_component def: "Organized structure of distinctive morphology and function, bounded by a lipid bilayer membrane and occurring outside the cell." [GOC:isa_complete] synonym: "extracellular membrane-enclosed organelle" EXACT [] is_a: GO:0043227 ! membrane-bounded organelle is_a: GO:0043230 ! extracellular organelle intersection_of: GO:0043227 ! membrane-bounded organelle intersection_of: part_of GO:0005576 ! extracellular region [Term] id: GO:0070013 name: intracellular organelle lumen namespace: cellular_component def: "An organelle lumen that is part of an intracellular organelle." [GOC:mah] is_a: GO:0043233 ! organelle lumen intersection_of: GO:0031974 ! membrane-enclosed lumen intersection_of: part_of GO:0043229 ! intracellular organelle relationship: part_of GO:0043229 ! intracellular organelle [Term] id: GO:0070050 name: neuron cellular homeostasis namespace: biological_process def: "The cellular homeostatic process that preserves a neuron in a stable, differentiated functional and structural state." [GOC:BHF, GOC:mah] synonym: "neuron maintenance" EXACT [] is_a: GO:0019725 ! cellular homeostasis intersection_of: GO:0019725 ! cellular homeostasis intersection_of: occurs_in CL:0000540 ! neuron relationship: occurs_in CL:0000540 ! neuron property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24218" xsd:anyURI [Term] id: GO:0070062 name: extracellular exosome namespace: cellular_component def: "A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm." [GOC:BHF, GOC:mah, GOC:vesicles, PMID:15908444, PMID:17641064, PMID:19442504, PMID:19498381, PMID:22418571, PMID:24009894] synonym: "exosome" EXACT [GOC:pr] synonym: "extracellular vesicular exosome" EXACT [GOC:vesicles] is_a: GO:1903561 ! extracellular vesicle relationship: part_of GO:0005615 ! extracellular space [Term] id: GO:0070091 name: glucagon secretion namespace: biological_process def: "The regulated release of glucagon from secretory granules in the A (alpha) cells of the pancreas (islets of Langerhans)." [GOC:BHF, GOC:rl] is_a: GO:0030072 ! peptide hormone secretion intersection_of: GO:0046903 ! secretion intersection_of: has_primary_input CHEBI:5391 ! glucagon relationship: has_primary_input CHEBI:5391 ! glucagon [Term] id: GO:0070092 name: regulation of glucagon secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of glucagon." [GOC:BHF, GOC:mah] is_a: GO:0090276 ! regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0070091 ! glucagon secretion relationship: regulates GO:0070091 ! glucagon secretion [Term] id: GO:0070093 name: negative regulation of glucagon secretion namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of glucagon." [GOC:BHF, GOC:mah] synonym: "down regulation of glucagon secretion" EXACT [] synonym: "down-regulation of glucagon secretion" EXACT [] synonym: "downregulation of glucagon secretion" EXACT [] synonym: "inhibition of glucagon secretion" NARROW [] is_a: GO:0070092 ! regulation of glucagon secretion is_a: GO:0090278 ! negative regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0070091 ! glucagon secretion relationship: negatively_regulates GO:0070091 ! glucagon secretion [Term] id: GO:0070094 name: positive regulation of glucagon secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of glucagon." [GOC:BHF, GOC:mah] synonym: "activation of glucagon secretion" NARROW [] synonym: "stimulation of glucagon secretion" NARROW [] synonym: "up regulation of glucagon secretion" EXACT [] synonym: "up-regulation of glucagon secretion" EXACT [] synonym: "upregulation of glucagon secretion" EXACT [] is_a: GO:0070092 ! regulation of glucagon secretion is_a: GO:0090277 ! positive regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0070091 ! glucagon secretion relationship: positively_regulates GO:0070091 ! glucagon secretion [Term] id: GO:0070161 name: anchoring junction namespace: cellular_component def: "A cell junction that mechanically attaches a cell (and its cytoskeleton) to neighboring cells or to the extracellular matrix." [ISBN:0815332181] synonym: "anchoring cell junction" EXACT [GOC:mah] is_a: GO:0030054 ! cell junction [Term] id: GO:0070192 name: chromosome organization involved in meiotic cell cycle namespace: biological_process def: "A process of chromosome organization that is involved in a meiotic cell cycle." [GOC:mah] synonym: "chromosome organisation involved in meiosis" EXACT [GOC:mah] synonym: "meiotic chromosome organization" EXACT [GOC:mah] is_a: GO:0051276 ! chromosome organization is_a: GO:1903046 ! meiotic cell cycle process intersection_of: GO:0051276 ! chromosome organization intersection_of: part_of GO:0051321 ! meiotic cell cycle [Term] id: GO:0070199 name: establishment of protein localization to chromosome namespace: biological_process def: "The directed movement of a protein to a specific location on a chromosome." [GOC:BHF, GOC:mah] synonym: "establishment of protein localisation to chromosome" EXACT [GOC:mah] is_a: GO:0072594 ! establishment of protein localization to organelle intersection_of: GO:0045184 ! establishment of protein localization intersection_of: has_target_end_location GO:0005694 ! chromosome relationship: has_target_end_location GO:0005694 ! chromosome [Term] id: GO:0070201 name: regulation of establishment of protein localization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location." [GOC:BHF, GOC:mah] synonym: "regulation of establishment of protein localisation" EXACT [GOC:mah] is_a: GO:0032880 ! regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0045184 ! establishment of protein localization relationship: regulates GO:0045184 ! establishment of protein localization [Term] id: GO:0070202 name: regulation of establishment of protein localization to chromosome namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location on a chromosome." [GOC:BHF, GOC:mah] synonym: "regulation of establishment of protein localisation to chromosome" EXACT [GOC:mah] is_a: GO:0070201 ! regulation of establishment of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0070199 ! establishment of protein localization to chromosome relationship: regulates GO:0070199 ! establishment of protein localization to chromosome [Term] id: GO:0070227 name: lymphocyte apoptotic process namespace: biological_process def: "Any apoptotic process in a lymphocyte, a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin." [CL:0000542, GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] comment: Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542). synonym: "lymphocyte apoptosis" NARROW [] is_a: GO:0071887 ! leukocyte apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000542 ! lymphocyte relationship: occurs_in CL:0000542 ! lymphocyte [Term] id: GO:0070228 name: regulation of lymphocyte apoptotic process namespace: biological_process def: "Any process that modulates the occurrence or rate of lymphocyte death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] comment: Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542). synonym: "regulation of lymphocyte apoptosis" NARROW [] is_a: GO:2000106 ! regulation of leukocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0070227 ! lymphocyte apoptotic process relationship: regulates GO:0070227 ! lymphocyte apoptotic process [Term] id: GO:0070229 name: negative regulation of lymphocyte apoptotic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] comment: Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542). synonym: "down regulation of lymphocyte apoptosis" EXACT [GOC:add] synonym: "down-regulation of lymphocyte apoptosis" EXACT [GOC:add] synonym: "downregulation of lymphocyte apoptosis" EXACT [GOC:add] synonym: "inhibition of lymphocyte apoptosis" NARROW [GOC:add] synonym: "negative regulation of lymphocyte apoptosis" NARROW [] is_a: GO:0070228 ! regulation of lymphocyte apoptotic process is_a: GO:2000107 ! negative regulation of leukocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0070227 ! lymphocyte apoptotic process relationship: negatively_regulates GO:0070227 ! lymphocyte apoptotic process [Term] id: GO:0070230 name: positive regulation of lymphocyte apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of lymphocyte death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] comment: Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542). synonym: "activation of lymphocyte apoptosis" NARROW [GOC:add] synonym: "positive regulation of lymphocyte apoptosis" NARROW [] synonym: "stimulation of lymphocyte apoptosis" NARROW [GOC:add] synonym: "up regulation of lymphocyte apoptosis" EXACT [GOC:add] synonym: "up-regulation of lymphocyte apoptosis" EXACT [GOC:add] synonym: "upregulation of lymphocyte apoptosis" EXACT [GOC:add] is_a: GO:0070228 ! regulation of lymphocyte apoptotic process is_a: GO:2000108 ! positive regulation of leukocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0070227 ! lymphocyte apoptotic process relationship: positively_regulates GO:0070227 ! lymphocyte apoptotic process [Term] id: GO:0070231 name: T cell apoptotic process namespace: biological_process def: "Any apoptotic process in a T cell, a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex." [CL:0000084, GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] synonym: "programmed cell death of T cells by apoptosis" EXACT [GOC:add] synonym: "T cell apoptosis" NARROW [] synonym: "T lymphocyte apoptosis" EXACT [GOC:add] synonym: "T-cell apoptosis" EXACT [GOC:add] synonym: "T-lymphocyte apoptosis" EXACT [GOC:add] is_a: GO:0070227 ! lymphocyte apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000084 ! T cell relationship: occurs_in CL:0000084 ! T cell [Term] id: GO:0070232 name: regulation of T cell apoptotic process namespace: biological_process def: "Any process that modulates the occurrence or rate of T cell death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] synonym: "regulation of programmed cell death of T cells by apoptosis" EXACT [GOC:add] synonym: "regulation of T cell apoptosis" NARROW [] synonym: "regulation of T lymphocyte apoptosis" EXACT [GOC:add] synonym: "regulation of T-cell apoptosis" EXACT [GOC:add] synonym: "regulation of T-lymphocyte apoptosis" EXACT [GOC:add] is_a: GO:0070228 ! regulation of lymphocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0070231 ! T cell apoptotic process relationship: regulates GO:0070231 ! T cell apoptotic process [Term] id: GO:0070233 name: negative regulation of T cell apoptotic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of T cell death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] synonym: "down regulation of T cell apoptosis" EXACT [GOC:add] synonym: "down-regulation of T cell apoptosis" EXACT [GOC:add] synonym: "downregulation of T cell apoptosis" EXACT [GOC:add] synonym: "inhibition of T cell apoptosis" NARROW [GOC:add] synonym: "negative regulation of programmed cell death of T cells by apoptosis" EXACT [GOC:add] synonym: "negative regulation of T cell apoptosis" NARROW [] synonym: "negative regulation of T lymphocyte apoptosis" EXACT [GOC:add] synonym: "negative regulation of T-cell apoptosis" EXACT [GOC:add] synonym: "negative regulation of T-lymphocyte apoptosis" EXACT [GOC:add] is_a: GO:0070229 ! negative regulation of lymphocyte apoptotic process is_a: GO:0070232 ! regulation of T cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0070231 ! T cell apoptotic process relationship: negatively_regulates GO:0070231 ! T cell apoptotic process [Term] id: GO:0070234 name: positive regulation of T cell apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of T cell death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] synonym: "activation of T cell apoptosis" NARROW [GOC:add] synonym: "positive regulation of programmed cell death of T cells by apoptosis" EXACT [GOC:add] synonym: "positive regulation of T cell apoptosis" NARROW [] synonym: "positive regulation of T lymphocyte apoptosis" EXACT [GOC:add] synonym: "positive regulation of T-cell apoptosis" EXACT [GOC:add] synonym: "positive regulation of T-lymphocyte apoptosis" EXACT [GOC:add] synonym: "stimulation of T cell apoptosis" NARROW [GOC:add] synonym: "up regulation of T cell apoptosis" EXACT [GOC:add] synonym: "up-regulation of T cell apoptosis" EXACT [GOC:add] synonym: "upregulation of T cell apoptosis" EXACT [GOC:add] is_a: GO:0070230 ! positive regulation of lymphocyte apoptotic process is_a: GO:0070232 ! regulation of T cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0070231 ! T cell apoptotic process relationship: positively_regulates GO:0070231 ! T cell apoptotic process [Term] id: GO:0070253 name: somatostatin secretion namespace: biological_process def: "The regulated release of somatostatin from secretory granules in the D cells of the pancreas." [GOC:mah] is_a: GO:0030072 ! peptide hormone secretion intersection_of: GO:0046903 ! secretion intersection_of: has_primary_input CHEBI:64628 ! somatostatin relationship: has_primary_input CHEBI:64628 ! somatostatin [Term] id: GO:0070254 name: mucus secretion namespace: biological_process def: "The regulated release of mucus by the mucosa. Mucus is a viscous slimy secretion consisting of mucins and various inorganic salts dissolved in water, with suspended epithelial cells and leukocytes. The mucosa, or mucous membrane, is the membrane covered with epithelium that lines the tubular organs of the body. Mucins are carbohydrate-rich glycoproteins that have a lubricating and protective function." [GOC:add, ISBN:068340007X, ISBN:0721662544] synonym: "mucus production" EXACT [GOC:add] is_a: GO:0007589 ! body fluid secretion is_a: GO:0032941 ! secretion by tissue intersection_of: GO:0046903 ! secretion intersection_of: has_primary_input UBERON:0000912 ! mucus relationship: has_primary_input UBERON:0000912 ! mucus [Term] id: GO:0070255 name: regulation of mucus secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of mucus from a cell or a tissue." [GOC:add] synonym: "regulation of mucus production" EXACT [GOC:add] is_a: GO:0050878 ! regulation of body fluid levels is_a: GO:0051046 ! regulation of secretion is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0070254 ! mucus secretion relationship: regulates GO:0070254 ! mucus secretion [Term] id: GO:0070256 name: negative regulation of mucus secretion namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of mucus from a cell or a tissue." [GOC:add] synonym: "negative regulation of mucus production" EXACT [GOC:add] is_a: GO:0051048 ! negative regulation of secretion is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:0070255 ! regulation of mucus secretion intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0070254 ! mucus secretion relationship: negatively_regulates GO:0070254 ! mucus secretion [Term] id: GO:0070257 name: positive regulation of mucus secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of mucus from a cell or a tissue." [GOC:add] synonym: "positive regulation of mucus production" EXACT [GOC:add] is_a: GO:0051047 ! positive regulation of secretion is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:0070255 ! regulation of mucus secretion intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0070254 ! mucus secretion relationship: positively_regulates GO:0070254 ! mucus secretion [Term] id: GO:0070285 name: pigment cell development namespace: biological_process def: "The process whose specific outcome is the progression of a pigment cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a pigment cell fate." [GOC:cvs] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000147 ! pigment cell relationship: part_of GO:0050931 ! pigment cell differentiation relationship: results_in_development_of CL:0000147 ! pigment cell [Term] id: GO:0070341 name: fat cell proliferation namespace: biological_process def: "The multiplication or reproduction of fat cells by cell division, resulting in the expansion of their population. A fat cell is an animal connective tissue cell specialized for the synthesis and storage of fat." [GOC:mah, GOC:sl] synonym: "adipocyte proliferation" EXACT [GOC:sl] synonym: "adipose cell proliferation" EXACT [GOC:sl] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000136 ! adipocyte relationship: acts_on_population_of CL:0000136 ! adipocyte [Term] id: GO:0070344 name: regulation of fat cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of fat cell proliferation." [GOC:mah, GOC:sl] synonym: "regulation of adipocyte proliferation" EXACT [GOC:sl] synonym: "regulation of adipose cell proliferation" EXACT [GOC:sl] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0070341 ! fat cell proliferation relationship: regulates GO:0070341 ! fat cell proliferation [Term] id: GO:0070345 name: negative regulation of fat cell proliferation namespace: biological_process def: "Any process that stops or decreases the rate or extent of fat cell proliferation." [GOC:mah, GOC:sl] synonym: "down regulation of fat cell proliferation" EXACT [GOC:mah] synonym: "down-regulation of fat cell proliferation" EXACT [GOC:mah] synonym: "downregulation of fat cell proliferation" EXACT [GOC:mah] synonym: "inhibition of fat cell proliferation" NARROW [GOC:mah] synonym: "negative regulation of adipocyte proliferation" EXACT [GOC:sl] synonym: "negative regulation of adipose cell proliferation" EXACT [GOC:sl] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0070344 ! regulation of fat cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0070341 ! fat cell proliferation relationship: negatively_regulates GO:0070341 ! fat cell proliferation [Term] id: GO:0070346 name: positive regulation of fat cell proliferation namespace: biological_process def: "Any process that activates or increases the rate or extent of fat cell proliferation." [GOC:mah, GOC:sl] synonym: "activation of fat cell proliferation" NARROW [GOC:mah] synonym: "positive regulation of adipocyte proliferation" EXACT [GOC:sl] synonym: "positive regulation of adipose cell proliferation" EXACT [GOC:sl] synonym: "stimulation of fat cell proliferation" NARROW [GOC:mah] synonym: "up regulation of fat cell proliferation" EXACT [GOC:mah] synonym: "up-regulation of fat cell proliferation" EXACT [GOC:mah] synonym: "upregulation of fat cell proliferation" EXACT [GOC:mah] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0070344 ! regulation of fat cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0070341 ! fat cell proliferation relationship: positively_regulates GO:0070341 ! fat cell proliferation [Term] id: GO:0070365 name: hepatocyte differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized features of a hepatocyte. A hepatocyte is specialized epithelial cell that is organized into interconnected plates called lobules, and is the main structural component of the liver." [CL:0000182, PMID:7588884] synonym: "liver cell differentiation" EXACT [GOC:mah] is_a: GO:0030855 ! epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000182 ! hepatocyte relationship: part_of GO:0001889 ! liver development relationship: results_in_acquisition_of_features_of CL:0000182 ! hepatocyte [Term] id: GO:0070366 name: regulation of hepatocyte differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of hepatocyte differentiation." [GOC:mah, GOC:sl] synonym: "regulation of liver cell differentiation" EXACT [GOC:sl] is_a: GO:0030856 ! regulation of epithelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0070365 ! hepatocyte differentiation relationship: regulates GO:0070365 ! hepatocyte differentiation [Term] id: GO:0070367 name: negative regulation of hepatocyte differentiation namespace: biological_process def: "Any process that stops or decreases the rate or extent of hepatocyte differentiation." [GOC:mah, GOC:sl] synonym: "down regulation of hepatocyte differentiation" EXACT [GOC:mah] synonym: "down-regulation of hepatocyte differentiation" EXACT [GOC:mah] synonym: "downregulation of hepatocyte differentiation" EXACT [GOC:mah] synonym: "inhibition of hepatocyte differentiation" NARROW [GOC:mah] synonym: "negative regulation of liver cell differentiation" EXACT [GOC:sl] is_a: GO:0030857 ! negative regulation of epithelial cell differentiation is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:0070366 ! regulation of hepatocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0070365 ! hepatocyte differentiation relationship: negatively_regulates GO:0070365 ! hepatocyte differentiation [Term] id: GO:0070368 name: positive regulation of hepatocyte differentiation namespace: biological_process def: "Any process that activates or increases the rate or extent of hepatocyte differentiation." [GOC:mah, GOC:sl] synonym: "activation of hepatocyte differentiation" NARROW [GOC:mah] synonym: "positive regulation of liver cell differentiation" EXACT [GOC:sl] synonym: "stimulation of hepatocyte differentiation" NARROW [GOC:mah] synonym: "up regulation of hepatocyte differentiation" EXACT [GOC:mah] synonym: "up-regulation of hepatocyte differentiation" EXACT [GOC:mah] synonym: "upregulation of hepatocyte differentiation" EXACT [GOC:mah] is_a: GO:0030858 ! positive regulation of epithelial cell differentiation is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:0070366 ! regulation of hepatocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0070365 ! hepatocyte differentiation relationship: positively_regulates GO:0070365 ! hepatocyte differentiation [Term] id: GO:0070382 name: exocytic vesicle namespace: cellular_component def: "A transport vesicle that mediates transport from an intracellular compartment to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis." [GOC:kad, GOC:mah] synonym: "exocytic constitutive secretory pathway transport vesicle" EXACT [] synonym: "exocytotic vesicle" EXACT [GOC:kad] is_a: GO:0030133 ! transport vesicle is_a: GO:0099503 ! secretory vesicle intersection_of: GO:0030133 ! transport vesicle intersection_of: capable_of GO:0099500 ! vesicle fusion to plasma membrane [Term] id: GO:0070482 name: response to oxygen levels namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen." [GOC:BHF, GOC:mah] is_a: GO:0009628 ! response to abiotic stimulus [Term] id: GO:0070483 name: detection of hypoxia namespace: biological_process def: "The series of events in which a stimulus indicating lowered oxygen tension is received by a cell and converted into a molecular signal. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level." [GOC:BHF, GOC:mah] synonym: "detection of reduced oxygen levels" EXACT [GOC:vk] is_a: GO:0001666 ! response to hypoxia is_a: GO:0003032 ! detection of oxygen [Term] id: GO:0070507 name: regulation of microtubule cytoskeleton organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins." [GOC:mah] synonym: "regulation of microtubule cytoskeleton organisation" EXACT [GOC:mah] synonym: "regulation of microtubule dynamics" EXACT [GOC:dph, GOC:tb] is_a: GO:0032886 ! regulation of microtubule-based process is_a: GO:0051493 ! regulation of cytoskeleton organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0000226 ! microtubule cytoskeleton organization relationship: regulates GO:0000226 ! microtubule cytoskeleton organization [Term] id: GO:0070633 name: transepithelial transport namespace: biological_process def: "The directed movement of a substance from one side of an epithelium to the other." [GOC:mah, GOC:yaf, ISBN:0716731363] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: results_in_transport_across UBERON:0000483 ! epithelium relationship: results_in_transport_across UBERON:0000483 ! epithelium created_by: mah creation_date: 2009-05-06T03:31:02Z [Term] id: GO:0070634 name: transepithelial ammonium transport namespace: biological_process def: "The directed movement of ammonium ions from one side of an epithelium to the other." [GOC:mah, GOC:yaf] is_a: GO:0070633 ! transepithelial transport is_a: GO:0071705 ! nitrogen compound transport intersection_of: GO:0070633 ! transepithelial transport intersection_of: has_primary_input CHEBI:28938 ! ammonium relationship: has_primary_input CHEBI:28938 ! ammonium created_by: mah creation_date: 2009-05-06T03:34:43Z [Term] id: GO:0070661 name: leukocyte proliferation namespace: biological_process def: "The expansion of a leukocyte population by cell division." [GOC:add] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000738 ! leukocyte relationship: acts_on_population_of CL:0000738 ! leukocyte relationship: in_taxon NCBITaxon:7742 {all_only="true"} ! Vertebrata relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata created_by: mah creation_date: 2009-05-28T05:25:28Z [Term] id: GO:0070663 name: regulation of leukocyte proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of leukocyte proliferation." [GOC:add, GOC:mah] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0070661 ! leukocyte proliferation relationship: regulates GO:0070661 ! leukocyte proliferation created_by: mah creation_date: 2009-05-28T05:30:39Z [Term] id: GO:0070664 name: negative regulation of leukocyte proliferation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte proliferation." [GOC:add, GOC:mah] synonym: "down regulation of leukocyte proliferation" EXACT [GOC:mah] synonym: "down-regulation of leukocyte proliferation" EXACT [GOC:mah] synonym: "downregulation of leukocyte proliferation" EXACT [GOC:mah] synonym: "inhibition of leukocyte proliferation" NARROW [GOC:mah] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0070663 ! regulation of leukocyte proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0070661 ! leukocyte proliferation relationship: negatively_regulates GO:0070661 ! leukocyte proliferation created_by: mah creation_date: 2009-05-28T05:34:50Z [Term] id: GO:0070665 name: positive regulation of leukocyte proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of leukocyte proliferation." [GOC:add, GOC:mah] synonym: "activation of leukocyte proliferation" NARROW [GOC:mah] synonym: "stimulation of leukocyte proliferation" NARROW [GOC:mah] synonym: "up regulation of leukocyte proliferation" EXACT [GOC:mah] synonym: "up-regulation of leukocyte proliferation" EXACT [GOC:mah] synonym: "upregulation of leukocyte proliferation" EXACT [GOC:mah] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0070663 ! regulation of leukocyte proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0070661 ! leukocyte proliferation relationship: positively_regulates GO:0070661 ! leukocyte proliferation created_by: mah creation_date: 2009-05-28T05:36:46Z [Term] id: GO:0070727 name: cellular macromolecule localization namespace: biological_process def: "Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell." [GOC:mah] synonym: "cellular macromolecule localisation" EXACT [GOC:mah] is_a: GO:0033036 ! macromolecule localization is_a: GO:0051641 ! cellular localization created_by: mah creation_date: 2009-06-16T04:08:29Z [Term] id: GO:0070831 name: basement membrane assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form a basement membrane, a part of the extracellular region that consists of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue." [GOC:mah] comment: Note that this term has no relationship to 'membrane assembly ; GO:0071709' because the basement membrane is not a lipid bilayer. is_a: GO:0071711 ! basement membrane organization is_a: GO:0085029 ! extracellular matrix assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0005604 ! basement membrane relationship: results_in_assembly_of GO:0005604 ! basement membrane created_by: mah creation_date: 2009-07-23T05:01:51Z [Term] id: GO:0070857 name: regulation of bile acid biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids." [GOC:BHF, GOC:mah] synonym: "regulation of bile acid anabolism" EXACT [GOC:mah] synonym: "regulation of bile acid biosynthesis" EXACT [GOC:mah] synonym: "regulation of bile acid formation" EXACT [GOC:mah] synonym: "regulation of bile acid synthesis" EXACT [GOC:mah] is_a: GO:0010565 ! regulation of cellular ketone metabolic process is_a: GO:0031326 ! regulation of cellular biosynthetic process is_a: GO:0050810 ! regulation of steroid biosynthetic process is_a: GO:1904251 ! regulation of bile acid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006699 ! bile acid biosynthetic process relationship: regulates GO:0006699 ! bile acid biosynthetic process created_by: mah creation_date: 2009-08-14T03:09:02Z [Term] id: GO:0070858 name: negative regulation of bile acid biosynthetic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids." [GOC:BHF, GOC:mah] synonym: "down regulation of bile acid biosynthetic process" EXACT [GOC:mah] synonym: "down-regulation of bile acid biosynthetic process" EXACT [GOC:mah] synonym: "downregulation of bile acid biosynthetic process" EXACT [GOC:mah] synonym: "inhibition of bile acid biosynthetic process" NARROW [GOC:mah] synonym: "negative regulation of bile acid anabolism" EXACT [GOC:mah] synonym: "negative regulation of bile acid biosynthesis" EXACT [GOC:mah] synonym: "negative regulation of bile acid formation" EXACT [GOC:mah] synonym: "negative regulation of bile acid synthesis" EXACT [GOC:mah] is_a: GO:0010894 ! negative regulation of steroid biosynthetic process is_a: GO:0031327 ! negative regulation of cellular biosynthetic process is_a: GO:0070857 ! regulation of bile acid biosynthetic process is_a: GO:1904252 ! negative regulation of bile acid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006699 ! bile acid biosynthetic process relationship: negatively_regulates GO:0006699 ! bile acid biosynthetic process created_by: mah creation_date: 2009-08-14T03:16:40Z [Term] id: GO:0070859 name: positive regulation of bile acid biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids." [GOC:BHF, GOC:mah] synonym: "activation of bile acid biosynthetic process" NARROW [GOC:mah] synonym: "positive regulation of bile acid anabolism" EXACT [GOC:mah] synonym: "positive regulation of bile acid biosynthesis" EXACT [GOC:mah] synonym: "positive regulation of bile acid formation" EXACT [GOC:mah] synonym: "positive regulation of bile acid synthesis" EXACT [GOC:mah] synonym: "stimulation of bile acid biosynthetic process" NARROW [GOC:mah] synonym: "up regulation of bile acid biosynthetic process" EXACT [GOC:mah] synonym: "up-regulation of bile acid biosynthetic process" EXACT [GOC:mah] synonym: "upregulation of bile acid biosynthetic process" EXACT [GOC:mah] is_a: GO:0010893 ! positive regulation of steroid biosynthetic process is_a: GO:0031328 ! positive regulation of cellular biosynthetic process is_a: GO:0070857 ! regulation of bile acid biosynthetic process is_a: GO:1904253 ! positive regulation of bile acid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006699 ! bile acid biosynthetic process relationship: positively_regulates GO:0006699 ! bile acid biosynthetic process created_by: mah creation_date: 2009-08-14T03:22:58Z [Term] id: GO:0070873 name: regulation of glycogen metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glycogen." [GOC:mah] synonym: "regulation of glycogen metabolism" EXACT [GOC:mah] is_a: GO:0032881 ! regulation of polysaccharide metabolic process is_a: GO:0043467 ! regulation of generation of precursor metabolites and energy intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0005977 ! glycogen metabolic process relationship: regulates GO:0005977 ! glycogen metabolic process created_by: mah creation_date: 2009-08-20T02:44:53Z [Term] id: GO:0070874 name: negative regulation of glycogen metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glycogen." [GOC:mah] synonym: "negative regulation of glycogen metabolism" EXACT [GOC:mah] is_a: GO:0010605 ! negative regulation of macromolecule metabolic process is_a: GO:0031324 ! negative regulation of cellular metabolic process is_a: GO:0045912 ! negative regulation of carbohydrate metabolic process is_a: GO:0070873 ! regulation of glycogen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0005977 ! glycogen metabolic process relationship: negatively_regulates GO:0005977 ! glycogen metabolic process created_by: mah creation_date: 2009-08-20T02:50:41Z [Term] id: GO:0070875 name: positive regulation of glycogen metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glycogen." [GOC:mah] synonym: "positive regulation of glycogen metabolism" EXACT [GOC:mah] is_a: GO:0010604 ! positive regulation of macromolecule metabolic process is_a: GO:0010907 ! positive regulation of glucose metabolic process is_a: GO:0031325 ! positive regulation of cellular metabolic process is_a: GO:0070873 ! regulation of glycogen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0005977 ! glycogen metabolic process relationship: positively_regulates GO:0005977 ! glycogen metabolic process created_by: mah creation_date: 2009-08-20T02:53:55Z [Term] id: GO:0070925 name: organelle assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane." [GOC:mah] subset: goslim_yeast is_a: GO:0006996 ! organelle organization is_a: GO:0022607 ! cellular component assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0043226 ! organelle relationship: results_in_assembly_of GO:0043226 ! organelle created_by: mah creation_date: 2009-09-15T03:00:51Z [Term] id: GO:0070977 name: bone maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for bone to attain its fully functional state." [GOC:dph, GOC:mah] is_a: GO:0048799 ! animal organ maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of UBERON:0001474 ! bone element relationship: part_of GO:0060348 ! bone development relationship: results_in_maturation_of UBERON:0001474 ! bone element created_by: mah creation_date: 2009-10-05T04:35:31Z [Term] id: GO:0071168 name: protein localization to chromatin namespace: biological_process def: "Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into chromatin." [GOC:mah] synonym: "protein localisation to chromatin" EXACT [GOC:mah] is_a: GO:0034502 ! protein localization to chromosome intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0000785 ! chromatin relationship: has_target_end_location GO:0000785 ! chromatin created_by: mah creation_date: 2009-11-20T11:51:20Z [Term] id: GO:0071169 name: establishment of protein localization to chromatin namespace: biological_process def: "The directed movement of a protein to a part of a chromosome that is organized into chromatin." [GOC:mah] synonym: "establishment of protein localisation to chromatin" EXACT [GOC:mah] is_a: GO:0070199 ! establishment of protein localization to chromosome intersection_of: GO:0045184 ! establishment of protein localization intersection_of: has_target_end_location GO:0000785 ! chromatin relationship: has_target_end_location GO:0000785 ! chromatin created_by: mah creation_date: 2009-11-20T11:52:43Z [Term] id: GO:0071425 name: hematopoietic stem cell proliferation namespace: biological_process def: "The expansion of a hematopoietic stem cell population by cell division. A hematopoietic stem cell is a stem cell from which all cells of the lymphoid and myeloid lineages develop." [CL:0000037, GOC:add, GOC:BHF, GOC:mah, GOC:rl] synonym: "hemopoietic stem cell proliferation" EXACT [] is_a: GO:0072089 ! stem cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000037 ! hematopoietic stem cell relationship: acts_on_population_of CL:0000037 ! hematopoietic stem cell relationship: part_of GO:0030097 ! hemopoiesis created_by: mah creation_date: 2009-12-16T10:22:52Z [Term] id: GO:0071626 name: mastication namespace: biological_process def: "The process of biting and mashing food with the teeth prior to swallowing." [GOC:gvg] synonym: "chewing" EXACT [GOC:mah] is_a: GO:0022600 ! digestive system process created_by: mah creation_date: 2010-02-10T11:19:48Z [Term] id: GO:0071674 name: mononuclear cell migration namespace: biological_process def: "The movement of a mononuclear cell within or between different tissues and organs of the body." [GOC:mah] is_a: GO:0050900 ! leukocyte migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000842 ! mononuclear cell relationship: results_in_movement_of CL:0000842 ! mononuclear cell created_by: mah creation_date: 2010-02-16T02:11:00Z [Term] id: GO:0071675 name: regulation of mononuclear cell migration namespace: biological_process def: "Any process that modulates the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body." [GOC:mah] is_a: GO:0002685 ! regulation of leukocyte migration intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0071674 ! mononuclear cell migration relationship: regulates GO:0071674 ! mononuclear cell migration created_by: mah creation_date: 2010-02-16T02:11:53Z [Term] id: GO:0071676 name: negative regulation of mononuclear cell migration namespace: biological_process def: "Any process that decreases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body." [GOC:mah] synonym: "down regulation of mononuclear cell migration" EXACT [GOC:mah] synonym: "down-regulation of mononuclear cell migration" EXACT [GOC:mah] synonym: "downregulation of mononuclear cell migration" EXACT [GOC:mah] synonym: "inhibition of mononuclear cell migration" NARROW [GOC:mah] is_a: GO:0002686 ! negative regulation of leukocyte migration is_a: GO:0071675 ! regulation of mononuclear cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0071674 ! mononuclear cell migration relationship: negatively_regulates GO:0071674 ! mononuclear cell migration created_by: mah creation_date: 2010-02-16T02:13:55Z [Term] id: GO:0071677 name: positive regulation of mononuclear cell migration namespace: biological_process def: "Any process that increases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body." [GOC:mah] synonym: "activation of mononuclear cell migration" NARROW [GOC:mah] synonym: "stimulation of mononuclear cell migration" NARROW [GOC:mah] synonym: "up regulation of mononuclear cell migration" EXACT [GOC:mah] synonym: "up-regulation of mononuclear cell migration" EXACT [GOC:mah] synonym: "upregulation of mononuclear cell migration" EXACT [GOC:mah] is_a: GO:0002687 ! positive regulation of leukocyte migration is_a: GO:0071675 ! regulation of mononuclear cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0071674 ! mononuclear cell migration relationship: positively_regulates GO:0071674 ! mononuclear cell migration created_by: mah creation_date: 2010-02-16T02:15:29Z [Term] id: GO:0071692 name: protein localization to extracellular region namespace: biological_process def: "Any process in which a protein is transported from one specific location in the extracellular region to another, or maintained in a specific extracellular location." [GOC:mah] synonym: "protein localisation in extracellular region" EXACT [GOC:mah] synonym: "protein localization in extracellular region" EXACT [] is_a: GO:0008104 ! protein localization intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0005576 ! extracellular region relationship: has_target_end_location GO:0005576 ! extracellular region created_by: mah creation_date: 2010-02-25T04:00:13Z [Term] id: GO:0071695 name: anatomical structure maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure to attain its fully functional state." [GOC:mah] is_a: GO:0021700 ! developmental maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of UBERON:0000061 ! anatomical structure relationship: part_of GO:0048856 ! anatomical structure development relationship: results_in_maturation_of UBERON:0000061 ! anatomical structure created_by: mah creation_date: 2010-03-02T11:43:38Z [Term] id: GO:0071696 name: ectodermal placode development namespace: biological_process def: "The progression of an ectodermal placode over time from its initial formation until its mature state. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm." [GOC:mah] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005085 ! ectodermal placode relationship: results_in_development_of UBERON:0005085 ! ectodermal placode created_by: mah creation_date: 2010-03-02T11:48:01Z [Term] id: GO:0071697 name: ectodermal placode morphogenesis namespace: biological_process def: "The process in which the anatomical structures of an ectodermal placode are generated and organized. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm." [GOC:mah] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0005085 ! ectodermal placode relationship: part_of GO:0071696 ! ectodermal placode development relationship: results_in_morphogenesis_of UBERON:0005085 ! ectodermal placode created_by: mah creation_date: 2010-03-02T11:49:51Z [Term] id: GO:0071702 name: organic substance transport namespace: biological_process def: "The directed movement of organic substances into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. An organic substance is a molecular entity that contains carbon." [GOC:mah] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:50860 ! organic molecular entity relationship: has_primary_input CHEBI:50860 ! organic molecular entity created_by: mah creation_date: 2010-03-08T02:15:14Z [Term] id: GO:0071704 name: organic substance metabolic process namespace: biological_process def: "The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon." [GOC:mah] subset: gocheck_do_not_annotate synonym: "organic molecular entity metabolic process" EXACT [] synonym: "organic molecular entity metabolism" EXACT [] synonym: "organic substance metabolism" EXACT [] is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:50860 ! organic molecular entity relationship: has_primary_input_or_output CHEBI:50860 ! organic molecular entity property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI created_by: mah creation_date: 2010-03-08T03:32:18Z [Term] id: GO:0071705 name: nitrogen compound transport namespace: biological_process def: "The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:51143 ! nitrogen molecular entity relationship: has_primary_input CHEBI:51143 ! nitrogen molecular entity created_by: mah creation_date: 2010-03-08T03:56:28Z [Term] id: GO:0071709 name: membrane assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form a membrane." [GOC:mah] is_a: GO:0022607 ! cellular component assembly is_a: GO:0061024 ! membrane organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0016020 ! membrane relationship: part_of GO:0044091 ! membrane biogenesis relationship: results_in_assembly_of GO:0016020 ! membrane created_by: mah creation_date: 2010-03-10T11:19:17Z [Term] id: GO:0071711 name: basement membrane organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the basement membrane." [GOC:mah] comment: Note that this term has no relationship to 'membrane organization ; GO:0061024' because the basement membrane is not a lipid bilayer. synonym: "basement membrane organisation" EXACT [GOC:mah] is_a: GO:0030198 ! extracellular matrix organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0005604 ! basement membrane relationship: results_in_organization_of GO:0005604 ! basement membrane created_by: mah creation_date: 2010-03-10T11:57:10Z [Term] id: GO:0071763 name: nuclear membrane organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner or outer membrane." [GOC:mah] synonym: "nuclear membrane organisation" EXACT [GOC:mah] synonym: "nuclear membrane organization and biogenesis" RELATED [GOC:mah] is_a: GO:0061024 ! membrane organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0031965 ! nuclear membrane relationship: part_of GO:0006998 ! nuclear envelope organization relationship: results_in_organization_of GO:0031965 ! nuclear membrane created_by: mah creation_date: 2010-03-29T03:59:35Z [Term] id: GO:0071764 name: nuclear outer membrane organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear outer membrane." [GOC:mah] synonym: "nuclear outer membrane organisation" EXACT [GOC:mah] synonym: "nuclear outer membrane organization and biogenesis" RELATED [GOC:mah] is_a: GO:0071763 ! nuclear membrane organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0005640 ! nuclear outer membrane relationship: results_in_organization_of GO:0005640 ! nuclear outer membrane created_by: mah creation_date: 2010-03-29T04:03:37Z [Term] id: GO:0071806 name: protein transmembrane transport namespace: biological_process def: "The process in which a protein is transported across a membrane." [GOC:mah, GOC:vw] comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "protein membrane transport" EXACT [] is_a: GO:0045184 ! establishment of protein localization is_a: GO:0055085 ! transmembrane transport is_a: GO:0071702 ! organic substance transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:36080 ! protein intersection_of: results_in_transport_across GO:0016020 ! membrane created_by: mah creation_date: 2010-09-03T02:54:26Z [Term] id: GO:0071824 name: protein-DNA complex organization namespace: biological_process def: "Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-DNA complex." [GOC:mah] synonym: "DNA-protein complex subunit organization" EXACT [GOC:mah] synonym: "protein-DNA complex subunit organisation" EXACT [GOC:mah] synonym: "protein-DNA complex subunit organization" EXACT [] is_a: GO:0043933 ! protein-containing complex organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0032993 ! protein-DNA complex relationship: results_in_organization_of GO:0032993 ! protein-DNA complex created_by: mah creation_date: 2010-09-08T10:03:26Z [Term] id: GO:0071826 name: protein-RNA complex organization namespace: biological_process def: "Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a ribonucleoprotein complex." [GOC:mah] synonym: "protein-RNA complex subunit organization" EXACT [GOC:mah] synonym: "ribonucleoprotein complex subunit organisation" EXACT [GOC:mah] synonym: "ribonucleoprotein complex subunit organization" EXACT [] synonym: "RNA-protein complex subunit organization" EXACT [GOC:mah] is_a: GO:0043933 ! protein-containing complex organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:1990904 ! ribonucleoprotein complex relationship: results_in_organization_of GO:1990904 ! ribonucleoprotein complex property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/25143" xsd:anyURI created_by: mah creation_date: 2010-09-08T10:10:35Z [Term] id: GO:0071840 name: cellular component organization or biogenesis namespace: biological_process alt_id: GO:0071841 def: "A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component." [GOC:mah] subset: goslim_flybase_ribbon subset: goslim_metagenomics synonym: "cellular component organisation or biogenesis" EXACT [GOC:mah] synonym: "cellular component organisation or biogenesis at cellular level" EXACT [GOC:mah] synonym: "cellular component organization or biogenesis at cellular level" EXACT [] is_a: GO:0009987 ! cellular process created_by: mah creation_date: 2010-09-10T01:39:16Z [Term] id: GO:0071867 name: response to monoamine namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan." [GOC:mah] synonym: "response to monoamine stimulus" EXACT [GOC:dos] is_a: GO:0010243 ! response to organonitrogen compound intersection_of: GO:0050896 ! response to stimulus intersection_of: has_primary_input CHEBI:63534 ! monoamine relationship: has_primary_input CHEBI:63534 ! monoamine created_by: mah creation_date: 2010-09-13T02:36:37Z [Term] id: GO:0071869 name: response to catecholamine namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution." [GOC:BHF, GOC:mah] synonym: "response to catecholamine stimulus" EXACT [GOC:dos] is_a: GO:0014070 ! response to organic cyclic compound is_a: GO:0071867 ! response to monoamine is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus intersection_of: has_primary_input CHEBI:33567 ! catecholamine relationship: has_primary_input CHEBI:33567 ! catecholamine created_by: mah creation_date: 2010-09-13T02:51:13Z [Term] id: GO:0071873 name: response to norepinephrine namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system." [GOC:BHF, GOC:mah] comment: Note that epinephrine and norepinephrine are ligands for the same receptors, and there are multiple adrenergic receptors. synonym: "response to noradrenaline stimulus" EXACT [GOC:mah] synonym: "response to norepinephrine stimulus" EXACT [GOC:dos] is_a: GO:0010033 ! response to organic substance is_a: GO:1901698 ! response to nitrogen compound intersection_of: GO:0050896 ! response to stimulus intersection_of: has_primary_input CHEBI:72587 ! (R)-noradrenaline(1+) relationship: has_primary_input CHEBI:72587 ! (R)-noradrenaline(1+) created_by: mah creation_date: 2010-09-13T03:31:53Z [Term] id: GO:0071887 name: leukocyte apoptotic process namespace: biological_process def: "Any apoptotic process in a leukocyte, an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue." [CL:0000738, GOC:BHF, GOC:mah, GOC:mtg_apoptosis] comment: Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542). synonym: "leukocyte apoptosis" NARROW [] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000738 ! leukocyte relationship: in_taxon NCBITaxon:7742 {all_only="true"} ! Vertebrata relationship: occurs_in CL:0000738 ! leukocyte relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata created_by: mah creation_date: 2010-09-14T12:44:09Z [Term] id: GO:0071897 name: DNA biosynthetic process namespace: biological_process def: "The biosynthetic process resulting in the formation of DNA." [GOC:mah] synonym: "DNA anabolism" EXACT [GOC:mah] synonym: "DNA biosynthesis" EXACT [GOC:mah] synonym: "DNA formation" EXACT [GOC:mah] synonym: "DNA synthesis" EXACT [GOC:mah] is_a: GO:0006259 ! DNA metabolic process is_a: GO:0009059 ! macromolecule biosynthetic process is_a: GO:0034654 ! nucleobase-containing compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:16991 ! deoxyribonucleic acid relationship: has_primary_output CHEBI:16991 ! deoxyribonucleic acid created_by: mah creation_date: 2010-09-15T02:14:33Z [Term] id: GO:0071944 name: cell periphery namespace: cellular_component def: "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures." [GOC:pdt] subset: goslim_flybase_ribbon is_a: GO:0110165 ! cellular anatomical entity created_by: mah creation_date: 2010-10-04T01:51:47Z [Term] id: GO:0071953 name: elastic fiber namespace: cellular_component def: "An supramolecular fiber that consists of an insoluble core of polymerized tropoelastin monomers and a surrounding mantle of microfibrils. Elastic fibers provide elasticity and recoiling to tissues and organs, and maintain structural integrity against mechanical strain." [GOC:BHF, GOC:mah, PMID:20236620] synonym: "elastic fibre" EXACT [GOC:mah] synonym: "elastin fiber" EXACT [GOC:BHF] is_a: GO:0099512 ! supramolecular fiber relationship: part_of GO:0031012 ! extracellular matrix created_by: mah creation_date: 2010-10-11T11:44:57Z [Term] id: GO:0071971 name: extracellular exosome assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form an extracellular vesicular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Exosomes are defined by their size, which generally ranges from 30 nm to 100 nm." [GOC:mah, GOC:tfm, PMID:19442504, PMID:27462458] synonym: "extracellular vesicular exosome assembly" EXACT [GOC:vesicles] is_a: GO:0016050 ! vesicle organization is_a: GO:0070925 ! organelle assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0070062 ! extracellular exosome relationship: part_of GO:0097734 ! extracellular exosome biogenesis relationship: results_in_assembly_of GO:0070062 ! extracellular exosome created_by: mah creation_date: 2010-10-18T03:44:18Z [Term] id: GO:0072001 name: renal system development namespace: biological_process def: "The process whose specific outcome is the progression of the renal system over time, from its formation to the mature structure. The renal system maintains fluid balance and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels." [GOC:mtg_kidney_jan10, GOC:yaf, http://en.wikibooks.org/wiki/Human_Physiology/The_Urinary_System] subset: gocheck_do_not_annotate synonym: "urinary system development" BROAD [GOC:yaf] synonym: "urinary tract development" BROAD [GOC:yaf, PMID:17881463] is_a: GO:0048731 ! system development intersection_of: GO:0048731 ! system development intersection_of: results_in_development_of UBERON:0001008 ! renal system relationship: results_in_development_of UBERON:0001008 ! renal system created_by: mah creation_date: 2010-01-25T10:31:00Z [Term] id: GO:0072003 name: kidney rudiment formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a kidney rudiment from unspecified parts. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10] synonym: "kidney anlage formation" RELATED [GOC:mtg_kidney_jan10] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0005095 ! kidney rudiment relationship: part_of GO:0060993 ! kidney morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0005095 ! kidney rudiment created_by: mah creation_date: 2010-01-25T11:18:58Z [Term] id: GO:0072006 name: nephron development namespace: biological_process def: "The process whose specific outcome is the progression of the nephron over time, from its formation to the mature structure. A nephron is the functional unit of the kidney." [GOC:mtg_kidney_jan10] synonym: "nephrogenesis" RELATED [GOC:rph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001285 ! nephron relationship: part_of GO:0001822 ! kidney development relationship: results_in_development_of UBERON:0001285 ! nephron created_by: mah creation_date: 2010-01-25T01:37:16Z [Term] id: GO:0072009 name: nephron epithelium development namespace: biological_process def: "The process whose specific outcome is the progression of the nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The nephron epithelium is a tissue that covers the surface of a nephron." [GOC:mtg_kidney_jan10] is_a: GO:0072073 ! kidney epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004211 ! nephron epithelium relationship: part_of GO:0072006 ! nephron development relationship: results_in_development_of UBERON:0004211 ! nephron epithelium created_by: mah creation_date: 2010-01-25T02:01:39Z [Term] id: GO:0072028 name: nephron morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the nephron are generated and organized. A nephron is the functional unit of the kidney." [GOC:mtg_kidney_jan10] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001285 ! nephron relationship: part_of GO:0060993 ! kidney morphogenesis relationship: part_of GO:0072006 ! nephron development relationship: results_in_morphogenesis_of UBERON:0001285 ! nephron created_by: mah creation_date: 2010-01-25T02:45:52Z [Term] id: GO:0072033 name: renal vesicle formation namespace: biological_process def: "The developmental process pertaining to the initial formation of the renal vesicle from condensed mesenchymal cells. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells." [GOC:mtg_kidney_jan10] synonym: "nephron epithelium formation" RELATED [GOC:mtg_kidney_jan10] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0004209 ! renal vesicle relationship: part_of GO:0072077 ! renal vesicle morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0004209 ! renal vesicle created_by: mah creation_date: 2010-01-25T02:57:03Z [Term] id: GO:0072036 name: mesenchymal to epithelial transition involved in renal vesicle formation namespace: biological_process def: "A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the renal vesicle." [GOC:mtg_kidney_jan10] is_a: GO:0035850 ! epithelial cell differentiation involved in kidney development is_a: GO:0060231 ! mesenchymal to epithelial transition intersection_of: GO:0060231 ! mesenchymal to epithelial transition intersection_of: part_of GO:0072033 ! renal vesicle formation relationship: part_of GO:0072033 ! renal vesicle formation created_by: mah creation_date: 2010-01-25T03:04:24Z [Term] id: GO:0072038 name: mesenchymal stem cell maintenance involved in nephron morphogenesis namespace: biological_process def: "The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells." [GOC:mtg_kidney_jan10] is_a: GO:0035019 ! somatic stem cell population maintenance relationship: part_of GO:0072028 ! nephron morphogenesis created_by: mah creation_date: 2010-01-25T03:08:05Z [Term] id: GO:0072039 name: regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis namespace: biological_process def: "Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] synonym: "regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis" NARROW [] synonym: "regulation of mesenchymal stem cell apoptotic process involved in nephron morphogenesis" EXACT [] is_a: GO:1902337 ! regulation of apoptotic process involved in morphogenesis is_a: GO:1904672 ! regulation of somatic stem cell population maintenance is_a: GO:2001053 ! regulation of mesenchymal cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1901145 ! mesenchymal cell apoptotic process involved in nephron morphogenesis relationship: regulates GO:0072038 ! mesenchymal stem cell maintenance involved in nephron morphogenesis relationship: regulates GO:1901145 ! mesenchymal cell apoptotic process involved in nephron morphogenesis created_by: mah creation_date: 2010-01-25T03:08:34Z [Term] id: GO:0072040 name: negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis namespace: biological_process def: "Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] synonym: "negative regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis" NARROW [] synonym: "negative regulation of mesenchymal stem cell apoptotic process involved in nephron morphogenesis" EXACT [] is_a: GO:0072039 ! regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis is_a: GO:1902338 ! negative regulation of apoptotic process involved in morphogenesis is_a: GO:1904673 ! negative regulation of somatic stem cell population maintenance is_a: GO:2001054 ! negative regulation of mesenchymal cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1901145 ! mesenchymal cell apoptotic process involved in nephron morphogenesis relationship: negatively_regulates GO:0072038 ! mesenchymal stem cell maintenance involved in nephron morphogenesis relationship: negatively_regulates GO:1901145 ! mesenchymal cell apoptotic process involved in nephron morphogenesis created_by: mah creation_date: 2010-01-25T03:09:30Z [Term] id: GO:0072041 name: positive regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis namespace: biological_process def: "Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] synonym: "positive regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis" NARROW [] synonym: "positive regulation of mesenchymal stem cell apoptotic process involved in nephron morphogenesis" EXACT [] is_a: GO:0072039 ! regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis is_a: GO:1902339 ! positive regulation of apoptotic process involved in morphogenesis is_a: GO:1904674 ! positive regulation of somatic stem cell population maintenance is_a: GO:2001055 ! positive regulation of mesenchymal cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1901145 ! mesenchymal cell apoptotic process involved in nephron morphogenesis relationship: positively_regulates GO:0072038 ! mesenchymal stem cell maintenance involved in nephron morphogenesis relationship: positively_regulates GO:1901145 ! mesenchymal cell apoptotic process involved in nephron morphogenesis created_by: mah creation_date: 2010-01-25T03:10:32Z [Term] id: GO:0072044 name: collecting duct development namespace: biological_process def: "The process whose specific outcome is the progression of a collecting duct over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. It is the final common path through which urine flows before entering the ureter and then emptying into the bladder." [GOC:mtg_kidney_jan10] is_a: GO:0035295 ! tube development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001232 ! collecting duct of renal tubule relationship: part_of GO:0001822 ! kidney development relationship: results_in_development_of UBERON:0001232 ! collecting duct of renal tubule created_by: mah creation_date: 2010-01-25T03:18:06Z [Term] id: GO:0072048 name: renal system pattern specification namespace: biological_process def: "Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate into the anatomical structures of the renal system." [GOC:mtg_kidney_jan10] subset: gocheck_do_not_annotate synonym: "renal system pattern formation" RELATED [GOC:mtg_kidney_jan10] is_a: GO:0007389 ! pattern specification process relationship: part_of GO:0072001 ! renal system development created_by: mah creation_date: 2010-01-25T03:31:51Z [Term] id: GO:0072055 name: renal cortex development namespace: biological_process def: "The process whose specific outcome is the progression of the renal cortex over time, from its formation to the mature structure. The renal cortex is the outer region of the kidney." [GOC:mtg_kidney_jan10] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001225 ! cortex of kidney relationship: part_of GO:0001822 ! kidney development relationship: results_in_development_of UBERON:0001225 ! cortex of kidney created_by: mah creation_date: 2010-01-25T04:01:12Z [Term] id: GO:0072059 name: cortical collecting duct development namespace: biological_process def: "The process whose specific outcome is the progression of the cortical collecting duct over time, from its formation to the mature structure. The cortical collecting duct is the portion of the collecting duct that resides in the renal cortex." [GOC:mtg_kidney_jan10] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004203 ! cortical collecting duct relationship: results_in_development_of UBERON:0004203 ! cortical collecting duct created_by: mah creation_date: 2010-01-25T04:07:07Z [Term] id: GO:0072071 name: kidney interstitial fibroblast differentiation namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblast of the kidney as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] synonym: "kidney interstitial cell differentiation" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0061005 ! cell differentiation involved in kidney development intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:1000692 ! kidney interstitial fibroblast relationship: results_in_acquisition_of_features_of CL:1000692 ! kidney interstitial fibroblast created_by: mah creation_date: 2010-01-25T04:34:31Z [Term] id: GO:0072073 name: kidney epithelium development namespace: biological_process def: "The process whose specific outcome is the progression of an epithelium in the kidney over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure." [GOC:mtg_kidney_jan10] is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004819 ! kidney epithelium relationship: part_of GO:0001822 ! kidney development relationship: results_in_development_of UBERON:0004819 ! kidney epithelium created_by: mah creation_date: 2010-01-25T04:37:42Z [Term] id: GO:0072074 name: kidney mesenchyme development namespace: biological_process def: "The biological process whose specific outcome is the progression of a kidney mesenchyme from an initial condition to its mature state. This process begins with the formation of kidney mesenchyme and ends with the mature structure. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney." [GOC:mtg_kidney_jan10] is_a: GO:0060485 ! mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003918 ! kidney mesenchyme relationship: part_of GO:0001822 ! kidney development relationship: results_in_development_of UBERON:0003918 ! kidney mesenchyme created_by: mah creation_date: 2010-01-25T04:39:04Z [Term] id: GO:0072075 name: metanephric mesenchyme development namespace: biological_process def: "The biological process whose specific outcome is the progression of a metanephric mesenchyme from an initial condition to its mature state. This process begins with the formation of metanephric mesenchyme and ends with the mature structure. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0072074 ! kidney mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003220 ! metanephric mesenchyme relationship: part_of GO:0001656 ! metanephros development relationship: results_in_development_of UBERON:0003220 ! metanephric mesenchyme created_by: mah creation_date: 2010-01-25T04:40:11Z [Term] id: GO:0072076 name: nephrogenic mesenchyme development namespace: biological_process def: "The biological process whose specific outcome is the progression of a nephrogenic mesenchyme from an initial condition to its mature state. This process begins with the formation of nephrogenic mesenchyme and ends with the mature structure. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron." [GOC:mtg_kidney_jan10] is_a: GO:0072074 ! kidney mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004208 ! nephrogenic mesenchyme relationship: part_of GO:0072006 ! nephron development relationship: results_in_development_of UBERON:0004208 ! nephrogenic mesenchyme created_by: mah creation_date: 2010-01-25T04:40:44Z [Term] id: GO:0072077 name: renal vesicle morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the renal vesicle are generated and organized. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells." [GOC:mtg_kidney_jan10] is_a: GO:0002009 ! morphogenesis of an epithelium intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0004209 ! renal vesicle relationship: part_of GO:0072087 ! renal vesicle development relationship: part_of GO:0072088 ! nephron epithelium morphogenesis relationship: results_in_morphogenesis_of UBERON:0004209 ! renal vesicle created_by: mah creation_date: 2010-02-01T02:21:06Z [Term] id: GO:0072078 name: nephron tubule morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a nephron tubule are generated and organized. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney." [GOC:mtg_kidney_jan10] is_a: GO:0061333 ! renal tubule morphogenesis is_a: GO:0072088 ! nephron epithelium morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001231 ! nephron tubule relationship: part_of GO:0072080 ! nephron tubule development relationship: results_in_morphogenesis_of UBERON:0001231 ! nephron tubule created_by: mah creation_date: 2010-02-01T02:25:14Z [Term] id: GO:0072079 name: nephron tubule formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a nephron tubule from unspecified parts. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney." [GOC:mtg_kidney_jan10] is_a: GO:0001838 ! embryonic epithelial tube formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0001231 ! nephron tubule relationship: part_of GO:0072078 ! nephron tubule morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0001231 ! nephron tubule created_by: mah creation_date: 2010-02-01T02:29:26Z [Term] id: GO:0072080 name: nephron tubule development namespace: biological_process def: "The progression of a nephron tubule over time, from its initial formation to the mature structure. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney." [GOC:mtg_kidney_jan10] is_a: GO:0061326 ! renal tubule development is_a: GO:0072009 ! nephron epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001231 ! nephron tubule relationship: results_in_development_of UBERON:0001231 ! nephron tubule created_by: mah creation_date: 2010-02-01T02:32:12Z [Term] id: GO:0072087 name: renal vesicle development namespace: biological_process def: "The process whose specific outcome is the progression of the renal vesicle over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells." [GOC:mtg_kidney_jan10] is_a: GO:0072073 ! kidney epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004209 ! renal vesicle relationship: part_of GO:0072009 ! nephron epithelium development relationship: results_in_development_of UBERON:0004209 ! renal vesicle created_by: mah creation_date: 2010-02-08T01:18:31Z [Term] id: GO:0072088 name: nephron epithelium morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the nephron epithelium are generated and organized. The nephron epithelium is a tissue that covers the surface of a nephron." [GOC:mtg_kidney_jan10] is_a: GO:0002009 ! morphogenesis of an epithelium intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0004211 ! nephron epithelium relationship: part_of GO:0072009 ! nephron epithelium development relationship: part_of GO:0072028 ! nephron morphogenesis relationship: results_in_morphogenesis_of UBERON:0004211 ! nephron epithelium created_by: mah creation_date: 2010-02-08T01:19:06Z [Term] id: GO:0072089 name: stem cell proliferation namespace: biological_process def: "The multiplication or reproduction of stem cells, resulting in the expansion of a stem cell population. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [GOC:mtg_kidney_jan10] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000034 ! stem cell relationship: acts_on_population_of CL:0000034 ! stem cell relationship: has_part GO:0017145 ! stem cell division created_by: mah creation_date: 2010-02-08T02:03:36Z [Term] id: GO:0072091 name: regulation of stem cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of stem cell proliferation. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [GOC:mtg_kidney_jan10] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0072089 ! stem cell proliferation relationship: regulates GO:0072089 ! stem cell proliferation created_by: mah creation_date: 2010-02-08T02:09:03Z [Term] id: GO:0072093 name: metanephric renal vesicle formation namespace: biological_process def: "The developmental process pertaining to the initial formation of the metanephros." [GOC:mtg_kidney_jan10] synonym: "metanephros formation" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0072033 ! renal vesicle formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0005147 ! metanephric renal vesicle relationship: part_of GO:0072283 ! metanephric renal vesicle morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0005147 ! metanephric renal vesicle created_by: mah creation_date: 2010-02-10T01:17:11Z [Term] id: GO:0072098 name: anterior/posterior pattern specification involved in kidney development namespace: biological_process def: "The developmental process that results in the creation of defined areas or spaces within the kidney along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate." [GOC:mtg_kidney_jan10] synonym: "anterior/posterior pattern formation involved in kidney development" RELATED [GOC:mtg_kidney_jan10] synonym: "kidney anterior/posterior pattern formation" RELATED [GOC:mtg_kidney_jan10] synonym: "kidney anterior/posterior pattern specification" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0009952 ! anterior/posterior pattern specification is_a: GO:0061004 ! pattern specification involved in kidney development intersection_of: GO:0009952 ! anterior/posterior pattern specification intersection_of: part_of GO:0001822 ! kidney development created_by: mah creation_date: 2010-02-10T02:06:24Z [Term] id: GO:0072099 name: anterior/posterior pattern specification involved in ureteric bud development namespace: biological_process def: "The developmental process that results in the creation of defined areas or spaces within the ureteric bud along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate." [GOC:mtg_kidney_jan10] synonym: "ureteric bud anterior/posterior pattern formation" RELATED [GOC:mtg_kidney_jan10] is_a: GO:0061227 ! pattern specification involved in mesonephros development is_a: GO:0072098 ! anterior/posterior pattern specification involved in kidney development intersection_of: GO:0009952 ! anterior/posterior pattern specification intersection_of: part_of GO:0001657 ! ureteric bud development relationship: part_of GO:0001657 ! ureteric bud development created_by: mah creation_date: 2010-02-10T02:12:09Z [Term] id: GO:0072105 name: ureteric peristalsis namespace: biological_process def: "A wavelike sequence of involuntary muscular contraction and relaxation that passes along the ureter, impelling the contents onwards. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder." [GOC:mtg_kidney_jan10] is_a: GO:0014849 ! ureter smooth muscle contraction is_a: GO:0030432 ! peristalsis intersection_of: GO:0030432 ! peristalsis intersection_of: occurs_in UBERON:0000056 ! ureter relationship: occurs_in UBERON:0000056 ! ureter created_by: mah creation_date: 2010-02-10T03:07:54Z [Term] id: GO:0072106 name: regulation of ureteric bud formation namespace: biological_process def: "Any process that modulates the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct." [GOC:mtg_kidney_jan10] is_a: GO:0061217 ! regulation of mesonephros development is_a: GO:1905276 ! regulation of epithelial tube formation is_a: GO:2000027 ! regulation of animal organ morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060676 ! ureteric bud formation relationship: regulates GO:0060676 ! ureteric bud formation created_by: mah creation_date: 2010-02-12T02:34:40Z [Term] id: GO:0072107 name: positive regulation of ureteric bud formation namespace: biological_process def: "Any process that increases the rate or extent of the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct." [GOC:mtg_kidney_jan10] is_a: GO:0072106 ! regulation of ureteric bud formation is_a: GO:0110110 ! positive regulation of animal organ morphogenesis is_a: GO:1905278 ! positive regulation of epithelial tube formation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060676 ! ureteric bud formation relationship: positively_regulates GO:0060676 ! ureteric bud formation created_by: mah creation_date: 2010-02-12T02:37:28Z [Term] id: GO:0072108 name: positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis namespace: biological_process def: "Any process that increases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0003339 ! regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium is_a: GO:2000698 ! positive regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0003337 ! mesenchymal to epithelial transition involved in metanephros morphogenesis relationship: positively_regulates GO:0003337 ! mesenchymal to epithelial transition involved in metanephros morphogenesis created_by: mah creation_date: 2010-02-12T02:45:57Z [Term] id: GO:0072111 name: cell proliferation involved in kidney development namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of the population in the kidney." [GOC:mtg_kidney_jan10] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: part_of GO:0001822 ! kidney development relationship: part_of GO:0001822 ! kidney development created_by: mah creation_date: 2010-02-22T10:48:45Z [Term] id: GO:0072114 name: pronephros morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the pronephros are generated and organized. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life." [GOC:mtg_kidney_jan10] synonym: "pronephric kidney morphogenesis" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0060993 ! kidney morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002120 ! pronephros relationship: part_of GO:0048793 ! pronephros development relationship: results_in_morphogenesis_of UBERON:0002120 ! pronephros created_by: mah creation_date: 2010-02-22T11:12:15Z [Term] id: GO:0072116 name: pronephros formation namespace: biological_process def: "The developmental process pertaining to the initial formation of the pronephros. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life." [GOC:mtg_kidney_jan10] synonym: "pronephric kidney formation" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0048645 ! animal organ formation is_a: GO:0072003 ! kidney rudiment formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0002120 ! pronephros relationship: part_of GO:0072114 ! pronephros morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0002120 ! pronephros created_by: mah creation_date: 2010-02-22T11:16:26Z [Term] id: GO:0072120 name: pronephros maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for the pronephros to attain its fully functional state. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life." [GOC:mtg_kidney_jan10] synonym: "pronephric kidney maturation" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0048799 ! animal organ maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of UBERON:0002120 ! pronephros relationship: part_of GO:0048793 ! pronephros development relationship: results_in_maturation_of UBERON:0002120 ! pronephros created_by: mah creation_date: 2010-02-22T11:25:48Z [Term] id: GO:0072127 name: renal capsule development namespace: biological_process def: "The process whose specific outcome is the progression of the renal capsule over time, from its formation to the mature structure. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands." [GOC:mtg_kidney_jan10] is_a: GO:0061448 ! connective tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002015 ! kidney capsule relationship: part_of GO:0001822 ! kidney development relationship: results_in_development_of UBERON:0002015 ! kidney capsule created_by: mah creation_date: 2010-02-22T02:02:55Z [Term] id: GO:0072128 name: renal capsule morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the renal capsule are generated and organized. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands." [GOC:mtg_kidney_jan10] is_a: GO:0048729 ! tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002015 ! kidney capsule relationship: part_of GO:0072127 ! renal capsule development relationship: results_in_morphogenesis_of UBERON:0002015 ! kidney capsule created_by: mah creation_date: 2010-02-22T02:06:19Z [Term] id: GO:0072129 name: renal capsule formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a renal capsule from unspecified parts. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands." [GOC:mtg_kidney_jan10] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0002015 ! kidney capsule relationship: part_of GO:0072128 ! renal capsule morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0002015 ! kidney capsule created_by: mah creation_date: 2010-02-22T02:08:14Z [Term] id: GO:0072131 name: kidney mesenchyme morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a kidney mesenchymal tissue are generated and organized. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney." [GOC:mtg_kidney_jan10] is_a: GO:0072132 ! mesenchyme morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003918 ! kidney mesenchyme relationship: part_of GO:0072074 ! kidney mesenchyme development relationship: results_in_morphogenesis_of UBERON:0003918 ! kidney mesenchyme created_by: mah creation_date: 2010-02-22T02:16:43Z [Term] id: GO:0072132 name: mesenchyme morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a mesenchymal tissue are generated and organized. A mesenchymal tissue is made up of loosely packed stellate cells." [GOC:mtg_kidney_jan10] is_a: GO:0048729 ! tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003104 ! mesenchyme relationship: part_of GO:0009887 ! animal organ morphogenesis relationship: part_of GO:0060485 ! mesenchyme development relationship: results_in_morphogenesis_of UBERON:0003104 ! mesenchyme created_by: mah creation_date: 2010-02-22T02:17:15Z [Term] id: GO:0072133 name: metanephric mesenchyme morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a metanephric mesenchymal tissue are generated and organized. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0072131 ! kidney mesenchyme morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003220 ! metanephric mesenchyme relationship: part_of GO:0072075 ! metanephric mesenchyme development relationship: results_in_morphogenesis_of UBERON:0003220 ! metanephric mesenchyme created_by: mah creation_date: 2010-02-22T02:20:14Z [Term] id: GO:0072134 name: nephrogenic mesenchyme morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a nephrogenic mesenchymal tissue are generated and organized. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron." [GOC:mtg_kidney_jan10] is_a: GO:0072131 ! kidney mesenchyme morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0004208 ! nephrogenic mesenchyme relationship: part_of GO:0072076 ! nephrogenic mesenchyme development relationship: results_in_morphogenesis_of UBERON:0004208 ! nephrogenic mesenchyme created_by: mah creation_date: 2010-02-22T02:21:16Z [Term] id: GO:0072138 name: mesenchymal cell proliferation involved in ureteric bud development namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureteric bud, that contributes to ureteric bud development." [GOC:mtg_kidney_jan10] synonym: "ureteric bud mesenchymal cell proliferation" BROAD [GOC:mtg_kidney_jan10] is_a: GO:0010463 ! mesenchymal cell proliferation is_a: GO:0061209 ! cell proliferation involved in mesonephros development intersection_of: GO:0010463 ! mesenchymal cell proliferation intersection_of: part_of GO:0001657 ! ureteric bud development relationship: part_of GO:0001657 ! ureteric bud development created_by: mah creation_date: 2010-02-22T02:40:38Z [Term] id: GO:0072141 name: renal interstitial fibroblast development namespace: biological_process def: "The process whose specific outcome is the progression of a renal interstitial fibroblast over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10] synonym: "kidney interstitial cell development" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0048468 ! cell development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of CL:1000692 ! kidney interstitial fibroblast relationship: part_of GO:0072071 ! kidney interstitial fibroblast differentiation relationship: results_in_development_of CL:1000692 ! kidney interstitial fibroblast created_by: mah creation_date: 2010-02-24T01:39:05Z [Term] id: GO:0072155 name: epithelial cell migration involved in nephron tubule morphogenesis namespace: biological_process def: "The orderly movement of epithelial cells within a renal tubule that contributes to nephron tubule morphogenesis." [GOC:mtg_kidney_jan10] is_a: GO:0010631 ! epithelial cell migration is_a: GO:0035787 ! cell migration involved in kidney development intersection_of: GO:0010631 ! epithelial cell migration intersection_of: part_of GO:0072078 ! nephron tubule morphogenesis relationship: part_of GO:0072078 ! nephron tubule morphogenesis created_by: mah creation_date: 2010-02-24T02:21:25Z [Term] id: GO:0072160 name: nephron tubule epithelial cell differentiation namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the nephron tubule as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] is_a: GO:0035850 ! epithelial cell differentiation involved in kidney development intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:1000494 ! nephron tubule epithelial cell relationship: part_of GO:0072080 ! nephron tubule development relationship: results_in_acquisition_of_features_of CL:1000494 ! nephron tubule epithelial cell created_by: mah creation_date: 2010-02-24T02:40:11Z [Term] id: GO:0072161 name: mesenchymal cell differentiation involved in kidney development namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the kidney as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] is_a: GO:0061005 ! cell differentiation involved in kidney development is_a: GO:2001012 ! mesenchymal cell differentiation involved in renal system development intersection_of: GO:0048762 ! mesenchymal cell differentiation intersection_of: part_of GO:0001822 ! kidney development relationship: part_of GO:0072074 ! kidney mesenchyme development created_by: mah creation_date: 2010-02-26T01:31:49Z [Term] id: GO:0072163 name: mesonephric epithelium development namespace: biological_process def: "The process whose specific outcome is the progression of an epithelium in the mesonephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure." [GOC:mtg_kidney_jan10] is_a: GO:0072073 ! kidney epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005103 ! mesonephric epithelium relationship: part_of GO:0001823 ! mesonephros development relationship: results_in_development_of UBERON:0005103 ! mesonephric epithelium created_by: mah creation_date: 2010-02-26T01:40:43Z [Term] id: GO:0072164 name: mesonephric tubule development namespace: biological_process def: "The progression of a mesonephric tubule over time, from its initial formation to the mature structure. A mesonephric tubule is an epithelial tube that is part of the mesonephros." [GOC:mtg_kidney_jan10] is_a: GO:0035295 ! tube development is_a: GO:0072163 ! mesonephric epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000083 ! mesonephric tubule relationship: results_in_development_of UBERON:0000083 ! mesonephric tubule created_by: mah creation_date: 2010-02-26T01:45:58Z [Term] id: GO:0072170 name: metanephric tubule development namespace: biological_process def: "The progression of a metanephric tubule over time, from its initial formation to the mature structure. A metanephric tubule is an epithelial tube that is part of the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0035295 ! tube development is_a: GO:0072207 ! metanephric epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005106 ! metanephric tubule relationship: results_in_development_of UBERON:0005106 ! metanephric tubule created_by: mah creation_date: 2010-02-26T01:58:18Z [Term] id: GO:0072171 name: mesonephric tubule morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a mesonephric tubule are generated and organized. A mesonephric tubule is an epithelial tube that is part of the mesonephros." [GOC:mtg_kidney_jan10] is_a: GO:0072078 ! nephron tubule morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000083 ! mesonephric tubule relationship: part_of GO:0072164 ! mesonephric tubule development relationship: results_in_morphogenesis_of UBERON:0000083 ! mesonephric tubule created_by: mah creation_date: 2010-02-26T02:02:13Z [Term] id: GO:0072172 name: mesonephric tubule formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a mesonephric tubule from unspecified parts. A mesonephric tubule is an epithelial tube that is part of the mesonephros." [GOC:mtg_kidney_jan10] is_a: GO:0072079 ! nephron tubule formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0000083 ! mesonephric tubule relationship: part_of GO:0072171 ! mesonephric tubule morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0000083 ! mesonephric tubule created_by: mah creation_date: 2010-02-26T02:02:37Z [Term] id: GO:0072173 name: metanephric tubule morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a metanephric tubule are generated and organized from an epithelium. A metanephric tubule is an epithelial tube that is part of the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0060562 ! epithelial tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0005106 ! metanephric tubule relationship: part_of GO:0072170 ! metanephric tubule development relationship: results_in_morphogenesis_of UBERON:0005106 ! metanephric tubule created_by: mah creation_date: 2010-02-26T02:06:42Z [Term] id: GO:0072174 name: metanephric tubule formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a metanephric tubule." [GOC:mtg_kidney_jan10] is_a: GO:0072175 ! epithelial tube formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0005106 ! metanephric tubule relationship: part_of GO:0072173 ! metanephric tubule morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0005106 ! metanephric tubule created_by: mah creation_date: 2010-02-26T02:07:41Z [Term] id: GO:0072175 name: epithelial tube formation namespace: biological_process def: "The developmental process pertaining to the initial formation of an epithelial tube." [GOC:mtg_kidney_jan10] is_a: GO:0035148 ! tube formation intersection_of: GO:0035148 ! tube formation intersection_of: results_in_formation_of_anatomical_entity UBERON:0003914 ! epithelial tube relationship: part_of GO:0060562 ! epithelial tube morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0003914 ! epithelial tube property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22302" xsd:anyURI created_by: mah creation_date: 2010-02-26T02:15:40Z [Term] id: GO:0072176 name: nephric duct development namespace: biological_process def: "The process whose specific outcome is the progression of a nephric duct over time, from its initial formation to a mature structure. A nephric duct is a tube that drains a primitive kidney." [GOC:mtg_kidney_jan10] is_a: GO:0035295 ! tube development is_a: GO:0072073 ! kidney epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0009201 ! nephric duct relationship: results_in_development_of UBERON:0009201 ! nephric duct created_by: mah creation_date: 2010-02-26T02:27:31Z [Term] id: GO:0072177 name: mesonephric duct development namespace: biological_process def: "The process whose specific outcome is the progression of a mesonephric duct over time, from its initial formation to a mature structure. A mesonephric duct is a tube drains the mesonephros." [GOC:mtg_kidney_jan10] synonym: "Wolffian duct development" EXACT [GOC:dph] is_a: GO:0072164 ! mesonephric tubule development is_a: GO:0072176 ! nephric duct development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003074 ! mesonephric duct relationship: results_in_development_of UBERON:0003074 ! mesonephric duct created_by: mah creation_date: 2010-02-26T02:32:22Z [Term] id: GO:0072178 name: nephric duct morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the nephric duct are generated and organized. A nephric duct is a tube that drains a primitive kidney." [GOC:mtg_kidney_jan10] is_a: GO:0060562 ! epithelial tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0009201 ! nephric duct relationship: part_of GO:0072176 ! nephric duct development relationship: results_in_morphogenesis_of UBERON:0009201 ! nephric duct created_by: mah creation_date: 2010-02-26T02:35:29Z [Term] id: GO:0072179 name: nephric duct formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a nephric duct. A nephric duct is a tube that drains a primitive kidney." [GOC:mtg_kidney_jan10] is_a: GO:0072175 ! epithelial tube formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0009201 ! nephric duct relationship: part_of GO:0072178 ! nephric duct morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0009201 ! nephric duct created_by: mah creation_date: 2010-02-26T02:35:55Z [Term] id: GO:0072180 name: mesonephric duct morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the mesonephric duct are generated and organized. A mesonephric duct is a tube drains the mesonephros." [GOC:mtg_kidney_jan10] synonym: "Wolffian duct morphogenesis" RELATED [GOC:dph] is_a: GO:0072171 ! mesonephric tubule morphogenesis is_a: GO:0072178 ! nephric duct morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003074 ! mesonephric duct relationship: part_of GO:0072177 ! mesonephric duct development relationship: results_in_morphogenesis_of UBERON:0003074 ! mesonephric duct created_by: mah creation_date: 2010-02-26T02:37:13Z [Term] id: GO:0072181 name: mesonephric duct formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a mesonephric duct. A mesonephric duct is a tube that drains the mesonephros." [GOC:mtg_kidney_jan10] synonym: "Wolffian duct formation" EXACT [GOC:dph] is_a: GO:0072172 ! mesonephric tubule formation is_a: GO:0072179 ! nephric duct formation is_a: GO:0072180 ! mesonephric duct morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0003074 ! mesonephric duct relationship: results_in_formation_of_anatomical_entity UBERON:0003074 ! mesonephric duct created_by: mah creation_date: 2010-02-26T02:38:03Z [Term] id: GO:0072182 name: regulation of nephron tubule epithelial cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of nephron tubule epithelial cell differentiation." [GOC:mtg_kidney_jan10] is_a: GO:2000696 ! regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0072160 ! nephron tubule epithelial cell differentiation relationship: regulates GO:0072160 ! nephron tubule epithelial cell differentiation created_by: mah creation_date: 2010-02-26T02:45:09Z [Term] id: GO:0072183 name: negative regulation of nephron tubule epithelial cell differentiation namespace: biological_process def: "Any process that decreases the frequency, rate or extent of nephron tubule epithelial cell differentiation." [GOC:mtg_kidney_jan10] is_a: GO:0072182 ! regulation of nephron tubule epithelial cell differentiation is_a: GO:0090185 ! negative regulation of kidney development is_a: GO:2000697 ! negative regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0072160 ! nephron tubule epithelial cell differentiation relationship: negatively_regulates GO:0072160 ! nephron tubule epithelial cell differentiation created_by: mah creation_date: 2010-02-26T02:47:25Z [Term] id: GO:0072189 name: ureter development namespace: biological_process def: "The process whose specific outcome is the progression of the ureter over time, from its formation to the mature structure. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut." [GOC:mtg_kidney_jan10] is_a: GO:0035295 ! tube development is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000056 ! ureter relationship: part_of GO:0072001 ! renal system development relationship: results_in_development_of UBERON:0000056 ! ureter created_by: mah creation_date: 2010-03-01T01:44:14Z [Term] id: GO:0072191 name: ureter smooth muscle development namespace: biological_process def: "The process whose specific outcome is the progression of smooth muscle in the ureter over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10] is_a: GO:0048745 ! smooth muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0009919 ! ureter smooth muscle relationship: part_of GO:0072189 ! ureter development relationship: results_in_development_of UBERON:0009919 ! ureter smooth muscle created_by: mah creation_date: 2010-03-01T01:48:53Z [Term] id: GO:0072193 name: ureter smooth muscle cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell in the ureter." [GOC:mtg_kidney_jan10] is_a: GO:0051145 ! smooth muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:1000979 ! ureter smooth muscle cell relationship: part_of GO:0072191 ! ureter smooth muscle development relationship: results_in_acquisition_of_features_of CL:1000979 ! ureter smooth muscle cell created_by: mah creation_date: 2010-03-01T01:55:01Z [Term] id: GO:0072194 name: kidney smooth muscle tissue development namespace: biological_process def: "The process whose specific outcome is the progression of smooth muscle in the kidney over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10] is_a: GO:0048745 ! smooth muscle tissue development relationship: part_of GO:0001822 ! kidney development created_by: mah creation_date: 2010-03-01T02:05:30Z [Term] id: GO:0072197 name: ureter morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the ureter are generated and organized. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder." [GOC:mtg_kidney_jan10] is_a: GO:0009887 ! animal organ morphogenesis is_a: GO:0035239 ! tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000056 ! ureter relationship: part_of GO:0072189 ! ureter development relationship: results_in_morphogenesis_of UBERON:0000056 ! ureter created_by: mah creation_date: 2010-03-01T02:24:55Z [Term] id: GO:0072198 name: mesenchymal cell proliferation involved in ureter development namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureter, that contributes to ureter development." [GOC:mtg_kidney_jan10] synonym: "ureter mesenchymal cell proliferation" RELATED [GOC:mtg_kidney_jan10] synonym: "ureteral mesenchymal cell proliferation" RELATED [GOC:mtg_kidney_jan10] is_a: GO:0010463 ! mesenchymal cell proliferation intersection_of: GO:0010463 ! mesenchymal cell proliferation intersection_of: part_of GO:0072189 ! ureter development relationship: part_of GO:0072189 ! ureter development created_by: mah creation_date: 2010-03-01T03:24:41Z [Term] id: GO:0072199 name: regulation of mesenchymal cell proliferation involved in ureter development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." [GOC:mtg_kidney_jan10] synonym: "regulation of ureter mesenchymal cell proliferation" RELATED [GOC:mtg_kidney_jan10] synonym: "regulation of ureteral mesenchymal cell proliferation" RELATED [GOC:mtg_kidney_jan10] is_a: GO:0010464 ! regulation of mesenchymal cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0072198 ! mesenchymal cell proliferation involved in ureter development relationship: regulates GO:0072198 ! mesenchymal cell proliferation involved in ureter development created_by: mah creation_date: 2010-03-01T03:38:13Z [Term] id: GO:0072200 name: negative regulation of mesenchymal cell proliferation involved in ureter development namespace: biological_process def: "Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." [GOC:mtg_kidney_jan10] synonym: "negative regulation of ureter mesenchymal cell proliferation" RELATED [GOC:mtg_kidney_jan10] synonym: "negative regulation of ureteral mesenchymal cell proliferation" RELATED [GOC:mtg_kidney_jan10] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:0072199 ! regulation of mesenchymal cell proliferation involved in ureter development is_a: GO:0072201 ! negative regulation of mesenchymal cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0072198 ! mesenchymal cell proliferation involved in ureter development relationship: negatively_regulates GO:0072198 ! mesenchymal cell proliferation involved in ureter development created_by: mah creation_date: 2010-03-01T03:42:31Z [Term] id: GO:0072201 name: negative regulation of mesenchymal cell proliferation namespace: biological_process def: "Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." [GOC:mtg_kidney_jan10] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0010464 ! regulation of mesenchymal cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0010463 ! mesenchymal cell proliferation relationship: negatively_regulates GO:0010463 ! mesenchymal cell proliferation created_by: mah creation_date: 2010-03-01T03:43:29Z [Term] id: GO:0072202 name: cell differentiation involved in metanephros development namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephros as it progresses from its formation to the mature state." [GOC:mah, GOC:mtg_kidney_jan10] is_a: GO:0061005 ! cell differentiation involved in kidney development intersection_of: GO:0030154 ! cell differentiation intersection_of: part_of GO:0001656 ! metanephros development relationship: part_of GO:0001656 ! metanephros development created_by: mah creation_date: 2010-03-18T10:40:14Z [Term] id: GO:0072203 name: cell proliferation involved in metanephros development namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of the population in the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0072111 ! cell proliferation involved in kidney development intersection_of: GO:0008283 ! cell population proliferation intersection_of: part_of GO:0001656 ! metanephros development relationship: part_of GO:0001656 ! metanephros development created_by: mah creation_date: 2010-03-18T10:42:27Z [Term] id: GO:0072204 name: cell-cell signaling involved in metanephros development namespace: biological_process def: "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the metanephros over time, from its formation to the mature organ." [GOC:mtg_kidney_jan10] synonym: "cell-cell signalling involved in metanephros development" EXACT [GOC:mah] is_a: GO:0060995 ! cell-cell signaling involved in kidney development intersection_of: GO:0007267 ! cell-cell signaling intersection_of: part_of GO:0001656 ! metanephros development relationship: part_of GO:0001656 ! metanephros development created_by: mah creation_date: 2010-03-18T10:54:36Z [Term] id: GO:0072205 name: metanephric collecting duct development namespace: biological_process def: "The process whose specific outcome is the progression of a collecting duct in the metanephros over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder." [GOC:mtg_kidney_jan10] is_a: GO:0072044 ! collecting duct development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004737 ! metanephric collecting duct relationship: part_of GO:0001656 ! metanephros development relationship: results_in_development_of UBERON:0004737 ! metanephric collecting duct created_by: mah creation_date: 2010-03-18T11:15:37Z [Term] id: GO:0072207 name: metanephric epithelium development namespace: biological_process def: "The process whose specific outcome is the progression of an epithelium in the metanephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure." [GOC:mtg_kidney_jan10] is_a: GO:0072073 ! kidney epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005108 ! metanephric epithelium relationship: part_of GO:0001656 ! metanephros development relationship: results_in_development_of UBERON:0005108 ! metanephric epithelium created_by: mah creation_date: 2010-03-18T11:50:37Z [Term] id: GO:0072208 name: metanephric smooth muscle tissue development namespace: biological_process def: "The process whose specific outcome is the progression of smooth muscle in the metanephros over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10] is_a: GO:0072194 ! kidney smooth muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005109 ! metanephric smooth muscle tissue relationship: part_of GO:0001656 ! metanephros development relationship: results_in_development_of UBERON:0005109 ! metanephric smooth muscle tissue created_by: mah creation_date: 2010-03-18T11:51:59Z [Term] id: GO:0072210 name: metanephric nephron development namespace: biological_process def: "The process whose specific outcome is the progression of a nephron in the metanephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney." [GOC:mtg_kidney_jan10] is_a: GO:0072006 ! nephron development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005110 ! metanephric nephron relationship: part_of GO:0001656 ! metanephros development relationship: results_in_development_of UBERON:0005110 ! metanephric nephron created_by: mah creation_date: 2010-03-18T12:52:57Z [Term] id: GO:0072213 name: metanephric capsule development namespace: biological_process def: "The process whose specific outcome is the progression of the metanephric capsule over time, from its formation to the mature structure. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage." [GOC:mtg_kidney_jan10] is_a: GO:0072127 ! renal capsule development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005137 ! metanephric capsule relationship: part_of GO:0001656 ! metanephros development relationship: results_in_development_of UBERON:0005137 ! metanephric capsule created_by: mah creation_date: 2010-03-18T01:25:19Z [Term] id: GO:0072214 name: metanephric cortex development namespace: biological_process def: "The process whose specific outcome is the progression of the metanephric cortex over time, from its formation to the mature structure. The metanephric cortex is the outer region of the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0060485 ! mesenchyme development is_a: GO:0072055 ! renal cortex development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005113 ! metanephric cortex mesenchyme relationship: part_of GO:0001656 ! metanephros development relationship: results_in_development_of UBERON:0005113 ! metanephric cortex mesenchyme created_by: mah creation_date: 2010-03-18T01:29:49Z [Term] id: GO:0072215 name: regulation of metanephros development namespace: biological_process def: "Any process that modulates the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10] is_a: GO:0090183 ! regulation of kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001656 ! metanephros development relationship: regulates GO:0001656 ! metanephros development [Term] id: GO:0072216 name: positive regulation of metanephros development namespace: biological_process def: "Any process that increases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10] is_a: GO:0072215 ! regulation of metanephros development is_a: GO:0090184 ! positive regulation of kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001656 ! metanephros development relationship: positively_regulates GO:0001656 ! metanephros development created_by: mah creation_date: 2010-03-18T01:40:12Z [Term] id: GO:0072217 name: negative regulation of metanephros development namespace: biological_process def: "Any process that decreases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10] is_a: GO:0072215 ! regulation of metanephros development is_a: GO:0090185 ! negative regulation of kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001656 ! metanephros development relationship: negatively_regulates GO:0001656 ! metanephros development created_by: mah creation_date: 2010-03-18T01:45:48Z [Term] id: GO:0072219 name: metanephric cortical collecting duct development namespace: biological_process def: "The process whose specific outcome is the progression of the metanephric cortical collecting duct over time, from its formation to the mature structure. The metanephric cortical collecting duct is the portion of the metanephric collecting duct that resides in the renal cortex." [GOC:mtg_kidney_jan10] is_a: GO:0072059 ! cortical collecting duct development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005115 ! metanephric cortical collecting duct relationship: results_in_development_of UBERON:0005115 ! metanephric cortical collecting duct created_by: mah creation_date: 2010-03-18T03:34:52Z [Term] id: GO:0072234 name: metanephric nephron tubule development namespace: biological_process def: "The progression of a metanephric nephron tubule over time, from its initial formation to the mature structure. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0072080 ! nephron tubule development is_a: GO:0072170 ! metanephric tubule development is_a: GO:0072243 ! metanephric nephron epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005146 ! metanephric nephron tubule relationship: results_in_development_of UBERON:0005146 ! metanephric nephron tubule created_by: mah creation_date: 2010-03-18T03:41:23Z [Term] id: GO:0072243 name: metanephric nephron epithelium development namespace: biological_process def: "The process whose specific outcome is the progression of the metanephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The metanephric nephron epithelium is a tissue that covers the surface of a nephron in the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0072009 ! nephron epithelium development is_a: GO:0072207 ! metanephric epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005134 ! metanephric nephron epithelium relationship: results_in_development_of UBERON:0005134 ! metanephric nephron epithelium created_by: mah creation_date: 2010-03-19T03:29:49Z [Term] id: GO:0072257 name: metanephric nephron tubule epithelial cell differentiation namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephric nephron tubule as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] is_a: GO:0072160 ! nephron tubule epithelial cell differentiation is_a: GO:0072202 ! cell differentiation involved in metanephros development intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:1000123 ! metanephric nephron tubule epithelial cell relationship: part_of GO:0072234 ! metanephric nephron tubule development relationship: results_in_acquisition_of_features_of CL:1000123 ! metanephric nephron tubule epithelial cell created_by: mah creation_date: 2010-03-19T04:11:02Z [Term] id: GO:0072265 name: metanephric capsule morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the metanephric capsule are generated and organized. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage." [GOC:mtg_kidney_jan10] is_a: GO:0072128 ! renal capsule morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0005137 ! metanephric capsule relationship: part_of GO:0072213 ! metanephric capsule development relationship: results_in_morphogenesis_of UBERON:0005137 ! metanephric capsule created_by: mah creation_date: 2010-03-30T02:54:49Z [Term] id: GO:0072266 name: metanephric capsule formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a metanephric capsule from unspecified parts. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage." [GOC:mtg_kidney_jan10] is_a: GO:0072129 ! renal capsule formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0005137 ! metanephric capsule relationship: part_of GO:0072265 ! metanephric capsule morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0005137 ! metanephric capsule created_by: mah creation_date: 2010-03-30T02:56:35Z [Term] id: GO:0072268 name: pattern specification involved in metanephros development namespace: biological_process def: "Any developmental process that results in the creation of defined areas or spaces within the metanephros to which cells respond and eventually are instructed to differentiate." [GOC:mtg_kidney_jan10] synonym: "metanephros pattern formation" RELATED [GOC:mtg_kidney_jan10] synonym: "metanephros pattern specification" EXACT [GOC:mtg_kidney_jan10] synonym: "pattern formation involved in metanephros development" RELATED [GOC:mtg_kidney_jan10] is_a: GO:0061004 ! pattern specification involved in kidney development intersection_of: GO:0007389 ! pattern specification process intersection_of: part_of GO:0001656 ! metanephros development relationship: part_of GO:0001656 ! metanephros development created_by: mah creation_date: 2010-03-30T03:06:30Z [Term] id: GO:0072273 name: metanephric nephron morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the metanephric nephron are generated and organized. A metanephric nephron is the functional unit of the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0072028 ! nephron morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0005110 ! metanephric nephron relationship: part_of GO:0003338 ! metanephros morphogenesis relationship: part_of GO:0072210 ! metanephric nephron development relationship: results_in_morphogenesis_of UBERON:0005110 ! metanephric nephron created_by: mah creation_date: 2010-03-30T03:33:19Z [Term] id: GO:0072282 name: metanephric nephron tubule morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a metanephric nephron tubule are generated and organized. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0072078 ! nephron tubule morphogenesis is_a: GO:0072173 ! metanephric tubule morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0005146 ! metanephric nephron tubule relationship: part_of GO:0072234 ! metanephric nephron tubule development relationship: part_of GO:0072273 ! metanephric nephron morphogenesis relationship: results_in_morphogenesis_of UBERON:0005146 ! metanephric nephron tubule created_by: mah creation_date: 2010-04-01T03:25:11Z [Term] id: GO:0072283 name: metanephric renal vesicle morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the metanephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the metanephric nephron epithelium, and is formed by the condensation of mesenchymal cells." [GOC:mtg_kidney_jan10] is_a: GO:0072077 ! renal vesicle morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0005147 ! metanephric renal vesicle relationship: part_of GO:0072273 ! metanephric nephron morphogenesis relationship: results_in_morphogenesis_of UBERON:0005147 ! metanephric renal vesicle created_by: mah creation_date: 2010-04-01T03:28:00Z [Term] id: GO:0072285 name: mesenchymal to epithelial transition involved in metanephric renal vesicle formation namespace: biological_process def: "A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephric renal vesicle." [GOC:mtg_kidney_jan10] is_a: GO:0003337 ! mesenchymal to epithelial transition involved in metanephros morphogenesis is_a: GO:0072036 ! mesenchymal to epithelial transition involved in renal vesicle formation intersection_of: GO:0060231 ! mesenchymal to epithelial transition intersection_of: part_of GO:0072093 ! metanephric renal vesicle formation relationship: part_of GO:0072093 ! metanephric renal vesicle formation created_by: mah creation_date: 2010-04-01T03:43:31Z [Term] id: GO:0072289 name: metanephric nephron tubule formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a metanephric nephron tubule from unspecified parts. A metanephric nephron tubule is an epithelial tube that is part of a nephron in the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0072079 ! nephron tubule formation is_a: GO:0072174 ! metanephric tubule formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0005146 ! metanephric nephron tubule relationship: part_of GO:0072282 ! metanephric nephron tubule morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0005146 ! metanephric nephron tubule created_by: mah creation_date: 2010-04-09T03:47:44Z [Term] id: GO:0072290 name: epithelial cell migration involved in metanephric nephron tubule morphogenesis namespace: biological_process def: "The orderly movement of epithelial cells within a renal tubule that contributes to metanephric nephron tubule morphogenesis." [GOC:mtg_kidney_jan10] is_a: GO:0035788 ! cell migration involved in metanephros development is_a: GO:0072155 ! epithelial cell migration involved in nephron tubule morphogenesis intersection_of: GO:0010631 ! epithelial cell migration intersection_of: part_of GO:0072282 ! metanephric nephron tubule morphogenesis relationship: part_of GO:0072282 ! metanephric nephron tubule morphogenesis created_by: mah creation_date: 2010-04-09T03:52:29Z [Term] id: GO:0072304 name: regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis namespace: biological_process def: "Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] synonym: "regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis" NARROW [] synonym: "regulation of mesenchymal stem cell apoptotic process involved in metanephric nephron morphogenesis" EXACT [] is_a: GO:0072039 ! regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis is_a: GO:1900211 ! regulation of mesenchymal cell apoptotic process involved in metanephros development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1901147 ! mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis relationship: regulates GO:0072309 ! mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis relationship: regulates GO:1901147 ! mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis created_by: mah creation_date: 2010-04-09T05:03:41Z [Term] id: GO:0072305 name: negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis namespace: biological_process def: "Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] synonym: "negative regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis" NARROW [] synonym: "negative regulation of mesenchymal stem cell apoptotic process involved in metanephric nephron morphogenesis" EXACT [] is_a: GO:0072040 ! negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis is_a: GO:0072304 ! regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis is_a: GO:1900212 ! negative regulation of mesenchymal cell apoptotic process involved in metanephros development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1901147 ! mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis relationship: negatively_regulates GO:0072309 ! mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis relationship: negatively_regulates GO:1901147 ! mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis created_by: mah creation_date: 2010-04-09T05:03:41Z [Term] id: GO:0072306 name: positive regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis namespace: biological_process def: "Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] synonym: "positive regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis" NARROW [] synonym: "positive regulation of mesenchymal stem cell apoptotic process involved in metanephric nephron morphogenesis" EXACT [] is_a: GO:0072041 ! positive regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis is_a: GO:0072304 ! regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis is_a: GO:1900213 ! positive regulation of mesenchymal cell apoptotic process involved in metanephros development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1901147 ! mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis relationship: positively_regulates GO:0072309 ! mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis relationship: positively_regulates GO:1901147 ! mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis created_by: mah creation_date: 2010-04-09T05:03:41Z [Term] id: GO:0072307 name: regulation of metanephric nephron tubule epithelial cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation." [GOC:mtg_kidney_jan10] is_a: GO:0072182 ! regulation of nephron tubule epithelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0072257 ! metanephric nephron tubule epithelial cell differentiation relationship: regulates GO:0072257 ! metanephric nephron tubule epithelial cell differentiation created_by: mah creation_date: 2010-04-09T05:03:41Z [Term] id: GO:0072308 name: negative regulation of metanephric nephron tubule epithelial cell differentiation namespace: biological_process def: "Any process that decreases the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation." [GOC:mtg_kidney_jan10] is_a: GO:0072183 ! negative regulation of nephron tubule epithelial cell differentiation is_a: GO:0072307 ! regulation of metanephric nephron tubule epithelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0072257 ! metanephric nephron tubule epithelial cell differentiation relationship: negatively_regulates GO:0072257 ! metanephric nephron tubule epithelial cell differentiation created_by: mah creation_date: 2010-04-09T05:03:41Z [Term] id: GO:0072309 name: mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis namespace: biological_process def: "The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the metanephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells." [GOC:mtg_kidney_jan10] is_a: GO:0072038 ! mesenchymal stem cell maintenance involved in nephron morphogenesis relationship: part_of GO:0072273 ! metanephric nephron morphogenesis created_by: mah creation_date: 2010-04-09T05:03:41Z [Term] id: GO:0072329 name: monocarboxylic acid catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group." [GOC:mah] is_a: GO:0032787 ! monocarboxylic acid metabolic process is_a: GO:0046395 ! carboxylic acid catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:35757 ! monocarboxylic acid anion relationship: has_primary_input CHEBI:35757 ! monocarboxylic acid anion created_by: mah creation_date: 2010-11-02T04:41:55Z [Term] id: GO:0072330 name: monocarboxylic acid biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group." [GOC:mah] synonym: "monocarboxylic acid anabolism" EXACT [GOC:mah] synonym: "monocarboxylic acid biosynthesis" EXACT [GOC:mah] synonym: "monocarboxylic acid formation" EXACT [GOC:mah] synonym: "monocarboxylic acid synthesis" EXACT [GOC:mah] is_a: GO:0032787 ! monocarboxylic acid metabolic process is_a: GO:0046394 ! carboxylic acid biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:35757 ! monocarboxylic acid anion relationship: has_primary_output CHEBI:35757 ! monocarboxylic acid anion created_by: mah creation_date: 2010-11-02T04:51:32Z [Term] id: GO:0072348 name: sulfur compound transport namespace: biological_process def: "The directed movement of compounds that contain sulfur, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] synonym: "sulfur-containing compound transport" EXACT [GOC:mah] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:26835 ! sulfur molecular entity relationship: has_primary_input CHEBI:26835 ! sulfur molecular entity created_by: mah creation_date: 2010-11-11T11:43:56Z [Term] id: GO:0072359 name: circulatory system development namespace: biological_process alt_id: GO:0072358 def: "The process whose specific outcome is the progression of the circulatory system over time, from its formation to the mature structure. The circulatory system is the organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis." [GOC:mah, UBERON:0001009] subset: goslim_drosophila synonym: "cardiovascular system development" NARROW [] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001009 ! circulatory system relationship: results_in_development_of UBERON:0001009 ! circulatory system created_by: mah creation_date: 2010-11-16T11:27:39Z [Term] id: GO:0072360 name: vascular cord development namespace: biological_process def: "The progression of the vascular cord over time from its initial formation until its mature state. The vascular cord is the primordial vasculature that will develop into blood vessels by the process of tubulogenesis." [GOC:mah, PMID:7084422, ZFA:0005077] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0006965 ! vascular cord relationship: part_of GO:0072359 ! circulatory system development relationship: results_in_development_of UBERON:0006965 ! vascular cord created_by: mah creation_date: 2010-11-16T11:46:55Z [Term] id: GO:0072384 name: organelle transport along microtubule namespace: biological_process def: "The directed movement of an organelle along a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination." [GOC:mah] synonym: "microtubule-based organelle localization" EXACT [GOC:rl] is_a: GO:0010970 ! transport along microtubule is_a: GO:0051656 ! establishment of organelle localization intersection_of: GO:0046907 ! intracellular transport intersection_of: has_primary_input GO:0043226 ! organelle intersection_of: results_in_transport_along GO:0005874 ! microtubule created_by: mah creation_date: 2010-12-01T04:59:11Z [Term] id: GO:0072488 name: ammonium transmembrane transport namespace: biological_process alt_id: GO:0015696 def: "The process in which ammonium is transported across a membrane. Ammonium is the cation NH4+." [GOC:mah] comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "ammonia transport" BROAD [] synonym: "ammonium membrane transport" EXACT [] synonym: "ammonium transport" BROAD [] is_a: GO:0071705 ! nitrogen compound transport is_a: GO:0098662 ! inorganic cation transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:28938 ! ammonium intersection_of: results_in_transport_across GO:0016020 ! membrane relationship: has_primary_input CHEBI:28938 ! ammonium property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22228" xsd:anyURI created_by: mah creation_date: 2010-12-10T10:29:57Z [Term] id: GO:0072520 name: seminiferous tubule development namespace: biological_process def: "The reproductive developmental process whose specific outcome is the progression of the seminiferous tubule over time, from its formation to the mature structure. Seminiferous tubules are ducts located in the testicles, and are the specific location of meiosis, and the subsequent creation of gametes, namely spermatozoa." [GOC:BHF, GOC:mah, UBERON:0001343] is_a: GO:0035295 ! tube development is_a: GO:0048608 ! reproductive structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001343 ! seminiferous tubule of testis relationship: part_of GO:0008584 ! male gonad development relationship: results_in_development_of UBERON:0001343 ! seminiferous tubule of testis created_by: mah creation_date: 2011-01-04T12:50:36Z [Term] id: GO:0072537 name: fibroblast activation namespace: biological_process def: "A change in the morphology or behavior of a fibroblast resulting from exposure to an activating factor such as a cellular or soluble ligand." [CL:0000057, GOC:BHF, GOC:mah] is_a: GO:0001775 ! cell activation intersection_of: GO:0001775 ! cell activation intersection_of: has_primary_input CL:0000057 ! fibroblast relationship: has_primary_input CL:0000057 ! fibroblast created_by: mah creation_date: 2011-01-14T04:35:08Z [Term] id: GO:0072560 name: type B pancreatic cell maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for a type B pancreatic cell to attain its fully functional state. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin." [CL:0000169, GOC:BHF] comment: These processes continue to 60 DPA in Gossypium spp. synonym: "pancreatic B cell maturation" EXACT [CL:0000169, GOC:mah] synonym: "pancreatic beta cell maturation" EXACT [CL:0000169, GOC:mah] is_a: GO:0002071 ! glandular epithelial cell maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of CL:0000169 ! type B pancreatic cell relationship: part_of GO:0003323 ! type B pancreatic cell development relationship: results_in_maturation_of CL:0000169 ! type B pancreatic cell created_by: mah creation_date: 2011-01-27T01:57:14Z [Term] id: GO:0072575 name: epithelial cell proliferation involved in liver morphogenesis namespace: biological_process def: "The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the liver." [GOC:BHF, GOC:mah] is_a: GO:0050673 ! epithelial cell proliferation intersection_of: GO:0050673 ! epithelial cell proliferation intersection_of: part_of GO:0072576 ! liver morphogenesis relationship: part_of GO:0072576 ! liver morphogenesis created_by: mah creation_date: 2011-02-02T03:37:50Z [Term] id: GO:0072576 name: liver morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the liver are generated and organized." [GOC:mah] is_a: GO:0022612 ! gland morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002107 ! liver relationship: part_of GO:0001889 ! liver development relationship: results_in_morphogenesis_of UBERON:0002107 ! liver created_by: mah creation_date: 2011-02-02T03:41:30Z [Term] id: GO:0072577 name: endothelial cell apoptotic process namespace: biological_process def: "Any apoptotic process in an endothelial cell. An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal." [CL:0000115, GOC:BHF, GOC:mah, GOC:mtg_apoptosis] synonym: "apoptosis of endothelial cells" EXACT [GOC:mah] synonym: "endothelial cell apoptosis" NARROW [] synonym: "endothelial cell programmed cell death by apoptosis" EXACT [GOC:mah] synonym: "killing of endothelial cells" EXACT [GOC:mah] synonym: "programmed cell death of endothelial cells by apoptosis" EXACT [GOC:mah] synonym: "programmed cell death, endothelial cells" EXACT [GOC:mah] is_a: GO:1904019 ! epithelial cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000115 ! endothelial cell relationship: occurs_in CL:0000115 ! endothelial cell created_by: mah creation_date: 2011-02-02T03:56:24Z [Term] id: GO:0072592 name: oxygen metabolic process namespace: biological_process def: "The chemical reactions and pathways involving diatomic oxygen (O2)." [GOC:mah] synonym: "diatomic oxygen metabolic process" EXACT [CHEBI:33263] synonym: "oxygen metabolism" EXACT [GOC:mah] is_a: GO:0044237 ! cellular metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:15379 ! dioxygen relationship: has_primary_input_or_output CHEBI:15379 ! dioxygen created_by: mah creation_date: 2011-02-11T10:46:51Z [Term] id: GO:0072594 name: establishment of protein localization to organelle namespace: biological_process def: "The directed movement of a protein to a specific location on or in an organelle. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle." [GOC:mah] synonym: "establishment of protein localisation to organelle" EXACT [GOC:mah] is_a: GO:0045184 ! establishment of protein localization intersection_of: GO:0045184 ! establishment of protein localization intersection_of: has_target_end_location GO:0043226 ! organelle relationship: has_target_end_location GO:0043226 ! organelle created_by: mah creation_date: 2011-02-14T01:56:51Z [Term] id: GO:0072657 name: protein localization to membrane namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a specific location in a membrane." [GOC:mah] subset: goslim_prokaryote synonym: "protein localisation in membrane" EXACT [GOC:mah] synonym: "protein localization in membrane" EXACT [] is_a: GO:0008104 ! protein localization is_a: GO:0051668 ! localization within membrane intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0016020 ! membrane created_by: mah creation_date: 2011-02-14T02:35:18Z [Term] id: GO:0072659 name: protein localization to plasma membrane namespace: biological_process alt_id: GO:0072661 alt_id: GO:0090002 def: "A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane." [GOC:mah] subset: goslim_generic subset: goslim_pombe synonym: "protein localisation in plasma membrane" RELATED [GOC:mah] synonym: "protein localization in plasma membrane" RELATED [] synonym: "protein targeting to plasma membrane" RELATED [] synonym: "protein-plasma membrane targeting" RELATED [GOC:mah] is_a: GO:0072657 ! protein localization to membrane is_a: GO:1990778 ! protein localization to cell periphery intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0005886 ! plasma membrane intersection_of: has_target_start_location GO:0005622 ! intracellular anatomical structure relationship: has_target_end_location GO:0005886 ! plasma membrane relationship: has_target_start_location GO:0005622 ! intracellular anatomical structure created_by: tb creation_date: 2009-07-10T10:29:23Z [Term] id: GO:0072665 name: protein localization to vacuole namespace: biological_process def: "A process in which a protein is transported to, or maintained at, a location in a vacuole." [GOC:ecd] synonym: "protein localisation to vacuole" EXACT [GOC:mah] is_a: GO:0033365 ! protein localization to organelle intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0005773 ! vacuole relationship: has_target_end_location GO:0005773 ! vacuole created_by: mah creation_date: 2011-02-14T02:55:35Z [Term] id: GO:0072666 name: establishment of protein localization to vacuole namespace: biological_process def: "The directed movement of a protein to a specific location in a vacuole." [GOC:mah] synonym: "establishment of protein localisation to vacuole" EXACT [GOC:mah] is_a: GO:0072594 ! establishment of protein localization to organelle intersection_of: GO:0045184 ! establishment of protein localization intersection_of: has_target_end_location GO:0005773 ! vacuole relationship: has_target_end_location GO:0005773 ! vacuole created_by: mah creation_date: 2011-02-14T02:56:29Z [Term] id: GO:0072676 name: lymphocyte migration namespace: biological_process def: "The movement of a lymphocyte within or between different tissues and organs of the body." [CL:0000542, GOC:BHF, GOC:mah] is_a: GO:0071674 ! mononuclear cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000542 ! lymphocyte relationship: results_in_movement_of CL:0000542 ! lymphocyte created_by: mah creation_date: 2011-02-22T03:38:12Z [Term] id: GO:0072678 name: T cell migration namespace: biological_process def: "The movement of a T cell within or between different tissues and organs of the body." [CL:0000084, GOC:BHF, GOC:mah] synonym: "T lymphocyte migration" EXACT [CL:0000084] synonym: "T-cell migration" EXACT [CL:0000084] synonym: "T-lymphocyte migration" EXACT [CL:0000084] is_a: GO:0072676 ! lymphocyte migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000084 ! T cell relationship: results_in_movement_of CL:0000084 ! T cell created_by: mah creation_date: 2011-02-22T03:40:40Z [Term] id: GO:0072697 name: protein localization to cell cortex namespace: biological_process def: "A process in which a protein is transported to, or maintained in, the cell cortex." [GOC:mah] synonym: "protein localisation to cell cortex" EXACT [GOC:mah] is_a: GO:1990778 ! protein localization to cell periphery intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0005938 ! cell cortex relationship: has_target_end_location GO:0005938 ! cell cortex created_by: mah creation_date: 2012-04-11T01:16:33Z [Term] id: GO:0072698 name: protein localization to microtubule cytoskeleton namespace: biological_process def: "A cellular protein localization process in which a protein is transported to, or maintained at, a location within the microtubule cytoskeleton." [GOC:mah] synonym: "protein localisation to microtubule cytoskeleton" EXACT [GOC:mah] is_a: GO:0044380 ! protein localization to cytoskeleton intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0015630 ! microtubule cytoskeleton relationship: has_target_end_location GO:0015630 ! microtubule cytoskeleton created_by: mah creation_date: 2012-04-11T01:19:35Z [Term] id: GO:0080090 name: regulation of primary metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism." [PMID:19211694] is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0044238 ! primary metabolic process relationship: regulates GO:0044238 ! primary metabolic process created_by: dhl creation_date: 2009-04-22T04:30:52Z [Term] id: GO:0080134 name: regulation of response to stress namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." [GOC:dhl] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_manually_annotate is_a: GO:0048583 ! regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006950 ! response to stress relationship: regulates GO:0006950 ! response to stress created_by: dhl creation_date: 2009-05-06T04:51:28Z [Term] id: GO:0080154 name: regulation of fertilization namespace: biological_process def: "Any process that modulates the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy)." [GOC:DHL, PMID:20478994] is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0009566 ! fertilization relationship: regulates GO:0009566 ! fertilization created_by: dhl creation_date: 2010-09-01T03:44:27Z [Term] id: GO:0085029 name: extracellular matrix assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of the extracellular matrix." [GOC:jl] is_a: GO:0022607 ! cellular component assembly is_a: GO:0030198 ! extracellular matrix organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0031012 ! extracellular matrix relationship: results_in_assembly_of GO:0031012 ! extracellular matrix created_by: jl creation_date: 2010-07-14T12:52:49Z [Term] id: GO:0086001 name: cardiac muscle cell action potential namespace: biological_process def: "An action potential that occurs in a cardiac muscle cell." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] is_a: GO:0001508 ! action potential intersection_of: GO:0001508 ! action potential intersection_of: occurs_in CL:0000746 ! cardiac muscle cell relationship: occurs_in CL:0000746 ! cardiac muscle cell created_by: tb creation_date: 2011-11-10T07:45:11Z [Term] id: GO:0086015 name: SA node cell action potential namespace: biological_process def: "An action potential that occurs in a sinoatrial node cardiac muscle cell." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "SA node cardiac muscle cell action potential" EXACT [] synonym: "SAN cardiac muscle cell action potential" EXACT [] synonym: "sinoatrial node cardiac muscle cell action potential" EXACT [] synonym: "sinus node cardiac muscle cell action potential" NARROW [] is_a: GO:0086001 ! cardiac muscle cell action potential intersection_of: GO:0001508 ! action potential intersection_of: occurs_in CL:1000409 ! myocyte of sinoatrial node relationship: occurs_in CL:1000409 ! myocyte of sinoatrial node relationship: part_of GO:0086018 ! SA node cell to atrial cardiac muscle cell signaling created_by: tb creation_date: 2011-11-10T08:50:15Z [Term] id: GO:0086016 name: AV node cell action potential namespace: biological_process def: "An action potential that occurs in an atrioventricular node cardiac muscle cell." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "atrioventricular node cardiac muscle cell action potential" EXACT [] synonym: "AV node cardiac muscle cell action potential" EXACT [] is_a: GO:0086001 ! cardiac muscle cell action potential intersection_of: GO:0001508 ! action potential intersection_of: occurs_in CL:1000410 ! myocyte of atrioventricular node relationship: occurs_in CL:1000410 ! myocyte of atrioventricular node relationship: part_of GO:0086027 ! AV node cell to bundle of His cell signaling created_by: tb creation_date: 2011-11-10T08:58:56Z [Term] id: GO:0086017 name: Purkinje myocyte action potential namespace: biological_process def: "An action potential that occurs in a Purkinje myocyte." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] is_a: GO:0086001 ! cardiac muscle cell action potential intersection_of: GO:0001508 ! action potential intersection_of: occurs_in CL:0002068 ! Purkinje myocyte relationship: occurs_in CL:0002068 ! Purkinje myocyte relationship: part_of GO:0086029 ! Purkinje myocyte to ventricular cardiac muscle cell signaling created_by: tb creation_date: 2011-11-10T08:58:56Z [Term] id: GO:0086018 name: SA node cell to atrial cardiac muscle cell signaling namespace: biological_process def: "Any process that mediates the transfer of information from an SA node cardiomyocyte to an atrial cardiomyocyte." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "SA node cardiac muscle cell to atrial cardiac muscle cell signalling" EXACT [] synonym: "SA node cardiomyocyte to atrial cardiomyocyte signalling" EXACT [] synonym: "SAN cardiomyocyte to atrial cardiomyocyte signalling" EXACT [] synonym: "sinoatrial node cardiomyocyte to atrial cardiomyocyte signalling" EXACT [] synonym: "sinus node cardiomyocyte to atrial cardiomyocyte signalling" NARROW [] is_a: GO:0086019 ! cell-cell signaling involved in cardiac conduction is_a: GO:0086070 ! SA node cell to atrial cardiac muscle cell communication created_by: tb creation_date: 2011-11-10T09:15:01Z [Term] id: GO:0086019 name: cell-cell signaling involved in cardiac conduction namespace: biological_process def: "Any process that mediates the transfer of information from one cell to another and contributes to the heart process that regulates cardiac muscle contraction; beginning with the generation of an action potential in the sinoatrial node and ending with regulation of contraction of the myocardium." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "cell-cell signalling involved in cardiac conduction" EXACT [GOC:mah] is_a: GO:0007267 ! cell-cell signaling is_a: GO:0086065 ! cell communication involved in cardiac conduction intersection_of: GO:0007267 ! cell-cell signaling intersection_of: part_of GO:0061337 ! cardiac conduction created_by: dph creation_date: 2011-11-16T03:43:52Z [Term] id: GO:0086027 name: AV node cell to bundle of His cell signaling namespace: biological_process def: "Any process that mediates the transfer of information from an AV node cardiac muscle cell to a bundle of His cardiomyocyte." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "atrioventricular node to bundle of His cell signaling" EXACT [] synonym: "AV node cell to bundle of His cell signalling" EXACT [GOC:mah] is_a: GO:0086019 ! cell-cell signaling involved in cardiac conduction is_a: GO:0086067 ! AV node cell to bundle of His cell communication created_by: tb creation_date: 2011-11-11T02:02:14Z [Term] id: GO:0086029 name: Purkinje myocyte to ventricular cardiac muscle cell signaling namespace: biological_process def: "Any process that mediates the transfer of information from a Purkinje myocyte to a ventricular cardiac muscle cell." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "Purkinje myocyte to ventricular cardiac muscle cell signalling" EXACT [GOC:mah] is_a: GO:0086019 ! cell-cell signaling involved in cardiac conduction is_a: GO:0086068 ! Purkinje myocyte to ventricular cardiac muscle cell communication intersection_of: GO:0007267 ! cell-cell signaling intersection_of: has_end_location CL:2000046 ! ventricular cardiac muscle cell intersection_of: has_start_location CL:0002068 ! Purkinje myocyte relationship: has_end_location CL:2000046 ! ventricular cardiac muscle cell relationship: has_start_location CL:0002068 ! Purkinje myocyte created_by: tb creation_date: 2011-11-11T02:02:14Z [Term] id: GO:0086065 name: cell communication involved in cardiac conduction namespace: biological_process def: "Any process that mediates interactions between a cell and its surroundings that contributes to the process of cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] is_a: GO:0007154 ! cell communication intersection_of: GO:0007154 ! cell communication intersection_of: part_of GO:0061337 ! cardiac conduction relationship: part_of GO:0061337 ! cardiac conduction created_by: dph creation_date: 2011-11-22T08:57:02Z [Term] id: GO:0086067 name: AV node cell to bundle of His cell communication namespace: biological_process def: "The process that mediates interactions between an AV node cell and its surroundings that contributes to the process of the AV node cell communicating with a bundle of His cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "atrioventricular node cell to bundle of His cell communication" EXACT [] is_a: GO:0086065 ! cell communication involved in cardiac conduction created_by: dph creation_date: 2011-11-22T09:11:44Z [Term] id: GO:0086068 name: Purkinje myocyte to ventricular cardiac muscle cell communication namespace: biological_process def: "The process that mediates interactions between a Purkinje myocyte and its surroundings that contributes to the process of the Purkinje myocyte communicating with a ventricular cardiac muscle cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] is_a: GO:0086065 ! cell communication involved in cardiac conduction created_by: dph creation_date: 2011-11-22T09:14:49Z [Term] id: GO:0086070 name: SA node cell to atrial cardiac muscle cell communication namespace: biological_process def: "The process that mediates interactions between an SA node cardiomyocyte and its surroundings that contributes to the process of the SA node cardiomyocyte communicating with an atrial cardiomyocyte in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "SA node cardiac muscle cell to atrial cardiac muscle cell communication" EXACT [] synonym: "SA node cardiomyocyte to atrial cardiomyocyte communication" EXACT [] synonym: "SAN cardiomyocyte to atrial cardiomyocyte communication" EXACT [] synonym: "sinoatrial node cardiomyocyte to atrial cardiomyocyte communication" EXACT [] synonym: "sinus node cardiomyocyte to atrial cardiomyocyte communication" NARROW [] is_a: GO:0086065 ! cell communication involved in cardiac conduction created_by: dph creation_date: 2011-11-22T09:32:45Z [Term] id: GO:0090009 name: primitive streak formation namespace: biological_process def: "The developmental process pertaining to the initial formation of the primitive streak from unspecified parts. The primitive streak is a ridge of cells running along the midline of the embryo where the mesoderm ingresses. It defines the anterior-posterior axis." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0004341 ! primitive streak relationship: part_of GO:0001702 ! gastrulation with mouth forming second relationship: part_of GO:0009948 ! anterior/posterior axis specification relationship: results_in_formation_of_anatomical_entity UBERON:0004341 ! primitive streak created_by: tb creation_date: 2009-07-29T10:31:31Z [Term] id: GO:0090063 name: positive regulation of microtubule nucleation namespace: biological_process def: "Any process that increases the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell." [GOC:dph, GOC:tb] is_a: GO:0010968 ! regulation of microtubule nucleation is_a: GO:0031116 ! positive regulation of microtubule polymerization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007020 ! microtubule nucleation relationship: positively_regulates GO:0007020 ! microtubule nucleation created_by: tb creation_date: 2009-08-12T11:33:09Z [Term] id: GO:0090068 name: positive regulation of cell cycle process namespace: biological_process def: "Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events." [GOC:dph, GOC:tb] is_a: GO:0010564 ! regulation of cell cycle process is_a: GO:0045787 ! positive regulation of cell cycle intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0022402 ! cell cycle process relationship: positively_regulates GO:0022402 ! cell cycle process created_by: tb creation_date: 2009-09-09T11:39:52Z [Term] id: GO:0090069 name: regulation of ribosome biogenesis namespace: biological_process def: "Any process that modulates the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits." [GOC:dph, GOC:tb] is_a: GO:0044087 ! regulation of cellular component biogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0042254 ! ribosome biogenesis relationship: regulates GO:0042254 ! ribosome biogenesis created_by: tb creation_date: 2009-09-11T10:32:17Z [Term] id: GO:0090070 name: positive regulation of ribosome biogenesis namespace: biological_process def: "Any process that increases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits." [GOC:dph, GOC:tb] is_a: GO:0044089 ! positive regulation of cellular component biogenesis is_a: GO:0090069 ! regulation of ribosome biogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0042254 ! ribosome biogenesis relationship: positively_regulates GO:0042254 ! ribosome biogenesis created_by: tb creation_date: 2009-09-11T10:32:17Z [Term] id: GO:0090071 name: negative regulation of ribosome biogenesis namespace: biological_process def: "Any process that decreases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits." [GOC:dph, GOC:tb] is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:0090069 ! regulation of ribosome biogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0042254 ! ribosome biogenesis relationship: negatively_regulates GO:0042254 ! ribosome biogenesis created_by: tb creation_date: 2009-09-11T10:32:17Z [Term] id: GO:0090087 name: regulation of peptide transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:tb] is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0015833 ! peptide transport relationship: regulates GO:0015833 ! peptide transport created_by: tb creation_date: 2009-10-23T11:21:38Z [Term] id: GO:0090091 name: positive regulation of extracellular matrix disassembly namespace: biological_process def: "Any process that increases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix." [GOC:dph, GOC:tb] is_a: GO:0010715 ! regulation of extracellular matrix disassembly is_a: GO:1903055 ! positive regulation of extracellular matrix organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0022617 ! extracellular matrix disassembly relationship: positively_regulates GO:0022617 ! extracellular matrix disassembly created_by: tb creation_date: 2009-11-04T10:03:25Z [Term] id: GO:0090130 name: tissue migration namespace: biological_process def: "The process in which the population of cells that make up a tissue undergo directed movement." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0032501 ! multicellular organismal process created_by: tb creation_date: 2009-12-07T03:13:55Z [Term] id: GO:0090132 name: epithelium migration namespace: biological_process def: "The process in which the population of cells that make up an epithelium undergo directed movement." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0090130 ! tissue migration created_by: tb creation_date: 2009-12-07T03:19:34Z [Term] id: GO:0090138 name: regulation of actin cytoskeleton organization by cell-cell adhesion namespace: biological_process def: "Any cell-cell adhesion process that modulates the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins." [GOC:ascb_2009, GOC:dph, GOC:tb] synonym: "regulation of actin cytoskeleton organisation by cell-cell adhesion" EXACT [GOC:mah] is_a: GO:0032956 ! regulation of actin cytoskeleton organization is_a: GO:0098609 ! cell-cell adhesion intersection_of: GO:0098609 ! cell-cell adhesion intersection_of: regulates GO:0030036 ! actin cytoskeleton organization created_by: tb creation_date: 2009-12-08T02:05:00Z [Term] id: GO:0090150 name: establishment of protein localization to membrane namespace: biological_process def: "The directed movement of a protein to a specific location in a membrane." [GOC:ascb_2009, GOC:dph, GOC:tb] synonym: "establishment of protein localisation in membrane" EXACT [GOC:mah] synonym: "establishment of protein localization in membrane" EXACT [] is_a: GO:0045184 ! establishment of protein localization is_a: GO:0051668 ! localization within membrane intersection_of: GO:0045184 ! establishment of protein localization intersection_of: has_target_end_location GO:0016020 ! membrane created_by: tb creation_date: 2009-12-08T03:18:51Z [Term] id: GO:0090162 name: establishment of epithelial cell polarity namespace: biological_process def: "The specification and formation of anisotropic intracellular organization of an epithelial cell." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0030010 ! establishment of cell polarity intersection_of: GO:0030010 ! establishment of cell polarity intersection_of: occurs_in CL:0000066 ! epithelial cell relationship: occurs_in CL:0000066 ! epithelial cell created_by: tb creation_date: 2009-12-08T08:58:27Z [Term] id: GO:0090166 name: Golgi disassembly namespace: biological_process def: "A cellular process that results in the breakdown of a Golgi apparatus that contributes to Golgi inheritance." [GOC:ascb_2009, GOC:dph, GOC:tb] synonym: "Golgi apparatus disassembly" EXACT [] is_a: GO:0007030 ! Golgi organization is_a: GO:1903008 ! organelle disassembly intersection_of: GO:0022411 ! cellular component disassembly intersection_of: results_in_disassembly_of GO:0005794 ! Golgi apparatus relationship: part_of GO:0048313 ! Golgi inheritance relationship: results_in_disassembly_of GO:0005794 ! Golgi apparatus created_by: tb creation_date: 2009-12-08T09:15:11Z [Term] id: GO:0090168 name: Golgi reassembly namespace: biological_process def: "The reformation of the Golgi following its breakdown and partitioning contributing to Golgi inheritance." [GOC:ascb_2009, GOC:dph, GOC:tb] synonym: "Golgi apparatus reassembly" EXACT [] is_a: GO:0007030 ! Golgi organization is_a: GO:0022607 ! cellular component assembly relationship: part_of GO:0048313 ! Golgi inheritance created_by: tb creation_date: 2009-12-08T09:15:11Z [Term] id: GO:0090170 name: regulation of Golgi inheritance namespace: biological_process def: "Any process that modulates the rate, frequency or extent of Golgi inheritance. Golgi inheritance is the partitioning of Golgi apparatus between daughter cells at cell division." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:1903358 ! regulation of Golgi organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048313 ! Golgi inheritance relationship: regulates GO:0048313 ! Golgi inheritance created_by: tb creation_date: 2009-12-11T10:21:59Z [Term] id: GO:0090171 name: chondrocyte morphogenesis namespace: biological_process def: "The process in which the structures of a chondrocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a chondrocyte." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0000902 ! cell morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_maturation_of CL:0000138 ! chondrocyte relationship: part_of GO:0002063 ! chondrocyte development relationship: results_in_maturation_of CL:0000138 ! chondrocyte created_by: tb creation_date: 2009-12-11T10:36:02Z [Term] id: GO:0090174 name: organelle membrane fusion namespace: biological_process def: "The joining of two lipid bilayers to form a single organelle membrane." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0048284 ! organelle fusion is_a: GO:0061025 ! membrane fusion intersection_of: GO:0061025 ! membrane fusion intersection_of: results_in_fusion_of GO:0031090 ! organelle membrane relationship: results_in_fusion_of GO:0031090 ! organelle membrane created_by: tb creation_date: 2009-12-11T11:44:58Z [Term] id: GO:0090183 name: regulation of kidney development namespace: biological_process def: "Any process that modulates the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:dph, GOC:tb, GOC:yaf] synonym: "regulation of nephrogenesis" RELATED [GOC:dph, GOC:tb] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001822 ! kidney development relationship: regulates GO:0001822 ! kidney development created_by: tb creation_date: 2009-12-18T10:50:56Z [Term] id: GO:0090184 name: positive regulation of kidney development namespace: biological_process def: "Any process that increases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:dph, GOC:tb, GOC:yaf] synonym: "positive regulation of nephrogenesis" RELATED [GOC:dph, GOC:tb] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:0090183 ! regulation of kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001822 ! kidney development relationship: positively_regulates GO:0001822 ! kidney development created_by: tb creation_date: 2009-12-18T10:52:01Z [Term] id: GO:0090185 name: negative regulation of kidney development namespace: biological_process def: "Any process that decreases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:dph, GOC:tb, GOC:yaf] synonym: "negative regulation of nephrogenesis" RELATED [GOC:dph, GOC:tb] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:0090183 ! regulation of kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001822 ! kidney development relationship: negatively_regulates GO:0001822 ! kidney development created_by: tb creation_date: 2009-12-18T10:58:45Z [Term] id: GO:0090189 name: regulation of branching involved in ureteric bud morphogenesis namespace: biological_process def: "Any process that modulates the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules." [GOC:dph, GOC:tb, GOC:yaf] is_a: GO:0060688 ! regulation of morphogenesis of a branching structure is_a: GO:0090183 ! regulation of kidney development is_a: GO:1905330 ! regulation of morphogenesis of an epithelium is_a: GO:2000027 ! regulation of animal organ morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001658 ! branching involved in ureteric bud morphogenesis relationship: regulates GO:0001658 ! branching involved in ureteric bud morphogenesis created_by: tb creation_date: 2009-12-18T11:11:17Z [Term] id: GO:0090190 name: positive regulation of branching involved in ureteric bud morphogenesis namespace: biological_process def: "Any process that increases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules." [GOC:dph, GOC:tb, GOC:yaf] is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:0090189 ! regulation of branching involved in ureteric bud morphogenesis is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001658 ! branching involved in ureteric bud morphogenesis relationship: positively_regulates GO:0001658 ! branching involved in ureteric bud morphogenesis created_by: tb creation_date: 2009-12-18T11:11:17Z [Term] id: GO:0090191 name: negative regulation of branching involved in ureteric bud morphogenesis namespace: biological_process def: "Any process that decreases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules." [GOC:dph, GOC:tb, GOC:yaf] is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:0090189 ! regulation of branching involved in ureteric bud morphogenesis is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001658 ! branching involved in ureteric bud morphogenesis relationship: negatively_regulates GO:0001658 ! branching involved in ureteric bud morphogenesis created_by: tb creation_date: 2009-12-18T11:11:17Z [Term] id: GO:0090257 name: regulation of muscle system process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a muscle system process, a multicellular organismal process carried out by any of the organs or tissues in a muscle system." [GOC:dph, GOC:tb] is_a: GO:0044057 ! regulation of system process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003012 ! muscle system process relationship: regulates GO:0003012 ! muscle system process created_by: tb creation_date: 2010-02-03T11:48:13Z [Term] id: GO:0090273 name: regulation of somatostatin secretion namespace: biological_process def: "Any process that modulates the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas." [GOC:BHF] is_a: GO:0090276 ! regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0070253 ! somatostatin secretion relationship: regulates GO:0070253 ! somatostatin secretion created_by: tb creation_date: 2010-02-05T02:54:14Z [Term] id: GO:0090274 name: positive regulation of somatostatin secretion namespace: biological_process def: "Any process that increases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas." [GOC:BHF] is_a: GO:0090273 ! regulation of somatostatin secretion is_a: GO:0090277 ! positive regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0070253 ! somatostatin secretion relationship: positively_regulates GO:0070253 ! somatostatin secretion created_by: tb creation_date: 2010-02-05T02:54:14Z [Term] id: GO:0090275 name: negative regulation of somatostatin secretion namespace: biological_process def: "Any process that decreases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas." [GOC:BHF] is_a: GO:0090273 ! regulation of somatostatin secretion is_a: GO:0090278 ! negative regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0070253 ! somatostatin secretion relationship: negatively_regulates GO:0070253 ! somatostatin secretion created_by: tb creation_date: 2010-02-05T02:54:14Z [Term] id: GO:0090276 name: regulation of peptide hormone secretion namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules." [GOC:tb] is_a: GO:0002791 ! regulation of peptide secretion is_a: GO:0046883 ! regulation of hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030072 ! peptide hormone secretion relationship: regulates GO:0030072 ! peptide hormone secretion created_by: tb creation_date: 2010-02-05T02:56:39Z [Term] id: GO:0090277 name: positive regulation of peptide hormone secretion namespace: biological_process def: "Any process that increases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules." [GOC:tb] is_a: GO:0002793 ! positive regulation of peptide secretion is_a: GO:0046887 ! positive regulation of hormone secretion is_a: GO:0090276 ! regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030072 ! peptide hormone secretion relationship: positively_regulates GO:0030072 ! peptide hormone secretion created_by: tb creation_date: 2010-02-05T02:56:39Z [Term] id: GO:0090278 name: negative regulation of peptide hormone secretion namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules." [GOC:tb] is_a: GO:0002792 ! negative regulation of peptide secretion is_a: GO:0046888 ! negative regulation of hormone secretion is_a: GO:0090276 ! regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030072 ! peptide hormone secretion relationship: negatively_regulates GO:0030072 ! peptide hormone secretion created_by: tb creation_date: 2010-02-05T02:56:39Z [Term] id: GO:0090299 name: regulation of neural crest formation namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds." [GOC:tb] is_a: GO:0010717 ! regulation of epithelial to mesenchymal transition is_a: GO:0022603 ! regulation of anatomical structure morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0014029 ! neural crest formation relationship: regulates GO:0014029 ! neural crest formation created_by: tb creation_date: 2010-03-12T04:08:26Z [Term] id: GO:0090300 name: positive regulation of neural crest formation namespace: biological_process def: "Any process that increases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes." [GOC:tb] is_a: GO:0010718 ! positive regulation of epithelial to mesenchymal transition is_a: GO:0090299 ! regulation of neural crest formation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0014029 ! neural crest formation relationship: positively_regulates GO:0014029 ! neural crest formation created_by: tb creation_date: 2010-03-12T04:08:26Z [Term] id: GO:0090301 name: negative regulation of neural crest formation namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes." [GOC:tb] is_a: GO:0010719 ! negative regulation of epithelial to mesenchymal transition is_a: GO:0090299 ! regulation of neural crest formation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0014029 ! neural crest formation relationship: negatively_regulates GO:0014029 ! neural crest formation created_by: tb creation_date: 2010-03-12T04:08:26Z [Term] id: GO:0090304 name: nucleic acid metabolic process namespace: biological_process def: "Any cellular metabolic process involving nucleic acids." [GOC:dph, GOC:tb] is_a: GO:0006139 ! nucleobase-containing compound metabolic process is_a: GO:0043170 ! macromolecule metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:33696 ! nucleic acid relationship: has_primary_input_or_output CHEBI:33696 ! nucleic acid property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26133" xsd:anyURI created_by: tb creation_date: 2010-04-07T10:18:47Z [Term] id: GO:0090316 name: positive regulation of intracellular protein transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells." [GOC:tb] is_a: GO:0032388 ! positive regulation of intracellular transport is_a: GO:0033157 ! regulation of intracellular protein transport is_a: GO:0051222 ! positive regulation of protein transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006886 ! intracellular protein transport relationship: positively_regulates GO:0006886 ! intracellular protein transport created_by: tb creation_date: 2010-04-16T03:45:07Z [Term] id: GO:0090317 name: negative regulation of intracellular protein transport namespace: biological_process def: "Any process that decreases the frequency, rate or extent of the directed movement of proteins within cells." [GOC:tb] is_a: GO:0032387 ! negative regulation of intracellular transport is_a: GO:0033157 ! regulation of intracellular protein transport is_a: GO:0051224 ! negative regulation of protein transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006886 ! intracellular protein transport relationship: negatively_regulates GO:0006886 ! intracellular protein transport created_by: tb creation_date: 2010-04-16T03:45:07Z [Term] id: GO:0090325 name: regulation of locomotion involved in locomotory behavior namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement." [GOC:dph, GOC:kmv, GOC:tb] is_a: GO:0040012 ! regulation of locomotion is_a: GO:0050795 ! regulation of behavior intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0031987 ! locomotion involved in locomotory behavior relationship: regulates GO:0031987 ! locomotion involved in locomotory behavior created_by: tb creation_date: 2010-05-14T10:24:29Z [Term] id: GO:0090326 name: positive regulation of locomotion involved in locomotory behavior namespace: biological_process def: "Any process that increases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement." [GOC:dph, GOC:kmv, GOC:tb] is_a: GO:0040017 ! positive regulation of locomotion is_a: GO:0048520 ! positive regulation of behavior is_a: GO:0090325 ! regulation of locomotion involved in locomotory behavior intersection_of: GO:0050789 ! regulation of biological process intersection_of: positively_regulates GO:0031987 ! locomotion involved in locomotory behavior relationship: positively_regulates GO:0031987 ! locomotion involved in locomotory behavior created_by: tb creation_date: 2010-05-14T10:26:58Z [Term] id: GO:0090327 name: negative regulation of locomotion involved in locomotory behavior namespace: biological_process def: "Any process that decreases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement." [GOC:dph, GOC:kmv, GOC:tb] is_a: GO:0040013 ! negative regulation of locomotion is_a: GO:0048521 ! negative regulation of behavior is_a: GO:0090325 ! regulation of locomotion involved in locomotory behavior intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0031987 ! locomotion involved in locomotory behavior relationship: negatively_regulates GO:0031987 ! locomotion involved in locomotory behavior created_by: tb creation_date: 2010-05-14T10:26:58Z [Term] id: GO:0090425 name: acinar cell differentiation namespace: biological_process def: "The epithelial cell differentiation process in which a relatively unspecialized cell acquires specialized features of an acinar cell, a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini." [GOC:dph, GOC:tb] is_a: GO:0002067 ! glandular epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000622 ! acinar cell relationship: results_in_acquisition_of_features_of CL:0000622 ! acinar cell created_by: tb creation_date: 2012-05-04T09:24:48Z [Term] id: GO:0090435 name: protein localization to nuclear envelope namespace: biological_process def: "A process in which a protein is transported to, or maintained at, a location within a nuclear envelope." [GOC:tb] synonym: "protein localization in nuclear envelope" EXACT [] is_a: GO:0034504 ! protein localization to nucleus intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0005635 ! nuclear envelope relationship: has_target_end_location GO:0005635 ! nuclear envelope created_by: tb creation_date: 2012-07-30T01:50:41Z [Term] id: GO:0090493 name: catecholamine uptake namespace: biological_process def: "The directed movement of catecholamine into a cell." [GOC:dph, GOC:tb] is_a: GO:0051937 ! catecholamine transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:33567 ! catecholamine intersection_of: has_target_end_location GO:0005622 ! intracellular anatomical structure intersection_of: has_target_start_location GO:0005576 ! extracellular region relationship: has_target_end_location GO:0005622 ! intracellular anatomical structure relationship: has_target_start_location GO:0005576 ! extracellular region created_by: tb creation_date: 2012-10-17T11:06:17Z [Term] id: GO:0090497 name: mesenchymal cell migration namespace: biological_process def: "The orderly movement of a mesenchymal cell from one site to another, often during the development of a multicellular organism." [GOC:dph, GOC:tb] is_a: GO:0001667 ! ameboidal-type cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0008019 ! mesenchymal cell relationship: results_in_movement_of CL:0008019 ! mesenchymal cell created_by: tb creation_date: 2012-10-17T12:08:17Z [Term] id: GO:0090596 name: sensory organ morphogenesis namespace: biological_process def: "Morphogenesis of a sensory organ. A sensory organ is defined as a tissue or set of tissues that work together to receive and transmit signals from external or internal stimuli. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." [GOC:kmv, ISBN:978-0199210893] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000020 ! sense organ relationship: part_of GO:0007423 ! sensory organ development relationship: results_in_morphogenesis_of UBERON:0000020 ! sense organ created_by: tb creation_date: 2014-08-22T13:23:20Z [Term] id: GO:0090598 name: male anatomical structure morphogenesis namespace: biological_process def: "The processes by which anatomical structures that are only present in the male organism are generated and organized." [GOC:kmv, GOC:tb] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0014403 ! male anatomical structure relationship: part_of GO:0046661 ! male sex differentiation relationship: results_in_morphogenesis_of UBERON:0014403 ! male anatomical structure created_by: tb creation_date: 2014-08-22T13:29:45Z [Term] id: GO:0090685 name: RNA localization to nucleus namespace: biological_process def: "A macromolecular localization process in which RNA is transported to and maintained in a location within the nucleus." [GOC:mah, PMID:26305931] synonym: "RNA localisation to nucleus" EXACT [GOC:mah] is_a: GO:0006403 ! RNA localization intersection_of: GO:0006403 ! RNA localization intersection_of: has_target_end_location GO:0005634 ! nucleus relationship: has_target_end_location GO:0005634 ! nucleus created_by: tb creation_date: 2016-07-19T17:00:49Z [Term] id: GO:0090741 name: pigment granule membrane namespace: cellular_component def: "Any membrane that is part of a pigment granule." [PMID:11294610] is_a: GO:0030659 ! cytoplasmic vesicle membrane is_a: GO:0098588 ! bounding membrane of organelle intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0048770 ! pigment granule relationship: bounding_layer_of GO:0048770 ! pigment granule relationship: part_of GO:0048770 ! pigment granule created_by: tb creation_date: 2017-05-16T22:33:39Z [Term] id: GO:0097014 name: ciliary plasm namespace: cellular_component def: "All of the contents of a cilium, excluding the plasma membrane surrounding the cilium." [GOC:BHF, GOC:cilia, GOC:dos, PMID:17895364] comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. Also, researchers consider the composition of both the plasm and the membrane of the cilium to be detectably different from that in the non-ciliary cytosol and plasma membrane (e.g. in terms of calcium ion concentration, membrane lipid composition, and more). For this reason, the term "ciliary plasm" is not linked to "cytoplasm". synonym: "cilial cytoplasm" RELATED [] synonym: "ciliary cytoplasm" RELATED [] synonym: "cilium cytoplasm" RELATED [] synonym: "cilium plasm" EXACT [] synonym: "microtubule-based flagellar cytoplasm" RELATED [] synonym: "microtubule-based flagellar matrix" NARROW [] synonym: "microtubule-based flagellum cytoplasm" RELATED [] synonym: "microtubule-based flagellum matrix" NARROW [] is_a: GO:0032838 ! plasma membrane bounded cell projection cytoplasm intersection_of: GO:0005737 ! cytoplasm intersection_of: part_of GO:0005929 ! cilium relationship: part_of GO:0005929 ! cilium created_by: pr creation_date: 2011-03-23T01:52:31Z [Term] id: GO:0097026 name: dendritic cell dendrite assembly namespace: biological_process def: "Formation of dendrites, branched cellular projections (or cytoplasmic extension) that are extended from the surface of a dendritic immune cell, and which enable the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells." [CL:0000451, GOC:BHF, PMID:12200351] comment: Note that dendrites of dendritic cells should not be confused with neuronal cell dendrites, which process electrical signals. synonym: "dendritic extension" BROAD [] is_a: GO:0120031 ! plasma membrane bounded cell projection assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0097511 ! dendritic cell dendrite relationship: results_in_assembly_of GO:0097511 ! dendritic cell dendrite created_by: pr creation_date: 2011-03-31T04:52:53Z [Term] id: GO:0097028 name: dendritic cell differentiation namespace: biological_process def: "The process in which a precursor cell type acquires the specialized features of a dendritic cell. A dendritic cell is a leukocyte of dendritic lineage specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation." [CL:0000451, GOC:pr] comment: Note that immunologists typically use the word 'maturation' to refer to dendritic cells undergoing the process that GO describes as 'cell differentiation'. is_a: GO:1903131 ! mononuclear cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000451 ! dendritic cell relationship: results_in_acquisition_of_features_of CL:0000451 ! dendritic cell created_by: pr creation_date: 2011-04-01T10:08:42Z [Term] id: GO:0097048 name: dendritic cell apoptotic process namespace: biological_process def: "Any apoptotic process in a dendritic cell, a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation." [CL:0000451, GOC:BHF, GOC:mtg_apoptosis, PMID:15059845] synonym: "dendritic cell apoptosis" NARROW [] is_a: GO:0071887 ! leukocyte apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000451 ! dendritic cell relationship: occurs_in CL:0000451 ! dendritic cell created_by: pr creation_date: 2011-05-04T02:18:59Z [Term] id: GO:0097049 name: motor neuron apoptotic process namespace: biological_process def: "Any apoptotic process in a motor neuron, an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement." [CL:0000100, GOC:BHF, GOC:mtg_apoptosis, PMID:14523086] synonym: "motoneuron apoptosis" EXACT [] synonym: "motor neuron apoptosis" NARROW [] is_a: GO:0051402 ! neuron apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000100 ! motor neuron relationship: occurs_in CL:0000100 ! motor neuron created_by: pr creation_date: 2011-05-04T02:21:43Z [Term] id: GO:0097050 name: type B pancreatic cell apoptotic process namespace: biological_process def: "Any apoptotic process in a type B pancreatic cell, a cell located towards center of the islets of Langerhans that secretes insulin." [CL:0000169, GOC:BHF, GOC:mtg_apoptosis, PMID:16087305] synonym: "pancreatic B cell apoptosis" EXACT [] synonym: "pancreatic beta cell apoptosis" EXACT [] synonym: "type B pancreatic cell apoptosis" NARROW [] is_a: GO:1904019 ! epithelial cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000169 ! type B pancreatic cell relationship: occurs_in CL:0000169 ! type B pancreatic cell created_by: pr creation_date: 2011-05-04T02:24:38Z [Term] id: GO:0097060 name: synaptic membrane namespace: cellular_component def: "A specialized area of membrane on either the presynaptic or the postsynaptic side of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell." [GOC:BHF, PMID:20410104] subset: goslim_synapse is_a: GO:0098590 ! plasma membrane region intersection_of: GO:0098590 ! plasma membrane region intersection_of: part_of GO:0045202 ! synapse relationship: part_of GO:0045202 ! synapse created_by: pr creation_date: 2011-06-07T11:22:09Z [Term] id: GO:0097084 name: vascular associated smooth muscle cell development namespace: biological_process def: "The process aimed at the progression of a vascular smooth muscle cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels." [GOC:BHF] synonym: "vascular smooth muscle cell development" EXACT [] is_a: GO:0055001 ! muscle cell development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of CL:0000359 ! vascular associated smooth muscle cell relationship: part_of GO:0035886 ! vascular associated smooth muscle cell differentiation relationship: results_in_development_of CL:0000359 ! vascular associated smooth muscle cell created_by: pr creation_date: 2011-06-20T04:03:08Z [Term] id: GO:0097152 name: mesenchymal cell apoptotic process namespace: biological_process def: "Any apoptotic process in a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types." [CL:0000134, GOC:mtg_apoptosis, GOC:yaf, PMID:18231833] synonym: "mesenchymal cell apoptosis" NARROW [] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0008019 ! mesenchymal cell relationship: occurs_in CL:0008019 ! mesenchymal cell created_by: pr creation_date: 2011-09-06T02:31:59Z [Term] id: GO:0097164 name: ammonium ion metabolic process namespace: biological_process def: "The chemical reactions and pathways involving the ammonium ion." [GOC:dhl, GOC:tb, PMID:14671018] synonym: "ammonium ion metabolism" EXACT [] synonym: "ammonium metabolic process" RELATED [] is_a: GO:0006807 ! nitrogen compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:28938 ! ammonium relationship: has_primary_input_or_output CHEBI:28938 ! ammonium created_by: pr creation_date: 2011-09-28T04:21:30Z [Term] id: GO:0097190 name: apoptotic signaling pathway namespace: biological_process alt_id: GO:0008624 def: "The series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered." [GOC:mtg_apoptosis] comment: This term can be used to annotate gene products involved in apoptotic events happening downstream of the cross-talk point between the extrinsic and intrinsic apoptotic pathways. The cross-talk starts when caspase-8 cleaves Bid and truncated Bid interacts with mitochondria. From this point on it is not possible to distinguish between extrinsic and intrinsic pathways. synonym: "apoptotic signalling pathway" EXACT [GOC:mah] synonym: "induction of apoptosis by extracellular signals" EXACT [] is_a: GO:0007165 ! signal transduction relationship: part_of GO:0006915 ! apoptotic process created_by: pr creation_date: 2011-11-23T09:30:23Z [Term] id: GO:0097194 name: execution phase of apoptosis namespace: biological_process def: "A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died." [GOC:mtg_apoptosis, PMID:21760595] synonym: "apoptosis" NARROW [] synonym: "execution phase of apoptotic process" EXACT [] is_a: GO:0009987 ! cellular process relationship: has_part GO:0032060 ! bleb assembly relationship: part_of GO:0006915 ! apoptotic process created_by: pr creation_date: 2011-11-23T09:45:24Z [Term] id: GO:0097237 name: cellular response to toxic substance namespace: biological_process def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus." [GOC:pr] created_by: pr creation_date: 2012-02-02T12:23:31Z [Term] id: GO:0097254 name: renal tubular secretion namespace: biological_process def: "The elimination of substances from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine. Substances that are secreted include organic anions, ammonia, potassium and drugs." [GOC:rph, PMID:25287933, Wikipedia:Renal_secretion#Secretion] is_a: GO:0003014 ! renal system process is_a: GO:0007588 ! excretion property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22368" xsd:anyURI created_by: pr creation_date: 2012-03-05T02:03:58Z [Term] id: GO:0097284 name: hepatocyte apoptotic process namespace: biological_process def: "Any apoptotic process in a hepatocyte, the main structural component of the liver." [CL:0000182, GOC:jc, GOC:mtg_apoptosis, PMID:15856020] synonym: "hepatocyte apoptosis" NARROW [] is_a: GO:1904019 ! epithelial cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000182 ! hepatocyte relationship: occurs_in CL:0000182 ! hepatocyte created_by: pr creation_date: 2012-03-29T10:23:21Z [Term] id: GO:0097355 name: protein localization to heterochromatin namespace: biological_process def: "Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into heterochromatin." [GOC:mah] synonym: "protein localisation to heterochromatin" EXACT [GOC:mah] is_a: GO:0071168 ! protein localization to chromatin intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0000792 ! heterochromatin relationship: has_target_end_location GO:0000792 ! heterochromatin created_by: pr creation_date: 2012-07-03T03:19:07Z [Term] id: GO:0097360 name: chorionic trophoblast cell proliferation namespace: biological_process def: "The multiplication or reproduction of chorionic trophoblast cells, resulting in the expansion of their population." [CL:0011101, GOC:BHF, PMID:15150278] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0011101 ! chorionic trophoblast cell relationship: acts_on_population_of CL:0011101 ! chorionic trophoblast cell created_by: pr creation_date: 2012-07-19T10:17:37Z [Term] id: GO:0097386 name: glial cell projection namespace: cellular_component def: "A prolongation or process extending from a glial cell." [GOC:mc] synonym: "glial process" RELATED [] synonym: "glial projection" RELATED [] is_a: GO:0120025 ! plasma membrane bounded cell projection is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: GO:0120025 ! plasma membrane bounded cell projection intersection_of: part_of CL:0000125 ! glial cell relationship: part_of CL:0000125 ! glial cell created_by: pr creation_date: 2012-10-22T13:55:54Z [Term] id: GO:0097402 name: neuroblast migration namespace: biological_process def: "The orderly movement of a neuroblast from one site to another, often during the development of a multicellular organism or multicellular structure. A neuroblast is any cell that will divide and give rise to a neuron." [CL:0000031, GOC:jc, PMID:15543145] is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000031 ! neuroblast (sensu Vertebrata) relationship: results_in_movement_of CL:0000031 ! neuroblast (sensu Vertebrata) created_by: pr creation_date: 2012-10-29T08:24:37Z [Term] id: GO:0097427 name: microtubule bundle namespace: cellular_component def: "An arrangement of closely apposed microtubules running parallel to each other." [NIF_Subcellular:sao1872343973] synonym: "microtubule fascicle" EXACT [] xref: NIF_Subcellular:sao1872343973 is_a: GO:0110165 ! cellular anatomical entity relationship: has_part GO:0005874 ! microtubule relationship: part_of GO:0005856 ! cytoskeleton created_by: pr creation_date: 2012-11-07T15:01:27Z [Term] id: GO:0097435 name: supramolecular fiber organization namespace: biological_process alt_id: GO:0043206 def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a supramolecular fiber, a polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure." [GOC:pr] synonym: "extracellular fibril organisation" NARROW [] synonym: "extracellular fibril organization" NARROW [] synonym: "extracellular fibril organization and biogenesis" NARROW [GOC:mah] synonym: "fibril organisation" RELATED [] synonym: "fibril organization" RELATED [] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0099512 ! supramolecular fiber relationship: results_in_organization_of GO:0099512 ! supramolecular fiber created_by: pr creation_date: 2012-11-27T15:46:25Z [Term] id: GO:0097473 name: retinal rod cell apoptotic process namespace: biological_process def: "Any apoptotic process in a retinal rod cell, one of the two photoreceptor cell types of the vertebrate retina." [CL:0000604, GOC:jc, PMID:17202487] synonym: "rod photoreceptor apoptotic process" EXACT [] is_a: GO:0051402 ! neuron apoptotic process is_a: GO:1990009 ! retinal cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000604 ! retinal rod cell relationship: occurs_in CL:0000604 ! retinal rod cell created_by: pr creation_date: 2013-03-21T09:44:45Z [Term] id: GO:0097474 name: retinal cone cell apoptotic process namespace: biological_process def: "Any apoptotic process in a retinal cone cell, one of the two photoreceptor cell types of the vertebrate retina." [CL:0000573, GOC:jc] synonym: "cone photoreceptor apoptotic process" EXACT [] is_a: GO:0051402 ! neuron apoptotic process is_a: GO:1990009 ! retinal cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000573 ! retinal cone cell relationship: occurs_in CL:0000573 ! retinal cone cell created_by: pr creation_date: 2013-03-21T09:46:22Z [Term] id: GO:0097475 name: motor neuron migration namespace: biological_process def: "The orderly movement of a motor neuron from one site to another. A motor neuron is an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement." [CL:0000100, GOC:yaf, PMID:20711475] is_a: GO:0001764 ! neuron migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000100 ! motor neuron relationship: results_in_movement_of CL:0000100 ! motor neuron created_by: pr creation_date: 2013-04-23T13:00:46Z [Term] id: GO:0097476 name: spinal cord motor neuron migration namespace: biological_process def: "The orderly movement of a spinal cord motor neuron from one site to another. A spinal cord motor neuron is a motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement." [CL:0011001, GOC:yaf, PMID:20711475] is_a: GO:0097475 ! motor neuron migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0011001 ! spinal cord motor neuron relationship: results_in_movement_of CL:0011001 ! spinal cord motor neuron created_by: pr creation_date: 2013-04-23T13:03:46Z [Term] id: GO:0097511 name: dendritic cell dendrite namespace: cellular_component def: "A branched cellular projection (or cytoplasmic extension) that is extended from the surface of a dendritic immune cell, and which enables the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells." [CL:0000451, GOC:BHF, GOC:cjm, PMID:12200351] is_a: GO:0120025 ! plasma membrane bounded cell projection intersection_of: GO:0120025 ! plasma membrane bounded cell projection intersection_of: part_of CL:0000451 ! dendritic cell relationship: part_of CL:0000451 ! dendritic cell created_by: pr creation_date: 2013-10-16T13:02:25Z [Term] id: GO:0097512 name: cardiac myofibril namespace: cellular_component def: "A cardiac myofibril is a myofibril specific to cardiac muscle cells." [GOC:cjm, GOC:devbiol] is_a: GO:0030016 ! myofibril intersection_of: GO:0030016 ! myofibril intersection_of: part_of CL:0000746 ! cardiac muscle cell relationship: part_of CL:0000746 ! cardiac muscle cell created_by: pr creation_date: 2013-10-16T13:04:58Z [Term] id: GO:0097524 name: sperm plasma membrane namespace: cellular_component def: "A plasma membrane that is part of a sperm cell." [GOC:cjm] is_a: GO:0005886 ! plasma membrane intersection_of: GO:0005886 ! plasma membrane intersection_of: part_of CL:0000019 ! sperm relationship: part_of CL:0000019 ! sperm created_by: pr creation_date: 2013-10-18T11:31:17Z [Term] id: GO:0097529 name: myeloid leukocyte migration namespace: biological_process def: "The movement of a myeloid leukocyte within or between different tissues and organs of the body." [GOC:cvs, PMID:22342843, PMID:24157461] is_a: GO:0050900 ! leukocyte migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000766 ! myeloid leukocyte relationship: results_in_movement_of CL:0000766 ! myeloid leukocyte created_by: pr creation_date: 2013-11-11T13:59:43Z [Term] id: GO:0097534 name: lymphoid lineage cell migration namespace: biological_process def: "The orderly movement of a lymphoid lineage cell from one site to another. A lymphoid lineage cell, also called a lymphoid lineage restricted progenitor cell, is a progenitor cell restricted to the lymphoid lineage." [GOC:pr, PMID:22342843] synonym: "lymphoid lineage restricted progenitor cell migration" EXACT [] is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000838 ! lymphoid lineage restricted progenitor cell relationship: results_in_movement_of CL:0000838 ! lymphoid lineage restricted progenitor cell created_by: pr creation_date: 2013-11-28T10:47:15Z [Term] id: GO:0097576 name: vacuole fusion namespace: biological_process def: "Merging of two or more vacuoles, or of vacuoles and vesicles within a cell to form a single larger vacuole." [GOC:pr, GOC:vw, Wikipedia:Vacuole] is_a: GO:0007033 ! vacuole organization is_a: GO:0048284 ! organelle fusion intersection_of: GO:0009987 ! cellular process intersection_of: results_in_fusion_of GO:0005773 ! vacuole relationship: results_in_fusion_of GO:0005773 ! vacuole created_by: pr creation_date: 2014-02-28T09:49:31Z [Term] id: GO:0097708 name: intracellular vesicle namespace: cellular_component def: "Any vesicle that is part of the intracellular region." [GOC:vesicles] is_a: GO:0031982 ! vesicle is_a: GO:0043231 ! intracellular membrane-bounded organelle intersection_of: GO:0031982 ! vesicle intersection_of: part_of GO:0005622 ! intracellular anatomical structure created_by: pr creation_date: 2016-03-29T17:39:45Z [Term] id: GO:0097711 name: ciliary basal body-plasma membrane docking namespace: biological_process def: "The docking of a cytosolic centriole/basal body to the plasma membrane via the ciliary transition fibers. In some species this may happen via an intermediate step, by first docking to the ciliary vesicle via the ciliary transition fibers. The basal body-ciliary vesicle then relocates to the plasma membrane, followed by the ciliary vesicle fusing with the plasma membrane, effectively attaching the basal body to the plasma membrane." [GOC:cilia, PMID:13978319, PMID:23348840, PMID:23530209, PMID:25686250, PMID:26981235, Reactome:R-HSA-5620912.1] comment: Basal bodies in jawed vertebrates appear to first attach to a ciliary vesicle. It is unclear how specific this is to jawed vertebrates or if other organisms also employ this sequence. Some species like Giardia intestinalis do not relocate their basal bodies to the plasma membrane, but have their axonemes extend through the cytosol to then protrude out of the cell to form flagella. synonym: "anchoring of the basal body to the plasma membrane" RELATED [] synonym: "ciliary basal body docking" EXACT [] xref: Reactome:R-HSA-5620912.1 is_a: GO:0140056 ! organelle localization by membrane tethering relationship: part_of GO:0060271 ! cilium assembly created_by: pr creation_date: 2016-08-05T16:12:33Z [Term] id: GO:0097712 name: vesicle targeting, trans-Golgi to periciliary membrane compartment namespace: biological_process def: "The process in which vesicles formed at the trans-Golgi network are directed to the plasma membrane surrounding the base of the cilium, including the ciliary pocket, mediated by molecules at the vesicle membrane and target membrane surfaces." [GOC:cilia, PMID:20106869, PMID:23351793, PMID:24814148, PMID:26485645, Reactome:R-HSA-5620920.1] is_a: GO:0048199 ! vesicle targeting, to, from or within Golgi relationship: part_of GO:0060271 ! cilium assembly created_by: pr creation_date: 2016-08-05T16:16:28Z [Term] id: GO:0097722 name: sperm motility namespace: biological_process def: "Any process involved in the controlled movement of a sperm cell." [GOC:cilia, GOC:krc] subset: gocheck_do_not_annotate synonym: "sperm movement" EXACT [] is_a: GO:0022414 ! reproductive process is_a: GO:0048870 ! cell motility intersection_of: GO:0048870 ! cell motility intersection_of: results_in_movement_of CL:0000019 ! sperm relationship: results_in_movement_of CL:0000019 ! sperm created_by: pr creation_date: 2016-09-01T12:00:45Z [Term] id: GO:0097734 name: extracellular exosome biogenesis namespace: biological_process def: "The assembly and secretion of an extracellular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane." [GOC:bf, GOC:PARL, PMID:19442504, PMID:25392495] synonym: "exosome assembly or secretion" EXACT [] synonym: "exosome biogenesis" EXACT [] synonym: "exosome production" EXACT [] synonym: "ILV assembly" RELATED [] synonym: "intraluminal vesicle assembly" RELATED [] is_a: GO:0140112 ! extracellular vesicle biogenesis created_by: pr creation_date: 2016-10-03T14:35:25Z [Term] id: GO:0098523 name: neuromuscular junction of myotube namespace: cellular_component def: "A neuromuscular junction in which the target muscle cell is a myotube." [GOC:dos] comment: In vertebrates, the term 'neuromuscular junction' is limited to synapses targeting the myotubes of skeletal muscle (AKA skeletal muscle fibers). Neuromuscular junctions targeting other muscle cell types exist in invertebrates such as the mononucleate somatic muscles of nematodes. is_a: GO:0031594 ! neuromuscular junction intersection_of: GO:0045202 ! synapse intersection_of: overlaps CL:0000100 ! motor neuron intersection_of: overlaps CL:0002372 ! myotube relationship: overlaps CL:0002372 ! myotube created_by: dos creation_date: 2013-10-14T12:05:12Z [Term] id: GO:0098528 name: skeletal muscle fiber differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle fiber cell. Skeletal muscle fiber differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual skeletal muscle fibers fuse to form bigger myotubes and start to contract." [GOC:dos] is_a: GO:0014902 ! myotube differentiation is_a: GO:0035914 ! skeletal muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0008002 ! skeletal muscle fiber relationship: results_in_acquisition_of_features_of CL:0008002 ! skeletal muscle fiber created_by: dos creation_date: 2013-10-15T14:00:34Z [Term] id: GO:0098542 name: defense response to other organism namespace: biological_process alt_id: GO:0009814 def: "Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism." [GOC:dos] subset: goslim_generic subset: goslim_prokaryote synonym: "defence response incompatible interaction" NARROW [] synonym: "defence response to pathogen, incompatible interaction" NARROW [] synonym: "defense response, incompatible interaction" NARROW [] synonym: "resistance response to pathogen" NARROW [] is_a: GO:0006952 ! defense response is_a: GO:0051707 ! response to other organism intersection_of: GO:0006952 ! defense response intersection_of: has_primary_input NCBITaxon_Union:0000030 property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22173" xsd:anyURI created_by: dos creation_date: 2013-11-11T12:59:11Z [Term] id: GO:0098588 name: bounding membrane of organelle namespace: cellular_component def: "The lipid bilayer that forms the outer-most layer of an organelle." [GOC:dos] comment: Examples include the outer membranes of double membrane bound organelles such as mitochondria as well as the bounding membranes of single-membrane bound organelles such as lysosomes. is_a: GO:0031090 ! organelle membrane intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0043226 ! organelle relationship: bounding_layer_of GO:0043226 ! organelle created_by: dos creation_date: 2014-02-26T13:41:31Z [Term] id: GO:0098590 name: plasma membrane region namespace: cellular_component def: "A membrane that is a (regional) part of the plasma membrane." [GOC:dos] comment: Note that this term should not be used for direct manual annotation as it should always be possible to choose a more specific subclass. subset: gocheck_do_not_manually_annotate synonym: "region of plasma membrane" EXACT [] is_a: GO:0016020 ! membrane intersection_of: GO:0016020 ! membrane intersection_of: part_of GO:0005886 ! plasma membrane relationship: part_of GO:0005886 ! plasma membrane created_by: dos creation_date: 2014-03-06T11:55:32Z [Term] id: GO:0098609 name: cell-cell adhesion namespace: biological_process alt_id: GO:0016337 def: "The attachment of one cell to another cell via adhesion molecules." [GOC:dos] synonym: "single organismal cell-cell adhesion" RELATED [] is_a: GO:0007155 ! cell adhesion created_by: dos creation_date: 2014-04-16T13:40:03Z [Term] id: GO:0098635 name: protein complex involved in cell-cell adhesion namespace: cellular_component def: "Any protein complex that is capable of carrying out some part of the process of cell-cell adhesion." [GOC:dos] is_a: GO:0098636 ! protein complex involved in cell adhesion intersection_of: GO:0032991 ! protein-containing complex intersection_of: capable_of_part_of GO:0098609 ! cell-cell adhesion relationship: capable_of_part_of GO:0098609 ! cell-cell adhesion [Term] id: GO:0098636 name: protein complex involved in cell adhesion namespace: cellular_component alt_id: GO:1990307 def: "Any protein complex that is capable of carrying out some part of the process of cell adhesion to the cell matrix or to another cell." [GOC:dos] synonym: "cell adhesion complex" RELATED [] is_a: GO:0032991 ! protein-containing complex intersection_of: GO:0032991 ! protein-containing complex intersection_of: capable_of_part_of GO:0007155 ! cell adhesion relationship: capable_of_part_of GO:0007155 ! cell adhesion [Term] id: GO:0098642 name: network-forming collagen trimer namespace: cellular_component def: "A collagen trimer that forms networks." [PMID:21421911] is_a: GO:0005581 ! collagen trimer intersection_of: GO:0005581 ! collagen trimer intersection_of: part_of GO:0098645 ! collagen network relationship: part_of GO:0098645 ! collagen network [Term] id: GO:0098643 name: banded collagen fibril namespace: cellular_component def: "A supramolecular assembly of fibrillar collagen complexes in the form of a long fiber (fibril) with transverse striations (bands)." [GOC:dos, PMID:21421911] is_a: GO:0098644 ! complex of collagen trimers is_a: GO:0099512 ! supramolecular fiber [Term] id: GO:0098644 name: complex of collagen trimers namespace: cellular_component def: "A complex of collagen trimers such as a fibril or collagen network." [GOC:dos] synonym: "Supramolecular aggregate of collagen" EXACT [PMID:19693541] synonym: "Supramolecular collagen assembly" EXACT [PMID:21421911] is_a: GO:0099080 ! supramolecular complex is_a: PR:000050567 ! protein-containing material entity relationship: has_part GO:0005581 ! collagen trimer relationship: part_of GO:0062023 ! collagen-containing extracellular matrix [Term] id: GO:0098645 name: collagen network namespace: cellular_component def: "A supramolecular complex that consists of collagen triple helices associated to form a network." [GOC:dos, PMID:21421911] is_a: GO:0098644 ! complex of collagen trimers is_a: GO:0099081 ! supramolecular polymer [Term] id: GO:0098651 name: basement membrane collagen trimer namespace: cellular_component def: "Any collagen timer that is part of a basement membrane." [GOC:dos, PMID:21421911] is_a: GO:0005581 ! collagen trimer intersection_of: GO:0005581 ! collagen trimer intersection_of: part_of GO:0005604 ! basement membrane relationship: part_of GO:0005604 ! basement membrane [Term] id: GO:0098655 name: monoatomic cation transmembrane transport namespace: biological_process alt_id: GO:0099132 def: "The process in which a monoatomic cation is transported across a membrane. Monatomic cations (also called simple cations) are positively charged ions consisting of exactly one atom." [GOC:dos, GOC:vw] synonym: "ATP hydrolysis coupled cation transmembrane transport" NARROW [] synonym: "cation transmembrane transport" BROAD [] is_a: GO:0006812 ! monoatomic cation transport is_a: GO:0034220 ! monoatomic ion transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:23906 ! monoatomic cation intersection_of: results_in_transport_across GO:0016020 ! membrane [Term] id: GO:0098657 name: import into cell namespace: biological_process def: "The directed movement of some substance from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis." [GOC:dos] synonym: "uptake" BROAD [] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:24431 ! chemical entity intersection_of: has_target_end_location GO:0005737 ! cytoplasm intersection_of: has_target_start_location GO:0005576 ! extracellular region relationship: has_primary_input CHEBI:24431 ! chemical entity relationship: has_target_end_location GO:0005737 ! cytoplasm relationship: has_target_start_location GO:0005576 ! extracellular region [Term] id: GO:0098660 name: inorganic ion transmembrane transport namespace: biological_process def: "The process in which an inorganic ion is transported across a membrane." [GOC:mah] comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "inorganic ion membrane transport" EXACT [] synonym: "transmembrane inorganic ion transport" EXACT [GOC:dph, GOC:tb] is_a: GO:0055085 ! transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:36914 ! inorganic ion intersection_of: results_in_transport_across GO:0016020 ! membrane relationship: has_primary_input CHEBI:36914 ! inorganic ion [Term] id: GO:0098661 name: inorganic anion transmembrane transport namespace: biological_process def: "The process in which an inorganic anion is transported across a membrane." [GOC:mah] comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "inorganic anion membrane transport" EXACT [] synonym: "transmembrane inorganic anion transport" EXACT [GOC:dph, GOC:tb] is_a: GO:0015698 ! inorganic anion transport is_a: GO:0098660 ! inorganic ion transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:24834 ! inorganic anion intersection_of: results_in_transport_across GO:0016020 ! membrane [Term] id: GO:0098662 name: inorganic cation transmembrane transport namespace: biological_process alt_id: GO:0015672 alt_id: GO:0072511 def: "A process in which an inorganic cation is transported from one side of a membrane to the other by means of some agent such as a transporter or pore." [GOC:mah] comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "divalent inorganic cation transport" NARROW [] synonym: "inorganic cation membrane transport" EXACT [] synonym: "monovalent inorganic cation transport" NARROW [] synonym: "transmembrane inorganic cation transport" EXACT [GOC:dph, GOC:tb] is_a: GO:0098660 ! inorganic ion transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:36915 ! inorganic cation intersection_of: results_in_transport_across GO:0016020 ! membrane relationship: has_primary_input CHEBI:36915 ! inorganic cation [Term] id: GO:0098722 name: asymmetric stem cell division namespace: biological_process def: "Division of a stem cell during which it retains its identity and buds off a daughter cell with a new identity." [GOC:dos, PMID:18513950] is_a: GO:0008356 ! asymmetric cell division is_a: GO:0017145 ! stem cell division intersection_of: GO:0008356 ! asymmetric cell division intersection_of: has_primary_input CL:0000034 ! stem cell [Term] id: GO:0098723 name: skeletal muscle myofibril namespace: cellular_component def: "A myofibril of a skeletal muscle fiber." [GOC:dos] is_a: GO:0030016 ! myofibril intersection_of: GO:0030016 ! myofibril intersection_of: part_of CL:0008002 ! skeletal muscle fiber relationship: part_of CL:0008002 ! skeletal muscle fiber [Term] id: GO:0098727 name: maintenance of cell number namespace: biological_process def: "Any process by which the numbers of cells of a particular type or in a tissue are maintained." [GOC:dos] is_a: GO:0032502 ! developmental process [Term] id: GO:0098728 name: germline stem cell asymmetric division namespace: biological_process def: "The self-renewing division of a germline stem cell, to produce a daughter stem cell and a daughter germ cell which will divide to form one or more gametes." [GOC:dos] is_a: GO:0042078 ! germ-line stem cell division is_a: GO:0098722 ! asymmetric stem cell division intersection_of: GO:0008356 ! asymmetric cell division intersection_of: has_primary_input CL:0000014 ! germ line stem cell [Term] id: GO:0098751 name: bone cell development namespace: biological_process def: "The process whose specific outcome is the progression of a bone cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:dos] comment: Not to be used for manual annotation. Please choose a more specific cell development term or if not possible, bone or bone tissue development. subset: gocheck_do_not_annotate is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0001035 ! bone cell relationship: part_of GO:0060348 ! bone development relationship: results_in_development_of CL:0001035 ! bone cell [Term] id: GO:0098754 name: detoxification namespace: biological_process def: "Any process that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance." [GOC:dos] subset: goslim_generic subset: goslim_pombe subset: goslim_prokaryote is_a: GO:0008150 ! biological process relationship: part_of GO:0009636 ! response to toxic substance [Term] id: GO:0098773 name: skin epidermis development namespace: biological_process def: "The process whose specific outcome is the progression of the skin epidermis over time, from its formation to the mature structure." [GOC:dos] is_a: GO:0008544 ! epidermis development is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001003 ! skin epidermis relationship: part_of GO:0043588 ! skin development relationship: results_in_development_of UBERON:0001003 ! skin epidermis [Term] id: GO:0098793 name: presynapse namespace: cellular_component def: "The part of a synapse that is part of the presynaptic cell." [GOC:dos] subset: goslim_synapse synonym: "presynaptic terminal" EXACT [] is_a: GO:0110165 ! cellular anatomical entity relationship: part_of CL:0000540 ! neuron relationship: part_of GO:0045202 ! synapse [Term] id: GO:0098794 name: postsynapse namespace: cellular_component def: "The part of a synapse that is part of the post-synaptic cell." [GOC:dos] subset: goslim_synapse is_a: GO:0110165 ! cellular anatomical entity relationship: part_of CL:0000000 ! cell relationship: part_of GO:0045202 ! synapse [Term] id: GO:0098796 name: membrane protein complex namespace: cellular_component def: "Any protein complex that is part of a membrane." [GOC:dos] subset: goslim_metagenomics is_a: GO:0032991 ! protein-containing complex intersection_of: GO:0032991 ! protein-containing complex intersection_of: part_of GO:0016020 ! membrane relationship: part_of GO:0016020 ! membrane [Term] id: GO:0098797 name: plasma membrane protein complex namespace: cellular_component def: "Any protein complex that is part of the plasma membrane." [GOC:dos] is_a: GO:0098796 ! membrane protein complex intersection_of: GO:0032991 ! protein-containing complex intersection_of: part_of GO:0005886 ! plasma membrane relationship: part_of GO:0005886 ! plasma membrane [Term] id: GO:0098801 name: regulation of renal system process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by the renal system." [GOC:dos] is_a: GO:0044057 ! regulation of system process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003014 ! renal system process relationship: regulates GO:0003014 ! renal system process [Term] id: GO:0098813 name: nuclear chromosome segregation namespace: biological_process def: "The process in which genetic material, in the form of nuclear chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. Nuclear chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles." [GOC:dos] is_a: GO:0007059 ! chromosome segregation [Term] id: GO:0098840 name: protein transport along microtubule namespace: biological_process def: "The directed movement of a protein along a microtubule, mediated by motor proteins." [PMID:25987607] synonym: "microtubule-based protein transport" BROAD [] is_a: GO:0006886 ! intracellular protein transport is_a: GO:0010970 ! transport along microtubule is_a: GO:0099118 ! microtubule-based protein transport intersection_of: GO:0046907 ! intracellular transport intersection_of: has_primary_input PR:000000001 ! protein intersection_of: results_in_transport_along GO:0005874 ! microtubule [Term] id: GO:0098858 name: actin-based cell projection namespace: cellular_component def: "A cell projection supported by an assembly of actin filaments, and which lacks microtubules." [PMID:15661519] is_a: GO:0120025 ! plasma membrane bounded cell projection relationship: has_part GO:0005884 ! actin filament [Term] id: GO:0098867 name: intramembranous bone growth namespace: biological_process def: "The increase in size or mass of an intramembranous bone that contributes to the shaping of the bone." [PMID:26399686] is_a: GO:0098868 ! bone growth intersection_of: GO:0048589 ! developmental growth intersection_of: results_in_growth_of UBERON:0002514 ! intramembranous bone relationship: results_in_growth_of UBERON:0002514 ! intramembranous bone [Term] id: GO:0098868 name: bone growth namespace: biological_process def: "The increase in size or mass of a bone that contributes to the shaping of that bone." [GOC:dos] is_a: GO:0035265 ! organ growth intersection_of: GO:0048589 ! developmental growth intersection_of: results_in_growth_of UBERON:0001474 ! bone element relationship: part_of GO:0060348 ! bone development relationship: results_in_growth_of UBERON:0001474 ! bone element [Term] id: GO:0098871 name: postsynaptic actin cytoskeleton namespace: cellular_component def: "The actin cytoskeleton that is part of a postsynapse." [GOC:dos] subset: goslim_synapse is_a: GO:0015629 ! actin cytoskeleton is_a: GO:0099571 ! postsynaptic cytoskeleton intersection_of: GO:0015629 ! actin cytoskeleton intersection_of: part_of GO:0098794 ! postsynapse [Term] id: GO:0098876 name: vesicle-mediated transport to the plasma membrane namespace: biological_process def: "The directed movement of substances to the plasma membrane in transport vesicles that fuse with the plasma membrane by exocytosis." [GOC:dos] is_a: GO:0016192 ! vesicle-mediated transport is_a: GO:0051668 ! localization within membrane intersection_of: GO:0006810 ! transport intersection_of: has_target_end_location GO:0005886 ! plasma membrane intersection_of: process_has_causal_agent GO:0031982 ! vesicle relationship: ends_with GO:0006887 ! exocytosis relationship: has_target_end_location GO:0005886 ! plasma membrane [Term] id: GO:0098883 name: synapse pruning namespace: biological_process def: "A cellular process that results in the controlled breakdown of synapse. After it starts the process is continuous until the synapse has disappeared." [GOC:dos, PMID:12062020, PMID:18083105, PMID:22632716, PMID:29844190] subset: goslim_synapse synonym: "synapse clearance" EXACT [GOC:aruk, GOC:bc, PMID:22632716] synonym: "synapse disassembly" EXACT syngo_official_label [PMID:12062020] synonym: "synapse elimination" EXACT [GOC:aruk, GOC:bc, PMID:18083105, PMID:29844190] synonym: "synapse removal" EXACT [GOC:aruk, GOC:bc, PMID:22632716] is_a: GO:0050808 ! synapse organization is_a: GO:0150146 ! cell junction disassembly intersection_of: GO:0022411 ! cellular component disassembly intersection_of: results_in_disassembly_of GO:0045202 ! synapse relationship: results_in_disassembly_of GO:0045202 ! synapse [Term] id: GO:0098900 name: regulation of action potential namespace: biological_process def: "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:dos, GOC:dph, GOC:go_curators, GOC:tb, ISBN:978-0-07-139011-8] comment: The ion channels through which current flows during an action potential should be annotated to the process 'action potential'. Gene products involved in modulating the characteristics of an action potential via changing the expression levels or the activity of these channels (e.g. modulating their kinetics or voltage sensitivity) should be annotated to this regulation term. is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0050789 ! regulation of biological process intersection_of: regulates GO:0001508 ! action potential relationship: regulates GO:0001508 ! action potential [Term] id: GO:0098901 name: regulation of cardiac muscle cell action potential namespace: biological_process def: "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:dos, GOC:mtg_cardiac_conduct_nov11] is_a: GO:0098900 ! regulation of action potential intersection_of: GO:0050789 ! regulation of biological process intersection_of: regulates GO:0086001 ! cardiac muscle cell action potential relationship: regulates GO:0086001 ! cardiac muscle cell action potential [Term] id: GO:0098904 name: regulation of AV node cell action potential namespace: biological_process def: "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an atrioventricular node myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "regulation of atrioventricular node cardiac muscle cell action potential" EXACT [] synonym: "regulation of AV node cardiac muscle cell action potential" EXACT [] is_a: GO:0010646 ! regulation of cell communication is_a: GO:0098901 ! regulation of cardiac muscle cell action potential intersection_of: GO:0050789 ! regulation of biological process intersection_of: regulates GO:0086016 ! AV node cell action potential relationship: regulates GO:0086016 ! AV node cell action potential created_by: tb creation_date: 2011-11-10T08:58:56Z [Term] id: GO:0098906 name: regulation of Purkinje myocyte action potential namespace: biological_process def: "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a Purkinje myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] is_a: GO:0010646 ! regulation of cell communication is_a: GO:0098901 ! regulation of cardiac muscle cell action potential intersection_of: GO:0050789 ! regulation of biological process intersection_of: regulates GO:0086017 ! Purkinje myocyte action potential relationship: regulates GO:0086017 ! Purkinje myocyte action potential created_by: tb creation_date: 2011-11-10T08:58:56Z [Term] id: GO:0098907 name: regulation of SA node cell action potential namespace: biological_process def: "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an SA node cardiac myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "regulation of SA node cardiac muscle cell action potential" EXACT [] synonym: "regulation of SAN cardiac muscle cell action potential" EXACT [] synonym: "regulation of sinoatrial node cardiac muscle cell action potential" EXACT [] synonym: "regulation of sinus node cardiac muscle cell action potential" NARROW [] is_a: GO:0010646 ! regulation of cell communication is_a: GO:0098901 ! regulation of cardiac muscle cell action potential intersection_of: GO:0050789 ! regulation of biological process intersection_of: regulates GO:0086015 ! SA node cell action potential relationship: regulates GO:0086015 ! SA node cell action potential created_by: tb creation_date: 2011-11-10T08:50:15Z [Term] id: GO:0098908 name: regulation of neuronal action potential namespace: biological_process def: "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a neuron. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:dph, GOC:isa_complete, GOC:tb] synonym: "generation of action potential" RELATED [GOC:dph, GOC:tb] is_a: GO:0051969 ! regulation of transmission of nerve impulse is_a: GO:0098900 ! regulation of action potential intersection_of: GO:0050789 ! regulation of biological process intersection_of: regulates GO:0019228 ! neuronal action potential relationship: regulates GO:0019228 ! neuronal action potential [Term] id: GO:0098916 name: anterograde trans-synaptic signaling namespace: biological_process def: "Cell-cell signaling from pre to post-synapse, across the synaptic cleft." [GOC:dos] is_a: GO:0099537 ! trans-synaptic signaling intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: has_end_location GO:0098794 ! postsynapse intersection_of: has_start_location GO:0098793 ! presynapse relationship: has_end_location GO:0098794 ! postsynapse relationship: has_start_location GO:0098793 ! presynapse [Term] id: GO:0098917 name: retrograde trans-synaptic signaling namespace: biological_process def: "Cell-cell signaling from post to pre-synapse, across the synaptic cleft." [GOC:dos] is_a: GO:0099537 ! trans-synaptic signaling intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: has_end_location GO:0098793 ! presynapse intersection_of: has_start_location GO:0098794 ! postsynapse relationship: has_end_location GO:0098793 ! presynapse relationship: has_start_location GO:0098794 ! postsynapse [Term] id: GO:0098920 name: retrograde trans-synaptic signaling by lipid namespace: biological_process def: "Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a lipid ligand." [GOC:dos] subset: goslim_synapse is_a: GO:0098917 ! retrograde trans-synaptic signaling is_a: GO:0099541 ! trans-synaptic signaling by lipid intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: has_end_location GO:0098793 ! presynapse intersection_of: has_start_location GO:0098794 ! postsynapse intersection_of: process_has_causal_agent CHEBI:18059 ! lipid [Term] id: GO:0098926 name: postsynaptic signal transduction namespace: biological_process def: "Signal transduction in which the initial step occurs in a postsynapse." [GOC:dos] subset: goslim_synapse synonym: "postsynaptic signaling pathway" EXACT syngo_official_label [] is_a: GO:0007165 ! signal transduction intersection_of: GO:0007165 ! signal transduction intersection_of: has_start_location GO:0098794 ! postsynapse relationship: has_start_location GO:0098794 ! postsynapse relationship: part_of GO:0099536 ! synaptic signaling [Term] id: GO:0098928 name: presynaptic signal transduction namespace: biological_process def: "Signal transduction in which the initial step occurs in a presynapse." [GOC:dos] subset: goslim_synapse synonym: "presynaptic signaling pathway" EXACT syngo_official_label [] is_a: GO:0007165 ! signal transduction intersection_of: GO:0007165 ! signal transduction intersection_of: has_start_location GO:0098793 ! presynapse relationship: has_start_location GO:0098793 ! presynapse [Term] id: GO:0098974 name: postsynaptic actin cytoskeleton organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the postsynaptic actin cytoskeleton." [GOC:dos] subset: goslim_synapse is_a: GO:0030036 ! actin cytoskeleton organization is_a: GO:0099188 ! postsynaptic cytoskeleton organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0098871 ! postsynaptic actin cytoskeleton relationship: results_in_organization_of GO:0098871 ! postsynaptic actin cytoskeleton [Term] id: GO:0098975 name: postsynapse of neuromuscular junction namespace: cellular_component def: "The postsynapse of a neuromuscular junction. In vertebrate muscles this includes the motor end-plate, consisting of postjunctional folds of the sarcolemma." [GOC:dos, Wikipedia:Neuromuscular_junction&oldid=723623502] is_a: GO:0098794 ! postsynapse is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: GO:0098794 ! postsynapse intersection_of: part_of CL:0000187 ! muscle cell intersection_of: part_of GO:0031594 ! neuromuscular junction relationship: part_of CL:0000187 ! muscle cell relationship: part_of GO:0031594 ! neuromuscular junction [Term] id: GO:0098981 name: cholinergic synapse namespace: cellular_component def: "A synapse that uses acetylcholine as a neurotransmitter." [GOC:dos] subset: goslim_synapse is_a: GO:0045202 ! synapse intersection_of: GO:0045202 ! synapse intersection_of: capable_of GO:0007271 ! synaptic transmission, cholinergic relationship: capable_of GO:0007271 ! synaptic transmission, cholinergic [Term] id: GO:0098992 name: neuronal dense core vesicle namespace: cellular_component def: "A dense core vesicle (granule) that is part of a neuron. These vesicles typically contain neuropeptides. They can be found in all parts of neurons, including the soma, dendrites, axonal swellings (varicosities) and synaptic terminals." [GOC:dos, ISBN:978-0-07-181001-2, Wikipedia:Neuropeptide&oldid=713905176] subset: goslim_synapse is_a: GO:0031045 ! dense core granule intersection_of: GO:0031045 ! dense core granule intersection_of: part_of CL:0000540 ! neuron relationship: part_of CL:0000540 ! neuron [Term] id: GO:0099003 name: vesicle-mediated transport in synapse namespace: biological_process def: "Any vesicle-mediated transport that occurs in a synapse." [GOC:dos] subset: goslim_synapse is_a: GO:0016192 ! vesicle-mediated transport intersection_of: GO:0016192 ! vesicle-mediated transport intersection_of: occurs_in GO:0045202 ! synapse relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: occurs_in GO:0045202 ! synapse relationship: only_in_taxon NCBITaxon:33208 ! Metazoa [Term] id: GO:0099012 name: neuronal dense core vesicle membrane namespace: cellular_component def: "The lipid bilayer surrounding a neuronal dense core vesicle." [GOC:dos] subset: goslim_synapse is_a: GO:0032127 ! dense core granule membrane intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0098992 ! neuronal dense core vesicle relationship: bounding_layer_of GO:0098992 ! neuronal dense core vesicle relationship: part_of GO:0098992 ! neuronal dense core vesicle [Term] id: GO:0099014 name: neuronal dense core vesicle organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuronal dense core vesicle." [GOC:dos] is_a: GO:0061109 ! dense core granule organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0098992 ! neuronal dense core vesicle relationship: results_in_organization_of GO:0098992 ! neuronal dense core vesicle [Term] id: GO:0099054 name: presynapse assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form a presynapse." [GOC:bf, GOC:dos, GOC:PARL, PMID:24449494] subset: goslim_synapse synonym: "presynapse biogenesis" EXACT [GOC:mah] synonym: "presynaptic terminal assembly" EXACT [PMID:24449494] is_a: GO:0022607 ! cellular component assembly is_a: GO:0099172 ! presynapse organization intersection_of: GO:0009987 ! cellular process intersection_of: results_in_assembly_of GO:0098793 ! presynapse relationship: part_of GO:0007416 ! synapse assembly relationship: results_in_assembly_of GO:0098793 ! presynapse [Term] id: GO:0099068 name: postsynapse assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form a postsynapse." [GOC:bf, GOC:dos, GOCL:PARL] synonym: "postsynapse biogenesis" EXACT [GOC:mah] is_a: GO:0022607 ! cellular component assembly is_a: GO:0099173 ! postsynapse organization intersection_of: GO:0009987 ! cellular process intersection_of: results_in_assembly_of GO:0098794 ! postsynapse relationship: part_of GO:0007416 ! synapse assembly relationship: results_in_assembly_of GO:0098794 ! postsynapse [Term] id: GO:0099080 name: supramolecular complex namespace: cellular_component def: "A cellular component that consists of an indeterminate number of proteins or macromolecular complexes, organized into a regular, higher-order structure such as a polymer, sheet, network or a fiber." [GOC:dos] is_a: GO:0110165 ! cellular anatomical entity [Term] id: GO:0099081 name: supramolecular polymer namespace: cellular_component def: "A polymeric supramolecular structure." [GOC:dos] is_a: GO:0099080 ! supramolecular complex intersection_of: GO:0099080 ! supramolecular complex intersection_of: has_characteristic PATO:0015006 ! polymeric relationship: has_characteristic PATO:0015006 ! polymeric [Term] id: GO:0099082 name: retrograde trans-synaptic signaling by neuropeptide namespace: biological_process def: "Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a neuropeptide." [GOC:bf, GOC:dos, GOC:PARL, PMID:19448629] subset: goslim_synapse is_a: GO:0098917 ! retrograde trans-synaptic signaling is_a: GO:0099540 ! trans-synaptic signaling by neuropeptide intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: has_end_location GO:0098793 ! presynapse intersection_of: has_start_location GO:0098794 ! postsynapse intersection_of: process_has_causal_agent CHEBI:16670 ! peptide [Term] id: GO:0099083 name: retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission namespace: biological_process def: "Modulation of synaptic transmittion by cell-cell signaling across the synaptic cleft from postsynapse to presynapse, mediated by a neuropeptide." [GOC:bf, GOC:dos, GOC:PARL, PMID:19448629] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0099082 ! retrograde trans-synaptic signaling by neuropeptide is_a: GO:0099551 ! trans-synaptic signaling by neuropeptide, modulating synaptic transmission intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: has_end_location GO:0098793 ! presynapse intersection_of: has_start_location GO:0098794 ! postsynapse intersection_of: process_has_causal_agent CHEBI:16670 ! peptide intersection_of: regulates GO:0007268 ! chemical synaptic transmission [Term] id: GO:0099098 name: microtubule polymerization based movement namespace: biological_process def: "The movement of a cellular component as a result of microtubule polymerization." [GOC:cjm, ISBN:0815316194] is_a: GO:0007018 ! microtubule-based movement intersection_of: GO:0007018 ! microtubule-based movement intersection_of: has_part GO:0046785 ! microtubule polymerization relationship: has_part GO:0046785 ! microtubule polymerization [Term] id: GO:0099111 name: microtubule-based transport namespace: biological_process def: "A microtubule-based process that results in the transport of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules." [GOC:cjm, ISBN:0815316194] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: process_has_causal_agent GO:0005874 ! microtubule relationship: process_has_causal_agent GO:0005874 ! microtubule [Term] id: GO:0099112 name: microtubule polymerization based protein transport namespace: biological_process def: "The transport of a protein driven by polymerization of a microtubule to which it is attached." [GOC:dos, GOC:vw, PMID:11018050] is_a: GO:0007017 ! microtubule-based process is_a: GO:0045184 ! establishment of protein localization is_a: GO:0046907 ! intracellular transport is_a: GO:0071702 ! organic substance transport is_a: GO:0099111 ! microtubule-based transport intersection_of: GO:0046907 ! intracellular transport intersection_of: has_part GO:0046785 ! microtubule polymerization intersection_of: has_primary_input CHEBI:36080 ! protein intersection_of: process_has_causal_agent GO:0005874 ! microtubule relationship: has_part GO:0046785 ! microtubule polymerization [Term] id: GO:0099118 name: microtubule-based protein transport namespace: biological_process def: "A microtubule-based process that results in the transport of proteins." [GOC:vw] is_a: GO:0007017 ! microtubule-based process is_a: GO:0015031 ! protein transport is_a: GO:0099111 ! microtubule-based transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input PR:000000001 ! protein intersection_of: process_has_causal_agent GO:0005874 ! microtubule [Term] id: GO:0099140 name: presynaptic actin cytoskeleton organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the presynaptic actin cytoskeleton." [GOC:dos] subset: goslim_synapse is_a: GO:0030036 ! actin cytoskeleton organization is_a: GO:0099187 ! presynaptic cytoskeleton organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0099143 ! presynaptic actin cytoskeleton relationship: results_in_organization_of GO:0099143 ! presynaptic actin cytoskeleton created_by: dos creation_date: 2017-06-09T18:34:19Z [Term] id: GO:0099143 name: presynaptic actin cytoskeleton namespace: cellular_component def: "The actin cytoskeleton that is part of a presynapse." [GOC:dos] subset: goslim_synapse is_a: GO:0015629 ! actin cytoskeleton is_a: GO:0099569 ! presynaptic cytoskeleton intersection_of: GO:0015629 ! actin cytoskeleton intersection_of: part_of GO:0098793 ! presynapse created_by: dos creation_date: 2017-06-09T18:36:19Z [Term] id: GO:0099156 name: cell-cell signaling via exosome namespace: biological_process def: "Cell-cell signaling in which the ligand is carried between cells by an exosome." [GOC:dos, PMID:19837038] synonym: "exosome mediated" EXACT [] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: process_has_causal_agent GO:0070062 ! extracellular exosome relationship: process_has_causal_agent GO:0070062 ! extracellular exosome created_by: dos creation_date: 2017-07-05T16:40:45Z [Term] id: GO:0099157 name: trans-synaptic signaling via exosome namespace: biological_process def: "Transynaptic signaling in which the ligand is carried across the synapse by an exosome." [GOC:dos, PMID:19837038] subset: goslim_synapse synonym: "exosome mediated transynaptic signalling" EXACT [] synonym: "trans-synaptic signalling via exosome" EXACT [] is_a: GO:0099156 ! cell-cell signaling via exosome is_a: GO:0099537 ! trans-synaptic signaling intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: process_has_causal_agent GO:0070062 ! extracellular exosome created_by: dos creation_date: 2017-07-05T16:49:44Z [Term] id: GO:0099170 name: postsynaptic modulation of chemical synaptic transmission namespace: biological_process def: "Any process, acting in the postsynapse that results in modulation of chemical synaptic transmission." [GOC:dos] subset: goslim_synapse is_a: GO:0050804 ! modulation of chemical synaptic transmission intersection_of: GO:0050804 ! modulation of chemical synaptic transmission intersection_of: occurs_in GO:0098794 ! postsynapse relationship: occurs_in GO:0098794 ! postsynapse created_by: dos creation_date: 2017-09-11T17:09:17Z [Term] id: GO:0099171 name: presynaptic modulation of chemical synaptic transmission namespace: biological_process def: "Any process, acting in the presynapse that results in modulation of chemical synaptic transmission." [GOC:dos] subset: goslim_synapse is_a: GO:0050804 ! modulation of chemical synaptic transmission intersection_of: GO:0050804 ! modulation of chemical synaptic transmission intersection_of: occurs_in GO:0098793 ! presynapse relationship: occurs_in GO:0098793 ! presynapse created_by: dos creation_date: 2017-09-11T17:09:31Z [Term] id: GO:0099172 name: presynapse organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a presynapse." [GOC:dos] subset: goslim_synapse synonym: "presynapse development" EXACT [] synonym: "presynapse morphogenesis" RELATED [GOC:BHF] synonym: "presynapse organisation" EXACT [] synonym: "presynapse organization and biogenesis" RELATED [GOC:mah] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0009987 ! cellular process intersection_of: results_in_organization_of GO:0098793 ! presynapse relationship: part_of GO:0050808 ! synapse organization relationship: results_in_organization_of GO:0098793 ! presynapse [Term] id: GO:0099173 name: postsynapse organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a postsynapse." [GOC:dos] subset: goslim_synapse synonym: "postsynapse development" EXACT [] synonym: "postsynapse morphogenesis" RELATED [GOC:BHF] synonym: "postsynapse organisation" EXACT [] synonym: "postsynapse organization and biogenesis" RELATED [GOC:mah] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0009987 ! cellular process intersection_of: results_in_organization_of GO:0098794 ! postsynapse relationship: part_of GO:0050808 ! synapse organization relationship: results_in_organization_of GO:0098794 ! postsynapse [Term] id: GO:0099174 name: regulation of presynapse organization namespace: biological_process def: "Any process that modulates the physical form of a presynapse." [GOC:ai, GOC:dph, GOC:tb] subset: goslim_synapse synonym: "regulation of presynapse organisation" EXACT [GOC:mah] synonym: "regulation of presynapse organization and biogenesis" RELATED [GOC:mah] synonym: "regulation of presynapse structure" EXACT [] is_a: GO:0050807 ! regulation of synapse organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0099172 ! presynapse organization relationship: regulates GO:0099172 ! presynapse organization [Term] id: GO:0099175 name: regulation of postsynapse organization namespace: biological_process def: "Any process that modulates the physical form of a postsynapse." [GOC:ai, GOC:dph, GOC:tb] subset: goslim_synapse synonym: "regulation of postsynapse organisation" EXACT [GOC:mah] synonym: "regulation of postsynapse organization and biogenesis" RELATED [GOC:mah] synonym: "regulation of postsynapse structure" EXACT [] is_a: GO:0050807 ! regulation of synapse organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0099173 ! postsynapse organization relationship: regulates GO:0099173 ! postsynapse organization [Term] id: GO:0099177 name: regulation of trans-synaptic signaling namespace: biological_process def: "Any process that modulates the frequency, rate or extent of trans-synaptic signaling." [GOC:dos] is_a: GO:0010646 ! regulation of cell communication is_a: GO:0023051 ! regulation of signaling intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0099537 ! trans-synaptic signaling relationship: regulates GO:0099537 ! trans-synaptic signaling [Term] id: GO:0099187 name: presynaptic cytoskeleton organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures and their associated proteins in the presynaptic cytoskeleton." [GOC:dos] is_a: GO:0007010 ! cytoskeleton organization intersection_of: GO:0009987 ! cellular process intersection_of: results_in_organization_of GO:0099569 ! presynaptic cytoskeleton relationship: part_of GO:0099172 ! presynapse organization relationship: results_in_organization_of GO:0099569 ! presynaptic cytoskeleton created_by: dos creation_date: 2017-12-20T15:05:34Z [Term] id: GO:0099188 name: postsynaptic cytoskeleton organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising cytoskeletal filaments and their associated proteins in the postsynaptic cytoskeleton." [GOC:dos] subset: goslim_synapse is_a: GO:0007010 ! cytoskeleton organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0099571 ! postsynaptic cytoskeleton relationship: part_of GO:0099173 ! postsynapse organization relationship: results_in_organization_of GO:0099571 ! postsynaptic cytoskeleton created_by: dos creation_date: 2017-12-20T15:06:57Z [Term] id: GO:0099500 name: vesicle fusion to plasma membrane namespace: biological_process def: "Fusion of the membrane of a vesicle with the plasma membrane, thereby releasing its contents into the extracellular space." [GOC:aruk, GOC:bc, ISBN:0071120009, PMID:18618940] is_a: GO:0006906 ! vesicle fusion is_a: GO:0140029 ! exocytic process intersection_of: GO:0061025 ! membrane fusion intersection_of: part_of GO:0006887 ! exocytosis intersection_of: results_in_fusion_of GO:0012506 ! vesicle membrane intersection_of: results_in_fusion_of GO:0098590 ! plasma membrane region relationship: results_in_fusion_of GO:0098590 ! plasma membrane region [Term] id: GO:0099501 name: exocytic vesicle membrane namespace: cellular_component def: "The lipid bilayer surrounding an exocytic vesicle." [GOC:dos] synonym: "secretory vesicle membrane" BROAD [] is_a: GO:0030658 ! transport vesicle membrane intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0070382 ! exocytic vesicle relationship: bounding_layer_of GO:0070382 ! exocytic vesicle relationship: part_of GO:0070382 ! exocytic vesicle [Term] id: GO:0099503 name: secretory vesicle namespace: cellular_component def: "A cytoplasmic, membrane bound vesicle that is capable of fusing to the plasma membrane to release its contents into the extracellular space." [GOC:dos] subset: goslim_drosophila is_a: GO:0031410 ! cytoplasmic vesicle intersection_of: GO:0031982 ! vesicle intersection_of: capable_of GO:0099500 ! vesicle fusion to plasma membrane relationship: capable_of GO:0099500 ! vesicle fusion to plasma membrane [Term] id: GO:0099512 name: supramolecular fiber namespace: cellular_component alt_id: GO:0043205 def: "A polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure." [GOC:dos] synonym: "fibril" RELATED [] is_a: GO:0099081 ! supramolecular polymer intersection_of: GO:0099080 ! supramolecular complex intersection_of: has_characteristic PATO:0002309 ! fiber shaped intersection_of: has_characteristic PATO:0015006 ! polymeric relationship: has_characteristic PATO:0002309 ! fiber shaped [Term] id: GO:0099513 name: polymeric cytoskeletal fiber namespace: cellular_component def: "A component of the cytoskeleton consisting of a homo or heteropolymeric fiber constructed from an indeterminate number of protein subunits." [GOC:dos] is_a: GO:0099512 ! supramolecular fiber intersection_of: GO:0099512 ! supramolecular fiber intersection_of: has_characteristic PATO:0015006 ! polymeric intersection_of: part_of GO:0005856 ! cytoskeleton relationship: part_of GO:0005856 ! cytoskeleton [Term] id: GO:0099515 name: actin filament-based transport namespace: biological_process def: "The transport of organelles or other particles from one location in the cell to another along actin filaments." [GOC:dos, GOC:dph, GOC:mah, GOC:tb] is_a: GO:0030705 ! cytoskeleton-dependent intracellular transport intersection_of: GO:0046907 ! intracellular transport intersection_of: results_in_transport_along GO:0005884 ! actin filament relationship: results_in_transport_along GO:0005884 ! actin filament created_by: tb creation_date: 2009-05-27T10:56:08Z [Term] id: GO:0099518 name: vesicle cytoskeletal trafficking namespace: biological_process def: "The directed movement of a vesicle along a cytoskeletal fiber such as a microtubule or and actin filament, mediated by motor proteins." [GOC:ecd, GOC:rl] synonym: "cytoskeletal fiber-based vesicle localization" EXACT [GOC:rl] synonym: "vesicle cytoskeletal transport" EXACT [] is_a: GO:0030705 ! cytoskeleton-dependent intracellular transport is_a: GO:0051650 ! establishment of vesicle localization intersection_of: GO:0046907 ! intracellular transport intersection_of: has_primary_input GO:0031982 ! vesicle intersection_of: results_in_transport_along GO:0099513 ! polymeric cytoskeletal fiber [Term] id: GO:0099531 name: presynaptic process involved in chemical synaptic transmission namespace: biological_process def: "The pathway leading to secretion of a neurotransmitter from the presynapse as part of synaptic transmission." [GOC:dos] subset: gocheck_do_not_annotate subset: goslim_synapse is_a: GO:0050877 ! nervous system process intersection_of: GO:0050877 ! nervous system process intersection_of: occurs_in GO:0098793 ! presynapse intersection_of: part_of GO:0007268 ! chemical synaptic transmission relationship: occurs_in GO:0098793 ! presynapse relationship: part_of GO:0007268 ! chemical synaptic transmission [Term] id: GO:0099536 name: synaptic signaling namespace: biological_process def: "Cell-cell signaling to, from or within a synapse." [GOC:dos] subset: goslim_drosophila subset: goslim_synapse is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: occurs_in GO:0045202 ! synapse relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: occurs_in GO:0045202 ! synapse relationship: only_in_taxon NCBITaxon:33208 ! Metazoa [Term] id: GO:0099537 name: trans-synaptic signaling namespace: biological_process def: "Cell-cell signaling in either direction across the synaptic cleft." [GOC:dos] subset: goslim_synapse is_a: GO:0099536 ! synaptic signaling [Term] id: GO:0099538 name: synaptic signaling via neuropeptide namespace: biological_process def: "Cell-cell signaling to or from a synapse, mediated by a peptide." [GOC:dos] subset: goslim_synapse is_a: GO:0099536 ! synaptic signaling intersection_of: GO:0099536 ! synaptic signaling intersection_of: process_has_causal_agent CHEBI:16670 ! peptide relationship: process_has_causal_agent CHEBI:16670 ! peptide [Term] id: GO:0099540 name: trans-synaptic signaling by neuropeptide namespace: biological_process def: "Cell-cell signaling between presynapse and postsynapse mediated by a peptide ligand crossing the synaptic cleft." [GOC:dos] subset: goslim_synapse is_a: GO:0099537 ! trans-synaptic signaling is_a: GO:0099538 ! synaptic signaling via neuropeptide intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: process_has_causal_agent CHEBI:16670 ! peptide [Term] id: GO:0099541 name: trans-synaptic signaling by lipid namespace: biological_process def: "Cell-cell signaling from post to pre-synapse, across the synaptic cleft, mediated by a lipid." [GOC:dos] subset: goslim_synapse is_a: GO:0099537 ! trans-synaptic signaling intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: process_has_causal_agent CHEBI:18059 ! lipid relationship: process_has_causal_agent CHEBI:18059 ! lipid [Term] id: GO:0099546 name: protein catabolic process, modulating synaptic transmission namespace: biological_process def: "Any protein degradation process, occurring at a presynapse, that regulates synaptic transmission." [GOC:dos, PMID:23083742] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0140246 ! protein catabolic process at synapse intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:36080 ! protein intersection_of: occurs_in GO:0045202 ! synapse intersection_of: regulates GO:0007268 ! chemical synaptic transmission relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: regulates GO:0007268 ! chemical synaptic transmission [Term] id: GO:0099547 name: regulation of translation at synapse, modulating synaptic transmission namespace: biological_process def: "Any process that modulates synaptic transmission by regulating translation occurring at the synapse." [GOC:dos] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0050804 ! modulation of chemical synaptic transmission is_a: GO:0140243 ! regulation of translation at synapse intersection_of: GO:0065007 ! biological regulation intersection_of: occurs_in GO:0045202 ! synapse intersection_of: regulates GO:0006412 ! translation intersection_of: regulates GO:0007268 ! chemical synaptic transmission relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa [Term] id: GO:0099550 name: trans-synaptic signaling, modulating synaptic transmission namespace: biological_process def: "Cell-cell signaling between presynapse and postsynapse, across the synaptic cleft, that modulates the synaptic transmission properties of the synapse." [GOC:dos] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0050804 ! modulation of chemical synaptic transmission is_a: GO:0099537 ! trans-synaptic signaling intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: regulates GO:0007268 ! chemical synaptic transmission [Term] id: GO:0099551 name: trans-synaptic signaling by neuropeptide, modulating synaptic transmission namespace: biological_process def: "Cell-cell signaling between presynapse and postsynapse, via the vesicular release and reception of neuropeptide molecules, that modulates the synaptic transmission properties of the synapse." [GOC:dos] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0099540 ! trans-synaptic signaling by neuropeptide is_a: GO:0099550 ! trans-synaptic signaling, modulating synaptic transmission intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: process_has_causal_agent CHEBI:16670 ! peptide intersection_of: regulates GO:0007268 ! chemical synaptic transmission [Term] id: GO:0099552 name: trans-synaptic signaling by lipid, modulating synaptic transmission namespace: biological_process def: "Cell-cell signaling between presynapse and postsynapse, via the release and reception of lipid molecules, that modulates the synaptic transmission properties of the synapse." [GOC:dos, PMID:21531987] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0099541 ! trans-synaptic signaling by lipid is_a: GO:0099550 ! trans-synaptic signaling, modulating synaptic transmission intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: process_has_causal_agent CHEBI:18059 ! lipid intersection_of: regulates GO:0007268 ! chemical synaptic transmission [Term] id: GO:0099568 name: cytoplasmic region namespace: cellular_component def: "Any (proper) part of the cytoplasm of a single cell of sufficient size to still be considered cytoplasm." [GOC:dos] subset: gocheck_do_not_annotate is_a: GO:0005737 ! cytoplasm intersection_of: GO:0005737 ! cytoplasm intersection_of: part_of GO:0005737 ! cytoplasm relationship: part_of GO:0005737 ! cytoplasm [Term] id: GO:0099569 name: presynaptic cytoskeleton namespace: cellular_component def: "The portion of the cytoskeleton contained within the presynapse." [GOC:dos] subset: goslim_synapse is_a: GO:0005856 ! cytoskeleton intersection_of: GO:0005856 ! cytoskeleton intersection_of: part_of GO:0098793 ! presynapse relationship: part_of GO:0098793 ! presynapse [Term] id: GO:0099571 name: postsynaptic cytoskeleton namespace: cellular_component def: "The portion of the cytoskeleton contained within the postsynapse." [GOC:dos, PMID:19889835] subset: goslim_synapse is_a: GO:0005856 ! cytoskeleton intersection_of: GO:0005856 ! cytoskeleton intersection_of: part_of GO:0098794 ! postsynapse relationship: part_of GO:0098794 ! postsynapse [Term] id: GO:0099574 name: regulation of protein catabolic process at synapse, modulating synaptic transmission namespace: biological_process def: "Any process that modulates synaptic transmission by regulating protein degradation at the synapse." [GOC:dos] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0050804 ! modulation of chemical synaptic transmission is_a: GO:0140250 ! regulation protein catabolic process at synapse intersection_of: GO:0065007 ! biological regulation intersection_of: has_primary_input CHEBI:36080 ! protein intersection_of: occurs_in GO:0045202 ! synapse intersection_of: regulates GO:0007268 ! chemical synaptic transmission intersection_of: regulates GO:0009056 ! catabolic process relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa [Term] id: GO:0099575 name: regulation of protein catabolic process at presynapse, modulating synaptic transmission namespace: biological_process def: "Any process that modulates synaptic transmission by regulating a catabolic process occurring at a presynapse." [GOC:dos] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0042176 ! regulation of protein catabolic process is_a: GO:0099171 ! presynaptic modulation of chemical synaptic transmission intersection_of: GO:0042176 ! regulation of protein catabolic process intersection_of: occurs_in GO:0098793 ! presynapse intersection_of: regulates GO:0007268 ! chemical synaptic transmission [Term] id: GO:0099576 name: regulation of protein catabolic process at postsynapse, modulating synaptic transmission namespace: biological_process def: "Any process that modulates synaptic transmission by regulating a catabolic process occurring at a postsynapse." [GOC:dos] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0042176 ! regulation of protein catabolic process is_a: GO:0099170 ! postsynaptic modulation of chemical synaptic transmission intersection_of: GO:0042176 ! regulation of protein catabolic process intersection_of: occurs_in GO:0098794 ! postsynapse intersection_of: regulates GO:0007268 ! chemical synaptic transmission [Term] id: GO:0099577 name: regulation of translation at presynapse, modulating synaptic transmission namespace: biological_process def: "Any process that modulates synaptic transmission by regulating translation occurring at the presynapse." [GOC:dos] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0099171 ! presynaptic modulation of chemical synaptic transmission is_a: GO:0099547 ! regulation of translation at synapse, modulating synaptic transmission is_a: GO:0140244 ! regulation of translation at presynapse intersection_of: GO:0065007 ! biological regulation intersection_of: occurs_in GO:0098793 ! presynapse intersection_of: regulates GO:0006412 ! translation intersection_of: regulates GO:0007268 ! chemical synaptic transmission [Term] id: GO:0099578 name: regulation of translation at postsynapse, modulating synaptic transmission namespace: biological_process def: "Any process that modulates synaptic transmission by regulating translation occurring at the postsynapse." [GOC:dos] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0099170 ! postsynaptic modulation of chemical synaptic transmission is_a: GO:0099547 ! regulation of translation at synapse, modulating synaptic transmission is_a: GO:0140245 ! regulation of translation at postsynapse intersection_of: GO:0065007 ! biological regulation intersection_of: occurs_in GO:0098794 ! postsynapse intersection_of: regulates GO:0006412 ! translation intersection_of: regulates GO:0007268 ! chemical synaptic transmission [Term] id: GO:0099632 name: protein transport within plasma membrane namespace: biological_process def: "A process in which protein is transported from one region of the plasma membrane to another." [GOC:dos] is_a: GO:0032594 ! protein transport within lipid bilayer intersection_of: GO:0006810 ! transport intersection_of: has_primary_input PR:000000001 ! protein intersection_of: occurs_in GO:0005886 ! plasma membrane relationship: occurs_in GO:0005886 ! plasma membrane [Term] id: GO:0099640 name: axo-dendritic protein transport namespace: biological_process def: "The directed movement of proteins along microtubules in neuron projections." [ISBN:0815316194] subset: goslim_synapse synonym: "axonal protein transport" NARROW [] is_a: GO:0008088 ! axo-dendritic transport is_a: GO:0098840 ! protein transport along microtubule intersection_of: GO:0046907 ! intracellular transport intersection_of: has_primary_input PR:000000001 ! protein intersection_of: occurs_in GO:0043005 ! neuron projection intersection_of: results_in_transport_along GO:0005874 ! microtubule [Term] id: GO:0099643 name: signal release from synapse namespace: biological_process def: "Any signal release from a synapse." [GOC:dos] subset: goslim_synapse is_a: GO:0023061 ! signal release intersection_of: GO:0023061 ! signal release intersection_of: occurs_in GO:0045202 ! synapse relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: occurs_in GO:0045202 ! synapse relationship: only_in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0099536 ! synaptic signaling [Term] id: GO:0099738 name: cell cortex region namespace: cellular_component def: "The complete extent of cell cortex that underlies some some region of the plasma membrane." [GOC:dos] subset: gocheck_do_not_annotate synonym: "perimembrane region" EXACT [] is_a: GO:0005938 ! cell cortex is_a: GO:0099568 ! cytoplasmic region intersection_of: GO:0005938 ! cell cortex intersection_of: part_of GO:0005938 ! cell cortex relationship: part_of GO:0005938 ! cell cortex [Term] id: GO:0100001 name: regulation of skeletal muscle contraction by action potential namespace: biological_process def: "Any action potential process that regulates skeletal muscle contraction." [GOC:cjm, GOC:obol] is_a: BFO:0000015 ! process is_a: GO:0001508 ! action potential intersection_of: GO:0001508 ! action potential intersection_of: regulates GO:0003009 ! skeletal muscle contraction relationship: regulates GO:0003009 ! skeletal muscle contraction created_by: cjm creation_date: 2015-04-02T04:13:19Z [Term] id: GO:0101023 name: vascular endothelial cell proliferation namespace: biological_process def: "The multiplication or reproduction of blood vessel endothelial cells, resulting in the expansion of a cell population." [GOC:BHF, GOC:BHF_telomere, GOC:nc, PMID:23201774] is_a: GO:0001935 ! endothelial cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000071 ! blood vessel endothelial cell relationship: acts_on_population_of CL:0000071 ! blood vessel endothelial cell [Term] id: GO:0101024 name: mitotic nuclear membrane organization namespace: biological_process def: "A mitotic cell cycle process which results in the assembly, arrangement, or disassembly of the nuclear inner or outer membrane during mitosis." [GOC:vw, PMID:15147872] comment: This process only occurs in organisms which undergo 'closed mitosis' without nuclear breakdown. synonym: "nuclear membrane organization involved in mitotic nuclear division" EXACT [] is_a: GO:0071763 ! nuclear membrane organization is_a: GO:1903047 ! mitotic cell cycle process intersection_of: GO:0071763 ! nuclear membrane organization intersection_of: part_of GO:0140014 ! mitotic nuclear division relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota relationship: part_of GO:0140014 ! mitotic nuclear division property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19949" xsd:anyURI [Term] id: GO:0101025 name: nuclear membrane biogenesis namespace: biological_process def: "The process in which a nuclear membrane is synthesized, aggregates, and bonds together." [GOC:vw] is_a: GO:0044091 ! membrane biogenesis intersection_of: GO:0044085 ! cellular component biogenesis intersection_of: has_primary_output GO:0031965 ! nuclear membrane relationship: has_primary_output GO:0031965 ! nuclear membrane relationship: part_of GO:0071763 ! nuclear membrane organization [Term] id: GO:0106027 name: neuron projection organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a neuron, e.g. an axon, or a dendrite." [GOC:aruk, GOC:bc, PMID:11585923] is_a: GO:0120036 ! plasma membrane bounded cell projection organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0043005 ! neuron projection relationship: results_in_organization_of GO:0043005 ! neuron projection created_by: hjd creation_date: 2017-06-23T18:30:18Z [Term] id: GO:0106214 name: regulation of vesicle fusion with Golgi apparatus namespace: biological_process def: "Any process that modulates the frequency, rate or extent of vesicle fusion with Golgi apparatus." [GOC:se, PMID:26195667] is_a: GO:0031338 ! regulation of vesicle fusion is_a: GO:1903358 ! regulation of Golgi organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048280 ! vesicle fusion with Golgi apparatus relationship: regulates GO:0048280 ! vesicle fusion with Golgi apparatus created_by: hjd creation_date: 2019-06-27T15:12:22Z [Term] id: GO:0106215 name: negative regulation of vesicle fusion with Golgi apparatus namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of vesicle fustion with Golgi apparatus." [GOC:se, PMID:26195667] is_a: GO:0031339 ! negative regulation of vesicle fusion is_a: GO:0106214 ! regulation of vesicle fusion with Golgi apparatus intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048280 ! vesicle fusion with Golgi apparatus relationship: negatively_regulates GO:0048280 ! vesicle fusion with Golgi apparatus created_by: hjd creation_date: 2019-06-27T15:17:17Z [Term] id: GO:0106216 name: positive regulation of vesicle fusion with Golgi apparatus namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of vesicle fusion with Golgi apparatus." [GOC:se, PMID:26195667] is_a: GO:0031340 ! positive regulation of vesicle fusion is_a: GO:0106214 ! regulation of vesicle fusion with Golgi apparatus intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048280 ! vesicle fusion with Golgi apparatus relationship: positively_regulates GO:0048280 ! vesicle fusion with Golgi apparatus created_by: hjd creation_date: 2019-06-27T15:20:59Z [Term] id: GO:0110011 name: regulation of basement membrane organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the assembly, disassembly or arrangement of constituent parts of the basement membrane." [GOC:ha, PMID:27404358] is_a: GO:1903053 ! regulation of extracellular matrix organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0071711 ! basement membrane organization relationship: regulates GO:0071711 ! basement membrane organization created_by: kmv [Term] id: GO:0110020 name: regulation of actomyosin structure organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin." [GOC:lf, PMID:22790195] is_a: GO:0032956 ! regulation of actin cytoskeleton organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0031032 ! actomyosin structure organization relationship: regulates GO:0031032 ! actomyosin structure organization created_by: kmv creation_date: 2017-06-20T19:28:58Z [Term] id: GO:0110021 name: cardiac muscle myoblast proliferation namespace: biological_process def: "The multiplication or reproduction of cardiac muscle myoblasts, resulting in the expansion of a cardiac muscle myoblast cell population. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:26512644] is_a: GO:0051450 ! myoblast proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000513 ! cardiac muscle myoblast relationship: acts_on_population_of CL:0000513 ! cardiac muscle myoblast created_by: kmv creation_date: 2017-06-29T14:35:24Z [Term] id: GO:0110022 name: regulation of cardiac muscle myoblast proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac muscle myoblast proliferation." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:26512644] is_a: GO:2000291 ! regulation of myoblast proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0110021 ! cardiac muscle myoblast proliferation relationship: regulates GO:0110021 ! cardiac muscle myoblast proliferation created_by: kmv creation_date: 2017-06-29T15:11:47Z [Term] id: GO:0110023 name: negative regulation of cardiac muscle myoblast proliferation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle myoblast proliferation." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:26512644] is_a: GO:0110022 ! regulation of cardiac muscle myoblast proliferation is_a: GO:2000818 ! negative regulation of myoblast proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0110021 ! cardiac muscle myoblast proliferation relationship: negatively_regulates GO:0110021 ! cardiac muscle myoblast proliferation created_by: kmv creation_date: 2017-06-29T15:18:30Z [Term] id: GO:0110024 name: positive regulation of cardiac muscle myoblast proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cardiac muscle myoblast proliferation." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:26512644] is_a: GO:0110022 ! regulation of cardiac muscle myoblast proliferation is_a: GO:2000288 ! positive regulation of myoblast proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0110021 ! cardiac muscle myoblast proliferation relationship: positively_regulates GO:0110021 ! cardiac muscle myoblast proliferation created_by: kmv creation_date: 2017-06-29T15:24:16Z [Term] id: GO:0110053 name: regulation of actin filament organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of actin filament organization." [GOC:kmv] is_a: GO:0032956 ! regulation of actin cytoskeleton organization is_a: GO:1902903 ! regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007015 ! actin filament organization relationship: regulates GO:0007015 ! actin filament organization created_by: kmv creation_date: 2017-09-20T19:52:57Z [Term] id: GO:0110057 name: regulation of blood vessel endothelial cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of blood vessel endothelial cell differentiation." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:23072816] is_a: GO:0045601 ! regulation of endothelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060837 ! blood vessel endothelial cell differentiation relationship: regulates GO:0060837 ! blood vessel endothelial cell differentiation created_by: kmv creation_date: 2017-10-23T14:32:09Z [Term] id: GO:0110058 name: positive regulation of blood vessel endothelial cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of blood vessel endothelial cell differentiation." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:23072816] is_a: GO:0045603 ! positive regulation of endothelial cell differentiation is_a: GO:0110057 ! regulation of blood vessel endothelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060837 ! blood vessel endothelial cell differentiation relationship: positively_regulates GO:0060837 ! blood vessel endothelial cell differentiation created_by: kmv creation_date: 2017-10-23T14:38:19Z [Term] id: GO:0110059 name: negative regulation of blood vessel endothelial cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel endothelial cell differentiation." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:23072816] is_a: GO:0045602 ! negative regulation of endothelial cell differentiation is_a: GO:0110057 ! regulation of blood vessel endothelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060837 ! blood vessel endothelial cell differentiation relationship: negatively_regulates GO:0060837 ! blood vessel endothelial cell differentiation created_by: kmv creation_date: 2017-10-23T14:47:29Z [Term] id: GO:0110077 name: vesicle-mediated intercellular transport namespace: biological_process def: "A cellular transport process in which transported substances are moved in extracellular vesicles between cells; transported substances are enclosed in the vesicle lumen or located in the extracellular vesicle membrane." [GOC:sp, PMID:29328915, PMID:29328916] is_a: GO:0010496 ! intercellular transport is_a: GO:0016192 ! vesicle-mediated transport intersection_of: GO:0010496 ! intercellular transport intersection_of: process_has_causal_agent GO:1903561 ! extracellular vesicle relationship: process_has_causal_agent GO:1903561 ! extracellular vesicle created_by: kmv creation_date: 2018-01-29T14:46:52Z [Term] id: GO:0110079 name: regulation of placenta blood vessel development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of placenta blood vessel development." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:27748453] is_a: GO:1901342 ! regulation of vasculature development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060674 ! placenta blood vessel development relationship: regulates GO:0060674 ! placenta blood vessel development created_by: kmv creation_date: 2018-02-01T14:49:12Z [Term] id: GO:0110080 name: positive regulation of placenta blood vessel development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of placenta blood vessel development." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:27748453] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0110079 ! regulation of placenta blood vessel development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060674 ! placenta blood vessel development relationship: positively_regulates GO:0060674 ! placenta blood vessel development created_by: kmv creation_date: 2018-02-01T14:55:30Z [Term] id: GO:0110081 name: negative regulation of placenta blood vessel development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of placenta blood vessel development." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:27748453] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0110079 ! regulation of placenta blood vessel development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060674 ! placenta blood vessel development relationship: negatively_regulates GO:0060674 ! placenta blood vessel development created_by: kmv creation_date: 2018-02-01T15:01:11Z [Term] id: GO:0110110 name: positive regulation of animal organ morphogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of animal organ morphogenesis." [GOC:kmv] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:2000027 ! regulation of animal organ morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0009887 ! animal organ morphogenesis relationship: positively_regulates GO:0009887 ! animal organ morphogenesis created_by: kmv creation_date: 2018-07-05T14:10:14Z [Term] id: GO:0110111 name: negative regulation of animal organ morphogenesis namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of animal organ morphogenesis." [GOC:kmv] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:2000027 ! regulation of animal organ morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0009887 ! animal organ morphogenesis relationship: negatively_regulates GO:0009887 ! animal organ morphogenesis created_by: kmv creation_date: 2018-07-05T14:25:21Z [Term] id: GO:0110112 name: regulation of lipid transporter activity namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of lipid transporter activity." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:27365390] subset: gocheck_do_not_annotate is_a: GO:0032368 ! regulation of lipid transport is_a: GO:0032409 ! regulation of transporter activity intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0005319 ! lipid transporter activity relationship: regulates GO:0005319 ! lipid transporter activity created_by: kmv creation_date: 2018-07-06T18:53:55Z [Term] id: GO:0110113 name: positive regulation of lipid transporter activity namespace: biological_process def: "Any process that increases the frequency, rate, or extent of lipid transporter activity." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:27365390] subset: gocheck_do_not_annotate is_a: GO:0032370 ! positive regulation of lipid transport is_a: GO:0032411 ! positive regulation of transporter activity is_a: GO:0110112 ! regulation of lipid transporter activity intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0005319 ! lipid transporter activity relationship: positively_regulates GO:0005319 ! lipid transporter activity created_by: kmv creation_date: 2018-07-06T19:14:13Z [Term] id: GO:0110114 name: negative regulation of lipid transporter activity namespace: biological_process def: "Any process that decreases the frequency, rate, or extent of lipid transporter activity." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:27365390] subset: gocheck_do_not_annotate is_a: GO:0032369 ! negative regulation of lipid transport is_a: GO:0032410 ! negative regulation of transporter activity is_a: GO:0110112 ! regulation of lipid transporter activity intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0005319 ! lipid transporter activity relationship: negatively_regulates GO:0005319 ! lipid transporter activity created_by: kmv creation_date: 2018-07-06T19:21:44Z [Term] id: GO:0110116 name: regulation of compound eye photoreceptor cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of compound eye photoreceptor cell differentiation." [GOC:ha, PMID:16377567] is_a: GO:0046532 ! regulation of photoreceptor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001751 ! compound eye photoreceptor cell differentiation relationship: regulates GO:0001751 ! compound eye photoreceptor cell differentiation created_by: kmv creation_date: 2018-07-16T18:08:49Z [Term] id: GO:0110117 name: positive regulation of compound eye photoreceptor cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor cell differentiation." [GOC:ha, PMID:16377567] is_a: GO:0046534 ! positive regulation of photoreceptor cell differentiation is_a: GO:0110116 ! regulation of compound eye photoreceptor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001751 ! compound eye photoreceptor cell differentiation relationship: positively_regulates GO:0001751 ! compound eye photoreceptor cell differentiation created_by: kmv creation_date: 2018-07-16T18:13:28Z [Term] id: GO:0110118 name: negative regulation of compound eye photoreceptor cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of compound eye photoreceptor cell differentiation." [GOC:ha, PMID:16377567] is_a: GO:0046533 ! negative regulation of photoreceptor cell differentiation is_a: GO:0110116 ! regulation of compound eye photoreceptor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001751 ! compound eye photoreceptor cell differentiation relationship: negatively_regulates GO:0001751 ! compound eye photoreceptor cell differentiation created_by: kmv creation_date: 2018-07-16T18:15:52Z [Term] id: GO:0110122 name: myotube cell migration namespace: biological_process def: "The orderly movement of a myotube cell from one site to another, often during the development of a multicellular organism. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate, and fuse." [GOC:ha, PMID:29122742] is_a: GO:0014812 ! muscle cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0002372 ! myotube relationship: results_in_movement_of CL:0002372 ! myotube created_by: kmv creation_date: 2018-08-22T20:58:09Z [Term] id: GO:0110123 name: regulation of myotube cell migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of myotube cell migration." [GOC:ha, PMID:29122742] is_a: GO:0030334 ! regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0110122 ! myotube cell migration relationship: regulates GO:0110122 ! myotube cell migration created_by: kmv creation_date: 2018-08-22T21:06:53Z [Term] id: GO:0110124 name: positive regulation of myotube cell migration namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of myotube cell migration." [GOC:ha, PMID:29122742] is_a: GO:0030335 ! positive regulation of cell migration is_a: GO:0110123 ! regulation of myotube cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0110122 ! myotube cell migration relationship: positively_regulates GO:0110122 ! myotube cell migration created_by: kmv creation_date: 2018-08-22T21:09:38Z [Term] id: GO:0110125 name: negative regulation of myotube cell migration namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of myotube cell migration." [GOC:ha, PMID:29122742] is_a: GO:0030336 ! negative regulation of cell migration is_a: GO:0110123 ! regulation of myotube cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0110122 ! myotube cell migration relationship: negatively_regulates GO:0110122 ! myotube cell migration created_by: kmv creation_date: 2018-08-22T21:12:47Z [Term] id: GO:0110165 name: cellular anatomical entity namespace: cellular_component def: "A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex." [GOC:kmv] subset: gocheck_do_not_annotate subset: goslim_pir is_a: CARO:0000000 ! anatomical entity is_a: GO:0005575 ! cellular_component is_a: UBERON:0000061 ! anatomical structure property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24200" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI created_by: kmv creation_date: 2019-08-12T18:01:37Z [Term] id: GO:0120025 name: plasma membrane bounded cell projection namespace: cellular_component def: "A prolongation or process extending from a cell and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon." [GOC:krc] is_a: GO:0042995 ! cell projection intersection_of: GO:0042995 ! cell projection intersection_of: has_part GO:0098590 ! plasma membrane region relationship: has_part GO:0098590 ! plasma membrane region property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/13193" xsd:anyURI created_by: krc creation_date: 2017-03-21T17:26:07Z [Term] id: GO:0120031 name: plasma membrane bounded cell projection assembly namespace: biological_process def: "Formation of a prolongation or process extending and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon." [GOC:krc] synonym: "eupodium" NARROW [GOC:krc, GOC:rjd, PMID:10328951, PMID:9096956] is_a: GO:0030031 ! cell projection assembly is_a: GO:0120036 ! plasma membrane bounded cell projection organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0120025 ! plasma membrane bounded cell projection relationship: results_in_assembly_of GO:0120025 ! plasma membrane bounded cell projection property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/13298" xsd:anyURI created_by: krc creation_date: 2017-04-24T23:56:08Z [Term] id: GO:0120032 name: regulation of plasma membrane bounded cell projection assembly namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of plasma membrane bounded cell projection assembly." [GOC:krc] is_a: GO:0060491 ! regulation of cell projection assembly is_a: GO:0120035 ! regulation of plasma membrane bounded cell projection organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0120031 ! plasma membrane bounded cell projection assembly relationship: regulates GO:0120031 ! plasma membrane bounded cell projection assembly property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/13298" xsd:anyURI created_by: krc creation_date: 2017-04-26T04:27:04Z [Term] id: GO:0120033 name: negative regulation of plasma membrane bounded cell projection assembly namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane bounded cell projection assembly." [GOC:krc] is_a: GO:0031345 ! negative regulation of cell projection organization is_a: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0120031 ! plasma membrane bounded cell projection assembly relationship: negatively_regulates GO:0120031 ! plasma membrane bounded cell projection assembly property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/13298" xsd:anyURI created_by: krc creation_date: 2017-04-26T04:34:31Z [Term] id: GO:0120034 name: positive regulation of plasma membrane bounded cell projection assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of plasma membrane bounded cell projection assembly." [GOC:krc] is_a: GO:0031346 ! positive regulation of cell projection organization is_a: GO:0044089 ! positive regulation of cellular component biogenesis is_a: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0120031 ! plasma membrane bounded cell projection assembly relationship: positively_regulates GO:0120031 ! plasma membrane bounded cell projection assembly property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/13298" xsd:anyURI created_by: krc creation_date: 2017-04-26T04:34:45Z [Term] id: GO:0120035 name: regulation of plasma membrane bounded cell projection organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of plasma membrane bounded cell projections." [GOC:krc] is_a: GO:0031344 ! regulation of cell projection organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0120036 ! plasma membrane bounded cell projection organization relationship: regulates GO:0120036 ! plasma membrane bounded cell projection organization property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/13298" xsd:anyURI created_by: krc creation_date: 2017-04-26T16:02:06Z [Term] id: GO:0120036 name: plasma membrane bounded cell projection organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasma membrane bounded prolongation or process extending from a cell, e.g. a cilium or axon." [GOC:krc] is_a: GO:0030030 ! cell projection organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0120025 ! plasma membrane bounded cell projection relationship: results_in_organization_of GO:0120025 ! plasma membrane bounded cell projection property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/13298" xsd:anyURI created_by: krc creation_date: 2017-04-26T16:07:02Z [Term] id: GO:0120039 name: plasma membrane bounded cell projection morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a plasma membrane bounded cell projection are generated and organized." [GOC:krc] is_a: GO:0048858 ! cell projection morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of GO:0120025 ! plasma membrane bounded cell projection relationship: results_in_morphogenesis_of GO:0120025 ! plasma membrane bounded cell projection property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/13298" xsd:anyURI created_by: krc creation_date: 2017-04-28T23:39:37Z [Term] id: GO:0120111 name: neuron projection cytoplasm namespace: cellular_component def: "All of the contents of a plasma membrane bounded neuron projection, excluding the plasma membrane surrounding the projection." [GOC:ha] is_a: GO:0032838 ! plasma membrane bounded cell projection cytoplasm intersection_of: GO:0005737 ! cytoplasm intersection_of: part_of GO:0043005 ! neuron projection relationship: part_of GO:0043005 ! neuron projection property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/14472" xsd:anyURI created_by: krc creation_date: 2017-11-01T18:58:12Z [Term] id: GO:0120158 name: positive regulation of collagen catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix." [GOC:dph, GOC:tb] synonym: "activation of collagen catabolic process" NARROW [GOC:dph, GOC:tb] synonym: "positive regulation of collagen breakdown" EXACT [GOC:dph, GOC:tb] synonym: "positive regulation of collagen catabolism" EXACT [GOC:dph, GOC:tb] synonym: "positive regulation of collagen degradation" EXACT [GOC:dph, GOC:tb] synonym: "up regulation of collagen catabolic process" EXACT [GOC:dph, GOC:tb] synonym: "up-regulation of collagen catabolic process" EXACT [GOC:dph, GOC:tb] synonym: "upregulation of collagen catabolic process" EXACT [GOC:dph, GOC:tb] is_a: GO:0009896 ! positive regulation of catabolic process is_a: GO:0010710 ! regulation of collagen catabolic process is_a: GO:0010714 ! positive regulation of collagen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030574 ! collagen catabolic process relationship: positively_regulates GO:0030574 ! collagen catabolic process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/15720" xsd:anyURI created_by: krc creation_date: 2018-05-11T16:31:42Z [Term] id: GO:0120178 name: steroid hormone biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of any steroid hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone." [GOC:krc, GOC:nln] is_a: GO:0006694 ! steroid biosynthetic process intersection_of: GO:0006694 ! steroid biosynthetic process intersection_of: has_primary_output CHEBI:26764 ! steroid hormone relationship: has_primary_output CHEBI:26764 ! steroid hormone property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/16000" xsd:anyURI created_by: krc creation_date: 2019-05-20T22:34:00Z [Term] id: GO:0120186 name: negative regulation of protein localization to chromatin namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to chromatin." [PMID:20889714, PMID:29899453] synonym: "negative regulation of protein localisation to chromatin" EXACT [GOC:krc] is_a: GO:1903828 ! negative regulation of protein localization is_a: GO:1905634 ! regulation of protein localization to chromatin intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0071168 ! protein localization to chromatin relationship: negatively_regulates GO:0071168 ! protein localization to chromatin property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/16012" xsd:anyURI created_by: krc creation_date: 2018-07-14T00:19:32Z [Term] id: GO:0120187 name: positive regulation of protein localization to chromatin namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein localization to chromatin." [PMID:20889714, PMID:29899453] synonym: "positive regulation of protein localisation to chromatin" EXACT [GOC:krc] is_a: GO:1903829 ! positive regulation of protein localization is_a: GO:1905634 ! regulation of protein localization to chromatin intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0071168 ! protein localization to chromatin relationship: positively_regulates GO:0071168 ! protein localization to chromatin property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/16012" xsd:anyURI created_by: krc creation_date: 2018-07-14T00:21:28Z [Term] id: GO:0120188 name: regulation of bile acid secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:22767443] is_a: GO:0051046 ! regulation of secretion intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0032782 ! bile acid secretion relationship: regulates GO:0032782 ! bile acid secretion property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/16040" xsd:anyURI created_by: krc creation_date: 2018-07-16T22:28:58Z [Term] id: GO:0120189 name: positive regulation of bile acid secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:22767443] is_a: GO:0051047 ! positive regulation of secretion is_a: GO:0120188 ! regulation of bile acid secretion intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0032782 ! bile acid secretion relationship: positively_regulates GO:0032782 ! bile acid secretion property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/16040" xsd:anyURI created_by: krc creation_date: 2018-07-16T22:36:17Z [Term] id: GO:0120190 name: negative regulation of bile acid secretion namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:22767443] is_a: GO:0051048 ! negative regulation of secretion is_a: GO:0120188 ! regulation of bile acid secretion intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0032782 ! bile acid secretion relationship: negatively_regulates GO:0032782 ! bile acid secretion property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/16040" xsd:anyURI created_by: krc creation_date: 2018-07-16T22:38:34Z [Term] id: GO:0120222 name: regulation of blastocyst development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of blastocyst development." [GOC:krc, PMID:29593216] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001824 ! blastocyst development relationship: regulates GO:0001824 ! blastocyst development property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/18871" xsd:anyURI created_by: krc creation_date: 2020-02-17T19:59:20Z [Term] id: GO:0120229 name: protein localization to motile cilium namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within a motile cilium." [GOC:krc, PMID:27486780] synonym: "protein localization to nonmotile primary cilium" RELATED [] is_a: GO:0061512 ! protein localization to cilium intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0031514 ! motile cilium relationship: has_target_end_location GO:0031514 ! motile cilium property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19588" xsd:anyURI created_by: krc creation_date: 2020-06-05T23:43:04Z [Term] id: GO:0120305 name: regulation of pigmentation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the deposition or modulates the distribution of coloring matter in an organism." [GOC:krc] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0043473 ! pigmentation relationship: regulates GO:0043473 ! pigmentation property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/20524" xsd:anyURI created_by: krc creation_date: 2021-02-09T19:37:35Z [Term] id: GO:0120316 name: sperm flagellum assembly namespace: biological_process def: "The assembly and organization of the sperm flagellum, the microtubule-based axoneme and associated structures that are part of a sperm flagellum (or cilium)." [GOC:krc, PMID:32791035] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0044458 ! motile cilium assembly intersection_of: GO:0044458 ! motile cilium assembly intersection_of: occurs_in CL:0000019 ! sperm relationship: occurs_in CL:0000019 ! sperm relationship: part_of GO:0007286 ! spermatid development relationship: part_of GO:0030317 ! flagellated sperm motility property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/21361" xsd:anyURI created_by: krc creation_date: 2021-04-29T01:27:27Z [Term] id: GO:0120331 name: endothelial tube formation namespace: biological_process def: "The developmental process pertaining to the initial formation of an endothelial tube." [GOC:sl, PMID:23239824] is_a: GO:0072175 ! epithelial tube formation intersection_of: GO:0035148 ! tube formation intersection_of: results_in_formation_of_anatomical_entity UBERON:0003915 ! endothelial tube relationship: part_of GO:0061154 ! endothelial tube morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0003915 ! endothelial tube property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22302" xsd:anyURI created_by: krc creation_date: 2022-05-25T16:17:59Z [Term] id: GO:0140013 name: meiotic nuclear division namespace: biological_process def: "One of the two nuclear divisions that occur as part of the meiotic cell cycle." [PMID:9334324] subset: goslim_generic synonym: "meiosis" EXACT [] is_a: GO:0000280 ! nuclear division is_a: GO:1903046 ! meiotic cell cycle process intersection_of: GO:0000280 ! nuclear division intersection_of: part_of GO:0051321 ! meiotic cell cycle property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19910" xsd:anyURI created_by: pg creation_date: 2017-03-23T09:40:00Z [Term] id: GO:0140014 name: mitotic nuclear division namespace: biological_process def: "A mitotic cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell." [ISBN:0198547684] subset: goslim_chembl subset: goslim_generic synonym: "mitosis" EXACT [] is_a: GO:0000280 ! nuclear division is_a: GO:1903047 ! mitotic cell cycle process intersection_of: GO:0000280 ! nuclear division intersection_of: part_of GO:0000278 ! mitotic cell cycle property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19910" xsd:anyURI created_by: pg creation_date: 2017-03-23T14:44:23Z [Term] id: GO:0140029 name: exocytic process namespace: biological_process def: "The cellular processes that contribute to exocytosis." [Wikipedia:Exocytosis] subset: gocheck_do_not_annotate is_a: GO:0009987 ! cellular process intersection_of: GO:0009987 ! cellular process intersection_of: part_of GO:0006887 ! exocytosis relationship: part_of GO:0006887 ! exocytosis created_by: pg creation_date: 2017-05-15T13:20:45Z [Term] id: GO:0140056 name: organelle localization by membrane tethering namespace: biological_process def: "The process by which an organelle membrane interacts with another membrane via molecular tethers that physically bridge the two membranes and attach them to each other." [PMID:27875684] subset: goslim_pombe is_a: GO:0022406 ! membrane docking is_a: GO:0051640 ! organelle localization created_by: pg creation_date: 2017-06-27T09:58:51Z [Term] id: GO:0140096 name: catalytic activity, acting on a protein namespace: molecular_function def: "Catalytic activity that acts to modify a protein." [GOC:molecular_function_refactoring, GOC:pdt] subset: goslim_generic subset: goslim_prokaryote is_a: GO:0003824 ! catalytic activity intersection_of: GO:0003824 ! catalytic activity intersection_of: has_primary_input PR:000000001 ! protein relationship: has_primary_input PR:000000001 ! protein property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/14225" xsd:anyURI created_by: pg creation_date: 2017-09-14T10:32:59Z [Term] id: GO:0140097 name: catalytic activity, acting on DNA namespace: molecular_function def: "Catalytic activity that acts to modify DNA." [GOC:molecular_function_refactoring, GOC:pdt] subset: goslim_generic subset: goslim_prokaryote is_a: GO:0140640 ! catalytic activity, acting on a nucleic acid intersection_of: GO:0003824 ! catalytic activity intersection_of: has_primary_input CHEBI:16991 ! deoxyribonucleic acid relationship: has_primary_input CHEBI:16991 ! deoxyribonucleic acid property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/14225" xsd:anyURI created_by: pg creation_date: 2017-09-14T12:03:51Z [Term] id: GO:0140098 name: catalytic activity, acting on RNA namespace: molecular_function def: "Catalytic activity that acts to modify RNA, driven by ATP hydrolysis." [GOC:molecular_function_refactoring, GOC:pdt] subset: goslim_generic subset: goslim_prokaryote is_a: GO:0140640 ! catalytic activity, acting on a nucleic acid intersection_of: GO:0003824 ! catalytic activity intersection_of: has_primary_input CHEBI:33697 ! ribonucleic acid relationship: has_primary_input CHEBI:33697 ! ribonucleic acid property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/14225" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/21612" xsd:anyURI created_by: pg creation_date: 2017-09-14T12:05:21Z [Term] id: GO:0140103 name: catalytic activity, acting on a glycoprotein namespace: molecular_function def: "Catalysis of a biochemical reaction at physiological temperatures in which one of the substrates is a glycoprotein." [GOC:molecular_function_refactoring, GOC:pdt] is_a: GO:0003824 ! catalytic activity intersection_of: GO:0003824 ! catalytic activity intersection_of: has_primary_input CHEBI:17089 ! glycoprotein relationship: has_primary_input CHEBI:17089 ! glycoprotein property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/14225" xsd:anyURI created_by: pg creation_date: 2017-09-15T19:27:54Z [Term] id: GO:0140112 name: extracellular vesicle biogenesis namespace: biological_process def: "The assembly and secretion a set of components to form an extracellular vesicule, a membrane-bounded vesicle that is released into the extracellular region. Extracellular vesicles include exosomes, microvesicles and apoptotic bodies, based on the mechanism by which they are released from cells and differentiated based on their size and content." [PMID:28736435] synonym: "extracellular vesicle assembly" EXACT [] is_a: GO:0044085 ! cellular component biogenesis property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/14256" xsd:anyURI created_by: pg creation_date: 2017-10-23T11:53:42Z [Term] id: GO:0140236 name: translation at presynapse namespace: biological_process def: "Translation that occurs at the presynapse." [PMID:27321671] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0140241 ! translation at synapse intersection_of: GO:0006412 ! translation intersection_of: occurs_in GO:0098793 ! presynapse relationship: occurs_in GO:0098793 ! presynapse property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/216" xsd:anyURI created_by: pg creation_date: 2018-07-13T13:00:33Z [Term] id: GO:0140237 name: translation at presynapse, modulating chemical synaptic transmission namespace: biological_process def: "Translation that occurs at the presynapse, and that modulates chemical synaptic transmission." [PMID:27321671] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0140236 ! translation at presynapse intersection_of: GO:0006412 ! translation intersection_of: occurs_in GO:0098793 ! presynapse intersection_of: regulates GO:0007268 ! chemical synaptic transmission relationship: regulates GO:0007268 ! chemical synaptic transmission property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/216" xsd:anyURI created_by: pg creation_date: 2018-07-13T13:07:23Z [Term] id: GO:0140238 name: presynaptic endocytosis namespace: biological_process def: "A vesicle-mediated transport process in which the presynapse take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle." [PMID:24719103] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0006897 ! endocytosis is_a: GO:0051649 ! establishment of localization in cell is_a: GO:0099003 ! vesicle-mediated transport in synapse intersection_of: GO:0006897 ! endocytosis intersection_of: occurs_in GO:0098793 ! presynapse relationship: occurs_in GO:0098793 ! presynapse property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/230" xsd:anyURI created_by: pg creation_date: 2018-07-15T07:33:55Z [Term] id: GO:0140239 name: postsynaptic endocytosis namespace: biological_process def: "A vesicle-mediated transport process in which the postsynapse take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle." [PMID:12839988] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0006897 ! endocytosis is_a: GO:0051649 ! establishment of localization in cell is_a: GO:0099003 ! vesicle-mediated transport in synapse intersection_of: GO:0006897 ! endocytosis intersection_of: occurs_in GO:0098794 ! postsynapse relationship: occurs_in GO:0098794 ! postsynapse property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/230" xsd:anyURI created_by: pg creation_date: 2018-07-15T07:38:27Z [Term] id: GO:0140241 name: translation at synapse namespace: biological_process def: "Translation that occurs at the synapse." [PMID:23083742] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0006412 ! translation intersection_of: GO:0006412 ! translation intersection_of: occurs_in GO:0045202 ! synapse relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: occurs_in GO:0045202 ! synapse relationship: only_in_taxon NCBITaxon:33208 ! Metazoa property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/210" xsd:anyURI created_by: pg creation_date: 2018-07-15T09:23:12Z [Term] id: GO:0140242 name: translation at postsynapse namespace: biological_process def: "Translation that occurs at the postsynapse." [PMID:20427644] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0140241 ! translation at synapse intersection_of: GO:0006412 ! translation intersection_of: occurs_in GO:0098794 ! postsynapse relationship: occurs_in GO:0098794 ! postsynapse property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/210" xsd:anyURI created_by: pg creation_date: 2018-07-15T09:26:27Z [Term] id: GO:0140243 name: regulation of translation at synapse namespace: biological_process def: "Any process that regulates translation occurring at the synapse." [PMID:20427644] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0006417 ! regulation of translation intersection_of: GO:0065007 ! biological regulation intersection_of: occurs_in GO:0045202 ! synapse intersection_of: regulates GO:0006412 ! translation relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: occurs_in GO:0045202 ! synapse relationship: only_in_taxon NCBITaxon:33208 ! Metazoa property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/210" xsd:anyURI created_by: pg creation_date: 2018-07-15T09:38:26Z [Term] id: GO:0140244 name: regulation of translation at presynapse namespace: biological_process def: "Any process that regulates translation occurring at the presynapse." [PMID:20427644] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0140243 ! regulation of translation at synapse intersection_of: GO:0065007 ! biological regulation intersection_of: occurs_in GO:0098793 ! presynapse intersection_of: regulates GO:0006412 ! translation relationship: occurs_in GO:0098793 ! presynapse property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/210" xsd:anyURI created_by: pg creation_date: 2018-07-15T09:38:33Z [Term] id: GO:0140245 name: regulation of translation at postsynapse namespace: biological_process def: "Any process that regulates translation occurring at the postsynapse." [PMID:20427644] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0140243 ! regulation of translation at synapse intersection_of: GO:0065007 ! biological regulation intersection_of: occurs_in GO:0098794 ! postsynapse intersection_of: regulates GO:0006412 ! translation relationship: occurs_in GO:0098794 ! postsynapse property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/210" xsd:anyURI created_by: pg creation_date: 2018-07-15T09:38:54Z [Term] id: GO:0140246 name: protein catabolic process at synapse namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of a protein at a synapse." [PMID:17062563] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0009057 ! macromolecule catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:36080 ! protein intersection_of: occurs_in GO:0045202 ! synapse relationship: has_primary_input CHEBI:36080 ! protein relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: occurs_in GO:0045202 ! synapse relationship: only_in_taxon NCBITaxon:33208 ! Metazoa property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/210" xsd:anyURI created_by: pg creation_date: 2018-07-15T10:12:51Z [Term] id: GO:0140247 name: protein catabolic process at presynapse namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of a protein at a presynapse." [PMID:27764673] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0140246 ! protein catabolic process at synapse intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:36080 ! protein intersection_of: occurs_in GO:0098793 ! presynapse relationship: occurs_in GO:0098793 ! presynapse property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/204" xsd:anyURI created_by: pg creation_date: 2018-07-15T10:23:49Z [Term] id: GO:0140249 name: protein catabolic process at postsynapse namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of a protein at a postsynapse." [PMID:17062563] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0140246 ! protein catabolic process at synapse intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:36080 ! protein intersection_of: occurs_in GO:0098794 ! postsynapse relationship: occurs_in GO:0098794 ! postsynapse property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/204" xsd:anyURI created_by: pg creation_date: 2018-07-15T10:25:04Z [Term] id: GO:0140250 name: regulation protein catabolic process at synapse namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the synapse." [PMID:23083742] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0009894 ! regulation of catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: has_primary_input CHEBI:36080 ! protein intersection_of: occurs_in GO:0045202 ! synapse intersection_of: regulates GO:0009056 ! catabolic process relationship: has_primary_input CHEBI:36080 ! protein relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: occurs_in GO:0045202 ! synapse relationship: only_in_taxon NCBITaxon:33208 ! Metazoa property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/204" xsd:anyURI created_by: pg creation_date: 2018-07-15T10:34:56Z [Term] id: GO:0140251 name: regulation protein catabolic process at presynapse namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the presynapse." [PMID:27764673] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0140250 ! regulation protein catabolic process at synapse intersection_of: GO:0065007 ! biological regulation intersection_of: has_primary_input CHEBI:36080 ! protein intersection_of: occurs_in GO:0098793 ! presynapse intersection_of: regulates GO:0009056 ! catabolic process relationship: occurs_in GO:0098793 ! presynapse property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/204" xsd:anyURI created_by: pg creation_date: 2018-07-15T10:35:39Z [Term] id: GO:0140252 name: regulation protein catabolic process at postsynapse namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the postsynapse." [PMID:17062563] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0140250 ! regulation protein catabolic process at synapse intersection_of: GO:0065007 ! biological regulation intersection_of: has_primary_input CHEBI:36080 ! protein intersection_of: occurs_in GO:0098794 ! postsynapse intersection_of: regulates GO:0009056 ! catabolic process relationship: occurs_in GO:0098794 ! postsynapse property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/204" xsd:anyURI created_by: pg creation_date: 2018-07-15T10:35:56Z [Term] id: GO:0140253 name: cell-cell fusion namespace: biological_process def: "A cellular process in which two or more cells combine together, their plasma membrane fusing, producing a single cell. In some cases, nuclei fuse, producing a polyploid cell, while in other cases, nuclei remain separate, producing a syncytium." [Wikipedia:Cell_fusion] synonym: "cell cell fusion" EXACT [] synonym: "cell fusion" BROAD [] is_a: GO:0009987 ! cellular process relationship: has_part GO:0045026 ! plasma membrane fusion property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/15939" xsd:anyURI created_by: pg creation_date: 2018-08-13T18:38:18Z [Term] id: GO:0140318 name: protein transporter activity namespace: molecular_function def: "Directly binding to a specific protein and delivering it to a specific cellular location." [PMID:18706423] comment: Examples of protein carriers include the soluble TIM chaperone complexes of S. cerevisiae Tim9-Tim10 and Tim8-Tim13, that provide a shuttle system between TOM and the membrane insertases TIM22 and SAM and, thus, ensure that precursors are kept in a translocation-competent conformation. synonym: "protein carrier activity" RELATED [] synonym: "protein transport chaperone" RELATED [] xref: Reactome:R-HSA-9662747 "iRHOM2 transports ADAM17 from ER to the Golgi-network" xref: Reactome:R-HSA-9662818 "iRHOM2 transports ADAM17:Zn2+ from Golgi to the plasma membrane" is_a: GO:0005215 ! transporter activity intersection_of: GO:0005215 ! transporter activity intersection_of: has_primary_input PR:000000001 ! protein relationship: has_primary_input PR:000000001 ! protein property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/17073" xsd:anyURI created_by: pg creation_date: 2019-04-01T10:41:38Z [Term] id: GO:0140352 name: export from cell namespace: biological_process def: "The directed movement of some substance from a cell, into the extracellular region. This may occur via transport across the plasma membrane or via exocytosis." [GOC:pg] synonym: "efflux" BROAD [] is_a: GO:0006810 ! transport is_a: GO:0009987 ! cellular process intersection_of: GO:0006810 ! transport intersection_of: has_target_end_location GO:0005576 ! extracellular region intersection_of: has_target_start_location GO:0005622 ! intracellular anatomical structure relationship: has_target_end_location GO:0005576 ! extracellular region relationship: has_target_start_location GO:0005622 ! intracellular anatomical structure created_by: pg creation_date: 2019-05-22T11:20:45Z [Term] id: GO:0140353 name: lipid export from cell namespace: biological_process def: "The directed movement of a lipid from a cell, into the extracellular region." [GOC:pg] synonym: "lipid efflux" BROAD [] is_a: GO:0006869 ! lipid transport is_a: GO:0140352 ! export from cell intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:18059 ! lipid intersection_of: has_target_end_location GO:0005576 ! extracellular region intersection_of: has_target_start_location GO:0005622 ! intracellular anatomical structure created_by: pg creation_date: 2019-05-22T11:33:07Z [Term] id: GO:0140354 name: lipid import into cell namespace: biological_process def: "The directed movement of a lipid from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis." [GOC:pg] synonym: "lipid uptake" BROAD [] is_a: GO:0006869 ! lipid transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:18059 ! lipid intersection_of: has_target_end_location GO:0005622 ! intracellular anatomical structure intersection_of: has_target_start_location GO:0005576 ! extracellular region relationship: has_target_end_location GO:0005622 ! intracellular anatomical structure relationship: has_target_start_location GO:0005576 ! extracellular region created_by: pg creation_date: 2019-05-22T11:38:15Z [Term] id: GO:0140513 name: nuclear protein-containing complex namespace: cellular_component def: "A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together in the nucleus." [GOC:pg] subset: gocheck_do_not_annotate synonym: "nuclear complex" EXACT [] is_a: GO:0032991 ! protein-containing complex intersection_of: GO:0032991 ! protein-containing complex intersection_of: part_of GO:0005634 ! nucleus relationship: part_of GO:0005634 ! nucleus created_by: pg creation_date: 2020-09-09T05:12:38Z [Term] id: GO:0140572 name: vacuole fission namespace: biological_process def: "The division of a vacuole within a cell to form two or more separate vacuoles." [PMID:19643199] is_a: GO:0048285 ! organelle fission intersection_of: GO:0048285 ! organelle fission intersection_of: results_in_fission_of GO:0005773 ! vacuole relationship: results_in_fission_of GO:0005773 ! vacuole property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/20639" xsd:anyURI created_by: pg creation_date: 2021-01-04T10:17:58Z [Term] id: GO:0140640 name: catalytic activity, acting on a nucleic acid namespace: molecular_function def: "Catalytic activity that acts to modify a nucleic acid." [GOC:pg] is_a: GO:0003824 ! catalytic activity intersection_of: GO:0003824 ! catalytic activity intersection_of: has_primary_input CHEBI:33696 ! nucleic acid relationship: has_primary_input CHEBI:33696 ! nucleic acid property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/21402" xsd:anyURI created_by: pg creation_date: 2021-05-11T06:31:07Z [Term] id: GO:0140694 name: non-membrane-bounded organelle assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form a non-membrane-bounded organelle." [PMID:28225081] synonym: "non-membrane-bounded organelle formation" EXACT [] synonym: "non-membrane-enclosed organelle assembly" EXACT [] synonym: "non-membrane-enclosed organelle formation" EXACT [] is_a: GO:0070925 ! organelle assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0043228 ! non-membrane-bounded organelle relationship: results_in_assembly_of GO:0043228 ! non-membrane-bounded organelle property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/21939" xsd:anyURI created_by: pg creation_date: 2021-08-09T15:30:06Z [Term] id: GO:0140734 name: ammonium excretion namespace: biological_process def: "The elimination of ammonium ions from an excretory cell." [PMID:25740900] synonym: "ammonia excretion" RELATED [] is_a: GO:0007588 ! excretion intersection_of: GO:0007588 ! excretion intersection_of: has_primary_input CHEBI:28938 ! ammonium relationship: has_primary_input CHEBI:28938 ! ammonium property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22368" xsd:anyURI created_by: pg creation_date: 2021-11-24T17:55:51Z [Term] id: GO:0140961 name: cellular detoxification of metal ion namespace: biological_process def: "Any process carried out at the cellular level that reduces or removes the toxicity of a metal ion." [PMID:26729300, PMID:33046888, PMID:34442707] synonym: "cellular detoxification of metal cation" EXACT [] is_a: GO:0061687 ! detoxification of inorganic compound is_a: GO:1990748 ! cellular detoxification intersection_of: GO:1990748 ! cellular detoxification intersection_of: has_primary_input CHEBI:25213 ! metal cation relationship: has_primary_input CHEBI:25213 ! metal cation created_by: pg creation_date: 2022-12-07T15:35:18Z [Term] id: GO:0150052 name: regulation of postsynapse assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of postsynapse assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynapse." [GOC:aruk, GOC:bc, PMID:16394100, PMID:16672654, PMID:28185854] subset: goslim_synapse is_a: GO:0051963 ! regulation of synapse assembly is_a: GO:0099175 ! regulation of postsynapse organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0099068 ! postsynapse assembly relationship: regulates GO:0099068 ! postsynapse assembly created_by: bc creation_date: 2018-05-08T16:38:55Z [Term] id: GO:0150063 name: visual system development namespace: biological_process def: "The process whose specific outcome is the progression of the visual system over time, from its formation to the mature structure, including the eye, parts of the central nervous system (CNS) involved in processing of visual inputs, and connecting nerve pathways." [GOC:aruk, GOC:bc, GOC:krc, PMID:15004427, PMID:20647017, PMID:22632727] synonym: "optic pathway development" RELATED [] synonym: "visual pathway development" RELATED [] is_a: GO:0048880 ! sensory system development created_by: bc creation_date: 2018-07-23T10:31:58Z [Term] id: GO:0150076 name: neuroinflammatory response namespace: biological_process def: "The immediate defensive reaction by neural vertebrate tissue to infection or injury caused by chemical or physical agents." [GOC:aruk, GOC:bc, PMID:10981966, PMID:11099416, PMID:18164423] synonym: "nerve tissue inflammatory response" EXACT [] synonym: "nervous tissue inflammatory response" EXACT [] synonym: "neural tissue inflammatory response" EXACT [] is_a: GO:0006954 ! inflammatory response created_by: bc creation_date: 2018-07-26T12:25:34Z [Term] id: GO:0150077 name: regulation of neuroinflammatory response namespace: biological_process def: "Any process that modulates the frequency, rate or extent of neuroinflammatory response." [GOC:aruk, GOC:bc, PMID:10981966, PMID:11099416, PMID:18164423] is_a: GO:0050727 ! regulation of inflammatory response intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0150076 ! neuroinflammatory response relationship: in_taxon NCBITaxon:7742 {all_only="true"} ! Vertebrata relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: regulates GO:0150076 ! neuroinflammatory response created_by: bc creation_date: 2018-07-26T12:32:18Z [Term] id: GO:0150078 name: positive regulation of neuroinflammatory response namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of neuroinflammatory response." [GOC:aruk, GOC:bc] is_a: GO:0050729 ! positive regulation of inflammatory response is_a: GO:0150077 ! regulation of neuroinflammatory response intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0150076 ! neuroinflammatory response relationship: positively_regulates GO:0150076 ! neuroinflammatory response created_by: bc creation_date: 2018-07-26T12:35:50Z [Term] id: GO:0150079 name: negative regulation of neuroinflammatory response namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of neuroinflammatory response." [GOC:aruk, GOC:bc, PMID:11099416, PMID:18164423] is_a: GO:0050728 ! negative regulation of inflammatory response is_a: GO:0150077 ! regulation of neuroinflammatory response intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0150076 ! neuroinflammatory response relationship: negatively_regulates GO:0150076 ! neuroinflammatory response created_by: bc creation_date: 2018-07-26T12:38:08Z [Term] id: GO:0150098 name: glial cell-neuron signaling namespace: biological_process def: "Cell-cell signaling that mediates the transfer of information from a glial cell to a neuron. This signaling has been shown to be mediated by various molecules, depending on which glial cells release them, and in which tissues the signaling occurs, e.g. microglial cell-derived nerve growth factor (NGF) in the retina, or microglial cell-derived superoxide ions in the cerebellum." [GOC:aruk, GOC:bc, PMID:14980203, PMID:16144764, PMID:16547515, PMID:18685038, PMID:27788368, PMID:9459440] synonym: "glia-neuron signaling" EXACT [] synonym: "glia-neuron signalling" EXACT [] synonym: "glia-neurone signaling" EXACT [] synonym: "glia-neurone signalling" EXACT [] synonym: "glial cell- neuron signalling" EXACT [] synonym: "glial cell-neurone signalling" EXACT [] synonym: "glial cell-neurone singaling" EXACT [] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: has_end_location CL:0000540 ! neuron intersection_of: has_start_location CL:0000125 ! glial cell relationship: has_end_location CL:0000540 ! neuron relationship: has_start_location CL:0000125 ! glial cell created_by: bc creation_date: 2018-12-17T12:28:09Z [Term] id: GO:0150099 name: neuron-glial cell signaling namespace: biological_process def: "Cell-cell signaling that mediates the transfer of information from a neuron to a glial cell. This signaling has been shown to be mediated by various molecules released by different types of neurons, e.g. glutamate, gamma-amino butyric acid (GABA), noradrenaline, acetylcholine, dopamine and adenosine." [GOC:aruk, GOC:bc, PMID:10195197, PMID:10196584, PMID:10377338, PMID:10493741, PMID:11356870, PMID:11399439, PMID:15252819, PMID:27788368] synonym: "neuron-glia signaling" EXACT [] synonym: "neuron-glia signalling" EXACT [] synonym: "neuron-glial cell signalling" EXACT [] synonym: "neurone-glia signaling" EXACT [] synonym: "neurone-glia signalling" EXACT [] synonym: "neurone-glial cell signaling" EXACT [] synonym: "neurone-glial cell signalling" EXACT [] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: has_end_location CL:0000125 ! glial cell intersection_of: has_start_location CL:0000540 ! neuron relationship: has_end_location CL:0000125 ! glial cell relationship: has_start_location CL:0000540 ! neuron created_by: bc creation_date: 2018-12-17T12:30:12Z [Term] id: GO:0150105 name: protein localization to cell-cell junction namespace: biological_process def: "A process in which a protein is transported to, or maintained, in a location within a cell-cell junction." [GOC:aruk, GOC:bc, PMID:26706435] is_a: GO:1902414 ! protein localization to cell junction intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0005911 ! cell-cell junction relationship: has_target_end_location GO:0005911 ! cell-cell junction created_by: bc creation_date: 2019-06-11T11:00:18Z [Term] id: GO:0150106 name: regulation of protein localization to cell-cell junction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein localization to cell-cell junction." [GOC:aruk, GOC:bc, PMID:26706435] is_a: GO:0032880 ! regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0150105 ! protein localization to cell-cell junction relationship: regulates GO:0150105 ! protein localization to cell-cell junction created_by: bc creation_date: 2019-06-11T11:17:15Z [Term] id: GO:0150107 name: positive regulation of protein localization to cell-cell junction namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein localization to cell-cell junction." [GOC:aruk, GOC:bc, PMID:26706435] is_a: GO:0150106 ! regulation of protein localization to cell-cell junction is_a: GO:1903829 ! positive regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0150105 ! protein localization to cell-cell junction relationship: positively_regulates GO:0150105 ! protein localization to cell-cell junction created_by: bc creation_date: 2019-06-11T11:23:58Z [Term] id: GO:0150111 name: regulation of transepithelial transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of transepithelial transport." [GOC:aruk, PMID:27593915] is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0070633 ! transepithelial transport relationship: regulates GO:0070633 ! transepithelial transport created_by: bc creation_date: 2019-09-15T07:16:49Z [Term] id: GO:0150119 name: negative regulation of protein localization to cell-cell junction namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell-cell junction." [GOC:aruk, GOC:bc] synonym: "negative regulation of protein localisation to cell-cell junction" EXACT [] is_a: GO:0150106 ! regulation of protein localization to cell-cell junction is_a: GO:1903828 ! negative regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0150105 ! protein localization to cell-cell junction relationship: negatively_regulates GO:0150105 ! protein localization to cell-cell junction created_by: bc creation_date: 2019-11-21T13:53:34Z [Term] id: GO:0150146 name: cell junction disassembly namespace: biological_process def: "The disaggregation of a cell junction into its constituent components." [GOC:aruk, PMID:25490267] is_a: GO:0022411 ! cellular component disassembly is_a: GO:0034330 ! cell junction organization intersection_of: GO:0022411 ! cellular component disassembly intersection_of: results_in_disassembly_of GO:0030054 ! cell junction relationship: results_in_disassembly_of GO:0030054 ! cell junction created_by: bc creation_date: 2019-12-08T11:12:13Z [Term] id: GO:0150147 name: cell-cell junction disassembly namespace: biological_process def: "The disaggregation of a cell-cell junction into its constituent components." [GOC:aruk, PMID:25490267] is_a: GO:0045216 ! cell-cell junction organization is_a: GO:0150146 ! cell junction disassembly intersection_of: GO:0022411 ! cellular component disassembly intersection_of: results_in_disassembly_of GO:0005911 ! cell-cell junction relationship: results_in_disassembly_of GO:0005911 ! cell-cell junction created_by: bc creation_date: 2019-12-08T11:16:14Z [Term] id: GO:0160038 name: somatic sensory system development namespace: biological_process def: "The process whose specific outcome is the progression of a somatic sensory system over time from its formation to the mature structure. Somatic sensory system is the sensory system for the sense of touch and pain." [PMID:25832476, PMID:31399790] synonym: "somatosensory system development" EXACT [] is_a: GO:0048880 ! sensory system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003942 ! somatosensory system relationship: results_in_development_of UBERON:0003942 ! somatosensory system created_by: rynl creation_date: 2022-07-07T16:49:26Z [Term] id: GO:0160043 name: catecholamine secretion, neurotransmission namespace: biological_process def: "The regulated release of catecholamine by a cell in which the catecholamine acts as a neurotransmitter." [PMID:10191060] is_a: GO:0007269 ! neurotransmitter secretion is_a: GO:0050432 ! catecholamine secretion intersection_of: GO:0007269 ! neurotransmitter secretion intersection_of: has_primary_input CHEBI:33567 ! catecholamine property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23804" xsd:anyURI created_by: rynl creation_date: 2022-08-17T00:36:44Z [Term] id: GO:0160093 name: chordate pharynx development namespace: biological_process def: "The process whose specific outcome is the progression of cordate pharynx over time, from its formation to the mature structure." [PMID:23020903] is_a: GO:0060465 ! pharynx development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001042 ! chordate pharynx relationship: results_in_development_of UBERON:0001042 ! chordate pharynx property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/18285" xsd:anyURI created_by: rynl creation_date: 2023-08-29T21:05:28Z [Term] id: GO:1900015 name: regulation of cytokine production involved in inflammatory response namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cytokine production involved in inflammatory response." [GOC:TermGenie] synonym: "regulation of cytokine production involved in acute inflammatory response" NARROW [GOC:TermGenie] is_a: GO:0001817 ! regulation of cytokine production intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002534 ! cytokine production involved in inflammatory response relationship: regulates GO:0002534 ! cytokine production involved in inflammatory response created_by: rph creation_date: 2012-01-11T09:34:27Z [Term] id: GO:1900016 name: negative regulation of cytokine production involved in inflammatory response namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cytokine production involved in inflammatory response." [GOC:TermGenie] synonym: "down regulation of cytokine production involved in acute inflammatory response" BROAD [GOC:TermGenie] synonym: "down regulation of cytokine production involved in inflammatory response" RELATED [GOC:TermGenie] synonym: "negative regulation of cytokine production involved in acute inflammatory response" NARROW [GOC:TermGenie] is_a: GO:0001818 ! negative regulation of cytokine production is_a: GO:1900015 ! regulation of cytokine production involved in inflammatory response intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002534 ! cytokine production involved in inflammatory response relationship: negatively_regulates GO:0002534 ! cytokine production involved in inflammatory response created_by: rph creation_date: 2012-01-11T09:34:31Z [Term] id: GO:1900017 name: positive regulation of cytokine production involved in inflammatory response namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cytokine production involved in inflammatory response." [GOC:TermGenie] synonym: "positive regulation of cytokine production involved in acute inflammatory response" NARROW [GOC:TermGenie] synonym: "up regulation of cytokine production involved in acute inflammatory response" BROAD [GOC:TermGenie] synonym: "up regulation of cytokine production involved in inflammatory response" RELATED [GOC:TermGenie] is_a: GO:0001819 ! positive regulation of cytokine production is_a: GO:1900015 ! regulation of cytokine production involved in inflammatory response intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002534 ! cytokine production involved in inflammatory response relationship: positively_regulates GO:0002534 ! cytokine production involved in inflammatory response created_by: rph creation_date: 2012-01-11T09:34:35Z [Term] id: GO:1900073 name: regulation of neuromuscular synaptic transmission namespace: biological_process def: "Any process that modulates the frequency, rate or extent of neuromuscular synaptic transmission." [GOC:kmv, GOC:TermGenie] is_a: GO:0050804 ! modulation of chemical synaptic transmission intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007274 ! neuromuscular synaptic transmission relationship: regulates GO:0007274 ! neuromuscular synaptic transmission created_by: kmv creation_date: 2012-01-26T10:14:10Z [Term] id: GO:1900074 name: negative regulation of neuromuscular synaptic transmission namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular synaptic transmission." [GOC:kmv, GOC:TermGenie] synonym: "down regulation of neuromuscular synaptic transmission" RELATED [GOC:TermGenie] synonym: "down-regulation of neuromuscular synaptic transmission" RELATED [GOC:TermGenie] synonym: "downregulation of neuromuscular synaptic transmission" RELATED [GOC:TermGenie] synonym: "inhibition of neuromuscular synaptic transmission" RELATED [GOC:TermGenie] is_a: GO:0050805 ! negative regulation of synaptic transmission is_a: GO:1900073 ! regulation of neuromuscular synaptic transmission intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007274 ! neuromuscular synaptic transmission relationship: negatively_regulates GO:0007274 ! neuromuscular synaptic transmission created_by: kmv creation_date: 2012-01-26T10:14:18Z [Term] id: GO:1900075 name: positive regulation of neuromuscular synaptic transmission namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of neuromuscular synaptic transmission." [GOC:kmv, GOC:TermGenie] synonym: "activation of neuromuscular synaptic transmission" RELATED [GOC:TermGenie] synonym: "up regulation of neuromuscular synaptic transmission" RELATED [GOC:TermGenie] synonym: "up-regulation of neuromuscular synaptic transmission" RELATED [GOC:TermGenie] synonym: "upregulation of neuromuscular synaptic transmission" RELATED [GOC:TermGenie] is_a: GO:0050806 ! positive regulation of synaptic transmission is_a: GO:1900073 ! regulation of neuromuscular synaptic transmission intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007274 ! neuromuscular synaptic transmission relationship: positively_regulates GO:0007274 ! neuromuscular synaptic transmission created_by: kmv creation_date: 2012-01-26T10:14:22Z [Term] id: GO:1900115 name: extracellular regulation of signal transduction namespace: biological_process def: "Any regulation of signal transduction that takes place in the extracellular region." [GOC:signaling, GOC:TermGenie] synonym: "regulation of signaling pathway in extracellular region" EXACT [GOC:TermGenie] synonym: "regulation of signalling pathway in extracellular region" EXACT [GOC:TermGenie] is_a: GO:0009966 ! regulation of signal transduction intersection_of: GO:0009966 ! regulation of signal transduction intersection_of: occurs_in GO:0005576 ! extracellular region relationship: occurs_in GO:0005576 ! extracellular region created_by: bf creation_date: 2012-02-22T10:21:48Z [Term] id: GO:1900116 name: extracellular negative regulation of signal transduction namespace: biological_process def: "Any negative regulation of signal transduction that takes place in extracellular region." [GOC:signaling, GOC:TermGenie] synonym: "down regulation of signal transduction in extracellular region" EXACT [GOC:TermGenie] synonym: "down-regulation of signal transduction in extracellular region" EXACT [GOC:TermGenie] synonym: "downregulation of signal transduction in extracellular region" EXACT [GOC:TermGenie] synonym: "extracellular inhibition of signaling pathway" NARROW [GOC:bf] synonym: "inhibition of signal transduction in extracellular region" NARROW [GOC:TermGenie] synonym: "negative regulation of signaling pathway in extracellular region" EXACT [GOC:TermGenie] synonym: "negative regulation of signalling pathway in extracellular region" EXACT [GOC:TermGenie] is_a: GO:0009968 ! negative regulation of signal transduction is_a: GO:1900115 ! extracellular regulation of signal transduction intersection_of: GO:0009968 ! negative regulation of signal transduction intersection_of: occurs_in GO:0005576 ! extracellular region created_by: bf creation_date: 2012-02-22T10:27:56Z [Term] id: GO:1900117 name: regulation of execution phase of apoptosis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of execution phase of apoptosis." [GOC:mtg_apoptosis, GOC:TermGenie] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0097194 ! execution phase of apoptosis relationship: regulates GO:0097194 ! execution phase of apoptosis created_by: pr creation_date: 2012-02-22T11:26:20Z [Term] id: GO:1900118 name: negative regulation of execution phase of apoptosis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of execution phase of apoptosis." [GOC:mtg_apoptosis, GOC:TermGenie] synonym: "down regulation of execution phase of apoptosis" EXACT [GOC:TermGenie] synonym: "down-regulation of execution phase of apoptosis" EXACT [GOC:TermGenie] synonym: "downregulation of execution phase of apoptosis" EXACT [GOC:TermGenie] synonym: "inhibition of execution phase of apoptosis" NARROW [GOC:TermGenie] is_a: GO:0043066 ! negative regulation of apoptotic process is_a: GO:1900117 ! regulation of execution phase of apoptosis intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0097194 ! execution phase of apoptosis relationship: negatively_regulates GO:0097194 ! execution phase of apoptosis created_by: pr creation_date: 2012-02-22T11:26:24Z [Term] id: GO:1900119 name: positive regulation of execution phase of apoptosis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of execution phase of apoptosis." [GOC:mtg_apoptosis, GOC:TermGenie] synonym: "activation of execution phase of apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of execution phase of apoptosis" EXACT [GOC:TermGenie] synonym: "up-regulation of execution phase of apoptosis" EXACT [GOC:TermGenie] synonym: "upregulation of execution phase of apoptosis" EXACT [GOC:TermGenie] is_a: GO:0043065 ! positive regulation of apoptotic process is_a: GO:1900117 ! regulation of execution phase of apoptosis intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0097194 ! execution phase of apoptosis relationship: positively_regulates GO:0097194 ! execution phase of apoptosis created_by: pr creation_date: 2012-02-22T11:26:27Z [Term] id: GO:1900125 name: regulation of hyaluronan biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of hyaluronan biosynthetic process." [GOC:TermGenie, GOC:yaf] synonym: "regulation of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "regulation of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "regulation of hyaluronan synthesis" EXACT [GOC:TermGenie] is_a: GO:0032885 ! regulation of polysaccharide biosynthetic process is_a: GO:0051171 ! regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030213 ! hyaluronan biosynthetic process relationship: regulates GO:0030213 ! hyaluronan biosynthetic process created_by: yaf creation_date: 2012-02-23T01:09:21Z [Term] id: GO:1900126 name: negative regulation of hyaluronan biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of hyaluronan biosynthetic process." [GOC:TermGenie, GOC:yaf] synonym: "down regulation of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "down regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "down regulation of hyaluronan biosynthetic process" EXACT [GOC:TermGenie] synonym: "down regulation of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "down regulation of hyaluronan synthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of hyaluronan biosynthetic process" EXACT [GOC:TermGenie] synonym: "down-regulation of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "down-regulation of hyaluronan synthesis" EXACT [GOC:TermGenie] synonym: "downregulation of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "downregulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "downregulation of hyaluronan biosynthetic process" EXACT [GOC:TermGenie] synonym: "downregulation of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "downregulation of hyaluronan synthesis" EXACT [GOC:TermGenie] synonym: "inhibition of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "inhibition of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "inhibition of hyaluronan biosynthetic process" NARROW [GOC:TermGenie] synonym: "inhibition of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "inhibition of hyaluronan synthesis" EXACT [GOC:TermGenie] synonym: "negative regulation of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "negative regulation of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "negative regulation of hyaluronan synthesis" EXACT [GOC:TermGenie] is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process is_a: GO:0045912 ! negative regulation of carbohydrate metabolic process is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process is_a: GO:1900125 ! regulation of hyaluronan biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030213 ! hyaluronan biosynthetic process relationship: negatively_regulates GO:0030213 ! hyaluronan biosynthetic process created_by: yaf creation_date: 2012-02-23T01:09:29Z [Term] id: GO:1900127 name: positive regulation of hyaluronan biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of hyaluronan biosynthetic process." [GOC:TermGenie, GOC:yaf] synonym: "activation of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "activation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "activation of hyaluronan biosynthetic process" NARROW [GOC:TermGenie] synonym: "activation of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "activation of hyaluronan synthesis" EXACT [GOC:TermGenie] synonym: "positive regulation of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "positive regulation of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "positive regulation of hyaluronan synthesis" EXACT [GOC:TermGenie] synonym: "up regulation of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "up regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "up regulation of hyaluronan biosynthetic process" EXACT [GOC:TermGenie] synonym: "up regulation of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "up regulation of hyaluronan synthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of hyaluronan biosynthetic process" EXACT [GOC:TermGenie] synonym: "up-regulation of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "up-regulation of hyaluronan synthesis" EXACT [GOC:TermGenie] synonym: "upregulation of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "upregulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "upregulation of hyaluronan biosynthetic process" EXACT [GOC:TermGenie] synonym: "upregulation of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "upregulation of hyaluronan synthesis" EXACT [GOC:TermGenie] is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process is_a: GO:0045913 ! positive regulation of carbohydrate metabolic process is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process is_a: GO:1900125 ! regulation of hyaluronan biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030213 ! hyaluronan biosynthetic process relationship: positively_regulates GO:0030213 ! hyaluronan biosynthetic process created_by: yaf creation_date: 2012-02-23T01:09:33Z [Term] id: GO:1900150 name: regulation of defense response to fungus namespace: biological_process alt_id: GO:2000072 def: "Any process that modulates the frequency, rate or extent of defense response to fungus." [GOC:dhl, GOC:TermGenie, PMID:22242006] synonym: "regulation of defence response to fungi" EXACT [GOC:TermGenie] synonym: "regulation of defence response to fungus" EXACT [GOC:TermGenie] synonym: "regulation of defense response to fungi" EXACT [GOC:TermGenie] synonym: "regulation of defense response to fungi, incompatible interaction" NARROW [GOC:obol] synonym: "regulation of defense response to fungus, incompatible interaction" NARROW [] synonym: "regulation of resistance response to pathogenic fungi" NARROW [GOC:obol] synonym: "regulation of resistance response to pathogenic fungus" NARROW [GOC:obol] synonym: "regulation of response to pathogenic fungus (incompatible interaction)" NARROW [GOC:obol] is_a: GO:0002831 ! regulation of response to biotic stimulus is_a: GO:0031347 ! regulation of defense response is_a: GO:0032101 ! regulation of response to external stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0050832 ! defense response to fungus relationship: regulates GO:0050832 ! defense response to fungus created_by: dhl creation_date: 2012-03-06T10:00:16Z [Term] id: GO:1900180 name: regulation of protein localization to nucleus namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein localization to nucleus." [GOC:TermGenie] synonym: "regulation of protein localisation to nucleus" EXACT [GOC:TermGenie] synonym: "regulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] synonym: "regulation of protein localization in nucleus" EXACT [GOC:TermGenie] is_a: GO:0032880 ! regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0034504 ! protein localization to nucleus relationship: regulates GO:0034504 ! protein localization to nucleus created_by: bf creation_date: 2012-03-12T01:23:44Z [Term] id: GO:1900181 name: negative regulation of protein localization to nucleus namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleus." [GOC:TermGenie] synonym: "down regulation of protein localisation to nucleus" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization in nucleus" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization to nucleus" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation to nucleus" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization in nucleus" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to nucleus" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation to nucleus" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization in nucleus" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to nucleus" EXACT [GOC:TermGenie] synonym: "inhibition of protein localisation to nucleus" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization in cell nucleus" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization in nucleus" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization to nucleus" NARROW [GOC:TermGenie] synonym: "negative regulation of protein localisation to nucleus" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localization in nucleus" EXACT [GOC:TermGenie] is_a: GO:1900180 ! regulation of protein localization to nucleus is_a: GO:1903828 ! negative regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0034504 ! protein localization to nucleus relationship: negatively_regulates GO:0034504 ! protein localization to nucleus created_by: bf creation_date: 2012-03-12T01:23:48Z [Term] id: GO:1900182 name: positive regulation of protein localization to nucleus namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein localization to nucleus." [GOC:TermGenie] synonym: "activation of protein localisation to nucleus" NARROW [GOC:TermGenie] synonym: "activation of protein localization in cell nucleus" NARROW [GOC:TermGenie] synonym: "activation of protein localization in nucleus" EXACT [GOC:TermGenie] synonym: "activation of protein localization to nucleus" NARROW [GOC:TermGenie] synonym: "positive regulation of protein localisation to nucleus" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localization in nucleus" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation to nucleus" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization in nucleus" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization to nucleus" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation to nucleus" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization in nucleus" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to nucleus" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation to nucleus" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization in nucleus" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to nucleus" EXACT [GOC:TermGenie] is_a: GO:1900180 ! regulation of protein localization to nucleus is_a: GO:1903829 ! positive regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0034504 ! protein localization to nucleus relationship: positively_regulates GO:0034504 ! protein localization to nucleus created_by: bf creation_date: 2012-03-12T01:23:52Z [Term] id: GO:1900193 name: regulation of oocyte maturation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of oocyte maturation." [GOC:kmv, GOC:TermGenie] is_a: GO:1903429 ! regulation of cell maturation is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001556 ! oocyte maturation relationship: regulates GO:0001556 ! oocyte maturation created_by: kmv creation_date: 2012-03-19T09:41:18Z [Term] id: GO:1900194 name: negative regulation of oocyte maturation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of oocyte maturation." [GOC:kmv, GOC:TermGenie] synonym: "down regulation of oocyte maturation" EXACT [GOC:TermGenie] synonym: "down-regulation of oocyte maturation" EXACT [GOC:TermGenie] synonym: "downregulation of oocyte maturation" EXACT [GOC:TermGenie] synonym: "inhibition of oocyte maturation" NARROW [GOC:TermGenie] is_a: GO:1900193 ! regulation of oocyte maturation is_a: GO:1903430 ! negative regulation of cell maturation is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001556 ! oocyte maturation relationship: negatively_regulates GO:0001556 ! oocyte maturation created_by: kmv creation_date: 2012-03-19T09:41:27Z [Term] id: GO:1900195 name: positive regulation of oocyte maturation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of oocyte maturation." [GOC:kmv, GOC:TermGenie] synonym: "activation of oocyte maturation" NARROW [GOC:TermGenie] synonym: "up regulation of oocyte maturation" EXACT [GOC:TermGenie] synonym: "up-regulation of oocyte maturation" EXACT [GOC:TermGenie] synonym: "upregulation of oocyte maturation" EXACT [GOC:TermGenie] is_a: GO:1900193 ! regulation of oocyte maturation is_a: GO:1903431 ! positive regulation of cell maturation is_a: GO:2000243 ! positive regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001556 ! oocyte maturation relationship: positively_regulates GO:0001556 ! oocyte maturation created_by: kmv creation_date: 2012-03-19T09:41:35Z [Term] id: GO:1900200 name: mesenchymal cell apoptotic process involved in metanephros development namespace: biological_process def: "Any mesenchymal cell apoptotic process that is involved in metanephros development." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "mesenchymal cell apoptosis involved in metanephros development" NARROW [] is_a: GO:0097152 ! mesenchymal cell apoptotic process is_a: GO:1902742 ! apoptotic process involved in development intersection_of: GO:0097152 ! mesenchymal cell apoptotic process intersection_of: part_of GO:0001656 ! metanephros development relationship: part_of GO:0001656 ! metanephros development created_by: yaf creation_date: 2012-03-21T11:58:05Z [Term] id: GO:1900204 name: apoptotic process involved in metanephric collecting duct development namespace: biological_process def: "Any apoptotic process that is involved in metanephric collecting duct development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] synonym: "type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] is_a: GO:1902742 ! apoptotic process involved in development intersection_of: GO:0006915 ! apoptotic process intersection_of: part_of GO:0072205 ! metanephric collecting duct development relationship: part_of GO:0072205 ! metanephric collecting duct development created_by: yaf creation_date: 2012-03-21T01:21:32Z [Term] id: GO:1900205 name: apoptotic process involved in metanephric nephron tubule development namespace: biological_process def: "Any apoptotic process that is involved in metanephric nephron tubule development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] synonym: "type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] is_a: GO:1902742 ! apoptotic process involved in development intersection_of: GO:0006915 ! apoptotic process intersection_of: part_of GO:0072234 ! metanephric nephron tubule development relationship: part_of GO:0072234 ! metanephric nephron tubule development created_by: yaf creation_date: 2012-03-21T01:21:45Z [Term] id: GO:1900206 name: regulation of pronephric nephron tubule development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of pronephric nephron tubule development." [GOC:TermGenie] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0039020 ! pronephric nephron tubule development relationship: regulates GO:0039020 ! pronephric nephron tubule development created_by: bf creation_date: 2012-03-22T09:23:13Z [Term] id: GO:1900207 name: negative regulation of pronephric nephron tubule development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of pronephric nephron tubule development." [GOC:bf, GOC:TermGenie, PMID:9758706] synonym: "down regulation of pronephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "down-regulation of pronephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "downregulation of pronephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "inhibition of pronephric nephron tubule development" NARROW [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:1900206 ! regulation of pronephric nephron tubule development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0039020 ! pronephric nephron tubule development relationship: negatively_regulates GO:0039020 ! pronephric nephron tubule development created_by: bf creation_date: 2012-03-22T09:23:23Z [Term] id: GO:1900211 name: regulation of mesenchymal cell apoptotic process involved in metanephros development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "regulation of mesenchymal cell apoptosis involved in metanephros development" NARROW [] is_a: GO:1904748 ! regulation of apoptotic process involved in development is_a: GO:2001053 ! regulation of mesenchymal cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1900200 ! mesenchymal cell apoptotic process involved in metanephros development relationship: regulates GO:1900200 ! mesenchymal cell apoptotic process involved in metanephros development created_by: yaf creation_date: 2012-03-22T10:52:50Z [Term] id: GO:1900212 name: negative regulation of mesenchymal cell apoptotic process involved in metanephros development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "down regulation of mesenchymal cell apoptosis involved in metanephros development" EXACT [GOC:TermGenie] synonym: "down-regulation of mesenchymal cell apoptosis involved in metanephros development" EXACT [GOC:TermGenie] synonym: "downregulation of mesenchymal cell apoptosis involved in metanephros development" EXACT [GOC:TermGenie] synonym: "inhibition of mesenchymal cell apoptosis involved in metanephros development" NARROW [GOC:TermGenie] synonym: "negative regulation of mesenchymal cell apoptosis involved in metanephros development" NARROW [] is_a: GO:1900211 ! regulation of mesenchymal cell apoptotic process involved in metanephros development is_a: GO:1904746 ! negative regulation of apoptotic process involved in development is_a: GO:2001054 ! negative regulation of mesenchymal cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1900200 ! mesenchymal cell apoptotic process involved in metanephros development relationship: negatively_regulates GO:1900200 ! mesenchymal cell apoptotic process involved in metanephros development created_by: yaf creation_date: 2012-03-22T10:53:00Z [Term] id: GO:1900213 name: positive regulation of mesenchymal cell apoptotic process involved in metanephros development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "activation of mesenchymal cell apoptosis involved in metanephros development" NARROW [GOC:TermGenie] synonym: "positive regulation of mesenchymal cell apoptosis involved in metanephros development" NARROW [] synonym: "up regulation of mesenchymal cell apoptosis involved in metanephros development" EXACT [GOC:TermGenie] synonym: "up-regulation of mesenchymal cell apoptosis involved in metanephros development" EXACT [GOC:TermGenie] synonym: "upregulation of mesenchymal cell apoptosis involved in metanephros development" EXACT [GOC:TermGenie] is_a: GO:1900211 ! regulation of mesenchymal cell apoptotic process involved in metanephros development is_a: GO:1904747 ! positive regulation of apoptotic process involved in development is_a: GO:2001055 ! positive regulation of mesenchymal cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1900200 ! mesenchymal cell apoptotic process involved in metanephros development relationship: positively_regulates GO:1900200 ! mesenchymal cell apoptotic process involved in metanephros development created_by: yaf creation_date: 2012-03-22T10:53:09Z [Term] id: GO:1900214 name: regulation of apoptotic process involved in metanephric collecting duct development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "regulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "regulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "regulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "regulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "regulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "regulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "regulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] synonym: "regulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] is_a: GO:1904748 ! regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1900204 ! apoptotic process involved in metanephric collecting duct development relationship: regulates GO:1900204 ! apoptotic process involved in metanephric collecting duct development created_by: yaf creation_date: 2012-03-22T10:53:21Z [Term] id: GO:1900215 name: negative regulation of apoptotic process involved in metanephric collecting duct development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "down regulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "down regulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic process involved in metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "down regulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "down regulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "down regulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] synonym: "down regulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic process involved in metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "down-regulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "down-regulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] synonym: "down-regulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "downregulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "downregulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic process involved in metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "downregulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "downregulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "downregulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] synonym: "downregulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "inhibition of apoptotic process involved in metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "inhibition of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "inhibition of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "inhibition of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] synonym: "inhibition of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "negative regulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "negative regulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "negative regulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "negative regulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "negative regulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "negative regulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "negative regulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] synonym: "negative regulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] is_a: GO:1900214 ! regulation of apoptotic process involved in metanephric collecting duct development is_a: GO:1904746 ! negative regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1900204 ! apoptotic process involved in metanephric collecting duct development relationship: negatively_regulates GO:1900204 ! apoptotic process involved in metanephric collecting duct development created_by: yaf creation_date: 2012-03-22T10:53:31Z [Term] id: GO:1900216 name: positive regulation of apoptotic process involved in metanephric collecting duct development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "activation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "activation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "activation of apoptotic process involved in metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "activation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "activation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "activation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "activation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "activation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] synonym: "activation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "positive regulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "positive regulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "positive regulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "positive regulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "positive regulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "positive regulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "positive regulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] synonym: "positive regulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "up regulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "up regulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic process involved in metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "up regulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "up regulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "up regulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] synonym: "up regulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic process involved in metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "up-regulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "up-regulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] synonym: "up-regulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "upregulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "upregulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic process involved in metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "upregulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "upregulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "upregulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] synonym: "upregulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] is_a: GO:1900214 ! regulation of apoptotic process involved in metanephric collecting duct development is_a: GO:1904747 ! positive regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1900204 ! apoptotic process involved in metanephric collecting duct development relationship: positively_regulates GO:1900204 ! apoptotic process involved in metanephric collecting duct development created_by: yaf creation_date: 2012-03-22T10:53:39Z [Term] id: GO:1900217 name: regulation of apoptotic process involved in metanephric nephron tubule development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "regulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "regulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "regulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "regulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "regulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "regulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "regulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] synonym: "regulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] is_a: GO:1904748 ! regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1900205 ! apoptotic process involved in metanephric nephron tubule development relationship: regulates GO:1900205 ! apoptotic process involved in metanephric nephron tubule development created_by: yaf creation_date: 2012-03-22T10:53:51Z [Term] id: GO:1900218 name: negative regulation of apoptotic process involved in metanephric nephron tubule development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "down regulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "down regulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic process involved in metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "down regulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "down regulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "down regulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] synonym: "down regulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic process involved in metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "down-regulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "down-regulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] synonym: "down-regulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "downregulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "downregulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic process involved in metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "downregulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "downregulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "downregulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] synonym: "downregulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "inhibition of apoptotic process involved in metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "inhibition of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "inhibition of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "inhibition of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] synonym: "inhibition of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "negative regulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "negative regulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "negative regulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "negative regulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "negative regulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "negative regulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "negative regulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] synonym: "negative regulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] is_a: GO:1900217 ! regulation of apoptotic process involved in metanephric nephron tubule development is_a: GO:1904746 ! negative regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1900205 ! apoptotic process involved in metanephric nephron tubule development relationship: negatively_regulates GO:1900205 ! apoptotic process involved in metanephric nephron tubule development created_by: yaf creation_date: 2012-03-22T10:54:01Z [Term] id: GO:1900219 name: positive regulation of apoptotic process involved in metanephric nephron tubule development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "activation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "activation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "activation of apoptotic process involved in metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "activation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "activation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "activation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "activation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "activation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] synonym: "activation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "positive regulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "positive regulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "positive regulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "positive regulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "positive regulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "positive regulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "positive regulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] synonym: "positive regulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "up regulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "up regulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic process involved in metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "up regulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "up regulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "up regulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] synonym: "up regulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic process involved in metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "up-regulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "up-regulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] synonym: "up-regulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "upregulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "upregulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic process involved in metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "upregulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "upregulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "upregulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] synonym: "upregulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] is_a: GO:1900217 ! regulation of apoptotic process involved in metanephric nephron tubule development is_a: GO:1904747 ! positive regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1900205 ! apoptotic process involved in metanephric nephron tubule development relationship: positively_regulates GO:1900205 ! apoptotic process involved in metanephric nephron tubule development created_by: yaf creation_date: 2012-03-22T10:54:09Z [Term] id: GO:1900366 name: negative regulation of defense response to insect namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of defense response to insect." [GOC:TermGenie, PMID:22474183] synonym: "down regulation of defense response to insect" EXACT [GOC:TermGenie] synonym: "down regulation of physiological defense response to insect" EXACT [GOC:TermGenie] synonym: "down-regulation of defense response to insect" EXACT [GOC:TermGenie] synonym: "down-regulation of physiological defense response to insect" EXACT [GOC:TermGenie] synonym: "downregulation of defense response to insect" EXACT [GOC:TermGenie] synonym: "downregulation of physiological defense response to insect" EXACT [GOC:TermGenie] synonym: "inhibition of defense response to insect" NARROW [GOC:TermGenie] synonym: "inhibition of physiological defense response to insect" NARROW [GOC:TermGenie] synonym: "negative regulation of physiological defense response to insect" EXACT [GOC:TermGenie] synonym: "susceptibility to insect" RELATED [] is_a: GO:0031348 ! negative regulation of defense response is_a: GO:2000068 ! regulation of defense response to insect intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002213 ! defense response to insect relationship: negatively_regulates GO:0002213 ! defense response to insect created_by: dhl creation_date: 2012-04-12T04:44:00Z [Term] id: GO:1900367 name: positive regulation of defense response to insect namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of defense response to insect." [GOC:TermGenie, PMID:22474183] synonym: "activation of defense response to insect" NARROW [GOC:TermGenie] synonym: "activation of physiological defense response to insect" NARROW [GOC:TermGenie] synonym: "positive regulation of physiological defense response to insect" EXACT [GOC:TermGenie] synonym: "up regulation of defense response to insect" EXACT [GOC:TermGenie] synonym: "up regulation of physiological defense response to insect" EXACT [GOC:TermGenie] synonym: "up-regulation of defense response to insect" EXACT [GOC:TermGenie] synonym: "up-regulation of physiological defense response to insect" EXACT [GOC:TermGenie] synonym: "upregulation of defense response to insect" EXACT [GOC:TermGenie] synonym: "upregulation of physiological defense response to insect" EXACT [GOC:TermGenie] is_a: GO:0031349 ! positive regulation of defense response is_a: GO:2000068 ! regulation of defense response to insect intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002213 ! defense response to insect relationship: positively_regulates GO:0002213 ! defense response to insect created_by: dhl creation_date: 2012-04-12T04:44:10Z [Term] id: GO:1900376 name: regulation of secondary metabolite biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of secondary metabolite biosynthetic process." [GOC:di, GOC:TermGenie] synonym: "regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] is_a: GO:0009889 ! regulation of biosynthetic process is_a: GO:0043455 ! regulation of secondary metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0044550 ! secondary metabolite biosynthetic process relationship: regulates GO:0044550 ! secondary metabolite biosynthetic process created_by: di creation_date: 2012-04-17T01:55:23Z [Term] id: GO:1900377 name: negative regulation of secondary metabolite biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of secondary metabolite biosynthetic process." [GOC:di, GOC:TermGenie] synonym: "down regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] synonym: "down regulation of secondary metabolite biosynthetic process" EXACT [GOC:TermGenie] synonym: "down-regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of secondary metabolite biosynthetic process" EXACT [GOC:TermGenie] synonym: "downregulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] synonym: "downregulation of secondary metabolite biosynthetic process" EXACT [GOC:TermGenie] synonym: "inhibition of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] synonym: "inhibition of secondary metabolite biosynthetic process" NARROW [GOC:TermGenie] synonym: "negative regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] is_a: GO:0009890 ! negative regulation of biosynthetic process is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0044550 ! secondary metabolite biosynthetic process relationship: negatively_regulates GO:0044550 ! secondary metabolite biosynthetic process created_by: di creation_date: 2012-04-17T01:55:32Z [Term] id: GO:1900378 name: positive regulation of secondary metabolite biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of secondary metabolite biosynthetic process." [GOC:di, GOC:TermGenie] synonym: "activation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] synonym: "activation of secondary metabolite biosynthetic process" NARROW [GOC:TermGenie] synonym: "positive regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] synonym: "up regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] synonym: "up regulation of secondary metabolite biosynthetic process" EXACT [GOC:TermGenie] synonym: "up-regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of secondary metabolite biosynthetic process" EXACT [GOC:TermGenie] synonym: "upregulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] synonym: "upregulation of secondary metabolite biosynthetic process" EXACT [GOC:TermGenie] is_a: GO:0009891 ! positive regulation of biosynthetic process is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0044550 ! secondary metabolite biosynthetic process relationship: positively_regulates GO:0044550 ! secondary metabolite biosynthetic process created_by: di creation_date: 2012-04-17T01:55:41Z [Term] id: GO:1900424 name: regulation of defense response to bacterium namespace: biological_process alt_id: GO:1902477 def: "Any process that modulates the frequency, rate or extent of defense response to bacterium." [GOC:TermGenie, PMID:22346749] synonym: "regulation of antibacterial peptide activity" RELATED [GOC:TermGenie] synonym: "regulation of defence response to bacteria" EXACT [GOC:TermGenie] synonym: "regulation of defence response to bacterium" EXACT [GOC:TermGenie] synonym: "regulation of defence response to bacterium, incompatible interaction" NARROW [GOC:TermGenie] synonym: "regulation of defence response to pathogenic bacteria, incompatible interaction" NARROW [GOC:TermGenie] synonym: "regulation of defence response to pathogenic bacterium, incompatible interaction" NARROW [GOC:TermGenie] synonym: "regulation of defense response to bacteria" EXACT [GOC:TermGenie] synonym: "regulation of defense response to bacterium, incompatible interaction" NARROW [] synonym: "regulation of resistance response to pathogenic bacteria" NARROW [GOC:TermGenie] synonym: "regulation of resistance response to pathogenic bacterium" NARROW [GOC:TermGenie] is_a: GO:0002831 ! regulation of response to biotic stimulus is_a: GO:0031347 ! regulation of defense response is_a: GO:0032101 ! regulation of response to external stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0042742 ! defense response to bacterium relationship: regulates GO:0042742 ! defense response to bacterium created_by: dhl creation_date: 2012-04-24T10:12:43Z [Term] id: GO:1900425 name: negative regulation of defense response to bacterium namespace: biological_process alt_id: GO:1902478 def: "Any process that stops, prevents or reduces the frequency, rate or extent of defense response to bacterium." [GOC:TermGenie, PMID:22346749] synonym: "down regulation of antibacterial peptide activity" RELATED [GOC:TermGenie] synonym: "down regulation of defence response to bacteria" EXACT [GOC:TermGenie] synonym: "down regulation of defence response to bacterium" EXACT [GOC:TermGenie] synonym: "down regulation of defense response to bacteria" EXACT [GOC:TermGenie] synonym: "down regulation of defense response to bacterium" EXACT [GOC:TermGenie] synonym: "down-regulation of antibacterial peptide activity" RELATED [GOC:TermGenie] synonym: "down-regulation of defence response to bacteria" EXACT [GOC:TermGenie] synonym: "down-regulation of defence response to bacterium" EXACT [GOC:TermGenie] synonym: "down-regulation of defense response to bacteria" EXACT [GOC:TermGenie] synonym: "down-regulation of defense response to bacterium" EXACT [GOC:TermGenie] synonym: "downregulation of antibacterial peptide activity" RELATED [GOC:TermGenie] synonym: "downregulation of defence response to bacteria" EXACT [GOC:TermGenie] synonym: "downregulation of defence response to bacterium" EXACT [GOC:TermGenie] synonym: "downregulation of defense response to bacteria" EXACT [GOC:TermGenie] synonym: "downregulation of defense response to bacterium" EXACT [GOC:TermGenie] synonym: "inhibition of antibacterial peptide activity" RELATED [GOC:TermGenie] synonym: "inhibition of defence response to bacteria" EXACT [GOC:TermGenie] synonym: "inhibition of defence response to bacterium" EXACT [GOC:TermGenie] synonym: "inhibition of defence response to pathogenic bacteria, incompatible interaction" NARROW [GOC:TermGenie] synonym: "inhibition of defence response to pathogenic bacterium, incompatible interaction" NARROW [GOC:TermGenie] synonym: "inhibition of defense response to bacteria" EXACT [GOC:TermGenie] synonym: "inhibition of defense response to bacterium" NARROW [GOC:TermGenie] synonym: "inhibition of defense response to bacterium, incompatible interaction" NARROW [GOC:TermGenie] synonym: "inhibition of resistance response to pathogenic bacteria" NARROW [GOC:TermGenie] synonym: "inhibition of resistance response to pathogenic bacterium" NARROW [GOC:TermGenie] synonym: "inhibition of response to pathogenic bacteria (incompatible interaction)" NARROW [GOC:TermGenie] synonym: "inhibition of response to pathogenic bacterium (incompatible interaction)" NARROW [GOC:TermGenie] synonym: "negative regulation of antibacterial peptide activity" RELATED [GOC:TermGenie] synonym: "negative regulation of defence response to bacteria" EXACT [GOC:TermGenie] synonym: "negative regulation of defence response to bacterium" EXACT [GOC:TermGenie] synonym: "negative regulation of defense response to bacteria" EXACT [GOC:TermGenie] synonym: "negative regulation of defense response to bacterium, incompatible interaction" NARROW [] is_a: GO:0002832 ! negative regulation of response to biotic stimulus is_a: GO:0031348 ! negative regulation of defense response is_a: GO:0032102 ! negative regulation of response to external stimulus is_a: GO:1900424 ! regulation of defense response to bacterium intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0042742 ! defense response to bacterium relationship: negatively_regulates GO:0042742 ! defense response to bacterium created_by: dhl creation_date: 2012-04-24T10:12:54Z [Term] id: GO:1900426 name: positive regulation of defense response to bacterium namespace: biological_process alt_id: GO:1902479 def: "Any process that activates or increases the frequency, rate or extent of defense response to bacterium." [GOC:TermGenie, PMID:22346749] synonym: "activation of antibacterial peptide activity" RELATED [GOC:TermGenie] synonym: "activation of defence response to bacteria" EXACT [GOC:TermGenie] synonym: "activation of defence response to bacterium" EXACT [GOC:TermGenie] synonym: "activation of defense response to bacteria" EXACT [GOC:TermGenie] synonym: "activation of defense response to bacterium" NARROW [GOC:TermGenie] synonym: "activation of resistance response to pathogenic bacteria" NARROW [GOC:TermGenie] synonym: "activation of resistance response to pathogenic bacterium" NARROW [GOC:TermGenie] synonym: "positive regulation of antibacterial peptide activity" RELATED [GOC:TermGenie] synonym: "positive regulation of defence response to bacteria" EXACT [GOC:TermGenie] synonym: "positive regulation of defence response to bacterium" EXACT [GOC:TermGenie] synonym: "positive regulation of defense response to bacteria" EXACT [GOC:TermGenie] synonym: "positive regulation of defense response to bacterium, incompatible interaction" NARROW [] synonym: "up regulation of antibacterial peptide activity" RELATED [GOC:TermGenie] synonym: "up regulation of defence response to bacteria" EXACT [GOC:TermGenie] synonym: "up regulation of defence response to bacterium" EXACT [GOC:TermGenie] synonym: "up regulation of defense response to bacteria" EXACT [GOC:TermGenie] synonym: "up regulation of defense response to bacterium" EXACT [GOC:TermGenie] synonym: "up-regulation of antibacterial peptide activity" RELATED [GOC:TermGenie] synonym: "up-regulation of defence response to bacteria" EXACT [GOC:TermGenie] synonym: "up-regulation of defence response to bacterium" EXACT [GOC:TermGenie] synonym: "up-regulation of defense response to bacteria" EXACT [GOC:TermGenie] synonym: "up-regulation of defense response to bacterium" EXACT [GOC:TermGenie] synonym: "upregulation of antibacterial peptide activity" RELATED [GOC:TermGenie] synonym: "upregulation of defence response to bacteria" EXACT [GOC:TermGenie] synonym: "upregulation of defence response to bacterium" EXACT [GOC:TermGenie] synonym: "upregulation of defense response to bacteria" EXACT [GOC:TermGenie] synonym: "upregulation of defense response to bacterium" EXACT [GOC:TermGenie] is_a: GO:0002833 ! positive regulation of response to biotic stimulus is_a: GO:0031349 ! positive regulation of defense response is_a: GO:0032103 ! positive regulation of response to external stimulus is_a: GO:1900424 ! regulation of defense response to bacterium intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0042742 ! defense response to bacterium relationship: positively_regulates GO:0042742 ! defense response to bacterium created_by: dhl creation_date: 2012-04-24T10:13:13Z [Term] id: GO:1900619 name: acetate ester metabolic process namespace: biological_process def: "The chemical reactions and pathways involving an acetate ester, any carboxylic ester where the carboxylic acid component is acetic acid." [GOC:TermGenie] synonym: "acetate ester metabolism" EXACT [GOC:TermGenie] synonym: "acetyl ester metabolic process" EXACT [CHEBI:47622] synonym: "acetyl ester metabolism" EXACT [CHEBI:47622] is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:47622 ! acetate ester relationship: has_primary_input_or_output CHEBI:47622 ! acetate ester created_by: bf creation_date: 2012-05-16T12:29:51Z [Term] id: GO:1900620 name: acetate ester biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of an acetate esteran acetate ester, any carboxylic ester where the carboxylic acid component is acetic acid." [GOC:TermGenie, PMID:15042596] synonym: "acetate ester anabolism" EXACT [GOC:TermGenie] synonym: "acetate ester biosynthesis" EXACT [GOC:TermGenie] synonym: "acetate ester formation" EXACT [GOC:TermGenie] synonym: "acetate ester synthesis" EXACT [GOC:TermGenie] synonym: "acetyl ester biosynthesis" EXACT [CHEBI:47622] synonym: "acetyl ester biosynthetic process" EXACT [CHEBI:47622] is_a: GO:1900619 ! acetate ester metabolic process is_a: GO:1901576 ! organic substance biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:47622 ! acetate ester relationship: has_primary_output CHEBI:47622 ! acetate ester created_by: bf creation_date: 2012-05-16T12:30:12Z [Term] id: GO:1901071 name: glucosamine-containing compound metabolic process namespace: biological_process def: "The chemical reactions and pathways involving glucosamine-containing compounds (glucosamines)." [GOC:TermGenie] synonym: "glucosamine-containing compound metabolism" EXACT [GOC:bf] synonym: "glucosamines metabolic process" EXACT [CHEBI:24271] synonym: "glucosamines metabolism" EXACT [GOC:TermGenie] is_a: GO:0006040 ! amino sugar metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:24271 ! glucosamines relationship: has_primary_input_or_output CHEBI:24271 ! glucosamines created_by: bf creation_date: 2012-07-02T03:18:04Z [Term] id: GO:1901072 name: glucosamine-containing compound catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of glucosamine-containing compounds (glucosamines)." [GOC:TermGenie] synonym: "glucosamine-containing compound breakdown" EXACT [GOC:bf] synonym: "glucosamine-containing compound catabolism" EXACT [GOC:bf] synonym: "glucosamine-containing compound degradation" EXACT [GOC:bf] synonym: "glucosamines breakdown" EXACT [GOC:TermGenie] synonym: "glucosamines catabolic process" EXACT [CHEBI:24271] synonym: "glucosamines catabolism" EXACT [GOC:TermGenie] synonym: "glucosamines degradation" EXACT [GOC:TermGenie] is_a: GO:0046348 ! amino sugar catabolic process is_a: GO:1901071 ! glucosamine-containing compound metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:24271 ! glucosamines relationship: has_primary_input CHEBI:24271 ! glucosamines created_by: bf creation_date: 2012-07-02T03:18:25Z [Term] id: GO:1901073 name: glucosamine-containing compound biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of glucosamine-containing compounds (glucosamines)." [GOC:TermGenie] synonym: "glucosamine-containing compound anabolism" EXACT [GOC:bf] synonym: "glucosamine-containing compound biosynthesis" EXACT [GOC:bf] synonym: "glucosamine-containing compound formation" EXACT [GOC:bf] synonym: "glucosamine-containing compound synthesis" EXACT [GOC:bf] synonym: "glucosamines anabolism" EXACT [GOC:TermGenie] synonym: "glucosamines biosynthesis" EXACT [GOC:TermGenie] synonym: "glucosamines biosynthetic process" EXACT [CHEBI:24271] synonym: "glucosamines formation" EXACT [GOC:TermGenie] synonym: "glucosamines synthesis" EXACT [GOC:TermGenie] is_a: GO:0046349 ! amino sugar biosynthetic process is_a: GO:1901071 ! glucosamine-containing compound metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:24271 ! glucosamines relationship: has_primary_output CHEBI:24271 ! glucosamines created_by: bf creation_date: 2012-07-02T03:18:33Z [Term] id: GO:1901135 name: carbohydrate derivative metabolic process namespace: biological_process def: "The chemical reactions and pathways involving carbohydrate derivative." [GOC:TermGenie] subset: goslim_agr subset: goslim_generic subset: goslim_mouse subset: goslim_prokaryote synonym: "carbohydrate derivative metabolism" EXACT [GOC:TermGenie] is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:63299 ! carbohydrate derivative relationship: has_primary_input_or_output CHEBI:63299 ! carbohydrate derivative created_by: bf creation_date: 2012-07-12T04:05:09Z [Term] id: GO:1901136 name: carbohydrate derivative catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of carbohydrate derivative." [GOC:TermGenie] synonym: "carbohydrate derivative breakdown" EXACT [GOC:TermGenie] synonym: "carbohydrate derivative catabolism" EXACT [GOC:TermGenie] synonym: "carbohydrate derivative degradation" EXACT [GOC:TermGenie] is_a: GO:1901135 ! carbohydrate derivative metabolic process is_a: GO:1901575 ! organic substance catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:63299 ! carbohydrate derivative relationship: has_primary_input CHEBI:63299 ! carbohydrate derivative created_by: bf creation_date: 2012-07-12T04:05:31Z [Term] id: GO:1901137 name: carbohydrate derivative biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of carbohydrate derivative." [GOC:TermGenie] synonym: "carbohydrate derivative anabolism" EXACT [GOC:TermGenie] synonym: "carbohydrate derivative biosynthesis" EXACT [GOC:TermGenie] synonym: "carbohydrate derivative formation" EXACT [GOC:TermGenie] synonym: "carbohydrate derivative synthesis" EXACT [GOC:TermGenie] is_a: GO:1901135 ! carbohydrate derivative metabolic process is_a: GO:1901576 ! organic substance biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:63299 ! carbohydrate derivative relationship: has_primary_output CHEBI:63299 ! carbohydrate derivative created_by: bf creation_date: 2012-07-12T04:05:39Z [Term] id: GO:1901142 name: insulin metabolic process namespace: biological_process def: "The chemical reactions and pathways involving insulin." [GOC:TermGenie] synonym: "insulin metabolism" EXACT [GOC:TermGenie] is_a: GO:0019538 ! protein metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output PR:000009054 ! insulin gene translation product relationship: has_primary_input_or_output PR:000009054 ! insulin gene translation product property_value: RO:0002161 NCBITaxon:33090 property_value: RO:0002161 NCBITaxon_Union:0000023 created_by: pm creation_date: 2012-07-13T12:32:40Z [Term] id: GO:1901143 name: insulin catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of insulin." [GOC:TermGenie] synonym: "insulin breakdown" EXACT [GOC:TermGenie] synonym: "insulin catabolism" EXACT [GOC:TermGenie] synonym: "insulin degradation" EXACT [GOC:TermGenie] is_a: GO:0030163 ! protein catabolic process is_a: GO:1901142 ! insulin metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input PR:000009054 ! insulin gene translation product relationship: has_primary_input PR:000009054 ! insulin gene translation product created_by: pm creation_date: 2012-07-13T12:33:03Z [Term] id: GO:1901145 name: mesenchymal cell apoptotic process involved in nephron morphogenesis namespace: biological_process def: "Any mesenchymal cell apoptotic process that is involved in nephron morphogenesis." [GOC:mtg_apoptosis, GOC:TermGenie] is_a: GO:0060561 ! apoptotic process involved in morphogenesis is_a: GO:0097152 ! mesenchymal cell apoptotic process intersection_of: GO:0097152 ! mesenchymal cell apoptotic process intersection_of: part_of GO:0072028 ! nephron morphogenesis relationship: part_of GO:0072028 ! nephron morphogenesis created_by: pr creation_date: 2012-07-13T01:43:51Z [Term] id: GO:1901146 name: mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis namespace: biological_process def: "Any mesenchymal cell apoptotic process that is involved in mesonephric nephron morphogenesis." [GOC:mtg_apoptosis, GOC:TermGenie] is_a: GO:1901145 ! mesenchymal cell apoptotic process involved in nephron morphogenesis intersection_of: GO:0097152 ! mesenchymal cell apoptotic process intersection_of: part_of GO:0061228 ! mesonephric nephron morphogenesis relationship: part_of GO:0061228 ! mesonephric nephron morphogenesis created_by: pr creation_date: 2012-07-13T02:40:43Z [Term] id: GO:1901147 name: mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis namespace: biological_process def: "Any mesenchymal cell apoptotic process that is involved in metanephric nephron morphogenesis." [GOC:mtg_apoptosis, GOC:TermGenie] is_a: GO:1900200 ! mesenchymal cell apoptotic process involved in metanephros development is_a: GO:1901145 ! mesenchymal cell apoptotic process involved in nephron morphogenesis intersection_of: GO:0097152 ! mesenchymal cell apoptotic process intersection_of: part_of GO:0072273 ! metanephric nephron morphogenesis relationship: part_of GO:0072273 ! metanephric nephron morphogenesis created_by: pr creation_date: 2012-07-13T02:41:12Z [Term] id: GO:1901148 name: gene expression involved in extracellular matrix organization namespace: biological_process def: "Any gene expression that is involved in extracellular matrix organization. Gene expression includes both transcription to produce an RNA transcript, and the translation of that mRNA into protein. Protein maturation is included in gene expression when required to form an active form of a product from an inactive precursor form." [GOC:pg, GOC:TermGenie, PMID:18668558] synonym: "expression of extracellular matrix proteins" EXACT [GOC:bf] synonym: "extracellular matrix protein production" RELATED [GOC:pg] is_a: GO:0010467 ! gene expression intersection_of: GO:0010467 ! gene expression intersection_of: part_of GO:0030198 ! extracellular matrix organization relationship: part_of GO:0030198 ! extracellular matrix organization created_by: bf creation_date: 2012-07-16T03:29:30Z [Term] id: GO:1901160 name: primary amino compound metabolic process namespace: biological_process def: "The chemical reactions and pathways involving primary amino compound." [GOC:TermGenie] synonym: "primary amino compound metabolism" EXACT [GOC:TermGenie] is_a: GO:1901564 ! organonitrogen compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:50994 ! primary amino compound relationship: has_primary_input_or_output CHEBI:50994 ! primary amino compound created_by: bf creation_date: 2012-07-18T04:44:39Z [Term] id: GO:1901161 name: primary amino compound catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of primary amino compound." [GOC:TermGenie] synonym: "primary amino compound breakdown" EXACT [GOC:TermGenie] synonym: "primary amino compound catabolism" EXACT [GOC:TermGenie] synonym: "primary amino compound degradation" EXACT [GOC:TermGenie] is_a: GO:1901160 ! primary amino compound metabolic process is_a: GO:1901565 ! organonitrogen compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:50994 ! primary amino compound relationship: has_primary_input CHEBI:50994 ! primary amino compound created_by: bf creation_date: 2012-07-18T04:45:06Z [Term] id: GO:1901162 name: primary amino compound biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of primary amino compound." [GOC:TermGenie] synonym: "primary amino compound anabolism" EXACT [GOC:TermGenie] synonym: "primary amino compound biosynthesis" EXACT [GOC:TermGenie] synonym: "primary amino compound formation" EXACT [GOC:TermGenie] synonym: "primary amino compound synthesis" EXACT [GOC:TermGenie] is_a: GO:1901160 ! primary amino compound metabolic process is_a: GO:1901566 ! organonitrogen compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:50994 ! primary amino compound relationship: has_primary_output CHEBI:50994 ! primary amino compound created_by: bf creation_date: 2012-07-18T04:45:14Z [Term] id: GO:1901163 name: regulation of trophoblast cell migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of trophoblast cell migration." [GOC:BHF, GOC:TermGenie] is_a: GO:0030334 ! regulation of cell migration is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0061450 ! trophoblast cell migration relationship: regulates GO:0061450 ! trophoblast cell migration created_by: vk creation_date: 2012-07-19T07:53:06Z [Term] id: GO:1901164 name: negative regulation of trophoblast cell migration namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of trophoblast cell migration." [GOC:BHF, GOC:TermGenie] synonym: "down regulation of trophoblast cell migration" EXACT [GOC:TermGenie] synonym: "down-regulation of trophoblast cell migration" EXACT [GOC:TermGenie] synonym: "downregulation of trophoblast cell migration" EXACT [GOC:TermGenie] synonym: "inhibition of trophoblast cell migration" NARROW [GOC:TermGenie] is_a: GO:0030336 ! negative regulation of cell migration is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1901163 ! regulation of trophoblast cell migration is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0061450 ! trophoblast cell migration relationship: negatively_regulates GO:0061450 ! trophoblast cell migration created_by: vk creation_date: 2012-07-19T07:53:28Z [Term] id: GO:1901165 name: positive regulation of trophoblast cell migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of trophoblast cell migration." [GOC:BHF, GOC:TermGenie] synonym: "activation of trophoblast cell migration" NARROW [GOC:TermGenie] synonym: "up regulation of trophoblast cell migration" EXACT [GOC:TermGenie] synonym: "up-regulation of trophoblast cell migration" EXACT [GOC:TermGenie] synonym: "upregulation of trophoblast cell migration" EXACT [GOC:TermGenie] is_a: GO:0030335 ! positive regulation of cell migration is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1901163 ! regulation of trophoblast cell migration is_a: GO:2000243 ! positive regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0061450 ! trophoblast cell migration relationship: positively_regulates GO:0061450 ! trophoblast cell migration created_by: vk creation_date: 2012-07-19T07:53:35Z [Term] id: GO:1901166 name: neural crest cell migration involved in autonomic nervous system development namespace: biological_process def: "Any neural crest cell migration that is involved in autonomic nervous system development." [GOC:BHF, GOC:TermGenie] is_a: GO:0001755 ! neural crest cell migration intersection_of: GO:0001755 ! neural crest cell migration intersection_of: part_of GO:0048483 ! autonomic nervous system development relationship: part_of GO:0048483 ! autonomic nervous system development created_by: vk creation_date: 2012-07-19T08:39:56Z [Term] id: GO:1901190 name: regulation of formation of translation initiation ternary complex namespace: biological_process def: "Any process that modulates the frequency, rate or extent of formation of translation initiation ternary complex." [GOC:TermGenie] synonym: "regulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] is_a: GO:0043254 ! regulation of protein-containing complex assembly intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001677 ! formation of translation initiation ternary complex relationship: regulates GO:0001677 ! formation of translation initiation ternary complex created_by: ss creation_date: 2012-07-25T02:26:58Z [Term] id: GO:1901191 name: negative regulation of formation of translation initiation ternary complex namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of formation of translation initiation ternary complex." [GOC:TermGenie] synonym: "down regulation of formation of translation initiation ternary complex" EXACT [GOC:TermGenie] synonym: "down regulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of formation of translation initiation ternary complex" EXACT [GOC:TermGenie] synonym: "down-regulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] synonym: "downregulation of formation of translation initiation ternary complex" EXACT [GOC:TermGenie] synonym: "downregulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] synonym: "inhibition of formation of translation initiation ternary complex" NARROW [GOC:TermGenie] synonym: "inhibition of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] synonym: "negative regulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] is_a: GO:0031333 ! negative regulation of protein-containing complex assembly is_a: GO:0045947 ! negative regulation of translational initiation is_a: GO:1901190 ! regulation of formation of translation initiation ternary complex intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001677 ! formation of translation initiation ternary complex relationship: negatively_regulates GO:0001677 ! formation of translation initiation ternary complex created_by: ss creation_date: 2012-07-25T02:27:21Z [Term] id: GO:1901192 name: positive regulation of formation of translation initiation ternary complex namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of formation of translation initiation ternary complex." [GOC:TermGenie] synonym: "activation of formation of translation initiation ternary complex" NARROW [GOC:TermGenie] synonym: "activation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] synonym: "positive regulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] synonym: "up regulation of formation of translation initiation ternary complex" EXACT [GOC:TermGenie] synonym: "up regulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] synonym: "up-regulation of formation of translation initiation ternary complex" EXACT [GOC:TermGenie] synonym: "up-regulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] synonym: "upregulation of formation of translation initiation ternary complex" EXACT [GOC:TermGenie] synonym: "upregulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] is_a: GO:0031334 ! positive regulation of protein-containing complex assembly is_a: GO:1901190 ! regulation of formation of translation initiation ternary complex intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001677 ! formation of translation initiation ternary complex relationship: positively_regulates GO:0001677 ! formation of translation initiation ternary complex created_by: ss creation_date: 2012-07-25T02:27:29Z [Term] id: GO:1901201 name: regulation of extracellular matrix assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of extracellular matrix assembly." [GOC:BHF, GOC:TermGenie] is_a: GO:0044087 ! regulation of cellular component biogenesis is_a: GO:1903053 ! regulation of extracellular matrix organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0085029 ! extracellular matrix assembly relationship: regulates GO:0085029 ! extracellular matrix assembly created_by: rl creation_date: 2012-07-27T04:04:00Z [Term] id: GO:1901202 name: negative regulation of extracellular matrix assembly namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix assembly." [GOC:BHF, GOC:TermGenie] synonym: "down regulation of extracellular matrix assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of extracellular matrix assembly" EXACT [GOC:TermGenie] synonym: "downregulation of extracellular matrix assembly" EXACT [GOC:TermGenie] synonym: "inhibition of extracellular matrix assembly" NARROW [GOC:TermGenie] is_a: GO:1901201 ! regulation of extracellular matrix assembly is_a: GO:1903054 ! negative regulation of extracellular matrix organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0085029 ! extracellular matrix assembly relationship: negatively_regulates GO:0085029 ! extracellular matrix assembly created_by: rl creation_date: 2012-07-27T04:04:24Z [Term] id: GO:1901203 name: positive regulation of extracellular matrix assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of extracellular matrix assembly." [GOC:BHF, GOC:TermGenie] synonym: "activation of extracellular matrix assembly" NARROW [GOC:TermGenie] synonym: "up regulation of extracellular matrix assembly" EXACT [GOC:TermGenie] synonym: "up-regulation of extracellular matrix assembly" EXACT [GOC:TermGenie] synonym: "upregulation of extracellular matrix assembly" EXACT [GOC:TermGenie] is_a: GO:0044089 ! positive regulation of cellular component biogenesis is_a: GO:1901201 ! regulation of extracellular matrix assembly is_a: GO:1903055 ! positive regulation of extracellular matrix organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0085029 ! extracellular matrix assembly relationship: positively_regulates GO:0085029 ! extracellular matrix assembly created_by: rl creation_date: 2012-07-27T04:04:32Z [Term] id: GO:1901210 name: regulation of cardiac chamber formation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac chamber formation." [GOC:BHF, GOC:TermGenie] synonym: "regulation of heart chamber formation" EXACT [GOC:TermGenie] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003207 ! cardiac chamber formation relationship: regulates GO:0003207 ! cardiac chamber formation created_by: rl creation_date: 2012-07-31T07:18:35Z [Term] id: GO:1901211 name: negative regulation of cardiac chamber formation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber formation." [GOC:BHF, GOC:TermGenie] synonym: "down regulation of cardiac chamber formation" EXACT [GOC:TermGenie] synonym: "down regulation of heart chamber formation" EXACT [GOC:TermGenie] synonym: "down-regulation of cardiac chamber formation" EXACT [GOC:TermGenie] synonym: "down-regulation of heart chamber formation" EXACT [GOC:TermGenie] synonym: "downregulation of cardiac chamber formation" EXACT [GOC:TermGenie] synonym: "downregulation of heart chamber formation" EXACT [GOC:TermGenie] synonym: "inhibition of cardiac chamber formation" NARROW [GOC:TermGenie] synonym: "inhibition of heart chamber formation" EXACT [GOC:TermGenie] synonym: "negative regulation of heart chamber formation" EXACT [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:1901210 ! regulation of cardiac chamber formation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0003207 ! cardiac chamber formation relationship: negatively_regulates GO:0003207 ! cardiac chamber formation created_by: rl creation_date: 2012-07-31T07:18:57Z [Term] id: GO:1901212 name: positive regulation of cardiac chamber formation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cardiac chamber formation." [GOC:BHF, GOC:TermGenie] synonym: "activation of cardiac chamber formation" NARROW [GOC:TermGenie] synonym: "activation of heart chamber formation" EXACT [GOC:TermGenie] synonym: "positive regulation of heart chamber formation" EXACT [GOC:TermGenie] synonym: "up regulation of cardiac chamber formation" EXACT [GOC:TermGenie] synonym: "up regulation of heart chamber formation" EXACT [GOC:TermGenie] synonym: "up-regulation of cardiac chamber formation" EXACT [GOC:TermGenie] synonym: "up-regulation of heart chamber formation" EXACT [GOC:TermGenie] synonym: "upregulation of cardiac chamber formation" EXACT [GOC:TermGenie] synonym: "upregulation of heart chamber formation" EXACT [GOC:TermGenie] is_a: GO:1901210 ! regulation of cardiac chamber formation is_a: GO:1901221 ! positive regulation of cardiac chamber morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0003207 ! cardiac chamber formation relationship: positively_regulates GO:0003207 ! cardiac chamber formation created_by: rl creation_date: 2012-07-31T07:19:05Z [Term] id: GO:1901219 name: regulation of cardiac chamber morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac chamber morphogenesis." [GOC:BHF, GOC:TermGenie] synonym: "regulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] is_a: GO:2000826 ! regulation of heart morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003206 ! cardiac chamber morphogenesis relationship: regulates GO:0003206 ! cardiac chamber morphogenesis created_by: rl creation_date: 2012-08-06T17:59:11Z [Term] id: GO:1901220 name: negative regulation of cardiac chamber morphogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber morphogenesis." [GOC:BHF, GOC:TermGenie] synonym: "down regulation of cardiac chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "down regulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of cardiac chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of cardiac chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "inhibition of cardiac chamber morphogenesis" NARROW [GOC:TermGenie] synonym: "inhibition of heart chamber morphogenesis" NARROW [GOC:TermGenie] synonym: "negative regulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:1901219 ! regulation of cardiac chamber morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0003206 ! cardiac chamber morphogenesis relationship: negatively_regulates GO:0003206 ! cardiac chamber morphogenesis created_by: rl creation_date: 2012-08-06T17:59:34Z [Term] id: GO:1901221 name: positive regulation of cardiac chamber morphogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cardiac chamber morphogenesis." [GOC:BHF, GOC:TermGenie] synonym: "activation of cardiac chamber morphogenesis" NARROW [GOC:TermGenie] synonym: "activation of heart chamber morphogenesis" NARROW [GOC:TermGenie] synonym: "positive regulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of cardiac chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of cardiac chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of cardiac chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:1901219 ! regulation of cardiac chamber morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0003206 ! cardiac chamber morphogenesis relationship: positively_regulates GO:0003206 ! cardiac chamber morphogenesis created_by: rl creation_date: 2012-08-06T17:59:42Z [Term] id: GO:1901246 name: regulation of lung ciliated cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of lung ciliated cell differentiation." [GOC:BHF, GOC:TermGenie] is_a: GO:0030856 ! regulation of epithelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0061141 ! lung ciliated cell differentiation relationship: regulates GO:0061141 ! lung ciliated cell differentiation created_by: vk creation_date: 2012-08-08T08:58:34Z [Term] id: GO:1901247 name: negative regulation of lung ciliated cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of lung ciliated cell differentiation." [GOC:BHF, GOC:TermGenie] synonym: "down regulation of lung ciliated cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of lung ciliated cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of lung ciliated cell differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of lung ciliated cell differentiation" NARROW [GOC:TermGenie] is_a: GO:0030857 ! negative regulation of epithelial cell differentiation is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1901246 ! regulation of lung ciliated cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0061141 ! lung ciliated cell differentiation relationship: negatively_regulates GO:0061141 ! lung ciliated cell differentiation created_by: vk creation_date: 2012-08-08T08:58:58Z [Term] id: GO:1901248 name: positive regulation of lung ciliated cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of lung ciliated cell differentiation." [GOC:BHF, GOC:TermGenie] synonym: "activation of lung ciliated cell differentiation" NARROW [GOC:TermGenie] synonym: "up regulation of lung ciliated cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of lung ciliated cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of lung ciliated cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0030858 ! positive regulation of epithelial cell differentiation is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1901246 ! regulation of lung ciliated cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0061141 ! lung ciliated cell differentiation relationship: positively_regulates GO:0061141 ! lung ciliated cell differentiation created_by: vk creation_date: 2012-08-08T08:59:05Z [Term] id: GO:1901264 name: carbohydrate derivative transport namespace: biological_process def: "The directed movement of a carbohydrate derivative into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:bf, GOC:jl, GOC:TermGenie] is_a: GO:0071702 ! organic substance transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:63299 ! carbohydrate derivative relationship: has_primary_input CHEBI:63299 ! carbohydrate derivative created_by: bf creation_date: 2012-08-16T14:51:22Z [Term] id: GO:1901317 name: regulation of flagellated sperm motility namespace: biological_process def: "Any process that modulates the frequency, rate or extent of flagellated sperm motility." [GOC:cilia, GOC:krc, GOC:TermGenie] synonym: "regulation of sperm motility" BROAD [] synonym: "regulation of sperm movement" BROAD [GOC:TermGenie] is_a: GO:0060295 ! regulation of cilium movement involved in cell motility is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030317 ! flagellated sperm motility relationship: regulates GO:0030317 ! flagellated sperm motility created_by: hjd creation_date: 2012-08-22T20:50:14Z [Term] id: GO:1901318 name: negative regulation of flagellated sperm motility namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of flagellated sperm motility." [GOC:cilia, GOC:krc, GOC:TermGenie] synonym: "down regulation of sperm motility" BROAD [GOC:TermGenie] synonym: "down regulation of sperm movement" BROAD [GOC:TermGenie] synonym: "down-regulation of sperm motility" BROAD [GOC:TermGenie] synonym: "down-regulation of sperm movement" BROAD [GOC:TermGenie] synonym: "downregulation of sperm motility" BROAD [GOC:TermGenie] synonym: "downregulation of sperm movement" BROAD [GOC:TermGenie] synonym: "inhibition of sperm motility" NARROW [GOC:TermGenie] synonym: "inhibition of sperm movement" BROAD [GOC:TermGenie] synonym: "negative regulation of sperm motility" BROAD [] synonym: "negative regulation of sperm movement" BROAD [GOC:TermGenie] is_a: GO:0003354 ! negative regulation of cilium movement is_a: GO:1901317 ! regulation of flagellated sperm motility is_a: GO:1902020 ! negative regulation of cilium-dependent cell motility is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030317 ! flagellated sperm motility relationship: negatively_regulates GO:0030317 ! flagellated sperm motility created_by: hjd creation_date: 2012-08-22T20:50:35Z [Term] id: GO:1901342 name: regulation of vasculature development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of vasculature development." [GOC:TermGenie] synonym: "regulation of vascular system development" RELATED [GOC:TermGenie] is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001944 ! vasculature development relationship: regulates GO:0001944 ! vasculature development created_by: bf creation_date: 2012-09-06T09:16:15Z [Term] id: GO:1901343 name: negative regulation of vasculature development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of vasculature development." [GOC:TermGenie] synonym: "down regulation of vascular system development" RELATED [GOC:TermGenie] synonym: "down regulation of vasculature development" EXACT [GOC:TermGenie] synonym: "down-regulation of vascular system development" RELATED [GOC:TermGenie] synonym: "down-regulation of vasculature development" EXACT [GOC:TermGenie] synonym: "downregulation of vascular system development" RELATED [GOC:TermGenie] synonym: "downregulation of vasculature development" EXACT [GOC:TermGenie] synonym: "inhibition of vascular system development" RELATED [GOC:TermGenie] synonym: "inhibition of vasculature development" NARROW [GOC:TermGenie] synonym: "negative regulation of vascular system development" RELATED [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1901342 ! regulation of vasculature development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001944 ! vasculature development relationship: negatively_regulates GO:0001944 ! vasculature development created_by: bf creation_date: 2012-09-06T09:17:24Z [Term] id: GO:1901360 name: organic cyclic compound metabolic process namespace: biological_process def: "The chemical reactions and pathways involving organic cyclic compound." [GOC:TermGenie] synonym: "organic cyclic compound metabolism" EXACT [GOC:TermGenie] is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:33832 ! organic cyclic compound relationship: has_primary_input_or_output CHEBI:33832 ! organic cyclic compound created_by: bf creation_date: 2012-09-14T09:03:51Z [Term] id: GO:1901361 name: organic cyclic compound catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of organic cyclic compound." [GOC:TermGenie] synonym: "organic cyclic compound breakdown" EXACT [GOC:TermGenie] synonym: "organic cyclic compound catabolism" EXACT [GOC:TermGenie] synonym: "organic cyclic compound degradation" EXACT [GOC:TermGenie] is_a: GO:1901360 ! organic cyclic compound metabolic process is_a: GO:1901575 ! organic substance catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:33832 ! organic cyclic compound relationship: has_primary_input CHEBI:33832 ! organic cyclic compound created_by: bf creation_date: 2012-09-14T09:05:04Z [Term] id: GO:1901362 name: organic cyclic compound biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of organic cyclic compound." [GOC:TermGenie] synonym: "organic cyclic compound anabolism" EXACT [GOC:TermGenie] synonym: "organic cyclic compound biosynthesis" EXACT [GOC:TermGenie] synonym: "organic cyclic compound formation" EXACT [GOC:TermGenie] synonym: "organic cyclic compound synthesis" EXACT [GOC:TermGenie] is_a: GO:1901360 ! organic cyclic compound metabolic process is_a: GO:1901576 ! organic substance biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:33832 ! organic cyclic compound relationship: has_primary_output CHEBI:33832 ! organic cyclic compound created_by: bf creation_date: 2012-09-14T09:05:22Z [Term] id: GO:1901374 name: acetate ester transport namespace: biological_process def: "The directed movement of an acetate ester into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:TermGenie] is_a: GO:0071702 ! organic substance transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:47622 ! acetate ester relationship: has_primary_input CHEBI:47622 ! acetate ester created_by: bf creation_date: 2012-09-28T10:42:13Z [Term] id: GO:1901375 name: acetate ester transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of an acetate ester from one side of a membrane to the other." [GOC:TermGenie] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:47622 ! acetate ester relationship: has_primary_input CHEBI:47622 ! acetate ester relationship: part_of GO:1901374 ! acetate ester transport created_by: bf creation_date: 2012-09-28T10:47:08Z [Term] id: GO:1901382 name: regulation of chorionic trophoblast cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of chorionic trophoblast cell proliferation." [GOC:BHF, GOC:TermGenie] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0097360 ! chorionic trophoblast cell proliferation relationship: regulates GO:0097360 ! chorionic trophoblast cell proliferation created_by: vk creation_date: 2012-10-01T10:03:13Z [Term] id: GO:1901383 name: negative regulation of chorionic trophoblast cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of chorionic trophoblast cell proliferation." [GOC:BHF, GOC:TermGenie] synonym: "down regulation of chorionic trophoblast cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of chorionic trophoblast cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of chorionic trophoblast cell proliferation" EXACT [GOC:TermGenie] synonym: "inhibition of chorionic trophoblast cell proliferation" NARROW [GOC:TermGenie] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:1901382 ! regulation of chorionic trophoblast cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0097360 ! chorionic trophoblast cell proliferation relationship: negatively_regulates GO:0097360 ! chorionic trophoblast cell proliferation created_by: vk creation_date: 2012-10-01T10:04:23Z [Term] id: GO:1901384 name: positive regulation of chorionic trophoblast cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of chorionic trophoblast cell proliferation." [GOC:BHF, GOC:TermGenie] synonym: "activation of chorionic trophoblast cell proliferation" NARROW [GOC:TermGenie] synonym: "up regulation of chorionic trophoblast cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of chorionic trophoblast cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of chorionic trophoblast cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:1901382 ! regulation of chorionic trophoblast cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0097360 ! chorionic trophoblast cell proliferation relationship: positively_regulates GO:0097360 ! chorionic trophoblast cell proliferation created_by: vk creation_date: 2012-10-01T10:04:41Z [Term] id: GO:1901401 name: regulation of tetrapyrrole metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of tetrapyrrole metabolic process." [GOC:mengo_curators, GOC:TermGenie] synonym: "regulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] is_a: GO:0031323 ! regulation of cellular metabolic process is_a: GO:0051171 ! regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0033013 ! tetrapyrrole metabolic process relationship: regulates GO:0033013 ! tetrapyrrole metabolic process created_by: tt creation_date: 2012-10-01T14:34:03Z [Term] id: GO:1901402 name: negative regulation of tetrapyrrole metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole metabolic process." [GOC:mengo_curators, GOC:TermGenie] synonym: "down regulation of tetrapyrrole metabolic process" EXACT [GOC:TermGenie] synonym: "down regulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of tetrapyrrole metabolic process" EXACT [GOC:TermGenie] synonym: "down-regulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] synonym: "downregulation of tetrapyrrole metabolic process" EXACT [GOC:TermGenie] synonym: "downregulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] synonym: "inhibition of tetrapyrrole metabolic process" NARROW [GOC:TermGenie] synonym: "inhibition of tetrapyrrole metabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] is_a: GO:0031324 ! negative regulation of cellular metabolic process is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process is_a: GO:1901401 ! regulation of tetrapyrrole metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0033013 ! tetrapyrrole metabolic process relationship: negatively_regulates GO:0033013 ! tetrapyrrole metabolic process created_by: tt creation_date: 2012-10-01T14:35:11Z [Term] id: GO:1901403 name: positive regulation of tetrapyrrole metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of tetrapyrrole metabolic process." [GOC:mengo_curators, GOC:TermGenie] synonym: "activation of tetrapyrrole metabolic process" NARROW [GOC:TermGenie] synonym: "activation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] synonym: "up regulation of tetrapyrrole metabolic process" EXACT [GOC:TermGenie] synonym: "up regulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of tetrapyrrole metabolic process" EXACT [GOC:TermGenie] synonym: "up-regulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] synonym: "upregulation of tetrapyrrole metabolic process" EXACT [GOC:TermGenie] synonym: "upregulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] is_a: GO:0031325 ! positive regulation of cellular metabolic process is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process is_a: GO:1901401 ! regulation of tetrapyrrole metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0033013 ! tetrapyrrole metabolic process relationship: positively_regulates GO:0033013 ! tetrapyrrole metabolic process created_by: tt creation_date: 2012-10-01T14:35:29Z [Term] id: GO:1901404 name: regulation of tetrapyrrole catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of tetrapyrrole catabolic process." [GOC:mengo_curators, GOC:TermGenie] synonym: "regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] is_a: GO:0031329 ! regulation of cellular catabolic process is_a: GO:1901401 ! regulation of tetrapyrrole metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0033015 ! tetrapyrrole catabolic process relationship: regulates GO:0033015 ! tetrapyrrole catabolic process created_by: tt creation_date: 2012-10-01T14:38:12Z [Term] id: GO:1901405 name: negative regulation of tetrapyrrole catabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole catabolic process." [GOC:mengo_curators, GOC:TermGenie] synonym: "down regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "down regulation of tetrapyrrole catabolic process" EXACT [GOC:TermGenie] synonym: "down regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "down regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] synonym: "down-regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "down-regulation of tetrapyrrole catabolic process" EXACT [GOC:TermGenie] synonym: "down-regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] synonym: "downregulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "downregulation of tetrapyrrole catabolic process" EXACT [GOC:TermGenie] synonym: "downregulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "downregulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] synonym: "inhibition of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "inhibition of tetrapyrrole catabolic process" NARROW [GOC:TermGenie] synonym: "inhibition of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "inhibition of tetrapyrrole degradation" EXACT [GOC:TermGenie] synonym: "negative regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "negative regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] is_a: GO:0031330 ! negative regulation of cellular catabolic process is_a: GO:1901402 ! negative regulation of tetrapyrrole metabolic process is_a: GO:1901404 ! regulation of tetrapyrrole catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0033015 ! tetrapyrrole catabolic process relationship: negatively_regulates GO:0033015 ! tetrapyrrole catabolic process created_by: tt creation_date: 2012-10-01T14:39:22Z [Term] id: GO:1901406 name: positive regulation of tetrapyrrole catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of tetrapyrrole catabolic process." [GOC:mengo_curators, GOC:TermGenie] synonym: "activation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "activation of tetrapyrrole catabolic process" NARROW [GOC:TermGenie] synonym: "activation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "activation of tetrapyrrole degradation" EXACT [GOC:TermGenie] synonym: "positive regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "positive regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] synonym: "up regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "up regulation of tetrapyrrole catabolic process" EXACT [GOC:TermGenie] synonym: "up regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "up regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] synonym: "up-regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "up-regulation of tetrapyrrole catabolic process" EXACT [GOC:TermGenie] synonym: "up-regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] synonym: "upregulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "upregulation of tetrapyrrole catabolic process" EXACT [GOC:TermGenie] synonym: "upregulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "upregulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] is_a: GO:0031331 ! positive regulation of cellular catabolic process is_a: GO:1901403 ! positive regulation of tetrapyrrole metabolic process is_a: GO:1901404 ! regulation of tetrapyrrole catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0033015 ! tetrapyrrole catabolic process relationship: positively_regulates GO:0033015 ! tetrapyrrole catabolic process created_by: tt creation_date: 2012-10-01T14:39:40Z [Term] id: GO:1901457 name: regulation of response to acetate namespace: biological_process def: "Any process that modulates the frequency, rate or extent of response to acetate." [GOC:mengo_curators, GOC:TermGenie] is_a: GO:0048583 ! regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0010034 ! response to acetate relationship: regulates GO:0010034 ! response to acetate created_by: tt creation_date: 2012-10-02T14:25:06Z [Term] id: GO:1901458 name: negative regulation of response to acetate namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of response to acetate." [GOC:mengo_curators, GOC:TermGenie] synonym: "down regulation of response to acetate" EXACT [GOC:TermGenie] synonym: "down-regulation of response to acetate" EXACT [GOC:TermGenie] synonym: "downregulation of response to acetate" EXACT [GOC:TermGenie] synonym: "inhibition of response to acetate" NARROW [GOC:TermGenie] is_a: GO:0048585 ! negative regulation of response to stimulus is_a: GO:1901457 ! regulation of response to acetate intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0010034 ! response to acetate relationship: negatively_regulates GO:0010034 ! response to acetate created_by: tt creation_date: 2012-10-02T14:26:15Z [Term] id: GO:1901459 name: positive regulation of response to acetate namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of response to acetate." [GOC:mengo_curators, GOC:TermGenie] synonym: "activation of response to acetate" NARROW [GOC:TermGenie] synonym: "up regulation of response to acetate" EXACT [GOC:TermGenie] synonym: "up-regulation of response to acetate" EXACT [GOC:TermGenie] synonym: "upregulation of response to acetate" EXACT [GOC:TermGenie] is_a: GO:0048584 ! positive regulation of response to stimulus is_a: GO:1901457 ! regulation of response to acetate intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0010034 ! response to acetate relationship: positively_regulates GO:0010034 ! response to acetate created_by: tt creation_date: 2012-10-02T14:26:34Z [Term] id: GO:1901463 name: regulation of tetrapyrrole biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of tetrapyrrole biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] synonym: "regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "regulation of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] is_a: GO:0031326 ! regulation of cellular biosynthetic process is_a: GO:1901401 ! regulation of tetrapyrrole metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0033014 ! tetrapyrrole biosynthetic process relationship: regulates GO:0033014 ! tetrapyrrole biosynthetic process created_by: tt creation_date: 2012-10-02T14:34:14Z [Term] id: GO:1901464 name: negative regulation of tetrapyrrole biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] synonym: "down regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "down regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "down regulation of tetrapyrrole biosynthetic process" EXACT [GOC:TermGenie] synonym: "down regulation of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "down regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of tetrapyrrole biosynthetic process" EXACT [GOC:TermGenie] synonym: "down-regulation of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "down-regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] synonym: "downregulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "downregulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "downregulation of tetrapyrrole biosynthetic process" EXACT [GOC:TermGenie] synonym: "downregulation of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "downregulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] synonym: "inhibition of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "inhibition of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "inhibition of tetrapyrrole biosynthetic process" NARROW [GOC:TermGenie] synonym: "inhibition of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "inhibition of tetrapyrrole synthesis" EXACT [GOC:TermGenie] synonym: "negative regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "negative regulation of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "negative regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] is_a: GO:0031327 ! negative regulation of cellular biosynthetic process is_a: GO:1901402 ! negative regulation of tetrapyrrole metabolic process is_a: GO:1901463 ! regulation of tetrapyrrole biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0033014 ! tetrapyrrole biosynthetic process relationship: negatively_regulates GO:0033014 ! tetrapyrrole biosynthetic process created_by: tt creation_date: 2012-10-02T14:35:26Z [Term] id: GO:1901465 name: positive regulation of tetrapyrrole biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] synonym: "activation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "activation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "activation of tetrapyrrole biosynthetic process" NARROW [GOC:TermGenie] synonym: "activation of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "activation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] synonym: "positive regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "positive regulation of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "positive regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] synonym: "up regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "up regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "up regulation of tetrapyrrole biosynthetic process" EXACT [GOC:TermGenie] synonym: "up regulation of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "up regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of tetrapyrrole biosynthetic process" EXACT [GOC:TermGenie] synonym: "up-regulation of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "up-regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] synonym: "upregulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "upregulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "upregulation of tetrapyrrole biosynthetic process" EXACT [GOC:TermGenie] synonym: "upregulation of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "upregulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] is_a: GO:0031328 ! positive regulation of cellular biosynthetic process is_a: GO:1901403 ! positive regulation of tetrapyrrole metabolic process is_a: GO:1901463 ! regulation of tetrapyrrole biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0033014 ! tetrapyrrole biosynthetic process relationship: positively_regulates GO:0033014 ! tetrapyrrole biosynthetic process created_by: tt creation_date: 2012-10-02T14:35:43Z [Term] id: GO:1901505 name: carbohydrate derivative transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of carbohydrate derivative from one side of a membrane to the other." [GOC:pr, GOC:TermGenie] synonym: "carbohydrate derivative transporter activity" RELATED [] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:63299 ! carbohydrate derivative relationship: has_primary_input CHEBI:63299 ! carbohydrate derivative relationship: part_of GO:1901264 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! carbohydrate derivative transport created_by: pr creation_date: 2012-10-17T10:31:22Z [Term] id: GO:1901509 name: regulation of endothelial tube morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of endothelial tube morphogenesis." [GOC:dph, GOC:TermGenie] is_a: GO:1905330 ! regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0061154 ! endothelial tube morphogenesis relationship: regulates GO:0061154 ! endothelial tube morphogenesis created_by: dph creation_date: 2012-10-17T14:30:40Z [Term] id: GO:1901532 name: regulation of hematopoietic progenitor cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of hematopoietic progenitor cell differentiation." [GOC:BHF, GOC:rl, GOC:TermGenie] synonym: "regulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "regulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "regulation of hemopoietic progenitor cell differentiation" EXACT [] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002244 ! hematopoietic progenitor cell differentiation relationship: regulates GO:0002244 ! hematopoietic progenitor cell differentiation created_by: vk creation_date: 2012-10-24T11:23:01Z [Term] id: GO:1901533 name: negative regulation of hematopoietic progenitor cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic progenitor cell differentiation." [GOC:BHF, GOC:rl, GOC:TermGenie] synonym: "down regulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of hematopoietic progenitor cell differentiation" RELATED [GOC:TermGenie] synonym: "down regulation of hemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of hematopoietic progenitor cell differentiation" RELATED [GOC:TermGenie] synonym: "down-regulation of hemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of hematopoietic progenitor cell differentiation" RELATED [GOC:TermGenie] synonym: "downregulation of hemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of hematopoietic progenitor cell differentiation" RELATED [GOC:TermGenie] synonym: "inhibition of hemopoietic progenitor cell differentiation" NARROW [GOC:TermGenie] synonym: "negative regulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "negative regulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "negative regulation of hemopoietic progenitor cell differentiation" EXACT [] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:1901532 ! regulation of hematopoietic progenitor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002244 ! hematopoietic progenitor cell differentiation relationship: negatively_regulates GO:0002244 ! hematopoietic progenitor cell differentiation created_by: vk creation_date: 2012-10-24T11:23:06Z [Term] id: GO:1901534 name: positive regulation of hematopoietic progenitor cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of hematopoietic progenitor cell differentiation." [GOC:BHF, GOC:rl, GOC:TermGenie] synonym: "activation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "activation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "activation of hematopoietic progenitor cell differentiation" RELATED [GOC:TermGenie] synonym: "activation of hemopoietic progenitor cell differentiation" NARROW [GOC:TermGenie] synonym: "positive regulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "positive regulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "positive regulation of hemopoietic progenitor cell differentiation" EXACT [] synonym: "up regulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of hematopoietic progenitor cell differentiation" RELATED [GOC:TermGenie] synonym: "up regulation of hemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of hematopoietic progenitor cell differentiation" RELATED [GOC:TermGenie] synonym: "up-regulation of hemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of hematopoietic progenitor cell differentiation" RELATED [GOC:TermGenie] synonym: "upregulation of hemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:1901532 ! regulation of hematopoietic progenitor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002244 ! hematopoietic progenitor cell differentiation relationship: positively_regulates GO:0002244 ! hematopoietic progenitor cell differentiation created_by: vk creation_date: 2012-10-24T11:23:14Z [Term] id: GO:1901550 name: regulation of endothelial cell development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of endothelial cell development." [GOC:pr, GOC:TermGenie, PMID:19470579] is_a: GO:0045601 ! regulation of endothelial cell differentiation is_a: GO:0060284 ! regulation of cell development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001885 ! endothelial cell development relationship: regulates GO:0001885 ! endothelial cell development created_by: pr creation_date: 2012-10-30T12:59:50Z [Term] id: GO:1901551 name: negative regulation of endothelial cell development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell development." [GOC:pr, GOC:TermGenie, PMID:19470579] synonym: "down regulation of endothelial cell development" EXACT [GOC:TermGenie] synonym: "down-regulation of endothelial cell development" EXACT [GOC:TermGenie] synonym: "downregulation of endothelial cell development" EXACT [GOC:TermGenie] synonym: "inhibition of endothelial cell development" NARROW [GOC:TermGenie] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0045602 ! negative regulation of endothelial cell differentiation is_a: GO:1901550 ! regulation of endothelial cell development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001885 ! endothelial cell development relationship: negatively_regulates GO:0001885 ! endothelial cell development created_by: pr creation_date: 2012-10-30T12:59:54Z [Term] id: GO:1901552 name: positive regulation of endothelial cell development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of endothelial cell development." [GOC:pr, GOC:TermGenie, PMID:19470579] synonym: "activation of endothelial cell development" NARROW [GOC:TermGenie] synonym: "up regulation of endothelial cell development" EXACT [GOC:TermGenie] synonym: "up-regulation of endothelial cell development" EXACT [GOC:TermGenie] synonym: "upregulation of endothelial cell development" EXACT [GOC:TermGenie] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:1901550 ! regulation of endothelial cell development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001885 ! endothelial cell development relationship: positively_regulates GO:0001885 ! endothelial cell development created_by: pr creation_date: 2012-10-30T12:59:58Z [Term] id: GO:1901564 name: organonitrogen compound metabolic process namespace: biological_process def: "The chemical reactions and pathways involving organonitrogen compound." [GOC:pr, GOC:TermGenie] subset: gocheck_do_not_annotate synonym: "organonitrogen compound metabolism" EXACT [GOC:TermGenie] is_a: GO:0006807 ! nitrogen compound metabolic process is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:35352 ! organonitrogen compound relationship: has_primary_input_or_output CHEBI:35352 ! organonitrogen compound property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI created_by: pr creation_date: 2012-11-04T15:17:52Z [Term] id: GO:1901565 name: organonitrogen compound catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of organonitrogen compound." [GOC:pr, GOC:TermGenie] synonym: "organonitrogen compound breakdown" EXACT [GOC:TermGenie] synonym: "organonitrogen compound catabolism" EXACT [GOC:TermGenie] synonym: "organonitrogen compound degradation" EXACT [GOC:TermGenie] is_a: GO:1901564 ! organonitrogen compound metabolic process is_a: GO:1901575 ! organic substance catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:35352 ! organonitrogen compound relationship: has_primary_input CHEBI:35352 ! organonitrogen compound created_by: pr creation_date: 2012-11-04T15:17:56Z [Term] id: GO:1901566 name: organonitrogen compound biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of organonitrogen compound." [GOC:pr, GOC:TermGenie] synonym: "organonitrogen compound anabolism" EXACT [GOC:TermGenie] synonym: "organonitrogen compound biosynthesis" EXACT [GOC:TermGenie] synonym: "organonitrogen compound formation" EXACT [GOC:TermGenie] synonym: "organonitrogen compound synthesis" EXACT [GOC:TermGenie] is_a: GO:1901564 ! organonitrogen compound metabolic process is_a: GO:1901576 ! organic substance biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:35352 ! organonitrogen compound relationship: has_primary_output CHEBI:35352 ! organonitrogen compound created_by: pr creation_date: 2012-11-04T15:18:00Z [Term] id: GO:1901575 name: organic substance catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of an organic substance, any molecular entity containing carbon." [GOC:pr, GOC:TermGenie] synonym: "organic molecular entity breakdown" EXACT [GOC:TermGenie] synonym: "organic molecular entity catabolic process" EXACT [] synonym: "organic molecular entity catabolism" EXACT [GOC:TermGenie] synonym: "organic molecular entity degradation" EXACT [GOC:TermGenie] synonym: "organic substance breakdown" EXACT [] synonym: "organic substance catabolism" EXACT [] synonym: "organic substance degradation" EXACT [] is_a: GO:0009056 ! catabolic process is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:50860 ! organic molecular entity relationship: has_primary_input CHEBI:50860 ! organic molecular entity created_by: pr creation_date: 2012-11-05T11:04:36Z [Term] id: GO:1901576 name: organic substance biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of an organic substance, any molecular entity containing carbon." [GOC:pr, GOC:TermGenie] synonym: "organic molecular entity anabolism" EXACT [GOC:TermGenie] synonym: "organic molecular entity biosynthesis" EXACT [GOC:TermGenie] synonym: "organic molecular entity biosynthetic process" EXACT [] synonym: "organic molecular entity formation" EXACT [GOC:TermGenie] synonym: "organic molecular entity synthesis" EXACT [GOC:TermGenie] synonym: "organic substance anabolism" EXACT [] synonym: "organic substance biosynthesis" EXACT [] synonym: "organic substance formation" EXACT [] synonym: "organic substance synthesis" EXACT [] is_a: GO:0009058 ! biosynthetic process is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:50860 ! organic molecular entity relationship: has_primary_output CHEBI:50860 ! organic molecular entity created_by: pr creation_date: 2012-11-05T11:04:40Z [Term] id: GO:1901605 name: alpha-amino acid metabolic process namespace: biological_process def: "The chemical reactions and pathways involving an alpha-amino acid." [GOC:TermGenie] synonym: "alpha-amino acid metabolism" EXACT [GOC:TermGenie] is_a: GO:0006520 ! amino acid metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:78608 ! alpha-amino acid zwitterion relationship: has_primary_input_or_output CHEBI:78608 ! alpha-amino acid zwitterion created_by: tb creation_date: 2012-11-08T17:39:50Z [Term] id: GO:1901606 name: alpha-amino acid catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of an alpha-amino acid." [GOC:TermGenie] synonym: "alpha-amino acid breakdown" EXACT [GOC:TermGenie] synonym: "alpha-amino acid catabolism" EXACT [GOC:TermGenie] synonym: "alpha-amino acid degradation" EXACT [GOC:TermGenie] is_a: GO:1901575 ! organic substance catabolic process is_a: GO:1901605 ! alpha-amino acid metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:78608 ! alpha-amino acid zwitterion relationship: has_primary_input CHEBI:78608 ! alpha-amino acid zwitterion created_by: tb creation_date: 2012-11-08T17:39:54Z [Term] id: GO:1901607 name: alpha-amino acid biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of an alpha-amino acid." [GOC:TermGenie] synonym: "alpha-amino acid anabolism" EXACT [GOC:TermGenie] synonym: "alpha-amino acid biosynthesis" EXACT [GOC:TermGenie] synonym: "alpha-amino acid formation" EXACT [GOC:TermGenie] synonym: "alpha-amino acid synthesis" EXACT [GOC:TermGenie] is_a: GO:1901576 ! organic substance biosynthetic process is_a: GO:1901605 ! alpha-amino acid metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:78608 ! alpha-amino acid zwitterion relationship: has_primary_output CHEBI:78608 ! alpha-amino acid zwitterion created_by: tb creation_date: 2012-11-08T17:39:58Z [Term] id: GO:1901608 name: regulation of vesicle transport along microtubule namespace: biological_process def: "Any process that modulates the frequency, rate or extent of vesicle transport along microtubule." [GOC:TermGenie] synonym: "regulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] is_a: GO:1902513 ! regulation of organelle transport along microtubule intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0047496 ! vesicle transport along microtubule relationship: regulates GO:0047496 ! vesicle transport along microtubule created_by: hjd creation_date: 2012-11-08T21:49:44Z [Term] id: GO:1901609 name: negative regulation of vesicle transport along microtubule namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of vesicle transport along microtubule." [GOC:TermGenie] synonym: "down regulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] synonym: "down regulation of vesicle transport along microtubule" EXACT [GOC:TermGenie] synonym: "down-regulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] synonym: "down-regulation of vesicle transport along microtubule" EXACT [GOC:TermGenie] synonym: "downregulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] synonym: "downregulation of vesicle transport along microtubule" EXACT [GOC:TermGenie] synonym: "inhibition of microtubule-based vesicle localization" EXACT [GOC:TermGenie] synonym: "inhibition of vesicle transport along microtubule" NARROW [GOC:TermGenie] synonym: "negative regulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] is_a: GO:0032387 ! negative regulation of intracellular transport is_a: GO:1901608 ! regulation of vesicle transport along microtubule intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0047496 ! vesicle transport along microtubule relationship: negatively_regulates GO:0047496 ! vesicle transport along microtubule created_by: hjd creation_date: 2012-11-08T21:49:48Z [Term] id: GO:1901610 name: positive regulation of vesicle transport along microtubule namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of vesicle transport along microtubule." [GOC:TermGenie] synonym: "activation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] synonym: "activation of vesicle transport along microtubule" NARROW [GOC:TermGenie] synonym: "positive regulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] synonym: "up regulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] synonym: "up regulation of vesicle transport along microtubule" EXACT [GOC:TermGenie] synonym: "up-regulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] synonym: "up-regulation of vesicle transport along microtubule" EXACT [GOC:TermGenie] synonym: "upregulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] synonym: "upregulation of vesicle transport along microtubule" EXACT [GOC:TermGenie] is_a: GO:0032388 ! positive regulation of intracellular transport is_a: GO:1901608 ! regulation of vesicle transport along microtubule intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0047496 ! vesicle transport along microtubule relationship: positively_regulates GO:0047496 ! vesicle transport along microtubule created_by: hjd creation_date: 2012-11-08T21:49:53Z [Term] id: GO:1901615 name: organic hydroxy compound metabolic process namespace: biological_process def: "The chemical reactions and pathways involving organic hydroxy compound." [GOC:pr, GOC:TermGenie] synonym: "organic hydroxy compound metabolism" EXACT [GOC:TermGenie] is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:33822 ! organic hydroxy compound relationship: has_primary_input_or_output CHEBI:33822 ! organic hydroxy compound created_by: pr creation_date: 2012-11-13T12:54:27Z [Term] id: GO:1901616 name: organic hydroxy compound catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of organic hydroxy compound." [GOC:pr, GOC:TermGenie] synonym: "organic hydroxy compound breakdown" EXACT [GOC:TermGenie] synonym: "organic hydroxy compound catabolism" EXACT [GOC:TermGenie] synonym: "organic hydroxy compound degradation" EXACT [GOC:TermGenie] is_a: GO:1901575 ! organic substance catabolic process is_a: GO:1901615 ! organic hydroxy compound metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:33822 ! organic hydroxy compound relationship: has_primary_input CHEBI:33822 ! organic hydroxy compound created_by: pr creation_date: 2012-11-13T12:54:31Z [Term] id: GO:1901617 name: organic hydroxy compound biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of organic hydroxy compound." [GOC:pr, GOC:TermGenie] synonym: "organic hydroxy compound anabolism" EXACT [GOC:TermGenie] synonym: "organic hydroxy compound biosynthesis" EXACT [GOC:TermGenie] synonym: "organic hydroxy compound formation" EXACT [GOC:TermGenie] synonym: "organic hydroxy compound synthesis" EXACT [GOC:TermGenie] is_a: GO:1901576 ! organic substance biosynthetic process is_a: GO:1901615 ! organic hydroxy compound metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:33822 ! organic hydroxy compound relationship: has_primary_output CHEBI:33822 ! organic hydroxy compound created_by: pr creation_date: 2012-11-13T12:54:36Z [Term] id: GO:1901618 name: organic hydroxy compound transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of organic hydroxy compound from one side of a membrane to the other." [GOC:pr, GOC:TermGenie] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:33822 ! organic hydroxy compound relationship: has_primary_input CHEBI:33822 ! organic hydroxy compound created_by: pr creation_date: 2012-11-13T12:59:01Z [Term] id: GO:1901652 name: response to peptide namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus." [GOC:pr, GOC:TermGenie] is_a: GO:0010243 ! response to organonitrogen compound is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus intersection_of: has_primary_input CHEBI:16670 ! peptide relationship: has_primary_input CHEBI:16670 ! peptide created_by: pr creation_date: 2012-11-20T09:45:15Z [Term] id: GO:1901654 name: response to ketone namespace: biological_process alt_id: GO:1990369 def: "A response that results in a state of tolerance to ketone." [GOC:mengo_curators, PMID:23356676] synonym: "process resulting in tolerance to ketone" NARROW [] is_a: GO:0010033 ! response to organic substance is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus intersection_of: has_primary_input CHEBI:17087 ! ketone relationship: has_primary_input CHEBI:17087 ! ketone created_by: pr creation_date: 2012-11-20T10:55:47Z [Term] id: GO:1901682 name: sulfur compound transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of a sulfur compound from one side of a membrane to the other." [GOC:pr, GOC:TermGenie] synonym: "sulfur molecular entity transmembrane transporter activity" EXACT [] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:26835 ! sulfur molecular entity relationship: has_primary_input CHEBI:26835 ! sulfur molecular entity created_by: pr creation_date: 2012-11-26T20:45:29Z [Term] id: GO:1901692 name: regulation of compound eye retinal cell apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of compound eye retinal cell apoptotic process." [GOC:mtg_apoptosis, GOC:TermGenie, PMID:12021768] is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1990010 ! compound eye retinal cell apoptotic process relationship: regulates GO:1990010 ! compound eye retinal cell apoptotic process created_by: pr creation_date: 2012-12-12T10:28:35Z [Term] id: GO:1901693 name: negative regulation of compound eye retinal cell apoptotic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of compound eye retinal cell apoptotic process." [GOC:mtg_apoptosis, GOC:TermGenie, PMID:12021768] synonym: "down regulation of compound eye retinal cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of compound eye retinal cell apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of compound eye retinal cell apoptotic process" EXACT [GOC:TermGenie] synonym: "inhibition of compound eye retinal cell apoptotic process" NARROW [GOC:TermGenie] is_a: GO:0043066 ! negative regulation of apoptotic process is_a: GO:1901692 ! regulation of compound eye retinal cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1990010 ! compound eye retinal cell apoptotic process relationship: negatively_regulates GO:1990010 ! compound eye retinal cell apoptotic process created_by: pr creation_date: 2012-12-12T10:28:40Z [Term] id: GO:1901694 name: positive regulation of compound eye retinal cell apoptotic process namespace: biological_process alt_id: GO:0046675 def: "Any process that activates or increases the frequency, rate or extent of compound eye retinal cell apoptotic process." [GOC:mtg_apoptosis, GOC:TermGenie, PMID:12021768] synonym: "activation of compound eye retinal cell apoptotic process" NARROW [GOC:TermGenie] synonym: "induction of compound eye retinal cell programmed cell death" RELATED [] synonym: "up regulation of compound eye retinal cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of compound eye retinal cell apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of compound eye retinal cell apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0043065 ! positive regulation of apoptotic process is_a: GO:0046672 ! positive regulation of compound eye retinal cell programmed cell death is_a: GO:1901692 ! regulation of compound eye retinal cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1990010 ! compound eye retinal cell apoptotic process relationship: positively_regulates GO:1990010 ! compound eye retinal cell apoptotic process created_by: pr creation_date: 2012-12-12T10:28:45Z [Term] id: GO:1901698 name: response to nitrogen compound namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus." [GOC:pr, GOC:TermGenie] synonym: "response to nitrogen molecular entity" EXACT [] is_a: GO:0042221 ! response to chemical intersection_of: GO:0050896 ! response to stimulus intersection_of: has_primary_input CHEBI:51143 ! nitrogen molecular entity relationship: has_primary_input CHEBI:51143 ! nitrogen molecular entity created_by: pr creation_date: 2012-12-13T15:06:08Z [Term] id: GO:1901700 name: response to oxygen-containing compound namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus." [GOC:pr, GOC:TermGenie] synonym: "response to oxygen molecular entity" EXACT [] is_a: GO:0042221 ! response to chemical intersection_of: GO:0050896 ! response to stimulus intersection_of: has_primary_input CHEBI:25806 ! oxygen molecular entity relationship: has_primary_input CHEBI:25806 ! oxygen molecular entity created_by: pr creation_date: 2012-12-13T15:11:37Z [Term] id: GO:1901702 name: salt transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of salt from one side of a membrane to the other." [GOC:pr, GOC:TermGenie] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:24866 ! salt relationship: has_primary_input CHEBI:24866 ! salt created_by: pr creation_date: 2012-12-13T15:14:47Z [Term] id: GO:1901706 name: mesenchymal cell differentiation involved in bone development namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of bone as it progresses from its formation to the mature state." [GOC:hjd, GOC:TermGenie, PMID:21571217] is_a: GO:0048762 ! mesenchymal cell differentiation intersection_of: GO:0048762 ! mesenchymal cell differentiation intersection_of: part_of GO:0060348 ! bone development relationship: part_of GO:0060348 ! bone development created_by: hjd creation_date: 2012-12-14T16:04:16Z [Term] id: GO:1901722 name: regulation of cell proliferation involved in kidney development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell proliferation involved in kidney development." [GOC:TermGenie, PMID:18182616] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0072111 ! cell proliferation involved in kidney development relationship: regulates GO:0072111 ! cell proliferation involved in kidney development created_by: krc creation_date: 2012-12-27T19:30:31Z [Term] id: GO:1901723 name: negative regulation of cell proliferation involved in kidney development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in kidney development." [GOC:TermGenie, PMID:18182616] synonym: "down regulation of cell proliferation involved in kidney development" EXACT [GOC:TermGenie] synonym: "down-regulation of cell proliferation involved in kidney development" EXACT [GOC:TermGenie] synonym: "downregulation of cell proliferation involved in kidney development" EXACT [GOC:TermGenie] synonym: "inhibition of cell proliferation involved in kidney development" NARROW [GOC:TermGenie] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:1901722 ! regulation of cell proliferation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0072111 ! cell proliferation involved in kidney development relationship: negatively_regulates GO:0072111 ! cell proliferation involved in kidney development created_by: krc creation_date: 2012-12-27T19:30:35Z [Term] id: GO:1901724 name: positive regulation of cell proliferation involved in kidney development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell proliferation involved in kidney development." [GOC:TermGenie, PMID:18182616] synonym: "activation of cell proliferation involved in kidney development" NARROW [GOC:TermGenie] synonym: "up regulation of cell proliferation involved in kidney development" EXACT [GOC:TermGenie] synonym: "up-regulation of cell proliferation involved in kidney development" EXACT [GOC:TermGenie] synonym: "upregulation of cell proliferation involved in kidney development" EXACT [GOC:TermGenie] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:1901722 ! regulation of cell proliferation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0072111 ! cell proliferation involved in kidney development relationship: positively_regulates GO:0072111 ! cell proliferation involved in kidney development created_by: krc creation_date: 2012-12-27T19:30:40Z [Term] id: GO:1901861 name: regulation of muscle tissue development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of muscle tissue development." [GOC:TermGenie, GOC:yaf, PMID:23150719] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060537 ! muscle tissue development relationship: regulates GO:0060537 ! muscle tissue development created_by: yaf creation_date: 2013-02-01T10:30:47Z [Term] id: GO:1901862 name: negative regulation of muscle tissue development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of muscle tissue development." [GOC:TermGenie, GOC:yaf, PMID:23150719] synonym: "down regulation of muscle tissue development" EXACT [GOC:TermGenie] synonym: "down-regulation of muscle tissue development" EXACT [GOC:TermGenie] synonym: "downregulation of muscle tissue development" EXACT [GOC:TermGenie] synonym: "inhibition of muscle tissue development" NARROW [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:1901861 ! regulation of muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060537 ! muscle tissue development relationship: negatively_regulates GO:0060537 ! muscle tissue development created_by: yaf creation_date: 2013-02-01T10:30:52Z [Term] id: GO:1901863 name: positive regulation of muscle tissue development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of muscle tissue development." [GOC:TermGenie, GOC:yaf, PMID:23150719] synonym: "activation of muscle tissue development" NARROW [GOC:TermGenie] synonym: "up regulation of muscle tissue development" EXACT [GOC:TermGenie] synonym: "up-regulation of muscle tissue development" EXACT [GOC:TermGenie] synonym: "upregulation of muscle tissue development" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:1901861 ! regulation of muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060537 ! muscle tissue development relationship: positively_regulates GO:0060537 ! muscle tissue development created_by: yaf creation_date: 2013-02-01T10:30:57Z [Term] id: GO:1901879 name: regulation of protein depolymerization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein depolymerization." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:12032137] synonym: "regulation of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "regulation of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "regulation of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "regulation of protein polymer degradation" EXACT [GOC:TermGenie] is_a: GO:0043244 ! regulation of protein-containing complex disassembly intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0051261 ! protein depolymerization relationship: regulates GO:0051261 ! protein depolymerization created_by: rl creation_date: 2013-02-06T13:57:23Z [Term] id: GO:1901880 name: negative regulation of protein depolymerization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein depolymerization." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:12032137] synonym: "down regulation of protein depolymerization" EXACT [GOC:TermGenie] synonym: "down regulation of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "down regulation of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "down regulation of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "down regulation of protein polymer degradation" EXACT [GOC:TermGenie] synonym: "down-regulation of protein depolymerization" EXACT [GOC:TermGenie] synonym: "down-regulation of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "down-regulation of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "down-regulation of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of protein polymer degradation" EXACT [GOC:TermGenie] synonym: "downregulation of protein depolymerization" EXACT [GOC:TermGenie] synonym: "downregulation of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "downregulation of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "downregulation of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "downregulation of protein polymer degradation" EXACT [GOC:TermGenie] synonym: "inhibition of protein depolymerization" NARROW [GOC:TermGenie] synonym: "inhibition of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "inhibition of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "inhibition of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "inhibition of protein polymer degradation" EXACT [GOC:TermGenie] synonym: "negative regulation of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "negative regulation of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "negative regulation of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of protein polymer degradation" EXACT [GOC:TermGenie] is_a: GO:0043242 ! negative regulation of protein-containing complex disassembly is_a: GO:1901879 ! regulation of protein depolymerization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0051261 ! protein depolymerization relationship: negatively_regulates GO:0051261 ! protein depolymerization created_by: rl creation_date: 2013-02-06T13:57:28Z [Term] id: GO:1901881 name: positive regulation of protein depolymerization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein depolymerization." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:12032137] synonym: "activation of protein depolymerization" NARROW [GOC:TermGenie] synonym: "activation of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "activation of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "activation of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "activation of protein polymer degradation" EXACT [GOC:TermGenie] synonym: "positive regulation of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "positive regulation of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "positive regulation of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of protein polymer degradation" EXACT [GOC:TermGenie] synonym: "up regulation of protein depolymerization" EXACT [GOC:TermGenie] synonym: "up regulation of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "up regulation of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "up regulation of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "up regulation of protein polymer degradation" EXACT [GOC:TermGenie] synonym: "up-regulation of protein depolymerization" EXACT [GOC:TermGenie] synonym: "up-regulation of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "up-regulation of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "up-regulation of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of protein polymer degradation" EXACT [GOC:TermGenie] synonym: "upregulation of protein depolymerization" EXACT [GOC:TermGenie] synonym: "upregulation of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "upregulation of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "upregulation of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "upregulation of protein polymer degradation" EXACT [GOC:TermGenie] is_a: GO:0043243 ! positive regulation of protein-containing complex disassembly is_a: GO:1901879 ! regulation of protein depolymerization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0051261 ! protein depolymerization relationship: positively_regulates GO:0051261 ! protein depolymerization created_by: rl creation_date: 2013-02-06T13:57:32Z [Term] id: GO:1901888 name: regulation of cell junction assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell junction assembly." [GOC:TermGenie] is_a: GO:0044087 ! regulation of cellular component biogenesis is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0034329 ! cell junction assembly relationship: regulates GO:0034329 ! cell junction assembly created_by: tb creation_date: 2013-02-06T19:40:32Z [Term] id: GO:1901889 name: negative regulation of cell junction assembly namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell junction assembly." [GOC:TermGenie] synonym: "down regulation of cell junction assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of cell junction assembly" EXACT [GOC:TermGenie] synonym: "downregulation of cell junction assembly" EXACT [GOC:TermGenie] synonym: "inhibition of cell junction assembly" NARROW [GOC:TermGenie] is_a: GO:0051129 ! negative regulation of cellular component organization is_a: GO:1901888 ! regulation of cell junction assembly intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0034329 ! cell junction assembly relationship: negatively_regulates GO:0034329 ! cell junction assembly created_by: tb creation_date: 2013-02-06T19:40:41Z [Term] id: GO:1901890 name: positive regulation of cell junction assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell junction assembly." [GOC:TermGenie] synonym: "activation of cell junction assembly" NARROW [GOC:TermGenie] synonym: "up regulation of cell junction assembly" EXACT [GOC:TermGenie] synonym: "up-regulation of cell junction assembly" EXACT [GOC:TermGenie] synonym: "upregulation of cell junction assembly" EXACT [GOC:TermGenie] is_a: GO:0044089 ! positive regulation of cellular component biogenesis is_a: GO:0051130 ! positive regulation of cellular component organization is_a: GO:1901888 ! regulation of cell junction assembly intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0034329 ! cell junction assembly relationship: positively_regulates GO:0034329 ! cell junction assembly created_by: tb creation_date: 2013-02-06T19:40:46Z [Term] id: GO:1901963 name: regulation of cell proliferation involved in outflow tract morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis." [GOC:dph, GOC:mtg_heart, GOC:TermGenie, PMID:21419760] is_a: GO:2000136 ! regulation of cell proliferation involved in heart morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0061325 ! cell proliferation involved in outflow tract morphogenesis relationship: regulates GO:0061325 ! cell proliferation involved in outflow tract morphogenesis created_by: dph creation_date: 2013-02-20T20:30:26Z [Term] id: GO:1901964 name: positive regulation of cell proliferation involved in outflow tract morphogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis." [GOC:dph, GOC:mtg_heart, GOC:TermGenie, PMID:21419760] synonym: "activation of cell proliferation involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] synonym: "up regulation of cell proliferation involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of cell proliferation involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of cell proliferation involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] is_a: GO:1901963 ! regulation of cell proliferation involved in outflow tract morphogenesis is_a: GO:2000138 ! positive regulation of cell proliferation involved in heart morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0061325 ! cell proliferation involved in outflow tract morphogenesis relationship: positively_regulates GO:0061325 ! cell proliferation involved in outflow tract morphogenesis created_by: dph creation_date: 2013-02-20T20:30:31Z [Term] id: GO:1902017 name: regulation of cilium assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cilium assembly." [GOC:cilia, GOC:dph, GOC:TermGenie, PMID:17719545] synonym: "regulation of ciliogenesis" EXACT [GOC:TermGenie] synonym: "regulation of cilium biogenesis" RELATED [GOC:TermGenie] is_a: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly is_a: GO:1902115 ! regulation of organelle assembly intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060271 ! cilium assembly relationship: regulates GO:0060271 ! cilium assembly created_by: dph creation_date: 2013-03-26T18:10:51Z [Term] id: GO:1902018 name: negative regulation of cilium assembly namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cilium assembly." [GOC:cilia, GOC:dph, GOC:TermGenie, PMID:17719545] synonym: "down regulation of ciliogenesis" EXACT [GOC:TermGenie] synonym: "down regulation of cilium assembly" EXACT [GOC:TermGenie] synonym: "down regulation of cilium biogenesis" RELATED [GOC:TermGenie] synonym: "down-regulation of ciliogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of cilium assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of cilium biogenesis" RELATED [GOC:TermGenie] synonym: "downregulation of ciliogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of cilium assembly" EXACT [GOC:TermGenie] synonym: "downregulation of cilium biogenesis" RELATED [GOC:TermGenie] synonym: "inhibition of ciliogenesis" EXACT [GOC:TermGenie] synonym: "inhibition of cilium assembly" NARROW [GOC:TermGenie] synonym: "inhibition of cilium biogenesis" RELATED [GOC:TermGenie] synonym: "negative regulation of ciliogenesis" EXACT [GOC:TermGenie] synonym: "negative regulation of cilium biogenesis" RELATED [GOC:TermGenie] is_a: GO:0120033 ! negative regulation of plasma membrane bounded cell projection assembly is_a: GO:1902017 ! regulation of cilium assembly is_a: GO:1902116 ! negative regulation of organelle assembly intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060271 ! cilium assembly relationship: negatively_regulates GO:0060271 ! cilium assembly created_by: dph creation_date: 2013-03-26T18:10:56Z [Term] id: GO:1902019 name: regulation of cilium-dependent cell motility namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cilium-dependent cell motility." [GOC:cilia, GOC:jl, GOC:TermGenie] synonym: "regulation of ciliary cell motility" RELATED [] synonym: "regulation of cilium cell motility" EXACT [] is_a: GO:2000145 ! regulation of cell motility intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060285 ! cilium-dependent cell motility relationship: regulates GO:0060285 ! cilium-dependent cell motility created_by: jl creation_date: 2013-03-27T14:42:38Z [Term] id: GO:1902020 name: negative regulation of cilium-dependent cell motility namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cilium-dependent cell motility." [GOC:cilia, GOC:jl, GOC:TermGenie] synonym: "down regulation of ciliary cell motility" EXACT [GOC:TermGenie] synonym: "down-regulation of ciliary cell motility" EXACT [GOC:TermGenie] synonym: "downregulation of ciliary cell motility" EXACT [GOC:TermGenie] synonym: "inhibition of ciliary cell motility" NARROW [GOC:TermGenie] synonym: "negative regulation of ciliary cell motility" RELATED [] synonym: "negative regulation of cilium cell motility" EXACT [] is_a: GO:1902019 ! regulation of cilium-dependent cell motility is_a: GO:2000146 ! negative regulation of cell motility intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060285 ! cilium-dependent cell motility relationship: negatively_regulates GO:0060285 ! cilium-dependent cell motility created_by: jl creation_date: 2013-03-27T14:42:42Z [Term] id: GO:1902033 name: regulation of hematopoietic stem cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of hematopoietic stem cell proliferation." [GOC:TermGenie, PMID:23403623] synonym: "regulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0072091 ! regulation of stem cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0071425 ! hematopoietic stem cell proliferation relationship: regulates GO:0071425 ! hematopoietic stem cell proliferation created_by: ss creation_date: 2013-04-02T05:13:19Z [Term] id: GO:1902034 name: negative regulation of hematopoietic stem cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell proliferation." [GOC:TermGenie, PMID:23403623] synonym: "down regulation of hematopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "down regulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of hematopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of hematopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "inhibition of hematopoietic stem cell proliferation" NARROW [GOC:TermGenie] synonym: "inhibition of hemopoietic stem cell proliferation" NARROW [GOC:TermGenie] synonym: "negative regulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] is_a: GO:1902033 ! regulation of hematopoietic stem cell proliferation is_a: GO:1903707 ! negative regulation of hemopoiesis is_a: GO:2000647 ! negative regulation of stem cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0071425 ! hematopoietic stem cell proliferation relationship: negatively_regulates GO:0071425 ! hematopoietic stem cell proliferation created_by: ss creation_date: 2013-04-02T05:13:24Z [Term] id: GO:1902035 name: positive regulation of hematopoietic stem cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell proliferation." [GOC:TermGenie, PMID:23403623] synonym: "activation of hematopoietic stem cell proliferation" NARROW [GOC:TermGenie] synonym: "activation of hemopoietic stem cell proliferation" NARROW [GOC:TermGenie] synonym: "positive regulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of hematopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of hematopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of hematopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] is_a: GO:1902033 ! regulation of hematopoietic stem cell proliferation is_a: GO:2000648 ! positive regulation of stem cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0071425 ! hematopoietic stem cell proliferation relationship: positively_regulates GO:0071425 ! hematopoietic stem cell proliferation created_by: ss creation_date: 2013-04-02T05:13:31Z [Term] id: GO:1902036 name: regulation of hematopoietic stem cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of hematopoietic stem cell differentiation." [GOC:TermGenie, PMID:23403623] synonym: "regulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "regulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "regulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] is_a: GO:1901532 ! regulation of hematopoietic progenitor cell differentiation is_a: GO:2000736 ! regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060218 ! hematopoietic stem cell differentiation relationship: regulates GO:0060218 ! hematopoietic stem cell differentiation created_by: ss creation_date: 2013-04-02T05:19:09Z [Term] id: GO:1902037 name: negative regulation of hematopoietic stem cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell differentiation." [GOC:TermGenie, PMID:23403623] synonym: "down regulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of hematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of hematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of hematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of haematopoietic stem cell differentiation" NARROW [GOC:TermGenie] synonym: "inhibition of haemopoietic stem cell differentiation" NARROW [GOC:TermGenie] synonym: "inhibition of hematopoietic stem cell differentiation" NARROW [GOC:TermGenie] synonym: "inhibition of hemopoietic stem cell differentiation" NARROW [GOC:TermGenie] synonym: "negative regulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "negative regulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "negative regulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] is_a: GO:1901533 ! negative regulation of hematopoietic progenitor cell differentiation is_a: GO:1902036 ! regulation of hematopoietic stem cell differentiation is_a: GO:2000737 ! negative regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060218 ! hematopoietic stem cell differentiation relationship: negatively_regulates GO:0060218 ! hematopoietic stem cell differentiation created_by: ss creation_date: 2013-04-02T05:19:14Z [Term] id: GO:1902038 name: positive regulation of hematopoietic stem cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell differentiation." [GOC:TermGenie, PMID:23403623] synonym: "activation of haematopoietic stem cell differentiation" NARROW [GOC:TermGenie] synonym: "activation of haemopoietic stem cell differentiation" NARROW [GOC:TermGenie] synonym: "activation of hematopoietic stem cell differentiation" NARROW [GOC:TermGenie] synonym: "activation of hemopoietic stem cell differentiation" NARROW [GOC:TermGenie] synonym: "positive regulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "positive regulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "positive regulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of hematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of hematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of hematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] is_a: GO:1901534 ! positive regulation of hematopoietic progenitor cell differentiation is_a: GO:1902036 ! regulation of hematopoietic stem cell differentiation is_a: GO:2000738 ! positive regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060218 ! hematopoietic stem cell differentiation relationship: positively_regulates GO:0060218 ! hematopoietic stem cell differentiation created_by: ss creation_date: 2013-04-02T05:19:19Z [Term] id: GO:1902074 name: response to salt namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus." [GOC:mls, GOC:TermGenie, PMID:16666921] synonym: "response to salinity" NARROW [GOC:mls] is_a: GO:0042221 ! response to chemical intersection_of: GO:0050896 ! response to stimulus intersection_of: has_primary_input CHEBI:24866 ! salt relationship: has_primary_input CHEBI:24866 ! salt created_by: mls creation_date: 2013-04-22T15:41:57Z [Term] id: GO:1902093 name: positive regulation of flagellated sperm motility namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of flagellated sperm motility." [GOC:cilia, GOC:jh2, GOC:krc, GOC:TermGenie, PMID:7513657] synonym: "activation of sperm motility" NARROW [GOC:TermGenie] synonym: "activation of sperm movement" BROAD [GOC:TermGenie] synonym: "positive regulation of sperm motility" BROAD [] synonym: "positive regulation of sperm movement" BROAD [GOC:TermGenie] synonym: "up regulation of sperm motility" BROAD [GOC:TermGenie] synonym: "up regulation of sperm movement" BROAD [GOC:TermGenie] synonym: "up-regulation of sperm motility" BROAD [GOC:TermGenie] synonym: "up-regulation of sperm movement" BROAD [GOC:TermGenie] synonym: "upregulation of sperm motility" BROAD [GOC:TermGenie] synonym: "upregulation of sperm movement" BROAD [GOC:TermGenie] is_a: GO:0003353 ! positive regulation of cilium movement is_a: GO:1901317 ! regulation of flagellated sperm motility is_a: GO:2000155 ! positive regulation of cilium-dependent cell motility is_a: GO:2000243 ! positive regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030317 ! flagellated sperm motility relationship: positively_regulates GO:0030317 ! flagellated sperm motility created_by: bf creation_date: 2013-04-29T09:15:25Z [Term] id: GO:1902105 name: regulation of leukocyte differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of leukocyte differentiation." [GOC:add, GOC:TermGenie] synonym: "regulation of immune cell differentiation" EXACT [GOC:TermGenie] synonym: "regulation of leucocyte differentiation" EXACT [GOC:TermGenie] is_a: GO:1903706 ! regulation of hemopoiesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002521 ! leukocyte differentiation relationship: regulates GO:0002521 ! leukocyte differentiation created_by: pr creation_date: 2013-05-02T17:32:42Z [Term] id: GO:1902106 name: negative regulation of leukocyte differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte differentiation." [GOC:add, GOC:TermGenie] synonym: "down regulation of immune cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of leucocyte differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of leukocyte differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of immune cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of leucocyte differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of leukocyte differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of immune cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of leucocyte differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of leukocyte differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of immune cell differentiation" NARROW [GOC:TermGenie] synonym: "inhibition of leucocyte differentiation" NARROW [GOC:TermGenie] synonym: "inhibition of leukocyte differentiation" NARROW [GOC:TermGenie] synonym: "negative regulation of immune cell differentiation" EXACT [GOC:TermGenie] synonym: "negative regulation of leucocyte differentiation" EXACT [GOC:TermGenie] is_a: GO:1902105 ! regulation of leukocyte differentiation is_a: GO:1903707 ! negative regulation of hemopoiesis intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002521 ! leukocyte differentiation relationship: negatively_regulates GO:0002521 ! leukocyte differentiation created_by: pr creation_date: 2013-05-02T17:32:47Z [Term] id: GO:1902107 name: positive regulation of leukocyte differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of leukocyte differentiation." [GOC:add, GOC:TermGenie] synonym: "activation of immune cell differentiation" NARROW [GOC:TermGenie] synonym: "activation of leucocyte differentiation" NARROW [GOC:TermGenie] synonym: "activation of leukocyte differentiation" NARROW [GOC:TermGenie] synonym: "positive regulation of immune cell differentiation" EXACT [GOC:TermGenie] synonym: "positive regulation of leucocyte differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of immune cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of leucocyte differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of leukocyte differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of immune cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of leucocyte differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of leukocyte differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of immune cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of leucocyte differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of leukocyte differentiation" EXACT [GOC:TermGenie] is_a: GO:1902105 ! regulation of leukocyte differentiation is_a: GO:1903708 ! positive regulation of hemopoiesis intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002521 ! leukocyte differentiation relationship: positively_regulates GO:0002521 ! leukocyte differentiation created_by: pr creation_date: 2013-05-02T17:32:52Z [Term] id: GO:1902115 name: regulation of organelle assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of organelle assembly." [GOC:pr, GOC:TermGenie] is_a: GO:0033043 ! regulation of organelle organization is_a: GO:0044087 ! regulation of cellular component biogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0070925 ! organelle assembly relationship: regulates GO:0070925 ! organelle assembly created_by: pr creation_date: 2013-05-14T09:43:21Z [Term] id: GO:1902116 name: negative regulation of organelle assembly namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of organelle assembly." [GOC:pr, GOC:TermGenie] synonym: "down regulation of organelle assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of organelle assembly" EXACT [GOC:TermGenie] synonym: "downregulation of organelle assembly" EXACT [GOC:TermGenie] synonym: "inhibition of organelle assembly" NARROW [GOC:TermGenie] is_a: GO:0010639 ! negative regulation of organelle organization is_a: GO:1902115 ! regulation of organelle assembly intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0070925 ! organelle assembly relationship: negatively_regulates GO:0070925 ! organelle assembly created_by: pr creation_date: 2013-05-14T09:43:31Z [Term] id: GO:1902117 name: positive regulation of organelle assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of organelle assembly." [GOC:pr, GOC:TermGenie] synonym: "activation of organelle assembly" NARROW [GOC:TermGenie] synonym: "up regulation of organelle assembly" EXACT [GOC:TermGenie] synonym: "up-regulation of organelle assembly" EXACT [GOC:TermGenie] synonym: "upregulation of organelle assembly" EXACT [GOC:TermGenie] is_a: GO:0010638 ! positive regulation of organelle organization is_a: GO:0044089 ! positive regulation of cellular component biogenesis is_a: GO:1902115 ! regulation of organelle assembly intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0070925 ! organelle assembly relationship: positively_regulates GO:0070925 ! organelle assembly created_by: pr creation_date: 2013-05-14T09:43:36Z [Term] id: GO:1902217 name: erythrocyte apoptotic process namespace: biological_process def: "Any apoptotic process in an erythrocyte." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl, GOC:TermGenie, PMID:14569084] synonym: "erythrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "RBC apoptosis" NARROW [GOC:TermGenie] synonym: "RBC apoptotic process" EXACT [GOC:TermGenie] synonym: "red blood cell apoptosis" NARROW [GOC:TermGenie] synonym: "red blood cell apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0033028 ! myeloid cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000232 ! erythrocyte relationship: occurs_in CL:0000232 ! erythrocyte property_value: RO:0002161 NCBITaxon:4751 created_by: rl creation_date: 2013-06-13T10:02:29Z [Term] id: GO:1902250 name: regulation of erythrocyte apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of erythrocyte apoptotic process." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl, GOC:TermGenie, PMID:14569084] synonym: "regulation of erythrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "regulation of RBC apoptosis" NARROW [GOC:TermGenie] synonym: "regulation of RBC apoptotic process" EXACT [GOC:TermGenie] synonym: "regulation of red blood cell apoptosis" NARROW [GOC:TermGenie] synonym: "regulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0033032 ! regulation of myeloid cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1902217 ! erythrocyte apoptotic process relationship: regulates GO:1902217 ! erythrocyte apoptotic process created_by: rl creation_date: 2013-06-20T19:30:53Z [Term] id: GO:1902251 name: negative regulation of erythrocyte apoptotic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of erythrocyte apoptotic process." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl, GOC:TermGenie, PMID:14569084] synonym: "down regulation of erythrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of erythrocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "down regulation of RBC apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of RBC apoptotic process" EXACT [GOC:TermGenie] synonym: "down regulation of red blood cell apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of erythrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of erythrocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of RBC apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of RBC apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of red blood cell apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of erythrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of erythrocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of RBC apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of RBC apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of red blood cell apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] synonym: "inhibition of erythrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of erythrocyte apoptotic process" NARROW [GOC:TermGenie] synonym: "inhibition of RBC apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of RBC apoptotic process" NARROW [GOC:TermGenie] synonym: "inhibition of red blood cell apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of red blood cell apoptotic process" NARROW [GOC:TermGenie] synonym: "negative regulation of erythrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "negative regulation of RBC apoptosis" NARROW [GOC:TermGenie] synonym: "negative regulation of RBC apoptotic process" EXACT [GOC:TermGenie] synonym: "negative regulation of red blood cell apoptosis" NARROW [GOC:TermGenie] synonym: "negative regulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0033033 ! negative regulation of myeloid cell apoptotic process is_a: GO:1902250 ! regulation of erythrocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1902217 ! erythrocyte apoptotic process relationship: negatively_regulates GO:1902217 ! erythrocyte apoptotic process property_value: RO:0002161 NCBITaxon:4751 created_by: rl creation_date: 2013-06-20T19:30:59Z [Term] id: GO:1902252 name: positive regulation of erythrocyte apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of erythrocyte apoptotic process." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl, GOC:TermGenie, PMID:14569084] synonym: "activation of erythrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "activation of erythrocyte apoptotic process" NARROW [GOC:TermGenie] synonym: "activation of RBC apoptosis" NARROW [GOC:TermGenie] synonym: "activation of RBC apoptotic process" NARROW [GOC:TermGenie] synonym: "activation of red blood cell apoptosis" NARROW [GOC:TermGenie] synonym: "activation of red blood cell apoptotic process" NARROW [GOC:TermGenie] synonym: "positive regulation of erythrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "positive regulation of RBC apoptosis" NARROW [GOC:TermGenie] synonym: "positive regulation of RBC apoptotic process" EXACT [GOC:TermGenie] synonym: "positive regulation of red blood cell apoptosis" NARROW [GOC:TermGenie] synonym: "positive regulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of erythrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of erythrocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of RBC apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of RBC apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of red blood cell apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of erythrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of erythrocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of RBC apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of RBC apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of red blood cell apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of erythrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of erythrocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of RBC apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of RBC apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of red blood cell apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0033034 ! positive regulation of myeloid cell apoptotic process is_a: GO:1902250 ! regulation of erythrocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1902217 ! erythrocyte apoptotic process relationship: positively_regulates GO:1902217 ! erythrocyte apoptotic process property_value: RO:0002161 NCBITaxon:4751 created_by: rl creation_date: 2013-06-20T19:31:04Z [Term] id: GO:1902256 name: regulation of apoptotic process involved in outflow tract morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis." [GOC:dph, GOC:mtg_apoptosis, GOC:TermGenie, PMID:16839542] synonym: "regulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] is_a: GO:1902337 ! regulation of apoptotic process involved in morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003275 ! apoptotic process involved in outflow tract morphogenesis relationship: regulates GO:0003275 ! apoptotic process involved in outflow tract morphogenesis created_by: dph creation_date: 2013-06-24T19:12:24Z [Term] id: GO:1902257 name: negative regulation of apoptotic process involved in outflow tract morphogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis." [GOC:dph, GOC:mtg_apoptosis, GOC:TermGenie, PMID:16839542] synonym: "down regulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] synonym: "down regulation of apoptotic process involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptotic process involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] synonym: "downregulation of apoptotic process involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "inhibition of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic process involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] synonym: "negative regulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] is_a: GO:1902256 ! regulation of apoptotic process involved in outflow tract morphogenesis is_a: GO:1902338 ! negative regulation of apoptotic process involved in morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0003275 ! apoptotic process involved in outflow tract morphogenesis relationship: negatively_regulates GO:0003275 ! apoptotic process involved in outflow tract morphogenesis created_by: dph creation_date: 2013-06-24T19:12:30Z [Term] id: GO:1902258 name: positive regulation of apoptotic process involved in outflow tract morphogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis." [GOC:dph, GOC:mtg_apoptosis, GOC:TermGenie, PMID:16839542] synonym: "activation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] synonym: "activation of apoptotic process involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] synonym: "positive regulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] synonym: "up regulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] synonym: "up regulation of apoptotic process involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptotic process involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] synonym: "upregulation of apoptotic process involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] is_a: GO:1902256 ! regulation of apoptotic process involved in outflow tract morphogenesis is_a: GO:1902339 ! positive regulation of apoptotic process involved in morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0003275 ! apoptotic process involved in outflow tract morphogenesis relationship: positively_regulates GO:0003275 ! apoptotic process involved in outflow tract morphogenesis created_by: dph creation_date: 2013-06-24T19:12:42Z [Term] id: GO:1902262 name: apoptotic process involved in blood vessel morphogenesis namespace: biological_process def: "Any apoptotic process that is involved in blood vessel morphogenesis." [GOC:dph, GOC:mtg_apoptosis, GOC:TermGenie, PMID:16163358] synonym: "apoptosis involved in patterning of blood vessels" NARROW [GOC:TermGenie] synonym: "apoptotic cell death involved in patterning of blood vessels" EXACT [GOC:TermGenie] synonym: "apoptotic program involved in patterning of blood vessels" NARROW [GOC:TermGenie] synonym: "apoptotic programmed cell death involved in patterning of blood vessels" EXACT [GOC:TermGenie] synonym: "programmed cell death by apoptosis involved in patterning of blood vessels" EXACT [GOC:TermGenie] synonym: "signaling (initiator) caspase activity involved in patterning of blood vessels" RELATED [GOC:TermGenie] synonym: "type I programmed cell death involved in patterning of blood vessels" NARROW [GOC:TermGenie] is_a: GO:0060561 ! apoptotic process involved in morphogenesis intersection_of: GO:0006915 ! apoptotic process intersection_of: part_of GO:0048514 ! blood vessel morphogenesis relationship: part_of GO:0048514 ! blood vessel morphogenesis created_by: dph creation_date: 2013-06-25T16:16:00Z [Term] id: GO:1902275 name: regulation of chromatin organization namespace: biological_process alt_id: GO:0001672 alt_id: GO:1903308 def: "Any process that modulates the frequency, rate or extent of chromatin organization." [GO_REF:0000058, GOC:bf, GOC:TermGenie, GOC:vw, PMID:18314879] synonym: "regulation of chromatin assembly or disassembly" RELATED [] synonym: "regulation of chromatin assembly/disassembly" RELATED [] synonym: "regulation of chromatin modification" RELATED [] synonym: "regulation of chromatin organisation" EXACT [GOC:TermGenie] synonym: "regulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006325 ! chromatin organization relationship: regulates GO:0006325 ! chromatin organization created_by: bf creation_date: 2013-07-01T13:21:52Z [Term] id: GO:1902305 name: regulation of sodium ion transmembrane transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of sodium ion transmembrane transport." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:18591664] synonym: "regulation of sodium ion membrane transport" EXACT [GOC:TermGenie] is_a: GO:0002028 ! regulation of sodium ion transport is_a: GO:1904062 ! regulation of monoatomic cation transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0035725 ! sodium ion transmembrane transport relationship: regulates GO:0035725 ! sodium ion transmembrane transport created_by: rl creation_date: 2013-07-18T13:33:53Z [Term] id: GO:1902306 name: negative regulation of sodium ion transmembrane transport namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transport." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:18591664] synonym: "down regulation of sodium ion membrane transport" EXACT [GOC:TermGenie] synonym: "down regulation of sodium ion transmembrane transport" EXACT [GOC:TermGenie] synonym: "down-regulation of sodium ion membrane transport" EXACT [GOC:TermGenie] synonym: "down-regulation of sodium ion transmembrane transport" EXACT [GOC:TermGenie] synonym: "downregulation of sodium ion membrane transport" EXACT [GOC:TermGenie] synonym: "downregulation of sodium ion transmembrane transport" EXACT [GOC:TermGenie] synonym: "inhibition of sodium ion membrane transport" NARROW [GOC:TermGenie] synonym: "inhibition of sodium ion transmembrane transport" NARROW [GOC:TermGenie] synonym: "negative regulation of sodium ion membrane transport" EXACT [GOC:TermGenie] is_a: GO:0010766 ! negative regulation of sodium ion transport is_a: GO:1902305 ! regulation of sodium ion transmembrane transport is_a: GO:1904063 ! negative regulation of cation transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0035725 ! sodium ion transmembrane transport relationship: negatively_regulates GO:0035725 ! sodium ion transmembrane transport created_by: rl creation_date: 2013-07-18T13:34:01Z [Term] id: GO:1902307 name: positive regulation of sodium ion transmembrane transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transport." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:18591664] synonym: "activation of sodium ion membrane transport" NARROW [GOC:TermGenie] synonym: "activation of sodium ion transmembrane transport" NARROW [GOC:TermGenie] synonym: "positive regulation of sodium ion membrane transport" EXACT [GOC:TermGenie] synonym: "up regulation of sodium ion membrane transport" EXACT [GOC:TermGenie] synonym: "up regulation of sodium ion transmembrane transport" EXACT [GOC:TermGenie] synonym: "up-regulation of sodium ion membrane transport" EXACT [GOC:TermGenie] synonym: "up-regulation of sodium ion transmembrane transport" EXACT [GOC:TermGenie] synonym: "upregulation of sodium ion membrane transport" EXACT [GOC:TermGenie] synonym: "upregulation of sodium ion transmembrane transport" EXACT [GOC:TermGenie] is_a: GO:0010765 ! positive regulation of sodium ion transport is_a: GO:1902305 ! regulation of sodium ion transmembrane transport is_a: GO:1904064 ! positive regulation of cation transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0035725 ! sodium ion transmembrane transport relationship: positively_regulates GO:0035725 ! sodium ion transmembrane transport created_by: rl creation_date: 2013-07-18T13:34:18Z [Term] id: GO:1902337 name: regulation of apoptotic process involved in morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of apoptotic process involved in morphogenesis." [GOC:sart, GOC:TermGenie, PMID:12202035] synonym: "regulation of apoptosis involved in development" RELATED [GOC:TermGenie] synonym: "regulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] synonym: "regulation of morphogenetic apoptosis" RELATED [GOC:TermGenie] is_a: GO:1904748 ! regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060561 ! apoptotic process involved in morphogenesis relationship: regulates GO:0060561 ! apoptotic process involved in morphogenesis created_by: sart creation_date: 2013-07-29T15:03:16Z [Term] id: GO:1902338 name: negative regulation of apoptotic process involved in morphogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in morphogenesis." [GOC:sart, GOC:TermGenie, PMID:12202035] synonym: "down regulation of apoptosis involved in development" RELATED [GOC:TermGenie] synonym: "down regulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] synonym: "down regulation of apoptotic process involved in morphogenesis" EXACT [GOC:TermGenie] synonym: "down regulation of morphogenetic apoptosis" RELATED [GOC:TermGenie] synonym: "down-regulation of apoptosis involved in development" RELATED [GOC:TermGenie] synonym: "down-regulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptotic process involved in morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of morphogenetic apoptosis" RELATED [GOC:TermGenie] synonym: "downregulation of apoptosis involved in development" RELATED [GOC:TermGenie] synonym: "downregulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] synonym: "downregulation of apoptotic process involved in morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of morphogenetic apoptosis" RELATED [GOC:TermGenie] synonym: "inhibition of apoptosis involved in development" RELATED [GOC:TermGenie] synonym: "inhibition of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic process involved in morphogenesis" NARROW [GOC:TermGenie] synonym: "inhibition of morphogenetic apoptosis" RELATED [GOC:TermGenie] synonym: "negative regulation of apoptosis involved in development" RELATED [GOC:TermGenie] synonym: "negative regulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] synonym: "negative regulation of morphogenetic apoptosis" RELATED [GOC:TermGenie] is_a: GO:1902337 ! regulation of apoptotic process involved in morphogenesis is_a: GO:1904746 ! negative regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060561 ! apoptotic process involved in morphogenesis relationship: negatively_regulates GO:0060561 ! apoptotic process involved in morphogenesis created_by: sart creation_date: 2013-07-29T15:03:25Z [Term] id: GO:1902339 name: positive regulation of apoptotic process involved in morphogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in morphogenesis." [GOC:sart, GOC:TermGenie, PMID:12202035] synonym: "activation of apoptosis involved in development" RELATED [GOC:TermGenie] synonym: "activation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] synonym: "activation of apoptotic process involved in morphogenesis" NARROW [GOC:TermGenie] synonym: "activation of morphogenetic apoptosis" RELATED [GOC:TermGenie] synonym: "positive regulation of apoptosis involved in development" RELATED [GOC:TermGenie] synonym: "positive regulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] synonym: "positive regulation of morphogenetic apoptosis" RELATED [GOC:TermGenie] synonym: "up regulation of apoptosis involved in development" RELATED [GOC:TermGenie] synonym: "up regulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] synonym: "up regulation of apoptotic process involved in morphogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of morphogenetic apoptosis" RELATED [GOC:TermGenie] synonym: "up-regulation of apoptosis involved in development" RELATED [GOC:TermGenie] synonym: "up-regulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptotic process involved in morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of morphogenetic apoptosis" RELATED [GOC:TermGenie] synonym: "upregulation of apoptosis involved in development" RELATED [GOC:TermGenie] synonym: "upregulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] synonym: "upregulation of apoptotic process involved in morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of morphogenetic apoptosis" RELATED [GOC:TermGenie] is_a: GO:1902337 ! regulation of apoptotic process involved in morphogenesis is_a: GO:1904747 ! positive regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060561 ! apoptotic process involved in morphogenesis relationship: positively_regulates GO:0060561 ! apoptotic process involved in morphogenesis created_by: sart creation_date: 2013-07-29T15:03:33Z [Term] id: GO:1902340 name: negative regulation of chromosome condensation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of chromosome condensation." [GOC:TermGenie, PMID:23219725] synonym: "down regulation of chromosome condensation" EXACT [GOC:TermGenie] synonym: "down regulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie] synonym: "down regulation of nuclear chromosome condensation" EXACT [GOC:TermGenie] synonym: "down-regulation of chromosome condensation" EXACT [GOC:TermGenie] synonym: "down-regulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie] synonym: "down-regulation of nuclear chromosome condensation" EXACT [GOC:TermGenie] synonym: "downregulation of chromosome condensation" EXACT [GOC:TermGenie] synonym: "downregulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie] synonym: "downregulation of nuclear chromosome condensation" EXACT [GOC:TermGenie] synonym: "inhibition of chromosome condensation" NARROW [GOC:TermGenie] synonym: "inhibition of eukaryotic chromosome condensation" NARROW [GOC:TermGenie] synonym: "inhibition of nuclear chromosome condensation" NARROW [GOC:TermGenie] synonym: "negative regulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie] synonym: "negative regulation of nuclear chromosome condensation" EXACT [GOC:TermGenie] is_a: GO:0060623 ! regulation of chromosome condensation is_a: GO:2001251 ! negative regulation of chromosome organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030261 ! chromosome condensation relationship: negatively_regulates GO:0030261 ! chromosome condensation created_by: dgf creation_date: 2013-07-29T20:54:14Z [Term] id: GO:1902358 name: sulfate transmembrane transport namespace: biological_process def: "The directed movement of sulfate across a membrane." [GOC:dph, GOC:TermGenie, PMID:9055073] is_a: GO:0008272 ! sulfate transport is_a: GO:0098661 ! inorganic anion transmembrane transport intersection_of: GO:0055085 ! transmembrane transport intersection_of: has_primary_input CHEBI:16189 ! sulfate created_by: dph creation_date: 2013-08-14T14:46:04Z [Term] id: GO:1902369 name: negative regulation of RNA catabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of RNA catabolic process." [GOC:bf, GOC:TermGenie, PMID:16640457] synonym: "down regulation of RNA breakdown" EXACT [GOC:TermGenie] synonym: "down regulation of RNA catabolic process" EXACT [GOC:TermGenie] synonym: "down regulation of RNA catabolism" EXACT [GOC:TermGenie] synonym: "down regulation of RNA degradation" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA breakdown" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA catabolic process" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA catabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA degradation" EXACT [GOC:TermGenie] synonym: "downregulation of RNA breakdown" EXACT [GOC:TermGenie] synonym: "downregulation of RNA catabolic process" EXACT [GOC:TermGenie] synonym: "downregulation of RNA catabolism" EXACT [GOC:TermGenie] synonym: "downregulation of RNA degradation" EXACT [GOC:TermGenie] synonym: "inhibition of RNA breakdown" NARROW [GOC:TermGenie] synonym: "inhibition of RNA catabolic process" NARROW [GOC:TermGenie] synonym: "inhibition of RNA catabolism" NARROW [GOC:TermGenie] synonym: "inhibition of RNA degradation" NARROW [GOC:TermGenie] synonym: "negative regulation of RNA breakdown" EXACT [GOC:TermGenie] synonym: "negative regulation of RNA catabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of RNA degradation" EXACT [GOC:TermGenie] is_a: GO:0031330 ! negative regulation of cellular catabolic process is_a: GO:0051253 ! negative regulation of RNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006401 ! RNA catabolic process relationship: negatively_regulates GO:0006401 ! RNA catabolic process created_by: bf creation_date: 2013-08-22T14:59:39Z [Term] id: GO:1902414 name: protein localization to cell junction namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within a cell junction." [GOC:TermGenie, PMID:18332111] synonym: "protein localisation in cell junction" EXACT [GOC:TermGenie] synonym: "protein localisation to cell junction" EXACT [GOC:TermGenie] synonym: "protein localization in cell junction" EXACT [GOC:TermGenie] is_a: GO:0008104 ! protein localization intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0030054 ! cell junction relationship: has_target_end_location GO:0030054 ! cell junction created_by: tb creation_date: 2013-09-13T16:55:57Z [Term] id: GO:1902455 name: negative regulation of stem cell population maintenance namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of stem cell population maintenance." [GOC:hjd, GOC:TermGenie, PMID:22969033] synonym: "down regulation of maintenance of pluripotency" RELATED [GOC:TermGenie] synonym: "down regulation of stem cell maintenance" EXACT [GOC:TermGenie] synonym: "down-regulation of maintenance of pluripotency" RELATED [GOC:TermGenie] synonym: "down-regulation of stem cell maintenance" EXACT [GOC:TermGenie] synonym: "downregulation of maintenance of pluripotency" RELATED [GOC:TermGenie] synonym: "downregulation of stem cell maintenance" EXACT [GOC:TermGenie] synonym: "inhibition of maintenance of pluripotency" RELATED [GOC:TermGenie] synonym: "inhibition of stem cell maintenance" NARROW [GOC:TermGenie] synonym: "negative regulation of maintenance of pluripotency" RELATED [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:2000036 ! regulation of stem cell population maintenance intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0019827 ! stem cell population maintenance relationship: negatively_regulates GO:0019827 ! stem cell population maintenance created_by: cjm creation_date: 2013-10-16T22:19:17Z [Term] id: GO:1902459 name: positive regulation of stem cell population maintenance namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of stem cell population maintenance." [GOC:hjd, GOC:TermGenie, PMID:22969033] synonym: "activation of maintenance of pluripotency" RELATED [GOC:TermGenie] synonym: "activation of stem cell maintenance" NARROW [GOC:TermGenie] synonym: "positive regulation of maintenance of pluripotency" RELATED [GOC:TermGenie] synonym: "up regulation of maintenance of pluripotency" RELATED [GOC:TermGenie] synonym: "up regulation of stem cell maintenance" EXACT [GOC:TermGenie] synonym: "up-regulation of maintenance of pluripotency" RELATED [GOC:TermGenie] synonym: "up-regulation of stem cell maintenance" EXACT [GOC:TermGenie] synonym: "upregulation of maintenance of pluripotency" RELATED [GOC:TermGenie] synonym: "upregulation of stem cell maintenance" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:2000036 ! regulation of stem cell population maintenance intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0019827 ! stem cell population maintenance relationship: positively_regulates GO:0019827 ! stem cell population maintenance created_by: cjm creation_date: 2013-10-16T22:27:47Z [Term] id: GO:1902463 name: protein localization to cell leading edge namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within a cell leading edge." [GOC:lb, GOC:TermGenie, PMID:21543326] synonym: "protein localisation in cell leading edge" EXACT [GOC:TermGenie] synonym: "protein localisation to cell leading edge" EXACT [GOC:TermGenie] synonym: "protein localization in cell leading edge" EXACT [GOC:TermGenie] is_a: GO:0008104 ! protein localization intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0031252 ! cell leading edge relationship: has_target_end_location GO:0031252 ! cell leading edge created_by: jl creation_date: 2013-10-22T12:36:07Z [Term] id: GO:1902473 name: regulation of protein localization to synapse namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein localization to synapse." [GOC:kmv, GOC:TermGenie, PMID:22588719] synonym: "regulation of protein localisation to synapse" EXACT [GOC:TermGenie] is_a: GO:0032880 ! regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0035418 ! protein localization to synapse relationship: regulates GO:0035418 ! protein localization to synapse created_by: kmv creation_date: 2013-10-25T15:09:09Z [Term] id: GO:1902474 name: positive regulation of protein localization to synapse namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein localization to synapse." [GOC:kmv, GOC:TermGenie, PMID:22588719] synonym: "activation of protein localisation to synapse" NARROW [GOC:TermGenie] synonym: "activation of protein localization to synapse" NARROW [GOC:TermGenie] synonym: "positive regulation of protein localisation to synapse" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation to synapse" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization to synapse" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation to synapse" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to synapse" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation to synapse" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to synapse" EXACT [GOC:TermGenie] is_a: GO:1902473 ! regulation of protein localization to synapse is_a: GO:1903829 ! positive regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0035418 ! protein localization to synapse relationship: positively_regulates GO:0035418 ! protein localization to synapse created_by: kmv creation_date: 2013-10-25T15:09:18Z [Term] id: GO:1902484 name: Sertoli cell apoptotic process namespace: biological_process def: "Any apoptotic process in a Sertoli cell." [GOC:ic, GOC:TermGenie, PMID:17761895] synonym: "Sertoli cell apoptosis" NARROW [GOC:TermGenie] is_a: GO:1904019 ! epithelial cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000216 ! Sertoli cell relationship: occurs_in CL:0000216 ! Sertoli cell created_by: pr creation_date: 2013-11-06T11:27:34Z [Term] id: GO:1902488 name: cholangiocyte apoptotic process namespace: biological_process def: "Any apoptotic process in a cholangiocyte." [GOC:TermGenie, PMID:22961800] synonym: "cholangiocyte apoptosis" NARROW [GOC:TermGenie] synonym: "epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] synonym: "epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] is_a: GO:1904019 ! epithelial cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:1000488 ! cholangiocyte relationship: occurs_in CL:1000488 ! cholangiocyte created_by: cls creation_date: 2013-11-12T15:30:08Z [Term] id: GO:1902489 name: hepatoblast apoptotic process namespace: biological_process def: "Any apoptotic process in a hepatoblast." [GOC:TermGenie, PMID:22412967] synonym: "hepatoblast apoptosis" NARROW [GOC:TermGenie] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0005026 ! hepatoblast relationship: occurs_in CL:0005026 ! hepatoblast created_by: cls creation_date: 2013-11-12T17:02:52Z [Term] id: GO:1902490 name: regulation of sperm capacitation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of sperm capacitation." [GOC:hjd, GOC:TermGenie, PMID:22539676] synonym: "regulation of sperm activation" RELATED [GOC:TermGenie] is_a: GO:0051239 ! regulation of multicellular organismal process is_a: GO:1903429 ! regulation of cell maturation is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048240 ! sperm capacitation relationship: regulates GO:0048240 ! sperm capacitation created_by: hjd creation_date: 2013-11-12T21:17:03Z [Term] id: GO:1902491 name: negative regulation of sperm capacitation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of sperm capacitation." [GOC:hjd, GOC:TermGenie, PMID:22539676] synonym: "down regulation of sperm activation" RELATED [GOC:TermGenie] synonym: "down regulation of sperm capacitation" EXACT [GOC:TermGenie] synonym: "down-regulation of sperm activation" RELATED [GOC:TermGenie] synonym: "down-regulation of sperm capacitation" EXACT [GOC:TermGenie] synonym: "downregulation of sperm activation" RELATED [GOC:TermGenie] synonym: "downregulation of sperm capacitation" EXACT [GOC:TermGenie] synonym: "inhibition of sperm activation" RELATED [GOC:TermGenie] synonym: "inhibition of sperm capacitation" NARROW [GOC:TermGenie] synonym: "negative regulation of sperm activation" RELATED [GOC:TermGenie] is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1902490 ! regulation of sperm capacitation is_a: GO:1903430 ! negative regulation of cell maturation is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048240 ! sperm capacitation relationship: negatively_regulates GO:0048240 ! sperm capacitation created_by: hjd creation_date: 2013-11-12T21:17:12Z [Term] id: GO:1902492 name: positive regulation of sperm capacitation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of sperm capacitation." [GOC:hjd, GOC:TermGenie, PMID:22539676] synonym: "activation of sperm activation" RELATED [GOC:TermGenie] synonym: "activation of sperm capacitation" NARROW [GOC:TermGenie] synonym: "positive regulation of sperm activation" RELATED [GOC:TermGenie] synonym: "up regulation of sperm activation" RELATED [GOC:TermGenie] synonym: "up regulation of sperm capacitation" EXACT [GOC:TermGenie] synonym: "up-regulation of sperm activation" RELATED [GOC:TermGenie] synonym: "up-regulation of sperm capacitation" EXACT [GOC:TermGenie] synonym: "upregulation of sperm activation" RELATED [GOC:TermGenie] synonym: "upregulation of sperm capacitation" EXACT [GOC:TermGenie] is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1902490 ! regulation of sperm capacitation is_a: GO:1903431 ! positive regulation of cell maturation is_a: GO:2000243 ! positive regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048240 ! sperm capacitation relationship: positively_regulates GO:0048240 ! sperm capacitation created_by: hjd creation_date: 2013-11-12T21:17:21Z [Term] id: GO:1902494 name: catalytic complex namespace: cellular_component def: "A protein complex which is capable of catalytic activity." [GOC:bhm, GOC:TermGenie, PMID:8077207] subset: goslim_metagenomics synonym: "enzyme complex" EXACT [GOC:bhm, GOC:jl] is_a: GO:0032991 ! protein-containing complex intersection_of: GO:0032991 ! protein-containing complex intersection_of: capable_of GO:0003824 ! catalytic activity relationship: capable_of GO:0003824 ! catalytic activity property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19980" xsd:anyURI created_by: bhm creation_date: 2013-11-13T16:18:47Z [Term] id: GO:1902495 name: transmembrane transporter complex namespace: cellular_component def: "A transmembrane protein complex which enables the transfer of a substance from one side of a membrane to the other." [GOC:bhm, GOC:TermGenie, PMID:18024586] is_a: GO:0098796 ! membrane protein complex is_a: GO:1990351 ! transporter complex intersection_of: GO:0032991 ! protein-containing complex intersection_of: capable_of GO:0022857 ! transmembrane transporter activity relationship: capable_of GO:0022857 ! transmembrane transporter activity created_by: bhm creation_date: 2013-11-13T16:23:04Z [Term] id: GO:1902510 name: regulation of apoptotic DNA fragmentation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of apoptotic DNA fragmentation." [GOC:hjd, GOC:TermGenie, PMID:15572351, PMID:15723341] comment: DNA fragmentation in response to apoptotic signals is achieved through the activity of apoptotic nucleases (see GO:0006309 'apoptotic DNA fragmentation'). Gene products involved in compartmentalization of such nucleases and in activation or repression of their enzymatic activity should be annotated to the regulation term GO:1902510 'regulation of apoptotic DNA fragmentation' or to one of its children (see PMID:15723341). synonym: "regulation of chromatinolysis" BROAD [GOC:TermGenie] synonym: "regulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie] synonym: "regulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie] synonym: "regulation of DNA fragmentation" BROAD [GOC:TermGenie] synonym: "regulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie] synonym: "regulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie] is_a: GO:1903624 ! regulation of DNA catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006309 ! apoptotic DNA fragmentation relationship: regulates GO:0006309 ! apoptotic DNA fragmentation created_by: hjd creation_date: 2013-11-15T18:28:32Z [Term] id: GO:1902511 name: negative regulation of apoptotic DNA fragmentation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic DNA fragmentation." [GOC:hjd, GOC:TermGenie, PMID:15572351] synonym: "down regulation of apoptotic DNA fragmentation" EXACT [GOC:TermGenie] synonym: "down regulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie] synonym: "down regulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie] synonym: "down regulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie] synonym: "down regulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic DNA fragmentation" EXACT [GOC:TermGenie] synonym: "down-regulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie] synonym: "down-regulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie] synonym: "down-regulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie] synonym: "down-regulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic DNA fragmentation" EXACT [GOC:TermGenie] synonym: "downregulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie] synonym: "downregulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie] synonym: "downregulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie] synonym: "downregulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie] synonym: "inhibition of apoptotic DNA fragmentation" NARROW [GOC:TermGenie] synonym: "inhibition of DNA catabolic process during apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of DNA catabolism during apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of DNA fragmentation involved in apoptotic nuclear change" NARROW [GOC:TermGenie] synonym: "inhibition of endonucleolytic DNA catabolic process involved in apoptosis" NARROW [GOC:TermGenie] synonym: "negative regulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie] synonym: "negative regulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie] synonym: "negative regulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie] synonym: "negative regulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie] is_a: GO:1902510 ! regulation of apoptotic DNA fragmentation is_a: GO:1903625 ! negative regulation of DNA catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006309 ! apoptotic DNA fragmentation relationship: negatively_regulates GO:0006309 ! apoptotic DNA fragmentation created_by: hjd creation_date: 2013-11-15T18:28:41Z [Term] id: GO:1902512 name: positive regulation of apoptotic DNA fragmentation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of apoptotic DNA fragmentation." [GOC:hjd, GOC:TermGenie, PMID:15572351] synonym: "activation of apoptotic DNA fragmentation" NARROW [GOC:TermGenie] synonym: "activation of DNA catabolic process during apoptosis" NARROW [GOC:TermGenie] synonym: "activation of DNA catabolism during apoptosis" NARROW [GOC:TermGenie] synonym: "activation of DNA fragmentation involved in apoptotic nuclear change" NARROW [GOC:TermGenie] synonym: "activation of endonucleolytic DNA catabolic process involved in apoptosis" NARROW [GOC:TermGenie] synonym: "positive regulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie] synonym: "positive regulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie] synonym: "positive regulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie] synonym: "positive regulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic DNA fragmentation" EXACT [GOC:TermGenie] synonym: "up regulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie] synonym: "up regulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie] synonym: "up regulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie] synonym: "up regulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic DNA fragmentation" EXACT [GOC:TermGenie] synonym: "up-regulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie] synonym: "up-regulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie] synonym: "up-regulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie] synonym: "up-regulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic DNA fragmentation" EXACT [GOC:TermGenie] synonym: "upregulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie] synonym: "upregulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie] synonym: "upregulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie] synonym: "upregulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie] is_a: GO:1902510 ! regulation of apoptotic DNA fragmentation is_a: GO:1903626 ! positive regulation of DNA catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006309 ! apoptotic DNA fragmentation relationship: positively_regulates GO:0006309 ! apoptotic DNA fragmentation created_by: hjd creation_date: 2013-11-15T18:28:50Z [Term] id: GO:1902513 name: regulation of organelle transport along microtubule namespace: biological_process def: "Any process that modulates the frequency, rate or extent of organelle transport along microtubule." [GOC:dph, GOC:TermGenie, PMID:21147087] synonym: "regulation of microtubule-based organelle localization" EXACT [GOC:TermGenie] is_a: GO:0032386 ! regulation of intracellular transport is_a: GO:0060632 ! regulation of microtubule-based movement intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0072384 ! organelle transport along microtubule relationship: regulates GO:0072384 ! organelle transport along microtubule created_by: dph creation_date: 2013-11-15T20:15:17Z [Term] id: GO:1902531 name: regulation of intracellular signal transduction namespace: biological_process alt_id: GO:0010627 def: "Any process that modulates the frequency, rate or extent of intracellular signal transduction." [GOC:dph, GOC:signaling, GOC:tb, GOC:TermGenie] synonym: "regulation of intracellular protein kinase cascade" NARROW [] synonym: "regulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie] synonym: "regulation of intracellular signaling cascade" EXACT [GOC:TermGenie] synonym: "regulation of intracellular signaling chain" EXACT [GOC:TermGenie] synonym: "regulation of intracellular signaling pathway" RELATED [GOC:TermGenie] synonym: "regulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "regulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie] is_a: GO:0009966 ! regulation of signal transduction intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0035556 ! intracellular signal transduction relationship: regulates GO:0035556 ! intracellular signal transduction created_by: bf creation_date: 2013-12-02T11:32:52Z [Term] id: GO:1902532 name: negative regulation of intracellular signal transduction namespace: biological_process alt_id: GO:0010741 def: "Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction." [GOC:dph, GOC:signaling, GOC:tb, GOC:TermGenie] synonym: "down regulation of intracellular signal transduction" EXACT [GOC:TermGenie] synonym: "down regulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie] synonym: "down regulation of intracellular signaling cascade" NARROW [GOC:TermGenie] synonym: "down regulation of intracellular signaling chain" EXACT [GOC:TermGenie] synonym: "down regulation of intracellular signaling pathway" RELATED [GOC:TermGenie] synonym: "down regulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "down regulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie] synonym: "down-regulation of intracellular signal transduction" EXACT [GOC:TermGenie] synonym: "down-regulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie] synonym: "down-regulation of intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "down-regulation of intracellular signaling chain" EXACT [GOC:TermGenie] synonym: "down-regulation of intracellular signaling pathway" RELATED [GOC:TermGenie] synonym: "down-regulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "down-regulation of signal transmission via intracellular cascade" RELATED [GOC:TermGenie] synonym: "downregulation of intracellular signal transduction" EXACT [GOC:TermGenie] synonym: "downregulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie] synonym: "downregulation of intracellular signaling cascade" NARROW [GOC:TermGenie] synonym: "downregulation of intracellular signaling chain" EXACT [GOC:TermGenie] synonym: "downregulation of intracellular signaling pathway" RELATED [GOC:TermGenie] synonym: "downregulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "downregulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie] synonym: "inhibition of intracellular signal transduction" NARROW [GOC:TermGenie] synonym: "inhibition of intracellular signal transduction pathway" NARROW [GOC:TermGenie] synonym: "inhibition of intracellular signaling cascade" NARROW [GOC:TermGenie] synonym: "inhibition of intracellular signaling chain" NARROW [GOC:TermGenie] synonym: "inhibition of intracellular signaling pathway" RELATED [GOC:TermGenie] synonym: "inhibition of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "inhibition of signal transmission via intracellular cascade" NARROW [GOC:TermGenie] synonym: "negative regulation of intracellular protein kinase cascade" EXACT [] synonym: "negative regulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie] synonym: "negative regulation of intracellular signaling cascade" EXACT [GOC:TermGenie] synonym: "negative regulation of intracellular signaling chain" EXACT [GOC:TermGenie] synonym: "negative regulation of intracellular signaling pathway" RELATED [GOC:TermGenie] synonym: "negative regulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "negative regulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie] is_a: GO:0009968 ! negative regulation of signal transduction is_a: GO:1902531 ! regulation of intracellular signal transduction intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0035556 ! intracellular signal transduction relationship: negatively_regulates GO:0035556 ! intracellular signal transduction created_by: bf creation_date: 2013-12-02T11:33:01Z [Term] id: GO:1902533 name: positive regulation of intracellular signal transduction namespace: biological_process alt_id: GO:0010740 def: "Any process that activates or increases the frequency, rate or extent of intracellular signal transduction." [GOC:BHF, GOC:dph, GOC:signaling, GOC:tb, GOC:TermGenie] synonym: "activation of intracellular signal transduction" NARROW [GOC:TermGenie] synonym: "activation of intracellular signal transduction pathway" NARROW [GOC:TermGenie] synonym: "activation of intracellular signaling cascade" NARROW [GOC:TermGenie] synonym: "activation of intracellular signaling chain" NARROW [GOC:TermGenie] synonym: "activation of intracellular signaling pathway" RELATED [GOC:TermGenie] synonym: "activation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "activation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie] synonym: "positive regulation of intracellular protein kinase cascade" NARROW [] synonym: "positive regulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie] synonym: "positive regulation of intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "positive regulation of intracellular signaling chain" EXACT [GOC:TermGenie] synonym: "positive regulation of intracellular signaling pathway" RELATED [GOC:TermGenie] synonym: "positive regulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "positive regulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie] synonym: "up regulation of intracellular signal transduction" EXACT [GOC:TermGenie] synonym: "up regulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie] synonym: "up regulation of intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "up regulation of intracellular signaling chain" EXACT [GOC:TermGenie] synonym: "up regulation of intracellular signaling pathway" RELATED [GOC:TermGenie] synonym: "up regulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "up regulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie] synonym: "up-regulation of intracellular signal transduction" EXACT [GOC:TermGenie] synonym: "up-regulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie] synonym: "up-regulation of intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "up-regulation of intracellular signaling chain" EXACT [GOC:TermGenie] synonym: "up-regulation of intracellular signaling pathway" RELATED [GOC:TermGenie] synonym: "up-regulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "up-regulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie] synonym: "upregulation of intracellular signal transduction" EXACT [GOC:TermGenie] synonym: "upregulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie] synonym: "upregulation of intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "upregulation of intracellular signaling chain" EXACT [GOC:TermGenie] synonym: "upregulation of intracellular signaling pathway" RELATED [GOC:TermGenie] synonym: "upregulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "upregulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie] is_a: GO:0009967 ! positive regulation of signal transduction is_a: GO:1902531 ! regulation of intracellular signal transduction intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0035556 ! intracellular signal transduction relationship: positively_regulates GO:0035556 ! intracellular signal transduction created_by: bf creation_date: 2013-12-02T11:33:10Z [Term] id: GO:1902570 name: protein localization to nucleolus namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within a nucleolus." [GOC:TermGenie, PMID:22809626] synonym: "protein localisation in nucleolus" EXACT [GOC:TermGenie] synonym: "protein localisation to nucleolus" EXACT [GOC:TermGenie] synonym: "protein localization in nucleolus" EXACT [GOC:TermGenie] is_a: GO:0034504 ! protein localization to nucleus intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0005730 ! nucleolus relationship: has_target_end_location GO:0005730 ! nucleolus created_by: mah creation_date: 2013-12-10T16:25:28Z [Term] id: GO:1902679 name: negative regulation of RNA biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of RNA biosynthetic process." [GO:jl, GO_REF:0000058, GOC:TermGenie] synonym: "down regulation of RNA anabolism" EXACT [GOC:TermGenie] synonym: "down regulation of RNA biosynthesis" EXACT [GOC:TermGenie] synonym: "down regulation of RNA biosynthetic process" EXACT [GOC:TermGenie] synonym: "down regulation of RNA formation" EXACT [GOC:TermGenie] synonym: "down regulation of RNA synthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA anabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA biosynthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA biosynthetic process" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA formation" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA synthesis" EXACT [GOC:TermGenie] synonym: "downregulation of RNA anabolism" EXACT [GOC:TermGenie] synonym: "downregulation of RNA biosynthesis" EXACT [GOC:TermGenie] synonym: "downregulation of RNA biosynthetic process" EXACT [GOC:TermGenie] synonym: "downregulation of RNA formation" EXACT [GOC:TermGenie] synonym: "downregulation of RNA synthesis" EXACT [GOC:TermGenie] synonym: "inhibition of RNA anabolism" NARROW [GOC:TermGenie] synonym: "inhibition of RNA biosynthesis" NARROW [GOC:TermGenie] synonym: "inhibition of RNA biosynthetic process" NARROW [GOC:TermGenie] synonym: "inhibition of RNA formation" NARROW [GOC:TermGenie] synonym: "inhibition of RNA synthesis" NARROW [GOC:TermGenie] synonym: "negative regulation of RNA anabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of RNA biosynthesis" EXACT [GOC:TermGenie] synonym: "negative regulation of RNA formation" EXACT [GOC:TermGenie] synonym: "negative regulation of RNA synthesis" EXACT [GOC:TermGenie] is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process is_a: GO:0051253 ! negative regulation of RNA metabolic process is_a: GO:2001141 ! regulation of RNA biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0032774 ! RNA biosynthetic process relationship: negatively_regulates GO:0032774 ! RNA biosynthetic process created_by: jl creation_date: 2014-02-05T16:32:01Z [Term] id: GO:1902680 name: positive regulation of RNA biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of RNA biosynthetic process." [GO:jl, GO_REF:0000058, GOC:TermGenie] synonym: "activation of RNA anabolism" NARROW [GOC:TermGenie] synonym: "activation of RNA biosynthesis" NARROW [GOC:TermGenie] synonym: "activation of RNA biosynthetic process" NARROW [GOC:TermGenie] synonym: "activation of RNA formation" NARROW [GOC:TermGenie] synonym: "activation of RNA synthesis" NARROW [GOC:TermGenie] synonym: "positive regulation of RNA anabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of RNA biosynthesis" EXACT [GOC:TermGenie] synonym: "positive regulation of RNA formation" EXACT [GOC:TermGenie] synonym: "positive regulation of RNA synthesis" EXACT [GOC:TermGenie] synonym: "up regulation of RNA anabolism" EXACT [GOC:TermGenie] synonym: "up regulation of RNA biosynthesis" EXACT [GOC:TermGenie] synonym: "up regulation of RNA biosynthetic process" EXACT [GOC:TermGenie] synonym: "up regulation of RNA formation" EXACT [GOC:TermGenie] synonym: "up regulation of RNA synthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of RNA anabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of RNA biosynthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of RNA biosynthetic process" EXACT [GOC:TermGenie] synonym: "up-regulation of RNA formation" EXACT [GOC:TermGenie] synonym: "up-regulation of RNA synthesis" EXACT [GOC:TermGenie] synonym: "upregulation of RNA anabolism" EXACT [GOC:TermGenie] synonym: "upregulation of RNA biosynthesis" EXACT [GOC:TermGenie] synonym: "upregulation of RNA biosynthetic process" EXACT [GOC:TermGenie] synonym: "upregulation of RNA formation" EXACT [GOC:TermGenie] synonym: "upregulation of RNA synthesis" EXACT [GOC:TermGenie] is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process is_a: GO:0051254 ! positive regulation of RNA metabolic process is_a: GO:2001141 ! regulation of RNA biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0032774 ! RNA biosynthetic process relationship: positively_regulates GO:0032774 ! RNA biosynthetic process created_by: jl creation_date: 2014-02-05T16:32:10Z [Term] id: GO:1902692 name: regulation of neuroblast proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of neuroblast proliferation." [GO_REF:0000058, GOC:PARL, GOC:rl, GOC:TermGenie, PMID:21168496] is_a: GO:2000177 ! regulation of neural precursor cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007405 ! neuroblast proliferation relationship: regulates GO:0007405 ! neuroblast proliferation created_by: rl creation_date: 2014-02-18T10:03:31Z [Term] id: GO:1902738 name: regulation of chondrocyte differentiation involved in endochondral bone morphogenesis namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage." [GO_REF:0000058, GOC:TermGenie, PMID:8662546] is_a: GO:0032330 ! regulation of chondrocyte differentiation is_a: GO:1903010 ! regulation of bone development is_a: GO:2000027 ! regulation of animal organ morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003413 ! chondrocyte differentiation involved in endochondral bone morphogenesis relationship: regulates GO:0003413 ! chondrocyte differentiation involved in endochondral bone morphogenesis created_by: mr creation_date: 2014-02-26T15:36:15Z [Term] id: GO:1902742 name: apoptotic process involved in development namespace: biological_process def: "Any apoptotic process that is involved in anatomical structure development." [GO_REF:0000060, GOC:mtg_apoptosis, GOC:pg, GOC:TermGenie] synonym: "activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "apoptotic process involved in anatomical structure development" EXACT [] synonym: "apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: part_of GO:0048856 ! anatomical structure development relationship: part_of GO:0048856 ! anatomical structure development created_by: pr creation_date: 2014-02-28T13:09:43Z [Term] id: GO:1902761 name: positive regulation of chondrocyte development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of chondrocyte development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16575901] synonym: "activation of chondrocyte development" NARROW [GOC:TermGenie] synonym: "up regulation of chondrocyte development" EXACT [GOC:TermGenie] synonym: "up-regulation of chondrocyte development" EXACT [GOC:TermGenie] synonym: "upregulation of chondrocyte development" EXACT [GOC:TermGenie] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0032332 ! positive regulation of chondrocyte differentiation is_a: GO:0061181 ! regulation of chondrocyte development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002063 ! chondrocyte development relationship: positively_regulates GO:0002063 ! chondrocyte development created_by: mr creation_date: 2014-03-07T17:45:55Z [Term] id: GO:1902809 name: regulation of skeletal muscle fiber differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of skeletal muscle fiber differentiation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:17879321] is_a: GO:0010830 ! regulation of myotube differentiation is_a: GO:2001014 ! regulation of skeletal muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0098528 ! skeletal muscle fiber differentiation relationship: regulates GO:0098528 ! skeletal muscle fiber differentiation created_by: mr creation_date: 2014-03-26T21:18:26Z [Term] id: GO:1902810 name: negative regulation of skeletal muscle fiber differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle fiber differentiation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:17879321] synonym: "down regulation of skeletal muscle fiber differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of skeletal muscle fiber differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of skeletal muscle fiber differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of skeletal muscle fiber differentiation" NARROW [GOC:TermGenie] is_a: GO:0010832 ! negative regulation of myotube differentiation is_a: GO:1902809 ! regulation of skeletal muscle fiber differentiation is_a: GO:2001015 ! negative regulation of skeletal muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0098528 ! skeletal muscle fiber differentiation relationship: negatively_regulates GO:0098528 ! skeletal muscle fiber differentiation created_by: mr creation_date: 2014-03-26T21:18:32Z [Term] id: GO:1902811 name: positive regulation of skeletal muscle fiber differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of skeletal muscle fiber differentiation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:17879321] synonym: "activation of skeletal muscle fiber differentiation" NARROW [GOC:TermGenie] synonym: "up regulation of skeletal muscle fiber differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of skeletal muscle fiber differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of skeletal muscle fiber differentiation" EXACT [GOC:TermGenie] is_a: GO:0010831 ! positive regulation of myotube differentiation is_a: GO:1902809 ! regulation of skeletal muscle fiber differentiation is_a: GO:2001016 ! positive regulation of skeletal muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0098528 ! skeletal muscle fiber differentiation relationship: positively_regulates GO:0098528 ! skeletal muscle fiber differentiation created_by: mr creation_date: 2014-03-26T21:18:38Z [Term] id: GO:1902816 name: regulation of protein localization to microtubule namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein localization to microtubule." [GO_REF:0000058, GOC:TermGenie, GOC:vw, PMID:23087209] synonym: "regulation of protein localisation to microtubule" EXACT [GOC:TermGenie] is_a: GO:0032880 ! regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0035372 ! protein localization to microtubule relationship: regulates GO:0035372 ! protein localization to microtubule created_by: tb creation_date: 2014-03-27T22:07:12Z [Term] id: GO:1902817 name: negative regulation of protein localization to microtubule namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to microtubule." [GO_REF:0000058, GOC:TermGenie, GOC:vw, PMID:23087209] synonym: "down regulation of protein localisation to microtubule" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization to microtubule" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation to microtubule" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to microtubule" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation to microtubule" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to microtubule" EXACT [GOC:TermGenie] synonym: "inhibition of protein localisation to microtubule" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization to microtubule" NARROW [GOC:TermGenie] synonym: "negative regulation of protein localisation to microtubule" EXACT [GOC:TermGenie] is_a: GO:1902816 ! regulation of protein localization to microtubule is_a: GO:1903828 ! negative regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0035372 ! protein localization to microtubule relationship: negatively_regulates GO:0035372 ! protein localization to microtubule created_by: tb creation_date: 2014-03-27T22:07:18Z [Term] id: GO:1902838 name: regulation of nuclear migration along microtubule namespace: biological_process def: "Any process that modulates the frequency, rate or extent of nuclear migration along microtubule." [GO_REF:0000058, GOC:TermGenie, PMID:23087209] synonym: "regulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "regulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "regulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "regulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "regulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] synonym: "regulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "regulation of nuclear movement, microtubule-mediated" BROAD [GOC:TermGenie] synonym: "regulation of nucleus migration" BROAD [GOC:TermGenie] synonym: "regulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] synonym: "regulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] is_a: GO:1902513 ! regulation of organelle transport along microtubule intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030473 ! nuclear migration along microtubule relationship: regulates GO:0030473 ! nuclear migration along microtubule created_by: vw creation_date: 2014-04-01T13:50:23Z [Term] id: GO:1902839 name: negative regulation of nuclear migration along microtubule namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of nuclear migration along microtubule." [GO_REF:0000058, GOC:TermGenie, PMID:23087209] synonym: "down regulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "down regulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "down regulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "down regulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "down regulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] synonym: "down regulation of nuclear migration along microtubule" EXACT [GOC:TermGenie] synonym: "down regulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "down regulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] synonym: "down regulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "down-regulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "down-regulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "down-regulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "down-regulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "down-regulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] synonym: "down-regulation of nuclear migration along microtubule" EXACT [GOC:TermGenie] synonym: "down-regulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "down-regulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] synonym: "down-regulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "downregulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "downregulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "downregulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "downregulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "downregulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] synonym: "downregulation of nuclear migration along microtubule" EXACT [GOC:TermGenie] synonym: "downregulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "downregulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] synonym: "downregulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "inhibition of microtubule cytoskeleton-dependent nuclear positioning" NARROW [GOC:TermGenie] synonym: "inhibition of microtubule cytoskeleton-dependent nucleus positioning" NARROW [GOC:TermGenie] synonym: "inhibition of microtubule-dependent nuclear positioning" NARROW [GOC:TermGenie] synonym: "inhibition of microtubule-dependent nucleus positioning" NARROW [GOC:TermGenie] synonym: "inhibition of microtubule-mediated nuclear migration" NARROW [GOC:TermGenie] synonym: "inhibition of nuclear migration along microtubule" NARROW [GOC:TermGenie] synonym: "inhibition of nuclear migration, microtubule-mediated" NARROW [GOC:TermGenie] synonym: "inhibition of transport of nucleus by microtubules" NARROW [GOC:TermGenie] synonym: "inhibition of transport of nucleus, microtubule-mediated" NARROW [GOC:TermGenie] synonym: "negative regulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "negative regulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "negative regulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "negative regulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "negative regulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] synonym: "negative regulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "negative regulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] synonym: "negative regulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] is_a: GO:0032387 ! negative regulation of intracellular transport is_a: GO:1902838 ! regulation of nuclear migration along microtubule intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030473 ! nuclear migration along microtubule relationship: negatively_regulates GO:0030473 ! nuclear migration along microtubule created_by: vw creation_date: 2014-04-01T13:50:29Z [Term] id: GO:1902840 name: positive regulation of nuclear migration along microtubule namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of nuclear migration along microtubule." [GO_REF:0000058, GOC:TermGenie, PMID:23087209] synonym: "activation of microtubule cytoskeleton-dependent nuclear positioning" NARROW [GOC:TermGenie] synonym: "activation of microtubule cytoskeleton-dependent nucleus positioning" NARROW [GOC:TermGenie] synonym: "activation of microtubule-dependent nuclear positioning" NARROW [GOC:TermGenie] synonym: "activation of microtubule-dependent nucleus positioning" NARROW [GOC:TermGenie] synonym: "activation of microtubule-mediated nuclear migration" NARROW [GOC:TermGenie] synonym: "activation of nuclear migration along microtubule" NARROW [GOC:TermGenie] synonym: "activation of nuclear migration, microtubule-mediated" NARROW [GOC:TermGenie] synonym: "activation of transport of nucleus by microtubules" NARROW [GOC:TermGenie] synonym: "activation of transport of nucleus, microtubule-mediated" NARROW [GOC:TermGenie] synonym: "positive regulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "positive regulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "positive regulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "positive regulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "positive regulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] synonym: "positive regulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "positive regulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] synonym: "positive regulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "up regulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "up regulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "up regulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "up regulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "up regulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] synonym: "up regulation of nuclear migration along microtubule" EXACT [GOC:TermGenie] synonym: "up regulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "up regulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] synonym: "up regulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "up-regulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "up-regulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "up-regulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "up-regulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "up-regulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] synonym: "up-regulation of nuclear migration along microtubule" EXACT [GOC:TermGenie] synonym: "up-regulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "up-regulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] synonym: "up-regulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "upregulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "upregulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "upregulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "upregulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "upregulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] synonym: "upregulation of nuclear migration along microtubule" EXACT [GOC:TermGenie] synonym: "upregulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "upregulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] synonym: "upregulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] is_a: GO:0032388 ! positive regulation of intracellular transport is_a: GO:1902838 ! regulation of nuclear migration along microtubule intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030473 ! nuclear migration along microtubule relationship: positively_regulates GO:0030473 ! nuclear migration along microtubule created_by: vw creation_date: 2014-04-01T13:50:35Z [Term] id: GO:1902850 name: microtubule cytoskeleton organization involved in mitosis namespace: biological_process def: "Any microtubule cytoskeleton organization that is involved in mitosis." [GO_REF:0000060, GOC:TermGenie, PMID:18799626] synonym: "microtubule cytoskeleton organisation involved in mitosis" EXACT [GOC:TermGenie] synonym: "microtubule cytoskeleton organization and biogenesis involved in mitosis" RELATED [GOC:TermGenie] synonym: "microtubule dynamics involved in mitosis" EXACT [GOC:TermGenie] is_a: GO:0000226 ! microtubule cytoskeleton organization is_a: GO:1903047 ! mitotic cell cycle process intersection_of: GO:0000226 ! microtubule cytoskeleton organization intersection_of: part_of GO:0000278 ! mitotic cell cycle created_by: vw creation_date: 2014-04-02T14:19:38Z [Term] id: GO:1902863 name: regulation of embryonic camera-type eye development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of embryonic camera-type eye development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] synonym: "regulation of embryonic eye development" EXACT [GOC:TermGenie] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0031076 ! embryonic camera-type eye development relationship: regulates GO:0031076 ! embryonic camera-type eye development created_by: mr creation_date: 2014-04-03T15:24:00Z [Term] id: GO:1902864 name: negative regulation of embryonic camera-type eye development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of embryonic camera-type eye development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] synonym: "down regulation of embryonic camera-type eye development" EXACT [GOC:TermGenie] synonym: "down regulation of embryonic eye development" EXACT [GOC:TermGenie] synonym: "down-regulation of embryonic camera-type eye development" EXACT [GOC:TermGenie] synonym: "down-regulation of embryonic eye development" EXACT [GOC:TermGenie] synonym: "downregulation of embryonic camera-type eye development" EXACT [GOC:TermGenie] synonym: "downregulation of embryonic eye development" EXACT [GOC:TermGenie] synonym: "inhibition of embryonic camera-type eye development" NARROW [GOC:TermGenie] synonym: "inhibition of embryonic eye development" NARROW [GOC:TermGenie] synonym: "negative regulation of embryonic eye development" EXACT [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:1902863 ! regulation of embryonic camera-type eye development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0031076 ! embryonic camera-type eye development relationship: negatively_regulates GO:0031076 ! embryonic camera-type eye development created_by: mr creation_date: 2014-04-03T15:24:06Z [Term] id: GO:1902865 name: positive regulation of embryonic camera-type eye development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of embryonic camera-type eye development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] synonym: "activation of embryonic camera-type eye development" NARROW [GOC:TermGenie] synonym: "activation of embryonic eye development" NARROW [GOC:TermGenie] synonym: "positive regulation of embryonic eye development" EXACT [GOC:TermGenie] synonym: "up regulation of embryonic camera-type eye development" EXACT [GOC:TermGenie] synonym: "up regulation of embryonic eye development" EXACT [GOC:TermGenie] synonym: "up-regulation of embryonic camera-type eye development" EXACT [GOC:TermGenie] synonym: "up-regulation of embryonic eye development" EXACT [GOC:TermGenie] synonym: "upregulation of embryonic camera-type eye development" EXACT [GOC:TermGenie] synonym: "upregulation of embryonic eye development" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:1902863 ! regulation of embryonic camera-type eye development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0031076 ! embryonic camera-type eye development relationship: positively_regulates GO:0031076 ! embryonic camera-type eye development created_by: mr creation_date: 2014-04-03T15:24:12Z [Term] id: GO:1902866 name: regulation of retina development in camera-type eye namespace: biological_process def: "Any process that modulates the frequency, rate or extent of retina development in camera-type eye." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] synonym: "regulation of retina development in camera-style eye" EXACT [GOC:TermGenie] synonym: "regulation of retinal development" RELATED [GOC:TermGenie] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060041 ! retina development in camera-type eye relationship: regulates GO:0060041 ! retina development in camera-type eye created_by: mr creation_date: 2014-04-03T15:24:17Z [Term] id: GO:1902867 name: negative regulation of retina development in camera-type eye namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of retina development in camera-type eye." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] synonym: "down regulation of retina development in camera-style eye" EXACT [GOC:TermGenie] synonym: "down regulation of retina development in camera-type eye" EXACT [GOC:TermGenie] synonym: "down regulation of retinal development" RELATED [GOC:TermGenie] synonym: "down-regulation of retina development in camera-style eye" EXACT [GOC:TermGenie] synonym: "down-regulation of retina development in camera-type eye" EXACT [GOC:TermGenie] synonym: "down-regulation of retinal development" RELATED [GOC:TermGenie] synonym: "downregulation of retina development in camera-style eye" EXACT [GOC:TermGenie] synonym: "downregulation of retina development in camera-type eye" EXACT [GOC:TermGenie] synonym: "downregulation of retinal development" RELATED [GOC:TermGenie] synonym: "inhibition of retina development in camera-style eye" NARROW [GOC:TermGenie] synonym: "inhibition of retina development in camera-type eye" NARROW [GOC:TermGenie] synonym: "inhibition of retinal development" RELATED [GOC:TermGenie] synonym: "negative regulation of retina development in camera-style eye" EXACT [GOC:TermGenie] synonym: "negative regulation of retinal development" RELATED [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1902866 ! regulation of retina development in camera-type eye intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060041 ! retina development in camera-type eye relationship: negatively_regulates GO:0060041 ! retina development in camera-type eye created_by: mr creation_date: 2014-04-03T15:24:23Z [Term] id: GO:1902868 name: positive regulation of retina development in camera-type eye namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of retina development in camera-type eye." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] synonym: "activation of retina development in camera-style eye" NARROW [GOC:TermGenie] synonym: "activation of retina development in camera-type eye" NARROW [GOC:TermGenie] synonym: "activation of retinal development" RELATED [GOC:TermGenie] synonym: "positive regulation of retina development in camera-style eye" EXACT [GOC:TermGenie] synonym: "positive regulation of retinal development" RELATED [GOC:TermGenie] synonym: "up regulation of retina development in camera-style eye" EXACT [GOC:TermGenie] synonym: "up regulation of retina development in camera-type eye" EXACT [GOC:TermGenie] synonym: "up regulation of retinal development" RELATED [GOC:TermGenie] synonym: "up-regulation of retina development in camera-style eye" EXACT [GOC:TermGenie] synonym: "up-regulation of retina development in camera-type eye" EXACT [GOC:TermGenie] synonym: "up-regulation of retinal development" RELATED [GOC:TermGenie] synonym: "upregulation of retina development in camera-style eye" EXACT [GOC:TermGenie] synonym: "upregulation of retina development in camera-type eye" EXACT [GOC:TermGenie] synonym: "upregulation of retinal development" RELATED [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1902866 ! regulation of retina development in camera-type eye intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060041 ! retina development in camera-type eye relationship: positively_regulates GO:0060041 ! retina development in camera-type eye created_by: mr creation_date: 2014-04-03T15:24:29Z [Term] id: GO:1902875 name: regulation of embryonic pattern specification namespace: biological_process def: "Any process that modulates the frequency, rate or extent of embryonic pattern specification." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] synonym: "regulation of embryonic pattern biosynthesis" BROAD [GOC:TermGenie] synonym: "regulation of embryonic pattern formation" BROAD [GOC:TermGenie] synonym: "regulation of ventral/lateral system" RELATED [GOC:TermGenie] is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0009880 ! embryonic pattern specification relationship: regulates GO:0009880 ! embryonic pattern specification created_by: mr creation_date: 2014-04-03T15:25:15Z [Term] id: GO:1902876 name: negative regulation of embryonic pattern specification namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of embryonic pattern specification." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] synonym: "down regulation of embryonic pattern specification" EXACT [GOC:TermGenie] synonym: "down regulation of ventral/lateral system" RELATED [GOC:TermGenie] synonym: "down-regulation of embryonic pattern specification" EXACT [GOC:TermGenie] synonym: "down-regulation of ventral/lateral system" RELATED [GOC:TermGenie] synonym: "downregulation of embryonic pattern specification" EXACT [GOC:TermGenie] synonym: "downregulation of ventral/lateral system" RELATED [GOC:TermGenie] synonym: "inhibition of embryonic pattern specification" NARROW [GOC:TermGenie] synonym: "inhibition of ventral/lateral system" RELATED [GOC:TermGenie] synonym: "negative regulation of ventral/lateral system" RELATED [GOC:TermGenie] is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1902875 ! regulation of embryonic pattern specification intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0009880 ! embryonic pattern specification relationship: negatively_regulates GO:0009880 ! embryonic pattern specification created_by: mr creation_date: 2014-04-03T15:25:20Z [Term] id: GO:1902877 name: positive regulation of embryonic pattern specification namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of embryonic pattern specification." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] synonym: "activation of embryonic pattern specification" NARROW [GOC:TermGenie] synonym: "activation of ventral/lateral system" RELATED [GOC:TermGenie] synonym: "positive regulation of ventral/lateral system" RELATED [GOC:TermGenie] synonym: "up regulation of embryonic pattern specification" EXACT [GOC:TermGenie] synonym: "up regulation of ventral/lateral system" RELATED [GOC:TermGenie] synonym: "up-regulation of embryonic pattern specification" EXACT [GOC:TermGenie] synonym: "up-regulation of ventral/lateral system" RELATED [GOC:TermGenie] synonym: "upregulation of embryonic pattern specification" EXACT [GOC:TermGenie] synonym: "upregulation of ventral/lateral system" RELATED [GOC:TermGenie] is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1902875 ! regulation of embryonic pattern specification intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0009880 ! embryonic pattern specification relationship: positively_regulates GO:0009880 ! embryonic pattern specification created_by: mr creation_date: 2014-04-03T15:25:26Z [Term] id: GO:1902903 name: regulation of supramolecular fiber organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of supramolecular fiber organization." [GO_REF:0000058, GOC:PARL, GOC:rl, GOC:TermGenie, PMID:23921388] comment: HSPA8, human, P11142 in PMID:23921388 inferred from direct assay to negatively regulate fibrillation of alpha-Syn in vitro synonym: "regulation of fibril organisation" RELATED [GOC:TermGenie] is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0097435 ! supramolecular fiber organization relationship: regulates GO:0097435 ! supramolecular fiber organization created_by: rl creation_date: 2014-04-15T16:46:36Z [Term] id: GO:1902904 name: negative regulation of supramolecular fiber organization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of fibril organization." [GO_REF:0000058, GOC:PARL, GOC:rl, GOC:TermGenie, PMID:23921388] comment: HSPA8, human, P11142 in PMID:23921388 inferred from direct assay to negatively regulate fibrillation of alpha-Syn in vitro synonym: "down regulation of fibril organisation" RELATED [GOC:TermGenie] synonym: "down regulation of fibril organization" RELATED [GOC:TermGenie] synonym: "down-regulation of fibril organisation" RELATED [GOC:TermGenie] synonym: "down-regulation of fibril organization" RELATED [GOC:TermGenie] synonym: "downregulation of fibril organisation" RELATED [GOC:TermGenie] synonym: "downregulation of fibril organization" RELATED [GOC:TermGenie] synonym: "inhibition of fibril organisation" NARROW [GOC:TermGenie] synonym: "inhibition of fibril organization" NARROW [GOC:TermGenie] synonym: "negative regulation of fibril organisation" RELATED [GOC:TermGenie] is_a: GO:0051129 ! negative regulation of cellular component organization is_a: GO:1902903 ! regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0097435 ! supramolecular fiber organization relationship: negatively_regulates GO:0097435 ! supramolecular fiber organization created_by: rl creation_date: 2014-04-15T16:46:42Z [Term] id: GO:1902905 name: positive regulation of supramolecular fiber organization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of supramolecular fiber organization." [GO_REF:0000058, GOC:PARL, GOC:rl, GOC:TermGenie, PMID:23921388] comment: HSPA8, human, P11142 in PMID:23921388 inferred from direct assay to negatively regulate fibrillation of alpha-Syn in vitro synonym: "activation of fibril organisation" NARROW [GOC:TermGenie] synonym: "activation of fibril organization" NARROW [GOC:TermGenie] synonym: "positive regulation of fibril organisation" RELATED [GOC:TermGenie] synonym: "up regulation of fibril organisation" RELATED [GOC:TermGenie] synonym: "up regulation of fibril organization" RELATED [GOC:TermGenie] synonym: "up-regulation of fibril organisation" RELATED [GOC:TermGenie] synonym: "up-regulation of fibril organization" RELATED [GOC:TermGenie] synonym: "upregulation of fibril organisation" RELATED [GOC:TermGenie] synonym: "upregulation of fibril organization" RELATED [GOC:TermGenie] is_a: GO:0051130 ! positive regulation of cellular component organization is_a: GO:1902903 ! regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0097435 ! supramolecular fiber organization relationship: positively_regulates GO:0097435 ! supramolecular fiber organization created_by: rl creation_date: 2014-04-15T16:46:48Z [Term] id: GO:1902913 name: positive regulation of neuroepithelial cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of neuroepithelial cell differentiation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16916506] synonym: "activation of neuroepithelial cell differentiation" NARROW [GOC:TermGenie] synonym: "up regulation of neuroepithelial cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of neuroepithelial cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of neuroepithelial cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0030858 ! positive regulation of epithelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060563 ! neuroepithelial cell differentiation relationship: positively_regulates GO:0060563 ! neuroepithelial cell differentiation created_by: mr creation_date: 2014-04-18T21:06:42Z [Term] id: GO:1903008 name: organelle disassembly namespace: biological_process def: "The disaggregation of an organelle into its constituent components." [GO_REF:0000079, GOC:TermGenie] synonym: "organelle degradation" EXACT [] is_a: GO:0006996 ! organelle organization is_a: GO:0022411 ! cellular component disassembly intersection_of: GO:0022411 ! cellular component disassembly intersection_of: results_in_disassembly_of GO:0043226 ! organelle relationship: results_in_disassembly_of GO:0043226 ! organelle created_by: jl creation_date: 2014-05-13T12:36:03Z [Term] id: GO:1903010 name: regulation of bone development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of bone development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:22510437] is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060348 ! bone development relationship: regulates GO:0060348 ! bone development created_by: mr creation_date: 2014-05-13T22:41:53Z [Term] id: GO:1903011 name: negative regulation of bone development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of bone development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:22510437] synonym: "down regulation of bone development" EXACT [GOC:TermGenie] synonym: "down-regulation of bone development" EXACT [GOC:TermGenie] synonym: "downregulation of bone development" EXACT [GOC:TermGenie] synonym: "inhibition of bone development" NARROW [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1903010 ! regulation of bone development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060348 ! bone development relationship: negatively_regulates GO:0060348 ! bone development created_by: mr creation_date: 2014-05-13T22:42:00Z [Term] id: GO:1903012 name: positive regulation of bone development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of bone development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:22510437] synonym: "activation of bone development" NARROW [GOC:TermGenie] synonym: "up regulation of bone development" EXACT [GOC:TermGenie] synonym: "up-regulation of bone development" EXACT [GOC:TermGenie] synonym: "upregulation of bone development" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1903010 ! regulation of bone development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060348 ! bone development relationship: positively_regulates GO:0060348 ! bone development created_by: mr creation_date: 2014-05-13T22:42:06Z [Term] id: GO:1903018 name: regulation of glycoprotein metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of glycoprotein metabolic process." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:23544079] comment: human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) and thus the metabolism of glycoproteins, demonstrated in Figure 4A PMID:23544079, (IDA), the negative regulation term would be applied to this protein synonym: "regulation of glycoprotein metabolism" EXACT [GOC:TermGenie] is_a: GO:0060255 ! regulation of macromolecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0009100 ! glycoprotein metabolic process relationship: regulates GO:0009100 ! glycoprotein metabolic process created_by: rl creation_date: 2014-05-14T18:44:19Z [Term] id: GO:1903019 name: negative regulation of glycoprotein metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of glycoprotein metabolic process." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:23544079] comment: human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) and thus the metabolism of glycoproteins, demonstrated in Figure 4A PMID:23544079, (IDA), the negative regulation term would be applied to this protein synonym: "down regulation of glycoprotein metabolic process" EXACT [GOC:TermGenie] synonym: "down regulation of glycoprotein metabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of glycoprotein metabolic process" EXACT [GOC:TermGenie] synonym: "down-regulation of glycoprotein metabolism" EXACT [GOC:TermGenie] synonym: "downregulation of glycoprotein metabolic process" EXACT [GOC:TermGenie] synonym: "downregulation of glycoprotein metabolism" EXACT [GOC:TermGenie] synonym: "inhibition of glycoprotein metabolic process" NARROW [GOC:TermGenie] synonym: "inhibition of glycoprotein metabolism" NARROW [GOC:TermGenie] synonym: "negative regulation of glycoprotein metabolism" EXACT [GOC:TermGenie] is_a: GO:0010605 ! negative regulation of macromolecule metabolic process is_a: GO:1903018 ! regulation of glycoprotein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0009100 ! glycoprotein metabolic process relationship: negatively_regulates GO:0009100 ! glycoprotein metabolic process created_by: rl creation_date: 2014-05-14T18:44:25Z [Term] id: GO:1903020 name: positive regulation of glycoprotein metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of glycoprotein metabolic process." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:23544079] comment: human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) and thus the metabolism of glycoproteins, demonstrated in Figure 4A PMID:23544079, (IDA), the negative regulation term would be applied to this protein synonym: "activation of glycoprotein metabolic process" NARROW [GOC:TermGenie] synonym: "activation of glycoprotein metabolism" NARROW [GOC:TermGenie] synonym: "positive regulation of glycoprotein metabolism" EXACT [GOC:TermGenie] synonym: "up regulation of glycoprotein metabolic process" EXACT [GOC:TermGenie] synonym: "up regulation of glycoprotein metabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of glycoprotein metabolic process" EXACT [GOC:TermGenie] synonym: "up-regulation of glycoprotein metabolism" EXACT [GOC:TermGenie] synonym: "upregulation of glycoprotein metabolic process" EXACT [GOC:TermGenie] synonym: "upregulation of glycoprotein metabolism" EXACT [GOC:TermGenie] is_a: GO:0010604 ! positive regulation of macromolecule metabolic process is_a: GO:1903018 ! regulation of glycoprotein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0009100 ! glycoprotein metabolic process relationship: positively_regulates GO:0009100 ! glycoprotein metabolic process created_by: rl creation_date: 2014-05-14T18:44:31Z [Term] id: GO:1903037 name: regulation of leukocyte cell-cell adhesion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of leukocyte cell-cell adhesion." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21106532] comment: Exogenous expression of ASS1 or NOS3 in HUVECs enhances NO production and inhibits monocyte adhesion synonym: "regulation of leukocyte adhesion" EXACT [GOC:TermGenie] synonym: "regulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] is_a: GO:0022407 ! regulation of cell-cell adhesion intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007159 ! leukocyte cell-cell adhesion relationship: regulates GO:0007159 ! leukocyte cell-cell adhesion created_by: rl creation_date: 2014-05-19T15:29:58Z [Term] id: GO:1903038 name: negative regulation of leukocyte cell-cell adhesion namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte cell-cell adhesion." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21106532] comment: Exogenous expression of ASS1 or NOS3 in HUVECs enhances NO production and inhibits monocyte adhesion synonym: "down regulation of leukocyte adhesion" EXACT [GOC:TermGenie] synonym: "down regulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] synonym: "down regulation of leukocyte cell-cell adhesion" EXACT [GOC:TermGenie] synonym: "down-regulation of leukocyte adhesion" EXACT [GOC:TermGenie] synonym: "down-regulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] synonym: "down-regulation of leukocyte cell-cell adhesion" EXACT [GOC:TermGenie] synonym: "downregulation of leukocyte adhesion" EXACT [GOC:TermGenie] synonym: "downregulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] synonym: "downregulation of leukocyte cell-cell adhesion" EXACT [GOC:TermGenie] synonym: "inhibition of leukocyte adhesion" NARROW [GOC:TermGenie] synonym: "inhibition of leukocyte cell adhesion" NARROW [GOC:TermGenie] synonym: "inhibition of leukocyte cell-cell adhesion" NARROW [GOC:TermGenie] synonym: "negative regulation of leukocyte adhesion" EXACT [GOC:TermGenie] synonym: "negative regulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] is_a: GO:0022408 ! negative regulation of cell-cell adhesion is_a: GO:1903037 ! regulation of leukocyte cell-cell adhesion intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007159 ! leukocyte cell-cell adhesion relationship: negatively_regulates GO:0007159 ! leukocyte cell-cell adhesion created_by: rl creation_date: 2014-05-19T15:30:05Z [Term] id: GO:1903039 name: positive regulation of leukocyte cell-cell adhesion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of leukocyte cell-cell adhesion." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21106532] comment: Exogenous expression of ASS1 or NOS3 in HUVECs enhances NO production and inhibits monocyte adhesion synonym: "activation of leukocyte adhesion" NARROW [GOC:TermGenie] synonym: "activation of leukocyte cell adhesion" NARROW [GOC:TermGenie] synonym: "activation of leukocyte cell-cell adhesion" NARROW [GOC:TermGenie] synonym: "positive regulation of leukocyte adhesion" EXACT [GOC:TermGenie] synonym: "positive regulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] synonym: "up regulation of leukocyte adhesion" EXACT [GOC:TermGenie] synonym: "up regulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] synonym: "up regulation of leukocyte cell-cell adhesion" EXACT [GOC:TermGenie] synonym: "up-regulation of leukocyte adhesion" EXACT [GOC:TermGenie] synonym: "up-regulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] synonym: "up-regulation of leukocyte cell-cell adhesion" EXACT [GOC:TermGenie] synonym: "upregulation of leukocyte adhesion" EXACT [GOC:TermGenie] synonym: "upregulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] synonym: "upregulation of leukocyte cell-cell adhesion" EXACT [GOC:TermGenie] is_a: GO:0022409 ! positive regulation of cell-cell adhesion is_a: GO:1903037 ! regulation of leukocyte cell-cell adhesion intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007159 ! leukocyte cell-cell adhesion relationship: positively_regulates GO:0007159 ! leukocyte cell-cell adhesion created_by: rl creation_date: 2014-05-19T15:30:15Z [Term] id: GO:1903045 name: neural crest cell migration involved in sympathetic nervous system development namespace: biological_process def: "Any neural crest cell migration that is involved in sympathetic nervous system development." [GO_REF:0000060, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:19325129] comment: Sema3a (O08665, mouse) is involved in neural crest cell migration involved in sympathetic nervous system development is_a: GO:1901166 ! neural crest cell migration involved in autonomic nervous system development intersection_of: GO:0001755 ! neural crest cell migration intersection_of: part_of GO:0048485 ! sympathetic nervous system development relationship: part_of GO:0048485 ! sympathetic nervous system development created_by: rl creation_date: 2014-05-22T07:06:02Z [Term] id: GO:1903046 name: meiotic cell cycle process namespace: biological_process def: "A process that is part of the meiotic cell cycle." [GO_REF:0000060, GOC:mtg_cell_cycle, GOC:TermGenie] subset: gocheck_do_not_annotate subset: goslim_pombe is_a: GO:0022402 ! cell cycle process is_a: GO:0022414 ! reproductive process intersection_of: GO:0009987 ! cellular process intersection_of: part_of GO:0051321 ! meiotic cell cycle disjoint_from: GO:1903047 ! mitotic cell cycle process relationship: part_of GO:0051321 ! meiotic cell cycle created_by: jl creation_date: 2014-05-22T14:22:28Z [Term] id: GO:1903047 name: mitotic cell cycle process namespace: biological_process def: "A process that is part of the mitotic cell cycle." [GO_REF:0000060, GOC:mtg_cell_cycle, GOC:TermGenie] subset: gocheck_do_not_annotate is_a: GO:0022402 ! cell cycle process intersection_of: GO:0009987 ! cellular process intersection_of: part_of GO:0000278 ! mitotic cell cycle relationship: part_of GO:0000278 ! mitotic cell cycle created_by: jl creation_date: 2014-05-22T14:22:34Z [Term] id: GO:1903053 name: regulation of extracellular matrix organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of extracellular matrix organization." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:22357537] synonym: "regulation of extracellular matrix organisation" EXACT [GOC:TermGenie] synonym: "regulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030198 ! extracellular matrix organization relationship: regulates GO:0030198 ! extracellular matrix organization created_by: rl creation_date: 2014-05-23T17:15:41Z [Term] id: GO:1903054 name: negative regulation of extracellular matrix organization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix organization." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:22357537] synonym: "down regulation of extracellular matrix organisation" EXACT [GOC:TermGenie] synonym: "down regulation of extracellular matrix organization" EXACT [GOC:TermGenie] synonym: "down regulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] synonym: "down-regulation of extracellular matrix organisation" EXACT [GOC:TermGenie] synonym: "down-regulation of extracellular matrix organization" EXACT [GOC:TermGenie] synonym: "down-regulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] synonym: "downregulation of extracellular matrix organisation" EXACT [GOC:TermGenie] synonym: "downregulation of extracellular matrix organization" EXACT [GOC:TermGenie] synonym: "downregulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] synonym: "inhibition of extracellular matrix organisation" NARROW [GOC:TermGenie] synonym: "inhibition of extracellular matrix organization" NARROW [GOC:TermGenie] synonym: "inhibition of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] synonym: "negative regulation of extracellular matrix organisation" EXACT [GOC:TermGenie] synonym: "negative regulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] is_a: GO:0051129 ! negative regulation of cellular component organization is_a: GO:1903053 ! regulation of extracellular matrix organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030198 ! extracellular matrix organization relationship: negatively_regulates GO:0030198 ! extracellular matrix organization created_by: rl creation_date: 2014-05-23T17:15:47Z [Term] id: GO:1903055 name: positive regulation of extracellular matrix organization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of extracellular matrix organization." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:22357537] synonym: "activation of extracellular matrix organisation" NARROW [GOC:TermGenie] synonym: "activation of extracellular matrix organization" NARROW [GOC:TermGenie] synonym: "activation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] synonym: "positive regulation of extracellular matrix organisation" EXACT [GOC:TermGenie] synonym: "positive regulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] synonym: "up regulation of extracellular matrix organisation" EXACT [GOC:TermGenie] synonym: "up regulation of extracellular matrix organization" EXACT [GOC:TermGenie] synonym: "up regulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] synonym: "up-regulation of extracellular matrix organisation" EXACT [GOC:TermGenie] synonym: "up-regulation of extracellular matrix organization" EXACT [GOC:TermGenie] synonym: "up-regulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] synonym: "upregulation of extracellular matrix organisation" EXACT [GOC:TermGenie] synonym: "upregulation of extracellular matrix organization" EXACT [GOC:TermGenie] synonym: "upregulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] is_a: GO:0051130 ! positive regulation of cellular component organization is_a: GO:1903053 ! regulation of extracellular matrix organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030198 ! extracellular matrix organization relationship: positively_regulates GO:0030198 ! extracellular matrix organization created_by: rl creation_date: 2014-05-23T17:15:53Z [Term] id: GO:1903076 name: regulation of protein localization to plasma membrane namespace: biological_process alt_id: GO:0090003 alt_id: GO:1905963 def: "Any process that modulates the frequency, rate or extent of protein localization to plasma membrane." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:11602640] synonym: "regulation of establishment of protein localisation in plasma membrane" RELATED [GOC:mah] synonym: "regulation of establishment of protein localization in plasma membrane" RELATED [] synonym: "regulation of establishment of protein localization to plasma membrane" RELATED [] synonym: "regulation of protein localisation in plasma membrane" RELATED [GOC:TermGenie] synonym: "regulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] synonym: "regulation of protein targeting to plasma membrane" RELATED [] synonym: "regulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie] is_a: GO:1904375 ! regulation of protein localization to cell periphery is_a: GO:1905475 ! regulation of protein localization to membrane intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0072659 ! protein localization to plasma membrane relationship: regulates GO:0072659 ! protein localization to plasma membrane created_by: tb creation_date: 2009-07-10T10:32:44Z [Term] id: GO:1903077 name: negative regulation of protein localization to plasma membrane namespace: biological_process alt_id: GO:0090005 alt_id: GO:1905964 def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to plasma membrane." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:11602640] synonym: "down regulation of protein localisation in plasma membrane" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization to plasma membrane" EXACT [GOC:TermGenie] synonym: "down regulation of protein targeting to plasma membrane" RELATED [GOC:TermGenie] synonym: "down regulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie] synonym: "down-regulation of protein localisation in plasma membrane" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to plasma membrane" EXACT [GOC:TermGenie] synonym: "down-regulation of protein targeting to plasma membrane" RELATED [GOC:TermGenie] synonym: "down-regulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie] synonym: "downregulation of protein localisation in plasma membrane" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to plasma membrane" EXACT [GOC:TermGenie] synonym: "downregulation of protein targeting to plasma membrane" RELATED [GOC:TermGenie] synonym: "downregulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie] synonym: "inhibition of protein localisation in plasma membrane" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization in plasma membrane" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization to plasma membrane" NARROW [GOC:TermGenie] synonym: "inhibition of protein targeting to plasma membrane" NARROW [GOC:TermGenie] synonym: "inhibition of protein-plasma membrane targeting" NARROW [GOC:TermGenie] synonym: "negative regulation of establishment of protein localisation in plasma membrane" RELATED [GOC:mah] synonym: "negative regulation of establishment of protein localization in plasma membrane" RELATED [] synonym: "negative regulation of establishment of protein localization to plasma membrane" RELATED [] synonym: "negative regulation of protein localisation in plasma membrane" RELATED [GOC:TermGenie] synonym: "negative regulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] synonym: "negative regulation of protein targeting to plasma membrane" RELATED [] synonym: "negative regulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie] is_a: GO:1903076 ! regulation of protein localization to plasma membrane is_a: GO:1904376 ! negative regulation of protein localization to cell periphery is_a: GO:1905476 ! negative regulation of protein localization to membrane intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0072659 ! protein localization to plasma membrane relationship: negatively_regulates GO:0072659 ! protein localization to plasma membrane created_by: tb creation_date: 2014-05-29T17:10:16Z [Term] id: GO:1903078 name: positive regulation of protein localization to plasma membrane namespace: biological_process alt_id: GO:0090004 alt_id: GO:1905965 def: "Any process that activates or increases the frequency, rate or extent of protein localization to plasma membrane." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:11602640] synonym: "activation of protein localisation in plasma membrane" NARROW [GOC:TermGenie] synonym: "activation of protein localization in plasma membrane" NARROW [GOC:TermGenie] synonym: "activation of protein localization to plasma membrane" NARROW [GOC:TermGenie] synonym: "activation of protein targeting to plasma membrane" NARROW [GOC:TermGenie] synonym: "activation of protein-plasma membrane targeting" NARROW [GOC:TermGenie] synonym: "positive regulation of establishment of protein localisation in plasma membrane" RELATED [GOC:mah] synonym: "positive regulation of establishment of protein localization to plasma membrane" RELATED [] synonym: "positive regulation of protein localisation in plasma membrane" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] synonym: "positive regulation of protein targeting to plasma membrane" RELATED [] synonym: "positive regulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie] synonym: "up regulation of protein localisation in plasma membrane" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization to plasma membrane" EXACT [GOC:TermGenie] synonym: "up regulation of protein targeting to plasma membrane" RELATED [GOC:TermGenie] synonym: "up regulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie] synonym: "up-regulation of protein localisation in plasma membrane" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to plasma membrane" EXACT [GOC:TermGenie] synonym: "up-regulation of protein targeting to plasma membrane" RELATED [GOC:TermGenie] synonym: "up-regulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie] synonym: "upregulation of protein localisation in plasma membrane" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to plasma membrane" EXACT [GOC:TermGenie] synonym: "upregulation of protein targeting to plasma membrane" RELATED [GOC:TermGenie] synonym: "upregulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie] is_a: GO:1903076 ! regulation of protein localization to plasma membrane is_a: GO:1904377 ! positive regulation of protein localization to cell periphery is_a: GO:1905477 ! positive regulation of protein localization to membrane intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0072659 ! protein localization to plasma membrane relationship: positively_regulates GO:0072659 ! protein localization to plasma membrane created_by: tb creation_date: 2009-07-10T10:34:17Z [Term] id: GO:1903115 name: regulation of actin filament-based movement namespace: biological_process def: "Any process that modulates the frequency, rate or extent of actin filament-based movement." [GO_REF:0000058, GOC:TermGenie, PMID:24798735] is_a: GO:0032970 ! regulation of actin filament-based process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030048 ! actin filament-based movement relationship: regulates GO:0030048 ! actin filament-based movement created_by: al creation_date: 2014-06-12T16:55:57Z [Term] id: GO:1903116 name: positive regulation of actin filament-based movement namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of actin filament-based movement." [GO_REF:0000058, GOC:TermGenie, PMID:24798735] synonym: "activation of actin filament-based movement" NARROW [GOC:TermGenie] synonym: "up regulation of actin filament-based movement" EXACT [GOC:TermGenie] synonym: "up-regulation of actin filament-based movement" EXACT [GOC:TermGenie] synonym: "upregulation of actin filament-based movement" EXACT [GOC:TermGenie] is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:1903115 ! regulation of actin filament-based movement intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030048 ! actin filament-based movement relationship: positively_regulates GO:0030048 ! actin filament-based movement created_by: al creation_date: 2014-06-12T16:56:04Z [Term] id: GO:1903119 name: protein localization to actin cytoskeleton namespace: biological_process def: "A process in which a protein is transported to, or maintained in, the location of an actin cytoskeleton." [GO_REF:0000087, GOC:TermGenie, PMID:24798735] synonym: "protein localisation in actin cytoskeleton" EXACT [GOC:TermGenie] synonym: "protein localisation to actin cytoskeleton" EXACT [GOC:TermGenie] synonym: "protein localization in actin cytoskeleton" EXACT [GOC:TermGenie] is_a: GO:0044380 ! protein localization to cytoskeleton intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0015629 ! actin cytoskeleton relationship: has_target_end_location GO:0015629 ! actin cytoskeleton created_by: mah creation_date: 2014-06-16T11:27:09Z [Term] id: GO:1903120 name: protein localization to actin filament bundle namespace: biological_process def: "A process in which a protein is transported to, or maintained in, the location of an actin filament bundle." [GO_REF:0000087, GOC:TermGenie, PMID:24798735] synonym: "protein localisation in actin filament bundle" EXACT [GOC:TermGenie] synonym: "protein localisation to actin filament bundle" EXACT [GOC:TermGenie] synonym: "protein localization in actin filament bundle" EXACT [GOC:TermGenie] synonym: "protein localization to actin cable" RELATED [GOC:mah] is_a: GO:1903119 ! protein localization to actin cytoskeleton intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0032432 ! actin filament bundle relationship: has_target_end_location GO:0032432 ! actin filament bundle created_by: mah creation_date: 2014-06-16T11:27:16Z [Term] id: GO:1903131 name: mononuclear cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized features of a mononuclear cell." [CL:0000842, GO_REF:0000086, GOC:TermGenie, PMID:24759906] is_a: GO:0002521 ! leukocyte differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000842 ! mononuclear cell relationship: results_in_acquisition_of_features_of CL:0000842 ! mononuclear cell created_by: cls creation_date: 2014-06-25T15:47:09Z [Term] id: GO:1903224 name: regulation of endodermal cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of endodermal cell differentiation." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23154389] synonym: "regulation of endoderm cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0035987 ! endodermal cell differentiation relationship: regulates GO:0035987 ! endodermal cell differentiation created_by: als creation_date: 2014-07-29T13:22:35Z [Term] id: GO:1903225 name: negative regulation of endodermal cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of endodermal cell differentiation." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23154389] synonym: "down regulation of endoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of endodermal cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of endoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of endodermal cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of endoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of endodermal cell differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of endoderm cell differentiation" NARROW [GOC:TermGenie] synonym: "inhibition of endodermal cell differentiation" NARROW [GOC:TermGenie] synonym: "negative regulation of endoderm cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:1903224 ! regulation of endodermal cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0035987 ! endodermal cell differentiation relationship: negatively_regulates GO:0035987 ! endodermal cell differentiation created_by: als creation_date: 2014-07-29T13:22:41Z [Term] id: GO:1903226 name: positive regulation of endodermal cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of endodermal cell differentiation." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23154389] synonym: "activation of endoderm cell differentiation" NARROW [GOC:TermGenie] synonym: "activation of endodermal cell differentiation" NARROW [GOC:TermGenie] synonym: "positive regulation of endoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of endoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of endodermal cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of endoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of endodermal cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of endoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of endodermal cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:1903224 ! regulation of endodermal cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0035987 ! endodermal cell differentiation relationship: positively_regulates GO:0035987 ! endodermal cell differentiation created_by: als creation_date: 2014-07-29T13:22:47Z [Term] id: GO:1903292 name: protein localization to Golgi membrane namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within a Golgi membrane." [GO_REF:0000087, GOC:TermGenie, PMID:11378902] synonym: "protein localisation in Golgi membrane" EXACT [GOC:TermGenie] synonym: "protein localisation to Golgi membrane" EXACT [GOC:TermGenie] synonym: "protein localization in Golgi membrane" EXACT [GOC:TermGenie] is_a: GO:0034067 ! protein localization to Golgi apparatus is_a: GO:0072657 ! protein localization to membrane intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0000139 ! Golgi membrane relationship: has_target_end_location GO:0000139 ! Golgi membrane created_by: mah creation_date: 2014-08-12T14:22:31Z [Term] id: GO:1903335 name: regulation of vacuolar transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of vacuolar transport." [GO_REF:0000058, GOC:TermGenie, GOC:vw] is_a: GO:0032386 ! regulation of intracellular transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007034 ! vacuolar transport relationship: regulates GO:0007034 ! vacuolar transport created_by: vw creation_date: 2014-08-18T13:16:04Z [Term] id: GO:1903336 name: negative regulation of vacuolar transport namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of vacuolar transport." [GO_REF:0000058, GOC:TermGenie, GOC:vw] synonym: "down regulation of vacuolar transport" EXACT [GOC:TermGenie] synonym: "down-regulation of vacuolar transport" EXACT [GOC:TermGenie] synonym: "downregulation of vacuolar transport" EXACT [GOC:TermGenie] synonym: "inhibition of vacuolar transport" NARROW [GOC:TermGenie] is_a: GO:0032387 ! negative regulation of intracellular transport is_a: GO:1903335 ! regulation of vacuolar transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007034 ! vacuolar transport relationship: negatively_regulates GO:0007034 ! vacuolar transport created_by: vw creation_date: 2014-08-18T13:16:11Z [Term] id: GO:1903337 name: positive regulation of vacuolar transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of vacuolar transport." [GO_REF:0000058, GOC:TermGenie, GOC:vw] synonym: "activation of vacuolar transport" NARROW [GOC:TermGenie] synonym: "up regulation of vacuolar transport" EXACT [GOC:TermGenie] synonym: "up-regulation of vacuolar transport" EXACT [GOC:TermGenie] synonym: "upregulation of vacuolar transport" EXACT [GOC:TermGenie] is_a: GO:0032388 ! positive regulation of intracellular transport is_a: GO:1903335 ! regulation of vacuolar transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007034 ! vacuolar transport relationship: positively_regulates GO:0007034 ! vacuolar transport created_by: vw creation_date: 2014-08-18T13:16:19Z [Term] id: GO:1903353 name: regulation of nucleus organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of nucleus organization." [GO_REF:0000058, GOC:TermGenie, PMID:16943282] synonym: "regulation of nuclear morphology" RELATED [GOC:TermGenie] synonym: "regulation of nuclear organisation" EXACT [GOC:TermGenie] synonym: "regulation of nuclear organization" EXACT [GOC:TermGenie] synonym: "regulation of nuclear organization and biogenesis" RELATED [GOC:TermGenie] synonym: "regulation of nucleus organization and biogenesis" RELATED [GOC:TermGenie] is_a: GO:0033043 ! regulation of organelle organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006997 ! nucleus organization relationship: regulates GO:0006997 ! nucleus organization created_by: hjd creation_date: 2014-08-20T19:36:16Z [Term] id: GO:1903358 name: regulation of Golgi organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of Golgi organization." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:17562788] synonym: "regulation of Golgi organisation" EXACT [GOC:TermGenie] synonym: "regulation of Golgi organization and biogenesis" RELATED [GOC:TermGenie] is_a: GO:0033043 ! regulation of organelle organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007030 ! Golgi organization relationship: regulates GO:0007030 ! Golgi organization created_by: als creation_date: 2014-08-21T10:22:22Z [Term] id: GO:1903379 name: regulation of mitotic chromosome condensation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mitotic chromosome condensation." [GO_REF:0000058, GOC:TermGenie, PMID:9490640] is_a: GO:0010564 ! regulation of cell cycle process is_a: GO:0060623 ! regulation of chromosome condensation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007076 ! mitotic chromosome condensation relationship: regulates GO:0007076 ! mitotic chromosome condensation created_by: al creation_date: 2014-08-26T13:57:13Z [Term] id: GO:1903380 name: positive regulation of mitotic chromosome condensation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mitotic chromosome condensation." [GO_REF:0000058, GOC:TermGenie, PMID:9490640] synonym: "activation of mitotic chromosome condensation" NARROW [GOC:TermGenie] synonym: "up regulation of mitotic chromosome condensation" EXACT [GOC:TermGenie] synonym: "up-regulation of mitotic chromosome condensation" EXACT [GOC:TermGenie] synonym: "upregulation of mitotic chromosome condensation" EXACT [GOC:TermGenie] is_a: GO:0090068 ! positive regulation of cell cycle process is_a: GO:1903379 ! regulation of mitotic chromosome condensation is_a: GO:1905821 ! positive regulation of chromosome condensation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007076 ! mitotic chromosome condensation relationship: positively_regulates GO:0007076 ! mitotic chromosome condensation created_by: al creation_date: 2014-08-26T13:57:29Z [Term] id: GO:1903412 name: response to bile acid namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus." [GO_REF:0000071, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21757002] is_a: GO:0014070 ! response to organic cyclic compound is_a: GO:0033993 ! response to lipid is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus intersection_of: has_primary_input CHEBI:3098 ! bile acid relationship: has_primary_input CHEBI:3098 ! bile acid created_by: rl creation_date: 2014-09-03T12:45:43Z [Term] id: GO:1903429 name: regulation of cell maturation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell maturation." [GO_REF:0000058, GOC:TermGenie, PMID:17459944] synonym: "regulation of functional differentiation" RELATED [GOC:TermGenie] is_a: GO:0060284 ! regulation of cell development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048469 ! cell maturation relationship: regulates GO:0048469 ! cell maturation created_by: jl creation_date: 2014-09-15T13:31:23Z [Term] id: GO:1903430 name: negative regulation of cell maturation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell maturation." [GO_REF:0000058, GOC:TermGenie, PMID:17459944] synonym: "down regulation of cell maturation" EXACT [GOC:TermGenie] synonym: "down regulation of functional differentiation" RELATED [GOC:TermGenie] synonym: "down-regulation of cell maturation" EXACT [GOC:TermGenie] synonym: "down-regulation of functional differentiation" RELATED [GOC:TermGenie] synonym: "downregulation of cell maturation" EXACT [GOC:TermGenie] synonym: "downregulation of functional differentiation" RELATED [GOC:TermGenie] synonym: "inhibition of cell maturation" NARROW [GOC:TermGenie] synonym: "inhibition of functional differentiation" RELATED [GOC:TermGenie] synonym: "negative regulation of functional differentiation" RELATED [GOC:TermGenie] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:1903429 ! regulation of cell maturation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048469 ! cell maturation relationship: negatively_regulates GO:0048469 ! cell maturation created_by: jl creation_date: 2014-09-15T13:31:32Z [Term] id: GO:1903431 name: positive regulation of cell maturation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell maturation." [GO_REF:0000058, GOC:TermGenie, PMID:17459944] synonym: "activation of cell maturation" NARROW [GOC:TermGenie] synonym: "activation of functional differentiation" RELATED [GOC:TermGenie] synonym: "positive regulation of functional differentiation" RELATED [GOC:TermGenie] synonym: "up regulation of cell maturation" EXACT [GOC:TermGenie] synonym: "up regulation of functional differentiation" RELATED [GOC:TermGenie] synonym: "up-regulation of cell maturation" EXACT [GOC:TermGenie] synonym: "up-regulation of functional differentiation" RELATED [GOC:TermGenie] synonym: "upregulation of cell maturation" EXACT [GOC:TermGenie] synonym: "upregulation of functional differentiation" RELATED [GOC:TermGenie] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:1903429 ! regulation of cell maturation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048469 ! cell maturation relationship: positively_regulates GO:0048469 ! cell maturation created_by: jl creation_date: 2014-09-15T13:31:41Z [Term] id: GO:1903441 name: protein localization to ciliary membrane namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within a ciliary membrane." [GO_REF:0000087, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:22139371] synonym: "protein localisation in ciliary membrane" EXACT [GOC:TermGenie] synonym: "protein localisation to ciliary membrane" EXACT [GOC:TermGenie] synonym: "protein localization in ciliary membrane" EXACT [GOC:TermGenie] is_a: GO:0061512 ! protein localization to cilium is_a: GO:0072657 ! protein localization to membrane is_a: GO:1990778 ! protein localization to cell periphery intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0060170 ! ciliary membrane relationship: has_target_end_location GO:0060170 ! ciliary membrane created_by: pr creation_date: 2014-09-16T15:15:39Z [Term] id: GO:1903510 name: mucopolysaccharide metabolic process namespace: biological_process def: "The chemical reactions and pathways involving mucopolysaccharide." [GO_REF:0000068, GOC:dph, GOC:TermGenie, PMID:4236091] synonym: "mucopolysaccharide metabolism" EXACT [GOC:TermGenie] is_a: GO:0030203 ! glycosaminoglycan metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:37395 ! mucopolysaccharide relationship: has_primary_input_or_output CHEBI:37395 ! mucopolysaccharide created_by: dph creation_date: 2014-10-01T21:55:47Z [Term] id: GO:1903522 name: regulation of blood circulation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of blood circulation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:10659969] synonym: "regulation of hemolymph circulation" RELATED [GOC:TermGenie] is_a: GO:0044057 ! regulation of system process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0008015 ! blood circulation relationship: regulates GO:0008015 ! blood circulation created_by: mr creation_date: 2014-10-06T18:38:56Z [Term] id: GO:1903523 name: negative regulation of blood circulation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of blood circulation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:10659969] synonym: "down regulation of blood circulation" EXACT [GOC:TermGenie] synonym: "down regulation of hemolymph circulation" RELATED [GOC:TermGenie] synonym: "down-regulation of blood circulation" EXACT [GOC:TermGenie] synonym: "down-regulation of hemolymph circulation" RELATED [GOC:TermGenie] synonym: "downregulation of blood circulation" EXACT [GOC:TermGenie] synonym: "downregulation of hemolymph circulation" RELATED [GOC:TermGenie] synonym: "inhibition of blood circulation" NARROW [GOC:TermGenie] synonym: "inhibition of hemolymph circulation" RELATED [GOC:TermGenie] synonym: "negative regulation of hemolymph circulation" RELATED [GOC:TermGenie] is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1903522 ! regulation of blood circulation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0008015 ! blood circulation relationship: negatively_regulates GO:0008015 ! blood circulation created_by: mr creation_date: 2014-10-06T18:39:05Z [Term] id: GO:1903524 name: positive regulation of blood circulation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of blood circulation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:10659969] synonym: "activation of blood circulation" NARROW [GOC:TermGenie] synonym: "activation of hemolymph circulation" RELATED [GOC:TermGenie] synonym: "positive regulation of hemolymph circulation" RELATED [GOC:TermGenie] synonym: "up regulation of blood circulation" EXACT [GOC:TermGenie] synonym: "up regulation of hemolymph circulation" RELATED [GOC:TermGenie] synonym: "up-regulation of blood circulation" EXACT [GOC:TermGenie] synonym: "up-regulation of hemolymph circulation" RELATED [GOC:TermGenie] synonym: "upregulation of blood circulation" EXACT [GOC:TermGenie] synonym: "upregulation of hemolymph circulation" RELATED [GOC:TermGenie] is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1903522 ! regulation of blood circulation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0008015 ! blood circulation relationship: positively_regulates GO:0008015 ! blood circulation created_by: mr creation_date: 2014-10-06T18:39:13Z [Term] id: GO:1903530 name: regulation of secretion by cell namespace: biological_process def: "Any process that modulates the frequency, rate or extent of secretion by cell." [GO_REF:0000058, GOC:pm, GOC:TermGenie, PMID:12130530] synonym: "regulation of cellular secretion" EXACT [GOC:TermGenie] is_a: GO:0050794 ! regulation of cellular process is_a: GO:0051046 ! regulation of secretion intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0032940 ! secretion by cell relationship: regulates GO:0032940 ! secretion by cell created_by: pm creation_date: 2014-10-08T13:24:59Z [Term] id: GO:1903531 name: negative regulation of secretion by cell namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of secretion by cell." [GO_REF:0000058, GOC:pm, GOC:TermGenie, PMID:12130530] synonym: "down regulation of cellular secretion" EXACT [GOC:TermGenie] synonym: "down regulation of secretion by cell" EXACT [GOC:TermGenie] synonym: "down-regulation of cellular secretion" EXACT [GOC:TermGenie] synonym: "down-regulation of secretion by cell" EXACT [GOC:TermGenie] synonym: "downregulation of cellular secretion" EXACT [GOC:TermGenie] synonym: "downregulation of secretion by cell" EXACT [GOC:TermGenie] synonym: "inhibition of cellular secretion" NARROW [GOC:TermGenie] synonym: "inhibition of secretion by cell" NARROW [GOC:TermGenie] synonym: "negative regulation of cellular secretion" EXACT [GOC:TermGenie] is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:0051048 ! negative regulation of secretion is_a: GO:1903530 ! regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0032940 ! secretion by cell relationship: negatively_regulates GO:0032940 ! secretion by cell created_by: pm creation_date: 2014-10-08T13:25:08Z [Term] id: GO:1903532 name: positive regulation of secretion by cell namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of secretion by cell." [GO_REF:0000058, GOC:pm, GOC:TermGenie, PMID:12130530] synonym: "activation of cellular secretion" NARROW [GOC:TermGenie] synonym: "activation of secretion by cell" NARROW [GOC:TermGenie] synonym: "positive regulation of cellular secretion" EXACT [GOC:TermGenie] synonym: "up regulation of cellular secretion" EXACT [GOC:TermGenie] synonym: "up regulation of secretion by cell" EXACT [GOC:TermGenie] synonym: "up-regulation of cellular secretion" EXACT [GOC:TermGenie] synonym: "up-regulation of secretion by cell" EXACT [GOC:TermGenie] synonym: "upregulation of cellular secretion" EXACT [GOC:TermGenie] synonym: "upregulation of secretion by cell" EXACT [GOC:TermGenie] is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:0051047 ! positive regulation of secretion is_a: GO:1903530 ! regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0032940 ! secretion by cell relationship: positively_regulates GO:0032940 ! secretion by cell created_by: pm creation_date: 2014-10-08T13:25:17Z [Term] id: GO:1903537 name: meiotic cell cycle process involved in oocyte maturation namespace: biological_process def: "Any meiotic cell cycle process that is involved in oocyte maturation." [GO_REF:0000060, GOC:jz, GOC:TermGenie, PMID:25212395] synonym: "meiosis involved in oocyte maturation" BROAD [] is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:1903046 ! meiotic cell cycle process intersection_of: GO:1903046 ! meiotic cell cycle process intersection_of: part_of GO:0001556 ! oocyte maturation relationship: part_of GO:0001556 ! oocyte maturation created_by: pr creation_date: 2014-10-09T10:46:14Z [Term] id: GO:1903538 name: regulation of meiotic cell cycle process involved in oocyte maturation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation." [GO_REF:0000058, GOC:jz, GOC:TermGenie, PMID:25212395] synonym: "regulation of meiosis involved in oocyte maturation" BROAD [GOC:TermGenie] is_a: GO:0010564 ! regulation of cell cycle process is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1903537 ! meiotic cell cycle process involved in oocyte maturation relationship: regulates GO:1903537 ! meiotic cell cycle process involved in oocyte maturation created_by: pr creation_date: 2014-10-09T10:52:38Z [Term] id: GO:1903541 name: regulation of exosomal secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of exosomal secretion." [GO_REF:0000058, GOC:TermGenie, PMID:24105262] synonym: "regulation of exosomal protein secretion" NARROW [GOC:TermGenie] synonym: "regulation of exosomal secretory pathway" EXACT [GOC:TermGenie] synonym: "regulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] synonym: "regulation of secretion of exosome" EXACT [GOC:TermGenie] is_a: GO:0017157 ! regulation of exocytosis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1990182 ! exosomal secretion relationship: regulates GO:1990182 ! exosomal secretion created_by: pga creation_date: 2014-10-14T11:38:52Z [Term] id: GO:1903542 name: negative regulation of exosomal secretion namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of exosomal secretion." [GO_REF:0000058, GOC:TermGenie, PMID:24105262] synonym: "down regulation of exosomal protein secretion" NARROW [GOC:TermGenie] synonym: "down regulation of exosomal secretion" EXACT [GOC:TermGenie] synonym: "down regulation of exosomal secretory pathway" EXACT [GOC:TermGenie] synonym: "down regulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] synonym: "down regulation of secretion of exosome" EXACT [GOC:TermGenie] synonym: "down-regulation of exosomal protein secretion" NARROW [GOC:TermGenie] synonym: "down-regulation of exosomal secretion" EXACT [GOC:TermGenie] synonym: "down-regulation of exosomal secretory pathway" EXACT [GOC:TermGenie] synonym: "down-regulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] synonym: "down-regulation of secretion of exosome" EXACT [GOC:TermGenie] synonym: "downregulation of exosomal protein secretion" NARROW [GOC:TermGenie] synonym: "downregulation of exosomal secretion" EXACT [GOC:TermGenie] synonym: "downregulation of exosomal secretory pathway" EXACT [GOC:TermGenie] synonym: "downregulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] synonym: "downregulation of secretion of exosome" EXACT [GOC:TermGenie] synonym: "inhibition of exosomal protein secretion" NARROW [GOC:TermGenie] synonym: "inhibition of exosomal secretion" NARROW [GOC:TermGenie] synonym: "inhibition of exosomal secretory pathway" NARROW [GOC:TermGenie] synonym: "inhibition of extracellular vesicular exosome secretion" NARROW [GOC:TermGenie] synonym: "inhibition of secretion of exosome" NARROW [GOC:TermGenie] synonym: "negative regulation of exosomal protein secretion" NARROW [GOC:TermGenie] synonym: "negative regulation of exosomal secretory pathway" EXACT [GOC:TermGenie] synonym: "negative regulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] synonym: "negative regulation of secretion of exosome" EXACT [GOC:TermGenie] is_a: GO:0045920 ! negative regulation of exocytosis is_a: GO:1903541 ! regulation of exosomal secretion intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1990182 ! exosomal secretion relationship: negatively_regulates GO:1990182 ! exosomal secretion created_by: pga creation_date: 2014-10-14T11:39:02Z [Term] id: GO:1903543 name: positive regulation of exosomal secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of exosomal secretion." [GO_REF:0000058, GOC:TermGenie, PMID:24105262] synonym: "activation of exosomal protein secretion" NARROW [GOC:TermGenie] synonym: "activation of exosomal secretion" NARROW [GOC:TermGenie] synonym: "activation of exosomal secretory pathway" NARROW [GOC:TermGenie] synonym: "activation of extracellular vesicular exosome secretion" NARROW [GOC:TermGenie] synonym: "activation of secretion of exosome" NARROW [GOC:TermGenie] synonym: "positive regulation of exosomal protein secretion" NARROW [GOC:TermGenie] synonym: "positive regulation of exosomal secretory pathway" EXACT [GOC:TermGenie] synonym: "positive regulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] synonym: "positive regulation of secretion of exosome" EXACT [GOC:TermGenie] synonym: "up regulation of exosomal protein secretion" NARROW [GOC:TermGenie] synonym: "up regulation of exosomal secretion" EXACT [GOC:TermGenie] synonym: "up regulation of exosomal secretory pathway" EXACT [GOC:TermGenie] synonym: "up regulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] synonym: "up regulation of secretion of exosome" EXACT [GOC:TermGenie] synonym: "up-regulation of exosomal protein secretion" NARROW [GOC:TermGenie] synonym: "up-regulation of exosomal secretion" EXACT [GOC:TermGenie] synonym: "up-regulation of exosomal secretory pathway" EXACT [GOC:TermGenie] synonym: "up-regulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] synonym: "up-regulation of secretion of exosome" EXACT [GOC:TermGenie] synonym: "upregulation of exosomal protein secretion" NARROW [GOC:TermGenie] synonym: "upregulation of exosomal secretion" EXACT [GOC:TermGenie] synonym: "upregulation of exosomal secretory pathway" EXACT [GOC:TermGenie] synonym: "upregulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] synonym: "upregulation of secretion of exosome" EXACT [GOC:TermGenie] is_a: GO:0044089 ! positive regulation of cellular component biogenesis is_a: GO:0045921 ! positive regulation of exocytosis is_a: GO:1903541 ! regulation of exosomal secretion intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1990182 ! exosomal secretion relationship: positively_regulates GO:1990182 ! exosomal secretion created_by: pga creation_date: 2014-10-14T11:39:10Z [Term] id: GO:1903551 name: regulation of extracellular exosome assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of extracellular vesicular exosome assembly." [GO_REF:0000058, GOC:TermGenie, PMID:24105262] synonym: "regulation of extracellular vesicular exosome assembly" EXACT [GOC:vesicles] is_a: GO:1902115 ! regulation of organelle assembly intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0071971 ! extracellular exosome assembly relationship: regulates GO:0071971 ! extracellular exosome assembly created_by: pga creation_date: 2014-10-20T15:37:25Z [Term] id: GO:1903552 name: negative regulation of extracellular exosome assembly namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of extracellular vesicular exosome assembly." [GO_REF:0000058, GOC:TermGenie, PMID:24105262] synonym: "down regulation of extracellular vesicular exosome assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of extracellular vesicular exosome assembly" EXACT [GOC:TermGenie] synonym: "downregulation of extracellular vesicular exosome assembly" EXACT [GOC:TermGenie] synonym: "inhibition of extracellular vesicular exosome assembly" NARROW [GOC:TermGenie] synonym: "negative regulation of extracellular vesicular exosome assembly" EXACT [GOC:vesicles] is_a: GO:1902116 ! negative regulation of organelle assembly is_a: GO:1903551 ! regulation of extracellular exosome assembly intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0071971 ! extracellular exosome assembly relationship: negatively_regulates GO:0071971 ! extracellular exosome assembly created_by: pga creation_date: 2014-10-20T15:37:33Z [Term] id: GO:1903553 name: positive regulation of extracellular exosome assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of extracellular vesicular exosome assembly." [GO_REF:0000058, GOC:TermGenie, PMID:24105262] synonym: "activation of extracellular vesicular exosome assembly" NARROW [GOC:TermGenie] synonym: "positive regulation of extracellular vesicular exosome assembly" RELATED [GOC:vesicles] synonym: "up regulation of extracellular vesicular exosome assembly" EXACT [GOC:TermGenie] synonym: "up-regulation of extracellular vesicular exosome assembly" EXACT [GOC:TermGenie] synonym: "upregulation of extracellular vesicular exosome assembly" EXACT [GOC:TermGenie] is_a: GO:1902117 ! positive regulation of organelle assembly is_a: GO:1903551 ! regulation of extracellular exosome assembly intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0071971 ! extracellular exosome assembly relationship: positively_regulates GO:0071971 ! extracellular exosome assembly created_by: pga creation_date: 2014-10-20T15:37:42Z [Term] id: GO:1903561 name: extracellular vesicle namespace: cellular_component def: "Any vesicle that is part of the extracellular region." [GO_REF:0000064, GOC:pm, GOC:TermGenie, PMID:24769233] synonym: "microparticle" RELATED [GOC:vesicles] is_a: GO:0031982 ! vesicle is_a: GO:0065010 ! extracellular membrane-bounded organelle intersection_of: GO:0031982 ! vesicle intersection_of: part_of GO:0005576 ! extracellular region created_by: jl creation_date: 2014-10-22T14:26:11Z [Term] id: GO:1903564 name: regulation of protein localization to cilium namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein localization to cilium." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:22072986] is_a: GO:0032880 ! regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0061512 ! protein localization to cilium relationship: regulates GO:0061512 ! protein localization to cilium created_by: krc creation_date: 2014-10-24T20:58:11Z [Term] id: GO:1903565 name: negative regulation of protein localization to cilium namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cilium." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:22072986] synonym: "down regulation of protein localization to cilium" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to cilium" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to cilium" EXACT [GOC:TermGenie] synonym: "inhibition of protein localization to cilium" NARROW [GOC:TermGenie] is_a: GO:1903564 ! regulation of protein localization to cilium is_a: GO:1903828 ! negative regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0061512 ! protein localization to cilium relationship: negatively_regulates GO:0061512 ! protein localization to cilium created_by: krc creation_date: 2014-10-24T20:58:20Z [Term] id: GO:1903566 name: positive regulation of protein localization to cilium namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein localization to cilium." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:22072986] synonym: "activation of protein localization to cilium" NARROW [GOC:TermGenie] synonym: "up regulation of protein localization to cilium" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to cilium" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to cilium" EXACT [GOC:TermGenie] is_a: GO:1903564 ! regulation of protein localization to cilium is_a: GO:1903829 ! positive regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0061512 ! protein localization to cilium relationship: positively_regulates GO:0061512 ! protein localization to cilium created_by: krc creation_date: 2014-10-24T20:58:28Z [Term] id: GO:1903567 name: regulation of protein localization to ciliary membrane namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein localization to ciliary membrane." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:22072986] synonym: "regulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] synonym: "regulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] synonym: "regulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] is_a: GO:1903564 ! regulation of protein localization to cilium is_a: GO:1904375 ! regulation of protein localization to cell periphery is_a: GO:1905475 ! regulation of protein localization to membrane intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1903441 ! protein localization to ciliary membrane relationship: regulates GO:1903441 ! protein localization to ciliary membrane created_by: krc creation_date: 2014-10-24T21:32:51Z [Term] id: GO:1903568 name: negative regulation of protein localization to ciliary membrane namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to ciliary membrane." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:22072986] synonym: "down regulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] synonym: "down regulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization to ciliary membrane" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to ciliary membrane" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to ciliary membrane" EXACT [GOC:TermGenie] synonym: "inhibition of protein localisation in ciliary membrane" NARROW [GOC:TermGenie] synonym: "inhibition of protein localisation to ciliary membrane" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization in ciliary membrane" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization to ciliary membrane" NARROW [GOC:TermGenie] synonym: "negative regulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] is_a: GO:1903565 ! negative regulation of protein localization to cilium is_a: GO:1903567 ! regulation of protein localization to ciliary membrane is_a: GO:1904376 ! negative regulation of protein localization to cell periphery is_a: GO:1905476 ! negative regulation of protein localization to membrane intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1903441 ! protein localization to ciliary membrane relationship: negatively_regulates GO:1903441 ! protein localization to ciliary membrane created_by: krc creation_date: 2014-10-24T21:32:59Z [Term] id: GO:1903569 name: positive regulation of protein localization to ciliary membrane namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein localization to ciliary membrane." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:22072986] synonym: "activation of protein localisation in ciliary membrane" NARROW [GOC:TermGenie] synonym: "activation of protein localisation to ciliary membrane" NARROW [GOC:TermGenie] synonym: "activation of protein localization in ciliary membrane" NARROW [GOC:TermGenie] synonym: "activation of protein localization to ciliary membrane" NARROW [GOC:TermGenie] synonym: "positive regulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization to ciliary membrane" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to ciliary membrane" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to ciliary membrane" EXACT [GOC:TermGenie] is_a: GO:1903566 ! positive regulation of protein localization to cilium is_a: GO:1903567 ! regulation of protein localization to ciliary membrane is_a: GO:1904377 ! positive regulation of protein localization to cell periphery is_a: GO:1905477 ! positive regulation of protein localization to membrane intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1903441 ! protein localization to ciliary membrane relationship: positively_regulates GO:1903441 ! protein localization to ciliary membrane created_by: krc creation_date: 2014-10-24T21:33:08Z [Term] id: GO:1903624 name: regulation of DNA catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of DNA catabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:2001740] synonym: "regulation of DNA breakdown" EXACT [GOC:TermGenie] synonym: "regulation of DNA catabolism" EXACT [GOC:TermGenie] synonym: "regulation of DNA degradation" EXACT [GOC:TermGenie] is_a: GO:0031329 ! regulation of cellular catabolic process is_a: GO:0051052 ! regulation of DNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006308 ! DNA catabolic process relationship: regulates GO:0006308 ! DNA catabolic process created_by: sl creation_date: 2014-11-19T22:36:35Z [Term] id: GO:1903625 name: negative regulation of DNA catabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of DNA catabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:2001740] synonym: "down regulation of DNA breakdown" EXACT [GOC:TermGenie] synonym: "down regulation of DNA catabolic process" EXACT [GOC:TermGenie] synonym: "down regulation of DNA catabolism" EXACT [GOC:TermGenie] synonym: "down regulation of DNA degradation" EXACT [GOC:TermGenie] synonym: "down-regulation of DNA breakdown" EXACT [GOC:TermGenie] synonym: "down-regulation of DNA catabolic process" EXACT [GOC:TermGenie] synonym: "down-regulation of DNA catabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of DNA degradation" EXACT [GOC:TermGenie] synonym: "downregulation of DNA breakdown" EXACT [GOC:TermGenie] synonym: "downregulation of DNA catabolic process" EXACT [GOC:TermGenie] synonym: "downregulation of DNA catabolism" EXACT [GOC:TermGenie] synonym: "downregulation of DNA degradation" EXACT [GOC:TermGenie] synonym: "inhibition of DNA breakdown" NARROW [GOC:TermGenie] synonym: "inhibition of DNA catabolic process" NARROW [GOC:TermGenie] synonym: "inhibition of DNA catabolism" NARROW [GOC:TermGenie] synonym: "inhibition of DNA degradation" NARROW [GOC:TermGenie] synonym: "negative regulation of DNA breakdown" EXACT [GOC:TermGenie] synonym: "negative regulation of DNA catabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of DNA degradation" EXACT [GOC:TermGenie] is_a: GO:0031330 ! negative regulation of cellular catabolic process is_a: GO:0051053 ! negative regulation of DNA metabolic process is_a: GO:1903624 ! regulation of DNA catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006308 ! DNA catabolic process relationship: negatively_regulates GO:0006308 ! DNA catabolic process created_by: sl creation_date: 2014-11-19T22:36:43Z [Term] id: GO:1903626 name: positive regulation of DNA catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of DNA catabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:2001740] synonym: "activation of DNA breakdown" NARROW [GOC:TermGenie] synonym: "activation of DNA catabolic process" NARROW [GOC:TermGenie] synonym: "activation of DNA catabolism" NARROW [GOC:TermGenie] synonym: "activation of DNA degradation" NARROW [GOC:TermGenie] synonym: "positive regulation of DNA breakdown" EXACT [GOC:TermGenie] synonym: "positive regulation of DNA catabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of DNA degradation" EXACT [GOC:TermGenie] synonym: "up regulation of DNA breakdown" EXACT [GOC:TermGenie] synonym: "up regulation of DNA catabolic process" EXACT [GOC:TermGenie] synonym: "up regulation of DNA catabolism" EXACT [GOC:TermGenie] synonym: "up regulation of DNA degradation" EXACT [GOC:TermGenie] synonym: "up-regulation of DNA breakdown" EXACT [GOC:TermGenie] synonym: "up-regulation of DNA catabolic process" EXACT [GOC:TermGenie] synonym: "up-regulation of DNA catabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of DNA degradation" EXACT [GOC:TermGenie] synonym: "upregulation of DNA breakdown" EXACT [GOC:TermGenie] synonym: "upregulation of DNA catabolic process" EXACT [GOC:TermGenie] synonym: "upregulation of DNA catabolism" EXACT [GOC:TermGenie] synonym: "upregulation of DNA degradation" EXACT [GOC:TermGenie] is_a: GO:0031331 ! positive regulation of cellular catabolic process is_a: GO:0051054 ! positive regulation of DNA metabolic process is_a: GO:1903624 ! regulation of DNA catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006308 ! DNA catabolic process relationship: positively_regulates GO:0006308 ! DNA catabolic process created_by: sl creation_date: 2014-11-19T22:36:51Z [Term] id: GO:1903697 name: negative regulation of microvillus assembly namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of microvillus assembly." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:22797597] synonym: "down regulation of microvillus assembly" EXACT [GOC:TermGenie] synonym: "down regulation of microvillus biogenesis" RELATED [GOC:TermGenie] synonym: "down-regulation of microvillus assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of microvillus biogenesis" RELATED [GOC:TermGenie] synonym: "downregulation of microvillus assembly" EXACT [GOC:TermGenie] synonym: "downregulation of microvillus biogenesis" RELATED [GOC:TermGenie] synonym: "inhibition of microvillus assembly" NARROW [GOC:TermGenie] synonym: "inhibition of microvillus biogenesis" RELATED [GOC:TermGenie] synonym: "negative regulation of microvillus biogenesis" RELATED [GOC:TermGenie] is_a: GO:0032534 ! regulation of microvillus assembly is_a: GO:0120033 ! negative regulation of plasma membrane bounded cell projection assembly intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030033 ! microvillus assembly relationship: negatively_regulates GO:0030033 ! microvillus assembly created_by: als creation_date: 2014-12-03T11:45:08Z [Term] id: GO:1903698 name: positive regulation of microvillus assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of microvillus assembly." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:22797597] synonym: "activation of microvillus assembly" NARROW [GOC:TermGenie] synonym: "activation of microvillus biogenesis" RELATED [GOC:TermGenie] synonym: "positive regulation of microvillus biogenesis" RELATED [GOC:TermGenie] synonym: "up regulation of microvillus assembly" EXACT [GOC:TermGenie] synonym: "up regulation of microvillus biogenesis" RELATED [GOC:TermGenie] synonym: "up-regulation of microvillus assembly" EXACT [GOC:TermGenie] synonym: "up-regulation of microvillus biogenesis" RELATED [GOC:TermGenie] synonym: "upregulation of microvillus assembly" EXACT [GOC:TermGenie] synonym: "upregulation of microvillus biogenesis" RELATED [GOC:TermGenie] is_a: GO:0032534 ! regulation of microvillus assembly is_a: GO:0120034 ! positive regulation of plasma membrane bounded cell projection assembly intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030033 ! microvillus assembly relationship: positively_regulates GO:0030033 ! microvillus assembly created_by: als creation_date: 2014-12-03T11:45:17Z [Term] id: GO:1903701 name: substantia propria of cornea development namespace: biological_process def: "The process whose specific outcome is the progression of a substantia propria of cornea over time, from its formation to the mature structure." [GO_REF:0000094, GOC:TermGenie, PMID:12556382] synonym: "corneal stroma development" EXACT [GOC:TermGenie] synonym: "stroma of cornea development" EXACT [GOC:TermGenie] synonym: "substantia propria development" RELATED [GOC:TermGenie] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001777 ! substantia propria of cornea relationship: results_in_development_of UBERON:0001777 ! substantia propria of cornea created_by: cls creation_date: 2014-12-03T13:12:09Z [Term] id: GO:1903702 name: esophagus development namespace: biological_process def: "The process whose specific outcome is the progression of an esophagus over time, from its formation to the mature structure." [GO_REF:0000094, GOC:TermGenie, ISBN:0-683-40008-8] synonym: "esophageal development" EXACT [MGI:csmith] synonym: "gullet development" EXACT [GOC:TermGenie] synonym: "oesophagus development" EXACT [GOC:TermGenie] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001043 ! esophagus relationship: results_in_development_of UBERON:0001043 ! esophagus created_by: cls creation_date: 2014-12-03T14:41:30Z [Term] id: GO:1903706 name: regulation of hemopoiesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of hemopoiesis." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:20080761] comment: An example of this is Atg7 in mouse (UniProt symbol, Q9D906) in PMID:20080761, inferred from mutant phenotype. synonym: "regulation of blood cell biosynthesis" EXACT [GOC:TermGenie] synonym: "regulation of blood cell formation" EXACT [GOC:TermGenie] synonym: "regulation of haemopoiesis" EXACT [GOC:TermGenie] synonym: "regulation of hematopoiesis" EXACT [GOC:TermGenie] is_a: GO:0002682 ! regulation of immune system process is_a: GO:0060284 ! regulation of cell development is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030097 ! hemopoiesis relationship: regulates GO:0030097 ! hemopoiesis created_by: pad creation_date: 2014-12-04T15:34:13Z [Term] id: GO:1903707 name: negative regulation of hemopoiesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of hemopoiesis." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:20080761] comment: An example of this is Atg7 in mouse (UniProt symbol, Q9D906) in PMID:20080761, inferred from mutant phenotype. synonym: "down regulation of blood cell biosynthesis" EXACT [GOC:TermGenie] synonym: "down regulation of blood cell formation" EXACT [GOC:TermGenie] synonym: "down regulation of haemopoiesis" EXACT [GOC:TermGenie] synonym: "down regulation of hematopoiesis" EXACT [GOC:TermGenie] synonym: "down regulation of hemopoiesis" EXACT [GOC:TermGenie] synonym: "down-regulation of blood cell biosynthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of blood cell formation" EXACT [GOC:TermGenie] synonym: "down-regulation of haemopoiesis" EXACT [GOC:TermGenie] synonym: "down-regulation of hematopoiesis" EXACT [GOC:TermGenie] synonym: "down-regulation of hemopoiesis" EXACT [GOC:TermGenie] synonym: "downregulation of blood cell biosynthesis" EXACT [GOC:TermGenie] synonym: "downregulation of blood cell formation" EXACT [GOC:TermGenie] synonym: "downregulation of haemopoiesis" EXACT [GOC:TermGenie] synonym: "downregulation of hematopoiesis" EXACT [GOC:TermGenie] synonym: "downregulation of hemopoiesis" EXACT [GOC:TermGenie] synonym: "inhibition of blood cell biosynthesis" NARROW [GOC:TermGenie] synonym: "inhibition of blood cell formation" NARROW [GOC:TermGenie] synonym: "inhibition of haemopoiesis" NARROW [GOC:TermGenie] synonym: "inhibition of hematopoiesis" NARROW [GOC:TermGenie] synonym: "inhibition of hemopoiesis" NARROW [GOC:TermGenie] synonym: "negative regulation of blood cell biosynthesis" EXACT [GOC:TermGenie] synonym: "negative regulation of blood cell formation" EXACT [GOC:TermGenie] synonym: "negative regulation of haemopoiesis" EXACT [GOC:TermGenie] synonym: "negative regulation of hematopoiesis" EXACT [GOC:TermGenie] is_a: GO:0002683 ! negative regulation of immune system process is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1903706 ! regulation of hemopoiesis intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030097 ! hemopoiesis relationship: negatively_regulates GO:0030097 ! hemopoiesis created_by: pad creation_date: 2014-12-04T15:34:21Z [Term] id: GO:1903708 name: positive regulation of hemopoiesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of hemopoiesis." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:20080761] comment: An example of this is Atg7 in mouse (UniProt symbol, Q9D906) in PMID:20080761, inferred from mutant phenotype. synonym: "activation of blood cell biosynthesis" NARROW [GOC:TermGenie] synonym: "activation of blood cell formation" NARROW [GOC:TermGenie] synonym: "activation of haemopoiesis" NARROW [GOC:TermGenie] synonym: "activation of hematopoiesis" NARROW [GOC:TermGenie] synonym: "activation of hemopoiesis" NARROW [GOC:TermGenie] synonym: "positive regulation of blood cell biosynthesis" EXACT [GOC:TermGenie] synonym: "positive regulation of blood cell formation" EXACT [GOC:TermGenie] synonym: "positive regulation of haemopoiesis" EXACT [GOC:TermGenie] synonym: "positive regulation of hematopoiesis" EXACT [GOC:TermGenie] synonym: "up regulation of blood cell biosynthesis" EXACT [GOC:TermGenie] synonym: "up regulation of blood cell formation" EXACT [GOC:TermGenie] synonym: "up regulation of haemopoiesis" EXACT [GOC:TermGenie] synonym: "up regulation of hematopoiesis" EXACT [GOC:TermGenie] synonym: "up regulation of hemopoiesis" EXACT [GOC:TermGenie] synonym: "up-regulation of blood cell biosynthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of blood cell formation" EXACT [GOC:TermGenie] synonym: "up-regulation of haemopoiesis" EXACT [GOC:TermGenie] synonym: "up-regulation of hematopoiesis" EXACT [GOC:TermGenie] synonym: "up-regulation of hemopoiesis" EXACT [GOC:TermGenie] synonym: "upregulation of blood cell biosynthesis" EXACT [GOC:TermGenie] synonym: "upregulation of blood cell formation" EXACT [GOC:TermGenie] synonym: "upregulation of haemopoiesis" EXACT [GOC:TermGenie] synonym: "upregulation of hematopoiesis" EXACT [GOC:TermGenie] synonym: "upregulation of hemopoiesis" EXACT [GOC:TermGenie] is_a: GO:0002684 ! positive regulation of immune system process is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1903706 ! regulation of hemopoiesis intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030097 ! hemopoiesis relationship: positively_regulates GO:0030097 ! hemopoiesis created_by: pad creation_date: 2014-12-04T15:34:30Z [Term] id: GO:1903709 name: uterine gland development namespace: biological_process def: "The process whose specific outcome is the progression of an uterine gland over time, from its formation to the mature structure." [GO_REF:0000094, GOC:TermGenie, PMID:23619340] synonym: "endometrial gland development" EXACT [GOC:TermGenie] synonym: "endometrium gland development" EXACT [GOC:TermGenie] synonym: "glandulae uterinae development" RELATED [GOC:TermGenie] synonym: "glandular part of endometrium development" RELATED [GOC:TermGenie] synonym: "set of uterine glands development" RELATED [GOC:TermGenie] synonym: "uterine glands development" EXACT [GOC:TermGenie] synonym: "uterine glands set development" EXACT [GOC:TermGenie] is_a: GO:0048732 ! gland development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002451 ! endometrial gland relationship: results_in_development_of UBERON:0002451 ! endometrial gland created_by: cls creation_date: 2014-12-04T18:57:21Z [Term] id: GO:1903729 name: regulation of plasma membrane organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of plasma membrane organization." [GO_REF:0000058, GOC:TermGenie, PMID:24514900] synonym: "regulation of plasma membrane organisation" EXACT [GOC:TermGenie] synonym: "regulation of plasma membrane organization and biogenesis" RELATED [GOC:TermGenie] is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007009 ! plasma membrane organization relationship: regulates GO:0007009 ! plasma membrane organization created_by: al creation_date: 2014-12-10T18:59:44Z [Term] id: GO:1903778 name: protein localization to vacuolar membrane namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within a vacuolar membrane." [GO_REF:0000087, GOC:TermGenie, PMID:25378562] synonym: "protein localisation in vacuolar membrane" EXACT [GOC:TermGenie] synonym: "protein localisation to vacuolar membrane" EXACT [GOC:TermGenie] synonym: "protein localization in vacuolar membrane" EXACT [GOC:TermGenie] is_a: GO:0072657 ! protein localization to membrane is_a: GO:0072665 ! protein localization to vacuole intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0005774 ! vacuolar membrane relationship: has_target_end_location GO:0005774 ! vacuolar membrane created_by: mah creation_date: 2015-01-07T13:15:54Z [Term] id: GO:1903779 name: regulation of cardiac conduction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac conduction." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rph, GOC:TermGenie, PMID:12967627] is_a: GO:0008016 ! regulation of heart contraction intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0061337 ! cardiac conduction relationship: regulates GO:0061337 ! cardiac conduction created_by: rph creation_date: 2015-01-07T13:20:11Z [Term] id: GO:1903780 name: negative regulation of cardiac conduction namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac conduction." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rph, GOC:TermGenie, PMID:12967627] synonym: "down regulation of cardiac conduction" EXACT [GOC:TermGenie] synonym: "down-regulation of cardiac conduction" EXACT [GOC:TermGenie] synonym: "downregulation of cardiac conduction" EXACT [GOC:TermGenie] synonym: "inhibition of cardiac conduction" NARROW [GOC:TermGenie] is_a: GO:0048519 ! negative regulation of biological process is_a: GO:1903779 ! regulation of cardiac conduction intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0061337 ! cardiac conduction relationship: negatively_regulates GO:0061337 ! cardiac conduction created_by: rph creation_date: 2015-01-07T13:20:20Z [Term] id: GO:1903781 name: positive regulation of cardiac conduction namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cardiac conduction." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rph, GOC:TermGenie, PMID:12967627] synonym: "activation of cardiac conduction" NARROW [GOC:TermGenie] synonym: "up regulation of cardiac conduction" EXACT [GOC:TermGenie] synonym: "up-regulation of cardiac conduction" EXACT [GOC:TermGenie] synonym: "upregulation of cardiac conduction" EXACT [GOC:TermGenie] is_a: GO:0048518 ! positive regulation of biological process is_a: GO:1903779 ! regulation of cardiac conduction intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0061337 ! cardiac conduction relationship: positively_regulates GO:0061337 ! cardiac conduction created_by: rph creation_date: 2015-01-07T13:20:28Z [Term] id: GO:1903789 name: regulation of amino acid transmembrane transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of amino acid transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:16115814] synonym: "regulation of amino acid membrane transport" EXACT [GOC:TermGenie] is_a: GO:0034762 ! regulation of transmembrane transport is_a: GO:0051955 ! regulation of amino acid transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003333 ! amino acid transmembrane transport relationship: regulates GO:0003333 ! amino acid transmembrane transport created_by: al creation_date: 2015-01-08T17:42:18Z [Term] id: GO:1903795 name: regulation of inorganic anion transmembrane transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of inorganic anion transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:11336802] synonym: "regulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] synonym: "regulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] is_a: GO:0034762 ! regulation of transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0098661 ! inorganic anion transmembrane transport relationship: regulates GO:0098661 ! inorganic anion transmembrane transport created_by: sl creation_date: 2015-01-14T21:44:49Z [Term] id: GO:1903796 name: negative regulation of inorganic anion transmembrane transport namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of inorganic anion transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:11336802] synonym: "down regulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] synonym: "down regulation of inorganic anion transmembrane transport" EXACT [GOC:TermGenie] synonym: "down regulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] synonym: "down-regulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] synonym: "down-regulation of inorganic anion transmembrane transport" EXACT [GOC:TermGenie] synonym: "down-regulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] synonym: "downregulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] synonym: "downregulation of inorganic anion transmembrane transport" EXACT [GOC:TermGenie] synonym: "downregulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] synonym: "inhibition of inorganic anion membrane transport" NARROW [GOC:TermGenie] synonym: "inhibition of inorganic anion transmembrane transport" NARROW [GOC:TermGenie] synonym: "inhibition of transmembrane inorganic anion transport" NARROW [GOC:TermGenie] synonym: "negative regulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] synonym: "negative regulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] is_a: GO:0034763 ! negative regulation of transmembrane transport is_a: GO:1903795 ! regulation of inorganic anion transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0098661 ! inorganic anion transmembrane transport relationship: negatively_regulates GO:0098661 ! inorganic anion transmembrane transport created_by: sl creation_date: 2015-01-14T21:44:59Z [Term] id: GO:1903797 name: positive regulation of inorganic anion transmembrane transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of inorganic anion transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:11336802] synonym: "activation of inorganic anion membrane transport" NARROW [GOC:TermGenie] synonym: "activation of inorganic anion transmembrane transport" NARROW [GOC:TermGenie] synonym: "activation of transmembrane inorganic anion transport" NARROW [GOC:TermGenie] synonym: "positive regulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] synonym: "positive regulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] synonym: "up regulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] synonym: "up regulation of inorganic anion transmembrane transport" EXACT [GOC:TermGenie] synonym: "up regulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] synonym: "up-regulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] synonym: "up-regulation of inorganic anion transmembrane transport" EXACT [GOC:TermGenie] synonym: "up-regulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] synonym: "upregulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] synonym: "upregulation of inorganic anion transmembrane transport" EXACT [GOC:TermGenie] synonym: "upregulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] is_a: GO:0034764 ! positive regulation of transmembrane transport is_a: GO:1903795 ! regulation of inorganic anion transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0098661 ! inorganic anion transmembrane transport relationship: positively_regulates GO:0098661 ! inorganic anion transmembrane transport created_by: sl creation_date: 2015-01-14T21:45:08Z [Term] id: GO:1903825 name: organic acid transmembrane transport namespace: biological_process def: "The process in which an organic acid is transported across a membrane." [GO_REF:0000069, GOC:TermGenie] is_a: GO:0015849 ! organic acid transport is_a: GO:0055085 ! transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:64709 ! organic acid intersection_of: results_in_transport_across GO:0016020 ! membrane created_by: vw creation_date: 2015-01-20T10:20:58Z [Term] id: GO:1903828 name: negative regulation of protein localization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of a protein localization." [GO_REF:0000058, GOC:TermGenie, GOC:vw] synonym: "down regulation of cellular protein localisation" EXACT [GOC:TermGenie] synonym: "down regulation of cellular protein localization" EXACT [GOC:TermGenie] synonym: "down-regulation of cellular protein localisation" EXACT [GOC:TermGenie] synonym: "down-regulation of cellular protein localization" EXACT [GOC:TermGenie] synonym: "downregulation of cellular protein localisation" EXACT [GOC:TermGenie] synonym: "downregulation of cellular protein localization" EXACT [GOC:TermGenie] synonym: "inhibition of cellular protein localisation" NARROW [GOC:TermGenie] synonym: "inhibition of cellular protein localization" NARROW [GOC:TermGenie] synonym: "negative regulation of cellular protein localisation" EXACT [GOC:TermGenie] synonym: "negative regulation of cellular protein localization" EXACT [] is_a: GO:0032880 ! regulation of protein localization is_a: GO:0048523 ! negative regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0008104 ! protein localization relationship: negatively_regulates GO:0008104 ! protein localization property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22021" xsd:anyURI created_by: jl creation_date: 2015-01-20T14:32:24Z [Term] id: GO:1903829 name: positive regulation of protein localization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of a protein localization." [GO_REF:0000058, GOC:TermGenie, GOC:vw] synonym: "positive regulation of cellular protein localisation" EXACT [GOC:TermGenie] synonym: "positive regulation of cellular protein localization" EXACT [] synonym: "up regulation of cellular protein localisation" EXACT [GOC:TermGenie] synonym: "up regulation of cellular protein localization" EXACT [GOC:TermGenie] synonym: "up-regulation of cellular protein localisation" EXACT [GOC:TermGenie] synonym: "up-regulation of cellular protein localization" EXACT [GOC:TermGenie] synonym: "upregulation of cellular protein localisation" EXACT [GOC:TermGenie] synonym: "upregulation of cellular protein localization" EXACT [GOC:TermGenie] is_a: GO:0032880 ! regulation of protein localization is_a: GO:0048522 ! positive regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0008104 ! protein localization relationship: positively_regulates GO:0008104 ! protein localization property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22021" xsd:anyURI created_by: jl creation_date: 2015-01-20T14:32:33Z [Term] id: GO:1903847 name: regulation of aorta morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of aorta morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22269326] is_a: GO:1905651 ! regulation of artery morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0035909 ! aorta morphogenesis relationship: regulates GO:0035909 ! aorta morphogenesis created_by: rph creation_date: 2015-01-23T14:00:51Z [Term] id: GO:1903848 name: negative regulation of aorta morphogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of aorta morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22269326] synonym: "down regulation of aorta morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of aorta morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of aorta morphogenesis" EXACT [GOC:TermGenie] synonym: "inhibition of aorta morphogenesis" NARROW [GOC:TermGenie] is_a: GO:1903847 ! regulation of aorta morphogenesis is_a: GO:1905652 ! negative regulation of artery morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0035909 ! aorta morphogenesis relationship: negatively_regulates GO:0035909 ! aorta morphogenesis created_by: rph creation_date: 2015-01-23T14:01:01Z [Term] id: GO:1903849 name: positive regulation of aorta morphogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of aorta morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22269326] synonym: "activation of aorta morphogenesis" NARROW [GOC:TermGenie] synonym: "up regulation of aorta morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of aorta morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of aorta morphogenesis" EXACT [GOC:TermGenie] is_a: GO:1903847 ! regulation of aorta morphogenesis is_a: GO:1905653 ! positive regulation of artery morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0035909 ! aorta morphogenesis relationship: positively_regulates GO:0035909 ! aorta morphogenesis created_by: rph creation_date: 2015-01-23T14:01:09Z [Term] id: GO:1903867 name: extraembryonic membrane development namespace: biological_process def: "The process whose specific outcome is the progression of an extraembryonic membrane over time, from its formation to the mature structure." [GO_REF:0000094, GOC:TermGenie, ISBN:0073040584] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005631 ! extraembryonic membrane relationship: results_in_development_of UBERON:0005631 ! extraembryonic membrane created_by: cjm creation_date: 2015-02-05T00:42:16Z [Term] id: GO:1903903 name: regulation of establishment of T cell polarity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of establishment of T cell polarity." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23575248] synonym: "regulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "regulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] synonym: "regulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "regulation of T cell polarization" EXACT [GOC:TermGenie] synonym: "regulation of T lymphocyte polarization" EXACT [GOC:TermGenie] synonym: "regulation of T-cell polarization" EXACT [GOC:TermGenie] is_a: GO:2000114 ! regulation of establishment of cell polarity intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001768 ! establishment of T cell polarity relationship: regulates GO:0001768 ! establishment of T cell polarity created_by: als creation_date: 2015-02-09T10:50:21Z [Term] id: GO:1903904 name: negative regulation of establishment of T cell polarity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of establishment of T cell polarity." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23575248] synonym: "down regulation of establishment of T cell polarity" EXACT [GOC:TermGenie] synonym: "down regulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "down regulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] synonym: "down regulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "down regulation of T cell polarization" EXACT [GOC:TermGenie] synonym: "down regulation of T lymphocyte polarization" EXACT [GOC:TermGenie] synonym: "down regulation of T-cell polarization" EXACT [GOC:TermGenie] synonym: "down-regulation of establishment of T cell polarity" EXACT [GOC:TermGenie] synonym: "down-regulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "down-regulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] synonym: "down-regulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "down-regulation of T cell polarization" EXACT [GOC:TermGenie] synonym: "down-regulation of T lymphocyte polarization" EXACT [GOC:TermGenie] synonym: "down-regulation of T-cell polarization" EXACT [GOC:TermGenie] synonym: "downregulation of establishment of T cell polarity" EXACT [GOC:TermGenie] synonym: "downregulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "downregulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] synonym: "downregulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "downregulation of T cell polarization" EXACT [GOC:TermGenie] synonym: "downregulation of T lymphocyte polarization" EXACT [GOC:TermGenie] synonym: "downregulation of T-cell polarization" EXACT [GOC:TermGenie] synonym: "inhibition of establishment of T cell polarity" NARROW [GOC:TermGenie] synonym: "inhibition of establishment of T lymphocyte polarity" NARROW [GOC:TermGenie] synonym: "inhibition of establishment of T-cell polarity" NARROW [GOC:TermGenie] synonym: "inhibition of establishment of T-lymphocyte polarity" NARROW [GOC:TermGenie] synonym: "inhibition of T cell polarization" NARROW [GOC:TermGenie] synonym: "inhibition of T lymphocyte polarization" NARROW [GOC:TermGenie] synonym: "inhibition of T-cell polarization" NARROW [GOC:TermGenie] synonym: "negative regulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "negative regulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] synonym: "negative regulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "negative regulation of T cell polarization" EXACT [GOC:TermGenie] synonym: "negative regulation of T lymphocyte polarization" EXACT [GOC:TermGenie] synonym: "negative regulation of T-cell polarization" EXACT [GOC:TermGenie] is_a: GO:0050868 ! negative regulation of T cell activation is_a: GO:1903903 ! regulation of establishment of T cell polarity intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001768 ! establishment of T cell polarity relationship: negatively_regulates GO:0001768 ! establishment of T cell polarity created_by: als creation_date: 2015-02-09T10:50:30Z [Term] id: GO:1903905 name: positive regulation of establishment of T cell polarity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of establishment of T cell polarity." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23575248] synonym: "activation of establishment of T cell polarity" NARROW [GOC:TermGenie] synonym: "activation of establishment of T lymphocyte polarity" NARROW [GOC:TermGenie] synonym: "activation of establishment of T-cell polarity" NARROW [GOC:TermGenie] synonym: "activation of establishment of T-lymphocyte polarity" NARROW [GOC:TermGenie] synonym: "activation of T cell polarization" NARROW [GOC:TermGenie] synonym: "activation of T lymphocyte polarization" NARROW [GOC:TermGenie] synonym: "activation of T-cell polarization" NARROW [GOC:TermGenie] synonym: "positive regulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "positive regulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] synonym: "positive regulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "positive regulation of T cell polarization" EXACT [GOC:TermGenie] synonym: "positive regulation of T lymphocyte polarization" EXACT [GOC:TermGenie] synonym: "positive regulation of T-cell polarization" EXACT [GOC:TermGenie] synonym: "up regulation of establishment of T cell polarity" EXACT [GOC:TermGenie] synonym: "up regulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "up regulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] synonym: "up regulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "up regulation of T cell polarization" EXACT [GOC:TermGenie] synonym: "up regulation of T lymphocyte polarization" EXACT [GOC:TermGenie] synonym: "up regulation of T-cell polarization" EXACT [GOC:TermGenie] synonym: "up-regulation of establishment of T cell polarity" EXACT [GOC:TermGenie] synonym: "up-regulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "up-regulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] synonym: "up-regulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "up-regulation of T cell polarization" EXACT [GOC:TermGenie] synonym: "up-regulation of T lymphocyte polarization" EXACT [GOC:TermGenie] synonym: "up-regulation of T-cell polarization" EXACT [GOC:TermGenie] synonym: "upregulation of establishment of T cell polarity" EXACT [GOC:TermGenie] synonym: "upregulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "upregulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] synonym: "upregulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "upregulation of T cell polarization" EXACT [GOC:TermGenie] synonym: "upregulation of T lymphocyte polarization" EXACT [GOC:TermGenie] synonym: "upregulation of T-cell polarization" EXACT [GOC:TermGenie] is_a: GO:0050870 ! positive regulation of T cell activation is_a: GO:1903903 ! regulation of establishment of T cell polarity intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001768 ! establishment of T cell polarity relationship: positively_regulates GO:0001768 ! establishment of T cell polarity created_by: als creation_date: 2015-02-09T10:50:40Z [Term] id: GO:1903941 name: negative regulation of respiratory gaseous exchange namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of respiratory gaseous exchange." [GO_REF:0000058, GOC:TermGenie, PMID:22819705] synonym: "down regulation of respiratory gaseous exchange" EXACT [GOC:TermGenie] synonym: "down-regulation of respiratory gaseous exchange" EXACT [GOC:TermGenie] synonym: "downregulation of respiratory gaseous exchange" EXACT [GOC:TermGenie] synonym: "inhibition of respiratory gaseous exchange" NARROW [GOC:TermGenie] is_a: GO:0043576 ! regulation of respiratory gaseous exchange is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007585 ! respiratory gaseous exchange by respiratory system relationship: negatively_regulates GO:0007585 ! respiratory gaseous exchange by respiratory system created_by: sl creation_date: 2015-02-17T20:26:24Z [Term] id: GO:1903942 name: positive regulation of respiratory gaseous exchange namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of respiratory gaseous exchange." [GO_REF:0000058, GOC:TermGenie, PMID:22819705] synonym: "activation of respiratory gaseous exchange" NARROW [GOC:TermGenie] synonym: "up regulation of respiratory gaseous exchange" EXACT [GOC:TermGenie] synonym: "up-regulation of respiratory gaseous exchange" EXACT [GOC:TermGenie] synonym: "upregulation of respiratory gaseous exchange" EXACT [GOC:TermGenie] is_a: GO:0043576 ! regulation of respiratory gaseous exchange is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007585 ! respiratory gaseous exchange by respiratory system relationship: positively_regulates GO:0007585 ! respiratory gaseous exchange by respiratory system created_by: sl creation_date: 2015-02-17T20:26:35Z [Term] id: GO:1903943 name: regulation of hepatocyte apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of hepatocyte apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:8649852] synonym: "regulation of hepatocyte apoptosis" NARROW [GOC:TermGenie] is_a: GO:1904035 ! regulation of epithelial cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0097284 ! hepatocyte apoptotic process relationship: regulates GO:0097284 ! hepatocyte apoptotic process created_by: sl creation_date: 2015-02-19T12:54:40Z [Term] id: GO:1903944 name: negative regulation of hepatocyte apoptotic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:8649852] synonym: "down regulation of hepatocyte apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of hepatocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of hepatocyte apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of hepatocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of hepatocyte apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of hepatocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "inhibition of hepatocyte apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of hepatocyte apoptotic process" NARROW [GOC:TermGenie] synonym: "negative regulation of hepatocyte apoptosis" NARROW [GOC:TermGenie] is_a: GO:1903943 ! regulation of hepatocyte apoptotic process is_a: GO:1904036 ! negative regulation of epithelial cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0097284 ! hepatocyte apoptotic process relationship: negatively_regulates GO:0097284 ! hepatocyte apoptotic process created_by: sl creation_date: 2015-02-19T12:54:50Z [Term] id: GO:1903945 name: positive regulation of hepatocyte apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of hepatocyte apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:8649852] synonym: "activation of hepatocyte apoptosis" NARROW [GOC:TermGenie] synonym: "activation of hepatocyte apoptotic process" NARROW [GOC:TermGenie] synonym: "positive regulation of hepatocyte apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of hepatocyte apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of hepatocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of hepatocyte apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of hepatocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of hepatocyte apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of hepatocyte apoptotic process" EXACT [GOC:TermGenie] is_a: GO:1903943 ! regulation of hepatocyte apoptotic process is_a: GO:1904037 ! positive regulation of epithelial cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0097284 ! hepatocyte apoptotic process relationship: positively_regulates GO:0097284 ! hepatocyte apoptotic process created_by: sl creation_date: 2015-02-19T12:54:59Z [Term] id: GO:1903950 name: negative regulation of AV node cell action potential namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of AV node cell action potential." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:nc, GOC:TermGenie, PMID:25281747] synonym: "down regulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "down regulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "down regulation of AV node cell action potential" EXACT [GOC:TermGenie] synonym: "down-regulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "down-regulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "down-regulation of AV node cell action potential" EXACT [GOC:TermGenie] synonym: "downregulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "downregulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "downregulation of AV node cell action potential" EXACT [GOC:TermGenie] synonym: "inhibition of atrioventricular node cardiac muscle cell action potential" NARROW [GOC:TermGenie] synonym: "inhibition of AV node cardiac muscle cell action potential" NARROW [GOC:TermGenie] synonym: "inhibition of AV node cell action potential" NARROW [GOC:TermGenie] synonym: "negative regulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "negative regulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] is_a: GO:0045759 ! negative regulation of action potential is_a: GO:0098904 ! regulation of AV node cell action potential intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0086016 ! AV node cell action potential relationship: negatively_regulates GO:0086016 ! AV node cell action potential created_by: nc creation_date: 2015-02-20T14:59:41Z [Term] id: GO:1903951 name: positive regulation of AV node cell action potential namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of AV node cell action potential." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:nc, GOC:TermGenie, PMID:25281747] synonym: "activation of atrioventricular node cardiac muscle cell action potential" NARROW [GOC:TermGenie] synonym: "activation of AV node cardiac muscle cell action potential" NARROW [GOC:TermGenie] synonym: "activation of AV node cell action potential" NARROW [GOC:TermGenie] synonym: "positive regulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "positive regulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "up regulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "up regulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "up regulation of AV node cell action potential" EXACT [GOC:TermGenie] synonym: "up-regulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "up-regulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "up-regulation of AV node cell action potential" EXACT [GOC:TermGenie] synonym: "upregulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "upregulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "upregulation of AV node cell action potential" EXACT [GOC:TermGenie] is_a: GO:0045760 ! positive regulation of action potential is_a: GO:0098904 ! regulation of AV node cell action potential intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0086016 ! AV node cell action potential relationship: positively_regulates GO:0086016 ! AV node cell action potential created_by: nc creation_date: 2015-02-20T14:59:50Z [Term] id: GO:1903975 name: regulation of glial cell migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of glial cell migration." [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:19100238] synonym: "regulation of glia cell migration" EXACT [GOC:TermGenie] is_a: GO:0030334 ! regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0008347 ! glial cell migration relationship: regulates GO:0008347 ! glial cell migration created_by: nc creation_date: 2015-03-02T15:13:31Z [Term] id: GO:1903976 name: negative regulation of glial cell migration namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of glial cell migration." [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:19100238] synonym: "down regulation of glia cell migration" EXACT [GOC:TermGenie] synonym: "down regulation of glial cell migration" EXACT [GOC:TermGenie] synonym: "down-regulation of glia cell migration" EXACT [GOC:TermGenie] synonym: "down-regulation of glial cell migration" EXACT [GOC:TermGenie] synonym: "downregulation of glia cell migration" EXACT [GOC:TermGenie] synonym: "downregulation of glial cell migration" EXACT [GOC:TermGenie] synonym: "inhibition of glia cell migration" NARROW [GOC:TermGenie] synonym: "inhibition of glial cell migration" NARROW [GOC:TermGenie] synonym: "negative regulation of glia cell migration" EXACT [GOC:TermGenie] is_a: GO:0030336 ! negative regulation of cell migration is_a: GO:1903975 ! regulation of glial cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0008347 ! glial cell migration relationship: negatively_regulates GO:0008347 ! glial cell migration created_by: nc creation_date: 2015-03-02T15:13:38Z [Term] id: GO:1903977 name: positive regulation of glial cell migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of glial cell migration." [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:19100238] synonym: "activation of glia cell migration" NARROW [GOC:TermGenie] synonym: "activation of glial cell migration" NARROW [GOC:TermGenie] synonym: "positive regulation of glia cell migration" EXACT [GOC:TermGenie] synonym: "up regulation of glia cell migration" EXACT [GOC:TermGenie] synonym: "up regulation of glial cell migration" EXACT [GOC:TermGenie] synonym: "up-regulation of glia cell migration" EXACT [GOC:TermGenie] synonym: "up-regulation of glial cell migration" EXACT [GOC:TermGenie] synonym: "upregulation of glia cell migration" EXACT [GOC:TermGenie] synonym: "upregulation of glial cell migration" EXACT [GOC:TermGenie] is_a: GO:0030335 ! positive regulation of cell migration is_a: GO:1903975 ! regulation of glial cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0008347 ! glial cell migration relationship: positively_regulates GO:0008347 ! glial cell migration created_by: nc creation_date: 2015-03-02T15:13:43Z [Term] id: GO:1904014 name: response to serotonin namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:1505525] is_a: GO:1901698 ! response to nitrogen compound intersection_of: GO:0050896 ! response to stimulus intersection_of: has_primary_input CHEBI:350546 ! serotonin(1+) relationship: has_primary_input CHEBI:350546 ! serotonin(1+) created_by: sl creation_date: 2015-03-06T19:33:54Z [Term] id: GO:1904018 name: positive regulation of vasculature development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of vasculature development." [GO_REF:0000058, GOC:TermGenie, PMID:21472453] synonym: "activation of vascular system development" RELATED [GOC:TermGenie] synonym: "activation of vasculature development" NARROW [GOC:TermGenie] synonym: "positive regulation of vascular system development" RELATED [GOC:TermGenie] synonym: "up regulation of vascular system development" RELATED [GOC:TermGenie] synonym: "up regulation of vasculature development" EXACT [GOC:TermGenie] synonym: "up-regulation of vascular system development" RELATED [GOC:TermGenie] synonym: "up-regulation of vasculature development" EXACT [GOC:TermGenie] synonym: "upregulation of vascular system development" RELATED [GOC:TermGenie] synonym: "upregulation of vasculature development" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1901342 ! regulation of vasculature development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001944 ! vasculature development relationship: positively_regulates GO:0001944 ! vasculature development created_by: sl creation_date: 2015-03-06T22:17:04Z [Term] id: GO:1904019 name: epithelial cell apoptotic process namespace: biological_process def: "Any apoptotic process in an epithelial cell." [GO_REF:0000085, GOC:TermGenie, PMID:19137015] synonym: "epithelial cell apoptosis" NARROW [GOC:TermGenie] synonym: "epitheliocyte apoptosis" NARROW [GOC:TermGenie] synonym: "epitheliocyte apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000066 ! epithelial cell relationship: occurs_in CL:0000066 ! epithelial cell property_value: RO:0002161 NCBITaxon:33090 property_value: RO:0002161 NCBITaxon_Union:0000023 created_by: sl creation_date: 2015-03-06T22:27:17Z [Term] id: GO:1904026 name: regulation of collagen fibril organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of collagen fibril organization." [GO_REF:0000058, GOC:TermGenie, PMID:25451920] synonym: "regulation of collagen fibril organisation" EXACT [GOC:TermGenie] synonym: "regulation of collagen fibrillogenesis" RELATED [] synonym: "regulation of fibrillar collagen organization" EXACT [GOC:TermGenie] is_a: GO:1902903 ! regulation of supramolecular fiber organization is_a: GO:1903053 ! regulation of extracellular matrix organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030199 ! collagen fibril organization relationship: regulates GO:0030199 ! collagen fibril organization created_by: ae creation_date: 2015-03-12T12:36:52Z [Term] id: GO:1904027 name: negative regulation of collagen fibril organization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of collagen fibril organization." [GO_REF:0000058, GOC:TermGenie, PMID:25451920] synonym: "down regulation of collagen fibril organisation" EXACT [GOC:TermGenie] synonym: "down regulation of collagen fibril organization" EXACT [GOC:TermGenie] synonym: "down regulation of fibrillar collagen organization" EXACT [GOC:TermGenie] synonym: "down-regulation of collagen fibril organisation" EXACT [GOC:TermGenie] synonym: "down-regulation of collagen fibril organization" EXACT [GOC:TermGenie] synonym: "down-regulation of fibrillar collagen organization" EXACT [GOC:TermGenie] synonym: "downregulation of collagen fibril organisation" EXACT [GOC:TermGenie] synonym: "downregulation of collagen fibril organization" EXACT [GOC:TermGenie] synonym: "downregulation of fibrillar collagen organization" EXACT [GOC:TermGenie] synonym: "inhibition of collagen fibril organisation" NARROW [GOC:TermGenie] synonym: "inhibition of collagen fibril organization" NARROW [GOC:TermGenie] synonym: "inhibition of fibrillar collagen organization" NARROW [GOC:TermGenie] synonym: "negative regulation of collagen fibril organisation" EXACT [GOC:TermGenie] synonym: "negative regulation of fibrillar collagen organization" EXACT [GOC:TermGenie] is_a: GO:1902904 ! negative regulation of supramolecular fiber organization is_a: GO:1903054 ! negative regulation of extracellular matrix organization is_a: GO:1904026 ! regulation of collagen fibril organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030199 ! collagen fibril organization relationship: negatively_regulates GO:0030199 ! collagen fibril organization created_by: ae creation_date: 2015-03-12T12:36:59Z [Term] id: GO:1904028 name: positive regulation of collagen fibril organization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of collagen fibril organization." [GO_REF:0000058, GOC:TermGenie, PMID:25451920] synonym: "activation of collagen fibril organisation" NARROW [GOC:TermGenie] synonym: "activation of collagen fibril organization" NARROW [GOC:TermGenie] synonym: "activation of fibrillar collagen organization" NARROW [GOC:TermGenie] synonym: "positive regulation of collagen fibril organisation" EXACT [GOC:TermGenie] synonym: "positive regulation of fibrillar collagen organization" EXACT [GOC:TermGenie] synonym: "up regulation of collagen fibril organisation" EXACT [GOC:TermGenie] synonym: "up regulation of collagen fibril organization" EXACT [GOC:TermGenie] synonym: "up regulation of fibrillar collagen organization" EXACT [GOC:TermGenie] synonym: "up-regulation of collagen fibril organisation" EXACT [GOC:TermGenie] synonym: "up-regulation of collagen fibril organization" EXACT [GOC:TermGenie] synonym: "up-regulation of fibrillar collagen organization" EXACT [GOC:TermGenie] synonym: "upregulation of collagen fibril organisation" EXACT [GOC:TermGenie] synonym: "upregulation of collagen fibril organization" EXACT [GOC:TermGenie] synonym: "upregulation of fibrillar collagen organization" EXACT [GOC:TermGenie] is_a: GO:1902905 ! positive regulation of supramolecular fiber organization is_a: GO:1903055 ! positive regulation of extracellular matrix organization is_a: GO:1904026 ! regulation of collagen fibril organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030199 ! collagen fibril organization relationship: positively_regulates GO:0030199 ! collagen fibril organization created_by: ae creation_date: 2015-03-12T12:37:06Z [Term] id: GO:1904035 name: regulation of epithelial cell apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of epithelial cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:19137015] synonym: "regulation of epithelial cell apoptosis" NARROW [GOC:TermGenie] synonym: "regulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie] synonym: "regulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1904019 ! epithelial cell apoptotic process relationship: regulates GO:1904019 ! epithelial cell apoptotic process created_by: sl creation_date: 2015-03-13T22:05:41Z [Term] id: GO:1904036 name: negative regulation of epithelial cell apoptotic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:19137015] synonym: "down regulation of epithelial cell apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of epithelial cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down regulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of epithelial cell apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of epithelial cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of epithelial cell apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of epithelial cell apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "inhibition of epithelial cell apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of epithelial cell apoptotic process" NARROW [GOC:TermGenie] synonym: "inhibition of epitheliocyte apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of epitheliocyte apoptotic process" NARROW [GOC:TermGenie] synonym: "negative regulation of epithelial cell apoptosis" NARROW [GOC:TermGenie] synonym: "negative regulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie] synonym: "negative regulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0043066 ! negative regulation of apoptotic process is_a: GO:1904035 ! regulation of epithelial cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1904019 ! epithelial cell apoptotic process relationship: negatively_regulates GO:1904019 ! epithelial cell apoptotic process created_by: sl creation_date: 2015-03-13T22:05:47Z [Term] id: GO:1904037 name: positive regulation of epithelial cell apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of epithelial cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:19137015] synonym: "activation of epithelial cell apoptosis" NARROW [GOC:TermGenie] synonym: "activation of epithelial cell apoptotic process" NARROW [GOC:TermGenie] synonym: "activation of epitheliocyte apoptosis" NARROW [GOC:TermGenie] synonym: "activation of epitheliocyte apoptotic process" NARROW [GOC:TermGenie] synonym: "positive regulation of epithelial cell apoptosis" NARROW [GOC:TermGenie] synonym: "positive regulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie] synonym: "positive regulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of epithelial cell apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of epithelial cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of epithelial cell apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of epithelial cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of epithelial cell apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of epithelial cell apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0043065 ! positive regulation of apoptotic process is_a: GO:1904035 ! regulation of epithelial cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1904019 ! epithelial cell apoptotic process relationship: positively_regulates GO:1904019 ! epithelial cell apoptotic process created_by: sl creation_date: 2015-03-13T22:05:53Z [Term] id: GO:1904054 name: regulation of cholangiocyte proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cholangiocyte proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24434010] synonym: "regulation of hepatoblast proliferation" EXACT [GOC:TermGenie] is_a: GO:0050678 ! regulation of epithelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1990705 ! cholangiocyte proliferation relationship: regulates GO:1990705 ! cholangiocyte proliferation created_by: sl creation_date: 2015-03-18T17:56:14Z [Term] id: GO:1904055 name: negative regulation of cholangiocyte proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cholangiocyte proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24434010] synonym: "down regulation of cholangiocyte proliferation" EXACT [GOC:TermGenie] synonym: "down regulation of hepatoblast proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of cholangiocyte proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of hepatoblast proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of cholangiocyte proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of hepatoblast proliferation" EXACT [GOC:TermGenie] synonym: "inhibition of cholangiocyte proliferation" NARROW [GOC:TermGenie] synonym: "inhibition of hepatoblast proliferation" NARROW [GOC:TermGenie] synonym: "negative regulation of hepatoblast proliferation" EXACT [GOC:TermGenie] is_a: GO:0050680 ! negative regulation of epithelial cell proliferation is_a: GO:1904054 ! regulation of cholangiocyte proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1990705 ! cholangiocyte proliferation relationship: negatively_regulates GO:1990705 ! cholangiocyte proliferation created_by: sl creation_date: 2015-03-18T17:56:20Z [Term] id: GO:1904056 name: positive regulation of cholangiocyte proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cholangiocyte proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24434010] synonym: "activation of cholangiocyte proliferation" NARROW [GOC:TermGenie] synonym: "activation of hepatoblast proliferation" NARROW [GOC:TermGenie] synonym: "positive regulation of hepatoblast proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of cholangiocyte proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of hepatoblast proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of cholangiocyte proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of hepatoblast proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of cholangiocyte proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of hepatoblast proliferation" EXACT [GOC:TermGenie] is_a: GO:0050679 ! positive regulation of epithelial cell proliferation is_a: GO:1904054 ! regulation of cholangiocyte proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1990705 ! cholangiocyte proliferation relationship: positively_regulates GO:1990705 ! cholangiocyte proliferation created_by: sl creation_date: 2015-03-18T17:56:26Z [Term] id: GO:1904057 name: negative regulation of sensory perception of pain namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of pain." [GO_REF:0000058, GOC:TermGenie, PMID:17167094] synonym: "down regulation of nociception" EXACT [GOC:TermGenie] synonym: "down regulation of perception of physiological pain" NARROW [GOC:TermGenie] synonym: "down regulation of sensory perception of pain" EXACT [GOC:TermGenie] synonym: "down-regulation of nociception" EXACT [GOC:TermGenie] synonym: "down-regulation of perception of physiological pain" NARROW [GOC:TermGenie] synonym: "down-regulation of sensory perception of pain" EXACT [GOC:TermGenie] synonym: "downregulation of nociception" EXACT [GOC:TermGenie] synonym: "downregulation of perception of physiological pain" NARROW [GOC:TermGenie] synonym: "downregulation of sensory perception of pain" EXACT [GOC:TermGenie] synonym: "inhibition of nociception" NARROW [GOC:TermGenie] synonym: "inhibition of perception of physiological pain" NARROW [GOC:TermGenie] synonym: "inhibition of sensory perception of pain" NARROW [GOC:TermGenie] synonym: "negative regulation of nociception" EXACT [GOC:TermGenie] synonym: "negative regulation of perception of physiological pain" NARROW [GOC:TermGenie] is_a: GO:0031645 ! negative regulation of nervous system process is_a: GO:0051930 ! regulation of sensory perception of pain intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0019233 ! sensory perception of pain relationship: negatively_regulates GO:0019233 ! sensory perception of pain created_by: sl creation_date: 2015-03-18T20:33:57Z [Term] id: GO:1904058 name: positive regulation of sensory perception of pain namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of sensory perception of pain." [GO_REF:0000058, GOC:TermGenie, PMID:17167094] synonym: "activation of nociception" NARROW [GOC:TermGenie] synonym: "activation of perception of physiological pain" NARROW [GOC:TermGenie] synonym: "activation of sensory perception of pain" NARROW [GOC:TermGenie] synonym: "positive regulation of nociception" EXACT [GOC:TermGenie] synonym: "positive regulation of perception of physiological pain" NARROW [GOC:TermGenie] synonym: "up regulation of nociception" EXACT [GOC:TermGenie] synonym: "up regulation of perception of physiological pain" NARROW [GOC:TermGenie] synonym: "up regulation of sensory perception of pain" EXACT [GOC:TermGenie] synonym: "up-regulation of nociception" EXACT [GOC:TermGenie] synonym: "up-regulation of perception of physiological pain" NARROW [GOC:TermGenie] synonym: "up-regulation of sensory perception of pain" EXACT [GOC:TermGenie] synonym: "upregulation of nociception" EXACT [GOC:TermGenie] synonym: "upregulation of perception of physiological pain" NARROW [GOC:TermGenie] synonym: "upregulation of sensory perception of pain" EXACT [GOC:TermGenie] is_a: GO:0031646 ! positive regulation of nervous system process is_a: GO:0051930 ! regulation of sensory perception of pain intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0019233 ! sensory perception of pain relationship: positively_regulates GO:0019233 ! sensory perception of pain created_by: sl creation_date: 2015-03-18T20:34:03Z [Term] id: GO:1904062 name: regulation of monoatomic cation transmembrane transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cation transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:15304482] synonym: "regulation of cation transmembrane transport" BROAD [] is_a: GO:0034765 ! regulation of monoatomic ion transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0098655 ! monoatomic cation transmembrane transport relationship: regulates GO:0098655 ! monoatomic cation transmembrane transport created_by: sl creation_date: 2015-03-18T21:11:43Z [Term] id: GO:1904063 name: negative regulation of cation transmembrane transport namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cation transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:15304482] synonym: "down regulation of cation transmembrane transport" EXACT [GOC:TermGenie] synonym: "down-regulation of cation transmembrane transport" EXACT [GOC:TermGenie] synonym: "downregulation of cation transmembrane transport" EXACT [GOC:TermGenie] synonym: "inhibition of cation transmembrane transport" NARROW [GOC:TermGenie] is_a: GO:0034766 ! negative regulation of monoatomic ion transmembrane transport is_a: GO:1904062 ! regulation of monoatomic cation transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0098655 ! monoatomic cation transmembrane transport relationship: negatively_regulates GO:0098655 ! monoatomic cation transmembrane transport created_by: sl creation_date: 2015-03-18T21:11:50Z [Term] id: GO:1904064 name: positive regulation of cation transmembrane transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cation transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:15304482] synonym: "activation of cation transmembrane transport" NARROW [GOC:TermGenie] synonym: "up regulation of cation transmembrane transport" EXACT [GOC:TermGenie] synonym: "up-regulation of cation transmembrane transport" EXACT [GOC:TermGenie] synonym: "upregulation of cation transmembrane transport" EXACT [GOC:TermGenie] is_a: GO:0034767 ! positive regulation of monoatomic ion transmembrane transport is_a: GO:1904062 ! regulation of monoatomic cation transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0098655 ! monoatomic cation transmembrane transport relationship: positively_regulates GO:0098655 ! monoatomic cation transmembrane transport created_by: sl creation_date: 2015-03-18T21:11:55Z [Term] id: GO:1904073 name: regulation of trophectodermal cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of trophectodermal cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24508636] synonym: "regulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0042127 ! regulation of cell population proliferation is_a: GO:0048638 ! regulation of developmental growth intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001834 ! trophectodermal cell proliferation relationship: regulates GO:0001834 ! trophectodermal cell proliferation created_by: tb creation_date: 2015-03-20T16:55:56Z [Term] id: GO:1904074 name: negative regulation of trophectodermal cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of trophectodermal cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24508636] synonym: "down regulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] synonym: "down regulation of trophectodermal cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of trophectodermal cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of trophectodermal cell proliferation" EXACT [GOC:TermGenie] synonym: "inhibition of trophectoderm cell proliferation" NARROW [GOC:TermGenie] synonym: "inhibition of trophectodermal cell proliferation" NARROW [GOC:TermGenie] synonym: "negative regulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:1904073 ! regulation of trophectodermal cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001834 ! trophectodermal cell proliferation relationship: negatively_regulates GO:0001834 ! trophectodermal cell proliferation created_by: tb creation_date: 2015-03-20T16:56:02Z [Term] id: GO:1904075 name: positive regulation of trophectodermal cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of trophectodermal cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24508636] synonym: "activation of trophectoderm cell proliferation" NARROW [GOC:TermGenie] synonym: "activation of trophectodermal cell proliferation" NARROW [GOC:TermGenie] synonym: "positive regulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of trophectodermal cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of trophectodermal cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of trophectodermal cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:1904073 ! regulation of trophectodermal cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001834 ! trophectodermal cell proliferation relationship: positively_regulates GO:0001834 ! trophectodermal cell proliferation created_by: tb creation_date: 2015-03-20T16:56:08Z [Term] id: GO:1904106 name: protein localization to microvillus namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within a microvillus." [GO_REF:0000087, GOC:kmv, GOC:TermGenie, PMID:25335890] synonym: "protein localisation in microvillus" EXACT [GOC:TermGenie] synonym: "protein localisation to microvillus" EXACT [GOC:TermGenie] synonym: "protein localization in microvillus" EXACT [GOC:TermGenie] is_a: GO:0008104 ! protein localization intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0005902 ! microvillus relationship: has_target_end_location GO:0005902 ! microvillus created_by: kmv creation_date: 2015-04-01T18:14:41Z [Term] id: GO:1904145 name: negative regulation of meiotic cell cycle process involved in oocyte maturation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation." [GO_REF:0000058, GOC:TermGenie, PMID:22674394] synonym: "down regulation of meiotic cell cycle process involved in oocyte maturation" EXACT [GOC:TermGenie] synonym: "down-regulation of meiotic cell cycle process involved in oocyte maturation" EXACT [GOC:TermGenie] synonym: "downregulation of meiotic cell cycle process involved in oocyte maturation" EXACT [GOC:TermGenie] synonym: "inhibition of meiotic cell cycle process involved in oocyte maturation" NARROW [GOC:TermGenie] is_a: GO:0010948 ! negative regulation of cell cycle process is_a: GO:0051447 ! negative regulation of meiotic cell cycle is_a: GO:1900194 ! negative regulation of oocyte maturation is_a: GO:1903538 ! regulation of meiotic cell cycle process involved in oocyte maturation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1903537 ! meiotic cell cycle process involved in oocyte maturation relationship: negatively_regulates GO:1903537 ! meiotic cell cycle process involved in oocyte maturation created_by: tb creation_date: 2015-04-14T15:59:22Z [Term] id: GO:1904146 name: positive regulation of meiotic cell cycle process involved in oocyte maturation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation." [GO_REF:0000058, GOC:TermGenie, PMID:22674394] synonym: "activation of meiotic cell cycle process involved in oocyte maturation" NARROW [GOC:TermGenie] synonym: "up regulation of meiotic cell cycle process involved in oocyte maturation" EXACT [GOC:TermGenie] synonym: "up-regulation of meiotic cell cycle process involved in oocyte maturation" EXACT [GOC:TermGenie] synonym: "upregulation of meiotic cell cycle process involved in oocyte maturation" EXACT [GOC:TermGenie] is_a: GO:0051446 ! positive regulation of meiotic cell cycle is_a: GO:0090068 ! positive regulation of cell cycle process is_a: GO:1903538 ! regulation of meiotic cell cycle process involved in oocyte maturation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1903537 ! meiotic cell cycle process involved in oocyte maturation relationship: positively_regulates GO:1903537 ! meiotic cell cycle process involved in oocyte maturation created_by: tb creation_date: 2015-04-14T15:59:28Z [Term] id: GO:1904170 name: regulation of bleb assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of bleb assembly." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:25651887] synonym: "regulation of cell blebbing" EXACT [GOC:TermGenie] is_a: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0032060 ! bleb assembly relationship: regulates GO:0032060 ! bleb assembly created_by: als creation_date: 2015-04-23T09:32:19Z [Term] id: GO:1904171 name: negative regulation of bleb assembly namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of bleb assembly." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:25651887] synonym: "down regulation of bleb assembly" EXACT [GOC:TermGenie] synonym: "down regulation of cell blebbing" EXACT [GOC:TermGenie] synonym: "down-regulation of bleb assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of cell blebbing" EXACT [GOC:TermGenie] synonym: "downregulation of bleb assembly" EXACT [GOC:TermGenie] synonym: "downregulation of cell blebbing" EXACT [GOC:TermGenie] synonym: "inhibition of bleb assembly" NARROW [GOC:TermGenie] synonym: "inhibition of cell blebbing" NARROW [GOC:TermGenie] synonym: "negative regulation of cell blebbing" EXACT [GOC:TermGenie] is_a: GO:0120033 ! negative regulation of plasma membrane bounded cell projection assembly is_a: GO:1904170 ! regulation of bleb assembly intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0032060 ! bleb assembly relationship: negatively_regulates GO:0032060 ! bleb assembly created_by: als creation_date: 2015-04-23T09:32:25Z [Term] id: GO:1904172 name: positive regulation of bleb assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of bleb assembly." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:25651887] synonym: "activation of bleb assembly" NARROW [GOC:TermGenie] synonym: "activation of cell blebbing" NARROW [GOC:TermGenie] synonym: "positive regulation of cell blebbing" EXACT [GOC:TermGenie] synonym: "up regulation of bleb assembly" EXACT [GOC:TermGenie] synonym: "up regulation of cell blebbing" EXACT [GOC:TermGenie] synonym: "up-regulation of bleb assembly" EXACT [GOC:TermGenie] synonym: "up-regulation of cell blebbing" EXACT [GOC:TermGenie] synonym: "upregulation of bleb assembly" EXACT [GOC:TermGenie] synonym: "upregulation of cell blebbing" EXACT [GOC:TermGenie] is_a: GO:0120034 ! positive regulation of plasma membrane bounded cell projection assembly is_a: GO:1904170 ! regulation of bleb assembly intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0032060 ! bleb assembly relationship: positively_regulates GO:0032060 ! bleb assembly created_by: als creation_date: 2015-04-23T09:32:31Z [Term] id: GO:1904177 name: regulation of adipose tissue development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of adipose tissue development." [GO_REF:0000058, GOC:TermGenie, PMID:23081848] synonym: "regulation of adipogenesis" RELATED [GOC:TermGenie] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060612 ! adipose tissue development relationship: regulates GO:0060612 ! adipose tissue development created_by: sl creation_date: 2015-04-29T20:01:01Z [Term] id: GO:1904178 name: negative regulation of adipose tissue development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of adipose tissue development." [GO_REF:0000058, GOC:TermGenie, PMID:23081848] synonym: "down regulation of adipogenesis" RELATED [GOC:TermGenie] synonym: "down regulation of adipose tissue development" EXACT [GOC:TermGenie] synonym: "down-regulation of adipogenesis" RELATED [GOC:TermGenie] synonym: "down-regulation of adipose tissue development" EXACT [GOC:TermGenie] synonym: "downregulation of adipogenesis" RELATED [GOC:TermGenie] synonym: "downregulation of adipose tissue development" EXACT [GOC:TermGenie] synonym: "inhibition of adipogenesis" RELATED [GOC:TermGenie] synonym: "inhibition of adipose tissue development" NARROW [GOC:TermGenie] synonym: "negative regulation of adipogenesis" RELATED [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1904177 ! regulation of adipose tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060612 ! adipose tissue development relationship: negatively_regulates GO:0060612 ! adipose tissue development created_by: sl creation_date: 2015-04-29T20:01:07Z [Term] id: GO:1904179 name: positive regulation of adipose tissue development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of adipose tissue development." [GO_REF:0000058, GOC:TermGenie, PMID:23081848] synonym: "activation of adipogenesis" RELATED [GOC:TermGenie] synonym: "activation of adipose tissue development" NARROW [GOC:TermGenie] synonym: "positive regulation of adipogenesis" RELATED [GOC:TermGenie] synonym: "up regulation of adipogenesis" RELATED [GOC:TermGenie] synonym: "up regulation of adipose tissue development" EXACT [GOC:TermGenie] synonym: "up-regulation of adipogenesis" RELATED [GOC:TermGenie] synonym: "up-regulation of adipose tissue development" EXACT [GOC:TermGenie] synonym: "upregulation of adipogenesis" RELATED [GOC:TermGenie] synonym: "upregulation of adipose tissue development" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1904177 ! regulation of adipose tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060612 ! adipose tissue development relationship: positively_regulates GO:0060612 ! adipose tissue development created_by: sl creation_date: 2015-04-29T20:01:13Z [Term] id: GO:1904192 name: regulation of cholangiocyte apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cholangiocyte apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:24498161] synonym: "regulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie] synonym: "regulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] synonym: "regulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] is_a: GO:1904035 ! regulation of epithelial cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1902488 ! cholangiocyte apoptotic process relationship: regulates GO:1902488 ! cholangiocyte apoptotic process created_by: sl creation_date: 2015-05-06T15:25:48Z [Term] id: GO:1904193 name: negative regulation of cholangiocyte apoptotic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cholangiocyte apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:24498161] synonym: "down regulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of cholangiocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "down regulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of cholangiocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of cholangiocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] synonym: "inhibition of cholangiocyte apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of cholangiocyte apoptotic process" NARROW [GOC:TermGenie] synonym: "inhibition of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of epithelial cell of bile duct apoptotic process" NARROW [GOC:TermGenie] synonym: "negative regulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie] synonym: "negative regulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] synonym: "negative regulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] is_a: GO:1904036 ! negative regulation of epithelial cell apoptotic process is_a: GO:1904192 ! regulation of cholangiocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1902488 ! cholangiocyte apoptotic process relationship: negatively_regulates GO:1902488 ! cholangiocyte apoptotic process created_by: sl creation_date: 2015-05-06T15:25:55Z [Term] id: GO:1904194 name: positive regulation of cholangiocyte apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cholangiocyte apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:24498161] synonym: "activation of cholangiocyte apoptosis" NARROW [GOC:TermGenie] synonym: "activation of cholangiocyte apoptotic process" NARROW [GOC:TermGenie] synonym: "activation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] synonym: "activation of epithelial cell of bile duct apoptotic process" NARROW [GOC:TermGenie] synonym: "positive regulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie] synonym: "positive regulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] synonym: "positive regulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of cholangiocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of cholangiocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of cholangiocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] is_a: GO:1904037 ! positive regulation of epithelial cell apoptotic process is_a: GO:1904192 ! regulation of cholangiocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1902488 ! cholangiocyte apoptotic process relationship: positively_regulates GO:1902488 ! cholangiocyte apoptotic process created_by: sl creation_date: 2015-05-06T15:26:00Z [Term] id: GO:1904204 name: regulation of skeletal muscle hypertrophy namespace: biological_process def: "Any process that modulates the frequency, rate or extent of skeletal muscle hypertrophy." [GO_REF:0000058, GOC:TermGenie, PMID:23470307] is_a: GO:0014733 ! regulation of skeletal muscle adaptation is_a: GO:0014743 ! regulation of muscle hypertrophy intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0014734 ! skeletal muscle hypertrophy relationship: regulates GO:0014734 ! skeletal muscle hypertrophy created_by: sl creation_date: 2015-05-08T17:38:13Z [Term] id: GO:1904205 name: negative regulation of skeletal muscle hypertrophy namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle hypertrophy." [GO_REF:0000058, GOC:TermGenie, PMID:23470307] synonym: "down regulation of skeletal muscle hypertrophy" EXACT [GOC:TermGenie] synonym: "down-regulation of skeletal muscle hypertrophy" EXACT [GOC:TermGenie] synonym: "downregulation of skeletal muscle hypertrophy" EXACT [GOC:TermGenie] synonym: "inhibition of skeletal muscle hypertrophy" NARROW [GOC:TermGenie] is_a: GO:0014741 ! negative regulation of muscle hypertrophy is_a: GO:0014745 ! negative regulation of muscle adaptation is_a: GO:1904204 ! regulation of skeletal muscle hypertrophy intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0014734 ! skeletal muscle hypertrophy relationship: negatively_regulates GO:0014734 ! skeletal muscle hypertrophy created_by: sl creation_date: 2015-05-08T17:38:19Z [Term] id: GO:1904206 name: positive regulation of skeletal muscle hypertrophy namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of skeletal muscle hypertrophy." [GO_REF:0000058, GOC:TermGenie, PMID:23470307] synonym: "activation of skeletal muscle hypertrophy" NARROW [GOC:TermGenie] synonym: "up regulation of skeletal muscle hypertrophy" EXACT [GOC:TermGenie] synonym: "up-regulation of skeletal muscle hypertrophy" EXACT [GOC:TermGenie] synonym: "upregulation of skeletal muscle hypertrophy" EXACT [GOC:TermGenie] is_a: GO:0014742 ! positive regulation of muscle hypertrophy is_a: GO:0014744 ! positive regulation of muscle adaptation is_a: GO:1904204 ! regulation of skeletal muscle hypertrophy intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0014734 ! skeletal muscle hypertrophy relationship: positively_regulates GO:0014734 ! skeletal muscle hypertrophy created_by: sl creation_date: 2015-05-08T17:38:25Z [Term] id: GO:1904251 name: regulation of bile acid metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of bile acid metabolic process." [GO_REF:0000058, GOC:bf, GOC:TermGenie] synonym: "regulation of bile acid metabolism" EXACT [GOC:TermGenie] is_a: GO:0019218 ! regulation of steroid metabolic process is_a: GO:0031323 ! regulation of cellular metabolic process is_a: GO:0062012 ! regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0008206 ! bile acid metabolic process relationship: regulates GO:0008206 ! bile acid metabolic process created_by: bf creation_date: 2015-05-20T11:04:28Z [Term] id: GO:1904252 name: negative regulation of bile acid metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of bile acid metabolic process." [GO_REF:0000058, GOC:bf, GOC:TermGenie] synonym: "down regulation of bile acid metabolic process" EXACT [GOC:TermGenie] synonym: "down regulation of bile acid metabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of bile acid metabolic process" EXACT [GOC:TermGenie] synonym: "down-regulation of bile acid metabolism" EXACT [GOC:TermGenie] synonym: "downregulation of bile acid metabolic process" EXACT [GOC:TermGenie] synonym: "downregulation of bile acid metabolism" EXACT [GOC:TermGenie] synonym: "inhibition of bile acid metabolic process" NARROW [GOC:TermGenie] synonym: "inhibition of bile acid metabolism" NARROW [GOC:TermGenie] synonym: "negative regulation of bile acid metabolism" EXACT [GOC:TermGenie] is_a: GO:0031324 ! negative regulation of cellular metabolic process is_a: GO:0045939 ! negative regulation of steroid metabolic process is_a: GO:0062014 ! negative regulation of small molecule metabolic process is_a: GO:1904251 ! regulation of bile acid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0008206 ! bile acid metabolic process relationship: negatively_regulates GO:0008206 ! bile acid metabolic process created_by: bf creation_date: 2015-05-20T11:04:35Z [Term] id: GO:1904253 name: positive regulation of bile acid metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of bile acid metabolic process." [GO_REF:0000058, GOC:bf, GOC:TermGenie] synonym: "activation of bile acid metabolic process" NARROW [GOC:TermGenie] synonym: "activation of bile acid metabolism" NARROW [GOC:TermGenie] synonym: "positive regulation of bile acid metabolism" EXACT [GOC:TermGenie] synonym: "up regulation of bile acid metabolic process" EXACT [GOC:TermGenie] synonym: "up regulation of bile acid metabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of bile acid metabolic process" EXACT [GOC:TermGenie] synonym: "up-regulation of bile acid metabolism" EXACT [GOC:TermGenie] synonym: "upregulation of bile acid metabolic process" EXACT [GOC:TermGenie] synonym: "upregulation of bile acid metabolism" EXACT [GOC:TermGenie] is_a: GO:0031325 ! positive regulation of cellular metabolic process is_a: GO:0045940 ! positive regulation of steroid metabolic process is_a: GO:0062013 ! positive regulation of small molecule metabolic process is_a: GO:1904251 ! regulation of bile acid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0008206 ! bile acid metabolic process relationship: positively_regulates GO:0008206 ! bile acid metabolic process created_by: bf creation_date: 2015-05-20T11:04:40Z [Term] id: GO:1904269 name: cell leading edge cell cortex namespace: cellular_component def: "The cell cortex of the leading edge of a cell." [GO_REF:0000064, GOC:kmv, GOC:TermGenie, PMID:25843030] synonym: "cell cortex of cell leading edge" EXACT [GOC:TermGenie] synonym: "cell cortex of front of cell" EXACT [GOC:TermGenie] synonym: "cell cortex of leading edge of cell" EXACT [GOC:TermGenie] synonym: "cell periphery of cell leading edge" RELATED [GOC:TermGenie] synonym: "cell periphery of front of cell" RELATED [GOC:TermGenie] synonym: "cell periphery of leading edge of cell" RELATED [GOC:TermGenie] synonym: "peripheral cytoplasm of cell leading edge" RELATED [GOC:TermGenie] synonym: "peripheral cytoplasm of front of cell" RELATED [GOC:TermGenie] synonym: "peripheral cytoplasm of leading edge of cell" RELATED [GOC:TermGenie] is_a: GO:0099738 ! cell cortex region intersection_of: GO:0099738 ! cell cortex region intersection_of: part_of GO:0031252 ! cell leading edge relationship: part_of GO:0031252 ! cell leading edge created_by: kmv creation_date: 2015-05-28T19:16:03Z [Term] id: GO:1904304 name: regulation of gastro-intestinal system smooth muscle contraction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of gastro-intestinal system smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:10821044] is_a: GO:0006940 ! regulation of smooth muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0014831 ! gastro-intestinal system smooth muscle contraction relationship: regulates GO:0014831 ! gastro-intestinal system smooth muscle contraction created_by: sl creation_date: 2015-06-09T23:18:42Z [Term] id: GO:1904305 name: negative regulation of gastro-intestinal system smooth muscle contraction namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of gastro-intestinal system smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:10821044] synonym: "down regulation of gastro-intestinal system smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "down-regulation of gastro-intestinal system smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "downregulation of gastro-intestinal system smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "inhibition of gastro-intestinal system smooth muscle contraction" NARROW [GOC:TermGenie] is_a: GO:0045986 ! negative regulation of smooth muscle contraction is_a: GO:1904304 ! regulation of gastro-intestinal system smooth muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0014831 ! gastro-intestinal system smooth muscle contraction relationship: negatively_regulates GO:0014831 ! gastro-intestinal system smooth muscle contraction created_by: sl creation_date: 2015-06-09T23:18:48Z [Term] id: GO:1904306 name: positive regulation of gastro-intestinal system smooth muscle contraction namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of gastro-intestinal system smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:10821044] synonym: "activation of gastro-intestinal system smooth muscle contraction" NARROW [GOC:TermGenie] synonym: "up regulation of gastro-intestinal system smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "up-regulation of gastro-intestinal system smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "upregulation of gastro-intestinal system smooth muscle contraction" EXACT [GOC:TermGenie] is_a: GO:0045987 ! positive regulation of smooth muscle contraction is_a: GO:1904304 ! regulation of gastro-intestinal system smooth muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0014831 ! gastro-intestinal system smooth muscle contraction relationship: positively_regulates GO:0014831 ! gastro-intestinal system smooth muscle contraction created_by: sl creation_date: 2015-06-09T23:18:54Z [Term] id: GO:1904318 name: regulation of smooth muscle contraction involved in micturition namespace: biological_process def: "Any process that modulates the frequency, rate or extent of smooth muscle contraction involved in micturition." [GO_REF:0000058, GOC:TermGenie, PMID:18562635] synonym: "regulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] synonym: "regulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] is_a: GO:0006940 ! regulation of smooth muscle contraction is_a: GO:0044062 ! regulation of excretion is_a: GO:0098801 ! regulation of renal system process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060083 ! smooth muscle contraction involved in micturition relationship: regulates GO:0060083 ! smooth muscle contraction involved in micturition created_by: sl creation_date: 2015-06-10T18:46:11Z [Term] id: GO:1904319 name: negative regulation of smooth muscle contraction involved in micturition namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle contraction involved in micturition." [GO_REF:0000058, GOC:TermGenie, PMID:18562635] synonym: "down regulation of smooth muscle contraction involved in micturition" EXACT [GOC:TermGenie] synonym: "down regulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] synonym: "down regulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] synonym: "down-regulation of smooth muscle contraction involved in micturition" EXACT [GOC:TermGenie] synonym: "down-regulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] synonym: "down-regulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] synonym: "downregulation of smooth muscle contraction involved in micturition" EXACT [GOC:TermGenie] synonym: "downregulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] synonym: "downregulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] synonym: "inhibition of smooth muscle contraction involved in micturition" NARROW [GOC:TermGenie] synonym: "inhibition of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] synonym: "inhibition of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] synonym: "negative regulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] synonym: "negative regulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] is_a: GO:0045986 ! negative regulation of smooth muscle contraction is_a: GO:1904318 ! regulation of smooth muscle contraction involved in micturition intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060083 ! smooth muscle contraction involved in micturition relationship: negatively_regulates GO:0060083 ! smooth muscle contraction involved in micturition created_by: sl creation_date: 2015-06-10T18:46:17Z [Term] id: GO:1904320 name: positive regulation of smooth muscle contraction involved in micturition namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of smooth muscle contraction involved in micturition." [GO_REF:0000058, GOC:TermGenie, PMID:18562635] synonym: "activation of smooth muscle contraction involved in micturition" NARROW [GOC:TermGenie] synonym: "activation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] synonym: "activation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] synonym: "positive regulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] synonym: "positive regulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] synonym: "up regulation of smooth muscle contraction involved in micturition" EXACT [GOC:TermGenie] synonym: "up regulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] synonym: "up regulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] synonym: "up-regulation of smooth muscle contraction involved in micturition" EXACT [GOC:TermGenie] synonym: "up-regulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] synonym: "up-regulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] synonym: "upregulation of smooth muscle contraction involved in micturition" EXACT [GOC:TermGenie] synonym: "upregulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] synonym: "upregulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] is_a: GO:0045987 ! positive regulation of smooth muscle contraction is_a: GO:1904318 ! regulation of smooth muscle contraction involved in micturition intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060083 ! smooth muscle contraction involved in micturition relationship: positively_regulates GO:0060083 ! smooth muscle contraction involved in micturition created_by: sl creation_date: 2015-06-10T18:46:23Z [Term] id: GO:1904341 name: regulation of colon smooth muscle contraction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of colon smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:24170253] is_a: GO:1904304 ! regulation of gastro-intestinal system smooth muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1990765 ! colon smooth muscle contraction relationship: regulates GO:1990765 ! colon smooth muscle contraction created_by: sl creation_date: 2015-06-11T21:16:58Z [Term] id: GO:1904342 name: negative regulation of colon smooth muscle contraction namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of colon smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:24170253] synonym: "down regulation of colon smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "down-regulation of colon smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "downregulation of colon smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "inhibition of colon smooth muscle contraction" NARROW [GOC:TermGenie] is_a: GO:1904305 ! negative regulation of gastro-intestinal system smooth muscle contraction is_a: GO:1904341 ! regulation of colon smooth muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1990765 ! colon smooth muscle contraction relationship: negatively_regulates GO:1990765 ! colon smooth muscle contraction created_by: sl creation_date: 2015-06-11T21:17:05Z [Term] id: GO:1904343 name: positive regulation of colon smooth muscle contraction namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of colon smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:24170253] synonym: "activation of colon smooth muscle contraction" NARROW [GOC:TermGenie] synonym: "up regulation of colon smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "up-regulation of colon smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "upregulation of colon smooth muscle contraction" EXACT [GOC:TermGenie] is_a: GO:1904306 ! positive regulation of gastro-intestinal system smooth muscle contraction is_a: GO:1904341 ! regulation of colon smooth muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1990765 ! colon smooth muscle contraction relationship: positively_regulates GO:1990765 ! colon smooth muscle contraction created_by: sl creation_date: 2015-06-11T21:17:11Z [Term] id: GO:1904344 name: regulation of gastric mucosal blood circulation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of gastric mucosal blood circulation." [GO_REF:0000058, GOC:TermGenie, PMID:10807413] synonym: "regulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] is_a: GO:1903522 ! regulation of blood circulation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1990768 ! gastric mucosal blood circulation relationship: regulates GO:1990768 ! gastric mucosal blood circulation created_by: sl creation_date: 2015-06-11T21:20:31Z [Term] id: GO:1904345 name: negative regulation of gastric mucosal blood circulation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of gastric mucosal blood circulation." [GO_REF:0000058, GOC:TermGenie, PMID:10807413] synonym: "down regulation of gastric mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "down regulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "down-regulation of gastric mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "down-regulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "downregulation of gastric mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "downregulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "inhibition of gastric mucosal blood circulation" NARROW [GOC:TermGenie] synonym: "inhibition of stomach mucosal blood circulation" NARROW [GOC:TermGenie] synonym: "negative regulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] is_a: GO:1903523 ! negative regulation of blood circulation is_a: GO:1904344 ! regulation of gastric mucosal blood circulation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1990768 ! gastric mucosal blood circulation relationship: negatively_regulates GO:1990768 ! gastric mucosal blood circulation created_by: sl creation_date: 2015-06-11T21:20:44Z [Term] id: GO:1904346 name: positive regulation of gastric mucosal blood circulation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of gastric mucosal blood circulation." [GO_REF:0000058, GOC:TermGenie, PMID:10807413] synonym: "activation of gastric mucosal blood circulation" NARROW [GOC:TermGenie] synonym: "activation of stomach mucosal blood circulation" NARROW [GOC:TermGenie] synonym: "positive regulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "up regulation of gastric mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "up regulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "up-regulation of gastric mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "up-regulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "upregulation of gastric mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "upregulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] is_a: GO:1903524 ! positive regulation of blood circulation is_a: GO:1904344 ! regulation of gastric mucosal blood circulation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1990768 ! gastric mucosal blood circulation relationship: positively_regulates GO:1990768 ! gastric mucosal blood circulation created_by: sl creation_date: 2015-06-11T21:20:50Z [Term] id: GO:1904347 name: regulation of small intestine smooth muscle contraction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of small intestine smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:11991626] is_a: GO:1904304 ! regulation of gastro-intestinal system smooth muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1990770 ! small intestine smooth muscle contraction relationship: regulates GO:1990770 ! small intestine smooth muscle contraction created_by: sl creation_date: 2015-06-11T21:37:34Z [Term] id: GO:1904348 name: negative regulation of small intestine smooth muscle contraction namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of small intestine smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:11991626] synonym: "down regulation of small intestine smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "down-regulation of small intestine smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "downregulation of small intestine smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "inhibition of small intestine smooth muscle contraction" NARROW [GOC:TermGenie] is_a: GO:1904305 ! negative regulation of gastro-intestinal system smooth muscle contraction is_a: GO:1904347 ! regulation of small intestine smooth muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1990770 ! small intestine smooth muscle contraction relationship: negatively_regulates GO:1990770 ! small intestine smooth muscle contraction created_by: sl creation_date: 2015-06-11T21:37:40Z [Term] id: GO:1904349 name: positive regulation of small intestine smooth muscle contraction namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of small intestine smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:11991626] synonym: "activation of small intestine smooth muscle contraction" NARROW [GOC:TermGenie] synonym: "up regulation of small intestine smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "up-regulation of small intestine smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "upregulation of small intestine smooth muscle contraction" EXACT [GOC:TermGenie] is_a: GO:1904306 ! positive regulation of gastro-intestinal system smooth muscle contraction is_a: GO:1904347 ! regulation of small intestine smooth muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1990770 ! small intestine smooth muscle contraction relationship: positively_regulates GO:1990770 ! small intestine smooth muscle contraction created_by: sl creation_date: 2015-06-11T21:37:46Z [Term] id: GO:1904350 name: regulation of protein catabolic process in the vacuole namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein catabolic process in the vacuole." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:25635054] synonym: "regulation of vacuolar protein breakdown" RELATED [GOC:TermGenie] synonym: "regulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie] synonym: "regulation of vacuolar protein catabolism" RELATED [GOC:TermGenie] synonym: "regulation of vacuolar protein degradation" RELATED [GOC:TermGenie] is_a: GO:0042176 ! regulation of protein catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007039 ! protein catabolic process in the vacuole relationship: regulates GO:0007039 ! protein catabolic process in the vacuole created_by: rl creation_date: 2015-06-12T09:10:36Z [Term] id: GO:1904351 name: negative regulation of protein catabolic process in the vacuole namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process in the vacuole." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:25635054] synonym: "down regulation of protein catabolic process in the vacuole" EXACT [GOC:TermGenie] synonym: "down regulation of vacuolar protein breakdown" RELATED [GOC:TermGenie] synonym: "down regulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie] synonym: "down regulation of vacuolar protein catabolism" RELATED [GOC:TermGenie] synonym: "down regulation of vacuolar protein degradation" RELATED [GOC:TermGenie] synonym: "down-regulation of protein catabolic process in the vacuole" EXACT [GOC:TermGenie] synonym: "down-regulation of vacuolar protein breakdown" RELATED [GOC:TermGenie] synonym: "down-regulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie] synonym: "down-regulation of vacuolar protein catabolism" RELATED [GOC:TermGenie] synonym: "down-regulation of vacuolar protein degradation" RELATED [GOC:TermGenie] synonym: "downregulation of protein catabolic process in the vacuole" EXACT [GOC:TermGenie] synonym: "downregulation of vacuolar protein breakdown" RELATED [GOC:TermGenie] synonym: "downregulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie] synonym: "downregulation of vacuolar protein catabolism" RELATED [GOC:TermGenie] synonym: "downregulation of vacuolar protein degradation" RELATED [GOC:TermGenie] synonym: "inhibition of protein catabolic process in the vacuole" NARROW [GOC:TermGenie] synonym: "inhibition of vacuolar protein breakdown" RELATED [GOC:TermGenie] synonym: "inhibition of vacuolar protein catabolic process" RELATED [GOC:TermGenie] synonym: "inhibition of vacuolar protein catabolism" RELATED [GOC:TermGenie] synonym: "inhibition of vacuolar protein degradation" RELATED [GOC:TermGenie] synonym: "negative regulation of vacuolar protein breakdown" RELATED [GOC:TermGenie] synonym: "negative regulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie] synonym: "negative regulation of vacuolar protein catabolism" RELATED [GOC:TermGenie] synonym: "negative regulation of vacuolar protein degradation" RELATED [GOC:TermGenie] is_a: GO:0042177 ! negative regulation of protein catabolic process is_a: GO:1904350 ! regulation of protein catabolic process in the vacuole intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007039 ! protein catabolic process in the vacuole relationship: negatively_regulates GO:0007039 ! protein catabolic process in the vacuole created_by: rl creation_date: 2015-06-12T09:10:42Z [Term] id: GO:1904352 name: positive regulation of protein catabolic process in the vacuole namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein catabolic process in the vacuole." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:25635054] synonym: "activation of protein catabolic process in the vacuole" NARROW [GOC:TermGenie] synonym: "activation of vacuolar protein breakdown" RELATED [GOC:TermGenie] synonym: "activation of vacuolar protein catabolic process" RELATED [GOC:TermGenie] synonym: "activation of vacuolar protein catabolism" RELATED [GOC:TermGenie] synonym: "activation of vacuolar protein degradation" RELATED [GOC:TermGenie] synonym: "positive regulation of vacuolar protein breakdown" RELATED [GOC:TermGenie] synonym: "positive regulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie] synonym: "positive regulation of vacuolar protein catabolism" RELATED [GOC:TermGenie] synonym: "positive regulation of vacuolar protein degradation" RELATED [GOC:TermGenie] synonym: "up regulation of protein catabolic process in the vacuole" EXACT [GOC:TermGenie] synonym: "up regulation of vacuolar protein breakdown" RELATED [GOC:TermGenie] synonym: "up regulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie] synonym: "up regulation of vacuolar protein catabolism" RELATED [GOC:TermGenie] synonym: "up regulation of vacuolar protein degradation" RELATED [GOC:TermGenie] synonym: "up-regulation of protein catabolic process in the vacuole" EXACT [GOC:TermGenie] synonym: "up-regulation of vacuolar protein breakdown" RELATED [GOC:TermGenie] synonym: "up-regulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie] synonym: "up-regulation of vacuolar protein catabolism" RELATED [GOC:TermGenie] synonym: "up-regulation of vacuolar protein degradation" RELATED [GOC:TermGenie] synonym: "upregulation of protein catabolic process in the vacuole" EXACT [GOC:TermGenie] synonym: "upregulation of vacuolar protein breakdown" RELATED [GOC:TermGenie] synonym: "upregulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie] synonym: "upregulation of vacuolar protein catabolism" RELATED [GOC:TermGenie] synonym: "upregulation of vacuolar protein degradation" RELATED [GOC:TermGenie] is_a: GO:0045732 ! positive regulation of protein catabolic process is_a: GO:1904350 ! regulation of protein catabolic process in the vacuole intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007039 ! protein catabolic process in the vacuole relationship: positively_regulates GO:0007039 ! protein catabolic process in the vacuole created_by: rl creation_date: 2015-06-12T09:10:49Z [Term] id: GO:1904375 name: regulation of protein localization to cell periphery namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein localization to cell periphery." [GO_REF:0000058, GOC:TermGenie, PMID:18216290] is_a: GO:0032880 ! regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1990778 ! protein localization to cell periphery relationship: regulates GO:1990778 ! protein localization to cell periphery created_by: sl creation_date: 2015-06-22T22:09:25Z [Term] id: GO:1904376 name: negative regulation of protein localization to cell periphery namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell periphery." [GO_REF:0000058, GOC:TermGenie, PMID:18216290] synonym: "down regulation of protein localization to cell periphery" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to cell periphery" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to cell periphery" EXACT [GOC:TermGenie] synonym: "inhibition of protein localization to cell periphery" NARROW [GOC:TermGenie] is_a: GO:1903828 ! negative regulation of protein localization is_a: GO:1904375 ! regulation of protein localization to cell periphery intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1990778 ! protein localization to cell periphery relationship: negatively_regulates GO:1990778 ! protein localization to cell periphery created_by: sl creation_date: 2015-06-22T22:09:32Z [Term] id: GO:1904377 name: positive regulation of protein localization to cell periphery namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein localization to cell periphery." [GO_REF:0000058, GOC:TermGenie, PMID:18216290] synonym: "activation of protein localization to cell periphery" NARROW [GOC:TermGenie] synonym: "up regulation of protein localization to cell periphery" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to cell periphery" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to cell periphery" EXACT [GOC:TermGenie] is_a: GO:1903829 ! positive regulation of protein localization is_a: GO:1904375 ! regulation of protein localization to cell periphery intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1990778 ! protein localization to cell periphery relationship: positively_regulates GO:1990778 ! protein localization to cell periphery created_by: sl creation_date: 2015-06-22T22:09:37Z [Term] id: GO:1904396 name: regulation of neuromuscular junction development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of neuromuscular junction development." [GO_REF:0000058, GOC:TermGenie, PMID:7722643] synonym: "regulation of neuromuscular junction organization" EXACT [GOC:TermGenie] synonym: "regulation of neuromuscular junction stability" RELATED [GOC:TermGenie] synonym: "regulation of NMJ stability" RELATED [GOC:TermGenie] is_a: GO:0050807 ! regulation of synapse organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007528 ! neuromuscular junction development relationship: regulates GO:0007528 ! neuromuscular junction development created_by: sl creation_date: 2015-06-23T19:23:42Z [Term] id: GO:1904397 name: negative regulation of neuromuscular junction development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular junction development." [GO_REF:0000058, GOC:TermGenie, PMID:7722643] synonym: "down regulation of neuromuscular junction development" EXACT [GOC:TermGenie] synonym: "down regulation of neuromuscular junction organization" EXACT [GOC:TermGenie] synonym: "down regulation of neuromuscular junction stability" RELATED [GOC:TermGenie] synonym: "down regulation of NMJ stability" RELATED [GOC:TermGenie] synonym: "down-regulation of neuromuscular junction development" EXACT [GOC:TermGenie] synonym: "down-regulation of neuromuscular junction organization" EXACT [GOC:TermGenie] synonym: "down-regulation of neuromuscular junction stability" RELATED [GOC:TermGenie] synonym: "down-regulation of NMJ stability" RELATED [GOC:TermGenie] synonym: "downregulation of neuromuscular junction development" EXACT [GOC:TermGenie] synonym: "downregulation of neuromuscular junction organization" EXACT [GOC:TermGenie] synonym: "downregulation of neuromuscular junction stability" RELATED [GOC:TermGenie] synonym: "downregulation of NMJ stability" RELATED [GOC:TermGenie] synonym: "inhibition of neuromuscular junction development" NARROW [GOC:TermGenie] synonym: "inhibition of neuromuscular junction organization" NARROW [GOC:TermGenie] synonym: "inhibition of neuromuscular junction stability" RELATED [GOC:TermGenie] synonym: "inhibition of NMJ stability" RELATED [GOC:TermGenie] synonym: "negative regulation of neuromuscular junction organization" EXACT [GOC:TermGenie] synonym: "negative regulation of neuromuscular junction stability" RELATED [GOC:TermGenie] synonym: "negative regulation of NMJ stability" RELATED [GOC:TermGenie] is_a: GO:1904396 ! regulation of neuromuscular junction development is_a: GO:1905809 ! negative regulation of synapse organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007528 ! neuromuscular junction development relationship: negatively_regulates GO:0007528 ! neuromuscular junction development created_by: sl creation_date: 2015-06-23T19:23:48Z [Term] id: GO:1904398 name: positive regulation of neuromuscular junction development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of neuromuscular junction development." [GO_REF:0000058, GOC:TermGenie, PMID:7722643] synonym: "activation of neuromuscular junction development" NARROW [GOC:TermGenie] synonym: "activation of neuromuscular junction organization" NARROW [GOC:TermGenie] synonym: "activation of neuromuscular junction stability" RELATED [GOC:TermGenie] synonym: "activation of NMJ stability" RELATED [GOC:TermGenie] synonym: "positive regulation of neuromuscular junction organization" EXACT [GOC:TermGenie] synonym: "positive regulation of neuromuscular junction stability" RELATED [GOC:TermGenie] synonym: "positive regulation of NMJ stability" RELATED [GOC:TermGenie] synonym: "up regulation of neuromuscular junction development" EXACT [GOC:TermGenie] synonym: "up regulation of neuromuscular junction organization" EXACT [GOC:TermGenie] synonym: "up regulation of neuromuscular junction stability" RELATED [GOC:TermGenie] synonym: "up regulation of NMJ stability" RELATED [GOC:TermGenie] synonym: "up-regulation of neuromuscular junction development" EXACT [GOC:TermGenie] synonym: "up-regulation of neuromuscular junction organization" EXACT [GOC:TermGenie] synonym: "up-regulation of neuromuscular junction stability" RELATED [GOC:TermGenie] synonym: "up-regulation of NMJ stability" RELATED [GOC:TermGenie] synonym: "upregulation of neuromuscular junction development" EXACT [GOC:TermGenie] synonym: "upregulation of neuromuscular junction organization" EXACT [GOC:TermGenie] synonym: "upregulation of neuromuscular junction stability" RELATED [GOC:TermGenie] synonym: "upregulation of NMJ stability" RELATED [GOC:TermGenie] is_a: GO:0051130 ! positive regulation of cellular component organization is_a: GO:1904396 ! regulation of neuromuscular junction development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007528 ! neuromuscular junction development relationship: positively_regulates GO:0007528 ! neuromuscular junction development created_by: sl creation_date: 2015-06-23T19:23:54Z [Term] id: GO:1904409 name: regulation of secretory granule organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of secretory granule organization." [GO_REF:0000058, GOC:TermGenie, PMID:15039777] synonym: "regulation of secretory granule organisation" EXACT [GOC:TermGenie] synonym: "regulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] is_a: GO:0033043 ! regulation of organelle organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0033363 ! secretory granule organization relationship: regulates GO:0033363 ! secretory granule organization created_by: sl creation_date: 2015-06-25T19:40:42Z [Term] id: GO:1904410 name: negative regulation of secretory granule organization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of secretory granule organization." [GO_REF:0000058, GOC:TermGenie, PMID:15039777] synonym: "down regulation of secretory granule organisation" EXACT [GOC:TermGenie] synonym: "down regulation of secretory granule organization" EXACT [GOC:TermGenie] synonym: "down regulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] synonym: "down-regulation of secretory granule organisation" EXACT [GOC:TermGenie] synonym: "down-regulation of secretory granule organization" EXACT [GOC:TermGenie] synonym: "down-regulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] synonym: "downregulation of secretory granule organisation" EXACT [GOC:TermGenie] synonym: "downregulation of secretory granule organization" EXACT [GOC:TermGenie] synonym: "downregulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] synonym: "inhibition of secretory granule organisation" NARROW [GOC:TermGenie] synonym: "inhibition of secretory granule organization" NARROW [GOC:TermGenie] synonym: "inhibition of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] synonym: "negative regulation of secretory granule organisation" EXACT [GOC:TermGenie] synonym: "negative regulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] is_a: GO:0010639 ! negative regulation of organelle organization is_a: GO:1904409 ! regulation of secretory granule organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0033363 ! secretory granule organization relationship: negatively_regulates GO:0033363 ! secretory granule organization created_by: sl creation_date: 2015-06-25T19:40:49Z [Term] id: GO:1904411 name: positive regulation of secretory granule organization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of secretory granule organization." [GO_REF:0000058, GOC:TermGenie, PMID:15039777] synonym: "activation of secretory granule organisation" NARROW [GOC:TermGenie] synonym: "activation of secretory granule organization" NARROW [GOC:TermGenie] synonym: "activation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] synonym: "positive regulation of secretory granule organisation" EXACT [GOC:TermGenie] synonym: "positive regulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] synonym: "up regulation of secretory granule organisation" EXACT [GOC:TermGenie] synonym: "up regulation of secretory granule organization" EXACT [GOC:TermGenie] synonym: "up regulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] synonym: "up-regulation of secretory granule organisation" EXACT [GOC:TermGenie] synonym: "up-regulation of secretory granule organization" EXACT [GOC:TermGenie] synonym: "up-regulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] synonym: "upregulation of secretory granule organisation" EXACT [GOC:TermGenie] synonym: "upregulation of secretory granule organization" EXACT [GOC:TermGenie] synonym: "upregulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] is_a: GO:0010638 ! positive regulation of organelle organization is_a: GO:1904409 ! regulation of secretory granule organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0033363 ! secretory granule organization relationship: positively_regulates GO:0033363 ! secretory granule organization created_by: sl creation_date: 2015-06-25T19:40:55Z [Term] id: GO:1904412 name: regulation of cardiac ventricle development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac ventricle development." [GO_REF:0000058, GOC:TermGenie, PMID:19590510] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003231 ! cardiac ventricle development relationship: regulates GO:0003231 ! cardiac ventricle development created_by: sl creation_date: 2015-06-25T19:52:15Z [Term] id: GO:1904413 name: negative regulation of cardiac ventricle development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle development." [GO_REF:0000058, GOC:TermGenie, PMID:19590510] synonym: "down regulation of cardiac ventricle development" EXACT [GOC:TermGenie] synonym: "down-regulation of cardiac ventricle development" EXACT [GOC:TermGenie] synonym: "downregulation of cardiac ventricle development" EXACT [GOC:TermGenie] synonym: "inhibition of cardiac ventricle development" NARROW [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1904412 ! regulation of cardiac ventricle development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0003231 ! cardiac ventricle development relationship: negatively_regulates GO:0003231 ! cardiac ventricle development created_by: sl creation_date: 2015-06-25T19:52:21Z [Term] id: GO:1904414 name: positive regulation of cardiac ventricle development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cardiac ventricle development." [GO_REF:0000058, GOC:TermGenie, PMID:19590510] synonym: "activation of cardiac ventricle development" NARROW [GOC:TermGenie] synonym: "up regulation of cardiac ventricle development" EXACT [GOC:TermGenie] synonym: "up-regulation of cardiac ventricle development" EXACT [GOC:TermGenie] synonym: "upregulation of cardiac ventricle development" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1904412 ! regulation of cardiac ventricle development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0003231 ! cardiac ventricle development relationship: positively_regulates GO:0003231 ! cardiac ventricle development created_by: sl creation_date: 2015-06-25T19:52:27Z [Term] id: GO:1904456 name: negative regulation of neuronal action potential namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of neuronal action potential." [GO_REF:0000058, GOC:TermGenie, PMID:25126967] synonym: "down regulation of generation of action potential" RELATED [GOC:TermGenie] synonym: "down regulation of neuronal action potential" EXACT [GOC:TermGenie] synonym: "down-regulation of generation of action potential" RELATED [GOC:TermGenie] synonym: "down-regulation of neuronal action potential" EXACT [GOC:TermGenie] synonym: "downregulation of generation of action potential" RELATED [GOC:TermGenie] synonym: "downregulation of neuronal action potential" EXACT [GOC:TermGenie] synonym: "inhibition of generation of action potential" RELATED [GOC:TermGenie] synonym: "inhibition of neuronal action potential" NARROW [GOC:TermGenie] synonym: "negative regulation of generation of action potential" RELATED [GOC:TermGenie] is_a: GO:0045759 ! negative regulation of action potential is_a: GO:0051970 ! negative regulation of transmission of nerve impulse is_a: GO:0098908 ! regulation of neuronal action potential intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0019228 ! neuronal action potential relationship: negatively_regulates GO:0019228 ! neuronal action potential created_by: sl creation_date: 2015-07-09T18:02:40Z [Term] id: GO:1904457 name: positive regulation of neuronal action potential namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of neuronal action potential." [GO_REF:0000058, GOC:TermGenie, PMID:25126967] synonym: "activation of generation of action potential" RELATED [GOC:TermGenie] synonym: "activation of neuronal action potential" NARROW [GOC:TermGenie] synonym: "positive regulation of generation of action potential" RELATED [GOC:TermGenie] synonym: "up regulation of generation of action potential" RELATED [GOC:TermGenie] synonym: "up regulation of neuronal action potential" EXACT [GOC:TermGenie] synonym: "up-regulation of generation of action potential" RELATED [GOC:TermGenie] synonym: "up-regulation of neuronal action potential" EXACT [GOC:TermGenie] synonym: "upregulation of generation of action potential" RELATED [GOC:TermGenie] synonym: "upregulation of neuronal action potential" EXACT [GOC:TermGenie] is_a: GO:0045760 ! positive regulation of action potential is_a: GO:0051971 ! positive regulation of transmission of nerve impulse is_a: GO:0098908 ! regulation of neuronal action potential intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0019228 ! neuronal action potential relationship: positively_regulates GO:0019228 ! neuronal action potential created_by: sl creation_date: 2015-07-09T18:02:46Z [Term] id: GO:1904484 name: cloacal gland development namespace: biological_process def: "The process whose specific outcome is the progression of a cloacal gland over time, from its formation to the mature structure." [GO_REF:0000094, GOC:mr, GOC:TermGenie, PMID:18805421] is_a: GO:0048732 ! gland development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0012478 ! cloacal gland relationship: results_in_development_of UBERON:0012478 ! cloacal gland created_by: mr creation_date: 2015-07-15T22:14:39Z [Term] id: GO:1904491 name: protein localization to ciliary transition zone namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within a ciliary transition zone." [GO_REF:0000087, GOC:kmv, GOC:TermGenie, PMID:21422230] synonym: "protein localisation in ciliary transition zone" EXACT [GOC:TermGenie] synonym: "protein localisation to ciliary transition zone" EXACT [GOC:TermGenie] synonym: "protein localization in ciliary transition zone" EXACT [GOC:TermGenie] is_a: GO:0061512 ! protein localization to cilium intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0035869 ! ciliary transition zone relationship: has_target_end_location GO:0035869 ! ciliary transition zone created_by: kmv creation_date: 2015-07-17T20:43:21Z [Term] id: GO:1904587 name: response to glycoprotein namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:14597422] synonym: "response to glycoproteins" EXACT [] is_a: GO:0010033 ! response to organic substance is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus intersection_of: has_primary_input CHEBI:17089 ! glycoprotein relationship: has_primary_input CHEBI:17089 ! glycoprotein created_by: sl creation_date: 2015-08-20T16:46:24Z [Term] id: GO:1904606 name: fat cell apoptotic process namespace: biological_process def: "Any apoptotic process in a fat cell." [GO_REF:0000085, GOC:TermGenie, PMID:17024416] synonym: "adipocyte apoptosis" NARROW [GOC:TermGenie] synonym: "adipocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "adipose cell apoptosis" NARROW [GOC:TermGenie] synonym: "adipose cell apoptotic process" EXACT [GOC:TermGenie] synonym: "fat cell apoptosis" NARROW [GOC:TermGenie] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000136 ! adipocyte relationship: occurs_in CL:0000136 ! adipocyte created_by: sl creation_date: 2015-08-27T18:13:06Z [Term] id: GO:1904649 name: regulation of fat cell apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of fat cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:17024416] synonym: "regulation of adipocyte apoptosis" NARROW [GOC:TermGenie] synonym: "regulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "regulation of adipose cell apoptosis" NARROW [GOC:TermGenie] synonym: "regulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] synonym: "regulation of fat cell apoptosis" NARROW [GOC:TermGenie] is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1904606 ! fat cell apoptotic process relationship: regulates GO:1904606 ! fat cell apoptotic process created_by: sl creation_date: 2015-08-31T20:59:28Z [Term] id: GO:1904650 name: negative regulation of fat cell apoptotic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of fat cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:17024416] synonym: "down regulation of adipocyte apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "down regulation of adipose cell apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down regulation of fat cell apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of fat cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of adipocyte apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of adipose cell apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of fat cell apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of fat cell apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of adipocyte apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of adipose cell apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of fat cell apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of fat cell apoptotic process" EXACT [GOC:TermGenie] synonym: "inhibition of adipocyte apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of adipocyte apoptotic process" NARROW [GOC:TermGenie] synonym: "inhibition of adipose cell apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of adipose cell apoptotic process" NARROW [GOC:TermGenie] synonym: "inhibition of fat cell apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of fat cell apoptotic process" NARROW [GOC:TermGenie] synonym: "negative regulation of adipocyte apoptosis" NARROW [GOC:TermGenie] synonym: "negative regulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "negative regulation of adipose cell apoptosis" NARROW [GOC:TermGenie] synonym: "negative regulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] synonym: "negative regulation of fat cell apoptosis" NARROW [GOC:TermGenie] is_a: GO:0043066 ! negative regulation of apoptotic process is_a: GO:1904649 ! regulation of fat cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1904606 ! fat cell apoptotic process relationship: negatively_regulates GO:1904606 ! fat cell apoptotic process created_by: sl creation_date: 2015-08-31T20:59:34Z [Term] id: GO:1904651 name: positive regulation of fat cell apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of fat cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:17024416] synonym: "activation of adipocyte apoptosis" NARROW [GOC:TermGenie] synonym: "activation of adipocyte apoptotic process" NARROW [GOC:TermGenie] synonym: "activation of adipose cell apoptosis" NARROW [GOC:TermGenie] synonym: "activation of adipose cell apoptotic process" NARROW [GOC:TermGenie] synonym: "activation of fat cell apoptosis" NARROW [GOC:TermGenie] synonym: "activation of fat cell apoptotic process" NARROW [GOC:TermGenie] synonym: "positive regulation of adipocyte apoptosis" NARROW [GOC:TermGenie] synonym: "positive regulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "positive regulation of adipose cell apoptosis" NARROW [GOC:TermGenie] synonym: "positive regulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] synonym: "positive regulation of fat cell apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of adipocyte apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of adipose cell apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of fat cell apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of fat cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of adipocyte apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of adipose cell apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of fat cell apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of fat cell apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of adipocyte apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of adipose cell apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of fat cell apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of fat cell apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0043065 ! positive regulation of apoptotic process is_a: GO:1904649 ! regulation of fat cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1904606 ! fat cell apoptotic process relationship: positively_regulates GO:1904606 ! fat cell apoptotic process created_by: sl creation_date: 2015-08-31T20:59:40Z [Term] id: GO:1904659 name: glucose transmembrane transport namespace: biological_process alt_id: GO:0015758 def: "The process in which glucose is transported across a membrane." [GO_REF:0000069, GOC:TermGenie, PMID:9090050] synonym: "glucose transport" RELATED [] is_a: GO:0008645 ! hexose transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:17234 ! glucose intersection_of: results_in_transport_across GO:0016020 ! membrane relationship: has_primary_input CHEBI:17234 ! glucose created_by: vw creation_date: 2015-09-04T17:20:16Z [Term] id: GO:1904671 name: negative regulation of cell differentiation involved in stem cell population maintenance namespace: biological_process def: "Any negative regulation of cell differentiation that is involved in stem cell population maintenance." [GO_REF:0000060, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607] synonym: "down regulation of cell differentiation involved in maintenance of pluripotency" RELATED [GOC:TermGenie] synonym: "down regulation of cell differentiation involved in stem cell population maintenance" EXACT [GOC:TermGenie] synonym: "down-regulation of cell differentiation involved in maintenance of pluripotency" RELATED [GOC:TermGenie] synonym: "down-regulation of cell differentiation involved in stem cell population maintenance" EXACT [GOC:TermGenie] synonym: "downregulation of cell differentiation involved in maintenance of pluripotency" RELATED [GOC:TermGenie] synonym: "downregulation of cell differentiation involved in stem cell population maintenance" EXACT [GOC:TermGenie] synonym: "inhibition of cell differentiation involved in maintenance of pluripotency" RELATED [GOC:TermGenie] synonym: "inhibition of cell differentiation involved in stem cell population maintenance" NARROW [GOC:TermGenie] synonym: "negative regulation of cell differentiation involved in maintenance of pluripotency" RELATED [GOC:TermGenie] is_a: GO:0045596 ! negative regulation of cell differentiation intersection_of: GO:0045596 ! negative regulation of cell differentiation intersection_of: part_of GO:0019827 ! stem cell population maintenance relationship: part_of GO:0019827 ! stem cell population maintenance created_by: tb creation_date: 2015-09-12T00:46:08Z [Term] id: GO:1904672 name: regulation of somatic stem cell population maintenance namespace: biological_process def: "Any process that modulates the frequency, rate or extent of somatic stem cell population maintenance." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607] is_a: GO:2000036 ! regulation of stem cell population maintenance intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0035019 ! somatic stem cell population maintenance relationship: regulates GO:0035019 ! somatic stem cell population maintenance created_by: rph creation_date: 2015-09-14T08:40:19Z [Term] id: GO:1904673 name: negative regulation of somatic stem cell population maintenance namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of somatic stem cell population maintenance." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607] synonym: "down regulation of somatic stem cell population maintenance" EXACT [GOC:TermGenie] synonym: "down-regulation of somatic stem cell population maintenance" EXACT [GOC:TermGenie] synonym: "downregulation of somatic stem cell population maintenance" EXACT [GOC:TermGenie] synonym: "inhibition of somatic stem cell population maintenance" NARROW [GOC:TermGenie] is_a: GO:1902455 ! negative regulation of stem cell population maintenance is_a: GO:1904672 ! regulation of somatic stem cell population maintenance intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0035019 ! somatic stem cell population maintenance relationship: negatively_regulates GO:0035019 ! somatic stem cell population maintenance created_by: rph creation_date: 2015-09-14T08:40:25Z [Term] id: GO:1904674 name: positive regulation of somatic stem cell population maintenance namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of somatic stem cell population maintenance." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607] synonym: "activation of somatic stem cell population maintenance" NARROW [GOC:TermGenie] synonym: "up regulation of somatic stem cell population maintenance" EXACT [GOC:TermGenie] synonym: "up-regulation of somatic stem cell population maintenance" EXACT [GOC:TermGenie] synonym: "upregulation of somatic stem cell population maintenance" EXACT [GOC:TermGenie] is_a: GO:1902459 ! positive regulation of stem cell population maintenance is_a: GO:1904672 ! regulation of somatic stem cell population maintenance intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0035019 ! somatic stem cell population maintenance relationship: positively_regulates GO:0035019 ! somatic stem cell population maintenance created_by: rph creation_date: 2015-09-14T08:40:32Z [Term] id: GO:1904675 name: regulation of somatic stem cell division namespace: biological_process def: "Any process that modulates the frequency, rate or extent of somatic stem cell division." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607] synonym: "regulation of somatic stem cell renewal" EXACT [GOC:TermGenie] is_a: GO:2000035 ! regulation of stem cell division intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048103 ! somatic stem cell division relationship: regulates GO:0048103 ! somatic stem cell division created_by: rph creation_date: 2015-09-14T08:47:22Z [Term] id: GO:1904676 name: negative regulation of somatic stem cell division namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of somatic stem cell division." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607] synonym: "down regulation of somatic stem cell division" EXACT [GOC:TermGenie] synonym: "down regulation of somatic stem cell renewal" EXACT [GOC:TermGenie] synonym: "down-regulation of somatic stem cell division" EXACT [GOC:TermGenie] synonym: "down-regulation of somatic stem cell renewal" EXACT [GOC:TermGenie] synonym: "downregulation of somatic stem cell division" EXACT [GOC:TermGenie] synonym: "downregulation of somatic stem cell renewal" EXACT [GOC:TermGenie] synonym: "inhibition of somatic stem cell division" NARROW [GOC:TermGenie] synonym: "inhibition of somatic stem cell renewal" NARROW [GOC:TermGenie] synonym: "negative regulation of somatic stem cell renewal" EXACT [GOC:TermGenie] is_a: GO:0051782 ! negative regulation of cell division is_a: GO:1904675 ! regulation of somatic stem cell division intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048103 ! somatic stem cell division relationship: negatively_regulates GO:0048103 ! somatic stem cell division created_by: rph creation_date: 2015-09-14T08:47:28Z [Term] id: GO:1904677 name: positive regulation of somatic stem cell division namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of somatic stem cell division." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607] synonym: "activation of somatic stem cell division" NARROW [GOC:TermGenie] synonym: "activation of somatic stem cell renewal" NARROW [GOC:TermGenie] synonym: "positive regulation of somatic stem cell renewal" EXACT [GOC:TermGenie] synonym: "up regulation of somatic stem cell division" EXACT [GOC:TermGenie] synonym: "up regulation of somatic stem cell renewal" EXACT [GOC:TermGenie] synonym: "up-regulation of somatic stem cell division" EXACT [GOC:TermGenie] synonym: "up-regulation of somatic stem cell renewal" EXACT [GOC:TermGenie] synonym: "upregulation of somatic stem cell division" EXACT [GOC:TermGenie] synonym: "upregulation of somatic stem cell renewal" EXACT [GOC:TermGenie] is_a: GO:0051781 ! positive regulation of cell division is_a: GO:1904675 ! regulation of somatic stem cell division intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048103 ! somatic stem cell division relationship: positively_regulates GO:0048103 ! somatic stem cell division created_by: rph creation_date: 2015-09-14T08:47:34Z [Term] id: GO:1904680 name: peptide transmembrane transporter activity namespace: molecular_function alt_id: GO:0015197 alt_id: GO:0015637 def: "Enables the transfer of a peptide from one side of a membrane to the other." [GO_REF:0000070, GOC:TermGenie, GOC:vw] synonym: "peptide transporter activity" RELATED [] synonym: "peptide uptake permease activity" RELATED [] xref: Reactome:R-HSA-1500817 "Glutathione is taken up by the bacterium" is_a: GO:0042887 ! amide transmembrane transporter activity intersection_of: GO:0005215 ! transporter activity intersection_of: has_primary_input CHEBI:16670 ! peptide intersection_of: results_in_transport_across GO:0016020 ! membrane relationship: has_primary_input CHEBI:16670 ! peptide created_by: tb creation_date: 2015-09-22T18:50:41Z [Term] id: GO:1904691 name: negative regulation of type B pancreatic cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24055447] synonym: "down regulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie] synonym: "down regulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie] synonym: "down regulation of type B pancreatic cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of type B pancreatic cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of type B pancreatic cell proliferation" EXACT [GOC:TermGenie] synonym: "inhibition of pancreatic B cell proliferation" NARROW [GOC:TermGenie] synonym: "inhibition of pancreatic beta cell proliferation" NARROW [GOC:TermGenie] synonym: "inhibition of type B pancreatic cell proliferation" NARROW [GOC:TermGenie] synonym: "negative regulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie] synonym: "negative regulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0050680 ! negative regulation of epithelial cell proliferation is_a: GO:0061469 ! regulation of type B pancreatic cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0044342 ! type B pancreatic cell proliferation relationship: negatively_regulates GO:0044342 ! type B pancreatic cell proliferation created_by: sl creation_date: 2015-09-25T15:23:38Z [Term] id: GO:1904692 name: positive regulation of type B pancreatic cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of type B pancreatic cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24055447] synonym: "activation of pancreatic B cell proliferation" NARROW [GOC:TermGenie] synonym: "activation of pancreatic beta cell proliferation" NARROW [GOC:TermGenie] synonym: "activation of type B pancreatic cell proliferation" NARROW [GOC:TermGenie] synonym: "positive regulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie] synonym: "positive regulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of type B pancreatic cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of type B pancreatic cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of type B pancreatic cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0050679 ! positive regulation of epithelial cell proliferation is_a: GO:0061469 ! regulation of type B pancreatic cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0044342 ! type B pancreatic cell proliferation relationship: positively_regulates GO:0044342 ! type B pancreatic cell proliferation created_by: sl creation_date: 2015-09-25T15:23:44Z [Term] id: GO:1904693 name: midbrain morphogenesis namespace: biological_process def: "The developmental process by which a midbrain is generated and organized." [GO_REF:0000083, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:21347250] synonym: "MB morphogenesis" BROAD [GOC:TermGenie] synonym: "mesencephalon morphogenesis" RELATED [GOC:TermGenie] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001891 ! midbrain relationship: part_of GO:0030901 ! midbrain development relationship: part_of GO:0048854 ! brain morphogenesis relationship: results_in_morphogenesis_of UBERON:0001891 ! midbrain created_by: bf creation_date: 2015-09-29T09:15:28Z [Term] id: GO:1904697 name: regulation of acinar cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of acinar cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:9788538] synonym: "regulation of acinic cell proliferation" EXACT [GOC:TermGenie] synonym: "regulation of acinous cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0050678 ! regulation of epithelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1990863 ! acinar cell proliferation relationship: regulates GO:1990863 ! acinar cell proliferation created_by: sl creation_date: 2015-09-30T15:19:50Z [Term] id: GO:1904698 name: negative regulation of acinar cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of acinar cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:9788538] synonym: "down regulation of acinar cell proliferation" EXACT [GOC:TermGenie] synonym: "down regulation of acinic cell proliferation" EXACT [GOC:TermGenie] synonym: "down regulation of acinous cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of acinar cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of acinic cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of acinous cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of acinar cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of acinic cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of acinous cell proliferation" EXACT [GOC:TermGenie] synonym: "inhibition of acinar cell proliferation" NARROW [GOC:TermGenie] synonym: "inhibition of acinic cell proliferation" NARROW [GOC:TermGenie] synonym: "inhibition of acinous cell proliferation" NARROW [GOC:TermGenie] synonym: "negative regulation of acinic cell proliferation" EXACT [GOC:TermGenie] synonym: "negative regulation of acinous cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0050680 ! negative regulation of epithelial cell proliferation is_a: GO:1904697 ! regulation of acinar cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1990863 ! acinar cell proliferation relationship: negatively_regulates GO:1990863 ! acinar cell proliferation created_by: sl creation_date: 2015-09-30T15:19:57Z [Term] id: GO:1904699 name: positive regulation of acinar cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of acinar cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:9788538] synonym: "activation of acinar cell proliferation" NARROW [GOC:TermGenie] synonym: "activation of acinic cell proliferation" NARROW [GOC:TermGenie] synonym: "activation of acinous cell proliferation" NARROW [GOC:TermGenie] synonym: "positive regulation of acinic cell proliferation" EXACT [GOC:TermGenie] synonym: "positive regulation of acinous cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of acinar cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of acinic cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of acinous cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of acinar cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of acinic cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of acinous cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of acinar cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of acinic cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of acinous cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0050679 ! positive regulation of epithelial cell proliferation is_a: GO:1904697 ! regulation of acinar cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1990863 ! acinar cell proliferation relationship: positively_regulates GO:1990863 ! acinar cell proliferation created_by: sl creation_date: 2015-09-30T15:20:03Z [Term] id: GO:1904705 name: regulation of vascular associated smooth muscle cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of vascular smooth muscle cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:23246467] synonym: "regulation of vascular smooth muscle cell proliferation" EXACT [] synonym: "regulation of VSMC proliferation" EXACT [GOC:TermGenie] is_a: GO:0048660 ! regulation of smooth muscle cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1990874 ! vascular associated smooth muscle cell proliferation relationship: regulates GO:1990874 ! vascular associated smooth muscle cell proliferation created_by: sl creation_date: 2015-10-01T16:05:20Z [Term] id: GO:1904706 name: negative regulation of vascular associated smooth muscle cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:23246467] synonym: "down regulation of vascular smooth muscle cell proliferation" EXACT [GOC:TermGenie] synonym: "down regulation of VSMC proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of vascular smooth muscle cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of VSMC proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of vascular smooth muscle cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of VSMC proliferation" EXACT [GOC:TermGenie] synonym: "inhibition of vascular smooth muscle cell proliferation" NARROW [GOC:TermGenie] synonym: "inhibition of VSMC proliferation" NARROW [GOC:TermGenie] synonym: "negative regulation of vascular smooth muscle cell proliferation" EXACT [] synonym: "negative regulation of VSMC proliferation" EXACT [GOC:TermGenie] is_a: GO:0048662 ! negative regulation of smooth muscle cell proliferation is_a: GO:1904705 ! regulation of vascular associated smooth muscle cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1990874 ! vascular associated smooth muscle cell proliferation relationship: negatively_regulates GO:1990874 ! vascular associated smooth muscle cell proliferation created_by: sl creation_date: 2015-10-01T16:05:26Z [Term] id: GO:1904707 name: positive regulation of vascular associated smooth muscle cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:23246467] synonym: "activation of vascular smooth muscle cell proliferation" NARROW [GOC:TermGenie] synonym: "activation of VSMC proliferation" NARROW [GOC:TermGenie] synonym: "positive regulation of vascular smooth muscle cell proliferation" EXACT [] synonym: "positive regulation of VSMC proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of vascular smooth muscle cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of VSMC proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of vascular smooth muscle cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of VSMC proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of vascular smooth muscle cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of VSMC proliferation" EXACT [GOC:TermGenie] is_a: GO:0048661 ! positive regulation of smooth muscle cell proliferation is_a: GO:1904705 ! regulation of vascular associated smooth muscle cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1990874 ! vascular associated smooth muscle cell proliferation relationship: positively_regulates GO:1990874 ! vascular associated smooth muscle cell proliferation created_by: sl creation_date: 2015-10-01T16:05:32Z [Term] id: GO:1904738 name: vascular associated smooth muscle cell migration namespace: biological_process def: "The orderly movement of a vascular associated smooth muscle cell from one site to another." [GO_REF:0000091, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:20693317] synonym: "vascular smooth muscle cell migration" EXACT [] is_a: GO:0014909 ! smooth muscle cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000359 ! vascular associated smooth muscle cell relationship: results_in_movement_of CL:0000359 ! vascular associated smooth muscle cell created_by: rph creation_date: 2015-10-15T09:56:00Z [Term] id: GO:1904746 name: negative regulation of apoptotic process involved in development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in development." [GO_REF:0000058, GOC:TermGenie, PMID:22801495] comment: U4PR86 in PMID:22801495 inferred from mutant phenotype synonym: "down regulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "down regulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "down regulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "down regulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "down regulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "down regulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "down regulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "down regulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "down regulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic process involved in development" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "down regulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "down regulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "down regulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "down regulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "down regulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "down regulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "down regulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "down regulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "down regulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "down regulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "down regulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "down regulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "down regulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "down regulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "down-regulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "down-regulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "down-regulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "down-regulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic process involved in development" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "down-regulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "down-regulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "down-regulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "down-regulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "down-regulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "down-regulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "down-regulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "down-regulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "down-regulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "down-regulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "down-regulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "down-regulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "downregulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "downregulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "downregulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "downregulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "downregulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "downregulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "downregulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "downregulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "downregulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic process involved in development" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "downregulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "downregulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "downregulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "downregulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "downregulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "downregulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "downregulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "downregulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "downregulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "downregulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "downregulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "downregulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "downregulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "downregulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "inhibition of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "inhibition of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "inhibition of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "inhibition of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "inhibition of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "inhibition of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic process involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic process involved in development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic process involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "inhibition of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "inhibition of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "inhibition of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "inhibition of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "inhibition of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "inhibition of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "inhibition of programmed cell death by apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "inhibition of programmed cell death by apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "inhibition of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "inhibition of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "inhibition of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "inhibition of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "negative regulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "negative regulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "negative regulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "negative regulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "negative regulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "negative regulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "negative regulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "negative regulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "negative regulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "negative regulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "negative regulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "negative regulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "negative regulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "negative regulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "negative regulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "negative regulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "negative regulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "negative regulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "negative regulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "negative regulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "negative regulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "negative regulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "negative regulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "negative regulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "negative regulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "negative regulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "negative regulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "negative regulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] is_a: GO:0043066 ! negative regulation of apoptotic process is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:1904748 ! regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1902742 ! apoptotic process involved in development relationship: negatively_regulates GO:1902742 ! apoptotic process involved in development created_by: es creation_date: 2015-10-19T14:12:27Z [Term] id: GO:1904747 name: positive regulation of apoptotic process involved in development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in development." [GO_REF:0000058, GOC:TermGenie, PMID:22801495] comment: U4PR86 in PMID:22801495 inferred from mutant phenotype synonym: "activation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "activation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "activation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "activation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "activation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "activation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "activation of apoptotic cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "activation of apoptotic cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "activation of apoptotic process involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "activation of apoptotic process involved in development" NARROW [GOC:TermGenie] synonym: "activation of apoptotic process involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "activation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "activation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "activation of apoptotic programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "activation of apoptotic programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "activation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "activation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "activation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "activation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "activation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "activation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "activation of programmed cell death by apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "activation of programmed cell death by apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "activation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "activation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "activation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "activation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "positive regulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "positive regulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "positive regulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "positive regulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "positive regulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "positive regulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "positive regulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "positive regulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "positive regulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "positive regulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "positive regulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "positive regulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "positive regulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "positive regulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "positive regulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "positive regulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "positive regulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "positive regulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "positive regulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "positive regulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "positive regulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "positive regulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "positive regulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "positive regulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "positive regulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "positive regulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "positive regulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "positive regulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "up regulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "up regulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "up regulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "up regulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "up regulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "up regulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "up regulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "up regulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "up regulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic process involved in development" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "up regulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "up regulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "up regulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "up regulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "up regulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "up regulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "up regulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "up regulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "up regulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "up regulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "up regulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "up regulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "up regulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "up regulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "up-regulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "up-regulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "up-regulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "up-regulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic process involved in development" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "up-regulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "up-regulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "up-regulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "up-regulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "up-regulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "up-regulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "up-regulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "up-regulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "up-regulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "up-regulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "up-regulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "up-regulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "upregulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "upregulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "upregulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "upregulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "upregulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "upregulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "upregulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "upregulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "upregulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic process involved in development" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "upregulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "upregulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "upregulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "upregulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "upregulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "upregulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "upregulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "upregulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "upregulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "upregulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "upregulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "upregulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "upregulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "upregulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] is_a: GO:0043065 ! positive regulation of apoptotic process is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:1904748 ! regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1902742 ! apoptotic process involved in development relationship: positively_regulates GO:1902742 ! apoptotic process involved in development created_by: es creation_date: 2015-10-19T14:12:34Z [Term] id: GO:1904748 name: regulation of apoptotic process involved in development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of apoptotic process involved in development." [GO_REF:0000058, GOC:TermGenie, PMID:22801495] comment: Q10943 in PMID:22801495, inferred from mutant phenotype synonym: "regulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "regulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "regulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "regulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "regulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "regulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "regulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "regulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "regulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "regulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "regulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "regulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "regulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "regulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "regulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "regulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "regulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "regulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "regulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "regulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "regulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "regulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "regulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "regulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "regulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "regulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "regulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "regulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] is_a: GO:0042981 ! regulation of apoptotic process is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1902742 ! apoptotic process involved in development relationship: regulates GO:1902742 ! apoptotic process involved in development created_by: es creation_date: 2015-10-19T15:02:28Z [Term] id: GO:1904749 name: regulation of protein localization to nucleolus namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein localization to nucleolus." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:24415760] synonym: "regulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] synonym: "regulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] synonym: "regulation of protein localization in nucleolus" EXACT [GOC:TermGenie] is_a: GO:1900180 ! regulation of protein localization to nucleus intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1902570 ! protein localization to nucleolus relationship: regulates GO:1902570 ! protein localization to nucleolus created_by: nc creation_date: 2015-10-19T15:16:17Z [Term] id: GO:1904750 name: negative regulation of protein localization to nucleolus namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleolus." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:24415760] synonym: "down regulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] synonym: "down regulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization in nucleolus" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization to nucleolus" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization in nucleolus" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to nucleolus" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization in nucleolus" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to nucleolus" EXACT [GOC:TermGenie] synonym: "inhibition of protein localisation in nucleolus" NARROW [GOC:TermGenie] synonym: "inhibition of protein localisation to nucleolus" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization in nucleolus" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization to nucleolus" NARROW [GOC:TermGenie] synonym: "negative regulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localization in nucleolus" EXACT [GOC:TermGenie] is_a: GO:1900181 ! negative regulation of protein localization to nucleus is_a: GO:1904749 ! regulation of protein localization to nucleolus intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1902570 ! protein localization to nucleolus relationship: negatively_regulates GO:1902570 ! protein localization to nucleolus created_by: nc creation_date: 2015-10-19T15:16:24Z [Term] id: GO:1904751 name: positive regulation of protein localization to nucleolus namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein localization to nucleolus." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:24415760] synonym: "activation of protein localisation in nucleolus" NARROW [GOC:TermGenie] synonym: "activation of protein localisation to nucleolus" NARROW [GOC:TermGenie] synonym: "activation of protein localization in nucleolus" NARROW [GOC:TermGenie] synonym: "activation of protein localization to nucleolus" NARROW [GOC:TermGenie] synonym: "positive regulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localization in nucleolus" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization in nucleolus" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization to nucleolus" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization in nucleolus" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to nucleolus" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization in nucleolus" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to nucleolus" EXACT [GOC:TermGenie] is_a: GO:1900182 ! positive regulation of protein localization to nucleus is_a: GO:1904749 ! regulation of protein localization to nucleolus intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1902570 ! protein localization to nucleolus relationship: positively_regulates GO:1902570 ! protein localization to nucleolus created_by: nc creation_date: 2015-10-19T15:16:30Z [Term] id: GO:1904752 name: regulation of vascular associated smooth muscle cell migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell migration." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:20693317] synonym: "regulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] is_a: GO:0014910 ! regulation of smooth muscle cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1904738 ! vascular associated smooth muscle cell migration relationship: regulates GO:1904738 ! vascular associated smooth muscle cell migration created_by: rph creation_date: 2015-10-19T15:49:52Z [Term] id: GO:1904753 name: negative regulation of vascular associated smooth muscle cell migration namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell migration." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:20693317] synonym: "down regulation of vascular associated smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "down regulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "down-regulation of vascular associated smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "down-regulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "downregulation of vascular associated smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "downregulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "inhibition of vascular associated smooth muscle cell migration" NARROW [GOC:TermGenie] synonym: "inhibition of vascular smooth muscle cell migration" NARROW [GOC:TermGenie] synonym: "negative regulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] is_a: GO:0014912 ! negative regulation of smooth muscle cell migration is_a: GO:1904752 ! regulation of vascular associated smooth muscle cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1904738 ! vascular associated smooth muscle cell migration relationship: negatively_regulates GO:1904738 ! vascular associated smooth muscle cell migration created_by: rph creation_date: 2015-10-19T15:49:58Z [Term] id: GO:1904754 name: positive regulation of vascular associated smooth muscle cell migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell migration." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:20693317] synonym: "activation of vascular associated smooth muscle cell migration" NARROW [GOC:TermGenie] synonym: "activation of vascular smooth muscle cell migration" NARROW [GOC:TermGenie] synonym: "positive regulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "up regulation of vascular associated smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "up regulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "up-regulation of vascular associated smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "up-regulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "upregulation of vascular associated smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "upregulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] is_a: GO:0014911 ! positive regulation of smooth muscle cell migration is_a: GO:1904752 ! regulation of vascular associated smooth muscle cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1904738 ! vascular associated smooth muscle cell migration relationship: positively_regulates GO:1904738 ! vascular associated smooth muscle cell migration created_by: rph creation_date: 2015-10-19T15:50:05Z [Term] id: GO:1904770 name: intramembranous bone morphogenesis namespace: biological_process def: "The developmental process by which an intramembranous bone is generated and organized." [GO_REF:0000083, GOC:TermGenie, PMID:26399686] synonym: "intramembranous bones morphogenesis" RELATED [GOC:TermGenie] synonym: "membrane bone morphogenesis" RELATED [GOC:TermGenie] is_a: GO:0060349 ! bone morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002514 ! intramembranous bone relationship: results_in_morphogenesis_of UBERON:0002514 ! intramembranous bone created_by: dos creation_date: 2015-10-28T11:46:04Z [Term] id: GO:1904776 name: regulation of protein localization to cell cortex namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein localization to cell cortex." [GO_REF:0000058, GOC:TermGenie, PMID:17115027] comment: An example is cye-1 in C. elegans, UniProt ID O01501 in PMID:17115027. synonym: "regulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] is_a: GO:1904375 ! regulation of protein localization to cell periphery intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0072697 ! protein localization to cell cortex relationship: regulates GO:0072697 ! protein localization to cell cortex created_by: es creation_date: 2015-10-29T16:55:01Z [Term] id: GO:1904777 name: negative regulation of protein localization to cell cortex namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell cortex." [GO_REF:0000058, GOC:TermGenie, PMID:17115027] comment: An example is cye-1 in C. elegans, UniProt ID O01501 in PMID:17115027. synonym: "down regulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization to cell cortex" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to cell cortex" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to cell cortex" EXACT [GOC:TermGenie] synonym: "inhibition of protein localisation to cell cortex" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization to cell cortex" NARROW [GOC:TermGenie] synonym: "negative regulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] is_a: GO:1904376 ! negative regulation of protein localization to cell periphery is_a: GO:1904776 ! regulation of protein localization to cell cortex intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0072697 ! protein localization to cell cortex relationship: negatively_regulates GO:0072697 ! protein localization to cell cortex created_by: es creation_date: 2015-10-29T16:55:08Z [Term] id: GO:1904778 name: positive regulation of protein localization to cell cortex namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein localization to cell cortex." [GO_REF:0000058, GOC:TermGenie, PMID:17115027] comment: An example is cye-1 in C. elegans, UniProt ID O01501 in PMID:17115027. synonym: "activation of protein localisation to cell cortex" NARROW [GOC:TermGenie] synonym: "activation of protein localization to cell cortex" NARROW [GOC:TermGenie] synonym: "positive regulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization to cell cortex" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to cell cortex" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to cell cortex" EXACT [GOC:TermGenie] is_a: GO:1904377 ! positive regulation of protein localization to cell periphery is_a: GO:1904776 ! regulation of protein localization to cell cortex intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0072697 ! protein localization to cell cortex relationship: positively_regulates GO:0072697 ! protein localization to cell cortex created_by: es creation_date: 2015-10-29T16:55:15Z [Term] id: GO:1904817 name: serous membrane development namespace: biological_process def: "The process whose specific outcome is the progression of a serous membrane over time, from its formation to the mature structure." [GO_REF:0000094, GOC:dph, GOC:TermGenie, PMID:15840053] synonym: "serosa development" RELATED [GOC:TermGenie] synonym: "tunica serosa development" EXACT [GOC:TermGenie] synonym: "wall of serous sac development" EXACT [GOC:TermGenie] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000042 ! serous membrane relationship: results_in_development_of UBERON:0000042 ! serous membrane created_by: dph creation_date: 2015-11-17T19:00:01Z [Term] id: GO:1904818 name: visceral peritoneum development namespace: biological_process def: "The process whose specific outcome is the progression of a visceral peritoneum over time, from its formation to the mature structure." [GO_REF:0000094, GOC:dph, GOC:TermGenie, PMID:15840053] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001178 ! visceral peritoneum relationship: part_of GO:1904820 ! peritoneum development relationship: results_in_development_of UBERON:0001178 ! visceral peritoneum created_by: dph creation_date: 2015-11-17T19:00:17Z [Term] id: GO:1904819 name: parietal peritoneum development namespace: biological_process def: "The process whose specific outcome is the progression of a parietal peritoneum over time, from its formation to the mature structure." [GO_REF:0000094, GOC:dph, GOC:TermGenie, PMID:15840053] synonym: "peritoneal cavity lining development" EXACT [GOC:TermGenie] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001366 ! parietal peritoneum relationship: part_of GO:1904820 ! peritoneum development relationship: results_in_development_of UBERON:0001366 ! parietal peritoneum created_by: dph creation_date: 2015-11-17T19:00:24Z [Term] id: GO:1904820 name: peritoneum development namespace: biological_process def: "The process whose specific outcome is the progression of a peritoneum over time, from its formation to the mature structure." [GO_REF:0000094, GOC:dph, GOC:TermGenie, PMID:15840053] synonym: "peritonaeum development" RELATED [GOC:TermGenie] is_a: GO:1904817 ! serous membrane development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002358 ! peritoneum relationship: results_in_development_of UBERON:0002358 ! peritoneum created_by: dph creation_date: 2015-11-18T17:23:51Z [Term] id: GO:1904829 name: regulation of aortic smooth muscle cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of aortic smooth muscle cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22034194] is_a: GO:1905063 ! regulation of vascular associated smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0035887 ! aortic smooth muscle cell differentiation relationship: regulates GO:0035887 ! aortic smooth muscle cell differentiation created_by: rph creation_date: 2015-11-24T10:20:40Z [Term] id: GO:1904830 name: negative regulation of aortic smooth muscle cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of aortic smooth muscle cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22034194] synonym: "down regulation of aortic smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of aortic smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of aortic smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of aortic smooth muscle cell differentiation" NARROW [GOC:TermGenie] is_a: GO:1904829 ! regulation of aortic smooth muscle cell differentiation is_a: GO:1905064 ! negative regulation of vascular associated smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0035887 ! aortic smooth muscle cell differentiation relationship: negatively_regulates GO:0035887 ! aortic smooth muscle cell differentiation created_by: rph creation_date: 2015-11-24T10:20:47Z [Term] id: GO:1904831 name: positive regulation of aortic smooth muscle cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of aortic smooth muscle cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22034194] synonym: "activation of aortic smooth muscle cell differentiation" NARROW [GOC:TermGenie] synonym: "up regulation of aortic smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of aortic smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of aortic smooth muscle cell differentiation" EXACT [GOC:TermGenie] is_a: GO:1904829 ! regulation of aortic smooth muscle cell differentiation is_a: GO:1905065 ! positive regulation of vascular associated smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0035887 ! aortic smooth muscle cell differentiation relationship: positively_regulates GO:0035887 ! aortic smooth muscle cell differentiation created_by: rph creation_date: 2015-11-24T10:20:54Z [Term] id: GO:1904888 name: cranial skeletal system development namespace: biological_process def: "The process whose specific outcome is the progression of a cranial skeletal system over time, from its formation to the mature structure. The cranial skeletal system is the skeletal subdivision of the head, and includes the skull (cranium plus mandible), pharyngeal and/or hyoid apparatus." [GO_REF:0000094, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:11262227] synonym: "cranial skeleton development" NARROW [GOC:TermGenie] synonym: "craniofacial development" NARROW [PMID:11262227] synonym: "cranium development" RELATED [GOC:TermGenie] synonym: "osteocranium development" NARROW [GOC:TermGenie] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0010323 ! cranial skeletal system relationship: results_in_development_of UBERON:0010323 ! cranial skeletal system created_by: bf creation_date: 2016-01-07T13:45:06Z [Term] id: GO:1904933 name: regulation of cell proliferation in midbrain namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell proliferation in midbrain." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:18953410, PMID:24431302] synonym: "regulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] synonym: "regulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] is_a: GO:2000177 ! regulation of neural precursor cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0033278 ! cell proliferation in midbrain relationship: regulates GO:0033278 ! cell proliferation in midbrain created_by: bf creation_date: 2016-02-01T13:16:11Z [Term] id: GO:1904934 name: negative regulation of cell proliferation in midbrain namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in midbrain." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:18953410, PMID:24431302] synonym: "down regulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] synonym: "down regulation of cell proliferation in midbrain" EXACT [GOC:TermGenie] synonym: "down regulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] synonym: "down-regulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] synonym: "down-regulation of cell proliferation in midbrain" EXACT [GOC:TermGenie] synonym: "down-regulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] synonym: "downregulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] synonym: "downregulation of cell proliferation in midbrain" EXACT [GOC:TermGenie] synonym: "downregulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] synonym: "inhibition of cell proliferation in mesencephalon" NARROW [GOC:TermGenie] synonym: "inhibition of cell proliferation in midbrain" NARROW [GOC:TermGenie] synonym: "inhibition of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] synonym: "negative regulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] synonym: "negative regulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] is_a: GO:1904933 ! regulation of cell proliferation in midbrain is_a: GO:2000178 ! negative regulation of neural precursor cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0033278 ! cell proliferation in midbrain relationship: negatively_regulates GO:0033278 ! cell proliferation in midbrain created_by: bf creation_date: 2016-02-01T13:16:19Z [Term] id: GO:1904935 name: positive regulation of cell proliferation in midbrain namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell proliferation in midbrain." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24431302] synonym: "activation of cell proliferation in mesencephalon" NARROW [GOC:TermGenie] synonym: "activation of cell proliferation in midbrain" NARROW [GOC:TermGenie] synonym: "activation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] synonym: "positive regulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] synonym: "positive regulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] synonym: "up regulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] synonym: "up regulation of cell proliferation in midbrain" EXACT [GOC:TermGenie] synonym: "up regulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] synonym: "up-regulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] synonym: "up-regulation of cell proliferation in midbrain" EXACT [GOC:TermGenie] synonym: "up-regulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] synonym: "upregulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] synonym: "upregulation of cell proliferation in midbrain" EXACT [GOC:TermGenie] synonym: "upregulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] is_a: GO:1904933 ! regulation of cell proliferation in midbrain is_a: GO:2000179 ! positive regulation of neural precursor cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0033278 ! cell proliferation in midbrain relationship: positively_regulates GO:0033278 ! cell proliferation in midbrain created_by: bf creation_date: 2016-02-01T13:16:27Z [Term] id: GO:1904936 name: interneuron migration namespace: biological_process def: "The orderly movement of an interneuron from one site to another." [GO_REF:0000091, GOC:ah, GOC:TermGenie, PMID:18622031] synonym: "inter neuron migration" EXACT [GOC:ah] synonym: "inter-neuron migration" EXACT [GOC:ah] is_a: GO:0001764 ! neuron migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000099 ! interneuron relationship: results_in_movement_of CL:0000099 ! interneuron created_by: ah creation_date: 2016-02-01T14:04:32Z [Term] id: GO:1904937 name: sensory neuron migration namespace: biological_process def: "The orderly movement of a sensory neuron from one site to another." [GO_REF:0000091, GOC:ah, GOC:TermGenie, PMID:18622031] is_a: GO:0001764 ! neuron migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000101 ! sensory neuron relationship: results_in_movement_of CL:0000101 ! sensory neuron created_by: ah creation_date: 2016-02-01T14:15:50Z [Term] id: GO:1904942 name: regulation of cardiac ventricle formation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac ventricle formation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23575307] is_a: GO:1901210 ! regulation of cardiac chamber formation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003211 ! cardiac ventricle formation relationship: regulates GO:0003211 ! cardiac ventricle formation created_by: bc creation_date: 2016-02-02T16:37:16Z [Term] id: GO:1904943 name: negative regulation of cardiac ventricle formation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle formation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23575307] synonym: "down regulation of cardiac ventricle formation" EXACT [GOC:TermGenie] synonym: "down-regulation of cardiac ventricle formation" EXACT [GOC:TermGenie] synonym: "downregulation of cardiac ventricle formation" EXACT [GOC:TermGenie] synonym: "inhibition of cardiac ventricle formation" NARROW [GOC:TermGenie] is_a: GO:1901211 ! negative regulation of cardiac chamber formation is_a: GO:1904413 ! negative regulation of cardiac ventricle development is_a: GO:1904942 ! regulation of cardiac ventricle formation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0003211 ! cardiac ventricle formation relationship: negatively_regulates GO:0003211 ! cardiac ventricle formation created_by: bc creation_date: 2016-02-02T16:37:24Z [Term] id: GO:1904944 name: positive regulation of cardiac ventricle formation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cardiac ventricle formation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23575307] synonym: "activation of cardiac ventricle formation" NARROW [GOC:TermGenie] synonym: "up regulation of cardiac ventricle formation" EXACT [GOC:TermGenie] synonym: "up-regulation of cardiac ventricle formation" EXACT [GOC:TermGenie] synonym: "upregulation of cardiac ventricle formation" EXACT [GOC:TermGenie] is_a: GO:1901212 ! positive regulation of cardiac chamber formation is_a: GO:1904942 ! regulation of cardiac ventricle formation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0003211 ! cardiac ventricle formation relationship: positively_regulates GO:0003211 ! cardiac ventricle formation created_by: bc creation_date: 2016-02-02T16:37:31Z [Term] id: GO:1904950 name: negative regulation of establishment of protein localization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization." [GO_REF:0000058, GOC:TermGenie, PMID:22761445] synonym: "down regulation of establishment of protein localisation" EXACT [GOC:TermGenie] synonym: "down regulation of establishment of protein localization" EXACT [GOC:TermGenie] synonym: "down regulation of protein positioning" EXACT [GOC:TermGenie] synonym: "down regulation of protein recruitment" EXACT [GOC:TermGenie] synonym: "down-regulation of establishment of protein localisation" EXACT [GOC:TermGenie] synonym: "down-regulation of establishment of protein localization" EXACT [GOC:TermGenie] synonym: "down-regulation of protein positioning" EXACT [GOC:TermGenie] synonym: "down-regulation of protein recruitment" EXACT [GOC:TermGenie] synonym: "downregulation of establishment of protein localisation" EXACT [GOC:TermGenie] synonym: "downregulation of establishment of protein localization" EXACT [GOC:TermGenie] synonym: "downregulation of protein positioning" EXACT [GOC:TermGenie] synonym: "downregulation of protein recruitment" EXACT [GOC:TermGenie] synonym: "inhibition of establishment of protein localisation" NARROW [GOC:TermGenie] synonym: "inhibition of establishment of protein localization" NARROW [GOC:TermGenie] synonym: "inhibition of protein positioning" NARROW [GOC:TermGenie] synonym: "inhibition of protein recruitment" NARROW [GOC:TermGenie] synonym: "negative regulation of establishment of protein localisation" EXACT [GOC:TermGenie] synonym: "negative regulation of protein positioning" EXACT [GOC:TermGenie] synonym: "negative regulation of protein recruitment" EXACT [GOC:TermGenie] is_a: GO:0048519 ! negative regulation of biological process is_a: GO:0070201 ! regulation of establishment of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0045184 ! establishment of protein localization relationship: negatively_regulates GO:0045184 ! establishment of protein localization created_by: mec creation_date: 2016-02-05T09:59:24Z [Term] id: GO:1904951 name: positive regulation of establishment of protein localization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of establishment of protein localization." [GO_REF:0000058, GOC:TermGenie, PMID:22761445] synonym: "activation of establishment of protein localisation" NARROW [GOC:TermGenie] synonym: "activation of establishment of protein localization" NARROW [GOC:TermGenie] synonym: "activation of protein positioning" NARROW [GOC:TermGenie] synonym: "activation of protein recruitment" NARROW [GOC:TermGenie] synonym: "positive regulation of establishment of protein localisation" EXACT [GOC:TermGenie] synonym: "positive regulation of protein positioning" EXACT [GOC:TermGenie] synonym: "positive regulation of protein recruitment" EXACT [GOC:TermGenie] synonym: "up regulation of establishment of protein localisation" EXACT [GOC:TermGenie] synonym: "up regulation of establishment of protein localization" EXACT [GOC:TermGenie] synonym: "up regulation of protein positioning" EXACT [GOC:TermGenie] synonym: "up regulation of protein recruitment" EXACT [GOC:TermGenie] synonym: "up-regulation of establishment of protein localisation" EXACT [GOC:TermGenie] synonym: "up-regulation of establishment of protein localization" EXACT [GOC:TermGenie] synonym: "up-regulation of protein positioning" EXACT [GOC:TermGenie] synonym: "up-regulation of protein recruitment" EXACT [GOC:TermGenie] synonym: "upregulation of establishment of protein localisation" EXACT [GOC:TermGenie] synonym: "upregulation of establishment of protein localization" EXACT [GOC:TermGenie] synonym: "upregulation of protein positioning" EXACT [GOC:TermGenie] synonym: "upregulation of protein recruitment" EXACT [GOC:TermGenie] is_a: GO:0048518 ! positive regulation of biological process is_a: GO:0070201 ! regulation of establishment of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0045184 ! establishment of protein localization relationship: positively_regulates GO:0045184 ! establishment of protein localization created_by: mec creation_date: 2016-02-05T09:59:32Z [Term] id: GO:1904987 name: regulation of endothelial cell activation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of endothelial cell activation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:24255059] is_a: GO:0050865 ! regulation of cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0042118 ! endothelial cell activation relationship: regulates GO:0042118 ! endothelial cell activation created_by: bc creation_date: 2016-02-29T16:16:09Z [Term] id: GO:1904988 name: negative regulation of endothelial cell activation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell activation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:24255059] synonym: "down regulation of endothelial cell activation" EXACT [GOC:TermGenie] synonym: "down-regulation of endothelial cell activation" EXACT [GOC:TermGenie] synonym: "downregulation of endothelial cell activation" EXACT [GOC:TermGenie] synonym: "inhibition of endothelial cell activation" NARROW [GOC:TermGenie] is_a: GO:0050866 ! negative regulation of cell activation is_a: GO:1904987 ! regulation of endothelial cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0042118 ! endothelial cell activation relationship: negatively_regulates GO:0042118 ! endothelial cell activation created_by: bc creation_date: 2016-02-29T16:16:18Z [Term] id: GO:1904989 name: positive regulation of endothelial cell activation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of endothelial cell activation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:24255059] synonym: "activation of endothelial cell activation" NARROW [GOC:TermGenie] synonym: "up regulation of endothelial cell activation" EXACT [GOC:TermGenie] synonym: "up-regulation of endothelial cell activation" EXACT [GOC:TermGenie] synonym: "upregulation of endothelial cell activation" EXACT [GOC:TermGenie] is_a: GO:0050867 ! positive regulation of cell activation is_a: GO:1904987 ! regulation of endothelial cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0042118 ! endothelial cell activation relationship: positively_regulates GO:0042118 ! endothelial cell activation created_by: bc creation_date: 2016-02-29T16:16:25Z [Term] id: GO:1905039 name: carboxylic acid transmembrane transport namespace: biological_process def: "The process in which carboxylic acid is transported across a membrane." [GO_REF:0000069, GOC:TermGenie, PMID:10869563] is_a: GO:0046942 ! carboxylic acid transport is_a: GO:0055085 ! transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:29067 ! carboxylic acid anion intersection_of: results_in_transport_across GO:0016020 ! membrane created_by: vw creation_date: 2016-03-09T15:33:53Z [Term] id: GO:1905063 name: regulation of vascular associated smooth muscle cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of vascular smooth muscle cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19088079] synonym: "regulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "regulation of VSMC differentiation" EXACT [GOC:TermGenie] is_a: GO:0051150 ! regulation of smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0035886 ! vascular associated smooth muscle cell differentiation relationship: regulates GO:0035886 ! vascular associated smooth muscle cell differentiation created_by: rph creation_date: 2016-03-21T11:14:53Z [Term] id: GO:1905064 name: negative regulation of vascular associated smooth muscle cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19088079] synonym: "down regulation of vascular associated smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of VSMC differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of vascular associated smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of VSMC differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of vascular associated smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of VSMC differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of vascular associated smooth muscle cell differentiation" NARROW [GOC:TermGenie] synonym: "inhibition of vascular smooth muscle cell differentiation" NARROW [GOC:TermGenie] synonym: "inhibition of VSMC differentiation" NARROW [GOC:TermGenie] synonym: "negative regulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "negative regulation of VSMC differentiation" EXACT [GOC:TermGenie] is_a: GO:0051151 ! negative regulation of smooth muscle cell differentiation is_a: GO:1905063 ! regulation of vascular associated smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0035886 ! vascular associated smooth muscle cell differentiation relationship: negatively_regulates GO:0035886 ! vascular associated smooth muscle cell differentiation created_by: rph creation_date: 2016-03-21T11:15:03Z [Term] id: GO:1905065 name: positive regulation of vascular associated smooth muscle cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19088079] synonym: "activation of vascular associated smooth muscle cell differentiation" NARROW [GOC:TermGenie] synonym: "activation of vascular smooth muscle cell differentiation" NARROW [GOC:TermGenie] synonym: "activation of VSMC differentiation" NARROW [GOC:TermGenie] synonym: "positive regulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "positive regulation of VSMC differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of vascular associated smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of VSMC differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of vascular associated smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of VSMC differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of vascular associated smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of VSMC differentiation" EXACT [GOC:TermGenie] is_a: GO:0051152 ! positive regulation of smooth muscle cell differentiation is_a: GO:1905063 ! regulation of vascular associated smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0035886 ! vascular associated smooth muscle cell differentiation relationship: positively_regulates GO:0035886 ! vascular associated smooth muscle cell differentiation created_by: rph creation_date: 2016-03-21T11:15:13Z [Term] id: GO:1905069 name: allantois development namespace: biological_process def: "The process whose specific outcome is the progression of an allantois over time, from its formation to the mature structure." [GO_REF:0000094, GOC:TermGenie, PMID:17440924, PMID:21470579] synonym: "allantoic bud development" RELATED [GOC:TermGenie] is_a: GO:1903867 ! extraembryonic membrane development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004340 ! allantois relationship: results_in_development_of UBERON:0004340 ! allantois created_by: cls creation_date: 2016-03-21T15:18:21Z [Term] id: GO:1905126 name: regulation of axo-dendritic protein transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of axo-dendritic protein transport." [GO_REF:0000058, GOC:TermGenie, PMID:20694152] synonym: "regulation of axonal protein transport" NARROW [GOC:TermGenie] is_a: GO:0033157 ! regulation of intracellular protein transport is_a: GO:0060632 ! regulation of microtubule-based movement intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0099640 ! axo-dendritic protein transport relationship: regulates GO:0099640 ! axo-dendritic protein transport created_by: sl creation_date: 2016-04-11T20:38:31Z [Term] id: GO:1905127 name: negative regulation of axo-dendritic protein transport namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of axo-dendritic protein transport." [GO_REF:0000058, GOC:TermGenie, PMID:20694152] synonym: "down regulation of axo-dendritic protein transport" EXACT [GOC:TermGenie] synonym: "down regulation of axonal protein transport" NARROW [GOC:TermGenie] synonym: "down-regulation of axo-dendritic protein transport" EXACT [GOC:TermGenie] synonym: "down-regulation of axonal protein transport" NARROW [GOC:TermGenie] synonym: "downregulation of axo-dendritic protein transport" EXACT [GOC:TermGenie] synonym: "downregulation of axonal protein transport" NARROW [GOC:TermGenie] synonym: "inhibition of axo-dendritic protein transport" NARROW [GOC:TermGenie] synonym: "inhibition of axonal protein transport" NARROW [GOC:TermGenie] synonym: "negative regulation of axonal protein transport" NARROW [GOC:TermGenie] is_a: GO:0090317 ! negative regulation of intracellular protein transport is_a: GO:1905126 ! regulation of axo-dendritic protein transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0099640 ! axo-dendritic protein transport relationship: negatively_regulates GO:0099640 ! axo-dendritic protein transport created_by: sl creation_date: 2016-04-11T20:38:40Z [Term] id: GO:1905128 name: positive regulation of axo-dendritic protein transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of axo-dendritic protein transport." [GO_REF:0000058, GOC:TermGenie, PMID:20694152] synonym: "activation of axo-dendritic protein transport" NARROW [GOC:TermGenie] synonym: "activation of axonal protein transport" NARROW [GOC:TermGenie] synonym: "positive regulation of axonal protein transport" NARROW [GOC:TermGenie] synonym: "up regulation of axo-dendritic protein transport" EXACT [GOC:TermGenie] synonym: "up regulation of axonal protein transport" NARROW [GOC:TermGenie] synonym: "up-regulation of axo-dendritic protein transport" EXACT [GOC:TermGenie] synonym: "up-regulation of axonal protein transport" NARROW [GOC:TermGenie] synonym: "upregulation of axo-dendritic protein transport" EXACT [GOC:TermGenie] synonym: "upregulation of axonal protein transport" NARROW [GOC:TermGenie] is_a: GO:0090316 ! positive regulation of intracellular protein transport is_a: GO:1905126 ! regulation of axo-dendritic protein transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0099640 ! axo-dendritic protein transport relationship: positively_regulates GO:0099640 ! axo-dendritic protein transport created_by: sl creation_date: 2016-04-11T20:38:48Z [Term] id: GO:1905139 name: apical ectodermal ridge formation namespace: biological_process def: "The process that gives rise to the apical ectodermal ridge. This process pertains to the initial formation of a structure from unspecified parts." [GO_REF:0000081, GOC:TermGenie, PMID:18359901, PMID:9323126, PMID:9596583] synonym: "AER formation" RELATED [GOC:TermGenie] synonym: "apical epidermal ridge formation" EXACT [GOC:TermGenie] synonym: "crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of_anatomical_entity UBERON:0004356 ! apical ectodermal ridge relationship: part_of GO:0035107 ! appendage morphogenesis relationship: results_in_formation_of_anatomical_entity UBERON:0004356 ! apical ectodermal ridge created_by: dph creation_date: 2016-04-13T11:46:40Z [Term] id: GO:1905140 name: regulation of apical ectodermal ridge formation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of apical ectodermal ridge formation." [GO_REF:0000058, GOC:TermGenie, PMID:18359901] synonym: "regulation of AER formation" RELATED [GOC:TermGenie] synonym: "regulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] synonym: "regulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1905139 ! apical ectodermal ridge formation relationship: regulates GO:1905139 ! apical ectodermal ridge formation created_by: dph creation_date: 2016-04-13T12:16:40Z [Term] id: GO:1905141 name: negative regulation of apical ectodermal ridge formation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of apical ectodermal ridge formation." [GO_REF:0000058, GOC:TermGenie, PMID:18359901] synonym: "down regulation of AER formation" RELATED [GOC:TermGenie] synonym: "down regulation of apical ectodermal ridge formation" EXACT [GOC:TermGenie] synonym: "down regulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] synonym: "down regulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] synonym: "down-regulation of AER formation" RELATED [GOC:TermGenie] synonym: "down-regulation of apical ectodermal ridge formation" EXACT [GOC:TermGenie] synonym: "down-regulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] synonym: "down-regulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] synonym: "downregulation of AER formation" RELATED [GOC:TermGenie] synonym: "downregulation of apical ectodermal ridge formation" EXACT [GOC:TermGenie] synonym: "downregulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] synonym: "downregulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] synonym: "inhibition of AER formation" RELATED [GOC:TermGenie] synonym: "inhibition of apical ectodermal ridge formation" NARROW [GOC:TermGenie] synonym: "inhibition of apical epidermal ridge formation" NARROW [GOC:TermGenie] synonym: "inhibition of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] synonym: "negative regulation of AER formation" RELATED [GOC:TermGenie] synonym: "negative regulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] synonym: "negative regulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1905140 ! regulation of apical ectodermal ridge formation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1905139 ! apical ectodermal ridge formation relationship: negatively_regulates GO:1905139 ! apical ectodermal ridge formation created_by: dph creation_date: 2016-04-13T12:16:48Z [Term] id: GO:1905142 name: positive regulation of apical ectodermal ridge formation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of apical ectodermal ridge formation." [GO_REF:0000058, GOC:TermGenie, PMID:18359901] synonym: "activation of AER formation" RELATED [GOC:TermGenie] synonym: "positive regulation of AER formation" RELATED [GOC:TermGenie] synonym: "positive regulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] synonym: "positive regulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] synonym: "up regulation of AER formation" RELATED [GOC:TermGenie] synonym: "up regulation of apical ectodermal ridge formation" EXACT [GOC:TermGenie] synonym: "up regulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] synonym: "up regulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] synonym: "up-regulation of AER formation" RELATED [GOC:TermGenie] synonym: "up-regulation of apical ectodermal ridge formation" EXACT [GOC:TermGenie] synonym: "up-regulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] synonym: "up-regulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] synonym: "upregulation of AER formation" RELATED [GOC:TermGenie] synonym: "upregulation of apical ectodermal ridge formation" EXACT [GOC:TermGenie] synonym: "upregulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] synonym: "upregulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1905140 ! regulation of apical ectodermal ridge formation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1905139 ! apical ectodermal ridge formation relationship: positively_regulates GO:1905139 ! apical ectodermal ridge formation created_by: dph creation_date: 2016-04-13T12:16:57Z [Term] id: GO:1905144 name: response to acetylcholine namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:21238497] is_a: GO:0010033 ! response to organic substance is_a: GO:1901698 ! response to nitrogen compound is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus intersection_of: has_primary_input CHEBI:15355 ! acetylcholine relationship: has_primary_input CHEBI:15355 ! acetylcholine created_by: dos creation_date: 2016-04-14T08:54:49Z [Term] id: GO:1905147 name: regulation of smooth muscle hypertrophy namespace: biological_process def: "Any process that modulates the frequency, rate or extent of smooth muscle hypertrophy." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:22161164] is_a: GO:0014743 ! regulation of muscle hypertrophy is_a: GO:0043502 ! regulation of muscle adaptation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0014895 ! smooth muscle hypertrophy relationship: regulates GO:0014895 ! smooth muscle hypertrophy created_by: bc creation_date: 2016-04-15T12:47:07Z [Term] id: GO:1905148 name: negative regulation of smooth muscle hypertrophy namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle hypertrophy." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:22161164] synonym: "down regulation of smooth muscle hypertrophy" EXACT [GOC:TermGenie] synonym: "down-regulation of smooth muscle hypertrophy" EXACT [GOC:TermGenie] synonym: "downregulation of smooth muscle hypertrophy" EXACT [GOC:TermGenie] synonym: "inhibition of smooth muscle hypertrophy" NARROW [GOC:TermGenie] is_a: GO:0014741 ! negative regulation of muscle hypertrophy is_a: GO:0014745 ! negative regulation of muscle adaptation is_a: GO:1905147 ! regulation of smooth muscle hypertrophy intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0014895 ! smooth muscle hypertrophy relationship: negatively_regulates GO:0014895 ! smooth muscle hypertrophy created_by: bc creation_date: 2016-04-15T12:47:16Z [Term] id: GO:1905149 name: positive regulation of smooth muscle hypertrophy namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of smooth muscle hypertrophy." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:22161164] synonym: "activation of smooth muscle hypertrophy" NARROW [GOC:TermGenie] synonym: "up regulation of smooth muscle hypertrophy" EXACT [GOC:TermGenie] synonym: "up-regulation of smooth muscle hypertrophy" EXACT [GOC:TermGenie] synonym: "upregulation of smooth muscle hypertrophy" EXACT [GOC:TermGenie] is_a: GO:0014742 ! positive regulation of muscle hypertrophy is_a: GO:0014744 ! positive regulation of muscle adaptation is_a: GO:1905147 ! regulation of smooth muscle hypertrophy intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0014895 ! smooth muscle hypertrophy relationship: positively_regulates GO:0014895 ! smooth muscle hypertrophy created_by: bc creation_date: 2016-04-15T12:47:24Z [Term] id: GO:1905153 name: regulation of membrane invagination namespace: biological_process def: "Any process that modulates the frequency, rate or extent of membrane invagination." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:26589353] is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0010324 ! membrane invagination relationship: regulates GO:0010324 ! membrane invagination created_by: bf creation_date: 2016-04-18T15:43:54Z [Term] id: GO:1905154 name: negative regulation of membrane invagination namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of membrane invagination." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:26589353] synonym: "down regulation of membrane invagination" EXACT [GOC:TermGenie] synonym: "down-regulation of membrane invagination" EXACT [GOC:TermGenie] synonym: "downregulation of membrane invagination" EXACT [GOC:TermGenie] synonym: "inhibition of membrane invagination" NARROW [GOC:TermGenie] is_a: GO:0051129 ! negative regulation of cellular component organization is_a: GO:1905153 ! regulation of membrane invagination intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0010324 ! membrane invagination relationship: negatively_regulates GO:0010324 ! membrane invagination created_by: bf creation_date: 2016-04-18T15:44:04Z [Term] id: GO:1905155 name: positive regulation of membrane invagination namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of membrane invagination." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] synonym: "activation of membrane invagination" NARROW [GOC:TermGenie] synonym: "up regulation of membrane invagination" EXACT [GOC:TermGenie] synonym: "up-regulation of membrane invagination" EXACT [GOC:TermGenie] synonym: "upregulation of membrane invagination" EXACT [GOC:TermGenie] is_a: GO:0051130 ! positive regulation of cellular component organization is_a: GO:1905153 ! regulation of membrane invagination intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0010324 ! membrane invagination relationship: positively_regulates GO:0010324 ! membrane invagination created_by: bf creation_date: 2016-04-18T15:44:12Z [Term] id: GO:1905207 name: regulation of cardiocyte differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiocyte differentiation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23069713] synonym: "regulation of cardiac cell differentiation" EXACT [GOC:TermGenie] synonym: "regulation of heart cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0035051 ! cardiocyte differentiation relationship: regulates GO:0035051 ! cardiocyte differentiation created_by: bc creation_date: 2016-06-02T07:20:01Z [Term] id: GO:1905208 name: negative regulation of cardiocyte differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiocyte differentiation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23069713] synonym: "down regulation of cardiac cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of cardiocyte differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of heart cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of cardiac cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of cardiocyte differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of heart cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of cardiac cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of cardiocyte differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of heart cell differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of cardiac cell differentiation" NARROW [GOC:TermGenie] synonym: "inhibition of cardiocyte differentiation" NARROW [GOC:TermGenie] synonym: "inhibition of heart cell differentiation" NARROW [GOC:TermGenie] synonym: "negative regulation of cardiac cell differentiation" EXACT [GOC:TermGenie] synonym: "negative regulation of heart cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1905207 ! regulation of cardiocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0035051 ! cardiocyte differentiation relationship: negatively_regulates GO:0035051 ! cardiocyte differentiation created_by: bc creation_date: 2016-06-02T07:20:09Z [Term] id: GO:1905209 name: positive regulation of cardiocyte differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cardiocyte differentiation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23069713] synonym: "activation of cardiac cell differentiation" NARROW [GOC:TermGenie] synonym: "activation of cardiocyte differentiation" NARROW [GOC:TermGenie] synonym: "activation of heart cell differentiation" NARROW [GOC:TermGenie] synonym: "positive regulation of cardiac cell differentiation" EXACT [GOC:TermGenie] synonym: "positive regulation of heart cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of cardiac cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of cardiocyte differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of heart cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of cardiac cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of cardiocyte differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of heart cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of cardiac cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of cardiocyte differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of heart cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1905207 ! regulation of cardiocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0035051 ! cardiocyte differentiation relationship: positively_regulates GO:0035051 ! cardiocyte differentiation created_by: bc creation_date: 2016-06-02T07:20:16Z [Term] id: GO:1905213 name: negative regulation of mitotic chromosome condensation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic chromosome condensation." [GO_REF:0000058, GOC:TermGenie, PMID:23219725] is_a: GO:0010948 ! negative regulation of cell cycle process is_a: GO:1902340 ! negative regulation of chromosome condensation is_a: GO:1903379 ! regulation of mitotic chromosome condensation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007076 ! mitotic chromosome condensation relationship: negatively_regulates GO:0007076 ! mitotic chromosome condensation created_by: vw creation_date: 2016-06-03T08:41:08Z [Term] id: GO:1905223 name: epicardium morphogenesis namespace: biological_process def: "The developmental process by which an epicardium is generated and organized." [GO_REF:0000083, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:18718461] synonym: "heart epicardium morphogenesis" EXACT [GOC:TermGenie] synonym: "pericardium visceral mesothelium morphogenesis" RELATED [GOC:TermGenie] synonym: "visceral serous pericardium of heart morphogenesis" EXACT [GOC:TermGenie] synonym: "visceral serous pericardium proper morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002348 ! epicardium relationship: results_in_morphogenesis_of UBERON:0002348 ! epicardium created_by: rl creation_date: 2016-06-07T10:02:32Z [Term] id: GO:1905268 name: negative regulation of chromatin organization namespace: biological_process alt_id: GO:0045798 alt_id: GO:1903309 def: "Any process that stops, prevents or reduces the frequency, rate or extent of chromatin organization." [GO_REF:0000058, GOC:pr, GOC:TermGenie, GOC:vw, PMID:654321] synonym: "down regulation of chromatin assembly or disassembly" RELATED [] synonym: "down regulation of chromatin organisation" EXACT [GOC:TermGenie] synonym: "down regulation of chromatin organization" EXACT [GOC:TermGenie] synonym: "down regulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] synonym: "down-regulation of chromatin assembly or disassembly" RELATED [] synonym: "down-regulation of chromatin organisation" EXACT [GOC:TermGenie] synonym: "down-regulation of chromatin organization" EXACT [GOC:TermGenie] synonym: "down-regulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] synonym: "downregulation of chromatin assembly or disassembly" RELATED [] synonym: "downregulation of chromatin organisation" EXACT [GOC:TermGenie] synonym: "downregulation of chromatin organization" EXACT [GOC:TermGenie] synonym: "downregulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] synonym: "inhibition of chromatin assembly or disassembly" NARROW [] synonym: "inhibition of chromatin organisation" NARROW [GOC:TermGenie] synonym: "inhibition of chromatin organization" NARROW [GOC:TermGenie] synonym: "inhibition of establishment or maintenance of chromatin architecture" NARROW [GOC:TermGenie] synonym: "negative regulation of chromatin assembly or disassembly" RELATED [] synonym: "negative regulation of chromatin assembly/disassembly" EXACT [] synonym: "negative regulation of chromatin modification" RELATED [] synonym: "negative regulation of chromatin organisation" EXACT [GOC:TermGenie] synonym: "negative regulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] is_a: GO:0051129 ! negative regulation of cellular component organization is_a: GO:1902275 ! regulation of chromatin organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006325 ! chromatin organization relationship: negatively_regulates GO:0006325 ! chromatin organization property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22766" xsd:anyURI created_by: pr creation_date: 2016-06-15T20:14:47Z [Term] id: GO:1905269 name: positive regulation of chromatin organization namespace: biological_process alt_id: GO:0045799 alt_id: GO:1903310 def: "Any process that activates or increases the frequency, rate or extent of chromatin organization." [GO_REF:0000058, GOC:pr, GOC:TermGenie, GOC:vw, PMID:654321] synonym: "activation of chromatin assembly or disassembly" NARROW [] synonym: "activation of chromatin organisation" NARROW [GOC:TermGenie] synonym: "activation of chromatin organization" NARROW [GOC:TermGenie] synonym: "activation of establishment or maintenance of chromatin architecture" NARROW [GOC:TermGenie] synonym: "positive regulation of chromatin assembly or disassembly" RELATED [] synonym: "positive regulation of chromatin assembly/disassembly" RELATED [] synonym: "positive regulation of chromatin modification" RELATED [] synonym: "positive regulation of chromatin organisation" EXACT [GOC:TermGenie] synonym: "positive regulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] synonym: "stimulation of chromatin assembly or disassembly" NARROW [] synonym: "up regulation of chromatin assembly or disassembly" RELATED [] synonym: "up regulation of chromatin organisation" EXACT [GOC:TermGenie] synonym: "up regulation of chromatin organization" EXACT [GOC:TermGenie] synonym: "up regulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] synonym: "up-regulation of chromatin assembly or disassembly" RELATED [] synonym: "up-regulation of chromatin organisation" EXACT [GOC:TermGenie] synonym: "up-regulation of chromatin organization" EXACT [GOC:TermGenie] synonym: "up-regulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] synonym: "upregulation of chromatin assembly or disassembly" EXACT [] synonym: "upregulation of chromatin organisation" EXACT [GOC:TermGenie] synonym: "upregulation of chromatin organization" EXACT [GOC:TermGenie] synonym: "upregulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] is_a: GO:1902275 ! regulation of chromatin organization is_a: GO:2001252 ! positive regulation of chromosome organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006325 ! chromatin organization relationship: positively_regulates GO:0006325 ! chromatin organization property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22766" xsd:anyURI created_by: pr creation_date: 2016-06-15T20:14:56Z [Term] id: GO:1905276 name: regulation of epithelial tube formation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of epithelial tube formation." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:25745997] comment: An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay). is_a: GO:1905330 ! regulation of morphogenesis of an epithelium is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0072175 ! epithelial tube formation relationship: regulates GO:0072175 ! epithelial tube formation created_by: bhm creation_date: 2016-06-20T09:35:41Z [Term] id: GO:1905277 name: negative regulation of epithelial tube formation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of epithelial tube formation." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:25745997] comment: An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay). synonym: "down regulation of epithelial tube formation" EXACT [GOC:TermGenie] synonym: "down-regulation of epithelial tube formation" EXACT [GOC:TermGenie] synonym: "downregulation of epithelial tube formation" EXACT [GOC:TermGenie] synonym: "inhibition of epithelial tube formation" NARROW [GOC:TermGenie] is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1905276 ! regulation of epithelial tube formation is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0072175 ! epithelial tube formation relationship: negatively_regulates GO:0072175 ! epithelial tube formation created_by: bhm creation_date: 2016-06-20T09:35:49Z [Term] id: GO:1905278 name: positive regulation of epithelial tube formation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of epithelial tube formation." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:25745997] comment: An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay). synonym: "activation of epithelial tube formation" NARROW [GOC:TermGenie] synonym: "up regulation of epithelial tube formation" EXACT [GOC:TermGenie] synonym: "up-regulation of epithelial tube formation" EXACT [GOC:TermGenie] synonym: "upregulation of epithelial tube formation" EXACT [GOC:TermGenie] is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1905276 ! regulation of epithelial tube formation is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0072175 ! epithelial tube formation relationship: positively_regulates GO:0072175 ! epithelial tube formation created_by: bhm creation_date: 2016-06-20T09:35:57Z [Term] id: GO:1905288 name: vascular associated smooth muscle cell apoptotic process namespace: biological_process def: "Any apoptotic process in a vascular associated smooth muscle cell." [GO_REF:0000085, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:26493107] synonym: "vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "VSMC apoptosis" NARROW [GOC:TermGenie] synonym: "VSMC apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0034390 ! smooth muscle cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000359 ! vascular associated smooth muscle cell relationship: occurs_in CL:0000359 ! vascular associated smooth muscle cell created_by: rph creation_date: 2016-06-23T13:24:20Z [Term] id: GO:1905292 name: regulation of neural crest cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of neural crest cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:15073157] is_a: GO:2000736 ! regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0014033 ! neural crest cell differentiation relationship: regulates GO:0014033 ! neural crest cell differentiation created_by: rl creation_date: 2016-06-28T15:02:01Z [Term] id: GO:1905293 name: negative regulation of neural crest cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of neural crest cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:15073157] synonym: "down regulation of neural crest cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of neural crest cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of neural crest cell differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of neural crest cell differentiation" NARROW [GOC:TermGenie] is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1905292 ! regulation of neural crest cell differentiation is_a: GO:2000737 ! negative regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0014033 ! neural crest cell differentiation relationship: negatively_regulates GO:0014033 ! neural crest cell differentiation created_by: rl creation_date: 2016-06-28T15:02:09Z [Term] id: GO:1905294 name: positive regulation of neural crest cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of neural crest cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:15073157] synonym: "activation of neural crest cell differentiation" NARROW [GOC:TermGenie] synonym: "up regulation of neural crest cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of neural crest cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of neural crest cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1905292 ! regulation of neural crest cell differentiation is_a: GO:2000738 ! positive regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0014033 ! neural crest cell differentiation relationship: positively_regulates GO:0014033 ! neural crest cell differentiation created_by: rl creation_date: 2016-06-28T15:02:16Z [Term] id: GO:1905298 name: regulation of intestinal epithelial cell development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of intestinal epithelial cell development." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23904268] is_a: GO:0030856 ! regulation of epithelial cell differentiation is_a: GO:0060284 ! regulation of cell development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060576 ! intestinal epithelial cell development relationship: regulates GO:0060576 ! intestinal epithelial cell development created_by: rph creation_date: 2016-06-30T11:40:47Z [Term] id: GO:1905299 name: negative regulation of intestinal epithelial cell development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of intestinal epithelial cell development." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23904268] synonym: "down regulation of intestinal epithelial cell development" EXACT [GOC:TermGenie] synonym: "down-regulation of intestinal epithelial cell development" EXACT [GOC:TermGenie] synonym: "downregulation of intestinal epithelial cell development" EXACT [GOC:TermGenie] synonym: "inhibition of intestinal epithelial cell development" NARROW [GOC:TermGenie] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0030857 ! negative regulation of epithelial cell differentiation is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1905298 ! regulation of intestinal epithelial cell development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060576 ! intestinal epithelial cell development relationship: negatively_regulates GO:0060576 ! intestinal epithelial cell development created_by: rph creation_date: 2016-06-30T11:40:55Z [Term] id: GO:1905300 name: positive regulation of intestinal epithelial cell development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of intestinal epithelial cell development." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23904268] synonym: "activation of intestinal epithelial cell development" NARROW [GOC:TermGenie] synonym: "up regulation of intestinal epithelial cell development" EXACT [GOC:TermGenie] synonym: "up-regulation of intestinal epithelial cell development" EXACT [GOC:TermGenie] synonym: "upregulation of intestinal epithelial cell development" EXACT [GOC:TermGenie] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1905298 ! regulation of intestinal epithelial cell development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060576 ! intestinal epithelial cell development relationship: positively_regulates GO:0060576 ! intestinal epithelial cell development created_by: rph creation_date: 2016-06-30T11:41:02Z [Term] id: GO:1905304 name: regulation of cardiac myofibril assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac myofibril assembly." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:16151019] synonym: "regulation of cardiac myofibril development" EXACT [GOC:TermGenie] synonym: "regulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] synonym: "regulation of heart myofibril assembly" RELATED [GOC:TermGenie] is_a: GO:0060284 ! regulation of cell development is_a: GO:0110020 ! regulation of actomyosin structure organization is_a: GO:1902115 ! regulation of organelle assembly is_a: GO:1902903 ! regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0055003 ! cardiac myofibril assembly relationship: regulates GO:0055003 ! cardiac myofibril assembly created_by: rl creation_date: 2016-07-06T10:01:49Z [Term] id: GO:1905305 name: negative regulation of cardiac myofibril assembly namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac myofibril assembly." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:16151019] synonym: "down regulation of cardiac myofibril assembly" EXACT [GOC:TermGenie] synonym: "down regulation of cardiac myofibril development" EXACT [GOC:TermGenie] synonym: "down regulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] synonym: "down regulation of heart myofibril assembly" RELATED [GOC:TermGenie] synonym: "down-regulation of cardiac myofibril assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of cardiac myofibril development" EXACT [GOC:TermGenie] synonym: "down-regulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of heart myofibril assembly" RELATED [GOC:TermGenie] synonym: "downregulation of cardiac myofibril assembly" EXACT [GOC:TermGenie] synonym: "downregulation of cardiac myofibril development" EXACT [GOC:TermGenie] synonym: "downregulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of heart myofibril assembly" RELATED [GOC:TermGenie] synonym: "inhibition of cardiac myofibril assembly" NARROW [GOC:TermGenie] synonym: "inhibition of cardiac myofibril development" NARROW [GOC:TermGenie] synonym: "inhibition of cardiac myofibril morphogenesis" NARROW [GOC:TermGenie] synonym: "inhibition of heart myofibril assembly" RELATED [GOC:TermGenie] synonym: "negative regulation of cardiac myofibril development" EXACT [GOC:TermGenie] synonym: "negative regulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] synonym: "negative regulation of heart myofibril assembly" RELATED [GOC:TermGenie] is_a: GO:0051494 ! negative regulation of cytoskeleton organization is_a: GO:1902116 ! negative regulation of organelle assembly is_a: GO:1902904 ! negative regulation of supramolecular fiber organization is_a: GO:1905304 ! regulation of cardiac myofibril assembly is_a: GO:2000726 ! negative regulation of cardiac muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0055003 ! cardiac myofibril assembly relationship: negatively_regulates GO:0055003 ! cardiac myofibril assembly created_by: rl creation_date: 2016-07-06T10:01:58Z [Term] id: GO:1905306 name: positive regulation of cardiac myofibril assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cardiac myofibril assembly." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:16151019] synonym: "activation of cardiac myofibril assembly" NARROW [GOC:TermGenie] synonym: "activation of cardiac myofibril development" NARROW [GOC:TermGenie] synonym: "activation of cardiac myofibril morphogenesis" NARROW [GOC:TermGenie] synonym: "activation of heart myofibril assembly" RELATED [GOC:TermGenie] synonym: "positive regulation of cardiac myofibril development" EXACT [GOC:TermGenie] synonym: "positive regulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] synonym: "positive regulation of heart myofibril assembly" RELATED [GOC:TermGenie] synonym: "up regulation of cardiac myofibril assembly" EXACT [GOC:TermGenie] synonym: "up regulation of cardiac myofibril development" EXACT [GOC:TermGenie] synonym: "up regulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of heart myofibril assembly" RELATED [GOC:TermGenie] synonym: "up-regulation of cardiac myofibril assembly" EXACT [GOC:TermGenie] synonym: "up-regulation of cardiac myofibril development" EXACT [GOC:TermGenie] synonym: "up-regulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of heart myofibril assembly" RELATED [GOC:TermGenie] synonym: "upregulation of cardiac myofibril assembly" EXACT [GOC:TermGenie] synonym: "upregulation of cardiac myofibril development" EXACT [GOC:TermGenie] synonym: "upregulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of heart myofibril assembly" RELATED [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051495 ! positive regulation of cytoskeleton organization is_a: GO:1902117 ! positive regulation of organelle assembly is_a: GO:1902905 ! positive regulation of supramolecular fiber organization is_a: GO:1905304 ! regulation of cardiac myofibril assembly intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0055003 ! cardiac myofibril assembly relationship: positively_regulates GO:0055003 ! cardiac myofibril assembly created_by: rl creation_date: 2016-07-06T10:02:07Z [Term] id: GO:1905310 name: regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:17628518] is_a: GO:0030334 ! regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003253 ! cardiac neural crest cell migration involved in outflow tract morphogenesis relationship: regulates GO:0003253 ! cardiac neural crest cell migration involved in outflow tract morphogenesis created_by: rl creation_date: 2016-07-11T17:34:26Z [Term] id: GO:1905311 name: negative regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:17628518] synonym: "down regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of cardiac neural crest cell migration involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "inhibition of cardiac neural crest cell migration involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] is_a: GO:0030336 ! negative regulation of cell migration is_a: GO:1905310 ! regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0003253 ! cardiac neural crest cell migration involved in outflow tract morphogenesis relationship: negatively_regulates GO:0003253 ! cardiac neural crest cell migration involved in outflow tract morphogenesis created_by: rl creation_date: 2016-07-11T17:34:35Z [Term] id: GO:1905312 name: positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:17628518] synonym: "activation of cardiac neural crest cell migration involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] synonym: "up regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of cardiac neural crest cell migration involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0030335 ! positive regulation of cell migration is_a: GO:1905310 ! regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0003253 ! cardiac neural crest cell migration involved in outflow tract morphogenesis relationship: positively_regulates GO:0003253 ! cardiac neural crest cell migration involved in outflow tract morphogenesis created_by: rl creation_date: 2016-07-11T17:34:43Z [Term] id: GO:1905315 name: cell proliferation involved in endocardial cushion morphogenesis namespace: biological_process def: "Any cell proliferation that is involved in endocardial cushion morphogenesis." [GO_REF:0000060, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:20652948] is_a: GO:0061323 ! cell proliferation involved in heart morphogenesis intersection_of: GO:0008283 ! cell population proliferation intersection_of: part_of GO:0003203 ! endocardial cushion morphogenesis relationship: part_of GO:0003203 ! endocardial cushion morphogenesis created_by: rl creation_date: 2016-07-12T13:56:36Z [Term] id: GO:1905319 name: mesenchymal stem cell migration namespace: biological_process def: "The orderly movement of a mesenchymal stem cell from one site to another." [GO_REF:0000091, GOC:TermGenie, PMID:24924806, PMID:25181476] is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000134 ! mesenchymal stem cell relationship: results_in_movement_of CL:0000134 ! mesenchymal stem cell created_by: sl creation_date: 2016-07-14T17:13:02Z [Term] id: GO:1905320 name: regulation of mesenchymal stem cell migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mesenchymal stem cell migration." [GO_REF:0000058, GOC:TermGenie, PMID:26846297] is_a: GO:0030334 ! regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1905319 ! mesenchymal stem cell migration relationship: regulates GO:1905319 ! mesenchymal stem cell migration created_by: sl creation_date: 2016-07-15T22:19:14Z [Term] id: GO:1905321 name: negative regulation of mesenchymal stem cell migration namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell migration." [GO_REF:0000058, GOC:TermGenie, PMID:26846297] synonym: "down regulation of mesenchymal stem cell migration" EXACT [GOC:TermGenie] synonym: "down-regulation of mesenchymal stem cell migration" EXACT [GOC:TermGenie] synonym: "downregulation of mesenchymal stem cell migration" EXACT [GOC:TermGenie] synonym: "inhibition of mesenchymal stem cell migration" NARROW [GOC:TermGenie] is_a: GO:0030336 ! negative regulation of cell migration is_a: GO:1905320 ! regulation of mesenchymal stem cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1905319 ! mesenchymal stem cell migration relationship: negatively_regulates GO:1905319 ! mesenchymal stem cell migration created_by: sl creation_date: 2016-07-15T22:19:22Z [Term] id: GO:1905322 name: positive regulation of mesenchymal stem cell migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell migration." [GO_REF:0000058, GOC:TermGenie, PMID:26846297] synonym: "activation of mesenchymal stem cell migration" NARROW [GOC:TermGenie] synonym: "up regulation of mesenchymal stem cell migration" EXACT [GOC:TermGenie] synonym: "up-regulation of mesenchymal stem cell migration" EXACT [GOC:TermGenie] synonym: "upregulation of mesenchymal stem cell migration" EXACT [GOC:TermGenie] is_a: GO:0030335 ! positive regulation of cell migration is_a: GO:1905320 ! regulation of mesenchymal stem cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1905319 ! mesenchymal stem cell migration relationship: positively_regulates GO:1905319 ! mesenchymal stem cell migration created_by: sl creation_date: 2016-07-15T22:19:29Z [Term] id: GO:1905330 name: regulation of morphogenesis of an epithelium namespace: biological_process def: "Any process that modulates the frequency, rate or extent of morphogenesis of an epithelium." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:25745997] comment: An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay). synonym: "regulation of epithelium morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002009 ! morphogenesis of an epithelium relationship: regulates GO:0002009 ! morphogenesis of an epithelium created_by: bhm creation_date: 2016-07-22T07:13:49Z [Term] id: GO:1905331 name: negative regulation of morphogenesis of an epithelium namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of morphogenesis of an epithelium." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:25745997] comment: An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay). synonym: "down regulation of epithelium morphogenesis" EXACT [GOC:TermGenie] synonym: "down regulation of morphogenesis of an epithelium" EXACT [GOC:TermGenie] synonym: "down-regulation of epithelium morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of morphogenesis of an epithelium" EXACT [GOC:TermGenie] synonym: "downregulation of epithelium morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of morphogenesis of an epithelium" EXACT [GOC:TermGenie] synonym: "inhibition of epithelium morphogenesis" NARROW [GOC:TermGenie] synonym: "inhibition of morphogenesis of an epithelium" NARROW [GOC:TermGenie] synonym: "negative regulation of epithelium morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:1905330 ! regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002009 ! morphogenesis of an epithelium relationship: negatively_regulates GO:0002009 ! morphogenesis of an epithelium created_by: bhm creation_date: 2016-07-22T07:13:57Z [Term] id: GO:1905332 name: positive regulation of morphogenesis of an epithelium namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of morphogenesis of an epithelium." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:25745997] comment: An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay). synonym: "activation of epithelium morphogenesis" NARROW [GOC:TermGenie] synonym: "activation of morphogenesis of an epithelium" NARROW [GOC:TermGenie] synonym: "positive regulation of epithelium morphogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of epithelium morphogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of morphogenesis of an epithelium" EXACT [GOC:TermGenie] synonym: "up-regulation of epithelium morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of morphogenesis of an epithelium" EXACT [GOC:TermGenie] synonym: "upregulation of epithelium morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of morphogenesis of an epithelium" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:1905330 ! regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002009 ! morphogenesis of an epithelium relationship: positively_regulates GO:0002009 ! morphogenesis of an epithelium created_by: bhm creation_date: 2016-07-22T07:14:05Z [Term] id: GO:1905349 name: ciliary transition zone assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form a ciliary transition zone." [GO_REF:0000079, GOC:cilia, GOC:TermGenie, PMID:21725307, PMID:23644468, PMID:24448408, PMID:26595381, PMID:26982032] synonym: "cilial transition zone assembly" EXACT [GOC:TermGenie] synonym: "cilial transition zone formation" EXACT [GOC:TermGenie] synonym: "ciliary transition zone formation" EXACT [GOC:TermGenie] synonym: "cilium transition zone assembly" EXACT [GOC:TermGenie] synonym: "cilium transition zone formation" EXACT [GOC:TermGenie] is_a: GO:0022607 ! cellular component assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0035869 ! ciliary transition zone relationship: part_of GO:0060271 ! cilium assembly relationship: results_in_assembly_of GO:0035869 ! ciliary transition zone created_by: pr creation_date: 2016-08-04T14:49:43Z [Term] id: GO:1905383 name: protein localization to presynapse namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within a presynapse." [GO_REF:0000087, GOC:TermGenie, PMID:24449494] synonym: "protein localisation in presynapse" EXACT [GOC:TermGenie] synonym: "protein localisation to presynapse" EXACT [GOC:TermGenie] synonym: "protein localization in presynapse" EXACT [GOC:TermGenie] synonym: "recruitment of presynaptic proteins" EXACT [PMID:24449494] is_a: GO:0035418 ! protein localization to synapse intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0098793 ! presynapse relationship: has_target_end_location GO:0098793 ! presynapse created_by: dos creation_date: 2016-08-18T14:42:59Z [Term] id: GO:1905384 name: regulation of protein localization to presynapse namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein localization to presynapse." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24449494] synonym: "regulation of protein localisation in presynapse" EXACT [GOC:TermGenie] synonym: "regulation of protein localisation to presynapse" EXACT [GOC:TermGenie] synonym: "regulation of protein localization in presynapse" EXACT [GOC:TermGenie] synonym: "regulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] is_a: GO:1902473 ! regulation of protein localization to synapse intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1905383 ! protein localization to presynapse relationship: regulates GO:1905383 ! protein localization to presynapse created_by: dos creation_date: 2016-08-18T14:56:00Z [Term] id: GO:1905385 name: negative regulation of protein localization to presynapse namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to presynapse." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24449494] synonym: "down regulation of protein localisation in presynapse" EXACT [GOC:TermGenie] synonym: "down regulation of protein localisation to presynapse" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization in presynapse" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization to presynapse" EXACT [GOC:TermGenie] synonym: "down regulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation in presynapse" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation to presynapse" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization in presynapse" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to presynapse" EXACT [GOC:TermGenie] synonym: "down-regulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation in presynapse" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation to presynapse" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization in presynapse" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to presynapse" EXACT [GOC:TermGenie] synonym: "downregulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] synonym: "inhibition of protein localisation in presynapse" NARROW [GOC:TermGenie] synonym: "inhibition of protein localisation to presynapse" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization in presynapse" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization to presynapse" NARROW [GOC:TermGenie] synonym: "inhibition of recruitment of presynaptic proteins" NARROW [GOC:TermGenie] synonym: "negative regulation of protein localisation in presynapse" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localisation to presynapse" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localization in presynapse" EXACT [GOC:TermGenie] synonym: "negative regulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] is_a: GO:1903828 ! negative regulation of protein localization is_a: GO:1905384 ! regulation of protein localization to presynapse intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1905383 ! protein localization to presynapse relationship: negatively_regulates GO:1905383 ! protein localization to presynapse created_by: dos creation_date: 2016-08-18T14:56:08Z [Term] id: GO:1905386 name: positive regulation of protein localization to presynapse namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein localization to presynapse." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24449494] synonym: "activation of protein localisation in presynapse" NARROW [GOC:TermGenie] synonym: "activation of protein localisation to presynapse" NARROW [GOC:TermGenie] synonym: "activation of protein localization in presynapse" NARROW [GOC:TermGenie] synonym: "activation of protein localization to presynapse" NARROW [GOC:TermGenie] synonym: "activation of recruitment of presynaptic proteins" NARROW [GOC:TermGenie] synonym: "positive regulation of protein localisation in presynapse" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localisation to presynapse" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localization in presynapse" EXACT [GOC:TermGenie] synonym: "positive regulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation in presynapse" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation to presynapse" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization in presynapse" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization to presynapse" EXACT [GOC:TermGenie] synonym: "up regulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation in presynapse" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation to presynapse" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization in presynapse" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to presynapse" EXACT [GOC:TermGenie] synonym: "up-regulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation in presynapse" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation to presynapse" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization in presynapse" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to presynapse" EXACT [GOC:TermGenie] synonym: "upregulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] is_a: GO:1902474 ! positive regulation of protein localization to synapse is_a: GO:1905384 ! regulation of protein localization to presynapse intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1905383 ! protein localization to presynapse relationship: positively_regulates GO:1905383 ! protein localization to presynapse created_by: dos creation_date: 2016-08-18T14:56:21Z [Term] id: GO:1905432 name: regulation of retrograde trans-synaptic signaling by neuropeptide namespace: biological_process def: "Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:19448629] synonym: "regulation of neuropeptide-mediated retrograde trans-synaptic signaling" RELATED [GOC:bf] is_a: GO:0099177 ! regulation of trans-synaptic signaling intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0099082 ! retrograde trans-synaptic signaling by neuropeptide relationship: regulates GO:0099082 ! retrograde trans-synaptic signaling by neuropeptide created_by: bf creation_date: 2016-09-14T10:56:47Z [Term] id: GO:1905433 name: negative regulation of retrograde trans-synaptic signaling by neuropeptide namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:19448629] synonym: "down regulation of retrograde trans-synaptic signaling by neuropeptide" EXACT [GOC:TermGenie] synonym: "down-regulation of retrograde trans-synaptic signaling by neuropeptide" EXACT [GOC:TermGenie] synonym: "downregulation of retrograde trans-synaptic signaling by neuropeptide" EXACT [GOC:TermGenie] synonym: "inhibition of neuropeptide-mediated retrograde trans-synaptic signaling" RELATED [GOC:bf] synonym: "inhibition of retrograde trans-synaptic signaling by neuropeptide" NARROW [GOC:TermGenie] synonym: "negative regulation of neuropeptide-mediated retrograde trans-synaptic signaling" RELATED [GOC:bf] is_a: GO:0010648 ! negative regulation of cell communication is_a: GO:0023057 ! negative regulation of signaling is_a: GO:1905432 ! regulation of retrograde trans-synaptic signaling by neuropeptide intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0099082 ! retrograde trans-synaptic signaling by neuropeptide relationship: negatively_regulates GO:0099082 ! retrograde trans-synaptic signaling by neuropeptide created_by: bf creation_date: 2016-09-14T10:56:55Z [Term] id: GO:1905434 name: positive regulation of retrograde trans-synaptic signaling by neuropeptide namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:19448629] synonym: "activation of retrograde trans-synaptic signaling by neuropeptide" NARROW [GOC:TermGenie] synonym: "positive regulation of neuropeptide-mediated retrograde trans-synaptic signaling" RELATED [GOC:bf] synonym: "up regulation of retrograde trans-synaptic signaling by neuropeptide" EXACT [GOC:TermGenie] synonym: "up-regulation of retrograde trans-synaptic signaling by neuropeptide" EXACT [GOC:TermGenie] synonym: "upregulation of retrograde trans-synaptic signaling by neuropeptide" EXACT [GOC:TermGenie] is_a: GO:0010647 ! positive regulation of cell communication is_a: GO:0023056 ! positive regulation of signaling is_a: GO:1905432 ! regulation of retrograde trans-synaptic signaling by neuropeptide intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0099082 ! retrograde trans-synaptic signaling by neuropeptide relationship: positively_regulates GO:0099082 ! retrograde trans-synaptic signaling by neuropeptide created_by: bf creation_date: 2016-09-14T10:57:02Z [Term] id: GO:1905453 name: regulation of myeloid progenitor cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of myeloid progenitor cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:27010503] is_a: GO:1901532 ! regulation of hematopoietic progenitor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002318 ! myeloid progenitor cell differentiation relationship: regulates GO:0002318 ! myeloid progenitor cell differentiation created_by: rz creation_date: 2016-09-16T12:32:18Z [Term] id: GO:1905454 name: negative regulation of myeloid progenitor cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of myeloid progenitor cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:27010503] synonym: "down regulation of myeloid progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of myeloid progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of myeloid progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of myeloid progenitor cell differentiation" NARROW [GOC:TermGenie] is_a: GO:1901533 ! negative regulation of hematopoietic progenitor cell differentiation is_a: GO:1905453 ! regulation of myeloid progenitor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002318 ! myeloid progenitor cell differentiation relationship: negatively_regulates GO:0002318 ! myeloid progenitor cell differentiation created_by: rz creation_date: 2016-09-16T12:32:26Z [Term] id: GO:1905455 name: positive regulation of myeloid progenitor cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of myeloid progenitor cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:27010503] synonym: "activation of myeloid progenitor cell differentiation" NARROW [GOC:TermGenie] synonym: "up regulation of myeloid progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of myeloid progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of myeloid progenitor cell differentiation" EXACT [GOC:TermGenie] is_a: GO:1901534 ! positive regulation of hematopoietic progenitor cell differentiation is_a: GO:1905453 ! regulation of myeloid progenitor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002318 ! myeloid progenitor cell differentiation relationship: positively_regulates GO:0002318 ! myeloid progenitor cell differentiation created_by: rz creation_date: 2016-09-16T12:32:33Z [Term] id: GO:1905456 name: regulation of lymphoid progenitor cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of lymphoid progenitor cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:27010503] is_a: GO:1901532 ! regulation of hematopoietic progenitor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002320 ! lymphoid progenitor cell differentiation relationship: regulates GO:0002320 ! lymphoid progenitor cell differentiation created_by: rz creation_date: 2016-09-16T12:32:40Z [Term] id: GO:1905457 name: negative regulation of lymphoid progenitor cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of lymphoid progenitor cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:27010503] synonym: "down regulation of lymphoid progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of lymphoid progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of lymphoid progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of lymphoid progenitor cell differentiation" NARROW [GOC:TermGenie] is_a: GO:1901533 ! negative regulation of hematopoietic progenitor cell differentiation is_a: GO:1905456 ! regulation of lymphoid progenitor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002320 ! lymphoid progenitor cell differentiation relationship: negatively_regulates GO:0002320 ! lymphoid progenitor cell differentiation created_by: rz creation_date: 2016-09-16T12:32:48Z [Term] id: GO:1905458 name: positive regulation of lymphoid progenitor cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of lymphoid progenitor cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:27010503] synonym: "activation of lymphoid progenitor cell differentiation" NARROW [GOC:TermGenie] synonym: "up regulation of lymphoid progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of lymphoid progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of lymphoid progenitor cell differentiation" EXACT [GOC:TermGenie] is_a: GO:1901534 ! positive regulation of hematopoietic progenitor cell differentiation is_a: GO:1905456 ! regulation of lymphoid progenitor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002320 ! lymphoid progenitor cell differentiation relationship: positively_regulates GO:0002320 ! lymphoid progenitor cell differentiation created_by: rz creation_date: 2016-09-16T12:32:55Z [Term] id: GO:1905459 name: regulation of vascular associated smooth muscle cell apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:26493107] synonym: "regulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "regulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "regulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "regulation of VSMC apoptosis" NARROW [GOC:TermGenie] synonym: "regulation of VSMC apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0034391 ! regulation of smooth muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1905288 ! vascular associated smooth muscle cell apoptotic process relationship: regulates GO:1905288 ! vascular associated smooth muscle cell apoptotic process created_by: rph creation_date: 2016-09-19T11:33:54Z [Term] id: GO:1905460 name: negative regulation of vascular associated smooth muscle cell apoptotic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:26493107] synonym: "down regulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of vascular associated smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down regulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down regulation of VSMC apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of VSMC apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of vascular associated smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of VSMC apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of VSMC apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of vascular associated smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of VSMC apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of VSMC apoptotic process" EXACT [GOC:TermGenie] synonym: "inhibition of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of vascular associated smooth muscle cell apoptotic process" NARROW [GOC:TermGenie] synonym: "inhibition of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of vascular smooth muscle cell apoptotic process" NARROW [GOC:TermGenie] synonym: "inhibition of VSMC apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of VSMC apoptotic process" NARROW [GOC:TermGenie] synonym: "negative regulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "negative regulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "negative regulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "negative regulation of VSMC apoptosis" NARROW [GOC:TermGenie] synonym: "negative regulation of VSMC apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0034392 ! negative regulation of smooth muscle cell apoptotic process is_a: GO:1905459 ! regulation of vascular associated smooth muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1905288 ! vascular associated smooth muscle cell apoptotic process relationship: negatively_regulates GO:1905288 ! vascular associated smooth muscle cell apoptotic process created_by: rph creation_date: 2016-09-19T11:34:03Z [Term] id: GO:1905461 name: positive regulation of vascular associated smooth muscle cell apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:26493107] synonym: "activation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "activation of vascular associated smooth muscle cell apoptotic process" NARROW [GOC:TermGenie] synonym: "activation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "activation of vascular smooth muscle cell apoptotic process" NARROW [GOC:TermGenie] synonym: "activation of VSMC apoptosis" NARROW [GOC:TermGenie] synonym: "activation of VSMC apoptotic process" NARROW [GOC:TermGenie] synonym: "positive regulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "positive regulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "positive regulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "positive regulation of VSMC apoptosis" NARROW [GOC:TermGenie] synonym: "positive regulation of VSMC apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of vascular associated smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of VSMC apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of VSMC apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of vascular associated smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of VSMC apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of VSMC apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of vascular associated smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of VSMC apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of VSMC apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0034393 ! positive regulation of smooth muscle cell apoptotic process is_a: GO:1905459 ! regulation of vascular associated smooth muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1905288 ! vascular associated smooth muscle cell apoptotic process relationship: positively_regulates GO:1905288 ! vascular associated smooth muscle cell apoptotic process created_by: rph creation_date: 2016-09-19T11:34:10Z [Term] id: GO:1905475 name: regulation of protein localization to membrane namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein localization to membrane." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:26911690] synonym: "regulation of protein localisation in membrane" EXACT [GOC:TermGenie] synonym: "regulation of protein localization in membrane" EXACT [GOC:TermGenie] is_a: GO:0032880 ! regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0072657 ! protein localization to membrane relationship: regulates GO:0072657 ! protein localization to membrane created_by: bc creation_date: 2016-09-21T16:20:03Z [Term] id: GO:1905476 name: negative regulation of protein localization to membrane namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to membrane." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:26911690] synonym: "down regulation of protein localisation in membrane" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization in membrane" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization to membrane" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation in membrane" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization in membrane" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to membrane" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation in membrane" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization in membrane" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to membrane" EXACT [GOC:TermGenie] synonym: "inhibition of protein localisation in membrane" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization in membrane" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization to membrane" NARROW [GOC:TermGenie] synonym: "negative regulation of protein localisation in membrane" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localization in membrane" EXACT [GOC:TermGenie] is_a: GO:1903828 ! negative regulation of protein localization is_a: GO:1905475 ! regulation of protein localization to membrane intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0072657 ! protein localization to membrane relationship: negatively_regulates GO:0072657 ! protein localization to membrane created_by: bc creation_date: 2016-09-21T16:20:10Z [Term] id: GO:1905477 name: positive regulation of protein localization to membrane namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein localization to membrane." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:26911690] synonym: "activation of protein localisation in membrane" NARROW [GOC:TermGenie] synonym: "activation of protein localization in membrane" NARROW [GOC:TermGenie] synonym: "activation of protein localization to membrane" NARROW [GOC:TermGenie] synonym: "positive regulation of protein localisation in membrane" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localization in membrane" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation in membrane" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization in membrane" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization to membrane" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation in membrane" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization in membrane" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to membrane" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation in membrane" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization in membrane" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to membrane" EXACT [GOC:TermGenie] is_a: GO:1903829 ! positive regulation of protein localization is_a: GO:1905475 ! regulation of protein localization to membrane intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0072657 ! protein localization to membrane relationship: positively_regulates GO:0072657 ! protein localization to membrane created_by: bc creation_date: 2016-09-21T16:20:18Z [Term] id: GO:1905483 name: regulation of motor neuron migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of motor neuron migration." [GO_REF:0000058, GOC:TermGenie, PMID:16516839] is_a: GO:2001222 ! regulation of neuron migration intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0097475 ! motor neuron migration relationship: regulates GO:0097475 ! motor neuron migration created_by: hbye creation_date: 2016-09-23T12:49:54Z [Term] id: GO:1905484 name: negative regulation of motor neuron migration namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron migration." [GO_REF:0000058, GOC:TermGenie, PMID:16516839] synonym: "down regulation of motor neuron migration" EXACT [GOC:TermGenie] synonym: "down-regulation of motor neuron migration" EXACT [GOC:TermGenie] synonym: "downregulation of motor neuron migration" EXACT [GOC:TermGenie] synonym: "inhibition of motor neuron migration" NARROW [GOC:TermGenie] is_a: GO:1905483 ! regulation of motor neuron migration is_a: GO:2001223 ! negative regulation of neuron migration intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0097475 ! motor neuron migration relationship: negatively_regulates GO:0097475 ! motor neuron migration created_by: hbye creation_date: 2016-09-23T12:50:11Z [Term] id: GO:1905485 name: positive regulation of motor neuron migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of motor neuron migration." [GO_REF:0000058, GOC:TermGenie, PMID:16516839] synonym: "activation of motor neuron migration" NARROW [GOC:TermGenie] synonym: "up regulation of motor neuron migration" EXACT [GOC:TermGenie] synonym: "up-regulation of motor neuron migration" EXACT [GOC:TermGenie] synonym: "upregulation of motor neuron migration" EXACT [GOC:TermGenie] is_a: GO:1905483 ! regulation of motor neuron migration is_a: GO:2001224 ! positive regulation of neuron migration intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0097475 ! motor neuron migration relationship: positively_regulates GO:0097475 ! motor neuron migration created_by: hbye creation_date: 2016-09-23T12:50:19Z [Term] id: GO:1905492 name: positive regulation of branching morphogenesis of a nerve namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of branching morphogenesis of a nerve." [GO_REF:0000058, GOC:TermGenie, PMID:16516839] synonym: "activation of branching morphogenesis of a nerve" NARROW [GOC:TermGenie] synonym: "up regulation of branching morphogenesis of a nerve" EXACT [GOC:TermGenie] synonym: "up-regulation of branching morphogenesis of a nerve" EXACT [GOC:TermGenie] synonym: "upregulation of branching morphogenesis of a nerve" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:2000172 ! regulation of branching morphogenesis of a nerve intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048755 ! branching morphogenesis of a nerve relationship: positively_regulates GO:0048755 ! branching morphogenesis of a nerve created_by: hbye creation_date: 2016-09-23T14:11:52Z [Term] id: GO:1905503 name: regulation of motile cilium assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of motile cilium assembly." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:25294941] synonym: "regulation of motile primary cilia assembly" RELATED [GOC:TermGenie] synonym: "regulation of motile primary cilia formation" RELATED [GOC:TermGenie] synonym: "regulation of motile primary cilium assembly" RELATED [] synonym: "regulation of motile primary cilium formation" RELATED [GOC:TermGenie] synonym: "regulation of nodal cilium assembly" RELATED [GOC:TermGenie] synonym: "regulation of nodal cilium formation" RELATED [GOC:TermGenie] is_a: GO:1902017 ! regulation of cilium assembly intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0044458 ! motile cilium assembly relationship: regulates GO:0044458 ! motile cilium assembly created_by: krc creation_date: 2016-09-27T18:27:47Z [Term] id: GO:1905504 name: negative regulation of motile cilium assembly namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of motile cilium assembly." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:25294941] synonym: "down regulation of motile primary cilia assembly" RELATED [GOC:TermGenie] synonym: "down regulation of motile primary cilia formation" RELATED [GOC:TermGenie] synonym: "down regulation of motile primary cilium assembly" RELATED [GOC:TermGenie] synonym: "down regulation of motile primary cilium formation" RELATED [GOC:TermGenie] synonym: "down regulation of nodal cilium assembly" RELATED [GOC:TermGenie] synonym: "down regulation of nodal cilium formation" RELATED [GOC:TermGenie] synonym: "down-regulation of motile primary cilia assembly" RELATED [GOC:TermGenie] synonym: "down-regulation of motile primary cilia formation" RELATED [GOC:TermGenie] synonym: "down-regulation of motile primary cilium assembly" RELATED [GOC:TermGenie] synonym: "down-regulation of motile primary cilium formation" RELATED [GOC:TermGenie] synonym: "down-regulation of nodal cilium assembly" RELATED [GOC:TermGenie] synonym: "down-regulation of nodal cilium formation" RELATED [GOC:TermGenie] synonym: "downregulation of motile primary cilia assembly" RELATED [GOC:TermGenie] synonym: "downregulation of motile primary cilia formation" RELATED [GOC:TermGenie] synonym: "downregulation of motile primary cilium assembly" RELATED [GOC:TermGenie] synonym: "downregulation of motile primary cilium formation" RELATED [GOC:TermGenie] synonym: "downregulation of nodal cilium assembly" RELATED [GOC:TermGenie] synonym: "downregulation of nodal cilium formation" RELATED [GOC:TermGenie] synonym: "inhibition of motile primary cilia assembly" NARROW [GOC:TermGenie] synonym: "inhibition of motile primary cilia formation" NARROW [GOC:TermGenie] synonym: "inhibition of motile primary cilium assembly" NARROW [GOC:TermGenie] synonym: "inhibition of motile primary cilium formation" NARROW [GOC:TermGenie] synonym: "inhibition of nodal cilium assembly" RELATED [GOC:TermGenie] synonym: "inhibition of nodal cilium formation" RELATED [GOC:TermGenie] synonym: "negative regulation of motile primary cilia assembly" RELATED [GOC:TermGenie] synonym: "negative regulation of motile primary cilia formation" RELATED [GOC:TermGenie] synonym: "negative regulation of motile primary cilium assembly" RELATED [] synonym: "negative regulation of motile primary cilium formation" RELATED [GOC:TermGenie] synonym: "negative regulation of nodal cilium assembly" RELATED [GOC:TermGenie] synonym: "negative regulation of nodal cilium formation" RELATED [GOC:TermGenie] is_a: GO:1902018 ! negative regulation of cilium assembly is_a: GO:1905503 ! regulation of motile cilium assembly intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0044458 ! motile cilium assembly relationship: negatively_regulates GO:0044458 ! motile cilium assembly created_by: krc creation_date: 2016-09-27T18:27:55Z [Term] id: GO:1905505 name: positive regulation of motile cilium assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of motile cilium assembly." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:25294941] synonym: "activation of motile primary cilia assembly" NARROW [GOC:TermGenie] synonym: "activation of motile primary cilia formation" NARROW [GOC:TermGenie] synonym: "activation of motile primary cilium assembly" NARROW [GOC:TermGenie] synonym: "activation of motile primary cilium formation" NARROW [GOC:TermGenie] synonym: "activation of nodal cilium assembly" RELATED [GOC:TermGenie] synonym: "activation of nodal cilium formation" RELATED [GOC:TermGenie] synonym: "positive regulation of motile primary cilia assembly" RELATED [GOC:TermGenie] synonym: "positive regulation of motile primary cilia formation" RELATED [GOC:TermGenie] synonym: "positive regulation of motile primary cilium assembly" RELATED [] synonym: "positive regulation of motile primary cilium formation" RELATED [GOC:TermGenie] synonym: "positive regulation of nodal cilium assembly" RELATED [GOC:TermGenie] synonym: "positive regulation of nodal cilium formation" RELATED [GOC:TermGenie] synonym: "up regulation of motile primary cilia assembly" RELATED [GOC:TermGenie] synonym: "up regulation of motile primary cilia formation" RELATED [GOC:TermGenie] synonym: "up regulation of motile primary cilium assembly" RELATED [GOC:TermGenie] synonym: "up regulation of motile primary cilium formation" RELATED [GOC:TermGenie] synonym: "up regulation of nodal cilium assembly" RELATED [GOC:TermGenie] synonym: "up regulation of nodal cilium formation" RELATED [GOC:TermGenie] synonym: "up-regulation of motile primary cilia assembly" RELATED [GOC:TermGenie] synonym: "up-regulation of motile primary cilia formation" RELATED [GOC:TermGenie] synonym: "up-regulation of motile primary cilium assembly" RELATED [GOC:TermGenie] synonym: "up-regulation of motile primary cilium formation" RELATED [GOC:TermGenie] synonym: "up-regulation of nodal cilium assembly" RELATED [GOC:TermGenie] synonym: "up-regulation of nodal cilium formation" RELATED [GOC:TermGenie] synonym: "upregulation of motile primary cilia assembly" RELATED [GOC:TermGenie] synonym: "upregulation of motile primary cilia formation" RELATED [GOC:TermGenie] synonym: "upregulation of motile primary cilium assembly" RELATED [GOC:TermGenie] synonym: "upregulation of motile primary cilium formation" RELATED [GOC:TermGenie] synonym: "upregulation of nodal cilium assembly" RELATED [GOC:TermGenie] synonym: "upregulation of nodal cilium formation" RELATED [GOC:TermGenie] is_a: GO:0045724 ! positive regulation of cilium assembly is_a: GO:1905503 ! regulation of motile cilium assembly intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0044458 ! motile cilium assembly relationship: positively_regulates GO:0044458 ! motile cilium assembly created_by: krc creation_date: 2016-09-27T18:28:03Z [Term] id: GO:1905516 name: positive regulation of fertilization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of fertilization." [GO_REF:0000058, GOC:hbye, GOC:TermGenie, PMID:27564576] synonym: "activation of fertilization" NARROW [GOC:TermGenie] synonym: "activation of syngamy" NARROW [GOC:TermGenie] synonym: "positive regulation of syngamy" EXACT [GOC:TermGenie] synonym: "up regulation of fertilization" EXACT [GOC:TermGenie] synonym: "up regulation of syngamy" EXACT [GOC:TermGenie] synonym: "up-regulation of fertilization" EXACT [GOC:TermGenie] synonym: "up-regulation of syngamy" EXACT [GOC:TermGenie] synonym: "upregulation of fertilization" EXACT [GOC:TermGenie] synonym: "upregulation of syngamy" EXACT [GOC:TermGenie] is_a: GO:0080154 ! regulation of fertilization is_a: GO:2000243 ! positive regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0009566 ! fertilization relationship: positively_regulates GO:0009566 ! fertilization created_by: pr creation_date: 2016-09-30T14:32:32Z [Term] id: GO:1905553 name: regulation of blood vessel branching namespace: biological_process def: "Any process that modulates the frequency, rate or extent of blood vessel branching." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23201774] synonym: "regulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0045765 ! regulation of angiogenesis is_a: GO:0060688 ! regulation of morphogenesis of a branching structure is_a: GO:1905330 ! regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001569 ! branching involved in blood vessel morphogenesis relationship: regulates GO:0001569 ! branching involved in blood vessel morphogenesis created_by: nc creation_date: 2016-10-12T14:19:33Z [Term] id: GO:1905554 name: negative regulation of vessel branching namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of blood vessel branching." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23201774] synonym: "down regulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] synonym: "down regulation of patterning of blood vessels" EXACT [GOC:TermGenie] synonym: "down-regulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of patterning of blood vessels" EXACT [GOC:TermGenie] synonym: "downregulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of patterning of blood vessels" EXACT [GOC:TermGenie] synonym: "inhibition of branching involved in blood vessel morphogenesis" NARROW [GOC:TermGenie] synonym: "inhibition of patterning of blood vessels" NARROW [GOC:TermGenie] synonym: "negative regulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0016525 ! negative regulation of angiogenesis is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium is_a: GO:1905553 ! regulation of blood vessel branching intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001569 ! branching involved in blood vessel morphogenesis relationship: negatively_regulates GO:0001569 ! branching involved in blood vessel morphogenesis created_by: nc creation_date: 2016-10-12T14:19:41Z [Term] id: GO:1905555 name: positive regulation of blood vessel branching namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of blood vessel branching." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23201774] synonym: "activation of branching involved in blood vessel morphogenesis" NARROW [GOC:TermGenie] synonym: "activation of patterning of blood vessels" NARROW [GOC:TermGenie] synonym: "positive regulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of patterning of blood vessels" EXACT [GOC:TermGenie] synonym: "up-regulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of patterning of blood vessels" EXACT [GOC:TermGenie] synonym: "upregulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of patterning of blood vessels" EXACT [GOC:TermGenie] is_a: GO:0045766 ! positive regulation of angiogenesis is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium is_a: GO:1905553 ! regulation of blood vessel branching intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001569 ! branching involved in blood vessel morphogenesis relationship: positively_regulates GO:0001569 ! branching involved in blood vessel morphogenesis created_by: nc creation_date: 2016-10-12T14:19:49Z [Term] id: GO:1905557 name: regulation of mitotic nuclear envelope disassembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mitotic nuclear envelope disassembly." [GO_REF:0000058, GOC:TermGenie, PMID:18765790] synonym: "regulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] synonym: "regulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] synonym: "regulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] is_a: GO:0010549 ! regulation of membrane disassembly is_a: GO:0010564 ! regulation of cell cycle process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007077 ! mitotic nuclear membrane disassembly relationship: regulates GO:0007077 ! mitotic nuclear membrane disassembly created_by: hbye creation_date: 2016-10-14T13:14:57Z [Term] id: GO:1905558 name: negative regulation of mitotic nuclear envelope disassembly namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic nuclear envelope disassembly." [GO_REF:0000058, GOC:TermGenie, PMID:18765790] synonym: "down regulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] synonym: "down regulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] synonym: "down regulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] synonym: "down regulation of mitotic nuclear envelope disassembly" EXACT [GOC:TermGenie] synonym: "down-regulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] synonym: "down-regulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] synonym: "down-regulation of mitotic nuclear envelope disassembly" EXACT [GOC:TermGenie] synonym: "downregulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] synonym: "downregulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] synonym: "downregulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] synonym: "downregulation of mitotic nuclear envelope disassembly" EXACT [GOC:TermGenie] synonym: "inhibition of mitotic nuclear envelope breakdown" NARROW [GOC:TermGenie] synonym: "inhibition of mitotic nuclear envelope catabolism" NARROW [GOC:TermGenie] synonym: "inhibition of mitotic nuclear envelope degradation" NARROW [GOC:TermGenie] synonym: "inhibition of mitotic nuclear envelope disassembly" NARROW [GOC:TermGenie] synonym: "negative regulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] synonym: "negative regulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] is_a: GO:0010948 ! negative regulation of cell cycle process is_a: GO:0051129 ! negative regulation of cellular component organization is_a: GO:1905557 ! regulation of mitotic nuclear envelope disassembly intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007077 ! mitotic nuclear membrane disassembly relationship: negatively_regulates GO:0007077 ! mitotic nuclear membrane disassembly created_by: hbye creation_date: 2016-10-14T13:15:08Z [Term] id: GO:1905559 name: positive regulation of mitotic nuclear envelope disassembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mitotic nuclear envelope disassembly." [GO_REF:0000058, GOC:TermGenie, PMID:18765790] synonym: "activation of mitotic nuclear envelope breakdown" NARROW [GOC:TermGenie] synonym: "activation of mitotic nuclear envelope catabolism" NARROW [GOC:TermGenie] synonym: "activation of mitotic nuclear envelope degradation" NARROW [GOC:TermGenie] synonym: "activation of mitotic nuclear envelope disassembly" NARROW [GOC:TermGenie] synonym: "positive regulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] synonym: "positive regulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] synonym: "up regulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] synonym: "up regulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] synonym: "up regulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] synonym: "up regulation of mitotic nuclear envelope disassembly" EXACT [GOC:TermGenie] synonym: "up-regulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] synonym: "up-regulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] synonym: "up-regulation of mitotic nuclear envelope disassembly" EXACT [GOC:TermGenie] synonym: "upregulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] synonym: "upregulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] synonym: "upregulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] synonym: "upregulation of mitotic nuclear envelope disassembly" EXACT [GOC:TermGenie] is_a: GO:0051130 ! positive regulation of cellular component organization is_a: GO:0090068 ! positive regulation of cell cycle process is_a: GO:1905557 ! regulation of mitotic nuclear envelope disassembly intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007077 ! mitotic nuclear membrane disassembly relationship: positively_regulates GO:0007077 ! mitotic nuclear membrane disassembly created_by: hbye creation_date: 2016-10-14T13:15:17Z [Term] id: GO:1905562 name: regulation of vascular endothelial cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of vascular endothelial cell proliferation." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23201774] is_a: GO:0001936 ! regulation of endothelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0101023 ! vascular endothelial cell proliferation relationship: regulates GO:0101023 ! vascular endothelial cell proliferation created_by: nc creation_date: 2016-10-17T09:24:17Z [Term] id: GO:1905563 name: negative regulation of vascular endothelial cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial cell proliferation." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23201774] synonym: "down regulation of vascular endothelial cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of vascular endothelial cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of vascular endothelial cell proliferation" EXACT [GOC:TermGenie] synonym: "inhibition of vascular endothelial cell proliferation" NARROW [GOC:TermGenie] is_a: GO:0001937 ! negative regulation of endothelial cell proliferation is_a: GO:1905562 ! regulation of vascular endothelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0101023 ! vascular endothelial cell proliferation relationship: negatively_regulates GO:0101023 ! vascular endothelial cell proliferation created_by: nc creation_date: 2016-10-17T09:24:26Z [Term] id: GO:1905564 name: positive regulation of vascular endothelial cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of vascular endothelial cell proliferation." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23201774] synonym: "activation of vascular endothelial cell proliferation" NARROW [GOC:TermGenie] synonym: "up regulation of vascular endothelial cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of vascular endothelial cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of vascular endothelial cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0001938 ! positive regulation of endothelial cell proliferation is_a: GO:1905562 ! regulation of vascular endothelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0101023 ! vascular endothelial cell proliferation relationship: positively_regulates GO:0101023 ! vascular endothelial cell proliferation created_by: nc creation_date: 2016-10-17T09:24:35Z [Term] id: GO:1905606 name: regulation of presynapse assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of presynapse assembly." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:25533483] subset: goslim_synapse synonym: "regulation of presynapse biogenesis" EXACT [GOC:TermGenie] synonym: "regulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] is_a: GO:0051963 ! regulation of synapse assembly is_a: GO:0099174 ! regulation of presynapse organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0099054 ! presynapse assembly relationship: regulates GO:0099054 ! presynapse assembly created_by: bc creation_date: 2016-10-27T16:08:13Z [Term] id: GO:1905607 name: negative regulation of presynapse assembly namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of presynapse assembly." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:25533483] synonym: "down regulation of presynapse assembly" EXACT [GOC:TermGenie] synonym: "down regulation of presynapse biogenesis" EXACT [GOC:TermGenie] synonym: "down regulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of presynapse assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of presynapse biogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] synonym: "downregulation of presynapse assembly" EXACT [GOC:TermGenie] synonym: "downregulation of presynapse biogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] synonym: "inhibition of presynapse assembly" NARROW [GOC:TermGenie] synonym: "inhibition of presynapse biogenesis" NARROW [GOC:TermGenie] synonym: "inhibition of presynaptic terminal assembly" NARROW [GOC:TermGenie] synonym: "negative regulation of presynapse biogenesis" EXACT [GOC:TermGenie] synonym: "negative regulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] is_a: GO:0051964 ! negative regulation of synapse assembly is_a: GO:1905606 ! regulation of presynapse assembly intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0099054 ! presynapse assembly relationship: negatively_regulates GO:0099054 ! presynapse assembly created_by: bc creation_date: 2016-10-27T16:08:20Z [Term] id: GO:1905608 name: positive regulation of presynapse assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of presynapse assembly." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:25533483] synonym: "activation of presynapse assembly" NARROW [GOC:TermGenie] synonym: "activation of presynapse biogenesis" NARROW [GOC:TermGenie] synonym: "activation of presynaptic terminal assembly" NARROW [GOC:TermGenie] synonym: "positive regulation of presynapse biogenesis" EXACT [GOC:TermGenie] synonym: "positive regulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] synonym: "up regulation of presynapse assembly" EXACT [GOC:TermGenie] synonym: "up regulation of presynapse biogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] synonym: "up-regulation of presynapse assembly" EXACT [GOC:TermGenie] synonym: "up-regulation of presynapse biogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] synonym: "upregulation of presynapse assembly" EXACT [GOC:TermGenie] synonym: "upregulation of presynapse biogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] is_a: GO:0051130 ! positive regulation of cellular component organization is_a: GO:1905606 ! regulation of presynapse assembly intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0099054 ! presynapse assembly relationship: positively_regulates GO:0099054 ! presynapse assembly created_by: bc creation_date: 2016-10-27T16:08:28Z [Term] id: GO:1905627 name: regulation of serotonin biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of serotonin biosynthetic process." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:25642596] synonym: "regulation of serotonin anabolism" EXACT [GOC:TermGenie] synonym: "regulation of serotonin biosynthesis" EXACT [GOC:TermGenie] synonym: "regulation of serotonin formation" EXACT [GOC:TermGenie] synonym: "regulation of serotonin synthesis" EXACT [GOC:TermGenie] is_a: GO:0009889 ! regulation of biosynthetic process is_a: GO:0031323 ! regulation of cellular metabolic process is_a: GO:0051171 ! regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0042427 ! serotonin biosynthetic process relationship: regulates GO:0042427 ! serotonin biosynthetic process created_by: pad creation_date: 2016-10-31T14:26:20Z [Term] id: GO:1905628 name: negative regulation of serotonin biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of serotonin biosynthetic process." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:25642596] synonym: "down regulation of serotonin anabolism" EXACT [GOC:TermGenie] synonym: "down regulation of serotonin biosynthesis" EXACT [GOC:TermGenie] synonym: "down regulation of serotonin biosynthetic process" EXACT [GOC:TermGenie] synonym: "down regulation of serotonin formation" EXACT [GOC:TermGenie] synonym: "down regulation of serotonin synthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of serotonin anabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of serotonin biosynthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of serotonin biosynthetic process" EXACT [GOC:TermGenie] synonym: "down-regulation of serotonin formation" EXACT [GOC:TermGenie] synonym: "down-regulation of serotonin synthesis" EXACT [GOC:TermGenie] synonym: "downregulation of serotonin anabolism" EXACT [GOC:TermGenie] synonym: "downregulation of serotonin biosynthesis" EXACT [GOC:TermGenie] synonym: "downregulation of serotonin biosynthetic process" EXACT [GOC:TermGenie] synonym: "downregulation of serotonin formation" EXACT [GOC:TermGenie] synonym: "downregulation of serotonin synthesis" EXACT [GOC:TermGenie] synonym: "inhibition of serotonin anabolism" NARROW [GOC:TermGenie] synonym: "inhibition of serotonin biosynthesis" NARROW [GOC:TermGenie] synonym: "inhibition of serotonin biosynthetic process" NARROW [GOC:TermGenie] synonym: "inhibition of serotonin formation" NARROW [GOC:TermGenie] synonym: "inhibition of serotonin synthesis" NARROW [GOC:TermGenie] synonym: "negative regulation of serotonin anabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of serotonin biosynthesis" EXACT [GOC:TermGenie] synonym: "negative regulation of serotonin formation" EXACT [GOC:TermGenie] synonym: "negative regulation of serotonin synthesis" EXACT [GOC:TermGenie] is_a: GO:0009890 ! negative regulation of biosynthetic process is_a: GO:0031324 ! negative regulation of cellular metabolic process is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process is_a: GO:1905627 ! regulation of serotonin biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0042427 ! serotonin biosynthetic process relationship: negatively_regulates GO:0042427 ! serotonin biosynthetic process created_by: pad creation_date: 2016-10-31T14:26:28Z [Term] id: GO:1905629 name: positive regulation of serotonin biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of serotonin biosynthetic process." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:25642596] synonym: "activation of serotonin anabolism" NARROW [GOC:TermGenie] synonym: "activation of serotonin biosynthesis" NARROW [GOC:TermGenie] synonym: "activation of serotonin biosynthetic process" NARROW [GOC:TermGenie] synonym: "activation of serotonin formation" NARROW [GOC:TermGenie] synonym: "activation of serotonin synthesis" NARROW [GOC:TermGenie] synonym: "positive regulation of serotonin anabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of serotonin biosynthesis" EXACT [GOC:TermGenie] synonym: "positive regulation of serotonin formation" EXACT [GOC:TermGenie] synonym: "positive regulation of serotonin synthesis" EXACT [GOC:TermGenie] synonym: "up regulation of serotonin anabolism" EXACT [GOC:TermGenie] synonym: "up regulation of serotonin biosynthesis" EXACT [GOC:TermGenie] synonym: "up regulation of serotonin biosynthetic process" EXACT [GOC:TermGenie] synonym: "up regulation of serotonin formation" EXACT [GOC:TermGenie] synonym: "up regulation of serotonin synthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of serotonin anabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of serotonin biosynthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of serotonin biosynthetic process" EXACT [GOC:TermGenie] synonym: "up-regulation of serotonin formation" EXACT [GOC:TermGenie] synonym: "up-regulation of serotonin synthesis" EXACT [GOC:TermGenie] synonym: "upregulation of serotonin anabolism" EXACT [GOC:TermGenie] synonym: "upregulation of serotonin biosynthesis" EXACT [GOC:TermGenie] synonym: "upregulation of serotonin biosynthetic process" EXACT [GOC:TermGenie] synonym: "upregulation of serotonin formation" EXACT [GOC:TermGenie] synonym: "upregulation of serotonin synthesis" EXACT [GOC:TermGenie] is_a: GO:0009891 ! positive regulation of biosynthetic process is_a: GO:0031325 ! positive regulation of cellular metabolic process is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process is_a: GO:1905627 ! regulation of serotonin biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0042427 ! serotonin biosynthetic process relationship: positively_regulates GO:0042427 ! serotonin biosynthetic process created_by: pad creation_date: 2016-10-31T14:26:36Z [Term] id: GO:1905634 name: regulation of protein localization to chromatin namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein localization to chromatin." [GO_REF:0000058, GOC:TermGenie, PMID:20889714] synonym: "regulation of protein localisation to chromatin" EXACT [GOC:TermGenie] is_a: GO:0032880 ! regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0071168 ! protein localization to chromatin relationship: regulates GO:0071168 ! protein localization to chromatin created_by: pga creation_date: 2016-11-01T16:33:52Z [Term] id: GO:1905651 name: regulation of artery morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of artery morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:27389411] synonym: "regulation of arterial morphogenesis" EXACT [GOC:TermGenie] synonym: "regulation of arteriogenesis" EXACT [GOC:TermGenie] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048844 ! artery morphogenesis relationship: regulates GO:0048844 ! artery morphogenesis created_by: rph creation_date: 2016-11-09T12:19:37Z [Term] id: GO:1905652 name: negative regulation of artery morphogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of artery morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:27389411] synonym: "down regulation of arterial morphogenesis" EXACT [GOC:TermGenie] synonym: "down regulation of arteriogenesis" EXACT [GOC:TermGenie] synonym: "down regulation of artery morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of arterial morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of arteriogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of artery morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of arterial morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of arteriogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of artery morphogenesis" EXACT [GOC:TermGenie] synonym: "inhibition of arterial morphogenesis" NARROW [GOC:TermGenie] synonym: "inhibition of arteriogenesis" NARROW [GOC:TermGenie] synonym: "inhibition of artery morphogenesis" NARROW [GOC:TermGenie] synonym: "negative regulation of arterial morphogenesis" EXACT [GOC:TermGenie] synonym: "negative regulation of arteriogenesis" EXACT [GOC:TermGenie] is_a: GO:1905651 ! regulation of artery morphogenesis is_a: GO:2000181 ! negative regulation of blood vessel morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048844 ! artery morphogenesis relationship: negatively_regulates GO:0048844 ! artery morphogenesis created_by: rph creation_date: 2016-11-09T12:19:53Z [Term] id: GO:1905653 name: positive regulation of artery morphogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of artery morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:27389411] synonym: "activation of arterial morphogenesis" NARROW [GOC:TermGenie] synonym: "activation of arteriogenesis" NARROW [GOC:TermGenie] synonym: "activation of artery morphogenesis" NARROW [GOC:TermGenie] synonym: "positive regulation of arterial morphogenesis" EXACT [GOC:TermGenie] synonym: "positive regulation of arteriogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of arterial morphogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of arteriogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of artery morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of arterial morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of arteriogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of artery morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of arterial morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of arteriogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of artery morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:1905651 ! regulation of artery morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048844 ! artery morphogenesis relationship: positively_regulates GO:0048844 ! artery morphogenesis created_by: rph creation_date: 2016-11-09T12:20:01Z [Term] id: GO:1905690 name: nucleus disassembly namespace: biological_process def: "The disaggregation of a nucleus into its constituent components." [GO_REF:0000079, GOC:autophagy, GOC:pr, GOC:TermGenie] synonym: "cell nucleus disassembly" EXACT [GOC:TermGenie] is_a: GO:0006997 ! nucleus organization is_a: GO:1903008 ! organelle disassembly intersection_of: GO:0022411 ! cellular component disassembly intersection_of: results_in_disassembly_of GO:0005634 ! nucleus relationship: results_in_disassembly_of GO:0005634 ! nucleus created_by: pr creation_date: 2016-11-14T13:38:57Z [Term] id: GO:1905720 name: cytoplasmic microtubule bundle namespace: cellular_component def: "Any microtubule bundle that is part of a cytoplasm." [GO_REF:0000064, GOC:TermGenie, PMID:11007487, PMID:26124291] synonym: "microtubule bundle of cytoplasm" EXACT [GOC:TermGenie] synonym: "microtubule fascicle of cytoplasm" EXACT [GOC:TermGenie] is_a: GO:0097427 ! microtubule bundle intersection_of: GO:0097427 ! microtubule bundle intersection_of: part_of GO:0005737 ! cytoplasm relationship: part_of GO:0005737 ! cytoplasm created_by: mah creation_date: 2016-11-24T16:52:02Z [Term] id: GO:1905755 name: protein localization to cytoplasmic microtubule namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within a cytoplasmic microtubule." [GO_REF:0000087, GOC:TermGenie, PMID:15177031] synonym: "protein localisation to cytoplasmic microtubule" EXACT [GOC:TermGenie] is_a: GO:0035372 ! protein localization to microtubule intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0005881 ! cytoplasmic microtubule relationship: has_target_end_location GO:0005881 ! cytoplasmic microtubule created_by: mah creation_date: 2016-12-12T15:31:07Z [Term] id: GO:1905770 name: regulation of mesodermal cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mesodermal cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23765923] synonym: "regulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048333 ! mesodermal cell differentiation relationship: regulates GO:0048333 ! mesodermal cell differentiation created_by: rph creation_date: 2016-12-21T12:44:13Z [Term] id: GO:1905771 name: negative regulation of mesodermal cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesodermal cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23765923] synonym: "down regulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of mesodermal cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of mesodermal cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of mesodermal cell differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of mesoderm cell differentiation" NARROW [GOC:TermGenie] synonym: "inhibition of mesodermal cell differentiation" NARROW [GOC:TermGenie] synonym: "negative regulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:1905770 ! regulation of mesodermal cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048333 ! mesodermal cell differentiation relationship: negatively_regulates GO:0048333 ! mesodermal cell differentiation created_by: rph creation_date: 2016-12-21T12:44:23Z [Term] id: GO:1905772 name: positive regulation of mesodermal cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mesodermal cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23765923] synonym: "activation of mesoderm cell differentiation" NARROW [GOC:TermGenie] synonym: "activation of mesodermal cell differentiation" NARROW [GOC:TermGenie] synonym: "positive regulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of mesodermal cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of mesodermal cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of mesodermal cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:1905770 ! regulation of mesodermal cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048333 ! mesodermal cell differentiation relationship: positively_regulates GO:0048333 ! mesodermal cell differentiation created_by: rph creation_date: 2016-12-21T12:44:32Z [Term] id: GO:1905806 name: regulation of synapse pruning namespace: biological_process def: "Any process that modulates the frequency, rate or extent of synapse pruning." [GO_REF:0000058, GOC:TermGenie, PMID:27779093] subset: goslim_synapse synonym: "regulation of synapse clearance" EXACT [] synonym: "regulation of synapse disassembly" EXACT syngo_official_label [] synonym: "regulation of synapse elimination" EXACT [] synonym: "regulation of synapse removal" EXACT [] is_a: GO:0050807 ! regulation of synapse organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0098883 ! synapse pruning relationship: regulates GO:0098883 ! synapse pruning created_by: tb creation_date: 2017-01-11T22:03:15Z [Term] id: GO:1905807 name: negative regulation of synapse pruning namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of synapse pruning." [GO_REF:0000058, GOC:TermGenie, PMID:27779093] synonym: "down regulation of synapse disassembly" EXACT [GOC:TermGenie] synonym: "down-regulation of synapse disassembly" EXACT [GOC:TermGenie] synonym: "downregulation of synapse disassembly" EXACT [GOC:TermGenie] synonym: "inhibition of synapse disassembly" NARROW [GOC:TermGenie] synonym: "regulation of synapse clearance" BROAD [] synonym: "regulation of synapse disassembly" BROAD [] synonym: "regulation of synapse elimination" BROAD [] synonym: "regulation of synapse removal" BROAD [] is_a: GO:1905806 ! regulation of synapse pruning is_a: GO:1905809 ! negative regulation of synapse organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0098883 ! synapse pruning relationship: negatively_regulates GO:0098883 ! synapse pruning created_by: tb creation_date: 2017-01-11T22:03:24Z [Term] id: GO:1905808 name: positive regulation of synapse pruning namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of synapse pruning." [GO_REF:0000058, GOC:TermGenie, PMID:27779093] synonym: "activation of synapse disassembly" NARROW [GOC:TermGenie] synonym: "regulation of synapse clearance" BROAD [] synonym: "regulation of synapse disassembly" BROAD [] synonym: "regulation of synapse elimination" BROAD [] synonym: "regulation of synapse removal" BROAD [] synonym: "up regulation of synapse disassembly" EXACT [GOC:TermGenie] synonym: "up-regulation of synapse disassembly" EXACT [GOC:TermGenie] synonym: "upregulation of synapse disassembly" EXACT [GOC:TermGenie] is_a: GO:0051130 ! positive regulation of cellular component organization is_a: GO:1905806 ! regulation of synapse pruning intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0098883 ! synapse pruning relationship: positively_regulates GO:0098883 ! synapse pruning created_by: tb creation_date: 2017-01-11T22:03:33Z [Term] id: GO:1905809 name: negative regulation of synapse organization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of synapse organization." [GO_REF:0000058, GOC:TermGenie, PMID:27779093] synonym: "down regulation of synapse development" EXACT [GOC:TermGenie] synonym: "down regulation of synapse morphogenesis" RELATED [GOC:TermGenie] synonym: "down regulation of synapse organisation" EXACT [GOC:TermGenie] synonym: "down regulation of synapse organization" EXACT [GOC:TermGenie] synonym: "down regulation of synapse organization and biogenesis" RELATED [GOC:TermGenie] synonym: "down-regulation of synapse development" EXACT [GOC:TermGenie] synonym: "down-regulation of synapse morphogenesis" RELATED [GOC:TermGenie] synonym: "down-regulation of synapse organisation" EXACT [GOC:TermGenie] synonym: "down-regulation of synapse organization" EXACT [GOC:TermGenie] synonym: "down-regulation of synapse organization and biogenesis" RELATED [GOC:TermGenie] synonym: "downregulation of synapse development" EXACT [GOC:TermGenie] synonym: "downregulation of synapse morphogenesis" RELATED [GOC:TermGenie] synonym: "downregulation of synapse organisation" EXACT [GOC:TermGenie] synonym: "downregulation of synapse organization" EXACT [GOC:TermGenie] synonym: "downregulation of synapse organization and biogenesis" RELATED [GOC:TermGenie] synonym: "inhibition of synapse development" NARROW [GOC:TermGenie] synonym: "inhibition of synapse morphogenesis" RELATED [GOC:TermGenie] synonym: "inhibition of synapse organisation" NARROW [GOC:TermGenie] synonym: "inhibition of synapse organization" NARROW [GOC:TermGenie] synonym: "inhibition of synapse organization and biogenesis" RELATED [GOC:TermGenie] synonym: "negative regulation of synapse development" EXACT [GOC:TermGenie] synonym: "negative regulation of synapse morphogenesis" RELATED [GOC:TermGenie] synonym: "negative regulation of synapse organisation" EXACT [GOC:TermGenie] synonym: "negative regulation of synapse organization and biogenesis" RELATED [GOC:TermGenie] is_a: GO:0050807 ! regulation of synapse organization is_a: GO:0051129 ! negative regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0050808 ! synapse organization relationship: negatively_regulates GO:0050808 ! synapse organization created_by: tb creation_date: 2017-01-11T22:03:41Z [Term] id: GO:1905821 name: positive regulation of chromosome condensation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of chromosome condensation." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:17268547] synonym: "activation of chromosome condensation" NARROW [GOC:TermGenie] synonym: "activation of eukaryotic chromosome condensation" NARROW [GOC:TermGenie] synonym: "activation of nuclear chromosome condensation" NARROW [GOC:TermGenie] synonym: "positive regulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie] synonym: "positive regulation of nuclear chromosome condensation" EXACT [GOC:TermGenie] synonym: "up regulation of chromosome condensation" EXACT [GOC:TermGenie] synonym: "up regulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie] synonym: "up regulation of nuclear chromosome condensation" EXACT [GOC:TermGenie] synonym: "up-regulation of chromosome condensation" EXACT [GOC:TermGenie] synonym: "up-regulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie] synonym: "up-regulation of nuclear chromosome condensation" EXACT [GOC:TermGenie] synonym: "upregulation of chromosome condensation" EXACT [GOC:TermGenie] synonym: "upregulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie] synonym: "upregulation of nuclear chromosome condensation" EXACT [GOC:TermGenie] is_a: GO:0060623 ! regulation of chromosome condensation is_a: GO:2001252 ! positive regulation of chromosome organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030261 ! chromosome condensation relationship: positively_regulates GO:0030261 ! chromosome condensation created_by: bhm creation_date: 2017-01-13T14:13:44Z [Term] id: GO:1905833 name: negative regulation of microtubule nucleation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of microtubule nucleation." [GO_REF:0000058, GOC:TermGenie, PMID:27689799] synonym: "down regulation of microtubule nucleation" EXACT [GOC:TermGenie] synonym: "down-regulation of microtubule nucleation" EXACT [GOC:TermGenie] synonym: "downregulation of microtubule nucleation" EXACT [GOC:TermGenie] synonym: "inhibition of microtubule nucleation" NARROW [GOC:TermGenie] is_a: GO:0010968 ! regulation of microtubule nucleation is_a: GO:0031115 ! negative regulation of microtubule polymerization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007020 ! microtubule nucleation relationship: negatively_regulates GO:0007020 ! microtubule nucleation created_by: hbye creation_date: 2017-01-17T12:00:56Z [Term] id: GO:1905867 name: epididymis development namespace: biological_process def: "The process whose specific outcome is the progression of an epididymis over time, from its formation to the mature structure." [GO_REF:0000094, GOC:TermGenie, PMID:12388089] synonym: "epididymus development" EXACT [GOC:TermGenie] is_a: GO:0035295 ! tube development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001301 ! epididymis relationship: results_in_development_of UBERON:0001301 ! epididymis created_by: sl creation_date: 2017-01-27T00:00:33Z [Term] id: GO:1905871 name: regulation of protein localization to cell leading edge namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein localization to cell leading edge." [GO_REF:0000058, GOC:TermGenie, PMID:26324884] synonym: "regulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] synonym: "regulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] synonym: "regulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] is_a: GO:0032880 ! regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1902463 ! protein localization to cell leading edge relationship: regulates GO:1902463 ! protein localization to cell leading edge created_by: sl creation_date: 2017-01-27T19:34:55Z [Term] id: GO:1905872 name: negative regulation of protein localization to cell leading edge namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell leading edge." [GO_REF:0000058, GOC:TermGenie, PMID:26324884] synonym: "down regulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] synonym: "down regulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization to cell leading edge" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to cell leading edge" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to cell leading edge" EXACT [GOC:TermGenie] synonym: "inhibition of protein localisation in cell leading edge" NARROW [GOC:TermGenie] synonym: "inhibition of protein localisation to cell leading edge" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization in cell leading edge" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization to cell leading edge" NARROW [GOC:TermGenie] synonym: "negative regulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] is_a: GO:1903828 ! negative regulation of protein localization is_a: GO:1905871 ! regulation of protein localization to cell leading edge intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1902463 ! protein localization to cell leading edge relationship: negatively_regulates GO:1902463 ! protein localization to cell leading edge created_by: sl creation_date: 2017-01-27T19:35:04Z [Term] id: GO:1905873 name: positive regulation of protein localization to cell leading edge namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein localization to cell leading edge." [GO_REF:0000058, GOC:TermGenie, PMID:26324884] synonym: "activation of protein localisation in cell leading edge" NARROW [GOC:TermGenie] synonym: "activation of protein localisation to cell leading edge" NARROW [GOC:TermGenie] synonym: "activation of protein localization in cell leading edge" NARROW [GOC:TermGenie] synonym: "activation of protein localization to cell leading edge" NARROW [GOC:TermGenie] synonym: "positive regulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization to cell leading edge" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to cell leading edge" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to cell leading edge" EXACT [GOC:TermGenie] is_a: GO:1903829 ! positive regulation of protein localization is_a: GO:1905871 ! regulation of protein localization to cell leading edge intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1902463 ! protein localization to cell leading edge relationship: positively_regulates GO:1902463 ! protein localization to cell leading edge created_by: sl creation_date: 2017-01-27T19:35:13Z [Term] id: GO:1905879 name: regulation of oogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of oogenesis." [GO_REF:0000058, GOC:TermGenie, PMID:26434723] synonym: "regulation of ovum development" EXACT [GOC:TermGenie] is_a: GO:0051239 ! regulation of multicellular organismal process is_a: GO:0060284 ! regulation of cell development is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048477 ! oogenesis relationship: regulates GO:0048477 ! oogenesis created_by: hbye creation_date: 2017-01-31T09:31:05Z [Term] id: GO:1905880 name: negative regulation of oogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of oogenesis." [GO_REF:0000058, GOC:TermGenie, PMID:26434723] synonym: "down regulation of oogenesis" EXACT [GOC:TermGenie] synonym: "down regulation of ovum development" EXACT [GOC:TermGenie] synonym: "down-regulation of oogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of ovum development" EXACT [GOC:TermGenie] synonym: "downregulation of oogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of ovum development" EXACT [GOC:TermGenie] synonym: "inhibition of oogenesis" NARROW [GOC:TermGenie] synonym: "inhibition of ovum development" NARROW [GOC:TermGenie] synonym: "negative regulation of ovum development" EXACT [GOC:TermGenie] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1905879 ! regulation of oogenesis is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048477 ! oogenesis relationship: negatively_regulates GO:0048477 ! oogenesis created_by: hbye creation_date: 2017-01-31T09:31:15Z [Term] id: GO:1905881 name: positive regulation of oogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of oogenesis." [GO_REF:0000058, GOC:TermGenie, PMID:26434723] synonym: "activation of oogenesis" NARROW [GOC:TermGenie] synonym: "activation of ovum development" NARROW [GOC:TermGenie] synonym: "positive regulation of ovum development" EXACT [GOC:TermGenie] synonym: "up regulation of oogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of ovum development" EXACT [GOC:TermGenie] synonym: "up-regulation of oogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of ovum development" EXACT [GOC:TermGenie] synonym: "upregulation of oogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of ovum development" EXACT [GOC:TermGenie] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1905879 ! regulation of oogenesis is_a: GO:2000243 ! positive regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048477 ! oogenesis relationship: positively_regulates GO:0048477 ! oogenesis created_by: hbye creation_date: 2017-01-31T09:31:23Z [Term] id: GO:1905899 name: regulation of smooth muscle tissue development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of smooth muscle tissue development." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:14709716] is_a: GO:1901861 ! regulation of muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048745 ! smooth muscle tissue development relationship: regulates GO:0048745 ! smooth muscle tissue development created_by: bhm creation_date: 2017-02-01T14:31:16Z [Term] id: GO:1905900 name: negative regulation of smooth muscle tissue development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle tissue development." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:14709716] synonym: "down regulation of smooth muscle tissue development" EXACT [GOC:TermGenie] synonym: "down-regulation of smooth muscle tissue development" EXACT [GOC:TermGenie] synonym: "downregulation of smooth muscle tissue development" EXACT [GOC:TermGenie] synonym: "inhibition of smooth muscle tissue development" NARROW [GOC:TermGenie] is_a: GO:1901862 ! negative regulation of muscle tissue development is_a: GO:1905899 ! regulation of smooth muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048745 ! smooth muscle tissue development relationship: negatively_regulates GO:0048745 ! smooth muscle tissue development created_by: bhm creation_date: 2017-02-01T14:31:24Z [Term] id: GO:1905901 name: positive regulation of smooth muscle tissue development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of smooth muscle tissue development." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:14709716] synonym: "activation of smooth muscle tissue development" NARROW [GOC:TermGenie] synonym: "up regulation of smooth muscle tissue development" EXACT [GOC:TermGenie] synonym: "up-regulation of smooth muscle tissue development" EXACT [GOC:TermGenie] synonym: "upregulation of smooth muscle tissue development" EXACT [GOC:TermGenie] is_a: GO:1901863 ! positive regulation of muscle tissue development is_a: GO:1905899 ! regulation of smooth muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048745 ! smooth muscle tissue development relationship: positively_regulates GO:0048745 ! smooth muscle tissue development created_by: bhm creation_date: 2017-02-01T14:31:33Z [Term] id: GO:1905902 name: regulation of mesoderm formation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mesoderm formation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23939491] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001707 ! mesoderm formation relationship: regulates GO:0001707 ! mesoderm formation created_by: rph creation_date: 2017-02-03T12:28:20Z [Term] id: GO:1905903 name: negative regulation of mesoderm formation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm formation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23939491] synonym: "down regulation of mesoderm formation" EXACT [GOC:TermGenie] synonym: "down-regulation of mesoderm formation" EXACT [GOC:TermGenie] synonym: "downregulation of mesoderm formation" EXACT [GOC:TermGenie] synonym: "inhibition of mesoderm formation" NARROW [GOC:TermGenie] is_a: GO:1905902 ! regulation of mesoderm formation is_a: GO:2000381 ! negative regulation of mesoderm development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001707 ! mesoderm formation relationship: negatively_regulates GO:0001707 ! mesoderm formation created_by: rph creation_date: 2017-02-03T12:28:29Z [Term] id: GO:1905904 name: positive regulation of mesoderm formation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mesoderm formation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23939491] synonym: "activation of mesoderm formation" NARROW [GOC:TermGenie] synonym: "up regulation of mesoderm formation" EXACT [GOC:TermGenie] synonym: "up-regulation of mesoderm formation" EXACT [GOC:TermGenie] synonym: "upregulation of mesoderm formation" EXACT [GOC:TermGenie] is_a: GO:1905902 ! regulation of mesoderm formation is_a: GO:2000382 ! positive regulation of mesoderm development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001707 ! mesoderm formation relationship: positively_regulates GO:0001707 ! mesoderm formation created_by: rph creation_date: 2017-02-03T12:28:38Z [Term] id: GO:1905921 name: regulation of acetylcholine biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of acetylcholine biosynthetic process." [GO_REF:0000058, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:20164328] synonym: "regulation of acetylcholine anabolism" EXACT [GOC:TermGenie] synonym: "regulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] synonym: "regulation of acetylcholine formation" EXACT [GOC:TermGenie] synonym: "regulation of acetylcholine synthesis" EXACT [GOC:TermGenie] is_a: GO:0009889 ! regulation of biosynthetic process is_a: GO:0060408 ! regulation of acetylcholine metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0008292 ! acetylcholine biosynthetic process relationship: regulates GO:0008292 ! acetylcholine biosynthetic process created_by: bc creation_date: 2017-02-08T13:08:30Z [Term] id: GO:1905922 name: negative regulation of acetylcholine biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of acetylcholine biosynthetic process." [GO_REF:0000058, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:20164328] synonym: "down regulation of acetylcholine anabolism" EXACT [GOC:TermGenie] synonym: "down regulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] synonym: "down regulation of acetylcholine biosynthetic process" EXACT [GOC:TermGenie] synonym: "down regulation of acetylcholine formation" EXACT [GOC:TermGenie] synonym: "down regulation of acetylcholine synthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of acetylcholine anabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of acetylcholine biosynthetic process" EXACT [GOC:TermGenie] synonym: "down-regulation of acetylcholine formation" EXACT [GOC:TermGenie] synonym: "down-regulation of acetylcholine synthesis" EXACT [GOC:TermGenie] synonym: "downregulation of acetylcholine anabolism" EXACT [GOC:TermGenie] synonym: "downregulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] synonym: "downregulation of acetylcholine biosynthetic process" EXACT [GOC:TermGenie] synonym: "downregulation of acetylcholine formation" EXACT [GOC:TermGenie] synonym: "downregulation of acetylcholine synthesis" EXACT [GOC:TermGenie] synonym: "inhibition of acetylcholine anabolism" NARROW [GOC:TermGenie] synonym: "inhibition of acetylcholine biosynthesis" NARROW [GOC:TermGenie] synonym: "inhibition of acetylcholine biosynthetic process" NARROW [GOC:TermGenie] synonym: "inhibition of acetylcholine formation" NARROW [GOC:TermGenie] synonym: "inhibition of acetylcholine synthesis" NARROW [GOC:TermGenie] synonym: "negative regulation of acetylcholine anabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] synonym: "negative regulation of acetylcholine formation" EXACT [GOC:TermGenie] synonym: "negative regulation of acetylcholine synthesis" EXACT [GOC:TermGenie] is_a: GO:0009890 ! negative regulation of biosynthetic process is_a: GO:0060410 ! negative regulation of acetylcholine metabolic process is_a: GO:1905921 ! regulation of acetylcholine biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0008292 ! acetylcholine biosynthetic process relationship: negatively_regulates GO:0008292 ! acetylcholine biosynthetic process created_by: bc creation_date: 2017-02-08T13:08:39Z [Term] id: GO:1905923 name: positive regulation of acetylcholine biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of acetylcholine biosynthetic process." [GO_REF:0000058, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:20164328] synonym: "activation of acetylcholine anabolism" NARROW [GOC:TermGenie] synonym: "activation of acetylcholine biosynthesis" NARROW [GOC:TermGenie] synonym: "activation of acetylcholine biosynthetic process" NARROW [GOC:TermGenie] synonym: "activation of acetylcholine formation" NARROW [GOC:TermGenie] synonym: "activation of acetylcholine synthesis" NARROW [GOC:TermGenie] synonym: "positive regulation of acetylcholine anabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] synonym: "positive regulation of acetylcholine formation" EXACT [GOC:TermGenie] synonym: "positive regulation of acetylcholine synthesis" EXACT [GOC:TermGenie] synonym: "up regulation of acetylcholine anabolism" EXACT [GOC:TermGenie] synonym: "up regulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] synonym: "up regulation of acetylcholine biosynthetic process" EXACT [GOC:TermGenie] synonym: "up regulation of acetylcholine formation" EXACT [GOC:TermGenie] synonym: "up regulation of acetylcholine synthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of acetylcholine anabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of acetylcholine biosynthetic process" EXACT [GOC:TermGenie] synonym: "up-regulation of acetylcholine formation" EXACT [GOC:TermGenie] synonym: "up-regulation of acetylcholine synthesis" EXACT [GOC:TermGenie] synonym: "upregulation of acetylcholine anabolism" EXACT [GOC:TermGenie] synonym: "upregulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] synonym: "upregulation of acetylcholine biosynthetic process" EXACT [GOC:TermGenie] synonym: "upregulation of acetylcholine formation" EXACT [GOC:TermGenie] synonym: "upregulation of acetylcholine synthesis" EXACT [GOC:TermGenie] is_a: GO:0009891 ! positive regulation of biosynthetic process is_a: GO:0060409 ! positive regulation of acetylcholine metabolic process is_a: GO:1905921 ! regulation of acetylcholine biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0008292 ! acetylcholine biosynthetic process relationship: positively_regulates GO:0008292 ! acetylcholine biosynthetic process created_by: bc creation_date: 2017-02-08T13:08:48Z [Term] id: GO:1905936 name: regulation of germ cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of germ cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:15342467] is_a: GO:0042127 ! regulation of cell population proliferation is_a: GO:0051239 ! regulation of multicellular organismal process is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0036093 ! germ cell proliferation relationship: regulates GO:0036093 ! germ cell proliferation created_by: hbye creation_date: 2017-02-09T14:51:31Z [Term] id: GO:1905937 name: negative regulation of germ cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of germ cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:15342467] synonym: "down regulation of germ cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of germ cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of germ cell proliferation" EXACT [GOC:TermGenie] synonym: "inhibition of germ cell proliferation" NARROW [GOC:TermGenie] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1905936 ! regulation of germ cell proliferation is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0036093 ! germ cell proliferation relationship: negatively_regulates GO:0036093 ! germ cell proliferation created_by: hbye creation_date: 2017-02-09T14:51:41Z [Term] id: GO:1905938 name: positive regulation of germ cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of germ cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:15342467] synonym: "activation of germ cell proliferation" NARROW [GOC:TermGenie] synonym: "up regulation of germ cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of germ cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of germ cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1905936 ! regulation of germ cell proliferation is_a: GO:2000243 ! positive regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0036093 ! germ cell proliferation relationship: positively_regulates GO:0036093 ! germ cell proliferation created_by: hbye creation_date: 2017-02-09T14:51:51Z [Term] id: GO:1905939 name: regulation of gonad development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of gonad development." [GO_REF:0000058, GOC:TermGenie, PMID:15342467] synonym: "regulation of gonadogenesis" EXACT [GOC:TermGenie] is_a: GO:0050793 ! regulation of developmental process is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0008406 ! gonad development relationship: regulates GO:0008406 ! gonad development created_by: hbye creation_date: 2017-02-09T17:01:50Z [Term] id: GO:1905940 name: negative regulation of gonad development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of gonad development." [GO_REF:0000058, GOC:TermGenie, PMID:15342467] synonym: "down regulation of gonad development" EXACT [GOC:TermGenie] synonym: "down regulation of gonadogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of gonad development" EXACT [GOC:TermGenie] synonym: "down-regulation of gonadogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of gonad development" EXACT [GOC:TermGenie] synonym: "downregulation of gonadogenesis" EXACT [GOC:TermGenie] synonym: "inhibition of gonad development" NARROW [GOC:TermGenie] synonym: "inhibition of gonadogenesis" NARROW [GOC:TermGenie] synonym: "negative regulation of gonadogenesis" EXACT [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1905939 ! regulation of gonad development is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0008406 ! gonad development relationship: negatively_regulates GO:0008406 ! gonad development created_by: hbye creation_date: 2017-02-09T17:01:59Z [Term] id: GO:1905941 name: positive regulation of gonad development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of gonad development." [GO_REF:0000058, GOC:TermGenie, PMID:15342467] synonym: "activation of gonad development" NARROW [GOC:TermGenie] synonym: "activation of gonadogenesis" NARROW [GOC:TermGenie] synonym: "positive regulation of gonadogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of gonad development" EXACT [GOC:TermGenie] synonym: "up regulation of gonadogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of gonad development" EXACT [GOC:TermGenie] synonym: "up-regulation of gonadogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of gonad development" EXACT [GOC:TermGenie] synonym: "upregulation of gonadogenesis" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1905939 ! regulation of gonad development is_a: GO:2000243 ! positive regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0008406 ! gonad development relationship: positively_regulates GO:0008406 ! gonad development created_by: hbye creation_date: 2017-02-09T17:02:08Z [Term] id: GO:1905952 name: regulation of lipid localization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of lipid localization." [GO_REF:0000058, GOC:TermGenie, PMID:17564681] synonym: "regulation of lipid localisation" EXACT [GOC:TermGenie] is_a: GO:0032879 ! regulation of localization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0010876 ! lipid localization relationship: regulates GO:0010876 ! lipid localization created_by: rz creation_date: 2017-02-21T12:12:22Z [Term] id: GO:1905953 name: negative regulation of lipid localization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of lipid localization." [GO_REF:0000058, GOC:TermGenie, PMID:17564681] synonym: "down regulation of lipid localisation" EXACT [GOC:TermGenie] synonym: "down regulation of lipid localization" EXACT [GOC:TermGenie] synonym: "down-regulation of lipid localisation" EXACT [GOC:TermGenie] synonym: "down-regulation of lipid localization" EXACT [GOC:TermGenie] synonym: "downregulation of lipid localisation" EXACT [GOC:TermGenie] synonym: "downregulation of lipid localization" EXACT [GOC:TermGenie] synonym: "inhibition of lipid localisation" NARROW [GOC:TermGenie] synonym: "inhibition of lipid localization" NARROW [GOC:TermGenie] synonym: "negative regulation of lipid localisation" EXACT [GOC:TermGenie] is_a: GO:0048519 ! negative regulation of biological process is_a: GO:1905952 ! regulation of lipid localization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0010876 ! lipid localization relationship: negatively_regulates GO:0010876 ! lipid localization created_by: rz creation_date: 2017-02-21T12:12:41Z [Term] id: GO:1905954 name: positive regulation of lipid localization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of lipid localization." [GO_REF:0000058, GOC:TermGenie, PMID:17564681] synonym: "activation of lipid localisation" NARROW [GOC:TermGenie] synonym: "activation of lipid localization" NARROW [GOC:TermGenie] synonym: "positive regulation of lipid localisation" EXACT [GOC:TermGenie] synonym: "up regulation of lipid localisation" EXACT [GOC:TermGenie] synonym: "up regulation of lipid localization" EXACT [GOC:TermGenie] synonym: "up-regulation of lipid localisation" EXACT [GOC:TermGenie] synonym: "up-regulation of lipid localization" EXACT [GOC:TermGenie] synonym: "upregulation of lipid localisation" EXACT [GOC:TermGenie] synonym: "upregulation of lipid localization" EXACT [GOC:TermGenie] is_a: GO:0048518 ! positive regulation of biological process is_a: GO:1905952 ! regulation of lipid localization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0010876 ! lipid localization relationship: positively_regulates GO:0010876 ! lipid localization created_by: rz creation_date: 2017-02-21T12:12:49Z [Term] id: GO:1905955 name: negative regulation of endothelial tube morphogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of endothelial tube morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:25961718] synonym: "down regulation of endothelial tube morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of endothelial tube morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of endothelial tube morphogenesis" EXACT [GOC:TermGenie] synonym: "inhibition of endothelial tube morphogenesis" NARROW [GOC:TermGenie] is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1901509 ! regulation of endothelial tube morphogenesis is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0061154 ! endothelial tube morphogenesis relationship: negatively_regulates GO:0061154 ! endothelial tube morphogenesis created_by: rph creation_date: 2017-02-21T15:17:31Z [Term] id: GO:1905956 name: positive regulation of endothelial tube morphogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of endothelial tube morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:25961718] synonym: "activation of endothelial tube morphogenesis" NARROW [GOC:TermGenie] synonym: "up regulation of endothelial tube morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of endothelial tube morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of endothelial tube morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1901509 ! regulation of endothelial tube morphogenesis is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0061154 ! endothelial tube morphogenesis relationship: positively_regulates GO:0061154 ! endothelial tube morphogenesis created_by: rph creation_date: 2017-02-21T15:17:39Z [Term] id: GO:1990009 name: retinal cell apoptotic process namespace: biological_process alt_id: GO:0046674 def: "Any apoptotic process in a retinal cell." [GOC:mtg_apoptosis, PMID:15558487, PMID:24664675] synonym: "induction of retinal programmed cell death" RELATED [] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0009004 ! retinal cell relationship: occurs_in CL:0009004 ! retinal cell created_by: pr creation_date: 2012-12-12T10:15:08Z [Term] id: GO:1990010 name: compound eye retinal cell apoptotic process namespace: biological_process def: "Any apoptotic process in a compound eye retinal cell." [GOC:mtg_apoptosis, PMID:12021768] is_a: GO:1990009 ! retinal cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0009001 ! compound eye retinal cell relationship: occurs_in CL:0009001 ! compound eye retinal cell created_by: pr creation_date: 2012-12-12T10:21:07Z [Term] id: GO:1990182 name: exosomal secretion namespace: biological_process def: "The process whereby a membrane-bounded vesicle is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane." [GOC:hjd, PMID:10572093, PMID:12154376, PMID:16773132, PMID:18617898] synonym: "exosomal protein secretion" NARROW [PMID:18617898] synonym: "exosomal secretory pathway" EXACT [PMID:18617898] synonym: "extracellular vesicular exosome secretion" EXACT [GOC:hjd] synonym: "multi-vesicular body fusion with plasma membrane" EXACT [] synonym: "secretion of exosome" EXACT [PMID:18617898] is_a: GO:0006887 ! exocytosis is_a: GO:0051650 ! establishment of vesicle localization intersection_of: GO:0006887 ! exocytosis intersection_of: has_primary_input GO:0070062 ! extracellular exosome relationship: has_primary_input GO:0070062 ! extracellular exosome relationship: part_of GO:0097734 ! extracellular exosome biogenesis property_value: RO:0002161 NCBITaxon:4890 created_by: hjd creation_date: 2013-09-04T21:08:14Z [Term] id: GO:1990234 name: transferase complex namespace: cellular_component def: "A protein complex capable of catalyzing the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor)." [GOC:bhm, PMID:16540464] is_a: GO:1902494 ! catalytic complex intersection_of: GO:1902494 ! catalytic complex intersection_of: capable_of GO:0016740 ! transferase activity relationship: capable_of GO:0016740 ! transferase activity created_by: bhm creation_date: 2013-11-12T13:20:12Z [Term] id: GO:1990280 name: RNA localization to chromatin namespace: biological_process def: "A process in which RNA is transported to and maintained in a part of a chromosome that is organized into chromatin." [GOC:dos, GOC:mah, PMID:22582262] synonym: "RNA localisation to chromatin" EXACT [] is_a: GO:0006403 ! RNA localization intersection_of: GO:0006403 ! RNA localization intersection_of: has_target_end_location GO:0000785 ! chromatin relationship: has_target_end_location GO:0000785 ! chromatin created_by: mah creation_date: 2014-01-30T15:55:34Z [Term] id: GO:1990351 name: transporter complex namespace: cellular_component def: "A protein complex facilitating transport of molecules (proteins, small molecules, nucleic acids) into, out of or within a cell, or between cells." [GOC:bhm, PMID:15449578] comment: An example of this is GTR1 in human (UniProt symbol P11166) in PMID:15449578 (inferred from direct assay). is_a: GO:0032991 ! protein-containing complex intersection_of: GO:0032991 ! protein-containing complex intersection_of: capable_of GO:0005215 ! transporter activity relationship: capable_of GO:0005215 ! transporter activity created_by: bhm creation_date: 2014-03-26T14:23:27Z [Term] id: GO:1990375 name: baculum development namespace: biological_process def: "The reproductive developmental process whose specific outcome is the progression of the baculum over time, from its formation to the mature structure." [GOC:sl, PMID:21471296] synonym: "os penis development" EXACT [GOC:sl] synonym: "penile bone development" EXACT [GOC:sl] synonym: "penis bone development" EXACT [GOC:sl] is_a: GO:0048608 ! reproductive structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0006435 ! os penis relationship: results_in_development_of UBERON:0006435 ! os penis created_by: sl creation_date: 2014-05-01T23:59:13Z [Term] id: GO:1990502 name: dense core granule maturation namespace: biological_process def: "Steps required to transform a dense core granule generated at the trans-Golgi network into a fully formed and transmissible dense core granule. Dense core granule maturation proceeds through clathrin-mediated membrane remodeling events and is essential for efficient processing of cargo within dense core granules as well as for removing factors that might otherwise interfere with dense core granule trafficking and exocytosis." [GOC:kmv, PMID:22654674] synonym: "dense core vesicle maturation" EXACT [] is_a: GO:0061792 ! secretory granule maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of GO:0031045 ! dense core granule relationship: results_in_maturation_of GO:0031045 ! dense core granule created_by: kmv creation_date: 2014-09-30T20:35:11Z [Term] id: GO:1990705 name: cholangiocyte proliferation namespace: biological_process def: "The multiplication or reproduction of cholangiocytes, resulting in the expansion of the cholangiocyte population. A cholangiocyte is an epithelial cell that is part of the bile duct. Cholangiocytes contribute to bile secretion via net release of bicarbonate and water." [PMID:24434010] synonym: "hepatoblast proliferation" EXACT [] is_a: GO:0050673 ! epithelial cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:1000488 ! cholangiocyte relationship: acts_on_population_of CL:1000488 ! cholangiocyte creation_date: 2015-03-16T23:23:50Z [Term] id: GO:1990748 name: cellular detoxification namespace: biological_process def: "Any process carried out at the cellular level that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance." [GOC:vw] is_a: GO:0009987 ! cellular process is_a: GO:0098754 ! detoxification intersection_of: GO:0098754 ! detoxification intersection_of: occurs_in CL:0000000 ! cell relationship: occurs_in CL:0000000 ! cell relationship: part_of GO:0097237 ! cellular response to toxic substance created_by: vw creation_date: 2015-05-18T16:17:46Z [Term] id: GO:1990765 name: colon smooth muscle contraction namespace: biological_process def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry of the large intestine, exclusive of the rectum. The colon is that part of the large intestine that connects the small intestine to the rectum." [PMID:24170253] is_a: GO:0006939 ! smooth muscle contraction intersection_of: GO:0006939 ! smooth muscle contraction intersection_of: occurs_in UBERON:0001155 ! colon relationship: in_taxon NCBITaxon:7742 {all_only="true"} ! Vertebrata relationship: occurs_in UBERON:0001155 ! colon relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0014827 ! intestine smooth muscle contraction created_by: sl creation_date: 2015-06-10T18:29:21Z [Term] id: GO:1990768 name: gastric mucosal blood circulation namespace: biological_process def: "The flow of blood through the gastric mucosa of an animal, enabling the transport of nutrients and the removal of waste products." [PMID:10807413] synonym: "stomach mucosal blood circulation" EXACT [] is_a: GO:0008015 ! blood circulation intersection_of: GO:0008015 ! blood circulation intersection_of: occurs_in UBERON:0004786 ! gastrointestinal system mucosa relationship: occurs_in UBERON:0004786 ! gastrointestinal system mucosa created_by: sl creation_date: 2015-06-10T20:11:09Z [Term] id: GO:1990770 name: small intestine smooth muscle contraction namespace: biological_process def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry in the intestine between the stomach and the large intestine." [PMID:11991626] is_a: GO:0006939 ! smooth muscle contraction intersection_of: GO:0006939 ! smooth muscle contraction intersection_of: occurs_in UBERON:0002108 ! small intestine relationship: in_taxon NCBITaxon:7742 {all_only="true"} ! Vertebrata relationship: occurs_in UBERON:0002108 ! small intestine relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0014827 ! intestine smooth muscle contraction created_by: sl creation_date: 2015-06-11T18:02:33Z [Term] id: GO:1990778 name: protein localization to cell periphery namespace: biological_process def: "A process in which a protein is transported to, or maintained in, the cell periphery." [PMID:18216290] is_a: GO:0008104 ! protein localization intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0071944 ! cell periphery relationship: has_target_end_location GO:0071944 ! cell periphery creation_date: 2015-06-18T22:37:39Z [Term] id: GO:1990849 name: vacuolar localization namespace: biological_process def: "Any process in which the vacuole is transported to, and/or maintained in, a specific location within the cell." [PMID:26283797] synonym: "maintenance of vacuolar localization" EXACT [] synonym: "maintenance of vacuolar location" NARROW [] synonym: "maintenance of vacuole localization" EXACT [] synonym: "maintenance of vacuole location" EXACT [] is_a: GO:0051640 ! organelle localization intersection_of: GO:0051179 ! localization intersection_of: has_primary_input GO:0005773 ! vacuole relationship: has_primary_input GO:0005773 ! vacuole property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22182" xsd:anyURI created_by: mcc creation_date: 2015-09-10T08:16:02Z [Term] id: GO:1990863 name: acinar cell proliferation namespace: biological_process def: "The multiplication or reproduction of acinar cells, resulting in the expansion of a cell population. An acinar cell is a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini (singular acinus)." [PMID:9788538] synonym: "acinic cell proliferation" EXACT [] synonym: "acinous cell proliferation" EXACT [] is_a: GO:0050673 ! epithelial cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000622 ! acinar cell relationship: acts_on_population_of CL:0000622 ! acinar cell created_by: sl creation_date: 2015-09-25T14:26:09Z [Term] id: GO:1990874 name: vascular associated smooth muscle cell proliferation namespace: biological_process def: "The multiplication or reproduction of vascular smooth muscle cells, resulting in the expansion of a cell population. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels." [PMID:23246467] synonym: "vascular smooth muscle cell proliferation" EXACT [] synonym: "VSMC proliferation" EXACT [] is_a: GO:0048659 ! smooth muscle cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000359 ! vascular associated smooth muscle cell relationship: acts_on_population_of CL:0000359 ! vascular associated smooth muscle cell created_by: sl creation_date: 2015-09-29T16:34:59Z [Term] id: GO:1990904 name: ribonucleoprotein complex namespace: cellular_component alt_id: GO:0030529 alt_id: GO:1990903 def: "A macromolecular complex that contains both RNA and protein molecules." [GOC:krc, GOC:vesicles] subset: goslim_pir synonym: "extracellular ribonucleoprotein complex" NARROW [] synonym: "intracellular ribonucleoprotein complex" NARROW [] synonym: "protein-RNA complex" EXACT [] synonym: "RNA-protein complex" EXACT [] synonym: "RNP" EXACT [] xref: Wikipedia:Ribonucleoprotein is_a: GO:0032991 ! protein-containing complex relationship: has_part CHEBI:33697 ! ribonucleic acid created_by: pr creation_date: 2015-11-19T12:26:37Z [Term] id: GO:1990917 name: ooplasm namespace: cellular_component def: "The cytoplasm of an ovum." [PMID:19022436] is_a: GO:0005737 ! cytoplasm intersection_of: GO:0005737 ! cytoplasm intersection_of: part_of CL:0000025 ! egg cell relationship: part_of CL:0000025 ! egg cell property_value: RO:0002161 NCBITaxon:4751 created_by: sl creation_date: 2015-12-10T21:40:16Z [Term] id: GO:2000018 name: regulation of male gonad development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of male gonad development." [GOC:obol, GOC:yaf] synonym: "regulation of testicular development" EXACT [GOC:obol] synonym: "regulation of testis development" EXACT [GOC:obol] is_a: GO:1905939 ! regulation of gonad development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0008584 ! male gonad development relationship: regulates GO:0008584 ! male gonad development created_by: jl creation_date: 2010-07-15T03:29:05Z [Term] id: GO:2000019 name: negative regulation of male gonad development namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of male gonad development." [GOC:obol, GOC:yaf] synonym: "negative regulation of testicular development" EXACT [GOC:obol] synonym: "negative regulation of testis development" EXACT [GOC:obol] is_a: GO:1905940 ! negative regulation of gonad development is_a: GO:2000018 ! regulation of male gonad development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0008584 ! male gonad development relationship: negatively_regulates GO:0008584 ! male gonad development created_by: jl creation_date: 2010-07-15T03:29:10Z [Term] id: GO:2000020 name: positive regulation of male gonad development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of male gonad development." [GOC:obol] synonym: "positive regulation of testicular development" EXACT [GOC:obol] synonym: "positive regulation of testis development" EXACT [GOC:obol] is_a: GO:1905941 ! positive regulation of gonad development is_a: GO:2000018 ! regulation of male gonad development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0008584 ! male gonad development relationship: positively_regulates GO:0008584 ! male gonad development created_by: jl creation_date: 2010-07-15T03:29:13Z [Term] id: GO:2000026 name: regulation of multicellular organismal development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of multicellular organismal development." [GOC:obol] is_a: GO:0050793 ! regulation of developmental process is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007275 ! multicellular organism development relationship: regulates GO:0007275 ! multicellular organism development created_by: tb creation_date: 2010-08-05T11:25:59Z [Term] id: GO:2000027 name: regulation of animal organ morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of animal organ morphogenesis." [GOC:obol] synonym: "regulation of histogenesis and organogenesis" RELATED [GOC:obol] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0009887 ! animal organ morphogenesis relationship: regulates GO:0009887 ! animal organ morphogenesis created_by: tb creation_date: 2010-08-05T11:26:27Z [Term] id: GO:2000035 name: regulation of stem cell division namespace: biological_process def: "Any process that modulates the frequency, rate or extent of stem cell division." [GOC:obol] synonym: "regulation of stem cell renewal" EXACT [GOC:obol] is_a: GO:0051302 ! regulation of cell division intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0017145 ! stem cell division relationship: regulates GO:0017145 ! stem cell division created_by: tb creation_date: 2010-08-05T11:34:53Z [Term] id: GO:2000036 name: regulation of stem cell population maintenance namespace: biological_process def: "Any process that modulates the frequency, rate or extent of stem cell population maintenance." [GOC:obol] synonym: "regulation of maintenance of pluripotency" RELATED [GOC:obol] is_a: GO:0050793 ! regulation of developmental process is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0019827 ! stem cell population maintenance relationship: regulates GO:0019827 ! stem cell population maintenance created_by: tb creation_date: 2010-08-05T11:35:25Z [Term] id: GO:2000061 name: regulation of ureter smooth muscle cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of ureter smooth muscle cell differentiation." [GOC:mtg_kidney_jan10, GOC:obol, GOC:yaf] is_a: GO:0048634 ! regulation of muscle organ development is_a: GO:0051150 ! regulation of smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0072193 ! ureter smooth muscle cell differentiation relationship: regulates GO:0072193 ! ureter smooth muscle cell differentiation created_by: jl creation_date: 2010-08-20T01:44:16Z [Term] id: GO:2000062 name: negative regulation of ureter smooth muscle cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of ureter smooth muscle cell differentiation." [GOC:mtg_kidney_jan10, GOC:obol, GOC:yaf] is_a: GO:0051151 ! negative regulation of smooth muscle cell differentiation is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:2000061 ! regulation of ureter smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0072193 ! ureter smooth muscle cell differentiation relationship: negatively_regulates GO:0072193 ! ureter smooth muscle cell differentiation created_by: jl creation_date: 2010-08-20T01:44:23Z [Term] id: GO:2000063 name: positive regulation of ureter smooth muscle cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of ureter smooth muscle cell differentiation." [GOC:mtg_kidney_jan10, GOC:obol, GOC:yaf] is_a: GO:0051152 ! positive regulation of smooth muscle cell differentiation is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:2000061 ! regulation of ureter smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0072193 ! ureter smooth muscle cell differentiation relationship: positively_regulates GO:0072193 ! ureter smooth muscle cell differentiation created_by: jl creation_date: 2010-08-20T01:44:28Z [Term] id: GO:2000068 name: regulation of defense response to insect namespace: biological_process def: "Any process that modulates the frequency, rate or extent of defense response to insect." [GOC:obol] synonym: "regulation of physiological defense response to insect" EXACT [GOC:obol] is_a: GO:0031347 ! regulation of defense response intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002213 ! defense response to insect relationship: regulates GO:0002213 ! defense response to insect created_by: tb creation_date: 2010-08-23T09:30:00Z [Term] id: GO:2000074 name: regulation of type B pancreatic cell development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of pancreatic B cell development." [GOC:obol, GOC:yaf] synonym: "regulation of pancreatic B cell development" EXACT [GOC:mah] synonym: "regulation of pancreatic beta cell development" EXACT [GOC:obol] is_a: GO:0060284 ! regulation of cell development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003323 ! type B pancreatic cell development relationship: regulates GO:0003323 ! type B pancreatic cell development created_by: tb creation_date: 2010-08-27T11:19:37Z [Term] id: GO:2000077 name: negative regulation of type B pancreatic cell development namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic B cell development." [GOC:obol, GOC:yaf] synonym: "negative regulation of pancreatic B cell development" EXACT [GOC:mah] synonym: "negative regulation of pancreatic beta cell development" EXACT [GOC:obol] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:2000074 ! regulation of type B pancreatic cell development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0003323 ! type B pancreatic cell development relationship: negatively_regulates GO:0003323 ! type B pancreatic cell development created_by: tb creation_date: 2010-08-27T11:21:17Z [Term] id: GO:2000078 name: positive regulation of type B pancreatic cell development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of pancreatic B cell development." [GOC:obol, GOC:yaf] synonym: "positive regulation of pancreatic B cell development" EXACT [GOC:mah] synonym: "positive regulation of pancreatic beta cell development" EXACT [GOC:obol] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0030858 ! positive regulation of epithelial cell differentiation is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:2000074 ! regulation of type B pancreatic cell development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0003323 ! type B pancreatic cell development relationship: positively_regulates GO:0003323 ! type B pancreatic cell development created_by: tb creation_date: 2010-08-27T11:21:19Z [Term] id: GO:2000084 name: regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis." [GOC:mtg_kidney_jan10] synonym: "regulation of mesonephric mesenchyme to epithelial transition" RELATED [GOC:obol] is_a: GO:2000696 ! regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0061261 ! mesenchymal to epithelial transition involved in mesonephros morphogenesis relationship: regulates GO:0061261 ! mesenchymal to epithelial transition involved in mesonephros morphogenesis created_by: dph creation_date: 2010-09-03T06:06:41Z [Term] id: GO:2000085 name: negative regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis." [GOC:mtg_kidney_jan10] synonym: "negative regulation of mesonephric mesenchyme to epithelial transition" RELATED [GOC:obol] is_a: GO:2000084 ! regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis is_a: GO:2000697 ! negative regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0061261 ! mesenchymal to epithelial transition involved in mesonephros morphogenesis relationship: negatively_regulates GO:0061261 ! mesenchymal to epithelial transition involved in mesonephros morphogenesis created_by: dph creation_date: 2010-09-03T06:08:21Z [Term] id: GO:2000086 name: positive regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis." [GOC:mtg_kidney_jan10] synonym: "positive regulation of mesonephric mesenchyme to epithelial transition" RELATED [GOC:obol] is_a: GO:2000084 ! regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis is_a: GO:2000698 ! positive regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0061261 ! mesenchymal to epithelial transition involved in mesonephros morphogenesis relationship: positively_regulates GO:0061261 ! mesenchymal to epithelial transition involved in mesonephros morphogenesis created_by: dph creation_date: 2010-09-03T06:08:24Z [Term] id: GO:2000106 name: regulation of leukocyte apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of leukocyte apoptotic process." [GOC:BHF, GOC:mtg_apoptosis] synonym: "regulation of leukocyte apoptosis" NARROW [] is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0071887 ! leukocyte apoptotic process relationship: regulates GO:0071887 ! leukocyte apoptotic process created_by: mah creation_date: 2010-09-15T01:42:05Z [Term] id: GO:2000107 name: negative regulation of leukocyte apoptotic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte apoptotic process." [GOC:BHF, GOC:mtg_apoptosis] synonym: "negative regulation of leukocyte apoptosis" NARROW [] is_a: GO:0043066 ! negative regulation of apoptotic process is_a: GO:2000106 ! regulation of leukocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0071887 ! leukocyte apoptotic process relationship: negatively_regulates GO:0071887 ! leukocyte apoptotic process created_by: mah creation_date: 2010-09-15T01:42:09Z [Term] id: GO:2000108 name: positive regulation of leukocyte apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of leukocyte apoptotic process." [GOC:BHF, GOC:mtg_apoptosis] synonym: "positive regulation of leukocyte apoptosis" NARROW [] is_a: GO:0043065 ! positive regulation of apoptotic process is_a: GO:2000106 ! regulation of leukocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0071887 ! leukocyte apoptotic process relationship: positively_regulates GO:0071887 ! leukocyte apoptotic process created_by: mah creation_date: 2010-09-15T01:42:12Z [Term] id: GO:2000114 name: regulation of establishment of cell polarity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of establishment of cell polarity." [GOC:dph] synonym: "regulation of bud site selection/establishment of cell polarity" RELATED [GOC:obol] synonym: "regulation of cell polarization" EXACT [GOC:obol] is_a: GO:0032878 ! regulation of establishment or maintenance of cell polarity intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030010 ! establishment of cell polarity relationship: regulates GO:0030010 ! establishment of cell polarity created_by: dph creation_date: 2010-09-16T01:22:36Z [Term] id: GO:2000136 name: regulation of cell proliferation involved in heart morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell proliferation involved in heart morphogenesis." [GOC:dph] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0061323 ! cell proliferation involved in heart morphogenesis relationship: regulates GO:0061323 ! cell proliferation involved in heart morphogenesis created_by: dph creation_date: 2010-09-29T12:43:53Z [Term] id: GO:2000137 name: negative regulation of cell proliferation involved in heart morphogenesis namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell proliferation involved in heart morphogenesis." [GOC:dph] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:2000136 ! regulation of cell proliferation involved in heart morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0061323 ! cell proliferation involved in heart morphogenesis relationship: negatively_regulates GO:0061323 ! cell proliferation involved in heart morphogenesis created_by: dph creation_date: 2010-09-29T12:43:55Z [Term] id: GO:2000138 name: positive regulation of cell proliferation involved in heart morphogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell proliferation involved in heart morphogenesis." [GOC:dph] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:2000136 ! regulation of cell proliferation involved in heart morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0061323 ! cell proliferation involved in heart morphogenesis relationship: positively_regulates GO:0061323 ! cell proliferation involved in heart morphogenesis created_by: dph creation_date: 2010-09-29T12:43:57Z [Term] id: GO:2000145 name: regulation of cell motility namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell motility." [GOC:mah] synonym: "regulation of cell locomotion" EXACT [GOC:obol] synonym: "regulation of cell movement" RELATED [GOC:obol] synonym: "regulation of movement of a cell" EXACT [GOC:obol] is_a: GO:0040012 ! regulation of locomotion is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048870 ! cell motility relationship: regulates GO:0048870 ! cell motility created_by: mah creation_date: 2010-10-01T09:41:21Z [Term] id: GO:2000146 name: negative regulation of cell motility namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell motility." [GOC:mah] synonym: "negative regulation of cell locomotion" EXACT [GOC:obol] synonym: "negative regulation of cell movement" RELATED [GOC:obol] synonym: "negative regulation of movement of a cell" EXACT [GOC:obol] is_a: GO:0040013 ! negative regulation of locomotion is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:2000145 ! regulation of cell motility intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048870 ! cell motility relationship: negatively_regulates GO:0048870 ! cell motility created_by: mah creation_date: 2010-10-01T09:41:26Z [Term] id: GO:2000147 name: positive regulation of cell motility namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell motility." [GOC:mah] synonym: "positive regulation of cell locomotion" EXACT [GOC:obol] synonym: "positive regulation of cell movement" RELATED [GOC:obol] synonym: "positive regulation of movement of a cell" EXACT [GOC:obol] is_a: GO:0040017 ! positive regulation of locomotion is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:2000145 ! regulation of cell motility intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048870 ! cell motility relationship: positively_regulates GO:0048870 ! cell motility created_by: mah creation_date: 2010-10-01T09:41:30Z [Term] id: GO:2000155 name: positive regulation of cilium-dependent cell motility namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cilium-dependent cell motility." [GOC:cilia, GOC:jl] synonym: "positive regulation of ciliary cell motility" RELATED [] is_a: GO:1902019 ! regulation of cilium-dependent cell motility is_a: GO:2000147 ! positive regulation of cell motility intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060285 ! cilium-dependent cell motility relationship: positively_regulates GO:0060285 ! cilium-dependent cell motility created_by: mah creation_date: 2010-10-04T12:41:05Z [Term] id: GO:2000172 name: regulation of branching morphogenesis of a nerve namespace: biological_process def: "Any process that modulates the frequency, rate or extent of branching morphogenesis of a nerve." [GOC:BHF] is_a: GO:0060688 ! regulation of morphogenesis of a branching structure intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048755 ! branching morphogenesis of a nerve relationship: regulates GO:0048755 ! branching morphogenesis of a nerve created_by: rl creation_date: 2010-10-07T12:07:54Z [Term] id: GO:2000173 name: negative regulation of branching morphogenesis of a nerve namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of branching morphogenesis of a nerve." [GOC:BHF] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:2000172 ! regulation of branching morphogenesis of a nerve intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048755 ! branching morphogenesis of a nerve relationship: negatively_regulates GO:0048755 ! branching morphogenesis of a nerve created_by: rl creation_date: 2010-10-07T12:07:56Z [Term] id: GO:2000174 name: regulation of pro-T cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of pro-T cell differentiation." [GOC:BHF] synonym: "regulation of pro-T lymphocyte differentiation" EXACT [GOC:obol] is_a: GO:0045580 ! regulation of T cell differentiation is_a: GO:1905456 ! regulation of lymphoid progenitor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002572 ! pro-T cell differentiation relationship: regulates GO:0002572 ! pro-T cell differentiation created_by: mah creation_date: 2010-10-11T10:24:30Z [Term] id: GO:2000175 name: negative regulation of pro-T cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of pro-T cell differentiation." [GOC:BHF] synonym: "negative regulation of pro-T lymphocyte differentiation" EXACT [GOC:obol] is_a: GO:0045581 ! negative regulation of T cell differentiation is_a: GO:1905457 ! negative regulation of lymphoid progenitor cell differentiation is_a: GO:2000174 ! regulation of pro-T cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002572 ! pro-T cell differentiation relationship: negatively_regulates GO:0002572 ! pro-T cell differentiation created_by: mah creation_date: 2010-10-11T10:24:33Z [Term] id: GO:2000176 name: positive regulation of pro-T cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of pro-T cell differentiation." [GOC:BHF] synonym: "positive regulation of pro-T lymphocyte differentiation" EXACT [GOC:obol] is_a: GO:0045582 ! positive regulation of T cell differentiation is_a: GO:1905458 ! positive regulation of lymphoid progenitor cell differentiation is_a: GO:2000174 ! regulation of pro-T cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002572 ! pro-T cell differentiation relationship: positively_regulates GO:0002572 ! pro-T cell differentiation created_by: mah creation_date: 2010-10-11T10:24:35Z [Term] id: GO:2000177 name: regulation of neural precursor cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of neural precursor cell proliferation." [GOC:dph, GOC:yaf] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0061351 ! neural precursor cell proliferation relationship: regulates GO:0061351 ! neural precursor cell proliferation created_by: dph creation_date: 2010-10-13T12:40:41Z [Term] id: GO:2000178 name: negative regulation of neural precursor cell proliferation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of neural precursor cell proliferation." [GOC:dph, GOC:yaf] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:2000177 ! regulation of neural precursor cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0061351 ! neural precursor cell proliferation relationship: negatively_regulates GO:0061351 ! neural precursor cell proliferation created_by: dph creation_date: 2010-10-13T12:40:43Z [Term] id: GO:2000179 name: positive regulation of neural precursor cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of neural precursor cell proliferation." [GOC:dph, GOC:yaf] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:2000177 ! regulation of neural precursor cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0061351 ! neural precursor cell proliferation relationship: positively_regulates GO:0061351 ! neural precursor cell proliferation created_by: dph creation_date: 2010-10-13T12:40:45Z [Term] id: GO:2000181 name: negative regulation of blood vessel morphogenesis namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis." [GOC:dph, GOC:yaf] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis is_a: GO:1901343 ! negative regulation of vasculature development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048514 ! blood vessel morphogenesis relationship: negatively_regulates GO:0048514 ! blood vessel morphogenesis created_by: dph creation_date: 2010-10-13T12:46:31Z [Term] id: GO:2000185 name: regulation of phosphate transmembrane transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of phosphate transmembrane transport." [GOC:obol] synonym: "regulation of phosphate membrane transport" EXACT [] is_a: GO:0010966 ! regulation of phosphate transport is_a: GO:1903795 ! regulation of inorganic anion transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0035435 ! phosphate ion transmembrane transport relationship: regulates GO:0035435 ! phosphate ion transmembrane transport created_by: vw creation_date: 2010-10-15T11:33:04Z [Term] id: GO:2000186 name: negative regulation of phosphate transmembrane transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of phosphate transmembrane transport." [GOC:obol] synonym: "negative regulation of phosphate membrane transport" EXACT [] is_a: GO:1903796 ! negative regulation of inorganic anion transmembrane transport is_a: GO:2000185 ! regulation of phosphate transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0035435 ! phosphate ion transmembrane transport relationship: negatively_regulates GO:0035435 ! phosphate ion transmembrane transport created_by: vw creation_date: 2010-10-15T11:33:08Z [Term] id: GO:2000187 name: positive regulation of phosphate transmembrane transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of phosphate transmembrane transport." [GOC:obol] synonym: "positive regulation of phosphate membrane transport" EXACT [] is_a: GO:1903797 ! positive regulation of inorganic anion transmembrane transport is_a: GO:2000185 ! regulation of phosphate transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0035435 ! phosphate ion transmembrane transport relationship: positively_regulates GO:0035435 ! phosphate ion transmembrane transport created_by: vw creation_date: 2010-10-15T11:33:10Z [Term] id: GO:2000194 name: regulation of female gonad development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of female gonad development." [GOC:obol] synonym: "regulation of ovarian development" EXACT [GOC:obol] synonym: "regulation of ovary development" EXACT [GOC:obol] is_a: GO:1905939 ! regulation of gonad development is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0008585 ! female gonad development relationship: regulates GO:0008585 ! female gonad development created_by: yaf creation_date: 2010-10-19T10:45:34Z [Term] id: GO:2000195 name: negative regulation of female gonad development namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of female gonad development." [GOC:obol] synonym: "negative regulation of ovarian development" EXACT [GOC:obol] synonym: "negative regulation of ovary development" EXACT [GOC:obol] is_a: GO:1905940 ! negative regulation of gonad development is_a: GO:2000194 ! regulation of female gonad development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0008585 ! female gonad development relationship: negatively_regulates GO:0008585 ! female gonad development created_by: yaf creation_date: 2010-10-19T10:45:38Z [Term] id: GO:2000196 name: positive regulation of female gonad development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of female gonad development." [GOC:obol] synonym: "positive regulation of ovarian development" EXACT [GOC:obol] synonym: "positive regulation of ovary development" EXACT [GOC:obol] is_a: GO:1905941 ! positive regulation of gonad development is_a: GO:2000194 ! regulation of female gonad development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0008585 ! female gonad development relationship: positively_regulates GO:0008585 ! female gonad development created_by: yaf creation_date: 2010-10-19T10:45:41Z [Term] id: GO:2000226 name: regulation of pancreatic A cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of pancreatic A cell differentiation." [GOC:mah] synonym: "regulation of pancreatic alpha cell differentiation" EXACT [GOC:obol] is_a: GO:0030856 ! regulation of epithelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003310 ! pancreatic A cell differentiation relationship: regulates GO:0003310 ! pancreatic A cell differentiation created_by: mah creation_date: 2010-11-09T03:43:37Z [Term] id: GO:2000227 name: negative regulation of pancreatic A cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic A cell differentiation." [GOC:mah] synonym: "negative regulation of pancreatic alpha cell differentiation" EXACT [GOC:obol] is_a: GO:0030857 ! negative regulation of epithelial cell differentiation is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:2000226 ! regulation of pancreatic A cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0003310 ! pancreatic A cell differentiation relationship: negatively_regulates GO:0003310 ! pancreatic A cell differentiation created_by: mah creation_date: 2010-11-09T03:43:40Z [Term] id: GO:2000228 name: positive regulation of pancreatic A cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of pancreatic A cell differentiation." [GOC:mah] synonym: "positive regulation of pancreatic alpha cell differentiation" EXACT [GOC:obol] is_a: GO:0030858 ! positive regulation of epithelial cell differentiation is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:2000226 ! regulation of pancreatic A cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0003310 ! pancreatic A cell differentiation relationship: positively_regulates GO:0003310 ! pancreatic A cell differentiation created_by: mah creation_date: 2010-11-09T03:43:42Z [Term] id: GO:2000241 name: regulation of reproductive process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of reproductive process." [GOC:mah] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0022414 ! reproductive process relationship: regulates GO:0022414 ! reproductive process created_by: mah creation_date: 2010-11-10T02:44:02Z [Term] id: GO:2000242 name: negative regulation of reproductive process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of reproductive process." [GOC:mah] is_a: GO:0048519 ! negative regulation of biological process is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0022414 ! reproductive process relationship: negatively_regulates GO:0022414 ! reproductive process created_by: mah creation_date: 2010-11-10T02:44:05Z [Term] id: GO:2000243 name: positive regulation of reproductive process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of reproductive process." [GOC:mah] is_a: GO:0048518 ! positive regulation of biological process is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0022414 ! reproductive process relationship: positively_regulates GO:0022414 ! reproductive process created_by: mah creation_date: 2010-11-10T02:44:08Z [Term] id: GO:2000248 name: negative regulation of establishment or maintenance of neuroblast polarity namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or maintenance of neuroblast polarity." [GOC:obol] synonym: "negative regulation of establishment and/or maintenance of neuroblast cell polarity" EXACT [GOC:obol] is_a: GO:0010454 ! negative regulation of cell fate commitment is_a: GO:0032878 ! regulation of establishment or maintenance of cell polarity is_a: GO:0045769 ! negative regulation of asymmetric cell division intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0045196 ! establishment or maintenance of neuroblast polarity relationship: negatively_regulates GO:0045196 ! establishment or maintenance of neuroblast polarity created_by: vw creation_date: 2010-11-11T11:40:34Z [Term] id: GO:2000254 name: regulation of male germ cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of male germ cell proliferation." [GOC:obol] is_a: GO:1905936 ! regulation of germ cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002176 ! male germ cell proliferation relationship: regulates GO:0002176 ! male germ cell proliferation created_by: dph creation_date: 2010-11-18T09:29:44Z [Term] id: GO:2000255 name: negative regulation of male germ cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of male germ cell proliferation." [GOC:obol] is_a: GO:1905937 ! negative regulation of germ cell proliferation is_a: GO:2000254 ! regulation of male germ cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002176 ! male germ cell proliferation relationship: negatively_regulates GO:0002176 ! male germ cell proliferation created_by: dph creation_date: 2010-11-18T09:29:47Z [Term] id: GO:2000256 name: positive regulation of male germ cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of male germ cell proliferation." [GOC:obol] is_a: GO:1905938 ! positive regulation of germ cell proliferation is_a: GO:2000254 ! regulation of male germ cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002176 ! male germ cell proliferation relationship: positively_regulates GO:0002176 ! male germ cell proliferation created_by: dph creation_date: 2010-11-18T09:29:50Z [Term] id: GO:2000269 name: regulation of fibroblast apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of fibroblast apoptotic process." [GOC:mtg_apoptosis, GOC:obol, GOC:yaf] synonym: "regulation of fibroblast apoptosis" NARROW [] is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0044346 ! fibroblast apoptotic process relationship: regulates GO:0044346 ! fibroblast apoptotic process created_by: jl creation_date: 2010-11-23T01:07:23Z [Term] id: GO:2000270 name: negative regulation of fibroblast apoptotic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast apoptotic process." [GOC:mtg_apoptosis, GOC:obol, GOC:yaf] synonym: "negative regulation of fibroblast apoptosis" NARROW [] is_a: GO:0043066 ! negative regulation of apoptotic process is_a: GO:2000269 ! regulation of fibroblast apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0044346 ! fibroblast apoptotic process relationship: negatively_regulates GO:0044346 ! fibroblast apoptotic process created_by: jl creation_date: 2010-11-23T01:07:27Z [Term] id: GO:2000271 name: positive regulation of fibroblast apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of fibroblast apoptotic process." [GOC:mtg_apoptosis, GOC:obol, GOC:yaf] synonym: "positive regulation of fibroblast apoptosis" NARROW [] is_a: GO:0043065 ! positive regulation of apoptotic process is_a: GO:2000269 ! regulation of fibroblast apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0044346 ! fibroblast apoptotic process relationship: positively_regulates GO:0044346 ! fibroblast apoptotic process created_by: jl creation_date: 2010-11-23T01:07:29Z [Term] id: GO:2000278 name: regulation of DNA biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of DNA biosynthetic process." [GOC:obol] synonym: "regulation of DNA anabolism" EXACT [GOC:obol] synonym: "regulation of DNA biosynthesis" EXACT [GOC:obol] synonym: "regulation of DNA formation" EXACT [GOC:obol] synonym: "regulation of DNA synthesis" EXACT [GOC:obol] is_a: GO:0010556 ! regulation of macromolecule biosynthetic process is_a: GO:0051052 ! regulation of DNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0071897 ! DNA biosynthetic process relationship: regulates GO:0071897 ! DNA biosynthetic process created_by: yaf creation_date: 2010-12-08T04:48:15Z [Term] id: GO:2000279 name: negative regulation of DNA biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of DNA biosynthetic process." [GOC:obol] synonym: "negative regulation of DNA anabolism" EXACT [GOC:obol] synonym: "negative regulation of DNA biosynthesis" EXACT [GOC:obol] synonym: "negative regulation of DNA formation" EXACT [GOC:obol] synonym: "negative regulation of DNA synthesis" EXACT [GOC:obol] is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process is_a: GO:0051053 ! negative regulation of DNA metabolic process is_a: GO:2000278 ! regulation of DNA biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0071897 ! DNA biosynthetic process relationship: negatively_regulates GO:0071897 ! DNA biosynthetic process created_by: yaf creation_date: 2010-12-08T04:48:20Z [Term] id: GO:2000282 name: regulation of cellular amino acid biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cellular amino acid biosynthetic process." [GOC:obol] synonym: "regulation of amino acid biosynthetic process" EXACT [GOC:obol] synonym: "regulation of cellular amino acid anabolism" EXACT [GOC:obol] synonym: "regulation of cellular amino acid biosynthesis" EXACT [GOC:obol] synonym: "regulation of cellular amino acid formation" EXACT [GOC:obol] synonym: "regulation of cellular amino acid synthesis" EXACT [GOC:obol] is_a: GO:0031326 ! regulation of cellular biosynthetic process is_a: GO:0051171 ! regulation of nitrogen compound metabolic process is_a: GO:0062012 ! regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0008652 ! amino acid biosynthetic process relationship: regulates GO:0008652 ! amino acid biosynthetic process created_by: vw creation_date: 2010-12-10T11:54:19Z [Term] id: GO:2000283 name: negative regulation of amino acid biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of an amino acid biosynthetic process." [GOC:obol] synonym: "negative regulation of amino acid anabolism" EXACT [GOC:obol] synonym: "negative regulation of amino acid biosynthesis" EXACT [GOC:obol] synonym: "negative regulation of amino acid formation" EXACT [GOC:obol] synonym: "negative regulation of amino acid synthesis" EXACT [GOC:obol] synonym: "negative regulation of cellular amino acid biosynthetic process" EXACT [GOC:obol] is_a: GO:0031327 ! negative regulation of cellular biosynthetic process is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process is_a: GO:0062014 ! negative regulation of small molecule metabolic process is_a: GO:2000282 ! regulation of cellular amino acid biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0008652 ! amino acid biosynthetic process relationship: negatively_regulates GO:0008652 ! amino acid biosynthetic process created_by: vw creation_date: 2010-12-10T11:54:23Z [Term] id: GO:2000284 name: positive regulation of amino acid biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cellular amino acid biosynthetic process." [GOC:obol] synonym: "positive regulation of amino acid anabolism" EXACT [GOC:obol] synonym: "positive regulation of amino acid biosynthesis" EXACT [GOC:obol] synonym: "positive regulation of amino acid formation" EXACT [GOC:obol] synonym: "positive regulation of amino acid synthesis" EXACT [GOC:obol] synonym: "positive regulation of cellular amino acid biosynthetic process" EXACT [GOC:obol] is_a: GO:0031328 ! positive regulation of cellular biosynthetic process is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process is_a: GO:0062013 ! positive regulation of small molecule metabolic process is_a: GO:2000282 ! regulation of cellular amino acid biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0008652 ! amino acid biosynthetic process relationship: positively_regulates GO:0008652 ! amino acid biosynthetic process created_by: vw creation_date: 2010-12-10T11:54:27Z [Term] id: GO:2000287 name: positive regulation of myotome development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of myotome development." [GOC:BHF] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:2000290 ! regulation of myotome development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0061055 ! myotome development relationship: positively_regulates GO:0061055 ! myotome development created_by: rl creation_date: 2010-12-16T05:17:15Z [Term] id: GO:2000288 name: positive regulation of myoblast proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of myoblast proliferation." [GOC:BHF] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:2000291 ! regulation of myoblast proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0051450 ! myoblast proliferation relationship: positively_regulates GO:0051450 ! myoblast proliferation created_by: rl creation_date: 2010-12-16T05:20:52Z [Term] id: GO:2000290 name: regulation of myotome development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of myotome development." [GOC:mah] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0061055 ! myotome development relationship: regulates GO:0061055 ! myotome development created_by: mah creation_date: 2010-12-20T10:22:05Z [Term] id: GO:2000291 name: regulation of myoblast proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of myoblast proliferation." [GOC:mah] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0051450 ! myoblast proliferation relationship: regulates GO:0051450 ! myoblast proliferation created_by: mah creation_date: 2010-12-20T10:34:26Z [Term] id: GO:2000292 name: regulation of defecation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of defecation." [GOC:obol] is_a: GO:0044058 ! regulation of digestive system process is_a: GO:0044062 ! regulation of excretion intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030421 ! defecation relationship: regulates GO:0030421 ! defecation created_by: bf creation_date: 2010-12-21T09:23:08Z [Term] id: GO:2000293 name: negative regulation of defecation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of defecation." [GOC:obol] is_a: GO:0051048 ! negative regulation of secretion is_a: GO:0060457 ! negative regulation of digestive system process is_a: GO:2000292 ! regulation of defecation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030421 ! defecation relationship: negatively_regulates GO:0030421 ! defecation created_by: bf creation_date: 2010-12-21T09:23:13Z [Term] id: GO:2000294 name: positive regulation of defecation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of defecation." [GOC:obol] is_a: GO:0051047 ! positive regulation of secretion is_a: GO:0060456 ! positive regulation of digestive system process is_a: GO:2000292 ! regulation of defecation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030421 ! defecation relationship: positively_regulates GO:0030421 ! defecation created_by: bf creation_date: 2010-12-21T09:23:16Z [Term] id: GO:2000351 name: regulation of endothelial cell apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of endothelial cell apoptotic process." [GOC:mah, GOC:mtg_apoptosis] synonym: "regulation of apoptosis of endothelial cells" EXACT [GOC:obol] synonym: "regulation of endothelial cell apoptosis" NARROW [] synonym: "regulation of endothelial cell programmed cell death by apoptosis" EXACT [GOC:obol] synonym: "regulation of killing of endothelial cells" EXACT [GOC:obol] synonym: "regulation of programmed cell death of endothelial cells by apoptosis" EXACT [GOC:obol] synonym: "regulation of programmed cell death, endothelial cells" EXACT [GOC:obol] is_a: GO:1904035 ! regulation of epithelial cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0072577 ! endothelial cell apoptotic process relationship: regulates GO:0072577 ! endothelial cell apoptotic process created_by: mah creation_date: 2011-02-03T10:43:16Z [Term] id: GO:2000352 name: negative regulation of endothelial cell apoptotic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell apoptotic process." [GOC:BHF, GOC:mah, GOC:mtg_apoptosis] synonym: "negative regulation of apoptosis of endothelial cells" EXACT [GOC:obol] synonym: "negative regulation of endothelial cell apoptosis" NARROW [] synonym: "negative regulation of endothelial cell programmed cell death by apoptosis" EXACT [GOC:obol] synonym: "negative regulation of killing of endothelial cells" EXACT [GOC:obol] synonym: "negative regulation of programmed cell death of endothelial cells by apoptosis" EXACT [GOC:obol] synonym: "negative regulation of programmed cell death, endothelial cells" EXACT [GOC:obol] is_a: GO:1904036 ! negative regulation of epithelial cell apoptotic process is_a: GO:2000351 ! regulation of endothelial cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0072577 ! endothelial cell apoptotic process relationship: negatively_regulates GO:0072577 ! endothelial cell apoptotic process created_by: mah creation_date: 2011-02-03T10:43:20Z [Term] id: GO:2000353 name: positive regulation of endothelial cell apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of endothelial cell apoptotic process." [GOC:BHF, GOC:mah, GOC:mtg_apoptosis] synonym: "positive regulation of apoptosis of endothelial cells" EXACT [GOC:obol] synonym: "positive regulation of endothelial cell apoptosis" NARROW [] synonym: "positive regulation of endothelial cell programmed cell death by apoptosis" EXACT [GOC:obol] synonym: "positive regulation of killing of endothelial cells" EXACT [GOC:obol] synonym: "positive regulation of programmed cell death of endothelial cells by apoptosis" EXACT [GOC:obol] synonym: "positive regulation of programmed cell death, endothelial cells" EXACT [GOC:obol] is_a: GO:1904037 ! positive regulation of epithelial cell apoptotic process is_a: GO:2000351 ! regulation of endothelial cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0072577 ! endothelial cell apoptotic process relationship: positively_regulates GO:0072577 ! endothelial cell apoptotic process created_by: mah creation_date: 2011-02-03T10:43:23Z [Term] id: GO:2000374 name: regulation of oxygen metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of oxygen metabolic process." [GOC:mah] synonym: "regulation of diatomic oxygen metabolic process" EXACT [GOC:obol] synonym: "regulation of oxygen metabolism" EXACT [GOC:obol] is_a: GO:0031323 ! regulation of cellular metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0072592 ! oxygen metabolic process relationship: regulates GO:0072592 ! oxygen metabolic process created_by: mah creation_date: 2011-02-11T02:03:32Z [Term] id: GO:2000375 name: negative regulation of oxygen metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of oxygen metabolic process." [GOC:mah] synonym: "negative regulation of diatomic oxygen metabolic process" EXACT [GOC:obol] synonym: "negative regulation of oxygen metabolism" EXACT [GOC:obol] is_a: GO:0031324 ! negative regulation of cellular metabolic process is_a: GO:2000374 ! regulation of oxygen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0072592 ! oxygen metabolic process relationship: negatively_regulates GO:0072592 ! oxygen metabolic process created_by: mah creation_date: 2011-02-11T02:03:44Z [Term] id: GO:2000376 name: positive regulation of oxygen metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of oxygen metabolic process." [GOC:mah] synonym: "positive regulation of diatomic oxygen metabolic process" EXACT [GOC:obol] synonym: "positive regulation of oxygen metabolism" EXACT [GOC:obol] is_a: GO:0031325 ! positive regulation of cellular metabolic process is_a: GO:2000374 ! regulation of oxygen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0072592 ! oxygen metabolic process relationship: positively_regulates GO:0072592 ! oxygen metabolic process created_by: mah creation_date: 2011-02-11T02:03:52Z [Term] id: GO:2000380 name: regulation of mesoderm development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mesoderm development." [GOC:BHF] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007498 ! mesoderm development relationship: regulates GO:0007498 ! mesoderm development created_by: vk creation_date: 2011-02-15T03:09:46Z [Term] id: GO:2000381 name: negative regulation of mesoderm development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm development." [GOC:BHF] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:2000380 ! regulation of mesoderm development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007498 ! mesoderm development relationship: negatively_regulates GO:0007498 ! mesoderm development created_by: vk creation_date: 2011-02-15T03:10:02Z [Term] id: GO:2000382 name: positive regulation of mesoderm development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mesoderm development." [GOC:BHF] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:2000380 ! regulation of mesoderm development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007498 ! mesoderm development relationship: positively_regulates GO:0007498 ! mesoderm development created_by: vk creation_date: 2011-02-15T03:10:12Z [Term] id: GO:2000383 name: regulation of ectoderm development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of ectoderm development." [GOC:BHF] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007398 ! ectoderm development relationship: regulates GO:0007398 ! ectoderm development created_by: vk creation_date: 2011-02-15T03:17:10Z [Term] id: GO:2000384 name: negative regulation of ectoderm development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of ectoderm development." [GOC:BHF] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:2000383 ! regulation of ectoderm development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007398 ! ectoderm development relationship: negatively_regulates GO:0007398 ! ectoderm development created_by: vk creation_date: 2011-02-15T03:17:27Z [Term] id: GO:2000385 name: positive regulation of ectoderm development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of ectoderm development." [GOC:BHF] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:2000383 ! regulation of ectoderm development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007398 ! ectoderm development relationship: positively_regulates GO:0007398 ! ectoderm development created_by: vk creation_date: 2011-02-15T03:17:39Z [Term] id: GO:2000401 name: regulation of lymphocyte migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of lymphocyte migration." [GOC:mah] is_a: GO:0071675 ! regulation of mononuclear cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0072676 ! lymphocyte migration relationship: regulates GO:0072676 ! lymphocyte migration created_by: mah creation_date: 2011-02-23T10:45:19Z [Term] id: GO:2000402 name: negative regulation of lymphocyte migration namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte migration." [GOC:mah] is_a: GO:0071676 ! negative regulation of mononuclear cell migration is_a: GO:2000401 ! regulation of lymphocyte migration intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0072676 ! lymphocyte migration relationship: negatively_regulates GO:0072676 ! lymphocyte migration created_by: mah creation_date: 2011-02-23T10:45:47Z [Term] id: GO:2000403 name: positive regulation of lymphocyte migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of lymphocyte migration." [GOC:mah] is_a: GO:0071677 ! positive regulation of mononuclear cell migration is_a: GO:2000401 ! regulation of lymphocyte migration intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0072676 ! lymphocyte migration relationship: positively_regulates GO:0072676 ! lymphocyte migration created_by: mah creation_date: 2011-02-23T10:46:06Z [Term] id: GO:2000404 name: regulation of T cell migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of T cell migration." [GOC:mah] synonym: "regulation of T lymphocyte migration" EXACT [GOC:obol] synonym: "regulation of T-cell migration" EXACT [GOC:obol] synonym: "regulation of T-lymphocyte migration" EXACT [GOC:obol] is_a: GO:2000401 ! regulation of lymphocyte migration intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0072678 ! T cell migration relationship: regulates GO:0072678 ! T cell migration created_by: mah creation_date: 2011-02-23T10:48:24Z [Term] id: GO:2000405 name: negative regulation of T cell migration namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of T cell migration." [GOC:mah] synonym: "negative regulation of T lymphocyte migration" EXACT [GOC:obol] synonym: "negative regulation of T-cell migration" EXACT [GOC:obol] synonym: "negative regulation of T-lymphocyte migration" EXACT [GOC:obol] is_a: GO:2000402 ! negative regulation of lymphocyte migration is_a: GO:2000404 ! regulation of T cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0072678 ! T cell migration relationship: negatively_regulates GO:0072678 ! T cell migration created_by: mah creation_date: 2011-02-23T10:48:52Z [Term] id: GO:2000406 name: positive regulation of T cell migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of T cell migration." [GOC:mah] synonym: "positive regulation of T lymphocyte migration" EXACT [GOC:obol] synonym: "positive regulation of T-cell migration" EXACT [GOC:obol] synonym: "positive regulation of T-lymphocyte migration" EXACT [GOC:obol] is_a: GO:2000403 ! positive regulation of lymphocyte migration is_a: GO:2000404 ! regulation of T cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0072678 ! T cell migration relationship: positively_regulates GO:0072678 ! T cell migration created_by: mah creation_date: 2011-02-23T10:49:12Z [Term] id: GO:2000471 name: regulation of hematopoietic stem cell migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of hematopoietic stem cell migration." [GOC:obol] synonym: "regulation of hemopoietic stem cell migration" EXACT [GOC:obol] is_a: GO:0030334 ! regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0035701 ! hematopoietic stem cell migration relationship: regulates GO:0035701 ! hematopoietic stem cell migration created_by: bf creation_date: 2011-03-09T09:34:08Z [Term] id: GO:2000472 name: negative regulation of hematopoietic stem cell migration namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell migration." [GOC:obol] synonym: "negative regulation of hemopoietic stem cell migration" EXACT [GOC:obol] is_a: GO:0030336 ! negative regulation of cell migration is_a: GO:2000471 ! regulation of hematopoietic stem cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0035701 ! hematopoietic stem cell migration relationship: negatively_regulates GO:0035701 ! hematopoietic stem cell migration created_by: bf creation_date: 2011-03-09T09:34:54Z [Term] id: GO:2000473 name: positive regulation of hematopoietic stem cell migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell migration." [GOC:obol] synonym: "positive regulation of hemopoietic stem cell migration" EXACT [GOC:obol] is_a: GO:0030335 ! positive regulation of cell migration is_a: GO:2000471 ! regulation of hematopoietic stem cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0035701 ! hematopoietic stem cell migration relationship: positively_regulates GO:0035701 ! hematopoietic stem cell migration created_by: bf creation_date: 2011-03-09T09:35:25Z [Term] id: GO:2000495 name: regulation of cell proliferation involved in compound eye morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis." [GOC:obol] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0035736 ! cell proliferation involved in compound eye morphogenesis relationship: regulates GO:0035736 ! cell proliferation involved in compound eye morphogenesis created_by: bf creation_date: 2011-03-18T02:18:34Z [Term] id: GO:2000496 name: negative regulation of cell proliferation involved in compound eye morphogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis." [GOC:obol] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:2000495 ! regulation of cell proliferation involved in compound eye morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0035736 ! cell proliferation involved in compound eye morphogenesis relationship: negatively_regulates GO:0035736 ! cell proliferation involved in compound eye morphogenesis created_by: bf creation_date: 2011-03-18T02:19:22Z [Term] id: GO:2000497 name: positive regulation of cell proliferation involved in compound eye morphogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis." [GOC:obol] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:2000495 ! regulation of cell proliferation involved in compound eye morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0035736 ! cell proliferation involved in compound eye morphogenesis relationship: positively_regulates GO:0035736 ! cell proliferation involved in compound eye morphogenesis created_by: bf creation_date: 2011-03-18T02:19:54Z [Term] id: GO:2000542 name: negative regulation of gastrulation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of gastrulation." [GOC:obol] is_a: GO:0010470 ! regulation of gastrulation is_a: GO:0045992 ! negative regulation of embryonic development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007369 ! gastrulation relationship: negatively_regulates GO:0007369 ! gastrulation created_by: yaf creation_date: 2011-04-01T04:10:08Z [Term] id: GO:2000543 name: positive regulation of gastrulation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of gastrulation." [GOC:obol] is_a: GO:0010470 ! regulation of gastrulation is_a: GO:0040019 ! positive regulation of embryonic development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007369 ! gastrulation relationship: positively_regulates GO:0007369 ! gastrulation created_by: yaf creation_date: 2011-04-01T04:10:15Z [Term] id: GO:2000547 name: regulation of dendritic cell dendrite assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of dendritic cell dendrite assembly." [GOC:obol] synonym: "regulation of dendritic extension" RELATED [GOC:obol] is_a: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0097026 ! dendritic cell dendrite assembly relationship: regulates GO:0097026 ! dendritic cell dendrite assembly created_by: ebc creation_date: 2011-04-03T07:21:55Z [Term] id: GO:2000548 name: negative regulation of dendritic cell dendrite assembly namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell dendrite assembly." [GOC:obol] synonym: "negative regulation of dendritic extension" RELATED [GOC:obol] is_a: GO:0120033 ! negative regulation of plasma membrane bounded cell projection assembly is_a: GO:2000547 ! regulation of dendritic cell dendrite assembly intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0097026 ! dendritic cell dendrite assembly relationship: negatively_regulates GO:0097026 ! dendritic cell dendrite assembly created_by: ebc creation_date: 2011-04-03T07:22:01Z [Term] id: GO:2000549 name: positive regulation of dendritic cell dendrite assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of dendritic cell dendrite assembly." [GOC:obol] synonym: "positive regulation of dendritic extension" RELATED [GOC:obol] is_a: GO:0120034 ! positive regulation of plasma membrane bounded cell projection assembly is_a: GO:2000547 ! regulation of dendritic cell dendrite assembly intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0097026 ! dendritic cell dendrite assembly relationship: positively_regulates GO:0097026 ! dendritic cell dendrite assembly created_by: ebc creation_date: 2011-04-03T07:22:06Z [Term] id: GO:2000573 name: positive regulation of DNA biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of DNA biosynthetic process." [GOC:obol] synonym: "positive regulation of DNA anabolism" EXACT [GOC:obol] synonym: "positive regulation of DNA biosynthesis" EXACT [GOC:obol] synonym: "positive regulation of DNA formation" EXACT [GOC:obol] synonym: "positive regulation of DNA synthesis" EXACT [GOC:obol] is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process is_a: GO:0051054 ! positive regulation of DNA metabolic process is_a: GO:2000278 ! regulation of DNA biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0071897 ! DNA biosynthetic process relationship: positively_regulates GO:0071897 ! DNA biosynthetic process created_by: yaf creation_date: 2011-04-04T10:01:20Z [Term] id: GO:2000606 name: regulation of cell proliferation involved in mesonephros development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell proliferation involved in mesonephros development." [GOC:obol] is_a: GO:1901722 ! regulation of cell proliferation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0061209 ! cell proliferation involved in mesonephros development relationship: regulates GO:0061209 ! cell proliferation involved in mesonephros development created_by: yaf creation_date: 2011-04-18T08:42:19Z [Term] id: GO:2000607 name: negative regulation of cell proliferation involved in mesonephros development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in mesonephros development." [GOC:obol] is_a: GO:1901723 ! negative regulation of cell proliferation involved in kidney development is_a: GO:2000606 ! regulation of cell proliferation involved in mesonephros development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0061209 ! cell proliferation involved in mesonephros development relationship: negatively_regulates GO:0061209 ! cell proliferation involved in mesonephros development created_by: yaf creation_date: 2011-04-18T08:42:23Z [Term] id: GO:2000608 name: positive regulation of cell proliferation involved in mesonephros development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell proliferation involved in mesonephros development." [GOC:obol] is_a: GO:1901724 ! positive regulation of cell proliferation involved in kidney development is_a: GO:2000606 ! regulation of cell proliferation involved in mesonephros development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0061209 ! cell proliferation involved in mesonephros development relationship: positively_regulates GO:0061209 ! cell proliferation involved in mesonephros development created_by: yaf creation_date: 2011-04-18T08:42:25Z [Term] id: GO:2000647 name: negative regulation of stem cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of stem cell proliferation." [GOC:dph] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0072091 ! regulation of stem cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0072089 ! stem cell proliferation relationship: negatively_regulates GO:0072089 ! stem cell proliferation created_by: dph creation_date: 2011-04-27T01:04:22Z [Term] id: GO:2000648 name: positive regulation of stem cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of stem cell proliferation." [GOC:dph] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0072091 ! regulation of stem cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0072089 ! stem cell proliferation relationship: positively_regulates GO:0072089 ! stem cell proliferation created_by: dph creation_date: 2011-04-27T01:04:25Z [Term] id: GO:2000649 name: regulation of sodium ion transmembrane transporter activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of sodium ion transmembrane transporter activity." [GOC:obol] subset: gocheck_do_not_annotate synonym: "regulation of sodium transporter activity" EXACT [GOC:obol] is_a: GO:0032412 ! regulation of monoatomic ion transmembrane transporter activity is_a: GO:1902305 ! regulation of sodium ion transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0015081 ! sodium ion transmembrane transporter activity relationship: regulates GO:0015081 ! sodium ion transmembrane transporter activity created_by: yaf creation_date: 2011-04-28T08:42:53Z [Term] id: GO:2000650 name: negative regulation of sodium ion transmembrane transporter activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transporter activity." [GOC:obol] subset: gocheck_do_not_annotate synonym: "negative regulation of sodium transporter activity" EXACT [GOC:obol] is_a: GO:0032413 ! negative regulation of ion transmembrane transporter activity is_a: GO:1902306 ! negative regulation of sodium ion transmembrane transport is_a: GO:2000649 ! regulation of sodium ion transmembrane transporter activity intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0015081 ! sodium ion transmembrane transporter activity relationship: negatively_regulates GO:0015081 ! sodium ion transmembrane transporter activity created_by: yaf creation_date: 2011-04-28T08:42:57Z [Term] id: GO:2000651 name: positive regulation of sodium ion transmembrane transporter activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transporter activity." [GOC:obol] subset: gocheck_do_not_annotate synonym: "positive regulation of sodium transporter activity" EXACT [GOC:obol] is_a: GO:0032414 ! positive regulation of ion transmembrane transporter activity is_a: GO:1902307 ! positive regulation of sodium ion transmembrane transport is_a: GO:2000649 ! regulation of sodium ion transmembrane transporter activity intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0015081 ! sodium ion transmembrane transporter activity relationship: positively_regulates GO:0015081 ! sodium ion transmembrane transporter activity created_by: yaf creation_date: 2011-04-28T08:43:00Z [Term] id: GO:2000668 name: regulation of dendritic cell apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of dendritic cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] synonym: "regulation of dendritic cell apoptosis" NARROW [] is_a: GO:2000106 ! regulation of leukocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0097048 ! dendritic cell apoptotic process relationship: regulates GO:0097048 ! dendritic cell apoptotic process created_by: pr creation_date: 2011-05-09T07:34:16Z [Term] id: GO:2000669 name: negative regulation of dendritic cell apoptotic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] synonym: "negative regulation of dendritic cell apoptosis" NARROW [] is_a: GO:2000107 ! negative regulation of leukocyte apoptotic process is_a: GO:2000668 ! regulation of dendritic cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0097048 ! dendritic cell apoptotic process relationship: negatively_regulates GO:0097048 ! dendritic cell apoptotic process created_by: pr creation_date: 2011-05-09T07:34:21Z [Term] id: GO:2000670 name: positive regulation of dendritic cell apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of dendritic cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] synonym: "positive regulation of dendritic cell apoptosis" NARROW [] is_a: GO:2000108 ! positive regulation of leukocyte apoptotic process is_a: GO:2000668 ! regulation of dendritic cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0097048 ! dendritic cell apoptotic process relationship: positively_regulates GO:0097048 ! dendritic cell apoptotic process created_by: pr creation_date: 2011-05-09T07:34:26Z [Term] id: GO:2000671 name: regulation of motor neuron apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of motor neuron apoptotic process." [GOC:mtg_apoptosis, GOC:obol] synonym: "regulation of motoneuron apoptosis" EXACT [GOC:obol] synonym: "regulation of motor neuron apoptosis" NARROW [] is_a: GO:0043523 ! regulation of neuron apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0097049 ! motor neuron apoptotic process relationship: regulates GO:0097049 ! motor neuron apoptotic process created_by: pr creation_date: 2011-05-09T10:56:17Z [Term] id: GO:2000672 name: negative regulation of motor neuron apoptotic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron apoptotic process." [GOC:mtg_apoptosis, GOC:obol] synonym: "negative regulation of motoneuron apoptosis" EXACT [GOC:obol] synonym: "negative regulation of motor neuron apoptosis" NARROW [] is_a: GO:0043524 ! negative regulation of neuron apoptotic process is_a: GO:2000671 ! regulation of motor neuron apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0097049 ! motor neuron apoptotic process relationship: negatively_regulates GO:0097049 ! motor neuron apoptotic process created_by: pr creation_date: 2011-05-09T10:56:21Z [Term] id: GO:2000673 name: positive regulation of motor neuron apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of motor neuron apoptotic process." [GOC:mtg_apoptosis, GOC:obol] synonym: "positive regulation of motoneuron apoptosis" EXACT [GOC:obol] synonym: "positive regulation of motor neuron apoptosis" NARROW [] is_a: GO:0043525 ! positive regulation of neuron apoptotic process is_a: GO:2000671 ! regulation of motor neuron apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0097049 ! motor neuron apoptotic process relationship: positively_regulates GO:0097049 ! motor neuron apoptotic process created_by: pr creation_date: 2011-05-09T10:56:24Z [Term] id: GO:2000674 name: regulation of type B pancreatic cell apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of type B pancreatic cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] synonym: "regulation of pancreatic B cell apoptosis" EXACT [GOC:obol] synonym: "regulation of pancreatic beta cell apoptosis" EXACT [GOC:obol] synonym: "regulation of type B pancreatic cell apoptosis" NARROW [] is_a: GO:1904035 ! regulation of epithelial cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0097050 ! type B pancreatic cell apoptotic process relationship: regulates GO:0097050 ! type B pancreatic cell apoptotic process created_by: pr creation_date: 2011-05-09T11:51:09Z [Term] id: GO:2000675 name: negative regulation of type B pancreatic cell apoptotic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] synonym: "negative regulation of pancreatic B cell apoptosis" EXACT [GOC:obol] synonym: "negative regulation of pancreatic beta cell apoptosis" EXACT [GOC:obol] synonym: "negative regulation of type B pancreatic cell apoptosis" NARROW [] is_a: GO:1904036 ! negative regulation of epithelial cell apoptotic process is_a: GO:2000674 ! regulation of type B pancreatic cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0097050 ! type B pancreatic cell apoptotic process relationship: negatively_regulates GO:0097050 ! type B pancreatic cell apoptotic process created_by: pr creation_date: 2011-05-09T11:51:12Z [Term] id: GO:2000676 name: positive regulation of type B pancreatic cell apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of type B pancreatic cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] synonym: "positive regulation of pancreatic B cell apoptosis" EXACT [GOC:obol] synonym: "positive regulation of pancreatic beta cell apoptosis" EXACT [GOC:obol] synonym: "positive regulation of type B pancreatic cell apoptosis" NARROW [] is_a: GO:1904037 ! positive regulation of epithelial cell apoptotic process is_a: GO:2000674 ! regulation of type B pancreatic cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0097050 ! type B pancreatic cell apoptotic process relationship: positively_regulates GO:0097050 ! type B pancreatic cell apoptotic process created_by: pr creation_date: 2011-05-09T11:51:15Z [Term] id: GO:2000690 name: regulation of cardiac muscle cell myoblast differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac muscle cell myoblast differentiation." [GOC:obol] synonym: "regulation of cardiac myoblast differentiation" RELATED [GOC:obol] synonym: "regulation of myocardial precursor cell differentiation" EXACT [GOC:obol] is_a: GO:0045661 ! regulation of myoblast differentiation is_a: GO:0051890 ! regulation of cardioblast differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060379 ! cardiac muscle cell myoblast differentiation relationship: regulates GO:0060379 ! cardiac muscle cell myoblast differentiation created_by: yaf creation_date: 2011-05-25T09:08:01Z [Term] id: GO:2000691 name: negative regulation of cardiac muscle cell myoblast differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell myoblast differentiation." [GOC:obol] synonym: "negative regulation of cardiac myoblast differentiation" RELATED [GOC:obol] synonym: "negative regulation of myocardial precursor cell differentiation" EXACT [GOC:obol] is_a: GO:0045662 ! negative regulation of myoblast differentiation is_a: GO:0051892 ! negative regulation of cardioblast differentiation is_a: GO:2000690 ! regulation of cardiac muscle cell myoblast differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060379 ! cardiac muscle cell myoblast differentiation relationship: negatively_regulates GO:0060379 ! cardiac muscle cell myoblast differentiation created_by: yaf creation_date: 2011-05-25T09:08:06Z [Term] id: GO:2000696 name: regulation of epithelial cell differentiation involved in kidney development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of epithelial cell differentiation involved in kidney development." [GOC:mtg_kidney_jan10, GOC:yaf] is_a: GO:0030856 ! regulation of epithelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0035850 ! epithelial cell differentiation involved in kidney development relationship: regulates GO:0035850 ! epithelial cell differentiation involved in kidney development created_by: bf creation_date: 2011-05-16T04:23:52Z [Term] id: GO:2000697 name: negative regulation of epithelial cell differentiation involved in kidney development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell differentiation involved in kidney development." [GOC:mtg_kidney_jan10, GOC:yaf] is_a: GO:0030857 ! negative regulation of epithelial cell differentiation is_a: GO:2000696 ! regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0035850 ! epithelial cell differentiation involved in kidney development relationship: negatively_regulates GO:0035850 ! epithelial cell differentiation involved in kidney development created_by: bf creation_date: 2011-05-16T04:23:55Z [Term] id: GO:2000698 name: positive regulation of epithelial cell differentiation involved in kidney development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation involved in kidney development." [GOC:mtg_kidney_jan10, GOC:yaf] is_a: GO:0030858 ! positive regulation of epithelial cell differentiation is_a: GO:2000696 ! regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0035850 ! epithelial cell differentiation involved in kidney development relationship: positively_regulates GO:0035850 ! epithelial cell differentiation involved in kidney development created_by: bf creation_date: 2011-05-16T04:23:57Z [Term] id: GO:2000700 name: positive regulation of cardiac muscle cell myoblast differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cardiac muscle cell myoblast differentiation." [GOC:obol] synonym: "positive regulation of cardiac myoblast differentiation" RELATED [GOC:obol] synonym: "positive regulation of myocardial precursor cell differentiation" EXACT [GOC:obol] is_a: GO:0045663 ! positive regulation of myoblast differentiation is_a: GO:0051891 ! positive regulation of cardioblast differentiation is_a: GO:2000690 ! regulation of cardiac muscle cell myoblast differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060379 ! cardiac muscle cell myoblast differentiation relationship: positively_regulates GO:0060379 ! cardiac muscle cell myoblast differentiation created_by: yaf creation_date: 2011-05-25T09:08:09Z [Term] id: GO:2000725 name: regulation of cardiac muscle cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac muscle cell differentiation." [GOC:BHF] synonym: "regulation of cardiomyocyte differentiation" EXACT [GOC:obol] synonym: "regulation of heart muscle cell differentiation" RELATED [GOC:obol] is_a: GO:0051153 ! regulation of striated muscle cell differentiation is_a: GO:1905207 ! regulation of cardiocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0055007 ! cardiac muscle cell differentiation relationship: regulates GO:0055007 ! cardiac muscle cell differentiation created_by: vk creation_date: 2011-06-08T10:51:06Z [Term] id: GO:2000726 name: negative regulation of cardiac muscle cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell differentiation." [GOC:BHF] synonym: "negative regulation of cardiomyocyte differentiation" EXACT [GOC:obol] synonym: "negative regulation of heart muscle cell differentiation" RELATED [GOC:obol] is_a: GO:0051154 ! negative regulation of striated muscle cell differentiation is_a: GO:1905208 ! negative regulation of cardiocyte differentiation is_a: GO:2000725 ! regulation of cardiac muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0055007 ! cardiac muscle cell differentiation relationship: negatively_regulates GO:0055007 ! cardiac muscle cell differentiation created_by: vk creation_date: 2011-06-08T10:51:11Z [Term] id: GO:2000727 name: positive regulation of cardiac muscle cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cardiac muscle cell differentiation." [GOC:BHF] synonym: "positive regulation of cardiomyocyte differentiation" EXACT [GOC:obol] synonym: "positive regulation of heart muscle cell differentiation" RELATED [GOC:obol] is_a: GO:0051155 ! positive regulation of striated muscle cell differentiation is_a: GO:1905209 ! positive regulation of cardiocyte differentiation is_a: GO:2000725 ! regulation of cardiac muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0055007 ! cardiac muscle cell differentiation relationship: positively_regulates GO:0055007 ! cardiac muscle cell differentiation created_by: vk creation_date: 2011-06-08T10:51:15Z [Term] id: GO:2000729 name: positive regulation of mesenchymal cell proliferation involved in ureter development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in ureter development." [GOC:obol] synonym: "positive regulation of ureter mesenchymal cell proliferation" RELATED [GOC:obol] synonym: "positive regulation of ureteral mesenchymal cell proliferation" RELATED [GOC:obol] is_a: GO:0002053 ! positive regulation of mesenchymal cell proliferation is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0072199 ! regulation of mesenchymal cell proliferation involved in ureter development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0072198 ! mesenchymal cell proliferation involved in ureter development relationship: positively_regulates GO:0072198 ! mesenchymal cell proliferation involved in ureter development created_by: yaf creation_date: 2011-06-10T02:27:19Z [Term] id: GO:2000736 name: regulation of stem cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of stem cell differentiation." [GOC:obol] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048863 ! stem cell differentiation relationship: regulates GO:0048863 ! stem cell differentiation created_by: yaf creation_date: 2011-06-14T02:05:16Z [Term] id: GO:2000737 name: negative regulation of stem cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation." [GOC:obol] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:2000736 ! regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048863 ! stem cell differentiation relationship: negatively_regulates GO:0048863 ! stem cell differentiation created_by: yaf creation_date: 2011-06-14T02:05:20Z [Term] id: GO:2000738 name: positive regulation of stem cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of stem cell differentiation." [GOC:obol] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:2000736 ! regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048863 ! stem cell differentiation relationship: positively_regulates GO:0048863 ! stem cell differentiation created_by: yaf creation_date: 2011-06-14T02:05:23Z [Term] id: GO:2000768 name: positive regulation of nephron tubule epithelial cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of nephron tubule epithelial cell differentiation." [GOC:obol] is_a: GO:0072182 ! regulation of nephron tubule epithelial cell differentiation is_a: GO:2000698 ! positive regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0072160 ! nephron tubule epithelial cell differentiation relationship: positively_regulates GO:0072160 ! nephron tubule epithelial cell differentiation created_by: yaf creation_date: 2011-06-22T11:55:06Z [Term] id: GO:2000790 name: regulation of mesenchymal cell proliferation involved in lung development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation involved in lung development." [PMID:21513708] is_a: GO:0010464 ! regulation of mesenchymal cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060916 ! mesenchymal cell proliferation involved in lung development relationship: regulates GO:0060916 ! mesenchymal cell proliferation involved in lung development created_by: pr creation_date: 2011-06-24T01:53:50Z [Term] id: GO:2000791 name: negative regulation of mesenchymal cell proliferation involved in lung development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell proliferation involved in lung development." [PMID:21513708] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:0072201 ! negative regulation of mesenchymal cell proliferation is_a: GO:2000790 ! regulation of mesenchymal cell proliferation involved in lung development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060916 ! mesenchymal cell proliferation involved in lung development relationship: negatively_regulates GO:0060916 ! mesenchymal cell proliferation involved in lung development created_by: pr creation_date: 2011-06-24T01:53:53Z [Term] id: GO:2000792 name: positive regulation of mesenchymal cell proliferation involved in lung development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in lung development." [PMID:21513708] is_a: GO:0002053 ! positive regulation of mesenchymal cell proliferation is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:2000790 ! regulation of mesenchymal cell proliferation involved in lung development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060916 ! mesenchymal cell proliferation involved in lung development relationship: positively_regulates GO:0060916 ! mesenchymal cell proliferation involved in lung development created_by: pr creation_date: 2011-06-24T01:53:56Z [Term] id: GO:2000794 name: regulation of epithelial cell proliferation involved in lung morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis." [PMID:21513708] is_a: GO:0050678 ! regulation of epithelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060502 ! epithelial cell proliferation involved in lung morphogenesis relationship: regulates GO:0060502 ! epithelial cell proliferation involved in lung morphogenesis created_by: pr creation_date: 2011-06-25T07:22:38Z [Term] id: GO:2000795 name: negative regulation of epithelial cell proliferation involved in lung morphogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis." [PMID:21513708] is_a: GO:0050680 ! negative regulation of epithelial cell proliferation is_a: GO:2000794 ! regulation of epithelial cell proliferation involved in lung morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060502 ! epithelial cell proliferation involved in lung morphogenesis relationship: negatively_regulates GO:0060502 ! epithelial cell proliferation involved in lung morphogenesis created_by: pr creation_date: 2011-06-25T07:22:42Z [Term] id: GO:2000818 name: negative regulation of myoblast proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of myoblast proliferation." [GOC:obol] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:2000291 ! regulation of myoblast proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0051450 ! myoblast proliferation relationship: negatively_regulates GO:0051450 ! myoblast proliferation created_by: pr creation_date: 2011-07-12T03:06:04Z [Term] id: GO:2000826 name: regulation of heart morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of heart morphogenesis." [GOC:BHF] synonym: "regulation of cardiac morphogenesis" RELATED [GOC:obol] is_a: GO:2000027 ! regulation of animal organ morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003007 ! heart morphogenesis relationship: regulates GO:0003007 ! heart morphogenesis created_by: vk creation_date: 2011-07-19T10:08:58Z [Term] id: GO:2000831 name: regulation of steroid hormone secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of steroid hormone secretion." [GOC:sl] is_a: GO:0032368 ! regulation of lipid transport is_a: GO:0044060 ! regulation of endocrine process is_a: GO:0046883 ! regulation of hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0035929 ! steroid hormone secretion relationship: regulates GO:0035929 ! steroid hormone secretion created_by: bf creation_date: 2011-07-26T08:38:46Z [Term] id: GO:2000832 name: negative regulation of steroid hormone secretion namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of steroid hormone secretion." [GOC:sl] is_a: GO:0032369 ! negative regulation of lipid transport is_a: GO:0046888 ! negative regulation of hormone secretion is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:2000831 ! regulation of steroid hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0035929 ! steroid hormone secretion relationship: negatively_regulates GO:0035929 ! steroid hormone secretion created_by: bf creation_date: 2011-07-26T08:38:50Z [Term] id: GO:2000833 name: positive regulation of steroid hormone secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of steroid hormone secretion." [GOC:sl] is_a: GO:0032370 ! positive regulation of lipid transport is_a: GO:0046887 ! positive regulation of hormone secretion is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:2000831 ! regulation of steroid hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0035929 ! steroid hormone secretion relationship: positively_regulates GO:0035929 ! steroid hormone secretion created_by: bf creation_date: 2011-07-26T08:38:51Z [Term] id: GO:2000834 name: regulation of androgen secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of androgen secretion." [GOC:sl] is_a: GO:2000831 ! regulation of steroid hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0035935 ! androgen secretion relationship: regulates GO:0035935 ! androgen secretion created_by: bf creation_date: 2011-07-26T08:39:45Z [Term] id: GO:2000835 name: negative regulation of androgen secretion namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of androgen secretion." [GOC:sl] is_a: GO:2000832 ! negative regulation of steroid hormone secretion is_a: GO:2000834 ! regulation of androgen secretion intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0035935 ! androgen secretion relationship: negatively_regulates GO:0035935 ! androgen secretion created_by: bf creation_date: 2011-07-26T08:39:48Z [Term] id: GO:2000836 name: positive regulation of androgen secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of androgen secretion." [GOC:sl] is_a: GO:2000833 ! positive regulation of steroid hormone secretion is_a: GO:2000834 ! regulation of androgen secretion intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0035935 ! androgen secretion relationship: positively_regulates GO:0035935 ! androgen secretion created_by: bf creation_date: 2011-07-26T08:39:51Z [Term] id: GO:2001012 name: mesenchymal cell differentiation involved in renal system development namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the renal system as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10, GOC:obol, GOC:yaf] synonym: "mesenchymal cell differentiation involved in urinary system development" RELATED [GOC:obol] synonym: "mesenchymal cell differentiation involved in urinary tract development" RELATED [GOC:obol] is_a: GO:0048762 ! mesenchymal cell differentiation intersection_of: GO:0048762 ! mesenchymal cell differentiation intersection_of: part_of GO:0072001 ! renal system development relationship: part_of GO:0072001 ! renal system development created_by: yaf creation_date: 2011-08-09T04:05:14Z [Term] id: GO:2001013 name: epithelial cell proliferation involved in renal tubule morphogenesis namespace: biological_process def: "Any epithelial cell proliferation that is involved in renal tubule morphogenesis." [GOC:obol] is_a: GO:0050673 ! epithelial cell proliferation intersection_of: GO:0050673 ! epithelial cell proliferation intersection_of: part_of GO:0061333 ! renal tubule morphogenesis relationship: part_of GO:0061333 ! renal tubule morphogenesis created_by: yaf creation_date: 2011-08-12T11:37:29Z [Term] id: GO:2001014 name: regulation of skeletal muscle cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of skeletal muscle cell differentiation." [GOC:obol] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0035914 ! skeletal muscle cell differentiation relationship: regulates GO:0035914 ! skeletal muscle cell differentiation created_by: yaf creation_date: 2011-08-11T08:54:37Z [Term] id: GO:2001015 name: negative regulation of skeletal muscle cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle cell differentiation." [GOC:obol] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:2001014 ! regulation of skeletal muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0035914 ! skeletal muscle cell differentiation relationship: negatively_regulates GO:0035914 ! skeletal muscle cell differentiation created_by: yaf creation_date: 2011-08-11T08:54:41Z [Term] id: GO:2001016 name: positive regulation of skeletal muscle cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of skeletal muscle cell differentiation." [GOC:obol] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:2001014 ! regulation of skeletal muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0035914 ! skeletal muscle cell differentiation relationship: positively_regulates GO:0035914 ! skeletal muscle cell differentiation created_by: yaf creation_date: 2011-08-11T08:54:44Z [Term] id: GO:2001053 name: regulation of mesenchymal cell apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mesenchymal cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] synonym: "regulation of mesenchymal cell apoptosis" NARROW [] is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0097152 ! mesenchymal cell apoptotic process relationship: regulates GO:0097152 ! mesenchymal cell apoptotic process created_by: yaf creation_date: 2011-09-08T02:49:59Z [Term] id: GO:2001054 name: negative regulation of mesenchymal cell apoptotic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] synonym: "negative regulation of mesenchymal cell apoptosis" NARROW [] is_a: GO:0043066 ! negative regulation of apoptotic process is_a: GO:2001053 ! regulation of mesenchymal cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0097152 ! mesenchymal cell apoptotic process relationship: negatively_regulates GO:0097152 ! mesenchymal cell apoptotic process created_by: yaf creation_date: 2011-09-08T02:50:05Z [Term] id: GO:2001055 name: positive regulation of mesenchymal cell apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] synonym: "positive regulation of mesenchymal cell apoptosis" NARROW [] is_a: GO:0043065 ! positive regulation of apoptotic process is_a: GO:2001053 ! regulation of mesenchymal cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0097152 ! mesenchymal cell apoptotic process relationship: positively_regulates GO:0097152 ! mesenchymal cell apoptotic process created_by: yaf creation_date: 2011-09-08T02:50:09Z [Term] id: GO:2001141 name: regulation of RNA biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of RNA biosynthetic process." [GOC:dph] synonym: "regulation of RNA anabolism" EXACT [GOC:obol] synonym: "regulation of RNA biosynthesis" EXACT [GOC:obol] synonym: "regulation of RNA formation" EXACT [GOC:obol] synonym: "regulation of RNA synthesis" EXACT [GOC:obol] is_a: GO:0010556 ! regulation of macromolecule biosynthetic process is_a: GO:0051252 ! regulation of RNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0032774 ! RNA biosynthetic process relationship: regulates GO:0032774 ! RNA biosynthetic process created_by: dph creation_date: 2011-10-17T11:36:25Z [Term] id: GO:2001198 name: regulation of dendritic cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of dendritic cell differentiation." [GOC:obol] is_a: GO:1902105 ! regulation of leukocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0097028 ! dendritic cell differentiation relationship: regulates GO:0097028 ! dendritic cell differentiation created_by: yaf creation_date: 2011-11-04T02:01:27Z [Term] id: GO:2001199 name: negative regulation of dendritic cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell differentiation." [GOC:obol] is_a: GO:1902106 ! negative regulation of leukocyte differentiation is_a: GO:2001198 ! regulation of dendritic cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0097028 ! dendritic cell differentiation relationship: negatively_regulates GO:0097028 ! dendritic cell differentiation created_by: yaf creation_date: 2011-11-04T02:01:33Z [Term] id: GO:2001200 name: positive regulation of dendritic cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of dendritic cell differentiation." [GOC:obol] is_a: GO:1902107 ! positive regulation of leukocyte differentiation is_a: GO:2001198 ! regulation of dendritic cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0097028 ! dendritic cell differentiation relationship: positively_regulates GO:0097028 ! dendritic cell differentiation created_by: yaf creation_date: 2011-11-04T02:01:36Z [Term] id: GO:2001212 name: regulation of vasculogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of vasculogenesis." [GOC:obol] synonym: "regulation of vascular morphogenesis" EXACT [GOC:obol] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001570 ! vasculogenesis relationship: regulates GO:0001570 ! vasculogenesis created_by: yaf creation_date: 2011-11-15T01:22:31Z [Term] id: GO:2001213 name: negative regulation of vasculogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of vasculogenesis." [GOC:obol] synonym: "negative regulation of vascular morphogenesis" EXACT [GOC:obol] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:2001212 ! regulation of vasculogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001570 ! vasculogenesis relationship: negatively_regulates GO:0001570 ! vasculogenesis created_by: yaf creation_date: 2011-11-15T01:22:36Z [Term] id: GO:2001214 name: positive regulation of vasculogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of vasculogenesis." [GOC:obol] synonym: "positive regulation of vascular morphogenesis" EXACT [GOC:obol] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:2001212 ! regulation of vasculogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001570 ! vasculogenesis relationship: positively_regulates GO:0001570 ! vasculogenesis created_by: yaf creation_date: 2011-11-15T01:22:39Z [Term] id: GO:2001222 name: regulation of neuron migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of neuron migration." [GOC:obol] synonym: "regulation of neuron chemotaxis" EXACT [GOC:obol] synonym: "regulation of neuron guidance" RELATED [GOC:obol] synonym: "regulation of neuronal migration" EXACT [GOC:obol] is_a: GO:0030334 ! regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001764 ! neuron migration relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa relationship: regulates GO:0001764 ! neuron migration created_by: kmv creation_date: 2011-11-17T10:01:38Z [Term] id: GO:2001223 name: negative regulation of neuron migration namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of neuron migration." [GOC:obol] synonym: "negative regulation of neuron chemotaxis" EXACT [GOC:obol] synonym: "negative regulation of neuron guidance" RELATED [GOC:obol] synonym: "negative regulation of neuronal migration" EXACT [GOC:obol] is_a: GO:0030336 ! negative regulation of cell migration is_a: GO:2001222 ! regulation of neuron migration intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001764 ! neuron migration relationship: negatively_regulates GO:0001764 ! neuron migration created_by: kmv creation_date: 2011-11-17T10:01:45Z [Term] id: GO:2001224 name: positive regulation of neuron migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of neuron migration." [GOC:obol] synonym: "positive regulation of neuron chemotaxis" EXACT [GOC:obol] synonym: "positive regulation of neuron guidance" RELATED [GOC:obol] synonym: "positive regulation of neuronal migration" EXACT [GOC:obol] is_a: GO:0030335 ! positive regulation of cell migration is_a: GO:2001222 ! regulation of neuron migration intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001764 ! neuron migration relationship: positively_regulates GO:0001764 ! neuron migration created_by: kmv creation_date: 2011-11-17T10:01:49Z [Term] id: GO:2001233 name: regulation of apoptotic signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate or extent of apoptotic signaling pathway." [GOC:mtg_apoptosis] synonym: "regulation of apoptotic signalling pathway" EXACT [GOC:mah] is_a: GO:0009966 ! regulation of signal transduction is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0097190 ! apoptotic signaling pathway relationship: regulates GO:0097190 ! apoptotic signaling pathway created_by: pr creation_date: 2011-11-24T01:20:49Z [Term] id: GO:2001234 name: negative regulation of apoptotic signaling pathway namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic signaling pathway." [GOC:mtg_apoptosis] synonym: "negative regulation of apoptotic signalling pathway" EXACT [GOC:mah] is_a: GO:0009968 ! negative regulation of signal transduction is_a: GO:0043066 ! negative regulation of apoptotic process is_a: GO:2001233 ! regulation of apoptotic signaling pathway intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0097190 ! apoptotic signaling pathway relationship: negatively_regulates GO:0097190 ! apoptotic signaling pathway created_by: pr creation_date: 2011-11-24T01:20:54Z [Term] id: GO:2001235 name: positive regulation of apoptotic signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of apoptotic signaling pathway." [GOC:mtg_apoptosis] synonym: "positive regulation of apoptotic signalling pathway" EXACT [GOC:mah] is_a: GO:0009967 ! positive regulation of signal transduction is_a: GO:0043065 ! positive regulation of apoptotic process is_a: GO:2001233 ! regulation of apoptotic signaling pathway intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0097190 ! apoptotic signaling pathway relationship: positively_regulates GO:0097190 ! apoptotic signaling pathway created_by: pr creation_date: 2011-11-24T01:20:58Z [Term] id: GO:2001251 name: negative regulation of chromosome organization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of chromosome organization." [GOC:obol] synonym: "negative regulation of chromosome organisation" EXACT [GOC:obol] synonym: "negative regulation of chromosome organization and biogenesis" RELATED [GOC:obol] synonym: "negative regulation of maintenance of genome integrity" RELATED [GOC:obol] synonym: "negative regulation of nuclear genome maintenance" RELATED [GOC:obol] is_a: GO:0010639 ! negative regulation of organelle organization is_a: GO:0033044 ! regulation of chromosome organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0051276 ! chromosome organization relationship: negatively_regulates GO:0051276 ! chromosome organization created_by: yaf creation_date: 2011-12-02T02:01:20Z [Term] id: GO:2001252 name: positive regulation of chromosome organization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of chromosome organization." [GOC:obol] synonym: "positive regulation of chromosome organisation" EXACT [GOC:obol] synonym: "positive regulation of chromosome organization and biogenesis" RELATED [GOC:obol] synonym: "positive regulation of maintenance of genome integrity" RELATED [GOC:obol] synonym: "positive regulation of nuclear genome maintenance" RELATED [GOC:obol] is_a: GO:0010638 ! positive regulation of organelle organization is_a: GO:0033044 ! regulation of chromosome organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0051276 ! chromosome organization relationship: positively_regulates GO:0051276 ! chromosome organization created_by: yaf creation_date: 2011-12-02T02:01:26Z [Term] id: IAO:0000027 name: data item def: "An information content entity that is intended to be a truthful statement about something (modulo, e.g., measurement precision or other systematic errors) and is constructed/acquired by a method which reliably tends to produce (approximately) truthful statements." [] is_a: IAO:0000030 ! information content entity property_value: editor_note "2/2/2009 Alan and Bjoern discussing FACS run output data. This is a data item because it is about the cell population. Each element records an event and is typically further composed a set of measurment data items that record the fluorescent intensity stimulated by one of the lasers." xsd:string property_value: editor_note "2009-03-16: data item deliberatly ambiguous: we merged data set and datum to be one entity, not knowing how to define singular versus plural. So data item is more general than datum." xsd:string property_value: editor_note "2009-03-16: removed datum as alternative term as datum specifically refers to singular form, and is thus not an exact synonym." xsd:string property_value: editor_note "2014-03-31: See discussion at http://odontomachus.wordpress.com/2014/03/30/aboutness-objects-propositions/" xsd:string property_value: editor_note "JAR: datum -- well, this will be very tricky to define, but maybe some \ninformation-like stuff that might be put into a computer and that is \nmeant, by someone, to denote and/or to be interpreted by some \nprocess... I would include lists, tables, sentences... I think I might \ndefer to Barry, or to Brian Cantwell Smith\n\nJAR: A data item is an approximately justified approximately true approximate belief" xsd:string property_value: IAO:0000111 "data item" xsd:string property_value: IAO:0000112 "Data items include counts of things, analyte concentrations, and statistical summaries." xsd:string property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 "PERSON: Alan Ruttenberg" xsd:string property_value: IAO:0000117 "PERSON: Chris Stoeckert" xsd:string property_value: IAO:0000117 "PERSON: Jonathan Rees" xsd:string property_value: IAO:0000118 "data" xsd:string [Term] id: IAO:0000028 name: symbol def: "An information content entity that is a mark(s) or character(s) used as a conventional representation of another entity." [] is_a: IAO:0000030 ! information content entity property_value: editor_note "20091104, MC: this needs work and will most probably change" xsd:string property_value: editor_note "2014-03-31: We would like to have a deeper analysis of 'mark' and 'sign' in the future (see https://github.com/information-artifact-ontology/IAO/issues/154)." xsd:string property_value: IAO:0000111 "symbol" xsd:string property_value: IAO:0000112 "a serial number such as \"12324X\"" xsd:string property_value: IAO:0000112 "a stop sign" xsd:string property_value: IAO:0000112 "a written proper name such as \"OBI\"" xsd:string property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 "PERSON: James A. Overton" xsd:string property_value: IAO:0000117 "PERSON: Jonathan Rees" xsd:string property_value: IAO:0000119 "based on Oxford English Dictionary" xsd:string [Term] id: IAO:0000030 name: information content entity def: "A generically dependent continuant that is about some thing." [] is_a: BFO:0000031 ! generically dependent continuant relationship: IAO:0000136 BFO:0000001 ! is about entity property_value: editor_note "2014-03-10: The use of \"thing\" is intended to be general enough to include universals and configurations (see https://groups.google.com/d/msg/information-ontology/GBxvYZCk1oc/-L6B5fSBBTQJ)." xsd:string property_value: editor_note "information_content_entity 'is_encoded_in' some digital_entity in obi before split (040907). information_content_entity 'is_encoded_in' some physical_document in obi before split (040907).\n\nPrevious. An information content entity is a non-realizable information entity that 'is encoded in' some digital or physical entity." xsd:string property_value: IAO:0000111 "information content entity" xsd:string property_value: IAO:0000112 "Examples of information content entites include journal articles, data, graphical layouts, and graphs." xsd:string property_value: IAO:0000114 IAO:0000122 property_value: IAO:0000117 "PERSON: Chris Stoeckert" xsd:string property_value: IAO:0000119 "OBI_0000142" xsd:string [Term] id: IAO:0000078 name: curation status specification def: "The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value." [] is_a: IAO:0000102 ! data about an ontology part property_value: editor_note "Better to represent curation as a process with parts and then relate labels to that process (in IAO meeting)" xsd:string property_value: IAO:0000111 "curation status specification" xsd:string property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 "PERSON:Bill Bug" xsd:string property_value: IAO:0000119 "GROUP:OBI:" xsd:string property_value: IAO:0000119 "OBI_0000266" xsd:string [Term] id: IAO:0000102 name: data about an ontology part def: "Data about an ontology part is a data item about a part of an ontology, for example a term" [] is_a: IAO:0000027 ! data item property_value: IAO:0000111 "data about an ontology part" xsd:string property_value: IAO:0000117 "Person:Alan Ruttenberg" xsd:string [Term] id: IAO:0000225 name: obsolescence reason specification def: "The reason for which a term has been deprecated. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value." [] is_a: IAO:0000102 ! data about an ontology part property_value: editor_note "The creation of this class has been inspired in part by Werner Ceusters' paper, Applying evolutionary terminology auditing to the Gene Ontology." xsd:string property_value: IAO:0000111 "obsolescence reason specification" xsd:string property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 "PERSON: Alan Ruttenberg" xsd:string property_value: IAO:0000117 "PERSON: Melanie Courtot" xsd:string [Term] id: IAO:0000409 name: denotator type def: "A denotator type indicates how a term should be interpreted from an ontological perspective." [] is_a: IAO:0000102 ! data about an ontology part property_value: IAO:0000111 "denotator type" xsd:string property_value: IAO:0000112 "The Basic Formal Ontology ontology makes a distinction between Universals and defined classes, where the formal are \"natural kinds\" and the latter arbitrary collections of entities." xsd:string property_value: IAO:0000117 "Alan Ruttenberg" xsd:string property_value: IAO:0000119 "Barry Smith, Werner Ceusters" xsd:string [Term] id: IAO:0000577 name: centrally registered identifier symbol def: "A symbol that is part of a CRID and that is sufficient to look up a record from the CRID's registry." [] is_a: IAO:0000028 ! symbol relationship: part_of IAO:0000578 ! centrally registered identifier property_value: IAO:0000112 "The sentence \"The article has Pubmed ID 12345.\" contains a CRID that has two parts: one part is the CRID symbol, which is '12345'; the other part denotes the CRID registry, which is Pubmed." xsd:string property_value: IAO:0000114 IAO:0000120 property_value: IAO:0000117 "PERSON: Alan Ruttenberg" xsd:string property_value: IAO:0000117 "PERSON: Bill Hogan" xsd:string property_value: IAO:0000117 "PERSON: Bjoern Peters" xsd:string property_value: IAO:0000117 "PERSON: Melanie Courtot" xsd:string property_value: IAO:0000118 "CRID symbol" xsd:string property_value: IAO:0000119 "Original proposal from Bjoern, discussions at IAO calls" xsd:string [Term] id: IAO:0000578 name: centrally registered identifier def: "An information content entity that consists of a CRID symbol and additional information about the CRID registry to which it belongs." [] is_a: IAO:0020000 ! identifier relationship: has_part IAO:0000577 ! centrally registered identifier symbol property_value: editor_note "2014-05-05: In defining this term we take no position on what the CRID denotes. In particular do not assume it denotes a *record* in the CRID registry (since the registry might not have 'records')." xsd:string property_value: editor_note "Alan, IAO call 20101124: potentially the CRID denotes the instance it was associated with during creation." xsd:string property_value: editor_note "Note, IAO call 20101124: URIs are not always CRID, as not centrally registered. We acknowledge that CRID is a subset of a larger identifier class, but this subset fulfills our current needs. OBI PURLs are CRID as they are registered with OCLC. UPCs (Universal Product Codes from AC Nielsen)are not CRID as they are not centrally registered." xsd:string property_value: IAO:0000112 "The sentence \"The article has Pubmed ID 12345.\" contains a CRID that has two parts: one part is the CRID symbol, which is '12345'; the other part denotes the CRID registry, which is Pubmed." xsd:string property_value: IAO:0000114 IAO:0000120 property_value: IAO:0000117 "PERSON: Alan Ruttenberg" xsd:string property_value: IAO:0000117 "PERSON: Bill Hogan" xsd:string property_value: IAO:0000117 "PERSON: Bjoern Peters" xsd:string property_value: IAO:0000117 "PERSON: Melanie Courtot" xsd:string property_value: IAO:0000118 "CRID" xsd:string property_value: IAO:0000119 "Original proposal from Bjoern, discussions at IAO calls" xsd:string [Term] id: IAO:0000579 name: centrally registered identifier registry def: "A code set of CRID records, each consisting of a CRID symbol and additional information which was recorded in the code set through an assigning a centrally registered identifier process." [] is_a: IAO:0020020 ! code set property_value: IAO:0000112 "PubMed is a CRID registry. It has a code set of PubMed identifiers associated with journal articles. " xsd:string property_value: IAO:0000114 IAO:0000120 property_value: IAO:0000117 "Justin Whorton" xsd:string property_value: IAO:0000117 "PERSON: Alan Ruttenberg" xsd:string property_value: IAO:0000117 "PERSON: Bill Hogan" xsd:string property_value: IAO:0000117 "PERSON: Bjoern Peters" xsd:string property_value: IAO:0000117 "PERSON: Melanie Courtot" xsd:string property_value: IAO:0000118 "CRID registry" xsd:string property_value: IAO:0000119 "Original proposal from Bjoern, discussions at IAO calls" xsd:string property_value: IAO:0000233 "https://github.com/information-artifact-ontology/IAO/issues/237" xsd:string [Term] id: IAO:0020000 name: identifier def: "An information content entity that is the outcome of a dubbing process and is used to refer to one instance of entity shared by a group of people to refer to that individual entity." [] comment: Sep 29, 2016: The current definition has been amended from the previous version: "A proper name is an information content entity that is the outcome of a dubbing process and is used to refer to one instance of entity shared by a group of people to refer to that individual entity." to more accuratly reflect the necessary and sufficient condition on the class. (MB) is_a: IAO:0000030 ! information content entity intersection_of: IAO:0000030 ! information content entity intersection_of: IAO:0000219 BFO:0000001 ! denotes entity intersection_of: OBI:0000312 IAO:0020010 ! is_specified_output_of identifier creating process relationship: IAO:0000219 BFO:0000001 ! denotes entity relationship: OBI:0000312 IAO:0020010 ! is_specified_output_of identifier creating process property_value: dc-creator "Mathias Brochhausen" xsd:string property_value: IAO:0000111 "identifier" xsd:string property_value: IAO:0000117 "Justin Whorton" xsd:string property_value: IAO:0000117 "Mathias Brochhausen" xsd:string property_value: IAO:0000118 "proper name" xsd:string property_value: IAO:0000233 "https://github.com/information-artifact-ontology/IAO/issues/237" xsd:string [Term] id: IAO:0020010 name: identifier creating process def: "A planned process that provides a reference to an individual entity shared by a group of subscribers to refer to that individual entity." [] is_a: OBI:0000011 ! planned process intersection_of: OBI:0000011 ! planned process intersection_of: OBI:0000299 IAO:0020000 ! has_specified_output identifier relationship: OBI:0000299 IAO:0020000 ! has_specified_output identifier property_value: dc-creator "Mathias Brochhausen" xsd:string property_value: IAO:0000117 "Justin Whorton" xsd:string property_value: IAO:0000117 "Mathias Brochhausen" xsd:string property_value: IAO:0000118 "dubbing process" xsd:string property_value: IAO:0000118 "naming" xsd:string property_value: IAO:0000233 "https://github.com/information-artifact-ontology/IAO/issues/237" xsd:string [Term] id: IAO:0020020 name: code set def: "An information content entity that is a collection of other information content entities that has been created to identify or annotate things in a specified domain, and where the intention of its creators is that the collection has a one-to-one correspondence with those things." [] comment: Code sets might include non-entities/things (e.g. missing thumbs). comment: Does not imply absence vs. presence of any taxonomy. comment: Does not imply that aggregated entities denote particulars, universals, or defined classes (a.k.a. attributive collections) or even that they denote only one of these three types of entities. comment: Each aggregated entity is often (but not necessarily) associated with a text string—variously called a “description,” “name,” “title,” or “label”—that helps humans reach the target of denotation.\n\nWhen there is no such string, it is almost always because the entities take the form of human language words. For example, a “sex” or “gender” code set could contain “MALE” and “FEMALE,” or even “M” and “F” (by convention, we understand what these mean). comment: For each given domain, there can potentially exist multiple code sets. The multiplicity of code sets is partially due to the different specific purposes of those code sets. comment: For National Drug Codes (NDCs) and similar code sets, there doesn’t even have to be a single, fully-concretized copy somewhere (for example, for NDCs there is no centralized database or repository where they all live as one instance of concretization of code set). The code set can be “distributively” concretized. This seems like an unusual exception, but it also likely applies to Universal Product Codes (UPCs) and their follow on Global Trade Item Numbers (GTINs). comment: Many code sets are created for a specific purpose in addition to merely identifying or annotating core ideas of a specified domain. comment: The information content entities do not denote each other. is_a: IAO:0000030 ! information content entity relationship: has_part IAO:0020000 ! identifier property_value: IAO:0000117 "Alan Ruttenberg" xsd:string property_value: IAO:0000117 "Justin Whorton" xsd:string property_value: IAO:0000117 "Mathias Brochhausen" xsd:string property_value: IAO:0000118 "code map" xsd:string property_value: IAO:0000118 "code system" xsd:string property_value: IAO:0000118 "codeset" xsd:string property_value: IAO:0000118 "coding system" xsd:string property_value: IAO:0000118 "controlled vocabulary" xsd:string property_value: IAO:0000233 "https://github.com/information-artifact-ontology/IAO/issues/237" xsd:string property_value: x_1.1:contributor "Alan Ruttenberg" xsd:string property_value: x_1.1:contributor "Clint Dowland" xsd:string property_value: x_1.1:contributor "Matt Diller" xsd:string property_value: x_1.1:contributor "Sarah Bost" xsd:string property_value: x_1.1:contributor "William R. Hogan" xsd:string [Term] id: NBO:0000001 name: body part movement namespace: behavior_ontology def: "A change of place or position of part of an organism that does not involve the entire organism [NBO:SMAC]" [] synonym: "stationary movement" EXACT [] is_a: NBO:0000338 ! kinesthetic behavior property_value: x_1.1:date "2011-04-14T01:03:39Z" xsd:string created_by: George Gkoutos [Term] id: NBO:0000007 name: mouth movement namespace: behavior_ontology def: "The act of moving any of the tissues and hard structures surrounding the mouth other than teeth, jaws or filter structures [NBO:AC]" [] synonym: "mouth part movement" NARROW [] synonym: "other moved mouth parts" NARROW [] is_a: NBO:0000001 ! body part movement property_value: x_1.1:date "2011-04-14T01:03:39Z" xsd:string created_by: George Gkoutos [Term] id: NBO:0000073 name: chewing namespace: behavior_ontology def: "The act of repeated grinding, tearing, and or crushing with teeth or jaws [NBO:SMAC]" [] synonym: "chew" EXACT [] synonym: "gnaw" EXACT [] synonym: "mastication" EXACT [] is_a: NBO:0000747 ! jaw movement property_value: x_1.1:date "2011-04-14T01:20:02Z" xsd:string created_by: George Gkoutos [Term] id: NBO:0000313 name: behavior process namespace: behavior_ontology alt_id: NBO:0000000 def: "\"The action, reaction, or performance of an organism in response to external or internal stimuli.\" [GO:GO\\:0007610]" [] synonym: "behavior" EXACT [] synonym: "behaviour" EXACT [] xref: GO:0007610 is_a: GO:0007610 ! behavior property_value: x_1.1:date "2011-04-05T09:53:10Z" xsd:string created_by: George Gkoutos [Term] id: NBO:0000338 name: kinesthetic behavior namespace: behavior_ontology def: "\"Movement behavior of the body or its parts.\"" [] is_a: NBO:0000313 ! behavior process property_value: x_1.1:date "2011-04-05T02:08:47Z" xsd:string created_by: George Gkoutos [Term] id: NBO:0000747 name: jaw movement namespace: behavior_ontology is_a: NBO:0000007 ! mouth movement property_value: x_1.1:date "2012-03-17T09:51:17Z" xsd:string created_by: gkoutos [Term] id: NBO:0001786 name: regulation of behavior def: "\"Any process that modulates the frequency, rate or extent of behavior, the specific actions or reactions of an organism in response to external or internal stimuli.\" [GO:0050795]" [] xref: GO:0050795 is_a: NBO:0000313 ! behavior process relationship: regulates NBO:0000313 ! behavior process created_by: George Gkoutos [Term] id: NCBITaxon:1 name: root namespace: ncbi_taxonomy synonym: "all" RELATED synonym [] xref: GC_ID:1 xref: PMID:30365038 xref: PMID:32761142 [Term] id: NCBITaxon:10066 name: Muridae namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:15371245 is_a: NCBITaxon:337687 ! Muroidea property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:10088 name: Mus namespace: ncbi_taxonomy synonym: "mice" EXACT OMO:0003003 [] synonym: "mouse" EXACT OMO:0003003 [] synonym: "Mus" EXACT scientific_name [] xref: GC_ID:1 is_a: NCBITaxon:39107 ! Murinae disjoint_from: NCBITaxon:10114 ! Rattus property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:10090 name: Mus musculus namespace: ncbi_taxonomy alt_id: NCBITaxon:85055 synonym: "house mouse" EXACT genbank_common_name [] synonym: "mouse" EXACT OMO:0003003 [] xref: GC_ID:1 is_a: NCBITaxon:862507 ! Mus property_value: has_rank NCBITaxon:species [Term] id: NCBITaxon:10114 name: Rattus namespace: ncbi_taxonomy synonym: "rat" EXACT OMO:0003003 [] synonym: "rats" EXACT OMO:0003003 [] xref: GC_ID:1 is_a: NCBITaxon:39107 ! Murinae property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:105389 name: Sedentaria namespace: ncbi_taxonomy synonym: "Palpata" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:6341 ! Polychaeta property_value: has_rank NCBITaxon:subclass [Term] id: NCBITaxon:105391 name: Canalipalpata namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:105389 ! Sedentaria property_value: has_rank NCBITaxon:infraclass [Term] id: NCBITaxon:110814 name: Xenoturbellida namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:1312402 ! Xenacoelomorpha disjoint_from: NCBITaxon:147099 ! Acoelomorpha property_value: has_rank NCBITaxon:subphylum [Term] id: NCBITaxon:110815 name: Xenoturbella namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:1547233 ! Xenoturbellidae property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:117565 name: Myxini namespace: ncbi_taxonomy synonym: "Agnatha" RELATED in_part [] synonym: "fish" EXACT OMO:0003003 [] synonym: "fishes" EXACT OMO:0003003 [] synonym: "Hyperotreti" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:1476529 ! Cyclostomata property_value: has_rank NCBITaxon:class [Term] id: NCBITaxon:117570 name: Teleostomi namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:7776 ! Gnathostomata disjoint_from: NCBITaxon:7777 ! Chondrichthyes property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:117571 name: Euteleostomi namespace: ncbi_taxonomy alt_id: NCBITaxon:40673 synonym: "bony vertebrates" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:117570 ! Teleostomi property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:119089 name: Chromadorea namespace: ncbi_taxonomy alt_id: NCBITaxon:27837 synonym: "Adenophorea" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:6231 ! Nematoda property_value: has_rank NCBITaxon:class [Term] id: NCBITaxon:1206794 name: Ecdysozoa namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:33317 ! Protostomia disjoint_from: NCBITaxon:2697495 ! Spiralia property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:1206795 name: Lophotrochozoa namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:2697495 ! Spiralia property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:123365 name: Neoteleostei namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:1489388 ! Euteleosteomorpha property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:123366 name: Eurypterygia namespace: ncbi_taxonomy synonym: "Eurypterygii" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:123365 ! Neoteleostei property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:123367 name: Ctenosquamata namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:123366 ! Eurypterygia property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:123368 name: Acanthomorphata namespace: ncbi_taxonomy synonym: "Acanthomorpha" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:123367 ! Ctenosquamata property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:123369 name: Euacanthomorphacea namespace: ncbi_taxonomy synonym: "Euacanthomorpha" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:123368 ! Acanthomorphata property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:124129 name: Acipenserinae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:7900 ! Acipenseridae property_value: has_rank NCBITaxon:subfamily [Term] id: NCBITaxon:124130 name: Acipenserini namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:124129 ! Acipenserinae property_value: has_rank NCBITaxon:tribe [Term] id: NCBITaxon:131209 name: Zygnemophyceae namespace: ncbi_taxonomy synonym: "Conjugatophyceae" RELATED synonym [] synonym: "Gamophyceae" RELATED synonym [] synonym: "Gamophyta" RELATED synonym [] synonym: "gamophytes" EXACT OMO:0003003 [] synonym: "Zygnematophyceae" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:131221 ! Streptophytina disjoint_from: NCBITaxon:3193 ! Embryophyta property_value: has_rank NCBITaxon:class [Term] id: NCBITaxon:131221 name: Streptophytina namespace: ncbi_taxonomy synonym: "Charophyta/Embryophyta group" RELATED synonym [] synonym: "charophyte/embryophyte group" EXACT equivalent_name [] xref: GC_ID:1 is_a: NCBITaxon:35493 ! Streptophyta property_value: has_rank NCBITaxon:subphylum [Term] id: NCBITaxon:1312402 name: Xenacoelomorpha namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:33213 ! Bilateria disjoint_from: NCBITaxon:33317 ! Protostomia disjoint_from: NCBITaxon:33511 ! Deuterostomia property_value: has_rank NCBITaxon:phylum [Term] id: NCBITaxon:131567 name: cellular organisms namespace: ncbi_taxonomy synonym: "biota" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:1 ! root [Term] id: NCBITaxon:1329799 name: Archelosauria namespace: ncbi_taxonomy synonym: "Archosauria-Testudines" RELATED synonym [] synonym: "Testudines + Archosauria group" RELATED synonym [] xref: GC_ID:1 xref: PMID:22839753 xref: PMID:25450099 is_a: NCBITaxon:32561 ! Sauria property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:1338369 name: Dipnotetrapodomorpha namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:8287 ! Sarcopterygii property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:142796 name: Eumycetozoa namespace: ncbi_taxonomy synonym: "Eumycetozoa Zopf, 1884" RELATED synonym [] synonym: "Mycetozoa" RELATED synonym [] synonym: "mycetozoans" RELATED synonym [] xref: GC_ID:1 xref: PMID:11062127 xref: PMID:9342353 is_a: NCBITaxon:2605435 ! Evosea property_value: has_rank NCBITaxon:class [Term] id: NCBITaxon:1437010 name: Boreoeutheria namespace: ncbi_taxonomy synonym: "Boreotheria" RELATED synonym [] xref: GC_ID:1 xref: PMID:11743200 xref: PMID:11791233 is_a: NCBITaxon:9347 ! Eutheria property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:1437180 name: Acrogymnospermae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:58024 ! Spermatophyta disjoint_from: NCBITaxon:3398 ! Magnoliopsida property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:1445966 name: Gnetidae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:3372 ! Gnetopsida property_value: has_rank NCBITaxon:subclass [Term] id: NCBITaxon:147099 name: Acoelomorpha namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:1312402 ! Xenacoelomorpha property_value: has_rank NCBITaxon:subphylum [Term] id: NCBITaxon:147537 name: Saccharomycotina namespace: ncbi_taxonomy synonym: "true yeasts" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:716545 ! saccharomyceta property_value: has_rank NCBITaxon:subphylum [Term] id: NCBITaxon:147554 name: Schizosaccharomycetes namespace: ncbi_taxonomy synonym: "Archiascomycota" RELATED in_part [] xref: GC_ID:1 is_a: NCBITaxon:451866 ! Taphrinomycotina property_value: has_rank NCBITaxon:class [Term] id: NCBITaxon:1476529 name: Cyclostomata namespace: ncbi_taxonomy synonym: "Agnatha" RELATED synonym [] synonym: "jawless vertebrates" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:7742 ! Vertebrata disjoint_from: NCBITaxon:7776 ! Gnathostomata property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:1489341 name: Osteoglossocephalai namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:32443 ! Teleostei property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:1489388 name: Euteleosteomorpha namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:186625 ! Clupeocephala disjoint_from: NCBITaxon:186634 ! Otomorpha property_value: has_rank NCBITaxon:cohort [Term] id: NCBITaxon:1489872 name: Percomorphaceae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:123369 ! Euacanthomorphacea property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:1489922 name: Eupercaria namespace: ncbi_taxonomy synonym: "Percomorpharia" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:1489872 ! Percomorphaceae property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:1547233 name: Xenoturbellidae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:110814 ! Xenoturbellida property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:186622 name: Acipenseroidei namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:7899 ! Acipenseriformes property_value: has_rank NCBITaxon:suborder [Term] id: NCBITaxon:186623 name: Actinopteri namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:7898 ! Actinopterygii property_value: has_rank NCBITaxon:class [Term] id: NCBITaxon:186625 name: Clupeocephala namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:1489341 ! Osteoglossocephalai [Term] id: NCBITaxon:186626 name: Otophysi namespace: ncbi_taxonomy synonym: "Otophysa" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:32519 ! Ostariophysi property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:186627 name: Cypriniphysae namespace: ncbi_taxonomy synonym: "Cypriniphysi" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:186626 ! Otophysi property_value: has_rank NCBITaxon:superorder [Term] id: NCBITaxon:186634 name: Otomorpha namespace: ncbi_taxonomy synonym: "Ostarioclupeomorpha" RELATED synonym [] synonym: "Otocephala" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:186625 ! Clupeocephala property_value: has_rank NCBITaxon:cohort [Term] id: NCBITaxon:1963758 name: Myomorpha namespace: ncbi_taxonomy synonym: "mice and others" EXACT genbank_common_name [] synonym: "Sciurognathi" RELATED in_part [] xref: GC_ID:1 is_a: NCBITaxon:9989 ! Rodentia property_value: has_rank NCBITaxon:suborder [Term] id: NCBITaxon:197562 name: Pancrustacea namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:10874751 xref: PMID:11557979 is_a: NCBITaxon:197563 ! Mandibulata property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:197563 name: Mandibulata namespace: ncbi_taxonomy synonym: "mandibulates" EXACT OMO:0003003 [] xref: GC_ID:1 xref: PMID:11557979 xref: PMID:9727836 is_a: NCBITaxon:6656 ! Arthropoda property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:2 name: Bacteria namespace: ncbi_taxonomy synonym: "bacteria" RELATED blast_name [] synonym: "eubacteria" EXACT genbank_common_name [] synonym: "Monera" RELATED in_part [] synonym: "Procaryotae" RELATED in_part [] synonym: "Prokaryota" RELATED in_part [] synonym: "Prokaryotae" RELATED in_part [] synonym: "prokaryote" RELATED in_part [] synonym: "prokaryotes" RELATED in_part [] xref: GC_ID:11 xref: PMID:10425795 xref: PMID:10425796 xref: PMID:10425797 xref: PMID:10490293 xref: PMID:10843050 xref: PMID:10939651 xref: PMID:10939673 xref: PMID:10939677 xref: PMID:11211268 xref: PMID:11321083 xref: PMID:11321113 xref: PMID:11411719 xref: PMID:11540071 xref: PMID:11542017 xref: PMID:11542087 xref: PMID:11760965 xref: PMID:12054223 xref: PMID:2112744 xref: PMID:270744 xref: PMID:32628106 xref: PMID:36748408 xref: PMID:7520741 xref: PMID:8123559 xref: PMID:8186100 xref: PMID:8590690 xref: PMID:9103655 xref: PMID:9336922 is_a: NCBITaxon:131567 ! cellular organisms disjoint_from: NCBITaxon:2157 ! Archaea disjoint_from: NCBITaxon:2759 ! Eukaryota property_value: has_rank NCBITaxon:superkingdom [Term] id: NCBITaxon:2058185 name: Dictyosteliaceae namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:29367151 is_a: NCBITaxon:2058949 ! Dictyosteliales property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:2058949 name: Dictyosteliales namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:29367151 is_a: NCBITaxon:33083 ! Dictyostelia property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:207598 name: Homininae namespace: ncbi_taxonomy synonym: "Homo/Pan/Gorilla group" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:9604 ! Hominidae property_value: has_rank NCBITaxon:subfamily [Term] id: NCBITaxon:2157 name: Archaea namespace: ncbi_taxonomy synonym: "archaea" RELATED blast_name [] synonym: "Archaebacteria" RELATED synonym [] synonym: "Mendosicutes" RELATED synonym [] synonym: "Metabacteria" RELATED synonym [] synonym: "Monera" RELATED in_part [] synonym: "Procaryotae" RELATED in_part [] synonym: "Prokaryota" RELATED in_part [] synonym: "Prokaryotae" RELATED in_part [] synonym: "prokaryote" RELATED in_part [] synonym: "prokaryotes" RELATED in_part [] xref: GC_ID:11 xref: PMID:10425795 xref: PMID:10425796 xref: PMID:10425797 xref: PMID:10490293 xref: PMID:10843050 xref: PMID:10939651 xref: PMID:10939673 xref: PMID:10939677 xref: PMID:11211268 xref: PMID:11321083 xref: PMID:11321113 xref: PMID:11411719 xref: PMID:11540071 xref: PMID:11541975 xref: PMID:11542064 xref: PMID:11542149 xref: PMID:11760965 xref: PMID:12054223 xref: PMID:2112744 xref: PMID:25527841 xref: PMID:270744 xref: PMID:32628106 xref: PMID:36748408 xref: PMID:8123559 xref: PMID:8590690 xref: PMID:9103655 xref: PMID:9336922 is_a: NCBITaxon:131567 ! cellular organisms disjoint_from: NCBITaxon:2759 ! Eukaryota property_value: has_rank NCBITaxon:superkingdom [Term] id: NCBITaxon:2301116 name: Rhabditina namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:6236 ! Rhabditida property_value: has_rank NCBITaxon:suborder [Term] id: NCBITaxon:2301119 name: Rhabditomorpha namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:2301116 ! Rhabditina property_value: has_rank NCBITaxon:infraorder [Term] id: NCBITaxon:2605435 name: Evosea namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:554915 ! Amoebozoa property_value: has_rank NCBITaxon:phylum [Term] id: NCBITaxon:2611352 name: Discoba namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:2759 ! Eukaryota disjoint_from: NCBITaxon:2698737 ! Sar disjoint_from: NCBITaxon:33090 ! Viridiplantae disjoint_from: NCBITaxon:33154 ! Opisthokonta disjoint_from: NCBITaxon:38254 ! Glaucocystophyceae disjoint_from: NCBITaxon:554915 ! Amoebozoa property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:262014 name: Xenopus namespace: ncbi_taxonomy synonym: "Xenopus" EXACT scientific_name [] xref: GC_ID:1 is_a: NCBITaxon:8353 ! Xenopus property_value: has_rank NCBITaxon:subgenus [Term] id: NCBITaxon:2684882 name: Zygnematophycidae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:131209 ! Zygnemophyceae property_value: has_rank NCBITaxon:subclass [Term] id: NCBITaxon:2697495 name: Spiralia namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:33317 ! Protostomia property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:2698737 name: Sar namespace: ncbi_taxonomy synonym: "SAR supergroup" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:2759 ! Eukaryota disjoint_from: NCBITaxon:33090 ! Viridiplantae disjoint_from: NCBITaxon:33154 ! Opisthokonta disjoint_from: NCBITaxon:38254 ! Glaucocystophyceae disjoint_from: NCBITaxon:554915 ! Amoebozoa property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:2743709 name: Danionidae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:30727 ! Cyprinoidei property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:2743711 name: Danioninae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:2743709 ! Danionidae property_value: has_rank NCBITaxon:subfamily [Term] id: NCBITaxon:2759 name: Eukaryota namespace: ncbi_taxonomy synonym: "Eucarya" RELATED synonym [] synonym: "Eucaryotae" RELATED synonym [] synonym: "eucaryotes" EXACT genbank_common_name [] synonym: "euk-" RELATED PRO-short-label [PRO:DAN] synonym: "Eukarya" RELATED synonym [] synonym: "Eukaryotae" RELATED synonym [] synonym: "eukaryotes" EXACT OMO:0003003 [] synonym: "eukaryotes" RELATED blast_name [] xref: GC_ID:1 xref: PMID:23020233 xref: PMID:30257078 is_a: NCBITaxon:131567 ! cellular organisms is_a: OBI:0100026 ! organism property_value: has_rank NCBITaxon:superkingdom [Term] id: NCBITaxon:30319 name: Pipoidea namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:8342 ! Anura property_value: has_rank NCBITaxon:superfamily [Term] id: NCBITaxon:30727 name: Cyprinoidei namespace: ncbi_taxonomy synonym: "Cyprinoidea" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:7952 ! Cypriniformes property_value: has_rank NCBITaxon:suborder [Term] id: NCBITaxon:31022 name: Tetraodontiformes namespace: ncbi_taxonomy synonym: "pufferfishes and others" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:1489922 ! Eupercaria property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:31028 name: Tetraodontoidei namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:31022 ! Tetraodontiformes property_value: has_rank NCBITaxon:suborder [Term] id: NCBITaxon:31031 name: Tetraodontidae namespace: ncbi_taxonomy synonym: "puffer fishes" EXACT OMO:0003003 [] synonym: "puffers" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:32517 ! Tetradontoidea property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:31032 name: Takifugu namespace: ncbi_taxonomy synonym: "Fugu" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:31031 ! Tetraodontidae property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:31033 name: Takifugu rubripes namespace: ncbi_taxonomy synonym: "Fugu rubripes" RELATED synonym [] synonym: "Sphaeroides rubripes" RELATED synonym [] synonym: "Tetraodon rubripes" RELATED synonym [] synonym: "tiger puffer" EXACT OMO:0003003 [] synonym: "torafugu" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:31032 ! Takifugu property_value: has_rank NCBITaxon:species [Term] id: NCBITaxon:314146 name: Euarchontoglires namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:11214319 xref: PMID:12082125 xref: PMID:12878460 xref: PMID:15522813 is_a: NCBITaxon:1437010 ! Boreoeutheria property_value: has_rank NCBITaxon:superorder [Term] id: NCBITaxon:314147 name: Glires namespace: ncbi_taxonomy synonym: "Rodents and rabbits" EXACT genbank_common_name [] xref: GC_ID:1 xref: PMID:11214319 xref: PMID:12082125 xref: PMID:15522813 is_a: NCBITaxon:314146 ! Euarchontoglires disjoint_from: NCBITaxon:9443 ! Primates property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:314293 name: Simiiformes namespace: ncbi_taxonomy synonym: "Anthropoidea" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:376913 ! Haplorrhini property_value: has_rank NCBITaxon:infraorder [Term] id: NCBITaxon:314295 name: Hominoidea namespace: ncbi_taxonomy synonym: "ape" EXACT OMO:0003003 [] synonym: "apes" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:9526 ! Catarrhini property_value: has_rank NCBITaxon:superfamily [Term] id: NCBITaxon:3176 name: Zygnematales namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:2684882 ! Zygnematophycidae property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:3193 name: Embryophyta namespace: ncbi_taxonomy synonym: "higher plants" EXACT OMO:0003003 [] synonym: "land plants" EXACT OMO:0003003 [] synonym: "land plants" RELATED blast_name [] synonym: "plants" EXACT OMO:0003003 [] xref: GC_ID:1 is_a: NCBITaxon:131221 ! Streptophytina property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:32341 name: Sophophora namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:7215 ! Drosophila property_value: has_rank NCBITaxon:subgenus [Term] id: NCBITaxon:32346 name: melanogaster group namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:32341 ! Sophophora property_value: has_rank NCBITaxon:species_group [Term] id: NCBITaxon:32351 name: melanogaster subgroup namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:32346 ! melanogaster group property_value: has_rank NCBITaxon:species_subgroup [Term] id: NCBITaxon:32440 name: Chondrostei namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:186623 ! Actinopteri disjoint_from: NCBITaxon:41665 ! Neopterygii property_value: has_rank NCBITaxon:subclass [Term] id: NCBITaxon:32443 name: Teleostei namespace: ncbi_taxonomy synonym: "teleost fishes" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:41665 ! Neopterygii property_value: has_rank NCBITaxon:infraclass [Term] id: NCBITaxon:32517 name: Tetradontoidea namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:31028 ! Tetraodontoidei property_value: has_rank NCBITaxon:superfamily [Term] id: NCBITaxon:32519 name: Ostariophysi namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:186634 ! Otomorpha property_value: has_rank NCBITaxon:subcohort [Term] id: NCBITaxon:32523 name: Tetrapoda namespace: ncbi_taxonomy synonym: "tetrapods" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:1338369 ! Dipnotetrapodomorpha disjoint_from: NCBITaxon:7878 ! Dipnomorpha property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:32524 name: Amniota namespace: ncbi_taxonomy synonym: "amniotes" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:32523 ! Tetrapoda disjoint_from: NCBITaxon:8292 ! Amphibia property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:32525 name: Theria namespace: ncbi_taxonomy synonym: "Theria" EXACT scientific_name [] xref: GC_ID:1 is_a: NCBITaxon:40674 ! Mammalia disjoint_from: NCBITaxon:9254 ! Prototheria property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:32561 name: Sauria namespace: ncbi_taxonomy synonym: "Diapsida" RELATED synonym [] synonym: "diapsids" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:8457 ! Sauropsida property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:33083 name: Dictyostelia namespace: ncbi_taxonomy synonym: "cellular slime molds" RELATED blast_name [] synonym: "dictyostelid cellular slime molds" EXACT genbank_common_name [] synonym: "Dictyostelida" RELATED synonym [] synonym: "Dictyostelids" RELATED synonym [] synonym: "Dictyosteliida" RELATED synonym [] xref: GC_ID:1 xref: PMID:11062127 xref: PMID:29367151 xref: PMID:9342353 is_a: NCBITaxon:142796 ! Eumycetozoa property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:33090 name: Viridiplantae namespace: ncbi_taxonomy synonym: "Chlorobionta" RELATED synonym [] synonym: "Chlorophyta/Embryophyta group" EXACT equivalent_name [] synonym: "chlorophyte/embryophyte group" EXACT equivalent_name [] synonym: "Chloroplastida" RELATED synonym [] synonym: "green plants" EXACT OMO:0003003 [] synonym: "green plants" RELATED blast_name [] xref: GC_ID:1 xref: PMID:16248873 xref: PMID:30257078 is_a: NCBITaxon:2759 ! Eukaryota disjoint_from: NCBITaxon:33154 ! Opisthokonta disjoint_from: NCBITaxon:38254 ! Glaucocystophyceae disjoint_from: NCBITaxon:554915 ! Amoebozoa property_value: has_rank NCBITaxon:kingdom [Term] id: NCBITaxon:3312 name: Coniferophyta namespace: ncbi_taxonomy synonym: "conifers" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:1437180 ! Acrogymnospermae disjoint_from: NCBITaxon:3372 ! Gnetopsida property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:33154 name: Opisthokonta namespace: ncbi_taxonomy synonym: "Fungi/Metazoa group" RELATED synonym [] synonym: "opisthokonts" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:2759 ! Eukaryota disjoint_from: NCBITaxon:38254 ! Glaucocystophyceae disjoint_from: NCBITaxon:554915 ! Amoebozoa property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:33208 name: Metazoa namespace: ncbi_taxonomy synonym: "Animalia" RELATED synonym [] synonym: "animals" RELATED blast_name [] synonym: "metazoans" EXACT genbank_common_name [] synonym: "multicellular animals" EXACT OMO:0003003 [] xref: GC_ID:1 is_a: NCBITaxon:33154 ! Opisthokonta disjoint_from: NCBITaxon:4751 ! Fungi property_value: has_rank NCBITaxon:kingdom [Term] id: NCBITaxon:33213 name: Bilateria namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:6072 ! Eumetazoa disjoint_from: NCBITaxon:6073 ! Cnidaria property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:33317 name: Protostomia namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:33213 ! Bilateria disjoint_from: NCBITaxon:33511 ! Deuterostomia property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:33340 name: Neoptera namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:7496 ! Pterygota property_value: has_rank NCBITaxon:infraclass [Term] id: NCBITaxon:33392 name: Endopterygota namespace: ncbi_taxonomy synonym: "Holometabola" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:33340 ! Neoptera property_value: has_rank NCBITaxon:cohort [Term] id: NCBITaxon:33511 name: Deuterostomia namespace: ncbi_taxonomy synonym: "deuterostomes" EXACT OMO:0003003 [] xref: GC_ID:1 is_a: NCBITaxon:33213 ! Bilateria property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:33630 name: Alveolata namespace: ncbi_taxonomy synonym: "alveolates" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:2698737 ! Sar property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:33682 name: Euglenozoa namespace: ncbi_taxonomy synonym: "Euglenozoans" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:2611352 ! Discoba property_value: has_rank NCBITaxon:phylum [Term] id: NCBITaxon:3372 name: Gnetopsida namespace: ncbi_taxonomy synonym: "Chlamydospermopsida" RELATED synonym [] synonym: "Gneticae" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:1437180 ! Acrogymnospermae property_value: has_rank NCBITaxon:class [Term] id: NCBITaxon:337687 name: Muroidea namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:15019624 xref: PMID:15371245 is_a: NCBITaxon:1963758 ! Myomorpha property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:3378 name: Gnetales namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:1445966 ! Gnetidae property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:3398 name: Magnoliopsida namespace: ncbi_taxonomy synonym: "Angiospermae" RELATED synonym [] synonym: "angiosperms" EXACT OMO:0003003 [] synonym: "flowering plants" EXACT genbank_common_name [] synonym: "flowering plants" RELATED blast_name [] synonym: "Magnoliophyta" RELATED synonym [] xref: GC_ID:1 xref: PMID:25249442 is_a: NCBITaxon:58024 ! Spermatophyta property_value: has_rank NCBITaxon:class [Term] id: NCBITaxon:34346 name: Schizosaccharomycetales namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:147554 ! Schizosaccharomycetes property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:35493 name: Streptophyta namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:33090 ! Viridiplantae property_value: has_rank NCBITaxon:phylum [Term] id: NCBITaxon:376913 name: Haplorrhini namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:9443 ! Primates property_value: has_rank NCBITaxon:suborder [Term] id: NCBITaxon:38254 name: Glaucocystophyceae namespace: ncbi_taxonomy synonym: "algae" RELATED in_part [] synonym: "glaucocystophytes" EXACT OMO:0003003 [] synonym: "Glaucophyceae" RELATED synonym [] synonym: "Glaucophyta" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:2759 ! Eukaryota disjoint_from: NCBITaxon:554915 ! Amoebozoa property_value: has_rank NCBITaxon:class [Term] id: NCBITaxon:39107 name: Murinae namespace: ncbi_taxonomy alt_id: NCBITaxon:109679 xref: GC_ID:1 is_a: NCBITaxon:10066 ! Muridae property_value: has_rank NCBITaxon:subfamily [Term] id: NCBITaxon:40674 name: Mammalia namespace: ncbi_taxonomy synonym: "mammals" EXACT genbank_common_name [] synonym: "mammals" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:32524 ! Amniota disjoint_from: NCBITaxon:8457 ! Sauropsida property_value: has_rank NCBITaxon:class [Term] id: NCBITaxon:41324 name: Siboglinidae namespace: ncbi_taxonomy alt_id: NCBITaxon:167797 alt_id: NCBITaxon:27906 alt_id: NCBITaxon:29174 alt_id: NCBITaxon:41329 alt_id: NCBITaxon:54122 alt_id: NCBITaxon:55674 alt_id: NCBITaxon:55678 alt_id: NCBITaxon:6422 synonym: "Frenulata" RELATED synonym [] synonym: "Lamellibrachiidae" RELATED synonym [] synonym: "Obturata" RELATED synonym [] synonym: "Oligobrachiidae" RELATED synonym [] synonym: "Perviata" RELATED synonym [] synonym: "Pogonophora" RELATED synonym [] synonym: "pogonophores" EXACT OMO:0003003 [] synonym: "Polybrachiidae" RELATED synonym [] synonym: "Sclerolinidae" RELATED synonym [] synonym: "tube worms" RELATED blast_name [] synonym: "Vestimentifera" RELATED synonym [] synonym: "vestimentiferans" EXACT OMO:0003003 [] xref: GC_ID:1 is_a: NCBITaxon:6362 ! Sabellida property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:41665 name: Neopterygii namespace: ncbi_taxonomy synonym: "Neopterygi" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:186623 ! Actinopteri property_value: has_rank NCBITaxon:subclass [Term] id: NCBITaxon:41666 name: Batrachia namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:8292 ! Amphibia property_value: has_rank NCBITaxon:superorder [Term] id: NCBITaxon:436486 name: Dinosauria namespace: ncbi_taxonomy synonym: "dinosaur" EXACT OMO:0003003 [] synonym: "dinosaurs" EXACT OMO:0003003 [] xref: GC_ID:1 is_a: NCBITaxon:8492 ! Archosauria property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:436489 name: Saurischia namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:436486 ! Dinosauria property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:436491 name: Theropoda namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:436489 ! Saurischia property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:436492 name: Coelurosauria namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:436491 ! Theropoda property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:43733 name: Muscomorpha namespace: ncbi_taxonomy alt_id: NCBITaxon:43732 synonym: "Asilomorpha" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:7203 ! Brachycera property_value: has_rank NCBITaxon:infraorder [Term] id: NCBITaxon:43738 name: Schizophora namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:480117 ! Cyclorrhapha [Term] id: NCBITaxon:43741 name: Acalyptratae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:43738 ! Schizophora [Term] id: NCBITaxon:43746 name: Ephydroidea namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:43741 ! Acalyptratae property_value: has_rank NCBITaxon:superfamily [Term] id: NCBITaxon:43845 name: Drosophilinae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:7214 ! Drosophilidae property_value: has_rank NCBITaxon:subfamily [Term] id: NCBITaxon:451864 name: Dikarya namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:15689432 xref: PMID:16151185 xref: PMID:17010206 xref: PMID:17051209 xref: PMID:17572334 is_a: NCBITaxon:4751 ! Fungi property_value: has_rank NCBITaxon:subkingdom [Term] id: NCBITaxon:451866 name: Taphrinomycotina namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:4890 ! Ascomycota disjoint_from: NCBITaxon:716545 ! saccharomyceta property_value: has_rank NCBITaxon:subphylum [Term] id: NCBITaxon:46877 name: Drosophilini namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:43845 ! Drosophilinae property_value: has_rank NCBITaxon:tribe [Term] id: NCBITaxon:4751 name: Fungi namespace: ncbi_taxonomy synonym: "fungi" RELATED blast_name [] synonym: "Mycota" RELATED synonym [] xref: GC_ID:1 xref: PMID:11062127 xref: PMID:12684019 is_a: NCBITaxon:33154 ! Opisthokonta property_value: has_rank NCBITaxon:kingdom [Term] id: NCBITaxon:480117 name: Cyclorrhapha namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:480118 ! Eremoneura property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:480118 name: Eremoneura namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:43733 ! Muscomorpha property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:4890 name: Ascomycota namespace: ncbi_taxonomy synonym: "ascomycete fungi" RELATED blast_name [] synonym: "ascomycetes" EXACT genbank_common_name [] synonym: "sac fungi" EXACT OMO:0003003 [] xref: GC_ID:1 xref: PMID:17572334 is_a: NCBITaxon:451864 ! Dikarya property_value: has_rank NCBITaxon:phylum [Term] id: NCBITaxon:4891 name: Saccharomycetes namespace: ncbi_taxonomy synonym: "Hemiascomycetes" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:147537 ! Saccharomycotina property_value: has_rank NCBITaxon:class [Term] id: NCBITaxon:4892 name: Saccharomycetales namespace: ncbi_taxonomy synonym: "budding yeasts" RELATED blast_name [] synonym: "Endomycetales" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:4891 ! Saccharomycetes property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:4893 name: Saccharomycetaceae namespace: ncbi_taxonomy alt_id: NCBITaxon:221665 alt_id: NCBITaxon:44280 xref: GC_ID:1 is_a: NCBITaxon:4892 ! Saccharomycetales property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:4894 name: Schizosaccharomycetaceae namespace: ncbi_taxonomy synonym: "fission yeasts" EXACT genbank_common_name [] synonym: "Schizosaccharomycetoideae" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:34346 ! Schizosaccharomycetales property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:4895 name: Schizosaccharomyces namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:4894 ! Schizosaccharomycetaceae property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:4896 name: Schizosaccharomyces pombe namespace: ncbi_taxonomy alt_id: NCBITaxon:45042 synonym: "fission yeast" EXACT genbank_common_name [] synonym: "Schizosaccharomyces malidevorans" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:4895 ! Schizosaccharomyces property_value: has_rank NCBITaxon:species [Term] id: NCBITaxon:4930 name: Saccharomyces namespace: ncbi_taxonomy alt_id: NCBITaxon:36915 synonym: "Pachytichospora" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:4893 ! Saccharomycetaceae property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:4932 name: Saccharomyces cerevisiae namespace: ncbi_taxonomy alt_id: NCBITaxon:41870 synonym: "baker's yeast" EXACT OMO:0003003 [] synonym: "brewer's yeast" EXACT genbank_common_name [] synonym: "Candida robusta" RELATED synonym [] synonym: "Mycoderma cerevisiae" RELATED synonym [] synonym: "Saccharomyces capensis" RELATED synonym [] synonym: "Saccharomyces cerevisiae 'var. diastaticus'" EXACT equivalent_name [] synonym: "Saccharomyces diastaticus" RELATED synonym [] synonym: "Saccharomyces italicus" RELATED synonym [] synonym: "Saccharomyces oviformis" RELATED synonym [] synonym: "Saccharomyces uvarum var. melibiosus" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:4930 ! Saccharomyces property_value: has_rank NCBITaxon:species [Term] id: NCBITaxon:50557 name: Insecta namespace: ncbi_taxonomy synonym: "insects" RELATED blast_name [] synonym: "true insects" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:6960 ! Hexapoda property_value: has_rank NCBITaxon:class [Term] id: NCBITaxon:554915 name: Amoebozoa namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:23020233 xref: PMID:30257078 is_a: NCBITaxon:2759 ! Eukaryota property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:55879 name: Rhabditoidea namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:2301119 ! Rhabditomorpha property_value: has_rank NCBITaxon:superfamily [Term] id: NCBITaxon:55885 name: Peloderinae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:6243 ! Rhabditidae property_value: has_rank NCBITaxon:subfamily [Term] id: NCBITaxon:5782 name: Dictyostelium namespace: ncbi_taxonomy synonym: "Hyalostilbum" RELATED synonym [] xref: GC_ID:1 xref: PMID:29367151 is_a: NCBITaxon:2058185 ! Dictyosteliaceae property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:58023 name: Tracheophyta namespace: ncbi_taxonomy synonym: "vascular plants" EXACT OMO:0003003 [] synonym: "vascular plants" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:3193 ! Embryophyta property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:58024 name: Spermatophyta namespace: ncbi_taxonomy synonym: "seed plants" EXACT OMO:0003003 [] synonym: "seed plants" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:78536 ! Euphyllophyta property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:6040 name: Porifera namespace: ncbi_taxonomy synonym: "Parazoa" RELATED synonym [] synonym: "sponges" EXACT genbank_common_name [] synonym: "sponges" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:33208 ! Metazoa disjoint_from: NCBITaxon:6072 ! Eumetazoa property_value: has_rank NCBITaxon:phylum [Term] id: NCBITaxon:6072 name: Eumetazoa namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:33208 ! Metazoa property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:6073 name: Cnidaria namespace: ncbi_taxonomy synonym: "cnidarians" EXACT genbank_common_name [] synonym: "cnidarians" RELATED blast_name [] synonym: "Coelenterata" RELATED in_part [] synonym: "coelenterates" EXACT OMO:0003003 [] xref: GC_ID:1 is_a: NCBITaxon:6072 ! Eumetazoa property_value: has_rank NCBITaxon:phylum [Term] id: NCBITaxon:6157 name: Platyhelminthes namespace: ncbi_taxonomy synonym: "flatworm" EXACT OMO:0003003 [] synonym: "flatworms" EXACT genbank_common_name [] synonym: "flatworms" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:1206795 ! Lophotrochozoa disjoint_from: NCBITaxon:6340 ! Annelida property_value: has_rank NCBITaxon:phylum [Term] id: NCBITaxon:6231 name: Nematoda namespace: ncbi_taxonomy synonym: "Nemata" RELATED synonym [] synonym: "nematode" EXACT OMO:0003003 [] synonym: "nematodes" EXACT OMO:0003003 [] synonym: "nematodes" RELATED blast_name [] synonym: "roundworm" EXACT OMO:0003003 [] synonym: "roundworms" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:1206794 ! Ecdysozoa disjoint_from: NCBITaxon:88770 ! Panarthropoda property_value: has_rank NCBITaxon:phylum [Term] id: NCBITaxon:6236 name: Rhabditida namespace: ncbi_taxonomy alt_id: NCBITaxon:33251 alt_id: NCBITaxon:6308 synonym: "Strongylida" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:119089 ! Chromadorea property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:6237 name: Caenorhabditis namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:55885 ! Peloderinae property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:6239 name: Caenorhabditis elegans namespace: ncbi_taxonomy synonym: "Rhabditis elegans" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:6237 ! Caenorhabditis property_value: has_rank NCBITaxon:species [Term] id: NCBITaxon:6243 name: Rhabditidae namespace: ncbi_taxonomy alt_id: NCBITaxon:54603 xref: GC_ID:1 is_a: NCBITaxon:55879 ! Rhabditoidea property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:6340 name: Annelida namespace: ncbi_taxonomy synonym: "annelid worms" EXACT genbank_common_name [] synonym: "segmented worms" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:1206795 ! Lophotrochozoa property_value: has_rank NCBITaxon:phylum [Term] id: NCBITaxon:6341 name: Polychaeta namespace: ncbi_taxonomy synonym: "polychaetes" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:6340 ! Annelida property_value: has_rank NCBITaxon:class [Term] id: NCBITaxon:6362 name: Sabellida namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:105391 ! Canalipalpata property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:6656 name: Arthropoda namespace: ncbi_taxonomy synonym: "arthropods" EXACT genbank_common_name [] synonym: "arthropods" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:88770 ! Panarthropoda property_value: has_rank NCBITaxon:phylum [Term] id: NCBITaxon:6960 name: Hexapoda namespace: ncbi_taxonomy synonym: "Atelocerata" RELATED in_part [] synonym: "hexapods" RELATED blast_name [] synonym: "insects" EXACT genbank_common_name [] synonym: "Tracheata" RELATED in_part [] synonym: "Uniramia" RELATED in_part [] xref: GC_ID:1 is_a: NCBITaxon:197562 ! Pancrustacea property_value: has_rank NCBITaxon:subphylum [Term] id: NCBITaxon:7147 name: Diptera namespace: ncbi_taxonomy synonym: "flies" EXACT genbank_common_name [] synonym: "flies" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:33392 ! Endopterygota property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:716545 name: saccharomyceta namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:4890 ! Ascomycota property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:7203 name: Brachycera namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:7147 ! Diptera property_value: has_rank NCBITaxon:suborder [Term] id: NCBITaxon:7214 name: Drosophilidae namespace: ncbi_taxonomy synonym: "pomace flies" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:43746 ! Ephydroidea property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:7215 name: Drosophila namespace: ncbi_taxonomy alt_id: NCBITaxon:7326 synonym: "Drosophila" EXACT scientific_name [] synonym: "fruit flies" EXACT genbank_common_name [] synonym: "fruit fly" EXACT OMO:0003003 [] xref: GC_ID:1 is_a: NCBITaxon:46877 ! Drosophilini property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:7227 name: Drosophila melanogaster namespace: ncbi_taxonomy alt_id: NCBITaxon:2267365 synonym: "fruit fly" EXACT genbank_common_name [] synonym: "Sophophora melanogaster" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:32351 ! melanogaster subgroup property_value: has_rank NCBITaxon:species [Term] id: NCBITaxon:7496 name: Pterygota namespace: ncbi_taxonomy synonym: "Pterygota" EXACT scientific_name [] synonym: "winged insects" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:85512 ! Dicondylia property_value: has_rank NCBITaxon:subclass [Term] id: NCBITaxon:7711 name: Chordata namespace: ncbi_taxonomy synonym: "chordates" EXACT genbank_common_name [] synonym: "chordates" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:33511 ! Deuterostomia property_value: has_rank NCBITaxon:phylum [Term] id: NCBITaxon:7712 name: Tunicata namespace: ncbi_taxonomy synonym: "tunicates" EXACT genbank_common_name [] synonym: "tunicates" RELATED blast_name [] synonym: "Urochordata" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:7711 ! Chordata disjoint_from: NCBITaxon:89593 ! Craniata property_value: has_rank NCBITaxon:subphylum [Term] id: NCBITaxon:7742 name: Vertebrata namespace: ncbi_taxonomy synonym: "Vertebrata" EXACT scientific_name [] synonym: "vertebrates" EXACT genbank_common_name [] synonym: "vertebrates" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:89593 ! Craniata property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:7761 name: Myxiniformes namespace: ncbi_taxonomy synonym: "hagfishes" RELATED blast_name [] synonym: "Myxinoidea" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:117565 ! Myxini property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:7762 name: Myxinidae namespace: ncbi_taxonomy synonym: "hagfishes" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:7761 ! Myxiniformes property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:7776 name: Gnathostomata namespace: ncbi_taxonomy synonym: "Gnathostomata" EXACT scientific_name [] synonym: "jawed vertebrates" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:7742 ! Vertebrata property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:7777 name: Chondrichthyes namespace: ncbi_taxonomy synonym: "cartilaginous fishes" EXACT genbank_common_name [] synonym: "cartilaginous fishes" RELATED blast_name [] synonym: "fish" EXACT OMO:0003003 [] synonym: "fishes" EXACT OMO:0003003 [] xref: GC_ID:1 is_a: NCBITaxon:7776 ! Gnathostomata property_value: has_rank NCBITaxon:class [Term] id: NCBITaxon:78536 name: Euphyllophyta namespace: ncbi_taxonomy synonym: "euphyllophytes" EXACT equivalent_name [] xref: GC_ID:1 is_a: NCBITaxon:58023 ! Tracheophyta property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:7863 name: Holocephali namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:7777 ! Chondrichthyes property_value: has_rank NCBITaxon:subclass [Term] id: NCBITaxon:7864 name: Chimaeriformes namespace: ncbi_taxonomy synonym: "chimaeras" EXACT genbank_common_name [] synonym: "chimaeras" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:7863 ! Holocephali property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:7878 name: Dipnomorpha namespace: ncbi_taxonomy synonym: "Choanichthyes" RELATED in_part [] synonym: "Dipneusti" RELATED synonym [] synonym: "dipnoans" EXACT OMO:0003003 [] synonym: "Dipnoi" RELATED synonym [] synonym: "fish" EXACT OMO:0003003 [] synonym: "fishes" EXACT OMO:0003003 [] synonym: "lungfishes" EXACT genbank_common_name [] synonym: "lungfishes" RELATED blast_name [] synonym: "Osteichthyes" RELATED in_part [] xref: GC_ID:1 is_a: NCBITaxon:1338369 ! Dipnotetrapodomorpha property_value: has_rank NCBITaxon:subclass [Term] id: NCBITaxon:7898 name: Actinopterygii namespace: ncbi_taxonomy synonym: "Actinopterygi" RELATED synonym [] synonym: "bony fishes" RELATED blast_name [] synonym: "fish" EXACT OMO:0003003 [] synonym: "fishes" EXACT OMO:0003003 [] synonym: "Osteichthyes" RELATED in_part [] synonym: "ray-finned fishes" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:117571 ! Euteleostomi disjoint_from: NCBITaxon:8287 ! Sarcopterygii property_value: has_rank NCBITaxon:superclass [Term] id: NCBITaxon:7899 name: Acipenseriformes namespace: ncbi_taxonomy synonym: "sturgeons and paddlefish" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:32440 ! Chondrostei property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:7900 name: Acipenseridae namespace: ncbi_taxonomy synonym: "sturgeons" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:186622 ! Acipenseroidei property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:7901 name: Acipenser namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:124130 ! Acipenserini property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:7952 name: Cypriniformes namespace: ncbi_taxonomy synonym: "carps and others" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:186627 ! Cypriniphysae property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:7954 name: Danio namespace: ncbi_taxonomy alt_id: NCBITaxon:46777 alt_id: NCBITaxon:487617 synonym: "Brachydanio" RELATED synonym [] synonym: "Celestichthys" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:2743711 ! Danioninae property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:7955 name: Danio rerio namespace: ncbi_taxonomy alt_id: NCBITaxon:27702 alt_id: NCBITaxon:37966 synonym: "Brachydanio rerio" RELATED synonym [] synonym: "Brachydanio rerio frankei" RELATED synonym [] synonym: "Cyprinus rerio" RELATED synonym [] synonym: "Danio frankei" RELATED synonym [] synonym: "Danio rerio frankei" RELATED synonym [] synonym: "leopard danio" EXACT OMO:0003003 [] synonym: "zebra danio" EXACT OMO:0003003 [] synonym: "zebra fish" EXACT OMO:0003003 [] synonym: "zebrafish" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:7954 ! Danio property_value: has_rank NCBITaxon:species [Term] id: NCBITaxon:8287 name: Sarcopterygii namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:117571 ! Euteleostomi property_value: has_rank NCBITaxon:superclass [Term] id: NCBITaxon:8292 name: Amphibia namespace: ncbi_taxonomy synonym: "amphibians" EXACT genbank_common_name [] synonym: "amphibians" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:32523 ! Tetrapoda property_value: has_rank NCBITaxon:class [Term] id: NCBITaxon:8342 name: Anura namespace: ncbi_taxonomy synonym: "anurans" EXACT OMO:0003003 [] synonym: "frogs" EXACT OMO:0003003 [] synonym: "frogs & toads" RELATED blast_name [] synonym: "frogs and toads" EXACT genbank_common_name [] synonym: "Salientia" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:41666 ! Batrachia property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:8352 name: Pipidae namespace: ncbi_taxonomy synonym: "pipid frogs" EXACT OMO:0003003 [] synonym: "tongueless frogs" EXACT genbank_common_name [] xref: GC_ID:1 xref: PMID:2385174 is_a: NCBITaxon:30319 ! Pipoidea property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:8353 name: Xenopus namespace: ncbi_taxonomy synonym: "Xenopus" EXACT scientific_name [] xref: GC_ID:1 xref: PMID:2385174 is_a: NCBITaxon:8360 ! Xenopodinae property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:8355 name: Xenopus laevis namespace: ncbi_taxonomy synonym: "African clawed frog" EXACT genbank_common_name [] synonym: "Bufo laevis" RELATED synonym [] synonym: "clawed frog" EXACT OMO:0003003 [] synonym: "common platanna" EXACT OMO:0003003 [] synonym: "platanna" EXACT OMO:0003003 [] xref: GC_ID:1 is_a: NCBITaxon:262014 ! Xenopus property_value: has_rank NCBITaxon:species [Term] id: NCBITaxon:8360 name: Xenopodinae namespace: ncbi_taxonomy synonym: "Siluraninae" RELATED synonym [] xref: GC_ID:1 xref: PMID:2385174 is_a: NCBITaxon:8352 ! Pipidae property_value: has_rank NCBITaxon:subfamily [Term] id: NCBITaxon:8457 name: Sauropsida namespace: ncbi_taxonomy synonym: "sauropsids" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:32524 ! Amniota property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:8492 name: Archosauria namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:1329799 ! Archelosauria property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:85512 name: Dicondylia namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:50557 ! Insecta property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:862507 name: Mus namespace: ncbi_taxonomy synonym: "Mus" EXACT scientific_name [] xref: GC_ID:1 is_a: NCBITaxon:10088 ! Mus property_value: has_rank NCBITaxon:subgenus [Term] id: NCBITaxon:8782 name: Aves namespace: ncbi_taxonomy synonym: "avian" RELATED synonym [] synonym: "birds" EXACT genbank_common_name [] synonym: "birds" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:436492 ! Coelurosauria property_value: has_rank NCBITaxon:class [Term] id: NCBITaxon:8783 name: Palaeognathae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:8782 ! Aves disjoint_from: NCBITaxon:8825 ! Neognathae property_value: has_rank NCBITaxon:superorder [Term] id: NCBITaxon:8798 name: Struthioniformes namespace: ncbi_taxonomy synonym: "ostriches" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:8783 ! Palaeognathae property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:8799 name: Struthionidae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:8798 ! Struthioniformes property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:8800 name: Struthio namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:8799 ! Struthionidae property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:8801 name: Struthio camelus namespace: ncbi_taxonomy synonym: "African ostrich" EXACT genbank_common_name [] synonym: "ostrich" EXACT OMO:0003003 [] synonym: "Struthio camelus domesticus" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:8800 ! Struthio property_value: has_rank NCBITaxon:species [Term] id: NCBITaxon:8825 name: Neognathae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:8782 ! Aves property_value: has_rank NCBITaxon:infraclass [Term] id: NCBITaxon:88770 name: Panarthropoda namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:1206794 ! Ecdysozoa property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:8929 name: Columbiformes namespace: ncbi_taxonomy synonym: "pigeons and others" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:8825 ! Neognathae property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:8930 name: Columbidae namespace: ncbi_taxonomy synonym: "pigeons" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:8929 ! Columbiformes property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:89593 name: Craniata namespace: ncbi_taxonomy synonym: "Craniata" EXACT scientific_name [] xref: GC_ID:1 is_a: NCBITaxon:7711 ! Chordata property_value: has_rank NCBITaxon:subphylum [Term] id: NCBITaxon:9254 name: Prototheria namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:40674 ! Mammalia property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:9255 name: Monotremata namespace: ncbi_taxonomy synonym: "egg-laying mammals" EXACT genbank_common_name [] synonym: "monotremes" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:9254 ! Prototheria property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:9259 name: Tachyglossidae namespace: ncbi_taxonomy synonym: "echidnas" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:9255 ! Monotremata property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:9347 name: Eutheria namespace: ncbi_taxonomy synonym: "eutherian mammals" EXACT OMO:0003003 [] synonym: "placental mammals" EXACT OMO:0003003 [] synonym: "Placentalia" RELATED synonym [] synonym: "placentals" EXACT genbank_common_name [] synonym: "placentals" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:32525 ! Theria property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:9443 name: Primates namespace: ncbi_taxonomy synonym: "Primata" RELATED synonym [] synonym: "primate" EXACT equivalent_name [] synonym: "primates" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:314146 ! Euarchontoglires property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:9526 name: Catarrhini namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:314293 ! Simiiformes property_value: has_rank NCBITaxon:parvorder [Term] id: NCBITaxon:9604 name: Hominidae namespace: ncbi_taxonomy synonym: "great apes" EXACT genbank_common_name [] synonym: "Pongidae" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:314295 ! Hominoidea property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:9605 name: Homo namespace: ncbi_taxonomy synonym: "humans" EXACT OMO:0003003 [] xref: GC_ID:1 is_a: NCBITaxon:207598 ! Homininae property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:9606 name: Homo sapiens namespace: ncbi_taxonomy synonym: "human" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:9605 ! Homo property_value: has_rank NCBITaxon:species [Term] id: NCBITaxon:9989 name: Rodentia namespace: ncbi_taxonomy synonym: "rodent" EXACT genbank_common_name [] synonym: "rodents" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:314147 ! Glires property_value: has_rank NCBITaxon:order [Term] id: OBI:0000011 name: planned process def: "A process that realizes a plan which is the concretization of a plan specification." [] is_a: BFO:0000015 ! process property_value: IAO:0000111 "planned process" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/obi.owl [Term] id: OBI:0100026 name: organism namespace: obi comment: Category=external. is_a: BFO:0000030 ! object [Term] id: PATO:0000001 name: quality namespace: quality alt_id: PATO:0000072 def: "A dependent entity that inheres in a bearer by virtue of how the bearer is related to other entities" [PATOC:GVG] is_a: BFO:0000020 ! specifically dependent continuant [Term] id: PATO:0000025 name: composition namespace: quality alt_id: PATO:0002015 def: "A single physical entity inhering in an bearer by virtue of the bearer's quantities or relative ratios of subparts." [PATOC:GVG] comment: For example calcium composition (which may inhere in bone), haemoglobin composition (which may inhere in blood). subset: attribute_slim subset: scalar_slim synonym: "composed of" EXACT [] synonym: "compositionality" EXACT [] synonym: "content" EXACT [] synonym: "structure, composition" EXACT [] is_a: PATO:0000141 ! structure [Term] id: PATO:0000039 name: direction namespace: quality def: "A physical quality inhering in a bearer by virtue of the bearer's orientation in space." [] def: "A physical quality inhering in a bearer by virtue of the bearer's orientation in space." [thesaurus.maths:thesaurus.maths] comment: TODO: consider merging with angular placement. subset: attribute_slim is_a: PATO:0001018 ! physical quality [Term] id: PATO:0000040 name: distance namespace: quality def: "A quality that is the extent of space between two entities." [PATOC:GVG] subset: attribute_slim subset: relational_slim subset: scalar_slim is_a: PATO:0001018 ! physical quality [Term] id: PATO:0000051 name: morphology namespace: quality def: "A quality of a single physical entity inhering in the bearer by virtue of the bearer's size or shape or structure." [PATOC:GVG] subset: attribute_slim is_a: PATO:0001241 ! physical object quality property_value: IAO:0000111 "morphology" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/pato.owl [Term] id: PATO:0000052 name: shape namespace: quality alt_id: PATO:0001647 def: "A morphological quality inhering in a bearer by virtue of the bearer's ratios of distances between its features (points, edges, surfaces and also holes etc)." [PATOC:GVG] comment: Shapes are invariant on size transformations. Shapes can be subdivided into 2D and 3D shapes, We can also make a distinction between shapes of complete self-connected objects, and shapes of parts of objects. subset: attribute_slim synonym: "relational shape quality" EXACT [] is_a: PATO:0000051 ! morphology [Term] id: PATO:0000060 name: spatial pattern namespace: quality alt_id: PATO:0000132 alt_id: PATO:0001565 def: "A spatial quality inhering in a bearer by virtue of the bearer's exhibiting repetition of placement of its parts." [PATOC:GVG] subset: attribute_slim subset: hpo_slim synonym: "distribution" EXACT [] synonym: "pattern" RELATED [] is_a: PATO:0000051 ! morphology [Term] id: PATO:0000068 name: qualitative namespace: quality def: "A quality of an entity that is descriptive or observational, typically not represented numerically." [https://libguides.macalester.edu/c.php?g=527786&p=3608639, https://www.ncbi.nlm.nih.gov/books/NBK470395/] comment: TODO: define this or obsolete it and move children somewhere else. is_a: PATO:0000001 ! quality [Term] id: PATO:0000069 name: deviation (from_normal) namespace: quality def: "A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average." [PATOC:GVG] subset: attribute_slim is_a: PATO:0000068 ! qualitative [Term] id: PATO:0000070 name: amount namespace: quality alt_id: PATO:0000053 alt_id: PATO:0000071 alt_id: PATO:0001169 alt_id: PATO:0001226 def: "The number of entities of this type that are part of the whole organism." [PATOC:GVG] comment: This term was originally named "presence". It has been renamed to reduce ambiguity. Consider annotating with the reciprocal relation,PATO:0001555, has_number_of. For example, rather than E=fin ray Q=count in organism C=10, say E=organism Q=has number of E2= fin ray C=10. subset: attribute_slim synonym: "count in organism" RELATED [] synonym: "number" RELATED [] synonym: "presence" RELATED [] synonym: "presence or absence in organism" EXACT [] synonym: "quantitative" EXACT [] is_a: PATO:0103000 ! quantitative relationship: RO:0015012 PATO:0001555 ! has number of [Term] id: PATO:0000117 name: size namespace: quality def: "A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude." [WordNet:WordNet] subset: attribute_slim subset: scalar_slim is_a: PATO:0000051 ! morphology [Term] id: PATO:0000122 name: length namespace: quality def: "A 1-D extent quality which is equal to the distance between two points." [PATOC:GVG] comment: Length often refers to the longer or longest dimension of an object, however, this is not always true. See https://github.com/pato-ontology/pato/issues/337 for full discussion. subset: attribute_slim subset: mpath_slim subset: scalar_slim is_a: PATO:0001708 ! 1-D extent property_value: IAO:0000111 "length" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/pato.owl property_value: seeAlso "https://github.com/pato-ontology/pato/issues/337" xsd:string [Term] id: PATO:0000136 name: closure namespace: quality def: "A morphological quality pertaining to the degree to which an object contains an opening, aperture, orifice or vent." [PATOC:CJM, PATOC:GVG] subset: attribute_slim is_a: PATO:0000051 ! morphology [Term] id: PATO:0000141 name: structure namespace: quality alt_id: PATO:0001452 def: "A morphology quality inhering in a bearer by virtue of the bearer's relative position, shape, arrangements and connectivity of an organism's various parts; the pattern underlying its form." [PATOC:GVG] subset: attribute_slim synonym: "conformation" BROAD [VT:1000738] synonym: "relational structural quality" EXACT [] is_a: PATO:0000051 ! morphology [Term] id: PATO:0000150 name: texture namespace: quality def: "A morphologic quality inhering in a bearer by virtue of the bearer's relative size, organization and distribution of its surface elements or the representation or invention of the appearance of its surface; visual and tactile surface characteristics." [PATOC:GVG] subset: attribute_slim is_a: PATO:0000051 ! morphology [Term] id: PATO:0000261 name: maturity namespace: quality def: "A quality of a single physical entity which is held by a bearer when the latter exhibits a state of growth, differentiation, or development." [Merriam-Webster:Merriam-Webster] subset: attribute_slim is_a: PATO:0001995 ! organismal quality [Term] id: PATO:0000365 name: down namespace: quality def: "A directional quality inhering in a bearer by virtue of the bearer's direction from a higher to a lower point." [] def: "A directional quality inhering in a bearer by virtue of the bearer's direction from a higher to a lower point." [PATOC:GVG] subset: value_slim is_a: PATO:0000039 ! direction property_value: RO:0002604 PATO:0000370 [Term] id: PATO:0000374 name: increased distance namespace: quality def: "A distance which is greater relative to the normal or average." [PATOC:GVG] subset: relational_slim subset: value_slim synonym: "long distance" RELATED [] is_a: PATO:0000040 ! distance is_a: PATO:0002305 ! increased object quality intersection_of: PATO:0000040 ! distance intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal property_value: RO:0002604 PATO:0000375 [Term] id: PATO:0000375 name: decreased distance namespace: quality def: "A distance which is lesser relative to the normal or average." [PATOC:GVG] subset: relational_slim subset: value_slim synonym: "short distance" RELATED [] is_a: PATO:0000040 ! distance is_a: PATO:0002303 ! decreased object quality intersection_of: PATO:0000040 ! distance intersection_of: RO:0015008 PATO:0000461 ! decreased in magnitude relative to normal property_value: RO:0002604 PATO:0000374 [Term] id: PATO:0000402 name: branched namespace: quality def: "A branchiness quality inhering in a bearer by virtue of the bearer's having branches." [WordNet:WordNet] subset: cell_quality subset: mpath_slim subset: value_slim synonym: "ramified" EXACT [] synonym: "ramiform" EXACT [] is_a: PATO:0002009 ! branchiness property_value: RO:0002604 PATO:0000414 [Term] id: PATO:0000404 name: coiled namespace: quality alt_id: PATO:0001363 def: "A shape quality inhering in a bearer by virtue of the bearer's being curled or wound (especially in concentric rings or spirals)." [WordNet:WordNet] subset: cell_quality subset: mpath_slim subset: value_slim synonym: "helical" RELATED [] synonym: "helicoid" RELATED [] synonym: "helicoidal" RELATED [] synonym: "helix-shaped" RELATED [] synonym: "spiral" EXACT [] is_a: PATO:0001794 ! coiling property_value: RO:0002604 PATO:0000415 [Term] id: PATO:0000407 name: flat namespace: quality def: "A quality inhering in a bearer by virtue of the bearer's having a horizontal surface without a slope, tilt, or curvature." [web:http\://www.merriam-webster.com/] subset: cell_quality subset: mpath_slim subset: value_slim synonym: "plate-like" RELATED [] is_a: PATO:0002254 ! flattened [Term] id: PATO:0000411 name: circular namespace: quality def: "A shape quality inhering in a bearer by virtue of the bearer's being such that every part of the surface or the circumference is equidistant from the center." [thefreedictionary.com:thefreedictionary.com] subset: cell_quality subset: mpath_slim subset: value_slim synonym: "round" RELATED [] synonym: "rounded" RELATED [] is_a: PATO:0000947 ! elliptic [Term] id: PATO:0000461 name: normal namespace: quality def: "A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average." [PATOC:GVG] subset: abnormal_slim subset: mpath_slim subset: value_slim synonym: "average" RELATED [] is_a: PATO:0000068 ! qualitative property_value: RO:0002604 PATO:0000460 [Term] id: PATO:0000467 name: present namespace: quality def: "A quality inhering in a bearer by virtue of the bearer's existence." [PATOC:GVG] subset: absent_slim subset: value_slim synonym: "present in organism" RELATED [] is_a: PATO:0000070 ! amount property_value: RO:0002604 PATO:0000462 [Term] id: PATO:0000470 name: increased amount namespace: quality alt_id: PATO:0000420 alt_id: PATO:0000650 def: "An amount which is relatively high." [PATOC:GVG] subset: value_slim synonym: "accessory" RELATED [] synonym: "increased" RELATED [] synonym: "increased number" EXACT [] synonym: "present in greater numbers in organism" EXACT [] synonym: "supernumerary" EXACT [] is_a: PATO:0000467 ! present is_a: PATO:0002300 ! increased quality intersection_of: PATO:0000070 ! amount intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal property_value: RO:0002604 PATO:0001997 [Term] id: PATO:0000573 name: increased length namespace: quality def: "A length quality which is relatively large." [PATOC:GVG] subset: value_slim synonym: "long" EXACT [] is_a: PATO:0000122 ! length is_a: PATO:0000586 ! increased size intersection_of: PATO:0000122 ! length intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal property_value: RO:0002604 PATO:0000574 [Term] id: PATO:0000574 name: decreased length namespace: quality def: "A length quality which is relatively small." [PATOC:GVG] subset: value_slim synonym: "short" EXACT [] synonym: "shortened" RELATED [] synonym: "stubby" RELATED [] is_a: PATO:0000122 ! length is_a: PATO:0000587 ! decreased size intersection_of: PATO:0000122 ! length intersection_of: RO:0015008 PATO:0000461 ! decreased in magnitude relative to normal property_value: RO:0002604 PATO:0000573 [Term] id: PATO:0000586 name: increased size namespace: quality alt_id: PATO:0001202 def: "A size quality which is relatively high." [PATOC:GVG] subset: value_slim synonym: "big" RELATED [] synonym: "enlarged" RELATED [] synonym: "expanded" RELATED [] synonym: "great" RELATED [] synonym: "large" RELATED [] is_a: PATO:0000117 ! size is_a: PATO:0002305 ! increased object quality intersection_of: PATO:0000117 ! size intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal property_value: RO:0002604 PATO:0000587 [Term] id: PATO:0000587 name: decreased size namespace: quality def: "A size quality which is relatively low." [PATOC:GVG] subset: value_slim synonym: "hypoplasia" NARROW [] synonym: "reduced" RELATED [] synonym: "small" RELATED [] synonym: "tiny" RELATED [] synonym: "underdeveloped" NARROW [] is_a: PATO:0000117 ! size is_a: PATO:0002303 ! decreased object quality intersection_of: PATO:0000117 ! size intersection_of: RO:0015008 PATO:0000461 ! decreased in magnitude relative to normal property_value: RO:0002604 PATO:0000586 [Term] id: PATO:0000591 name: increased thickness namespace: quality def: "A thickness which is relatively high." [PATOC:GVG] subset: mpath_slim subset: value_slim synonym: "high thickness" EXACT [] synonym: "stout" EXACT [] synonym: "thick" RELATED [] synonym: "thickened" EXACT [] is_a: PATO:0000586 ! increased size is_a: PATO:0000915 ! thickness intersection_of: PATO:0000915 ! thickness intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal property_value: RO:0002604 PATO:0000592 [Term] id: PATO:0000592 name: decreased thickness namespace: quality def: "A thickness which is relatively low." [PATOC:GVG] subset: mpath_slim subset: value_slim synonym: "low thickness" EXACT [] synonym: "slender" RELATED [] synonym: "thin" RELATED [] is_a: PATO:0000587 ! decreased size is_a: PATO:0000915 ! thickness intersection_of: PATO:0000915 ! thickness intersection_of: RO:0015008 PATO:0000461 ! decreased in magnitude relative to normal property_value: RO:0002604 PATO:0000591 [Term] id: PATO:0000599 name: decreased width namespace: quality def: "A width which is relatively small." [PATOC:GVG] subset: value_slim synonym: "narrow" RELATED [] is_a: PATO:0000587 ! decreased size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: RO:0015008 PATO:0000461 ! decreased in magnitude relative to normal property_value: RO:0002604 PATO:0000600 [Term] id: PATO:0000600 name: increased width namespace: quality def: "A width which is relatively large." [PATOC:GVG] subset: value_slim synonym: "broad" RELATED [] synonym: "wide" RELATED [] synonym: "wide/broad" RELATED [] is_a: PATO:0000586 ! increased size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal property_value: RO:0002604 PATO:0000599 [Term] id: PATO:0000608 name: closed namespace: quality def: "A morphological quality inhering in a bearer by virtue of the bearer's affording blocked passage or view." [answers.com:answers.com] subset: value_slim synonym: "blocked" RELATED [] is_a: PATO:0000136 ! closure property_value: RO:0002604 PATO:0000610 [Term] id: PATO:0000915 name: thickness namespace: quality def: "A 1-D extent quality which is equal to the dimension through an object as opposed to its length or width." [WordNet:WordNet] comment: Thickness often refers to the smallest 1-D extent compared to the other two orthogonal dimensions, however, this is not always true. See https://github.com/pato-ontology/pato/issues/337 for full discussion. subset: attribute_slim subset: scalar_slim is_a: PATO:0001708 ! 1-D extent property_value: seeAlso "https://github.com/pato-ontology/pato/issues/337" xsd:string [Term] id: PATO:0000921 name: width namespace: quality def: "A 1-D extent quality which is equal to the distance from one side of an object to another side which is opposite." [PATOC:GVG] comment: Width often refers to the dimension that is greater than the extent in only one of the other two orthogonal dimensions, however, this is not always true. See https://github.com/pato-ontology/pato/issues/337 for full discussion. subset: attribute_slim subset: scalar_slim synonym: "breadth" RELATED [] is_a: PATO:0001708 ! 1-D extent property_value: seeAlso "https://github.com/pato-ontology/pato/issues/337" xsd:string [Term] id: PATO:0000944 name: sharpness namespace: quality def: "A shape quality inhering in a bearer by virtue of the bearer's having a sharp or tapered end or point." [PATOC:GVG] subset: attribute_slim subset: cell_quality synonym: "apiculate" EXACT [] is_a: PATO:0000052 ! shape [Term] id: PATO:0000947 name: elliptic namespace: quality def: "A spheroid quality inhering in a bearer by virtue of the bearer's being oval with two axes of symmetry, as produced by a conical section." [PATOC:GVG] subset: cell_quality subset: mpath_slim subset: value_slim synonym: "ellipse-shaped" EXACT [] synonym: "ellipsoid" EXACT [] synonym: "elliptical" EXACT [] synonym: "oval" RELATED [] synonym: "ovoid" RELATED [] is_a: PATO:0002318 ! superelliptic [Term] id: PATO:0000957 name: opacity namespace: quality def: "An optical quality which obtains by virtue of the ability of the bearer to absorb visible light." [PATOC:GVG] subset: attribute_slim is_a: PATO:0001300 ! optical quality [Term] id: PATO:0000963 name: opaque namespace: quality def: "A optical quality inhering in a bearer by virtue of the bearer's not being clear; not transmitting or reflecting light or radiant energy." [PATOC:GVG] subset: mpath_slim subset: value_slim synonym: "clouding" RELATED [] synonym: "cloudy" RELATED [] synonym: "non-transparent" EXACT [] is_a: PATO:0000957 ! opacity property_value: RO:0002604 PATO:0000964 [Term] id: PATO:0000964 name: transparent namespace: quality def: "A optical quality inhering in a bearer by virtue of the bearer's lacking opacity." [PATOC:GVG] subset: mpath_slim subset: value_slim synonym: "clear" EXACT [] synonym: "hyaline" EXACT [] is_a: PATO:0000957 ! opacity property_value: RO:0002604 PATO:0000963 [Term] id: PATO:0000965 name: symmetry namespace: quality def: "A pattern quality of inhering in a bearer by virtue of the correspondence in size, shape, and relative position of the bearer's parts on opposite sides of a dividing line or median plane or about a center or axis." [PATOC:GVG] subset: attribute_slim is_a: PATO:0000060 ! spatial pattern [Term] id: PATO:0000973 name: porosity namespace: quality def: "A structure quality inhering in a bearer by virtue of the bearer's disposition to admit the passage of gas or liquid through pores or interstices." [PATOC:GVG] subset: attribute_slim subset: disposition_slim subset: scalar_slim is_a: PATO:0000141 ! structure [Term] id: PATO:0000984 name: porous namespace: quality def: "A porosity quality inhering in a bearer by virtue of the bearer's being capable of admitting the passage of gas or liquid through pores or interstices." [PATOC:GVG] subset: disposition_slim subset: value_slim is_a: PATO:0000973 ! porosity property_value: RO:0002604 PATO:0000985 [Term] id: PATO:0000992 name: viscosity namespace: quality def: "A physical quality of a fluid inhering in a bearer by virtue of the bearer's disposition to internal resistance to flow." [PATOC:GVG] subset: attribute_slim subset: disposition_slim is_a: PATO:0001548 ! quality of a liquid [Term] id: PATO:0000998 name: viscous namespace: quality def: "A viscosity quality inhering in a bearer by virtue of the bearer's having viscosity." [PATOC:GVG] subset: disposition_slim subset: mpath_slim subset: value_slim is_a: PATO:0000992 ! viscosity [Term] id: PATO:0001018 name: physical quality namespace: quality alt_id: PATO:0002079 def: "A quality of a physical entity that exists through action of continuants at the physical level of organisation in relation to other entities." [PATOC:GVG] subset: attribute_slim synonym: "relational physical quality" EXACT [] xref: Wikipedia:Physical_property is_a: PATO:0001241 ! physical object quality [Term] id: PATO:0001031 name: elasticity namespace: quality def: "A physical quality inhering in a bearer by virtue of the bearer's disposition to recover its size and shape after deformation in any way." [merriam-webster:merriam-webster] subset: attribute_slim subset: disposition_slim subset: scalar_slim is_a: PATO:0001018 ! physical quality [Term] id: PATO:0001154 name: elongated namespace: quality def: "A quality inhering in a bearer by virtue of the bearer's length being notably higher than its width." [WordNet:WordNet] subset: value_slim is_a: PATO:0000052 ! shape property_value: RO:0002604 PATO:0002364 [Term] id: PATO:0001171 name: elastic namespace: quality def: "An elasticity quality inhering in a bearer by virtue of the bearer's ability to recover its size and shape after deformation in any way." [merriam-webster:merriam-webster] subset: disposition_slim subset: mpath_slim subset: value_slim is_a: PATO:0001031 ! elasticity property_value: RO:0002604 PATO:0001172 [Term] id: PATO:0001185 name: larval namespace: quality def: "A maturity quality inhering in a bearer by virtue of the bearer's indirect development, undergoing metamorphosis." [Wikipedia:http\://en.wikipedia.org/wiki/Larval] subset: value_slim is_a: PATO:0000261 ! maturity [Term] id: PATO:0001190 name: juvenile namespace: quality def: "A maturity quality inhering in a bearer by virtue the bearer's being not fully grown or developed." [thefreedictionary.com:thefreedictionary.com] subset: mpath_slim subset: value_slim is_a: PATO:0000261 ! maturity [Term] id: PATO:0001199 name: linear namespace: quality def: "A shape quality inhering in a bearer by virtue of the bearer's being narrow, with the two opposite margins parallel." [ISBN:0881923214] subset: cell_quality subset: mpath_slim subset: value_slim is_a: PATO:0000052 ! shape [Term] id: PATO:0001241 name: physical object quality namespace: quality alt_id: PATO:0001237 alt_id: PATO:0001238 def: "A quality which inheres in a continuant." [PATOC:GVG] comment: Relational qualities are qualities that hold between multiple entities. Normal (monadic) qualities such as the shape of a eyeball exist purely as a quality of that eyeball. A relational quality such as sensitivity to light is a quality of that eyeball (and connecting nervous system) as it relates to incoming light waves/particles. synonym: "monadic quality of a continuant" EXACT [] synonym: "monadic quality of an object" NARROW [] synonym: "monadic quality of continuant" NARROW [] synonym: "multiply inhering quality of a physical entity" EXACT [] synonym: "quality of a continuant" EXACT [] synonym: "quality of a single physical entity" EXACT [] synonym: "quality of an object" EXACT [] synonym: "quality of continuant" EXACT [] xref: snap:Quality is_a: BFO:0000019 ! quality is_a: PATO:0000001 ! quality property_value: IAO:0000111 "physical object quality" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/pato.owl [Term] id: PATO:0001300 name: optical quality namespace: quality def: "An EM radiation quality in which the EM radiation is within the fiat range of the spectrum visible deemed to be light." [PATOC:GVG] subset: attribute_slim is_a: PATO:0070060 ! quality of interaction of a substance with electromagnetic radiation [Term] id: PATO:0001355 name: convex namespace: quality def: "A shape quality that obtains by virtue of the bearer having inward facing edges; having a surface or boundary that curves or bulges outward, as the exterior of a sphere." [PATOC:GVG] subset: cell_quality subset: value_slim is_a: PATO:0002005 ! concavity property_value: RO:0002604 PATO:0001857 [Term] id: PATO:0001369 name: raised namespace: quality def: "A shape quality inhering in a colony by virtue of the bearer's appearing above the medium surface with terraced edges." [PATOC:GVG] subset: mpath_slim subset: value_slim is_a: PATO:0000052 ! shape [Term] id: PATO:0001374 name: ploidy namespace: quality def: "A cellular quality inhering in a bearer by virtue of the bearer's number of homologous sets of chromosomes in the nucleus or primary chromosome-containing compartment of the cell, each set essentially coding for all the biological traits of the organism." [Wikipedia:http\://en.wikipedia.org/wiki/Ploidy] subset: attribute_slim is_a: PATO:0001396 ! cellular quality [Term] id: PATO:0001375 name: haploid namespace: quality def: "A ploidy quality inhering in a bearer by virtue of the bearer's containing a single set of homologous chromosomes." [Wikipedia:http\://en.wikipedia.org/wiki/Haploid] subset: cell_quality subset: value_slim is_a: PATO:0001393 ! euploid [Term] id: PATO:0001377 name: polyploid namespace: quality def: "A ploidy quality inhering in a bearer by virtue of the bearer's containing more than two homologous sets of chromosomes." [Wikipedia:http\://en.wikipedia.org/wiki/Polyploid] subset: cell_quality subset: value_slim is_a: PATO:0001393 ! euploid [Term] id: PATO:0001393 name: euploid namespace: quality def: "A ploidy quality inhering in a bearer by virtue of the bearer's containing an integral multiple of the monoploid number, possibly excluding the sex-determining chromosomes." [Wikipedia:http\://en.wikipedia.org/wiki/Euploid] subset: cell_quality subset: value_slim is_a: PATO:0001374 ! ploidy [Term] id: PATO:0001394 name: diploid namespace: quality def: "A ploidy quality inhering in a bearer by virtue of the bearer's having two copies (homologs) of each chromosome, usually one from the mother and one from the father." [Wikipedia:http\://en.wikipedia.org/wiki/Diploid] comment: The exact number may be one or two different from the 2n number and still be classified as diploidy (although with aneuploidy). Nearly all mammals are diploid organisms, although all individuals have some small fraction of cells that are polyploidy. subset: cell_quality subset: value_slim is_a: PATO:0001393 ! euploid [Term] id: PATO:0001396 name: cellular quality namespace: quality def: "A monadic quality of continuant that exists at the cellular level of organisation." [PATOC:GVG] is_a: PATO:0070044 ! anatomical structure quality [Term] id: PATO:0001397 name: cellular potency namespace: quality def: "A cellular quality that arises by virtue of whether the bearer's disposition to differentiate into one or more mature cell types." [PATOC:GVG] subset: attribute_slim subset: disposition_slim is_a: PATO:0001396 ! cellular quality [Term] id: PATO:0001400 name: unipotent namespace: quality def: "A cellular potency that is the capacity to produce only one differentiated cell type." [Wikipedia:http\://en.wikipedia.org/wiki/Unipotent] comment: Unipotent cells have the quality of self-renewal which distinguishes them from non-stem cells. subset: cell_quality subset: disposition_slim subset: value_slim is_a: PATO:0001397 ! cellular potency [Term] id: PATO:0001401 name: oligopotent namespace: quality def: "A cellular potency that is the capacity to form multiple differentiated cell types of a specific lineage and lack self renewing capacity." [PATOC:MAH] comment: Less potent than multipotent, often thought of as precursor or progenitor cell status. subset: cell_quality subset: disposition_slim subset: value_slim is_a: PATO:0001397 ! cellular potency [Term] id: PATO:0001402 name: multipotent namespace: quality def: "A cellular potency that is the capacity to form multiple differentiated cell types." [Wikipedia:http\://en.wikipedia.org/wiki/Multipotent] subset: cell_quality subset: disposition_slim subset: value_slim is_a: PATO:0001397 ! cellular potency [Term] id: PATO:0001404 name: nucleate quality namespace: quality def: "A cellular quality inhering in a bearer by virtue of bearer's number of nuclei." [PATOC:GVG] subset: attribute_slim is_a: PATO:0001396 ! cellular quality [Term] id: PATO:0001405 name: anucleate namespace: quality def: "A nucleate quality inhering in a bearer by virtue of the bearer's having no nucleus." [Biology-online:Biology-online] subset: cell_quality subset: mpath_slim subset: value_slim is_a: PATO:0001404 ! nucleate quality [Term] id: PATO:0001406 name: binucleate namespace: quality def: "A nucleate quality inhering in a bearer by virtue of the bearer's having two nuclei." [Biology-online:Biology-online] subset: cell_quality subset: mpath_slim subset: value_slim is_a: PATO:0001908 ! multinucleate [Term] id: PATO:0001407 name: mononucleate namespace: quality def: "A nucleate quality inhering in a bearer by virtue of the bearer's having one nucleus." [Biology-online:Biology-online] subset: cell_quality subset: mpath_slim subset: value_slim is_a: PATO:0002505 ! nucleated [Term] id: PATO:0001408 name: ciliatedness namespace: quality def: "A cellular quality inhering in a bearer by virtue of the bearer's having thin, tail-like projections extending outwards from the cell body." [Wikipedia:http\://en.wikipedia.org/wiki/Ciliated] subset: cell_quality subset: value_slim is_a: PATO:0001396 ! cellular quality [Term] id: PATO:0001410 name: striated namespace: quality def: "A shape quality inhering in a bearer by virtue of the bearer's being marked by narrow lines or grooves, usually parallel." [Biology-online:Biology-online] subset: cell_quality subset: mpath_slim subset: value_slim is_a: PATO:0000052 ! shape [Term] id: PATO:0001419 name: sharp namespace: quality def: "A shape quality inhering in a bearer by virtue of the bearer's terminating in a point or edge." [PATOC:GVG] subset: cell_quality subset: value_slim is_a: PATO:0000944 ! sharpness [Term] id: PATO:0001500 name: tapered namespace: quality def: "A shape quality inhering in a bearer by virtue of the bearer's being gradually narrower or thinner toward one end." [WordNet:WordNet] subset: cell_quality subset: value_slim synonym: "taper" EXACT [] is_a: PATO:0001419 ! sharp [Term] id: PATO:0001501 name: immature namespace: quality def: "A quality inhering in a bearer by virtue of the bearer's lacking complete growth, differentiation, or development." [Merriam-Webster:Merriam-Webster] subset: value_slim synonym: "underdeveloped" RELATED [] is_a: PATO:0000261 ! maturity property_value: RO:0002604 PATO:0001701 [Term] id: PATO:0001543 name: flexibility namespace: quality def: "A physical quality inhering in a bearer by virtue of the bearer's disposition to being turned, bowed, or twisted without breaking." [merriam-webster:merriam-webster] subset: attribute_slim subset: disposition_slim is_a: PATO:0001546 ! quality of a solid [Term] id: PATO:0001546 name: quality of a solid namespace: quality def: "A physical quality inhering in a bearer by virtue of the bearer's exhibiting the physical characteristics of an entity characterized by particles arranged such that their shape and volume are relatively stable." [Chemistry:http\://chemistry.about.com/od/chemistryglossary/a/soliddefinition.htm] subset: attribute_slim synonym: "solidity" EXACT [] is_a: PATO:0002198 ! quality of a substance [Term] id: PATO:0001547 name: quality of a gas namespace: quality def: "A physical quality inhering in a bearer by virtue of the bearer's exhibiting the physical characteristics of an entity consisting of particles that have neither a defined volume nor defined shape." [Chemistry:http\://chemistry.about.com/od/chemistryglossary/a/gasdefinition.htm, PATOC:GVG] subset: attribute_slim synonym: "gaseous" EXACT [] is_a: PATO:0002198 ! quality of a substance [Term] id: PATO:0001548 name: quality of a liquid namespace: quality def: "A physical quality inhering in an entity exhibiting the physical characteristics of an amorphous (non-crystalline) form of matter between a gas and a solid that has a definite volume, but no definite shape." [url:http\://www.chemistry-dictionary.com/definition/liquid.php] subset: attribute_slim synonym: "liquidity" EXACT [] is_a: PATO:0002198 ! quality of a substance [Term] id: PATO:0001555 name: has number of namespace: quality def: "The number of parts of a particular type that the bearer entity has. This is a relational quality, and thus holds between two entities: the bearer of the quality, and the type of parts." [PATOC:CJM] subset: attribute_slim subset: relational_slim synonym: "cardinality" RELATED [] synonym: "extra or missing physical or functional parts" EXACT [] synonym: "has or lacks parts of type" EXACT [] synonym: "mereological quality" EXACT [] synonym: "number" RELATED [] synonym: "number of" EXACT [] xref: OBO_REL:has_part is_a: PATO:0000070 ! amount [Term] id: PATO:0001571 name: dilated namespace: quality def: "A size quality inhering in a bearer by virtue of the bearer's being made wider or larger in all dimensions." [WordNet:WordNet] def: "A size quality inhering in a bearer by virtue of the bearer's being made wider or larger in all dimensions. [database_cross_reference: WordNet:WordNet]" [] subset: mpath_slim subset: value_slim is_a: PATO:0000586 ! increased size [Term] id: PATO:0001573 name: isometrical namespace: quality def: "A symmetry quality inhering in a bearer by virtue of the bearer's having equal dimensions or measurements." [WordNet:WordNet] def: "A symmetry quality inhering in a bearer by virtue of the bearer's having equal dimensions or measurements." [] subset: cell_quality subset: value_slim is_a: PATO:0000965 ! symmetry [Term] id: PATO:0001579 name: contractility namespace: quality def: "A physical quality that is the ability to contract or shrink." [WordNet:WordNet] subset: attribute_slim subset: disposition_slim subset: scalar_slim is_a: PATO:0001018 ! physical quality [Term] id: PATO:0001591 name: curvature namespace: quality def: "A surface shape quality inhering in a bearer by virtue of the bearer's exhibiting a degree of bending." [WordNet:WordNet] subset: attribute_slim is_a: PATO:0000052 ! shape [Term] id: PATO:0001690 name: contractile namespace: quality def: "A contractility quality inhering in a bearer by virtue of the bearer's ability of contracting or being contracted." [PATOC:GVG] comment: This refers to the disposition of the bearer. subset: disposition_slim subset: value_slim is_a: PATO:0001579 ! contractility property_value: RO:0002604 PATO:0001691 [Term] id: PATO:0001708 name: 1-D extent namespace: quality def: "A size quality inhering in an bearer by virtue of the bearer's extension in one dimension." [PATOC:GVG] subset: attribute_slim synonym: "1-D size" EXACT [] is_a: PATO:0000117 ! size [Term] id: PATO:0001735 name: liquid configuration namespace: quality def: "A physical quality inhering in a bearer by virtue of the bearer's parts having the arrangement which exhibits characteristics of liquids." [PATOC:GVG] synonym: "liquid" EXACT [] is_a: PATO:0001548 ! quality of a liquid [Term] id: PATO:0001736 name: solid configuration namespace: quality def: "A physical quality inhering in a bearer by virtue of the bearer's parts having the arrangement which exhibits characteristics of solids." [PATOC:GVG] subset: value_slim synonym: "solid" EXACT [] is_a: PATO:0001546 ! quality of a solid [Term] id: PATO:0001748 name: invaginated namespace: quality def: "A shape quality in which a portion of the outermost boundary of an entity folds in space such that a portion that was originally convex is now concave." [PATOC:GVG] subset: cell_quality subset: mpath_slim subset: value_slim is_a: PATO:0001857 ! concave [Term] id: PATO:0001794 name: coiling namespace: quality def: "A shape quality inhering in a bearer by virtue of the bearer's being wound in a continuous series of loops." [Online_Dictionary:Online_Dictionary] subset: attribute_slim is_a: PATO:0000052 ! shape [Term] id: PATO:0001795 name: increased coiling namespace: quality def: "A coiling which is relatively high." [PATOC:GVG] subset: cell_quality subset: value_slim synonym: "high coiling" EXACT [] is_a: PATO:0000404 ! coiled is_a: PATO:0002305 ! increased object quality intersection_of: PATO:0000404 ! coiled intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal property_value: RO:0002604 PATO:0001796 [Term] id: PATO:0001796 name: decreased coiling namespace: quality def: "A coiling which is relatively low." [PATOC:GVG] subset: cell_quality subset: value_slim synonym: "low coiling" EXACT [] is_a: PATO:0000404 ! coiled is_a: PATO:0002303 ! decreased object quality intersection_of: PATO:0000404 ! coiled intersection_of: RO:0015008 PATO:0000461 ! decreased in magnitude relative to normal property_value: RO:0002604 PATO:0001795 [Term] id: PATO:0001847 name: constricted namespace: quality alt_id: PATO:0001837 def: "A structural quality inhering in a bearer by virtue of the bearer's being drawn together, compressed or squeezed physically." [WordNet:WordNet] subset: value_slim synonym: "stenosis" EXACT [] synonym: "stenotic" EXACT [] synonym: "stricture" EXACT [] is_a: PATO:0000141 ! structure [Term] id: PATO:0001857 name: concave namespace: quality def: "A shape quality in a bearer by virtue of the bearer's curving inward." [WordNet:WordNet] subset: cell_quality subset: value_slim is_a: PATO:0002005 ! concavity property_value: RO:0002604 PATO:0001355 [Term] id: PATO:0001873 name: cylindrical namespace: quality alt_id: PATO:0001203 def: "A convex 3-D shape quality inhering in a bearer by virtue of the bearer's exhibiting a consistently-sized round cross section." [PATOC:MAH] subset: cell_quality subset: value_slim synonym: "rod-like" EXACT [] synonym: "rod-shaped" EXACT [] synonym: "tubulate" NARROW [] is_a: PATO:0002007 ! convex 3-D shape relationship: has_cross_section PATO:0000411 ! circular [Term] id: PATO:0001901 name: back namespace: quality def: "A directional quality inhering in a bearer by virtue of the bearer's direction that is similar to the direction of an object to the north when it faces south." [] def: "A directional quality inhering in a bearer by virtue of the bearer's direction that is similar to the direction of an object to the north when it faces south." [PATOC:GVG] subset: value_slim is_a: PATO:0000039 ! direction property_value: RO:0002604 PATO:0001900 [Term] id: PATO:0001908 name: multinucleate namespace: quality def: "A nucleate quality inhering in a bearer by virtue of the bearer's having more than one nucleus." [PATOC:GVG] subset: mpath_slim subset: value_slim is_a: PATO:0002505 ! nucleated [Term] id: PATO:0001987 name: saccular namespace: quality def: "A structural quality inhering in a bearer by virtue of the bearer's having a three dimensional cavity with a narrow or no opening, and often containing an anatomical substance." [PATOC:MAH] subset: value_slim synonym: "sacular" EXACT [] is_a: PATO:0002014 ! structure, cavities [Term] id: PATO:0001992 name: cellularity namespace: quality def: "An organismal quality inhering in a bearer by virtue of the bearer's consisting cells." [PATOC:GVG] subset: attribute_slim subset: scalar_slim is_a: PATO:0001995 ! organismal quality [Term] id: PATO:0001993 name: multicellular namespace: quality def: "A cellularity quality inhering in a bearer by virtue of the bearer's consisting of more than one cell." [PATOC:GVG] subset: value_slim is_a: PATO:0001992 ! cellularity [Term] id: PATO:0001995 name: organismal quality namespace: quality def: "A quality that inheres in an entire organism or part of an organism." [PATOC:CJM] is_a: PATO:0001241 ! physical object quality [Term] id: PATO:0001997 name: decreased amount namespace: quality alt_id: PATO:0000419 alt_id: PATO:0000468 def: "An amount which is relatively low." [PATOC:GVG] subset: value_slim synonym: "decreased" RELATED [] synonym: "decreased number" EXACT [] synonym: "present in fewer numbers in organism" EXACT [] synonym: "reduced" RELATED [] synonym: "subnumerary" RELATED [] is_a: PATO:0000467 ! present is_a: PATO:0002301 ! decreased quality intersection_of: PATO:0000070 ! amount intersection_of: RO:0015008 PATO:0000461 ! decreased in magnitude relative to normal property_value: RO:0002604 PATO:0000470 [Term] id: PATO:0002005 name: concavity namespace: quality def: "Surface shape that refers to the inward or outward curvature of the surface." [PATOC:MAH] subset: attribute_slim is_a: PATO:0000052 ! shape [Term] id: PATO:0002006 name: 2-D shape namespace: quality def: "A shape that inheres in a 2 dimensional entity, such as a cross section or projection of a 3 dimensional entity." [PATOC:CJM] subset: attribute_slim synonym: "2-D projection" RELATED [] synonym: "cross-sectional" RELATED [] is_a: PATO:0000052 ! shape [Term] id: PATO:0002007 name: convex 3-D shape namespace: quality def: "A complete three dimensional shape in which for every line connecting pair of points on the object is within the object. Or: a shape lacking cavities. Contrast: concave." [PATOC:CJM] comment: Use this term or an is_a child of this term when the entire shape of the object is known. subset: attribute_slim xref: Image:http\://upload.wikimedia.org/wikipedia/commons/0/06/Convex_polygon_illustration1.png is_a: PATO:0002266 ! 3-D shape relationship: has_cross_section PATO:0002006 ! 2-D shape property_value: RO:0002604 PATO:0002008 [Term] id: PATO:0002009 name: branchiness namespace: quality def: "A shape quality inhering in a bearer by virtue of the degree to which there are subdivisions or offshoots in a bearer entity." [PATOC:MAH] subset: attribute_slim subset: cell_quality is_a: PATO:0000052 ! shape [Term] id: PATO:0002014 name: structure, cavities namespace: quality def: "A structural quality that inheres in a bearer by virtue of the bearer's containing hollow areas." [PATOC:GVG] subset: attribute_slim is_a: PATO:0000141 ! structure [Term] id: PATO:0002021 name: conical namespace: quality def: "A convex 3-D shape quality inhering in a bearer by virtue of the bearer's resembling a cone (a 3-D shape with a round cross section that tapers)." [Wikipedia:http\://en.wikipedia.org/wiki/Cone_(geometry)] subset: value_slim synonym: "cone-shaped" EXACT [] xref: Image:http\://upload.wikimedia.org/wikipedia/commons/d/d2/Cone_3d.png is_a: PATO:0002007 ! convex 3-D shape [Term] id: PATO:0002039 name: biconcave namespace: quality def: "A concave quality inhering in a bearer by virtue of the bearer's curving inward on both sides or surfaces." [PATOC:GVG] subset: value_slim is_a: PATO:0001857 ! concave property_value: RO:0002604 PATO:0002040 [Term] id: PATO:0002045 name: dendritic namespace: quality def: "A branched quality inhering in a bearer by virtue of the bearer's having smaller branches arising from larger branches. Resembling a tree in branching structure." [PATOC:cvs] subset: value_slim synonym: "dendriform" EXACT [] synonym: "dendroid" EXACT [] synonym: "dendroidal" EXACT [] is_a: PATO:0000402 ! branched property_value: term:contributor https://orcid.org/0000-0002-2061-091X creation_date: 2009-02-15T08:11:41Z [Term] id: PATO:0002078 name: hollow namespace: quality def: "A quality inhering in a bearer by virtue of the bearer's having an empty space or cavity within." [url:http\://www.merriam-webster.com/dictionary/hollow] subset: value_slim is_a: PATO:0002014 ! structure, cavities property_value: term:contributor https://orcid.org/0000-0002-2061-091X creation_date: 2009-09-18T02:19:20Z [Term] id: PATO:0002094 name: basophilic namespace: quality def: "An affinity inhering in an anatomical structure by virtue of the bearer exhibiting a molecular interaction for basic dyes under specific pH conditions." [PATOC:GVG] subset: disposition_slim subset: mpath_slim subset: value_slim is_a: PATO:0070045 ! anatomical histological quality property_value: term:contributor https://orcid.org/0000-0002-2061-091X creation_date: 2009-10-05T12:05:23Z [Term] id: PATO:0002124 name: laminar namespace: quality def: "A quality inhering in a bearer by virtue of the bearer's processing the form of a thin plate sheet or layer." [PATOC:GVG] subset: mpath_slim subset: value_slim is_a: PATO:0000141 ! structure property_value: term:contributor https://orcid.org/0000-0002-2061-091X creation_date: 2009-10-06T04:37:14Z [Term] id: PATO:0002198 name: quality of a substance namespace: quality def: "A quality inhering in a bearer by virtue of its constitution." [PATOC:GVG] subset: attribute_slim is_a: PATO:0001018 ! physical quality property_value: term:contributor https://orcid.org/0000-0002-2061-091X creation_date: 2010-03-15T04:35:27Z [Term] id: PATO:0002219 name: fan-shaped namespace: quality def: "A quality inhering in a bearer that is shaped in the form of a fan." [thefreedictionary:http\://www.thefreedictionary.com/fan-shaped] subset: value_slim synonym: "fan-like" EXACT [] is_a: PATO:0002006 ! 2-D shape property_value: term:contributor https://orcid.org/0000-0002-2061-091X creation_date: 2010-07-09T01:43:42Z [Term] id: PATO:0002226 name: subcylindrical namespace: quality def: "A cylindrical shape quality inhering in a bearer by virtue of the bearer's being imperfectly cylindrical or approximately cylindrical." [url:http\://www.thefreedictionary.com/Subcylindrical] subset: value_slim is_a: PATO:0001873 ! cylindrical property_value: term:contributor https://orcid.org/0000-0002-2061-091X creation_date: 2010-07-13T04:22:30Z [Term] id: PATO:0002228 name: acuminate namespace: quality def: "A tapered shape quality inhering in a bearer by virtue of the bearer's tapering gradually to a sharp point." [url:http\://www.thefreedictionary.com/acuminate] subset: value_slim is_a: PATO:0001500 ! tapered property_value: term:contributor https://orcid.org/0000-0002-2061-091X creation_date: 2010-07-15T09:03:18Z [Term] id: PATO:0002254 name: flattened namespace: quality def: "A quality inhering in a bearer by virtue of the bearer's surface becoming more extended in a plane." [PATOC:CVS] comment: Becoming flat but not necessarily completely flat. subset: value_slim synonym: "compressed" RELATED [] is_a: PATO:0001591 ! curvature property_value: term:contributor https://orcid.org/0000-0002-2061-091X creation_date: 2010-08-16T03:59:34Z [Term] id: PATO:0002255 name: grooved namespace: quality def: "Texture quality inhering in a bearer by virtue of the bearer's being marked with one or more channels." [PATOC:JE] subset: value_slim synonym: "channeled" RELATED [] synonym: "creased" RELATED [] is_a: PATO:0000150 ! texture property_value: term:contributor https://orcid.org/0000-0002-2061-091X creation_date: 2010-09-01T10:27:48Z [Term] id: PATO:0002258 name: pointed namespace: quality def: "A shape quality inhering in a bearer by virtue of the bearer's having a point." [PATOC:http\://www.merriam-webster.com/dictionary/pointed] def: "A shape quality inhering in a bearer by virtue of the bearer's having a point." [] subset: value_slim is_a: PATO:0001419 ! sharp property_value: term:contributor https://orcid.org/0000-0002-2061-091X creation_date: 2010-09-08T03:15:16Z [Term] id: PATO:0002266 name: 3-D shape namespace: quality def: "A shape that inheres in a 3 dimensional entity." [PATOC:OREGON] is_a: PATO:0000052 ! shape property_value: term:contributor https://orcid.org/0000-0002-2061-091X creation_date: 2010-10-05T12:31:16Z [Term] id: PATO:0002287 name: increased elasticity namespace: quality def: "An elasticity which is relatively high." [PATOC:GVG] subset: value_slim is_a: PATO:0001171 ! elastic is_a: PATO:0002305 ! increased object quality intersection_of: PATO:0001171 ! elastic intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal property_value: RO:0002604 PATO:0002288 property_value: term:contributor https://orcid.org/0000-0002-2061-091X creation_date: 2011-03-30T11:50:21Z [Term] id: PATO:0002288 name: decreased elasticity namespace: quality def: "An elasticity which is relatively low." [PATOC:GVG] subset: value_slim is_a: PATO:0001171 ! elastic is_a: PATO:0002303 ! decreased object quality intersection_of: PATO:0001171 ! elastic intersection_of: RO:0015008 PATO:0000461 ! decreased in magnitude relative to normal property_value: RO:0002604 PATO:0002287 property_value: term:contributor https://orcid.org/0000-0002-2061-091X creation_date: 2011-03-30T11:50:39Z [Term] id: PATO:0002299 name: tubular namespace: quality def: "A cylindrical shape that is hollow." [PATOC:GVG] synonym: "tube like" EXACT [] synonym: "tube-shaped" EXACT [] synonym: "tubulate" EXACT [] is_a: PATO:0001873 ! cylindrical is_a: PATO:0002078 ! hollow property_value: term:contributor https://orcid.org/0000-0002-2061-091X creation_date: 2011-06-08T06:33:50Z [Term] id: PATO:0002300 name: increased quality namespace: quality def: "A quality that has a value that is increased compared to normal or average." [PATOC:GVG] is_a: PATO:0000069 ! deviation (from_normal) intersection_of: PATO:0000001 ! quality intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal relationship: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal property_value: RO:0002604 PATO:0002301 property_value: term:contributor https://orcid.org/0000-0002-2061-091X creation_date: 2011-06-16T06:39:43Z [Term] id: PATO:0002301 name: decreased quality namespace: quality def: "A quality that has a value that is decreased compared to normal or average." [PATOC:GVG] is_a: PATO:0000069 ! deviation (from_normal) intersection_of: PATO:0000001 ! quality intersection_of: RO:0015008 PATO:0000461 ! decreased in magnitude relative to normal relationship: RO:0015008 PATO:0000461 ! decreased in magnitude relative to normal property_value: RO:0002604 PATO:0002300 property_value: term:contributor https://orcid.org/0000-0002-2061-091X creation_date: 2011-06-16T06:40:15Z [Term] id: PATO:0002303 name: decreased object quality namespace: quality def: "A quality of an object that has a value that is decreased compared to normal or average." [PATOC:GVG] is_a: PATO:0001241 ! physical object quality is_a: PATO:0002301 ! decreased quality intersection_of: PATO:0001241 ! physical object quality intersection_of: RO:0015008 PATO:0000461 ! decreased in magnitude relative to normal property_value: RO:0002604 PATO:0002305 property_value: term:contributor https://orcid.org/0000-0002-2061-091X creation_date: 2011-06-16T06:51:54Z [Term] id: PATO:0002305 name: increased object quality namespace: quality def: "A quality of an object that has a value that is increased compared to normal or average." [PATOC:GVG] is_a: PATO:0001241 ! physical object quality is_a: PATO:0002300 ! increased quality intersection_of: PATO:0001241 ! physical object quality intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal property_value: RO:0002604 PATO:0002303 property_value: term:contributor https://orcid.org/0000-0002-2061-091X creation_date: 2011-06-16T06:54:01Z [Term] id: PATO:0002309 name: fiber shaped namespace: quality def: "A convex 3-D shape quality inhering in a bearer by virtue of the bearer's exhibiting a by virtue of the bearer's exhibiting a consistently sized and approximately round cross-section along its length, which is many times larger than its diameter." [PATOC:DC] comment: Note that a fiber shaped object may take any circuitous or straight path through space (think of a length of string or rope). subset: value_slim is_a: PATO:0002226 ! subcylindrical property_value: term:contributor https://orcid.org/0000-0002-2061-091X creation_date: 2011-09-09T04:50:10Z [Term] id: PATO:0002318 name: superelliptic namespace: quality def: "A shape constituting a transition between a rectangle and a circle; a closed curve, of which the circle and ellipse are special cases, whose parametric equation is x = a.cos2/rt, y = b.cos2/rt" [wiktionary:superellipse] synonym: "Lamé curve" EXACT [] is_a: PATO:0002006 ! 2-D shape property_value: term:contributor https://orcid.org/0000-0002-2061-091X creation_date: 2011-10-12T12:45:16Z [Term] id: PATO:0002418 name: acidophilic namespace: quality def: "An affinity inhering in an anatomical structure by virtue of the bearer exhibiting a molecular interaction for acidic dyes under specific pH conditions." [PATOC:GVG] comment: Eosin stains acidophilic structures, hence eosinophilic is the same as acidophilic. subset: mpath_slim subset: value_slim synonym: "eosinophilic" EXACT [] is_a: PATO:0070045 ! anatomical histological quality property_value: term:contributor https://orcid.org/0000-0002-2061-091X creation_date: 2012-12-17T03:01:19Z [Term] id: PATO:0002422 name: acinar namespace: quality def: "Pertaining to the individual parts making up an aggregate fruit like a many-lobed \"berry,\" such as a raspberry." [wikipedia:https\://en.wikipedia.org/wiki/Acinus] comment: Acinus is Latin for berry. subset: mpath_slim subset: value_slim is_a: PATO:0000141 ! structure property_value: term:contributor https://orcid.org/0000-0002-2061-091X creation_date: 2012-12-17T03:11:10Z [Term] id: PATO:0002462 name: collagenous namespace: quality def: "A composition quality inhering in an bearer by virtue of the bearer's consisting of collagen." [PATOC:WD] subset: value_slim is_a: PATO:0000025 ! composition property_value: term:contributor https://orcid.org/0000-0002-2061-091X creation_date: 2013-09-15T11:34:15Z [Term] id: PATO:0002468 name: distensible namespace: quality def: "A structure quality inhering in a bearer by virtue of the bearer's being capable of swelling or stretching." [PATOC:WD] subset: value_slim is_a: PATO:0015008 ! distensibility property_value: term:contributor https://orcid.org/0000-0002-2061-091X creation_date: 2013-09-15T11:48:26Z [Term] id: PATO:0002478 name: transversely striated namespace: quality def: "A shape quality inhering in a bearer by virtue of the bearer's being marked by narrow lines or grooves, usually parallel, that are oriented transversely relative to the long axis of the bearer." [PATOC:DS] subset: cell_quality subset: mpath_slim subset: value_slim is_a: PATO:0001410 ! striated property_value: term:contributor https://orcid.org/0000-0002-2061-091X creation_date: 2013-09-15T12:29:15Z [Term] id: PATO:0002505 name: nucleated namespace: quality def: "A nucleate quality inhering in a bearer by virtue of the bearer's having one or more nucleus." [PATOC:GVG] subset: mpath_slim subset: value_slim is_a: PATO:0001404 ! nucleate quality property_value: term:contributor https://orcid.org/0000-0002-2061-091X creation_date: 2013-10-21T05:44:34Z [Term] id: PATO:0002539 name: ring shaped namespace: quality def: "A shape quality inhering in a bearer by virtue of the bearer's having a shape like a ring (a circular shape enclosing a space)." [PATOC:WD] subset: value_slim synonym: "annular" EXACT [] synonym: "ring-shaped" EXACT [] is_a: PATO:0000947 ! elliptic property_value: term:contributor https://orcid.org/0000-0003-3162-7490 creation_date: 2014-08-12T12:01:56Z [Term] id: PATO:0010001 name: disconnected namespace: quality def: "A structural quality inhering in the bearer by virtue of the bearer consisting of multiple structures lacking any physical connection to each other." [GOC:dos] is_a: PATO:0000141 ! structure property_value: term:contributor https://orcid.org/0000-0002-7073-9172 creation_date: 2014-12-12T08:43:17Z [Term] id: PATO:0015006 name: polymeric namespace: quality def: "A quality inhering in a structure by virtue of it consisting of many of repeated, similar or identical subunits, arranged in some orderly array." [GOC:DOS, https://github.com/pato-ontology/pato/issues/78] comment: A complete coverage of this domain would subclasses homopolymeric, copolymeric, crystalline. subset: value_slim is_a: PATO:0000141 ! structure [Term] id: PATO:0015008 name: distensibility namespace: quality def: "A quality inhering in a bearer by virtue of the extent to which the bearer is capable of being stretched or swollen." [GOC:CJM] subset: attribute_slim is_a: PATO:0000141 ! structure [Term] id: PATO:0015024 name: increased porosity namespace: quality def: "An increase in porosity." [https://github.com/pato-ontology/pato/issues/110] subset: value_slim is_a: PATO:0000973 ! porosity is_a: PATO:0002305 ! increased object quality intersection_of: PATO:0000973 ! porosity intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal [Term] id: PATO:0015025 name: decreased porosity namespace: quality def: "An decrease in porosity." [https://github.com/pato-ontology/pato/issues/110] subset: value_slim is_a: PATO:0000973 ! porosity is_a: PATO:0002303 ! decreased object quality intersection_of: PATO:0000973 ! porosity intersection_of: RO:0015008 PATO:0000461 ! decreased in magnitude relative to normal property_value: RO:0002604 PATO:0015024 [Term] id: PATO:0040024 name: bilaterally paired namespace: quality def: "The bearer of this quality has_part n=2 of the indicated entity type, where n is unpaired for a comparable organism." [https://orcid.org/0000-0003-3162-7490] synonym: "paired" BROAD [] is_a: PATO:0000467 ! present property_value: term:contributor https://orcid.org/0000-0001-5208-3432 [Term] id: PATO:0040072 name: high nuclear/cytoplasmic ratio namespace: quality def: "A quality inhering in a cell by virtue of the cell having a high nuclear/cytoplasmic ratio." [http://lymerick.net/blood-cells.pdf, Wikipedia:NC_ratio&oldid=931936284] comment: A high nuclear/cytolasmic ratio is 70% or higher. synonym: "high N:C ratio" EXACT [] is_a: PATO:0001396 ! cellular quality created_by: http://orcid.org/0000-0001-5208-3432 [Term] id: PATO:0070044 name: anatomical structure quality namespace: quality def: "A quality of continuant that exist at the anatomical level of organisation and anything under it. This includes, but is not limited to, cells , tissues, and components." [] is_a: PATO:0001241 ! physical object quality created_by: http://orcid.org/0000-0001-7258-9596 [Term] id: PATO:0070045 name: anatomical histological quality namespace: quality def: "A quality inhering in an anotomical structure by virtue of its capacity to be stained by specific histological dyes." [] is_a: PATO:0070044 ! anatomical structure quality created_by: http://orcid.org/0000-0001-7258-9596 [Term] id: PATO:0070046 name: neutrophillic namespace: quality def: "An affinity inhering in an anatomical structure by virtue of the bearer exhibiting a molecular interaction that stains and colors, pale-pink, with Wright-Giemsa stain." [GOC:add] is_a: PATO:0070045 ! anatomical histological quality created_by: http://orcid.org/0000-0001-7258-9596 [Term] id: PATO:0070047 name: polychromatophilic namespace: quality def: "An affinity inhering in an anatomical structure by virtue of the bearer exhibiting a molecular interaction for both basic and acid stains under specific pH conditions." [GOC:add] is_a: PATO:0070045 ! anatomical histological quality created_by: http://orcid.org/0000-0001-7258-9596 [Term] id: PATO:0070060 name: quality of interaction of a substance with electromagnetic radiation namespace: quality def: "A quality of a substance on which or through which electromagnetic radiation impinges or traverses with respect to radiation. This substance quality changes the quality of the incident radiation with respect to any of: intensity, direction, scatter and wavelength." [https://orcid.org/0000-0002-5111-7263] subset: attribute_slim is_a: PATO:0002198 ! quality of a substance [Term] id: PATO:0103000 name: quantitative namespace: quality def: "A quality of an entity that can be represented numerically, including anything that can be counted, measured, or given a numerical value." [https://libguides.macalester.edu/c.php?g=527786&p=3608639, https://www.nnlm.gov/guides/data-glossary/quantitative-data] is_a: PATO:0000001 ! quality created_by: https://orcid.org/0000-0001-8314-2140 [Term] id: PR:000000001 name: protein namespace: protein def: "An amino acid chain that is produced de novo by ribosome-mediated translation of a genetically-encoded mRNA, and any derivatives thereof." [PRO:DAN, PRO:WCB] comment: The definition above excludes protein complexes, which some also consider a protein. Those who wish to refer to a class representing both senses of the word are directed to CHEBI:36080. Note that the definition allows for experimentally-manipulated genes, and allows for artifically-produced derivatives that mimic those found naturally. Proteins (in the sense defined here) that descended from a common ancestor can be classified into families and superfamilies composed of products of evolutionarily-related genes. The domain architecture of a protein is described by the order of its constituent domains. Proteins with the same domains in the same order are defined as homeomorphic [PRO:WCB]. synonym: "native protein" NARROW [IEDB:BP] synonym: "natural protein" EXACT [PRO:DAN] is_a: PR:000018263 ! amino acid chain is_a: PR:000050567 ! protein-containing material entity intersection_of: PR:000018263 ! amino acid chain intersection_of: has_gene_template SO:0000704 ! gene intersection_of: output_of GO:0006412 ! translation relationship: has_gene_template SO:0000704 ! gene relationship: output_of GO:0006412 ! translation [Term] id: PR:000001002 name: CD19 molecule namespace: protein def: "A protein that is a translation product of the human CD19 gene or a 1:1 ortholog thereof. It is composed of an N-terminal extracellular domain containing two Ig-like C2-type (immunoglobulin-like) domains, followed by a single-pass transmembrane segment and a cytoplasmic C-terminal tail. CD19 expression is restricted to members of the B cell lineage. It functions as a co-receptor for B-cell antigen receptor (BCR), regulating signal transduction." [PMID:15778510] comment: Category=gene. Requested by=CL. synonym: "B-lymphocyte surface antigen B4" EXACT [] synonym: "CD19" EXACT PRO-short-label [PRO:DNx] synonym: "differentiation antigen CD19" EXACT [] synonym: "T-cell surface antigen Leu-12" EXACT [] xref: IUPHARobj:2764 xref: PIRSF:PIRSF016630 is_a: PR:000000001 ! protein [Term] id: PR:000001003 name: CD34 molecule namespace: protein def: "A protein that is a translation product of the human CD34 gene or a 1:1 ortholog thereof. It is a leukocyte membrane protein expressed specifically by lymphohematopoietic progenitor cells. It contains a single-pass transmembrane domain and that show distinct expression on early hematopoietic precursors and vascular-associated tissue. Acts as a scaffold that presents selectin carbohydrate ligands in a clustered, tissue specific manner to allow for higher avidity interactions between leukocytes and endothelial cells during the inflammatory process. In common with related sialomucins (endoglycan and podocalyxin), the extracellular region is dominated by an N-terminal mucin-like domain, which is densely substituted with sialylated O-linked carbohydrates. The mucin-like region is followed by a cysteine-containing and presumably globular domain. This domain may fold into an immunoglobulin-like structure as the positions of 2 of the cysteines are conserved in the C2 set of the immunoglobulin superfamily. The cytoplasmic domain is around 73-76 residues long and highly conserved." [PMID:16720896, PMID:8983065] comment: Category=gene. Requested by=CL. synonym: "CD34" EXACT PRO-short-label [PRO:DNx] synonym: "hematopoietic progenitor cell antigen CD34" EXACT [] xref: PIRSF:PIRSF028749 is_a: PR:000000001 ! protein [Term] id: PR:000001004 name: CD4 molecule namespace: protein def: "A protein that is a translation product of the human CD4 gene or a 1:1 ortholog thereof. CD4 is an accessory protein for MHC class-II antigen/T-cell receptor interaction. It is the primary receptor for HIV-1. CD4 has four immunoglobulin-like domains in its extracellular region that share the same structure, but can differ in sequence." [PMID:15326605] comment: Category=gene. Requested by=CL. synonym: "CD4" EXACT PRO-short-label [PRO:DNx] synonym: "T-cell differentiation antigen L3T4" EXACT [] synonym: "T-cell surface antigen T4/Leu-3" EXACT [] synonym: "T-cell surface glycoprotein CD4" EXACT [] xref: PIRSF:PIRSF001977 is_a: PR:000000001 ! protein [Term] id: PR:000001005 name: integrin alpha with A domain namespace: protein def: "An integrin alpha that contains an A domain. A hallmark of this class is the presence of a von Willebrand factor type A domain (Pfam:PF00092) (I-domain) of approximately 200 amino acid residues at the N terminus, which confers divalent cation binding properties. Unlike other integrin alpha proteins, they do not undergo proteolytic cleavage." [PIRSF:PIRSF002497] comment: Category=family. synonym: "integrin alpha with I domain" EXACT [] xref: PIRSF:PIRSF002497 is_a: PR:000025796 ! integrin alpha [Term] id: PR:000001012 name: integrin alpha-M namespace: protein def: "An integrin alpha with A domain that is a translation product of the human ITGAM gene or a 1:1 ortholog thereof. They constitute subunits of the integrin alpha-M/beta-2 receptor. This receptor is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is also a receptor for fibrinogen, factor X and ICAM1." [UniProtKB:P11215] comment: Category=gene. Requested by=CL. synonym: "CD11 antigen-like family member B" EXACT [] synonym: "CD11B" RELATED Gene-based [] synonym: "CD11b" EXACT [] synonym: "cell surface glycoprotein MAC-1 subunit alpha" EXACT [] synonym: "CR-3 alpha chain" EXACT [] synonym: "CR3A" RELATED Gene-based [] synonym: "ITGAM" EXACT PRO-short-label [PRO:DNx] synonym: "leukocyte adhesion receptor MO1" EXACT [] synonym: "neutrophil adherence receptor" EXACT [] xref: IUPHARobj:2452 is_a: PR:000001005 ! integrin alpha with A domain property_value: vocab:crossSpeciesExactMatch PR:P11215 [Term] id: PR:000001018 name: CD3 subunit with immunoglobulin domain namespace: protein def: "A protein that has a core domain composition consisting of an extracellular N-terminal domain that adopts an immunoglobulin fold, a transmembrane domain, and an intracellular C-terminal domain with a single copy of the Immunoreceptor tyrosine-based activation motif (Pfam:PF02189) (ITAM). It constitutes the invariant subunit of the T cell antigen receptor (TCR). TCR is a surface receptor on T cells responsible for recognizing MHC-restricted antigens and initiating the cellular immune response." [PMID:16473826, PMID:1724736] comment: Category=family. synonym: "CD3 subunit with Ig-like domain" EXACT [] xref: PIRSF:PIRSF001993 is_a: PR:000000001 ! protein [Term] id: PR:000001020 name: CD3 epsilon namespace: protein def: "A CD3 subunit with immunoglobulin domain that is a translation product of the human CD3E gene or a 1:1 ortholog thereof." [PRO:CNA] comment: Category=gene. Requested by=CL. synonym: "CD3E" EXACT PRO-short-label [PRO:DNx] synonym: "CD3e" EXACT [] synonym: "T-cell surface antigen T3/Leu-4 epsilon chain" EXACT [] synonym: "T3E" RELATED Gene-based [] xref: IUPHARobj:2742 is_a: PR:000001018 ! CD3 subunit with immunoglobulin domain [Term] id: PR:000001022 name: neural cell adhesion molecule namespace: protein def: "A protein with a domain composition consisting of a large extracellular domain, including five Ig-like C2-type domains followed by two copies of the Fibronectin type-III domain (Pfam:PF00041), a single-pass transmembrane domain and a short cytoplasmic C-terminal domain." [PRO:CNA] comment: Category=family. xref: PIRSF:PIRSF002507 is_a: PR:000000001 ! protein [Term] id: PR:000001023 name: neural cell adhesion molecule NCAM namespace: protein def: "A neural cell adhesion molecule that is involved in neuronal development, synaptic plasticity, and regeneration." [PMID:17975827] comment: Category=family. xref: PIRSF:PIRSF501037 is_a: PR:000001022 ! neural cell adhesion molecule [Term] id: PR:000001024 name: neural cell adhesion molecule 1 namespace: protein def: "A neural cell adhesion molecule NCAM that is a translation product of the human NCAM1 gene or a 1:1 ortholog thereof." [PRO:CNA] comment: Category=gene. Requested by=CL. synonym: "CD56" EXACT [] synonym: "N-CAM-1" EXACT [] synonym: "NCAM" RELATED Gene-based [] synonym: "NCAM-1" EXACT [] synonym: "NCAM1" EXACT PRO-short-label [PRO:DNx] xref: IUPHARobj:2769 is_a: PR:000001023 ! neural cell adhesion molecule NCAM property_value: vocab:crossSpeciesExactMatch PR:P13591 [Term] id: PR:000001083 name: CD2 molecule namespace: protein def: "A protein that is a translation product of the human CD2 gene or a 1:1 ortholog thereof." [PRO:CNA] comment: Category=gene. Requested by=CL. synonym: "CD2" EXACT PRO-short-label [PRO:DNx] synonym: "erythrocyte receptor" EXACT [] synonym: "LFA-2" EXACT [] synonym: "LFA-3 receptor" EXACT [] synonym: "ly-37" EXACT [] synonym: "lymphocyte antigen 37" EXACT [] synonym: "rosette receptor" EXACT [] synonym: "SRBC" RELATED Gene-based [] synonym: "T-cell surface antigen CD2" EXACT [] synonym: "T-cell surface antigen T11/Leu-5" EXACT [] synonym: "T-cell surface glycoprotein CD2" EXACT [] xref: IUPHARobj:2600 xref: PIRSF:PIRSF001984 is_a: PR:000000001 ! protein [Term] id: PR:000001084 name: T-cell surface glycoprotein CD8 alpha chain namespace: protein def: "A protein that is a translation product of the human CD8A gene or a 1:1 ortholog thereof. CD8 is a transmembrane that is a co-receptor for MHC class-I antigen/T-cell receptor interaction. The most common form of CD8 is composed of a CD8 alpha and a CD8 beta chain." [PMID:11114424, PRO:CNA, Wikipedia:CD8] comment: Category=gene. Requested by=CL. synonym: "CD8A" EXACT PRO-short-label [PRO:DNx] synonym: "CD8a" EXACT [] synonym: "Lyt-2" RELATED Gene-based [] synonym: "Lyt2" RELATED Gene-based [] synonym: "MAL" RELATED Gene-based [] synonym: "T-cell surface glycoprotein Lyt-2" EXACT [] synonym: "T-lymphocyte differentiation antigen T8/Leu-2" EXACT [] is_a: PR:000000001 ! protein property_value: vocab:crossSpeciesExactMatch PR:P01732 [Term] id: PR:000001289 name: membrane-spanning 4-domains subfamily A member 1 namespace: protein def: "A protein that is a translation product of the human MS4A1 gene or a 1:1 ortholog thereof." [PRO:WCB] comment: Category=gene. Requested by=CL. synonym: "B-cell differentiation antigen Ly-44" EXACT [] synonym: "B-cell surface antigen CD20" EXACT [] synonym: "B-lymphocyte antigen CD20" EXACT [] synonym: "B-lymphocyte surface antigen B1" EXACT [] synonym: "Bp35" EXACT [] synonym: "CD20" RELATED Gene-based [] synonym: "leukocyte surface antigen Leu-16" EXACT [] synonym: "Ly-44" RELATED Gene-based [] synonym: "lymphocyte antigen 44" EXACT [] synonym: "MS4A1" EXACT PRO-short-label [PRO:DNx] synonym: "Ms4a2" RELATED Gene-based [] xref: IUPHARobj:2628 xref: PIRSF:PIRSF001995 is_a: PR:000000001 ! protein [Term] id: PR:000001327 name: cadherin namespace: protein def: "A protein that has a core domain structure of signal sequence, propeptide, five Cadherin domains (Pfam:PF00028), a transmembrane region, and a Cadherin cytoplasmic region (Pfam:PF01049). Cadherins function as adhesion molecules that mediate Ca2+-dependent cell-cell adhesion in solid tissues." [PRO:WCB] comment: Category=family. xref: PIRSF:PIRSF002504 is_a: PR:000000001 ! protein [Term] id: PR:000001444 name: cadherin-5 namespace: protein def: "A cadherin that is a translation product of the human CDH5 gene or a 1:1 ortholog thereof." [PRO:WCB] comment: Category=gene. Requested by=CL. synonym: "7B4 antigen" EXACT [] synonym: "CD144" EXACT [] synonym: "CDH5" EXACT PRO-short-label [PRO:DNx] synonym: "vascular endothelial cadherin" EXACT [] synonym: "VE-cadherin" EXACT [] is_a: PR:000001327 ! cadherin property_value: vocab:crossSpeciesExactMatch PR:P33151 [Term] id: PR:000001839 name: T-cell surface glycoprotein CD5 namespace: protein def: "A protein that is a translation product of the human CD5 gene or a 1:1 ortholog thereof." [PRO:WCB] comment: Category=gene. Requested by=CL. synonym: "CD5" EXACT PRO-short-label [PRO:DNx] synonym: "LEU1" RELATED Gene-based [] synonym: "ly-1" EXACT [] synonym: "lymphocyte antigen 1" EXACT [] synonym: "lymphocyte antigen T1/Leu-1" EXACT [] synonym: "Lyt-1" EXACT [] is_a: PR:000000001 ! protein property_value: vocab:crossSpeciesExactMatch PR:P06127 [Term] id: PR:000001869 name: interleukin-7 receptor subunit alpha namespace: protein def: "A protein that is a translation product of the human IL7R gene or a 1:1 ortholog thereof." [PRO:WCB] comment: Category=gene. Requested by=CL. synonym: "CD127" EXACT [] synonym: "CDw127" EXACT [] synonym: "IL-7 receptor subunit alpha" EXACT [] synonym: "IL-7R subunit alpha" EXACT [] synonym: "IL-7R-alpha" EXACT [] synonym: "IL-7RA" EXACT [] synonym: "IL7R" EXACT PRO-short-label [PRO:DNx] xref: IUPHARobj:1698 xref: PIRSF:PIRSF001960 is_a: PR:000000001 ! protein property_value: vocab:crossSpeciesExactMatch PR:P16871 [Term] id: PR:000001889 name: CD14 molecule namespace: protein def: "A protein that is a translation product of the human CD14 gene or a 1:1 ortholog thereof." [PRO:WCB] comment: Category=gene. Requested by=CL. synonym: "CD14" EXACT PRO-short-label [PRO:DNx] synonym: "monocyte differentiation antigen CD14" EXACT [] synonym: "myeloid cell-specific leucine-rich glycoprotein" EXACT [] xref: PIRSF:PIRSF002017 is_a: PR:000000001 ! protein [Term] id: PR:000001945 name: transferrin receptor protein 1 namespace: protein def: "A protein that is a translation product of the human TFRC gene or a 1:1 ortholog thereof." [PRO:WCB] comment: Category=gene. Requested by=CL. synonym: "CD71" EXACT [] synonym: "p90" BROAD [PRO:DNx] synonym: "T9" EXACT [] synonym: "TfR" EXACT [] synonym: "TfR1" EXACT [] synonym: "TFRC" EXACT PRO-short-label [PRO:DNx] synonym: "TR" RELATED [] synonym: "Trfr" RELATED Gene-based [] is_a: PR:000000001 ! protein property_value: vocab:crossSpeciesExactMatch PR:P02786 [Term] id: PR:000001971 name: vascular endothelial growth factor receptor namespace: protein def: "A protein with core architecture consisting of a signal sequence, followed by 7 Ig-like domains (Pfam:PF00047, Pfam:PF07679, or Pfam:PF07686), a transmembrane region, and a cytoplasmic Protein tyrosine kinase domain." [PRO:WCB] comment: Category=family. xref: PIRSF:PIRSF038502 is_a: PR:000000001 ! protein [Term] id: PR:000002112 name: vascular endothelial growth factor receptor 2 namespace: protein def: "A vascular endothelial growth factor receptor that is a translation product of the human KDR gene or a 1:1 ortholog thereof." [PRO:WCB] comment: Category=gene. Requested by=CL. synonym: "CD309" EXACT [] synonym: "fetal liver kinase 1" EXACT [] synonym: "FLK-1" EXACT [] synonym: "FLK1" RELATED Gene-based [] synonym: "KDR" EXACT PRO-short-label [PRO:DNx] synonym: "kinase insert domain receptor" EXACT [] synonym: "kinase NYK" EXACT [] synonym: "protein-tyrosine kinase receptor flk-1" EXACT [] synonym: "VEGFR-2" EXACT [] synonym: "VEGFR2" RELATED Gene-based [] xref: IUPHARobj:1813 is_a: PR:000001971 ! vascular endothelial growth factor receptor property_value: vocab:crossSpeciesExactMatch PR:P35968 [Term] id: PR:000002976 name: Ly-6-like protein namespace: protein def: "A protein that is the translation product of any of the LY6 genes (LY6A-LY6I)." [PRO:CNA] comment: Category=family. xref: PIRSF:PIRSF002021 is_a: PR:000000001 ! protein [Term] id: PR:000002978 name: lymphocyte antigen 6G namespace: protein def: "An Ly-6-like protein that is a translation product of the mouse Ly6g gene or a 1:1 ortholog thereof." [PRO:CNA] comment: Category=gene. Requested by=CL. synonym: "Ly-6G" EXACT [] synonym: "Ly-6G.1" EXACT [] synonym: "Ly6g" EXACT PRO-short-label [PRO:DNx] is_a: PR:000002976 ! Ly-6-like protein [Term] id: PR:000002981 name: lymphocyte antigen 76 (mouse) namespace: protein def: "A protein that is a translation product of the Ly76 gene in mouse." [PMID:10848813, PRO:DAN] comment: Category=organism-gene. Requested by=CL. synonym: "mLy76" EXACT PRO-short-label [PRO:DNx] synonym: "ter-119" EXACT [] synonym: "ter119" EXACT [] is_a: PR:000029032 ! Mus musculus protein [Term] id: PR:000007499 name: fibroblast growth factor 8 namespace: protein def: "A protein that is a translation product of the human FGF8 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "AIGF" RELATED Gene-based [] synonym: "androgen-induced growth factor" EXACT [] synonym: "FGF-8" EXACT [] synonym: "FGF8" EXACT PRO-short-label [PRO:DNx] synonym: "HBGF-8" RELATED [] synonym: "heparin-binding growth factor 8" RELATED [] is_a: PR:000000001 ! protein property_value: vocab:crossSpeciesExactMatch PR:P55075 [Term] id: PR:000009054 name: insulin gene translation product namespace: protein def: "An insulin family protein that is a translation product of the human INS gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "INS" EXACT PRO-short-label [PRO:DNx] synonym: "insulin" BROAD [PRO:DAN] is_a: PR:000045358 ! insulin family protein property_value: vocab:crossSpeciesExactMatch PR:P01308 [Term] id: PR:000014841 name: sonic hedgehog protein namespace: protein def: "A protein that is a translation product of the human SHH gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "HHG-1" EXACT [] synonym: "Hhg1" RELATED Gene-based [] synonym: "SHH" EXACT PRO-short-label [PRO:DNx] synonym: "Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains" EXACT [] synonym: "ShhNC" EXACT [] is_a: PR:000000001 ! protein property_value: vocab:crossSpeciesExactMatch PR:Q15465 [Term] id: PR:000016043 name: T-cell acute lymphocytic leukemia protein 1 namespace: protein def: "A protein that is a translation product of the human TAL1 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. Requested by=CL. synonym: "BHLHA17" RELATED Gene-based [] synonym: "bHLHa17" EXACT [] synonym: "class A basic helix-loop-helix protein 17" EXACT [] synonym: "SCL" RELATED Gene-based [] synonym: "stem cell protein" EXACT [] synonym: "T-cell leukemia/lymphoma protein 5" EXACT [] synonym: "TAL-1" EXACT [] synonym: "TAL1" EXACT PRO-short-label [PRO:DNx] synonym: "TCL5" RELATED Gene-based [] is_a: PR:000000001 ! protein property_value: vocab:crossSpeciesExactMatch PR:P17542 [Term] id: PR:000018263 name: amino acid chain namespace: protein def: "An organic amino compound that consists of amino acid residues (unmodified amino-acid residues and/or modified amino-acid residues) linked by peptide bonds or derivatives of such bonds." [PRO:DAN, PRO:JSG] comment: Category=polymer. synonym: "peptide" NARROW [PRO:DAN] synonym: "polypeptide" NARROW [PRO:DAN] is_a: CHEBI:50047 ! organic amino compound relationship: has_constituent_monomer CHEBI:33708 {minCardinality="2"} ! amino-acid residue [Term] id: PR:000025796 name: integrin alpha namespace: protein def: "A protein that is composed of a long N-terminal extracellular domain, a transmembrane domain and a short cytoplasmic C-terminal domain. The N-terminal domain contains beta-propeller repeats (interrupted by an A domain in a subset of integrins alpha), while the C-terminal domain contains a GFFxR motif." [PMID:19693543] comment: Category=family. Integrins are heterodimeric complexes of an alpha and a beta subunit. They are a structurally elaborate family of adhesion molecules that transmit signals bidirectionally across the plasma membrane by undergoing large-scale structural rearrangements. By regulating cell-cell and cell-matrix contacts, integrins participate in a wide-range of biological interactions including development, tissue repair, angiogenesis, inflammation and hemostasis. [PMID:10402956, PMID:11988479, PMID:9676575]. is_a: PR:000000001 ! protein [Term] id: PR:000029032 name: Mus musculus protein namespace: protein def: "A protein that is encoded in the genome of Mus musculus." [PRO:DAN] synonym: "mouse protein" EXACT PRO-short-label [PRO:DAN] is_a: PR:000036194 ! eukaryotic protein intersection_of: PR:000000001 ! protein intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:000029060 name: Drosophila melanogaster protein namespace: protein def: "A protein that is encoded in the genome of Drosophila melanogaster." [PRO:DAN] synonym: "fruit fly protein" EXACT PRO-short-label [PRO:DAN] is_a: PR:000036194 ! eukaryotic protein intersection_of: PR:000000001 ! protein intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster relationship: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster [Term] id: PR:000029067 name: Homo sapiens protein namespace: protein def: "A protein that is encoded in the genome of Homo sapiens." [PRO:DAN] synonym: "human protein" EXACT PRO-short-label [PRO:DAN] is_a: PR:000036194 ! eukaryotic protein intersection_of: PR:000000001 ! protein intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000036194 name: eukaryotic protein namespace: protein def: "A protein that is encoded in the genome of some Eukaryota." [PRO:DAN] synonym: "Eukaryota protein" EXACT [PRO:DAN] is_a: PR:000000001 ! protein intersection_of: PR:000000001 ! protein intersection_of: only_in_taxon NCBITaxon:2759 ! Eukaryota relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota [Term] id: PR:000045358 name: insulin family protein namespace: protein def: "A protein that is a translation product of a gene that encodes a standalone Insulin (Pfam:PF00049) domain preceded by a signal peptide." [PRO:DAN] comment: Category=family. synonym: "fam:INS" EXACT PRO-short-label [PRO:DAN] is_a: PR:000000001 ! protein [Term] id: PR:000050567 name: protein-containing material entity namespace: protein def: "A material entity that minimally consists of a protein." [PRO:DAN] comment: Note: This includes single proteins and derivatives thereof (PR:000000001), protein-containing complexes (GO:0032991), and protein aggregates (PR:000050566). synonym: "protein" NARROW [PRO:DAN] synonym: "protein aggregate" NARROW [PRO:DAN] synonym: "protein complex" NARROW [PRO:DAN] synonym: "protein-containing complex" NARROW [PRO:DAN] is_a: BFO:0000040 ! material entity intersection_of: BFO:0000040 ! material entity intersection_of: has_part PR:000000001 ! protein relationship: has_part PR:000000001 ! protein [Term] id: PR:P01308 name: insulin gene translation product (human) namespace: protein def: "An insulin gene translation product that is encoded in the genome of human." [PRO:DAN, UniProtKB:P01308] comment: Category=organism-gene. synonym: "hINS" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P01308 is_a: PR:000009054 ! insulin gene translation product is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000009054 ! insulin gene translation product intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P01730 name: T-cell surface glycoprotein CD4 (human) namespace: protein def: "A CD4 molecule that is encoded in the genome of human." [PRO:DNx, UniProtKB:P01730] comment: Category=organism-gene. synonym: "CD4" RELATED Gene-based [UniProtKB:P01730] synonym: "hCD4" EXACT PRO-short-label [PRO:DNx] synonym: "T-cell surface antigen T4/Leu-3 (human)" EXACT [UniProtKB:P01730] xref: UniProtKB:P01730 is_a: PR:000001004 ! CD4 molecule is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000001004 ! CD4 molecule intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P01731 name: T-cell surface glycoprotein CD8 alpha chain (mouse) namespace: protein def: "A T-cell surface glycoprotein CD8 alpha chain that is encoded in the genome of mouse." [OMA:P01731, PRO:DNx] comment: Category=organism-gene. synonym: "Cd8a" RELATED Gene-based [UniProtKB:P01731] synonym: "CD8a (mouse)" EXACT [UniProtKB:P01731] synonym: "Lyt-2" RELATED Gene-based [UniProtKB:P01731] synonym: "Lyt2" RELATED Gene-based [UniProtKB:P01731] synonym: "mCD8A" EXACT PRO-short-label [PRO:DNx] synonym: "T-cell surface glycoprotein Lyt-2 (mouse)" EXACT [UniProtKB:P01731] xref: UniProtKB:P01731 is_a: PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P01732 name: T-cell surface glycoprotein CD8 alpha chain (human) namespace: protein def: "A T-cell surface glycoprotein CD8 alpha chain that is encoded in the genome of human." [PRO:CNA, UniProtKB:P01732] comment: Category=organism-gene. synonym: "CD8A" RELATED Gene-based [UniProtKB:P01732] synonym: "CD8a (human)" EXACT [UniProtKB:P01732] synonym: "hCD8A" EXACT PRO-short-label [PRO:DNx] synonym: "MAL" RELATED Gene-based [UniProtKB:P01732] synonym: "T-lymphocyte differentiation antigen T8/Leu-2 (human)" EXACT [UniProtKB:P01732] xref: UniProtKB:P01732 is_a: PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P02786 name: transferrin receptor protein 1 (human) namespace: protein def: "A transferrin receptor protein 1 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P02786] comment: Category=organism-gene. synonym: "CD71 (human)" EXACT [UniProtKB:P02786] synonym: "hTFRC" EXACT PRO-short-label [PRO:DNx] synonym: "p90 (human)" BROAD [UniProtKB:P02786] synonym: "T9 (human)" EXACT [UniProtKB:P02786] synonym: "TfR (human)" EXACT [UniProtKB:P02786] synonym: "TfR1 (human)" EXACT [UniProtKB:P02786] synonym: "TFRC" RELATED Gene-based [UniProtKB:P02786] synonym: "TR (human)" BROAD [UniProtKB:P02786] synonym: "Trfr (human)" EXACT [UniProtKB:P02786] xref: Reactome:R-HSA-434196 "PR:P02786 located_in GO:0030659" xref: Reactome:R-HSA-434330 "PR:P02786 located_in GO:0000139" xref: Reactome:R-HSA-8869124 "PR:P02786 located_in GO:0030665" xref: Reactome:R-HSA-8961829 "PR:P02786 located_in GO:0010008" xref: Reactome:R-HSA-917983 "PR:P02786 located_in GO:0005886" xref: UniProtKB:P02786 is_a: PR:000001945 ! transferrin receptor protein 1 is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000001945 ! transferrin receptor protein 1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P05555 name: integrin alpha-M (mouse) namespace: protein def: "An integrin alpha-M that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:P05555] comment: Category=organism-gene. synonym: "CD11 antigen-like family member B (mouse)" EXACT [UniProtKB:P05555] synonym: "CD11b (mouse)" EXACT [UniProtKB:P05555] synonym: "cell surface glycoprotein MAC-1 subunit alpha (mouse)" EXACT [UniProtKB:P05555] synonym: "CR-3 alpha chain (mouse)" EXACT [UniProtKB:P05555] synonym: "Itgam" RELATED Gene-based [UniProtKB:P05555] synonym: "leukocyte adhesion receptor MO1 (mouse)" EXACT [UniProtKB:P05555] synonym: "mITGAM" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P05555 is_a: PR:000001012 ! integrin alpha-M is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000001012 ! integrin alpha-M intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P06127 name: T-cell surface glycoprotein CD5 (human) namespace: protein def: "A T-cell surface glycoprotein CD5 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P06127] comment: Category=organism-gene. synonym: "CD5" RELATED Gene-based [UniProtKB:P06127] synonym: "hCD5" EXACT PRO-short-label [PRO:DNx] synonym: "LEU1" RELATED Gene-based [UniProtKB:P06127] synonym: "lymphocyte antigen T1/Leu-1 (human)" EXACT [UniProtKB:P06127] xref: UniProtKB:P06127 is_a: PR:000001839 ! T-cell surface glycoprotein CD5 is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000001839 ! T-cell surface glycoprotein CD5 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P06332 name: T-cell surface glycoprotein CD4 (mouse) namespace: protein def: "A CD4 molecule that is encoded in the genome of mouse." [OMA:P06332, PRO:DNx] comment: Category=organism-gene. synonym: "Cd4" RELATED Gene-based [UniProtKB:P06332] synonym: "CD4 (mouse)" EXACT [UniProtKB:P06332] synonym: "mCD4" EXACT PRO-short-label [PRO:DNx] synonym: "T-cell differentiation antigen L3T4 (mouse)" EXACT [UniProtKB:P06332] synonym: "T-cell surface antigen T4/Leu-3 (mouse)" EXACT [UniProtKB:P06332] xref: UniProtKB:P06332 is_a: PR:000001004 ! CD4 molecule is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000001004 ! CD4 molecule intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P06729 name: T-cell surface antigen CD2 (human) namespace: protein def: "A CD2 molecule that is encoded in the genome of human." [PRO:CNA, UniProtKB:P06729] comment: Category=organism-gene. synonym: "CD2" RELATED Gene-based [UniProtKB:P06729] synonym: "erythrocyte receptor (human)" EXACT [UniProtKB:P06729] synonym: "hCD2" EXACT PRO-short-label [PRO:DNx] synonym: "LFA-2 (human)" EXACT [UniProtKB:P06729] synonym: "LFA-3 receptor (human)" EXACT [UniProtKB:P06729] synonym: "rosette receptor (human)" EXACT [UniProtKB:P06729] synonym: "SRBC" RELATED Gene-based [UniProtKB:P06729] synonym: "T-cell surface antigen T11/Leu-5 (human)" EXACT [UniProtKB:P06729] xref: UniProtKB:P06729 is_a: PR:000001083 ! CD2 molecule is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000001083 ! CD2 molecule intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P07766 name: T-cell surface glycoprotein CD3 epsilon chain (human) namespace: protein def: "A CD3 epsilon that is encoded in the genome of human." [PRO:CNA, UniProtKB:P07766] comment: Category=organism-gene. synonym: "CD3E" RELATED Gene-based [UniProtKB:P07766] synonym: "CD3e (human)" EXACT [UniProtKB:P07766] synonym: "hCD3E" EXACT PRO-short-label [PRO:DNx] synonym: "T-cell surface antigen T3/Leu-4 epsilon chain (human)" EXACT [UniProtKB:P07766] synonym: "T3E" RELATED Gene-based [UniProtKB:P07766] xref: UniProtKB:P07766 is_a: PR:000001020 ! CD3 epsilon is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000001020 ! CD3 epsilon intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P08571 name: monocyte differentiation antigen CD14 (human) namespace: protein def: "A CD14 molecule that is encoded in the genome of human." [PRO:WCB, UniProtKB:P08571] comment: Category=organism-gene. synonym: "CD14" RELATED Gene-based [UniProtKB:P08571] synonym: "hCD14" EXACT PRO-short-label [PRO:DNx] synonym: "myeloid cell-specific leucine-rich glycoprotein (human)" EXACT [UniProtKB:P08571] xref: UniProtKB:P08571 is_a: PR:000001889 ! CD14 molecule is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000001889 ! CD14 molecule intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P08920 name: T-cell surface antigen CD2 (mouse) namespace: protein def: "A CD2 molecule that is encoded in the genome of mouse." [OMA:P08920, PRO:DNx] comment: Category=organism-gene. synonym: "Cd2" RELATED Gene-based [UniProtKB:P08920] synonym: "CD2 (mouse)" EXACT [UniProtKB:P08920] synonym: "LFA-2 (mouse)" EXACT [UniProtKB:P08920] synonym: "LFA-3 receptor (mouse)" EXACT [UniProtKB:P08920] synonym: "Ly-37" RELATED Gene-based [UniProtKB:P08920] synonym: "lymphocyte antigen 37 (mouse)" EXACT [UniProtKB:P08920] synonym: "mCD2" EXACT PRO-short-label [PRO:DNx] synonym: "T-cell surface antigen T11/Leu-5 (mouse)" EXACT [UniProtKB:P08920] xref: UniProtKB:P08920 is_a: PR:000001083 ! CD2 molecule is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000001083 ! CD2 molecule intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P10810 name: monocyte differentiation antigen CD14 (mouse) namespace: protein def: "A CD14 molecule that is encoded in the genome of mouse." [OMA:P10810, PRO:WCB] comment: Category=organism-gene. synonym: "Cd14" RELATED Gene-based [UniProtKB:P10810] synonym: "CD14 (mouse)" EXACT [UniProtKB:P10810] synonym: "mCD14" EXACT PRO-short-label [PRO:DNx] synonym: "myeloid cell-specific leucine-rich glycoprotein (mouse)" EXACT [UniProtKB:P10810] xref: UniProtKB:P10810 is_a: PR:000001889 ! CD14 molecule is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000001889 ! CD14 molecule intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P11215 name: integrin alpha-M (human) namespace: protein def: "An integrin alpha-M that is encoded in the genome of human." [PRO:DNx, UniProtKB:P11215] comment: Category=organism-gene. synonym: "CD11 antigen-like family member B (human)" EXACT [UniProtKB:P11215] synonym: "CD11B" RELATED Gene-based [UniProtKB:P11215] synonym: "cell surface glycoprotein MAC-1 subunit alpha (human)" EXACT [UniProtKB:P11215] synonym: "CR-3 alpha chain (human)" EXACT [UniProtKB:P11215] synonym: "CR3A" RELATED Gene-based [UniProtKB:P11215] synonym: "hITGAM" EXACT PRO-short-label [PRO:DNx] synonym: "ITGAM" RELATED Gene-based [UniProtKB:P11215] synonym: "leukocyte adhesion receptor MO1 (human)" EXACT [UniProtKB:P11215] synonym: "neutrophil adherence receptor (human)" EXACT [UniProtKB:P11215] xref: UniProtKB:P11215 is_a: PR:000001012 ! integrin alpha-M is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000001012 ! integrin alpha-M intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P11836 name: B-lymphocyte antigen CD20 (human) namespace: protein def: "A membrane-spanning 4-domains subfamily A member 1 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P11836] comment: Category=organism-gene. synonym: "B-lymphocyte surface antigen B1 (human)" EXACT [UniProtKB:P11836] synonym: "Bp35 (human)" EXACT [UniProtKB:P11836] synonym: "CD20" RELATED Gene-based [UniProtKB:P11836] synonym: "hMS4A1" EXACT PRO-short-label [PRO:DNx] synonym: "leukocyte surface antigen Leu-16 (human)" EXACT [UniProtKB:P11836] synonym: "membrane-spanning 4-domains subfamily A member 1 (human)" EXACT [UniProtKB:P11836] synonym: "MS4A1" RELATED Gene-based [UniProtKB:P11836] xref: UniProtKB:P11836 is_a: PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P13379 name: T-cell surface glycoprotein CD5 (mouse) namespace: protein def: "A T-cell surface glycoprotein CD5 that is encoded in the genome of mouse." [OMA:P13379, PRO:DNx] comment: Category=organism-gene. synonym: "Cd5" RELATED Gene-based [UniProtKB:P13379] synonym: "CD5 (mouse)" EXACT [UniProtKB:P13379] synonym: "Ly-1" RELATED Gene-based [UniProtKB:P13379] synonym: "lymphocyte antigen 1 (mouse)" EXACT [UniProtKB:P13379] synonym: "Lyt-1 (mouse)" EXACT [UniProtKB:P13379] synonym: "mCD5" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P13379 is_a: PR:000001839 ! T-cell surface glycoprotein CD5 is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000001839 ! T-cell surface glycoprotein CD5 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P13591 name: neural cell adhesion molecule 1 (human) namespace: protein def: "A neural cell adhesion molecule 1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P13591] comment: Category=organism-gene. synonym: "CD56 (human)" EXACT [UniProtKB:P13591] synonym: "hNCAM1" EXACT PRO-short-label [PRO:DNx] synonym: "N-CAM-1 (human)" EXACT [UniProtKB:P13591] synonym: "NCAM" RELATED Gene-based [UniProtKB:P13591] synonym: "NCAM-1 (human)" EXACT [UniProtKB:P13591] synonym: "NCAM1" RELATED Gene-based [UniProtKB:P13591] xref: UniProtKB:P13591 is_a: PR:000001024 ! neural cell adhesion molecule 1 is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000001024 ! neural cell adhesion molecule 1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P13595 name: neural cell adhesion molecule 1 (mouse) namespace: protein def: "A neural cell adhesion molecule 1 that is encoded in the genome of mouse." [OMA:P13595, PRO:DNx] comment: Category=organism-gene. synonym: "CD56 (mouse)" EXACT [UniProtKB:P13595] synonym: "mNCAM1" EXACT PRO-short-label [PRO:DNx] synonym: "N-CAM-1 (mouse)" EXACT [UniProtKB:P13595] synonym: "Ncam" RELATED Gene-based [UniProtKB:P13595] synonym: "NCAM-1 (mouse)" EXACT [UniProtKB:P13595] synonym: "Ncam1" RELATED Gene-based [UniProtKB:P13595] xref: UniProtKB:P13595 is_a: PR:000001024 ! neural cell adhesion molecule 1 is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000001024 ! neural cell adhesion molecule 1 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P15391 name: B-lymphocyte antigen CD19 (human) namespace: protein def: "A CD19 molecule that is encoded in the genome of human." [] comment: Category=organism-gene. synonym: "B-lymphocyte surface antigen B4 (human)" EXACT [UniProtKB:P15391] synonym: "CD19" RELATED Gene-based [UniProtKB:P15391] synonym: "differentiation antigen CD19 (human)" EXACT [UniProtKB:P15391] synonym: "hCD19" EXACT PRO-short-label [PRO:DNx] synonym: "T-cell surface antigen Leu-12 (human)" EXACT [UniProtKB:P15391] xref: UniProtKB:P15391 is_a: PR:000001002 ! CD19 molecule is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000001002 ! CD19 molecule intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P16871 name: interleukin-7 receptor subunit alpha (human) namespace: protein def: "An interleukin-7 receptor subunit alpha that is encoded in the genome of human." [PRO:WCB, UniProtKB:P16871] comment: Category=organism-gene. synonym: "CD127 (human)" EXACT [UniProtKB:P16871] synonym: "CDw127 (human)" EXACT [UniProtKB:P16871] synonym: "hIL7R" EXACT PRO-short-label [PRO:DNx] synonym: "IL-7 receptor subunit alpha (human)" EXACT [UniProtKB:P16871] synonym: "IL-7R subunit alpha (human)" EXACT [UniProtKB:P16871] synonym: "IL-7R-alpha (human)" EXACT [UniProtKB:P16871] synonym: "IL-7RA (human)" EXACT [UniProtKB:P16871] synonym: "IL7R" RELATED Gene-based [UniProtKB:P16871] xref: UniProtKB:P16871 is_a: PR:000001869 ! interleukin-7 receptor subunit alpha is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000001869 ! interleukin-7 receptor subunit alpha intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P16872 name: interleukin-7 receptor subunit alpha (mouse) namespace: protein def: "An interleukin-7 receptor subunit alpha that is encoded in the genome of mouse." [OMA:P16872, PRO:DNx] comment: Category=organism-gene. synonym: "CD127 (mouse)" EXACT [UniProtKB:P16872] synonym: "IL-7 receptor subunit alpha (mouse)" EXACT [UniProtKB:P16872] synonym: "IL-7R subunit alpha (mouse)" EXACT [UniProtKB:P16872] synonym: "IL-7R-alpha (mouse)" EXACT [UniProtKB:P16872] synonym: "IL-7RA (mouse)" EXACT [UniProtKB:P16872] synonym: "Il7r" RELATED Gene-based [UniProtKB:P16872] synonym: "mIL7R" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P16872 is_a: PR:000001869 ! interleukin-7 receptor subunit alpha is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000001869 ! interleukin-7 receptor subunit alpha intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P17542 name: T-cell acute lymphocytic leukemia protein 1 (human) namespace: protein def: "A T-cell acute lymphocytic leukemia protein 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P17542] comment: Category=organism-gene. synonym: "BHLHA17" RELATED Gene-based [UniProtKB:P17542] synonym: "class A basic helix-loop-helix protein 17 (human)" EXACT [UniProtKB:P17542] synonym: "hTAL1" EXACT PRO-short-label [PRO:DNx] synonym: "SCL" RELATED Gene-based [UniProtKB:P17542] synonym: "Stem cell protein (human)" EXACT [UniProtKB:P17542] synonym: "T-cell leukemia/lymphoma protein 5 (human)" EXACT [UniProtKB:P17542] synonym: "TAL-1 (human)" EXACT [UniProtKB:P17542] synonym: "TAL1" RELATED Gene-based [UniProtKB:P17542] synonym: "TCL5" RELATED Gene-based [UniProtKB:P17542] xref: Reactome:R-HSA-8956511 "PR:P17542 located_in GO:0005654" xref: UniProtKB:P17542 is_a: PR:000016043 ! T-cell acute lymphocytic leukemia protein 1 is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000016043 ! T-cell acute lymphocytic leukemia protein 1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P19437 name: B-lymphocyte antigen CD20 (mouse) namespace: protein def: "A membrane-spanning 4-domains subfamily A member 1 that is encoded in the genome of mouse." [OMA:P19437, PRO:DNx] comment: Category=organism-gene. synonym: "B-cell differentiation antigen Ly-44 (mouse)" EXACT [UniProtKB:P19437] synonym: "Cd20" RELATED Gene-based [UniProtKB:P19437] synonym: "CD20 (mouse)" EXACT [UniProtKB:P19437] synonym: "Ly-44" RELATED Gene-based [UniProtKB:P19437] synonym: "lymphocyte antigen 44 (mouse)" EXACT [UniProtKB:P19437] synonym: "membrane-spanning 4-domains subfamily A member 1 (mouse)" EXACT [UniProtKB:P19437] synonym: "mMS4A1" EXACT PRO-short-label [PRO:DNx] synonym: "Ms4a1" RELATED Gene-based [UniProtKB:P19437] synonym: "Ms4a2" RELATED Gene-based [UniProtKB:P19437] xref: UniProtKB:P19437 is_a: PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P22091 name: T-cell acute lymphocytic leukemia protein 1 homolog (mouse) namespace: protein def: "A T-cell acute lymphocytic leukemia protein 1 that is encoded in the genome of mouse." [OMA:P22091, PRO:DNx] comment: Category=organism-gene. synonym: "mTAL1" EXACT PRO-short-label [PRO:DNx] synonym: "Scl" RELATED Gene-based [UniProtKB:P22091] synonym: "Stem cell protein (mouse)" EXACT [UniProtKB:P22091] synonym: "Tal-1" RELATED Gene-based [UniProtKB:P22091] synonym: "TAL-1 (mouse)" EXACT [UniProtKB:P22091] synonym: "Tal1" RELATED Gene-based [UniProtKB:P22091] xref: UniProtKB:P22091 is_a: PR:000016043 ! T-cell acute lymphocytic leukemia protein 1 is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000016043 ! T-cell acute lymphocytic leukemia protein 1 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P22646 name: T-cell surface glycoprotein CD3 epsilon chain (mouse) namespace: protein def: "A CD3 epsilon that is encoded in the genome of mouse." [OMA:P22646, PRO:DNx] comment: Category=organism-gene. synonym: "Cd3e" RELATED Gene-based [UniProtKB:P22646] synonym: "CD3e (mouse)" EXACT [UniProtKB:P22646] synonym: "mCD3E" EXACT PRO-short-label [PRO:DNx] synonym: "T-cell surface antigen T3/Leu-4 epsilon chain (mouse)" EXACT [UniProtKB:P22646] xref: UniProtKB:P22646 is_a: PR:000001020 ! CD3 epsilon is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000001020 ! CD3 epsilon intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P25918 name: B-lymphocyte antigen CD19 (mouse) namespace: protein def: "A CD19 molecule that is encoded in the genome of mouse." [OMA:P25918, PRO:DNx] comment: Category=organism-gene. synonym: "Cd19" RELATED Gene-based [UniProtKB:P25918] synonym: "CD19 (mouse)" EXACT [UniProtKB:P25918] synonym: "differentiation antigen CD19 (mouse)" EXACT [UniProtKB:P25918] synonym: "mCD19" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P25918 is_a: PR:000001002 ! CD19 molecule is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000001002 ! CD19 molecule intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P28906 name: hematopoietic progenitor cell antigen CD34 (human) namespace: protein def: "A CD34 molecule that is encoded in the genome of human." [] comment: Category=organism-gene. synonym: "CD34" RELATED Gene-based [UniProtKB:P28906] synonym: "hCD34" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P28906 is_a: PR:000001003 ! CD34 molecule is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000001003 ! CD34 molecule intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P33151 name: cadherin-5 (human) namespace: protein def: "A cadherin-5 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P33151] comment: Category=organism-gene. synonym: "7B4 antigen (human)" EXACT [UniProtKB:P33151] synonym: "CD144 (human)" EXACT [UniProtKB:P33151] synonym: "CDH5" RELATED Gene-based [UniProtKB:P33151] synonym: "hCDH5" EXACT PRO-short-label [PRO:DNx] synonym: "vascular endothelial cadherin (human)" EXACT [UniProtKB:P33151] synonym: "VE-cadherin (human)" EXACT [UniProtKB:P33151] xref: UniProtKB:P33151 is_a: PR:000001444 ! cadherin-5 is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000001444 ! cadherin-5 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P35461 name: lymphocyte antigen 6G (mouse) namespace: protein def: "A lymphocyte antigen 6G that is encoded in the genome of mouse." [PRO:CNA, UniProtKB:P35461] comment: Category=organism-gene. synonym: "Ly-6G (mouse)" EXACT [UniProtKB:P35461] synonym: "Ly-6G.1 (mouse)" EXACT [UniProtKB:P35461] synonym: "Ly6g" RELATED Gene-based [UniProtKB:P35461] synonym: "mLy6g" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P35461 is_a: PR:000002978 ! lymphocyte antigen 6G is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000002978 ! lymphocyte antigen 6G intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P35918 name: vascular endothelial growth factor receptor 2 (mouse) namespace: protein def: "A vascular endothelial growth factor receptor 2 that is encoded in the genome of mouse." [OMA:P35918, PRO:DNx] comment: Category=organism-gene. synonym: "CD309 (mouse)" EXACT [UniProtKB:P35918] synonym: "fetal liver kinase 1 (mouse)" EXACT [UniProtKB:P35918] synonym: "Flk-1" RELATED Gene-based [UniProtKB:P35918] synonym: "FLK-1 (mouse)" EXACT [UniProtKB:P35918] synonym: "Flk1" RELATED Gene-based [UniProtKB:P35918] synonym: "Kdr" RELATED Gene-based [UniProtKB:P35918] synonym: "kinase NYK (mouse)" EXACT [UniProtKB:P35918] synonym: "mKDR" EXACT PRO-short-label [PRO:DNx] synonym: "protein-tyrosine kinase receptor flk-1 (mouse)" EXACT [UniProtKB:P35918] synonym: "VEGFR-2 (mouse)" EXACT [UniProtKB:P35918] xref: UniProtKB:P35918 is_a: PR:000002112 ! vascular endothelial growth factor receptor 2 is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000002112 ! vascular endothelial growth factor receptor 2 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P35968 name: vascular endothelial growth factor receptor 2 (human) namespace: protein def: "A vascular endothelial growth factor receptor 2 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P35968] comment: Category=organism-gene. synonym: "CD309 (human)" EXACT [UniProtKB:P35968] synonym: "fetal liver kinase 1 (human)" EXACT [UniProtKB:P35968] synonym: "FLK-1 (human)" EXACT [UniProtKB:P35968] synonym: "FLK1" RELATED Gene-based [UniProtKB:P35968] synonym: "hKDR" EXACT PRO-short-label [PRO:DNx] synonym: "KDR" RELATED Gene-based [UniProtKB:P35968] synonym: "kinase insert domain receptor (human)" EXACT [UniProtKB:P35968] synonym: "protein-tyrosine kinase receptor flk-1 (human)" EXACT [UniProtKB:P35968] synonym: "VEGFR-2 (human)" EXACT [UniProtKB:P35968] synonym: "VEGFR2" RELATED Gene-based [UniProtKB:P35968] xref: DTO:03100560 xref: UniProtKB:P35968 is_a: PR:000002112 ! vascular endothelial growth factor receptor 2 is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000002112 ! vascular endothelial growth factor receptor 2 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P37237 name: fibroblast growth factor 8 (mouse) namespace: protein def: "A fibroblast growth factor 8 that is encoded in the genome of mouse." [OMA:P37237, PRO:DNx] comment: Category=organism-gene. synonym: "Aigf" RELATED Gene-based [UniProtKB:P37237] synonym: "AIGF (mouse)" EXACT [UniProtKB:P37237] synonym: "androgen-induced growth factor (mouse)" EXACT [UniProtKB:P37237] synonym: "FGF-8 (mouse)" EXACT [UniProtKB:P37237] synonym: "Fgf8" RELATED Gene-based [UniProtKB:P37237] synonym: "HBGF-8 (mouse)" RELATED [UniProtKB:P37237] synonym: "heparin-binding growth factor 8 (mouse)" RELATED [UniProtKB:P37237] synonym: "mFGF8" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P37237 is_a: PR:000007499 ! fibroblast growth factor 8 is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000007499 ! fibroblast growth factor 8 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P55075 name: fibroblast growth factor 8 (human) namespace: protein def: "A fibroblast growth factor 8 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P55075] comment: Category=organism-gene. synonym: "AIGF" RELATED Gene-based [UniProtKB:P55075] synonym: "androgen-induced growth factor (human)" EXACT [UniProtKB:P55075] synonym: "FGF-8 (human)" EXACT [UniProtKB:P55075] synonym: "FGF8" RELATED Gene-based [UniProtKB:P55075] synonym: "HBGF-8 (human)" BROAD [UniProtKB:P55075] synonym: "heparin-binding growth factor 8 (human)" BROAD [UniProtKB:P55075] synonym: "hFGF8" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P55075 is_a: PR:000007499 ! fibroblast growth factor 8 is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000007499 ! fibroblast growth factor 8 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P55284 name: cadherin-5 (mouse) namespace: protein def: "A cadherin-5 that is encoded in the genome of mouse." [OMA:P55284, PRO:DNx] comment: Category=organism-gene. synonym: "CD144 (mouse)" EXACT [UniProtKB:P55284] synonym: "Cdh5" RELATED Gene-based [UniProtKB:P55284] synonym: "mCDH5" EXACT PRO-short-label [PRO:DNx] synonym: "vascular endothelial cadherin (mouse)" EXACT [UniProtKB:P55284] synonym: "VE-cadherin (mouse)" EXACT [UniProtKB:P55284] xref: UniProtKB:P55284 is_a: PR:000001444 ! cadherin-5 is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000001444 ! cadherin-5 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:Q15465 name: sonic hedgehog protein (human) namespace: protein def: "A sonic hedgehog protein that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q15465] comment: Category=organism-gene. synonym: "HHG-1 (human)" EXACT [UniProtKB:Q15465] synonym: "hSHH" EXACT PRO-short-label [PRO:DNx] synonym: "SHH" RELATED Gene-based [UniProtKB:Q15465] synonym: "Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains (human)" EXACT [UniProtKB:Q15465] synonym: "ShhNC (human)" EXACT [UniProtKB:Q15465] xref: UniProtKB:Q15465 is_a: PR:000014841 ! sonic hedgehog protein is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000014841 ! sonic hedgehog protein intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q62226 name: sonic hedgehog protein (mouse) namespace: protein def: "A sonic hedgehog protein that is encoded in the genome of mouse." [OMA:Q62226, PRO:DNx] comment: Category=organism-gene. synonym: "HHG-1 (mouse)" EXACT [UniProtKB:Q62226] synonym: "Hhg1" RELATED Gene-based [UniProtKB:Q62226] synonym: "mSHH" EXACT PRO-short-label [PRO:DNx] synonym: "Shh" RELATED Gene-based [UniProtKB:Q62226] synonym: "SHH (mouse)" EXACT [UniProtKB:Q62226] synonym: "Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains (mouse)" EXACT [UniProtKB:Q62226] synonym: "ShhNC (mouse)" EXACT [UniProtKB:Q62226] xref: UniProtKB:Q62226 is_a: PR:000014841 ! sonic hedgehog protein is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000014841 ! sonic hedgehog protein intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:Q62351 name: transferrin receptor protein 1 (mouse) namespace: protein def: "A transferrin receptor protein 1 that is encoded in the genome of mouse." [OMA:Q62351, PRO:DNx] comment: Category=organism-gene. synonym: "CD71 (mouse)" EXACT [UniProtKB:Q62351] synonym: "mTFRC" EXACT PRO-short-label [PRO:DNx] synonym: "TfR (mouse)" EXACT [UniProtKB:Q62351] synonym: "TfR1 (mouse)" EXACT [UniProtKB:Q62351] synonym: "Tfrc" RELATED Gene-based [UniProtKB:Q62351] synonym: "TR (mouse)" RELATED [UniProtKB:Q62351] synonym: "Trfr" RELATED Gene-based [UniProtKB:Q62351] xref: UniProtKB:Q62351 is_a: PR:000001945 ! transferrin receptor protein 1 is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000001945 ! transferrin receptor protein 1 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:Q64314 name: hematopoietic progenitor cell antigen CD34 (mouse) namespace: protein def: "A CD34 molecule that is encoded in the genome of mouse." [OMA:Q64314, PRO:DNx] comment: Category=organism-gene. synonym: "Cd34" RELATED Gene-based [UniProtKB:Q64314] synonym: "CD34 (mouse)" EXACT [UniProtKB:Q64314] synonym: "mCD34" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q64314 is_a: PR:000001003 ! CD34 molecule is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000001003 ! CD34 molecule intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:Q9V7U0 name: pro-resilin (fruit fly) namespace: protein def: "A protein that is a translation product of the resilin gene in fruit fly." [PRO:DNx, UniProtKB:Q9V7U0] comment: Category=organism-gene. synonym: "CG15920" RELATED Gene-based [UniProtKB:Q9V7U0] synonym: "fly-resilin" EXACT PRO-short-label [PRO:DNx] synonym: "resilin" RELATED Gene-based [UniProtKB:Q9V7U0] xref: UniProtKB:Q9V7U0 is_a: PR:000029060 ! Drosophila melanogaster protein intersection_of: PR:000000001 ! protein intersection_of: has_gene_template http://flybase.org/reports/FBgn0034157 ! resilin (fruit fly) intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster relationship: has_gene_template http://flybase.org/reports/FBgn0034157 ! resilin (fruit fly) [Term] id: RO:0002577 name: system def: "A material entity consisting of multiple components that are causally integrated." [] is_a: BFO:0000040 ! material entity property_value: editor_note "May be replaced by a BFO class, as discussed in http://www.jbiomedsem.com/content/4/1/43" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 "http://www.jbiomedsem.com/content/4/1/43" xsd:string [Term] id: SO:0000010 name: protein_coding namespace: sequence comment: Category=external. synonym: "protein-coding" EXACT [] is_a: BFO:0000019 ! quality [Term] id: SO:0000110 name: sequence_feature namespace: sequence def: "An extent of biological sequence." [SO:ke] synonym: "located sequence feature" RELATED [] synonym: "located_sequence_feature" EXACT [] synonym: "sequence feature" EXACT [] [Term] id: SO:0000704 name: gene namespace: sequence def: "A region (or regions) that includes all of the sequence elements necessary to encode a functional transcript. A gene may include regulatory regions, transcribed regions and/or other functional sequence regions." [SO:immuno_workshop] is_a: SO:0000110 ! sequence_feature [Term] id: SO:0001217 name: protein_coding_gene namespace: sequence synonym: "protein coding gene" EXACT [] is_a: SO:0000704 ! gene relationship: has_quality SO:0000010 ! protein_coding [Term] id: UBERON:0000000 name: processual entity namespace: uberon def: "An occurrent [span:Occurrent] that exists in time by occurring or happening, has temporal parts and always involves and depends on some entity." [span:ProcessualEntity] subset: common_anatomy subset: upper_level xref: BFO:0000003 is_a: BFO:0000003 ! occurrent disjoint_from: UBERON:0001062 ! anatomical entity property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0000005 name: chemosensory organ namespace: uberon subset: functional_classification subset: uberon_slim synonym: "chemosensory sensory organ" EXACT [FBbt:00005157] xref: FBbt:00005157 {sssom:mapping_justification="vocab:ManualMappingCuration"} is_a: UBERON:0000020 ! sense organ intersection_of: UBERON:0000020 ! sense organ intersection_of: capable_of GO:0007606 ! sensory perception of chemical stimulus relationship: capable_of GO:0007606 ! sensory perception of chemical stimulus relationship: part_of UBERON:0001016 ! nervous system relationship: part_of UBERON:0005726 ! chemosensory system [Term] id: UBERON:0000006 name: islet of Langerhans namespace: uberon def: "The clusters of hormone-producing cells that are scattered throughout the pancreas." [MA:0000127, MESH:A03.734.414, MP:0005215] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "island of Langerhans" RELATED [BTO:0000991] synonym: "island of pancreas" RELATED [BTO:0000991] synonym: "islets of Langerhans" RELATED [] synonym: "pancreatic insula" EXACT [] synonym: "pancreatic islet" EXACT [] xref: AAO:0010406 xref: BTO:0000991 xref: CALOHA:TS-0741 xref: EFO:0000856 xref: EMAPA:32927 xref: EV:0100130 xref: FMA:16016 xref: GAID:324 xref: MA:0000127 xref: MAT:0000076 xref: MESH:D007515 xref: MIAA:0000076 xref: NCIT:C12608 xref: UMLS:C0022131 {source="ncithesaurus:Islet_of_Langerhans"} xref: VHOG:0000646 xref: Wikipedia:Islets_of_Langerhans xref: XAO:0000159 is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0034922 ! cell cluster relationship: contributes_to_morphology_of UBERON:0000016 ! endocrine pancreas relationship: has_part CL:0000168 {source="PMID:16417468"} ! insulin secreting cell relationship: has_part CL:0000172 {source="PMID:16417468"} ! somatostatin secreting cell relationship: has_part CL:0000696 {gci_filler="NCBITaxon:117570", gci_relation="part_of", source="PMID:16417468"} ! PP cell relationship: has_part CL:0002067 {source="PMID:16417468"} ! type A enteroendocrine cell relationship: part_of UBERON:0000016 ! endocrine pancreas property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/9/99/Gray1105.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Anatomical structure which consists of glands developed from pancreatic ducts in the larvae and secrete insulin.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010406", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000003 "Mammals, birds, reptiles and amphibians have a pancreas with similar histology and mode of development, while in some fish, the islet cells are segregated as Brockmann bodies.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000646", ontology="VHOG", source="PMID:7600975 Slack JMW, Developmental biology of the pancreas. Development (1995)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "A primitive exocrine pancreas can be found in holocephalan cartilaginous fish; a pancreatic duct directly ending in the gut lumen is connected to a glandular structure made of exocrine cells and associated with cell islets, which comprises three different hormone-producing cell types: insulin, somatostatin and glucagon (Yui and Fujita, 1986)" xsd:string {source="PMID:16417468"} property_value: UBPROP:0000202 FMA:76489 [Term] id: UBERON:0000009 name: submucosa namespace: uberon def: "A layer of dense irregular connective tissue that lines organs and supports the mucosa, as well as joins the mucosa to the bulk of underlying smooth muscle. [WP,unvetted]." [Wikipedia:Submucosa] subset: pheno_slim subset: uberon_slim synonym: "organ submucosa" EXACT [FMA:85391] synonym: "region of submucosa" EXACT [FMA:85392] synonym: "submucosa of organ" EXACT [FMA:85391] synonym: "submucosa of region of organ" EXACT [FMA:85392] synonym: "submucous layer" RELATED [BTO:0002107] synonym: "tela submucosa" RELATED [BTO:0002107] synonym: "tunica submucosa" RELATED [] xref: BTO:0002107 xref: FMA:85391 xref: FMA:85392 xref: NCIT:C13167 xref: SCTID:68439008 xref: UMLS:C0225344 {source="ncithesaurus:Submucosa"} xref: Wikipedia:Submucosa is_a: UBERON:0004923 ! organ component layer relationship: composed_primarily_of UBERON:0002384 ! connective tissue relationship: immediately_deep_to UBERON:0000344 ! mucosa relationship: only_in_taxon NCBITaxon:7711 ! Chordata property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/4/4e/Ens.png" xsd:anyURI property_value: depiction "http://upload.wikimedia.org/wikipedia/en/thumb/4/4e/Ens.png/200px-Ens.png" xsd:anyURI property_value: UBPROP:0000007 "submucosal" xsd:string [Term] id: UBERON:0000010 name: peripheral nervous system namespace: uberon def: "A major division of the nervous system that contains nerves which connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands." [GO:0007422] subset: cumbo subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "pars peripherica" EXACT OMO:0003011 [FMA:9903, FMA:TA, Wikipedia:Peripheral_nervous_system] synonym: "PNS" BROAD OMO:0003000 [] synonym: "systema nervosum periphericum" EXACT OMO:0003011 [FMA:9903, FMA:TA, Wikipedia:Peripheral_nervous_system] xref: AAO:0000429 xref: BAMS:PNS xref: BILA:0000081 xref: BIRNLEX:1111 xref: BTO:0001028 xref: CALOHA:TS-0808 xref: EFO:0000891 xref: EHDAA2:0001445 xref: EHDAA:2893 xref: EMAPA:16665 xref: EV:0100335 xref: FBbt:00005098 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:9903 xref: GAID:715 xref: MA:0000218 xref: MAT:0000338 xref: MESH:D017933 xref: MIAA:0000338 xref: NCIT:C12465 xref: neuronames:3232 xref: SCTID:362292005 xref: TAO:0000142 xref: UMLS:C0206417 {source="ncithesaurus:Peripheral_Nervous_System", source="BIRNLEX:1111"} xref: UMLS:C1305921 {source="BIRNLEX:1111"} xref: VHOG:0000399 xref: Wikipedia:Peripheral_nervous_system xref: XAO:0000178 xref: ZFA:0000142 is_a: UBERON:0011216 {source="cjm"} ! organ system subdivision relationship: part_of UBERON:0001016 ! nervous system property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/b/ba/Nervous_system_diagram.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Nervous structures including ganglia outside of the central nervous system. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000142", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "Part of nervous system in which nerves extend throughout the body outside of the brain and spinal cord.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000429", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "The peripheral nervous system (PNS) is the part of the nervous system connected to the CNS which contains cranial nerves III - XII, spinal, peripheral and autonomic nerves. (CUMBO)" xsd:string {source="http://neurolex.org/wiki/Cumbo_terms"} property_value: UBPROP:0000003 "(...) specific vertebrate traits within the chordate phylum such as skeletal tissues, PNS, and spectacular head and brain development, are linked to the NC (neural crest) and its derivatives.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000399", ontology="VHOG", source="DOI:10.1007/978-0-387-46954-6_6 Dupin E, Creuzet S, Le Douarin NM, The contribution of the neural crest to the vertebrate body. Advances in experimental medicine and biology (2006)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0000013 name: sympathetic nervous system namespace: uberon def: "The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter [GO]." [GO:0048485] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "pars sympathica divisionis autonomici systematis nervosi" EXACT OMO:0003011 [FMA:9906, FMA:TA] synonym: "pars sympathica divisionis autonomici systematis nervosi" RELATED OMO:0003011 [Wikipedia:Sympathetic_nervous_system] synonym: "sympathetic nervous system" EXACT [] synonym: "sympathetic part of autonomic division of nervous system" EXACT [] xref: AAO:0010487 xref: BIRNLEX:2516 xref: BTO:0001832 xref: CALOHA:TS-2050 xref: EFO:0000893 xref: EHDAA2:0001971 xref: EHDAA:3769 xref: EMAPA:16985 xref: FMA:9906 xref: GAID:710 xref: MA:0000225 xref: MESH:D013564 xref: MIAA:0000100 xref: NCIT:C12795 xref: SCTID:362484004 xref: TAO:0001576 xref: UMLS:C0039044 {source="BIRNLEX:2516", source="ncithesaurus:Sympathetic_Nervous_System"} xref: UMLS:C1269646 {source="BIRNLEX:2516"} xref: VHOG:0000384 xref: Wikipedia:Sympathetic_nervous_system xref: ZFA:0001576 is_a: UBERON:0011216 {source="cjm"} ! organ system subdivision relationship: contributes_to_morphology_of UBERON:0002410 ! autonomic nervous system relationship: part_of UBERON:0002410 {source="FMA", source="MA", source="ZFA-modified-from-isa"} ! autonomic nervous system property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/7/77/Gray838.png" xsd:anyURI property_value: UBPROP:0000001 "Part of the autonomic nervous system which has opposing physiological effects of the parasympathetic nervous system. Examples include increasing the heart rate or constricting the blood vessels.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010487", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "The part of the autonomic nervous system which chiefly contains adrenergic fibres and tends to control and reduce secretions, decrease the contractility and hence the tone of smooth muscles and provoke the contraction of blood vessels. Essentially, it consists of preganglionic fibres from the thoracic and upper lumbar parts of the spinal cord. These fibres, by means of delicate rami communicantes, cross over to ganglia sited in a pair of ganglionated cords on each side of the vertebral column or to more peripheral ganglia. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000384", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "The autonomic nervous system is composed of three divisions: the sympathetic division, the parasympathetic division, and the enteric division. (...) In ray-finned teleost fishes, a sympathetic chain is present, and dual innervation of additional organs can be observed. A similar pattern can be found in amphibians (...). The evolution of the autonomic nervous system has been quite conservative, especially in the tetrapod lineage.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000384", ontology="VHOG", source="ISBN:978-0471210054 Butler AB and Hodos W, Comparative vertebrate neuroanatomy: Evolution and Adaptation (2005) p.461-463", source="http://bgee.unil.ch/"} property_value: UBPROP:0000011 "has developmental contribution from NC in verteberates (https://github.com/obophenotype/uberon/wiki/The-neural-crest)" xsd:string [Term] id: UBERON:0000014 name: zone of skin namespace: uberon def: "Any portion of the organ that covers that body and consists of a layer of epidermis and a layer of dermis." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Skin] subset: pheno_slim synonym: "portion of skin" EXACT [] synonym: "region of skin" EXACT [] synonym: "skin" EXACT [MA:0000151] synonym: "skin region" EXACT [] synonym: "skin zone" EXACT [] xref: EHDAA2:0001844 xref: EHDAA:6530 xref: EMAPA:17525 xref: EV:0100152 xref: FMA:86166 xref: GAID:933 xref: MA:0000151 xref: MAT:0000284 xref: MESH:D012867 xref: MIAA:0000284 xref: SCTID:20795001 xref: VHOG:0000860 xref: Wikipedia:Skin is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0010314 ! structure with developmental contribution from neural crest is_a: UBERON:0034944 {source="FMA"} ! zone of organ relationship: has_part UBERON:0001003 ! skin epidermis relationship: has_part UBERON:0002067 ! dermis relationship: part_of UBERON:0002097 ! skin of body property_value: curator_notes "Note the distinction between the entire skin of the body, of which there is only 1 in an organism, and zones of skin, of which there can be many. Examples: skin of knee" xsd:string property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/6/6d/Skin.svg" xsd:anyURI property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/e/e8/HumanSkinDiagram.jpg" xsd:anyURI property_value: UBPROP:0000003 "(...) it is well-established that neural crest cells contribute to both the dermal skeleton (craniofacial bone, teeth, and the caudal fin rays of teleosts) and the integument, including craniofacial dermis and all pigment cells outside the retina (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000860", ontology="VHOG", source="DOI:10.1111/j.1469-7580.2008.01043.x Vickaryous MK, Sire JY, The integumentary skeleton of tetrapods: origin, evolution, and development. J Anat (2009)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "we assume that mouse, HOG and GAID all mean zone of skin when they say skin. We also choose skin as an exact synonym, as it is more intuitive" xsd:string [Term] id: UBERON:0000015 name: non-material anatomical boundary namespace: uberon def: "A non-material anatomical entity of two dimensions. Anatomical boundaries are contiguous structures." [CARO:0000010] comment: Except in the case of abstracted fiat boundaries such as the midline plane of an organism, all 2D anatomical entities have a 3 dimensional projection. For example, the surface of the shell of a muscle has a distinct shape that projects into the third dimension. Note that boundaries are 2D structures. They have no thickness - and so can not be sites of gene expression or gene product localisation. For this, use boundary region terms. subset: common_anatomy subset: upper_level synonym: "anatomical boundary" EXACT [CARO:0000010] xref: AEO:0000192 xref: CARO:0000010 xref: FMA:50705 is_a: UBERON:0000466 {source="CARO"} ! immaterial anatomical entity property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0000016 name: endocrine pancreas namespace: uberon def: "The part of the pancreas that is part of the endocrine system and is made up of islet cells, which produce insulin, glucagon and somatostatin." [GO:GO, http://orcid.org/0000-0002-6601-2165] subset: efo_slim subset: human_reference_atlas subset: organ_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "endocrine pancreas" EXACT [] synonym: "endocrine part of pancreas" RELATED [BTO:0000650] synonym: "islets of Langerhans part of pancreas" RELATED [] synonym: "pars endocrina pancreatis" EXACT [] xref: BTO:0000650 xref: CALOHA:TS-1302 xref: EFO:0002542 xref: EMAPA:35305 xref: EV:0100129 xref: FMA:16018 xref: MA:0001582 xref: MESH:D007515 {sssom:mapping_provider="https://github.com/biopragmatics/biomappings", sssom:mapping_justification="vocab:LexicalMatching"} xref: NCIT:C32509 xref: SCTID:361339003 xref: TAO:0001260 xref: VHOG:0000049 xref: Wikipedia:Islets_of_Langerhans xref: ZFA:0001260 is_a: UBERON:0000471 {source="ZFA"} ! compound organ component is_a: UBERON:0004119 ! endoderm-derived structure relationship: capable_of GO:0030073 {source="GO"} ! insulin secretion relationship: capable_of GO:0070091 {source="GO"} ! glucagon secretion relationship: capable_of GO:0070253 {source="GO"} ! somatostatin secretion relationship: composed_primarily_of UBERON:0000006 ! islet of Langerhans relationship: contributes_to_morphology_of UBERON:0001264 ! pancreas relationship: develops_from UBERON:0003923 ! dorsal pancreatic bud relationship: part_of NCBITaxon:6072 ! Eumetazoa relationship: part_of UBERON:0000949 {source="AAO", source="FMA", source="XAO"} ! endocrine system relationship: part_of UBERON:0001264 ! pancreas property_value: editor_note "create a separate class for distributed pancreas, eg cyclostomes?" xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "The part of the pancreas that acts as an endocrine gland, consisting of the islets of Langerhans, which secrete insulin and other hormones. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000049", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/Pancreas"} property_value: UBPROP:0000001 "The zebrafish endocrine pancreas is composed of small groups of islet cells that are distributed throughout the exocrine pancreas. The islet cells produce insulin, glucagon and somatostatin.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001260", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "In the hagfish and lampreys (our most primitive vertebrate species of today), the first sign of 'a new organ' is found as collections of endocrine cells around the area of the bile duct connection with the duodenum. These endocrine organs are composed of 99% beta cells and 1% somatostatin-producing delta cells. Compared to the more primitive protochordates (e.g. amphioxus), this represents a stage where all previously scattered insulin-producing cells of the intestinal tissue have now quantitatively migrated to found a new organ involved in sensing blood glucose rather than gut glucose. Only later in evolution, the beta cells are joined by exocrine tissue and alpha cells (exemplified by the rat-, rabbit- and elephant-fishes). Finally, from sharks and onwards in evolution, we have the islet PP-cell entering to complete the pancreas.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000049", ontology="VHOG", source="DOI:10.1016/j.crvi.2007.03.006 Madsen OD, Pancreas phylogeny and ontogeny in relation to a 'pancreatic stem cell'. C.R. Biologies (2007)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "endocrine and exocrine pancreas are not co-associated in hagfishes or lampreys" xsd:string {source="PMID:20959416"} [Term] id: UBERON:0000017 name: exocrine pancreas namespace: uberon def: "The part of the pancreas that is part of the exocrine system and which produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells [GO]." [GOC:GO, http://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas subset: organ_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "exocrine component of pancreas" RELATED [] synonym: "exocrine pancreas" EXACT [] synonym: "exocrine part of pancreas" RELATED [BTO:0000434] synonym: "pars exocrina pancreatis" EXACT [] xref: AAO:0010407 xref: BTO:0000434 xref: CALOHA:TS-1241 xref: EMAPA:35328 xref: EV:0100093 xref: FMA:16017 xref: MA:0002415 xref: MESH:D046790 {sssom:mapping_justification="vocab:ManualMappingCuration", sssom:author_id="https://orcid.org/0000-0001-9439-5346", sssom:mapping_provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C32546 xref: SCTID:248202004 xref: TAO:0001249 xref: UMLS:C0553695 {source="ncithesaurus:Exocrine_Pancreas"} xref: VHOG:0000048 xref: Wikipedia:Exocrine_component_of_pancreas xref: XAO:0000137 xref: ZFA:0001249 is_a: UBERON:0000409 ! serous gland is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0005177 ! trunk region element relationship: capable_of_part_of GO:0007586 ! digestion relationship: contributes_to_morphology_of UBERON:0001264 ! pancreas relationship: develops_from UBERON:0003924 ! ventral pancreatic bud relationship: has_part UBERON:0001263 ! pancreatic acinus relationship: has_part UBERON:0007329 ! pancreatic duct relationship: part_of UBERON:0001264 ! pancreas property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "The exocrine pancreas is composed of acinar epithelial cells and ductal epithelium that manufacture the proteolytic enzymes and bicarbonate required for digestion.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001249", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "The part of the pancreas that acts as an exocrine gland, consisting of the pancreatic acini, which produce pancreatic juice and secrete it into the intestine to aid in protein digestion. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000048", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/Pancreas"} property_value: UBPROP:0000003 "In the hagfish and lampreys (our most primitive vertebrate species of today), the first sign of 'a new organ' is found as collections of endocrine cells around the area of the bile duct connection with the duodenum. These endocrine organs are composed of 99% beta cells and 1% somatostatin-producing delta cells. Compared to the more primitive protochordates (e.g. amphioxus), this represents a stage where all previously scattered insulin-producing cells of the intestinal tissue have now quantitatively migrated to found a new organ involved in sensing blood glucose rather than gut glucose. Only later in evolution, the beta cells are joined by exocrine tissue and alpha cells (exemplified by the rat-, rabbit- and elephant-fishes). Finally, from sharks and onwards in evolution, we have the islet PP-cell entering to complete the pancreas.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000048", ontology="VHOG", source="DOI:10.1016/j.crvi.2007.03.006 Madsen OD, Pancreas phylogeny and ontogeny in relation to a 'pancreatic stem cell'. C.R. Biologies (2007)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0000018 name: compound eye namespace: uberon def: "A light sensing organ composed of ommatidia." [FB:gg, Wikipedia:Compound_eye] subset: organ_slim subset: uberon_slim synonym: "adult compound eye" RELATED [] synonym: "faceted eye" RELATED [] synonym: "Facettenauge" RELATED [BTO:0001921] synonym: "insect eye" RELATED [] synonym: "Komplexauge" RELATED [BTO:0001921] synonym: "zusammengesetztes Auge" RELATED [BTO:0001921] xref: BTO:0001921 xref: FBbt:00004508 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: HAO:0000217 xref: IDOMAL:0002421 {sssom:mapping_justification="vocab:ManualMappingCuration", sssom:author_id="https://orcid.org/0000-0003-4423-4370", sssom:mapping_provider="https://github.com/biopragmatics/biomappings"} xref: TGMA:0000024 xref: Wikipedia:Compound_eye is_a: UBERON:0015165 ! multi-unit eye intersection_of: UBERON:0000970 ! eye intersection_of: composed_primarily_of UBERON:0000971 ! ommatidium relationship: composed_primarily_of UBERON:0000971 ! ommatidium relationship: only_in_taxon NCBITaxon:6656 {source="PMID:21062451"} ! Arthropoda property_value: seeAlso "https://github.com/obophenotype/uberon/issues/457" xsd:anyURI property_value: UBPROP:0000008 "The term compound eye is sometimes used for the multi-unit eyes of annelids, bivalves, echinoderms. We follow Richter et al and restrict this class to the arthropod structure for these structures" xsd:string {source="PMID:21062451"} [Term] id: UBERON:0000019 name: camera-type eye namespace: uberon def: "An organ of sight that includes the camera-type eyeball and supporting structures such as the lacrimal apparatus, the conjunctiva, the eyelid." [GO:0043010, https://orcid.org/0000-0002-6601-2165] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "camera-type eye plus associated structures" RELATED [] synonym: "eye" BROAD [FMA:54448] synonym: "eyes" RELATED OMO:0003004 [TAO:0000107] synonym: "orbital part of face" RELATED [FMA:54448] synonym: "orbital region" RELATED [FMA:54448] synonym: "regio orbitalis" EXACT OMO:0003011 [FMA:54448, FMA:TA] synonym: "vertebrate eye" NARROW [] xref: AAO:0010340 xref: BIRNLEX:1169 xref: BTO:0004688 xref: EHDAA2:0000484 xref: EHDAA:936 xref: EMAPA:16198 xref: FMA:54448 xref: MA:0000261 xref: NCIT:C12401 xref: SCTID:181143004 xref: TAO:0000107 xref: UMLS:C0015392 {source="BIRNLEX:1169", source="ncithesaurus:Eye"} xref: UMLS:C1280202 {source="BIRNLEX:1169"} xref: VHOG:0000275 xref: XAO:0000179 xref: ZFA:0000107 is_a: UBERON:0000047 ! simple eye is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0010314 ! structure with developmental contribution from neural crest is_a: UBERON:0015212 ! lateral structure relationship: develops_from UBERON:0003072 {evidence="definitional"} ! optic cup relationship: existence_ends_during UBERON:0000066 ! fully formed stage relationship: has_part UBERON:0000965 ! lens of camera-type eye relationship: has_part UBERON:0000966 ! retina relationship: in_lateral_side_of UBERON:0000033 ! head relationship: part_of UBERON:0004088 ! orbital region property_value: UBPROP:0000001 "A cavitated compound organ that transduces light waves into neural signals.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000107", ontology="TAO", source="TAO:wd"} property_value: UBPROP:0000003 "The eye of the adult lamprey is remarkably similar to our own, and it possesses numerous features (including the expression of opsin genes) that are very similar to those of the eyes of jawed vertebrates. The lamprey's camera-like eye has a lens, an iris and extra-ocular muscles (five of them, unlike the eyes of jawed vertebrates, which have six), although it lacks intra-ocular muscles. Its retina also has a structure very similar to that of the retinas of other vertebrates, with three nuclear layers comprised of the cell bodies of photoreceptors and bipolar, horizontal, amacrine and ganglion cells. The southern hemisphere lamprey, Geotria australis, possesses five morphological classes of retinal photoreceptor and five classes of opsin, each of which is closely related to the opsins of jawed vertebrates. Given these similarities, we reach the inescapable conclusion that the last common ancestor of jawless and jawed vertebrates already possessed an eye that was comparable to that of extant lampreys and gnathostomes. Accordingly, a vertebrate camera-like eye must have been present by the time that lampreys and gnathostomes diverged, around 500 Mya.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000275", ontology="VHOG", source="DOI:10.1038/nrn2283 Lamb TD, Collin SP and Pugh EN Jr, Evolution of the vertebrate eye: opsins, photoreceptors, retina and eye cup. Nature Reviews Neuroscience (2007)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "FMA distinguishes Eye (subdivision of face) which has its parts an Eyeball (organ), as well as other structures, and the orbit of skull. MA includes eyelid, conjunctiva and lacrimal apparatus as part of MA:eye - consistent with FMA - so we can infer that MA:eye is more like FMA:eye than FMA:eyeball. For other AOs this distinction is less meaningful - e.g. ZFA has no eyelid; XAO has no eyelid, but it has conjuctiva, which is considered part of the xao:eye. GO considers eyelid development part of eye development. See also notes on optic nerve - XAO, AAO and BTO consider this part of the eye. MA considers the eye muscles part of the eye, whereas FMA has a class 'orbital content' for this" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0000020 name: sense organ namespace: uberon def: "An organ that is capable of transducing sensory stimulus to the nervous system." [https://github.com/obophenotype/uberon/issues/549, https://orcid.org/0000-0002-6601-2165] subset: uberon_slim synonym: "organ of sense organ system" EXACT [OBOL:accepted] synonym: "organ of sensory organ system" EXACT [OBOL:accepted] synonym: "organ of sensory system" EXACT [OBOL:accepted] synonym: "sense organ system organ" EXACT [OBOL:automatic] synonym: "sensillum" NARROW [WBbt:0006929] synonym: "sensor" RELATED [] synonym: "sensory organ" EXACT [] synonym: "sensory organ system organ" EXACT [OBOL:automatic] synonym: "sensory system organ" EXACT [OBOL:accepted] synonym: "Sinnesorgan" RELATED [BTO:0000202] xref: AEO:0000094 xref: BSA:0000121 xref: BTO:0000202 xref: CALOHA:TS-2043 xref: EHDAA2:0001824 xref: EHDAA:500 xref: EMAPA:35955 xref: FBbt:00005155 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: GAID:63 xref: HAO:0000930 xref: MA:0000017 xref: MESH:D012679 xref: NCIT:C33224 xref: SCTID:244485009 xref: UMLS:C0935626 {source="ncithesaurus:Organ_of_the_Special_Sense"} xref: VHOG:0001407 xref: WBbt:0006929 is_a: UBERON:0000062 ! organ intersection_of: UBERON:0000062 ! organ intersection_of: capable_of GO:0050906 ! detection of stimulus involved in sensory perception relationship: capable_of GO:0050906 ! detection of stimulus involved in sensory perception relationship: part_of UBERON:0001032 ! sensory system property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/c/c0/Gray722.png" xsd:anyURI property_value: x_1.1:contributor https://github.com/cmungall [Term] id: UBERON:0000025 name: tube namespace: uberon def: "Any hollow cylindrical anatomical structure containing a lumen through which substances are transported." [http://orcid.org/0000-0002-6601-2165] synonym: "anatomical tube" EXACT [] synonym: "duct" NARROW [] xref: galen:Tube is_a: UBERON:0004111 ! anatomical conduit intersection_of: UBERON:0004111 ! anatomical conduit intersection_of: has_quality PATO:0002299 ! tubular relationship: has_part UBERON:0013522 ! subdivision of tube relationship: has_quality PATO:0002299 ! tubular property_value: curator_notes "not every anatomical conduit is a tube - for example, a bone foramen is an opening in the bone, and there is no distinct separate tube structure. Tubes may transport large mixed objects (for example, a bolus of food in the digestive tube) or they may transport the secretions of a single gland (for example, gland ducts)" xsd:string property_value: UBPROP:0000007 "tubular" xsd:string [Term] id: UBERON:0000026 name: appendage namespace: uberon def: "Major subdivision of an organism that protrudes from the body[DOS, CARO]." [CARO:DOS] subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "appendages" RELATED OMO:0003004 [XAO:0000218] synonym: "extremitaet" RELATED [BTO:0001492] synonym: "extremity" RELATED [] synonym: "limbs/digits/tail" RELATED [MP:0000001] xref: AEO:0000193 xref: BILA:0000018 xref: BTO:0001492 xref: CARO:0010003 xref: EFO:0000799 xref: EHDAA2:0003193 xref: EMAPA:37283 {source="MA:th"} xref: EV:0100155 xref: FBbt:00007000 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: HAO:0000144 xref: MAT:0000023 xref: MESH:D005121 xref: MIAA:0000023 xref: NCIT:C61460 xref: UMLS:C0598782 {source="ncithesaurus:Appendage"} xref: VSAO:0000075 xref: Wikipedia:Appendage xref: XAO:0000218 is_a: UBERON:0000475 ! organism subdivision relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa property_value: UBPROP:0000001 "An appendage is an external body part, or natural prolongation, that protrudes from an organism's body, such as a vertebrate's limbs[BILA][BILA:0000018]." xsd:string {source="BILA:0000018"} property_value: UBPROP:0000001 "Organ or organ part that is attached to the body of an organism. For example a limb[GO, modified][GO:0048736]." xsd:string {source="GO:0048736"} property_value: UBPROP:0000007 "appendicular" xsd:string property_value: UBPROP:0000008 "this is currently a subtype of organism subdivision - which would exclude feathers" xsd:string [Term] id: UBERON:0000030 name: lamina propria namespace: uberon def: "A thin layer of loose connective tissue which lies beneath the epithelium and together with the epithelium constitutes the mucosa[WP]. The lamina propria contains capillaries and a central lacteal (lymph vessel) in the small intestine, as well as lymphoid tissue. Lamina propria also contains glands with the ducts opening on to the mucosal epithelium, that secrete mucus and serous secretions." [Wikipedia:Lamina_propria] subset: uberon_slim synonym: "lamina propria mucosa" EXACT [] synonym: "lamina propria mucosae" EXACT [] synonym: "tunica propria" RELATED [BTO:0002330] xref: BTO:0002330 xref: FMA:62517 xref: NCIT:C32918 xref: SCTID:298225002 xref: UMLS:C1179187 {source="ncithesaurus:Lamina_Propria"} xref: Wikipedia:Lamina_propria is_a: UBERON:0004923 ! organ component layer relationship: composed_primarily_of UBERON:0011825 ! loose connective tissue relationship: immediately_deep_to UBERON:0000483 ! epithelium relationship: part_of UBERON:0000344 ! mucosa property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/f/fb/GI_Organization.svg" xsd:anyURI [Term] id: UBERON:0000031 name: lamina propria of trachea namespace: uberon def: "A lamina propria that is part of a respiratory airway." [OBOL:automatic] synonym: "lamina propria mucosa of trachea" EXACT [OBOL:automatic] synonym: "lamina propria mucosa of windpipe" EXACT [OBOL:automatic] synonym: "lamina propria mucosae of trachea" EXACT [OBOL:automatic] synonym: "lamina propria mucosae of windpipe" EXACT [OBOL:automatic] synonym: "lamina propria of windpipe" EXACT [OBOL:automatic] synonym: "trachea lamina propria" EXACT [] synonym: "trachea lamina propria mucosa" EXACT [OBOL:automatic] synonym: "trachea lamina propria mucosae" EXACT [OBOL:automatic] synonym: "tracheal lamina propria" EXACT [] synonym: "windpipe lamina propria" EXACT [OBOL:automatic] synonym: "windpipe lamina propria mucosa" EXACT [OBOL:automatic] synonym: "windpipe lamina propria mucosae" EXACT [OBOL:automatic] xref: EMAPA:35877 xref: FMA:265157 xref: MA:0001858 xref: NCIT:C49305 xref: UMLS:C1710457 {source="ncithesaurus:Trachea_Lamina_Propria"} is_a: UBERON:0004779 ! respiratory system lamina propria intersection_of: UBERON:0000030 ! lamina propria intersection_of: part_of UBERON:0001005 ! respiratory airway relationship: part_of UBERON:0000379 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! tracheal mucosa [Term] id: UBERON:0000033 name: head namespace: uberon def: "The head is the anterior-most division of the body [GO]." [GO:0060322, Wikipedia:Head] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "adult head" NARROW [] synonym: "cephalic area" RELATED [SPD:0000016] synonym: "head (volume)" EXACT [FMA:7154] xref: AAO:0010335 xref: AEO:0000106 xref: BILA:0000115 xref: BIRNLEX:1230 xref: BTO:0000282 xref: CALOHA:TS-0436 xref: EFO:0000964 xref: EHDAA2:0003106 xref: EMAPA:31858 xref: FMA:7154 xref: GAID:61 xref: galen:Head xref: HAO:0000397 xref: MA:0000023 xref: MAT:0000294 xref: MESH:D006257 xref: MIAA:0000294 xref: NCIT:C12419 xref: SCTID:302548004 xref: SPD:0000016 xref: TAO:0001114 xref: TGMA:0000002 xref: UMLS:C0018670 {source="ncithesaurus:Head", source="BIRNLEX:1230"} xref: VHOG:0001644 xref: WBbt:0005739 xref: Wikipedia:Head xref: XAO:0003024 xref: ZFA:0001114 is_a: UBERON:0011676 ! subdivision of organism along main body axis relationship: has_skeleton UBERON:0003129 {gci_relation="part_of", gci_filler="NCBITaxon:7776"} ! skull relationship: only_in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of UBERON:0007811 ! craniocervical region property_value: RO:0002171 UBERON:0000948 property_value: UBPROP:0000001 "Organism subdivision that is the part of the body consisting of the cranial and pharyngeal regions.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010335", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "Organism subdivision which is the part of the body which consists of the cranial and pharygeal regions.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001114", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "Vertebrate evolution has been characterized by a fresh and vast array of cranial structures that collectively form the head.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001644", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.82", source="http://bgee.unil.ch/"} [Term] id: UBERON:0000042 name: serous membrane namespace: uberon def: "Multi-tissue structure that is comprised of a secretory epithelial layer (mesothelium) and a connective tissue layer." [https://github.com/obophenotype/uberon/issues/86, Wikipedia:Serous_membrane] subset: uberon_slim subset: vertebrate_core synonym: "serosa" RELATED [Wikipedia:Serous_membrane] synonym: "tunica serosa" EXACT OMO:0003011 [FMA:9581] synonym: "wall of serous sac" EXACT [FMA:9581] xref: FMA:9581 xref: GAID:19 xref: MESH:D012704 xref: NCIT:C13169 xref: SCTID:362878009 xref: TAO:0005425 xref: UMLS:C0036760 {source="ncithesaurus:Serosa"} xref: Wikipedia:Serous_membrane xref: ZFA:0005425 is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000481 ! multi-tissue structure is_a: UBERON:0004120 ! mesoderm-derived structure relationship: has_part UBERON:0001136 ! mesothelium relationship: has_part UBERON:0002384 ! connective tissue relationship: part_of NCBITaxon:6072 ! Eumetazoa relationship: part_of UBERON:0000060 ! anatomical wall property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/4/4e/Ens.png" xsd:anyURI property_value: depiction "http://upload.wikimedia.org/wikipedia/en/thumb/4/4e/Ens.png/200px-Ens.png" xsd:anyURI property_value: UBPROP:0000001 "A multi-tissue structure that is comprised of a secretory epithelial layer and a connective tissue layer.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005425", ontology="TAO", source="Wikipedia:Serous_membrane"} property_value: UBPROP:0000001 "a smooth membrane consisting of a thin layer of cells which excrete serous fluid. Serous membranes line and enclose several body cavities, known as serous cavities, where they secrete a lubricating fluid which reduces friction from muscle movement. Serosa is not to be confused with adventitia, a connective tissue layer which binds together structures rather than reducing friction between them. Each serous membrane is composed of a secretory epithelial layer and a connective tissue layer underneath. The epithelial layer, known as mesothelium, consists of a single layer of avascular flat nucleated cells (cuboidal epithelium) which produce the lubricating serous fluid. This fluid has a consistency similar to thin mucus. These cells are bound tightly to the underlying connective tissue. The connective tissue layer provides the blood vessels and nerves for the overlying secretory cells, and also serves as the binding layer which allows the whole serous membrane to adhere to organs and other structures.[WP]" xsd:string {source="Wikipedia:Serous_membrane"} property_value: UBPROP:0000012 "in FMA, SM = mesothelium + connective tissue. It excludes the cavity. Serous sac = SM + cavity. Note that the SM is a subtype of wall in FMA." xsd:string {external_ontology="FMA"} property_value: x_1.1:contributor https://github.com/cmungall [Term] id: UBERON:0000043 name: tendon namespace: uberon def: "Dense regular connective tissue that connects muscle to bone[VSAO]." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, VSAO:0000073, Wikipedia:Tendon] subset: pheno_slim subset: uberon_slim synonym: "sinew" RELATED [Wikipedia:Tendon] synonym: "tendo" RELATED OMO:0003011 [Wikipedia:Tendon] xref: AEO:0000091 xref: BTO:0001356 xref: CALOHA:TS-1021 xref: EHDAA2:0003091 xref: EMAPA:35854 xref: EV:0100149 xref: FMA:9721 xref: GAID:276 xref: galen:Tendon xref: MA:0000115 xref: MESH:D013710 xref: NCIT:C13045 xref: SCTID:256667004 xref: UMLS:C0039508 {source="ncithesaurus:Tendon"} xref: VHOG:0001286 xref: VSAO:0000073 xref: Wikipedia:Tendon xref: XAO:0000173 xref: ZFA:0005647 is_a: UBERON:0007846 {source="VSAO"} ! dense regular connective tissue relationship: connects UBERON:0001474 ! bone element relationship: connects UBERON:0001630 ! muscle organ relationship: has_part CL:0000327 {source="AEO"} ! extracellular matrix secreting cell relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0002204 {source="OG"} ! musculoskeletal system property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/3/3c/Achilles-tendon.jpg" xsd:anyURI property_value: UBPROP:0000001 "Dense regular connective tissue that connects muscle to bone.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000073", ontology="VSAO", source="PSPUB:0000170"} property_value: UBPROP:0000003 "Phylogenetically, tendinous tissue first appears in the invertebrate chordate Branchiostoma as myosepta. This two-dimensional array of collagen fibers is highly organized, with fibers running along two primary axes. In hagfish the first linear tendons appear and the myosepta have developed specialized regions with unidirectional fiber orientation - a linear tendon within the flat sheet of myoseptum.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001286", ontology="VHOG", source="DOI:10.1016/S1095-6433(02)00241-6 Summers AP, Koob TJ, The evolution of tendon - morphology and material properties. Comparative Biochemistry and Physiology-Part A: Molecular and Integrative Physiology (2002)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "in FMA, tendon is an organ component that with parts dense-irregular-connective-tissue of tendon and dense-irregular-connective-tissue of tendon sheath; we follow VSAO in making it a subtype of the former. In VSAO tendons connect muscle to bone; in WP the def states integument (e.g. auricular muscles) - but JB confirms this is not actually tendon but aponeurosis" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0000045 name: ganglion namespace: uberon def: "A biological tissue mass, most commonly a mass of nerve cell bodies." [https://github.com/obophenotype/uberon/issues/300, Wikipedia:Ganglion] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "ganglia" RELATED [] synonym: "neural ganglion" RELATED [BTO:0000497] xref: AAO:0010426 xref: AEO:0000135 xref: BAMS:G xref: BTO:0000497 xref: CALOHA:TS-0397 xref: EFO:0000899 xref: EHDAA2:0003135 xref: EHDAA:2897 xref: EHDAA:4662 xref: EHDAA:5621 xref: EHDAA:918 xref: EMAPA:32846 xref: EV:0100372 xref: FMA:5884 xref: MA:0002406 xref: MAT:0000207 xref: MAT:0000343 xref: MESH:D005724 xref: MIAA:0000207 xref: MIAA:0000343 xref: NCIT:C12719 xref: NLXANAT:100302 xref: TAO:0000190 xref: TGMA:0001016 xref: UMLS:C0017067 {source="ncithesaurus:Ganglion"} xref: VHOG:0000156 xref: WBbt:0005189 xref: Wikipedia:Ganglion xref: XAO:0000209 xref: ZFA:0000190 is_a: UBERON:0000061 {source="https://github.com/obophenotype/uberon/issues/2495#issuecomment-1187364719"} ! anatomical structure relationship: composed_primarily_of UBERON:0003714 {source="EHDAA2"} ! neural tissue relationship: develops_from UBERON:0003869 ! presumptive ganglion relationship: immediate_transformation_of UBERON:0003869 {source="Bgee:AN"} ! presumptive ganglion relationship: part_of UBERON:0001016 ! nervous system property_value: editor_note "TODO - check vert vs invert. Other species: Any of a number of aggregations of neurons, glial cells and their processes, surrounded by a glial cell and connective tissue sheath (plural: ganglia). // Subdivision of neural tree (organ) which primarily consists of cell bodies of neurons located outside the neuraxis (brain and spinal cord); together with a nucleus and its associated nerve, it constitutes a neural tree (organ). Examples: spinal ganglion, trigeminal ganglion, superior cervical ganglion, celiac ganglion, inferior hypogastric (pelvic) ganglion. // a cluster of nerve cells and associated glial cells (nuclear location) // Portion of tissue that contains cell bodies of neurons and is located outside the central nervous system." xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "A ganglion is a cluster of neurons. It is part of a nervous system. It may include glial cells. The neurons are arranged in a specific constellation: neuronal somata are concentrated at the surface, thus forming a cell cortex, and neurites are concentrated in the centre of the ganglion to form the neuropil. A ganglion is a distinct unit but several ganglia may be anterio-posteriorly joined by connectives or transversally by commissures" xsd:string {source="PMID:21062451"} property_value: UBPROP:0000001 "Portion of tissue that contains cell bodies of neurons and is located outside the central nervous system.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010426", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000001 "Structures containing a collection of nerve cell bodies. (Source: BioGlossary, www.Biology-Text.com)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000190", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "Subdivision of nervous system which primarily consists of cell bodies of neurons located outside the neuraxis (brain and spinal cord. Examples: spinal ganglion, trigeminal ganglion, superior cervical ganglion, celiac ganglion, inferior hypogastric (pelvic) ganglion (adapted from Foundational Model of Anatomy)[NLXANAT:100302]." xsd:string {source="NLXANAT:100302"} property_value: UBPROP:0000003 "Cranial sensory placodes are focused areas of the head ectoderm of vertebrates that contribute to the development of the cranial sense organs and their associated ganglia. Placodes have long been considered a key character of vertebrates, and their evolution is proposed to have been essential for the evolution of an active predatory lifestyle by early vertebrates.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000156", ontology="VHOG", source="DOI:10.1016/j.ydbio.2005.02.021 Mazet F, Hutt JA, Milloz J, Millard J, Graham A, Shimeld SM, Molecular evidence from Ciona intestinalis for the evolutionary origin of vertebrate sensory placodes. Developmental Biology (2005)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "ganglionic" xsd:string property_value: x_1.1:contributor https://github.com/cmungall [Term] id: UBERON:0000046 name: stemma name: stemma {def="Eye-spots which may be set into a pit to reduce the angles of light that enters and affects the eyespot, to allow the organism to deduce the angle of incoming light. \n[http://en.wikipedia.org/wiki/Stemma http://en.wikipedia.org/wiki/Eye#Pit_eyes]"} namespace: uberon def: "Eye-spots which may be set into a pit to reduce the angles of light that enters and affects the eyespot, to allow the organism to deduce the angle of incoming light." [Wikipedia:Eye#Pit_eyes, Wikipedia:Stemma] subset: uberon_slim synonym: "pit eye" EXACT [Wikipedia:Eye#Pit_eyes] xref: Wikipedia:Stemma is_a: UBERON:0000047 ! simple eye property_value: AISM:0000171 "Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Stemmata are specific lateral eyes (the term “lateral ocelli” is inappropriate) of larvae of most groups of Holometabola. They are replaced by the adult compound eyes during the metamorphosis. The number ranges between seven and one and they are absent in different groups. Structurally, they resemble ommatidia and are suitable to perceive movements, directions and distances.\"" xsd:string property_value: RO:0002161 NCBITaxon:7742 [Term] id: UBERON:0000047 name: simple eye namespace: uberon def: "An eye with one concave chamber. Note that 'simple' does not imply a reduced level of complexity or acuity." [Wikipedia:Eye#Simple_eyes] subset: grouping_class subset: uberon_slim xref: TGMA:0000729 xref: Wikipedia:Eye#Simple_eyes is_a: UBERON:0000970 ! eye [Term] id: UBERON:0000055 name: vessel namespace: uberon def: "A tubular structure that contains, conveys body fluid, such as blood or lymph." [https://orcid.org/0000-0002-6601-2165] subset: grouping_class subset: human_reference_atlas subset: pheno_slim is_a: UBERON:0004111 ! anatomical conduit relationship: channel_for UBERON:0006314 ! bodily fluid property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0000056 name: ureter namespace: uberon def: "Muscular duct that propels urine from the kidneys to the urinary bladder, or related organs." [GO:0090189, Wikipedia:Ureter] subset: efo_slim subset: human_reference_atlas subset: major_organ subset: organ_slim subset: pheno_slim subset: uberon_slim synonym: "metanephric duct" RELATED [ISBN:0073040584, VHOG:0000605] xref: AAO:0010254 xref: BTO:0001409 xref: CALOHA:TS-1084 xref: EFO:0000930 xref: EHDAA2:0002139 xref: EHDAA:9341 xref: EMAPA:17950 xref: EV:0100097 xref: FMA:9704 xref: GAID:438 xref: galen:Ureter xref: MA:0000378 xref: MAT:0000120 xref: MESH:D014513 xref: MIAA:0000120 xref: NCIT:C12416 xref: SCTID:302511008 xref: UMLS:C0041951 {source="ncithesaurus:Ureter"} xref: VHOG:0000605 xref: Wikipedia:Ureter xref: XAO:0000144 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005179 ! pelvic region element is_a: UBERON:0006555 ! excretory tube is_a: UBERON:0015212 ! lateral structure relationship: channel_for UBERON:0001088 ! urine relationship: channels_from UBERON:0001224 ! renal pelvis relationship: channels_into UBERON:0001255 ! urinary bladder relationship: develops_from UBERON:0005081 {source="GO"} ! ureter ureteric bud relationship: in_lateral_side_of UBERON:0000468 ! multicellular organism relationship: part_of UBERON:0036295 ! renal pelvis/ureter property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/3/30/Urinary_system.svg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Anatomical structure consisting of long narrow duct which carries urine from the kidney to the urinary bladder.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010254", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "The duct of amniotes that carries urine from a metanephric kidney to the urinary bladder. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Glossary_G-29, Grande_L, Liem_KF, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000605", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "The first embryonic hint of a metanephros is the formation of the metanephric duct that appears as a ureteric diverticulum arising at the base of preexisting mesonephric duct. The ureteric diverticulum grows dorsally into the posterior region of the nephric ridge. Here it enlarges and stimulates the growth of metanephric tubules that come to make up the metanephric kidney. The metanephros becomes the adult kidney of amniotes, and the metanephric duct is usually called the ureter.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000605", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.543", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "ureteral" xsd:string property_value: UBPROP:0000007 "ureteric" xsd:string property_value: UBPROP:0000010 "in humans, consists of adventitial, muscular and mucoa layers" xsd:string [Term] id: UBERON:0000057 name: urethra namespace: uberon def: "The fibromuscular tubular canal through which urine is discharged from the bladder to the exterior via the external urinary meatus; in males, the urethra is joined by the ejaculatory ducts and serves as a passageway for semen during ejaculation, as well as a canal for urine during voiding; in females, the urethra is shorter and emerges above the vaginal opening." [MGI:anna, MP:0000537] subset: efo_slim subset: major_organ subset: organ_slim subset: pheno_slim subset: uberon_slim xref: BTO:0001426 xref: CALOHA:TS-1132 xref: EFO:0000931 xref: EMAPA:30901 xref: EV:0100099 xref: FMA:19667 xref: GAID:390 xref: galen:Urethra xref: MA:0000379 xref: MAT:0000121 xref: MESH:D014521 xref: MIAA:0000121 xref: NCIT:C12417 xref: SCTID:302513006 xref: UMLS:C0041967 {source="ncithesaurus:Urethra"} xref: VHOG:0001264 xref: Wikipedia:Urethra xref: XAO:0000153 is_a: UBERON:0000062 ! organ is_a: UBERON:0004111 ! anatomical conduit is_a: UBERON:0004120 ! mesoderm-derived structure relationship: capable_of_part_of GO:0060073 ! micturition relationship: channel_for UBERON:0001088 ! urine relationship: channels_from UBERON:0001255 ! urinary bladder relationship: continuous_with UBERON:0001255 ! urinary bladder relationship: develops_from UBERON:0000164 {notes="pelvic part of UG sinus gives rise to prostatic and membranous parts of urethra", source="Wikipedia"} ! primitive urogenital sinus relationship: develops_from UBERON:0013241 {source="Wikipedia"} ! embryonic urethral groove relationship: part_of UBERON:0001556 ! lower urinary tract property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/c/cb/Female_anatomy.png" xsd:anyURI property_value: UBPROP:0000007 "urethral" xsd:string property_value: UBPROP:0000008 "In human males, the urethra travels through the penis, and carries semen as well as urine. In females, the urethra is shorter and emerges above the vaginal opening." xsd:string [Term] id: UBERON:0000058 name: duct namespace: uberon def: "A tubular structure that transports secreted or excreted substances." [http://orcid.org/0000-0002-6601-2165, http://www.siumed.edu/~dking2/intro/glands.htm#ducts] subset: grouping_class synonym: "anatomical duct" EXACT [] synonym: "ducts" RELATED OMO:0003004 [XAO:0004000] synonym: "exocrine duct" NARROW [] synonym: "exocrine gland duct" NARROW [] xref: AAO:0011123 xref: FBbt:00100314 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:30320 xref: galen:Duct xref: NCIT:C12948 xref: SCTID:91726008 xref: TAO:0005171 xref: UMLS:C0687028 {source="ncithesaurus:Duct"} xref: Wikipedia:Duct_(anatomy) xref: XAO:0004000 xref: ZFA:0005171 is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000063 ! organ subunit relationship: conduit_for UBERON:0000463 ! organism substance relationship: has_part UBERON:0034969 ! epithelial layer of duct relationship: has_quality PATO:0002299 ! tubular property_value: UBPROP:0000001 "A tube shaped portion of tissue lined with epithelial cells that collects secretions and routes them to their destination[ZFA:0005171]." xsd:string {source="ZFA:0005171"} property_value: UBPROP:0000012 "Most ducts, but not all, are exocrine gland ducts. Some ontologies classify structures such as the oviduct here." xsd:string [Term] id: UBERON:0000059 name: large intestine namespace: uberon def: "A subdivision of the digestive tract that connects the small intestine to the cloaca or anus. Lacks or has few villi[Kardong]." [ISBN:0073040584, Wikipedia:Large_intestine_(anatomy)] subset: efo_slim subset: human_reference_atlas subset: major_organ subset: organ_slim subset: pheno_slim synonym: "intestinum crassum" RELATED [BTO:0000706] xref: AAO:0010396 xref: BTO:0000706 xref: CALOHA:TS-1306 xref: EFO:0000840 xref: EMAPA:19252 xref: EV:0100077 xref: FMA:7201 xref: GAID:306 xref: galen:LargeIntestine xref: MA:0000333 xref: MESH:D007420 xref: MIAA:0000046 xref: NCIT:C12379 xref: SCTID:181254001 xref: UMLS:C0021851 {source="ncithesaurus:Large_Intestine"} xref: VHOG:0000054 xref: Wikipedia:Large_intestine_(anatomy) xref: XAO:0000131 is_a: UBERON:0004921 {source="cjm"} ! subdivision of digestive tract is_a: UBERON:0013765 ! digestive system element relationship: contributes_to_morphology_of UBERON:0000160 ! intestine relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0000160 ! intestine relationship: part_of UBERON:0004907 ! lower digestive tract property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.0/SBU_F_Intestine_Large.glb" xsd:anyURI property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/SBU_F_Intestine_Large.glb" xsd:anyURI property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/SBU_M_Intestine_Large.glb" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000003 "Intestinal surface area also is increased in amphibians and reptiles by internal folds and occasionally by a few villi. The intestine can be divided into a small intestine and a slightly wider large intestine.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000054", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.566", source="http://bgee.unil.ch/"} [Term] id: UBERON:0000060 name: anatomical wall namespace: uberon alt_id: UBERON:0009915 def: "Organ component adjacent to an organ cavity and which consists of a maximal aggregate of organ component layers." [FMA:82482] subset: upper_level synonym: "organ wall" RELATED [FMA:82482] synonym: "wall" BROAD [] synonym: "wall of organ" EXACT [FMA:82482] xref: EMAPA:25036 xref: FMA:82482 xref: galen:Wall is_a: UBERON:0000064 ! organ part relationship: adjacent_to UBERON:0002553 ! anatomical cavity relationship: has_part UBERON:0004923 ! organ component layer property_value: UBPROP:0000012 "in FMA, serosa is a wall" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0000061 name: anatomical structure namespace: uberon def: "Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome." [CARO:0000003] subset: common_anatomy subset: human_subset subset: mouse_subset subset: upper_level synonym: "biological structure" EXACT [] synonym: "connected biological structure" EXACT [CARO:0000003] xref: AAO:0010825 xref: AEO:0000003 xref: BILA:0000003 xref: CARO:0000003 xref: EHDAA2:0003003 xref: EMAPA:0 xref: FBbt:00007001 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:305751 xref: FMA:67135 xref: GAID:781 xref: HAO:0000003 xref: http://dbpedia.org/ontology/AnatomicalStructure xref: MA:0003000 xref: MESH:D000825 xref: SCTID:362889002 xref: TAO:0000037 xref: TGMA:0001823 xref: VHOG:0001759 xref: XAO:0003000 xref: ZFA:0000037 is_a: UBERON:0000465 ! material anatomical entity relationship: existence_ends_during_or_before UBERON:0000071 ! death stage relationship: existence_starts_during_or_after UBERON:0000106 {gci_relation="in_taxon", gci_filler="NCBITaxon:33208"} ! zygote stage property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0000062 name: organ namespace: uberon def: "Anatomical structure that performs a specific function or group of functions [WP]." [Wikipedia:Organ_(anatomy)] subset: common_anatomy subset: upper_level synonym: "anatomical unit" RELATED [] synonym: "body organ" RELATED [] synonym: "element" RELATED [http://orcid.org/0000-0002-6601-2165] xref: BIRNLEX:4 xref: CARO:0020004 xref: EFO:0000634 xref: EMAPA:35949 xref: ENVO:01000162 xref: FMA:67498 xref: MA:0003001 xref: NCIT:C13018 xref: SCTID:272625005 xref: UMLS:C0178784 {source="ncithesaurus:Organ"} xref: WBbt:0003760 xref: Wikipedia:Organ_(anatomy) is_a: UBERON:0010000 ! multicellular anatomical structure disjoint_from: UBERON:0002095 {source="PMID:28192867"} ! mesentery disjoint_from: UBERON:0034921 ! multi organ part structure relationship: capable_of GO:0008150 ! biological process relationship: existence_starts_during_or_after UBERON:0000111 {gci_filler="NCBITaxon:6072", gci_relation="in_taxon"} ! organogenesis stage relationship: has_boundary UBERON:0006984 ! anatomical surface relationship: part_of UBERON:0000467 ! anatomical system property_value: RO:0002161 NCBITaxon:110815 {source="Wikipedia"} property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 property_value: UBPROP:0000001 "Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." xsd:string {source="GO:0048513"} property_value: UBPROP:0000012 "CARO v1 does not include a generic 'organ' class, only simple and compound organ. CARO v2 may include organ, see https://github.com/obophenotype/caro/issues/4" xsd:string [Term] id: UBERON:0000063 name: organ subunit namespace: uberon def: "A part of an organ that constitutes a distinct modular sub-unit. In some cases, the organ may also contain other sub-units of identical or similar types, in other cases this may be a distinct entity." [http://orcid.org/0000-0002-6601-2165] subset: upper_level synonym: "organ region with fixed fiat boundary" RELATED [FMA:86140] synonym: "organ segment" RELATED [FMA:86140] synonym: "segment of organ" RELATED [FMA:86140] xref: FMA:86140 is_a: UBERON:0000064 ! organ part property_value: editor_note "FMA distinguishes segment from zone by whether the fiat boundaries are fixed/anchored (segments) or floating (zone). It's not completely clear how to apply this distinction" xsd:string property_value: UBPROP:0000001 "Organ region with one or more anchored fiat boundaries. Examples: artery, trunk of nerve, cervical part of esophagus, pelvic part of vagina, horn of thyroid cartilage, anterior segment of eyeball." xsd:string {source="FMA:86140", version="3"} property_value: UBPROP:0000001 "Organ region with one or more fixed or anchored fiat boundaries. Examples: artery, trunk of nerve, cervical part of esophagus, pelvic part of vagina, horn of thyroid cartilage, anterior segment of eyebal." xsd:string {source="FMA:86140", version="1"} [Term] id: UBERON:0000064 name: organ part namespace: uberon def: "A multicellular structure that is a part of an organ." [http://orcid.org/0000-0002-6601-2165] subset: common_anatomy subset: efo_slim subset: non_informative subset: upper_level synonym: "cardinal organ part" EXACT [FMA:82472] synonym: "regional part of organ" RELATED [BIRNLEX:16] xref: AAO:0011124 xref: BIRNLEX:16 xref: EFO:0000635 xref: FMA:82472 xref: SCTID:113343008 xref: SCTID:91717005 is_a: UBERON:0010000 ! multicellular anatomical structure relationship: part_of UBERON:0000062 ! organ property_value: curator_notes "currently defined in a very broad sense, may be replaced by more specific classes in the future" xsd:string property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0000065 name: respiratory tract namespace: uberon def: "Anatomical structure that is part of the respiratory system. In mammals consists of upper and lower tracts." [https://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas xref: EHDAA2:0001606 xref: EHDAA:1568 xref: EHDAA:2219 xref: EMAPA:16737 xref: FMA:265130 xref: SCTID:361110005 xref: VHOG:0000393 is_a: UBERON:0001005 ! respiratory airway is_a: UBERON:0004119 ! endoderm-derived structure relationship: develops_from UBERON:0007026 {source="NCBIBook:NBK10107"} ! presumptive gut relationship: develops_from UBERON:0008947 ! respiratory primordium property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0000066 name: fully formed stage namespace: uberon def: "The stage of development at which the animal is fully formed, including immaturity and maturity. Includes both sexually immature stage, and adult stage." [https://orcid.org/0000-0002-6601-2165] subset: efo_slim synonym: "adult stage" BROAD [] synonym: "fully formed animal stage" EXACT [] synonym: "juvenile-adult stage" EXACT [] xref: BilaDO:0000004 xref: BTO:0001043 xref: EFO:0001272 xref: FBdv:00005369 xref: WBls:0000041 xref: XtroDO:0000084 is_a: UBERON:0000105 ! life cycle stage relationship: part_of UBERON:0000092 ! post-embryonic stage relationship: preceded_by UBERON:0000111 ! organogenesis stage relationship: preceded_by UBERON:0004729 {gci_relation="part_of", gci_filler="NCBITaxon:6239"} ! nematode larval stage relationship: precedes UBERON:0000071 ! death stage property_value: seeAlso "https://github.com/obophenotype/uberon/issues/566" xsd:anyURI [Term] id: UBERON:0000068 name: embryo stage namespace: uberon def: "A life cycle stage that starts with fertilization and ends with the fully formed embryo." [http://orcid.org/0000-0002-6601-2165] synonym: "embryogenesis" RELATED [] synonym: "embryonic stage" EXACT [] xref: BilaDO:0000002 xref: EV:0300001 xref: FBdv:00005289 xref: FMA:72652 xref: HsapDv:0000002 xref: MmusDv:0000002 xref: OGES:000000 xref: OGES:000022 xref: SCTID:296280003 xref: WBls:0000003 xref: WBls:0000092 xref: WBls:0000102 xref: XAO:1000012 is_a: UBERON:0000105 ! life cycle stage disjoint_from: UBERON:0000092 ! post-embryonic stage relationship: precedes UBERON:0000066 ! fully formed stage relationship: precedes UBERON:0000092 ! post-embryonic stage relationship: simultaneous_with GO:0009790 ! embryo development [Term] id: UBERON:0000069 name: larval stage namespace: uberon def: "A distinct juvenile stage many animals undergo before metamorphosis into adults. Animals with indirect development such as insects, amphibians, or cnidarians typically have a larval phase of their life cycle." [Wikipedia:Larva] subset: efo_slim synonym: "ammocoete" NARROW SENSU [Wikipedia:Larva] synonym: "ammocoete stage" NARROW SENSU [Wikipedia:Larva] synonym: "bipinnaria" NARROW SENSU [Wikipedia:Larva] synonym: "bipinnaria stage" NARROW SENSU [Wikipedia:Larva] synonym: "caterpillar" NARROW SENSU [Wikipedia:Larva] synonym: "caterpillar stage" NARROW SENSU [Wikipedia:Larva] synonym: "glochidium" NARROW SENSU [Wikipedia:Larva] synonym: "glochidium stage" NARROW SENSU [Wikipedia:Larva] synonym: "grub" NARROW SENSU [Wikipedia:Larva] synonym: "grub stage" NARROW SENSU [Wikipedia:Larva] synonym: "larva" RELATED [] synonym: "larva stage" EXACT [] synonym: "leptocephalus" NARROW SENSU [Wikipedia:Larva] synonym: "leptocephalus stage" NARROW SENSU [Wikipedia:Larva] synonym: "maggot" NARROW SENSU [Wikipedia:Larva] synonym: "maggot stage" NARROW SENSU [Wikipedia:Larva] synonym: "metacestode" NARROW SENSU [BTO:0000859] synonym: "naiad, nymph" NARROW SENSU [Wikipedia:Larva] synonym: "naiad, nymph stage" NARROW SENSU [Wikipedia:Larva] synonym: "nauplius" NARROW SENSU [Wikipedia:Larva] synonym: "nauplius stage" NARROW SENSU [Wikipedia:Larva] synonym: "nymph" NARROW SENSU [Wikipedia:Larva] synonym: "nymph stage" NARROW SENSU [Wikipedia:Larva] synonym: "planula" NARROW SENSU [Wikipedia:Larva] synonym: "planula stage" NARROW SENSU [Wikipedia:Larva] synonym: "tornaria" NARROW SENSU [NCBITaxon:10219] synonym: "trochophore" NARROW SENSU [Wikipedia:Larva] synonym: "trochophore stage" NARROW SENSU [Wikipedia:Larva] synonym: "veliger" NARROW SENSU [Wikipedia:Larva] synonym: "veliger stage" NARROW SENSU [Wikipedia:Larva] synonym: "wriggler" NARROW SENSU [Wikipedia:Larva] synonym: "wriggler stage" NARROW SENSU [Wikipedia:Larva] synonym: "zoea" NARROW SENSU [Wikipedia:Larva] synonym: "zoea stage" NARROW SENSU [Wikipedia:Larva] xref: BTO:0000915 xref: BTO:0000954 xref: EFO:0001303 xref: FBdv:00005336 xref: MIAA:0000400 xref: OGES:000008 xref: Wikipedia:Larva xref: ZFS:0000048 is_a: UBERON:0000105 ! life cycle stage relationship: immediately_preceded_by UBERON:0000068 ! embryo stage relationship: part_of UBERON:0000092 ! post-embryonic stage relationship: simultaneous_with GO:0002164 ! larval development property_value: curator_notes "Uberon includes clade-specific subclasses, e.g. nematod larva" xsd:string property_value: RO:0002161 NCBITaxon:32524 property_value: UBPROP:0000008 "It is a misunderstanding that the larval form always reflects the group's evolutionary history. It could be the case, but often the larval stage has evolved secondarily, as in insects. In these cases the larval form might differ more from the group's common origin than the adult form" xsd:string {source="WP"} [Term] id: UBERON:0000071 name: death stage namespace: uberon def: "End of the life of an organism." [XAO:0000437] subset: common_anatomy synonym: "death" RELATED [] xref: XAO:0000437 xref: XtroDO:0000085 is_a: UBERON:0000105 ! life cycle stage relationship: ends UBERON:0000104 ! life cycle property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 property_value: UBPROP:0000012 "ncit:Death is an outcome" xsd:string {external_ontology="ncit"} [Term] id: UBERON:0000072 name: proximo-distal subdivision of respiratory tract namespace: uberon def: "An section of a respiratory tract." [http://orcid.org/0000-0002-6601-2165] subset: non_informative synonym: "respiratory tract" RELATED [MA:0000434] synonym: "subdivision of respiratory tract" RELATED [] xref: EMAPA:16737 xref: FMA:45660 xref: MA:0000434 is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0013522 ! subdivision of tube intersection_of: UBERON:0013522 ! subdivision of tube intersection_of: part_of UBERON:0000065 ! respiratory tract relationship: part_of UBERON:0000065 ! respiratory tract property_value: UBPROP:0000012 "MA:0000434 has subclasses upper and lower, so it corresponds to a segment of the tract, rather than the tract as a whole" xsd:string {external_ontology="MA"} [Term] id: UBERON:0000073 name: regional part of nervous system namespace: uberon def: "Any part or collection of parts of the central or peripheral nervous system. Parts may span both CNS and PNS." [BIRNLEX:1157] subset: non_informative subset: upper_level synonym: "part of nervous system" EXACT [BIRNLEX:1157] xref: BIRNLEX:1157 xref: NCIT:C13040 xref: SCTID:25087005 xref: UMLS:C1518256 {source="ncithesaurus:Nervous_System_Part"} is_a: UBERON:0000481 ! multi-tissue structure intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: part_of UBERON:0001016 ! nervous system relationship: part_of NCBITaxon:6072 ! Eumetazoa relationship: part_of UBERON:0001016 ! nervous system property_value: term:contributor https://orcid.org/0000-0001-9114-8737 creation_date: 2009-06-18T09:00:04Z [Term] id: UBERON:0000075 name: subdivision of skeletal system namespace: uberon alt_id: UBERON:0010322 def: "Anatomical cluster consisting of the skeletal elements and articular elements that are part of an individual subdivision of the organism." [https://orcid.org/0000-0002-6601-2165, UBERONREF:0000003] subset: non_informative synonym: "skeletal system part" RELATED [] synonym: "skeletal system subdivision" EXACT [FMA:85544] xref: FMA:85544 xref: galen:ComplexSkeletalStructure xref: NCIT:C34076 xref: SCTID:118966000 xref: UMLS:C1519343 {source="ncithesaurus:Skeletal_System_Part"} is_a: UBERON:0011216 {source="cjm"} ! organ system subdivision relationship: composed_primarily_of UBERON:0004765 ! skeletal element relationship: only_in_taxon NCBITaxon:7711 ! Chordata relationship: part_of UBERON:0001434 ! skeletal system [Term] id: UBERON:0000076 name: external ectoderm namespace: uberon def: "The surface (external) layer of ectoderm which begins to proliferate shortly after separation from the neuroectoderm." [MGI:anna, MP:0012532] subset: pheno_slim synonym: "surface (external) ectoderm" EXACT [] synonym: "surface ectoderm" EXACT [MP:0012532] xref: BTO:0006242 {sssom:mapping_justification="vocab:ManualMappingCuration", sssom:author_id="https://orcid.org/0000-0003-4423-4370", sssom:mapping_provider="https://github.com/biopragmatics/biomappings"} xref: EHDAA2:0001968 xref: EHDAA:1494 xref: EHDAA:350 xref: EHDAA:4784 xref: EHDAA:4790 xref: EHDAA:4796 xref: EHDAA:7860 xref: EMAPA:16096 xref: FMA:87656 xref: NCIT:C34309 xref: UMLS:C1515087 {source="ncithesaurus:Surface_Ectoderm"} xref: Wikipedia:External_ectoderm is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium is_a: UBERON:0005291 ! embryonic tissue relationship: part_of UBERON:0000924 {source="EHDAA2"} ! ectoderm property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/1/1d/Ectoderm.png" xsd:anyURI property_value: editor_note "merge with non-neural. In vertebrates, the ectoderm has three parts: external ectoderm (also known as surface ectoderm), the neurectoderm (neural crest, and neural tube)" xsd:string property_value: RO:0002171 UBERON:0002346 property_value: UBPROP:0000011 "(or external ectoderm) forms the following structures: Skin Epithelium of the mouth and nasal cavity saliavary glands, and glands of mouth and nasal cavity Enamel - as a side note dentin and dental pulp are formed from ectomesenchyme which is derived from ectoderm Epithelium of pineal and pituitary glands Lens and cornea of the eye Apical ectodermal ridge inducing development of the limb buds of the embryo. Sensory receptors in epidermis" xsd:string [Term] id: UBERON:0000077 name: mixed endoderm/mesoderm-derived structure namespace: uberon def: "An anatomical structure that develops from the endoderm and the mesoderm." [https://orcid.org/0000-0002-6601-2165] subset: grouping_class is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0000061 ! anatomical structure intersection_of: develops_from UBERON:0000925 ! endoderm intersection_of: develops_from UBERON:0000926 ! mesoderm property_value: curator_notes "Grouping term for query purposes. Notes that the developmental relationships are being refined such that most structures should develop in whole from at most one layer, but may have contributions from multiple" xsd:string [Term] id: UBERON:0000078 name: mixed ectoderm/mesoderm/endoderm-derived structure namespace: uberon def: "An anatomical structure that develops from the ectoderm, mesoderm and endoderm." [https://orcid.org/0000-0002-6601-2165] subset: grouping_class is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0000061 ! anatomical structure intersection_of: develops_from UBERON:0000924 ! ectoderm intersection_of: develops_from UBERON:0000925 ! endoderm intersection_of: develops_from UBERON:0000926 ! mesoderm property_value: curator_notes "Grouping term for query purposes. Notes that the developmental relationships are being refined such that most structures should develop in whole from at most one layer, but may have contributions from multiple" xsd:string [Term] id: UBERON:0000079 name: male reproductive system namespace: uberon def: "The organs associated with producing offspring in the gender that produces spermatozoa." [MP:0001145] subset: efo_slim subset: human_reference_atlas subset: pheno_slim synonym: "genitalia of male organism" EXACT [OBOL:automatic] synonym: "male genital organ" RELATED [BTO:0000082] synonym: "male genital system" EXACT [FMA:45664] synonym: "male genital tract" RELATED [] synonym: "male genitalia" EXACT [] synonym: "male genitals" EXACT [] synonym: "male organism genitalia" EXACT [OBOL:automatic] synonym: "male organism reproductive system" EXACT [OBOL:automatic] synonym: "male reproductive tract" RELATED [MA:0000396] synonym: "reproductive system of male organism" EXACT [OBOL:automatic] synonym: "systema genitale masculinum" RELATED [BTO:0000082] xref: BTO:0000082 xref: CALOHA:TS-1310 xref: EFO:0000970 xref: EHDAA2:0001054 xref: EHDAA:8136 xref: EMAPA:17968 xref: EV:0100101 xref: FBbt:00004927 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:45664 xref: GAID:386 xref: HAO:0000505 xref: MA:0000396 xref: MESH:D005837 xref: NCIT:C12722 xref: SCTID:361340001 xref: TGMA:0000634 xref: UMLS:C0017422 {source="ncithesaurus:Male_Genitalia"} xref: UMLS:C1963704 {source="ncithesaurus:Male_Reproductive_System"} xref: VHOG:0000725 xref: Wikipedia:Male_reproductive_system_(human) xref: XAO:0000155 is_a: UBERON:0000990 ! reproductive system intersection_of: UBERON:0000990 ! reproductive system intersection_of: part_of UBERON:0003101 ! male organism disjoint_from: UBERON:0000474 ! female reproductive system relationship: part_of UBERON:0003101 ! male organism property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Prostate.glb" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000003 "By far, sexual reproduction is the more common pattern among living vertebrate forms and its widespread occurrence suggests that it is the plesiomorphic, or primitive, reproductive mode among the vertebrates.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000725", ontology="VHOG", source="ISBN:978-0792383369 Lombardi J, Comparative vertebrate reproduction (1998) p.43", source="http://bgee.unil.ch/"} [Term] id: UBERON:0000080 name: mesonephros namespace: uberon def: "The second stage of the kidney. It serves as the main excretory organ of aquatic vertebrates and as a temporary embryonic kidney in higher vertebrates. It is composed of the mesonephric duct (also called the Wolffian duct), mesonephric tubules, and associated capillary tufts. A single tubule and its associated capillary tuft is called a mesonephric excretory unit; these units are similar in structure and function to nephrons of the adult kidney. The mesonephros is derived from intermediate mesoderm in the vertebrate embryo." [GO:0001823, Wikipedia:Mesonephros] subset: efo_slim subset: organ_slim subset: pheno_slim subset: vertebrate_core synonym: "amphibian adult kidney" RELATED [XAO:0000141] synonym: "corpus Wolffi" RELATED [BTO:0001542] synonym: "mesonephric kidney" EXACT [XAO:0000141] synonym: "mesonephroi" EXACT OMO:0003004 [http://www.gudmap.org/About/Tutorial/DevMUS.html#DMK_Nephron] synonym: "middle kidney" RELATED [BTO:0001542] synonym: "opisthonephros" RELATED [VHOG:0000038, XAO:0000141] synonym: "opisto nephros" RELATED [] synonym: "opistonephros" RELATED [http://www.usm.maine.edu/bio/courses/bio205/bio205_26_sex.html] synonym: "Wolffian body" EXACT [BTO:0001542, GOC:yaf, MESH:A16.254.500, Wikipedia:Mesonephros] xref: AAO:0010384 xref: BTO:0001542 xref: CALOHA:TS-0624 xref: EFO:0000928 xref: EHDAA2:0001130 xref: EHDAA:1581 xref: EHDAA:5903 xref: EMAPA:16744 xref: FMA:72171 xref: GAID:1308 xref: MESH:D001755 xref: NCIT:C26467 xref: SCTID:308799002 xref: TAO:0000529 xref: UMLS:C0025492 {source="ncithesaurus:Mesonephros"} xref: VHOG:0000038 xref: Wikipedia:Mesonephros xref: XAO:0000141 xref: ZFA:0000529 is_a: UBERON:0002113 ! kidney is_a: UBERON:0004120 ! mesoderm-derived structure relationship: develops_from UBERON:0002120 ! pronephros property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/a/ad/Gray986.png" xsd:anyURI property_value: UBPROP:0000001 "A kidney formed of nephric tubules arising in the middle region of the nephric ridge; a transient embryonic stage that replaces the pronephros, but is itself replaced by the adult metanephros [in mammals; in fishes and amphibians it is the adult kidney]. [Evolution, Fourth_Edition_(2006)_McGraw-Hill, Function, Kardong_KV, Vertebrates:_Comparative_Anatomy, p.745][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000038", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000001 "Organ that is the definitive adult kidney. It replaces the earlier pronephros, which degenerates as the mesonephros becomes functional in feeding stage tadpoles.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010384", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000003 "As the pronephros regresses, the archinephric duct induces the sequential differentiation of tubules in the more caudal parts of the nephric ridge. (...) Tubules that differentiate in the middle part of the nephric ridge form a kidney called the mesonephros. This kidney functions in the embryos and larvae of all vertebrates. (...) In all vertebrate embryos, the kidney begins with the differentiation of a few renal tubules from the anterior end of the nephric ridge overlying the pericardial cavity. (...) This early-developing embryonic kidney is called the pronephros.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000038", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.639", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "mesonephric" xsd:string property_value: UBPROP:0000008 "In mammals, the mesonephros is the second of the three embryonic kidneys to be established and exists only transiently. In fish and amphibians, the mesonephros will form the mature kidney" xsd:string property_value: UBPROP:0000009 "By contrast to the pronephros, the histological features of the mammalian mesonephros, with its primitive glomeruli, suggest that it probably functions as a primitive kidney, and is involved in the production of much of the amniotic fluid. Within the two mesonephroi, one located on either side of the dorsal mesentery of the hindgut, a substantial number (in the region of about 40 or more) of cranio-caudally segmented mesonephric tubules are formed. It has, however, been suggested that only the most rostrally located 4-6 pairs of mesonephric tubules drain into the mesonephric portion of the nephric duct. This is now seen to extend along the length of the mesonephroi, being located towards their lateral sides. The mesonephros is also retained over a considerably longer period than the pronephros, but gradually undergoes regression in a cranio-caudal direction. While the rostral part displays clear evidence of regression its more caudal part appears to display evidence of functional activity. Within the medial part of the mesonephros, vesicles are formed, although no glomeruli are formed there in this species. It is, however, difficult to believe that the relatively enormous mesonephroi do not have an excretory role in the mouse, only serving as a base for gonadal differentiation. In the human embryo, the medial part of the mesonephric tubules enlarges, become invaginated by capillaries, and form glomeruli. These then take on an excretory role. In the mouse, the mesonephric ducts appear to be patent throughout their length[GUDMAP, modified]" xsd:string [Term] id: UBERON:0000081 name: metanephros namespace: uberon def: "In mammals, the metanephros is the excretory organ of the fetus, which develops into the mature kidney and is formed from the rear portion of the nephrogenic cord. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine[GO]." [GO:0001656, Wikipedia:Metanephros#Metanephros] subset: organ_slim subset: pheno_slim synonym: "definite kidney" RELATED [BTO:0001543] synonym: "definitive kidney" RELATED [BTO:0001543] synonym: "hind kidney" RELATED [BTO:0001543] synonym: "metanephric kidney" RELATED [VHOG:0000039] synonym: "metanephron" EXACT [BTO:0001543] xref: BTO:0001543 xref: EHDAA2:0001137 xref: EHDAA:3089 xref: EHDAA:5911 xref: EMAPA:17373 xref: EMAPA_RETIRED:17207 xref: FMA:72172 xref: NCIT:C34209 xref: SCTID:308797000 xref: UMLS:C0231049 {source="ncithesaurus:Metanephros"} xref: VHOG:0000039 xref: Wikipedia:Metanephros#Metanephros is_a: UBERON:0002113 ! kidney is_a: UBERON:0004120 ! mesoderm-derived structure relationship: developmentally_replaces UBERON:0000080 {source="ISBN:9780878932504"} ! mesonephros relationship: develops_from UBERON:0003220 {evidence="definitional"} ! metanephric mesenchyme relationship: develops_from UBERON:0005080 {source="GO"} ! metanephric ureteric bud relationship: develops_from UBERON:0005753 ! caudal part of nephrogenic cord relationship: existence_ends_during UBERON:0000066 ! fully formed stage property_value: editor_note "TODO check developmental relationships" xsd:string property_value: UBPROP:0000001 "A kidney formed of nephric tubules arising in the posterior region of the nephric ridge and drained by a ureter; replaces the embryonic pronephros and mesonephros [in mammals]. [Evolution, Fourth_Edition_(2006)_McGraw-Hill, Function, Kardong_KV, Vertebrates:_Comparative_Anatomy, p.745][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000039", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "The ureteric diverticulum grows dorsally into the posterior region of the nephric ridge. Here it enlarges and stimulates the growth of metanephric tubules that come to make up the metanephric kidney. The metanephros becomes the adult kidney of amniotes.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000039", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.543", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "metanephric" xsd:string property_value: UBPROP:0000011 "During the fifth week of gestation, the mesonephric duct develops an outpouching, the ureteric bud, near its attachment to the cloaca. This bud, also called the metanephrogenic diverticulum, grows posteriorly and towards the head of the embryo. The elongated stalk of the ureteric bud, the metanephric duct, later forms the ureter. As the cranial end of the bud extends into the intermediate mesoderm, it undergoes a series of branchings to form the collecting duct system of the kidney. It also forms the major and minor calyces and the renal pelvis" xsd:string [Term] id: UBERON:0000083 name: mesonephric tubule namespace: uberon def: "A mesonephric tubule is an epithelial tube that is part of the mesonephros[GO]. Genital ridge that is next to the mesonephros[WP]." [Wikipedia:Mesonephric_tubules] synonym: "renal tubules" RELATED OMO:0003004 [VHOG:0000500] synonym: "tubuli mesonephrici" RELATED OMO:0003011 [Wikipedia:Mesonephric_tubules] xref: AAO:0010389 xref: EHDAA2:0001134 xref: EMAPA:16747 xref: VHOG:0000500 xref: Wikipedia:Mesonephric_tubules xref: XAO:0000148 is_a: UBERON:0003914 ! epithelial tube is_a: UBERON:0005103 ! mesonephric epithelium is_a: UBERON:0006555 ! excretory tube intersection_of: UBERON:0003914 ! epithelial tube intersection_of: part_of UBERON:0000080 ! mesonephros property_value: editor_note "TODO check" xsd:string property_value: UBPROP:0000001 "Any of the renal tubules composing the mesonephros. In mammals they function as excretory structures during the early embryonic development but are later incorporated into the reproductive system. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000500", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/mesonephric+tubule"} property_value: UBPROP:0000003 "As the pronephros regresses, the archinephric duct induces the sequential differentiation of tubules in the more caudal parts of the nephric ridge. (...) Tubules that differentiate in the middle part of the nephric ridge form a kidney called the mesonephros. This kidney functions in the embryos and larvae of all vertebrates.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000500", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.639", source="http://bgee.unil.ch/"} [Term] id: UBERON:0000084 name: ureteric bud namespace: uberon def: "An epithelial swelling on the Wolffian duct that elongates to invade the adjacent metanephric mesenchyme[MP]." [MP:0010979, PMID:19828308] subset: pheno_slim synonym: "diverticulum" RELATED [BTO:0001646] synonym: "diverticulum metanephricum" RELATED OMO:0003011 [Wikipedia:Ureteric_bud] synonym: "gemma ureterica" RELATED OMO:0003011 [Wikipedia:Ureteric_bud] synonym: "metanephric bud" RELATED [BTO:0001646] synonym: "metanephric diverticulum" RELATED [Wikipedia:Metanephros#Metanephros] synonym: "ureteric ampulla" RELATED [] synonym: "ureteric diverticulum" RELATED [VHOG:0000541] xref: BTO:0001646 xref: EHDAA2:0002140 xref: EHDAA:3091 xref: EHDAA:5917 xref: EMAPA:17209 xref: NCIT:C34207 xref: SCTID:361528000 xref: UMLS:C1284058 {source="ncithesaurus:Metanephric_Diverticulum"} xref: VHOG:0000541 xref: Wikipedia:Ureteric_bud is_a: UBERON:0000083 ! mesonephric tubule is_a: UBERON:0007499 {source="EHDAA2"} ! epithelial sac is_a: UBERON:0034969 ! epithelial layer of duct relationship: developmentally_induced_by UBERON:0003220 {source="ISBN:9780878932504"} ! metanephric mesenchyme relationship: develops_from UBERON:0003074 {source="EHDAA2"} ! mesonephric duct relationship: part_of UBERON:0003074 ! mesonephric duct property_value: UBPROP:0000001 "Outgrowth of the mesonephric duct that penetrates the metanephric mesoderm and forms the ureter, renal pelvis, major and minor calyces and collecting ducts. [Embryology, See_Dudek_RW_and_Fix_JD, Third_Edition_(2004)_Philadelphia:_Lippincott_William_and_Wilkins, p.137][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000541", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000001 "Outgrowth of the mesonephric duct that penetrates the metanephric mesoderm and forms the ureter, renal pelvis, major and minor calyces and collecting ducts[VHOG:0000541]." xsd:string {source="VHOG:0000541"} property_value: UBPROP:0000003 "The first embryonic hint of a metanephros is the formation of the metanephric duct that appears as a ureteric diverticulum arising at the base of preexisting mesonephric duct. The ureteric diverticulum grows dorsally into the posterior region of the nephric ridge. Here it enlarges and stimulates the growth of metanephric tubules that come to make up the metanephric kidney. The metanephros becomes the adult kidney of amniotes, and the metanephric duct is usually called the ureter.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000541", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.543", source="http://bgee.unil.ch/"} [Term] id: UBERON:0000085 name: morula namespace: uberon def: "A spherical embryonic mass of blastomeres formed before the blastula and resulting from cleavage of the fertilized ovum." [MP:0012130] subset: pheno_slim synonym: "morula (2-16 cells)" RELATED [EHDAA2:0000005] xref: BTO:0001508 xref: EHDAA2:0000005 xref: FMA:292334 xref: GAID:1295 xref: MESH:D009028 xref: NCIT:C34212 xref: SCTID:361474003 xref: UMLS:C0026573 {source="ncithesaurus:Morula"} xref: Wikipedia:Morula is_a: UBERON:0000922 ! embryo relationship: existence_ends_during UBERON:0000107 ! cleavage stage relationship: existence_starts_during UBERON:0000107 ! cleavage stage relationship: has_part CL:0000353 ! blastoderm cell relationship: part_of UBERON:0004716 {source="EHDAA2"} ! conceptus relationship: surrounded_by UBERON:0000086 ! zona pellucida property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/c/c6/Blastulation.png" xsd:anyURI property_value: UBPROP:0000012 "EHDAA2 has embryo starting later" xsd:string {external_ontology="EHDAA2"} [Term] id: UBERON:0000086 name: zona pellucida namespace: uberon def: "A glycoprotein membrane surrounding the plasma membrane of an oocyte. It is a vital constitutive part of the latter, external but not extraneous to it. The zona pellucida first appears in multilaminar primary oocytes." [Wikipedia:Zona_pellucida] subset: human_reference_atlas subset: pheno_slim subset: vertebrate_core synonym: "oolemma" RELATED [BTO:0003135] synonym: "pellucid zone" RELATED [BTO:0003135] synonym: "striated membrane" RELATED [BTO:0003135] synonym: "vitelline envelope" RELATED [] synonym: "vitelline membrane" RELATED [] synonym: "zona pellucida - vitelline membrane" BROAD [VHOG:0000720] synonym: "zona radiata" RELATED [BTO:0003135] synonym: "zona striata" RELATED [BTO:0003135] xref: BTO:0003135 xref: EHDAA2:0002220 xref: EHDAA:31 xref: EHDAA:62 xref: EMAPA:16035 xref: FMA:18674 xref: GAID:410 xref: MA:0001715 xref: MESH:D015044 xref: NCIT:C33896 xref: TAO:0001111 xref: UMLS:C0043519 {source="ncithesaurus:Zona_Pellucida"} xref: VHOG:0000720 xref: Wikipedia:Zona_pellucida xref: ZFA:0001111 is_a: UBERON:0005764 ! acellular membrane relationship: bounding_layer_of CL:0000023 ! oocyte relationship: has_part CHEBI:17089 ! glycoprotein relationship: part_of CL:0000023 ! oocyte relationship: part_of UBERON:0000992 ! ovary property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/8/81/Gray3.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000003 "Outside the plasma membrane, three envelopes surround the ovum. The first, the primary egg envelope, lies between the plasma membrane and the surrounding cells of the ovary. The most consistent component of this primary layer is the vitelline membrane, a transparent jacket of fibrous protein. In mammals, the homologous structure is called the zona pellucida.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000720", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.159", source="http://bgee.unil.ch/"} [Term] id: UBERON:0000087 name: inner cell mass namespace: uberon def: "A mass of cells that develop into the body of the embryo and some extraembryonic tissues." [ISBN:0-683-40008-8, MGI:pvb] subset: early_development subset: efo_slim subset: pheno_slim synonym: "early embryoblast" RELATED [FMA:86557] synonym: "embryoblast" RELATED [] synonym: "embryoblastus; massa cellularis interna; pluriblastus senior" RELATED OMO:0003011 [Wikipedia:Inner_cell_mass] synonym: "ICM" RELATED [VHOG:0000742] synonym: "pluriblast" RELATED [] xref: EFO:0000547 xref: EHDAA2:0000830 xref: EHDAA:40 xref: EMAPA:16041 xref: FMA:86557 xref: NCIT:C13740 xref: SCTID:361456007 xref: UMLS:C1283994 {source="ncithesaurus:Inner_Cell_Mass"} xref: VHOG:0000742 xref: Wikipedia:Inner_cell_mass is_a: UBERON:0002050 ! embryonic structure relationship: develops_from UBERON:0000358 {source="Wikipedia"} ! blastocyst relationship: surrounded_by UBERON:0000088 {source="Wikipedia"} ! trophoblast property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/7/72/Blastocyst_English.svg" xsd:anyURI property_value: UBPROP:0000001 "A group of cells found in the mammalian blastocyst that give rise to the embryo. [Biology_Online][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000742", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "A small sphere of cells known as the inner cell mass lies within the trophoblast (of all eutherian mammals).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000742", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.144", source="http://bgee.unil.ch/"} property_value: UBPROP:0000011 "This structure forms in the earliest steps of development, before implantation into the endometrium of the uterus has occurred.The ICM lies within the blastocyst cavity and is entirely surrounded by the single layer of cells called trophoblast. [Wikipedia:Inner_cell_mass]" xsd:string [Term] id: UBERON:0000088 name: trophoblast namespace: uberon def: "The mesectodermal cell layer arising from the trophectoderm that erodes the uterine mucosa and contributes to the formation of the placenta." [ISBN:0-683-40008-8, MP:0005031] comment: Aggregate of cells forming the outer layer of a blastocyst, which provide nutrients to the embryo and develop into a large part of the placenta. They are formed during the first stage of pregnancy and are the first cells to differentiate from the fertilized egg. [Wikipedia:Trophoblast] subset: early_development subset: pheno_slim synonym: "massa cellularis externa" RELATED OMO:0003011 [Wikipedia:Trophoblast] synonym: "trophoblast layer" EXACT [MP:0005031] synonym: "trophoblastus" RELATED OMO:0003011 [Wikipedia:Trophoblast] synonym: "trophoderm" RELATED [BTO:0001079] xref: BTO:0001079 xref: CALOHA:TS-1070 xref: EV:0100120 xref: FMA:83029 xref: GAID:1152 xref: MESH:D014327 xref: NCIT:C93292 xref: SCTID:362839005 xref: UMLS:C0041178 {source="ncithesaurus:Trophoblast"} xref: Wikipedia:Trophoblast is_a: UBERON:0002050 ! embryonic structure relationship: composed_primarily_of CL:0000351 ! trophoblast cell relationship: develops_from UBERON:0004345 {source="MP-def", source="PMID:19829370"} ! trophectoderm relationship: part_of UBERON:0000358 ! blastocyst property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/7/72/Blastocyst_English.svg" xsd:anyURI property_value: UBPROP:0000001 "the mesectodermal cell layer arising from the trophectoderm that erodes the uterine mucosa and contributes to the formation of the placenta[MP]" xsd:string {date_retrieved="2012-08-23", external_class="MP:0005031", external_class_label="trophoblast layer", ontology="MP", source="ISBN:0-683-40008-8"} property_value: UBPROP:0000007 "trophoblastic" xsd:string property_value: UBPROP:0000011 "The postimplantation derivatives of the trophectoderm, which make up most of the fetal part of the placenta" xsd:string {source="PMID:19829370"} [Term] id: UBERON:0000091 name: bilaminar disc namespace: uberon def: "A flattened, almost circular bilaminar plate of cells formed when the inner cell mass (aka embryoblast) forms two epithelial layers, each of a distinct lineage, separated by an extracellular basement membrane: the external (dorsal) layer is called the epiblast and the internal (ventral) layer is called the hypoblast (aka primitive endoderm); together, they compose the bilaminar embryonic disc." [MP:0003886] subset: early_development subset: pheno_slim synonym: "bilaminar disk" RELATED [Wikipedia:Bilaminar_disc] synonym: "bilaminary embryonic disc" EXACT [] synonym: "bilaminary germ disc" EXACT [ISBN:9780878932504] synonym: "embryonic disc" BROAD [MP:0003886] synonym: "embryonic shield" BROAD [MP:0003886] synonym: "germinal disc" BROAD [MP:0003886] synonym: "germinal disk" BROAD [MP:0003886] xref: FMA:293863 xref: NCIT:C34112 xref: UMLS:C1283997 {source="ncithesaurus:Bilaminar_Embryonic_Disc"} xref: Wikipedia:Bilaminar_disc is_a: UBERON:0002050 ! embryonic structure relationship: develops_from UBERON:0000087 {source="Wikipedia"} ! inner cell mass property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/e/e3/Gray21.png" xsd:anyURI [Term] id: UBERON:0000092 name: post-embryonic stage namespace: uberon def: "Stage succeeding embryo, including mature structure." [https://orcid.org/0000-0002-6601-2165] synonym: "post-hatching stage" NARROW [] synonym: "postembryonic" RELATED [] synonym: "postembryonic stage" EXACT [] xref: BilaDO:0000003 xref: OGES:000010 xref: OGES:000014 xref: OGES:000024 xref: WBls:0000022 xref: WBls:0000093 xref: WBls:0000103 is_a: UBERON:0000105 ! life cycle stage relationship: preceded_by UBERON:0000068 ! embryo stage relationship: simultaneous_with GO:0009791 ! post-embryonic development property_value: seeAlso "https://github.com/obophenotype/uberon/issues/344" xsd:anyURI property_value: UBPROP:0000008 "In birds, the postnatal stage begins when the beak penetrates the shell (i.e., external pipping) (Brown et al. 1997)" xsd:string [Term] id: UBERON:0000094 name: membrane organ namespace: uberon def: "Nonparenchymatous organ that primarily consists of dense connective tissue organized into a sheet which interconnects two or more organs, separates two or more body spaces from one another, or surrounds an organ or body part. Examples: interosseous membrane of forearm, obturator membrane, tympanic membrane, fibrous pericardium, fascia lata, dura mater. [FMA]." [FMA:7145] synonym: "membrane" BROAD [] synonym: "membrane of organ" EXACT [] xref: FMA:7145 is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000062 ! organ relationship: composed_primarily_of UBERON:0011823 {source="FMA-def"} ! dense connective tissue property_value: term:contributor https://orcid.org/0000-0002-6601-2165 creation_date: 2009-07-30T05:19:13Z [Term] id: UBERON:0000095 name: cardiac neural crest namespace: uberon def: "Portion of neural crest that develops from the dorsal neural tube. It overlaps the vagal neural crest and migrates to populate the pharyngeal arches 3, 4 and 6 (producing structures in the head) and to the heart, forming connective tissue that separates the great vessels of the heart. [Wikipedia]." [Wikipedia:Cardiac_neural_crest] subset: vertebrate_core synonym: "cardiac neural crest complex" RELATED [Wikipedia:Cardiac_neural_crest] synonym: "complexus cristae neuralis cardiacus" RELATED [Wikipedia:Cardiac_neural_crest] xref: TAO:0002173 xref: Wikipedia:Cardiac_neural_crest xref: XAO:0004190 xref: ZFA:0001648 is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0005291 ! embryonic tissue relationship: overlaps UBERON:0005428 {source="Wikipedia"} ! vagal neural crest relationship: part_of UBERON:0002342 ! neural crest property_value: term:contributor https://orcid.org/0000-0002-6601-2165 property_value: UBPROP:0000001 "A subpopulation of the cephalic neural crest that emerges from the otic level to the anterior limit of somite 4. It migrates to the heart and is essential for the septation of the outflow track[DOI:10.1242/dev.091751]." xsd:string {source="DOI:10.1242/dev.091751"} property_value: UBPROP:0000012 "ZFA treats this as a subtype of NC." xsd:string {external_ontology="ZFA"} creation_date: 2009-07-30T07:57:38Z [Term] id: UBERON:0000101 name: lobe of lung namespace: uberon def: "A lung lobe is one of the rounded projections that compose the lung[GO]." [GOC:GO] subset: pheno_slim synonym: "lung lobe" EXACT [] synonym: "pulminory lobe" EXACT [] synonym: "pulmonary lobe" EXACT [FMA:7311] xref: EMAPA:36281 xref: FMA:7311 xref: galen:LobeOfLung xref: MA:0003098 xref: NCIT:C34021 xref: SCTID:245524004 xref: UMLS:C0225752 {source="ncithesaurus:Lung_Lobe"} is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0009912 {source="FMA"} ! anatomical lobe relationship: contributes_to_morphology_of UBERON:0002048 ! lung relationship: part_of UBERON:0002048 ! lung [Term] id: UBERON:0000102 name: lung vasculature namespace: uberon def: "The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs[GO]." [GOC:GO] subset: pheno_slim synonym: "lung vascular network" EXACT [OBOL:automatic] synonym: "pulmonary vasculature" EXACT [FMA:73750] synonym: "vascular network of lung" EXACT [OBOL:automatic] synonym: "vasculature of lung" EXACT [OBOL:automatic] xref: FMA:73750 is_a: UBERON:0002201 ! vasculature of trunk is_a: UBERON:0006876 ! vasculature of organ intersection_of: UBERON:0002049 ! vasculature intersection_of: part_of UBERON:0002048 ! lung relationship: part_of UBERON:0002048 ! lung [Term] id: UBERON:0000104 name: life cycle namespace: uberon def: "An entire span of an organism's life. In metazoans, commences with the zygote stage and ends with the death of the organism." [https://orcid.org/0000-0002-6601-2165] subset: common_anatomy subset: upper_level synonym: "entire life cycle" EXACT [] synonym: "entire lifespan" EXACT [] synonym: "life" EXACT [] synonym: "lifespan" EXACT [] xref: FBdv:00000000 xref: HsapDv:0000001 xref: MmusDv:0000001 xref: ncithesaurus:Life xref: OGES:000011 is_a: UBERON:0000000 ! processual entity relationship: ends_with UBERON:0000071 ! death stage relationship: has_part UBERON:0000105 ! life cycle stage relationship: starts_with UBERON:0000106 {gci_relation="in_taxon", gci_filler="NCBITaxon:33208"} ! zygote stage property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 property_value: seeAlso "https://github.com/obophenotype/uberon/issues/532" xsd:anyURI [Term] id: UBERON:0000105 name: life cycle stage namespace: uberon def: "A spatiotemporal region encompassing some part of the life cycle of an organism." [https://orcid.org/0000-0002-6601-2165] subset: common_anatomy subset: efo_slim subset: upper_level synonym: "developmental stage" NARROW [] synonym: "stage" NARROW [] xref: BILS:0000105 xref: EFO:0000399 xref: FBdv:00007012 xref: FMA:24120 xref: HsapDv:0000000 xref: MESH:D008018 xref: MmusDv:0000000 xref: ncithesaurus:Developmental_Stage xref: OlatDv:0000010 xref: PdumDv:0000090 xref: WBls:0000002 xref: XAO:1000000 xref: ZFS:0000000 xref: ZFS:0100000 is_a: UBERON:0000000 ! processual entity relationship: part_of UBERON:0000104 ! life cycle property_value: editor_note "this class represents a proper part of the life cycle of an organism. The class 'life cycle' should not be placed here" xsd:string property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 property_value: UBPROP:0000012 "the WBls class 'all stages' belongs here as it is the superclass of other WBls stages" xsd:string property_value: UBPROP:0000012 "we map the ZFS unknown stage here as it is logically equivalent to saying *some* life cycle stage" xsd:string [Term] id: UBERON:0000106 name: zygote stage namespace: uberon def: "A stage at which the organism is a single cell produced by means of sexual reproduction." [Wikipedia:Zygote] subset: efo_slim synonym: "1-cell stage" EXACT [] synonym: "fertilized egg stage" EXACT [BTO:0000854] synonym: "fertilized egg stage" RELATED [] synonym: "one cell stage" EXACT [] synonym: "one-cell stage" RELATED [VHOG:0000745] synonym: "zygote" RELATED [VHOG:0000745] synonym: "zygotum" RELATED OMO:0003011 [Wikipedia:Zygote] xref: BilaDO:0000005 xref: BILS:0000106 xref: EFO:0001322 xref: EHDAA:27 xref: FBdv:00005288 xref: IDOMAL:0000302 {sssom:mapping_justification="vocab:ManualMappingCuration", sssom:author_id="https://orcid.org/0000-0003-4423-4370", sssom:mapping_provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C12601 xref: PdumDv:0000100 xref: VHOG:0000745 xref: Wikipedia:Zygote xref: XAO:1000001 xref: ZFS:0000001 is_a: UBERON:0000105 ! life cycle stage relationship: part_of UBERON:0000068 ! embryo stage relationship: seeAlso EMAPA:16033 relationship: starts UBERON:0000104 ! life cycle property_value: UBPROP:0000003 "As in all metazoans, eumetazoan development begins with a fertilized egg, or zygote.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000745", ontology="VHOG", source="ISBN:978-0030259821 Ruppert EE, Fox RS, Barnes RD, Invertebrate zoology: a functional evolutionary approach (2003) p.107", source="http://bgee.unil.ch/"} [Term] id: UBERON:0000107 name: cleavage stage namespace: uberon def: "The first few specialized divisions of an activated animal egg; Stage consisting of division of cells in the early embryo. The zygotes of many species undergo rapid cell cycles with no significant growth, producing a cluster of cells the same size as the original zygote. The different cells derived from cleavage are called blastomeres and form a compact mass called the morula. Cleavage ends with the formation of the blastula." [GO:0040016, Wikipedia:Cleavage_(embryo)] subset: efo_slim xref: BilaDO:0000006 xref: BILS:0000107 xref: EFO:0001290 xref: FBdv:00000054 xref: MESH:D002970 xref: MmusDv:0000004 xref: OGES:000015 xref: OGES:000020 xref: PdumDv:0000200 xref: Wikipedia:Cleavage_(embryo) xref: XAO:1000004 xref: ZFS:0000046 is_a: UBERON:0000105 ! life cycle stage intersection_of: UBERON:0000105 ! life cycle stage intersection_of: simultaneous_with GO:0040016 ! embryonic cleavage relationship: immediately_preceded_by UBERON:0000106 ! zygote stage relationship: part_of UBERON:0000068 ! embryo stage relationship: simultaneous_with GO:0040016 ! embryonic cleavage [Term] id: UBERON:0000108 name: blastula stage namespace: uberon def: "An early stage of embryonic development in animals. It is produced by cleavage of a fertilized ovum and consists of a spherical layer of around 128 cells surrounding a central fluid-filled cavity called the blastocoel. The blastula follows the morula and precedes the gastrula in the developmental sequence." [Wikipedia:Blastula] subset: efo_slim xref: BilaDO:0000007 xref: BILS:0000108 xref: EFO:0001282 xref: HsapDv:0000006 xref: MmusDv:0000007 xref: OGES:000003 xref: OGES:000016 xref: OGES:000021 xref: WBls:0000005 xref: Wikipedia:Blastula xref: XAO:1000003 xref: ZFS:0000045 is_a: UBERON:0000105 ! life cycle stage relationship: part_of UBERON:0000068 ! embryo stage relationship: preceded_by UBERON:0000107 ! cleavage stage property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/c/c6/Blastulation.png" xsd:anyURI property_value: editor_note "consider adding a preceding stage 'morula stage' as part of cleavage" xsd:string [Term] id: UBERON:0000109 name: gastrula stage namespace: uberon def: "A stage defined by complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm." [GO:0007369] subset: efo_slim synonym: "blastocystis trilaminaris stage" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "trilaminar blastocyst stage" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "trilaminar blastoderm stage" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "trilaminar disk stage" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "trilaminar germ stage" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "trilaminar stage" RELATED [https://orcid.org/0000-0002-6601-2165] xref: BilaDO:0000008 xref: BILS:0000109 xref: EFO:0001296 xref: FBdv:00005317 xref: HsapDv:0000010 xref: MmusDv:0000013 xref: OGES:000004 xref: OGES:000019 xref: WBls:0000010 xref: XAO:1000005 xref: ZFS:0000047 is_a: UBERON:0000105 ! life cycle stage relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of UBERON:0000068 ! embryo stage relationship: preceded_by UBERON:0000108 {source="BILS"} ! blastula stage relationship: simultaneous_with GO:0007369 ! gastrulation [Term] id: UBERON:0000110 name: neurula stage namespace: uberon def: "Staged defined by the formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system." [GO:0001841] xref: BilaDO:0000009 xref: BILS:0000110 xref: HsapDv:0000012 xref: MmusDv:0000017 xref: XAO:1000006 is_a: UBERON:0000105 ! life cycle stage relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of UBERON:0000068 ! embryo stage relationship: preceded_by UBERON:0000109 ! gastrula stage relationship: simultaneous_with GO:0001841 ! neural tube formation property_value: RO:0002174 NCBITaxon:7955 property_value: seeAlso "https://github.com/obophenotype/developmental-stage-ontologies/issues/84" xsd:anyURI property_value: seeAlso "https://github.com/obophenotype/uberon/issues/343" xsd:anyURI property_value: UBPROP:0000008 "In zebrafish, the times of neurulation and segmentation overlap so extensively there is no distinct neurula period of development, such as occurs largely before segmentation in amphibian embryos." xsd:string [Term] id: UBERON:0000111 name: organogenesis stage namespace: uberon def: "A stage at which the ectoderm, endoderm, and mesoderm develop into the internal organs of the organism." [Wikipedia:Organogenesis] synonym: "segmentation stage" RELATED [] xref: BilaDO:0000010 xref: BILS:0000111 xref: HsapDv:0000015 xref: MmusDv:0000018 xref: OGES:000005 xref: OGES:000032 xref: Wikipedia:Organogenesis is_a: UBERON:0000105 ! life cycle stage relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of UBERON:0000068 ! embryo stage relationship: preceded_by UBERON:0000110 {gci_relation="part_of", gci_filler="NCBITaxon:32523"} ! neurula stage relationship: simultaneous_with GO:0048513 ! animal organ development property_value: seeAlso "https://github.com/obophenotype/developmental-stage-ontologies/issues/84" xsd:anyURI property_value: seeAlso "https://github.com/obophenotype/uberon/issues/533" xsd:anyURI [Term] id: UBERON:0000112 name: sexually immature stage namespace: uberon subset: efo_slim synonym: "immature stage" EXACT [VHOG:FB] synonym: "juvenile stage" NARROW [XAO:1000010] synonym: "subadult stage" RELATED [http://eol.org/schema/terms/subadult] xref: BILS:0000112 xref: BTO:0002168 xref: EFO:0001300 xref: EV:0300051 xref: MmusDv:0000043 xref: OGES:000009 xref: XAO:1000010 xref: XtroDO:0000083 xref: ZFS:0000051 is_a: UBERON:0000105 ! life cycle stage relationship: part_of UBERON:0000066 ! fully formed stage relationship: preceded_by UBERON:0000069 {gci_relation="part_of", gci_filler="NCBITaxon:7955", source="ZFS"} ! larval stage property_value: seeAlso "https://github.com/obophenotype/uberon/issues/427" xsd:anyURI property_value: UBPROP:0000001 "The stage of being a sexually immature adult animal[XAO:1000010]." xsd:string {source="XAO:1000010"} property_value: UBPROP:0000008 "In mammals this would include infant (nourishment from lactation) and juvenile (prepubertal no longer dependent on mother)" xsd:string [Term] id: UBERON:0000113 name: post-juvenile adult stage namespace: uberon def: "The stage of being a sexually mature adult animal." [https://orcid.org/0000-0002-6601-2165] synonym: "adult stage" BROAD [] xref: BILS:0000113 xref: EV:0300064 xref: EV:0300070 xref: MIAA:0000403 xref: MmusDv:0000110 xref: OGES:000026 xref: OGES:000027 xref: XAO:1000093 xref: ZFS:0000044 is_a: UBERON:0000105 ! life cycle stage relationship: part_of UBERON:0000066 ! fully formed stage relationship: preceded_by UBERON:0000112 ! sexually immature stage property_value: seeAlso "https://github.com/obophenotype/uberon/issues/345" xsd:anyURI property_value: seeAlso "https://github.com/obophenotype/uberon/issues/499" xsd:anyURI [Term] id: UBERON:0000114 name: lung connective tissue namespace: uberon def: "The connective tissue located between the respiratory (airway and alveolar) epithelium, the capillary endothelium and pleural mesothelium; it contains basement membrane composed of collagen, elastin, proteoglycans, and fibronectin." [ISBN:0-683-40008-8, MGI:anna, MP:0002276, PMID:14635660] subset: human_reference_atlas subset: pheno_slim synonym: "connective tissue of lung" EXACT [OBOL:automatic] synonym: "lung interstitial tissue" RELATED [MA:0001782] synonym: "lung interstitium" RELATED [] synonym: "pulmonary connective tissue" RELATED [EMAPA:35521] synonym: "pulmonary interstitial tissue" RELATED [] synonym: "pulmonary interstitium" EXACT [FMA:27533] xref: EMAPA:35521 xref: FMA:27533 xref: MA:0001782 xref: SCTID:201609008 is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure is_a: UBERON:0003580 ! lower respiratory tract connective tissue is_a: UBERON:0003837 ! thoracic segment connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0002048 ! lung relationship: contributes_to_morphology_of UBERON:0002048 ! lung relationship: develops_from UBERON:0004883 ! lung mesenchyme relationship: part_of UBERON:0002048 ! lung relationship: transformation_of UBERON:0004883 ! lung mesenchyme property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000009 "it functions in the mechanical behavior of the lung, and forms a barrier to regulate the flow of plasma constituents from the capillaries to the airway and alveolar spaces" xsd:string [Term] id: UBERON:0000115 name: lung epithelium namespace: uberon def: "The epithelial layer of the lung." [MP:0006382] subset: pheno_slim synonym: "epithelial tissue of lung" EXACT [OBOL:automatic] synonym: "epithelium of lung" EXACT [OBOL:automatic] synonym: "lung epithelial tissue" EXACT [OBOL:automatic] synonym: "pulmonary epithelium" RELATED [BTO:0001653] xref: BTO:0001653 xref: EMAPA:32860 xref: MA:0001783 is_a: UBERON:0004815 ! lower respiratory tract epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002048 ! lung relationship: contributes_to_morphology_of UBERON:0002048 ! lung relationship: develops_from UBERON:0001041 ! foregut relationship: part_of UBERON:0002048 ! lung property_value: UBPROP:0000008 "A pseudostratified epithelium, containing basal cells, stem cells of the airway, submucosal glands and cartilage rings, is limited to the trachea and large lobar airways in the mouse (Morrisey and Hogan, 2010). This more complex epithelium extends to terminal bronchioles in the human[DOI:10.1242/dev.115469]" xsd:string [Term] id: UBERON:0000117 name: respiratory tube namespace: uberon def: "A tube in the respiratory system. Examples: bronchus, bronchiole, trachea." [GO:0030323, http://orcid.org/0000-0002-6601-2165] synonym: "airway" RELATED [] synonym: "respiratory conducting tube" NARROW [MP:0004391] synonym: "segment of tracheobronchial tree" EXACT [FMA:12224] synonym: "segment of tracheobronchial tree" NARROW [FMA:12224] synonym: "tracheobronchial tree segment" NARROW [FMA:12224] xref: EMAPA:37946 {source="MA:th"} xref: FMA:12224 is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000025 ! tube is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: UBERON:0000025 ! tube intersection_of: part_of UBERON:0000065 ! respiratory tract relationship: has_part UBERON:0000483 ! epithelium relationship: part_of UBERON:0000065 ! respiratory tract property_value: UBPROP:0000012 "in GO lung development is part of respiratory tube development. This can lead to inconsistencies with other ontologies, e.g. VT. The GO structure may be better represented by a tree of tubes (see the FMA class)" xsd:string {external_ontology="GO"} [Term] id: UBERON:0000118 name: lung bud namespace: uberon def: "Structure derived from foregut that becomes a lung[GO]." [GO:0060431, Wikipedia:Respiratory_bud] subset: pheno_slim synonym: "gemma pulmonalis" RELATED OMO:0003011 [Wikipedia:Lung_buds] synonym: "gemma respiratoria" RELATED OMO:0003011 [Wikipedia:Lung_buds] synonym: "lung bud" RELATED OMO:0003004 [] synonym: "primary lung bud" RELATED [GO:0060572] synonym: "respiratory diverticulum" RELATED [Wikipedia:Lung_buds] xref: BTO:0001643 xref: EHDAA2:0004089 xref: NCIT:C34260 xref: NCIT:C34282 xref: SCTID:361427007 xref: UMLS:C1514420 {source="ncithesaurus:Primary_Bronchial_Bud"} xref: UMLS:C1514897 {source="ncithesaurus:Respiratory_Diverticulum"} xref: Wikipedia:Respiratory_bud is_a: UBERON:0005153 {source="GO:0060441"} ! epithelial bud is_a: UBERON:0005911 ! endo-epithelium relationship: adjacent_to UBERON:0004872 ! splanchnic layer of lateral plate mesoderm relationship: develops_from UBERON:0005597 ! lung primordium relationship: develops_from UBERON:0008947 {source="EHDAA2"} ! respiratory primordium property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/7/71/Gray948.png" xsd:anyURI property_value: editor_note "clarify successors - include bronchi?" xsd:string [Term] id: UBERON:0000122 name: neuron projection bundle namespace: uberon alt_id: UBERON:0005163 def: "A fasciculated bundle of neuron projections (GO:0043005), largely or completely lacking synapses." [CARO:0001001, FBbt:00005099, FBC:DOS] synonym: "funiculus" EXACT [] synonym: "nerve fiber bundle" EXACT [FBbt:00005099] synonym: "neural fiber bundle" EXACT [] xref: CARO:0001001 xref: FBbt:00005099 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: NLX:147821 is_a: UBERON:0005162 ! multi cell part structure relationship: has_part GO:0043005 ! neuron projection relationship: part_of UBERON:0001016 ! nervous system [Term] id: UBERON:0000125 name: neural nucleus namespace: uberon def: "A spatially aggregated collection of nerve cell bodies in the CNS, consisting of one or more subpopulations that share cell type, chemical phenotype, and connections, and including nearby cells that share the same cell type, chemical phenotype, and connections. (CUMBO)." [NLX:28443] subset: cumbo synonym: "nervous system nucleus" EXACT [] synonym: "neuraxis nucleus" EXACT [FMA:83686] synonym: "neuronal nucleus" EXACT [AEO:0000136] synonym: "nucleus" BROAD [] synonym: "nucleus of CNS" EXACT [NLX:28443] synonym: "nucleus of neuraxis" RELATED [] xref: AEO:0000136 xref: FMA:83686 xref: NCIT:C13197 xref: NLX:28443 xref: Wikipedia:Nucleus_(neuroanatomy) is_a: UBERON:0011215 ! central nervous system cell part cluster relationship: composed_primarily_of UBERON:0002020 ! gray matter relationship: only_in_taxon NCBITaxon:7711 {notes="we limit this structure by definition to chordate and vertebrate nervous systems"} ! Chordata property_value: UBPROP:0000001 "Anatomical structure consisting of a discrete aggregate of neuronal soma[GO][GO_REF:0000021]." xsd:string {source="GO_REF:0000021"} property_value: UBPROP:0000012 "Proposed CUMBO def from MM: A subcortical part of the nervous system consisting of a relatively compact group of cells that is distinguishable histologically that share a commonality of cytoarchitecture, chemoarchitecturel and connectivity. (comments: I put in 'subcortical' because I don't think we consider either the cerebellar cortex or cerebral cortex to be nuclei. Some people distinguish between a nucleus and a laminar structure (see Wikipedia definition). However, there are structures identified as nuclei that are laminar, e.g., lateral geniculate nucleus, although they are not laminated in all species. Also, I put in 'relatively compact' and 'distiguishable by histology' because we have groups of cells, e.g., cholinergic cell groups, doparminergic cell groups that are related on the 3 criteria but which we don't tend to consider nuclei because they don't occupy an easily defined territory. But all is open to debate." xsd:string [Term] id: UBERON:0000126 name: cranial nerve nucleus namespace: uberon def: "Nucleus that receives projections from or contains neurons that send projections through one of the cranial nerves." [NLX:28532] synonym: "cranial neural nucleus" EXACT [FMA:54501] synonym: "nucleus nervi cranialis" RELATED OMO:0003011 [Wikipedia:Cranial_nerve_nucleus] synonym: "nucleus of cranial nerve" EXACT [] xref: EMAPA:37066 {source="MA:th"} xref: FMA:54501 xref: NLX:28532 xref: SCTID:280160003 xref: Wikipedia:Cranial_nerve_nucleus is_a: UBERON:0002308 ! nucleus of brain intersection_of: UBERON:0002308 ! nucleus of brain intersection_of: extends_fibers_into UBERON:0001785 ! cranial nerve relationship: extends_fibers_into UBERON:0001785 ! cranial nerve relationship: part_of RO:0002577 ! system property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/3/30/Gray696.png" xsd:anyURI [Term] id: UBERON:0000153 name: anterior region of body namespace: uberon is_a: UBERON:0000475 ! organism subdivision disjoint_from: UBERON:0000154 {source="lexical"} ! posterior region of body relationship: anterior_to UBERON:0000154 ! posterior region of body relationship: only_in_taxon NCBITaxon:33213 ! Bilateria [Term] id: UBERON:0000154 name: posterior region of body namespace: uberon is_a: UBERON:0000475 ! organism subdivision relationship: only_in_taxon NCBITaxon:33213 ! Bilateria [Term] id: UBERON:0000158 name: membranous layer namespace: uberon synonym: "membrane" BROAD [] synonym: "membranous organ component" EXACT [FMA:82500] xref: FMA:30322 xref: FMA:82500 xref: MESH:D008566 xref: NCIT:C12749 is_a: UBERON:0004923 ! organ component layer relationship: bounding_layer_of UBERON:0000064 ! organ part property_value: UBPROP:0000001 "A thin sheet or layer of pliable tissue, serving as a covering or envelope of a part, as the lining of a cavity, as a partition or septum, or to connect two structures." xsd:string {source="ncithesaurus:Membrane"} [Term] id: UBERON:0000159 name: anal canal namespace: uberon def: "The terminal part of the large intestine, continuous proximally with the rectum and distally terminates with the anus." [Wikipedia:Anal_canal] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "anal canal" EXACT [] synonym: "anal canal viewed anatomically" EXACT [] synonym: "anal pad" RELATED [] synonym: "anatomical anal canal" EXACT [] synonym: "anus" RELATED [] synonym: "canalis analis" RELATED OMO:0003011 [BTO:0001978, Wikipedia:Anal_canal] synonym: "cloaca" RELATED [] synonym: "cloacal chamber" RELATED [] synonym: "mesenteron" RELATED [] synonym: "pars analis recti" RELATED [BTO:0001978] xref: BTO:0001978 xref: CALOHA:TS-2160 xref: EMAPA:18256 xref: FMA:15703 xref: galen:AnalCanal xref: MA:0000330 xref: MESH:D001003 {sssom:mapping_justification="vocab:ManualMappingCuration", sssom:author_id="https://orcid.org/0000-0001-9439-5346", sssom:mapping_provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C12375 xref: SCTID:245438008 xref: UMLS:C0227411 {source="ncithesaurus:Anal_Canal"} xref: Wikipedia:Anal_canal is_a: UBERON:0004111 ! anatomical conduit is_a: UBERON:0004121 ! ectoderm-derived structure relationship: channel_for UBERON:0001988 ! feces relationship: continuous_with UBERON:0001052 ! rectum relationship: continuous_with UBERON:0001245 ! anus relationship: develops_from UBERON:0011272 {source="Wikipathways:WP2062"} ! embryonic skin basal layer relationship: part_of UBERON:0000059 ! large intestine relationship: part_of UBERON:0001353 ! anal region property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/0/01/Gray1078.png" xsd:anyURI property_value: editor_note "requires alignment with EHDAA2 and complete developmental relationships" xsd:string property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0000160 name: intestine namespace: uberon def: "Segment of the alimentary canal extending from the stomach to the anus and, in humans and other mammals, consists of two segments, the small intestine and the large intestine." [GOC:GO, Wikipedia:Intestine] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "bowel" EXACT [] synonym: "intestinal tract" RELATED [] xref: AAO:0000246 xref: ANISEED:1235303 xref: BSA:0000093 xref: BTO:0000648 xref: CALOHA:TS-0490 xref: EFO:0000834 xref: EMAPA:32874 xref: EV:0100071 xref: FMA:7199 xref: GAID:295 xref: galen:Intestine xref: MA:0000328 xref: MA:0001524 xref: MESH:D007422 xref: MIAA:0000043 xref: NCIT:C12736 xref: SCTID:256876008 xref: TAO:0001338 xref: UMLS:C0021853 {source="ncithesaurus:Intestine"} xref: VHOG:0000056 xref: WBbt:0005772 xref: Wikipedia:Intestine xref: XAO:0000129 xref: ZFA:0001338 is_a: UBERON:0004921 {source="cjm"} ! subdivision of digestive tract relationship: contributes_to_morphology_of UBERON:0001007 ! digestive system relationship: part_of UBERON:0005409 ! alimentary part of gastrointestinal system property_value: editor_note "This class is probably too inclusive" xsd:string property_value: UBPROP:0000001 "Portion of the alimentary canal bounded anteriorly by the pyloric sphincter and posteriorly by the cloacal sphincter.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000246", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000001 "The tract of the alimentary canal. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000056", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "intestinal" xsd:string property_value: UBPROP:0000008 "In zebrafish, No stomach, small intestine, or large intestine can be distinguished. However, differences can be found in the morphology of the mucosa columnar epithelial cells and the number of goblet cells, suggesting functional differentiation. The intestine has numerous folds that become progressively shorter in a rostral-to-caudal direction. Proportionally, these folds are significantly larger than the finger-like intestinal villi of mammals and other amniotes (Wallace et al. 2005). Columnar-shaped absorptive enterocytes are the most numerous in the zebrafish intestinal epithelium. Goblet cells are the second most populous epithelial cell type." xsd:string [Term] id: UBERON:0000161 name: orifice namespace: uberon def: "Anatomical conduit that connects two adjacent body spaces (or a body space with the space surrounding the organism)[FMA,modified]." [FMA:3724] synonym: "anatomical orifice" EXACT [FMA:3724] synonym: "anatomical ostium" BROAD [FMA:3724] synonym: "hilum" NARROW [] synonym: "ostium" BROAD [] xref: FMA:3724 xref: SCTID:91837002 is_a: UBERON:0004111 ! anatomical conduit property_value: UBPROP:0000012 "in FMA, this is an anatomical conduit *space*, rather than anatomical conduit" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0000162 name: cloaca namespace: uberon def: "Common chamber into which the intestines and excretory system opens. Arises during development in all vertebrates, but in many it becomes subdivided, lost or incorporated into other structures." [ISBN:0073040584, Wikipedia:Cloaca] synonym: "cloacal chamber" RELATED [AAO:0000095] synonym: "vent" RELATED [XAO:0000244] xref: AAO:0000095 xref: GAID:1206 xref: MESH:D002988 xref: NCIT:C34127 xref: SCTID:362857006 xref: SCTID:370631000 xref: UMLS:C0008987 {source="ncithesaurus:Cloaca"} xref: VHOG:0001186 xref: Wikipedia:Cloaca xref: XAO:0000244 xref: ZFA:0005781 is_a: UBERON:0013522 ! subdivision of tube relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0001555 {source="ZFA"} ! digestive tract relationship: part_of UBERON:0004122 {source="AAO"} ! genitourinary system property_value: editor_note "adding df link to embryonic cloaca leads to a cycle in uberon-simple, as cloaca is a suberclass of embryonic cloaca" xsd:string property_value: RO:0002175 NCBITaxon:9369 {notes="most adult placentals have no trace of a cloaca. However, the tenrecs and golden moles, small placental mammals native to Africa, retain a cloaca as adults."} property_value: UBPROP:0000001 "A common passage for fecal, urinary, and reproductive discharge in most lower vertebrates as well as the terminal end of the hindgut before division into rectum, bladder, and genital primordia in mammalian embryos. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001186", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/cloaca"} property_value: UBPROP:0000001 "Anatomical structure which is the common receptacle for the alimentary canal, Wolffian ducts, oviducts, and the bladder.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000095", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000003 "A cloaca is apparently a primitive vertebrate feature because it occurs in most primitive gnathostomes and persists in the embryos of almost all vertebrates.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001186", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.572", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "cloacal" xsd:string property_value: UBPROP:0000008 "Human beings only have an embryonic cloaca, which is split up into separate tracts during the development of the urinary and reproductive organs" xsd:string property_value: UBPROP:0000011 "hindgut endoderm and proctodeal ectoderm." xsd:string {source="WP"} [Term] id: UBERON:0000163 name: embryonic cloaca namespace: uberon def: "Endoderm-lined chamber that develops as pouch-like dilation of the caudal end of the hindgut and receives the allantois ventrally and two mesonephric ducts laterally; caudally it ends blindly at the cloacal membrane formed by the union of proctodeal (anal pit) ectoderm and cloacal endoderm, with no intervening mesoderm[MP]." [MP:0010115, Wikipedia:Cloaca_(embryology)] subset: pheno_slim synonym: "cloaca" RELATED SENSU [] xref: EHDAA2:0000256 xref: EHDAA:4895 xref: EMAPA:27573 xref: Wikipedia:Cloaca_(embryology) is_a: UBERON:0000162 ! cloaca relationship: has_developmental_contribution_from UBERON:0003064 ! intermediate mesoderm relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0001008 {source="EHDAA2"} ! renal system relationship: part_of UBERON:0012361 {source="EHDAA2"} ! internal anal region property_value: curator_notes "this class represents the embryonic form of the cloaca, as found in both mammals and non-mammals." xsd:string [Term] id: UBERON:0000164 name: primitive urogenital sinus namespace: uberon def: "The ventral part of the cloaca remaining after septation of the rectum, which further develops into part of the bladder, part of the prostatic part of the male urethra and the urethra and vestibule in females." [ISBN:0-683-40008-8, MP:0010116] subset: pheno_slim synonym: "fetal UGS" EXACT [PMID:18977204] synonym: "sinus urogenitalis" EXACT OMO:0003011 [] synonym: "UGS" EXACT [MP:0010116] synonym: "urogenital sinus" BROAD [MP:0010116] xref: EHDAA2:0004060 xref: EHDAA:5029 xref: EHDAA:5919 xref: EMAPA:17379 xref: NCIT:C34322 xref: SCTID:50961009 xref: UMLS:C0231057 {source="ncithesaurus:Urogenital_Sinus"} xref: VHOG:0000414 xref: Wikipedia:Definitive_urogenital_sinus is_a: UBERON:0002050 ! embryonic structure relationship: contributes_to_morphology_of UBERON:0000163 ! embryonic cloaca relationship: develops_from UBERON:0003064 ! intermediate mesoderm relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0000163 {source="MP-def"} ! embryonic cloaca property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/6/6d/Gray1109.png" xsd:anyURI property_value: UBPROP:0000001 "The ventral part of the cloaca after its separation from the rectum, giving rise to the lower part of the bladder in both sexes, to the prostatic portion of the male urethra, and to the urethra and vestibule in the female. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000414", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/urogenital+sinus"} property_value: UBPROP:0000003 "In mammals the lowly monotremes still have a cloaca. Higher types have done away with this structure and have a separate anal outlet for the rectum. The monotreme cloaca shows the initiation of this subdivision. The cloaca has such includes only the distal part, roughly comparable to the proctodeum. The more proximal part is divided into (1) a large dorsal passage into which the intestine opens, the coprodeum, and (2) a ventral portion, the urodeum with which the bladder connects. (...) the development of the placental mammals recapitulates in many respects the phylogenetic story. In the sexually indifferent stage of placental mammal there is a cloaca. While the indifferent stage still persists, a septum develops, and extends out to the closing membrane. This divides the cloaca into two chambers: a coprodeum continuous with the gut above, and a urodeum or urogenital sinus below.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000414", ontology="VHOG", source="ISBN:978-0721676678 Romer AS, Vertebrate body (1970)p.388-89 and Figure 300", source="http://bgee.unil.ch/"} property_value: UBPROP:0000013 "the term 'urogenital sinus' may refer to the primitive urogenital sinus present as a transient developmental structure in most mammals or it may refer to a condition in which an unseptated cloaca persists in animals longer than normal" xsd:string {source="MP"} [Term] id: UBERON:0000165 name: mouth namespace: uberon def: "The proximal portion of the digestive tract, containing the oral cavity and bounded by the oral opening. In vertebrates, this extends to the pharynx and includes gums, lips, tongue and parts of the palate. Typically also includes the teeth, except where these occur elsewhere (e.g. pharyngeal jaws) or protrude from the mouth (tusks)." [https://github.com/obophenotype/uberon/wiki/The-digestive-tract, Wikipedia:Mouth] subset: efo_slim subset: major_organ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "adult mouth" NARROW [] synonym: "cavital oralis" RELATED OMO:0003011 [Wikipedia:Mouth] synonym: "cavitas oris" RELATED [BTO:0001090] synonym: "cavum oris" RELATED [BTO:0001090] synonym: "mouth cavity" RELATED [BTO:0001090] synonym: "oral region" RELATED [EHDAA2:0001326] synonym: "oral vestibule" RELATED [BTO:0001090] synonym: "regio oralis" EXACT OMO:0003011 [BTO:0004698, FMA:49184, FMA:TA] synonym: "rima oris" RELATED [BTO:0001090] synonym: "stoma" RELATED [] synonym: "stomatodaeum" RELATED [VHOG:0000812] synonym: "trophic apparatus" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "vestibule of mouth" RELATED [BTO:0001090] synonym: "vestibulum oris" RELATED [BTO:0001090] xref: AAO:0010355 xref: BTO:0001090 xref: BTO:0004698 xref: CALOHA:TS-1315 xref: EFO:0000825 xref: EHDAA2:0001326 xref: EHDAA:542 xref: EMAPA:16262 xref: FBbt:00003126 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:49184 xref: GAID:75 xref: galen:Mouth xref: http://purl.obolibrary.org/obo/uberon/images/lamprey_sucker_rosava_3238889218.jpg xref: MA:0000341 xref: MA:0002474 xref: MAT:0000038 xref: MESH:D009055 xref: MIAA:0000038 xref: SCTID:21082005 xref: TADS:0000040 xref: TAO:0000547 xref: TAO:0000590 xref: TGMA:0000131 xref: VHOG:0000280 xref: VHOG:0000812 xref: Wikipedia:Mouth xref: XAO:0003029 xref: ZFA:0000547 xref: ZFA:0000590 is_a: UBERON:0004921 {notes="the mouth contains structures such as jaw skeleton that may not strictly be considered tract parts"} ! subdivision of digestive tract intersection_of: UBERON:0004921 ! subdivision of digestive tract intersection_of: proximalmost_part_of UBERON:0001555 ! digestive tract relationship: develops_from UBERON:0035804 ! future mouth relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa relationship: proximalmost_part_of UBERON:0001555 ! digestive tract property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/0/06/Mouth_illustration-Otis_Archives.jpg" xsd:anyURI property_value: seeAlso "https://github.com/obophenotype/uberon/issues/661" xsd:anyURI property_value: UBPROP:0000001 "Cavity in which food is initially ingested and generally contains teeth, tongue and glands.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010355", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000003 "Molecular and developmental cell lineage data suggest that the acoel mouth opening is homologous to the mouth of protostomes and deuterostomes and that the last common ancestor of the Bilateria (the 'urbilaterian') had only this single digestive opening.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000812", ontology="VHOG", source="DOI:10.1038/nature07309 Hejnol A, Martindale MQ, Acoel development indicates the independent evolution of the bilaterian mouth and anus. Nature (2008)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "oral" xsd:string property_value: UBPROP:0000011 "some AOs place this as developing from the stomodeum but we weaken this to developmental contribution, as the mouth includes non-ectodermal derivatives" xsd:string property_value: UBPROP:0000012 "in FMA, the tongue, palate etc are part of the mouth which is itself a subdivision of the face. ZFA includes a separate class 'oral region' which is part of the mouth, but excludes tongue and lips" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0000166 name: oral opening namespace: uberon def: "The orifice that connects the mouth to the exterior of the body." [https://github.com/obophenotype/uberon/wiki/The-digestive-tract] subset: uberon_slim subset: vertebrate_core synonym: "mouth" RELATED INCONSISTENT [] synonym: "oral fissure" EXACT [FMA:59806] synonym: "oral orifice" EXACT [FMA:59806] synonym: "oral part of face" RELATED [] xref: FMA:59806 is_a: UBERON:0000161 {source="FMA"} ! orifice relationship: overlaps UBERON:0001004 {gci_relation="part_of", gci_filler="NCBITaxon:32523"} ! respiratory system relationship: part_of UBERON:0000165 ! mouth property_value: UBPROP:0000003 "(...) mouth development is very similar in protostomes and 'basal' deuterostomes, whereas the chordate mouth seems to develop at a new position. Recent data for echinoderms and hemichordates further suggest that this change in mouth position may result from change in the influence of a conserved ectodermal patterning system on mouth development. It has been suggested that the mouths of vertebrates and urochordates may constitute a 'new' mouth.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000280", ontology="VHOG", source="DOI:10.1016/j.semcdb.2007.06.002 Christiaen L, Jaszczyszyn Y, Kerfant M, Kanob S, Thermes V, Joly JS, Evolutionary modification of mouth position in deuterostomes. Seminars in Cell and Developmental Biology (2007)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0000167 name: oral cavity namespace: uberon def: "Anatomical cavity at the start of the digestive tract that that is enclosed by the mouth. The boundaries and contents vary depending on the species. In vertebrates, the boundaries are the oral opening, the cheeks, the palate and (if present) the palatoglossal arch - if this is not present then the mouth and pharynx form the oropharyngeal cavity. The buccal cavity contains the teeth, tongue and palate (when present)." [https://github.com/obophenotype/uberon/wiki/The-digestive-tract, https://orcid.org/0000-0002-6601-2165, ISBN:0073040584] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "bucca" RELATED [] synonym: "buccal cavity" EXACT [FMA:20292, ISBN:0073040584] synonym: "cavity of mouth" EXACT [] xref: AAO:0000053 xref: AAO:0000960 xref: BSA:0000107 xref: CALOHA:TS-1315 xref: EFO:0001975 xref: EHDAA2:0001324 xref: EHDAA:6970 xref: EMAPA:17411 xref: EMAPA:18399 xref: EV:0100057 xref: FMA:20292 xref: HAO:0000669 xref: MESH:D009055 {sssom:mapping_provider="https://github.com/biopragmatics/biomappings", sssom:mapping_justification="vocab:LexicalMatching"} xref: NCIT:C12421 xref: SCTID:181220002 xref: TAO:0001027 xref: TGMA:0000102 xref: UMLS:C0226896 {source="ncithesaurus:Oral_Cavity"} xref: VHOG:0000188 xref: WBbt:0005255 xref: XAO:0000126 xref: ZFA:0001027 is_a: UBERON:0002553 ! anatomical cavity intersection_of: UBERON:0000464 ! anatomical space intersection_of: luminal_space_of UBERON:0000165 ! mouth relationship: contributes_to_morphology_of UBERON:0000165 ! mouth relationship: luminal_space_of UBERON:0000165 ! mouth relationship: part_of UBERON:0000165 ! mouth property_value: UBPROP:0000001 "Anatomical cavity bounded anteriorly by the mouth and posteriorly by the derivatives of the branchial arches.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000960", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000001 "The cavity of the mouth, bounded by the jaw bones and associated structures (muscles and mucosa). [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000188", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/oral+cavity"} property_value: UBPROP:0000003 "Echinoderms, hemichordates, and chordates are called deuterostomes because the mouth arises not from the blastopore but from a second invagination at the anterior end of the larva that pushes in to connect with the archenteron.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000188", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.32", source="http://bgee.unil.ch/"} [Term] id: UBERON:0000168 name: proximal-distal subdivision of colon namespace: uberon def: "A section dividing a colon along a proximal-distal axis." [http://orcid.org/0000-0002-6601-2165] subset: non_informative synonym: "segment of colon" RELATED [FMA:222905] xref: FMA:222905 is_a: UBERON:0004921 {order="4", source="cjm"} ! subdivision of digestive tract intersection_of: UBERON:0013522 ! subdivision of tube intersection_of: subdivision_of UBERON:0001155 ! colon relationship: part_of UBERON:0001155 ! colon relationship: subdivision_of UBERON:0001155 ! colon [Term] id: UBERON:0000170 name: pair of lungs namespace: uberon def: "The pair of anatomical structures comprised of a left lung and right lung." [http://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas subset: pheno_slim synonym: "lungs" EXACT [] synonym: "lungs pair" EXACT [] synonym: "pulmones" EXACT OMO:0003011 [FMA:68877, FMA:TA] synonym: "set of lungs" EXACT [] xref: FMA:68877 is_a: UBERON:0034925 ! anatomical collection intersection_of: UBERON:0034925 ! anatomical collection intersection_of: has_member UBERON:0002167 ! right lung intersection_of: has_member UBERON:0002168 ! left lung relationship: has_member UBERON:0002167 ! right lung relationship: has_member UBERON:0002167 {cardinality="1"} ! right lung relationship: has_member UBERON:0002168 ! left lung relationship: has_member UBERON:0002168 {cardinality="1"} ! left lung relationship: located_in UBERON:0002224 ! thoracic cavity relationship: part_of UBERON:0001558 {source="FMA-abduced"} ! lower respiratory tract property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0000171 name: respiration organ namespace: uberon def: "Organ that functions in gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms." [GO:0007585] subset: functional_classification subset: organ_slim synonym: "apparatus respiratorius organ" EXACT [OBOL:automatic] synonym: "breathing organ" EXACT [] synonym: "gas exchange organ" RELATED [] synonym: "organ of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "organ of respiratory system" EXACT [OBOL:automatic] synonym: "respiratory organ" EXACT [] synonym: "respiratory system organ" EXACT [OBOL:automatic] xref: EMAPA:17607 xref: SCTID:272626006 xref: SPD:0000428 xref: TGMA:0001247 is_a: UBERON:0000062 ! organ intersection_of: UBERON:0000062 ! organ intersection_of: capable_of GO:0007585 ! respiratory gaseous exchange by respiratory system relationship: capable_of GO:0007585 ! respiratory gaseous exchange by respiratory system relationship: part_of UBERON:0001004 ! respiratory system [Term] id: UBERON:0000174 name: excreta namespace: uberon alt_id: UBERON:0000324 alt_id: UBERON:0007550 def: "A portion of organism substance that is the product of an excretion process that will be eliminated from the body. An excretion process is elimination by an organism of the waste products that arise as a result of metabolic activity." [GO:0007588, http://orcid.org/0000-0002-6601-2165] synonym: "excreted substance" EXACT [] synonym: "excretion" RELATED [BTO:0000491] synonym: "portion of excreted substance" EXACT [FMA:9674] synonym: "waste substance" EXACT [AEO:0000184] xref: AEO:0000184 xref: BTO:0000491 xref: EHDAA2_RETIRED:0003184 xref: ENVO:02000022 xref: FMA:9674 xref: galen:Excretion is_a: UBERON:0000463 ! organism substance intersection_of: UBERON:0000463 ! organism substance intersection_of: output_of GO:0007588 ! excretion relationship: output_of GO:0007588 ! excretion [Term] id: UBERON:0000178 name: blood namespace: uberon def: "A fluid that is composed of blood plasma and erythrocytes." [FMA:9670, http://orcid.org/0000-0002-6601-2165, https://github.com/obophenotype/uberon/issues/9, Wikipedia:Blood] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "portion of blood" EXACT [] synonym: "vertebrate blood" EXACT [] synonym: "whole blood" RELATED [BTO:0000089] xref: AAO:0000046 xref: BTO:0000089 xref: CALOHA:TS-0079 xref: EFO:0000296 xref: EHDAA2:0000176 xref: EHDAA:418 xref: EMAPA:16332 xref: ENVO:02000027 xref: EV:0100047 xref: FMA:9670 xref: GAID:965 xref: galen:Blood xref: MA:0000059 xref: MESH:D001769 xref: MIAA:0000315 xref: NCIT:C12434 xref: TAO:0000007 xref: UMLS:C0005767 {source="ncithesaurus:Blood"} xref: VHOG:0000224 xref: Wikipedia:Blood xref: XAO:0000124 xref: ZFA:0000007 is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000179 ! haemolymphatic fluid relationship: develops_from UBERON:0006596 ! presumptive blood relationship: has_part CL:0000232 {source="CL:tm"} ! erythrocyte relationship: has_part UBERON:0001969 ! blood plasma relationship: immediate_transformation_of UBERON:0006596 {source="Bgee:AN"} ! presumptive blood relationship: located_in UBERON:0002049 {source="https://github.com/obophenotype/uberon/issues/1330"} ! vasculature relationship: part_of UBERON:0002390 ! hematopoietic system property_value: curator_notes "This class excludes blood analogues, such as the insect analog of blood. See UBERON:0000179 haemolymphatic fluid." xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "A complex mixture of cells suspended in a liquid matrix that delivers nutrients to cells and removes wastes. (Source: BioGlossary, www.Biology-Text.com)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000007", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "Highly specialized circulating tissue consisting of several types of cells suspended in a fluid medium known as plasma.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000046", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000002 "relationship loss: subclass specialized connective tissue (AAO:0000571)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000046", ontology="AAO"} property_value: UBPROP:0000003 "Recent findings strongly suggest that the molecular pathways involved in the development and function of blood cells are highly conserved among vertebrates and various invertebrates phyla. (...) There is now good reason to believe that, in vertebrates and invertebrates alike, blood cell lineages diverge from a common type of progenitor cell, the hemocytoblast.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000224", ontology="VHOG", source="DOI:10.1146/annurev.cellbio.22.010605.093317 Hartenstein V, Blood cells and blood cell development in the animal kingdom. Annual review of cell and developmental biology (2006) ", source="http://bgee.unil.ch/"} property_value: x_1.1:contributor https://github.com/cmungall property_value: x_1.1:contributor https://github.com/tmeehan [Term] id: UBERON:0000179 name: haemolymphatic fluid namespace: uberon def: "Circulating fluid that is part of the hemolymphoid system. Blood, lymph, interstitial fluid or its analogs." [http://orcid.org/0000-0002-6601-2165] synonym: "blood or blood analog" RELATED [] synonym: "circulating fluid" RELATED [] xref: CARO:0000081 is_a: UBERON:0006314 ! bodily fluid intersection_of: UBERON:0000463 ! organism substance intersection_of: part_of UBERON:0002193 ! hemolymphoid system relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of UBERON:0002193 ! hemolymphoid system property_value: term:contributor https://orcid.org/0000-0002-6601-2165 creation_date: 2009-04-08T04:38:19Z [Term] id: UBERON:0000209 name: tetrapod frontal bone namespace: uberon def: "The bone forming the forehead and roof of the eye orbit." [ISBN:0-683-40008-8, MP:0000107, PMID:7914451, Wikipedia:Frontal_bone] subset: human_reference_atlas subset: pheno_slim synonym: "frontal" NARROW [AAO:0000206] synonym: "frontal bone" NARROW SENSU [FMA:52734, MA:0001466] synonym: "os frontal" NARROW SENSU [Wikipedia:Frontal_bone] synonym: "os frontale" RELATED OMO:0003011 [Wikipedia:Frontal_bone] xref: AAO:0000206 xref: EMAPA:19016 xref: FMA:52734 xref: GAID:226 xref: MA:0001466 xref: MESH:D005624 xref: NCIT:C32635 xref: SCTID:181793006 xref: UMLS:C0016732 {source="ncithesaurus:Frontal_Bone"} xref: VHOG:0001324 xref: VSAO:0000208 xref: Wikipedia:Frontal_bone is_a: UBERON:0002514 ! intramembranous bone is_a: UBERON:0008907 ! dermal bone is_a: UBERON:0010428 {source="FMA"} ! flat bone is_a: UBERON:0011164 ! neurocranium bone relationship: connected_to UBERON:0001677 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! sphenoid bone relationship: connected_to UBERON:0001679 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! ethmoid bone relationship: overlaps UBERON:0001697 ! orbit of skull relationship: part_of UBERON:0003113 {source="cjm"} ! dermatocranium property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/9/97/Gray136.png" xsd:anyURI property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/5/5b/Frontal_bone.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000008 "fused in humans, paired in other animals" xsd:string property_value: UBPROP:0000011 "In the mouse the parietal originates from cephalic paraxial mesoderm (Jiang 2000; Morriss-Kay 2001), whereas in the chicken it is traced back to either mesodermal (Noden 1978) or neural crest (Couly 1992, 1993)." xsd:string [Term] id: UBERON:0000211 name: ligament namespace: uberon def: "Dense regular connective tissue connecting two or more adjacent skeletal elements or supporting an organ." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, VSAO:0000073] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "ligament organ" EXACT [FMA:21496] xref: CALOHA:TS-2145 xref: EFO:0001966 xref: EMAPA:35493 xref: FMA:21496 xref: FMA:30319 xref: galen:Ligament xref: MA:0000113 xref: MESH:D008022 xref: NCIT:C13046 xref: SCTID:182358004 xref: TAO:0001682 xref: UMLS:C0023685 {source="ncithesaurus:Ligament"} xref: VHOG:0001272 xref: Wikipedia:Ligament xref: XAO:0004031 xref: ZFA:0001675 is_a: UBERON:0000062 ! organ relationship: has_part UBERON:0002384 ! connective tissue relationship: only_in_taxon NCBITaxon:33213 ! Bilateria property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/9/9a/Knee_diagram.svg" xsd:anyURI property_value: UBPROP:0000001 "Nonparenchymatous organ that primarily consists of dense connective tissue aggregated into fasciculi by connective tissue. Examples: sutural ligament, radiate sternocostal ligament, ligament of liver, ovarian ligament[FMA][FMA:21496]." xsd:string {source="FMA:21496"} property_value: UBPROP:0000001 "Portion of connective tissue that connects bone or cartilage.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001682", ontology="TAO", source="TAO:wd"} property_value: UBPROP:0000003 "Compared with their Ediacarian predecessor, Cambrian animals in general were characterized by their much stouter bodies. The stoutness of the body is likely due to the formation of ligaments and tendons, which in turn requires the crosslinking of collagen triple helices.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001272", ontology="VHOG", source="PMID:8710894 Ohno S, The notion of the Cambrian pananimalia genome. PNAS (1996)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "this groups both skeletal and non-skeletal ligaments. What is called a 'ligament' in many AOs is actually a skeletal ligament" xsd:string [Term] id: UBERON:0000219 name: vertebral foramen of atlas namespace: uberon synonym: "vertebral foramen of cervical vertebra 1" EXACT [] xref: FMA:24293 xref: SCTID:281228008 xref: Wikipedia:Atlas_(anatomy)#Vertebral_foramen is_a: UBERON:0001131 ! vertebral foramen is_a: UBERON:0005744 ! bone foramen intersection_of: UBERON:0001131 ! vertebral foramen intersection_of: part_of UBERON:0001092 ! vertebral bone 1 relationship: part_of UBERON:0001092 ! vertebral bone 1 [Term] id: UBERON:0000220 name: atlanto-occipital joint namespace: uberon def: "The Atlanto-occipital joint (articulation between the atlas and the occipital bone) consists of a pair of condyloid joints. The atlanto-occipital joint is a synovial joint. The ligaments connecting the bones are: Two Articular capsules; Posterior atlantoöccipital membrane; Anterior atlantoöccipital membrane; Lateral atlantoöccipital." [Wikipedia:Atlanto-occipital_joint] synonym: "articulatio atlanto-occipitalis" EXACT [FMA:24939] synonym: "articulatio atlantooccipitalis" RELATED OMO:0003011 [Wikipedia:Atlanto-occipital_joint] synonym: "atlanto occipital joint" EXACT [] synonym: "atlantooccipital joint" EXACT [] synonym: "craniovertebral joint" EXACT [FMA:24939] synonym: "occipito atlantal joint" EXACT [] synonym: "occipito-atlantal joint" EXACT [] xref: FMA:24939 xref: MESH:D001269 {sssom:mapping_justification="vocab:ManualMappingCuration", sssom:author_id="https://orcid.org/0000-0001-9439-5346", sssom:mapping_provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C32158 xref: ncithesaurus:Atlanto-occipital_Joint-Atlanto xref: SCTID:361831006 xref: UMLS:C0004169 {source="ncithesaurus:Atlanto-occipital_Joint"} xref: Wikipedia:Atlanto-occipital_joint is_a: UBERON:0002217 ! synovial joint is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0002217 ! synovial joint intersection_of: connects UBERON:0001092 ! vertebral bone 1 intersection_of: connects UBERON:0001676 ! occipital bone relationship: connects UBERON:0001092 ! vertebral bone 1 relationship: connects UBERON:0001676 ! occipital bone relationship: in_lateral_side_of UBERON:0006072 {source="FMA-abduced-lr"} ! cervical region of vertebral column relationship: part_of UBERON:0006072 ! cervical region of vertebral column property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/d/d4/Gray304.png" xsd:anyURI [Term] id: UBERON:0000304 name: tendon sheath namespace: uberon def: "A layer of membrane around a tendon. It has 2 layers: synovial sheath + fibrous tendon sheath." [Wikipedia:Tendon_sheath] synonym: "synovial tendon sheath" EXACT [FMA:45087] synonym: "vagina tendinis" RELATED OMO:0003011 [Wikipedia:Tendon_sheath] xref: BTO:0000051 xref: FMA:45087 xref: FMA:76715 xref: NCIT:C96299 xref: SCTID:361885006 xref: UMLS:C0224856 {source="ncithesaurus:Tendon_Sheath"} xref: Wikipedia:Tendon_sheath is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0004923 ! organ component layer intersection_of: UBERON:0004923 ! organ component layer intersection_of: bounding_layer_of UBERON:0000043 ! tendon relationship: bounding_layer_of UBERON:0000043 ! tendon relationship: has_part UBERON:0011233 ! synovial membrane of synovial tendon sheath relationship: has_part UBERON:0011234 ! fibrous membrane of synovial tendon sheath relationship: part_of UBERON:0000043 ! tendon property_value: editor_note "TODO - add layer relations. 'tendon sheath' GAT in FMA." xsd:string [Term] id: UBERON:0000307 name: blastula namespace: uberon alt_id: UBERON:0007011 def: "Organism at the blastula stage - an early stage of embryonic development in animals. It is produced by cleavage of a fertilized ovum and consists of a spherical layer of around 128 cells surrounding a central fluid-filled cavity called the blastocoel. The blastula follows the morula and precedes the gastrula in the developmental sequence." [Wikipedia:Blastula] subset: inconsistent_with_fma synonym: "blastosphere" RELATED [Wikipedia:Blastula] synonym: "blastula embryo" EXACT [BILA:0000059] xref: BILA:0000059 xref: BTO:0000128 xref: GAID:1294 xref: MESH:D036703 xref: OGEM:000006 xref: Wikipedia:Blastula is_a: UBERON:0000922 ! embryo intersection_of: UBERON:0000468 ! multicellular organism intersection_of: existence_starts_and_ends_during UBERON:0000108 ! blastula stage relationship: develops_from UBERON:0007010 ! cleaving embryo relationship: existence_starts_and_ends_during UBERON:0000108 ! blastula stage property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/c/c6/Blastulation.png" xsd:anyURI property_value: editor_note "TODO - check relationship with epiblast. Note in FMA this is not a subclass of embryo, but in uberon embryo is the whole organism from zygote onwards and thus includes the blastula" xsd:string [Term] id: UBERON:0000317 name: colonic mucosa namespace: uberon alt_id: UBERON:0003347 alt_id: UBERON:0004981 def: "Mucosa that is part of a colon. The mucosa of the colon is lined by a simple columnar epithelium with a thin brush border and numerous goblet cells." [http://orcid.org/0000-0002-6601-2165] subset: efo_slim subset: human_reference_atlas synonym: "colon mucosa" EXACT [FMA:14984] synonym: "colon mucous membrane" EXACT [OBOL:automatic] synonym: "colonic mucosa" EXACT [] synonym: "colonic mucous membrane" EXACT [FMA:14984] synonym: "large bowel mucosa" EXACT [OBOL:automatic] synonym: "mucosa of colon" EXACT [FMA:14984] synonym: "mucosa of large bowel" EXACT [OBOL:automatic] xref: BTO:0000271 xref: CALOHA:TS-0164 xref: EFO:0003038 xref: EMAPA:27375 xref: FMA:14984 xref: FMA:85388 xref: MA:0003194 xref: SCTID:362157008 is_a: UBERON:0001207 ! mucosa of large intestine intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001155 ! colon relationship: part_of UBERON:0001155 ! colon property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0000320 name: duodenal mucosa namespace: uberon alt_id: UBERON:0003348 def: "A mucosa that is part of a duodenum [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas synonym: "doudenal mucosa" EXACT [FMA:14942] synonym: "duodenal mucous membrane" EXACT [FMA:14942] synonym: "duodenum mucosa" RELATED [BTO:0000367] synonym: "mucosa of duodenum" EXACT [OBOL:automatic] synonym: "mucous membrane of duodenum" EXACT [OBOL:automatic] xref: BTO:0000367 xref: CALOHA:TS-0213 xref: EMAPA:27235 xref: FMA:14942 xref: MA:0003207 xref: SCTID:362146003 is_a: UBERON:0001204 ! mucosa of small intestine intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0002114 ! duodenum relationship: part_of UBERON:0002114 ! duodenum property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0000323 name: late embryo namespace: uberon def: "An embryo that is at the late embryonic stage; this stage covers late steps of the embryogenesis with a fully formed embryo still developing before birth or egg hatching." [https://orcid.org/0000-0003-3308-6245] subset: efo_slim subset: pheno_slim synonym: "embryo late growth stage" RELATED [BTO:0000449] synonym: "embryo late stage" RELATED [BTO:0000449] synonym: "fetus" NARROW [BTO:0000449] xref: BTO:0000449 xref: CALOHA:TS-0360 xref: EFO:0001323 xref: FBbt:00005333 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:63919 xref: GAID:552 xref: MESH:D005333 xref: NCIT:C13235 xref: SCTID:83418008 xref: UMLS:C0015965 {source="ncithesaurus:Fetus"} is_a: UBERON:0000922 ! embryo intersection_of: UBERON:0000922 ! embryo intersection_of: existence_starts_and_ends_during UBERON:0007220 ! late embryonic stage relationship: existence_starts_and_ends_during UBERON:0007220 ! late embryonic stage property_value: editor_note "TODO - check fetus/embryo. WP: An embryo is a multicellular diploid eukaryote in its earliest stage of development, from the time of first cell division until birth, hatching, or germination. In humans, it is called an embryo until about eight weeks after fertilization (i.e. ten weeks LMP), and from then it is instead called a fetus." xsd:string property_value: UBPROP:0000001 "Fetal structure, which is a developmental form of a vertebrate animal at any given time point from 8 weeks of gestation to birth (or hatching). Examples: There is only one fetus[FMA:63919]." xsd:string {source="FMA:63919"} [Term] id: UBERON:0000325 name: gastric gland namespace: uberon def: "The branched tubular glands found in the mucosa of the fundus and body of the stomach which contain parietal cells that secrete hydrochloric acid and zymogenic cells that produce pepsin." [MGI:anna] subset: organ_slim subset: pheno_slim xref: BTO:0000503 xref: EMAPA:27181 xref: FMA:14919 is_a: UBERON:0002365 {source="cjm"} ! exocrine gland is_a: UBERON:0003294 ! gland of foregut relationship: part_of UBERON:0006924 {source="ISBN:0073040584"} ! stomach glandular epithelium [Term] id: UBERON:0000326 name: pancreatic juice namespace: uberon def: "Pancreatic juice is slightly alkaline and contains numerous enzymes and inactive enzyme precursors including alpha-amylase, chymotrypsinogen, lipase, procarboxypeptidase, proelastase, prophospholipase A2, ribonuclease, and trypsinogen. Its high concentration of bicarbonate ions helps to neutralize the acid from the stomach." [GO:0030157] synonym: "pancreatic fluid" RELATED [] synonym: "pancreatic secretion" RELATED [] synonym: "succus pancreaticus" RELATED [BTO:0000504] xref: BTO:0000504 xref: CALOHA:TS-2235 xref: FMA:62973 xref: GAID:1166 xref: MESH:D010189 is_a: UBERON:0000456 ! secretion of exocrine gland intersection_of: UBERON:0000456 ! secretion of exocrine gland intersection_of: produced_by UBERON:0001264 ! pancreas relationship: produced_by UBERON:0001264 ! pancreas [Term] id: UBERON:0000328 name: gut wall namespace: uberon def: "The wall of the digestive tract. This encompasses all parts of the digestive tract with the exception of the lumen (cavity)." [http://orcid.org/0000-0002-6601-2165] synonym: "digestive tract wall" EXACT [] synonym: "wall of alimentary tract" RELATED [] synonym: "wall of digestive tract" EXACT [] synonym: "wall of gut" EXACT [FMA:45653] xref: BTO:0000547 xref: FMA:45653 is_a: UBERON:0000060 ! anatomical wall intersection_of: UBERON:0000060 ! anatomical wall intersection_of: part_of UBERON:0001555 ! digestive tract relationship: part_of UBERON:0001555 ! digestive tract property_value: curator_notes "We model the digestive tract as consisting of two parts: the wall and the lumen." xsd:string [Term] id: UBERON:0000332 name: yellow bone marrow namespace: uberon def: "Bone marrow in which the fat cells predominate in the meshes of the reticular network." [http://medical-dictionary.thefreedictionary.com/Yellow+Marrow] synonym: "fat marrow" RELATED [BTO:0000635] synonym: "medulla ossium flava" EXACT OMO:0003011 [BTO:0000635] synonym: "yellow marrow" EXACT [BTO:0000635] xref: BTO:0000635 xref: FMA:74596 xref: SCTID:328639002 xref: SCTID:5023006 is_a: UBERON:0002371 ! bone marrow intersection_of: UBERON:0002371 ! bone marrow intersection_of: composed_primarily_of CL:0000136 ! adipocyte relationship: composed_primarily_of CL:0000136 ! adipocyte relationship: part_of UBERON:0007195 ! stroma of bone marrow [Term] id: UBERON:0000333 name: intestinal gland namespace: uberon def: "A gland that is part of the intestinal mucosa. Examples include the intestinal crypts, duodenal gland[cjm]." [https://orcid.org/0000-0002-6601-2165] subset: organ_slim synonym: "bowel mucosa gland" EXACT [OBOL:automatic] synonym: "bowel mucosa of organ gland" EXACT [OBOL:automatic] synonym: "bowel mucous membrane gland" EXACT [OBOL:automatic] synonym: "bowel organ mucosa gland" EXACT [OBOL:automatic] synonym: "gland of bowel mucosa" EXACT [OBOL:automatic] synonym: "gland of bowel mucosa of organ" EXACT [OBOL:automatic] synonym: "gland of bowel mucous membrane" EXACT [OBOL:automatic] synonym: "gland of bowel organ mucosa" EXACT [OBOL:automatic] synonym: "gland of intestinal mucosa" EXACT [OBOL:automatic] synonym: "gland of intestine mucosa" EXACT [OBOL:automatic] synonym: "gland of intestine mucosa of organ" EXACT [OBOL:automatic] synonym: "gland of intestine mucous membrane" EXACT [OBOL:automatic] synonym: "gland of intestine organ mucosa" EXACT [OBOL:automatic] synonym: "gland of mucosa of bowel" EXACT [OBOL:automatic] synonym: "gland of mucosa of intestine" EXACT [OBOL:automatic] synonym: "gland of mucosa of organ of bowel" EXACT [OBOL:automatic] synonym: "gland of mucosa of organ of intestine" EXACT [OBOL:automatic] synonym: "gland of mucous membrane of bowel" EXACT [OBOL:automatic] synonym: "gland of mucous membrane of intestine" EXACT [OBOL:automatic] synonym: "gland of organ mucosa of bowel" EXACT [OBOL:automatic] synonym: "gland of organ mucosa of intestine" EXACT [OBOL:automatic] synonym: "glandula intestinalis" EXACT [FMA:15052] synonym: "glandulae intestinales" RELATED [] synonym: "intestinal mucosa gland" EXACT [OBOL:automatic] synonym: "intestine mucosa gland" EXACT [OBOL:automatic] synonym: "intestine mucosa of organ gland" EXACT [OBOL:automatic] synonym: "intestine mucous membrane gland" EXACT [OBOL:automatic] synonym: "intestine organ mucosa gland" EXACT [OBOL:automatic] synonym: "mucosa of bowel gland" EXACT [OBOL:automatic] synonym: "mucosa of intestine gland" EXACT [OBOL:automatic] synonym: "mucosa of organ of bowel gland" EXACT [OBOL:automatic] synonym: "mucosa of organ of intestine gland" EXACT [OBOL:automatic] synonym: "mucous membrane of bowel gland" EXACT [OBOL:automatic] synonym: "mucous membrane of intestine gland" EXACT [OBOL:automatic] synonym: "organ mucosa of bowel gland" EXACT [OBOL:automatic] synonym: "organ mucosa of intestine gland" EXACT [OBOL:automatic] xref: BTO:0000640 xref: FMA:15052 xref: SCTID:266297002 is_a: UBERON:0003408 ! gland of digestive tract intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0001242 ! intestinal mucosa relationship: part_of UBERON:0001242 ! intestinal mucosa property_value: UBPROP:0000012 "Note that some sources treat 'intestinal gland' as synonymous with crypts" xsd:string [Term] id: UBERON:0000344 name: mucosa namespace: uberon def: "A lining of mostly endodermal origin, covered in epithelium, which is involved in absorption and secretion. They line various body cavities that are exposed to the external environment and internal organs. It is at several places continuous with skin: at the nostrils, the lips, the ears, the genital area, and the anus. The sticky, thick fluid secreted by the mucous membranes and gland is termed mucus. The term mucous membrane refers to where they are found in the body and not every mucous membrane secretes mucus[WP]." [Wikipedia:Mucous_membrane] subset: pheno_slim synonym: "mucosa of organ" EXACT [FMA:85355] synonym: "mucosa of organ part" EXACT [FMA:85358] synonym: "mucosal region" EXACT [FMA:85358] synonym: "mucous membrane" EXACT [FMA:85355] synonym: "organ mucosa" EXACT [FMA:85355] synonym: "region of mucosa" RELATED [FMA:85358] synonym: "tunica mucosa" RELATED OMO:0003011 [BTO:0000886, Wikipedia:Mucous_membrane] xref: AEO:0000199 xref: BTO:0000886 xref: CALOHA:TS-2031 xref: EHDAA2_RETIRED:0003234 xref: EV:0100382 xref: FMA:85355 xref: FMA:85358 xref: GAID:297 xref: galen:Mucosa xref: MESH:D009092 xref: NCIT:C13166 xref: SCTID:361693009 xref: UMLS:C0026724 {source="ncithesaurus:Mucosa"} xref: Wikipedia:Mucous_membrane is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0004923 ! organ component layer relationship: has_part UBERON:0000483 ! epithelium relationship: has_part UBERON:0002384 ! connective tissue relationship: only_in_taxon NCBITaxon:7711 ! Chordata property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/4/4e/Ens.png" xsd:anyURI property_value: depiction "http://upload.wikimedia.org/wikipedia/en/thumb/4/4e/Ens.png/200px-Ens.png" xsd:anyURI property_value: RO:0002171 UBERON:0000009 property_value: UBPROP:0000007 "mucosal" xsd:string property_value: UBPROP:0000012 "FMA has mucosa vs region of mucosa; these are subtypes of Mucosa: Mucosa of gallbladder, tongue, .... The following are subtypes of Region of mucosa: Mucosa of zone of stomach, trachea, bronchus, dorsum of tongue.... Depends on whether the covered area is an organ or organ component. Uberon does not regard organ vs organ component as crucial distinction and thus collapses these into a single class deliberately" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0000353 name: parenchyma namespace: uberon def: "Functional part of an organ in the body. This is in contrast to the stroma, which refers to the structural tissue of organs, being exactly, connective tissues." [Wikipedia:Parenchyma] xref: BTO:0000999 {sssom:mapping_justification="vocab:ManualMappingCuration", sssom:author_id="https://orcid.org/0000-0003-4423-4370", sssom:mapping_provider="https://github.com/biopragmatics/biomappings"} xref: BTO:0001539 {sssom:mapping_justification="vocab:ManualMappingCuration", sssom:author_id="https://orcid.org/0000-0003-4423-4370", sssom:mapping_provider="https://github.com/biopragmatics/biomappings"} xref: EHDAA:3015 xref: EHDAA:3905 xref: EHDAA:3999 xref: EHDAA:4005 xref: EHDAA:6899 xref: EHDAA:6903 xref: EHDAA:6994 xref: EHDAA:8086 xref: EHDAA:9182 xref: EHDAA:9190 xref: EHDAA:9196 xref: EHDAA:9202 xref: FMA:45732 xref: NCIT:C74601 xref: UMLS:C0933845 {source="ncithesaurus:Parenchyma"} xref: Wikipedia:Parenchyma is_a: UBERON:0000064 ! organ part disjoint_from: UBERON:0003891 ! stroma relationship: capable_of GO:0032501 ! multicellular organismal process relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa property_value: UBPROP:0000007 "parenchymal" xsd:string property_value: UBPROP:0000011 "Early in development the mammalian embryo has three distinct layers: ectoderm (external layer), endoderm (internal layer) and in between those two layers the middle layer or mesoderm. The parenchyma of most organs is of ectodermal (brain, skin) or endodermal origin (lungs, gastrointestinal tract, liver, pancreas). The parenchyma of a few organs (spleen, kidneys, heart) is of mesodermal origin. The stroma of all organs is of mesodermal origin" xsd:string {source="WP"} property_value: UBPROP:0000012 "the FMA definition is more restrictive, and limits this to solid organs. This would seem to cause problems for the lung parenchyma, except FMA classifies Lung as solid rather than cavitated" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0000355 name: pharyngeal mucosa namespace: uberon alt_id: UBERON:0003344 def: "A mucosa that is part of a pharynx [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of organ of pharynx" EXACT [OBOL:automatic] synonym: "mucosa of pharynx" EXACT [OBOL:automatic] synonym: "mucous membrane of pharynx" EXACT [FMA:55031, OBOL:automatic] synonym: "mucous membrane of the pharynx" RELATED [BTO:0001047] synonym: "organ mucosa of pharynx" EXACT [OBOL:automatic] synonym: "pharynx mucosa" EXACT [OBOL:automatic] synonym: "pharynx mucosa of organ" EXACT [OBOL:automatic] synonym: "pharynx mucous membrane" EXACT [OBOL:automatic] synonym: "pharynx organ mucosa" EXACT [OBOL:automatic] synonym: "tunica mucosa pharyngea" EXACT OMO:0003011 [FMA:55031, FMA:TA] synonym: "tunica mucosa pharyngis" EXACT [] xref: BTO:0001047 xref: EMAPA:26957 xref: FMA:55031 xref: MA:0003143 xref: SCTID:362121003 is_a: UBERON:0004785 ! respiratory system mucosa intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001042 ! chordate pharynx relationship: part_of UBERON:0001042 ! chordate pharynx [Term] id: UBERON:0000358 name: blastocyst namespace: uberon def: "The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm[GO]." [GO:0001824, Wikipedia:Blastocyst] subset: efo_slim synonym: "blastocystis" RELATED OMO:0003011 [Wikipedia:Blastocyst] synonym: "blastula" RELATED [FMA:83041] xref: BTO:0001099 xref: CALOHA:TS-0076 xref: EFO:0000295 xref: EMAPA:36035 xref: EV:0100394 xref: FMA:83041 xref: GAID:1153 xref: MESH:D001755 xref: NCIT:C13739 xref: SCTID:308837009 xref: UMLS:C1281743 {source="ncithesaurus:Blastocyst"} xref: Wikipedia:Blastocyst is_a: UBERON:0002050 ! embryonic structure relationship: develops_from UBERON:0000085 ! morula relationship: existence_starts_and_ends_during UBERON:0000108 ! blastula stage relationship: has_part UBERON:0000087 ! inner cell mass relationship: has_part UBERON:0000088 ! trophoblast relationship: only_in_taxon NCBITaxon:32525 ! Theria relationship: part_of UBERON:0000307 ! blastula property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/7/72/Blastocyst_English.svg" xsd:anyURI property_value: editor_note "Gilbert fig11.32 has blastocyst has giving rise to ICM and trophoblast (which in this source is a synonym for trophectoderm)" xsd:string [Term] id: UBERON:0000361 name: red bone marrow namespace: uberon def: "The red vascular substance consisting of connective tissue and blood vessels, containing primitive blood cells, macrophages, megakaryocytes, and fat cells. Red marrow is found in the cavities of many bones. It manufactures and releases leukocytes and erythrocytes into the bloodstream." [http://medical-dictionary.thefreedictionary.com/red+marrow] synonym: "medulla ossium rubra" EXACT OMO:0003011 [BTO:0001160] synonym: "parenchyma of none marrow marrow" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "parenchymal red marrow" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "red marrow" EXACT [BTO:0001160] xref: BTO:0001160 xref: FMA:74595 xref: SCTID:328538003 xref: SCTID:75330005 is_a: UBERON:0002371 ! bone marrow intersection_of: UBERON:0002371 ! bone marrow intersection_of: composed_primarily_of CL:0000988 ! hematopoietic cell relationship: composed_primarily_of CL:0000988 ! hematopoietic cell relationship: part_of UBERON:0012429 ! hematopoietic tissue [Term] id: UBERON:0000371 name: syncytiotrophoblast namespace: uberon def: "Extraembryonic cells of trophoblastic shell surrounding embryo, outside the cytotrophoblast layer, involved with implantation of the blastocyst by eroding extracellular matrix surrounding maternal endometrial cells at site of implantation, also contribute to villi. (dark staining, multinucleated)." [http://embryology.med.unsw.edu.au/Notes/placenta5.htm, Wikipedia:Syncytiotrophoblast] synonym: "syncitiotrophoblast" RELATED [] synonym: "syncitiotrophoblastus" RELATED OMO:0003011 [Wikipedia:Syncytiotrophoblast] synonym: "syncytial trophoblast" EXACT [FMA:83040] synonym: "syntrophoblast" RELATED [] synonym: "syntrophoblast layer" EXACT [ISBN:0073040584] xref: BTO:0001335 xref: EHDAA:129 xref: EHDAA:91 xref: EMAPA:16068 xref: FMA:83040 xref: NCIT:C33918 xref: SCTID:256965005 xref: UMLS:C1135936 {source="ncithesaurus:Syncytiotrophoblast"} xref: Wikipedia:Syncytiotrophoblast is_a: UBERON:0002050 {source="FMA"} ! embryonic structure relationship: composed_primarily_of CL:0000525 ! syncytiotrophoblast cell relationship: part_of UBERON:0004364 {source="EMAPA"} ! ectoplacental cone property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/d/df/Gray36.png" xsd:anyURI [Term] id: UBERON:0000377 name: maxillary nerve namespace: uberon def: "The sensory nerve subdivision of the trigeminal nerve that transmits sensory information from the palate, upper teeth and gingiva, the skin between the palpebral fissure and the mouth, and from the nasal cavity and maxillary sinuses." [MP:0009799, Wikipedia:Maxillary_nerve] subset: human_reference_atlas subset: pheno_slim synonym: "maxillary division [V2]" EXACT [FMA:52724] synonym: "maxillary division [Vb]" EXACT [FMA:52724] synonym: "maxillary division of fifth cranial nerve" EXACT [FMA:52724] synonym: "maxillary division of trigeminal nerve (Vb; V2)" EXACT [FMA:52724] synonym: "maxillary nerve [V2]" EXACT [FMA:52724] synonym: "maxillary nerve [Vb]" EXACT [FMA:52724] synonym: "n. maxillaris" RELATED OMO:0003011 [Wikipedia:Maxillary_nerve] synonym: "nervus maxillaris" RELATED [BTO:0001378] synonym: "nervus maxillaris (Vb; V2)" EXACT [FMA:52724] synonym: "nervus maxillaris [v2]" EXACT OMO:0003011 [FMA:52724, FMA:TA] synonym: "nervus maxillaris [vb]" EXACT OMO:0003011 [FMA:52724, FMA:TA] synonym: "ramus maxillaris (ramus V2)" EXACT [AAO:0010670] synonym: "second division of fifth cranial nerve" EXACT [FMA:52724] synonym: "second division of trigeminal nerve" EXACT [FMA:52724] synonym: "trigeminal nerve maxillary division" RELATED [EMAPA:17799] synonym: "trigeminal V nerve maxillary division" EXACT [MA:0001103] xref: AAO:0010670 xref: BTO:0001378 xref: EHDAA2:0002087 xref: EMAPA:17799 xref: FMA:52724 xref: GAID:836 xref: MA:0001103 xref: MESH:D008442 xref: SCTID:280211001 xref: VHOG:0001346 xref: Wikipedia:Maxillary_nerve is_a: UBERON:0011779 ! nerve of head region relationship: branching_part_of UBERON:0001645 ! trigeminal nerve relationship: part_of UBERON:0001645 ! trigeminal nerve property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/a/a9/Gray779.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Medial ramus (sensory) of the trigeminal nerve.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010670", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000002 "relationship loss: part_of trunk maxillary-mandibularis (AAO:0010669)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010670", ontology="AAO"} [Term] id: UBERON:0000379 name: tracheal mucosa namespace: uberon def: "A mucosa that is part of a respiratory airway." [OBOL:automatic] synonym: "mucosa of organ of trachea" EXACT [OBOL:automatic] synonym: "mucosa of organ of windpipe" EXACT [OBOL:automatic] synonym: "mucosa of trachea" EXACT [OBOL:automatic] synonym: "mucosa of windpipe" EXACT [OBOL:automatic] synonym: "mucous membrane of trachea" EXACT [FMA:7471, OBOL:automatic] synonym: "mucous membrane of windpipe" EXACT [OBOL:automatic] synonym: "organ mucosa of trachea" EXACT [OBOL:automatic] synonym: "organ mucosa of windpipe" EXACT [OBOL:automatic] synonym: "trachea mucosa" EXACT [OBOL:automatic] synonym: "trachea mucosa of organ" EXACT [OBOL:automatic] synonym: "trachea mucous membrane" EXACT [OBOL:automatic] synonym: "trachea organ mucosa" EXACT [OBOL:automatic] synonym: "tracheal mucous membrane" EXACT [FMA:7471] synonym: "tunica mucosa (tracheae)" EXACT [FMA:7471] synonym: "tunica mucosa tracheae" EXACT OMO:0003011 [FMA:7471, FMA:TA] synonym: "windpipe mucosa" EXACT [OBOL:automatic] synonym: "windpipe mucosa of organ" EXACT [OBOL:automatic] synonym: "windpipe mucous membrane" EXACT [OBOL:automatic] synonym: "windpipe organ mucosa" EXACT [OBOL:automatic] xref: BTO:0001390 xref: FMA:7471 xref: SCTID:660006 is_a: UBERON:0004785 ! respiratory system mucosa intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001005 ! respiratory airway relationship: part_of UBERON:0001005 ! respiratory airway [Term] id: UBERON:0000383 name: musculature of body namespace: uberon def: "The subdivision of the musculoskeletal system that consists of all the muscles of the body[VSAO, modified]." [VSAO:0000033] subset: efo_slim subset: human_reference_atlas subset: pheno_slim synonym: "muscle system" EXACT [] synonym: "muscle system of body" EXACT [] synonym: "muscular system" EXACT [FMA:72954] synonym: "musculature system" EXACT [BILA:0000088] synonym: "muskelsystem" RELATED [BTO:0001485] synonym: "set of all muscles" EXACT [FMA:72954] synonym: "set of muscles of body" EXACT [FMA:72954] synonym: "vertebrate muscular system" EXACT [BTO:0001369] xref: AAO:0000307 xref: BILA:0000088 xref: BTO:0001369 xref: BTO:0001485 xref: EFO:0000801 xref: EMAPA:35578 xref: FMA:72954 xref: MA:0002888 xref: MAT:0000025 xref: MIAA:0000025 xref: VSAO:0000033 xref: XAO:0004042 is_a: UBERON:0011216 ! organ system subdivision intersection_of: UBERON:0011216 ! organ system subdivision intersection_of: composed_primarily_of UBERON:0001015 ! musculature relationship: capable_of GO:0003012 ! muscle system process relationship: composed_primarily_of UBERON:0001015 ! musculature relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa property_value: editor_note "consider whether this should be restricted to skeletal musculature. See https://github.com/obophenotype/uberon/issues/77" xsd:string property_value: RO:0002161 NCBITaxon:6040 property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Anatomical system that consists of the muscles of the body.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000033", ontology="VSAO", source="VSAO:curator"} property_value: UBPROP:0000012 "we place the MA term musculature here, rather than under uberon:musculature, as this seems more appropriate given the structure of MA" xsd:string {external_ontology="MA"} [Term] id: UBERON:0000389 name: lens cortex namespace: uberon def: "Tissue that surrounds the lens nucleus." [http://www.thefreedictionary.com/lens+cortex] subset: human_reference_atlas synonym: "cortex of lens" EXACT [FMA:58970] xref: BTO:0001632 xref: CALOHA:TS-0542 xref: FMA:58970 xref: MESH:D007904 xref: SCTID:280626006 is_a: UBERON:0000479 ! tissue is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0000479 ! tissue intersection_of: surrounds UBERON:0000390 ! lens nucleus relationship: develops_from UBERON:0005614 ! lens anterior epithelium relationship: part_of UBERON:0000965 ! lens of camera-type eye relationship: surrounds UBERON:0000390 ! lens nucleus property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0000390 name: lens nucleus namespace: uberon def: "The core of the crystalline lens, surrounded by the cortex." [BTO:0001633] subset: human_reference_atlas synonym: "nucleus of lens" EXACT [FMA:58971] xref: BTO:0001633 xref: FMA:58971 xref: MESH:D007907 xref: SCTID:280628007 is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0034944 ! zone of organ intersection_of: UBERON:0034944 ! zone of organ intersection_of: surrounded_by UBERON:0000389 ! lens cortex relationship: develops_from UBERON:0005614 ! lens anterior epithelium relationship: part_of UBERON:0000965 ! lens of camera-type eye relationship: surrounded_by UBERON:0000389 ! lens cortex property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0000397 name: colonic epithelium namespace: uberon def: "An epithelium that is part of a colon [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas subset: vertebrate_core synonym: "colon epithelial tissue" EXACT [OBOL:automatic] synonym: "colon epithelium" EXACT [FMA:17302, OBOL:automatic] synonym: "epithelial tissue of colon" EXACT [OBOL:automatic] synonym: "epithelial tissue of large bowel" EXACT [OBOL:automatic] synonym: "epithelium of colon" EXACT [OBOL:automatic] synonym: "epithelium of large bowel" EXACT [OBOL:automatic] synonym: "large bowel epithelial tissue" EXACT [OBOL:automatic] synonym: "large bowel epithelium" EXACT [OBOL:automatic] synonym: "posterior intestine epithelium" EXACT [ZFA:0005128] xref: BTO:0001709 xref: CALOHA:TS-0163 xref: EMAPA:18941 xref: FMA:17302 xref: MA:0003195 xref: SCTID:42978003 xref: TAO:0005128 xref: ZFA:0005128 is_a: UBERON:0001278 ! epithelium of large intestine intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001155 ! colon relationship: part_of UBERON:0001155 ! colon property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Intestinal epithelium which lines the lumen of the posterior intestine.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005128", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0000409 name: serous gland namespace: uberon def: "A gland in which the principal secretory cells are serous secreting cells." [http://orcid.org/0000-0002-6601-2165, http://www.siumed.edu/~dking2/intro/glands.htm] subset: organ_slim subset: pheno_slim xref: BTO:0001837 xref: EMAPA:37950 {source="MA:th"} xref: FMA:62889 xref: Wikipedia:Serous_gland is_a: UBERON:0002365 ! exocrine gland intersection_of: UBERON:0002365 ! exocrine gland intersection_of: has_part CL:0000313 ! serous secreting cell relationship: has_part CL:0000313 ! serous secreting cell relationship: has_part UBERON:0013232 ! serous acinus relationship: produces UBERON:0007794 ! secretion of serous gland property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/c/c0/Gray1021.png" xsd:anyURI property_value: UBPROP:0000001 "glands that secrete watery albuminous material that often contains enzymes[MP:0008052]." xsd:string {source="MP:0008052"} [Term] id: UBERON:0000414 name: mucous gland namespace: uberon def: "A gland in which the principal secretory cells are mucus secreting cells." [http://orcid.org/0000-0002-6601-2165, http://www.siumed.edu/~dking2/intro/glands.htm] subset: organ_slim synonym: "glandula mucosa" EXACT OMO:0003011 [Wikipedia:Mucous_gland] synonym: "muciparous gland" RELATED [BTO:0001979] synonym: "mucous secreting gland" RELATED [] synonym: "mucus gland" RELATED [] synonym: "mucus-secreting gland" RELATED [] xref: AAO:0010601 xref: BTO:0001979 xref: EMAPA:37913 {source="MA:th"} xref: FMA:62888 xref: Wikipedia:Mucous_gland is_a: UBERON:0002365 ! exocrine gland intersection_of: UBERON:0002365 ! exocrine gland intersection_of: has_part CL:0000319 ! mucus secreting cell relationship: capable_of GO:0070254 ! mucus secretion relationship: has_part CL:0000319 ! mucus secreting cell relationship: produces UBERON:0000912 ! mucus property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/c/c0/Gray1021.png" xsd:anyURI property_value: UBPROP:0000008 "In frogs and salamanders, this is the smaller of the two types of gland, the other being the granular (poison) gland. In these species the mucous gland is a cluster of cells that release secretion into a common duct[Kardong]" xsd:string {scope="NCBITaxon:8292", source="ISBN:0073040584"} [Term] id: UBERON:0000415 name: artery wall namespace: uberon def: "An anatomical wall that is part of an artery [Automatically generated definition]." [OBOL:automatic] synonym: "arterial wall" EXACT [FMA:14155] synonym: "wall of artery" EXACT [FMA:14155] xref: BTO:0002009 xref: FMA:14155 xref: galen:ArterialWall is_a: UBERON:0035965 ! wall of blood vessel intersection_of: UBERON:0000060 ! anatomical wall intersection_of: part_of UBERON:0001637 ! artery relationship: part_of UBERON:0001637 ! artery [Term] id: UBERON:0000440 name: trabecula namespace: uberon def: "A small, often microscopic, tissue element in the form of a small beam, strut or rod, generally having a mechanical function, and usually but not necessarily composed of dense collagenous tissue. On histological section, a trabecula can look like a septum, but in three dimensions they are topologically distinct, with trabeculae being roughly rod or pillar-shaped and septa being sheet-like. Trabeculae are usually composed of dense fibrous tissue, i.e. mainly of collagen, and in most cases provide mechanical strengthening or stiffening to a soft solid organ, such as the spleen. They can be composed of other materials, such as bone or muscle[WP]." [GO:0060343, Wikipedia:Trabecula] subset: grouping_class subset: pheno_slim synonym: "trabeculae" EXACT OMO:0003004 [] xref: BTO:0002501 xref: FMA:85273 xref: Wikipedia:Trabecula is_a: UBERON:0000064 ! organ part relationship: has_part UBERON:0002384 ! connective tissue relationship: has_quality PATO:0001873 ! cylindrical property_value: UBPROP:0000007 "trabecular" xsd:string [Term] id: UBERON:0000442 name: right testicular vein namespace: uberon def: "A vein that drains the left pampiniform plexus and empties into the left renal vein." [Dorlands_Medical_Dictionary:MerckSource] subset: human_reference_atlas synonym: "right spermatic vein" EXACT [MA:0002220] synonym: "vena testicularis (adrenalis) dextra" EXACT [FMA:14341] synonym: "vena testicularis dextra" RELATED [BTO:0002679] synonym: "vena testicularis sinistra" RELATED [BTO:0002680] xref: BTO:0002679 xref: EMAPA:37383 {source="MA:th"} xref: FMA:14341 xref: MA:0002220 xref: NCIT:C52697 xref: SCTID:53500001 is_a: UBERON:0001144 ! testicular vein intersection_of: UBERON:0001144 ! testicular vein intersection_of: drains UBERON:0004534 ! right testis relationship: connected_to UBERON:0001142 ! left renal vein relationship: drains UBERON:0004534 ! right testis relationship: in_left_side_of UBERON:0000468 ! multicellular organism property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0000443 name: left testicular vein namespace: uberon def: "A vein that drains the right pampiniform plexus and empties into the inferior vena cava." [Dorlands_Medical_Dictionary:MerckSource] subset: human_reference_atlas synonym: "left spermatic vein" EXACT [MA:0002219] synonym: "vena testicularis dextra" RELATED [BTO:0002679] synonym: "vena testicularis sinistra" RELATED [BTO:0002680] xref: BTO:0002680 xref: EMAPA:37167 {source="MA:th"} xref: FMA:14345 xref: MA:0002219 xref: NCIT:C52696 xref: SCTID:90988008 is_a: UBERON:0001144 ! testicular vein intersection_of: UBERON:0001144 ! testicular vein intersection_of: drains UBERON:0004533 ! left testis relationship: connected_to UBERON:0001142 ! left renal vein relationship: drains UBERON:0004533 ! left testis relationship: in_left_side_of UBERON:0000468 ! multicellular organism property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0000456 name: secretion of exocrine gland namespace: uberon alt_id: UBERON:0006540 def: "A portion of organism substance that is produced by exocrine glands." [http://orcid.org/0000-0002-6601-2165] synonym: "bodily secretion" EXACT [MESH:D012634] synonym: "exocrine gland fluid" RELATED [] synonym: "exocrine gland fluid or secretion" RELATED [] synonym: "exocrine gland fluid/secretion" EXACT [MA:0002504] synonym: "exocrine gland secretion" RELATED [] synonym: "external secretion" RELATED [BTO:0002977] synonym: "secreted substance" EXACT [] synonym: "secretion" BROAD [FMA:9675] xref: AEO:0001005 xref: BTO:0002977 xref: BTO:0002979 xref: EMAPA:36535 xref: FMA:9675 xref: galen:Secretion xref: MA:0002504 xref: MESH:D012634 xref: NCIT:C34062 xref: UMLS:C1516992 {source="ncithesaurus:Exocrine_Gland_Fluid_or_Secretion"} is_a: UBERON:0000463 ! organism substance intersection_of: UBERON:0000463 ! organism substance intersection_of: produced_by UBERON:0002365 ! exocrine gland relationship: produced_by UBERON:0002365 ! exocrine gland property_value: UBPROP:0000012 "BTO has two distunct classes, with exocrine glandular secretion a subtype of secretion - however, all examples in BTO directly under secretion appear to be exocrine gland secretions" xsd:string {external_ontology="BTO"} [Term] id: UBERON:0000459 name: uterine wall namespace: uberon def: "An anatomical wall that is part of a uterus [Automatically generated definition]." [OBOL:automatic] synonym: "anatomical wall of uterus" EXACT [OBOL:automatic] synonym: "uterus anatomical wall" EXACT [OBOL:automatic] synonym: "uterus wall" EXACT [OBOL:automatic] synonym: "wall of uterus" EXACT [OBOL:automatic] xref: BTO:0003083 xref: FMA:17560 xref: SCTID:245485002 is_a: UBERON:0000060 ! anatomical wall is_a: UBERON:0005156 ! reproductive structure intersection_of: UBERON:0000060 ! anatomical wall intersection_of: part_of UBERON:0000995 ! uterus relationship: part_of UBERON:0000995 ! uterus [Term] id: UBERON:0000463 name: organism substance namespace: uberon def: "Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body." [http://orcid.org/0000-0001-9114-8737] subset: common_anatomy subset: pheno_slim subset: upper_level synonym: "body fluid or substance" EXACT [MA:0002450] synonym: "body substance" EXACT [FMA:9669] synonym: "organism substance" EXACT [CARO:0000004] synonym: "portion of body substance" EXACT [FMA:9669] synonym: "portion of organism substance" EXACT [ZFA:0001487] xref: AAO:0010839 xref: AEO:0000004 xref: BILA:0000004 xref: CALOHA:TS-2101 xref: CARO:0000004 xref: EHDAA2:0003004 xref: EMAPA:35178 xref: FBbt:00007019 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:9669 xref: galen:BodySubstance xref: HAO:0000004 xref: MA:0002450 xref: NCIT:C13236 xref: SPD:0000008 xref: TAO:0001487 xref: TGMA:0001824 xref: VHOG:0001726 xref: XAO:0004001 xref: ZFA:0001487 is_a: UBERON:0000465 ! material anatomical entity relationship: has_quality PATO:0002198 ! quality of a substance relationship: part_of UBERON:0000468 {notes="this relationship may be too strong and may be weakened in future"} ! multicellular organism property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0000464 name: anatomical space namespace: uberon def: "Non-material anatomical entity of three dimensions, that is generated by morphogenetic or other physiologic processes; is surrounded by one or more anatomical structures; contains one or more organism substances or anatomical structures." [http://orcid.org/0000-0001-9114-8737] subset: common_anatomy subset: upper_level synonym: "anatomical spaces" RELATED OMO:0003004 [ZFA:0001643] synonym: "lumen" BROAD [] synonym: "lumen space" EXACT [] synonym: "space" BROAD [] xref: AAO:0010110 xref: AEO:0000005 xref: BILA:0000005 xref: CARO:0000005 xref: EHDAA2:0003005 xref: FBbt:00007017 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:5897 xref: HAO:0000005 xref: NCIT:C94478 xref: TAO:0001668 xref: TGMA:0001825 xref: UMLS:C0524461 {source="ncithesaurus:Lumen_Space"} xref: VHOG:0001728 xref: XAO:0003190 xref: ZFA:0001643 is_a: UBERON:0000466 ! immaterial anatomical entity relationship: surrounded_by UBERON:0000061 ! anatomical structure property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0000465 name: material anatomical entity namespace: uberon def: "Anatomical entity that has mass." [http://orcid.org/0000-0001-9114-8737] subset: common_anatomy subset: human_subset subset: mouse_subset subset: upper_level xref: AAO:0010264 xref: AEO:0000006 xref: BILA:0000006 xref: CARO:0000006 xref: EHDAA2:0003006 xref: FBbt:00007016 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:67165 xref: HAO:0000006 xref: TAO:0001836 xref: TGMA:0001826 xref: VHOG:0001721 is_a: BFO:0000040 ! material entity is_a: UBERON:0001062 ! anatomical entity disjoint_from: UBERON:0000466 ! immaterial anatomical entity property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0000466 name: immaterial anatomical entity namespace: uberon def: "Anatomical entity that has no mass." [http://orcid.org/0000-0001-9114-8737] subset: common_anatomy subset: upper_level synonym: "immaterial physical anatomical entity" EXACT [FMA:67112] xref: AAO:0010265 xref: AEO:0000007 xref: BILA:0000007 xref: CARO:0000007 xref: EHDAA2:0003007 xref: FBbt:00007015 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:67112 xref: HAO:0000007 xref: TAO:0001835 xref: TGMA:0001827 xref: VHOG:0001727 is_a: BFO:0000141 ! immaterial entity is_a: UBERON:0001062 ! anatomical entity property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0000467 name: anatomical system namespace: uberon def: "Multicellular, connected anatomical structure that has multiple organs as parts and whose parts work together to achieve some shared function." [CARO:0000011] subset: common_anatomy subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: upper_level synonym: "anatomical systems" RELATED OMO:0003004 [ZFA:0001439] synonym: "body system" EXACT [BIRNLEX:14] synonym: "connected anatomical system" EXACT [CARO:0000011] synonym: "organ system" EXACT [] synonym: "system" BROAD [GO:0048731] xref: AAO:0000007 xref: AEO:0000011 xref: BILA:0000011 xref: BIRNLEX:14 xref: BSA:0000049 xref: CALOHA:TS-2088 xref: CARO:0000011 xref: EHDAA2:0003011 xref: EHDAA:392 xref: EMAPA:16103 xref: EV:0100000 xref: FBbt:00004856 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:7149 xref: galen:AnatomicalSystem xref: HAO:0000011 xref: IDOMAL:0002460 {sssom:mapping_justification="vocab:ManualMappingCuration", sssom:author_id="https://orcid.org/0000-0003-4423-4370", sssom:mapping_provider="https://github.com/biopragmatics/biomappings"} xref: MA:0000003 xref: NCIT:C12919 xref: SCTID:278195005 xref: TAO:0001439 xref: TGMA:0001831 xref: UMLS:C0460002 {source="ncithesaurus:Organ_System"} xref: VHOG:0001725 xref: WBbt:0005746 xref: WBbt:0005763 xref: Wikipedia:Organ_system xref: XAO:0003002 xref: ZFA:0001439 is_a: UBERON:0000061 ! anatomical structure relationship: existence_starts_during_or_after UBERON:0000111 {gci_filler="NCBITaxon:6072", gci_relation="in_taxon"} ! organogenesis stage relationship: has_part UBERON:0000062 ! organ relationship: part_of UBERON:0000468 ! multicellular organism relationship: seeAlso EHDAA2:0001330 property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0000468 name: multicellular organism namespace: uberon def: "Anatomical structure that is an individual member of a species and consists of more than one cell." [CARO:0000012, http://orcid.org/0000-0001-9114-8737, Wikipedia:Multi-cellular_organism] subset: common_anatomy subset: efo_slim subset: pheno_slim subset: uberon_slim subset: upper_level synonym: "body" RELATED [AEO:0000103, BIRNLEX:18, FMA:256135, NCIT:C13041] synonym: "Koerper" RELATED [BTO:0001489] synonym: "multi-cellular organism" EXACT [CARO:0000012] synonym: "organism" BROAD [FBbt:00000001, VHOG:0000671, WBbt:0007833] synonym: "whole body" RELATED [BTO:0001489] synonym: "whole organism" RELATED [FBbt:00000001] xref: AAO:0010026 xref: AEO:0000191 xref: BILA:0000012 xref: BIRNLEX:18 xref: BSA:0000038 xref: BTO:0000042 xref: CARO:0000012 xref: EFO:0002906 xref: EHDAA2:0003103 xref: EHDAA2:0003191 xref: EHDAA:1 xref: EMAPA:25765 xref: EV:0100016 xref: FBbt:00000001 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:256135 xref: galen:Organism xref: HAO:0000012 xref: NCIT:C13041 xref: ncithesaurus:Whole_Organism xref: SCTID:243928005 xref: TADS:0000001 xref: TAO:0001094 xref: TGMA:0001832 xref: VHOG:0000671 xref: WBbt:0007833 xref: Wikipedia:Multi-cellular_organism xref: XAO:0003004 xref: ZFA:0001094 is_a: UBERON:0010000 ! multicellular anatomical structure property_value: editor_note "TODO - split body and mc organism? body continues after death stage" xsd:string property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 property_value: UBPROP:0000007 "organismal" xsd:string [Term] id: UBERON:0000471 name: compound organ component namespace: uberon def: "Multi-tissue structure that is part of a compound organ." [CARO:0000019, http://orcid.org/0000-0001-9114-8737] subset: upper_level synonym: "compound organ components" RELATED OMO:0003004 [ZFA:0001489] xref: AAO:0010017 xref: AEO:0000019 xref: BILA:0000019 xref: CARO:0000019 xref: EHDAA2:0003019 xref: HAO:0000019 xref: TAO:0001489 xref: TGMA:0001835 xref: XAO:0003039 xref: ZFA:0001489 is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0003103 ! compound organ property_value: curator_notes "this class was introduced for consistency with CARO, however, it has yet to be used in this or other ontologies. It may be retired in the future" xsd:string [Term] id: UBERON:0000473 name: testis namespace: uberon alt_id: UBERON:0002117 def: "A gonad of a male animal. A gonad produces and releases sperm." [http://orcid.org/0000-0002-6601-2165] subset: efo_slim subset: organ_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "gonad of male genitalia" EXACT [OBOL:automatic] synonym: "gonad of male reproductive system" EXACT [OBOL:automatic] synonym: "male gonad" EXACT [OBOL:automatic] synonym: "orchis" RELATED [BTO:0001363] synonym: "testes" RELATED OMO:0003004 [] synonym: "testicle" EXACT [FMA:7210] synonym: "testiculus" RELATED OMO:0003011 [BTO:0001363] xref: AAO:0000606 xref: BILA:0000124 xref: BSA:0000085 xref: BTO:0001363 xref: CALOHA:TS-1030 xref: EFO:0000984 xref: EHDAA2:0002007 xref: EHDAA:8146 xref: EMAPA:17972 xref: EV:0100102 xref: FBbt:00004928 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:7210 xref: GAID:396 xref: galen:Testis xref: HAO:0001007 xref: MA:0000411 xref: MAT:0000132 xref: MESH:D013737 xref: MIAA:0000132 xref: NCIT:C12412 xref: SCTID:181431007 xref: TAO:0000598 xref: UMLS:C0039597 {source="ncithesaurus:Testis"} xref: VHOG:0000252 xref: WBbt:0006794 xref: Wikipedia:Testis xref: XAO:0000157 xref: ZFA:0000598 is_a: UBERON:0000991 ! gonad is_a: UBERON:0003135 ! male reproductive organ intersection_of: UBERON:0000991 ! gonad intersection_of: part_of UBERON:0000079 ! male reproductive system disjoint_from: UBERON:0000992 ! ovary disjoint_from: UBERON:0009117 ! indifferent gonad relationship: develops_from UBERON:0009117 ! indifferent gonad relationship: in_lateral_side_of UBERON:0000468 {gci_relation="part_of", gci_filler="NCBITaxon:7742", notes="vertebrates"} ! multicellular organism property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/c/c3/Gray1144.png" xsd:anyURI property_value: UBPROP:0000001 "Male reproductive organ.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000598", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "(...) while it is likely that Urbilateria lacked a complex somatic reproductive system, it is at present impossible to speculate on whether or not it possessed a true gonad, let alone any other somatic adaptations for reproduction (reference 1); Examination of different vertebrate species shows that the adult gonad is remarkably similar in its morphology across different phylogenetic classes. Surprisingly, however, the cellular and molecular programs employed to create similar organs are not evolutionarily conserved (reference 2).[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000252", ontology="VHOG", source="DOI:10.1093/icb/icm052 Extavour CGM, Gray anatomy: phylogenetic patterns of somatic gonad structures and reproductive strategies across the Bilateria. Integrative and Comparative Biology (2007), DOI:10.1146/annurev.cellbio.042308.13350 DeFalco T and Capel B, Gonad morphogenesis in vertebrates: divergent means to a convergent end. Annual review of cell and developmental biology (2009)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "testicular" xsd:string property_value: UBPROP:0000008 "The testes are descended in metatherian and eutherian mammals, first transabdominally, then inguinoscrotally" xsd:string {source="ISBN:0123971756", taxon="NCBITaxon:40674"} [Term] id: UBERON:0000474 name: female reproductive system namespace: uberon def: "The organs and associated structures associated with bearing offspring in a female animal." [http://orcid.org/0000-0002-6601-2165, MP:0001119, Wikipedia:Female_genitalia] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "female genital system" RELATED [] synonym: "female genital tract" RELATED [] synonym: "female genitalia" RELATED [] synonym: "female genitals" RELATED OMO:0003004 [XAO:0000156] synonym: "female organism genitalia" EXACT [OBOL:automatic] synonym: "female organism reproductive system" EXACT [OBOL:automatic] synonym: "female reproductive tract" RELATED [MA:0000381] synonym: "genitalia of female organism" EXACT [OBOL:automatic] synonym: "gynaecological tissue" RELATED [BTO:0000083] synonym: "reproductive system of female organism" EXACT [OBOL:automatic] synonym: "systema genitale femininum" RELATED [BTO:0000083] xref: BTO:0000083 xref: CALOHA:TS-1303 xref: EFO:0000969 xref: EHDAA2:0000506 xref: EHDAA:8116 xref: EMAPA:17959 xref: EV:0100110 xref: FBbt:00004864 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:45663 xref: GAID:364 xref: HAO:0000324 xref: MA:0000381 xref: MESH:D005836 xref: MIAA:0000028 xref: NCIT:C12402 xref: SCTID:361386004 xref: TGMA:0000635 xref: UMLS:C0700038 {source="ncithesaurus:Female_Reproductive_System"} xref: VHOG:0000726 xref: Wikipedia:Female_genitalia xref: WikipediaCategory:Female_reproductive_system xref: XAO:0000156 is_a: UBERON:0000990 ! reproductive system intersection_of: UBERON:0000990 ! reproductive system intersection_of: part_of UBERON:0003100 ! female organism relationship: part_of UBERON:0003100 ! female organism property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/6/68/Scheme_female_reproductive_system-en.svg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000003 "By far, sexual reproduction is the more common pattern among living vertebrate forms and its widespread occurrence suggests that it is the plesiomorphic, or primitive, reproductive mode among the vertebrates.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000726", ontology="VHOG", source="ISBN:978-0792383369 Lombardi J, Comparative vertebrate reproduction (1998) p.43", source="http://bgee.unil.ch/"} [Term] id: UBERON:0000475 name: organism subdivision namespace: uberon def: "Anatomical structure which is a subdivision of a whole organism, consisting of components of multiple anatomical systems, largely surrounded by a contiguous region of integument." [CARO:0000032, CARO:DOS, http://orcid.org/0000-0001-9114-8737] subset: common_anatomy subset: efo_slim subset: pheno_slim subset: uberon_slim subset: upper_level synonym: "anatomic region" EXACT [MA:0002433] synonym: "body part" RELATED [] synonym: "body region" RELATED [FMA:7153] synonym: "cardinal body part" RELATED [FMA:7153] xref: AAO:0010053 xref: AEO:0000032 xref: BILA:0000032 xref: BIRNLEX:7 xref: CALOHA:TS-2084 xref: CARO:0000032 xref: EFO:0000808 xref: EHDAA2:0003032 xref: EMAPA:36031 xref: FBbt:00007009 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:7153 xref: galen:BodyPart xref: HAO:0000032 xref: MA:0002433 xref: MAT:0000293 xref: MESH:D001829 xref: MIAA:0000293 xref: NCIT:C32221 xref: TAO:0001308 xref: TGMA:0001840 xref: UMLS:C0229962 {source="ncithesaurus:Body_Part"} xref: VHOG:0001758 xref: Wikipedia:Body_part xref: XAO:0003013 xref: ZFA:0001308 is_a: UBERON:0010000 {source="CARO"} ! multicellular anatomical structure relationship: has_part UBERON:0000075 {gci_relation="part_of", gci_filler="NCBITaxon:7742"} ! subdivision of skeletal system relationship: has_part UBERON:0034929 {gci_relation="part_of", gci_filler="NCBITaxon:7742"} ! external soft tissue zone relationship: overlaps UBERON:0001009 {gci_filler="NCBITaxon:33213", gci_relation="in_taxon"} ! circulatory system relationship: overlaps UBERON:0001015 {gci_filler="NCBITaxon:6072", gci_relation="in_taxon"} ! musculature relationship: overlaps UBERON:0001016 {gci_filler="NCBITaxon:6072", gci_relation="in_taxon"} ! nervous system relationship: overlaps UBERON:0001434 {gci_filler="NCBITaxon:33213", gci_relation="in_taxon"} ! skeletal system relationship: overlaps UBERON:0002416 {gci_filler="NCBITaxon:6072", gci_relation="in_taxon"} ! integumental system relationship: part_of UBERON:0000468 ! multicellular organism property_value: editor_note "Reflects CARO2. todo - check the inclusion of FMA 'cardinal body part here', and check child terms for consistency" xsd:string property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0000476 name: acellular anatomical structure namespace: uberon def: "Anatomical structure that consists of cell parts and cell substances and together does not constitute a cell or a tissue." [http://orcid.org/0000-0001-9114-8737] subset: common_anatomy subset: vertebrate_core synonym: "acellular anatomical structures" RELATED OMO:0003004 [ZFA:0000382] xref: AAO:0010268 xref: AEO:0000040 xref: BILA:0000040 xref: CARO:0000040 xref: EHDAA2:0003040 xref: FBbt:00007013 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:63863 xref: HAO:0000040 xref: TAO:0000382 xref: TGMA:0001841 xref: XAO:0003162 xref: ZFA:0000382 is_a: UBERON:0000061 ! anatomical structure disjoint_from: UBERON:0010000 {source="CARO"} ! multicellular anatomical structure property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0000477 name: anatomical cluster namespace: uberon def: "Anatomical group whose component anatomical structures lie in close proximity to each other." [FBbt:00007277] subset: common_anatomy subset: upper_level xref: FBbt:00007277 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: VHOG:0001737 is_a: UBERON:0034923 ! disconnected anatomical group property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0000478 name: extraembryonic structure namespace: uberon def: "A multicellular anatomical structure that is associated with an embryo and derived from the zygote from which it develops, but which does not contribute to the embryo proper or to structures that are part of the same organism after embryogenesis." [CARO:DOS, http://orcid.org/0000-0001-9114-8737, https://cedar.bio.indiana.edu/trac/env/ontologies/ticket/279] comment: see also conceptus extraembryonic component in EHDAA2. subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "extra-embryonic structure" EXACT [] synonym: "extraembryonic structures" RELATED OMO:0003004 [ZFA:0000020] synonym: "extraembryonic tissue" RELATED [] xref: AAO:0010020 xref: AEO:0000042 xref: BILA:0000042 xref: CALOHA:TS-2119 xref: CARO:0000042 xref: EHDAA2:0003042 xref: EHDAA:46 xref: FBbt:00005835 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:85537 xref: HAO:0000042 xref: NCIT:C34055 xref: SCTID:314908006 xref: TAO:0000020 xref: TGMA:0001843 xref: UMLS:C1282438 {source="ncithesaurus:Extraembryonic_Structure"} xref: VHOG:0000292 xref: XAO:0004005 xref: ZFA:0000020 is_a: UBERON:0005423 ! developing anatomical structure intersection_of: UBERON:0005423 ! developing anatomical structure intersection_of: part_of UBERON:0016887 ! entire extraembryonic component relationship: existence_starts_and_ends_during UBERON:0000068 {gci_filler="NCBITaxon:6072", gci_relation="in_taxon"} ! embryo stage relationship: part_of UBERON:0016887 ! entire extraembryonic component [Term] id: UBERON:0000479 name: tissue namespace: uberon def: "Multicellular anatomical structure that consists of many cells of one or a few types, arranged in an extracellular matrix such that their long-range organisation is at least partly a repetition of their short-range organisation." [CARO:0000043] subset: common_anatomy subset: pheno_slim subset: upper_level synonym: "portion of tissue" EXACT [CARO:0000043] synonym: "simple tissue" NARROW [AEO:0000043] synonym: "tissue portion" EXACT [] xref: AAO:0000607 xref: AAO:0010054 xref: AEO:0000043 xref: BILA:0000043 xref: BIRNLEX:19 xref: CALOHA:TS-2090 xref: CARO:0000043 xref: EHDAA2:0003043 xref: EMAPA:35868 xref: FBbt:00007003 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:9637 xref: galen:Tissue xref: HAO:0000043 xref: MA:0003002 xref: MESH:D014024 xref: NCIT:C12801 xref: TAO:0001477 xref: TGMA:0001844 xref: UMLS:C0040300 {source="ncithesaurus:Tissue"} xref: VHOG:0001757 xref: WBbt:0005729 xref: XAO:0003040 xref: ZFA:0001477 is_a: UBERON:0010000 {source="CARO"} ! multicellular anatomical structure relationship: has_part GO:0031012 ! extracellular matrix relationship: part_of UBERON:0000468 ! multicellular organism property_value: editor_note "changed label and definition to reflect CARO2" xsd:string property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0000481 name: multi-tissue structure namespace: uberon def: "Anatomical structure that has as its parts two or more portions of tissue of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona-fide boundaries from other distinct structural units of different types." [CARO:0000055, http://orcid.org/0000-0001-9114-8737] subset: common_anatomy subset: upper_level synonym: "multi-tissue structures" RELATED OMO:0003004 [ZFA:0001488] xref: AAO:0010048 xref: AEO:0000055 xref: BILA:0000055 xref: CARO:0000055 xref: EHDAA2:0003055 xref: FBbt:00007010 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: HAO:0000055 xref: TAO:0001488 xref: TGMA:0001847 xref: VHOG:0001762 xref: XAO:0003037 xref: ZFA:0001488 is_a: UBERON:0010000 {source="CARO"} ! multicellular anatomical structure relationship: has_part UBERON:0000479 ! tissue relationship: part_of NCBITaxon:6072 {gci_filler="NCBITaxon:6072", gci_relation="in_taxon"} ! Eumetazoa property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0000483 name: epithelium namespace: uberon def: "Portion of tissue, that consists of one or more layers of epithelial cells connected to each other by cell junctions and which is underlain by a basal lamina. Examples: simple squamous epithelium, glandular cuboidal epithelium, transitional epithelium, myoepithelium[CARO]." [http://orcid.org/0000-0001-9114-8737, Wikipedia:Epithelium] comment: Editor note: surface epithelium may contain non-epithelial cells, such as melanocytes, lymphocytes and dendritic cells, within the sheet of epithelial cells. Do we consider these part of the epithelium, or located-in it? subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "epithelial tissue" EXACT [] synonym: "portion of epithelium" EXACT [FMA:9639] xref: AAO:0000144 xref: AAO:0010055 xref: AEO:0000066 xref: BILA:0000066 xref: BTO:0000416 xref: CALOHA:TS-0288 xref: CARO:0000066 xref: EHDAA2:0003066 xref: EMAPA:32738 xref: FBbt:00007005 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:9639 xref: GAID:402 xref: HAO:0000066 xref: MA:0003060 xref: MESH:D004848 xref: NCIT:C12710 xref: SCTID:31610004 xref: TAO:0001486 xref: UMLS:C0014609 {source="ncithesaurus:Epithelium"} xref: VHOG:0000387 xref: Wikipedia:Epithelium xref: XAO:0003045 xref: ZFA:0001486 is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000479 ! tissue intersection_of: UBERON:0000479 ! tissue intersection_of: composed_primarily_of CL:0000066 ! epithelial cell union_of: UBERON:0000486 ! multilaminar epithelium union_of: UBERON:0000490 ! unilaminar epithelium relationship: composed_primarily_of CL:0000066 ! epithelial cell relationship: has_part GO:0005911 ! cell-cell junction relationship: has_part UBERON:0005769 ! basement membrane of epithelium relationship: only_in_taxon NCBITaxon:33208 {source="http://palaeos.com/metazoa/porifera/homoscleromorpha.html"} ! Metazoa property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/8/8f/Illu_epithelium.jpg" xsd:anyURI property_value: UBPROP:0000003 "The two basic types of metazoan tissue are epithelial and connective. The simplest metazoans, and developmental stages of many primitive invertebrates, consist solely of these two layers. Thus, epithelial and connective tissues may be the primary (original) tissues of metazoans, and both are important in the functional organization of animals.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000387", ontology="VHOG", source="ISBN:978-0030259821 Ruppert EE, Fox RS, Barnes RD, Invertebrate zoology: a functional evolutionary approach (2003) p.59", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "epithelial" xsd:string [Term] id: UBERON:0000484 name: simple cuboidal epithelium namespace: uberon def: "Unilaminar epithelium that consists of a single layer of cuboidal cells." [http://orcid.org/0000-0001-9114-8737, Wikipedia:Simple_cuboidal_epithelium] subset: uberon_slim subset: vertebrate_core synonym: "epithelium simplex cuboideum" EXACT [] synonym: "simple cuboidal epithelia" RELATED OMO:0003004 [ZFA:0001497] xref: AAO:0010064 xref: AEO:0000067 xref: BILA:0000067 xref: CARO:0000067 xref: EHDAA2:0003067 xref: FMA:45566 xref: HAO:0000067 xref: NCIT:C33553 xref: TAO:0001497 xref: UMLS:C0836134 {source="ncithesaurus:Simple_Cuboidal_Epithelium"} xref: Wikipedia:Simple_cuboidal_epithelium xref: XAO:0004009 xref: ZFA:0001497 is_a: UBERON:0000490 ! unilaminar epithelium is_a: UBERON:0010077 ! cuboidal epithelium property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/d/d0/Gray1133.png" xsd:anyURI property_value: editor_note "needs to be synchronized with CL - there is no distinct cuboidal cell in CL" xsd:string [Term] id: UBERON:0000485 name: simple columnar epithelium namespace: uberon def: "Unilaminar epithelium, which consists of a single layer of columnar cells. Examples: ciliated columnar epithelium, gastric epithelium, microvillus columnar epithelium.[FMA]." [FMA:FMA, http://orcid.org/0000-0001-9114-8737, Wikipedia:Simple_columnar_epithelium] subset: uberon_slim subset: vertebrate_core synonym: "columnar epithelium" BROAD [EHDAA2:0003068] synonym: "columnar epithlium" BROAD [AEO:0000068] synonym: "epithelium simplex columnare" EXACT [] synonym: "simple columnar epithelia" RELATED OMO:0003004 [ZFA:0001496] synonym: "simple columnar epithelium" EXACT [] xref: AAO:0010063 xref: AEO:0000068 xref: BILA:0000068 xref: CARO:0000068 xref: EHDAA2_RETIRED:0003068 xref: FBbt:00007027 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:45567 xref: HAO:0000068 xref: NCIT:C33552 xref: SCTID:32210007 xref: TAO:0001496 xref: UMLS:C0836135 {source="ncithesaurus:Simple_Columnar_Epithelium"} xref: Wikipedia:Simple_columnar_epithelium xref: XAO:0004008 xref: ZFA:0001496 is_a: UBERON:0000490 ! unilaminar epithelium is_a: UBERON:0012274 ! columnar epithelium property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/8/8b/Gray1059.png" xsd:anyURI [Term] id: UBERON:0000486 name: multilaminar epithelium namespace: uberon def: "Epithelium which consists of more than one layer of epithelial cells that may or may not be in contact with a basement membrane. Examples: keratinized stratified squamous epithelium, ciliated stratified columnar epithelium.[FMA]." [FMA:FMA, http://orcid.org/0000-0001-9114-8737, Wikipedia:Stratified_epithelium] subset: uberon_slim subset: vertebrate_core synonym: "laminated epithelium" RELATED [BTO:0002074] synonym: "stratified epithelium" EXACT [] xref: AAO:0010059 xref: AEO:0000069 xref: BILA:0000069 xref: BTO:0002074 xref: CARO:0000069 xref: EHDAA2:0003069 xref: FMA:45562 xref: HAO:0000069 xref: NCIT:C33622 xref: SCTID:309044005 xref: TAO:0001494 xref: UMLS:C0682575 {source="ncithesaurus:Stratified_Epithelium"} xref: Wikipedia:Stratified_epithelium xref: XAO:0004006 xref: ZFA:0001494 is_a: UBERON:0000483 ! epithelium property_value: UBPROP:0000001 "Epithelium that consists of more than one layer of epithelial cells.[CARO]" xsd:string {date_retrieved="2012-06-20", external_class="CARO:0000069", ontology="CARO", source="FMA:45562", source="http://orcid.org/0000-0001-9114-8737"} [Term] id: UBERON:0000487 name: simple squamous epithelium namespace: uberon def: "Unilaminar epithelium which consists of a single layer of squamous cells. Examples: pulmonary alveolar epithelium, endothelium.[FMA]." [FMA:45565, http://orcid.org/0000-0001-9114-8737, Wikipedia:Simple_squamous_epithelium] subset: uberon_slim subset: vertebrate_core synonym: "epithelium simplex squamosum" EXACT [] synonym: "simple squamous epithelia" RELATED OMO:0003004 [ZFA:0001498] xref: AAO:0010066 xref: AEO:0000070 xref: BILA:0000070 xref: BTO:0002073 xref: CARO:0000070 xref: EHDAA2:0003070 xref: FMA:45565 xref: HAO:0000070 xref: NCIT:C13178 xref: TAO:0001498 xref: UMLS:C0836133 {source="ncithesaurus:Simple_Squamous_Epithelium"} xref: Wikipedia:Simple_squamous_epithelium xref: XAO:0004010 xref: ZFA:0001498 is_a: UBERON:0000490 ! unilaminar epithelium is_a: UBERON:0006914 ! squamous epithelium intersection_of: UBERON:0000490 ! unilaminar epithelium intersection_of: has_part CL:0000076 ! squamous epithelial cell property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/8/8f/Illu_epithelium.jpg" xsd:anyURI property_value: UBPROP:0000001 "Unilaminar epithelium that consists of a single layer of squamous cells.[CARO]" xsd:string {date_retrieved="2012-06-20", external_class="CARO:0000070", ontology="CARO", source="FMA:45565", source="http://orcid.org/0000-0001-9114-8737"} [Term] id: UBERON:0000488 name: atypical epithelium namespace: uberon def: "Epithelium that consists of epithelial cells not arranged in one ore more layers." [http://orcid.org/0000-0001-9114-8737] subset: vertebrate_core synonym: "atypical epithelia" RELATED OMO:0003004 [ZFA:0001493] synonym: "heterogenous epithelium" EXACT [] xref: AAO:0010057 xref: AEO:0000071 xref: BILA:0000071 xref: CARO:0000071 xref: EHDAA2:0003071 xref: FMA:61741 xref: HAO:0000071 xref: TAO:0001493 xref: XAO:0004004 xref: ZFA:0001493 is_a: UBERON:0000483 ! epithelium [Term] id: UBERON:0000489 name: cavitated compound organ namespace: uberon def: "Compound organ that contains one or more macroscopic anatomical spaces." [http://orcid.org/0000-0001-9114-8737] subset: organ_slim subset: upper_level synonym: "cavitated compound organs" RELATED OMO:0003004 [ZFA:0001490] synonym: "cavitated organ" EXACT [FMA:55671] xref: AAO:0010016 xref: AEO:0000072 xref: BILA:0000072 xref: CARO:0000072 xref: EHDAA2:0003072 xref: FMA:55671 xref: HAO:0000072 xref: TAO:0001490 xref: TGMA:0001857 xref: VHOG:0001730 xref: XAO:0003165 xref: ZFA:0001490 is_a: UBERON:0003103 ! compound organ intersection_of: UBERON:0003103 ! compound organ intersection_of: has_part UBERON:0002553 ! anatomical cavity relationship: has_part UBERON:0002553 ! anatomical cavity property_value: curator_notes "this class was introduced for consistency with CARO, however, it has yet to be used in this or other ontologies. It may be retired in the future" xsd:string [Term] id: UBERON:0000490 name: unilaminar epithelium namespace: uberon def: "Epithelium which consists of a single layer of epithelial cells. Examples: endothelium, mesothelium, glandular squamous epithelium.[FMA]." [FMA:45561, http://orcid.org/0000-0001-9114-8737] subset: vertebrate_core synonym: "simple epithelium" EXACT [FMA:45561] synonym: "unilaminar epithelia" RELATED OMO:0003004 [ZFA:0001495] xref: AAO:0010062 xref: AEO:0000073 xref: BILA:0000073 xref: BTO:0002073 xref: CARO:0000073 xref: EHDAA2:0003073 xref: FMA:45561 xref: HAO:0000073 xref: NCIT:C33554 xref: SCTID:309043004 xref: TAO:0001495 xref: UMLS:C0682574 {source="ncithesaurus:Simple_Epithelium"} xref: XAO:0004007 xref: ZFA:0001495 is_a: UBERON:0000483 ! epithelium property_value: editor_note "consider adding disjointness axiom between unilaminar and multilaminar - but note that this will render EHDAA2:0003244 (chorionic trophoblast) unsatisfiable" xsd:string property_value: UBPROP:0000001 "Epithelium that consists of a single layer of epithelial cells.[CARO]" xsd:string {date_retrieved="2012-06-20", external_class="CARO:0000073", ontology="CARO", source="FMA:45561", source="http://orcid.org/0000-0001-9114-8737"} [Term] id: UBERON:0000912 name: mucus namespace: uberon def: "Mucus is a bodily fluid consisting of a slippery secretion of the lining of the mucous membranes in the body. It is a viscous colloid containing antiseptic enzymes (such as lysozyme) and immunoglobulins. Mucus is produced by goblet cells in the mucous membranes that cover the surfaces of the membranes. It is made up of mucins and inorganic salts suspended in water." [Wikipedia:Mucus] xref: CALOHA:TS-2144 xref: ENVO:02000040 xref: FMA:66938 xref: GAID:1164 xref: galen:Mucus xref: MESH:D009093 xref: NCIT:C13259 xref: UMLS:C0026727 {source="ncithesaurus:Mucus"} xref: Wikipedia:Mucus is_a: UBERON:0000456 ! secretion of exocrine gland is_a: UBERON:0006314 ! bodily fluid relationship: has_part CHEBI:37395 ! mucopolysaccharide relationship: has_quality PATO:0000998 ! viscous relationship: produced_by UBERON:0000344 ! mucosa property_value: UBPROP:0000007 "mucoid" xsd:string property_value: UBPROP:0000007 "mucous" xsd:string [Term] id: UBERON:0000915 name: thoracic segment of trunk namespace: uberon def: "Subdivision of trunk that lies between the head and the abdomen." [http://orcid.org/0000-0002-6601-2165] subset: uberon_slim synonym: "anterior subdivision of trunk" RELATED [] synonym: "thorax" EXACT [MA:0000022] synonym: "upper body" RELATED [] synonym: "upper trunk" RELATED [FMA:259209] xref: EMAPA:35862 xref: FMA:259209 xref: MA:0000022 xref: SCTID:302551006 xref: Wikipedia:Thorax is_a: UBERON:0009569 {source="FMA"} ! subdivision of trunk is_a: UBERON:0011676 ! subdivision of organism along main body axis intersection_of: UBERON:0011676 ! subdivision of organism along main body axis intersection_of: has_skeleton UBERON:0014477 ! thoracic skeleton relationship: has_skeleton UBERON:0014477 ! thoracic skeleton property_value: curator_notes "note that we use the slightly verbose term 'thoracic segment of trunk' to avoid confusuon with insect thorax. todo - taxonomic constraints. Also, in FMA 'thorax' is a synonym for chest" xsd:string property_value: RO:0002171 UBERON:0000026 property_value: RO:0002171 UBERON:0000033 property_value: RO:0002171 UBERON:0002417 [Term] id: UBERON:0000916 name: abdomen namespace: uberon def: "The subdivision of the vertebrate body between the thorax and pelvis. The ventral part of the abdomen contains the abdominal cavity and visceral organs. The dorsal part includes the abdominal section of the vertebral column." [http://orcid.org/0000-0002-6601-2165] subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "abdominopelvic region" EXACT [FMA:9577] synonym: "abdominopelvis" EXACT [FMA:9577] synonym: "adult abdomen" RELATED [] synonym: "belly" RELATED [] synonym: "celiac region" RELATED [] xref: BTO:0000020 xref: CALOHA:TS-0001 xref: EFO:0000968 xref: EMAPA:35102 xref: EV:0100011 xref: FMA:9577 xref: GAID:16 xref: galen:Abdomen xref: MA:0000029 xref: MAT:0000298 xref: MESH:D000005 xref: MIAA:0000298 xref: SCTID:302553009 xref: Wikipedia:Abdomen is_a: UBERON:0009569 ! subdivision of trunk relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0002417 {source="MA"} ! abdominal segment of trunk property_value: editor_note "Vertebrate specific. In arthropods 'abdomen' is the most distal section of the body which lies behind the thorax or cephalothorax. If need be we can introduce some grouping class" xsd:string property_value: UBPROP:0000007 "abdominal" xsd:string property_value: UBPROP:0000007 "celiac" xsd:string [Term] id: UBERON:0000922 name: embryo namespace: uberon def: "Anatomical entity that comprises the organism in the early stages of growth and differentiation that are characterized by cleavage, the laying down of fundamental tissues, and the formation of primitive organs and organ systems. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant." [BTO:0000379, FB:FBrf0039741, FB:FBrf0041814, GO:0009790, Wikipedia:Embryo] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "developing organism" RELATED [BILA:0000056] synonym: "developmental tissue" RELATED [] synonym: "embryonic organism" EXACT [BILA:0000056] xref: AAO:0011035 xref: AEO:0000169 xref: BILA:0000056 xref: BSA:0000039 xref: BTO:0000379 xref: CALOHA:TS-0229 xref: EFO:0001367 xref: EHDAA2:0000002 xref: EHDAA2_RETIRED:0003236 xref: EHDAA:38 xref: EMAPA:16039 xref: FBbt:00000052 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:69068 xref: GAID:963 xref: http://neurolex.org/wiki/Category\:Embryonic_organism xref: IDOMAL:0000646 {sssom:mapping_justification="vocab:ManualMappingCuration", sssom:author_id="https://orcid.org/0000-0003-4423-4370", sssom:mapping_provider="https://github.com/biopragmatics/biomappings"} xref: MAT:0000226 xref: MESH:D004622 xref: MIAA:0000019 xref: NCIT:C28147 xref: OGEM:000001 xref: SCTID:57991002 xref: UMLS:C0013935 {source="ncithesaurus:Embryo"} xref: VHOG:0001766 xref: Wikipedia:Embryo xref: XAO:0000113 xref: ZFA:0000103 is_a: UBERON:0000468 ! multicellular organism intersection_of: UBERON:0000468 ! multicellular organism intersection_of: existence_ends_with UBERON:0000068 ! embryo stage intersection_of: existence_starts_with UBERON:0000068 ! embryo stage relationship: existence_ends_with UBERON:0000068 ! embryo stage relationship: existence_starts_with UBERON:0000068 ! embryo stage property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/2/2d/Wrinkledfrog_embryos.jpg" xsd:anyURI property_value: seeAlso "https://github.com/obophenotype/uberon/issues/503" xsd:anyURI property_value: UBPROP:0000007 "embryonic" xsd:string property_value: UBPROP:0000012 "Obsoleted in ZFA. Note that embryo is not classified as an embryonic structure - an embryonic structure is only the parts of an embryo" xsd:string {external_ontology="ZFA"} [Term] id: UBERON:0000923 name: germ layer namespace: uberon def: "A layer of cells produced during the process of gastrulation during the early development of the animal embryo, which is distinct from other such layers of cells, as an early step of cell differentiation. The three types of germ layers are the endoderm, ectoderm, and mesoderm." [https://github.com/obophenotype/uberon/issues/203, Wikipedia:Germ_layer] comment: Classically the germ layers are ectoderm, mesoderm and endoderm. Alternatively: primary = ectoderm, endoderm; secondary=mesoderm; tertiary=dorsal mesoderm, NC[https://github.com/obophenotype/uberon/wiki/The-neural-crest] subset: uberon_slim subset: vertebrate_core synonym: "embryonic germ layer" RELATED [] synonym: "embryonic germ layers" RELATED [] synonym: "embryonic tissue" BROAD [FMA:69069] synonym: "germinal layer" EXACT [ncithesaurus:Germinal_Layer] synonym: "primary germ layer" NARROW [GO:0001704, ZFA:0001122] xref: AAO:0000480 xref: BILA:0000035 xref: BTO:0000556 xref: EMAPA:36033 xref: FBbt:00000110 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:69069 xref: GAID:1303 xref: MESH:D005855 xref: NCIT:C12950 xref: NCIT:C54105 xref: TAO:0001122 xref: UMLS:C0920502 {source="ncithesaurus:Embryonic_Tissue"} xref: UMLS:C1708239 {source="ncithesaurus:Germinal_Layer"} xref: VHOG:0001223 xref: Wikipedia:Germ_layer xref: XAO:0003011 xref: ZFA:0001122 is_a: UBERON:0010316 ! germ layer / neural crest relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa property_value: UBPROP:0000003 "The Bilateria are triploblastic (with true endoderm, mesoderm, and ectoderm) (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001223", ontology="VHOG", source="ISBN:978-0878932504 Gilbert SF, Developmental Biology (2006) Limb development and evolution, p.722", source="http://bgee.unil.ch/"} [Term] id: UBERON:0000924 name: ectoderm namespace: uberon def: "Primary germ layer that is the outer of the embryo's three germ layers and gives rise to epidermis and neural tissue." [Wikipedia:Ectoderm] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "embryonic ectoderm" EXACT [VHOG:0000153] xref: AAO:0000137 xref: BILA:0000036 xref: BTO:0000315 xref: CALOHA:TS-0216 xref: EFO:0000414 xref: EHDAA2:0000428 xref: EMAPA:16069 xref: EV:0100003 xref: FBbt:00000111 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:69070 xref: GAID:1304 xref: MAT:0000155 xref: MAT:0000173 xref: MESH:D004475 xref: MIAA:0000173 xref: NCIT:C12703 xref: SCTID:362851007 xref: TAO:0000016 xref: UMLS:C0013574 {source="ncithesaurus:Ectoderm"} xref: VHOG:0000153 xref: Wikipedia:Ectoderm xref: XAO:0000001 xref: ZFA:0000016 is_a: UBERON:0000923 ! germ layer relationship: develops_from UBERON:0006601 ! presumptive ectoderm relationship: has_part CL:0000221 ! ectodermal cell relationship: immediate_transformation_of UBERON:0006601 {source="Bgee:AN"} ! presumptive ectoderm property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/1/19/Gray32.png" xsd:anyURI property_value: UBPROP:0000001 "Primary germ layer that is the outer of the embryonic germ layers and gives rise to epidermis and neural tissue.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000137", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000003 "The Bilateria are triploblastic (with true endoderm, mesoderm, and ectoderm) (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000153", ontology="VHOG", source="ISBN:978-0878932504 Gilbert SF, Developmental Biology (2006) Limb development and evolution, p.722", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "ectodermal" xsd:string [Term] id: UBERON:0000925 name: endoderm namespace: uberon def: "Primary germ layer that lies remote from the surface of the embryo and gives rise to internal tissues such as gut." [Wikipedia:Endoderm] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "entoderm" RELATED DEPRECATED [DOI:10.5962/bhl.title.1013] xref: AAO:0000139 xref: BILA:0000038 xref: BTO:0000800 xref: CALOHA:TS-0273 xref: EFO:0002545 xref: EHDAA2:0000436 xref: EMAPA:16062 xref: EV:0100005 xref: FBbt:00000125 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:69071 xref: GAID:1305 xref: MAT:0000175 xref: MESH:D004707 xref: MIAA:0000175 xref: NCIT:C12706 xref: SCTID:362855003 xref: TAO:0000017 xref: UMLS:C0014144 {source="ncithesaurus:Endoderm"} xref: VHOG:0000154 xref: Wikipedia:Endoderm xref: XAO:0000090 xref: ZFA:0000017 is_a: UBERON:0000923 ! germ layer relationship: develops_from UBERON:0006595 ! presumptive endoderm relationship: has_part CL:0000223 ! endodermal cell relationship: immediate_transformation_of UBERON:0006595 {source="Bgee:AN"} ! presumptive endoderm property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/c/c0/Endoderm2.png" xsd:anyURI property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/d/df/Gray10.png" xsd:anyURI property_value: UBPROP:0000003 "The Bilateria are triploblastic (with true endoderm, mesoderm, and ectoderm) (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000154", ontology="VHOG", source="ISBN:978-0878932504 Gilbert SF, Developmental Biology (2006) Limb development and evolution, p.722", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "endodermal" xsd:string [Term] id: UBERON:0000926 name: mesoderm namespace: uberon alt_id: UBERON:0003263 def: "The middle germ layer of the embryo, between the endoderm and ectoderm." [Wikipedia:Mesoderm] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "embryonic mesoderm" RELATED [VHOG:0000152] synonym: "entire mesoderm" RELATED [https://orcid.org/0000-0002-6601-2165, SCTID:362854004] synonym: "mesodermal mantle" RELATED [] xref: AAO:0000304 xref: BILA:0000037 xref: BTO:0000839 xref: CALOHA:TS-0623 xref: EFO:0001981 xref: EHDAA2:0001128 xref: EHDAA:124 xref: EHDAA:160 xref: EHDAA:183 xref: EMAPA:16083 xref: EV:0100006 xref: FBbt:00000126 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:69072 xref: GAID:522 xref: MAT:0000174 xref: MESH:D008648 xref: MIAA:0000174 xref: NCIT:C12750 xref: SCTID:362854004 xref: TAO:0000041 xref: UMLS:C0025485 {source="ncithesaurus:Mesoderm"} xref: VHOG:0000152 xref: Wikipedia:Mesoderm xref: XAO:0000050 xref: ZFA:0000041 is_a: UBERON:0000923 {notes="sometimes not considered primary"} ! germ layer relationship: develops_from UBERON:0006603 ! presumptive mesoderm relationship: has_part CL:0000222 ! mesodermal cell relationship: immediate_transformation_of UBERON:0006603 {source="Bgee:AN"} ! presumptive mesoderm property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/e/e8/Mesoderm.png" xsd:anyURI property_value: RO:0002161 NCBITaxon:6040 property_value: UBPROP:0000001 "Primary germ layer that is the middle of the embryonic germ layers.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000304", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000003 "The Bilateria are triploblastic (with true endoderm, mesoderm, and ectoderm) (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000152", ontology="VHOG", source="ISBN:978-0878932504 Gilbert SF, Developmental Biology (2006) Limb development and evolution, p.722", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "mesodermal" xsd:string property_value: UBPROP:0000008 "sponges do not seem to have a mesoderm and accordingly Amphimedon lacks transcription factors involved in mesoderm development (Fkh, Gsc, Twist, Snail)[http://www.nature.com/nature/journal/v466/n7307/full/nature09201.html]. Mesoderm may not be homologous across verteberates" xsd:string {source="https://github.com/obophenotype/uberon/wiki/The-neural-crest"} [Term] id: UBERON:0000930 name: stomodeum namespace: uberon def: "Anterior part of the embryonic digestive tract that develops into a mouth. The stomodeum includes as parts an invagination of the ectoderm and the stomodeal cavity." [http://orcid.org/0000-0002-6601-2165, https://github.com/obophenotype/uberon/issues/326, Wikipedia:Stomodeum] subset: grouping_class subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "mouth pit" RELATED [EMAPA:16263] synonym: "mouth primordium" EXACT [XAO:0000269] synonym: "oral ectoderm" RELATED [ZFA:0001290, ZFIN:ZDB-PUB-100726-23] synonym: "oral pit" RELATED [EMAPA:16263] synonym: "primitive oral cavity" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "stomatodeum" EXACT [Wikipedia:Stomodeum] synonym: "stomodaeum" EXACT [] synonym: "stomodeal-hypophyseal primordium" BROAD [XAO:0000269] xref: BTO:0004224 xref: EHDAA2:0001929 xref: EMAPA:16263 xref: FBbt:00000439 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:295846 xref: NCIT:C34306 xref: TAO:0001290 xref: TGMA:0000135 xref: UMLS:C1514977 {source="ncithesaurus:Stomodeum"} xref: Wikipedia:Stomodeum xref: XAO:0000269 xref: ZFA:0001290 is_a: UBERON:0013522 ! subdivision of tube relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of UBERON:0000924 ! ectoderm relationship: part_of UBERON:0035804 ! future mouth property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/9/93/Gray977.png" xsd:anyURI property_value: editor_note "consider indicating location. e.g. anterior. Note some AOs place this as part of oral opening, but it's not clear when this structure comes into existence" xsd:string property_value: UBPROP:0000001 "Anterior part of the embryonic alimentary canal formed as an invagination of the ectoderm; the future mouth.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001290", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "the primordial mouth region of the developing head, initially a midline ectodermal depression between the forebrain bulge (cranially) and the heart bulge (caudally) and between the maxillary and mandibular components of the first pharyngeal arch; the stomodeum is separated from the anterior end of the foregut by the buccopharyngeal membrane; the mouth is developed partly from the stomodeum, and partly from the floor of the anterior portion of the foregut; the lips, teeth, and gums are formed from the walls of the stomodeum, but the tongue is developed in the floor of the pharynx" xsd:string {source="MP:0012522", taxon="NCBITaxon:40674"} property_value: UBPROP:0000007 "stomodeal" xsd:string property_value: UBPROP:0000008 "This class groups together disparate structures as all being the anterior part of the early metazoan digestive tract and precursor of the mouth. However, the developmental processes vary, so this class may be split in future. E.g. in mammals it is a rostral depression surrounded by prominences. Outgrowth of the prominences produces a stomodeal cavity." xsd:string [Term] id: UBERON:0000931 name: proctodeum namespace: uberon def: "Inward fold on the surface of the embryonic ectoderm that develops into an ectodermal terminal part of the digestive tract." [https://github.com/obophenotype/uberon/issues/685, https://sourceforge.net/p/fbbtdv/tickets/52, ZFA:0000066] subset: uberon_slim synonym: "amnioproctodeal invagination" NARROW [FBbt:00000123] synonym: "anal pit" RELATED [VHOG:0000139] synonym: "anus porus" RELATED [XAO:0001019] synonym: "embryonic proctodaeum" EXACT [] synonym: "proctodaeum" EXACT [] xref: AAO:0011087 xref: EHDAA2:0000121 xref: EMAPA:25038 xref: FBbt:00000123 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: NCIT:C34278 xref: TAO:0000066 xref: UMLS:C0231054 {source="ncithesaurus:Proctodeum"} xref: VHOG:0000139 xref: Wikipedia:Proctodeum xref: XAO:0001019 xref: ZFA:0000066 is_a: UBERON:0016566 {source="EHDAA2"} ! pit relationship: develops_from UBERON:0000924 ! ectoderm relationship: has_potential_to_develop_into UBERON:0001353 ! anal region relationship: located_in UBERON:0012469 {source="EHDAA2"} ! external anal region relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of UBERON:0007026 ! presumptive gut property_value: editor_note "removed WBbt:0006795 'proctodeum' - junction between the alimentary and genital tracts in the male." xsd:string property_value: seeAlso "https://github.com/obophenotype/uberon/issues/685" xsd:anyURI property_value: UBPROP:0000001 "An inward fold on the surface of the embryonic ectoderm that develops into part of the anal passage.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000066", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "Inward fold on the surface of the embryonic ectoderm that develops into part of the anal passage.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0011087", ontology="AAO", source="ZFA:0000066"} property_value: UBPROP:0000007 "proctodeal" xsd:string property_value: x_1.1:contributor https://github.com/ANiknejad property_value: x_1.1:contributor https://github.com/cmungall property_value: x_1.1:contributor https://github.com/dosumis property_value: x_1.1:contributor https://github.com/mmc46 [Term] id: UBERON:0000945 name: stomach namespace: uberon def: "An expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ. A stomach is lined, in whole or in part by a glandular epithelium." [https://orcid.org/0000-0002-6601-2165, ISBN:0073040584, Wikipedia:Stomach] subset: efo_slim subset: human_reference_atlas subset: major_organ subset: organ_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "anterior intestine" RELATED [] synonym: "gaster" RELATED [BTO:0001307] synonym: "mesenteron" RELATED [] synonym: "stomach chamber" NARROW [] synonym: "ventriculus" RELATED OMO:0003011 [Wikipedia:Stomach] xref: AAO:0000579 xref: ANISEED:1235297 xref: BTO:0001307 xref: CALOHA:TS-0980 xref: EFO:0000837 xref: EHDAA2:0001915 xref: EHDAA:2993 xref: EMAPA:17021 xref: EV:0100070 xref: FMA:7148 xref: GAID:293 xref: galen:Stomach xref: MA:0000353 xref: MAT:0000051 xref: MESH:D013270 xref: MIAA:0000051 xref: NCIT:C12391 xref: SCTID:181246003 xref: TAO:0002121 xref: UMLS:C0038351 {source="ncithesaurus:Stomach"} xref: VHOG:0000408 xref: Wikipedia:Stomach xref: XAO:0000128 is_a: UBERON:0004921 {source="cjm"} ! subdivision of digestive tract is_a: UBERON:0010039 {source="cjm"} ! food storage organ relationship: capable_of GO:0001696 {evidence="ISBN:0486692132"} ! gastric acid secretion relationship: contributes_to_morphology_of UBERON:0001007 ! digestive system relationship: only_in_taxon NCBITaxon:7776 {notes="absent in lampreys and hagfishes", source="ISBN:0073040584"} ! Gnathostomata relationship: part_of UBERON:0001041 ! foregut property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/e/e0/Stomach_diagram.svg" xsd:anyURI property_value: RO:0002161 NCBITaxon:7864 {source="Wikipedia"} property_value: RO:0002161 NCBITaxon:7878 {source="Wikipedia"} property_value: RO:0002161 NCBITaxon:7955 {source="ZFA"} property_value: RO:0002161 NCBITaxon:9259 {source="Wikipedia"} property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Portion of alimentary canal with increased circular and longitudinal smooth muscle. Bounded posteriorly by the pyloric sphincter. Mucosal lining has increased folding.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000579", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000003 "It appears that the stomach has an ancient origin. The stomach first appears in the fish lineage. The prevertebrate chordates do not have a true stomach, whereas the cartilaginous and bony fish do. Although most fish do have a true stomach, some fish species appear to have lost the stomach secondarily. The remaining vertebrate lineages do have a true stomach (at least in the adult animal), although there is great variation in the size and shape of the stomach.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000408", ontology="VHOG", source="DOI:10.1046/j.1525-142x.2000.00076.x Smith DM, Grasty RC, Theodosiou NA, Tabin CJ, Nascone-Yoder NM, Evolutionary relationships between the amphibian, avian, and mammalian stomachs. Evolution and development (2000)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "We restrict this to the vertebrate specific structure - see the grouping class 'food storage organ' for analogous structures in other species. Teleosts: Zebrafish is functionally stomach-less, but may retain ontogenic footprint. Although the precise shape and size of the stomach varies widely among different vertebrates, the relative positions of the oesophageal and duodenal openings remain relatively constant. As a result, the organ always curves somewhat to the left before curving back to meet the pyloric sphincter. However, lampreys, hagfishes, chimaeras, lungfishes, and some teleost fish have no stomach at all, with the oesophagus opening directly into the intestine. The gastric lining is usually divided into two regions, an anterior portion lined by fundic glands, and a posterior with pyloric glands. Cardiac glands are unique to mammals, and even then are absent in a number of species. The distributions of these glands vary between species, and do not always correspond with the same regions as in man. Furthermore, in many non-human mammals, a portion of the stomach anterior to the cardiac glands is lined with epithelium essentially identical to that of the oesophagus. Ruminants, in particular, have a complex stomach, the first three chambers of which are all lined with oesophageal mucosa" xsd:string {source="WP:Stomach#In_other_animals"} [Term] id: UBERON:0000947 name: aorta namespace: uberon def: "The main trunk of the systemic arterial system that carries blood from the heart to all the organs and other structures of the body, bringing oxygenated blood to all parts of the body in the systemic circulation." [http://orcid.org/0000-0002-6601-2165, ISBN:0-683-40008-8, MESH:A07.231.114.056, MP:0000272, Wikipedia:Aorta] subset: efo_slim subset: grouping_class subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "arteria maxima" RELATED OMO:0003011 [Wikipedia:Aorta] synonym: "dorsal aorta" NARROW SENSU [Wikipedia:Aorta#In_other_animals, ZFA:0000014] synonym: "trunk of aortic tree" EXACT [] synonym: "trunk of systemic arterial tree" EXACT [] xref: AAO:0010213 xref: BTO:0000135 xref: CALOHA:TS-0046 xref: EFO:0000265 xref: EMAPA:18601 xref: EV:0100027 xref: FMA:3734 xref: GAID:469 xref: galen:Aorta xref: MA:0000062 xref: MAT:0000035 xref: MESH:D001011 xref: MIAA:0000035 xref: NCIT:C12669 xref: SCTID:181298001 xref: UMLS:C0003483 {source="ncithesaurus:Aorta"} xref: VHOG:0001523 xref: Wikipedia:Aorta xref: XAO:0003010 is_a: UBERON:0003509 {source="MA"} ! arterial blood vessel is_a: UBERON:0003519 ! thoracic cavity blood vessel is_a: UBERON:0013768 ! great vessel of heart relationship: connected_to UBERON:0002084 ! heart left ventricle relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0010191 {source="EHDAA2"} ! aortic system property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/9/91/Aorta_scheme.jpg" xsd:anyURI property_value: editor_note "This class is currently a mixed bag, encompassing (1) the entirety of the mammalian aorta together with (2) the developmental and phylogenetic homologs of its segments: the ventral aorta and dorsal aortae." xsd:string {source="WP"} property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "The main artery of the circulatory system which carries oxygenated blood from the heart to all the arteries of the body except those of the lungs.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010213", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000003 "When vertebrates first appeared, they must have possessed a ventral and dorsal aorta with aortic arches between them.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001523", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.620", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "aortic" xsd:string property_value: UBPROP:0000008 "All amniotes have a broadly similar arrangement to that of humans, albeit with a number of individual variations. In fish, however, there are two separate vessels referred to as aortas. The ventral aorta carries de-oxygenated blood from the heart to the gills; part of this vessel forms the ascending aorta in tetrapods (the remainder forms the pulmonary artery). A second, dorsal aorta carries oxygenated blood from the gills to the rest of the body, and is homologous with the descending aorta of tetrapods. The two aortas are connected by a number of vessels, one passing through each of the gills. Amphibians also retain the fifth connecting vessel, so that the aorta has two parallel arches" xsd:string [Term] id: UBERON:0000948 name: heart namespace: uberon def: "A myogenic muscular circulatory organ found in the vertebrate cardiovascular system composed of chambers of cardiac muscle. It is the primary circulatory organ." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Heart] comment: Taxon notes:" the ascidian tube-like heart lacks chambers....The ascidian heart is formed after metamorphosis as a simple tube-like structure with a single-layered myoepithelium that is continuous with a single-layered pericar- dial wall. It lacks chambers and endocardium.... The innovation of the chambered heart was a key event in vertebrate evolution, because the chambered heart generates one-way blood flow with high pressure, a critical requirement for the efficient blood supply of large-body vertebrates... all extant vertebrates have hearts with two or more chambers (Moorman and Christoffels 2003)" DOI:10.1101/gad.1485706 subset: efo_slim subset: human_reference_atlas subset: major_organ subset: organ_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "branchial heart" NARROW SENSU [] synonym: "cardium" RELATED [EMAPA:16105] synonym: "chambered heart" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "vertebrate heart" EXACT [] xref: AAO:0010210 xref: BILA:0000020 xref: BTO:0000562 xref: CALOHA:TS-0445 xref: EFO:0000815 xref: EHDAA2:0000738 xref: EHDAA:420 xref: EMAPA:16105 xref: EV:0100018 xref: FMA:7088 xref: GAID:174 xref: galen:Heart xref: MA:0000072 xref: MAT:0000036 xref: MESH:D006321 xref: MIAA:0000036 xref: NCIT:C12727 xref: SCTID:302509004 xref: TAO:0000114 xref: UMLS:C0018787 {source="ncithesaurus:Heart"} xref: VHOG:0000276 xref: Wikipedia:Heart xref: XAO:0000064 xref: ZFA:0000114 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005181 ! thoracic segment organ is_a: UBERON:0007100 ! primary circulatory organ is_a: UBERON:0010314 ! structure with developmental contribution from neural crest intersection_of: UBERON:0007100 ! primary circulatory organ intersection_of: has_part UBERON:0004151 ! cardiac chamber relationship: contributes_to_morphology_of UBERON:0004535 ! cardiovascular system relationship: develops_from UBERON:0004141 ! heart tube relationship: has_part UBERON:0004151 ! cardiac chamber relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0015410 {source="MA"} ! heart plus pericardium property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.0/VH_F_Heart.glb" xsd:anyURI property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Heart.glb" xsd:anyURI property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Heart.glb" xsd:anyURI property_value: RO:0002161 NCBITaxon:6239 property_value: RO:0002161 NCBITaxon:7227 property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Blood pumping organ composed of four chambers: sinus venosus, atrium, cardiac ventricle and bulbus arteriosus.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000114", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "Part of the circulatory system responsible for pumping blood; composed of three chambers--two atria and one ventricle.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010210", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000002 "relationship type change: differentiates_from lateral plate mesoderm (AAO:0010574) CHANGED TO: develops_from lateral plate mesoderm (UBERON:0003081)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010210", ontology="AAO"} property_value: UBPROP:0000003 "As noted, the hearts of birds and mammals have four chambers that arises from the two chambers (atrium and ventricle) of the fish heart.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000276", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.481", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "cardiac" xsd:string [Term] id: UBERON:0000949 name: endocrine system namespace: uberon def: "Anatomical system that consists of the glands and parts of glands that produce endocrine secretions and help to integrate and control bodily metabolic activity." [NLM:endocrine+system, Wikipedia:Endocrine_system] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "endocrine glandular system" EXACT [EHDAA2:0002224] synonym: "endocrine system" EXACT [] synonym: "systema endocrinum" EXACT [] xref: AAO:0010279 xref: CALOHA:TS-1301 xref: EFO:0002969 xref: EHDAA2:0002224 xref: EMAPA:35306 xref: EV:0100128 xref: FBbt:00005068 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:9668 xref: GAID:439 xref: MA:0000012 xref: MESH:D004703 xref: NCIT:C12705 xref: SCTID:278876000 xref: TAO:0001158 xref: UMLS:C0014136 {source="ncithesaurus:Endocrine_System"} xref: VHOG:0000098 xref: Wikipedia:Endocrine_system xref: XAO:0000158 xref: ZFA:0001158 is_a: UBERON:0015204 ! glandular system disjoint_from: UBERON:0000990 ! reproductive system disjoint_from: UBERON:0001004 ! respiratory system disjoint_from: UBERON:0001007 ! digestive system disjoint_from: UBERON:0001009 ! circulatory system disjoint_from: UBERON:0001016 ! nervous system disjoint_from: UBERON:0001434 ! skeletal system disjoint_from: UBERON:0002204 ! musculoskeletal system disjoint_from: UBERON:0002294 ! biliary system disjoint_from: UBERON:0002330 ! exocrine system disjoint_from: UBERON:0002390 ! hematopoietic system disjoint_from: UBERON:0002405 ! immune system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:8450002 ! excretory system relationship: composed_primarily_of UBERON:0002368 ! endocrine gland relationship: existence_ends_during UBERON:0000066 ! fully formed stage relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa property_value: UBPROP:0000001 "Anatomical system containing glands which regulates bodily functions though the secretion of hormones.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010279", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000003 "Multicellular organisms have complex endocrine systems, allowing responses to environmental stimuli, regulation of development, reproduction, and homeostasis. Nuclear receptors (NRs), a metazoan-specific family of ligand-activated transcription factors, play central roles in endocrine responses, as intermediates between signaling molecules and target genes. The NR family includes ligand-bound and orphan receptors, that is, receptors with no known ligand or for which there is no ligand Pocket. Understanding NR evolution has been further improved by comparison of several completed genomes, particularly those of deuterostomes and ecdysozoans. In contrast, evolution of NR ligands is still much debated. One hypothesis proposes that several independent gains and losses of ligand-binding ability in NRs occurred in protostomes and deuterostomes. A second hypothesis, pertaining to the NR3 subfamily (vertebrate steroid hormone receptors and estrogen related receptor), proposes that before the divergence of protostomes and deuterostomes, there was an ancestral steroid receptor (AncSR) that was ligand-activated and that orphan receptors secondarily lost the ability to bind a ligand. (...) Our analysis reveals that steroidogenesis has been independently elaborated in the 3 main bilaterian lineages (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000098", ontology="VHOG", source="DOI:10.1073/pnas.0812138106 Markov GV, Tavares R, Dauphin-Villemant C, Demeneix BA, Baker ME, Laudet V, Independent elaboration of steroid hormone signaling pathways in metazoans. PNAS (2009)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "endocrine" xsd:string [Term] id: UBERON:0000955 name: brain namespace: uberon def: "The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals. Some primitive animals such as jellyfish and starfish have a decentralized nervous system without a brain, while sponges lack any nervous system at all. In vertebrates, the brain is located in the head, protected by the skull and close to the primary sensory apparatus of vision, hearing, balance, taste, and smell[WP]." [https://github.com/obophenotype/uberon/issues/300, Wikipedia:Brain] subset: cumbo subset: efo_slim subset: human_reference_atlas subset: major_organ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "encephalon" RELATED [BTO:0000142] synonym: "suprasegmental levels of nervous system" RELATED [NeuroNames:21] synonym: "suprasegmental structures" RELATED [NeuroNames:21] synonym: "synganglion" RELATED [] synonym: "the brain" RELATED [NeuroNames:21] xref: AAO:0010478 xref: ABA:Brain xref: BAMS:Br xref: BAMS:Brain xref: BILA:0000135 xref: BIRNLEX:796 xref: BTO:0000142 xref: CALOHA:TS-0095 xref: DHBA:10155 xref: EFO:0000302 xref: EHDAA2:0000183 xref: EHDAA:2641 xref: EHDAA:6485 xref: EMAPA:16894 xref: EV:0100164 xref: FBbt:00005095 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:50801 xref: GAID:571 xref: galen:Brain xref: HBA:4005 xref: MA:0000168 xref: MAT:0000098 xref: MBA:8 xref: MBA:997 xref: MESH:D001921 xref: MIAA:0000098 xref: NCIT:C12439 xref: neuronames:21 {source="BIRNLEX:796"} xref: PBA:3999 xref: SCTID:258335003 xref: TAO:0000008 xref: UMLS:C0006104 {source="ncithesaurus:Brain", source="BIRNLEX:796"} xref: UMLS:C1269537 {source="BIRNLEX:796"} xref: VHOG:0000157 xref: Wikipedia:Brain xref: XAO:0000010 xref: ZFA:0000008 is_a: UBERON:0000062 {source="GO"} ! organ is_a: UBERON:0004121 ! ectoderm-derived structure relationship: capable_of GO:0050890 {gci_relation="part_of", gci_filler="NCBITaxon:9606"} ! cognition relationship: composed_primarily_of CL:0002319 ! neural cell relationship: contributes_to_morphology_of UBERON:0001016 ! nervous system relationship: develops_from UBERON:0001049 {gci_relation="part_of", gci_filler="NCBITaxon:7711"} ! neural tube relationship: develops_from UBERON:0006238 ! future brain relationship: existence_ends_during UBERON:0000066 ! fully formed stage relationship: immediate_transformation_of UBERON:0006238 {source="Bgee:AN"} ! future brain relationship: in_anterior_side_of UBERON:0000468 ! multicellular organism relationship: part_of UBERON:0001017 {source="FMA"} ! central nervous system property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/Allen_F_Brain.glb" xsd:anyURI property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/Allen_M_Brain.glb" xsd:anyURI property_value: editor_note "requires review for applicability to invertebrate structures, e.g. synganglion" xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Cavitated compound organ which is comprised of gray and white matter and surrounds the cerebral ventricular system.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000008", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "Part of the central nervous system situated within the cranium and composed of both nerve cell bodies and nerve fibers.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010478", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "The part of the central nervous system contained within the cranium, comprising the forebrain, midbrain, hindbrain, and metencephalon. It is derived from the anterior part of the embryonic neural tube (or the encephalon). Does not include retina. (CUMBO)" xsd:string {source="http://neurolex.org/wiki/Cumbo_terms"} property_value: UBPROP:0000003 "(...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...) (reference 1); The neural tube is destined to differentiate into the brain and spinal cord (the central nervous system) (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000157", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28, ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.165", source="http://bgee.unil.ch/"} property_value: x_1.1:contributor https://github.com/cmungall [Term] id: UBERON:0000957 name: lamina namespace: uberon def: "Any thin layer or plate." [Wikipedia:Lamina_of_the_vertebral_arch] subset: non_informative subset: uberon_slim subset: upper_level synonym: "laminar tissue" EXACT [] xref: Wikipedia:Lamina_of_the_vertebral_arch is_a: UBERON:0000479 ! tissue intersection_of: UBERON:0000479 ! tissue intersection_of: has_quality PATO:0002124 ! laminar relationship: has_quality PATO:0002124 ! laminar property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/8/80/Laminaarcusvertebrae.png" xsd:anyURI property_value: editor_note "TODO - merge with cell layer?" xsd:string property_value: UBPROP:0000007 "laminar" xsd:string [Term] id: UBERON:0000962 name: nerve of cervical vertebra namespace: uberon def: "The cervical nerves are the spinal nerves from the cervical vertebrae. Although there are seven cervical vertebrae (C1-C7), there are eight cervical nerves (C1-C8). All nerves except C8 emerge above their corresponding vertebrae, while the C8 nerve emerges below the C7 vertebra. (In the other portions of the spine, the nerve emerges below the vertebra with the same name. Dorsal (posterior) distribution includes the greater occipital (C2) and third occipital (C3). Ventral (anterior) distribution includes the cervical plexus (C1-C4) and brachial plexus (C5-C8) [WP,unvetted]." [Wikipedia:Cervical_nerves] comment: Innervates: sternohyoid muscle, sternothyroid muscle, omohyoid muscle[WP] subset: uberon_slim synonym: "cervical nerve" EXACT [FMA:5859] synonym: "cervical nerve tree" EXACT [] synonym: "cervical spinal nerve" EXACT [] synonym: "nervus cervicalis" EXACT OMO:0003011 [FMA:5859, FMA:TA] xref: BAMS:cern xref: FMA:5859 xref: NCIT:C32299 xref: neuronames:2351 xref: NLXANAT:20090207 xref: SCTID:360497008 xref: UMLS:C0228815 {source="ncithesaurus:Cervical_Nerve"} xref: Wikipedia:Cervical_nerves is_a: UBERON:0001780 ! spinal nerve intersection_of: UBERON:0001780 ! spinal nerve intersection_of: extends_fibers_into UBERON:0002726 ! cervical spinal cord relationship: extends_fibers_into UBERON:0002726 ! cervical spinal cord property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/e/e6/Gray795.png" xsd:anyURI [Term] id: UBERON:0000963 name: head sensillum namespace: uberon xref: FBbt:00004114 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: MAT:0000204 xref: MIAA:0000204 is_a: UBERON:0002536 ! arthropod sensillum intersection_of: UBERON:0002536 ! arthropod sensillum intersection_of: part_of UBERON:0000033 ! head relationship: part_of UBERON:0000033 ! head property_value: editor_note "this term should be ceded to the arthropod anatomy ontology" xsd:string [Term] id: UBERON:0000964 name: cornea namespace: uberon def: "The transparent anterior portion of the fibrous coat of the eye that serves as the chief refractory structure." [ISBN:0-683-40008-8, MESH:A09.371.060.217, MP:0001312] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "cornea of camera-type eye" EXACT [GO:0061303] synonym: "corneas" RELATED OMO:0003004 [ZFA:0000640] synonym: "tunica cornea" RELATED [] xref: AAO:0010344 xref: BTO:0000286 xref: CALOHA:TS-0171 xref: EFO:0000377 xref: EHDAA2:0000316 xref: EHDAA:10199 xref: EMAPA:17161 xref: EV:0100341 xref: FMA:58238 xref: GAID:892 xref: MA:0000266 xref: MESH:D003315 xref: NCIT:C12342 xref: SCTID:181162001 xref: TAO:0000640 xref: UMLS:C0010031 {source="ncithesaurus:Cornea"} xref: VHOG:0000164 xref: Wikipedia:Cornea xref: XAO:0000180 xref: ZFA:0000640 is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0010000 ! multicellular anatomical structure is_a: UBERON:0010313 ! neural crest-derived structure relationship: continuous_with UBERON:0001773 ! sclera relationship: contributes_to_morphology_of UBERON:0001801 ! anterior segment of eyeball relationship: developmentally_induced_by UBERON:0005426 ! lens vesicle relationship: develops_from UBERON:0004348 {evidence="definitional"} ! optic eminence relationship: develops_from UBERON:0005427 ! corneal primordium relationship: has_part UBERON:0001772 ! corneal epithelium relationship: has_part UBERON:0004370 ! anterior limiting lamina of cornea relationship: has_quality PATO:0000964 ! transparent relationship: part_of UBERON:0001801 {source="MA"} ! anterior segment of eyeball relationship: part_of UBERON:0010409 {source="MA"} ! ocular surface region relationship: part_of UBERON:0012430 {source="FMA-isa"} ! tunica fibrosa of eyeball property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000007 "corneal" xsd:string property_value: UBPROP:0000008 "Compared to terrestial animals, the cornea of zebrafish is relatively flat. It consists of nonpigmented, stratified squamous nonkeratinizing epithelial cells, attached to a thick basement membrane that is considered to be analogous to the Bowman's membrane in mammals. In fish, and aquatic vertebrates in general, the cornea plays no role in focusing light, since it has virtually the same refractive index as water" xsd:string [Term] id: UBERON:0000965 name: lens of camera-type eye namespace: uberon def: "A transparent and refractive lens located posterior to the iris. The lens of camera-type eye refracts light to be focused on the retina." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Lens_(anatomy)] comment: The lens is avascular and nourished by diffusion from the aqueous and vitreous humors. subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "camera-type eye lens" EXACT [GO:0002088] synonym: "crystalline lens" RELATED [BTO:0000723, PMID:36055924] synonym: "eye lens" EXACT SENSU [] synonym: "lens" EXACT SENSU [] synonym: "lens crystallina" EXACT [Wikipedia:Lens_(anatomy)] synonym: "lenses" RELATED OMO:0003004 [ZFA:0000035] synonym: "ocular lens" RELATED [BTO:0000723] xref: AAO:0010348 xref: BTO:0000723 xref: CALOHA:TS-0545 xref: EHDAA:9057 xref: EMAPA:17838 xref: EV:0100343 xref: FMA:58241 xref: MA:0000275 xref: MAT:0000141 xref: MESH:D007908 xref: MIAA:0000141 xref: NCIT:C12743 xref: RETIRED_EHDAA2:0000975 xref: SCTID:181169005 xref: TAO:0000035 xref: UMLS:C0023317 {source="ncithesaurus:Crystalline_Lens"} xref: VHOG:0000169 xref: Wikipedia:Lens_(anatomy) xref: XAO:0000008 xref: ZFA:0000035 is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0005389 ! transparent eye structure relationship: contributes_to_morphology_of UBERON:0001801 ! anterior segment of eyeball relationship: developmentally_induced_by UBERON:0003902 ! retinal neural layer relationship: develops_from UBERON:0005426 ! lens vesicle relationship: part_of UBERON:0001801 ! anterior segment of eyeball property_value: RO:0002171 UBERON:0002049 property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000003 "The eye of the adult lamprey is remarkably similar to our own, and it possesses numerous features (including the expression of opsin genes) that are very similar to those of the eyes of jawed vertebrates. The lamprey's camera-like eye has a lens, an iris and extra-ocular muscles (five of them, unlike the eyes of jawed vertebrates, which have six), although it lacks intra-ocular muscles. Its retina also has a structure very similar to that of the retinas of other vertebrates, with three nuclear layers comprised of the cell bodies of photoreceptors and bipolar, horizontal, amacrine and ganglion cells. The southern hemisphere lamprey, Geotria australis, possesses five morphological classes of retinal photoreceptor and five classes of opsin, each of which is closely related to the opsins of jawed vertebrates. Given these similarities, we reach the inescapable conclusion that the last common ancestor of jawless and jawed vertebrates already possessed an eye that was comparable to that of extant lampreys and gnathostomes. Accordingly, a vertebrate camera-like eye must have been present by the time that lampreys and gnathostomes diverged, around 500 Mya.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000169", ontology="VHOG", source="DOI:10.1038/nrn2283 Lamb TD, Collin SP and Pugh EN Jr, Evolution of the vertebrate eye: opsins, photoreceptors, retina and eye cup. Nature Reviews Neuroscience (2007)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "This class excludes compound eye corneal lenses." xsd:string [Term] id: UBERON:0000966 name: retina namespace: uberon def: "The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates." [Wikipedia:Retina, ZFIN:curator] comment: Currently this class encompasses only verteberate AOs but could in theory also include cephalopod - we may want to make a more specific class for vertebrate retina. note that this class excludes ommatidial retinas, as the retina must be part of an eyeball. Use the parent class photoreceptor array / light-sensitive tissue for arthropods subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "inner layer of eyeball" EXACT [] synonym: "Netzhaut" RELATED [BTO:0001175] synonym: "retina of camera-type eye" EXACT [GO:0060041] synonym: "retinas" RELATED OMO:0003004 [ZFA:0000152] synonym: "tunica interna of eyeball" EXACT [] xref: AAO:0010352 xref: BAMS:R xref: BIRNLEX:1153 xref: BTO:0001175 xref: CALOHA:TS-0865 xref: EFO:0000832 xref: EHDAA2:0001627 xref: EHDAA:4757 xref: EMAPA:17168 xref: EV:0100348 xref: FMA:58301 xref: GAID:755 xref: MA:0000276 xref: MAT:0000142 xref: MBA:304325711 xref: MESH:D012160 xref: MIAA:0000142 xref: NCIT:C12343 xref: neuronames:1862 xref: NIFSTD_RETIRED:birnlex_1156 xref: SCTID:181171005 xref: TAO:0000152 xref: UMLS:C0035298 {source="BIRNLEX:1153", source="ncithesaurus:Retina"} xref: UMLS:C1278894 {source="BIRNLEX:1153"} xref: VHOG:0000229 xref: Wikipedia:Retina xref: XAO:0000009 xref: ZFA:0000152 is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0005388 ! photoreceptor array relationship: develops_from UBERON:0003072 {source="EHDAA2"} ! optic cup relationship: has_part CL:0000573 {source="FMA"} ! retinal cone cell relationship: has_part CL:0000604 {source="FMA"} ! retinal rod cell relationship: has_part CL:0000740 {source="FMA"} ! retinal ganglion cell relationship: part_of UBERON:0001802 ! posterior segment of eyeball relationship: part_of UBERON:0019207 ! chorioretinal region property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/e/ed/Human_eye_cross-sectional_view_grayscale.png" xsd:anyURI property_value: RO:0002161 NCBITaxon:6656 property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "The portion of the eye developing from the optic primordium and including the neural retina and the retinal pigment layer. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000152", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "The eye of the adult lamprey is remarkably similar to our own, and it possesses numerous features (including the expression of opsin genes) that are very similar to those of the eyes of jawed vertebrates. The lamprey's camera-like eye has a lens, an iris and extra-ocular muscles (five of them, unlike the eyes of jawed vertebrates, which have six), although it lacks intra-ocular muscles. Its retina also has a structure very similar to that of the retinas of other vertebrates, with three nuclear layers comprised of the cell bodies of photoreceptors and bipolar, horizontal, amacrine and ganglion cells. The southern hemisphere lamprey, Geotria australis, possesses five morphological classes of retinal photoreceptor and five classes of opsin, each of which is closely related to the opsins of jawed vertebrates. Given these similarities, we reach the inescapable conclusion that the last common ancestor of jawless and jawed vertebrates already possessed an eye that was comparable to that of extant lampreys and gnathostomes. Accordingly, a vertebrate camera-like eye must have been present by the time that lampreys and gnathostomes diverged, around 500 Mya.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000229", ontology="VHOG", source="DOI:10.1038/nrn2283 Lamb TD, Collin SP and Pugh EN Jr, Evolution of the vertebrate eye: opsins, photoreceptors, retina and eye cup. Nature Reviews Neuroscience (2007)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "retinal" xsd:string [Term] id: UBERON:0000970 name: eye namespace: uberon def: "An organ that detects light." [https://orcid.org/0000-0002-6601-2165] subset: efo_slim subset: functional_classification subset: human_reference_atlas subset: major_organ subset: organ_slim subset: uberon_slim synonym: "light-detecting organ" RELATED [] synonym: "visual apparatus" RELATED [EV:0100336] xref: BILA:0000017 xref: BTO:0000439 xref: CALOHA:TS-0309 xref: EFO:0000827 xref: EV:0100336 xref: FBbt:00005162 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: GAID:69 xref: MAT:0000140 xref: MESH:D005123 xref: MIAA:0000140 xref: Wikipedia:Eye is_a: UBERON:0000020 ! sense organ relationship: capable_of GO:0009584 ! detection of visible light relationship: has_part CL:0000149 {source="PMID:21062451"} ! visual pigment cell relationship: has_part CL:0000210 {source="PMID:21062451"} ! photoreceptor cell relationship: part_of UBERON:0002104 ! visual system property_value: curator_notes "This class encompasses a variety of light-detecting structures from different phyla with no implication of homology, from the compound insect eye to the vertebrate camera-type eye (distinct classes are provided for each)" xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000007 "ocular" xsd:string property_value: UBPROP:0000007 "optic" xsd:string property_value: UBPROP:0000010 "Note that whilst this is classified as an organ, it is in fact more of a unit composed of different structures: in Drosophila, it includes the interommatidial bristle as a part; we consider here the vertebrate eye to include the eyeball/eye proper as a part, with the eye having as parts (when present): eyelids, conjuctiva," xsd:string [Term] id: UBERON:0000971 name: ommatidium namespace: uberon def: "The smallest morphological and functional unit of the compound eye that consists of a usually limited and often constant number of rhabdomeric photoreceptor cells, cornea-secreting epithelial cells, and interommatidial pigment cells, and may additionally contain crystalline cone cells." [PMID:21062451] subset: uberon_slim synonym: "omatidia" RELATED OMO:0003004 [] synonym: "omatidium" EXACT [] xref: BTO:0001922 xref: FBbt:00004510 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: HAO:0000666 xref: MAT:0000143 xref: MIAA:0000143 xref: Wikipedia:Ommatidium is_a: UBERON:0000970 {source="PMID:21062451"} ! eye is_a: UBERON:0002536 ! arthropod sensillum relationship: part_of UBERON:0000018 ! compound eye property_value: UBPROP:0000007 "ommatidial" xsd:string [Term] id: UBERON:0000974 name: neck namespace: uberon def: "An organism subdivision that extends from the head to the pectoral girdle, encompassing the cervical vertebral column." [http://orcid.org/0000-0002-6601-2165] subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "collum" RELATED OMO:0003011 [Wikipedia:Neck] synonym: "neck (volume)" RELATED [FMA:7155] xref: AEO:0000108 xref: BTO:0000420 xref: CALOHA:TS-2045 xref: EFO:0000967 xref: EHDAA2:0003108 xref: EMAPA:35587 xref: FMA:7155 xref: GAID:86 xref: galen:Neck xref: MA:0000024 xref: MAT:0000297 xref: MESH:D009333 xref: MIAA:0000297 xref: NCIT:C13063 xref: SCTID:302550007 xref: UMLS:C0027530 {source="ncithesaurus:Neck"} xref: Wikipedia:Neck is_a: UBERON:0000475 ! organism subdivision relationship: anteriorly_connected_to UBERON:0000033 ! head relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0000153 ! anterior region of body relationship: posteriorly_connected_to UBERON:0002100 ! trunk property_value: curator_notes "true necks are considered to be present when the pectoral girdle is separate from the skull - Tiktaalik is the earliest known fish to have a true neck." xsd:string property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/9/99/Female_neck.jpg" xsd:anyURI property_value: RO:0002174 NCBITaxon:32443 {source="ISBN:9780674021839"} property_value: UBPROP:0000007 "cervical" xsd:string [Term] id: UBERON:0000977 name: pleura namespace: uberon def: "The invaginated serous membrane that surrounds the lungs (the visceral portion) and lines the walls of the pleural cavity (parietal portion)." [https://github.com/obophenotype/uberon/issues/1231, ISBN:0-683-40008-8, MP:0010820, UBERON:cjm, Wikipedia:Pulmonary_pleurae] subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "pleura" RELATED [] synonym: "pleural tissue" RELATED [BTO:0001791, NCIT:C12469] synonym: "wall of pleural sac" EXACT [] xref: BTO:0001791 xref: CALOHA:TS-2081 xref: EFO:0001980 xref: EMAPA:16775 xref: EV:0100044 xref: FMA:9583 xref: GAID:360 xref: MA:0000433 xref: MESH:D010994 xref: NCIT:C12469 xref: SCTID:181609007 xref: UMLS:C0032225 {source="ncithesaurus:Pleural_Tissue"} xref: VHOG:0000394 xref: Wikipedia:Pleura is_a: UBERON:0000042 ! serous membrane is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure intersection_of: UBERON:0000042 ! serous membrane intersection_of: has_part UBERON:0002400 ! parietal pleura intersection_of: has_part UBERON:0002401 ! visceral pleura intersection_of: part_of UBERON:0009778 ! pleural sac relationship: contributes_to_morphology_of UBERON:0001004 ! respiratory system relationship: develops_from UBERON:0003081 ! lateral plate mesoderm relationship: has_part UBERON:0002400 ! parietal pleura relationship: has_part UBERON:0002401 ! visceral pleura relationship: has_quality PATO:0001748 ! invaginated relationship: only_in_taxon NCBITaxon:32524 ! Amniota relationship: part_of UBERON:0009778 {source="https://github.com/obophenotype/uberon/issues/86"} ! pleural sac property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/a/ab/Gray965.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:8782 {source="ISBN:978-0030223693", source="https://orcid.org/0000-0003-3308-6245"} property_value: UBPROP:0000001 "The serous membrane that covers the lungs and lines the pleural cavity. [Kaufman_MH_and_Bard_JBL, The_anatomical_basis_of_mouse_development_(1999)_San_Diego:_Academic_Press, p.264][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000394", ontology="VHOG", source="ISBN:0124020607", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "pleural" xsd:string property_value: UBPROP:0000012 "In MA, is_a cavity lining (which we equate to parietal). In FMA, is_a (viscous) serous membrane (which includes mesothelium plus connective tissue). Note the MA structure should probably be associated with the mesothelium of pleura in FMA. JB/EHDAA2 argues the term 'pleura' is best used for the mesothelial lining (thus excluding connective tissue). See https://github.com/obophenotype/uberon/issues/86" xsd:string [Term] id: UBERON:0000982 name: skeletal joint namespace: uberon def: "Anatomical structure that consists of two or more adjacent skeletal structures, which may be interconnected by various types of tissue[VSAO]." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, VSAO:0000101, Wikipedia:Joint] subset: efo_slim subset: organ_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "articular joint" RELATED [BTO:0001686] synonym: "articulation" BROAD [VSAO:0000101] synonym: "joint" BROAD [FMA:7490, VSAO:0000101] synonym: "joints" RELATED OMO:0003004 [ZFA:0001596] xref: AEO:0000182 xref: BTO:0001686 xref: CALOHA:TS-2023 xref: EFO:0000948 xref: EMAPA:35456 xref: FMA:7490 xref: GAID:102 xref: galen:Joint xref: MA:0000319 xref: MAT:0000188 xref: MESH:D007596 xref: MIAA:0000188 xref: NCIT:C13044 xref: RETIRED_EHDAA2:0003182 xref: SCTID:302536002 xref: TAO:0000367 xref: UMLS:C0022417 {source="ncithesaurus:Joint"} xref: VHOG:0001276 xref: VSAO:0000101 xref: Wikipedia:Joint xref: XAO:0000171 xref: ZFA:0001596 is_a: UBERON:0004905 ! articulation union_of: UBERON:0002217 ! synovial joint union_of: UBERON:0011134 ! nonsynovial joint disjoint_from: UBERON:0001474 ! bone element relationship: connects UBERON:0004765 ! skeletal element relationship: contributes_to_morphology_of UBERON:0001434 ! skeletal system property_value: UBPROP:0000001 "Anatomical cluster that consists of two or more adjacent bones or cartilages, which may be interconnected by various types of tissue.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000101", ontology="VSAO", source="PSPUB:0000170"} property_value: UBPROP:0000001 "Anatomical cluster which consists of two or more adjacent bones or cartilages, which may be interconnected by various types of tissue.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000367", ontology="TAO", source="TAO:pem"} [Term] id: UBERON:0000988 name: pons namespace: uberon def: "The part of the central nervous system lying between the medulla oblongata and the midbrain, ventral to the cerebellum." [VHOG:0001176] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "pons cerebri" RELATED OMO:0003011 [NeuroNames:547] synonym: "pons of Varolius" EXACT [] synonym: "pons Varolii" EXACT [ncithesaurus:Pons_Varolii] xref: BAMS:PONS xref: BAMS:Pons xref: BIRNLEX:733 xref: BM:Pons xref: BTO:0001101 xref: CALOHA:TS-0813 xref: DHBA:10661 xref: EFO:0001394 xref: EHDAA2:0004394 xref: EMAPA:17563 xref: EV:0100253 xref: FMA:67943 xref: GAID:578 xref: HBA:9131 xref: MA:0000204 xref: MAT:0000115 xref: MBA:771 xref: MESH:D011149 xref: MIAA:0000115 xref: NCIT:C12511 xref: neuronames:547 {source="BIRNLEX:733"} xref: SCTID:279103004 xref: UMLS:C0032639 {source="BIRNLEX:733", source="ncithesaurus:Pons_Varolii"} xref: UMLS:C1280999 {source="BIRNLEX:733"} xref: VHOG:0001176 xref: Wikipedia:Pons is_a: UBERON:0002616 ! regional part of brain relationship: contributes_to_morphology_of UBERON:0001895 ! metencephalon relationship: contributes_to_morphology_of UBERON:0002298 ! brainstem relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0001895 {source="neuronames"} ! metencephalon relationship: part_of UBERON:0002298 ! brainstem property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/3/36/Gray768.png" xsd:anyURI property_value: editor_note "The pons is not present in zebrafish. In this ontology we currently have some structures which are applicable to zebrafish appearing as parts of the pons. Currently we only include the weaker dubious_for_taxon relationship ubtil this is resolved" xsd:string property_value: RO:0002174 NCBITaxon:7955 property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "The part of the central nervous system lying between the medulla oblongata and the midbrain, ventral to the cerebellum. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001176", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/pons"} property_value: UBPROP:0000003 "During the embryonic development of birds and mammals, neuroblasts migrate from the cerebellum into the ventral part of the rhombencephalon and differentiate into pontine and other nuclei, which relay information from between the cerebrum and cerebellum, and a conspicuous band of transverse fibers. This region is known as the pons. A pons does not differentiate in reptiles and anamniotes (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001176", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.474", source="http://bgee.unil.ch/"} [Term] id: UBERON:0000989 name: penis namespace: uberon def: "An intromittent organ in certain biologically male organisms. In placental mammals, this also serves as the organ of urination." [http://orcid.org/0000-0002-6601-2165, ISBN:0-683-40008-8, MP:0005187, Wikipedia:Penis] subset: efo_slim subset: organ_slim subset: pheno_slim subset: uberon_slim synonym: "penes" RELATED OMO:0003004 [] synonym: "phallus" RELATED [] xref: BTO:0000405 xref: CALOHA:TS-0758 xref: EFO:0000987 xref: EHDAA2:0001433 xref: EHDAA:9380 xref: EMAPA:18682 xref: EMAPA_RETIRED:18996 xref: EV:0100107 xref: FMA:9707 xref: GAID:389 xref: galen:Penis xref: MA:0000408 xref: MAT:0000186 xref: MESH:D010413 xref: MIAA:0000186 xref: NCIT:C12409 xref: SCTID:265793009 xref: UMLS:C0030851 {source="ncithesaurus:Penis"} xref: VHOG:0000727 xref: Wikipedia:Penis is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0008811 {source="Wikipedia"} ! intromittent organ relationship: develops_from UBERON:0004876 {source="Wikipedia"} ! urogenital fold relationship: develops_from UBERON:0005876 {source="EHDAA2"} ! undifferentiated genital tubercle property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/8/87/Labelled_flaccid_penis.jpg" xsd:anyURI property_value: UBPROP:0000007 "penile" xsd:string property_value: UBPROP:0000007 "phallic" xsd:string property_value: UBPROP:0000008 "Most male birds (e.g., roosters and turkeys) have a cloaca (also present on the female), but not a penis. Among bird species with a penis are paleognathes (tinamous and ratites), Anatidae (ducks, geese and swans), and a very few other species (such as flamingoes). A bird penis is different in structure from mammal penises, being an erectile expansion of the cloacal wall and being erected by lymph, not blood. It is usually partially feathered and in some species features spines and brush-like filaments, and in flaccid state curls up inside the cloaca" xsd:string {source="WP"} [Term] id: UBERON:0000990 name: reproductive system namespace: uberon def: "Anatomical system that has as its parts the organs concerned with reproduction." [Wikipedia:Reproductive_system] subset: efo_slim subset: functional_classification subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "animal reproductive system" RELATED [BTO:0000081] synonym: "genital system" NARROW [] synonym: "genital tract" RELATED [] synonym: "genitalia" NARROW OMO:0003004 [] synonym: "Geschlechtsorgan" RELATED [BTO:0000081] synonym: "organa genitalia" RELATED [BTO:0000081] synonym: "reproductive tissue" RELATED [BTO:0000081] synonym: "reproductive tract" RELATED [] synonym: "systemata genitalia" RELATED OMO:0003011 [Wikipedia:Reproductive_system] xref: AAO:0010258 xref: BILA:0000103 xref: BTO:0000081 xref: CALOHA:TS-1318 xref: EFO:0000809 xref: EHDAA2:0001603 xref: EHDAA:5923 xref: EMAPA:17381 xref: EV:0100100 xref: FBbt:00004857 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:7160 xref: GAID:363 xref: HAO:0000374 xref: HAO:0000895 xref: MA:0000326 xref: MESH:D005835 {sssom:mapping_provider="https://github.com/biopragmatics/biomappings", sssom:mapping_justification="vocab:LexicalMatching"} xref: MIAA:0000305 xref: NCIT:C12841 xref: SCTID:278875001 xref: TAO:0000632 xref: UMLS:C1261210 {source="ncithesaurus:Reproductive_System"} xref: VHOG:0000182 xref: WBbt:0005747 xref: Wikipedia:Reproductive_system xref: XAO:0000142 xref: ZFA:0000632 is_a: UBERON:0000467 ! anatomical system intersection_of: UBERON:0000467 ! anatomical system intersection_of: capable_of_part_of GO:0000003 ! reproduction disjoint_from: UBERON:0001004 ! respiratory system disjoint_from: UBERON:0001007 ! digestive system disjoint_from: UBERON:0001009 ! circulatory system disjoint_from: UBERON:0001016 ! nervous system disjoint_from: UBERON:0001434 ! skeletal system disjoint_from: UBERON:0002204 ! musculoskeletal system disjoint_from: UBERON:0002294 ! biliary system disjoint_from: UBERON:0002330 ! exocrine system disjoint_from: UBERON:0002390 ! hematopoietic system disjoint_from: UBERON:0002405 ! immune system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:8450002 ! excretory system relationship: capable_of_part_of GO:0000003 ! reproduction relationship: existence_ends_during UBERON:0000066 ! fully formed stage relationship: has_part UBERON:0000991 ! gonad property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/5/52/Penis.svg" xsd:anyURI property_value: editor_note "consider splitting genitalia from reproductive system" xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: term:date "2022-06-10T18:22:34Z" xsd:dateTime property_value: UBPROP:0000001 "Anatomical system which consists of organs and tissues associated with sexual reproduction of the organism.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010258", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000003 "Arguably, one of the most important aspects of urbilaterian organogenesis would have been gonadogenesis, since Urbilateria must have successfully generated gametes and developed a strategy for extrusion and fertilization, in order to be the ancestor of all living Bilateria.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000182", ontology="VHOG", source="PMID:21672850 Extavour CGM, Gray anatomy: phylogenetic patterns of somatic gonad structures and reproductive strategies across Bilateria. Integrative and Comparative Biology (2007)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000202 FMA:75572 [Term] id: UBERON:0000991 name: gonad namespace: uberon def: "Reproductive organ that produces and releases eggs (ovary) or sperm (testis)." [ISBN:0140512888, Wikipedia:Gonad, ZFA:0000413, ZFIN:curator] subset: major_organ subset: organ_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "gonada" EXACT [] synonym: "gonads" RELATED OMO:0003004 [ZFA:0000413] xref: AAO:0000213 xref: BILA:0000123 xref: BSA:0000079 xref: BTO:0000534 xref: EMAPA:17383 xref: FBbt:00004858 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:18250 xref: GAID:368 xref: HAO:0000379 xref: MA:0002420 xref: MESH:D006066 xref: NCIT:C12725 xref: SCTID:304623008 xref: TAO:0000413 xref: UMLS:C0018067 {source="ncithesaurus:Gonad"} xref: VHOG:0000397 xref: WBbt:0005175 xref: Wikipedia:Gonad xref: XAO:0003146 xref: ZFA:0000413 is_a: UBERON:0003133 ! reproductive organ intersection_of: UBERON:0003133 ! reproductive organ intersection_of: has_part CL:0000586 ! germ cell relationship: contains_process GO:0007276 ! gamete generation relationship: develops_from UBERON:0005564 ! gonad primordium relationship: has_part CL:0000586 ! germ cell property_value: UBPROP:0000001 "Anatomical structure which produces gametes as well as certain sex hormones controlled by the pituitary gonadotropins.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000213", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "The part of the reproductive system that produces and releases eggs (ovary) or sperm (testis).[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000413", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "Examination of different vertebrate species shows that the adult gonad is remarkably similar in its morphology across different phylogenetic classes. Surprisingly, however, the cellular and molecular programs employed to create similar organs are not evolutionarily conserved.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000397", ontology="VHOG", source="DOI:10.1146/annurev.cellbio.042308.13350 DeFalco T, Capel B, Gonad morphogenesis in vertebrates: divergent means to a convergent end. Annual review of cell and developmental biology (2009)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "gonadal" xsd:string property_value: UBPROP:0000012 "FMA xref is a 'general anatomical term'" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0000992 name: ovary namespace: uberon def: "The gonad of a female organism which contains germ cells." [ISBN:0-683-40008-8, MP:0001126, Wikipedia:Ovary] subset: efo_slim subset: human_reference_atlas subset: organ_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "animal ovary" EXACT [EFO:0000973] synonym: "female gonad" EXACT [] synonym: "female organism genitalia gonad" EXACT [OBOL:automatic] synonym: "female organism genitalia gonada" EXACT [OBOL:automatic] synonym: "female organism reproductive system gonad" EXACT [OBOL:automatic] synonym: "female organism reproductive system gonada" EXACT [OBOL:automatic] synonym: "female reproductive system gonad" EXACT [OBOL:automatic] synonym: "female reproductive system gonada" EXACT [OBOL:automatic] synonym: "genitalia of female organism gonad" EXACT [OBOL:automatic] synonym: "genitalia of female organism gonada" EXACT [OBOL:automatic] synonym: "gonad of female organism genitalia" EXACT [OBOL:automatic] synonym: "gonad of female organism reproductive system" EXACT [OBOL:automatic] synonym: "gonad of female reproductive system" EXACT [OBOL:automatic] synonym: "gonad of genitalia of female organism" EXACT [OBOL:automatic] synonym: "gonad of reproductive system of female organism" EXACT [OBOL:automatic] synonym: "gonada of female organism genitalia" EXACT [OBOL:automatic] synonym: "gonada of female organism reproductive system" EXACT [OBOL:automatic] synonym: "gonada of female reproductive system" EXACT [OBOL:automatic] synonym: "gonada of genitalia of female organism" EXACT [OBOL:automatic] synonym: "gonada of reproductive system of female organism" EXACT [OBOL:automatic] synonym: "ovaries" RELATED OMO:0003004 [] synonym: "ovarium" RELATED OMO:0003011 [Wikipedia:Ovary] synonym: "ovum-producing ovary" EXACT SENSU [GO:0061039] synonym: "reproductive system of female organism gonad" EXACT [OBOL:automatic] synonym: "reproductive system of female organism gonada" EXACT [OBOL:automatic] xref: AAO:0000371 xref: BILA:0000125 xref: BSA:0000080 xref: BTO:0000975 xref: CALOHA:TS-0730 xref: EFO:0000973 xref: EHDAA2:0001360 xref: EHDAA:8124 xref: EMAPA:17962 xref: EV:0100111 xref: FBbt:00004865 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:7209 xref: GAID:367 xref: MA:0000384 xref: MESH:D010053 xref: MIAA:0000125 xref: NCIT:C12404 xref: SCTID:181464007 xref: TAO:0000403 xref: UMLS:C0029939 {source="ncithesaurus:Ovary"} xref: VHOG:0000251 xref: Wikipedia:Ovary xref: XAO:0000258 xref: ZFA:0000403 is_a: UBERON:0000991 ! gonad is_a: UBERON:0003134 ! female reproductive organ intersection_of: UBERON:0000991 ! gonad intersection_of: part_of UBERON:0000474 ! female reproductive system disjoint_from: UBERON:0009117 ! indifferent gonad relationship: develops_from UBERON:0009117 ! indifferent gonad relationship: in_lateral_side_of UBERON:0003975 {gci_relation="part_of", gci_filler="NCBITaxon:40674", source="FMA-abduced-lr"} ! internal female genitalia relationship: only_in_taxon NCBITaxon:33208 ! Metazoa property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/d/d4/Gray589.png" xsd:anyURI property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/c/cb/Female_anatomy.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Either of paired female reproductive organs involved in production of ova and female sex hormones.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000371", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "Female reproductive organ.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000403", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "(...) while it is likely that Urbilateria lacked a complex somatic reproductive system, it is at present impossible to speculate on whether or not it possessed a true gonad, let alone any other somatic adaptations for reproduction (reference 1); Examination of different vertebrate species shows that the adult gonad is remarkably similar in its morphology across different phylogenetic classes. Surprisingly, however, the cellular and molecular programs employed to create similar organs are not evolutionarily conserved (reference 2).[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000251", ontology="VHOG", source="DOI:10.1093/icb/icm052 Extavour CGM, Gray anatomy: phylogenetic patterns of somatic gonad structures and reproductive strategies across the Bilateria. Integrative and Comparative Biology (2007), DOI:10.1146/annurev.cellbio.042308.13350 DeFalco T and Capel B, Gonad morphogenesis in vertebrates: divergent means to a convergent end. Annual review of cell and developmental biology (2009)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "ovarian" xsd:string property_value: UBPROP:0000008 "Ovaries of some kind are found in the female reproductive system of many animals that employ sexual reproduction, including invertebrates. However, they develop in a very different way in most invertebrates than they do in vertebrates, and are not truly homologous. Many of the features found in human ovaries are common to all vertebrates, including the presence of follicular cells, tunica albuginea, and so on. However, many species produce a far greater number of eggs during their lifetime than do humans, so that, in fish and amphibians, there may be hundreds, or even millions of fertile eggs present in the ovary at any given time. In these species, fresh eggs may be developing from the germinal epithelium throughout life. Corpora lutea are found only in mammals, and in some elasmobranch fish; in other species, the remnants of the follicle are quickly resorbed by the ovary. In birds, reptiles, and monotremes, the egg is relatively large, filling the follicle, and distorting the shape of the ovary at maturity. Amphibians and reptiles have no ovarian medulla; the central part of the ovary is a hollow, lymph-filled space. The ovary of teleosts is also often hollow, but in this case, the eggs are shed into the cavity, which opens into the oviduct. Although most normal female vertebrates have two ovaries, this is not the case in all species. In birds and platypuses, the right ovary never matures, so that only the left is functional. In some elasmobranchs, the reverse is true, with only the right ovary fully developing. In the primitive jawless fish, and some teleosts, there is only one ovary, formed by the fusion of the paired organs in the embryo" xsd:string {source="WP"} [Term] id: UBERON:0000993 name: oviduct namespace: uberon def: "A tube or collection of tubes in an animal from the ovaries to the outside of the body." [http://orcid.org/0000-0002-6601-2165] subset: efo_slim subset: uberon_slim subset: vertebrate_core synonym: "female reproductive tracts" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "ovarian duct" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "ovarian tube" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "oviducts" RELATED OMO:0003004 [ZFA:0000560] synonym: "tuba uterina" RELATED [BTO:0000980] synonym: "tuba uterinae" RELATED [BTO:0000980] synonym: "tubular parts of female reproductive system" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "uterine tube" EXACT [] xref: AAO:0010533 xref: BSA:0000083 xref: BTO:0000980 xref: EFO:0000974 xref: EMAPA:18984 xref: GAID:366 xref: MAT:0000126 xref: MESH:D010057 xref: MIAA:0000126 xref: NCIT:C77957 xref: TAO:0000560 xref: UMLS:C0029954 {source="ncithesaurus:Oviduct"} xref: VHOG:0001136 xref: Wikipedia:Oviduct xref: XAO:0003052 xref: ZFA:0000560 is_a: UBERON:0000025 ! tube is_a: UBERON:0005156 ! reproductive structure relationship: connects UBERON:0000992 ! ovary relationship: connects UBERON:0013514 ! space surrounding organism relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of UBERON:0000474 ! female reproductive system property_value: curator_notes "sometimes oviduct is used interchangeably with follaopian tube. Here they are different - the oviduct connects the gonad to the outside in a variety of animals. The mammal-class fallopian tube is derived from the mullerian duct and connects the gonads/infubdibulum to the uterus" xsd:string property_value: UBPROP:0000001 "A passage through which ova leave the maternal body or pass to an organ communicating with the exterior of the body. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001136", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/oviduct"} property_value: UBPROP:0000003 "In all remaining vertebrates (i.e., coelacanths, lungfishes, amphibians, reptiles, birds, and mammals), the oviduct arises in ontogeny as a longitudinal, groovelike invagination of the coelomic epithelium on the lateral surface of the mesonephros.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001136", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.687-688", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "in birds divided into infundibulum, magnum, isthmus, uterus, and vagina" xsd:string property_value: UBPROP:0000008 "The only female vertebrates to lack oviducts are the jawless fishes. In these species, the single fused ovary releases eggs directly into the body cavity. The fish eventually extrudes the eggs through small genital pores towards the rear of the body[WP]" xsd:string [Term] id: UBERON:0000995 name: uterus namespace: uberon def: "The female muscular organ of gestation in which the developing embryo or fetus is nourished until birth." [MGI:csmith, MP:0001120] subset: efo_slim subset: human_reference_atlas subset: organ_slim subset: pheno_slim subset: uberon_slim xref: BTO:0001424 xref: CALOHA:TS-1102 xref: EFO:0000975 xref: EMAPA:29915 xref: EV:0100113 xref: FMA:17558 xref: GAID:172 xref: galen:Uterus xref: MA:0000389 xref: MAT:0000127 xref: MESH:D014599 xref: MIAA:0000127 xref: NCIT:C12405 xref: SCTID:181452004 xref: UMLS:C0042149 {source="ncithesaurus:Uterus"} xref: VHOG:0001137 xref: Wikipedia:Uterus is_a: UBERON:0013515 {source="cjm"} ! subdivision of oviduct relationship: develops_from UBERON:0005795 ! embryonic uterus relationship: immediate_transformation_of UBERON:0005795 ! embryonic uterus relationship: only_in_taxon NCBITaxon:32525 ! Theria relationship: part_of UBERON:0004175 ! internal genitalia property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/6/6a/Female_reproductive_system_lateral_nolabel.png" xsd:anyURI property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Uterus.glb" xsd:anyURI property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/c/cb/Female_anatomy.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "The hollow muscular organ in female mammals in which the blastocyst normally becomes embedded and in which the developing embryo and fetus is nourished. Its cavity opens into the vagina below and into a uterine tube on either side. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001137", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/uterus"} property_value: UBPROP:0000003 "An infundibulum, uterine tube, uterus, and vagina also differentiate along the oviducts of eutherian mammals.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001137", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.678", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "uterine" xsd:string property_value: UBPROP:0000008 "Most animals that lay eggs, such as birds and reptiles, have an oviduct instead of a uterus. In monotremes, mammals which lay eggs and include the platypus, either the term uterus or oviduct is used to describe the same organ, but the egg does not develop a placenta within the mother and thus does not receive further nourishment after formation and fertilization. Marsupials have two uteruses, each of which connect to a lateral vagina and which both use a third, middle 'vagina' which functions as the birth canal. Marsupial embryos form a choriovitelline 'placenta' (which can be thought of as something between a monotreme egg and a 'true' placenta), in which the egg's yolk sac supplies a large part of the embryo's nutrition but also attaches to the uterine wall and takes nutrients from the mother's bloodstream." xsd:string property_value: UBPROP:0000011 "Two uteruses usually form initially in a female fetus, and in placental mammals they may partially or completely fuse into a single uterus depending on the species. In many species with two uteruses, only one is functional. Humans and other higher primates such as chimpanzees, along with horses, usually have a single completely fused uterus, although in some individuals the uteruses may not have completely fused [Wikipedia:Uterus]" xsd:string [Term] id: UBERON:0000997 name: mammalian vulva namespace: uberon def: "External genital organs of the female mammal[WP]." [Wikipedia:Vulva] subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "female pudendum" EXACT DEPRECATED [BTO:0003101, doi:10.1002/ca.23705, FMA:20462] synonym: "mammalian vulva" EXACT [] synonym: "puboperineal region" EXACT [FMA:20462] synonym: "pudendum" RELATED DEPRECATED [BTO:0003101, doi:10.1002/ca.23705] synonym: "pudendum femininum" EXACT DEPRECATED [doi:10.1002/ca.23705, FMA:20462, FMA:TA] synonym: "pudendum femininum" RELATED DEPRECATED [doi:10.1002/ca.23705, Wikipedia:Vulva] synonym: "pudendum muliebre" RELATED DEPRECATED [BTO:0003101, doi:10.1002/ca.23705] synonym: "vulva" EXACT [MA:0000395] xref: BTO:0003101 xref: CALOHA:TS-1168 xref: EFO:0000978 xref: EMAPA:36631 xref: EV:0100118 xref: FMA:20462 xref: GAID:383 xref: galen:Vulva xref: MA:0000395 xref: MAT:0000169 xref: MESH:D014844 xref: MIAA:0000169 xref: NCIT:C12408 xref: SCTID:265796001 xref: UMLS:C0042993 {source="ncithesaurus:Vulva"} xref: VHOG:0001458 xref: Wikipedia:Vulva is_a: UBERON:0000062 ! organ is_a: UBERON:0005156 ! reproductive structure relationship: only_in_taxon NCBITaxon:40674 ! Mammalia relationship: part_of UBERON:0005056 ! external female genitalia property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/d/da/Female_unshaved_genitalia.jpg" xsd:anyURI property_value: UBPROP:0000001 "The external genital organs of the female, including the labia majora, labia minora, clitoris, and vestibule of the vagina. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001458", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/vulva"} property_value: UBPROP:0000007 "vulval" xsd:string [Term] id: UBERON:0000998 name: seminal vesicle namespace: uberon def: "Either of a pair of glandular pouches that lie one on either side of the male reproductive tract posterolateral to the urinary bladder and in the human male secrete a sugar- and protein-containing fluid into the ejaculatory duct." [BTO:0001234, Wikipedia:Seminal_vesicle] subset: efo_slim subset: organ_slim subset: pheno_slim subset: uberon_slim synonym: "glandula seminalis" RELATED [BTO:0001234] synonym: "glandula vesiculosa" RELATED [BTO:0001234] synonym: "gonecyst" RELATED [] synonym: "seminal gland" BROAD [] synonym: "vas efferens" RELATED [] synonym: "vesicula seminalis" RELATED [BTO:0001234, Wikipedia:Seminal_vesicle] synonym: "vesiculae seminales" RELATED OMO:0003011 [Wikipedia:Seminal_vesicle] synonym: "vesicular gland" RELATED [Wikipedia:Seminal_vesicle] synonym: "vesicular glands" RELATED [Wikipedia:Seminal_vesicle] synonym: "vesicular seminalis" RELATED [Wikipedia:Seminal_vesicle] synonym: "vesiculæ seminales" RELATED [Wikipedia:Seminal_vesicle] xref: AAO:0010788 xref: BTO:0001234 xref: CALOHA:TS-0919 xref: EFO:0000986 xref: EMAPA:19180 xref: EV:0100106 xref: FMA:19386 xref: GAID:394 xref: MA:0000410 xref: MAT:0000171 xref: MESH:D012669 xref: MIAA:0000171 xref: NCIT:C12787 xref: SCTID:181434004 xref: UMLS:C0036628 {source="ncithesaurus:Seminal_Vesicle"} xref: VHOG:0001379 xref: Wikipedia:Seminal_vesicle is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0006868 ! seminal fluid secreting gland relationship: contributes_to_morphology_of UBERON:0004054 ! internal male genitalia relationship: develops_from UBERON:0000080 ! mesonephros relationship: part_of UBERON:0000473 ! testis relationship: produces UBERON:0010143 ! seminal vesicle fluid property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/d/d1/Male_anatomy_en.svg" xsd:anyURI property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Prostate.glb" xsd:anyURI property_value: UBPROP:0000001 "Either of a pair of pouchlike glands situated on each side of the male urinary bladder that secrete seminal fluid and nourish and promote the movement of spermatozoa through the urethra. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001379", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/prominence"} property_value: UBPROP:0000003 "(In mammalian testis) Along the way (the sperm travel), three accessory sex glands, the seminal vesicle, prostate, and bulbourethral (Cowper's) gland, respectively, add their secretions as sperm move from the testes to the urethra.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001379", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.556", source="http://bgee.unil.ch/"} property_value: UBPROP:0000009 "The seminal vesicles secrete a significant proportion of the fluid that ultimately becomes semen. Lipofuscin granules from dead epithelial cells give the secretion its yellowish color. About 50-70% of the seminal fluid in humans originates from the seminal vesicles, but is not expelled in the first ejaculate fractions which are dominated by spermatozoa and zinc-rich prostatic fluid." xsd:string [Term] id: UBERON:0000999 name: ejaculatory duct namespace: uberon def: "The Ejaculatory ducts (ductus ejaculatorii) are paired structures in male anatomy, about 2 cm in length. Each ejaculatory duct is formed by the union of the vas deferens with the duct of the seminal vesicle. They pass through the prostate, and empty into the urethra at the Colliculus seminalis. During ejaculation, semen passes through the ducts and exits the body via the penis[WP,unvetted]." [Wikipedia:Ejaculatory_duct] subset: efo_slim subset: uberon_slim synonym: "ductus ejaculatorii" EXACT OMO:0003004 [BTO:0001580] synonym: "ductus ejaculatorii" RELATED OMO:0003011 [Wikipedia:Ejaculatory_duct] synonym: "ductus ejaculatorius" EXACT [BTO:0001580] xref: BTO:0001580 xref: CALOHA:TS-0211 xref: EFO:0000985 xref: EMAPA:19088 xref: FMA:19325 xref: GAID:388 xref: MA:0003247 xref: MAT:0000170 xref: MESH:D004543 xref: MIAA:0000170 xref: NCIT:C32493 xref: SCTID:279665005 xref: UMLS:C0013747 {source="ncithesaurus:Ejaculatory_Duct"} xref: Wikipedia:Ejaculatory_duct is_a: UBERON:0000025 ! tube is_a: UBERON:0005904 ! duct of male reproductive system is_a: UBERON:0015212 ! lateral structure relationship: capable_of_part_of GO:0042713 ! sperm ejaculation relationship: channel_for UBERON:0001968 ! semen relationship: channel_for UBERON:0010143 ! seminal vesicle fluid relationship: channels_from UBERON:0000998 ! seminal vesicle relationship: channels_from UBERON:0001000 ! vas deferens relationship: channels_into UBERON:0000057 ! urethra relationship: in_lateral_side_of UBERON:0000079 ! male reproductive system relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Prostate.glb" xsd:anyURI property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/3/35/Male_anatomy.png" xsd:anyURI [Term] id: UBERON:0001000 name: vas deferens namespace: uberon def: "A secretory duct that transports sperm from the testis. In mammals this is a continuation of the epididymis and ends in the prostatic urethra where it terminates to form ejaculatory duct." [http://orcid.org/0000-0002-6601-2165, ISBN:0-683-40008-8, MGI:pvb, MP:0002769, Wikipedia:Vas_deferens] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "deferent duct" EXACT [] synonym: "ductus deferens" EXACT [Wikipedia:Vas_deferens] synonym: "sperm duct" RELATED [] synonym: "vas deferen" EXACT [] synonym: "vasa deferentia" RELATED [] xref: BTO:0001427 xref: CALOHA:TS-1105 xref: EFO:0000981 xref: EMAPA:18681 xref: EV:0100105 xref: FMA:19234 xref: GAID:404 xref: galen:VasDeferens xref: MA:0000413 xref: MESH:D014649 xref: MIAA:0000129 xref: NCIT:C12813 xref: SCTID:245467009 xref: UMLS:C0042360 {source="ncithesaurus:Vas_Deferens"} xref: VHOG:0001135 xref: Wikipedia:Vas_deferens is_a: UBERON:0000025 ! tube is_a: UBERON:0005904 ! duct of male reproductive system relationship: channel_for UBERON:0001968 ! semen relationship: channels_from UBERON:0001301 ! epididymis relationship: channels_into UBERON:0000999 ! ejaculatory duct relationship: contributes_to_morphology_of UBERON:0004054 ! internal male genitalia relationship: only_in_taxon NCBITaxon:32524 ! Amniota relationship: part_of UBERON:0005352 {source="FMA"} ! spermatic cord relationship: part_of UBERON:0006947 ! male genital duct property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/d/d1/Male_anatomy_en.svg" xsd:anyURI property_value: UBPROP:0000003 "The continuation of the archinephric duct, now called the deferent duct, extends caudally to the cloaca or to the part of the mammalian urethra that is derived from the cloaca.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001135", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.670", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "Most vertebrates have some form of duct to transfer the sperm from the testes to the urethra. In cartilaginous fish and amphibians, sperm is carried through the archinephric duct, which also partially helps to transport urine from the kidneys. In teleosts, there is a distinct sperm duct, separate from the ureters, and often called the vas deferens, although probably not truly homologous with that in humans. In cartilaginous fishes, the part of the archinephric duct closest to the testis is coiled up to form an epididymis. Below this are a number of small glands secreting components of the seminal fluid. The final portion of the duct also receives ducts from the kidneys in most species. In amniotes, however, the archinephric duct has become a true vas deferens, and is used only for conducting sperm, never urine. As in cartilaginous fish, the upper part of the duct forms the epididymis. In many species, the vas deferens ends in a small sac for storing sperm. The only vertebrates to lack any structure resembling a vas deferens are the primitive jawless fishes, which release sperm directly into the body cavity, and then into the surrounding water through a simple opening in the body wall." xsd:string {source="WP"} [Term] id: UBERON:0001001 name: chitin-based cuticle namespace: uberon def: "A cuticular covering that is composed primarily of chitin. The main structural component of arthropod cuticle is a polysaccharide, chitin, composed of N-acetylglucosamine units, together with proteins and lipids[WP]." [https://orcid.org/0000-0002-6601-2165, https://sourceforge.net/tracker/index.php?func=detail&aid=3348965&group_id=36855&atid=440764, Wikipedia:Arthropod_exoskeleton, Wikipedia:Cuticle#Invertebrate_zoology] comment: EDITOR_NOTE TODO - split from exoskeleton? Also: See above sf item to see if this belongs in GO subset: efo_slim subset: uberon_slim synonym: "arthropod cuticle" RELATED [] synonym: "arthropod exoskeleton" RELATED [Wikipedia:Arthropod_exoskeleton] synonym: "cuticle" NARROW [FBbt:00004970] synonym: "exoskeleton" BROAD [] synonym: "insect cuticle" RELATED [] xref: EFO:0000944 xref: FBbt:00004970 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: HAO:0000240 xref: MAT:0000150 xref: MIAA:0000150 xref: Wikipedia:Arthropod_exoskeleton is_a: UBERON:0001002 ! cuticle is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0007491 ! chitin-based acellular structure intersection_of: UBERON:0001002 ! cuticle intersection_of: composed_primarily_of CHEBI:17029 ! chitin relationship: develops_from UBERON:0007376 ! outer epithelium relationship: only_in_taxon NCBITaxon:6656 ! Arthropoda relationship: part_of UBERON:0002416 ! integumental system [Term] id: UBERON:0001002 name: cuticle namespace: uberon def: "Tough but flexible, non-mineral outer coverings of an organism, or parts of an organism, that provide protection. Cuticles are non-homologous, differing in their origin, structure and chemical composition[WP]." [http://sourceforge.net/tracker/?func=detail&aid=3348965&group_id=36855&atid=440764, Wikipedia:Cuticle] comment: EDITOR_NOTE TODO - check cuticle vs exoskeleton. Note that GO has a very generic definition of cuticle. See also arthropod-anatomy ontology. Note in ncit Cuticle is a plant part subset: grouping_class subset: non_informative subset: uberon_slim synonym: "cuticula" RELATED [BTO:0001600] synonym: "cuticular exoskeleton" RELATED [] xref: BTO:0001600 xref: Wikipedia:Cuticle is_a: UBERON:0000476 ! acellular anatomical structure relationship: only_in_taxon NCBITaxon:6072 {source="Rieger - Evolution of the Cuticle in the Lower Eumetazoa"} ! Eumetazoa property_value: UBPROP:0000007 "cuticular" xsd:string [Term] id: UBERON:0001003 name: skin epidermis namespace: uberon def: "The outer epithelial layer of the skin that is superficial to the dermis." [http://orcid.org/0000-0002-6601-2165, ISBN:0073040584] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "epidermis" BROAD [] synonym: "skin" BROAD [] synonym: "vertebrate epidermis" EXACT [] xref: AAO:0000143 xref: BTO:0000404 xref: CALOHA:TS-0283 xref: EFO:0000954 xref: EMAPA:17528 xref: EV:0100153 xref: FMA:70596 xref: GAID:932 xref: MA:0000153 xref: MAT:0000154 xref: MESH:D004817 xref: MIAA:0000154 xref: NCIT:C12708 xref: SCTID:361694003 xref: TAO:0000105 xref: UMLS:C0014520 {source="ncithesaurus:Epidermis"} xref: VHOG:0000077 xref: Wikipedia:Epidermis_(skin) xref: XAO:0000028 xref: ZFA:0000105 is_a: UBERON:0007376 ! outer epithelium is_a: UBERON:3000961 ! external integument structure intersection_of: UBERON:0007376 ! outer epithelium intersection_of: part_of UBERON:0002097 ! skin of body relationship: adjacent_to UBERON:0002067 ! dermis relationship: developmentally_replaces UBERON:0003055 ! periderm relationship: part_of UBERON:0002097 ! skin of body property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "A cellular, multilayered epithelium derived from the ectoderm. Zebrafish epidermis consists only of living cells unlike terrestrial vertebrates in which dead, keratinized cells are present. Le Guellec et al, 2004.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000105", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "The outer epithelial layer of the external integument of the body that is derived from the embryonic epiblast.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000143", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000002 "relationship loss: subclass external integument structures (AAO:0000961)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000143", ontology="AAO"} property_value: UBPROP:0000003 "(...) outer epithelia in all metazoan animals are homologous. (...) The ancestor of all metazoans likely had an epidermis with a basal extracellular matrix (ECM), an apical extracellular glycocalyx, and one cilium with a striated rootlet per cell.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000077", ontology="VHOG", source="ISBN:978-0198566694 Schmidt-Rhaesa A, The evolution of organ systems (2007) p.71-72", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "epidermal" xsd:string property_value: UBPROP:0000008 "Zebrafish epidermis consists only of living cells unlike terrestrial vertebrates in which dead, keratinized cells are present. In terrestrial vertebrates the epidermis often forms an outer keratinized or cornified layer, the stratum corneum. Interaction between the epideris and dermis gives rise to feathers (birds), hair and mammary glands (mammals), teeth and scales (placoid: chondrichthyans; cosmoids, ganoid, cycloid in bony fishes)." xsd:string [Term] id: UBERON:0001004 name: respiratory system namespace: uberon def: "Functional system which consists of structures involved in respiration." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Respiratory_system] subset: efo_slim subset: functional_classification subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "apparatus respiratorius" EXACT [] synonym: "apparatus respiratorius" RELATED [BTO:0000203] synonym: "Atmungssystem" RELATED [BTO:0000203] synonym: "respiratory system" EXACT [] synonym: "systema respiratorium" RELATED OMO:0003011 [Wikipedia:Respiratory_system] xref: AAO:0000541 xref: BTO:0000203 xref: CALOHA:TS-1319 xref: EFO:0000804 xref: EHDAA2:0001604 xref: EHDAA:2203 xref: EMAPA:16727 xref: EV:0100036 xref: FMA:7158 xref: GAID:78 xref: MA:0000327 xref: MAT:0000030 xref: MESH:D012137 xref: MIAA:0000030 xref: NCIT:C12779 xref: SCTID:278197002 xref: TAO:0000272 xref: UMLS:C0035237 {source="ncithesaurus:Respiratory_System"} xref: VHOG:0000202 xref: Wikipedia:Respiratory_system xref: XAO:0000117 xref: ZFA:0000272 is_a: UBERON:0000467 ! anatomical system intersection_of: UBERON:0000467 ! anatomical system intersection_of: capable_of GO:0007585 ! respiratory gaseous exchange by respiratory system disjoint_from: UBERON:0001007 ! digestive system disjoint_from: UBERON:0001009 ! circulatory system disjoint_from: UBERON:0001016 ! nervous system disjoint_from: UBERON:0001434 ! skeletal system disjoint_from: UBERON:0002204 ! musculoskeletal system disjoint_from: UBERON:0002294 ! biliary system disjoint_from: UBERON:0002330 ! exocrine system disjoint_from: UBERON:0002390 ! hematopoietic system disjoint_from: UBERON:0002405 ! immune system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:8450002 ! excretory system relationship: capable_of GO:0003016 ! respiratory system process relationship: capable_of GO:0007585 ! respiratory gaseous exchange by respiratory system relationship: existence_ends_during UBERON:0000066 ! fully formed stage relationship: only_in_taxon NCBITaxon:33213 ! Bilateria property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/5/5e/Respiratory_system_complete_en.svg" xsd:anyURI property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.0/VH_F_Lung.glb" xsd:anyURI property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Lung.glb" xsd:anyURI property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Lung.glb" xsd:anyURI property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.4/3d-vh-f-lung.glb" xsd:anyURI property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.4/3d-vh-m-lung.glb" xsd:anyURI property_value: RO:0002161 NCBITaxon:147099 {source="Wikipedia:Acoelomorpha"} property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "The anatomical system in which the exchange of oxygen and carbon dioxide between the organism and its environment.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000541", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000003 "There is no doubt that the primitive pattern of vertebrate air-breathing is the buccal pulse pump found in actinopterygian fishes.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000202", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.599 and Figure 18-23", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001005 name: respiratory airway namespace: uberon def: "An airway through which respiratory air passes in organisms." [Wikipedia:Trachea] subset: grouping_class subset: uberon_slim synonym: "airway" BROAD [http://orcid.org/0000-0002-6601-2165] synonym: "airways" BROAD OMO:0003004 [http://orcid.org/0000-0002-6601-2165] xref: FMA:265130 xref: SCTID:361380005 xref: Wikipedia:Trachea is_a: UBERON:0003103 ! compound organ is_a: UBERON:0004111 ! anatomical conduit relationship: channel_for UBERON:0034874 ! air in respiratory system relationship: part_of UBERON:0001004 ! respiratory system property_value: curator_notes "This class generically groups trachea and analagous structures throughout metazoa. Consider renaming, as the term could be taken to mean lumen of tracheal system (e.g. in SNOMED). As a grouping class this is quite vague, as it is not clear where the airway begins and ends" xsd:string [Term] id: UBERON:0001007 name: digestive system namespace: uberon def: "Anatomical system that has as its parts the organs devoted to the ingestion, digestion, and assimilation of food and the discharge of residual wastes." [FB:gg, NLM:alimentary+system, Wikipedia:Digestive_system] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "alimentary system" RELATED [] synonym: "alimentary tract" RELATED [] synonym: "gastrointestinal system" RELATED [] synonym: "gut" RELATED [] xref: AAO:0000129 xref: BILA:0000082 xref: BTO:0000058 xref: CALOHA:TS-1293 xref: EFO:0000793 xref: EV:0100056 xref: FBbt:00005055 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:7152 xref: GAID:278 xref: galen:DigestiveSystem xref: MA:0002431 xref: MAT:0000018 xref: MESH:D004064 xref: MIAA:0000018 xref: ncithesaurus:Digestive_System xref: SCTID:278859004 xref: TADS:0000170 xref: TAO:0000339 xref: WBbt:0005748 xref: Wikipedia:Digestive_system xref: XAO:0000125 xref: ZFA:0000339 is_a: UBERON:0000467 ! anatomical system intersection_of: UBERON:0000467 ! anatomical system intersection_of: capable_of GO:0022600 ! digestive system process disjoint_from: UBERON:0001009 ! circulatory system disjoint_from: UBERON:0001016 ! nervous system disjoint_from: UBERON:0001434 ! skeletal system disjoint_from: UBERON:0002204 ! musculoskeletal system disjoint_from: UBERON:0002294 ! biliary system disjoint_from: UBERON:0002330 ! exocrine system disjoint_from: UBERON:0002390 ! hematopoietic system disjoint_from: UBERON:0002405 ! immune system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:8450002 ! excretory system relationship: capable_of GO:0022600 ! digestive system process relationship: existence_ends_during UBERON:0000066 ! fully formed stage property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "An anatomical system consisting of the alimentary canal and digestive glands responsible for intake, absorption, digestion and excretion of food.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000129", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000007 "digestive" xsd:string property_value: UBPROP:0000012 "many anatomy ontologies consider gastrointestinal system synonymous with digestive system. here we follow MA in dividing digestive system into gastrointestinal and hepatobiliary. hepatobiliary includes the liver and biliary tract. species-specific AO classes are categorized according to whether liver is included. For example, XAO includes liver as part of XAO:0000125 alimentary system, so we assume this class is the more generic class" xsd:string {external_ontology="MA"} [Term] id: UBERON:0001008 name: renal system namespace: uberon def: "The renal system in an anatomical system that maintains fluid balance and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products." [DOI:10.1371/journal.pone.0099864, GO:0072001] comment: EDITOR_NOTE In various sources such as Encyclopedia Britannica, the excretory and urinary systems are indeed the same system (see wikipedia talk page); we merge two BTO classes here subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "excretory system" BROAD [] synonym: "renal or urinary system" RELATED [EHDAA:5901] synonym: "renal/urinary system" RELATED [] synonym: "systema urinaria" EXACT [FMA:7159] synonym: "systema urinarium" EXACT [BTO:0003092] synonym: "urinary system" EXACT [] synonym: "urinary tract" EXACT [] xref: AAO:0010257 xref: BILA:0000015 xref: BTO:0001244 xref: BTO:0003092 xref: CALOHA:TS-1323 xref: EFO:0000803 xref: EHDAA2:0001601 xref: EHDAA:5901 xref: EMAPA:17366 xref: EV:0100095 xref: FBbt:00005056 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:7159 xref: GAID:391 xref: galen:UrinaryTract xref: MA:0000325 xref: MAT:0000027 xref: MESH:D014551 xref: MIAA:0000027 xref: NCIT:C12413 xref: SCTID:362204003 xref: TADS:0000162 xref: TAO:0000163 xref: UMLS:C1508753 {source="ncithesaurus:Urinary_System"} xref: VHOG:0000723 xref: WBbt:0005736 xref: Wikipedia:Excretory_system xref: XAO:0000143 xref: ZFA:0000163 is_a: UBERON:8450002 ! excretory system intersection_of: UBERON:8450002 ! excretory system intersection_of: capable_of GO:0097254 ! renal tubular secretion relationship: capable_of GO:0097254 ! renal tubular secretion relationship: existence_ends_during UBERON:0000066 ! fully formed stage relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa property_value: RO:0002161 NCBITaxon:110815 {source="Wikipedia"} property_value: RO:0002161 NCBITaxon:147099 {source="Wikipedia:Acoelomorpha"} property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "An anatomical system which consists of organs and tissues which produce, store, and excrete urine.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010257", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000003 "Evolution of vertebrate renal anatomy appears quite conservative when compared, for example, to evolution of respiratory and cardiovascular systems in vertebrates. Major anatomical changes in vertebrates kidneys separate those of birds and mammals from kidneys of lower vertebrates. General increase in animal size from fish to mammals is reflected by an increase in total number of nephrons per kidney, rather than by constant change in tubular dimensions.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000723", ontology="VHOG", source="ISBN:978-3540428541 Kapoor BG, Bhavna Khanna, Ichthyology Handbook (2004) p.406", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels" xsd:string {source="GO"} property_value: UBPROP:0000008 "This definition is inclusive of the organs of the vertebrate renal system, as well as the Malpighian tubules of insects, and allows for future incorporation of structures such as the antennal glands of crustaceans" xsd:string {source="DOI:10.1371/journal.pone.0099864"} [Term] id: UBERON:0001009 name: circulatory system namespace: uberon def: "Organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis[WP]." [Wikipedia:Circulatory_system] subset: human_reference_atlas subset: uberon_slim synonym: "systema cardiovasculare" RELATED OMO:0003011 [Wikipedia:Circulatory_system] xref: AAO:0000959 xref: CALOHA:TS-2103 xref: MESH:D002319 {sssom:mapping_provider="https://github.com/biopragmatics/biomappings", sssom:mapping_justification="vocab:LexicalMatching"} xref: VHOG:0001248 xref: Wikipedia:Circulatory_system is_a: UBERON:0000467 ! anatomical system disjoint_from: UBERON:0001016 ! nervous system disjoint_from: UBERON:0001434 ! skeletal system disjoint_from: UBERON:0002204 ! musculoskeletal system disjoint_from: UBERON:0002294 ! biliary system disjoint_from: UBERON:0002330 ! exocrine system disjoint_from: UBERON:0002390 ! hematopoietic system disjoint_from: UBERON:0002405 ! immune system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:8450002 ! excretory system relationship: capable_of GO:0003013 ! circulatory system process relationship: existence_ends_during UBERON:0000066 ! fully formed stage relationship: only_in_taxon NCBITaxon:33213 ! Bilateria property_value: curator_notes "the cardiovascular system and the lymphatic system are parts of the circulatory system" xsd:string property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/2/29/Circulatory_System_en.svg" xsd:anyURI property_value: RO:0002161 NCBITaxon:147099 {source="Wikipedia:Acoelomorpha"} property_value: RO:0002161 NCBITaxon:6073 property_value: RO:0002161 NCBITaxon:6157 property_value: RO:0002174 NCBITaxon:6231 {notes="WBbt coelomocyte currently classified as circulating cell"} property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Anatomical system of ion binding, a pumping mechanism, and an efficient vascular system; consisting of the blood, heart, and blood and lymph vessels, respectively.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000959", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000003 "We should divest ourselves of the view that earlier vertebrate groups were 'on their way' to becoming mammals, as clearly they were not such visionaries. Neither were their systems 'imperfect' as earlier anatomists thought. Instead, their circulatory systems served them well to address the ecological demands arising from their lifestyles.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001248", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.493", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001013 name: adipose tissue namespace: uberon def: "Portion of connective tissue composed of adipocytes enmeshed in areolar tissue." [http://orcid.org/0000-0002-6601-2165, MESH:A10.165.114, MGI:cwg, MP:0000003, Wikipedia:Adipose_tissue] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "adipose" RELATED [BTO:0001487] synonym: "bodyfat" RELATED [BTO:0001487] synonym: "fat" EXACT [MA:0000009] synonym: "fat tissue" EXACT [] synonym: "fatty depot" RELATED [] synonym: "fatty tissue" EXACT [] xref: AAO:0000001 xref: AEO:000020 xref: BTO:0001487 xref: CALOHA:TS-0013 xref: EFO:0000790 xref: EHDAA2:0003120 xref: EMAPA:35112 xref: EV:0100381 xref: FMA:20110 xref: GAID:920 xref: galen:FattyTissue xref: MA:0000009 xref: MAT:0000015 xref: MESH:D000273 xref: MIAA:0000015 xref: NCIT:C12472 xref: SCTID:55603005 xref: TAO:0002134 xref: UMLS:C0001527 {source="ncithesaurus:Adipose_Tissue"} xref: VHOG:0001284 xref: Wikipedia:Adipose_tissue xref: XAO:0003049 xref: ZFA:0005345 is_a: UBERON:0011822 {source="FMA"} ! dense irregular connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: composed_primarily_of CL:0000136 ! adipocyte disjoint_from: UBERON:0003714 ! neural tissue relationship: composed_primarily_of CL:0000136 ! adipocyte property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Connective tissue in which fat is stored.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002134", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "Tissue that contains adipocytes, used for cushioning, thermal insulation, lubrication (primarily in the pericardium) and energy storage.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000001", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000002 "relationship loss: subclass connective tissue proper (AAO:0000099)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000001", ontology="AAO"} property_value: UBPROP:0000003 "Adipose tissue is unique to vertebrates. It is found in mostmammals, birds, reptiles and amphibians, and a variety is found in some species of fish. Furthermore, in insects the fat body found in larvae as well as in adults shares some homology with adipose tissue.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001284", ontology="VHOG", source="DOI:10.1017/S0029665107005423 Haugen F, Drevon CA, The interplay between nutrients and the adipose tissue. The Proceedings of the Nutrition Society (2007)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "adipose" xsd:string property_value: UBPROP:0000008 "In humans, adipose tissue is located beneath the skin (subcutaneous fat), around internal organs (visceral fat), in bone marrow (yellow bone marrow) and in breast tissue. Adipose tissue is found in specific locations, which are referred to as adipose depots. Adipose tissue contains several cell types, with the highest percentage of cells being adipocytes, which contain fat droplets. Other cell types include fibroblasts, macrophages, and endothelial cells. Adipose tissue contains many small blood vessels.; Mice have eight major adipose depots, four of which are within the abdominal cavity. The paired gonadal depots are attached to the uterus and ovaries in females and the epididymis and testes in males; the paired retroperitoneal depots are found along the dorsal wall of the abdomen, surrounding the kidney, and, when massive, extend into the pelvis. The mesenteric depot forms a glue-like web that supports the intestines, and the omental depot, which originates near the stomach and spleen, and, when massive, extends into the ventral abdomen." xsd:string property_value: UBPROP:0000012 "in FMA this is dense irregular connective tissue" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0001015 name: musculature namespace: uberon def: "A subdivision of the muscular system corresponding to a subdisivision of an organism." [https://orcid.org/0000-0002-6601-2165, Wikipedia:Muscular_system] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "muscle group" EXACT [] synonym: "muscle system" RELATED [] synonym: "muscles" RELATED [] synonym: "muscles set" EXACT [] synonym: "musculature" EXACT [] synonym: "musculature system" RELATED [] synonym: "musculi" EXACT OMO:0003011 [FMA:32558, FMA:TA] synonym: "set of muscles" EXACT [FMA:32558] synonym: "set of skeletal muscles" EXACT [MA:0000165] xref: AAO:0011066 xref: BTO:0000887 xref: EFO:0001949 xref: EMAPA:32715 xref: EMAPA:35577 xref: FMA:32558 xref: MA:0000165 xref: NCIT:C13056 xref: TAO:0000548 xref: UMLS:C0026845 {source="ncithesaurus:Muscle"} xref: VSAO:0005038 xref: WBbt:0005737 xref: Wikipedia:Muscular_system xref: ZFA:0000548 is_a: UBERON:0011216 ! organ system subdivision relationship: composed_primarily_of UBERON:0001630 ! muscle organ relationship: part_of UBERON:0000383 ! musculature of body property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/e/e5/Muscles_anterior_labeled.png" xsd:anyURI property_value: RO:0002171 UBERON:0001474 property_value: UBPROP:0000012 "In FMA this is classified as a set of organs. ZFA musculature system has subtypes, so it is classified here. WBbt muscular system has subtypes so it goes here. Note that we use the MA term set of skeletal muscles here as it seems most appropriate (*not* MA:musculature). AAO is generally confused here." xsd:string {external_ontology="FMA"} [Term] id: UBERON:0001016 name: nervous system namespace: uberon def: "The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior [CUMBO]." [BIRNLEX:844, ISBN:0-14-051288-8, ISBN:3110148986, NLM:nervous+system, WB:rynl, Wikipedia:Nervous_system, ZFIN:curator] subset: cumbo subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "nerve net" NARROW [Wikipedia:Nerve_net] synonym: "neurological system" EXACT [GO:0050877] synonym: "systema nervosum" RELATED OMO:0003011 [Wikipedia:Nervous_system] xref: AAO:0000324 xref: BILA:0000079 xref: BIRNLEX:844 xref: BTO:0001484 xref: CALOHA:TS-1313 xref: EFO:0000802 xref: EHDAA2:0001246 xref: EHDAA:826 xref: EMAPA:16469 xref: EV:0100162 xref: FBbt:00005093 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:7157 xref: GAID:466 xref: MA:0000016 xref: MAT:0000026 xref: MESH:D009420 xref: MIAA:0000026 xref: NCIT:C12755 xref: neuronames:3236 xref: SCTID:278196006 xref: TAO:0000396 xref: UMLS:C0027763 {source="ncithesaurus:Nervous_System"} xref: VHOG:0000402 xref: WBbt:0005735 xref: Wikipedia:Nervous_system xref: XAO:0000177 xref: ZFA:0000396 is_a: UBERON:0000467 ! anatomical system disjoint_from: UBERON:0001434 ! skeletal system disjoint_from: UBERON:0002204 ! musculoskeletal system disjoint_from: UBERON:0002294 ! biliary system disjoint_from: UBERON:0002330 ! exocrine system disjoint_from: UBERON:0002390 ! hematopoietic system disjoint_from: UBERON:0002405 ! immune system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:8450002 ! excretory system relationship: capable_of GO:0050877 ! nervous system process relationship: composed_primarily_of CL:0002319 ! neural cell relationship: develops_from UBERON:0016880 ! future nervous system relationship: existence_ends_during UBERON:0000066 ! fully formed stage relationship: has_part CL:0000540 ! neuron relationship: immediate_transformation_of UBERON:0016880 {source="Bgee:AN"} ! future nervous system relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/b/b2/TE-Nervous_system_diagram.svg" xsd:anyURI property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/b/ba/Nervous_system_diagram.png" xsd:anyURI property_value: RO:0002161 NCBITaxon:6040 property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "A regulatory system of the body that consists of neurons and neuroglial cells. The nervous system is divided into two parts, the central nervous system (CNS) and the peripheral nervous system (PNS). (Source: BioGlossary, www.Biology-Text.com)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000396", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "Anatomical system consisting of nerve bodies and nerve fibers which regulate the response of the body to external and internal stimuli.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000324", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000003 "Nervous systems evolved in the ancestor of Eumetazoa.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000402", ontology="VHOG", source="ISBN:978-0198566694 Schmidt-Rhaesa A, The evolution of organ systems (2007) p.117", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "nervous" xsd:string property_value: UBPROP:0000007 "neural" xsd:string [Term] id: UBERON:0001017 name: central nervous system namespace: uberon def: "The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord." [GO:0021551, http://www.frontiersinzoology.com/content/7/1/29, https://sourceforge.net/p/geneontology/ontology-requests/11422/] subset: cumbo subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "cerebrospinal axis" NARROW [FMA:55675] synonym: "CNS" EXACT OMO:0003000 [] synonym: "neuraxis" RELATED [FMA:55675] synonym: "systema nervosum centrale" EXACT OMO:0003011 [FMA:55675, FMA:TA] xref: AAO:0000090 xref: BAMS:CNS xref: BILA:0000080 xref: BIRNLEX:1099 xref: BTO:0000227 xref: CALOHA:TS-0150 xref: EFO:0000908 xref: EHDAA2:0000225 xref: EHDAA:828 xref: EMAPA:16470 xref: EMAPA:16754 xref: EV:0100163 xref: FBbt:00005094 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:55675 xref: GAID:570 xref: MA:0000167 xref: MAT:0000457 xref: MESH:D002490 xref: NCIT:C12438 xref: neuronames:854 xref: SCTID:278199004 xref: TAO:0000012 xref: UMLS:C0927232 {source="ncithesaurus:Central_Nervous_System", source="BIRNLEX:1099"} xref: VHOG:0000293 xref: Wikipedia:Central_nervous_system xref: XAO:0000215 xref: ZFA:0000012 is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0011216 {source="FBbt", source="cjm"} ! organ system subdivision relationship: develops_from UBERON:0001049 {gci_relation="part_of", gci_filler="NCBITaxon:7742", evidence="definitional"} ! neural tube relationship: develops_from UBERON:0016879 ! future central nervous system relationship: immediate_transformation_of UBERON:0016879 {source="Bgee:AN"} ! future central nervous system relationship: only_in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of UBERON:0001016 ! nervous system property_value: RO:0002161 NCBITaxon:147099 {source="Wikipedia:Acoelomorpha"} property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Part of the nervous system which includes the brain and spinal cord.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000090", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "The brain and spinal cord. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000012", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "The central nervous system (CNS) is the part of the nervous system which includes the brain, spinal cord, and nerve cell layer of the retina (CUMBO)." xsd:string {source="BIRNLEX:1099"} property_value: UBPROP:0000003 "(...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...) (reference 1); The neural tube is destined to differentiate into the brain and spinal cord (the central nervous system) (reference 2); Taken together, our data make a very strong case that the complex molecular mediolateral architecture of the developing trunk CNS (central nervous system), as shared between Platynereis and vertebrates, was already present in their last common ancestor, Urbilateria. The concept of bilaterian nervous system centralization implies that neuron types concentrate on one side of the trunk, as is the case in vertebrates and many invertebrates including Platynereis, where they segregate and become spatially organized (as opposed to a diffuse nerve net). Our data reveal that a large part of the spatial organization of the annelid and vertebrate CNS was already present in their last common ancestor, which implies that Urbilateria had already possessed a CNS (reference 3).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000293", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28 (reference 1), ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.165 (reference 2), DOI:10.1016/j.cell.2007.02.040 Denes AS, Jekely G, Steinmetz PRH, Raible F, Snyman H, Prud'homme B, Ferrier DEK, Balavoine G and Arendt D, Molecular architecture of annelid nerve cord supports common origin of nervous system centralization in Bilateria. Cell (2007) (reference 3)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001021 name: nerve namespace: uberon def: "An enclosed, cable-like bundle of axons in the peripheral nervous system originating in a nerve root in the central nervous system (or a condensed nervous structure) connecting with peripheral structures." [FBbt:00005105, http://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "nerves" EXACT OMO:0003004 [TAO:0007009] synonym: "neural subtree" RELATED [FMA:65132] synonym: "peripheral nerve" EXACT [http://orcid.org/0000-0002-6601-2165] xref: AAO:0011070 xref: AEO:0000137 xref: BAMS:n xref: BIRNLEX:1615 xref: BSA:0000098 xref: BTO:0000925 xref: BTO:0001027 xref: CALOHA:TS-0772 xref: EHDAA2:0003137 xref: EHDAA:2851 xref: EHDAA:3776 xref: EHDAA:4657 xref: EMAPA:32808 xref: EMAPA:32815 xref: EV:0100371 xref: FBbt:00005105 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:65132 xref: FMA:65239 xref: GAID:747 xref: GAID:758 xref: galen:Nerve xref: MA:0000217 xref: MA:0000228 xref: MESH:D010525 xref: NCIT:C12466 xref: NCIT:C12768 xref: NLX:147826 xref: SCTID:244457007 xref: SCTID:256864008 xref: TAO:0007009 xref: UMLS:C0027740 {source="ncithesaurus:Nerve"} xref: UMLS:C0031119 {source="ncithesaurus:Peripheral_Nerve"} xref: VHOG:0000901 xref: Wikipedia:Nervous_system xref: XAO:0000204 xref: XAO:0003047 xref: ZFA:0007009 is_a: UBERON:0000122 {source="FBbt"} ! neuron projection bundle relationship: has_developmental_contribution_from UBERON:0002342 {gci_relation="part_of", gci_filler="NCBITaxon:7742", source="https://github.com/obophenotype/uberon/wiki/The-neural-crest"} ! neural crest relationship: has_quality PATO:0002045 ! dendritic relationship: part_of UBERON:0000010 ! peripheral nervous system property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "A portion of tissue which is a fasiculated group of axons.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0007009", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000007 "nervous" xsd:string [Term] id: UBERON:0001027 name: sensory nerve namespace: uberon def: "A nerve that transmits from sensory receptors on the surface of the body to the central nervous system." [UBERON:cjm, Wikipedia:Sensory_nerve] subset: pheno_slim subset: uberon_slim synonym: "afferent nerve" RELATED [] synonym: "nervus sensorius" EXACT OMO:0003011 [Wikipedia:Sensory_nerve] xref: AEO:0000201 xref: EHDAA2:0003200 xref: FBbt:00005136 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:5868 xref: Wikipedia:Sensory_nerve is_a: UBERON:0001021 ! nerve relationship: has_part CL:0000526 {source="AEO"} ! afferent neuron [Term] id: UBERON:0001032 name: sensory system namespace: uberon def: "Anatomical system that overlaps the nervous system and is responsible for receiving and processing sensory information." [Wikipedia:Sensory_system] subset: efo_slim subset: uberon_slim subset: vertebrate_core synonym: "organa sensuum" EXACT OMO:0003011 [FMA:75259, FMA:TA] synonym: "organa sensuum" RELATED OMO:0003011 [Wikipedia:Sensory_system] synonym: "sense organ subsystem" EXACT [] synonym: "sense organs" EXACT [FMA:75259] synonym: "sense organs set" EXACT [FMA:75259] synonym: "sensory organ system" RELATED [] synonym: "sensory subsystem" EXACT [] synonym: "sensory systems" EXACT OMO:0003004 [TAO:0000282] synonym: "set of sense organs" RELATED [FMA:75259] xref: AAO:0000555 xref: BAMS:SEN xref: BILA:0000099 xref: EFO:0000805 xref: EHDAA2:0003094 xref: EMAPA:16192 xref: FBbt:00007692 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:75259 xref: MA:0002442 xref: MAT:0000031 xref: MIAA:0000031 xref: NLXANAT:090816 xref: TAO:0000282 xref: VHOG:0001674 xref: Wikipedia:Sensory_system xref: XAO:0003194 xref: ZFA:0000282 is_a: UBERON:0015203 ! non-connected functional system relationship: capable_of_part_of GO:0007600 ! sensory perception relationship: overlaps UBERON:0001016 ! nervous system relationship: part_of UBERON:0004456 ! entire sense organ system property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/c/c0/Gray722.png" xsd:anyURI property_value: UBPROP:0000003 "An early step in the evolution of neural crest, therefore, may have been the origin of a specific dorsal neural cell population contributing to sensory processing; this would predate the divergence of the amphioxus and vertebrate lineages.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001674", ontology="VHOG", source="DOI:10.1073/pnas.97.9.4449 Shimeld SM and Holland PW. Vertebrate innovations. PNAS (2000)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "note the distinct between entire sensory system and individual system. this reconciles is_a and part_of distinctions between ssAOs" xsd:string [Term] id: UBERON:0001040 name: yolk sac namespace: uberon def: "A sac-like expansion of the ventral wall of the intestine, narrowed into a yolk stalk near the body[Hyman's]. Membranous sac attached to an embryo, providing early nourishment in the form of yolk in bony fishes, sharks, reptiles, birds, and primitive mammals. It functions as the developmental circulatory system of the human embryo, before internal circulation begins. In the mouse, the yolk sac is the first site of blood formation, generating primitive macrophages and erythrocytes[WP]." [Wikipedia:Yolk_sac] subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "saccus vitellinus" RELATED OMO:0003011 [Wikipedia:Yolk_sac] synonym: "vesicula umbilicalis" RELATED OMO:0003011 [Wikipedia:Yolk_sac] xref: BTO:0001471 xref: CALOHA:TS-1130 xref: EFO:0003078 xref: EHDAA2:0002212 xref: EHDAA:164 xref: EMAPA:16085 xref: FMA:87180 xref: GAID:1301 xref: MESH:D015017 xref: NCIT:C14128 xref: SCTID:362845002 xref: UMLS:C0043425 {source="ncithesaurus:Yolk_Sac"} xref: VHOG:0000830 xref: Wikipedia:Yolk_sac is_a: UBERON:0005292 ! extraembryonic tissue is_a: UBERON:0005631 {seeAlso="https://github.com/obophenotype/uberon/issues/635"} ! extraembryonic membrane is_a: UBERON:0007499 {source="EHDAA2"} ! epithelial sac relationship: has_developmental_contribution_from UBERON:0000925 {source="ISBN:0073040584"} ! endoderm relationship: has_developmental_contribution_from UBERON:0004872 {source="ISBN:0073040584"} ! splanchnic layer of lateral plate mesoderm property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/1/17/Gray22.png" xsd:anyURI property_value: editor_note "consider splitting class" xsd:string property_value: UBPROP:0000001 "One of the extraembryonic fetal membranes that balloons out from the fetal midgut. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000830", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/yolk+sac"} property_value: UBPROP:0000001 "the extraembryonic tissue membrane, formed from the visceral endoderm and the extraembryonic mesoderm, which is located ventral to the embryonic disc and is connected to the presumptive midgut of the embryo; the yolk that it contains is the site of embryonic hematopoiesis and vitelline circulation is involved in early embryonic circulation; it is the origin of the primordial germ cells" xsd:string {source="MP:0001718"} property_value: UBPROP:0000003 "Structures homologous to the four extraembryonic membranes of reptiles and birds appear in mammals: amnion, chorion, yolk sac, and allantois.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000830", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.187", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "In therians, a structure homologous to the yolk sac is is present, but contains no yolk platelets. Instead it is filled with fluid [ISBN:0073040584 (Vertebrates, Kardong)]" xsd:string [Term] id: UBERON:0001041 name: foregut namespace: uberon def: "Anterior subdivision of a digestive tract." [http://orcid.org/0000-0002-6601-2165] subset: developmental_classification subset: pheno_slim subset: uberon_slim synonym: "praeenteron" RELATED OMO:0003011 [Wikipedia:Foregut] synonym: "proenteron" RELATED OMO:0003011 [Wikipedia:Foregut] xref: AAO:0011042 xref: BILA:0000085 xref: BTO:0000507 xref: EHDAA2:0000557 xref: EHDAA:520 xref: EMAPA:16548 xref: FBbt:00005379 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:45616 xref: MA:0001526 xref: NCIT:C34180 xref: SCTID:361409009 xref: TGMA:0001014 xref: UMLS:C0231051 {source="ncithesaurus:Foregut"} xref: VHOG:0000285 xref: Wikipedia:Foregut xref: XAO:0000232 is_a: UBERON:0004921 ! subdivision of digestive tract property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/9/9a/Gray27.png" xsd:anyURI property_value: editor_note "Note we define this generically to include invertebrates (partly for consistency with GO), but the class may be split in future. In vertebrates the term may refer to a developmental structure" xsd:string property_value: UBPROP:0000001 "The anterior portion of the primitive digestive tube of the embryo that lies cephalic to the junction of the yolk stalk, consists of endodermal tissue, and gives rise to the the pharynx, lower respiratory system, esophagus, stomach, duodenum proximal to the biliary tract, liver, pancreas, biliary tract, and gall bladder." xsd:string {source="MP:0000474"} property_value: UBPROP:0000003 "The bilaterian gut is typically a complete tube that opens to the exterior at both ends. It consists of mouth, foregut, midgut, hindgut, and anus (reference 1); Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000285", ontology="VHOG", source="ISBN:978-0030259821 Ruppert EE, Fox RS, Barnes RD, Invertebrate zoology: a functional evolutionary approach (2003) p.203, ISBN:978-0521617147 Stevens CE and Hume ID, Comparative physiology of the vertebrate digestive system (2004) p.11", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001042 name: chordate pharynx namespace: uberon def: "A portion of the respiratory and digestive tracts; its distal limit is the superior part of the esophagus and it connects the nasal and oral cavities with the esophagus and larynx; it contains the valleculae and the pyriform recesses; its upper limits are the nasal cavity and cranial base.[FEED]." [http://www.feedexp.org] comment: Consider generalizing to deuterostome pharynx subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "pharynx" BROAD SENSU [FMA:46688] xref: AAO:0000967 xref: BTO:0001049 xref: CALOHA:TS-0785 xref: EFO:0000836 xref: EHDAA2:0001458 xref: EHDAA:2947 xref: EMAPA:16706 xref: EV:0100065 xref: FMA:46688 xref: GAID:155 xref: galen:Pharynx xref: MA:0000432 xref: MESH:D010614 xref: NCIT:C12425 xref: SCTID:181211006 xref: TAO:0000056 xref: UMLS:C0031354 {source="ncithesaurus:Pharynx"} xref: VHOG:0000462 xref: Wikipedia:Pharynx xref: XAO:0003227 xref: ZFA:0000056 is_a: UBERON:0006562 ! pharynx relationship: continuous_with UBERON:0001043 {gci_relation="part_of", gci_filler="NCBITaxon:7742"} ! esophagus relationship: develops_from UBERON:0009145 {source="EHDAA2"} ! pharyngeal region of foregut relationship: distally_connected_to UBERON:0001043 {gci_relation="part_of", gci_filler="NCBITaxon:7742"} ! esophagus relationship: has_skeleton UBERON:0008895 {gci_relation="part_of", gci_filler="NCBITaxon:89593"} ! splanchnocranium relationship: only_in_taxon NCBITaxon:7711 ! Chordata relationship: part_of UBERON:0001004 ! respiratory system property_value: UBPROP:0000001 "A funnel-shaped fibromuscular tube that conducts food to the ESOPHAGUS, and air to the LARYNYX and LUNGS. It is located posterior to the NASAL CAVITY; ORAL CAVITY; and LARYNX, and extends from the SKULL BASE to the inferior border of the CRICOID CARTILAGE anteriorly and to the inferior border of the C6 vertebra posteriorly. It is divided into the NASOPHARYNX; OROPHARYNX; and HYPOPHARYNX (laryngopharynx)[MESH:A03.867]." xsd:string {source="MESH:A03.867"} property_value: UBPROP:0000001 "Anatomical cavity bounded by the derivatives of the branchial arches.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000967", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000001 "Swollen region of the anterior foregut, posterior to the mouth and anterior to the liver; its walls form the jaws and gills. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000056", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "Swollen region of the anterior foregut, posterior to the mouth and anterior to the liver; its walls form the jaws and gills[ZFA:0000056, ZFIN:ZDB-PUB-961014-576]." xsd:string {source="ZFIN:ZDB-PUB-961014-576"} property_value: UBPROP:0000001 "The portion of the alimentary canal between the mouth and the oesophagus. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000462", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000002 "relationship type change: part_of_proxy respiratory system (AAO:0000541) CHANGED TO: develops_from respiratory system (UBERON:0001004)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000967", ontology="AAO"} property_value: UBPROP:0000002 "relationship type change: part_of_proxy respiratory system (AAO:0000541) CHANGED TO: part_of respiratory system (UBERON:0001004)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000967", ontology="AAO"} property_value: UBPROP:0000003 "(...) the earliest vertebrates possessed unjointed internal and external branchial arches, and musculature encircling the pharynx.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000462", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) Box essay 13.1 and Box figure I, p.502-503", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "MA/FMA pharynx not part of digestive/alimentary system, we are consistent with this scheme" xsd:string {external_ontology="MA"} [Term] id: UBERON:0001043 name: esophagus namespace: uberon def: "Tube that connects the pharynx to the stomach. In mammals, the oesophagus connects the buccal cavity with the stomach. The stratified squamous non-keratinised epithelium lining the buccal cavity is continued through the pharynx down into the oesophagus. The lowest part of the oesophagus (ca. 2 cm) is lined with gastric mucosa and covered by peritoneum. The main body of the oesophagus is lined with small, simple mucous glands. Each gland opens into the lumen by a long duct which pierces the muscularis mucosae (Wilson and Washington, 1989). A sphincter is situated at the point where the oesophagus enters the stomach to prevent gastro-oesophageal reflux, i.e. to prevent acidic gastric contents from reaching stratified epithelia of the oesophagus, where they can cause inflammation and irritation (Wilson and Washington, 1989; Brown et al., 1993)." [http://www.rivm.nl/interspeciesinfo/inter/oesophagus/, Wikipedia:Esophagus] subset: efo_slim subset: human_reference_atlas subset: major_organ subset: organ_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "gullet" EXACT [] synonym: "oesophagus" EXACT [] xref: AAO:0000145 xref: ANISEED:1235301 xref: BTO:0000959 xref: CALOHA:TS-0700 xref: EFO:0000835 xref: EHDAA2:0001285 xref: EHDAA:2937 xref: EMAPA:16833 xref: EV:0100069 xref: FMA:7131 xref: GAID:291 xref: galen:Esophagus xref: MA:0000352 xref: MAT:0000048 xref: MESH:D004947 xref: MIAA:0000048 xref: NCIT:C12389 xref: SCTID:181245004 xref: TAO:0000204 xref: UMLS:C0014876 {source="ncithesaurus:Esophagus"} xref: VHOG:0000450 xref: Wikipedia:Esophagus xref: XAO:0000127 xref: ZFA:0000204 is_a: UBERON:0004921 ! subdivision of digestive tract is_a: UBERON:0005178 ! thoracic cavity element is_a: UBERON:0013765 ! digestive system element relationship: develops_from UBERON:0001041 ! foregut relationship: distally_connected_to UBERON:0000945 {gci_relation="part_of", gci_filler="NCBITaxon:40674", notes="only in species that have a stomach"} ! stomach relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0004908 ! upper digestive tract relationship: proximally_connected_to UBERON:0001042 ! chordate pharynx property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/d/d4/Illu01_head_neck.jpg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Anterior end of the alimentary canal lined with smooth muscle. Bounded anteriorly by a constriction in the pharynx. Bounded posteriorly by and increase in circular and/or longitudinal smooth muscle associated with the stomach.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000145", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000003 "The few structural specializations in (adult lampreys) pharynx include complex valves on the external gill openings that direct the tidal flow, and the division of the ancestral pharynx into an oesophagus and a respiratory pharynx.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000450", ontology="VHOG", source="DOI:10.1111/j.1096-3642.1996.tb01658.x Mallatt J, Ventilation and the origin of jawed vertebrates: a new mouth. Zoological Journal of the Linnean Society (1996)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "esophageal" xsd:string property_value: UBPROP:0000012 "esophagus NOT part of gut in MA. part of gut in ZFA. part_of gut (via UGIT) in FMA. Consider splitting. Interspecies: The human oesophagus is 25 cm long and has a diameter of ca. 2 cm. Only little information was found on the oesophagus in rat, rabbit and pig. The oesophagus of rat (75 x 2 mm) and rabbit has no mucous glands and the cardia of the stomach has a well-developed sphincter, which prevents them from vomiting (Hebel and Stromberg, 1988; Manning et al., 1994). Morphologically the oesophagus is similar in man and pig; both are omnivores and have a non-keratinised epithelium, submucous glands and similar membrane enzymes. Like in humans, pigs can suffer from reflux oesophagitis and stress ulceration of the oesophagus. The pig oesophagus may therefore be a good model for investigation compared to the human oesophagus (Christie et al., 1995)" xsd:string {external_ontology="MA"} [Term] id: UBERON:0001045 name: midgut namespace: uberon def: "Middle subdivision of a digestive tract[CJM]. In vertebrates: The middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine[GO]." [GO:0007494, Wikipedia:Midgut] subset: developmental_classification subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "mesenteron" RELATED OMO:0003011 [Wikipedia:Midgut] xref: BILA:0000086 xref: BTO:0000863 xref: EFO:0001950 xref: EHDAA2:0001185 xref: EHDAA:983 xref: EMAPA:16255 xref: FBbt:00005383 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:45617 xref: MA:0001564 xref: NCIT:C34210 xref: SCTID:361410004 xref: TGMA:0001036 xref: UMLS:C0231052 {source="ncithesaurus:Midgut"} xref: VHOG:0000290 xref: Wikipedia:Midgut xref: XAO:0000103 is_a: UBERON:0004921 ! subdivision of digestive tract relationship: part_of RO:0002577 ! system relationship: proximally_connected_to UBERON:0001041 ! foregut property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/3/3d/Illu_small_intestine.jpg" xsd:anyURI property_value: editor_note "Note we define this generically to include invertebrates (partly for consistency with GO), but the class may be split in future. We may explicitly make this a developmental class" xsd:string property_value: UBPROP:0000003 "The bilaterian gut is typically a complete tube that opens to the exterior at both ends. It consists of mouth, foregut, midgut, hindgut, and anus (reference 1); Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000290", ontology="VHOG", source="ISBN:978-0030259821 Ruppert EE, Fox RS, Barnes RD, Invertebrate zoology: a functional evolutionary approach (2003) p.203, ISBN:978-0521617147 Stevens CE and Hume ID, Comparative physiology of the vertebrate digestive system (2004) p.11", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "In humans: originates from the foregut at the opening of the bile duct into the duodenum and continues through the small intestine and much of the large intestine until the transition to the hindgut about two-thirds of the way through the transverse colon" xsd:string {source="WP"} property_value: UBPROP:0000012 "in FMA this represents an embryonic region." xsd:string {external_ontology="FMA"} [Term] id: UBERON:0001046 name: hindgut namespace: uberon def: "The caudalmost subdivision of a digestive tract." [http://orcid.org/0000-0002-6601-2165] subset: developmental_classification subset: pheno_slim subset: uberon_slim synonym: "metenteron" RELATED OMO:0003011 [Wikipedia:Hindgut] xref: AAO:0011052 xref: BILA:0000087 xref: BTO:0000510 xref: EHDAA2:0000779 xref: EHDAA:975 xref: EMAPA:16715 xref: FBbt:00005384 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:45618 xref: MA:0001527 xref: NCIT:C34188 xref: SCTID:362856002 xref: TGMA:0001020 xref: UMLS:C0231053 {source="ncithesaurus:Hindgut"} xref: VHOG:0000459 xref: Wikipedia:Hindgut xref: XAO:0000104 is_a: UBERON:0004921 ! subdivision of digestive tract relationship: develops_from UBERON:0003104 {source="Wikipedia"} ! mesenchyme relationship: part_of RO:0002577 ! system relationship: proximally_connected_to UBERON:0001045 ! midgut property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/f/f7/Gray472.png" xsd:anyURI property_value: editor_note "Note we define this generically to include invertebrates (partly for consistency with GO), but the class may be split in future (vertebrates have some contribution from NC - https://github.com/obophenotype/uberon/wiki/The-neural-crest). We may explicitly make this a developmental class" xsd:string property_value: UBPROP:0000001 "the caudal portion of the primitive digestive tube of the embryo" xsd:string {source="MP:0008786"} property_value: UBPROP:0000003 "The bilaterian gut is typically a complete tube that opens to the exterior at both ends. It consists of mouth, foregut, midgut, hindgut, and anus (reference 1); Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000459", ontology="VHOG", source="ISBN:978-0030259821 Ruppert EE, Fox RS, Barnes RD, Invertebrate zoology: a functional evolutionary approach (2003) p.203, ISBN:978-0521617147 Stevens CE and Hume ID, Comparative physiology of the vertebrate digestive system (2004) p.11", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "in FMA this class has no children. In MA it has a single child hindgut epithelium" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0001048 name: primordium namespace: uberon def: "Primordia are populations of contiguous cells that are morphologically distinct and already correspond in extent to a later organ/tissue[FBbt, Hartenstein, V. (2004)]." [BTO:0001886, FB:DJS, FB:FBrf0089570, http://flybase.org/reports/FBrf0178740.html] subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "bud" RELATED [] synonym: "future organ" RELATED [] synonym: "placode" RELATED [FBbt:00005495] synonym: "primordia" RELATED OMO:0003004 [XAO:0003043] synonym: "rudiment" RELATED [] xref: AEO:0000171 xref: BTO:0001886 xref: EFO:0001652 xref: EHDAA2:0003171 xref: FBbt:00005495 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:86589 xref: MAT:0000482 xref: NCIT:C34275 xref: UMLS:C0678727 {source="ncithesaurus:Primordium"} xref: Wikipedia:Primordium xref: XAO:0003043 is_a: UBERON:0005423 {source="EHDAA2"} ! developing anatomical structure relationship: part_of UBERON:0000468 ! multicellular organism [Term] id: UBERON:0001049 name: neural tube namespace: uberon def: "In the developing vertebrate, the neural tube is the embryo's precursor to the central nervous system, which comprises the brain and spinal cord. The neural groove gradually deepens as the neural folds become elevated, and ultimately the folds meet and coalesce in the middle line and convert the groove into a closed tube, the neural tube or neural canal (which strictly speaking is the center of the neural tube), the ectodermal wall of which forms the rudiment of the nervous system. [WP,unvetted]." [Wikipedia:Neural_tube] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "neural primordium" RELATED [] synonym: "presumptive central nervous system" RELATED [] synonym: "tubus neuralis" RELATED OMO:0003011 [Wikipedia:Neural_tube] xref: AAO:0010617 xref: BTO:0001057 xref: CALOHA:TS-2371 xref: DHBA:10154 xref: EHDAA2:0001254 xref: EHDAA:2869 xref: EHDAA:908 xref: EMAPA:16164 xref: EMAPA:16757 xref: FMA:293882 xref: MAT:0000069 xref: MESH:D054259 {sssom:mapping_justification="vocab:ManualMappingCuration", sssom:author_id="https://orcid.org/0000-0001-9439-5346", sssom:mapping_provider="https://github.com/biopragmatics/biomappings"} xref: MIAA:0000069 xref: NCIT:C34226 xref: neuronames:1365 xref: SCTID:362852000 xref: TAO:0001135 xref: UMLS:C0231024 {source="ncithesaurus:Neural_Tube"} xref: VHOG:0000307 xref: Wikipedia:Neural_tube xref: XAO:0003204 xref: ZFA:0001135 is_a: UBERON:0003914 {source="EHDAA2"} ! epithelial tube is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0010371 ! ecto-epithelium is_a: UBERON:0016879 ! future central nervous system relationship: develops_from UBERON:0005068 ! neural rod property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png" xsd:anyURI property_value: UBPROP:0000001 "Hollow epithelial tube on dorsal side of the embryo that develops into the central nervous system.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010617", ontology="AAO", source="AAO:JOR"} property_value: UBPROP:0000001 "The dorsal tubular structure in the vertebrate embryo that develops into the brain and spinal cord. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000307", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/neural+tube"} property_value: UBPROP:0000003 "(...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000307", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28", source="http://bgee.unil.ch/"} property_value: UBPROP:0000011 "The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium" xsd:string {source="GO:0021915"} [Term] id: UBERON:0001052 name: rectum namespace: uberon def: "The terminal portion of the intestinal tube, terminating with the anus." [http://orcid.org/0000-0002-6601-2165, ISBN:0-683-40008-8, MP:0000492] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "intestinum rectum" RELATED [BTO:0001158] synonym: "rectal sac" RELATED [] synonym: "terminal portion of intestine" EXACT [] synonym: "terminal portion of large intestine" RELATED [] xref: AAO:0010401 xref: BTO:0001158 xref: CALOHA:TS-1180 xref: EFO:0000848 xref: EHDAA2:0001592 xref: EHDAA:5836 xref: EMAPA:17896 xref: EV:0100081 xref: FMA:14544 xref: GAID:311 xref: galen:Rectum xref: MA:0000336 xref: MAT:0000050 xref: MESH:D012007 xref: MIAA:0000050 xref: NCIT:C12390 xref: SCTID:181261002 xref: UMLS:C0034896 {source="ncithesaurus:Rectum"} xref: VHOG:0001751 xref: Wikipedia:Rectum xref: XAO:0000238 is_a: UBERON:0004921 {order="4", source="cjm"} ! subdivision of digestive tract relationship: continuous_with UBERON:0001159 ! sigmoid colon relationship: contributes_to_morphology_of UBERON:0000059 ! large intestine relationship: distalmost_part_of UBERON:0000059 {source="ISBN:0073040584"} ! large intestine relationship: part_of UBERON:0000059 {source="MA"} ! large intestine relationship: part_of UBERON:0006866 ! terminal part of digestive tract relationship: part_of UBERON:0012361 {source="EHDAA2"} ! internal anal region property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/7/75/Anorectum.gif" xsd:anyURI property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/SBU_F_Intestine_Large.glb" xsd:anyURI property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/SBU_M_Intestine_Large.glb" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "The terminal portion of the large intestine between the ileo-pelvic colon and the anus. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001751", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "rectal" xsd:string property_value: UBPROP:0000008 "In the lungfish, sharks and rays the rectum opens into the cloaca which also receives wastes (urine) from the kidneys and material from the reproductive organs. In bony fish the rectum reaches the outside environment through the anus, which is normally situated just in front the urinary and reproductive openings. However in some fish the digestive tract may be curled back on itself, and in the Electric Eel (Electrophorus electricus) the anus is situated in the fish's throat. -- http://www.earthlife.net/fish/digestion.html" xsd:string [Term] id: UBERON:0001062 name: anatomical entity namespace: uberon def: "Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species." [FMA:62955, http://orcid.org/0000-0001-9114-8737] subset: common_anatomy subset: human_subset subset: mouse_subset subset: upper_level xref: AAO:0010841 xref: AEO:0000000 xref: BFO:0000004 xref: BILA:0000000 xref: BIRNLEX:6 xref: CARO:0000000 xref: EHDAA2:0002229 xref: FBbt:10000000 {sssom:mapping_justification="vocab:ManualMappingCuration"} xref: FMA:62955 xref: HAO:0000000 xref: MA:0000001 xref: NCIT:C12219 xref: TAO:0100000 xref: TGMA:0001822 xref: UMLS:C1515976 {source="ncithesaurus:Anatomic_Structure_System_or_Substance"} xref: WBbt:0000100 xref: XAO:0000000 xref: ZFA:0100000 is_a: BFO:0000004 ! independent continuant relationship: part_of UBERON:0003942 {gci_filler="GO:0050975", gci_relation="capable_of_part_of"} ! somatosensory system relationship: part_of UBERON:0003942 {gci_relation="capable_of_part_of", gci_filler="GO:0019233"} ! somatosensory system property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0001064 name: ventral pancreatic duct namespace: uberon alt_id: UBERON:0005627 def: "A duct joining the pancreas to the common bile duct to supply pancreatic juices which aid in digestion provided by the exocrine pancreas. The pancreatic duct joins the common bile duct just prior to the ampulla of Vater, after which both ducts perforate the medial side of the second portion of the duodenum at the major duodenal papilla." [Wikipedia:Pancreatic_duct] comment: EDITOR_NOTE in EHDAA2 this is an epithelium, in FMA the wall consists of epithelium and connective tissue subset: human_reference_atlas subset: uberon_slim synonym: "canal of Wirsung" RELATED [BTO:0002362] synonym: "chief pancreatic duct" EXACT [FMA:16003] synonym: "duct of Wirsung" EXACT [Wikipedia:Pancreatic_duct] synonym: "ductus pancreatis ventralis" RELATED [] synonym: "hepaticopancreatic duct" RELATED [BTO:0002362] synonym: "main pancreatic duct" EXACT [MA:0000126] synonym: "pancreatic duct" BROAD [MESH:A03.734.667] xref: BTO:0002362 xref: EHDAA2:0001396 xref: EHDAA:6905 xref: EMAPA:17510 xref: FMA:16003 xref: GAID:337 xref: MA:0000126 xref: MESH:D010183 xref: NCIT:C12272 xref: RETIRED_EHDAA2:0002177 xref: SCTID:245385001 xref: UMLS:C0030288 {source="ncithesaurus:Pancreatic_Duct"} xref: VHOG:0000256 xref: Wikipedia:Pancreatic_duct is_a: UBERON:0000025 ! tube is_a: UBERON:0007329 {source="FMA"} ! pancreatic duct relationship: channel_for UBERON:0001970 ! bile relationship: channels_into UBERON:0004913 ! hepatopancreatic ampulla relationship: continuous_with UBERON:0001174 ! common bile duct relationship: develops_from UBERON:0003924 {source="EHDAA2"} ! ventral pancreatic bud property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/1/15/Gray1100.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000003 "These data show that ducts within the zebrafish pancreas originally arise in situ from isolated progenitor cells rather than arising from reiterative branching of the pancreatic epithelium. This process of pancreatic duct formation in zebrafish may be analogous to the mechanism of duct formation in the mammalian mammary and salivary glands. (...) A related mechanism of duct formation has also been proposed to occur within the mammalian pancreatic epithelium.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000256", ontology="VHOG", source="DOI:10.1016/j.ydbio.2005.04.035 Yee NS, Lorent K, Pack M, Exocrine pancreas development in zebrafish. Developmental Biology (2005)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000011 "Upon reaching its final destination, the ventral pancreatic bud fuses with the much larger dorsal pancreatic bud. At this point of fusion, the main ducts of the ventral and dorsal pancreatic buds fuse, forming the duct of Wirsung, the main pancreatic duct." xsd:string {source="WP"} [Term] id: UBERON:0001068 name: skin of back namespace: uberon def: "A zone of skin that is part of a back [Automatically generated definition]." [OBOL:automatic] comment: EDITOR_NOTE TODO - distinguish between entire skin of region and arbitrary zone of skin on region subset: pheno_slim synonym: "back skin" EXACT [] synonym: "back zone of skin" EXACT [OBOL:automatic] synonym: "skin, dorsal region" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "zone of skin of back" EXACT [OBOL:automatic] xref: EMAPA:36392 xref: FMA:10462 xref: FMA:22985 xref: MA:0000498 xref: SCTID:181492002 is_a: UBERON:0001085 {source="MA"} ! skin of trunk intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0001137 ! dorsum relationship: part_of UBERON:0011270 {source="MA"} ! dorsal trunk [Term] id: UBERON:0001070 name: external carotid artery namespace: uberon def: "A terminal branch of the left or right common carotid artery which supplies oxygenated blood to to the throat, neck glands, tongue, face, mouth, ear, scalp and dura mater of the meninges[MP]." [MGI:anna] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "arteria carotis externa" RELATED OMO:0003011 [Wikipedia:External_carotid_artery] synonym: "external carotid" EXACT [AAO:0010218] xref: AAO:0010218 xref: AAO:0010416 xref: BTO:0004696 xref: EFO:0001953 xref: EHDAA2:0000461 xref: EMAPA:18611 xref: FMA:10635 xref: GAID:480 xref: MA:0001929 xref: MESH:D002342 xref: NCIT:C32551 xref: SCTID:362044002 xref: UMLS:C0007275 {source="ncithesaurus:External_Carotid_Artery"} xref: VHOG:0000265 xref: Wikipedia:External_carotid_artery xref: XAO:0000345 is_a: UBERON:0005396 {source="MA"} ! carotid artery segment relationship: branching_part_of UBERON:0001530 {source="FMA"} ! common carotid artery plus branches relationship: develops_from UBERON:0001530 {source="EHDAA2"} ! common carotid artery plus branches relationship: part_of UBERON:0001530 {source="FMA"} ! common carotid artery plus branches property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/1/13/External_carotid_a.gif" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://sourceforge.net/tracker/?func=detail&aid=3486863&group_id=76834&atid=1127722" xsd:anyURI property_value: UBPROP:0000008 "not homologous to the external carotid of zebrafish (Goodrich, 1958) - http://zfish.nichd.nih.gov/zfatlas/Intro%20Page/comparative.html; check XAO" xsd:string [Term] id: UBERON:0001071 name: superficial cervical artery namespace: uberon def: "It ascends beneath the anterior margin of the trapezius, distributing branches to it, and to the neighboring muscles and lymph glands in the neck, and anastomosing with the superficial branch of the descending branch of the occipital artery." [Wikipedia:Superficial_part_of_transverse_cervical_artery] comment: The transverse cervical artery splits into two branches, a superficial one and a deep one[WP] subset: human_reference_atlas subset: uberon_slim synonym: "superficial branch of transverse cervical artery" EXACT [Wikipedia:Superficial_part_of_transverse_cervical_artery] xref: EMAPA:37117 {source="MA:th"} xref: FMA:10665 xref: MA:0002052 xref: NCIT:C53005 xref: SCTID:161746006 xref: UMLS:C0226271 {source="ncithesaurus:Superficial_Cervical_Artery"} xref: Wikipedia:Superficial_part_of_transverse_cervical_artery is_a: UBERON:0012320 ! cervical artery intersection_of: UBERON:0012320 ! cervical artery intersection_of: part_of UBERON:0035549 ! vasculature of integument relationship: connected_to UBERON:0012324 ! transverse cervical artery relationship: part_of UBERON:0035549 ! vasculature of integument property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001072 name: posterior vena cava namespace: uberon def: "A vein that carries deoxygenated blood from the lower half of the body into the right atrium of the heart." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Inferior_vena_cava] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "caudal vena cava" RELATED [VHOG:0001194] synonym: "inferior caval vein" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "inferior vena cava" EXACT [Wikipedia:Venae_cavae] synonym: "postcava" RELATED [] synonym: "posterior vena cava" EXACT [Wikipedia:Venae_cavae] synonym: "vena cava inferior" RELATED OMO:0003011 [BTO:0002682, Wikipedia:Inferior_vena_cava] xref: AAO:0011083 xref: BTO:0002682 xref: EHDAA2:0000611 xref: EMAPA:18416 xref: FMA:10951 xref: GAID:548 xref: galen:InferiorVenaCava xref: MA:0000480 xref: MESH:D014682 xref: NCIT:C12815 xref: SCTID:181369003 xref: UMLS:C0042458 {source="ncithesaurus:Inferior_Vena_Cava"} xref: VHOG:0001194 xref: Wikipedia:Inferior_vena_cava xref: XAO:0000388 is_a: UBERON:0004087 ! vena cava intersection_of: UBERON:0004087 ! vena cava intersection_of: drains UBERON:0000154 ! posterior region of body disjoint_from: UBERON:0001585 {source="lexical"} ! anterior vena cava relationship: channels_into UBERON:0002078 {gci_relation="part_of", gci_filler="NCBITaxon:40674"} ! right cardiac atrium relationship: connected_to UBERON:0002078 ! right cardiac atrium relationship: develops_from UBERON:0005487 {gci_relation="part_of", gci_filler="NCBITaxon:40674", source="Wikipedia:Vitelline_vein"} ! vitelline vein relationship: drains UBERON:0000154 ! posterior region of body relationship: part_of RO:0002577 ! system property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/4/4d/Gray577.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Trunk of systemic vein which is formed by the union of the right common iliac vein and the left common iliac vein and terminates in the right atrium[FMA]." xsd:string {source="FMA:10951"} property_value: UBPROP:0000003 "Phylogenetic modifications within this basic pattern of arteries and veins are largely correlated with functional changes. In the transition from water to land, gills gave way to lungs, accompanied by the establishment of a pulmonary circulation. In some fishes and certainly in tetrapods, the cardinal veins become less involved in blood return. Instead, the composite, prominent postcava (posterior vena cava) arose to drain the posterior part of the body and the precava (anterior vena cava) developed to drain the anterior part of the body.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001194", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.454-455", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001073 name: ileocecal junction namespace: uberon def: "A point along the course of the gastrointestinal tract where the small intestine (ileum) ends as it opens into the cecal portion of the large intestine; occurs usually within the iliac fossa, demarcated internally as the ileocecal orifice." [http://www.medilexicon.com/medicaldictionary.php?t=46539] synonym: "ileocaecal junction" EXACT [] xref: EMAPA:37601 {source="MA:th"} xref: FMA:11338 xref: MA:0000332 xref: SCTID:264021000 is_a: UBERON:8410024 ! intestinal junction intersection_of: UBERON:0007651 ! anatomical junction intersection_of: connects UBERON:0000059 ! large intestine intersection_of: connects UBERON:0002108 ! small intestine relationship: connects UBERON:0000059 ! large intestine relationship: connects UBERON:0002108 ! small intestine relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata [Term] id: UBERON:0001074 name: pericardial cavity namespace: uberon def: "A potential space between the visceral and parietal layers of the pericardium." [Wikipedia:Pericardium] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "cavitas pericardiaca" RELATED OMO:0003011 [Wikipedia:Pericardial_cavity] synonym: "cavity of pericardial sac" EXACT [] synonym: "pericardial space" EXACT [Wikipedia:Pericardial_cavity] xref: BSA:0000091 xref: EHDAA2:0001434 xref: EMAPA:16131 xref: EMAPA:16132 xref: FMA:11350 xref: galen:PericardialSpace xref: MA:0000053 xref: NCIT:C38662 xref: SCTID:362027001 xref: TAO:0002220 xref: UMLS:C0225972 {source="ncithesaurus:Pericardial_Cavity"} xref: VHOG:0000556 xref: Wikipedia:Pericardial_cavity xref: ZFA:0001655 is_a: UBERON:0002323 {source="MA"} ! coelemic cavity lumen is_a: UBERON:0035809 ! serous cavity intersection_of: UBERON:0002553 ! anatomical cavity intersection_of: luminal_space_of UBERON:0002406 ! pericardial sac relationship: develops_from UBERON:0003887 {source="Wikipedia"} ! intraembryonic coelom relationship: location_of UBERON:0002409 ! pericardial fluid relationship: luminal_space_of UBERON:0002406 ! pericardial sac relationship: part_of UBERON:0002406 {source="FMA"} ! pericardial sac relationship: surrounded_by UBERON:0002357 ! serous pericardium property_value: UBPROP:0000001 "Anatomical space in which the heart is located and is surrounded by the pericardium.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002220", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "In hagfishes a transverse septum extends upward from the ventral body wall posterior to the heart, partly separating an anterior pericardial cavity from a larger peritoneal cavity. (...) These basic relationships have not been modified by urodeles. The small pericardial cavity remains far forward where it is separated by a transverse septum from the principal coelom, which may now be called a pleuroperitoneal cavity because slender lungs are present. (...) The heart (of other tetrapods) is separated from the lungs (and liver if present) by more or less horizontal partitions that have their origin in the embryo as folds on the serous membrane of the right and left lateral body walls. These grow out to join in the midline of the body. They are called lateral mesocardia (birds) or pleuropericardial membranes. Posteriorly they join the transverse septum to form the adult pericardial membrane, or pericardium. (...) In their partitioning of their coelom, embryonic mammals resemble first early fishes (incomplete partition, posterior to heart, consisting of the transverse septum) and then reptiles (pericardium derived from transverse septum and pleuropericardial membranes). Mammals then separate paired pleural cavities from the peritoneal cavity by a diaphragm. The ventral portion of this organ comes from the transverse septum. The dorsal portion is derived from the dorsal mesentery and from still another pair of outgrowths from the lateral body wall, the pleuroperitoneal membranes.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000556", ontology="VHOG", source="ISBN:978-0471090588 Hildebrand M, Analysis of vertebrate structure (1983) p.205-206", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "check ZFA, should actually be thoracic cavity. Note that Hyman defines the cavity as the space between the heart and the sac (but defines the sac as parietal)" xsd:string {external_ontology="ZFA"} [Term] id: UBERON:0001081 name: endocardium of ventricle namespace: uberon def: "Endocardium that is part of the cardiac ventricle." [ZFIN:curator] subset: pheno_slim subset: vertebrate_core synonym: "cardiac ventricle endocardium" EXACT [OBOL:automatic] synonym: "endocardium of cardiac ventricle" EXACT [OBOL:automatic] synonym: "endocardium of heart ventricle" EXACT [OBOL:automatic] synonym: "endocardium of lower chamber of heart" EXACT [OBOL:automatic] synonym: "endocardium of ventricle of heart" EXACT [OBOL:automatic] synonym: "heart ventricle endocardium" EXACT [OBOL:automatic] synonym: "lower chamber of heart endocardium" EXACT [OBOL:automatic] synonym: "ventricle endocardial tissue" RELATED [VHOG:0000607] synonym: "ventricle endocardium" EXACT [] synonym: "ventricle of heart endocardium" EXACT [OBOL:automatic] synonym: "ventricular endocardium" EXACT [] xref: EMAPA:32747 xref: FMA:12148 xref: MA:0000079 xref: SCTID:192172004 xref: TAO:0002247 xref: VHOG:0000607 xref: ZFA:0001615 is_a: UBERON:0000487 ! simple squamous epithelium is_a: UBERON:0002165 ! endocardium is_a: UBERON:0012275 ! meso-epithelium intersection_of: UBERON:0002165 ! endocardium intersection_of: part_of UBERON:0002082 ! cardiac ventricle relationship: contributes_to_morphology_of UBERON:0002082 ! cardiac ventricle relationship: part_of UBERON:0004784 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! heart ventricle wall [Term] id: UBERON:0001082 name: epicardium of ventricle namespace: uberon def: "An epicardial layer that lines a cardiac ventricle." [http://orcid.org/0000-0002-6601-2165] subset: vertebrate_core synonym: "cardiac ventricle epicardium" EXACT [OBOL:automatic] synonym: "ventricular epicardium" EXACT [] xref: FMA:12150 xref: TAO:0005058 xref: ZFA:0005058 is_a: UBERON:0002348 ! epicardium intersection_of: UBERON:0002348 ! epicardium intersection_of: part_of UBERON:0002082 ! cardiac ventricle relationship: part_of UBERON:0002082 ! cardiac ventricle property_value: UBPROP:0000001 "The external layer of the ventricle bounding the ventricular myocardium. It is formed by a single layer of mesothelial cells supported by a basal lamina, and imbricated with collagen, fibroblasts, and vascular structures in the subepicardial space. Hu et al. 2001.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005058", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0001083 name: myocardium of ventricle namespace: uberon def: "Muscular layer of the cardiac ventricle composed of a compact myocardial layer surrounding the trabecular layer." [ZFIN:curator] subset: efo_slim subset: pheno_slim subset: vertebrate_core synonym: "ventricle cardiac muscle" RELATED [VHOG:0000604] synonym: "ventricle myocardium" EXACT [] synonym: "ventricular myocardium" EXACT [] xref: EFO:0003088 xref: EMAPA:32748 xref: FMA:12151 xref: MA:0000082 xref: SCTID:192084000 xref: TAO:0005061 xref: VHOG:0000604 xref: ZFA:0005061 is_a: UBERON:0002349 ! myocardium intersection_of: UBERON:0002349 ! myocardium intersection_of: part_of UBERON:0002082 ! cardiac ventricle relationship: contributes_to_morphology_of UBERON:0002082 ! cardiac ventricle relationship: part_of UBERON:0004784 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! heart ventricle wall property_value: UBPROP:0000001 "Muscular layer of the cardiac ventricle composed of a compact myocardial layer surrounding the trabecular layer Hu et al. 2001.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005061", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "As noted, the hearts of birds and mammals have four chambers that arises from the two chambers (atrium and ventricle) of the fish heart.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000604", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.481", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001084 name: skin of head namespace: uberon def: "A zone of skin that is part of a head [Automatically generated definition]." [OBOL:automatic] comment: EDITOR_NOTE TODO - distinguish between entire skin of region and arbitrary zone of skin on region synonym: "adult head zone of skin" EXACT [OBOL:automatic] synonym: "head skin" EXACT [] synonym: "head zone of skin" EXACT [OBOL:automatic] synonym: "zone of skin of adult head" EXACT [OBOL:automatic] synonym: "zone of skin of head" EXACT [OBOL:automatic] xref: FMA:12166 xref: FMA:24756 xref: MA:0000582 xref: NCIT:C52757 xref: SCTID:181484006 xref: UMLS:C0205029 {source="ncithesaurus:Head_Skin"} is_a: UBERON:0012180 ! head or neck skin intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0000033 ! head relationship: part_of UBERON:0000033 ! head [Term] id: UBERON:0001085 name: skin of trunk namespace: uberon def: "A zone of skin that is part of a trunk [Automatically generated definition]." [OBOL:automatic] comment: EDITOR_NOTE TODO - distinguish between entire skin of region and arbitrary zone of skin on region synonym: "torso zone of skin" EXACT [OBOL:automatic] synonym: "trunk skin" EXACT [] synonym: "trunk zone of skin" EXACT [OBOL:automatic] synonym: "zone of skin of torso" EXACT [OBOL:automatic] synonym: "zone of skin of trunk" EXACT [OBOL:automatic] xref: EMAPA:37278 {source="MA:th"} xref: FMA:12167 xref: FMA:23093 xref: MA:0000517 xref: NCIT:C12295 xref: SCTID:181489001 xref: UMLS:C0205031 {source="ncithesaurus:Skin_of_the_Trunk"} is_a: UBERON:0000014 ! zone of skin intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0002100 ! trunk relationship: part_of UBERON:0002100 ! trunk [Term] id: UBERON:0001087 name: pleural fluid namespace: uberon def: "Transudate contained in the pleural cavity." [FMA:12273] subset: uberon_slim xref: BTO:0003080 xref: FMA:12273 xref: MA:0002532 xref: MAT:0000500 xref: ncithesaurus:Pleural_Fluid xref: Wikipedia:Pleural_fluid is_a: UBERON:0036244 ! secretion of serous membrane intersection_of: UBERON:0007779 ! transudate intersection_of: located_in UBERON:0002402 ! pleural cavity relationship: located_in UBERON:0002402 ! pleural cavity [Term] id: UBERON:0001088 name: urine namespace: uberon def: "Excretion that is the output of a kidney." [https://github.com/geneontology/go-ontology/issues/11025, Wikipedia:Urine] subset: efo_slim subset: pheno_slim subset: uberon_slim xref: BTO:0001419 xref: CALOHA:TS-1092 xref: EFO:0001939 xref: EMAPA:36554 xref: ENVO:00002047 xref: FMA:12274 xref: GAID:1189 xref: galen:Urine xref: MA:0002545 xref: MAT:0000058 xref: MESH:D014556 xref: MIAA:0000058 xref: NCIT:C13283 xref: UMLS:C0042036 {source="ncithesaurus:Urine"} xref: Wikipedia:Urine is_a: UBERON:0000174 ! excreta intersection_of: UBERON:0000174 ! excreta intersection_of: produced_by UBERON:0002113 ! kidney relationship: has_quality PATO:0001548 {gci_relation="part_of", gci_filler="NCBITaxon:40674"} ! quality of a liquid relationship: produced_by UBERON:0002113 ! kidney property_value: UBPROP:0000008 "kidney excreta from some taxa (e.g. in aves) may not be liquid" xsd:string [Term] id: UBERON:0001090 name: synovial fluid namespace: uberon def: "Joint fluid is a transudate of plasma that is actively secreted by synovial cells." [https://www.ncbi.nlm.nih.gov/books/NBK274/] subset: uberon_slim subset: vertebrate_core synonym: "joint fluid" EXACT [https://www.ncbi.nlm.nih.gov/books/NBK274/] xref: BTO:0001339 xref: CALOHA:TS-0996 xref: ENVO:02000039 xref: FMA:12277 xref: GAID:265 xref: galen:SynovialFluid xref: MA:0002544 xref: MESH:D013582 xref: NCIT:C33718 xref: TAO:0005154 xref: UMLS:C0039097 {source="ncithesaurus:Synovial_Fluid"} xref: Wikipedia:Synovial_fluid xref: ZFA:0005154 is_a: UBERON:0007779 ! transudate is_a: UBERON:0007794 {source="FMA"} ! secretion of serous gland intersection_of: UBERON:0007779 ! transudate intersection_of: produced_by CL:0000214 ! synovial cell relationship: has_part CHEBI:16336 ! hyaluronic acid relationship: located_in UBERON:0007617 ! synovial cavity of joint relationship: produced_by CL:0000214 ! synovial cell property_value: UBPROP:0000001 "Portion of organism substance that is a clear fluid that occupies the space in synovial joints.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005154", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000009 "It provides nutrients and lubrication for articular cartilage" xsd:string property_value: UBPROP:0000010 "The fluid contains hyaluronan secreted by fibroblast-like cells in the synovial membrane, lubricin (proteoglycan 4; PRG4) secreted by the surface chondrocytes of the articular cartilage and interstitial fluid filtered from the blood plasma" xsd:string [Term] id: UBERON:0001092 name: vertebral bone 1 namespace: uberon def: "The first vertebral bone in the vertebral column." [http://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "atlas" EXACT [] synonym: "atlas (CI)" EXACT [] synonym: "atlas [C I]" EXACT OMO:0003011 [FMA:12519, FMA:TA] synonym: "atlas vertebra" EXACT [] synonym: "C1" BROAD [] synonym: "C1 vertebra" EXACT [] synonym: "cervical atlas" EXACT [MP:0011576] synonym: "cervical vertebra 1" EXACT HUMAN_PREFERRED [MA:0001421] synonym: "first cervical vertebra" EXACT [] synonym: "vertebra 1" EXACT [TAO:0001167] xref: AAO:0000709 xref: EHDAA:10606 xref: EMAPA:19431 xref: FMA:12519 xref: GAID:236 xref: MA:0001421 xref: MESH:D001270 xref: NCIT:C32239 xref: SCTID:181818007 xref: TAO:0001167 xref: UMLS:C0004170 {source="ncithesaurus:C1_Vertebra"} xref: Wikipedia:Atlas_(anatomy) xref: ZFA:0001167 is_a: UBERON:0002412 ! vertebra relationship: anterior_to UBERON:0001093 ! vertebral bone 2 relationship: anteriorly_connected_to UBERON:0001676 {gci_relation="part_of", gci_filler="NCBITaxon:40674", source="FMA"} ! occipital bone relationship: part_of UBERON:0006072 {gci_relation="part_of", gci_filler="NCBITaxon:32523"} ! cervical region of vertebral column property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "First postcranial vertebra, which is modified anteriorly to articulate with the skull.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000709", ontology="AAO", source="AAO:Duellman_and_Trueb_1994"} property_value: UBPROP:0000001 "Vertebra that is posteriorly adjacent to the neurocranium.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001167", ontology="TAO", source="TAO:wd"} property_value: UBPROP:0000107 "1" xsd:nonNegativeInteger [Term] id: UBERON:0001093 name: vertebral bone 2 namespace: uberon def: "The second vertebral bone in the vertebral column." [http://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "axis" RELATED INCONSISTENT [MA:0001422] synonym: "axis (CII)" EXACT [] synonym: "axis [C II]" EXACT OMO:0003011 [FMA:12520, FMA:TA] synonym: "axis vertebra" EXACT [] synonym: "C2" RELATED [] synonym: "C2 vertebra" NARROW [] synonym: "cervical axis" EXACT [MP:0004608] synonym: "cervical vertebra 2" NARROW HUMAN_PREFERRED [MA:0001422] synonym: "second cervical vertebra" NARROW [] synonym: "vertebra 2" EXACT [ZFA:0001168] xref: EHDAA:10608 xref: EMAPA:19432 xref: FMA:12520 xref: GAID:237 xref: MA:0001422 xref: MESH:D001368 xref: NCIT:C32240 xref: SCTID:181819004 xref: TAO:0001168 xref: UMLS:C0004457 {source="ncithesaurus:C2_Vertebra"} xref: Wikipedia:Axis_(anatomy) xref: ZFA:0001168 is_a: UBERON:0002412 ! vertebra relationship: anteriorly_connected_to UBERON:0001092 {source="FMA"} ! vertebral bone 1 relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0006072 {gci_relation="part_of", gci_filler="NCBITaxon:32523"} ! cervical region of vertebral column property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Vertebra that is posteriorly adjacent to vertebra 1.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001168", ontology="TAO", source="TAO:wd"} property_value: UBPROP:0000013 "not the same as ZFA term 'axis'" xsd:string property_value: UBPROP:0000107 "2" xsd:nonNegativeInteger [Term] id: UBERON:0001095 name: caudal vertebra namespace: uberon alt_id: UBERON:0006070 def: "Any vertebral bone that is part of the caudal region of the vertebral column (tail or coccyx)." [http://orcid.org/0000-0002-6601-2165] comment: Taxon notes In zebrafish, Vertebra bearing a hemal arch and spine. The most posterior caudal vertebrae support the caudal fin and are referred to as preural vertebrae subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "caudal vertebra" BROAD SENSU [FMA:12527] synonym: "caudal vertebrae" EXACT OMO:0003004 [] synonym: "caudal vertebral bone" EXACT [] synonym: "caudal vertebral bone element" EXACT [] synonym: "coccygea" RELATED [MA:0001420] synonym: "coccygeal segment" EXACT [] synonym: "coccygeal vertebra" EXACT [FMA:12527] synonym: "fused tail vertebra" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "tail vertebra" RELATED [MA:0000310] xref: EMAPA:18374 xref: FMA:12527 xref: galen:CoccygealVertebra xref: MA:0000310 xref: MA:0001420 xref: NCIT:C32334 xref: SCTID:361774004 xref: TAO:0000326 xref: UMLS:C0223616 {source="ncithesaurus:Coccygeal_Vertebra"} xref: Wikipedia:Caudal_vertebra xref: XAO:0003079 xref: ZFA:0000326 is_a: UBERON:0002412 ! vertebra is_a: UBERON:0004247 ! bone of dorsum is_a: UBERON:0018142 ! caudal vertebra endochondral element intersection_of: UBERON:0018142 ! caudal vertebra endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Vertebrae bearing a hemal arch and spine. The most posterior caudal vertebrae support the caudal fin and are referred to as preural vertebrae.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000326", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000012 "we deliberately merge the MA classes as we believe them equivalent" xsd:string {external_ontology="MA"} [Term] id: UBERON:0001096 name: wall of esophagus namespace: uberon def: "An anatomical wall that is part of a esophagus [Automatically generated definition]." [OBOL:automatic] synonym: "anatomical wall of esophagus" EXACT [OBOL:automatic] synonym: "anatomical wall of gullet" EXACT [OBOL:automatic] synonym: "anatomical wall of oesophagus" EXACT [OBOL:automatic] synonym: "esophageal wall" EXACT [] synonym: "esophagus anatomical wall" EXACT [OBOL:automatic] synonym: "esophagus wall" EXACT [] synonym: "gullet anatomical wall" EXACT [OBOL:automatic] synonym: "gullet wall" EXACT [OBOL:automatic] synonym: "oesophagus anatomical wall" EXACT [OBOL:automatic] synonym: "oesophagus wall" EXACT [OBOL:automatic] synonym: "wall of gullet" EXACT [OBOL:automatic] synonym: "wall of oesophagus" EXACT [OBOL:automatic] xref: EMAPA:35326 xref: FMA:12611 xref: MA:0002691 is_a: UBERON:0000328 ! gut wall intersection_of: UBERON:0000060 ! anatomical wall intersection_of: part_of UBERON:0001043 ! esophagus relationship: part_of UBERON:0001043 ! esophagus [Term] id: UBERON:0001103 name: diaphragm namespace: uberon def: "A thin musculomebranous barrier that separates the abdominal and thoracic cavities. Often used for breathing control." [MP:0002279] subset: efo_slim subset: organ_slim subset: pheno_slim subset: uberon_slim synonym: "diaphragm muscle" EXACT [BTO:0000341] synonym: "diaphragm of thorax" EXACT [] synonym: "midriff" RELATED [BTO:0000341] synonym: "phren" RELATED [BTO:0000341] synonym: "thoracic diaphragm" EXACT [] xref: BTO:0000341 xref: CALOHA:TS-0198 xref: EFO:0000937 xref: EHDAA2:0003495 xref: EMAPA:17701 xref: EV:0100376 xref: FMA:13295 xref: GAID:158 xref: MA:0001904 xref: MAT:0000502 xref: MESH:D003964 xref: NCIT:C12702 xref: SCTID:181614006 xref: UMLS:C0011980 {source="ncithesaurus:Diaphragm"} xref: VHOG:0000713 xref: Wikipedia:Thoracid_diaphragm is_a: UBERON:0003830 ! thoracic segment muscle is_a: UBERON:0003831 ! respiratory system muscle relationship: develops_from UBERON:0010084 ! future diaphragm relationship: immediate_transformation_of UBERON:0010084 {evidence="definitional"} ! future diaphragm relationship: innervated_by UBERON:0001884 ! phrenic nerve relationship: only_in_taxon NCBITaxon:40674 {source="PMID:23586979"} ! Mammalia property_value: RO:0002161 NCBITaxon:8782 {source="Wikipedia:Thoracic_diaphragm#Comparative_anatomy_and_evolution"} property_value: UBPROP:0000001 "The diaphragm is a skeletal muscle that is responsible for contraction and expansion of the lungs[GO]." xsd:string {source="GO:0060539"} property_value: UBPROP:0000003 "The mammals are characterized by a diaphragm, which separates the thoracic portion of the body cavity from the abdominal region and assists in drawing air into the lungs and forcing it out. Modern reptiles lack a muscu